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Search of human proteins with 171906582
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|171906582 coiled-coil domain containing 47 [Homo sapiens]
(483 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|171906582 coiled-coil domain containing 47 [Homo sapiens] 967 0.0
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 50 3e-06
gi|55956788 nucleolin [Homo sapiens] 47 5e-05
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 47 5e-05
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 46 9e-05
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 46 9e-05
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 45 1e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 45 1e-04
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 45 1e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 45 2e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 45 2e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 45 2e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 45 2e-04
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa... 45 2e-04
gi|17975763 myelin transcription factor 1 [Homo sapiens] 44 3e-04
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 44 3e-04
gi|148746195 trichohyalin [Homo sapiens] 44 3e-04
gi|115529449 upstream binding transcription factor, RNA polymera... 44 3e-04
gi|115529451 upstream binding transcription factor, RNA polymera... 44 3e-04
gi|7657671 upstream binding transcription factor, RNA polymerase... 44 3e-04
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 44 3e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 43 6e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 43 6e-04
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 43 6e-04
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 43 6e-04
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 43 6e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 43 6e-04
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 43 6e-04
gi|12711676 UPF3 regulator of nonsense transcripts homolog A iso... 43 6e-04
gi|18375525 UPF3 regulator of nonsense transcripts homolog A iso... 43 6e-04
>gi|171906582 coiled-coil domain containing 47 [Homo sapiens]
Length = 483
Score = 967 bits (2501), Expect = 0.0
Identities = 483/483 (100%), Positives = 483/483 (100%)
Query: 1 MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIIT 60
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIIT
Sbjct: 1 MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIIT 60
Query: 61 EDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKDPI 120
EDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKDPI
Sbjct: 61 EDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKDPI 120
Query: 121 TIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT 180
TIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
Sbjct: 121 TIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT 180
Query: 181 LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRP 240
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRP
Sbjct: 181 LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRP 240
Query: 241 VSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLA 300
VSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLA
Sbjct: 241 VSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLA 300
Query: 301 ILSEMGEVTDGMMDTKMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLL 360
ILSEMGEVTDGMMDTKMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLL
Sbjct: 301 ILSEMGEVTDGMMDTKMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLL 360
Query: 361 FTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKL 420
FTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKL
Sbjct: 361 FTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKL 420
Query: 421 THVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKV 480
THVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKV
Sbjct: 421 THVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKV 480
Query: 481 KAM 483
KAM
Sbjct: 481 KAM 483
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 50.4 bits (119), Expect = 3e-06
Identities = 30/98 (30%), Positives = 55/98 (56%), Gaps = 6/98 (6%)
Query: 390 IDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKK-----RAEKERI 444
+ K K R RE K+K + R +E K +++ + RRE+++ +AEK+R+
Sbjct: 344 LGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRL 403
Query: 445 MNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKA 482
E E+Q L EA L ++KK E+K+++ ++ ++KA
Sbjct: 404 KEERRKERQEAL-EAKLEEKRKKEEEKRLREEEKRIKA 440
Score = 30.4 bits (67), Expect = 3.7
Identities = 22/84 (26%), Positives = 47/84 (55%), Gaps = 6/84 (7%)
Query: 403 KQKADKNRARVEENFLKLTHVQR----QEAAQSRREEKKRAEKERIMNEEDPEKQRRLEE 458
K +KN+ R++ + +L + +E + +EE KRA KE +++ EK+ + +E
Sbjct: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRA-KEEAKKKKEEEKELKEKE 385
Query: 459 AALRREQKKLEK-KQMKMKQIKVK 481
+RE+ + EK ++ ++K+ + K
Sbjct: 386 RREKREKDEKEKAEKQRLKEERRK 409
Score = 30.4 bits (67), Expect = 3.7
Identities = 20/92 (21%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQ-EAAQSRREEKKRAEKERIMNEED 449
+K ++ + ++ K+KA+K R + E + ++ + E + + EEK+ E+E+ + E
Sbjct: 383 EKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
Query: 450 PEKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
E R ++ + K L K ++K
Sbjct: 443 AEITRFFQKPKTPQAPKTLAGSCGKFAPFEIK 474
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 46.6 bits (109), Expect = 5e-05
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 31/138 (22%)
Query: 20 AKFDDFEDEEDIV----EYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQD 75
AK +D ++EED E DD D E ED +E + ++ +ED++DE + E D
Sbjct: 140 AKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDD 199
Query: 76 ENQEGD---------------------------FEDADTQEGDTESEPYDDEEFEGYEDK 108
+++E D ED D +E D + + DDE+ E +D+
Sbjct: 200 DDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDE 259
Query: 109 PDTSSSKNKDPITIVDVP 126
D + ++ + + P
Sbjct: 260 DDEEEEEEEEEEPVKEAP 277
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 3/95 (3%)
Query: 23 DDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDF 82
DD +DE+D + DD + E+ ME + + + + E +DE ++ +
Sbjct: 188 DDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVA---EDEDEEEDDED 244
Query: 83 EDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNK 117
ED D E D + + DDEE E E++ + K
Sbjct: 245 EDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGK 279
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 14/97 (14%)
Query: 16 SVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESP------QRVIITE-----DDE 64
+ + A + ED+ED + +D+D E +D E+++ +P +V+ + +DE
Sbjct: 177 AAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDE 236
Query: 65 DETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEE 101
DE E + +DE+ + D +D D + D E E ++EE
Sbjct: 237 DE---EEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEE 270
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 46.6 bits (109), Expect = 5e-05
Identities = 27/87 (31%), Positives = 52/87 (59%), Gaps = 7/87 (8%)
Query: 390 IDKAKKFRLNREG-KQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEE 448
++K ++ RL RE K+KA++ R R+EE ++QE + R+EE+K+ ++ +
Sbjct: 423 VEKEEQDRLEREELKRKAEEERLRLEEE------ARKQEEERKRQEEEKKKQEGEEKRKA 476
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKM 475
E +R+ EE L +E+++ EK++ M
Sbjct: 477 GEEAKRKAEEELLLKEKQEQEKQEKAM 503
Score = 38.9 bits (89), Expect = 0.011
Identities = 27/73 (36%), Positives = 44/73 (60%), Gaps = 4/73 (5%)
Query: 406 ADKNR-ARVEENFLKLTHVQRQEAAQSRREEKKR-AEKERIMNEEDPEKQRRLEEAALRR 463
A+K R AR+++ + V+++E + REE KR AE+ER+ EE+ KQ EE +
Sbjct: 405 AEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQE--EERKRQE 462
Query: 464 EQKKLEKKQMKMK 476
E+KK ++ + K K
Sbjct: 463 EEKKKQEGEEKRK 475
Score = 36.6 bits (83), Expect = 0.052
Identities = 23/65 (35%), Positives = 38/65 (58%), Gaps = 7/65 (10%)
Query: 420 LTHVQRQEAAQSRREEKKRAEKE---RIMNEE----DPEKQRRLEEAALRREQKKLEKKQ 472
L +RQ Q +EE++R EKE R+ EE E++ RLEE A ++E+++ +++
Sbjct: 404 LAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEE 463
Query: 473 MKMKQ 477
K KQ
Sbjct: 464 EKKKQ 468
Score = 33.5 bits (75), Expect = 0.44
Identities = 24/79 (30%), Positives = 44/79 (55%), Gaps = 18/79 (22%)
Query: 415 ENFLKLTHVQRQEAAQSRREEKKR---AEKERIMNEED----------PEKQRRLEEAAL 461
E FLK +RQ A+ RREE+++ A +++I+ ++ E+ R+LEE
Sbjct: 46 EGFLKSD--ERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQ 103
Query: 462 RREQKKL---EKKQMKMKQ 477
R +QK+ EK++ K+++
Sbjct: 104 REDQKRAAVEEKRKQKLRE 122
Score = 31.2 bits (69), Expect = 2.2
Identities = 22/91 (24%), Positives = 47/91 (51%), Gaps = 11/91 (12%)
Query: 397 RLNREGKQKADKNRARVEENFL------KLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
RL +E +++ +K A E+ L +L + ++ E + EE+++ E ++ E+
Sbjct: 56 RLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEK 115
Query: 451 EKQRRLE-----EAALRREQKKLEKKQMKMK 476
KQ+ E EA +RR ++ ++ ++K K
Sbjct: 116 RKQKLREEEERLEAMMRRSLERTQQLELKKK 146
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 45.8 bits (107), Expect = 9e-05
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEK--KRAEKERIMNEED 449
K KK R RE + K + R R + K +++E + +RE K KR ++ER E
Sbjct: 115 KKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRER 174
Query: 450 PEKQRRLE-EAALRREQKKLEKKQMKMKQIKVK 481
K+R+ E E RRE+KK KK+ + K+ + K
Sbjct: 175 NRKERKKERERKERRERKKERKKERRKKKERKK 207
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRR-----EEKKRAEKERIMNEE 448
K+ R +E K++ + R + E K QR+E + R E+KKR K+R E
Sbjct: 55 KRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRER 114
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
+K+R+ E ++ +++ KK+ K K+ K
Sbjct: 115 KKKKERKERERENKQRRERKRKKRRKKKRRK 145
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/94 (28%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKK---RAEKERIMNE 447
++ K+ R+ ++K K R E K +R+ + RRE KK R E+ER N+
Sbjct: 70 ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERER-ENK 128
Query: 448 EDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
+ E++R+ RR+++K EK++ K ++ + K
Sbjct: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLK-LTHVQRQEAAQSRREEKKR-----AEKERIM 445
K KK + RE KQ+ + R + +E + + QR+E + +R +KKR EKER
Sbjct: 96 KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK 155
Query: 446 NEEDPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
E +K+++ E R +K KK+ + K+
Sbjct: 156 RERKRKKRKKEEREKKRERNRKERKKERERKE 187
Score = 40.8 bits (94), Expect = 0.003
Identities = 25/88 (28%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Query: 392 KAKKFRLNRE-GKQKADKNRARVEENFLKLTHVQRQEAAQSR-REEKKRAEKERIMNEED 449
K KK R RE GK++ K + R ++ + +R+ + + RE K+R +ER +E
Sbjct: 61 KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120
Query: 450 PEKQRRLEEAALRREQKKLEKKQMKMKQ 477
E++R ++ R+ +K+ +KK+ K ++
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERK 148
Score = 39.3 bits (90), Expect = 0.008
Identities = 21/82 (25%), Positives = 44/82 (53%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEA 459
R+ +++ + R R E K ++++ + +RE K E++R E+ +++R E
Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95
Query: 460 ALRREQKKLEKKQMKMKQIKVK 481
++E+KK E+KQ ++ K K
Sbjct: 96 KRKKEKKKRERKQRGRRERKKK 117
Score = 37.7 bits (86), Expect = 0.023
Identities = 17/77 (22%), Positives = 42/77 (54%)
Query: 403 KQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALR 462
++++++ + R E K + ++ + ++E+KKR ++ER E K+R + R
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 463 REQKKLEKKQMKMKQIK 479
++++ KK+ K ++ K
Sbjct: 91 EKERRKRKKEKKKRERK 107
Score = 37.4 bits (85), Expect = 0.031
Identities = 20/86 (23%), Positives = 43/86 (50%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
+K R GK++ K + R + +R++ + RRE+++R K+ E ++
Sbjct: 51 EKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRG 110
Query: 454 RRLEEAALRREQKKLEKKQMKMKQIK 479
RR + R++++ E KQ + ++ K
Sbjct: 111 RRERKKKKERKERERENKQRRERKRK 136
Score = 36.2 bits (82), Expect = 0.068
Identities = 22/91 (24%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNE---E 448
K ++ R R+ +++ ++ R R ++ K +R + + +R+E+++ KER E
Sbjct: 38 KERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKR 97
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
EK++R + RRE+KK ++++ + ++ K
Sbjct: 98 KKEKKKRERKQRGRRERKKKKERKERERENK 128
Score = 34.3 bits (77), Expect = 0.26
