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Search of human proteins with 17978471
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17978471 ATPase, aminophospholipid transporter (APLT), class
I, type 8A, member 1 isoform a [Homo sapiens]
(1164 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 2334 0.0
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 2264 0.0
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 1613 0.0
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 857 0.0
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 843 0.0
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 823 0.0
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 690 0.0
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 679 0.0
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 678 0.0
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 659 0.0
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 656 0.0
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 656 0.0
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 461 e-129
gi|41327760 ATPase, class II, type 9B [Homo sapiens] 439 e-122
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 418 e-116
gi|149944474 ATPase, class V, type 10B [Homo sapiens] 406 e-113
gi|14424433 ATPase, class V, type 10A [Homo sapiens] 402 e-112
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 278 2e-74
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 93 1e-18
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 93 1e-18
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 92 4e-18
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 89 2e-17
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 88 4e-17
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 88 4e-17
gi|66932949 ATPase type 13A4 [Homo sapiens] 82 2e-15
gi|148839292 ATPase type 13A3 [Homo sapiens] 81 7e-15
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 77 1e-13
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 77 1e-13
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 77 1e-13
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 72 4e-12
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 2334 bits (6048), Expect = 0.0
Identities = 1164/1164 (100%), Positives = 1164/1164 (100%)
Query: 1 MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN 60
MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN
Sbjct: 1 MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN 60
Query: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED
Sbjct: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
Query: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPADLISLSSSEPQAM 180
IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPADLISLSSSEPQAM
Sbjct: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPADLISLSSSEPQAM 180
Query: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH
Sbjct: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
Query: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI
Sbjct: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
Query: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL
Sbjct: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
Query: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ
Sbjct: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
Query: 421 FKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEF 480
FKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEF
Sbjct: 421 FKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEF 480
Query: 481 LTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEER 540
LTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEER
Sbjct: 481 LTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEER 540
Query: 541 YELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFA 600
YELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFA
Sbjct: 541 YELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFA 600
Query: 601 TEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIE 660
TEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIE
Sbjct: 601 TEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIE 660
Query: 661 DKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTR 720
DKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTR
Sbjct: 661 DKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTR 720
Query: 721 ETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ 780
ETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ
Sbjct: 721 ETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ 780
Query: 781 KSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYL 840
KSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYL
Sbjct: 781 KSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYL 840
Query: 841 KNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMF 900
KNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMF
Sbjct: 841 KNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMF 900
Query: 901 TAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPL 960
TAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPL
Sbjct: 901 TAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPL 960
Query: 961 KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV 1020
KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV
Sbjct: 961 KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV 1020
Query: 1021 FFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTL 1080
FFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTL
Sbjct: 1021 FFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTL 1080
Query: 1081 VDEVQELEAKSQDPGAVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQD 1140
VDEVQELEAKSQDPGAVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQD
Sbjct: 1081 VDEVQELEAKSQDPGAVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQD 1140
Query: 1141 ENGIVSQSEVIRAYDTTKQRPDEW 1164
ENGIVSQSEVIRAYDTTKQRPDEW
Sbjct: 1141 ENGIVSQSEVIRAYDTTKQRPDEW 1164
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 2264 bits (5867), Expect = 0.0
Identities = 1137/1164 (97%), Positives = 1142/1164 (98%), Gaps = 15/1164 (1%)
Query: 1 MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN 60
MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN
Sbjct: 1 MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN 60
Query: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED
Sbjct: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
Query: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPADLISLSSSEPQAM 180
IKRHKADNAVNKKQTQVLRNGAWEIVHWEKV VG+IV + E++PAD + LSSSEPQAM
Sbjct: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAM 180
Query: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH
Sbjct: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
Query: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI
Sbjct: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
Query: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL
Sbjct: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
Query: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ
Sbjct: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
Query: 421 FKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEF 480
FKKCTIAGVAYG QNSQFGDEKTFSDSSLLENLQNNHPTAPIICEF
Sbjct: 421 FKKCTIAGVAYG---------------QNSQFGDEKTFSDSSLLENLQNNHPTAPIICEF 465
Query: 481 LTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEER 540
LTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEER
Sbjct: 466 LTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEER 525
Query: 541 YELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFA 600
YELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFA
Sbjct: 526 YELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFA 585
Query: 601 TEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIE 660
TEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIE
Sbjct: 586 TEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIE 645
Query: 661 DKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTR 720
DKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTR
Sbjct: 646 DKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTR 705
Query: 721 ETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ 780
ETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ
Sbjct: 706 ETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ 765
Query: 781 KSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYL 840
KSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYL
Sbjct: 766 KSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYL 825
Query: 841 KNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMF 900
KNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMF
Sbjct: 826 KNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMF 885
Query: 901 TAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPL 960
TAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPL
Sbjct: 886 TAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPL 945
Query: 961 KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV 1020
KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV
Sbjct: 946 KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV 1005
Query: 1021 FFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTL 1080
FFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTL
Sbjct: 1006 FFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTL 1065
Query: 1081 VDEVQELEAKSQDPGAVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQD 1140
VDEVQELEAKSQDPGAVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQD
Sbjct: 1066 VDEVQELEAKSQDPGAVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQD 1125
Query: 1141 ENGIVSQSEVIRAYDTTKQRPDEW 1164
ENGIVSQSEVIRAYDTTKQRPDEW
Sbjct: 1126 ENGIVSQSEVIRAYDTTKQRPDEW 1149
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 1613 bits (4177), Expect = 0.0
Identities = 789/1165 (67%), Positives = 953/1165 (81%), Gaps = 9/1165 (0%)
Query: 4 MRRTVSEIRSRAEGYEKTDD-VSEKTSLADQEEV--RTIFINQPQLTKFCNNHVSTAKYN 60
+R +V +RS GY+K +D +S TS+ DQ E RTI++NQP L KF +N +STAKY+
Sbjct: 21 IRSSVGPVRSSL-GYKKAEDEMSRATSVGDQLEAPARTIYLNQPHLNKFRDNQISTAKYS 79
Query: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
++TFLPRFLY Q RRAAN+FFLFIALLQQIPDVSPTGRYTTLVPL+ IL +A IKEI+ED
Sbjct: 80 VLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVED 139
Query: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPADLISLSSSEPQAM 180
KRHKADNAVNKK+T VLRNG W + W++VAVG+IVKV NG++LPAD++ LSSSEPQAM
Sbjct: 140 FKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAM 199
Query: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
CY+ET+NLDGETNLKIRQGL T+D++ + LM++SG IECE PNRHLYDF GN+ LDG
Sbjct: 200 CYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGK 259
Query: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
V LG DQILLRG QLRNTQWV GIVVYTGHDTKLMQNST PLK SNVE++TNVQIL+
Sbjct: 260 SLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILV 319
Query: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
LF IL+ M+LV S G+ WNR H K+WY+ + NFG N LTFIIL+NNLIPISLL
Sbjct: 320 LFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYNLLTFIILYNNLIPISLL 379
Query: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
VTLEVVK+TQA FINWD DM+Y DT AMARTSNLNEELGQVKY+FSDKTGTLTCN+M
Sbjct: 380 VTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMN 439
Query: 421 FKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQ-FGDEKTFSDSSLLENLQNNHPTAPIICE 479
FKKC+IAGV YGH PE S D + D F D LL+N+++ HPTAP I E
Sbjct: 440 FKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQE 499
Query: 480 FLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEE 539
FLT++AVCHT VPE++GD IIYQA+SPDE ALV+ AK+L FVFT RTP SVII+++GQE+
Sbjct: 500 FLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGFVFTARTPFSVIIEAMGQEQ 559
Query: 540 RYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQF 599
+ +LNVLEF+S RKRMSVIVRTPSG+LRLYCKGAD VI++RL++ SKY E TL HLE F
Sbjct: 560 TFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKDSKYMEETLCHLEYF 619
Query: 600 ATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAI 659
