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Search of human proteins with 178557736
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|178557736 microtubule-associated protein tau isoform 5 [Homo
sapiens]
(412 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|178557736 microtubule-associated protein tau isoform 5 [Homo ... 830 0.0
gi|6754638 microtubule-associated protein tau isoform 2 [Homo sa... 814 0.0
gi|8400711 microtubule-associated protein tau isoform 3 [Homo sa... 757 0.0
gi|8400715 microtubule-associated protein tau isoform 4 [Homo sa... 668 0.0
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s... 608 e-174
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 597 e-171
gi|87578255 microtubule-associated protein 2 isoform 4 [Homo sap... 325 6e-89
gi|87578394 microtubule-associated protein 2 isoform 5 [Homo sap... 322 4e-88
gi|87578392 microtubule-associated protein 2 isoform 2 [Homo sap... 254 8e-68
gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sap... 251 6e-67
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa... 223 3e-58
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap... 185 6e-47
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap... 185 6e-47
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa... 140 3e-33
gi|150170670 piccolo isoform 2 [Homo sapiens] 58 1e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 58 1e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 55 9e-08
gi|54860079 nadrin isoform 1 [Homo sapiens] 50 3e-06
gi|54860105 nadrin isoform 2 [Homo sapiens] 50 3e-06
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens] 50 4e-06
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 50 4e-06
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 49 6e-06
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 49 6e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 49 1e-05
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 48 1e-05
gi|55741677 SET domain containing 1A [Homo sapiens] 48 1e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 48 2e-05
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 47 2e-05
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 47 3e-05
gi|47132519 Ras association and pleckstrin homology domains 1 is... 47 3e-05
>gi|178557736 microtubule-associated protein tau isoform 5 [Homo
sapiens]
Length = 412
Score = 830 bits (2143), Expect = 0.0
Identities = 412/412 (100%), Positives = 412/412 (100%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT 120
SETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT
Sbjct: 61 SETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT 120
Query: 121 KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR 180
KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR
Sbjct: 121 KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR 180
Query: 181 SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ 240
SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ
Sbjct: 181 SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ 240
Query: 241 PGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIH 300
PGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIH
Sbjct: 241 PGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIH 300
Query: 301 HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG 360
HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG
Sbjct: 301 HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG 360
Query: 361 AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 361 AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
>gi|6754638 microtubule-associated protein tau isoform 2 [Homo
sapiens]
Length = 441
Score = 814 bits (2103), Expect = 0.0
Identities = 412/441 (93%), Positives = 412/441 (93%), Gaps = 29/441 (6%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAE-----------------------------AEEAGIGDTPSLEDEAAG 91
SETSDAKSTPTAE AEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 92 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK 151
HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
Sbjct: 121 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK 180
Query: 152 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 211
TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
Sbjct: 181 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 240
Query: 212 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV 271
SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV
Sbjct: 241 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV 300
Query: 272 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI 331
PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
Sbjct: 301 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI 360
Query: 332 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV 391
THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
Sbjct: 361 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV 420
Query: 392 DSPQLATLADEVSASLAKQGL 412
DSPQLATLADEVSASLAKQGL
Sbjct: 421 DSPQLATLADEVSASLAKQGL 441
>gi|8400711 microtubule-associated protein tau isoform 3 [Homo
sapiens]
Length = 383
Score = 757 bits (1954), Expect = 0.0
Identities = 383/412 (92%), Positives = 383/412 (92%), Gaps = 29/412 (7%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK---------------- 44
Query: 61 SETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT 120
AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT
Sbjct: 45 -------------AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT 91
Query: 121 KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR 180
KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR
Sbjct: 92 KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR 151
Query: 181 SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ 240
SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ
Sbjct: 152 SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ 211
Query: 241 PGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIH 300
PGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIH
Sbjct: 212 PGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIH 271
Query: 301 HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG 360
HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG
Sbjct: 272 HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG 331
Query: 361 AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 332 AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 383
>gi|8400715 microtubule-associated protein tau isoform 4 [Homo
sapiens]
Length = 352
Score = 668 bits (1723), Expect = 0.0
Identities = 346/412 (83%), Positives = 348/412 (84%), Gaps = 60/412 (14%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK---------------- 44
Query: 61 SETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT 120
AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT
Sbjct: 45 -------------AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKT 91
Query: 121 KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR 180
KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR
Sbjct: 92 KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR 151
Query: 181 SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ 240
SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVK
Sbjct: 152 SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVK------------ 199
Query: 241 PGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIH 300
SK GS +N+KH PGGG VQIVYKPVDLSKVTSKCGSLGNIH
Sbjct: 200 -------------------SKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIH 240
Query: 301 HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG 360
HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG
Sbjct: 241 HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHG 300
Query: 361 AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 301 AEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 352
>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
sapiens]
Length = 758
Score = 608 bits (1569), Expect = e-174
Identities = 304/331 (91%), Positives = 311/331 (93%)
Query: 82 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 141
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
Query: 142 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 201
IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR
Sbjct: 488 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 547
Query: 202 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 261
TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK
Sbjct: 548 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 607
Query: 262 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 321
CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV
Sbjct: 608 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 667
Query: 322 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 381
QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN
Sbjct: 668 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 727
Query: 382 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
VSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 728 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
Score = 194 bits (494), Expect = 9e-50
Identities = 130/315 (41%), Positives = 150/315 (47%), Gaps = 112/315 (35%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAE-----------------------------AEEAGIGDTPSLEDEAAG 91
SETSDAKSTPTAE AEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 92 HVTQ--------------------------------------ARMVSKSKDGTGSDDKKA 113
HVTQ R ++ GTG +D +
Sbjct: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
Query: 114 -----------------------KGADGKTKIATPRGAAPPGQKGQANATR-----IPAK 145
KGA GK + PG K + + R P
Sbjct: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKER---------PGSKEEVDEDRDVDESSPQD 231
Query: 146 TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK-KVAVVRTPP 204
+PP+ +P G PP++ R S PG P ++P P K + + P
Sbjct: 232 SPPSKASPAQDGRPPQTAAREATSIPGFPA-------EGAIPLPVDFLSKVSTEIPASEP 284
Query: 205 KSPSSAKSRLQTAPV 219
PS +++ Q AP+
Sbjct: 285 DGPSVGRAKGQDAPL 299
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 597 bits (1540), Expect = e-171
Identities = 304/349 (87%), Positives = 311/349 (89%), Gaps = 18/349 (5%)
Query: 82 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 141
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
Query: 142 IPAKTPPAPKTPPSS------------------GEPPKSGDRSGYSSPGSPGTPGSRSRT 183
IPAKTPPAPKTPPSS GEPPKSGDRSGYSSPGSPGTPGSRSRT
Sbjct: 488 IPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGTPGSRSRT 547
Query: 184 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 243
PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG
Sbjct: 548 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 607
Query: 244 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 303
GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP
Sbjct: 608 GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 667
Query: 304 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 363
GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI
Sbjct: 668 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEI 727
Query: 364 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 728 VYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
Score = 194 bits (494), Expect = 9e-50
Identities = 130/315 (41%), Positives = 150/315 (47%), Gaps = 112/315 (35%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAE-----------------------------AEEAGIGDTPSLEDEAAG 91