Identities = 20/74 (27%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Query: 391 DKAKKFRLNREGKQKADKNRA-RVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEED 449
++ +K R E ++K ++NR R +E K +++E + RR++K+R + + + D
Sbjct: 157 ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTD 216
Query: 450 PEKQRRLEEAALRR 463
+ R L E+A R
Sbjct: 217 SQVFRPLRESAFNR 230
Score = 33.1 bits (74), Expect = 0.58
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 7/83 (8%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPE 451
+ K+ + R ++K +K R + E K +R++ + R+E+K+ E+ER + +
Sbjct: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK-ERER-KERRERK 192
Query: 452 KQRRLEEAALRREQKKLEKKQMK 474
K+R+ E R +KK KK K
Sbjct: 193 KERKKE-----RRKKKERKKDRK 210
Score = 30.8 bits (68), Expect = 2.9
Identities = 17/77 (22%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 405 KADKNRARVEEN----FLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAA 460
KA +RA V+ N + +H+ + + +K+R E+E+ E + E++R +
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKE 62
Query: 461 LRREQKKLEKKQMKMKQ 477
++ +K+ K+ + K+
Sbjct: 63 KKKRKKRERGKERERKR 79
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 45.8 bits (107), Expect = 9e-05
Identities = 35/121 (28%), Positives = 60/121 (49%), Gaps = 23/121 (19%)
Query: 368 SGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQE 427
+G T P++ LL A+K RL RE ++K ++ R EE L +R+E
Sbjct: 471 AGTTDPEEATRLL------------AEKRRLAREQREKEERERREQEE----LERQKREE 514
Query: 428 AAQ-------SRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKV 480
AQ +RREE+ R + E++ + QR+ EE ALR ++ ++ K ++ +V
Sbjct: 515 LAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARV 574
Query: 481 K 481
+
Sbjct: 575 R 575
Score = 35.0 bits (79), Expect = 0.15
Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 8/87 (9%)
Query: 393 AKKFRLNREGKQKADKNRARVEENFLKLTHVQRQ--EAAQSRREEKKRAEKE-----RIM 445
A++ R +++ + R E+ K +QRQ E A REE +RA+++ R+
Sbjct: 516 AQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVR 575
Query: 446 NEEDPEKQRRLEEAALRREQKKLEKKQ 472
E + +Q R E+ R EQ++LE+K+
Sbjct: 576 EEAERVRQER-EKHFQREEQERLERKK 601
Score = 33.9 bits (76), Expect = 0.34
Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 398 LNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPE-KQRRL 456
+N K EE L +R Q +EE++R E+E + ++ E QR
Sbjct: 461 VNASASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVA 520
Query: 457 EEAALRREQ--KKLEKKQMKMKQ 477
EE RRE+ ++LE +Q + K+
Sbjct: 521 EERTTRREEESRRLEAEQAREKE 543
Score = 32.3 bits (72), Expect = 0.99
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 10/85 (11%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRRE-EKKRAEKERIMNEEDP 450
+ K+ +L R+ +++A + R E Q++E A+ R E E+ R E+E+ E+
Sbjct: 540 REKEEQLQRQAEERALREREEAER-----AQRQKEEEARVREEAERVRQEREKHFQREEQ 594
Query: 451 ---EKQRRLEEAALR-REQKKLEKK 471
E+++RLEE R R + +KK
Sbjct: 595 ERLERKKRLEEIMKRTRRTEATDKK 619
Score = 32.0 bits (71), Expect = 1.3
Identities = 19/76 (25%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRL 456
RL RE +++ +K A E + ++R+E A+ E+ K+R+ + E++RR
Sbjct: 68 RLARERREEREKQLAARE-----IVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRA 122
Query: 457 EEAALRREQKKLEKKQ 472
RR++ + +K++
Sbjct: 123 AVEEKRRQRLEEDKER 138
Score = 31.6 bits (70), Expect = 1.7
Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 11/78 (14%)
Query: 401 EGKQKADKNRARVEENFLKLTHVQRQEA--AQSRREEKKRA--EKERIMNEEDPEKQRRL 456
+ ++K ++ + + EE L+ +R+EA AQ ++EE+ R E ER+ E + QR
Sbjct: 538 QAREKEEQLQRQAEERALR----EREEAERAQRQKEEEARVREEAERVRQEREKHFQREE 593
Query: 457 EEAALRREQKKLEKKQMK 474
+E R E+KK ++ MK
Sbjct: 594 QE---RLERKKRLEEIMK 608
Score = 29.6 bits (65), Expect = 6.4
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 425 RQEAAQSRREEK-KRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMK 474
RQ A+ RREE+ K+ I+ E E+ R+ E L +K+LE+++ K
Sbjct: 66 RQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQK 116
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 45.4 bits (106), Expect = 1e-04
Identities = 23/87 (26%), Positives = 49/87 (56%), Gaps = 1/87 (1%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
+K ++ R ++EGK++ K + EE + + +E + R+E KKR E++++ +E+
Sbjct: 119 EKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKR-ERKQVGEKEEE 177
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
K++ +E R +K KK+ + K+
Sbjct: 178 RKEKERKERKKRERNRKERKKERERKE 204
Score = 43.1 bits (100), Expect = 6e-04
Identities = 24/81 (29%), Positives = 44/81 (54%), Gaps = 9/81 (11%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
KK R +E K+ +K + + +E ++E ++ +E K+R KE EE E++
Sbjct: 98 KKRRREKENKEGEEKEKRKKKE---------KKERGRTSKEGKERERKEERKREERKERE 148
Query: 454 RRLEEAALRREQKKLEKKQMK 474
R+ EE RE+K+ +K++ K
Sbjct: 149 RKKEEREKERERKERKKRERK 169
Score = 43.1 bits (100), Expect = 6e-04
Identities = 27/87 (31%), Positives = 49/87 (56%), Gaps = 11/87 (12%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAE-KERIMNEEDP 450
K ++ + N+EG++K + + +E ++ + R+EE+KR E KER +E+
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKER----GRTSKEGKERERKEERKREERKERERKKEER 154
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
EK+R R+E+KK E+KQ+ K+
Sbjct: 155 EKERE------RKERKKRERKQVGEKE 175
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 6/92 (6%)
Query: 391 DKAKKFRLNREGK-QKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEED 449
++ ++ R RE K ++ +K R R E + V +E + +E K+R ++ER N ++
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER--NRKE 195
Query: 450 PEKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
+K+R +E RRE+KK KK+ + K+ + K
Sbjct: 196 RKKERERKE---RRERKKERKKKEERKKERQK 224
Score = 38.9 bits (89), Expect = 0.011
Identities = 19/54 (35%), Positives = 31/54 (57%)
Query: 424 QRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
+R+ ++R+E KK E ER + EK++R E +RE+ K EKK + K+
Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
Score = 37.4 bits (85), Expect = 0.031
Identities = 20/87 (22%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ ++ +EGK++ + R + K + +E + R +++K+ E+++ EE
Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK---EERE 96
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
K+RR E+ E+K+ KK+ K ++
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKER 123
Score = 35.8 bits (81), Expect = 0.089
Identities = 26/84 (30%), Positives = 45/84 (53%), Gaps = 6/84 (7%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
KK R RE K+K ++ + R E K +R++ + R +K+R EKE N+E EK+
Sbjct: 60 KKERRERE-KRKREREKERKRERGKKEKKGERKK--EERERKKRRREKE---NKEGEEKE 113
Query: 454 RRLEEAALRREQKKLEKKQMKMKQ 477
+R ++ R + E K+ + K+
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKE 137
Score = 35.4 bits (80), Expect = 0.12
Identities = 19/78 (24%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEA 459
R+ K+K ++ R E + +++E + R +K+ EKER ++ +K+ R +
Sbjct: 115 RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER--ERKERKKRERKQVG 172
Query: 460 ALRREQKKLEKKQMKMKQ 477
E+K+ E+K+ K ++
Sbjct: 173 EKEEERKEKERKERKKRE 190
Score = 35.4 bits (80), Expect = 0.12
Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFL--KLTHVQRQEAAQSRREEKKRAEKERIMNEE 448
++ +K R RE KQ +K R E+ K R+E + R +++R K+ +E
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216
Query: 449 DPEKQRRLEEAALRREQK--KLEKKQMK 474
+ +K+R+ + RE++ K E+K+ K
Sbjct: 217 ERKKERQKDRQTNWREKERGKRERKERK 244
Score = 34.7 bits (78), Expect = 0.20
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
+K R GK++ R + E K + + + + + KK+ +KER ++ +++
Sbjct: 74 EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
Query: 454 RRLEEAALRREQKKLEKKQ 472
R EE R E+K+ E+K+
Sbjct: 134 ERKEERK-REERKERERKK 151
Score = 33.9 bits (76), Expect = 0.34
Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
Query: 425 RQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRR--EQKKLEKKQMKMKQIK 479
R+E + R E+K+ +ER + + EK+R+ E + E+KK E+++ K ++ K
Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREK 104
Score = 31.6 bits (70), Expect = 1.7
Identities = 18/70 (25%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
Query: 401 EGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAA 460
E K+K K R + E N + + ++ + R++E+K+ E+ + ++D + R +E
Sbjct: 177 ERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERG 236
Query: 461 LRREQKKLEK 470
+RE+K+ +K
Sbjct: 237 -KRERKERKK 245
Score = 29.3 bits (64), Expect = 8.3
Identities = 20/85 (23%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 402 GKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKR-----AEKERIMNEEDPEKQRRL 456
G Q + R R E + + E + RRE +KR E++R +++ + +R+
Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
Query: 457 EEAALRREQKKLEKKQMKMKQIKVK 481
EE ++ +++ E K+ + K+ + K
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKK 117
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/91 (28%), Positives = 50/91 (54%), Gaps = 8/91 (8%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
+K K+ R +E K+K + R E+ + +E + R+ +KK+ E+ER EE+
Sbjct: 31 EKRKEKRKEKEKKKKTKETEKRKEK--------EEEEKKRKRKRKKKKEEEEREEEEEEE 82
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
E+++ EE R +KK +K++ K ++ + K
Sbjct: 83 EEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/90 (27%), Positives = 48/90 (53%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPE 451
K K+ ++ K K + R EE K ++++ + REE++ E+E EE E
Sbjct: 34 KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93
Query: 452 KQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
+RR ++ RR++++ EKK+ + ++ K K
Sbjct: 94 GRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 43.9 bits (102), Expect = 3e-04
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
+K KK + + K+K ++ + R + K +R+E + EEK+ EKE +
Sbjct: 41 EKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMK 476
+K+RR EE E+KK +++ K K
Sbjct: 101 KKRRRKEE---EEEKKKKRRRKTKKK 123
Score = 38.5 bits (88), Expect = 0.014
Identities = 20/76 (26%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 405 KADKNRARVEENFLKLTHVQRQEAAQSRREEK---KRAEKERIMNEEDPEKQRRLEEAAL 461
K K + + E + + +E + +R+EK KR EKE+ ++ EK++ EE
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 462 RREQKKLEKKQMKMKQ 477
+R++K+ +KK+ + ++
Sbjct: 61 KRKRKRKKKKEEEERE 76
Score = 33.9 bits (76), Expect = 0.34
Identities = 17/79 (21%), Positives = 41/79 (51%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
KK + +E ++ + EE +R+E + + ++KK E E+ +E+ EK+
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 454 RRLEEAALRREQKKLEKKQ 472
R+ + + E+++ E+++
Sbjct: 62 RKRKRKKKKEEEEREEEEE 80
Score = 31.6 bits (70), Expect = 1.7
Identities = 14/58 (24%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 424 QRQEAAQSRREEKKRAEKERIMNE--EDPEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
+ +E ++ EE+K +++ E ++ EK+++ +E R+E+++ EKK+ + ++ K
Sbjct: 12 ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKK 69
Score = 31.2 bits (69), Expect = 2.2
Identities = 15/47 (31%), Positives = 28/47 (59%)
Query: 435 EKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
+KK+ +K+ E+ E+ EE +R++K+ EK++ K K+ K K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTK 47
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/94 (34%), Positives = 56/94 (59%), Gaps = 10/94 (10%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQE--AAQSRREEKKRAEKE---RIMNEE 448
+K + RE ++ ++ + +E+ L+ QRQ AAQ REE++RA++E RI+ E
Sbjct: 149 RKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEEN 208
Query: 449 D---PEKQRRLEEAALR--REQKKLEKKQMKMKQ 477
+ E Q +L E LR EQ+K+ +++MK++Q
Sbjct: 209 NRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQ 242
Score = 33.1 bits (74), Expect = 0.58
Identities = 21/57 (36%), Positives = 35/57 (61%), Gaps = 9/57 (15%)
Query: 430 QSRREEKKRAEKER---IMNEEDPEK------QRRLEEAALRREQKKLEKKQMKMKQ 477
Q R EE+K+AE ER I +E EK RR+EE +R +++LEK++ ++++
Sbjct: 99 QKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIER 155
Score = 33.1 bits (74), Expect = 0.58
Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 393 AKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRR--EEKKRAEKERIMNEEDP 450
A+K R E ++ + R +EEN K+ Q + A + R EE+++ +ER+ E++
Sbjct: 186 AQKAREEEERAKREELERI-LEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQER 244
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMK 476
++Q++ E+ + + K K +K
Sbjct: 245 QRQQKEEQKIILGKGKSRPKLSFSLK 270
Score = 30.0 bits (66), Expect = 4.9
Identities = 28/100 (28%), Positives = 53/100 (53%), Gaps = 13/100 (13%)
Query: 389 SIDKAKKFRLNREGKQKADKNRAR------VEENFLKLTHVQRQEAAQSRREEKKRAEKE 442