ATEGLRTLC A A++SE++++EW VYQ AST +++R +LEE YE+IEKNL LLGATAI
Sbjct: 620 ATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAI 679
Query: 660 EDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGT 719
ED+LQ VPETI TL+KA+IKIW+LTGDKQETAINIG+SC+L+ +NM +I++ E SLD T
Sbjct: 680 EDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDAT 739
Query: 720 RETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPL 779
R +++HCT LG+ L KEND ALIIDG TLKYAL+F VR+ FLDLALSCKAVICCRVSPL
Sbjct: 740 RAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPL 799
Query: 780 QKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKY 839
QKSE+V++VKK+VK +TLAIGDGANDV MIQTAHVGVGISGNEG+QA N+SDY+IAQF Y
Sbjct: 800 QKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSY 859
Query: 840 LKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVM 899
L+ LL++HGAW+YNRV+KCILYCFYKN+VLYIIE+WFAFVNGFSGQILFERWCIGLYNV+
Sbjct: 860 LEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVI 919
Query: 900 FTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFP 959
FTA+PP TLGIFERSC +E+ML++P+LYK +QN FNTKVFW HC+N L HS+ILFWFP
Sbjct: 920 FTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWFP 979
Query: 960 LKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV 1019
+KAL++ T +G +DYL +GN VYT+VV+TVCLKAGLET+ WT FSH+A+WGS+ W+
Sbjct: 980 MKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLTWL 1039
Query: 1020 VFFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKT 1079
VFFGIYS++WP IP+APDM G+A M+ SS FW+GL +P A L+ DV ++ K T KT
Sbjct: 1040 VFFGIYSTIWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDVAWRAAKHTCKKT 1099
Query: 1080 LVDEVQELEAKSQDPGAVVL----GKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGY 1135
L++EVQELE KS+ G VL GK L ER +L+K + +K L+R SLQQ + HGY
Sbjct: 1100 LLEEVQELETKSRVLGKAVLRDSNGKRLNERDRLIKRLGRKTPPTLFRGSSLQQGVPHGY 1159
Query: 1136 AFSQDENGIVSQSEVIRAYDTTKQR 1160
AFSQ+E+G VSQ EVIRAYDTTK++
Sbjct: 1160 AFSQEEHGAVSQEEVIRAYDTTKKK 1184
>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
Length = 1223
Score = 857 bits (2214), Expect = 0.0
Identities = 455/1085 (41%), Positives = 669/1085 (61%), Gaps = 59/1085 (5%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ +N + T+KYNI+TFLP L+ QF+ AN++FLF+ +LQ IP +S +TT+VPL+
Sbjct: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPA 167
+L + A+K+ +D RHK+DN VN +Q+QVL NG + W V VG+I+K+ N + + A
Sbjct: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
Query: 168 DLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227
DL+ LSSSEP +CYIET+ LDGETN+K+RQ +P TS++ D+ L + G + CE PN
Sbjct: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
Query: 228 LYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKL 287
L F G + PL +LLRG LRNT+W G+V++ G DTKLMQNS K
Sbjct: 241 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 299
Query: 288 SNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-----DWYLNLNYGGASNFGL 342
++++R+ N +L +F L+ M ++ ++G+AIW + W ++ S F L
Sbjct: 300 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGF-L 358
Query: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
+F ++II+ N ++PISL V++EV++ +YFINWD M T A ART+ LNEELGQ
Sbjct: 359 SFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQ 418
Query: 403 VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHV-------------PEPEDYGCSPDEWQN 449
V+YIFSDKTGTLT N+M F KC+I G +YG V PEP D+ +P
Sbjct: 419 VEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNP----- 473
Query: 450 SQFGDEK-TFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGD-KIIYQAASPD 507
D+K F D SLLE ++ P EF ++++CHT + E + + ++ Y+A SPD
Sbjct: 474 --LADKKFLFWDPSLLEAVKIGDPHTH---EFFRLLSLCHTVMSEEKNEGELYYKAQSPD 528
Query: 508 EGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKL 567
EGALV AA+ FVF RTP ++ + +G Y+LL +L+F + RKRMSVIVR P GK+
Sbjct: 529 EGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKI 588
Query: 568 RLYCKGADTVIYDRLAE-TSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVY 626
RLYCKGADT++ DRL T + T+ HL ++A EGLRTL A ++ E ++EW
Sbjct: 589 RLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERR 648
Query: 627 QRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTG 686
+AS + +R +L YE +E N+ LLGATAIEDKLQ VPETI L A+IKIW+LTG
Sbjct: 649 LQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTG 708
Query: 687 DKQETAINIGHSCKLLKKNMGMIVINEG--------SLDGTRETLSRHCTTLGDALRKEN 738
DKQETA+NIG+SCK+L +M + I G L RE + ++G+ ++
Sbjct: 709 DKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQD 768
Query: 739 ----------------DFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKS 782
++AL+I+G +L +AL + FL+ A +CKAVICCRV+PLQK+
Sbjct: 769 KLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKA 828
Query: 783 EVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKN 842
+VVE+VKK K VTLAIGDGANDVSMI+TAH+GVGISG EG+QA +SDYS +QFK+L+
Sbjct: 829 QVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQR 888
Query: 843 LLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTA 902
LL++HG W+Y R+ K + Y FYKN ++ WF F GFS Q +++++ I LYN+++T+
Sbjct: 889 LLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTS 948
Query: 903 MPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKA 962
+P L +G+F++ ++ ++YP+LY+ Q L FN + F++ G++ SV++F+ P
Sbjct: 949 LPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGV 1008
Query: 963 LQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALW-VVF 1021
T + +DY V T +VI V ++ GL+T YWT +H IWGS+A++ +
Sbjct: 1009 FADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAIL 1068
Query: 1022 FGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTL 1080
F ++S+ L+ P G A + W+ ++ V ++ V ++ ++ L
Sbjct: 1069 FAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDL 1128
Query: 1081 VDEVQ 1085
D V+
Sbjct: 1129 SDTVR 1133
>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
Length = 1192
Score = 843 bits (2179), Expect = 0.0
Identities = 456/1094 (41%), Positives = 688/1094 (62%), Gaps = 50/1094 (4%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ +N + T+KYNI+TFLP L+ QF+R AN++FL + +LQ IP++S +TT+VPL+
Sbjct: 27 QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPA 167
++ + A+K+ +D RHK+DN VN +Q++VL N + W V VG+I+K+ N + + A
Sbjct: 87 VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
Query: 168 DLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDI-KDVDSLMRISGRIECESPNR 226
DL+ LSSSEP +CY+ET+ LDGETNLK+R L TS++ D+ L G + CE PN
Sbjct: 147 DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
Query: 227 HLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLK 286
L F+G + L ++I+LRG LRNT W G+V++ G DTKLMQNS K
Sbjct: 207 KLDKFMGILSWKD-SKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFK 265
Query: 287 LSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-DWYLNLNYGGASNFGLNFL 345
++++R+ N +L +F LI + ++ ++G++IW + + +L N G S+ FL
Sbjct: 266 RTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGEKSSVFSGFL 325
Query: 346 TF---IILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
TF II+ N ++PISL V++EV++ +YFINWD M+Y A+ART+ LNEELGQ
Sbjct: 326 TFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNEELGQ 385
Query: 403 VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQN-------SQFGDE 455
++YIFSDKTGTLT N+M FK+C+I G YG V + D + + SQ E
Sbjct: 386 IEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKSQADRE 445
Query: 456 KTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREG-DKIIYQAASPDEGALVRA 514
F D L+E+++ P + EFL ++A+CHT + E ++IYQ SPDEGALV A
Sbjct: 446 FQFFDHHLMESIKMGDPK---VHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALVTA 502
Query: 515 AKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGA 574
A+ F+F RTP+++ I+ LG Y+LL L+F + RKRMSVIVR P G+++LY KGA
Sbjct: 503 ARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSKGA 562
Query: 575 DTVIYDRLAETSKYK-EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSV 633
DT+++++L +++ +T HL +FA EGLRTL A ++ + F+EW + + A+ +
Sbjct: 563 DTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAAT 622
Query: 634 QNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAI 693
+ R ++ YE IE++L LLGATA+EDKLQ+ V ET+ +L A+IKIW+LTGDKQETAI
Sbjct: 623 EERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAI 682
Query: 694 NIGHSCKLLKKNMG-MIVINEGSLDGTRETLSRHCTTLG--------------------- 731
NIG++C +L +M + VI + RE L + L
Sbjct: 683 NIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQLEL 742
Query: 732 DALRKEN---DFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV 788
D++ +E D+ALII+G +L +AL V+ L+LA CK VICCRV+PLQK++VVE+V
Sbjct: 743 DSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELV 802
Query: 789 KKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHG 848
KK VTLAIGDGANDVSMI++AH+GVGISG EGLQA +SDYS AQF+YL+ LL++HG
Sbjct: 803 KKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHG 862
Query: 849 AWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTL 908
W+Y R+ K + Y FYKN ++ WF F GFS Q ++++W I L+N+++T++P L +
Sbjct: 863 RWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAM 922
Query: 909 GIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTA 968
GIF++ +N + P+LYK Q L FN + F++ L+G++ S++LF+ P A Y A
Sbjct: 923 GIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAF-YNVA 981
Query: 969 FGNGK-TSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV-VFFGIYS 1026
+G+ +DY + T +VI V ++ L+TSYWT+ +H+ IWGSIA++ + F ++S
Sbjct: 982 GEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHS 1041
Query: 1027 S-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEV- 1084
+ ++ P G A + W+ +L VAS++ V ++ +K + TL D++
Sbjct: 1042 NGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQIR 1101
Query: 1085 --QELEAKSQDPGA 1096
Q+ + K++ P +
Sbjct: 1102 RWQKAQKKARPPSS 1115
>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
Length = 1251
Score = 823 bits (2126), Expect = 0.0
Identities = 452/1095 (41%), Positives = 650/1095 (59%), Gaps = 59/1095 (5%)
Query: 47 TKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLL 106
+K+ NN + T KYN TF+P L+ QF+RAAN +FL + +LQ +P +S YTTLVPLL
Sbjct: 90 SKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLL 149
Query: 107 FILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLP 166
+L V AIK++++D+ RHK D +N + +V+++G +++ W+++ VG+++++ + +P
Sbjct: 150 VVLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVP 209
Query: 167 ADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSD-IKDVDSLMRISGRIECESPN 225
AD++ LSSSEP ++CY+ET+ LDGETNLK + L T ++ D+L G IECE PN
Sbjct: 210 ADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPN 269
Query: 226 RHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPL 285
L F G + + + PL AD+ILLRG +RNT + HG+V++ G DTK+M+NS
Sbjct: 270 NRLDKFTGTL-FWRNTSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKTRF 328
Query: 286 KLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFG--LN 343
K + ++ + N + +F +LI +S ++G A W + WYL ++ L
Sbjct: 329 KRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYRGFLI 388
Query: 344 FLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQV 403
F +II+ N ++PISL V++EV++ Q++FINWDL M+Y DT A ART+ LNE+LGQ+
Sbjct: 389 FWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQI 448
Query: 404 KYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDE-----WQNSQFGDEKTF 458
YIFSDKTGTLT N+M FKKC I G YG + + + E W N+ + F
Sbjct: 449 HYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSW-NTYADGKLAF 507
Query: 459 SDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQL 518
D L+E +Q+ P + +F ++AVCHT + +R ++ YQAASPDEGALV AA+
Sbjct: 508 YDHYLIEQIQSGKE--PEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAARNF 565
Query: 519 NFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVI 578
F F RT +++ I LG E Y +L +L+F S RKRMS+IVRTP G ++LYCKGADTVI
Sbjct: 566 GFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGADTVI 625
Query: 579 YDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLL 638
Y+RL + K+ T L+ FA E LRTLC EI E +F EW + AS + NR
Sbjct: 626 YERLHRMNPTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDE 685
Query: 639 KLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDK---------- 688