SETSDAKSTPTAE AEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 92 HVTQ--------------------------------------ARMVSKSKDGTGSDDKKA 113
HVTQ R ++ GTG +D +
Sbjct: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
Query: 114 -----------------------KGADGKTKIATPRGAAPPGQKGQANATR-----IPAK 145
KGA GK + PG K + + R P
Sbjct: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKER---------PGSKEEVDEDRDVDESSPQD 231
Query: 146 TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK-KVAVVRTPP 204
+PP+ +P G PP++ R S PG P ++P P K + + P
Sbjct: 232 SPPSKASPAQDGRPPQTAAREATSIPGFPA-------EGAIPLPVDFLSKVSTEIPASEP 284
Query: 205 KSPSSAKSRLQTAPV 219
PS +++ Q AP+
Sbjct: 285 DGPSVGRAKGQDAPL 299
>gi|87578255 microtubule-associated protein 2 isoform 4 [Homo
sapiens]
Length = 502
Score = 325 bits (832), Expect = 6e-89
Identities = 197/411 (47%), Positives = 259/411 (63%), Gaps = 40/411 (9%)
Query: 25 DQGGYTMHQDQEG------DTDAGLKESPLQTPTEDGS----EEPGSETSDAKSTPTAEA 74
+Q H+DQ + A L SP +P + + E G E++ A S
Sbjct: 109 EQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAK 168
Query: 75 EEAGIGDTPSLEDEAA-----GHVTQARMVSKSKDGTG-SDDKKAKGADGKTKIATPRGA 128
++ G T S E ++ + R VS +D S + + +T + P
Sbjct: 169 DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRR 228
Query: 129 APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS--PGSPGTPGSRSRTPSL 186
A G+ G + T P T P TPPS YSS PG+PGTP S RTP
Sbjct: 229 A--GKSGTSTPTT-PGSTAITPGTPPS------------YSSRTPGTPGTP-SYPRTPHT 272
Query: 187 PTPPTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 241
P P KKVA++RTPPKSP++ K +L+ P+PDLKNVKSKIGST+N+K+QP
Sbjct: 273 PGTPKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQP 331
Query: 242 GGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHH 301
GG+V+I+NKK+D S VQS+CGSKDNIKH GGG+VQIV K +DLS VTSKCGSL NI H
Sbjct: 332 KGGQVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRH 391
Query: 302 KPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGA 361
+PGGG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGA
Sbjct: 392 RPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGA 451
Query: 362 EIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
EI+ +SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 452 EIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 502
>gi|87578394 microtubule-associated protein 2 isoform 5 [Homo
sapiens]
Length = 559
Score = 322 bits (825), Expect = 4e-88
Identities = 187/391 (47%), Positives = 249/391 (63%), Gaps = 40/391 (10%)
Query: 51 PTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDD 110
P GS + +S ST + A D+ ++ +AG T SKS G+ D
Sbjct: 180 PALQGSTKSPRYSSACPST----TKRATFSDSLLIQPTSAGS-TDRLPYSKS----GNKD 230
Query: 111 KKAKGADGKTKIATPRGAAPP--GQKGQ------------ANATRIPAKTPP-------- 148
K + ++ + P PP G G +++ R ++ P
Sbjct: 231 GVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSG 290
Query: 149 --APKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTR-----EPKKVAVVR 201
P TP S+ P + +PG+PGTP S RTP P P KKVA++R
Sbjct: 291 TSTPTTPGSTAITPGTPPSYSSRTPGTPGTP-SYPRTPHTPGTPKSAILVPSEKKVAIIR 349
Query: 202 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 261
TPPKSP++ K +L+ P+PDLKNVKSKIGST+N+K+QP GG+V+I+NKK+D S VQS+
Sbjct: 350 TPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKIDFSKVQSR 408
Query: 262 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 321
CGSKDNIKH GGG+VQIV K +DLS VTSKCGSL NI H+PGGG+V+++S KLDFK++
Sbjct: 409 CGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKA 468
Query: 322 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 381
Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAEI+ +SP S SPR LSN
Sbjct: 469 QAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSN 528
Query: 382 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
VSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 529 VSSSGSINLLESPQLATLAEDVTAALAKQGL 559
>gi|87578392 microtubule-associated protein 2 isoform 2 [Homo
sapiens]
Length = 471
Score = 254 bits (650), Expect = 8e-68
Identities = 173/411 (42%), Positives = 228/411 (55%), Gaps = 71/411 (17%)
Query: 25 DQGGYTMHQDQEG------DTDAGLKESPLQTPTEDGS----EEPGSETSDAKSTPTAEA 74
+Q H+DQ + A L SP +P + + E G E++ A S
Sbjct: 109 EQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAK 168
Query: 75 EEAGIGDTPSLEDEAA-----GHVTQARMVSKSKDGTG-SDDKKAKGADGKTKIATPRGA 128
++ G T S E ++ + R VS +D S + + +T + P
Sbjct: 169 DKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRR 228
Query: 129 APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS--PGSPGTPGSRSRTPSL 186
A G+ G + T P T P TPPS YSS PG+PGTP S RTP
Sbjct: 229 A--GKSGTSTPTT-PGSTAITPGTPPS------------YSSRTPGTPGTP-SYPRTPHT 272
Query: 187 PTPPTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 241
P P KKVA++RTPPKSP++ K +L+ P+PDLK
Sbjct: 273 PGTPKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLK---------------- 315
Query: 242 GGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHH 301
NV+SK GS DNIK+ P GG VQIV K +DLS VTSKCGSL NI H
Sbjct: 316 ---------------NVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRH 360
Query: 302 KPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGA 361
+PGGG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGA
Sbjct: 361 RPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGA 420
Query: 362 EIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
EI+ +SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 421 EIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 471
>gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sapiens]
Length = 1827
Score = 251 bits (642), Expect = 6e-67
Identities = 147/288 (51%), Positives = 184/288 (63%), Gaps = 53/288 (18%)
Query: 132 GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS--PGSPGTPGSRSRTPSLPTP 189
G+ G + T P T P TPPS YSS PG+PGTP S RTP P
Sbjct: 1586 GKSGTSTPTT-PGSTAITPGTPPS------------YSSRTPGTPGTP-SYPRTPHTPGT 1631
Query: 190 PTR-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG 244
P KKVA++RTPPKSP++ K +L+ P+PDLK
Sbjct: 1632 PKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLK------------------- 1671
Query: 245 KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPG 304
NV+SK GS DNIK+ P GG VQIV K +DLS VTSKCGSL NI H+PG
Sbjct: 1672 ------------NVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPG 1719
Query: 305 GGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIV 364
GG+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAEI+
Sbjct: 1720 GGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEII 1779
Query: 365 YKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
+SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 1780 TQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 1827
>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
sapiens]
Length = 1135
Score = 223 bits (567), Expect = 3e-58
Identities = 145/376 (38%), Positives = 191/376 (50%), Gaps = 71/376 (18%)
Query: 57 EEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGA 116
+ P ++ P+ + + I D + E A+ + S+S +K
Sbjct: 754 KRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSG---------SKST 804
Query: 117 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGS 173
K T A G ++ +T +P K P A KT E K +S S P S
Sbjct: 805 QTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863
Query: 174 PGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK--------SRL 214
T + T T P V TP K P+SAK SRL
Sbjct: 864 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923
Query: 215 QTAPVPMPDLKNVKSKIGSTENLKHQPGGG------------------------------ 244
T PDLKNV+SK+GSTEN+KHQPGGG
Sbjct: 924 ATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIA 982
Query: 245 --------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 296
KVQI++KK+ S++QSKCGSKDNIKHVPGGG+VQI K VD+SKV+SKCGS
Sbjct: 983 SAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSK 1042
Query: 297 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 356
NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG KIET++LTFR NA+A+
Sbjct: 1043 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKIETYRLTFRANARAR 1102
Query: 357 TDHGAEIVYKSPVVSG 372
TDHGA+IV + P G
Sbjct: 1103 TDHGADIVSRPPHFPG 1118
Score = 50.4 bits (119), Expect = 3e-06
Identities = 94/400 (23%), Positives = 141/400 (35%), Gaps = 58/400 (14%)
Query: 26 QGGYTMHQDQEGDTDAGLKESP---LQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDT 82
Q G + E D G +P + T G+ + S ++ S E
Sbjct: 598 QKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQ 657
Query: 83 PS-LEDEAAGHVTQARMVSKSKDGTGSD------DKKAKGADGKTK-IATPRGAAPPGQK 134
PS L E +G + + GTG+D + + KTK +AT + A K
Sbjct: 658 PSELSSETSG-IARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSK 716
Query: 135 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 194
+ T +P + PAP T + P S SG P P S PS+ +P
Sbjct: 717 AKTQPTSLPKQ--PAPTTIGGLNKKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKP 773
Query: 195 KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVK--------SKIGSTENLKHQPG---- 242
K +A + P K S +K +AP K+ + + + ST P
Sbjct: 774 KPIADAKAPEKRASPSKP--ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLP 831
Query: 243 --------GGKVQIINK------KLDLSNVQSKCGSKDNIKHVPGG--GSVQIVYKPVDL 286
GK + K DLS +S S G + +V V
Sbjct: 832 KKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKA 891
Query: 287 SKVTSKCGSLGNIHHKPGGGQVEVKSEKL----------DFKDRVQSKIGSLDNITHVPG 336
+ + S+ + I KP + + +L D K+ V+SK+GS +NI H PG
Sbjct: 892 TPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPG 950
Query: 337 GGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSP 376
GG K+E K T K + A P+ S P
Sbjct: 951 GGRAKVE--KKTEAAATTRKPESNAVTKTAGPIASAQKQP 988
Score = 33.5 bits (75), Expect = 0.36
Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 11/151 (7%)
Query: 81 DTPSLEDEAAGHVTQARM-VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANA 139
D P L + A V M +++++ G D D A +P G
Sbjct: 575 DVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634
Query: 140 TRIPAKTPPA-----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTP 189
+PA+ + P +S S + SG + P G P GT + P+ P
Sbjct: 635 CSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP 694
Query: 190 PTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 220
P+ E K + T P S++K++ Q +P
Sbjct: 695 PSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725
>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
sapiens]
Length = 887
Score = 185 bits (470), Expect = 6e-47
Identities = 127/347 (36%), Positives = 167/347 (48%), Gaps = 71/347 (20%)
Query: 57 EEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGA 116
+ P ++ P+ + + I D + E A+ + S+S +K
Sbjct: 489 KRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSG---------SKST 539
Query: 117 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGS 173
K T A G ++ +T +P K P A KT E K +S S P S
Sbjct: 540 QTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598
Query: 174 PGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK--------SRL 214
T + T T P V TP K P+SAK SRL
Sbjct: 599 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 658
Query: 215 QTAPVPMPDLKNVKSKIGSTENLKHQPGGG------------------------------ 244
T PDLKNV+SK+GSTEN+KHQPGGG
Sbjct: 659 ATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIA 717
Query: 245 --------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 296
KVQI++KK+ S++QSKCGSKDNIKHVPGGG+VQI K VD+SKV+SKCGS
Sbjct: 718 SAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSK 777