S+D+ +K E ++KA+ R R +EE ++ +R E ++R E+ E E
Sbjct: 94 SLDEKQK---REEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEE---ELE 147
Query: 443 RIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKA 482
+ +E + E RR+EEA E++ LE+ + + +Q ++ A
Sbjct: 148 KRKDEIEREVLRRVEEAKRIMEKQLLEELE-RQRQAELAA 186
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/93 (30%), Positives = 57/93 (61%), Gaps = 6/93 (6%)
Query: 387 IYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRR---EEKKRAEKER 443
+ ++KAK +L +E +++A+ R EE + ++RQ+ RR EE+KR E+E
Sbjct: 720 LQQLEKAKAAKLEQE-RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEE 778
Query: 444 I--MNEEDPEKQRRLEEAALRREQKKLEKKQMK 474
+ +E+ +++R +E ALRR++++ E++Q +
Sbjct: 779 LARRKQEEALRRQREQEIALRRQREEEERQQQE 811
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/89 (29%), Positives = 52/89 (58%), Gaps = 12/89 (13%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKE-RIMNEED 449
+ AK R E +++ ++NR R+EE EAA+ R EE++R KE + +++
Sbjct: 840 EAAKWAREEEEAQRRLEENRLRMEE-----------EAARLRHEEEERKRKELEVQRQKE 888
Query: 450 PEKQRRLEEAALRREQKKLEKKQMKMKQI 478
+QR+ ++ ALRR Q++ +++Q+ ++
Sbjct: 889 LMRQRQQQQEALRRLQQQQQQQQLAQMKL 917
Score = 42.7 bits (99), Expect = 7e-04
Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 25/103 (24%)
Query: 398 LNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNE---------- 447
L R+ +Q+ R R EE Q+QE A R EE++R E+ER E
Sbjct: 788 LRRQREQEIALRRQREEEER------QQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
Query: 448 -----EDPEKQRRLEEAALRREQK----KLEKKQMKMKQIKVK 481
E+ E QRRLEE LR E++ + E+++ K K+++V+
Sbjct: 842 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 884
Score = 37.4 bits (85), Expect = 0.031
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 8/87 (9%)
Query: 401 EGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEK---KRAEKERIMNEEDPEKQRRLE 457
E +++ ++ R + EE L Q +EAA+ REE+ +R E+ R+ EE+ + R E
Sbjct: 818 EERRREEEERRKQEE----LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 873
Query: 458 EAALRRE-QKKLEKKQMKMKQIKVKAM 483
E R+E + + +K+ M+ +Q + +A+
Sbjct: 874 EERKRKELEVQRQKELMRQRQQQQEAL 900
Score = 32.7 bits (73), Expect = 0.75
Identities = 23/94 (24%), Positives = 54/94 (57%), Gaps = 8/94 (8%)
Query: 389 SIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKK-RAEKE--RIM 445
++ + ++ R E ++K ++ + EE K + +E AQ R EE + R E+E R+
Sbjct: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWA--REEEEAQRRLEENRLRMEEEAARLR 870
Query: 446 NEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
+EE+ K++ LE ++R+++ + ++Q + + ++
Sbjct: 871 HEEEERKRKELE---VQRQKELMRQRQQQQEALR 901
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/93 (30%), Positives = 57/93 (61%), Gaps = 6/93 (6%)
Query: 387 IYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRR---EEKKRAEKER 443
+ ++KAK +L +E +++A+ R EE + ++RQ+ RR EE+KR E+E
Sbjct: 747 LQQLEKAKAAKLEQE-RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEE 805
Query: 444 I--MNEEDPEKQRRLEEAALRREQKKLEKKQMK 474
+ +E+ +++R +E ALRR++++ E++Q +
Sbjct: 806 LARRKQEEALRRQREQEIALRRQREEEERQQQE 838
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/89 (29%), Positives = 52/89 (58%), Gaps = 12/89 (13%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKE-RIMNEED 449
+ AK R E +++ ++NR R+EE EAA+ R EE++R KE + +++
Sbjct: 867 EAAKWAREEEEAQRRLEENRLRMEE-----------EAARLRHEEEERKRKELEVQRQKE 915
Query: 450 PEKQRRLEEAALRREQKKLEKKQMKMKQI 478
+QR+ ++ ALRR Q++ +++Q+ ++
Sbjct: 916 LMRQRQQQQEALRRLQQQQQQQQLAQMKL 944
Score = 42.7 bits (99), Expect = 7e-04
Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 25/103 (24%)
Query: 398 LNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNE---------- 447
L R+ +Q+ R R EE Q+QE A R EE++R E+ER E
Sbjct: 815 LRRQREQEIALRRQREEEER------QQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868
Query: 448 -----EDPEKQRRLEEAALRREQK----KLEKKQMKMKQIKVK 481
E+ E QRRLEE LR E++ + E+++ K K+++V+
Sbjct: 869 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 911
Score = 37.4 bits (85), Expect = 0.031
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 8/87 (9%)
Query: 401 EGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEK---KRAEKERIMNEEDPEKQRRLE 457
E +++ ++ R + EE L Q +EAA+ REE+ +R E+ R+ EE+ + R E
Sbjct: 845 EERRREEEERRKQEE----LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 900
Query: 458 EAALRRE-QKKLEKKQMKMKQIKVKAM 483
E R+E + + +K+ M+ +Q + +A+
Sbjct: 901 EERKRKELEVQRQKELMRQRQQQQEAL 927
Score = 32.7 bits (73), Expect = 0.75
Identities = 23/94 (24%), Positives = 54/94 (57%), Gaps = 8/94 (8%)
Query: 389 SIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKK-RAEKE--RIM 445
++ + ++ R E ++K ++ + EE K + +E AQ R EE + R E+E R+
Sbjct: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWA--REEEEAQRRLEENRLRMEEEAARLR 897
Query: 446 NEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
+EE+ K++ LE ++R+++ + ++Q + + ++
Sbjct: 898 HEEEERKRKELE---VQRQKELMRQRQQQQEALR 928
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/93 (30%), Positives = 57/93 (61%), Gaps = 6/93 (6%)
Query: 387 IYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRR---EEKKRAEKER 443
+ ++KAK +L +E +++A+ R EE + ++RQ+ RR EE+KR E+E
Sbjct: 726 LQQLEKAKAAKLEQE-RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEE 784
Query: 444 I--MNEEDPEKQRRLEEAALRREQKKLEKKQMK 474
+ +E+ +++R +E ALRR++++ E++Q +
Sbjct: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQE 817
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/89 (29%), Positives = 52/89 (58%), Gaps = 12/89 (13%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKE-RIMNEED 449
+ AK R E +++ ++NR R+EE EAA+ R EE++R KE + +++
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEE-----------EAARLRHEEEERKRKELEVQRQKE 894
Query: 450 PEKQRRLEEAALRREQKKLEKKQMKMKQI 478
+QR+ ++ ALRR Q++ +++Q+ ++
Sbjct: 895 LMRQRQQQQEALRRLQQQQQQQQLAQMKL 923
Score = 42.7 bits (99), Expect = 7e-04
Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 25/103 (24%)
Query: 398 LNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNE---------- 447
L R+ +Q+ R R EE Q+QE A R EE++R E+ER E
Sbjct: 794 LRRQREQEIALRRQREEEER------QQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
Query: 448 -----EDPEKQRRLEEAALRREQK----KLEKKQMKMKQIKVK 481
E+ E QRRLEE LR E++ + E+++ K K+++V+
Sbjct: 848 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
Score = 37.4 bits (85), Expect = 0.031
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 8/87 (9%)
Query: 401 EGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEK---KRAEKERIMNEEDPEKQRRLE 457
E +++ ++ R + EE L Q +EAA+ REE+ +R E+ R+ EE+ + R E
Sbjct: 824 EERRREEEERRKQEE----LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 879
Query: 458 EAALRRE-QKKLEKKQMKMKQIKVKAM 483
E R+E + + +K+ M+ +Q + +A+
Sbjct: 880 EERKRKELEVQRQKELMRQRQQQQEAL 906
Score = 32.7 bits (73), Expect = 0.75
Identities = 23/94 (24%), Positives = 54/94 (57%), Gaps = 8/94 (8%)
Query: 389 SIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKK-RAEKE--RIM 445
++ + ++ R E ++K ++ + EE K + +E AQ R EE + R E+E R+
Sbjct: 819 ALRRLEERRREEEERRKQEELLRKQEEEAAKWA--REEEEAQRRLEENRLRMEEEAARLR 876
Query: 446 NEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
+EE+ K++ LE ++R+++ + ++Q + + ++
Sbjct: 877 HEEEERKRKELE---VQRQKELMRQRQQQQEALR 907
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/93 (30%), Positives = 57/93 (61%), Gaps = 6/93 (6%)
Query: 387 IYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRR---EEKKRAEKER 443
+ ++KAK +L +E +++A+ R EE + ++RQ+ RR EE+KR E+E
Sbjct: 726 LQQLEKAKAAKLEQE-RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEE 784
Query: 444 I--MNEEDPEKQRRLEEAALRREQKKLEKKQMK 474
+ +E+ +++R +E ALRR++++ E++Q +
Sbjct: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQE 817
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/89 (29%), Positives = 52/89 (58%), Gaps = 12/89 (13%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKE-RIMNEED 449
+ AK R E +++ ++NR R+EE EAA+ R EE++R KE + +++
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEE-----------EAARLRHEEEERKRKELEVQRQKE 894
Query: 450 PEKQRRLEEAALRREQKKLEKKQMKMKQI 478
+QR+ ++ ALRR Q++ +++Q+ ++
Sbjct: 895 LMRQRQQQQEALRRLQQQQQQQQLAQMKL 923
Score = 42.7 bits (99), Expect = 7e-04
Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 25/103 (24%)
Query: 398 LNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNE---------- 447
L R+ +Q+ R R EE Q+QE A R EE++R E+ER E
Sbjct: 794 LRRQREQEIALRRQREEEER------QQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
Query: 448 -----EDPEKQRRLEEAALRREQK----KLEKKQMKMKQIKVK 481
E+ E QRRLEE LR E++ + E+++ K K+++V+
Sbjct: 848 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 890
Score = 37.4 bits (85), Expect = 0.031
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 8/87 (9%)
Query: 401 EGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEK---KRAEKERIMNEEDPEKQRRLE 457
E +++ ++ R + EE L Q +EAA+ REE+ +R E+ R+ EE+ + R E
Sbjct: 824 EERRREEEERRKQEE----LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEE 879
Query: 458 EAALRRE-QKKLEKKQMKMKQIKVKAM 483
E R+E + + +K+ M+ +Q + +A+
Sbjct: 880 EERKRKELEVQRQKELMRQRQQQQEAL 906
Score = 32.7 bits (73), Expect = 0.75
Identities = 23/94 (24%), Positives = 54/94 (57%), Gaps = 8/94 (8%)
Query: 389 SIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKK-RAEKE--RIM 445
++ + ++ R E ++K ++ + EE K + +E AQ R EE + R E+E R+
Sbjct: 819 ALRRLEERRREEEERRKQEELLRKQEEEAAKWA--REEEEAQRRLEENRLRMEEEAARLR 876
Query: 446 NEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
+EE+ K++ LE ++R+++ + ++Q + + ++
Sbjct: 877 HEEEERKRKELE---VQRQKELMRQRQQQQEALR 907
>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
sapiens]
Length = 528
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/64 (35%), Positives = 39/64 (60%), Gaps = 2/64 (3%)
Query: 404 QKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRR 463
+K ++ + R EE + + +E Q E+++R E+ER+ EE E++RR+EE LR
Sbjct: 182 EKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREE--EERRRIEEERLRL 239
Query: 464 EQKK 467
EQ+K
Sbjct: 240 EQQK 243
Score = 43.5 bits (101), Expect = 4e-04
Identities = 22/67 (32%), Positives = 47/67 (70%), Gaps = 6/67 (8%)
Query: 423 VQRQEAAQSRREE---KKRAEKERIMNEEDPEKQRRLEEAALRREQ---KKLEKKQMKMK 476
++++E + R+EE ++R E+ER +++ EK+RR EE LRRE+ +++E+++++++
Sbjct: 181 IEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREEEERRRIEEERLRLE 240
Query: 477 QIKVKAM 483
Q K + M
Sbjct: 241 QQKQQIM 247
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 44.3 bits (103), Expect = 3e-04
Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 3/90 (3%)
Query: 26 EDEEDIVEYDDNDFAEF-EDVMEDSVTE--SPQRVIITEDDEDETTVELEGQDENQEGDF 82
ED E++VE + +ED+ +E S Q+ I++ ++EDE E E ++E E +
Sbjct: 219 EDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEE 278
Query: 83 EDADTQEGDTESEPYDDEEFEGYEDKPDTS 112
E+ + +E + E E ++EE E E++ + +
Sbjct: 279 EEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
Score = 33.1 bits (74), Expect = 0.58
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 15/101 (14%)
Query: 15 GSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQ 74
G +S + D+ E+EE+ E +D + E E+ E+ E++E+E E E +
Sbjct: 253 GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEE------------EEEEEEEEEEEEEE 300
Query: 75 DENQEGDFEDADTQEGDTESEPYDDEEFEGYED---KPDTS 112
+E +E D QE + + E G E KP+ S
Sbjct: 301 EEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYS 341
Score = 30.8 bits (68), Expect = 2.9
Identities = 14/52 (26%), Positives = 28/52 (53%)
Query: 420 LTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKK 471
L+H + E + EE++ E+E EE+ E++ EE E+++ E++
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 29.6 bits (65), Expect = 6.4
Identities = 15/58 (25%), Positives = 32/58 (55%)
Query: 425 RQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKA 482
+Q+ S EE + E+E EED E++ EE E+++ E+++ + ++ + +A
Sbjct: 250 KQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEA 307
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/101 (30%), Positives = 57/101 (56%), Gaps = 11/101 (10%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEED-- 449
+A+ L +E + + K +A+VEEN L Q+QE R+EEK + +E+I +E+
Sbjct: 252 QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKI 311
Query: 450 ---PEKQRRLE------EAALRREQKKLEKKQMKMKQIKVK 481
EK RR E E +RR+++ + +K+ K+++++ K
Sbjct: 312 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/85 (31%), Positives = 49/85 (57%), Gaps = 7/85 (8%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRL 456