L++ YE IEK+L LLGATAIEDKLQD VPETI L KADIKIW+LTGDK
Sbjct: 686 ALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFA 745
Query: 689 -----QETAINIGHSCKLL-------KKNMGMIV------INEGSLD--GTR-------- 720
++T I G L ++N G + + E G R
Sbjct: 746 CELLTEDTTICYGEDINSLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNRALIITGSW 805
Query: 721 --ETLSRHCTTLGDAL-----RKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVIC 773
E L T L R E + + K A ++ F+DLA C AVIC
Sbjct: 806 LNEILLEKKTKRNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVIC 865
Query: 774 CRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYS 833
CRV+P QK+ VV++VK+ K +TLAIGDGANDV+MI+TAH+GVGISG EG+QA SSDYS
Sbjct: 866 CRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYS 925
Query: 834 IAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCI 893
AQF+YL+ LL++HG W+Y R+ K + Y FYKN ++ W++F NG+S Q +E W I
Sbjct: 926 FAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFI 985
Query: 894 GLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSV 953
LYNV++T++P L +G+ ++ + L++P LY Q L FN K F+V L+G+ S+
Sbjct: 986 TLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSM 1045
Query: 954 ILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWG 1013
ILF+ PL A SDY + + +VITV + GL+TSYWT+ + +I+G
Sbjct: 1046 ILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFG 1105
Query: 1014 SIALWV-VFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKV 1071
SIAL+ + F +S+ + P A +G A+ W+ ++ LL V +
Sbjct: 1106 SIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRF 1165
Query: 1072 IKRTAFKTLVDEVQE 1086
+ T + + D++Q+
Sbjct: 1166 LSMTIWPSESDKIQK 1180
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 690 bits (1781), Expect = 0.0
Identities = 423/1118 (37%), Positives = 638/1118 (57%), Gaps = 80/1118 (7%)
Query: 33 QEEVRTIFINQ---------PQLTKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLF 83
Q + RTI++ PQ KF +N + ++KY + F+P+ L+ QFRR AN +FL
Sbjct: 16 QSDTRTIYVANRFPQNGLYTPQ--KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLI 73
Query: 84 IALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAW 143
I L+Q + D +PT T+ +PL F++ V AIK+ ED RH +DN VN V+R+G
Sbjct: 74 IFLVQLMID-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGL 132
Query: 144 EIVHWEKVAVGEIVKVTNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPAT 203
+ + VG+IV++ E PADL+ LSS C++ T++LDGETNLK +P T
Sbjct: 133 VKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPET 192
Query: 204 SDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTV---PLGADQILLRGAQLRNT 260
+ ++ V +L + IEC+ P LY F+G + + PLG + +LLRGA+L+NT
Sbjct: 193 ALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNT 252
Query: 261 QWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWN 320
+ + G+ VYTG +TK+ N S K S VE+ N ++I ILI+ +++ ++ W
Sbjct: 253 KEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQ 312
Query: 321 RRHSGKD-WYLNL-----NYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFI 374
+ WY N F +FL F++L+N +IPISL VT+E+ KF ++FI
Sbjct: 313 AEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFI 372
Query: 375 NWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGH- 433
WDLD+++E +D A TS+LNEELGQV+Y+F+DKTGTLT N MQF++C+I G+ Y
Sbjct: 373 GWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEI 432
Query: 434 ----VPEPEDYGCSPDEWQNSQFGDEKTFSDSSLLENLQN-----NHPTAP-----IICE 479
VPE G +PD S G+ S S L NL + + T+P +I E
Sbjct: 433 NGRLVPE----GPTPD----SSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKE 484
Query: 480 ---FLTMMAVCHTAV-----PEREGD----------KIIYQAASPDEGALVRAAKQLNFV 521
F +++CHT + GD ++ Y A+SPDE ALV AA ++ V
Sbjct: 485 HDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIV 544
Query: 522 FTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDR 581
F G + +++ + +LG+ ERY+LL++LEF S R+RMSVIV+ PSG+ L+ KGA++ I +
Sbjct: 545 FIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPK 604
Query: 582 LAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLE 641
K T H+++FA +GLRTLC A + + +++E A T++Q R KL
Sbjct: 605 CIGGEIEK--TRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLA 662
Query: 642 ESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKL 701
++ IEK+L LLGATA+ED+LQD+V ETIE L A IK+W+LTGDK ETA+++ SC
Sbjct: 663 AVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGH 722
Query: 702 LKKNMGMI-VINEGSLDGTRETLSRHCTTLGDALRKEN--DFALIIDGKTLKYALTFGVR 758
+ M ++ +IN+ S E L + L + +++ L++DG +L AL
Sbjct: 723 FHRTMNILELINQKSDSECAEQLRQ----LARRITEDHVIQHGLVVDGTSLSLALREH-E 777
Query: 759 QYFLDLALSCKAVICCRVSPLQKSEVVEMVK-KQVKVVTLAIGDGANDVSMIQTAHVGVG 817
+ F+++ +C AV+CCR++PLQK++V+ ++K K +TLA+GDGANDVSMIQ AHVG+G
Sbjct: 778 KLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIG 837
Query: 818 ISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFA 877
I G EG QAA +SDY+IA+FK+L LL +HG + Y R++ + Y FYKN+ + +
Sbjct: 838 IMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQ 897
Query: 878 FVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYK--TSQNALD 935
F FS Q L++ + LYN+ FT++P L + E+ + P LY+ + L
Sbjct: 898 FYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLS 957
Query: 936 FNTKVFWVHCLNGLFHSVILFWFPLKALQYGTA-FGNGKTSDYLLLGNFVYTFVVITVCL 994
T ++W + G H+ I F+ + T+ GNG+ G V+T +VITV +
Sbjct: 958 IKTFLYWT--ILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTV 1015
Query: 995 KAGLETSYWTWFSHIAIWGSIALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWM 1053
K LET +WTW +H+ WGSI + VF Y LWP + + +M L SSG W
Sbjct: 1016 KMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLG-SQNMYFVFIQLLSSGSAWF 1074
Query: 1054 GLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAKS 1091
++ + V L LD++ KV R T ++ Q E +
Sbjct: 1075 AIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQLTETNA 1112
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 679 bits (1752), Expect = 0.0
Identities = 411/1094 (37%), Positives = 616/1094 (56%), Gaps = 68/1094 (6%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ +N + ++KY F+P+ L+ QFRR AN +FL I L+Q I D +PT T+ +PL F
Sbjct: 44 RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIID-TPTSPVTSGLPLFF 102
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPA 167
++ V AIK+ ED RHKADNA+N+ +++G K+ VG+IV V E P
Sbjct: 103 VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162
Query: 168 DLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227
DLI LSS+ C++ T++LDGE++ K + T + + + IECE P
Sbjct: 163 DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPD 222
Query: 228 LYDFVGNIR----LDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSP 283
LY FVG I L+ PLG++ +LLRGA L+NT+ + G+ +YTG +TK+ N S
Sbjct: 223 LYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSK 282
Query: 284 PLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGL- 342
K S VE+ N +++ CILI+ +L+ +V +W + + N L
Sbjct: 283 SQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLF 342
Query: 343 -----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLN 397
+FL F++LFN +IP+S+ VT+E+ KF +YFI WD DM E T + TS+LN
Sbjct: 343 LKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLN 402
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKT 457
EELGQV+YIF+DKTGTLT N M+FK+C I G Y VP G E D
Sbjct: 403 EELGQVEYIFTDKTGTLTENNMEFKECCIEGHVY--VPHVICNGQVLPESSGIDMIDSSP 460
Query: 458 FSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPERE------------GDKIIYQAAS 505
+ E L F + +CHT + + G +Y ++S
Sbjct: 461 SVNGREREEL------------FFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSS 508
Query: 506 PDEGALVRAAKQLNFVFTGRTPDSV--IIDSLGQEERYELLNVLEFTSARKRMSVIVRTP 563
PDE ALV ++L F + R D+ I++ ER+ELL +L F S R+RMSVIV++
Sbjct: 509 PDEVALVEGVQRLGFTYL-RLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSA 567
Query: 564 SGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWR 623
+G++ L+CKGAD+ I+ R+ E K +I + +E+ A EGLRTLC A + + +++
Sbjct: 568 TGEIYLFCKGADSSIFPRVIE-GKVDQIRAR-VERNAVEGLRTLCVAYKRLIQEEYEGIC 625
Query: 624 AVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWI 683
+ Q A ++Q+R KL E+YE IEK+L LLGATA+ED+LQ++ +TIE L KA IK+W+
Sbjct: 626 KLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWV 685
Query: 684 LTGDKQETAINIGHSCKLLKKNMGMIV-----INEGSLDGTRETLSRHCTTLGDALRKEN 738
LTGDK ETA ++CKL ++N ++ I E SL LS+ +L ++N
Sbjct: 686 LTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDN 745
Query: 739 ---------DFALIIDGKTLKYAL-------TFGVRQYFLDLALSCKAVICCRVSPLQKS 782
D+ LIIDG L + + R+ FL++ SC AV+CCR++PLQK+
Sbjct: 746 LSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRMAPLQKA 805
Query: 783 EVVEMVK-KQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLK 841
++V+++K + +TLAIGDGANDVSMI AHVG+G+ G EG QAA +SDY+I +FK+LK
Sbjct: 806 QIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLK 865
Query: 842 NLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFT 901
+L++HG + Y R+S+ + Y FYKN+ + + F GFS Q L++ + LYN+ FT
Sbjct: 866 KMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFT 925
Query: 902 AMPPLTLGIFERSCRKENMLKYPELYK-TSQNALDFNTKVFWVHCLNGLFHSVILFWFPL 960
++P L + E+ + + + P LY+ ++NAL +VF L GLF +++ F+
Sbjct: 926 SLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNAL-LRWRVFIYWTLLGLFDALVFFFGAY 984
Query: 961 KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV 1020
+ T NG+ G V+T +V TV LK L+T YWTW +H IWGS+ +VV
Sbjct: 985 FVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVV 1044
Query: 1021 FFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKT 1079
F ++ +WP + M + SSG W+ ++ + SLL DV+ KV+ R + T
Sbjct: 1045 FSLLWGGVIWPFLNY-QRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPT 1103
Query: 1080 LVDEVQELEAKSQD 1093
+ VQ A+ +D
Sbjct: 1104 ATERVQNGCAQPRD 1117
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 678 bits (1749), Expect = 0.0
Identities = 409/1086 (37%), Positives = 612/1086 (56%), Gaps = 68/1086 (6%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ +N + ++KY F+P+ L+ QFRR AN +FL I L+Q I D +PT T+ +PL F
Sbjct: 44 RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIID-TPTSPVTSGLPLFF 102
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPA 167
++ V AIK+ ED RHKADNA+N+ +++G K+ VG+IV V E P
Sbjct: 103 VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162
Query: 168 DLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227
DLI LSS+ C++ T++LDGE++ K + T + + + IECE P
Sbjct: 163 DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPD 222
Query: 228 LYDFVGNIR----LDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSP 283
LY FVG I L+ PLG++ +LLRGA L+NT+ + G+ +YTG +TK+ N S
Sbjct: 223 LYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSK 282
Query: 284 PLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGL- 342
K S VE+ N +++ CILI+ +L+ +V +W + + N L
Sbjct: 283 SQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLF 342
Query: 343 -----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLN 397
+FL F++LFN +IP+S+ VT+E+ KF +YFI WD DM E T + TS+LN
Sbjct: 343 LKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLN 402
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKT 457
EELGQV+YIF+DKTGTLT N M+FK+C I G Y VP G E D
Sbjct: 403 EELGQVEYIFTDKTGTLTENNMEFKECCIEGHVY--VPHVICNGQVLPESSGIDMIDSSP 460
Query: 458 FSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPERE------------GDKIIYQAAS 505
+ E L F + +CHT + + G +Y ++S
Sbjct: 461 SVNGREREEL------------FFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSS 508
Query: 506 PDEGALVRAAKQLNFVFTGRTPDSV--IIDSLGQEERYELLNVLEFTSARKRMSVIVRTP 563
PDE ALV ++L F + R D+ I++ ER+ELL +L F S R+RMSVIV++
Sbjct: 509 PDEVALVEGVQRLGFTYL-RLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSA 567
Query: 564 SGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWR 623
+G++ L+CKGAD+ I+ R+ E K +I + +E+ A EGLRTLC A + + +++
Sbjct: 568 TGEIYLFCKGADSSIFPRVIE-GKVDQIRAR-VERNAVEGLRTLCVAYKRLIQEEYEGIC 625
Query: 624 AVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWI 683
+ Q A ++Q+R KL E+YE IEK+L LLGATA+ED+LQ++ +TIE L KA IK+W+
Sbjct: 626 KLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWV 685
Query: 684 LTGDKQETAINIGHSCKLLKKNMGMIV-----INEGSLDGTRETLSRHCTTLGDALRKEN 738
LTGDK ETA ++CKL ++N ++ I E SL LS+ +L ++N