Query: 297 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 343
NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E
Sbjct: 778 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 824
Score = 49.7 bits (117), Expect = 5e-06
Identities = 78/317 (24%), Positives = 115/317 (36%), Gaps = 53/317 (16%)
Query: 105 GTGSD------DKKAKGADGKTK-IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG 157
GTG+D + + KTK +AT + A K + T +P + PAP T
Sbjct: 415 GTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQ--PAPTTIGGLN 472
Query: 158 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA 217
+ P S SG P P S PS+ +PK +A + P K S +K +A
Sbjct: 473 KKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKP--ASA 529
Query: 218 PVPMPDLKNVK--------SKIGSTENLKHQPG------------GGKVQIINK------ 251
P K+ + + + ST P GK + K
Sbjct: 530 PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSV 589
Query: 252 KLDLSNVQSKCGSKDNIKHVPGG--GSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVE 309
DLS +S S G + +V V + + S+ + I KP +
Sbjct: 590 PADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 649
Query: 310 VKSEKL----------DFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDH 359
+ +L D K+ V+SK+GS +NI H PGGG K+E K T K +
Sbjct: 650 STTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPGGGRAKVE--KKTEAAATTRKPES 706
Query: 360 GAEIVYKSPVVSGDTSP 376
A P+ S P
Sbjct: 707 NAVTKTAGPIASAQKQP 723
Score = 43.9 bits (102), Expect = 3e-04
Identities = 46/169 (27%), Positives = 70/169 (41%), Gaps = 22/169 (13%)
Query: 57 EEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGA 116
E P SE +D TA G+ P +D+ T +M KS+ T + KK
Sbjct: 309 EAPPSEVADTLVIMTASK---GVR-LPEPKDKILE--TPQKMTEKSESKTPGEGKK---- 358
Query: 117 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP--GSP 174
+ K+++A P KG T+ TP PK+ E K +G + P G P
Sbjct: 359 EDKSRMAEP-------MKGYMRPTKSRGLTPLLPKSTIQEQERHKQLKSAGIARPEEGRP 411
Query: 175 ---GTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 220
GT + P+ PP+ E K + T P S++K++ Q +P
Sbjct: 412 VVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 460
>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sapiens]
Length = 1152
Score = 185 bits (470), Expect = 6e-47
Identities = 127/347 (36%), Positives = 167/347 (48%), Gaps = 71/347 (20%)
Query: 57 EEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGA 116
+ P ++ P+ + + I D + E A+ + S+S +K
Sbjct: 754 KRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSG---------SKST 804
Query: 117 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGS 173
K T A G ++ +T +P K P A KT E K +S S P S
Sbjct: 805 QTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863
Query: 174 PGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK--------SRL 214
T + T T P V TP K P+SAK SRL
Sbjct: 864 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923
Query: 215 QTAPVPMPDLKNVKSKIGSTENLKHQPGGG------------------------------ 244
T PDLKNV+SK+GSTEN+KHQPGGG
Sbjct: 924 ATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIA 982
Query: 245 --------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 296
KVQI++KK+ S++QSKCGSKDNIKHVPGGG+VQI K VD+SKV+SKCGS
Sbjct: 983 SAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSK 1042
Query: 297 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 343
NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E
Sbjct: 1043 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
Score = 50.4 bits (119), Expect = 3e-06
Identities = 94/400 (23%), Positives = 141/400 (35%), Gaps = 58/400 (14%)
Query: 26 QGGYTMHQDQEGDTDAGLKESP---LQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDT 82
Q G + E D G +P + T G+ + S ++ S E
Sbjct: 598 QKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQ 657
Query: 83 PS-LEDEAAGHVTQARMVSKSKDGTGSD------DKKAKGADGKTK-IATPRGAAPPGQK 134
PS L E +G + + GTG+D + + KTK +AT + A K
Sbjct: 658 PSELSSETSG-IARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSK 716
Query: 135 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 194
+ T +P + PAP T + P S SG P P S PS+ +P
Sbjct: 717 AKTQPTSLPKQ--PAPTTIGGLNKKPMSL-ASGLVPAAPPKRPAVASARPSILPSKDVKP 773
Query: 195 KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVK--------SKIGSTENLKHQPG---- 242
K +A + P K S +K +AP K+ + + + ST P
Sbjct: 774 KPIADAKAPEKRASPSKP--ASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLP 831
Query: 243 --------GGKVQIINK------KLDLSNVQSKCGSKDNIKHVPGG--GSVQIVYKPVDL 286
GK + K DLS +S S G + +V V
Sbjct: 832 KKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKA 891
Query: 287 SKVTSKCGSLGNIHHKPGGGQVEVKSEKL----------DFKDRVQSKIGSLDNITHVPG 336
+ + S+ + I KP + + +L D K+ V+SK+GS +NI H PG
Sbjct: 892 TPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKN-VRSKVGSTENIKHQPG 950
Query: 337 GGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSP 376
GG K+E K T K + A P+ S P
Sbjct: 951 GGRAKVE--KKTEAAATTRKPESNAVTKTAGPIASAQKQP 988
Score = 33.5 bits (75), Expect = 0.36
Identities = 35/151 (23%), Positives = 57/151 (37%), Gaps = 11/151 (7%)
Query: 81 DTPSLEDEAAGHVTQARM-VSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANA 139
D P L + A V M +++++ G D D A +P G
Sbjct: 575 DVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKK 634
Query: 140 TRIPAKTPPA-----PKTPPSSGEPPKSGDRSGYSSP--GSP---GTPGSRSRTPSLPTP 189
+PA+ + P +S S + SG + P G P GT + P+ P
Sbjct: 635 CSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELP 694
Query: 190 PTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 220
P+ E K + T P S++K++ Q +P
Sbjct: 695 PSPEKKTKPLATTQPAKTSTSKAKTQPTSLP 725
>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
sapiens]
Length = 817
Score = 140 bits (352), Expect = 3e-33
Identities = 100/291 (34%), Positives = 136/291 (46%), Gaps = 28/291 (9%)
Query: 57 EEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGA 116
+ P ++ P+ + + I D + E A+ + S+S +K
Sbjct: 489 KRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSG---------SKST 539
Query: 117 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGS 173
K T A G ++ +T +P K P A KT E K +S S P S
Sbjct: 540 QTVAKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKS 598
Query: 174 PGTPGSRSRTPSLPTPPTREPKKVAVVRTP-PKSPSSAKSRLQTAPVPMPDLKNVKSKIG 232
T + T T P V TP P PS+ P D K +K
Sbjct: 599 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTT---------PFIDKKPTSAKPS 649
Query: 233 STENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSK 292
ST P ++ DL NV+SK GS +NIKH PGGG VQI K VD+SKV+SK
Sbjct: 650 STT-----PRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRVQIQNKKVDISKVSSK 704
Query: 293 CGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 343
CGS NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E
Sbjct: 705 CGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 755
Score = 95.9 bits (237), Expect = 6e-20
Identities = 102/369 (27%), Positives = 153/369 (41%), Gaps = 33/369 (8%)
Query: 4 PRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGD-TDAGLKESPLQTPTEDGSEEPGSE 62
P+ + E H G + + G + D T KE P P+ + +P +
Sbjct: 385 PKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELP---PSPEKKTKPLAT 441
Query: 63 TSDAK-STPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTK 121
T AK ST A+ + + P+ G + + M S + K+ A +
Sbjct: 442 TQPAKTSTSKAKTQPTSLPKQPA--PTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPS 499
Query: 122 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 181
I + P K A+A + P K A + P+S +SG +S + + S
Sbjct: 500 ILPSKDVKP---KPIADA-KAPEKR--ASPSKPASAPASRSGSKSTQTVAKTTTAAAVAS 553
Query: 182 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQ- 240
PS +P T PKK ++T K K ++ P DL KS ST ++K
Sbjct: 554 TGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPA---DLSRPKST--STSSMKKTT 608
Query: 241 ------PGGGKVQIINKKLDLSN-------VQSKCGSKDNIKHVPGGGSVQIVYKPVDLS 287
P G V K + + + K S P + DL
Sbjct: 609 TLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLK 668
Query: 288 KVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKL 347
V SK GS NI H+PGGG+V+++++K+D +V SK GS NI H PGGG+ KIE+ KL
Sbjct: 669 NVRSKVGSTENIKHQPGGGRVQIQNKKVDIS-KVSSKCGSKANIKHKPGGGDVKIESQKL 727
Query: 348 TFRENAKAK 356
F+E A+AK
Sbjct: 728 NFKEKAQAK 736
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/199 (27%), Positives = 74/199 (37%), Gaps = 16/199 (8%)
Query: 47 PLQTPTED-GSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDG 105
P + P + GSE+P SE + P A A+ G+G TP+ + A TQ K
Sbjct: 368 PAKPPAQQTGSEKPSSE----QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Query: 106 TGSDDKKAKGADGKTKIATPR---GAAPPGQKG-------QANATRIPAKTPPAPKTPPS 155
AK A G TK + G P Q G Q T+ P++ P K PP
Sbjct: 424 QPGLQSPAK-APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
Query: 156 SGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQ 215
P K + S+ PGS P P P P++ + P + P SAK Q
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ 542
Query: 216 TAPVPMPDLKNVKSKIGST 234
P + + T
Sbjct: 543 QPSPAKPSAQQSTKPVSQT 561
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 18/106 (16%)
Query: 128 AAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 187
A PG Q+ P K PAP PP+S PPKS +G + P P+
Sbjct: 949 AGQPGPHSQSGPGA-PMKQAPAPSQPPTSQGPPKS---TGQAPP-----------APAKS 993
Query: 188 TPPTREPKKVAVVRTPPK---SPSSAKSRLQTAPVPMPDLKNVKSK 230
P +E K A + PK +P+ ++ + P P+ D K++ ++
Sbjct: 994 IPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039
Score = 36.6 bits (83), Expect = 0.043
Identities = 52/222 (23%), Positives = 80/222 (36%), Gaps = 24/222 (10%)
Query: 34 DQEGDTDAGLKESPLQTPT---EDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAA 90
D D++A +E+ + E G E + + P ++ G G P +D
Sbjct: 177 DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTP 236
Query: 91 GHVT--QARMVSKSKDGTGS--DDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKT 146
++ Q + GTG K+ R A+ P K QA+ R +
Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTK-QADIVRGESVK 295
Query: 147 P--PAPKTPP----SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVV 200
P P+P PP + G+PP S PG P S L P ++P V
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPS---GLTKPLAQQP---GTV 349
Query: 201 RTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 242
+ P + P + K Q P+ K + GS + QPG
Sbjct: 350 KPPVQPPGTTKPPAQ----PLGPAKPPAQQTGSEKPSSEQPG 387
Score = 34.7 bits (78), Expect = 0.16
Identities = 48/213 (22%), Positives = 67/213 (31%), Gaps = 35/213 (16%)
Query: 93 VTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIP---AKTPP- 148
VT VSKS K A + P PP Q P AK PP
Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725
Query: 149 -----------APKTPPSSGEPPKSGDR--------------SGYSSPGSPGTPGSR--S 181
P P + P + D+ S S+ P P S+ S
Sbjct: 726 ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785
Query: 182 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 241
+ TPP + PP + + P P D K + S+E+
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES----K 841
Query: 242 GGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGG 274
G +V + KK + Q+K K + K +P G
Sbjct: 842 GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG 874
Score = 32.7 bits (73), Expect = 0.62
Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 5/105 (4%)
Query: 142 IPAKTPPAPKTPP--SSGEPPKSGDRSGYSSPGSPGTPG---SRSRTPSLPTPPTREPKK 196
+P+ P KT P ++ KS + +SP P S++ P P P ++P
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 197 VAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 241
K P A S + AP P + + + K ++ QP
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP 757
Score = 32.7 bits (73), Expect = 0.62
Identities = 51/184 (27%), Positives = 69/184 (37%), Gaps = 14/184 (7%)