RLN++ ++K + +++E K +Q QE +EEK R ++E + +E EK RR
Sbjct: 281 RLNQQQEEKMWRQEEKIQEREEK---IQEQEEKIREQEEKMRRQEEMMWEKE--EKMRRQ 335
Query: 457 EEAALRREQK--KLEKKQMKMKQIK 479
EE +E+K +LE+K + ++I+
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQEKIR 360
Score = 38.5 bits (88), Expect = 0.014
Identities = 22/103 (21%), Positives = 53/103 (51%), Gaps = 18/103 (17%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEE-------- 448
+++ + K + + + + EE + Q QEA R+EEK R ++E+I +E
Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411
Query: 449 ----------DPEKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
+ E++ + +E +RR+++K+ +++ K+++ + K
Sbjct: 412 KMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK 454
Score = 38.1 bits (87), Expect = 0.018
Identities = 22/87 (25%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ +K R E ++ +K EE + + +++ + +E+K E+E M E++
Sbjct: 485 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE- 543
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
EK RR EE +R ++ +L +++ KM++
Sbjct: 544 EKMRRQEE-KMREQEVRLRQQEEKMQE 569
Score = 37.0 bits (84), Expect = 0.040
Identities = 20/91 (21%), Positives = 51/91 (56%), Gaps = 2/91 (2%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ +K R E Q+ ++ EE + +++ + RR+E+K E+E+ + E+
Sbjct: 394 EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ-- 451
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
E++ R +E ++ +++K+ +++ KM + + K
Sbjct: 452 EEKIREQEEMMQEQEEKMGEQEGKMCEQEAK 482
Score = 35.8 bits (81), Expect = 0.089
Identities = 20/77 (25%), Positives = 44/77 (57%), Gaps = 2/77 (2%)
Query: 403 KQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEED--PEKQRRLEEAA 460
+++ +K R + E + K ++RQE +EEK R +E++ +E ++++R EE
Sbjct: 312 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 371
Query: 461 LRREQKKLEKKQMKMKQ 477
+R ++K+ E++ +Q
Sbjct: 372 IREQEKRQEQEAKMWRQ 388
Score = 35.4 bits (80), Expect = 0.12
Identities = 18/78 (23%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEA 459
+E K + + +E ++ + E + R +E+KR E+E+I +E +R+ +EA
Sbjct: 328 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE----KRQEQEA 383
Query: 460 ALRREQKKLEKKQMKMKQ 477
+ R+++K+ +++ K+++
Sbjct: 384 KMWRQEEKIREQEEKIRE 401
Score = 35.4 bits (80), Expect = 0.12
Identities = 21/87 (24%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ +K R E Q+ ++ E + +++ + RR+E+K E+E+ + E++
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE- 508
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
EK R EE +E+K E+++ +Q
Sbjct: 509 EKIREQEEMMQEQEEKMWEQEEKMCEQ 535
Score = 35.0 bits (79), Expect = 0.15
Identities = 18/85 (21%), Positives = 49/85 (57%), Gaps = 5/85 (5%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQ---RQEAAQSRREEKKRAEKERIMNEEDPEKQRRL 456
+E ++K + ++ E K+ + R++ + +E+K E+E M E++ + Q
Sbjct: 484 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE-- 541
Query: 457 EEAALRREQKKLEKKQMKMKQIKVK 481
+E +RR+++K+ +++++++Q + K
Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 34.3 bits (77), Expect = 0.26
Identities = 18/85 (21%), Positives = 48/85 (56%), Gaps = 5/85 (5%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQ---RQEAAQSRREEKKRAEKERIMNEEDPEKQRRL 456
+E ++K + ++ E K+ + R++ + +E+K E+E M E++ + Q
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE-- 485
Query: 457 EEAALRREQKKLEKKQMKMKQIKVK 481
+E +RR+++K+ +++ K+++ + K
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEK 510
Score = 33.5 bits (75), Expect = 0.44
Identities = 19/88 (21%), Positives = 46/88 (52%), Gaps = 6/88 (6%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEA 459
+EGK + + + +E ++ + +E + RE++++ ++ M +E EK EE
Sbjct: 472 QEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 531
Query: 460 ALRREQK------KLEKKQMKMKQIKVK 481
+E+K K+ +++ KM++ +V+
Sbjct: 532 MCEQEEKMQEQEEKMRRQEEKMREQEVR 559
Score = 32.3 bits (72), Expect = 0.99
Identities = 20/96 (20%), Positives = 53/96 (55%), Gaps = 12/96 (12%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ +K E Q+ ++ R EE R++ + R +E+K E+E +M E++
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKI-------REQEKKIREQEEKIREQEEMMQEQEE 467
Query: 451 ---EKQRRL--EEAALRREQKKLEKKQMKMKQIKVK 481
E++ ++ +EA ++ +++K+ +++ K+++ + K
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKK 503
Score = 32.0 bits (71), Expect = 1.3
Identities = 19/87 (21%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKE---RIMNEEDP 450
+K + E Q+ ++ EE + + ++ + RR+E+ EKE R + E+
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
E+++ E+ R+E++K+ +++ + +Q
Sbjct: 355 EQEKIREQEEKRQEEEKIREQEKRQEQ 381
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 43.9 bits (102), Expect = 3e-04
Identities = 24/87 (27%), Positives = 51/87 (58%), Gaps = 2/87 (2%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQR--QEAAQSRREEKKRAEKERIMNEE 448
++ K+ R +E + + ++ + EE L+ +R QE + R++KK +KE + E
Sbjct: 917 EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE 976
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKM 475
+PEK+RR E RE+++L++++ ++
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQL 1003
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/95 (28%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKE-------- 442
++ ++ RL RE + + + R E+ + +R+E + RRE++ R E+E
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLR 352
Query: 443 RIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
R EE E+Q R E+ RREQ+ ++Q++ +Q
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Score = 41.6 bits (96), Expect = 0.002
Identities = 20/78 (25%), Positives = 45/78 (57%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEA 459
RE +++ ++ R E+ + +R++ + +EE++R ++ R EE+ +Q+ E
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381
Query: 460 ALRREQKKLEKKQMKMKQ 477
LRREQ+ ++Q++ +Q
Sbjct: 382 QLRREQQLRREQQLRREQ 399
Score = 41.2 bits (95), Expect = 0.002
Identities = 21/88 (23%), Positives = 45/88 (51%)
Query: 390 IDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEED 449
+D+ K+ R + + D+ + + F +E Q RR++++ E+E EE
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 450 PEKQRRLEEAALRREQKKLEKKQMKMKQ 477
EKQ RLE+ +R ++L +++ + ++
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQE 182
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/89 (28%), Positives = 53/89 (59%), Gaps = 5/89 (5%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFL----KLTHVQRQEAAQSRREEKKRAEKERIMN 446
++ +K RL +Q ++ + EE L + T +++ Q R+EE+ + E+E+++
Sbjct: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095
Query: 447 EEDPEKQRRLEEAALRREQKKLEKKQMKM 475
EE PEK+RR E RE+++L++++ ++
Sbjct: 1096 EE-PEKRRRQERERQCREEEELQQEEEQL 1123
Score = 40.8 bits (94), Expect = 0.003
Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 9/87 (10%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKE-----RIMNEEDPEK-- 452
R+ + K D+ R E +LKL +R+E Q RRE++ R E+E R+ +E+ E+
Sbjct: 472 RKQQLKRDQEEER-RERWLKLEEEERREQ-QERREQQLRREQEERREQRLKRQEEEERLQ 529
Query: 453 QRRLEEAALRREQKKLEKKQMKMKQIK 479
QR E LRREQ++ ++ +K ++ K
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEK 556
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/84 (28%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQR--QEAAQSRREEKKRAEKERIMNEEDPE 451
K+ R RE + + ++ + EE L+ +R QE + REE++ ++E + E+PE
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159
Query: 452 KQRRLEEAALRREQKKLEKKQMKM 475
K+RR E RE+++L++++ ++
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQL 1183
Score = 40.0 bits (92), Expect = 0.005
Identities = 19/73 (26%), Positives = 41/73 (56%)
Query: 402 GKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAAL 461
G+++ + R +E + K +Q++E R E +KR +ER + E+ ++ EE L
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL 1124
Query: 462 RREQKKLEKKQMK 474
R E++K +++++
Sbjct: 1125 REEREKRRRQELE 1137
Score = 40.0 bits (92), Expect = 0.005
Identities = 26/87 (29%), Positives = 53/87 (60%), Gaps = 8/87 (9%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQ-RQEAAQSR--REEKKRAEKERIMNEED----PEK 452
R+GK + ++ + ++EE +L + RQ A+ + +EK R E++ + EE+ E+
Sbjct: 1817 RDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER 1876
Query: 453 QRRLEEAALRREQKKLEKKQMKMKQIK 479
+R+L E +RR+QK+ E++ ++ +IK
Sbjct: 1877 ERKLREEHIRRQQKE-EQRHRQVGEIK 1902
Score = 39.7 bits (91), Expect = 0.006
Identities = 20/74 (27%), Positives = 41/74 (55%)
Query: 404 QKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRR 463
++ + R R EE + + Q+ + + EE++ ++ER +E E+Q E LRR
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 464 EQKKLEKKQMKMKQ 477
EQ++ ++Q++ +Q
Sbjct: 342 EQEERREQQLRREQ 355
Score = 39.7 bits (91), Expect = 0.006
Identities = 27/95 (28%), Positives = 53/95 (55%), Gaps = 10/95 (10%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSR--REEKKRAE----KERIMNEEDP 450
RL RE +++ D+ R EE + +++E + R REE +R E +E+ + E+P
Sbjct: 566 RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEP 625
Query: 451 EKQRRLE----EAALRREQKKLEKKQMKMKQIKVK 481
E++RR + E R Q++L ++Q + ++ ++K
Sbjct: 626 EEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Score = 38.9 bits (89), Expect = 0.011
Identities = 24/87 (27%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFL--KLTHVQRQEAAQSRREEKKRAEKERIMNEE 448
++ K+ R RE + + DK + EE L + +RQE + REE++ ++E + E
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKM 475
+ EK+RR E R++ +L++++ ++
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQL 1033
Score = 38.5 bits (88), Expect = 0.014
Identities = 23/88 (26%), Positives = 47/88 (53%), Gaps = 2/88 (2%)
Query: 392 KAKKFRLNREGKQKADKN-RARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
K ++ L RE +++ + R R E+ + +R+E + RRE+++R E++ E+
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339
Query: 451 EK-QRRLEEAALRREQKKLEKKQMKMKQ 477
+ Q E LRREQ++ ++Q ++
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRRE 367
Score = 38.5 bits (88), Expect = 0.014
Identities = 27/98 (27%), Positives = 55/98 (56%), Gaps = 10/98 (10%)
Query: 388 YSIDKAKKFRLNREGKQKADKNRARVEENFLKLTH--VQRQEAAQSRREEKKR--AEKER 443
+ +++ +K R + + A + + R E+ L+ +QR+E + RR+E++R E+E+
Sbjct: 876 WQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQ 935
Query: 444 IMNEEDP------EKQRRLEEAALRREQKKLEKKQMKM 475
+ EE+ EK+RR E R+ KKL++K+ ++
Sbjct: 936 LQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973
Score = 38.1 bits (87), Expect = 0.018
Identities = 20/75 (26%), Positives = 48/75 (64%), Gaps = 4/75 (5%)
Query: 399 NREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLE- 457
+RE +++ + R R +F + ++R+E +++R ++K E+++++ EE EK+RR E
Sbjct: 1278 DREQERRRWQQRDR---HFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
Query: 458 EAALRREQKKLEKKQ 472
+ R E++ L++++
Sbjct: 1335 DRKFREEEQLLQERE 1349
Score = 37.7 bits (86), Expect = 0.023
Identities = 25/92 (27%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 392 KAKKFRLNREGKQKADKNRARV---EENFLKLTHVQRQEAAQSRREEKKRAEKE---RIM 445
+ ++ R+ +E ++K + R V EE L+ QRQ Q E+ ++ E++ R
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290
Query: 446 NEEDPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
EE+ ++QR E LRR+Q++ ++Q + ++
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Score = 37.4 bits (85), Expect = 0.031
Identities = 24/86 (27%), Positives = 50/86 (58%), Gaps = 7/86 (8%)
Query: 398 LNREGKQKADKNRARVEENFLKLTHVQ--RQEAAQSRREEKKRAEKE----RIMNEEDPE 451
L R+G+++ + R ++ + + R+ R+EE+K E+E R + EE+ E
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE-E 276
Query: 452 KQRRLEEAALRREQKKLEKKQMKMKQ 477
+ R+LE LRRE+++ E++Q ++++
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRR 302
Score = 37.4 bits (85), Expect = 0.031
Identities = 20/87 (22%), Positives = 51/87 (58%), Gaps = 1/87 (1%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ ++ +L RE +++ ++ R +E + ++R++ + RRE++ R E++ ++
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQE-EERREQQLRREQQLRREQQLR 390
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
+Q+ E LRREQ+ ++Q++ +Q
Sbjct: 391 REQQLRREQQLRREQQLRREQQLRREQ 417
Score = 37.4 bits (85), Expect = 0.031
Identities = 22/87 (25%), Positives = 50/87 (57%), Gaps = 6/87 (6%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKK----RAEKERIMNEEDPEK 452
+L RE +++ ++ R EE +L +R++ + +EE++ + E+ER E+
Sbjct: 537 QLRREQEERREQLLKREEEK--RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQ 594
Query: 453 QRRLEEAALRREQKKLEKKQMKMKQIK 479
+ RLE+ R E ++LE+++ + +++K
Sbjct: 595 EERLEQRLKREEVERLEQEERREQRLK 621
Score = 37.0 bits (84), Expect = 0.040
Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 7/72 (9%)
Query: 401 EGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAA 460
E ++ D+ + R E L+L R+E Q RRE ++R+ EE+ EK+ R E
Sbjct: 200 ETEEFPDEEQLRRRE-LLELRRKGREEKQQQRRE-----RQDRVFQEEE-EKEWRKRETV 252
Query: 461 LRREQKKLEKKQ 472
LR+E++KL++++
Sbjct: 253 LRKEEEKLQEEE 264
Score = 37.0 bits (84), Expect = 0.040
Identities = 23/82 (28%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRR-EEKKRAEKERIMNEEDPEKQRR 455
RL RE +++ D + E H Q + Q +R +E++R E+ + EE+ +Q+
Sbjct: 446 RLKREQEERRDWLKREEETE----RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE 501
Query: 456 LEEAALRREQKKLEKKQMKMKQ 477
E LRREQ++ ++++K ++
Sbjct: 502 RREQQLRREQEERREQRLKRQE 523
Score = 37.0 bits (84), Expect = 0.040
Identities = 21/87 (24%), Positives = 54/87 (62%), Gaps = 6/87 (6%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ ++ RL RE +++ ++ R E +L +R+E + +REE + +++++ E+
Sbjct: 583 EERRQQRLKREQEERLEQRLKR--EEVERLEQEERRE-QRLKREEPEEERRQQLLKSEEQ 639
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
E++R+ + LRREQ++ ++++K ++
Sbjct: 640 EERRQQQ---LRREQQERREQRLKREE 663
Score = 37.0 bits (84), Expect = 0.040
Identities = 23/90 (25%), Positives = 49/90 (54%), Gaps = 7/90 (7%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ +KFR + Q+ ++ + +E K +E Q RR+E+ R +E+ + ++P
Sbjct: 1458 ERHRKFREEEQLLQEREEQQLHRQERDRKFL----EEEQQLRRQERDRKFREQELRSQEP 1513
Query: 451 EKQRRLEEAALRREQKK---LEKKQMKMKQ 477
E++ EE L R+Q++ L+++Q +Q
Sbjct: 1514 ERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1543
Score = 36.6 bits (83), Expect = 0.052
Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 4/83 (4%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRL 456
+L RE ++K + R +E + + VQ++E R E +KR +E + E+ ++
Sbjct: 1122 QLLREEREK--RRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 457 EEAALRREQKKLEKKQMKMKQIK 479
EE LR EQ+K ++Q + +Q +
Sbjct: 1180 EEQLLREEQEK--RRQERERQYR 1200
Score = 36.6 bits (83), Expect = 0.052
Identities = 24/89 (26%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKR---AEKERIMNE 447
D+ +KFR + Q+ ++ + R +E K R+E Q RR+E++R E++++ +
Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKF----REEEQQLRRQERERKFLQEEQQLRRQ 1719
Query: 448 EDPEKQRRLEEAALRREQKKLEKKQMKMK 476
E K R E+ EQ++L +++ K
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRRQERYRK 1748
Score = 36.2 bits (82), Expect = 0.068
Identities = 22/80 (27%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRL--E 457
RE + K ++ + LK + + Q RRE+++R E+ EE+ ++RL E
Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Query: 458 EAALRREQKKLEKKQMKMKQ 477
RREQ+ E++Q + ++
Sbjct: 676 HEEERREQELAEEEQEQARE 695
Score = 35.8 bits (81), Expect = 0.089
Identities = 23/80 (28%), Positives = 42/80 (52%), Gaps = 6/80 (7%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRL 456
R RE + +A++ + R E+ FL +E + RR +++ EKE EE+ + QRR
Sbjct: 791 REQRERQLRAEERQQR-EQRFLP-----EEEEKEQRRRQRREREKELQFLEEEEQLQRRE 844
Query: 457 EEAALRREQKKLEKKQMKMK 476
L+ E+ L++ Q + +
Sbjct: 845 RAQQLQEEEDGLQEDQERRR 864
Score = 35.8 bits (81), Expect = 0.089
Identities = 21/91 (23%), Positives = 49/91 (53%), Gaps = 6/91 (6%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKR--AEKERIMNEE 448
++ +KFRL + ++ ++ R +E+ ++RQE Q R+E+ R E E+++ E
Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKFMEDE----QQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
+ ++ R E E++ ++Q + +Q++
Sbjct: 1632 EEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Score = 35.8 bits (81), Expect = 0.089
Identities = 25/94 (26%), Positives = 55/94 (58%), Gaps = 10/94 (10%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQR----QEAAQSRREEKKRA-EKERIMNEE 448
+KFR + +Q+ ++ + R +E + K+ ++ +E Q RR+E+ R +E + +E
Sbjct: 1723 RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE 1782
Query: 449 DPEKQRRLEEAALR-REQKKL----EKKQMKMKQ 477
E+Q R +E+ + RE+++L E++Q++ +Q
Sbjct: 1783 REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQ 1816
Score = 35.4 bits (80), Expect = 0.12
Identities = 22/87 (25%), Positives = 51/87 (58%), Gaps = 3/87 (3%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ ++ +L RE +++ + + R E+ + ++R++ Q RRE++ R E++ ++
Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQ--QLRREQQLRREQQLRREQQLR 414
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
+Q+ E LRREQ++ E+ + K +Q
Sbjct: 415 REQQLRREQQLRREQEE-ERHEQKHEQ 440
Score = 35.4 bits (80), Expect = 0.12
Identities = 22/89 (24%), Positives = 50/89 (56%), Gaps = 5/89 (5%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAA---QSRREEKKRAEKERIMNE 447
++ K+ R E + + ++ + EE L+ +R+ Q R EE+ + E+E+++ E
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186
Query: 448 EDPEKQRRLEEAALRREQKKLEKKQMKMK 476
E +++RR E RE+++L++++ K +
Sbjct: 1187 E--QEKRRQERERQYREEEELQRQKRKQR 1213
Score = 35.4 bits (80), Expect = 0.12
Identities = 21/76 (27%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRL 456
+L RE +QK K R R + +L +R+E + + ++K E+E+++ E + + RR
Sbjct: 1298 QLERE-EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356
Query: 457 EEAALRREQKKLEKKQ 472
E RE++ ++Q
Sbjct: 1357 ERDRKFREEELRHQEQ 1372
Score = 35.4 bits (80), Expect = 0.12
Identities = 27/85 (31%), Positives = 48/85 (56%), Gaps = 8/85 (9%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKR--AEKERIMNEEDPEKQR 454
R RE + + D++R EE L +Q E Q RR+E+ R E+E+ + ++ E++
Sbjct: 1654 RQEREQQLRHDRDRKFREEEQL----LQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709
Query: 455 RLEEAALRREQKKLEKKQMKMKQIK 479
EE LRR++ LE+K + +Q++
Sbjct: 1710 LQEEQQLRRQE--LERKFREEEQLR 1732
Score = 35.0 bits (79), Expect = 0.15
Identities = 22/87 (25%), Positives = 49/87 (56%), Gaps = 1/87 (1%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ ++ +L RE +++ + + R E+ + R+E Q RRE++ R E++ ++
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQ-QLRREQQLRREQQLRREQQLR 402
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
+Q+ E LRREQ+ ++Q++ +Q
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQ 429
Score = 35.0 bits (79), Expect = 0.15
Identities = 22/92 (23%), Positives = 48/92 (52%), Gaps = 7/92 (7%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTH------VQRQEAAQSRREEKKRAEKERIM 445
+ ++ R +E ++ K+ E LK ++R+E + +E+++ + +R
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 446 NEEDPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
EE E+ +LEE RREQ++ ++Q++ +Q
Sbjct: 481 EEERRERWLKLEEEE-RREQQERREQQLRREQ 511
Score = 34.7 bits (78), Expect = 0.20
Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 14/103 (13%)
Query: 391 DKAKKFRLNREGKQKAD---------KNRARVEENFLKLTHVQRQEAAQSRREEKKR--A 439
++ KK+R E +Q+ + + R E + K +Q++E R E +KR
Sbjct: 985 EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044
Query: 440 EKERIMNEED---PEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
E+ER EE+ E+++ L E R +++LE++ K ++++
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
Score = 34.7 bits (78), Expect = 0.20
Identities = 22/88 (25%), Positives = 48/88 (54%), Gaps = 6/88 (6%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRA--EKERIMNEE 448
++ ++ R +R+ K + ++ + +E K R+E Q RR+E++R E+E+ + +E
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKF----REEEQQVRRQERERKFLEEEQQLRQE 1458
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKMK 476
K R E+ RE+++L +++ K
Sbjct: 1459 RHRKFREEEQLLQEREEQQLHRQERDRK 1486
Score = 34.3 bits (77), Expect = 0.26
Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 13/89 (14%)
Query: 398 LNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEK-----KRAEKERIMNEEDPEK 452
L RE +++ ++ R E LK +R++ R EE+ KR ++ER+ E+
Sbjct: 550 LKREEEKRLEQER---REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE 606
Query: 453 QRRLE-----EAALRREQKKLEKKQMKMK 476
RLE E L+RE+ + E++Q +K
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLK 635
Score = 34.3 bits (77), Expect = 0.26
Identities = 21/87 (24%), Positives = 48/87 (55%), Gaps = 1/87 (1%)
Query: 395 KFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQR 454
K R N + +Q D ++ R ++ L H+ ++ + R +E++R ++ E+ + +R
Sbjct: 1243 KGRENEQFRQLED-SQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLER 1301
Query: 455 RLEEAALRREQKKLEKKQMKMKQIKVK 481
++ A RR++K E+KQ+ ++ + K
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEK 1328
Score = 34.3 bits (77), Expect = 0.26
Identities = 28/102 (27%), Positives = 56/102 (54%), Gaps = 10/102 (9%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQR---QEAAQSRREEK---KRAEKERI 444
++ +KFR +E + + + + EE L QR QE Q RR+E+ +R +++R
Sbjct: 1498 ERDRKFR-EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK 1556
Query: 445 MNEEDPEKQRRLEEAALRREQK---KLEKKQMKMKQIKVKAM 483
EE+ +Q R E+ R+E+ +LE+++++ ++ + K M
Sbjct: 1557 FREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFM 1598
Score = 33.9 bits (76), Expect = 0.34
Identities = 19/93 (20%), Positives = 50/93 (53%), Gaps = 5/93 (5%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ + F + ++K+++ R R+ ++ Q Q R EE+++ E +R + EE+
Sbjct: 762 EQRRDFTWQWQAEEKSERGRQRLSAR----PPLREQRERQLRAEERQQRE-QRFLPEEEE 816
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM 483
++QRR + +E + LE+++ ++ + + +
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQL 849
Score = 33.1 bits (74), Expect = 0.58
Identities = 21/68 (30%), Positives = 40/68 (58%), Gaps = 4/68 (5%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEA 459
R +Q + + R E+ + ++R++ Q RRE++ R E+E +E+ E++RR E
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQ--QLRREQQLRREQEEERHEQKHEQERR--EQ 445
Query: 460 ALRREQKK 467
L+REQ++
Sbjct: 446 RLKREQEE 453
Score = 33.1 bits (74), Expect = 0.58
Identities = 21/84 (25%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ + R E +++ ++ R EE L+ + ++ + RE+++R E ER EE+
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQ---EEEQLLREEREKRRRQELERQYREEEE 1145
Query: 451 EKQRRLEEAALRREQKKLEKKQMK 474
+Q EE LR E +K +++++
Sbjct: 1146 VQQE--EEQLLREEPEKRRRQELE 1167
Score = 33.1 bits (74), Expect = 0.58
Identities = 17/77 (22%), Positives = 40/77 (51%)
Query: 403 KQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALR 462
+++ +K R + E + +QE Q REE+++ ++ + + E++ + EE L
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL 1154
Query: 463 REQKKLEKKQMKMKQIK 479
RE+ + ++Q +Q +
Sbjct: 1155 REEPEKRRRQELERQYR 1171
Score = 32.7 bits (73), Expect = 0.75
Identities = 20/81 (24%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRL 456
+L RE +++ ++ R EE ++ ++ Q RRE+++R E + + EE+ ++
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLRSEQ--QLRREQEERRE-QLLKREEEKRLEQER 562
Query: 457 EEAALRREQKKLEKKQMKMKQ 477
E L+REQ++ + +K ++
Sbjct: 563 REQRLKREQEERRDQLLKREE 583
Score = 32.7 bits (73), Expect = 0.75
Identities = 25/91 (27%), Positives = 48/91 (52%), Gaps = 16/91 (17%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKR---------AEKERI 444
K+ R RE K + ++ + EE L R+E + RR+E +R E+E++
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLL------REEREKRRRQEWERQYRKKDELQQEEEQL 1033
Query: 445 MNEEDPEKQRRLEEAALRREQKKLEKKQMKM 475
+ EE EK+R E RE+++L++++ ++
Sbjct: 1034 LREE-REKRRLQERERQYREEEELQQEEEQL 1063
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/83 (25%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ--R 454
+L RE + + ++ R E+ + QR + Q R + + E+E +E++ KQ +
Sbjct: 418 QLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK 477
Query: 455 RLEEAALRREQKKLEKKQMKMKQ 477
R +E R KLE+++ + +Q
Sbjct: 478 RDQEEERRERWLKLEEEERREQQ 500
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/90 (23%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Query: 394 KKFRLNREGKQ----KADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEED 449
KK L +E +Q + +K R + E + +QE Q EE++ ++ + +
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 450 PEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
E++ + EE L RE+ + ++Q + +Q +
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCR 1111
Score = 32.0 bits (71), Expect = 1.3
Identities = 19/75 (25%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRL 456
+L RE +K + R +E + + +Q++E R E++KR ++ E+ E QR+
Sbjct: 1152 QLLREEPEK--RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Query: 457 EEAALRREQKKLEKK 471
+ R E ++ + K
Sbjct: 1210 RKQRYRDEDQRSDLK 1224
Score = 32.0 bits (71), Expect = 1.3
Identities = 16/67 (23%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
Query: 410 RARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLE 469
R E FLK + Q+ RE++ R +++R EE+ + R+ + R E++++
Sbjct: 1385 RQERERKFLK----EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR 1440