Sbjct: 686 LTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDN 745
Query: 739 ---------DFALIIDGKTLKYAL-------TFGVRQYFLDLALSCKAVICCRVSPLQKS 782
D+ LIIDG L + + R+ FL++ SC AV+CCR++PLQK+
Sbjct: 746 LSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRMAPLQKA 805
Query: 783 EVVEMVK-KQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLK 841
++V+++K + +TLAIGDGANDVSMI AHVG+G+ G EG QAA +SDY+I +FK+LK
Sbjct: 806 QIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLK 865
Query: 842 NLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFT 901
+L++HG + Y R+S+ + Y FYKN+ + + F GFS Q L++ + LYN+ FT
Sbjct: 866 KMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFT 925
Query: 902 AMPPLTLGIFERSCRKENMLKYPELYK-TSQNALDFNTKVFWVHCLNGLFHSVILFWFPL 960
++P L + E+ + + + P LY+ ++NAL +VF L GLF +++ F+
Sbjct: 926 SLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNAL-LRWRVFIYWTLLGLFDALVFFFGAY 984
Query: 961 KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV 1020
+ T NG+ G V+T +V TV LK L+T YWTW +H IWGS+ +VV
Sbjct: 985 FVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVV 1044
Query: 1021 FFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKT 1079
F ++ +WP + M + SSG W+ ++ + SLL DV+ KV+ R + T
Sbjct: 1045 FSLLWGGVIWPFLNY-QRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPT 1103
Query: 1080 LVDEVQ 1085
+ VQ
Sbjct: 1104 ATERVQ 1109
>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
Length = 1300
Score = 659 bits (1701), Expect = 0.0
Identities = 394/1117 (35%), Positives = 623/1117 (55%), Gaps = 108/1117 (9%)
Query: 45 QLTKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVP 104
Q K+ N + TAKYN +FLP LY QF R +N FFL I +LQ IPD+S ++ P
Sbjct: 129 QRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTP 188
Query: 105 LLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEH 164
++ +L + A +++++D+ RHK+D A+N + Q+L +++ W+ + VG++V +
Sbjct: 189 MVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNI 248
Query: 165 LPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPAT-SDIKDVDSLMRISGRIECES 223
+PAD++ L+S+EP ++CY+ET ++DGETNLK RQ L T ++ + + G + CE+
Sbjct: 249 VPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEA 308
Query: 224 PNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSP 283
PN ++ FVG + + L +LLRG ++RNT +G+V+Y G DTK+M+N
Sbjct: 309 PNSRMHHFVGCLEWNDK-KYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGKI 367
Query: 284 PLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGG--ASNFG 341
LK + ++ + N ++++F ++ + LV + G + +YL+ +G A+
Sbjct: 368 HLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESF 427
Query: 342 LNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELG 401
F +F+IL + IP+S+ + E + + FI+WD+ M+Y+P D A AR+++LN+ LG
Sbjct: 428 FVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLG 487
Query: 402 QVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPE----PEDYGCSPDEWQNSQFGDEK- 456
QV+YIFSDKTGTLT N++ F KC I+G YG E P++ +P W ++F D K
Sbjct: 488 QVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKE---NPYLW--NKFADGKL 542
Query: 457 TFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAV----PEREGDKIIYQAASPDEGALV 512
F +++LL ++ N A + EF ++A+CHT + P D+++YQAASPDEGALV
Sbjct: 543 LFHNAALLHLVRTNGDEA--VREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALV 600
Query: 513 RAAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCK 572
AA+ +VF RT D+V I LG+E Y++L +++F S RKRMSV+VR P G + LY K
Sbjct: 601 TAARNFGYVFLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTK 660
Query: 573 GADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTS 632
GADTVI++RL + T + L FA E LRTLC A E++E +++W+ +Q AS
Sbjct: 661 GADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASLL 720
Query: 633 VQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETA 692
+QNR L+ QLLGATAIED+LQD VPETI+ L K++IKIW+LTGDKQETA
Sbjct: 721 LQNRAQALQ----------QLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETA 770
Query: 693 INIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKEN----DFALIIDGKT 748
+NIG +C+LL +N M+++ E + ET + L L +E+ AL+I+G
Sbjct: 771 VNIGFACELLSEN--MLILEEKEISRILETYWENSNNL---LTRESLSQVKLALVINGDF 825
Query: 749 LKYALTFGVRQ-------------------------YFLDLALSCKAVICCRVSP----- 778
L L ++ Y L+L C+ +P
Sbjct: 826 LDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAPPAQDS 885
Query: 779 --------LQKSEVVEMVKKQVKVV-----------------------TLAIGDGANDVS 807
LQ+ V++ K V+ TLAIGDGAND++
Sbjct: 886 RARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAIGDGANDIN 945
Query: 808 MIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNI 867
MI+TA VGVG++G EG+QA +SD+ + QF +L+ LL++HG W+Y R+ K + Y FYK++
Sbjct: 946 MIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFFYKSM 1005
Query: 868 VLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELY 927
++++WFA NGF+GQ L+E W + L+N++++ +P L +G+FE+ E L+ PELY
Sbjct: 1006 ASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELY 1065
Query: 928 KTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTF 987
Q FN VF +G+ S++ F+ L + TA G SD+ V
Sbjct: 1066 VVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTL-WISRDTA-GPASFSDHQSFAVVVALS 1123
Query: 988 VVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLW---PAIPMAPDMSGEAAM 1044
++++ ++ L YWT I S+ + + S W + P + + ++
Sbjct: 1124 CLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFLYADLSV 1183
Query: 1045 LFSSGVFWMGLLFIPVAS---LLLDVVYKVIKRTAFK 1078
+ S + + LL + + + L L V++ +K K
Sbjct: 1184 MSSPSILLVVLLSVSINTFPVLALRVIFPALKELRAK 1220
>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
Length = 1119
Score = 656 bits (1693), Expect = 0.0
Identities = 388/1093 (35%), Positives = 594/1093 (54%), Gaps = 80/1093 (7%)
Query: 37 RTIFINQPQLT--------KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQ 88
RT+F+ ++ +FC+N + ++KY + FLP+ L+ QFRR AN +FL I L+Q
Sbjct: 23 RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
Query: 89 QIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHW 148
D +PT T+ +PL F++ V AIK+ ED RH+ADN VNK ++ N
Sbjct: 83 VTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
Query: 149 EKVAVGEIVKVTNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKD 208
EK+ VG++V+V E P DLI LSS CY+ T++LDGE+N K + T +
Sbjct: 142 EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
Query: 209 VDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVP----LGADQILLRGAQLRNTQWVH 264
+S+ + IECE P LY FVG I + + LG + +LL+GA L+NT+ ++
Sbjct: 202 AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
Query: 265 GIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRR-H 323
G+ VYTG +TK+ N K S VE+ N +++ IL+ + VC+ +W +
Sbjct: 262 GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
Query: 324 SGKDWYLNLNYGGASNFGL-----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDL 378
+ + WY + +FL+F++LFN +IP+S+ VT+E+ KF ++FI+WD
Sbjct: 322 NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
Query: 379 DMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPE 438
D + E + A+ TS+LNEELGQV Y+F+DKTGTLT N M+F +C I G Y V +
Sbjct: 382 DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
Query: 439 DYGCSPDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPER---- 494
D G +T + + + N FL + +CHT +
Sbjct: 442 D-------------GLSQTDGTLTYFDKVDKNREEL-----FLRALCLCHTVEIKTNDAV 483
Query: 495 ----EGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQE-ERYELLNVLEF 549
E ++ Y ++SPDE ALV+ AK+ F F G + +++ +E E YELL+ L F
Sbjct: 484 DGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNF 543
Query: 550 TSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCF 609
+ R+RMSVIV+T G + L+CKGAD+ ++ R+ E+T H+E+ A +G RTLC
Sbjct: 544 DAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEI--ELTKVHVERNAMDGYRTLCV 601
Query: 610 AVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPE 669
A EI+ D++ A ++Q+R K+E+ ++ IE N+ L+GATA+EDKLQDQ E
Sbjct: 602 AFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAE 661
Query: 670 TIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTT 729
TIE L A +K+W+LTGDK ETA + ++C+L + N ++ + +++ + R
Sbjct: 662 TIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHEL 721
Query: 730 LGDALRK------------------ENDFALIIDGKTLKYALTFG-------VRQYFLDL 764
L + +K ++ LIIDG TL L + FL +
Sbjct: 722 LIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQI 781
Query: 765 ALSCKAVICCRVSPLQKSEVVEMVKK-QVKVVTLAIGDGANDVSMIQTAHVGVGISGNEG 823
+ C AV+CCR++PLQK+++V MVK + +TL+IGDGANDVSMI +HVG+GI G EG
Sbjct: 782 CMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEG 841
Query: 824 LQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFS 883
QAA +SDYS+ +FK+LK LL+ HG Y R++ + Y FYKN+ + + + F GFS
Sbjct: 842 RQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFS 901
Query: 884 GQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELY-KTSQNA-LDFNTKVF 941
Q L++ + +YN+ FT++P L + E+ + + P LY K S NA L ++
Sbjct: 902 QQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLY 961
Query: 942 WVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETS 1001
W F + F+ Q + NGK G V+T +V TV LK L+T
Sbjct: 962 WTFL--AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTR 1019
Query: 1002 YWTWFSHIAIWGSIALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPV 1060
+WTW +H IWGS+A +V F + +WP + M A + SS W+ ++ +
Sbjct: 1020 FWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQ-QRMYFVFAQMLSSVSTWLAIILLIF 1078
Query: 1061 ASLLLDVVYKVIK 1073
SL +++ V+K
Sbjct: 1079 ISLFPEILLIVLK 1091
>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
Length = 1132
Score = 656 bits (1693), Expect = 0.0
Identities = 388/1093 (35%), Positives = 594/1093 (54%), Gaps = 80/1093 (7%)
Query: 37 RTIFINQPQLT--------KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQ 88
RT+F+ ++ +FC+N + ++KY + FLP+ L+ QFRR AN +FL I L+Q
Sbjct: 23 RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
Query: 89 QIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHW 148
D +PT T+ +PL F++ V AIK+ ED RH+ADN VNK ++ N
Sbjct: 83 VTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
Query: 149 EKVAVGEIVKVTNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKD 208
EK+ VG++V+V E P DLI LSS CY+ T++LDGE+N K + T +
Sbjct: 142 EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
Query: 209 VDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVP----LGADQILLRGAQLRNTQWVH 264
+S+ + IECE P LY FVG I + + LG + +LL+GA L+NT+ ++
Sbjct: 202 AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
Query: 265 GIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRR-H 323
G+ VYTG +TK+ N K S VE+ N +++ IL+ + VC+ +W +
Sbjct: 262 GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
Query: 324 SGKDWYLNLNYGGASNFGL-----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDL 378
+ + WY + +FL+F++LFN +IP+S+ VT+E+ KF ++FI+WD
Sbjct: 322 NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
Query: 379 DMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPE 438
D + E + A+ TS+LNEELGQV Y+F+DKTGTLT N M+F +C I G Y V +
Sbjct: 382 DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
Query: 439 DYGCSPDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPER---- 494
D G +T + + + N FL + +CHT +
Sbjct: 442 D-------------GLSQTDGTLTYFDKVDKNREEL-----FLRALCLCHTVEIKTNDAV 483
Query: 495 ----EGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQE-ERYELLNVLEF 549
E ++ Y ++SPDE ALV+ AK+ F F G + +++ +E E YELL+ L F
Sbjct: 484 DGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNF 543
Query: 550 TSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCF 609
+ R+RMSVIV+T G + L+CKGAD+ ++ R+ E+T H+E+ A +G RTLC
Sbjct: 544 DAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEI--ELTKVHVERNAMDGYRTLCV 601
Query: 610 AVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPE 669
A EI+ D++ A ++Q+R K+E+ ++ IE N+ L+GATA+EDKLQDQ E
Sbjct: 602 AFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAE 661
Query: 670 TIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTT 729
TIE L A +K+W+LTGDK ETA + ++C+L + N ++ + +++ + R
Sbjct: 662 TIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHEL 721
Query: 730 LGDALRK------------------ENDFALIIDGKTLKYALTFG-------VRQYFLDL 764
L + +K ++ LIIDG TL L + FL +