Query: 52 TEDGSEEPGSETSDAKSTPTAE----AEEAGIGDTPSLEDEAAGHVTQARMVSK-SKDGT 106
TE +P S+ S AE E G TPS+ V + +S K
Sbjct: 3502 TEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYK 3561
Query: 107 GSDDKKAKGADGKTKIATPRGA-APPGQKGQANATRIPAKTP-PAPKTPPSSGEPPKSGD 164
G AD T+ A +PP K + I + A T + PPKS
Sbjct: 3562 GGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKS-P 3620
Query: 165 RSGYS--SPGSPGTPGSRSRTP-SLPTPPTREPKKVA---VVRTPPKSPSSAKSRLQTAP 218
+ YS SP SPG + P P P P+KV + + PP SP +AK ++
Sbjct: 3621 KVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMS 3680
Query: 219 VPMP 222
P P
Sbjct: 3681 DPKP 3684
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/199 (27%), Positives = 74/199 (37%), Gaps = 16/199 (8%)
Query: 47 PLQTPTED-GSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDG 105
P + P + GSE+P SE + P A A+ G+G TP+ + A TQ K
Sbjct: 368 PAKPPAQQTGSEKPSSE----QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Query: 106 TGSDDKKAKGADGKTKIATPR---GAAPPGQKG-------QANATRIPAKTPPAPKTPPS 155
AK A G TK + G P Q G Q T+ P++ P K PP
Sbjct: 424 QPGLQSPAK-APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
Query: 156 SGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQ 215
P K + S+ PGS P P P P++ + P + P SAK Q
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ 542
Query: 216 TAPVPMPDLKNVKSKIGST 234
P + + T
Sbjct: 543 QPSPAKPSAQQSTKPVSQT 561
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 18/106 (16%)
Query: 128 AAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP 187
A PG Q+ P K PAP PP+S PPKS +G + P P+
Sbjct: 949 AGQPGPHSQSGPGA-PMKQAPAPSQPPTSQGPPKS---TGQAPP-----------APAKS 993
Query: 188 TPPTREPKKVAVVRTPPK---SPSSAKSRLQTAPVPMPDLKNVKSK 230
P +E K A + PK +P+ ++ + P P+ D K++ ++
Sbjct: 994 IPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039
Score = 36.6 bits (83), Expect = 0.043
Identities = 52/222 (23%), Positives = 80/222 (36%), Gaps = 24/222 (10%)
Query: 34 DQEGDTDAGLKESPLQTPT---EDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAA 90
D D++A +E+ + E G E + + P ++ G G P +D
Sbjct: 177 DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTP 236
Query: 91 GHVT--QARMVSKSKDGTGS--DDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKT 146
++ Q + GTG K+ R A+ P K QA+ R +
Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTK-QADIVRGESVK 295
Query: 147 P--PAPKTPP----SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVV 200
P P+P PP + G+PP S PG P S L P ++P V
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPS---GLTKPLAQQP---GTV 349
Query: 201 RTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPG 242
+ P + P + K Q P+ K + GS + QPG
Sbjct: 350 KPPVQPPGTTKPPAQ----PLGPAKPPAQQTGSEKPSSEQPG 387
Score = 34.7 bits (78), Expect = 0.16
Identities = 48/213 (22%), Positives = 67/213 (31%), Gaps = 35/213 (16%)
Query: 93 VTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIP---AKTPP- 148
VT VSKS K A + P PP Q P AK PP
Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725
Query: 149 -----------APKTPPSSGEPPKSGDR--------------SGYSSPGSPGTPGSR--S 181
P P + P + D+ S S+ P P S+ S
Sbjct: 726 ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785
Query: 182 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 241
+ TPP + PP + + P P D K + S+E+
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES----K 841
Query: 242 GGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGG 274
G +V + KK + Q+K K + K +P G
Sbjct: 842 GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG 874
Score = 32.7 bits (73), Expect = 0.62
Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 5/105 (4%)
Query: 142 IPAKTPPAPKTPP--SSGEPPKSGDRSGYSSPGSPGTPG---SRSRTPSLPTPPTREPKK 196
+P+ P KT P ++ KS + +SP P S++ P P P ++P
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL 712
Query: 197 VAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 241
K P A S + AP P + + + K ++ QP
Sbjct: 713 HGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP 757
Score = 32.7 bits (73), Expect = 0.62
Identities = 51/184 (27%), Positives = 69/184 (37%), Gaps = 14/184 (7%)
Query: 52 TEDGSEEPGSETSDAKSTPTAE----AEEAGIGDTPSLEDEAAGHVTQARMVSK-SKDGT 106
TE +P S+ S AE E G TPS+ V + +S K
Sbjct: 3502 TEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYK 3561
Query: 107 GSDDKKAKGADGKTKIATPRGA-APPGQKGQANATRIPAKTP-PAPKTPPSSGEPPKSGD 164
G AD T+ A +PP K + I + A T + PPKS
Sbjct: 3562 GGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKS-P 3620
Query: 165 RSGYS--SPGSPGTPGSRSRTP-SLPTPPTREPKKVA---VVRTPPKSPSSAKSRLQTAP 218
+ YS SP SPG + P P P P+KV + + PP SP +AK ++
Sbjct: 3621 KVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMS 3680
Query: 219 VPMP 222
P P
Sbjct: 3681 DPKP 3684
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 55.5 bits (132), Expect = 9e-08
Identities = 58/209 (27%), Positives = 78/209 (37%), Gaps = 30/209 (14%)
Query: 42 GLKESPLQT-----PTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQA 96
G K+SP T P+ G+ P + T + T +E +L G T A
Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904
Query: 97 RMVSKSKDGTGSDDKKAKGADGKTKIA---------TPRGAAPPGQKGQAN------ATR 141
+ + T S KKA+ I TP A PP KG A
Sbjct: 905 PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT 964
Query: 142 IPAKTPPAPKTPPSSGEP---PKSGDRSGYSSPGSPGTPGSR-SRTPSLPTPPTREPKKV 197
PA TPP+PK P++ P P + S G P TP + + TP TPP+ +
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 198 AV-----VRTPP-KSPSSAKSRLQTAPVP 220
A TPP +P S K P+P
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLP 1053
Score = 53.1 bits (126), Expect = 4e-07
Identities = 61/210 (29%), Positives = 76/210 (36%), Gaps = 43/210 (20%)
Query: 46 SPLQTPTEDGSEEP----GSETSDAKSTPTAEAEEAGIGDTPSLEDEAA-----GHVTQA 96
SP PT + P G T K PT A PSL+ A G A
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA-----ATPPSLKGGLATPPHKGAPNPA 1290
Query: 97 RMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQAN------ATRIPAKTPPAP 150
+ S G G KGA TP A PP KG A PA TPP+P
Sbjct: 1291 VVTPPSPKG-GPATSPPKGAP------TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
Query: 151 K--------TPPSSGEPPKSGDRSGYSSP-------GSPG-TPGSRSRTPSLPTPPTREP 194
K TP S G P + G + P G P TP S R P++P+P
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403
Query: 195 KKVAVVRTPPKSPSSAKSRLQTAPVPMPDL 224
+ +P K+P++ +R A DL
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDL 1433
Score = 51.2 bits (121), Expect = 2e-06
Identities = 47/187 (25%), Positives = 62/187 (33%), Gaps = 14/187 (7%)
Query: 46 SPLQTPTEDGSEEP----GSETSDAKSTPTAEA-EEAGIGDTPSLEDEAAGHVTQARMVS 100
SP PT + P G T K PT A +P+ G T
Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
Query: 101 KSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPP 160
S G+ + KGA P P A PA TPP+PK P++ P
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100
Query: 161 KS---------GDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK 211
+ + G ++P G P + + TP P P TP +P S K
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160
Query: 212 SRLQTAP 218
L T P
Sbjct: 1161 GGLATPP 1167
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/229 (24%), Positives = 74/229 (32%), Gaps = 25/229 (10%)
Query: 30 TMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTP-----TAEAEEAGIGDTPS 84
T+ + G LK +P S + G T K P T + + G+ P
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP- 1121
Query: 85 LEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGA-APPGQKGQANATRIP 143
T A K G + K +P+G A P KG A P
Sbjct: 1122 ---HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG---APTTP 1175
Query: 144 AKTPPAPK----TPPSSGEPPKSG-----DRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 194
A TPP+PK TP G P + G ++P G P + + TP P P
Sbjct: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1235
Query: 195 KKVAVVRTPPKSPSSAKSRLQTAP---VPMPDLKNVKSKIGSTENLKHQ 240
TP +P S K T P P P S G H+
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Score = 49.7 bits (117), Expect = 5e-06
Identities = 55/194 (28%), Positives = 65/194 (33%), Gaps = 28/194 (14%)
Query: 46 SPLQTPTEDGSEEP----GSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSK 101
SP PT + P G T K PT A G T
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994
Query: 102 SKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIP-------AKTPPAPKTPP 154
S G G KGA TP PP KG AT P A TPP+PK P
Sbjct: 995 SPKG-GPATPSPKGAP------TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047
Query: 155 SSGEPPKSGDRSGY----SSPGSPGTPGSR-SRTPSLPTPPTRE-----PKKVAVVRTPP 204
++ PK + S G P TP + + TP TPP+ + P P
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA 1107
Query: 205 KSPSSAKSRLQTAP 218
+P S K L T P
Sbjct: 1108 ATPPSPKGGLATPP 1121
Score = 48.9 bits (115), Expect = 8e-06
Identities = 53/181 (29%), Positives = 60/181 (33%), Gaps = 10/181 (5%)
Query: 46 SPLQTPTEDGSEEP----GSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSK 101
SP PT + P G T K PT A G T
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272
Query: 102 SKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK 161
S G G KGA + P P A PA TPP+PK P + PPK
Sbjct: 1273 SLKG-GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT-PPPK 1330
Query: 162 SGDRSGYSSPGSP-GTPGSRSRTPSLPTPPTREPKKVAVVRTPP-KSPSSAKSRLQTAPV 219
+P SP GTP + TPS PT K TPP +PS T P
Sbjct: 1331 GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG--PTPPAATPSHKGGPAMTPPS 1388
Query: 220 P 220
P
Sbjct: 1389 P 1389
Score = 48.1 bits (113), Expect = 1e-05
Identities = 57/230 (24%), Positives = 78/230 (33%), Gaps = 34/230 (14%)
Query: 44 KESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSK 103
K SP P + P K TPT A P+ G A S
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH-- 1378
Query: 104 DGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRI----PAKTPPAPKT-----PP 154
KG T + RG A P KG + + P K P P T P
Sbjct: 1379 ----------KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP 1428
Query: 155 SSGE--PPKSGDRSGYSSP------GSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKS 206
S G+ PP S +P G P TP S+ P+LP PK+ + S
Sbjct: 1429 SKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG-DPTLPAVTPPSPKEPPAPKQVATS 1487
Query: 207 PSSAKSRLQTAPVPMPDLKNV----KSKIGSTENLKHQPGGGKVQIINKK 252
S K+ AP+ P L V ++ +T + + P +++KK
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537
Score = 42.0 bits (97), Expect = 0.001
Identities = 63/238 (26%), Positives = 82/238 (34%), Gaps = 57/238 (23%)
Query: 26 QGGYTMHQDQEGDTDAGL----KESPLQTPTEDGSEEPGSETSDAKSTPTAEAE-EAGIG 80
+GG T +EG T K P TP S + G K PT+ A
Sbjct: 1357 KGGPTTPSSKEGPTPPAATPSHKGGPAMTPP---SPKRGPAIPSPKGDPTSPAVIPLSPK 1413
Query: 81 DTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANAT 140
P+ G T ++ T KKA A G A P KG
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS-----APKGGPATPSSKGDPT-- 1466
Query: 141 RIPAKTPPAPKTPPS------SGEPPKSGDRSGY-----------SSPGS-PGTPGSRSR 182
+PA TPP+PK PP+ S P K+ SSP P TP SR R
Sbjct: 1467 -LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR-R 1524
Query: 183 TPSLPT-------------------PPTR---EPKKVAVVRTPPKSPSSAKSRLQTAP 218
P PT PP PKK + TP ++P++ S+ ++P
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582
Score = 39.3 bits (90), Expect = 0.007
Identities = 33/123 (26%), Positives = 46/123 (37%), Gaps = 13/123 (10%)
Query: 111 KKAKGADGKTKIATPRGAAPPGQKGQANATRI---PAKTPPAPKTPPSSGEPPKSGDRSG 167
K+A + ++P P KG + + PA T P+PK P+ G
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627
Query: 168 YSSPGSPGTPGSRSRTPS----LPTPPTREPKKV------AVVRTPPKSPSSAKSRLQTA 217
++P GTP S TPS PT P K+ A P K +A + A
Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687
Query: 218 PVP 220
P P
Sbjct: 1688 PAP 1690
Score = 37.4 bits (85), Expect = 0.025
Identities = 60/226 (26%), Positives = 82/226 (36%), Gaps = 35/226 (15%)
Query: 39 TDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTA-EAEEAGIGDTP----SLEDEAAGHV 93
T KE+P S E G T K TPT+ + + D+P S+ + V
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV 1665
Query: 94 TQARMVSKSKDG-TGSDDKKAKGADGKTKIAT-PRGAAPPGQKGQA------------NA 139
QA +K G T + A T I T P P +K A N
Sbjct: 1666 PQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNG 1725
Query: 140 TRIPAKT-PPAPKTP--PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP-----PT 191
++ P T PAP P S + K D S +S G P S++ TP P
Sbjct: 1726 SKGPLSTVAPAPLLPVQKDSSKTAKGKDAS-HSPKGPLAPPESKASTPLTAAAFEKVLPK 1784
Query: 192 REPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENL 237
E V+ +PP S L AP P+P L + + S+ L
Sbjct: 1785 PESASVSAAPSPPVS-------LPLAPSPVPTLPPKQQFLPSSPGL 1823
Score = 37.0 bits (84), Expect = 0.033
Identities = 38/147 (25%), Positives = 55/147 (37%), Gaps = 28/147 (19%)
Query: 124 TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPP---------KSGDRSGYSSPGSP 174
TP PP + + AT P TP +P PSS + K G +S G P
Sbjct: 1615 TPPAVTPPSPE-KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLP 1673
Query: 175 GTPGSRS-----------RTPSLPTPPTREP--KKVAVVRTP----PKSPSSAKSRLQT- 216
G + TP + P + P KK + P P + + +K L T
Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTV 1733
Query: 217 APVPMPDLKNVKSKIGSTENLKHQPGG 243
AP P+ ++ SK ++ H P G
Sbjct: 1734 APAPLLPVQKDSSKTAKGKDASHSPKG 1760
Score = 36.6 bits (83), Expect = 0.043
Identities = 37/117 (31%), Positives = 48/117 (41%), Gaps = 20/117 (17%)
Query: 122 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGE---PPKSGDRSGYSSPGSPG-TP 177
I TP+ A P A+ PA TP K PS E PP S +P P TP
Sbjct: 1564 IPTPKEA--PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621
Query: 178 GSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 234
S + P+ P P +PP +PSS K T+P +V K+G+T
Sbjct: 1622 PSPEKGPATPAPK-------GTPTSPPVTPSSLKDS-PTSPA------SVTCKMGAT 1664
Score = 36.2 bits (82), Expect = 0.056
Identities = 50/189 (26%), Positives = 68/189 (35%), Gaps = 27/189 (14%)
Query: 48 LQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTG 107
+ PT G P ++ S A S P A G L A + + S SK G
Sbjct: 1696 ITAPTRKG---PQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS-SKTAKG 1751
Query: 108 SD---DKKAKGADGKTKIATPRGAAP-------PGQKGQANATRIPAKTPPAPKTPPSSG 157
D K A ++K +TP AA P + A P P AP P+
Sbjct: 1752 KDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL- 1810
Query: 158 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA 217
PPK P +PG +PS P P E + + ++ P P S Q+
Sbjct: 1811 -PPKQ--------QFLPSSPGLVLESPSKPLAPADEDELLPLI---PPEPISGGVPFQSV 1858
Query: 218 PVPMPDLKN 226
V MP K+
Sbjct: 1859 LVNMPTPKS 1867
Score = 30.4 bits (67), Expect = 3.1
Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 135 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 194
G+A T +PA P+ + P S S ++ G PG P+LP P + P
Sbjct: 3 GEATET-VPATEQELPQPQAETAVLPMSSALSVTAALGQPG--------PTLPPPCSPAP 53
Query: 195 KKVAVVRTPPKSPSSAKSRLQTAPVPMP 222
++ + SP + S + + P+ +P
Sbjct: 54 QQCPLSAANQASPFPSPSTIASTPLEVP 81
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 50.4 bits (119), Expect = 3e-06
Identities = 45/171 (26%), Positives = 62/171 (36%), Gaps = 17/171 (9%)
Query: 45 ESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKD 104
E P Q+ + S G+ S A + G G P +D + V A + S+
Sbjct: 541 EPPPQSSRAESSSGGGTVPSSAGILE--QGPSPGDGSPPKPKDPVSAAVP-APGRNNSQI 597
Query: 105 GTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGD 164
+G + +A + + P AA P A + PA PP P PP
Sbjct: 598 ASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPP--------- 648
Query: 165 RSGYSSPGSPGTPGSRSRTPSL-PTPPTREPKKVAVVRTPPKSPSSAKSRL 214
PG + G+ PSL P PPTR P P SA S+L
Sbjct: 649 ----GHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQL 695
Score = 36.2 bits (82), Expect = 0.056
Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 8/112 (7%)
Query: 125 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 184
P A P + G + P +TP P TPP + P S + G+P T ++
Sbjct: 736 PNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNP-SLPAPQTLAGGNPET--AQPHAG 792
Query: 185 SLPTP-PTREPKKVAVVRTPPKSP----SSAKSRLQTAPVPMPDLKNVKSKI 231
+LP P P +P+ V PP+ P + S TAP + + S++
Sbjct: 793 TLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRV 844
Score = 33.5 bits (75), Expect = 0.36
Identities = 42/186 (22%), Positives = 64/186 (34%), Gaps = 21/186 (11%)
Query: 39 TDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARM 98
+ AG+ E Q P+ P + + + P + I + AAG +
Sbjct: 560 SSAGILE---QGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAG--SHQLS 614
Query: 99 VSKSKDGTGSDDKKAKGADGKTKIATPR-GAAPPGQKG---QANATRIPAKTPPAPKTPP 154
+ + + G + A K A P+ G PPG G + ++ P P P T
Sbjct: 615 MGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRS 674
Query: 155 SSGEPPKSGDRSGYSSPGSPGTPG--SRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKS 212
S +G PG P P S R S P + P PP+ P+ A
Sbjct: 675 PSPPTQHTG-----QPPGQPSAPSQLSAPRRYSSSLSPIQAPN-----HPPPQPPTQATP 724
Query: 213 RLQTAP 218
+ T P
Sbjct: 725 LMHTKP 730
Score = 33.1 bits (74), Expect = 0.47
Identities = 23/86 (26%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 143 PAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP--KKVAVV 200
P PP TP +P G + + P G P PTPP+ P K+ +
Sbjct: 714 PPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSL 773
Query: 201 RTPPK----SPSSAKSRLQTAPVPMP 222
P +P +A+ T P P P
Sbjct: 774 PAPQTLAGGNPETAQPHAGTLPRPRP 799
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 50.4 bits (119), Expect = 3e-06
Identities = 43/175 (24%), Positives = 64/175 (36%), Gaps = 20/175 (11%)
Query: 47 PLQTPTEDGSEEPGSETSDA---KSTPTAEAEEAGI---GDTPSLEDEAAGHVTQARMVS 100
PL TP+ + S G+++ + P + A G ++P + A +
Sbjct: 456 PLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESPPKPKDPVSAAVPAPGRN 515
Query: 101 KSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPP 160
S+ +G + +A + + P AA P A + PA PP P PP
Sbjct: 516 NSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPP----- 570
Query: 161 KSGDRSGYSSPGSPGTPGSRSRTPSL-PTPPTREPKKVAVVRTPPKSPSSAKSRL 214
PG + G+ PSL P PPTR P P SA S+L
Sbjct: 571 --------GHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQL 617
Score = 36.2 bits (82), Expect = 0.056
Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 8/112 (7%)
Query: 125 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 184
P A P + G + P +TP P TPP + P S + G+P T ++
Sbjct: 658 PNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNP-SLPAPQTLAGGNPET--AQPHAG 714
Query: 185 SLPTP-PTREPKKVAVVRTPPKSP----SSAKSRLQTAPVPMPDLKNVKSKI 231
+LP P P +P+ V PP+ P + S TAP + + S++
Sbjct: 715 TLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRV 766
Score = 33.1 bits (74), Expect = 0.47
Identities = 23/86 (26%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 143 PAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP--KKVAVV 200
P PP TP +P G + + P G P PTPP+ P K+ +
Sbjct: 636 PPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSL 695
Query: 201 RTPPK----SPSSAKSRLQTAPVPMP 222
P +P +A+ T P P P
Sbjct: 696 PAPQTLAGGNPETAQPHAGTLPRPRP 721
Score = 32.0 bits (71), Expect = 1.1
Identities = 44/203 (21%), Positives = 67/203 (33%), Gaps = 27/203 (13%)
Query: 29 YTMHQDQEGDTDAGLKESPLQTPTEDGS-------EEPGSETSDAKSTPTAEAEEAGIGD 81
++ H + D+ ++ P +G +P S A P + G
Sbjct: 464 HSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESPPKPKDPVSAAVPAPGRNNSQIASGQ 523
Query: 82 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPR-GAAPPGQKG---QA 137
+ +AA Q M + + G + A K A P+ G PPG G +
Sbjct: 524 N---QPQAAAGSHQLSM-GQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSS 579
Query: 138 NATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPG--SRSRTPSLPTPPTREPK 195
++ P P P T S +G PG P P S R S P + P
Sbjct: 580 GTSQHPPSLSPKPPTRSPSPPTQHTG-----QPPGQPSAPSQLSAPRRYSSSLSPIQAPN 634
Query: 196 KVAVVRTPPKSPSSAKSRLQTAP 218
PP+ P+ A + T P
Sbjct: 635 -----HPPPQPPTQATPLMHTKP 652
>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
Length = 1006
Score = 50.1 bits (118), Expect = 4e-06
Identities = 44/167 (26%), Positives = 69/167 (41%), Gaps = 21/167 (12%)
Query: 46 SPLQTPTEDGSEEPGSETSDAKSTP---TAEAEEAGIGDTPSLEDEAAGHVTQARMVSKS 102
+PL P ++ PG + + P + EA + G+ P EAAG ++ +
Sbjct: 343 APLPRPAPLPAKRPGDSPASKRPRPGGVSPEARDPPKGENPLCSSEAAGETGPTQV--RG 400
Query: 103 KDGTGSDDKKAKGADGKT--KIATPRGAAPPGQKGQANATRIPAKTPPAPKT-------- 152
D G + KG +GK + +PR A P + G+ +R P P+T
Sbjct: 401 PDALGGGRLQGKGREGKAPGEGVSPRPAPP--RLGKPPRSRPPQGLAQPPETFFFERSRL 458
Query: 153 PPSSGEPPKSGDRSGYSSPGSPGT----PGSRSRTPSLPTPPTREPK 195
P S E ++G + G P SRS PS P PP ++P+
Sbjct: 459 VPVSAELERAGHGFSGDAEARSGDLGARPASRSSLPSAPAPPAQQPQ 505
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 50.1 bits (118), Expect = 4e-06
Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 14/157 (8%)
Query: 77 AGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATP-RGAAPPGQKG 135
AG G P+L H + +++ G+ +D A A + P GAA P G
Sbjct: 719 AGWGGHPAL---GCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPG 775
Query: 136 QANATRIPAKTPP--APKTPPSSGEPPK--SGDRSGYSSPG-SPGTPGSRSRTP-----S 185
+ P PP AP P +S +PP + SG SSPG PG G + TP +
Sbjct: 776 RGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGA 835
Query: 186 LPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 222
P E + V R PP+ P R P P+P
Sbjct: 836 FPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLP 872
Score = 37.4 bits (85), Expect = 0.025
Identities = 47/198 (23%), Positives = 65/198 (32%), Gaps = 37/198 (18%)
Query: 37 GDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQA 96
G+T G PL ++G+ EPG+E ++ A AG D S G
Sbjct: 1097 GETAPG----PLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVG----- 1147
Query: 97 RMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS 156
GT G D K PP P PP P+ P
Sbjct: 1148 -------TGTAPGGGPGSGVDAKAGWVDNTRPQPP-----------PPPLPPPPEAQPRR 1189
Query: 157 GEPPKSGDRSGYSSPGSPGTPGSRSRTPSL------PTPPTRE----PKKVAVVRTPPKS 206
EP R + G PG P SR+ + P P R+ P+ + P +
Sbjct: 1190 LEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGN 1249
Query: 207 PSSAKSRLQTAPVPMPDL 224
K+RL + +P L
Sbjct: 1250 SEQIKARLSRLSLALPPL 1267
Score = 30.4 bits (67), Expect = 3.1
Identities = 45/176 (25%), Positives = 62/176 (35%), Gaps = 35/176 (19%)
Query: 53 EDGSEEPGSETSDAKST-PTAEAEEAGIG-----DTPSLEDEAAGHVTQARMVSKSKDGT 106
EDG +E E D ++ P A A G G P + A + + K
Sbjct: 1305 EDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARP-LRGLLKSPR 1363
Query: 107 GSDDKKAKGADGKTKIATPRGAAPP---GQKGQANATRIPA--------KTPPAPKTPPS 155
G+D+ + + K K+ + G Q+ N + A TPPAP TPP
Sbjct: 1364 GADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPPH 1423
Query: 156 SGEP----PKSGDRSGYS-----------SPGSPGTPGSRSRTPSL--PTPPTREP 194
P P + G S PG P S +P+L P PP R P
Sbjct: 1424 PATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVSPALETPGPPARAP 1479
Score = 30.0 bits (66), Expect = 4.0
Identities = 33/114 (28%), Positives = 41/114 (35%), Gaps = 24/114 (21%)
Query: 70 PTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIA-TPRGA 128
P A A+ A D PS V+ G S K + +T+ +P GA
Sbjct: 789 PRAPADPAASPDPPSA-------------VASPGSGLSSPGPKPGDSGYETETPFSPEGA 835
Query: 129 APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSR 182
P G G A +P P AP PP G P D PG PG R +
Sbjct: 836 FPGG--GAAEEEGVPR--PRAPPEPPDPGAPRPPPD------PGPLPLPGPREK 879