Query: 470 KKQMKMK 476
+++ + K
Sbjct: 1441 RQERERK 1447
Score = 31.6 bits (70), Expect = 1.7
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 9/91 (9%)
Query: 389 SIDKAKKFRLNREGKQKADKN--RARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMN 446
S ++ + R RE K++ + + R EE L Q +E RR+E+ R +E +
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLL-----QEREEQPLRRQERDRKFREEELR 1368
Query: 447 EEDPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
++ ++ EE LRR+++ E+K +K +Q
Sbjct: 1369 HQEQGRKFLEEEQRLRRQER--ERKFLKEEQ 1397
Score = 31.6 bits (70), Expect = 1.7
Identities = 20/76 (26%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPE 451
+ ++ R R +Q A + ++R EE L QE Q RR+E++R +E + + E
Sbjct: 1838 RQERDRQYRAEEQFATQEKSRREEQELW------QEEEQKRRQERERKLREEHIRRQQKE 1891
Query: 452 KQRRLEEAALRREQKK 467
+QR + ++ ++ K
Sbjct: 1892 EQRHRQVGEIKSQEGK 1907
Score = 30.8 bits (68), Expect = 2.9
Identities = 21/88 (23%), Positives = 49/88 (55%), Gaps = 8/88 (9%)
Query: 401 EGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMN------EE--DPEK 452
EG+++++K + + + ++ + + E++RAE+E++ + EE D E+
Sbjct: 150 EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209
Query: 453 QRRLEEAALRREQKKLEKKQMKMKQIKV 480
RR E LRR+ ++ +++Q + +Q +V
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRV 237
Score = 30.8 bits (68), Expect = 2.9
Identities = 19/77 (24%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ +KFR + +Q+ ++ + R +E+ K + +E + REE++ ++R
Sbjct: 1768 ERDRKFREEEQLRQEREEQQLRSQESDRKF---REEEQLRQEREEQQLRPQQRDGKYRWE 1824
Query: 451 EKQRRLEEAALRREQKK 467
E+Q +LEE R Q++
Sbjct: 1825 EEQLQLEEQEQRLRQER 1841
Score = 30.4 bits (67), Expect = 3.7
Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEK--ERIMNEEDPEKQR 454
+L RE + + ++ R ++ L+ R+E + R E+K E+ +R+ E++ +
Sbjct: 400 QLRREQQLRREQQLRREQQ--LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Query: 455 RLEEAALRREQKKLEKKQMKMKQ 477
E R +++ K+Q+K Q
Sbjct: 458 LKREEETERHEQERRKQQLKRDQ 480
Score = 30.4 bits (67), Expect = 3.7
Identities = 21/91 (23%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
Query: 392 KAKKFRLNRE---GKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEE 448
K KK + E G++ + R E+ + + +Q QE Q REE+++ ++ +
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ-QEEEQLLREEREKRRRQEWERQY 1020
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
+ + + EE L RE+++ + Q + +Q +
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYR 1051
Score = 30.4 bits (67), Expect = 3.7
Identities = 24/96 (25%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
Query: 390 IDKAKKFRLNREGKQKA-DKNRARVEENFLKLTHVQRQEAAQSRR-----EEKK--RAEK 441
+ + ++ R G+Q+ D++R EE L+ ++Q + Q R EE+K R E+
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 442 ERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
ER E++ + +R+ + LR+E+ + ++ ++ Q
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Score = 30.4 bits (67), Expect = 3.7
Identities = 21/98 (21%), Positives = 50/98 (51%), Gaps = 15/98 (15%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEK-----------KRA 439
++ +KFR + ++ ++ R ++E ++RQE + REE+ +R
Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQEE----QQLRRQELERKFREEEQLRQETEQEQLRRQ 1743
Query: 440 EKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
E+ R + EE+ + R E+ R+E+ + +++ +++Q
Sbjct: 1744 ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ 1781
Score = 30.0 bits (66), Expect = 4.9
Identities = 19/88 (21%), Positives = 48/88 (54%), Gaps = 7/88 (7%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKK--RAEKERIMNEE 448
++ +KFR +++ R E FL+ RQE + REE++ + +E+ ++ +
Sbjct: 1427 ERDRKFR-----EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKMK 476
+ +++ EE LRR+++ + ++ +++
Sbjct: 1482 ERDRKFLEEEQQLRRQERDRKFREQELR 1509
Score = 29.6 bits (65), Expect = 6.4
Identities = 23/79 (29%), Positives = 45/79 (56%), Gaps = 8/79 (10%)
Query: 401 EGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAA 460
E ++K + R R E +L ++ +E Q RRE ++ ++E +ED E++R E+
Sbjct: 813 EEEEKEQRRRQRRERE-KELQFLEEEEQLQ-RRERAQQLQEEEDGLQEDQERRRSQEQ-- 868
Query: 461 LRREQK---KLEKKQMKMK 476
RR+QK +LE+++ + +
Sbjct: 869 -RRDQKWRWQLEEERKRRR 886
Score = 29.6 bits (65), Expect = 6.4
Identities = 18/86 (20%), Positives = 46/86 (53%), Gaps = 4/86 (4%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
+KFR + Q+ ++ R +E K R+E + + + +K E+E+ + ++ E++
Sbjct: 1336 RKFREEEQLLQEREEQPLRRQERDRKF----REEELRHQEQGRKFLEEEQRLRRQERERK 1391
Query: 454 RRLEEAALRREQKKLEKKQMKMKQIK 479
EE LR ++++ + +Q + ++ +
Sbjct: 1392 FLKEEQQLRCQEREQQLRQDRDRKFR 1417
Score = 29.6 bits (65), Expect = 6.4
Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 13/78 (16%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKK--RAEKERIMNEEDPEKQRRLE 457
+EG+Q+ + R R + E REE++ R E++R EE+P+ +R+
Sbjct: 1607 QEGQQQLRQERDR---------KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQER 1657
Query: 458 EAALR--REQKKLEKKQM 473
E LR R++K E++Q+
Sbjct: 1658 EQQLRHDRDRKFREEEQL 1675
Score = 29.6 bits (65), Expect = 6.4
Identities = 21/89 (23%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ +KFR + + Q+ ++ + +E K + Q Q R E++ R +++R EE+
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQER-EQQLRHDRDRKFREEEQ 1674
Query: 451 EKQRRLEEAALRREQ--KKLEKKQMKMKQ 477
Q EE LRR++ +K +++ ++++
Sbjct: 1675 LLQEG-EEQQLRRQERDRKFREEEQQLRR 1702
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 16/99 (16%)
Query: 16 SVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQD 75
S SE++ DD EDE+D +D D E +D DS +ED D + E +D
Sbjct: 636 SKSESEEDDEEDEDD----EDEDEEEEDDENGDS----------SEDGGDSS--ESSSED 679
Query: 76 ENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSS 114
E+++GD + D ++ D + + +DE+ E +SSS
Sbjct: 680 ESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718
Score = 37.4 bits (85), Expect = 0.031
Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 2/48 (4%)
Query: 71 LEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKD 118
L+ + E++E D ED D ++ D E E DDE + ED D+S S ++D
Sbjct: 634 LQSKSESEEDDEEDEDDEDEDEEEE--DDENGDSSEDGGDSSESSSED 679
Score = 37.0 bits (84), Expect = 0.040
Identities = 18/58 (31%), Positives = 29/58 (50%)
Query: 61 EDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKD 118
ED++DE E E DEN + + D+ E +E E D +E E ++ D ++D
Sbjct: 646 EDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDED 703
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 16/99 (16%)
Query: 16 SVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQD 75
S SE++ DD EDE+D +D D E +D DS +ED D + E +D
Sbjct: 636 SKSESEEDDEEDEDD----EDEDEEEEDDENGDS----------SEDGGDSS--ESSSED 679
Query: 76 ENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSS 114
E+++GD + D ++ D + + +DE+ E +SSS
Sbjct: 680 ESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718
Score = 37.4 bits (85), Expect = 0.031
Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 2/48 (4%)
Query: 71 LEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKD 118
L+ + E++E D ED D ++ D E E DDE + ED D+S S ++D
Sbjct: 634 LQSKSESEEDDEEDEDDEDEDEEEE--DDENGDSSEDGGDSSESSSED 679
Score = 37.0 bits (84), Expect = 0.040
Identities = 18/58 (31%), Positives = 29/58 (50%)
Query: 61 EDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKD 118
ED++DE E E DEN + + D+ E +E E D +E E ++ D ++D
Sbjct: 646 EDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDED 703
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 16/99 (16%)
Query: 16 SVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQD 75
S SE++ DD EDE+D +D D E +D DS +ED D + E +D
Sbjct: 673 SKSESEEDDEEDEDD----EDEDEEEEDDENGDS----------SEDGGDSS--ESSSED 716
Query: 76 ENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSS 114
E+++GD + D ++ D + + +DE+ E +SSS
Sbjct: 717 ESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 755
Score = 37.4 bits (85), Expect = 0.031
Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 2/48 (4%)
Query: 71 LEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKD 118
L+ + E++E D ED D ++ D E E DDE + ED D+S S ++D
Sbjct: 671 LQSKSESEEDDEEDEDDEDEDEEEE--DDENGDSSEDGGDSSESSSED 716
Score = 37.0 bits (84), Expect = 0.040
Identities = 18/58 (31%), Positives = 29/58 (50%)
Query: 61 EDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKD 118
ED++DE E E DEN + + D+ E +E E D +E E ++ D ++D
Sbjct: 683 EDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDED 740
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 43.9 bits (102), Expect = 3e-04
Identities = 28/89 (31%), Positives = 52/89 (58%), Gaps = 3/89 (3%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
KK +L R+ Q+ ++ R E+ + +RQ A + +++E + E+ER E+ +++
Sbjct: 269 KKRQLERQKLQELEQQRE--EQKRREKEAEERQRAEERKQKELEELERERKREEKLRKRE 326
Query: 454 RRLEEAALRREQKKLEKKQM-KMKQIKVK 481
++ + LRR QKKLEK Q + KQ++ K
Sbjct: 327 QKQRDRELRRNQKKLEKLQAEEQKQLQEK 355
Score = 37.7 bits (86), Expect = 0.023
Identities = 21/69 (30%), Positives = 42/69 (60%), Gaps = 5/69 (7%)
Query: 419 KLTHVQRQEAAQSRRE----EKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMK 474
KL +++Q Q RRE E++RAE+ + E+ E++R+ EE LR+ ++K ++++
Sbjct: 277 KLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEK-LRKREQKQRDRELR 335
Query: 475 MKQIKVKAM 483
Q K++ +
Sbjct: 336 RNQKKLEKL 344
Score = 33.5 bits (75), Expect = 0.44
Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 17/104 (16%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEA-----------AQSRREEKKRAEKE 442
KK + +QK + + ++EE L L Q A RE++++ EK
Sbjct: 339 KKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKL 398
Query: 443 RIMNEEDPEKQRRLEEAALRREQKKLEKK---QMKMKQIKVKAM 483
R+ +E+ +RRL+EA LRR +++ E+ Q K ++++ + +
Sbjct: 399 RLQQQEE---RRRLQEAELRRVEEEKERALGLQRKERELRERLL 439
Score = 33.1 bits (74), Expect = 0.58
Identities = 23/97 (23%), Positives = 56/97 (57%), Gaps = 4/97 (4%)
Query: 390 IDKAKKFRLNREGKQKADKNRARVEENFLK-LTHVQRQEAAQS--RREEKKRAEKERIMN 446
+ + ++ R ++ ++K + R R EE K L ++R+ + R+ E+K+ ++E N
Sbjct: 278 LQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRN 337
Query: 447 EEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM 483
++ EK + E+ L +E+ KLE++++ + Q ++++
Sbjct: 338 QKKLEKLQAEEQKQL-QEKIKLEERKLLLAQRNLQSI 373
Score = 30.8 bits (68), Expect = 2.9
Identities = 24/100 (24%), Positives = 47/100 (47%), Gaps = 3/100 (3%)
Query: 376 MEALLPLMNM-VIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRRE 434
++A+ L M ++Y + K N + + K+ + +L + QE Q R E
Sbjct: 228 IQAMSALRGMKLMYKGEDGKAVACNIKVSFDSTKHLSDASIKKRQLERQKLQELEQQREE 287
Query: 435 EKKRAEKERIMNEEDPEKQRRLEEAAL--RREQKKLEKKQ 472
+K+R ++ + KQ+ LEE +RE+K +++Q
Sbjct: 288 QKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQ 327
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 43.1 bits (100), Expect = 6e-04
Identities = 28/89 (31%), Positives = 48/89 (53%), Gaps = 7/89 (7%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNE------EDPEKQ 453
+EGK + + + R +E L+ + +E + RE+KK E+E M E E EK
Sbjct: 267 QEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKM 326
Query: 454 RRLEEAALRREQKKLE-KKQMKMKQIKVK 481
R EE R+E++ E +KQM+ ++ K++
Sbjct: 327 REQEEKMWRQEERLWEQEKQMREQEQKMR 355
Score = 38.1 bits (87), Expect = 0.018
Identities = 20/82 (24%), Positives = 48/82 (58%), Gaps = 4/82 (4%)
Query: 404 QKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPE----KQRRLEEA 459
+K ++ R EE + R++ + RR+EK+ E+E+ + E++ E K+ R +E
Sbjct: 251 RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEE 310
Query: 460 ALRREQKKLEKKQMKMKQIKVK 481
++ +++K+ +++ KM++ + K
Sbjct: 311 QMQEQEEKMWEQEEKMREQEEK 332
Score = 37.7 bits (86), Expect = 0.023
Identities = 21/89 (23%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEE----DPEK 452
R+ + ++ +K E+ + + +E +++ +EKK ++E M EE + EK
Sbjct: 508 RMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK 567
Query: 453 QRRLEEAALRREQKKLEKKQMKMKQIKVK 481
+ R EE +R +++K+++++ KM++ + K
Sbjct: 568 KMREEEEMMREQEEKMQEQEEKMREQEEK 596
Score = 37.4 bits (85), Expect = 0.031
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 9/80 (11%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEE----DPEKQRR 455
RE +QK R+ E +L +E + RE++K E+E M EE + EK+ R
Sbjct: 348 REQEQKMRDQEERMWEQDERL-----REKEERMREQEKMWEQEEKMQEEERIREREKKMR 402
Query: 456 LEEAALRREQKKLEKKQMKM 475
EE +R +++K++K++ M
Sbjct: 403 EEEETMREQEEKMQKQEENM 422
Score = 36.2 bits (82), Expect = 0.068
Identities = 22/91 (24%), Positives = 46/91 (50%), Gaps = 7/91 (7%)
Query: 391 DKAKKFR----LNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMN 446