Sbjct: 722 LIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQI 781
Query: 765 ALSCKAVICCRVSPLQKSEVVEMVKK-QVKVVTLAIGDGANDVSMIQTAHVGVGISGNEG 823
+ C AV+CCR++PLQK+++V MVK + +TL+IGDGANDVSMI +HVG+GI G EG
Sbjct: 782 CMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEG 841
Query: 824 LQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFS 883
QAA +SDYS+ +FK+LK LL+ HG Y R++ + Y FYKN+ + + + F GFS
Sbjct: 842 RQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFS 901
Query: 884 GQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELY-KTSQNA-LDFNTKVF 941
Q L++ + +YN+ FT++P L + E+ + + P LY K S NA L ++
Sbjct: 902 QQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLY 961
Query: 942 WVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETS 1001
W F + F+ Q + NGK G V+T +V TV LK L+T
Sbjct: 962 WTFL--AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTR 1019
Query: 1002 YWTWFSHIAIWGSIALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPV 1060
+WTW +H IWGS+A +V F + +WP + M A + SS W+ ++ +
Sbjct: 1020 FWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQ-QRMYFVFAQMLSSVSTWLAIILLIF 1078
Query: 1061 ASLLLDVVYKVIK 1073
SL +++ V+K
Sbjct: 1079 ISLFPEILLIVLK 1091
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 461 bits (1186), Expect = e-129
Identities = 305/1017 (29%), Positives = 515/1017 (50%), Gaps = 97/1017 (9%)
Query: 37 RTIFINQPQLT--KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVS 94
RT+++ P+ ++ N ++ KYN TFLP L++QF+ N +FL +A Q +P++
Sbjct: 39 RTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMR 98
Query: 95 PTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVG 154
YT VPL F+LAV I+E +E+I+ + D VN + L V + VG
Sbjct: 99 LGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVG 158
Query: 155 EIVKVTNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMR 214
+++ V + +PAD+I L +SE C++ T LDGET+ K+R + T + L++
Sbjct: 159 DLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQ 218
Query: 215 ISGRIECESPNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQW---------VHG 265
I + E PN +++FVG + +D + + NT W V G
Sbjct: 219 IRSYVYAEEPNIDIHNFVGTFTRE-------DSDPPISESLSIENTLWAGTVVASGTVVG 271
Query: 266 IVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSG 325
+V+YTG + + + N+++P K+ + N ILF L+ +SLV +H
Sbjct: 272 VVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA------LQHFA 325
Query: 326 KDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPT 385
WYL + + F++LF+N+IPISL V L++ K ++ I D +
Sbjct: 326 GRWYLQI------------IRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI----- 368
Query: 386 DTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYG--HVPEPEDYGCS 443
+ R+S + E+LG++ Y+ +DKTGTLT N M FK+ + VAYG + E + + S
Sbjct: 369 -PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFS 427
Query: 444 PDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGDKI---- 499
Q+ +K + ++ + ++ + E + +A+CH P E + +
Sbjct: 428 IYTQQSQDPPAQKGPTLTTKVRRTMSSR-----VHEAVKAIALCHNVTPVYESNGVTDQA 482
Query: 500 -----------IYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLG-QEERYELLNVL 547
+YQA+SPDE ALV+ + + GR S+ + + G Q + +L +
Sbjct: 483 EAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIF 542
Query: 548 EFTSARKRMSVIVRTPS-GKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRT 606
FT KRM +IVR S G++ Y KGAD V +A +Y + + A EGLR
Sbjct: 543 PFTYESKRMGIIVRDESTGEITFYMKGADVV----MAGIVQYNDWLEEECGNMAREGLRV 598
Query: 607 LCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQ 666
L A ++E +Q++ A Y +A SV +R LK+ E +E ++LL T +ED+LQ
Sbjct: 599 LVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQAD 658
Query: 667 VPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGM----IVINEGSLDGTRET 722
V T+ETL A IK+W+LTGDK ETA + L+ +N + +V N G
Sbjct: 659 VRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRG-------- 710
Query: 723 LSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKS 782
H +A R+++D AL+I G +L+ L + F++LA C AV+CCR +P QK+
Sbjct: 711 -EAHLEL--NAFRRKHDCALVISGDSLEVCLKY-YEYEFMELACQCPAVVCCRCAPTQKA 766
Query: 783 EVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKN 842
++V +++++ +T A+GDG NDVSMIQ + GVG+ G EG QA+ ++D+SI QFK+L
Sbjct: 767 QIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGR 826
Query: 843 LLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTA 902
LLM+HG +Y R + + ++++ + ++ F+ V F+ L++ + I Y+ ++T
Sbjct: 827 LLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTM 886
Query: 903 MPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKA 962
P +L + ++ + E + YPELYK + K F + L ++ + + L
Sbjct: 887 FPVFSL-VLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLL 945
Query: 963 LQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV 1019
+ S+++ + +T +++T L L W W +A S+A ++
Sbjct: 946 FE----------SEFVHIVAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYI 992
>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
Length = 1147
Score = 439 bits (1128), Expect = e-122
Identities = 306/1025 (29%), Positives = 503/1025 (49%), Gaps = 97/1025 (9%)
Query: 35 EVRTIFINQPQLT--KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPD 92
+ RT+++ P+ K N + KYN+ TF+P LY QF+ N +FL I+ Q +P
Sbjct: 114 KARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPA 173
Query: 93 VSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVA 152
+ YT PL F+LAV +E I++ +R + D VN + L V +
Sbjct: 174 LKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQ 233
Query: 153 VGEIVKVTNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSL 212
VG+++ V + +P+D++ L +SE C+I T LDGET+ K++ + T + + L
Sbjct: 234 VGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDL 293
Query: 213 MRISGRIECESPNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQW---------V 263
IS + + P ++ F G + +D + + NT W V
Sbjct: 294 FSISAYVYAQKPQMDIHSFEGTFTRED-------SDPPIHESLSIENTLWASTIVASGTV 346
Query: 264 HGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRH 323
G+V+YTG +T+ + N+++P K+ ++ N LF L+A+S+V
Sbjct: 347 IGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVG--- 403
Query: 324 SGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYE 383
WY NL F++LF+ +IPISL V L++ K + + D ++
Sbjct: 404 ---PWYRNL------------FRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENI--- 445
Query: 384 PTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCS 443
+ RTS + EELG++ Y+ +DKTGTLT N M FK+ + V+YG E
Sbjct: 446 ---PGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHV 502
Query: 444 PDEWQNSQFGDEKTFSDSSLLENLQNNHP-----TAPIICEFLTMMAVCHTAVPEREG-- 496
D + Q + S+ L Q++ P + I E + + +CH P E
Sbjct: 503 RDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRA 562
Query: 497 -----------------DKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDS-LGQE 538
+ YQA+SPDE ALV+ + + R S+ + + GQ
Sbjct: 563 GVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQV 622
Query: 539 ERYELLNVLEFTSARKRMSVIVRTPS-GKLRLYCKGADTVIYDRLAETSKYKEITLKHLE 597
+ +L + FTS KRM VIVR S ++ Y KGAD ++ +Y + +
Sbjct: 623 LSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVA----MSPIVQYNDWLEEECG 678
Query: 598 QFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGAT 657
A EGLRTL A ++E +Q++ + Y +A S+ +R LK+ E +E+ ++LL T
Sbjct: 679 NMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLT 738
Query: 658 AIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLD 717
+ED+LQ V T+E L A IKIW+LTGDK ETA I S L+ + + +
Sbjct: 739 GVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIF------ 792
Query: 718 GTRETLSRHCTTLG-DALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRV 776
R+ SR L +A R+++D AL+I G +L+ L + + F++LA C AV+CCR
Sbjct: 793 --RQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHE-FVELACQCPAVVCCRC 849
Query: 777 SPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQ 836
SP QK+ +V ++++ T AIGDG NDVSMIQ A G+GI G EG QA+ ++D+SI Q
Sbjct: 850 SPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQ 909
Query: 837 FKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLY 896
F+++ LLM+HG +Y R + + ++ +++ ++ F+ V F+ L++ + + Y
Sbjct: 910 FRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGY 969
Query: 897 NVMFTAMPPLTLGIFERSCRKENMLKYPELYK--TSQNALDFNTKVFWVHCLNGLFHSVI 954
++T P +L + ++ + E + YPELYK T +L F T + WV L ++ I
Sbjct: 970 ATIYTMFPVFSL-VLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWV--LISIYQGGI 1026
Query: 955 LFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGS 1014
L + L + S+++ + +T +++T L L W W +A + S
Sbjct: 1027 LMYGALVLFE----------SEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLS 1076
Query: 1015 IALWV 1019
+ +V
Sbjct: 1077 LGCYV 1081
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 418 bits (1075), Expect = e-116
Identities = 246/659 (37%), Positives = 370/659 (56%), Gaps = 65/659 (9%)
Query: 455 EKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRA 514
EK D+ LL + P P+ C + Y+A SPDE ALV A
Sbjct: 696 EKQHGDAGLLNGKAESLPGQPLACN-------------------LCYEAESPDEAALVYA 736
Query: 515 AKQLNFVFTGRTPDSVIID--SLGQEERYELLNVLEFTSARKRMSVIVRTP-SGKLRLYC 571
A+ RTP+ V++D +LG ++LL++L F S RKRMSV+VR P S ++ +Y
Sbjct: 737 ARAYQCTLRSRTPEQVMVDFAALGPLT-FQLLHILPFDSVRKRMSVVVRHPLSNQVVVYT 795
Query: 572 KGADTVIYDRLAETSK-----------YKEITLKHLEQFATEGLRTLCFAVAEISESDFQ 620
KGAD+VI + L+ S +E T KHL+ +A +GLRTLC A +S++++
Sbjct: 796 KGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYA 855
Query: 621 EWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIK 680
EW + A TS+ NR L ES +E L LLGAT IED+LQ+ VPE+IE L KA IK
Sbjct: 856 EWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIK 915
Query: 681 IWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTR-------ETLSRHCTTLGDA 733
IW+LTGDKQETA+NI ++CKLL+ + + ++N S D + L + L +
Sbjct: 916 IWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMSTILKELQKKTQALPEQ 975
Query: 734 LRKENDF-------------ALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ 780
+ D LII GKTL++AL +++ FL+L C+AV+CCR +PLQ
Sbjct: 976 VSLSEDLLQPPVPRDSGLRAGLIITGKTLEFALQESLQKQFLELTSWCQAVVCCRATPLQ 1035
Query: 781 KSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYL 840
KSEVV++V+ ++V+TLAIGDGANDVSMIQ A +G+G+SG EG+QA +SD++++QFK+L
Sbjct: 1036 KSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHL 1095
Query: 841 KNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMF 900
LL++HG W Y R+S ILY FYKN+ + W+ F GFSG + + W + +N++F
Sbjct: 1096 SKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLF 1155
Query: 901 TAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPL 960
T+ PP+ G+ E+ E +++ PELY++ Q + + FW+ L+ + S++ F+ P
Sbjct: 1156 TSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPY 1215
Query: 961 KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV 1020
Q G +D GN + T + V L +E+ TW + I GSI + +
Sbjct: 1216 FTYQ-------GSDTDIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSILSYFL 1268
Query: 1021 FFGIYSSLWPAI--PMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAF 1077
F ++ ++ P P + ML VF++ + +LL VY+V++ + F
Sbjct: 1269 FAIVFGAMCVTCNPPSNPYWIMQEHML--DPVFYLVCILTTSIALLPRFVYRVLQGSLF 1325
Score = 289 bits (739), Expect = 1e-77
Identities = 157/393 (39%), Positives = 233/393 (59%), Gaps = 9/393 (2%)
Query: 49 FCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFI 108
+ NN + T KY ++ F+PR L+ QF RAAN +FLF+ +L +P V + T++PL+ +
Sbjct: 71 YVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVV 130
Query: 109 LAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVH--WEKVAVGEIVKVTNGEHLP 166
L + AIK+ +ED +++K D +N T+V + + W+ V VG+ ++++ E +P
Sbjct: 131 LTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVIP 190
Query: 167 ADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNR 226
AD++ L S++P +C+IETS LDGE+NLK RQ + ++ + S RIECESPN
Sbjct: 191 ADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRIECESPNN 250
Query: 227 HLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLK 286
L F G + V L + +LLRG +RNT+ V GIVVY GH+TK M N++ P K
Sbjct: 251 DLSRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYK 310
Query: 287 LSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGG------ASNF 340
S +ER N +L +L+ M L +VG IW R+ ++ G + F
Sbjct: 311 RSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMHFFNVPEPDGHIISPLLAGF 370