>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
Length = 2603
Score = 49.3 bits (116), Expect = 6e-06
Identities = 53/198 (26%), Positives = 78/198 (39%), Gaps = 20/198 (10%)
Query: 43 LKESPLQTPTEDGSEEPGSETSDAKSTP------------TAEAEEAGIGDTPSLEDEAA 90
L SP T + S PG+ T+ + S+P T+ A + T S + A
Sbjct: 1965 LTSSPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAP 2024
Query: 91 GHVTQARMVSKSKDGTGSDDKKAKGAD-GKTKIATPRGAAPPGQKGQANATRIPAKTPPA 149
+ T +K S + A G +P A+++ A +PP
Sbjct: 2025 TNATYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPV 2084
Query: 150 PKTPPSSGEPPKSGDRSGYSSPGS--PGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSP 207
+T ++ PP S SG SS S PGS S+ P P ++ P + PP +
Sbjct: 2085 VET--TNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLAT 2142
Query: 208 SSAKSRL-QTAPV--PMP 222
SSA + TAPV PMP
Sbjct: 2143 SSAPVAVPSTAPVTYPMP 2160
>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
Length = 2352
Score = 49.3 bits (116), Expect = 6e-06
Identities = 53/198 (26%), Positives = 78/198 (39%), Gaps = 20/198 (10%)
Query: 43 LKESPLQTPTEDGSEEPGSETSDAKSTP------------TAEAEEAGIGDTPSLEDEAA 90
L SP T + S PG+ T+ + S+P T+ A + T S + A
Sbjct: 1714 LTSSPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAP 1773
Query: 91 GHVTQARMVSKSKDGTGSDDKKAKGAD-GKTKIATPRGAAPPGQKGQANATRIPAKTPPA 149
+ T +K S + A G +P A+++ A +PP
Sbjct: 1774 TNATYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAGSPPV 1833
Query: 150 PKTPPSSGEPPKSGDRSGYSSPGS--PGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSP 207
+T ++ PP S SG SS S PGS S+ P P ++ P + PP +
Sbjct: 1834 VET--TNTRPPNSSSSSGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLAT 1891
Query: 208 SSAKSRL-QTAPV--PMP 222
SSA + TAPV PMP
Sbjct: 1892 SSAPVAVPSTAPVTYPMP 1909
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/218 (26%), Positives = 84/218 (38%), Gaps = 31/218 (14%)
Query: 21 GDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIG 80
G RK + H E A + S G + P S + + +TP + +G
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPS-----AGGGLQRPASRSLSSSATPLSSPARSG-- 256
Query: 81 DTPSLED--EAAGHVTQAR------MVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG 132
PS A H +Q + + D A G + +ATP +P G
Sbjct: 257 --PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP---SPSG 311
Query: 133 QKGQA------NATRIPAKTPPAPK--TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 184
K + AT +PA PP+P TP P S S + P P TP S++ P
Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA-PP 370
Query: 185 SLPTPPTREPKKVAVVRTPPKSPSSAKS-RLQTAPVPM 221
S+ TPP + P + + P + P S S LQ P P+
Sbjct: 371 SMTTPPMQAPPSLQTI-PPIQVPHSLTSPSLQAPPSPL 407
Score = 42.0 bits (97), Expect = 0.001
Identities = 59/231 (25%), Positives = 75/231 (32%), Gaps = 38/231 (16%)
Query: 21 GDRKDQGGYT--------MHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTA 72
G R+D G T + + T+ GL +E P S A T
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 73 EAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG 132
E A A G + + S S T G + TPR A P
Sbjct: 219 EPSPAA-----RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR---GTPRAPAHPS 270
Query: 133 Q---KGQANATRIPAKTPP----APKTPPSSGEPPKSGDRSGYSS-----PGSPGTPGSR 180
Q KG A R P TPP AP P S P + SG + P + TP
Sbjct: 271 QPKPKG-LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA 329
Query: 181 SRTPSLP--TP-------PTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 222
+ PS P TP P+ P + P PS A + T P+ P
Sbjct: 330 TLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380
Score = 40.0 bits (92), Expect = 0.004
Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 5/97 (5%)
Query: 129 APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGT--PGSRSRTPSL 186
+PP + + P + PPA TPP P G +P SP P S TP
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG-QAPFSPSASLPMSPLATPPP 829
Query: 187 PTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPD 223
PP + V +PP SP+ R P P PD
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPR--RPPTPGPD 864
Score = 39.7 bits (91), Expect = 0.005
Identities = 36/103 (34%), Positives = 44/103 (42%), Gaps = 16/103 (15%)
Query: 123 ATPRGAAPPGQ---KGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGS 179
A P AAPP Q A+ P+ TPP P+ PP PP P SP P S
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPP-PQAPPPLAAPP-------LQVPPSP--PAS 744
Query: 180 RSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVP 220
+PS TPP R P +A ++ PP P+S P P
Sbjct: 745 PPMSPS-ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Score = 38.9 bits (89), Expect = 0.009
Identities = 31/108 (28%), Positives = 42/108 (38%), Gaps = 10/108 (9%)
Query: 122 IATPRGAAPPGQKGQANATRIPAKTPPAPKT-------PPSSGEPPKSGDRSGYSSPGSP 174
+A P APP + + +P AP P S PP ++ +S P SP
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASP 683
Query: 175 GTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 222
P S S TP PP+ + V +PP SP + S P P
Sbjct: 684 --PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729
Score = 37.7 bits (86), Expect = 0.019
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 6/78 (7%)
Query: 143 PAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRT 202
P+ TPP+ + PPS PP S +SP P S S TP PP + V +
Sbjct: 687 PSATPPS-QAPPSLAAPPLQVPPSPPASP-----PMSPSATPPPQAPPPLAAPPLQVPPS 740
Query: 203 PPKSPSSAKSRLQTAPVP 220
PP SP + S VP
Sbjct: 741 PPASPPMSPSATPPPRVP 758
Score = 37.4 bits (85), Expect = 0.025
Identities = 34/113 (30%), Positives = 46/113 (40%), Gaps = 24/113 (21%)
Query: 122 IATPRGAAP-PGQKGQANATRIPAKTP-----PAPKTPPSSGEPPKSGDRSGYSSPGSPG 175
+ TP AP P Q + T P +TP P P+ PP+ PP G P P
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG------LPSPPL 611
Query: 176 TPGSRSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPMPDLKN 226
+P L TPP + P +A+ ++ PP P+S L P P N
Sbjct: 612 SP--------LATPPPQAPPXLALPPLQAPPSPPASPP--LSPLATPSPQAPN 654
Score = 36.6 bits (83), Expect = 0.043
Identities = 35/105 (33%), Positives = 46/105 (43%), Gaps = 8/105 (7%)
Query: 123 ATPRGAAPPGQ---KGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS-PGSPGTPG 178
A P AAPP Q A+ P+ TPP P+ PP PP S +S P SP
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPP-PRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784
Query: 179 SRSRTPSLPTPPTRE-PKKVAVVRTPPKSPSSAKSRLQTAPVPMP 222
P+L TPP + P A P ++P S + L +P+ P
Sbjct: 785 PPQAPPALATPPLQALPSPPA--SFPGQAPFSPSASLPMSPLATP 827
Score = 35.0 bits (79), Expect = 0.12
Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 14/102 (13%)
Query: 123 ATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSR 182
ATP APP A ++P P +P PS+ PP++ P +
Sbjct: 689 ATPPSQAPPSLA--APPLQVPPSPPASPPMSPSATPPPQA----------PPPLAAPPLQ 736
Query: 183 TPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL 224
P P+PP P + P P A LQ P P L
Sbjct: 737 VP--PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Score = 32.0 bits (71), Expect = 1.1
Identities = 26/105 (24%), Positives = 41/105 (39%), Gaps = 8/105 (7%)
Query: 120 TKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGS 179
+ IATP APP P + P+P P + PP++ +P +P +
Sbjct: 585 SSIATPPPQAPPALASP------PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638
Query: 180 RSRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPMP 222
L TP + P +AV ++ P P S + +P P
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683
Score = 29.6 bits (65), Expect = 5.2
Identities = 45/182 (24%), Positives = 62/182 (34%), Gaps = 18/182 (9%)
Query: 43 LKESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKS 102
L SPL TP+ G++ D +TP A + +P L T + S
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLP----ATLPPSPPL-------ATPLPLAPPS 347
Query: 103 KDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKS 162
S A P PP Q + T IP P T PS PP
Sbjct: 348 PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT-IPPIQVPHSLTSPSLQAPPSP 406
Query: 163 GDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA--KSRLQTAPVP 220
S + S G+P ++ L T P++ T P P+S S AP+
Sbjct: 407 LALSSLQATTSLGSPTLQATHSFL----TMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462
Query: 221 MP 222
+P
Sbjct: 463 LP 464
Score = 29.3 bits (64), Expect = 6.8
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 17/123 (13%)
Query: 113 AKGADGKTKIATPRG----AAPPGQKGQANATRIPAKTPPAPKT-PPSSGEPPKSGDRSG 167
A GA G+ +A G A P +A TR + P + PP+SG ++
Sbjct: 49 AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN 108
Query: 168 YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRT---------PPKSPSSAKSRLQTA- 217
+SPG +PG S T + P P ++ +++ T P +S SA +R T+
Sbjct: 109 -TSPGPVSSPGRASGT-TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166
Query: 218 PVP 220
P P
Sbjct: 167 PTP 169
Score = 28.9 bits (63), Expect = 8.9
Identities = 26/103 (25%), Positives = 34/103 (33%), Gaps = 6/103 (5%)
Query: 122 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 181
+ PR PG + R+ P P PP PP S S P G S +
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGP--PP----PPSRSPSSTLSGPDLAGHSSSAT 905
Query: 182 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL 224
TP P+ A PP + +A + P P L
Sbjct: 906 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 948
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 48.1 bits (113), Expect = 1e-05
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 18/152 (11%)
Query: 55 GSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAK 114
G+ EPG + + P E EAGI P + E + + G + +
Sbjct: 430 GAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGE----R 485
Query: 115 GADGKTKIATPRGAAPPGQKGQANATRIPAKTPP--APKTPPSSGEPPKSGDRS------ 166
GA G A P G PG+KG A P P A P G P G R
Sbjct: 486 GAPGFRGPAGPNGI--PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPG 543
Query: 167 GYSSPGSPGTPGSRSRT----PSLPTPPTREP 194
G S G PG PGS+ + P P+ P +P
Sbjct: 544 GPGSDGKPGPPGSQGESGRPGPPGPSGPRGQP 575
Score = 43.1 bits (100), Expect = 5e-04
Identities = 49/170 (28%), Positives = 63/170 (37%), Gaps = 37/170 (21%)
Query: 15 AGTYGLGDRKDQGGYTMHQDQEGDTDA-GLKESPLQTPTEDGSEEPGSETSDAKSTPTAE 73
AG G K G+ ++G+T A GLK E+G PG + P
Sbjct: 254 AGIPGFPGMKGHRGFDGRNGEKGETGAPGLKG-------ENGL--PGENGAPGPMGPRGA 304
Query: 74 AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAA---- 129
E G P AAG ++ DG A+G+DG+ P G A
Sbjct: 305 PGERGRPGLPG----AAG--------ARGNDG-------ARGSDGQPGPPGPPGTAGFPG 345
Query: 130 PPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGS 179
PG KG+ PA +P + P GEP G PG PG GS
Sbjct: 346 SPGAKGEVG----PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGS 391
Score = 43.1 bits (100), Expect = 5e-04
Identities = 33/92 (35%), Positives = 40/92 (43%), Gaps = 11/92 (11%)
Query: 102 SKDGTGSDDKKAK-GADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPP 160
S G GSD K G+ G++ P G P G +GQ P PK + G P
Sbjct: 541 SPGGPGSDGKPGPPGSQGESGRPGPPG--PSGPRGQPGVMGFPG-----PKG--NDGAPG 591
Query: 161 KSGDRSGYSSPGSPGTPGSRSRT-PSLPTPPT 191
K+G+R G PG G PG T P P PT
Sbjct: 592 KNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623
Score = 42.4 bits (98), Expect = 8e-04
Identities = 46/185 (24%), Positives = 61/185 (32%), Gaps = 9/185 (4%)
Query: 40 DAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMV 99
+ G SP + + + +PG + S P GI A
Sbjct: 910 NTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRG 969
Query: 100 SKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAK--TPPAPKTPPSSG 157
S G + K GA+G + P G P G G A P + P + P G
Sbjct: 970 SPGPQGVKGESGKP-GANGLSGERGPPG--PQGLPGLAGTAGEPGRDGNPGSDGLPGRDG 1026
Query: 158 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA 217