++ KK R + RE ++K + ++ E K+ QE +EEK ++E++
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE---QEEKMQEQEEKMWEQEEKMWE 620
Query: 447 EEDPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
+E+ +K + EE +E+K E+++ +Q
Sbjct: 621 QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ 651
Score = 35.8 bits (81), Expect = 0.089
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP- 450
+ +K +E K + +K E+ R+E RE+K R E+E + +E+
Sbjct: 524 REQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 583
Query: 451 ----EKQRRLEEAALRREQKKLEKKQMKMKQ 477
EK R EE +E+K E+++ +Q
Sbjct: 584 QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 614
Score = 35.4 bits (80), Expect = 0.12
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPE 451
+ +K +E K + + R EE + R+E R +E+K E+E M E++ E
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-E 595
Query: 452 KQRRLEEAALRREQKKLEKKQMKMKQ 477
K EE +E+K E+++ +Q
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQ 621
Score = 33.9 bits (76), Expect = 0.34
Identities = 17/57 (29%), Positives = 38/57 (66%), Gaps = 3/57 (5%)
Query: 423 VQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIK 479
+++QE R+EE+ R ++ ++ +E EK RR +E LR ++K+L +++ ++++ K
Sbjct: 250 IRKQEEKMWRQEERLREQEGKMREQE--EKMRR-QEKRLREQEKELREQEKELREQK 303
Score = 33.9 bits (76), Expect = 0.34
Identities = 20/84 (23%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRL 456
R+ + ++ +K E+ + + QE + R EKK E+E M E++ EK ++
Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE-EKMQKQ 418
Query: 457 EEAALRREQKKLEKKQMKMKQIKV 480
EE +E+K+ +++++ ++ K+
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKEKL 442
Score = 33.5 bits (75), Expect = 0.44
Identities = 20/79 (25%), Positives = 45/79 (56%), Gaps = 6/79 (7%)
Query: 403 KQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP-----EKQRRLE 457
+++ DK + + E + + +Q QE +EEK R ++E++ +E+ EK R E
Sbjct: 621 QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
Query: 458 EAALRREQKKLEKKQMKMK 476
E ++ +++K+ +++ KM+
Sbjct: 681 E-KMQGQEEKMREQEEKMR 698
Score = 32.7 bits (73), Expect = 0.75
Identities = 23/88 (26%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP--- 450
KK R E Q+ ++ EE + ++ + +EK+ E+E+ M +++
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 362
Query: 451 EKQRRLEEAALR-REQKKLEKKQMKMKQ 477
E+ RL E R REQ+K+ +++ KM++
Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQE 390
Score = 32.7 bits (73), Expect = 0.75
Identities = 20/87 (22%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIM---NEE 448
+ K+ R+ + K + + + EE + R+E R +E+K ++E M E+
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 428
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKM 475
+ ++QR E+ EQ+K+++++ K+
Sbjct: 429 EWQQQRLPEQKEKLWEQEKMQEQEEKI 455
Score = 32.7 bits (73), Expect = 0.75
Identities = 21/78 (26%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEA 459
RE ++K + +++E K+ +++E + EE K E+E +M E++ EK + EE
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMW--EQEEKMWEQEEEDKMQEQEEMMWEQE-EKMQEQEEK 647
Query: 460 ALRREQKKLEKKQMKMKQ 477
+E+K E+++ +Q
Sbjct: 648 MWEQEEKMREQEEKMREQ 665
Score = 32.3 bits (72), Expect = 0.99
Identities = 19/93 (20%), Positives = 47/93 (50%), Gaps = 8/93 (8%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRRE--------EKKRAEKERIMNEE 448
++ E + + + + R EE ++ + QE + RE E+K E+E M E+
Sbjct: 555 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 614
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
+ + + EE ++ +++ + +++ KM++ + K
Sbjct: 615 EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/84 (23%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPE 451
+ K+ R+ + K + + R E+ + + + R EE+ R E+E+ M EE E
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR-EREKKMREE--E 573
Query: 452 KQRRLEEAALRREQKKLEKKQMKM 475
+ R +E ++ +++K+ +++ KM
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKM 597
Score = 32.0 bits (71), Expect = 1.3
Identities = 19/85 (22%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 399 NREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEE 458
++E K + ++ E+ + + R++ + + +E+K E+E M E++ EK + EE
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE-EKMQEQEE 609
Query: 459 AALRREQKKLEKKQMKMKQIKVKAM 483
+E+K E+++ Q + + M
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMM 634
Score = 30.8 bits (68), Expect = 2.9
Identities = 19/91 (20%), Positives = 47/91 (51%), Gaps = 4/91 (4%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEE-- 448
++ K+ R + ++ K R + E+ + + QE +EEK ++ER+ +E
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 449 --DPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
+ E++ R +E + + ++L +K+ +M++
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMRE 377
Score = 30.8 bits (68), Expect = 2.9
Identities = 16/76 (21%), Positives = 44/76 (57%), Gaps = 4/76 (5%)
Query: 404 QKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEED----PEKQRRLEEA 459
++ +K + + E+ + + ++ QE +EEK + ++E++ +E+ E++ R +E
Sbjct: 636 EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695
Query: 460 ALRREQKKLEKKQMKM 475
+R +++K+ ++ KM
Sbjct: 696 KMRGQEEKMWGQEEKM 711
Score = 30.0 bits (66), Expect = 4.9
Identities = 24/87 (27%), Positives = 51/87 (58%), Gaps = 6/87 (6%)
Query: 396 FRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEK-ERIMNEEDPEKQR 454
+R E +++ K R + E+ + + ++ QE RE++++ + E+ + E+ EK+
Sbjct: 237 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM--REQEEKMRRQEKRLREQ--EKEL 292
Query: 455 RLEEAALRREQKKLEKKQMKMKQIKVK 481
R +E L REQKKL +++ +M++ + K
Sbjct: 293 REQEKEL-REQKKLREQEEQMQEQEEK 318
Score = 30.0 bits (66), Expect = 4.9
Identities = 19/59 (32%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
Query: 425 RQEAAQSRREEKKRAEKERIMNEEDP---EKQRRLEEAALR-REQKKLEKKQMKMKQIK 479
R++ Q +E+K ++E+ M +++ E+ RL E R REQKK+ +++ KM++ K
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
Score = 29.6 bits (65), Expect = 6.4
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 9/84 (10%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEA 459
+E K + + + R +E +Q QE +EEK + ++E++ +E EK R EE
Sbjct: 651 QEEKMREQEEKMREQEE-----KMQGQEEKMREQEEKMQGQEEKMREQE--EKMRGQEEK 703
Query: 460 ALRREQKK--LEKKQMKMKQIKVK 481
+E+K E+K ++++ K
Sbjct: 704 MWGQEEKMWGQEEKMWGQEEMREK 727
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 43.1 bits (100), Expect = 6e-04
Identities = 22/88 (25%), Positives = 52/88 (59%), Gaps = 3/88 (3%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP---EKQ 453
+++ + K + + + + EE + Q QEA R+EEK R ++E+I +E+ +++
Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEE 505
Query: 454 RRLEEAALRREQKKLEKKQMKMKQIKVK 481
+ E+ +R E+K+ E+++M ++ K++
Sbjct: 506 KIHEQEKIREEEKRQEQEEMWRQEEKIR 533
Score = 42.7 bits (99), Expect = 7e-04
Identities = 28/90 (31%), Positives = 54/90 (60%), Gaps = 4/90 (4%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEE--- 448
+A+ L +E + + K +A+VEEN L Q+QE R+EEK + +E+I +E
Sbjct: 325 QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 384
Query: 449 -DPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
+ E++ R +E +RR+++ + +K+ KM++
Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEKEEKMRR 414
Score = 39.3 bits (90), Expect = 0.008
Identities = 26/96 (27%), Positives = 54/96 (56%), Gaps = 14/96 (14%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEED-----PE 451
RLN++ ++K + +++E K +Q QE +EEK R ++E++ +E+ E
Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEK---IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 410
Query: 452 KQRRLE------EAALRREQKKLEKKQMKMKQIKVK 481
K RR E E +RR+++ + +K+ K+++++ K
Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 446
Score = 38.9 bits (89), Expect = 0.011
Identities = 22/87 (25%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ +K R E Q+ ++ EE + +++ + RR+E+K E+E+ + E++
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE- 654
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
EK R EE +E+K E+++ +Q
Sbjct: 655 EKIREQEEMMQEQEEKMWEQEEKMCEQ 681
Score = 38.5 bits (88), Expect = 0.014
Identities = 21/89 (23%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Query: 397 RLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEE----DPEK 452
++ E K++ + R EE + + RQ+ +EEK R ++E++ +E D E+
Sbjct: 512 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEE 571
Query: 453 QRRLEEAALRREQKKLEKKQMKMKQIKVK 481
+ R +E + R+++K+ +++ K+++ + K
Sbjct: 572 KIREQEEKVWRQEEKIREQEEKIREQEEK 600
Score = 37.7 bits (86), Expect = 0.023
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 8/86 (9%)
Query: 400 REGKQKADKNRARVEENFLKLTH----VQRQEAAQSRREEKKRAEKERIMNEEDPEKQRR 455
+E ++K + ++ E K+ ++RQE +EEK R ++E + +E EK RR
Sbjct: 371 QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE--EKMRR 428
Query: 456 LEEAALRREQK--KLEKKQMKMKQIK 479
EE +E+K +LE+K + ++I+
Sbjct: 429 QEEMMWEKEEKIRELEEKMHEQEKIR 454
Score = 37.7 bits (86), Expect = 0.023
Identities = 20/91 (21%), Positives = 49/91 (53%), Gaps = 2/91 (2%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
D+ +K R E + ++ EE + R++ ++ +E+K E+E M E++
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
+ Q +E +RR+++K+ +++ K+++ + K
Sbjct: 628 KMQE--QEEKMRRQEEKIREQEKKIREQEEK 656
Score = 37.7 bits (86), Expect = 0.023
Identities = 23/84 (27%), Positives = 48/84 (57%), Gaps = 3/84 (3%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
K +R + +++ +K R + E+ + Q QE +EEK ++E++ +E EK
Sbjct: 579 KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE--EKM 636
Query: 454 RRLEEAALRREQKKLEKKQMKMKQ 477
RR EE +R ++KK+ +++ K+++
Sbjct: 637 RRQEE-KIREQEKKIREQEEKIRE 659
Score = 36.6 bits (83), Expect = 0.052
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 4/92 (4%)
Query: 391 DKAKKFRLNREG-KQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEED 449
++ +K R E +++ +K R + E + K ++RQE +EEK R ++E + +E
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE- 437
Query: 450 PEKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
EK R LEE + ++K E+++ + ++ K++
Sbjct: 438 -EKIRELEE-KMHEQEKIREQEEKRQEEEKIR 467
Score = 36.6 bits (83), Expect = 0.052
Identities = 21/76 (27%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 404 QKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEED--PEKQRRLEEAAL 461
+K +K R + E + K ++RQE +EEK R +E++ +E ++++R EE +
Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 466
Query: 462 RREQKKLEKKQMKMKQ 477
R ++K+ E++ +Q
Sbjct: 467 REQEKRQEQEAKMWRQ 482
Score = 36.2 bits (82), Expect = 0.068
Identities = 24/97 (24%), Positives = 52/97 (53%), Gaps = 10/97 (10%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQ------EAAQSRREEKKRAEKERI 444
+K +K R E + ++ R EE + R+ E + R +E+KR E+E+I
Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 466
Query: 445 MNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
+E +R+ +EA + R+++K+ +++ K+++ + K
Sbjct: 467 REQE----KRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Score = 35.8 bits (81), Expect = 0.089
Identities = 22/88 (25%), Positives = 46/88 (52%), Gaps = 7/88 (7%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ +K R E ++ +K EE + + +++ + +E+K E+E M E++
Sbjct: 631 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE- 689
Query: 451 EKQRRLE------EAALRREQKKLEKKQ 472
EK RR E E LR++++K+++ Q
Sbjct: 690 EKMRRQEEKMWEQEVRLRQQEEKMQEHQ 717
Score = 34.7 bits (78), Expect = 0.20
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 5/83 (6%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNE-----EDPEKQR 454
RE ++K + ++ E +RQE + R+E+K E+E I + E EK R
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553
Query: 455 RLEEAALRREQKKLEKKQMKMKQ 477
+ EE R+E+K ++++ +Q
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQ 576
Score = 34.7 bits (78), Expect = 0.20
Identities = 24/84 (28%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
+K R E ++ +K + E+ + + RQE +EEK R ++E++ +E EK
Sbjct: 530 EKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQE--EKI 587
Query: 454 RRLEEAALRREQKKLEKKQMKMKQ 477
R EE +E+K E+++M +Q
Sbjct: 588 REQEEKIREQEEKIREQEEMTQEQ 611
Score = 34.3 bits (77), Expect = 0.26
Identities = 22/84 (26%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
K +R + + +K R + E+ + + ++ QE +EEK R ++E M +E EK
Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE--MTQEQEEKM 615
Query: 454 RRLEEAALRREQKKLEKKQMKMKQ 477
EE +E+K E+++ +Q
Sbjct: 616 GEQEEKMCEQEEKMQEQEEKMRRQ 639
Score = 33.9 bits (76), Expect = 0.34
Identities = 18/85 (21%), Positives = 49/85 (57%), Gaps = 5/85 (5%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQ---RQEAAQSRREEKKRAEKERIMNEEDPEKQRRL 456