Query: 341 GLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEEL 400
+ F T IIL LIPISL V++E+VK Q YFI D+D + E D+ R N+ E+L
Sbjct: 371 YM-FWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAEDL 429
Query: 401 GQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGH 433
GQ++Y+FSDKTGTLT N M F++C++AG Y H
Sbjct: 430 GQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCH 462
>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
Length = 1461
Score = 406 bits (1043), Expect = e-113
Identities = 231/633 (36%), Positives = 355/633 (56%), Gaps = 49/633 (7%)
Query: 501 YQAASPDEGALVRAAKQLNFVFTGRTPDSVIID-SLGQEERYELLNVLEFTSARKRMSVI 559
Y+A SPDE ALV AA +F RTP+ V + G + LL L F S RKRMSV+
Sbjct: 717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVV 776
Query: 560 VRTP-SGKLRLYCKGADTVIYDRLAETS------------KYKEITLKHLEQFATEGLRT 606
VR P +G++ +Y KGAD+VI D L + + K + T KHL+ +A +GLRT
Sbjct: 777 VRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRT 836
Query: 607 LCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQ 666
LC A +SE DF+ W + + A S+ NR L E+ + +E L LLGAT IED+LQ+
Sbjct: 837 LCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEG 896
Query: 667 VPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRH 726
VP+TI TL +A I++W+LTGDKQETA+NI HSC+LL + + IN + + L+
Sbjct: 897 VPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCA 956
Query: 727 CTTLGD--ALRKEN----------------------DFALIIDGKTLKYALTFGVRQYFL 762
L L+K + + L+IDGKTL + + FL
Sbjct: 957 LEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFL 1016
Query: 763 DLALSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNE 822
+L C++V+CCR +PLQKS +V++V+ +++V+TL+IGDGANDVSMIQ A +G+GISG E
Sbjct: 1017 ELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQE 1076
Query: 823 GLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGF 882
G+QA SSD++I +FK+LK LL++HG W Y+R+++ ++Y YKN+ + W+ F GF
Sbjct: 1077 GMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGF 1136
Query: 883 SGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFW 942
S + + W + +N+ FT++PPL G+ ++ E +L PELYK+ QN+ +N FW
Sbjct: 1137 SSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFW 1196
Query: 943 VHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSY 1002
+ ++ + S+I F+ P A + G D G + T + T+ L +E
Sbjct: 1197 ISMVDAFYQSLICFFIPYLAYK-------GSDIDVFTFGTPINTISLTTILLHQAMEMKT 1249
Query: 1003 WTWFSHIAIWGSIALWVVFFGIYSSLWPAI--PMAPDMSGEAAMLFSSGVFWMGLLFIPV 1060
WT F + + GS ++ + +Y++ P P E + S+ F++ PV
Sbjct: 1250 WTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQL--SNPTFYLVCFLTPV 1307
Query: 1061 ASLLLDVVYKVIKRTAFKTLVDEVQELEAKSQD 1093
+LL + ++ T K+L+ + Q+++ D
Sbjct: 1308 VALLPRYFFLSLQGTCGKSLISKAQKIDKLPPD 1340
Score = 287 bits (734), Expect = 5e-77
Identities = 165/421 (39%), Positives = 233/421 (55%), Gaps = 21/421 (4%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ N T KY + TFLPR L+ QF R AN +FLF+ +L +P + R T++PL
Sbjct: 65 RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVH--WEKVAVGEIVKVTNGEHL 165
+L V IK+ +ED KRH+ D A+N ++ V W+ V VG+ +++ E +
Sbjct: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIV 184
Query: 166 PADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPN 225
PAD++ L SS+P +C++ET++LDGETNLK R + S + I CE PN
Sbjct: 185 PADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIVCEKPN 244
Query: 226 RHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPL 285
HL F G + G + +LLRG +RNT+ GIV+Y GH+TK M N++ P
Sbjct: 245 NHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRY 304
Query: 286 KLSNVERITNVQILILFCILIAMSLVCSVGSAIWN---RRHSGKDW------YLNLNYGG 336
K S +ER N+ I ILI M L+ +VG +IWN H D +L GG
Sbjct: 305 KRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPSALGG 364
Query: 337 ASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNL 396
FLT IIL LIPISL V++E+VK Q +F++ DLD++ E TD + R N+
Sbjct: 365 F----YMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNI 420
Query: 397 NEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGH------VPEPEDYGCSPDEWQNS 450
E+LGQ++YIFSDKTGTLT N M F++CTI G Y H + P++ +EW
Sbjct: 421 AEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQY 480
Query: 451 Q 451
Q
Sbjct: 481 Q 481
>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
Length = 1499
Score = 402 bits (1034), Expect = e-112
Identities = 238/641 (37%), Positives = 361/641 (56%), Gaps = 52/641 (8%)
Query: 493 EREGDKII-YQAASPDEGALVRAAKQLNFVFTGRTPDSVIID--SLGQEERYELLNVLEF 549
E+E ++ + Y+A SPDE ALV AA+ N V R D V ++ LG+ +ELL+ L F
Sbjct: 684 EQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLT-FELLHTLGF 742
Query: 550 TSARKRMSVIVRTP-SGKLRLYCKGADTVIYDRLAETS----------KYKEITLKHLEQ 598
S RKRMSV++R P + ++ +Y KGAD+V+ D L S K + T +L
Sbjct: 743 DSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNV 802
Query: 599 FATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATA 658
+A EGLRTLC A +S+ ++ W + A +S++N L +S +E NL LLGAT
Sbjct: 803 YAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATG 862
Query: 659 IEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDG 718
IED+LQD VPETI L +A ++IW+LTGDKQETA+NI ++CKLL + +I +N S +
Sbjct: 863 IEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEA 922
Query: 719 TRETLSRH-CTTLGDALRKENDF-------------------------ALIIDGKTLKYA 752
L + C L++ + +L+IDG++L YA
Sbjct: 923 CAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYA 982
Query: 753 LTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTA 812
L + FL LA C++V+CCR +PLQKS VV++V+ ++K +TLAIGDGANDVSMIQ A
Sbjct: 983 LEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVA 1042
Query: 813 HVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYII 872
VGVGISG EG+QA +SD+++ +F+YL+ LL++HG W Y+R++ +LY FYKN + +
Sbjct: 1043 DVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGL 1102
Query: 873 EIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQN 932
WF F GFS + ++W + +N++F+++PPL G+ +R +L P+LYK+ QN
Sbjct: 1103 LFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQN 1162
Query: 933 ALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITV 992
++ + FW + + F S++ F P A D G + T ++T
Sbjct: 1163 MEEYRPRTFWFNMADAAFQSLVCFSIPYLAYY-------DSNVDLFTWGTPIVTIALLTF 1215
Query: 993 CLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAI--PMAPDMSGEAAMLFSSGV 1050
L G+ET WTW + I S+ L+ IY++ P P + +A L V
Sbjct: 1216 LLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQA--LLGDPV 1273
Query: 1051 FWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAKS 1091
F++ L PVA+LL + ++ ++ F T + ++L KS
Sbjct: 1274 FYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRKS 1314
Score = 301 bits (771), Expect = 2e-81
Identities = 163/391 (41%), Positives = 236/391 (60%), Gaps = 8/391 (2%)
Query: 51 NNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILA 110
+N + T KY +++FLP+ L+ QF R AN +F+FIALL +P V+ L P+LFILA
Sbjct: 61 DNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILA 120
Query: 111 VAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVH--WEKVAVGEIVKVTNGEHLPAD 168
+ A +++ ED RH++D+ +N V + V+ W+++ VG+ V++ E PAD
Sbjct: 121 ITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPAD 180
Query: 169 LISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHL 228
++ LSSS+P +C+IET+NLDGETNLK RQ + S++ + + + IECE PN L
Sbjct: 181 ILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDL 240
Query: 229 YDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLS 288
F G I D L + +LLRG LRNT V GIV+Y GH+TK + N++ P K S
Sbjct: 241 SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS 300
Query: 289 NVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFG------L 342
+ER N +L +L+ MSL +VG +W R+ K + S+
Sbjct: 301 KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY 360
Query: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
+FLT II+ LIPISL V++E+VK Q YFIN D+ ++ E TD+ R N+ E+LGQ
Sbjct: 361 SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ 420
Query: 403 VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGH 433
++YIFSDKTGTLT N M F++CT++GV Y H
Sbjct: 421 IQYIFSDKTGTLTENKMVFRRCTVSGVEYSH 451
>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
Length = 387
Score = 278 bits (712), Expect = 2e-74
Identities = 147/384 (38%), Positives = 223/384 (58%), Gaps = 31/384 (8%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ +N + T+KYNI+TFLP L+ QF+ AN++FLF+ +LQ IP +S +TT+VPL+
Sbjct: 28 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPA 167
+L + A+K+ +D RHK+DN VN +Q+QVL NG + W V VG+I+K+ N + + A
Sbjct: 88 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
Query: 168 DLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227
DL+ LSSSEP +CYIET+ LDGETN+K+RQ +P TS++ D+ L + G + CE PN
Sbjct: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
Query: 228 LYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKL 287
L F G + PL +LLRG LRNT+W G+V++ G DTKLMQNS K
Sbjct: 208 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 266
Query: 288 SNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-----DWYLNLNYGGASNFGL 342
++++R+ N +L +F L+ M ++ ++G+AIW + W ++ S F L
Sbjct: 267 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGF-L 325
Query: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
+F ++II+ N ++PISL V Y P+ T ++R S G
Sbjct: 326 SFWSYIIILNTVVPISLYV-------------------RYVPSLTWGLSRESG-----GP 361
Query: 403 VKYIFSDKTGTLTCNVMQFKKCTI 426
++ FS K +L N CT+
Sbjct: 362 IELFFSMKMKSLRSNEKSSSSCTV 385
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 93.2 bits (230), Expect = 1e-18
Identities = 124/499 (24%), Positives = 196/499 (39%), Gaps = 119/499 (23%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKT 457
E +G I SDKTGTLT N M + I G+ Y +P P+ +
Sbjct: 454 ETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFL---------------- 497
Query: 458 FSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQ 517
+L+ + N + PE+EG + Q + E AL
Sbjct: 498 ---PKVLDLIVNGIS--------INSAYTSKILPPEKEGG-LPRQVGNKTECAL------ 539
Query: 518 LNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTV 577
L FV + + + + +E+ Y+ V F S RK MS ++R P+G R+Y KGA +
Sbjct: 540 LGFVTDLKQDYQAVRNEVPEEKLYK---VYTFNSVRKSMSTVIRNPNGGFRMYSKGASEI 596
Query: 578 -------IYDRLAETSKYK-----EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAV 625
I DR E +K ++ +E A +GLRT+C A + +++
Sbjct: 597 ILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTE------- 649
Query: 626 YQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILT 685
S +N +L L + IED ++ +VP+ I +A I + ++T
Sbjct: 650 ---PSWDNENEIL----------TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVT 696
Query: 686 GDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALIID 745
GD TA I C +L T GD DF L ++
Sbjct: 697 GDNINTARAIATKCGIL--------------------------TPGD------DF-LCLE 723
Query: 746 GKTLKYAL---TFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVV 795
GK + V Q LD + K + R SP K +V+ + +QV V
Sbjct: 724 GKEFNRLIRNEKGEVEQEKLD-KIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAV 782
Query: 796 TLAIGDGANDVSMIQTAHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYN 853
T GDG ND ++ A VG +GI+G + + A+ + F + +M G Y+
Sbjct: 783 T---GDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYD 838
Query: 854 RVSKCILYCFYKNIVLYII 872
+SK + + N+V I+
Sbjct: 839 SISKFLQFQLTVNVVAVIV 857
Score = 33.1 bits (74), Expect = 1.6
Identities = 27/120 (22%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Query: 105 LLFILAVAAIKEIIEDIKRHKADNAVN-----KKQTQVLRNGAWEIVHWEKVAVGEIVKV 159
+LF + + + D + K + +++ ++RNG + ++ VG+I +V
Sbjct: 155 ILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQV 214
Query: 160 TNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRI 219
G+ LPAD I + ++ + I+ S+L GE++ +++ L + +M SGR+
Sbjct: 215 KYGDLLPADGILIQGNDLK----IDESSLTGESD-HVKKSLDKDPMLLSGTHVMEGSGRM 269
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 93.2 bits (230), Expect = 1e-18
Identities = 124/499 (24%), Positives = 196/499 (39%), Gaps = 119/499 (23%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKT 457
E +G I SDKTGTLT N M + I G+ Y +P P+ +
Sbjct: 454 ETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFL---------------- 497