P GDR SPG+PG PG P P P K + P P+ A +
Sbjct: 1027 SPGGKGDRGENGSPGAPGAPGH----PGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSR 1082
Query: 218 PVPMP 222
P P
Sbjct: 1083 GAPGP 1087
Score = 38.5 bits (88), Expect = 0.011
Identities = 35/127 (27%), Positives = 45/127 (35%), Gaps = 10/127 (7%)
Query: 55 GSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDG-TGSDDKKA 113
G+ PG E + P AG + E G + K + G G+D
Sbjct: 697 GAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPG 756
Query: 114 K-GADGKT-KIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP 171
K G G T I P A PG KG+ A +P P G P + G+
Sbjct: 757 KDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPR-------GSPGERGETGPPGPA 809
Query: 172 GSPGTPG 178
G PG PG
Sbjct: 810 GFPGAPG 816
Score = 37.0 bits (84), Expect = 0.033
Identities = 36/154 (23%), Positives = 47/154 (30%), Gaps = 20/154 (12%)
Query: 59 PGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADG 118
PG SD K P E+G P K DG + + G G
Sbjct: 542 PGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGG 601
Query: 119 KTKIATPRGAAPPGQKGQANATRIPAKT----------PPAPK----TPPSSGEPPKSGD 164
P PPG+ G+ P T PP P+ P + G P ++G
Sbjct: 602 ------PGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGK 655
Query: 165 RSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVA 198
G G PG+ P R P +A
Sbjct: 656 PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLA 689
Score = 36.6 bits (83), Expect = 0.043
Identities = 35/102 (34%), Positives = 39/102 (38%), Gaps = 18/102 (17%)
Query: 107 GSDDKKAKGADGKTKIATPRG----AAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKS 162
G D A G G +A G A PPG +G A P P A TP G P
Sbjct: 673 GKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP-PGAAGTPGLQGMP--- 728
Query: 163 GDRSGYSSP------GSPGTPGS----RSRTPSLPTPPTREP 194
G+R G SP G PG PG+ P PT P P
Sbjct: 729 GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770
Score = 35.4 bits (80), Expect = 0.095
Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Query: 140 TRIP-AKTPPAPKTPPSS-GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 190
TR P + P PK P G P ++GD PGSPG+PG S PT P
Sbjct: 96 TRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148
Score = 35.0 bits (79), Expect = 0.12
Identities = 48/226 (21%), Positives = 78/226 (34%), Gaps = 31/226 (13%)
Query: 42 GLKESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSK 101
G + SP + S +PG+ + P G+ T E G+ + +
Sbjct: 966 GPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAG-EPGRDGNPGSDGLPGR 1024
Query: 102 SKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA-----PKTPPSS 156
G D+ G+ G P PPG G A + ++ PA P S
Sbjct: 1025 DGSPGGKGDRGENGSPGAP--GAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSR 1082
Query: 157 GEPPKSGDRS-----------------GY-SSPGSPGTPGSRSRTPSLPTPPTREPKKVA 198
G P G R G+ +PG+PG+PG + ++ +P P+
Sbjct: 1083 GAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPV 1142
Query: 199 VVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKH--QPG 242
PP ++ P+ P + + + GS + H QPG
Sbjct: 1143 GPSGPPGKDGTSG---HPGPIGPPGPRGNRGERGSEGSPGHPGQPG 1185
Score = 34.7 bits (78), Expect = 0.16
Identities = 29/94 (30%), Positives = 34/94 (36%), Gaps = 15/94 (15%)
Query: 114 KGADGKTKIATPRG----AAPPGQKGQANATRIPAKTPPA--------PKTPPSSGEPPK 161
KG G +A P G A PPG +G P A P P S+G P
Sbjct: 833 KGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGP 892
Query: 162 SGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK 195
G SPG G PG T + +P PK
Sbjct: 893 PGPSG---SPGKDGPPGPAGNTGAPGSPGVSGPK 923
Score = 33.9 bits (76), Expect = 0.28
Identities = 36/132 (27%), Positives = 45/132 (34%), Gaps = 18/132 (13%)
Query: 60 GSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGT--------GSDDK 111
G S + T AG P E G + K + G GS
Sbjct: 792 GPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPA 851
Query: 112 KAKGADG-KTKIATPRGAAPPGQKGQANATRIPAKTPPA----PKTPPSSGEPPKSGDRS 166
G G K + +P G PG G A +P PP P P SG P K G
Sbjct: 852 GPPGPQGVKGERGSPGG---PGAAGFPGARGLPG--PPGSNGNPGPPGPSGSPGKDGPPG 906
Query: 167 GYSSPGSPGTPG 178
+ G+PG+PG
Sbjct: 907 PAGNTGAPGSPG 918
Score = 33.5 bits (75), Expect = 0.36
Identities = 45/190 (23%), Positives = 62/190 (32%), Gaps = 29/190 (15%)
Query: 16 GTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEAE 75
G G G +Q G+ P P G P + D +S
Sbjct: 183 GPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGK--DGESGRPGRPG 240
Query: 76 EAGIGDTPSLEDEAAGHVTQARMVSKSKDG-------TGSDDKKAK----GADGKTKIAT 124
E G+ P ++ A + DG TG+ K + G +G
Sbjct: 241 ERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMG 300
Query: 125 PRGAAPPGQKGQ----------ANATRIPAKTPPAPKTPPSS----GEPPKSGDRSGYSS 170
PRGA PG++G+ N + P P PP + G P G+ S
Sbjct: 301 PRGA--PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGS 358
Query: 171 PGSPGTPGSR 180
PGS G PG R
Sbjct: 359 PGSNGAPGQR 368
Score = 32.3 bits (72), Expect = 0.80
Identities = 39/145 (26%), Positives = 51/145 (35%), Gaps = 16/145 (11%)
Query: 41 AGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVS 100
AG +P Q G E G+ + P A G G P+ G +
Sbjct: 809 AGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPG-GSGPAGPPGPQG----VKGER 863
Query: 101 KSKDGTGSDDKKAKGADGKTKIATPRGA----APPGQKGQA--NATRIPAKTPPAPKTPP 154
S G G A G G + P G+ PPG G + PA AP +P
Sbjct: 864 GSPGGPG-----AAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPG 918
Query: 155 SSGEPPKSGDRSGYSSPGSPGTPGS 179
SG +G SPG+ G PG+
Sbjct: 919 VSGPKGDAGQPGEKGSPGAQGPPGA 943
Score = 32.3 bits (72), Expect = 0.80
Identities = 23/68 (33%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 114 KGADGKTKIATPRG-AAPPGQKGQANATRIPAKT-PPAPKTPPSSGEPPKSGDRSGYSSP 171
+GA G A PRG P G G+ + P PP P+ + GE G P
Sbjct: 1127 QGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRG--NRGERGSEGSPGHPGQP 1184
Query: 172 GSPGTPGS 179
G PG PG+
Sbjct: 1185 GPPGPPGA 1192
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 15/74 (20%)
Query: 117 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGT 176
D K+ +A A PG G PP P PP + P S GY P PG
Sbjct: 159 DVKSGVAVGGLAGYPGPAG-----------PPGPPGPPGTSGHPGSPGSPGYQGP--PGE 205
Query: 177 PGSRSRTPSLPTPP 190
PG PS P P
Sbjct: 206 PGQAG--PSGPPGP 217
Score = 31.6 bits (70), Expect = 1.4
Identities = 43/178 (24%), Positives = 56/178 (31%), Gaps = 17/178 (9%)
Query: 16 GTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSE----EPGSETSDAKSTPT 71
G G G K G Q +G G P E G + PG+ +
Sbjct: 621 GPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAP 680
Query: 72 AEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGA--- 128
E G+ P L A + + G A G G + RG
Sbjct: 681 GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPG----AAGTPGLQGMPGERGGLGS 736
Query: 129 -APPGQKGQAN---ATRIPAKTPPAPKTPPSSGEPP--KSGDRSGYSSPGSPGTPGSR 180
P G KG+ A +P K P T P P + GD+ +PG PG G R
Sbjct: 737 PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPR 794
Score = 31.2 bits (69), Expect = 1.8
Identities = 19/51 (37%), Positives = 21/51 (41%), Gaps = 11/51 (21%)
Query: 147 PPAPKTPPSS-------GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 190
P AP PP+ G+P G PG PG PGS P P PP
Sbjct: 92 PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGS----PGSPGPP 138
Score = 31.2 bits (69), Expect = 1.8
Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 11/102 (10%)
Query: 110 DKKAKGADGKTKI-ATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGY 168
DK G G + P PPG+ G+ P AP P G+ G+R
Sbjct: 628 DKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPG-PKGDAGAPGAPGGKGDAGAPGER--- 683
Query: 169 SSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 210
PG G PG R PP E K A PP P +A
Sbjct: 684 GPPGLAGAPGLRGGA----GPPGPEGGKGAA--GPPGPPGAA 719
Score = 30.4 bits (67), Expect = 3.1
Identities = 22/87 (25%), Positives = 31/87 (35%), Gaps = 10/87 (11%)
Query: 110 DKKAKGADGKTKIATPRGA-APPGQKGQANATRIPAKTPPAPK-TPPSSGEPPKSGDRSG 167
++ + G G RG PPG G PP P +P G P +G+
Sbjct: 862 ERGSPGGPGAAGFPGARGLPGPPGSNGNPG--------PPGPSGSPGKDGPPGPAGNTGA 913
Query: 168 YSSPGSPGTPGSRSRTPSLPTPPTREP 194
SPG G G + +P + P
Sbjct: 914 PGSPGVSGPKGDAGQPGEKGSPGAQGP 940
Score = 29.6 bits (65), Expect = 5.2
Identities = 17/51 (33%), Positives = 19/51 (37%), Gaps = 10/51 (19%)
Query: 125 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPG 175
P G P G KG P P P +G+P G SPG PG
Sbjct: 99 PNGQGPQGPKGD----------PGPPGIPGRNGDPGIPGQPGSPGSPGPPG 139
Score = 29.6 bits (65), Expect = 5.2
Identities = 41/169 (24%), Positives = 47/169 (27%), Gaps = 31/169 (18%)
Query: 37 GDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQA 96
G D G SP PG KS E+ AG P Q
Sbjct: 1030 GKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQG 1089
Query: 97 RMVSKSKDGTGSDDKKAKGADGKTKI-ATPRGAAPPGQKGQANATRIPA----KTPPAPK 151
K + G ++ A G G P PG GQ A P + P P
Sbjct: 1090 PRGDKGETG----ERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPS 1145
Query: 152 TPPSS----------GEPPKSGDRSGYSS------------PGSPGTPG 178
PP G P G+R S PG PG PG
Sbjct: 1146 GPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/201 (20%), Positives = 72/201 (35%), Gaps = 12/201 (5%)
Query: 34 DQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHV 93
D+E + D +E+ T E + E SD+ S + A+ G D+ S + ++
Sbjct: 981 DEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSS 1040
Query: 94 TQARMVSKSKDGTGSDDKKAKGADGKTK---IATPRGAAPPGQKGQANATRIPAKTP--- 147
+ + S S + S ++ D + + A P + PP + + P
Sbjct: 1041 SSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERV 1100
Query: 148 ---PAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP-PTREPKKVAVVRTP 203
P P P + + S P +P P P P P P P + P
Sbjct: 1101 AGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPP 1160
Query: 204 PKS--PSSAKSRLQTAPVPMP 222
PK + + S ++ P P P
Sbjct: 1161 PKKRRKTVSFSAIEVVPAPEP 1181
Score = 32.3 bits (72), Expect = 0.80
Identities = 40/159 (25%), Positives = 54/159 (33%), Gaps = 15/159 (9%)
Query: 98 MVSKSKDGTGSDDKKAKGADGKTKIATPRG---AAPPGQKGQANATR-IPAKTPPAPKTP 153
MV ++D TGS+ G T P AP G G+ ATR P +P
Sbjct: 519 MVLGARD-TGSEVPSGSGHGPCTPPPAPANFEDVAPTGS-GEPGATRESPKANGQNQASP 576
Query: 154 PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTRE---------PKKVAVVRTPP 204
SSG+ + D SP TP + P P PP P PP
Sbjct: 577 CSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPP 636
Query: 205 KSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGG 243
+ P P P + + + + + L Q GG
Sbjct: 637 RPDGPPPPEYPPPPPPPPHIYDFVNSLELMDRLGAQWGG 675
Score = 28.9 bits (63), Expect = 8.9
Identities = 34/153 (22%), Positives = 48/153 (31%), Gaps = 16/153 (10%)
Query: 56 SEEPGSETSDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKG 115
S S T+ T A + + SL ++ + + +S D ++
Sbjct: 315 SASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYYESWN 374
Query: 116 ADGKTKIATPRGAA---PPGQKGQAN-ATRIPAK----TPPAP--------KTPPSSGEP 159
+ PR A PPG N A R P PP P + P S P
Sbjct: 375 RYQRHTSYPPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPP 434
Query: 160 PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTR 192
P+ + G G P RT P P R
Sbjct: 435 PEPPEPGGGGGGGGPSPEREEVRTSPRPASPAR 467
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/220 (25%), Positives = 71/220 (32%), Gaps = 29/220 (13%)
Query: 21 GDRKDQGGYT--------MHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTA 72
G R+D G T + + T+ GL +E P S A T
Sbjct: 150 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 209
Query: 73 EAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG 132
E A A G + + S S T G + TPR A P
Sbjct: 210 EPSPAA-----RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR---GTPRAPAHPS 261