Query: 458 FSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQ 517
+L+ + N + PE+EG + Q + E AL
Sbjct: 498 ---PKVLDLIVNGIS--------INSAYTSKILPPEKEGG-LPRQVGNKTECAL------ 539
Query: 518 LNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTV 577
L FV + + + + +E+ Y+ V F S RK MS ++R P+G R+Y KGA +
Sbjct: 540 LGFVTDLKQDYQAVRNEVPEEKLYK---VYTFNSVRKSMSTVIRNPNGGFRMYSKGASEI 596
Query: 578 -------IYDRLAETSKYK-----EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAV 625
I DR E +K ++ +E A +GLRT+C A + +++
Sbjct: 597 ILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTE------- 649
Query: 626 YQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILT 685
S +N +L L + IED ++ +VP+ I +A I + ++T
Sbjct: 650 ---PSWDNENEIL----------TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVT 696
Query: 686 GDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALIID 745
GD TA I C +L T GD DF L ++
Sbjct: 697 GDNINTARAIATKCGIL--------------------------TPGD------DF-LCLE 723
Query: 746 GKTLKYAL---TFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVV 795
GK + V Q LD + K + R SP K +V+ + +QV V
Sbjct: 724 GKEFNRLIRNEKGEVEQEKLD-KIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAV 782
Query: 796 TLAIGDGANDVSMIQTAHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYN 853
T GDG ND ++ A VG +GI+G + + A+ + F + +M G Y+
Sbjct: 783 T---GDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYD 838
Query: 854 RVSKCILYCFYKNIVLYII 872
+SK + + N+V I+
Sbjct: 839 SISKFLQFQLTVNVVAVIV 857
Score = 33.1 bits (74), Expect = 1.6
Identities = 27/120 (22%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Query: 105 LLFILAVAAIKEIIEDIKRHKADNAVN-----KKQTQVLRNGAWEIVHWEKVAVGEIVKV 159
+LF + + + D + K + +++ ++RNG + ++ VG+I +V
Sbjct: 155 ILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQV 214
Query: 160 TNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRI 219
G+ LPAD I + ++ + I+ S+L GE++ +++ L + +M SGR+
Sbjct: 215 KYGDLLPADGILIQGNDLK----IDESSLTGESD-HVKKSLDKDPMLLSGTHVMEGSGRM 269
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
sapiens]
Length = 1198
Score = 91.7 bits (226), Expect = 4e-18
Identities = 174/812 (21%), Positives = 305/812 (37%), Gaps = 163/812 (20%)
Query: 102 LVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQT-QVLRNGAWEIVHWEKVAVGEIVKVT 160
L+ ++ ++ V A + ++ + + + ++Q V+R G + ++ VG+I +V
Sbjct: 158 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVK 217
Query: 161 NGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIE 220
G+ LPAD + + ++ + I+ S+L GE++ ++R+ + D D ++ +SG
Sbjct: 218 YGDLLPADGLFIQGNDLK----IDESSLTGESD-QVRKSV-------DKDPML-LSGTHV 264
Query: 221 CESPNRHLYDFVGNIRLDGHGTVPLGA--------DQILLR--GAQLRNTQWVHGIVVYT 270
E R L VG G LGA D+ + GA Q +
Sbjct: 265 MEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGD 324
Query: 271 GHDTKLMQNSTSPPLKLSNVERITNVQI----LILFCI-LIAMSLVCSVGSAIWNRRHSG 325
D K L VQI L++ I +I + L +V + + N+
Sbjct: 325 ADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNK---- 380
Query: 326 KDWYLNLNYGGASNFGLNFLTFIILFNNLIP--ISLLVTLEVVKFTQAYFINWDLDMHYE 383
K W F F+ + + +P + L VT+ + + + +L H +
Sbjct: 381 KPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLD 440
Query: 384 PTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCS 443
+T +G I SDKTGTLT N M + + V Y +P+P
Sbjct: 441 ACET------------MGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSI--- 485
Query: 444 PDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAV--PEREGDKIIY 501
N T ++ + + + T + PE+EG
Sbjct: 486 --------------------------NTKTMELLINAIAINSAYTTKILPPEKEG----- 514
Query: 502 QAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVR 561
A P + L FV + + + +E+ Y+ V F S RK MS +++
Sbjct: 515 --ALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYK---VYTFNSVRKSMSTVIK 569
Query: 562 TPSGKLRLYCKGADTVIY------------DRLAETSKYKEITLKHLEQFATEGLRTLCF 609
P R+Y KGA ++ R+ E+ K +E A +GLRT+C
Sbjct: 570 LPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICV 629
Query: 610 AVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPE 669
A + S +W ++ I L + IED ++ +VPE
Sbjct: 630 AYRDFPSSPEPDW-------------------DNENDILNELTCICVVGIEDPVRPEVPE 670
Query: 670 TIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTT 729
I +A I + ++TGD TA I C ++ + + EG R
Sbjct: 671 AIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCL-EGKEFNRR--------- 720
Query: 730 LGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV- 788
+R E + Q +D + K + R SP K +V+ +
Sbjct: 721 ----IRNEKG----------------EIEQERID-KIWPKLRVLARSSPTDKHTLVKGII 759
Query: 789 ------KKQVKVVTLAIGDGANDVSMIQTAHVG--VGISGNEGLQAANSSDYSIAQFKYL 840
++QV VT GDG ND ++ A VG +GI+G + + A+ + F +
Sbjct: 760 DSTHTEQRQVVAVT---GDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSI 816
Query: 841 KNLLMIHGAWNYNRVSKCILYCFYKNIVLYII 872
+M G Y+ +SK + + N+V I+
Sbjct: 817 VKAVM-WGRNVYDSISKFLQFQLTVNVVAVIV 847
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
sapiens]
Length = 1243
Score = 89.4 bits (220), Expect = 2e-17
Identities = 113/498 (22%), Positives = 185/498 (37%), Gaps = 116/498 (23%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKT 457
E +G I SDKTGTLT N M + + V Y +P+P
Sbjct: 488 ETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSI----------------- 530
Query: 458 FSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAV--PEREGDKIIYQAASPDEGALVRAA 515
N T ++ + + + T + PE+EG A P +
Sbjct: 531 ------------NTKTMELLINAIAINSAYTTKILPPEKEG-------ALPRQVGNKTEC 571
Query: 516 KQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGAD 575
L FV + + + +E+ Y+ V F S RK MS +++ P R+Y KGA
Sbjct: 572 GLLGFVLDLKQDYEPVRSQMPEEKLYK---VYTFNSVRKSMSTVIKLPDESFRMYSKGAS 628
Query: 576 TVIY------------DRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWR 623
++ R+ E+ K +E A +GLRT+C A + S +W
Sbjct: 629 EIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDW- 687
Query: 624 AVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWI 683
++ I L + IED ++ +VPE I +A I + +
Sbjct: 688 ------------------DNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRM 729
Query: 684 LTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALI 743
+TGD TA I C ++ + + EG R +R E
Sbjct: 730 VTGDNINTARAIAIKCGIIHPGEDFLCL-EGKEFNRR-------------IRNEKG---- 771
Query: 744 IDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVT 796
+ Q +D + K + R SP K +V+ + ++QV VT
Sbjct: 772 ------------EIEQERID-KIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVT 818
Query: 797 LAIGDGANDVSMIQTAHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNR 854
GDG ND ++ A VG +GI+G + + A+ + F + +M G Y+
Sbjct: 819 ---GDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVM-WGRNVYDS 874
Query: 855 VSKCILYCFYKNIVLYII 872
+SK + + N+V I+
Sbjct: 875 ISKFLQFQLTVNVVAVIV 892
Score = 31.2 bits (69), Expect = 6.0
Identities = 26/119 (21%), Positives = 62/119 (52%), Gaps = 6/119 (5%)
Query: 102 LVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQT-QVLRNGAWEIVHWEKVAVGEIVKVT 160
L+ ++ ++ V A + ++ + + + ++Q V+R G + ++ VG+I +V
Sbjct: 158 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVK 217
Query: 161 NGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRI 219
G+ LPAD + + ++ + I+ S+L GE++ ++R+ + + +M SGR+
Sbjct: 218 YGDLLPADGLFIQGNDLK----IDESSLTGESD-QVRKSVDKDPMLLSGTHVMEGSGRM 271
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 88.2 bits (217), Expect = 4e-17
Identities = 113/498 (22%), Positives = 192/498 (38%), Gaps = 116/498 (23%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKT 457
E +G I SDKTGTLT N M + + Y +P P
Sbjct: 462 ETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAP-------------------- 501
Query: 458 FSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAV--PEREGDKIIYQAASPDEGALVRAA 515
S+L + + ++ +++ + T + PE+EG + Q + E AL
Sbjct: 502 ---SALTPKILD------LLVHAISINSAYTTKILPPEKEG-ALPRQVGNKTECAL---- 547
Query: 516 KQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGAD 575
L FV + + + + +++ Y+ V F S RK MS ++R P G RL+ KGA
Sbjct: 548 --LGFVLDLKRDFQPVREQIPEDKLYK---VYTFNSVRKSMSTVIRMPDGGFRLFSKGAS 602
Query: 576 TVIYDRLAETSKYK------------EITLKHLEQFATEGLRTLCFAVAEISESDFQEWR 623
++ + ++ K +E A +GLRT+C A + S +W
Sbjct: 603 EILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDW- 661
Query: 624 AVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWI 683
++ + +L + IED ++ +VPE I +A I + +
Sbjct: 662 ------------------DNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRM 703
Query: 684 LTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALI 743
+TGD TA I C +++ + + EG R +R E
Sbjct: 704 VTGDNINTARAIAAKCGIIQPGEDFLCL-EGKEFNRR-------------IRNEKG---- 745
Query: 744 IDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVT 796
+ Q LD K + R SP K +V+ + ++QV VT
Sbjct: 746 ------------EIEQERLDKVWP-KLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVT 792
Query: 797 LAIGDGANDVSMIQTAHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNR 854
GDG ND ++ A VG +GI+G + + A+ + F + +M G Y+
Sbjct: 793 ---GDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDS 848
Query: 855 VSKCILYCFYKNIVLYII 872
+SK + + N+V I+
Sbjct: 849 ISKFLQFQLTVNVVAVIV 866
Score = 32.7 bits (73), Expect = 2.1
Identities = 28/119 (23%), Positives = 61/119 (51%), Gaps = 6/119 (5%)
Query: 102 LVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQT-QVLRNGAWEIVHWEKVAVGEIVKVT 160
L+ ++ ++ V A + ++ + + + ++Q V+RNG V + VG+I +V
Sbjct: 161 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVK 220
Query: 161 NGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRI 219
G+ LPAD + + +++ + I+ S+L GE++ +R+ + +M SGR+
Sbjct: 221 YGDLLPADGVLIQANDLK----IDESSLTGESD-HVRKSADKDPMLLSGTHVMEGSGRM 274
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 88.2 bits (217), Expect = 4e-17
Identities = 113/498 (22%), Positives = 192/498 (38%), Gaps = 116/498 (23%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKT 457
E +G I SDKTGTLT N M + + Y +P P
Sbjct: 462 ETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAP-------------------- 501
Query: 458 FSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAV--PEREGDKIIYQAASPDEGALVRAA 515
S+L + + ++ +++ + T + PE+EG + Q + E AL
Sbjct: 502 ---SALTPKILD------LLVHAISINSAYTTKILPPEKEG-ALPRQVGNKTECAL---- 547
Query: 516 KQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGAD 575
L FV + + + + +++ Y+ V F S RK MS ++R P G RL+ KGA
Sbjct: 548 --LGFVLDLKRDFQPVREQIPEDKLYK---VYTFNSVRKSMSTVIRMPDGGFRLFSKGAS 602
Query: 576 TVIYDRLAETSKYK------------EITLKHLEQFATEGLRTLCFAVAEISESDFQEWR 623
++ + ++ K +E A +GLRT+C A + S +W
Sbjct: 603 EILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDW- 661
Query: 624 AVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWI 683
++ + +L + IED ++ +VPE I +A I + +
Sbjct: 662 ------------------DNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRM 703
Query: 684 LTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALI 743
+TGD TA I C +++ + + EG R +R E
Sbjct: 704 VTGDNINTARAIAAKCGIIQPGEDFLCL-EGKEFNRR-------------IRNEKG---- 745
Query: 744 IDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVT 796
+ Q LD K + R SP K +V+ + ++QV VT
Sbjct: 746 ------------EIEQERLDKVWP-KLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVT 792
Query: 797 LAIGDGANDVSMIQTAHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNR 854
GDG ND ++ A VG +GI+G + + A+ + F + +M G Y+
Sbjct: 793 ---GDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDS 848
Query: 855 VSKCILYCFYKNIVLYII 872
+SK + + N+V I+
Sbjct: 849 ISKFLQFQLTVNVVAVIV 866
Score = 32.7 bits (73), Expect = 2.1
Identities = 28/119 (23%), Positives = 61/119 (51%), Gaps = 6/119 (5%)
Query: 102 LVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQT-QVLRNGAWEIVHWEKVAVGEIVKVT 160
L+ ++ ++ V A + ++ + + + ++Q V+RNG V + VG+I +V
Sbjct: 161 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVK 220
Query: 161 NGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRI 219
G+ LPAD + + +++ + I+ S+L GE++ +R+ + +M SGR+
Sbjct: 221 YGDLLPADGVLIQANDLK----IDESSLTGESD-HVRKSADKDPMLLSGTHVMEGSGRM 274
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 82.4 bits (202), Expect = 2e-15
Identities = 84/356 (23%), Positives = 156/356 (43%), Gaps = 60/356 (16%)
Query: 539 ERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEIT---LKH 595
E +L+ F+SA +RM+VIV+ G + KGA +R+A + + + +
Sbjct: 591 EGIAILHQFPFSSALQRMTVIVQEMGGDRLAFMKGAP----ERVASFCQPETVPTSFVSE 646
Query: 596 LEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLG 655
L+ + T+G R + A ++ E+D A+T + E +E +L LG
Sbjct: 647 LQIYTTQGFRVIALAYKKL-END--------HHATTLTR----------ETVESDLIFLG 687
Query: 656 ATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVI---- 711
+E++L+++ +E L+ A I+ ++TGD +TAI + ++ ++ +I+I
Sbjct: 688 LLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANE 747
Query: 712 ----NEGSLDGTRETLSRHCT--------TLGDALR---KENDFALIIDGKTLKYALTFG 756
+ S+ T +H + D + +E + + GK+
Sbjct: 748 TTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHV----- 802
Query: 757 VRQYFLDLA--LSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHV 814
+ Q+F L + I R+SP QKS +VE +K V + GDGAND ++ AHV
Sbjct: 803 ISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMC-GDGANDCGALKMAHV 861
Query: 815 GVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLY 870
G+ +S E A+ + + N+ + R + +C +K + LY
Sbjct: 862 GISLSEQEASVASPFTSKT-------PNIECVPHLIKEGRAALVTSFCMFKYMALY 910
>gi|148839292 ATPase type 13A3 [Homo sapiens]
Length = 1226
Score = 80.9 bits (198), Expect = 7e-15
Identities = 124/531 (23%), Positives = 215/531 (40%), Gaps = 92/531 (17%)
Query: 479 EFLTMMAVCHTAVPER---EGDKI----------IYQAASPDEGAL--------VRAAKQ 517
+F+ MA CH+ GD + I + A+ +E AL VR KQ
Sbjct: 537 QFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVRPPKQ 596
Query: 518 LNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSG-KLRLYCKGADT 576
L T + + L ++ F+SA +RMSV+ R K+ Y KGA
Sbjct: 597 LLPESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPE 656
Query: 577 VIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNR 636
I L + LE F +G R + A ++ W VQN
Sbjct: 657 AIAG-LCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESK--LTWH--------KVQNI 705
Query: 637 LLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIG 696
S + IE N+ +G +++KL+ + P +E L KA+I+ ++TGD TA+++
Sbjct: 706 ------SRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVA 759
Query: 697 HSCKLLKKNMGMIVINE-GSLDGTRETLSRH-------CT-----------------TLG 731
C ++ +I+ DG ++ H C+ +L
Sbjct: 760 RDCGMILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLE 819
Query: 732 DALRKENDFALIIDGKTLKYALTFGVRQYFLDLA--LSCKAVICCRVSPLQKSEVVEMVK 789
D FA+ +GK+ L ++F DL L + R++P QK++++E ++
Sbjct: 820 DLQMTRYHFAM--NGKSFSVIL-----EHFQDLVPKLMLHGTVFARMAPDQKTQLIEALQ 872
Query: 790 KQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGA 849
V + GDGAND ++ AH G+ +S L+A+ +S ++ ++ +
Sbjct: 873 NVDYFVGMC-GDGANDCGALKRAHGGISLS---ELEASVASPFT----SKTPSISCVPNL 924
Query: 850 WNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLG 909
R + +C +K + LY I +F+ +S IL +G + +F + + +
Sbjct: 925 IREGRAALITSFCVFKFMALYSIIQYFSVTLLYS--ILSN---LGDFQFLFIDLAIILVV 979
Query: 910 IFERSCR---KENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFW 957
+F S KE + + P S AL F+ + C+ F S+ FW
Sbjct: 980 VFTMSLNPAWKELVAQRPPSGLIS-GALLFSVLSQIIICIG--FQSLGFFW 1027
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 77.0 bits (188), Expect = 1e-13
Identities = 116/498 (23%), Positives = 193/498 (38%), Gaps = 115/498 (23%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKT 457
E +G I SDKTGTLT N M + I Y VPEPE
Sbjct: 464 ETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPE------------------- 504
Query: 458 FSDSSLLENLQNNHPTA-PIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAK 516
++ N+ + T + C + + + PE+EG + + E AL+
Sbjct: 505 ----AIPPNILSYLVTGISVNCAYTSKILP-----PEKEGG-LPRHVGNKTECALLGLLL 554
Query: 517 QLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADT 576
L + + + + +E Y+ V F S RK MS +++ G R++ KGA
Sbjct: 555 DLKRDYQD------VRNEIPEEALYK---VYTFNSVRKSMSTVLKNSDGSYRIFSKGASE 605
Query: 577 VIYDR----LAETSKYK--------EITLKHLEQFATEGLRTLCFAVAEISESDFQ-EWR 623
+I + L+ + K +I +E A+EGLRT+C A + + + EW
Sbjct: 606 IILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEW- 664
Query: 624 AVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWI 683
++ I L + IED ++ +VP+ I+ +A I + +
Sbjct: 665 ------------------DNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRM 706
Query: 684 LTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALI 743
+TGD TA I C +L + + EG R +R E
Sbjct: 707 VTGDNINTARAIATKCGILHPGEDFLCL-EGKDFNRR-------------IRNEKG---- 748
Query: 744 IDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVT 796
+ Q +D + K + R SP K +V+ + ++QV VT
Sbjct: 749 ------------EIEQERID-KIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVT 795
Query: 797 LAIGDGANDVSMIQTAHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNR 854
GDG ND ++ A VG +GI+G + + A+ + F + +M G Y+
Sbjct: 796 ---GDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDS 851
Query: 855 VSKCILYCFYKNIVLYII 872
+SK + + N+V I+
Sbjct: 852 ISKFLQFQLTVNVVAVIV 869
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 77.0 bits (188), Expect = 1e-13
Identities = 116/498 (23%), Positives = 193/498 (38%), Gaps = 115/498 (23%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKT 457
E +G I SDKTGTLT N M + I Y VPEPE
Sbjct: 464 ETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPE------------------- 504
Query: 458 FSDSSLLENLQNNHPTA-PIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAK 516
++ N+ + T + C + + + PE+EG + + E AL+
Sbjct: 505 ----AIPPNILSYLVTGISVNCAYTSKILP-----PEKEGG-LPRHVGNKTECALLGLLL 554
Query: 517 QLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADT 576
L + + + + +E Y+ V F S RK MS +++ G R++ KGA
Sbjct: 555 DLKRDYQD------VRNEIPEEALYK---VYTFNSVRKSMSTVLKNSDGSYRIFSKGASE 605
Query: 577 VIYDR----LAETSKYK--------EITLKHLEQFATEGLRTLCFAVAEISESDFQ-EWR 623
+I + L+ + K +I +E A+EGLRT+C A + + + EW
Sbjct: 606 IILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEW- 664
Query: 624 AVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWI 683
++ I L + IED ++ +VP+ I+ +A I + +
Sbjct: 665 ------------------DNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRM 706
Query: 684 LTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALI 743
+TGD TA I C +L + + EG R +R E
Sbjct: 707 VTGDNINTARAIATKCGILHPGEDFLCL-EGKDFNRR-------------IRNEKG---- 748
Query: 744 IDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVT 796
+ Q +D + K + R SP K +V+ + ++QV VT
Sbjct: 749 ------------EIEQERID-KIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVT 795
Query: 797 LAIGDGANDVSMIQTAHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNR 854
GDG ND ++ A VG +GI+G + + A+ + F + +M G Y+
Sbjct: 796 ---GDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDS 851
Query: 855 VSKCILYCFYKNIVLYII 872
+SK + + N+V I+
Sbjct: 852 ISKFLQFQLTVNVVAVIV 869
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 77.0 bits (188), Expect = 1e-13
Identities = 173/771 (22%), Positives = 305/771 (39%), Gaps = 163/771 (21%)
Query: 128 NAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPADLISLSSSEPQAMCYIETSN 187
N + +Q V+R+ + + E++ VG+IV+V G+ +PAD+ LSS C ++ S+
Sbjct: 177 NKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQG----CRVDNSS 232
Query: 188 LDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVPLGA 247
L GE+ + P +S+ + L E+ N Y
Sbjct: 233 LTGESEPQ-----PRSSEFTHENPL---------ETKNICFYSTT--------------- 263
Query: 248 DQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIA 307
L G V G+V+ TG D ++ + S + N + T + I I + I
Sbjct: 264 ---CLEGT-------VTGMVINTG-DRTIIGHIASLASGVGNEK--TPIAIEIEHFVHIV 310
Query: 308 MSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVK 367
+ S+G + S K L+ + FL II+ N +P LL T+ V
Sbjct: 311 AGVAVSIGILFFIIAVSLKYQVLD---------SIIFLIGIIVAN--VPEGLLATVTVTL 359
Query: 368 FTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIA 427
A + + + E LG I SDKTGTLT N M T+A
Sbjct: 360 SLTAKRM----------AKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM-----TVA 404
Query: 428 GVAYGHVPEPEDYGCSPDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVC 487
+ + + + + E ++Q D+ + + +SL + ++ +C
Sbjct: 405 HLWFDN----QIFVADTSEDHSNQVFDQSSRTWASLSK-----------------IITLC 443
Query: 488 HTAV--PEREGDKIIYQAASPD--EGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYEL 543
+ A P +E I+ +A D E AL++ + + ++ D + +R
Sbjct: 444 NRAEFKPGQENVPIMKKAVIGDASETALLKFS------------EVILGDVMEIRKRNRK 491
Query: 544 LNVLEFTSARKRMSVI--VRTPSGK-LRLYCKGADTVIYDRLA------ETSKYKEITLK 594
+ + F S K I + P GK + KGA I ++ + E + T K
Sbjct: 492 VAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAK 551
Query: 595 HLEQFATE----GLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKN 650
E G R L F + +F E + S + S N
Sbjct: 552 TFHTAYMELGGLGERVLGFCHLYLPADEFPE--------TYSFDIDAMNFPTS------N 597
Query: 651 LQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIV 710
L +G ++ D + VP+ + A IK+ ++TGD TA K + K++G+I
Sbjct: 598 LCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITA-------KAIAKSVGIIS 650
Query: 711 INEGSLDGTRETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKA 770
N T E ++ + + K + A ++ G LK + + ++ + +
Sbjct: 651 AN----SETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSS----EQLDEILANYQE 702
Query: 771 VICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGV--GISGNEGLQAAN 828
++ R SP QK +VE ++Q VV + GDG ND ++ A +G+ GI+G++ A N
Sbjct: 703 IVFARTSPQQKLIIVEGCQRQDAVVAVT-GDGVNDSPALKKADIGIAMGIAGSDA--AKN 759
Query: 829 SSDYSIAQFKYLKNLLMI-HGAWNYNRVSKCILYCFYKNI------VLYII 872
++D + + + + G ++ + K I Y KNI ++YII
Sbjct: 760 AADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYII 810
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
[Homo sapiens]
Length = 994
Score = 71.6 bits (174), Expect = 4e-12
Identities = 119/515 (23%), Positives = 198/515 (38%), Gaps = 112/515 (21%)
Query: 389 AMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDEWQ 448
A+ R+ E LG I SDKTGTLT N M K I G + ++ +
Sbjct: 331 AIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSIT----- 385
Query: 449 NSQFGDEKTFSDSSLLENLQNNHPTAP----IICEFLTMMAVCHTAVPEREGDKIIYQ-A 503
S + E E L+N+ P P + E T+ A+C+ + + K +Y+
Sbjct: 386 GSTYAPEG--------EVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYEKV 437
Query: 504 ASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELLN-----------VLEFTSA 552
E AL +++N T + SL + ER N LEF+
Sbjct: 438 GEATETALTTLVEKMNVFNTD-------VRSLSKVERANACNSVIRQLMKKEFTLEFSRD 490
Query: 553 RKRMSVIV------RTPSGKLRLYCKGADTVIYD----------RLAETSKYKEITLKHL 596
RK MSV R G +++ KGA + D R+ T KE + +
Sbjct: 491 RKSMSVYCSPAKSSRAAVGN-KMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVKEKIMAVI 549
Query: 597 EQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELI--EKNLQLL 654
+++ T C A+A T + + L++S + E +L +
Sbjct: 550 KEWGTGRDTLRCLALA---------------TRDTPPKREEMVLDDSARFLEYETDLTFV 594
Query: 655 GATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEG 714
G + D + +V +I+ A I++ ++TGD + TAI I C + +G+ NE
Sbjct: 595 GVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAI---C----RRIGIFGENEE 647
Query: 715 SLDGTRETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVIC- 773
D R R L A ++E +C+ C
Sbjct: 648 VAD--RAYTGREFDDLPLAEQRE-----------------------------ACRRACCF 676
Query: 774 CRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYS 833
RV P KS++VE ++ + +T GDG ND ++ A +G+ + G+ A +S+
Sbjct: 677 ARVEPSHKSKIVEYLQSYDE-ITAMTGDGVNDAPALKKAEIGIAM-GSGTAVAKTASEMV 734
Query: 834 IAQFKYLKNLLMI-HGAWNYNRVSKCILYCFYKNI 867
+A + + + G YN + + I Y N+
Sbjct: 735 LADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNV 769
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,094,345
Number of Sequences: 37866
Number of extensions: 1681739
Number of successful extensions: 4046
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 3714
Number of HSP's gapped (non-prelim): 179
length of query: 1164
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1051
effective length of database: 13,968,660
effective search space: 14681061660
effective search space used: 14681061660
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.