Query: 133 Q---KGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTP 189
Q KG A R P TPP P+ G P S SP +P +P + +LP+P
Sbjct: 262 QPKPKG-LQALRPPQVTPPRKDAAPALG--PLSSSPLATPSPSAPPSPSAPPSLQTLPSP 318
Query: 190 PTREPKKVAVVRTPPK-------SPSSAKSRLQTAPVPMP 222
P P + P PS S L T P P
Sbjct: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358
Score = 42.0 bits (97), Expect = 0.001
Identities = 49/192 (25%), Positives = 74/192 (38%), Gaps = 28/192 (14%)
Query: 43 LKESPLQTPTEDGSEEPGSETS-----DAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQAR 97
L SPL TP+ P + S +TP ++A + +G +P+L+ T +
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS-LG-SPTLQ------ATHSF 341
Query: 98 MVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKT----- 152
+ S + +A A +A P APP + + +P AP
Sbjct: 342 LPSPPLSPLATPPPQAPPA-----LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 396
Query: 153 --PPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 210
P S PP ++ +S P SP P S S TP PP+ + V +PP SP +
Sbjct: 397 LQAPFS-PPPSPPVQAPFSPPASP--PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453
Query: 211 KSRLQTAPVPMP 222
S P P
Sbjct: 454 PSATPPPQAPPP 465
Score = 40.4 bits (93), Expect = 0.003
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 14/105 (13%)
Query: 123 ATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPG-SPGTPGSRS 181
A P AAPP Q + P + PPA TPP P S PG +P +P +
Sbjct: 462 APPPLAAPPLQLAKP-----PPQAPPALATPPLQALPSPPA-----SFPGQAPFSPSASL 511
Query: 182 RTPSLPTPPTREPKKVA--VVRTPPKSPSSAKSRL-QTAPVPMPD 223
L TPP + P +A +++ PP P+S + + P P PD
Sbjct: 512 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 556
Score = 38.5 bits (88), Expect = 0.011
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 7/79 (8%)
Query: 143 PAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRT 202
P+ TPP+ + PPS PP S +SP P S S TP PP + + +
Sbjct: 423 PSATPPS-QAPPSLAAPPLQVPPSPPASP-----PMSPSATPPPQAPPPLAAPPLQLAKP 476
Query: 203 PPKSPSS-AKSRLQTAPVP 220
PP++P + A LQ P P
Sbjct: 477 PPQAPPALATPPLQALPSP 495
Score = 28.9 bits (63), Expect = 8.9
Identities = 36/122 (29%), Positives = 52/122 (42%), Gaps = 24/122 (19%)
Query: 113 AKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKT----PPSSGEPPKSGDRSGY 168
A GA G+ +A G G AT IP P A T PP+SG ++
Sbjct: 49 AAGAVGRKPLAERAG-------GIGGAT-IPESAPRAGPTRTSRPPASGRGERAPPAKN- 99
Query: 169 SSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRT---------PPKSPSSAKSRLQTA-P 218
+SPG +PG S T + P P ++ +++ T P +S SA +R T+ P
Sbjct: 100 TSPGPVSSPGRASGT-TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP 158
Query: 219 VP 220
P
Sbjct: 159 TP 160
Score = 28.9 bits (63), Expect = 8.9
Identities = 26/103 (25%), Positives = 34/103 (33%), Gaps = 6/103 (5%)
Query: 122 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS 181
+ PR PG + R+ P P PP PP S S P G S +
Sbjct: 544 LQAPRRPPTPGPDTSVSGPRLTLALAPGP--PP----PPSRSPSSTLSGPDLAGHSSSAT 597
Query: 182 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL 224
TP P+ A PP + +A + P P L
Sbjct: 598 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 640
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 47.4 bits (111), Expect = 2e-05
Identities = 58/202 (28%), Positives = 87/202 (43%), Gaps = 27/202 (13%)
Query: 61 SETSDAKSTPTAE--AEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADG 118
S + D+K T ++ E +LE E Q + + ++ TG D+K +
Sbjct: 952 SHSLDSKPTVKSQWTLEVPSSSSCANLETERNSDPLQPQ--APRREITGWDEKALRSF-- 1007
Query: 119 KTKIATPRGA-APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP-----G 172
+ + +GA APP QKG + PA+T +P S E + G G+SSP G
Sbjct: 1008 -REFSGLKGAEAPPNQKGPSGVQPNPAET-----SPISLAEGKELGTHLGHSSPQIRQGG 1061
Query: 173 SPGTPGSRSRTPSL--PTPPTREPKKVAVVRT---PPKSPSSAKSRLQTAPVPMPDL--- 224
PG S+ +PS+ T P P K+ + T PPK + S +P+ DL
Sbjct: 1062 VPGPESSKESSPSVQDSTSPGEHPAKLQLKSTECGPPKGKNRPSSLNLDPAIPIADLFWF 1121
Query: 225 KNVKSKIGSTENLKHQPGGGKV 246
+NV S S +PG KV
Sbjct: 1122 ENVAS-FSSPGMQVSEPGDPKV 1142
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 673
Score = 47.0 bits (110), Expect = 3e-05
Identities = 55/190 (28%), Positives = 79/190 (41%), Gaps = 18/190 (9%)
Query: 67 KSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDG-TGSDDKKAK-GADGKTKIA- 123
+++PT A TPS T + S S TGS + G+ + +
Sbjct: 436 RASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTR 495
Query: 124 TPRGAAPPGQKGQANATRIPAKTPPA--PKTPPSSGEPPKSGDRSGYSSPGSPGTPG--S 179
TP A+ + A+ TR P++ P P T +G P + S TP S
Sbjct: 496 TPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRAS 555
Query: 180 RSRTPS---LPTPP----TREPKKVAVVRTPPK-SPSSAKSRLQTAPVPMPDLKNVKSKI 231
+RTPS L TP TR P V + R PP SP+ SR T+P MP + +K+
Sbjct: 556 LTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSR--TSPTGMPS-SALLTKM 612
Query: 232 GSTENLKHQP 241
ST ++ P
Sbjct: 613 DSTASITRTP 622
Score = 43.1 bits (100), Expect = 5e-04
Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 17/157 (10%)
Query: 66 AKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARM-VSKSKDGTGSDDKKAKGADGKTKIAT 124
++++PT + A TPS T + +S + TG+ + + T T
Sbjct: 345 SRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLT 404
Query: 125 --PRGAAPPGQKGQANATRIPAKTPPAPKTPP---SSGEPPKS--------GDRSGYSSP 171
P A+P G + + T++ + P +TPP +G PP++ +G S
Sbjct: 405 RKPPRASPTGMLSRTSITKMDSTASPT-RTPPRASPTGTPPRASPTGTPSRASPTGTQST 463
Query: 172 GSP-GTPGSRSRTPSLPT-PPTREPKKVAVVRTPPKS 206
SP G+P + S T S T PT P + ++ RTP ++
Sbjct: 464 ASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRA 500
Score = 38.9 bits (89), Expect = 0.009
Identities = 41/154 (26%), Positives = 61/154 (39%), Gaps = 27/154 (17%)
Query: 68 STPTAEAEEAGIGDTPSLED--EAAGHVTQARMVSKSK----DGTGSDDKKAKGADGKTK 121
++PT A + TPS + M+S++ D T S + A +
Sbjct: 284 ASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRA---SI 340
Query: 122 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSP-GTPGSR 180
TP A+P G+ A+ T P++ P P + +G SS SP GTP
Sbjct: 341 TRTPSRASPTGKPSTASPTGTPSRASPTGS--------PSTASLTGLSSTASPTGTPPRA 392
Query: 181 SRTPSLPTPPTREPKKVAVVRTPPK-SPSSAKSR 213
S PT P ++ R PP+ SP+ SR
Sbjct: 393 S--------PTGTPSTASLTRKPPRASPTGMLSR 418
Score = 31.2 bits (69), Expect = 1.8
Identities = 31/109 (28%), Positives = 41/109 (37%), Gaps = 11/109 (10%)
Query: 137 ANATRIPAKTPPA--PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 194
A TR P++ P P T +G P ++ S+ GTP S T TPP
Sbjct: 2 APPTRTPSRASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLT---GTPPRASL 58
Query: 195 KKVAVVRTPPKSPSSA------KSRLQTAPVPMPDLKNVKSKIGSTENL 237
K + + SPS A S L T M LK + + T L
Sbjct: 59 KGTTSMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTL 107
Score = 30.0 bits (66), Expect = 4.0
Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 15/105 (14%)
Query: 122 IATPRGAAPPGQKGQANATRIPA-----KTPPAPKTPPSSGEP--------PKSGDRSGY 168
I TP A+P G + + T++ + +TP P T +G P P +
Sbjct: 248 IRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRM 307
Query: 169 SSPGSPGTPGSRSRTPSLPTPP--TREPKKVAVVRTPPKSPSSAK 211
SP SR+ + + +R P + ++ RTP ++ + K
Sbjct: 308 LPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGK 352
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 47.0 bits (110), Expect = 3e-05
Identities = 38/115 (33%), Positives = 51/115 (44%), Gaps = 19/115 (16%)
Query: 124 TPRGAAPPGQKGQANATRIPAK-TPPAPKTPPSSGEPPKSGDRSGYSS--PGSPGTP--- 177
TP PP +K A PA PP+P TPP PP + + + P SP +P
Sbjct: 805 TPTPPVPPAKKQPA----FPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPS 860
Query: 178 ---GSRSRTPSLPTPPTRE--PKKVAVVRTPPKSPSSAKSRLQ----TAPVPMPD 223
S+ P PTPP E P K P+SP + K++ + + PVP PD
Sbjct: 861 VVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPD 915
Score = 37.0 bits (84), Expect = 0.033
Identities = 32/111 (28%), Positives = 44/111 (39%), Gaps = 5/111 (4%)
Query: 122 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSG-DRSGYSSPGSPGTPGSR 180
+ P PP G A A PA P AP P S PP + + + +P TP
Sbjct: 709 VPPPPPPPPPPTPGSAMAQLKPA--PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP 766
Query: 181 SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA-PVPMPDLKNVKSK 230
P+ P PP PK + + P + + A Q A P P P + K +
Sbjct: 767 PPIPA-PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ 816
Score = 37.0 bits (84), Expect = 0.033
Identities = 54/213 (25%), Positives = 76/213 (35%), Gaps = 32/213 (15%)
Query: 47 PLQTPTEDGSEEPGSETS-----DAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSK 101
P +PT D S PG +TS K P + I + E + +VSK
Sbjct: 944 PTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSK 1003
Query: 102 SKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPK 161
S G+ K + P AAPP + G+ N + + P + S + P
Sbjct: 1004 FTPPAES------GSPSKETLPPP--AAPP-KPGKLNLSGV--NLPGVLQQGCVSAKAPV 1052
Query: 162 SGDRSGYSSPGSPGTPGSRSRTP-----SLPTPPTREP--------KKVAVVRTPPKSPS 208
R S P P P LP PP P KVAVV P+ S
Sbjct: 1053 LSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWS 1112
Query: 209 SAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP 241
K ++ AP P +N +++ E + QP
Sbjct: 1113 --KMSVKKAPPPTRPKRNDSTRLTQAE-ISEQP 1142
Score = 35.8 bits (81), Expect = 0.073
Identities = 42/197 (21%), Positives = 71/197 (36%), Gaps = 44/197 (22%)
Query: 64 SDAKSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKS-----KDGTGSDDKKAKGADG 118
S + S P +++ + D+ + + AGHV +VS K GT ++ +
Sbjct: 538 SSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMES 597
Query: 119 --------------KTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGD 164
+ KI TP A+ P P PP P PP P +S
Sbjct: 598 MNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPP--PPPPPPPPPPPPPPPLPSQSAP 655
Query: 165 RSGYSSP------------GSPGTPGSRSRTPSLPTPPTREPKKVAVV-----------R 201
+G ++P + G+ + P+ P ++ K +V
Sbjct: 656 SAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPP 715
Query: 202 TPPKSPSSAKSRLQTAP 218
PP +P SA ++L+ AP
Sbjct: 716 PPPPTPGSAMAQLKPAP 732
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/103 (24%), Positives = 39/103 (37%), Gaps = 13/103 (12%)
Query: 112 KAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP 171
K K + +P PP + P+ P P PP + P + D+SG
Sbjct: 901 KPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASP--TPDKSG---- 954
Query: 172 GSPGTPGSRSRTPSLPTPPTREPKKVAVVRT------PPKSPS 208
SPG S++ +P PP + ++ + PK PS
Sbjct: 955 -SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPS 996
Score = 31.2 bits (69), Expect = 1.8
Identities = 27/110 (24%), Positives = 41/110 (37%), Gaps = 8/110 (7%)
Query: 141 RIPAKTPPAPKTPPSSGEP--PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVA 198
+I ++ PP P P +P P + + S P P + + +P+P P +
Sbjct: 864 QIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES 923
Query: 199 VVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGS---TENLKHQPGGGK 245
+ PP PS + P P P K GS + PGG K
Sbjct: 924 SLVFPPPPPSPVPA---PPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKK 970
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.126 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,409,539
Number of Sequences: 37866
Number of extensions: 1283865
Number of successful extensions: 16551
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 339
Number of HSP's successfully gapped in prelim test: 1468
Number of HSP's that attempted gapping in prelim test: 7332
Number of HSP's gapped (non-prelim): 6663
length of query: 412
length of database: 18,247,518
effective HSP length: 105
effective length of query: 307
effective length of database: 14,271,588
effective search space: 4381377516
effective search space used: 4381377516
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.