+E ++K + ++ E K+ + R++ + +E+K E+E M E++ + Q
Sbjct: 630 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE-- 687
Query: 457 EEAALRREQKKLEKKQMKMKQIKVK 481
+E +RR+++K+ +++++++Q + K
Sbjct: 688 QEEKMRRQEEKMWEQEVRLRQQEEK 712
Score = 33.1 bits (74), Expect = 0.58
Identities = 19/90 (21%), Positives = 48/90 (53%), Gaps = 3/90 (3%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKE---RIMNE 447
++ +K R E ++ ++ EE + + ++ + RR+E+ EKE R + E
Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445
Query: 448 EDPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
+ E+++ E+ R+E++K+ +++ + +Q
Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQ 475
Score = 33.1 bits (74), Expect = 0.58
Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 8/87 (9%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ +K E Q+ ++ R EE R++ + R +E+K E+E +M E++
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKI-------REQEKKIREQEEKIREQEEMMQEQE- 668
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQ 477
EK EE +E+K E+++ +Q
Sbjct: 669 EKMWEQEEKMCEQEEKMQEQEEKMRRQ 695
Score = 30.8 bits (68), Expect = 2.9
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
+K E +K ++ R EE R++ + R+E+K E+E + E++ EK
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE-EKI 601
Query: 454 RRLEEAALRREQKKLEKKQMKMKQ 477
R EE +E+K E+++ +Q
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCEQ 625
Score = 30.4 bits (67), Expect = 3.7
Identities = 22/91 (24%), Positives = 49/91 (53%), Gaps = 7/91 (7%)
Query: 394 KKFRLNREGKQKADKNRARV--EENFLKLTH----VQRQEAAQSRREEKKRAEKERIMNE 447
+K R E +Q+ +K R + +E K+ ++ QE +EEK ++E+I +
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ 510
Query: 448 ED-PEKQRRLEEAALRREQKKLEKKQMKMKQ 477
E E+++R E+ + R+++K+ +++ +Q
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541
Score = 30.4 bits (67), Expect = 3.7
Identities = 19/91 (20%), Positives = 53/91 (58%), Gaps = 7/91 (7%)
Query: 392 KAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAA--QSRREEKKR--AEKERIMNE 447
+AK +R + +++ +K R + E+ + + + QE + +R+E++ ++E+I +
Sbjct: 476 EAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 535
Query: 448 EDPEKQRRL---EEAALRREQKKLEKKQMKM 475
E+ +Q+ +E +R++++K+ +++ KM
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKM 566
Score = 30.0 bits (66), Expect = 4.9
Identities = 22/91 (24%), Positives = 48/91 (52%), Gaps = 10/91 (10%)
Query: 400 REGKQKADKNRARVEENFLKLTH-VQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRL-- 456
+E +Q+ + R EE + ++ QE R+EEK E+E+I EE ++Q +
Sbjct: 469 QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH-EQEKIREEEKRQEQEEMWR 527
Query: 457 ------EEAALRREQKKLEKKQMKMKQIKVK 481
E+ + R+++K+ +++ K+++ + K
Sbjct: 528 QEEKIREQEEIWRQKEKIHEQEEKIRKQEEK 558
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 43.1 bits (100), Expect = 6e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 18 SEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELE----G 73
S+A+ D ++EE+ E +D + + ED E+ E E DED+ V E G
Sbjct: 158 SDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFG 217
Query: 74 QDENQEGDFEDADTQEGDTESEPYDDEEFEGYED 107
DE E + ED + +EG + + + EG +D
Sbjct: 218 LDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251
Score = 38.1 bits (87), Expect = 0.018
Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 8/59 (13%)
Query: 59 ITEDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNK 117
+ E++EDE EG+DE E D ED + +E D E + +DE+ EG ED + S + +
Sbjct: 165 VDEEEEDE-----EGEDEEDEDD-EDGEEEEFDEEDD--EDEDVEGDEDDDEVSEEEEE 215
Score = 38.1 bits (87), Expect = 0.018
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 5/81 (6%)
Query: 15 GSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQ 74
G E + D+ +EE+ E DD D D +D V+E + + E+DEDE +
Sbjct: 174 GEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDE-----DED 228
Query: 75 DENQEGDFEDADTQEGDTESE 95
+E +EG + +E D E E
Sbjct: 229 EEEEEGGKGEKRKRETDDEGE 249
Score = 37.0 bits (84), Expect = 0.040
Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 8/97 (8%)
Query: 23 DDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDF 82
+D E + E D D E ++ ED E ED E+E E + +DE+ EGD
Sbjct: 151 EDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDD------EDGEEEEFDEEDDEDEDVEGDE 204
Query: 83 EDADTQEGDTE--SEPYDDEEFEGYEDKPDTSSSKNK 117
+D + E + E + D++E E E++ K K
Sbjct: 205 DDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRK 241
Score = 36.6 bits (83), Expect = 0.052
Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 10/106 (9%)
Query: 13 VFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELE 72
VF + + + D D ED E D+D AE + V E+ E ED+EDE + E
Sbjct: 135 VFKLLPQLTYLDGYDRED-QEAPDSD-AEVDGVDEEEEDEEG------EDEEDEDDEDGE 186
Query: 73 GQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKD 118
++E E D ED D EGD + + +EE E D+ D ++++
Sbjct: 187 -EEEFDEEDDEDEDV-EGDEDDDEVSEEEEEFGLDEEDEDEDEDEE 230
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 43.1 bits (100), Expect = 6e-04
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 4/74 (5%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
KK RL + ++K DK R + +E +K +E+ + EEKK+ ++E +E+ K+
Sbjct: 56 KKKRLEDDKRKKEDKERKKKDEEKVKA----EEESKKKEEEEKKKHQEEERKKQEEQAKR 111
Query: 454 RRLEEAALRREQKK 467
++ EEAA + ++K+
Sbjct: 112 QQEEEAAAQMKEKE 125
Score = 37.4 bits (85), Expect = 0.031
Identities = 23/87 (26%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 395 KFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQR 454
K +E + + + R+E++ K +R++ + EEK +AE+E EE+ +K+
Sbjct: 42 KLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKK----KDEEKVKAEEESKKKEEEEKKKH 97
Query: 455 RLEEAALRREQKKLEKKQMKMKQIKVK 481
+ EE + EQ K ++++ Q+K K
Sbjct: 98 QEEERKKQEEQAKRQQEEEAAAQMKEK 124
Score = 32.3 bits (72), Expect = 0.99
Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
Query: 47 EDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYE 106
+DS+TE + ED+E+E E + E Q G+ + + E + S+ DDE E E
Sbjct: 1020 KDSMTEGEN---LEEDEEEE---EGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE 1073
Query: 107 DKPDTSSSKNKD 118
+ D + NK+
Sbjct: 1074 ENTDYLTDSNKE 1085
Score = 31.2 bits (69), Expect = 2.2
Identities = 20/97 (20%), Positives = 51/97 (52%), Gaps = 8/97 (8%)
Query: 58 IITEDDEDETTVELEGQDENQEGDFEDADTQE---GDTE-SEPYDDEEFEGYEDKPDTSS 113
++ + D ++ E E +E++E + A+T+E ++E +EP ++E + +D+ +
Sbjct: 1013 LVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEE 1072
Query: 114 SKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYI 150
+N D +T ++ +N + E+++ G L ++
Sbjct: 1073 EENTDYLT----DSNKENETDEENTEVMIKGGGLKHV 1105
Score = 30.8 bits (68), Expect = 2.9
Identities = 20/85 (23%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
Query: 393 AKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEK 452
+ K R + K A K ++ E+ K ++ + + +E KK+ ++E++ EE+ +K
Sbjct: 32 SSKERPKDDIKLTAKKEVSKAPED--KKKRLEDDKRKKEDKERKKK-DEEKVKAEEESKK 88
Query: 453 QRRLEEAALRREQKKLEKKQMKMKQ 477
+ E+ + E++K +++Q K +Q
Sbjct: 89 KEEEEKKKHQEEERKKQEEQAKRQQ 113
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 43.1 bits (100), Expect = 6e-04
Identities = 23/74 (31%), Positives = 44/74 (59%), Gaps = 4/74 (5%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
KK RL + ++K DK R + +E +K +E+ + EEKK+ ++E +E+ K+
Sbjct: 56 KKKRLEDDKRKKEDKERKKKDEEKVKA----EEESKKKEEEEKKKHQEEERKKQEEQAKR 111
Query: 454 RRLEEAALRREQKK 467
++ EEAA + ++K+
Sbjct: 112 QQEEEAAAQMKEKE 125
Score = 37.4 bits (85), Expect = 0.031
Identities = 23/87 (26%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Query: 395 KFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQR 454
K +E + + + R+E++ K +R++ + EEK +AE+E EE+ +K+
Sbjct: 42 KLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKK----KDEEKVKAEEESKKKEEEEKKKH 97
Query: 455 RLEEAALRREQKKLEKKQMKMKQIKVK 481
+ EE + EQ K ++++ Q+K K
Sbjct: 98 QEEERKKQEEQAKRQQEEEAAAQMKEK 124
Score = 32.3 bits (72), Expect = 0.99
Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
Query: 47 EDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYE 106
+DS+TE + ED+E+E E + E Q G+ + + E + S+ DDE E E
Sbjct: 1020 KDSMTEGEN---LEEDEEEE---EGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEE 1073
Query: 107 DKPDTSSSKNKD 118
+ D + NK+
Sbjct: 1074 ENTDYLTDSNKE 1085
Score = 31.2 bits (69), Expect = 2.2
Identities = 20/97 (20%), Positives = 51/97 (52%), Gaps = 8/97 (8%)
Query: 58 IITEDDEDETTVELEGQDENQEGDFEDADTQE---GDTE-SEPYDDEEFEGYEDKPDTSS 113
++ + D ++ E E +E++E + A+T+E ++E +EP ++E + +D+ +
Sbjct: 1013 LVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEE 1072
Query: 114 SKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYI 150
+N D +T ++ +N + E+++ G L ++
Sbjct: 1073 EENTDYLT----DSNKENETDEENTEVMIKGGGLKHV 1105
Score = 30.8 bits (68), Expect = 2.9
Identities = 20/85 (23%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
Query: 393 AKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEK 452
+ K R + K A K ++ E+ K ++ + + +E KK+ ++E++ EE+ +K
Sbjct: 32 SSKERPKDDIKLTAKKEVSKAPED--KKKRLEDDKRKKEDKERKKK-DEEKVKAEEESKK 88
Query: 453 QRRLEEAALRREQKKLEKKQMKMKQ 477
+ E+ + E++K +++Q K +Q
Sbjct: 89 KEEEEKKKHQEEERKKQEEQAKRQQ 113
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 43.1 bits (100), Expect = 6e-04
Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 393 AKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP-- 450
A++ R +++ ++ R E + +RQ A Q RR E++R + ER + E +
Sbjct: 685 AEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKAL 744
Query: 451 -----EKQRRLEEAALRREQKKLEKKQMKMKQIK 479
+ QR LEE + EQ++L ++Q++ +Q K
Sbjct: 745 RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 778
Score = 37.7 bits (86), Expect = 0.023
Identities = 23/84 (27%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Query: 398 LNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLE 457
+ R + D + VE+ +L +++R+E A+ R +K +K R + E +++ RL
Sbjct: 520 IKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR 579
Query: 458 EAALRREQKKLEKKQMKMKQIKVK 481
+ RE+ + + K+ K KQI+ K
Sbjct: 580 KVLQARERVE-QMKEEKKKQIEQK 602
Score = 37.7 bits (86), Expect = 0.023
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 391 DKAKKFRLNREGKQK--ADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEE 448
+KAK+ RL E +K A K VE + +R Q EE++ E + EE
Sbjct: 611 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 670
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
+ E+ R+ EA EQ++ E+++ + ++
Sbjct: 671 EQERLRKAAEAKRLAEQREQERREQERRE 699
Score = 34.3 bits (77), Expect = 0.26
Identities = 26/101 (25%), Positives = 54/101 (53%), Gaps = 15/101 (14%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSR---REEKKRAEKERIMNE 447
+K +K + R ++KA K A + ++ Q +EA + R +EE++R +E + +
Sbjct: 608 EKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKK 667
Query: 448 EDPEKQRRLEEAAL-----------RREQKKLEKKQMKMKQ 477
++ E+Q RL +AA RREQ++ E+++ + ++
Sbjct: 668 KE-EEQERLRKAAEAKRLAEQREQERREQERREQERREQER 707
Score = 33.1 bits (74), Expect = 0.58
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 9/81 (11%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKR-----AEKERIMNE----EDP 450
R +++ ++ R E + + QE Q+ RE ++R +KE++ E +
Sbjct: 702 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 761
Query: 451 EKQRRLEEAALRREQKKLEKK 471
E+Q+RL E L+ EQ+K K+
Sbjct: 762 EEQQRLAERQLQEEQEKKAKE 782
Score = 32.7 bits (73), Expect = 0.75
Identities = 17/91 (18%), Positives = 50/91 (54%), Gaps = 4/91 (4%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ ++ ++ + +++ ++ + + EE K+ +Q +E + +EEKK+ +++ +
Sbjct: 552 EQLRRQKVEEDKRRRLEEVKLKREERLRKV--LQARERVEQMKEEKKKQIEQKFAQID-- 607
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
EK + +E L E+ K + KM++++ +
Sbjct: 608 EKTEKAKEERLAEEKAKKKAAAKKMEEVEAR 638
Score = 32.0 bits (71), Expect = 1.3
Identities = 19/80 (23%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
Query: 403 KQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALR 462
+Q ++ + ++E+ F ++ + ++A + R E+K +K E+ E +R+ EE A R
Sbjct: 589 EQMKEEKKKQIEQKFAQIDE-KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 647
Query: 463 ---REQKKLEKKQMKMKQIK 479
+Q++ E++ ++ Q K
Sbjct: 648 LRWLQQEEEERRHQELLQKK 667
Score = 30.4 bits (67), Expect = 3.7
Identities = 18/77 (23%), Positives = 35/77 (45%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
+KF E +KA + R E+ K + +E R++E++ + EE+ +
Sbjct: 601 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 660
Query: 454 RRLEEAALRREQKKLEK 470
+ L + EQ++L K
Sbjct: 661 QELLQKKKEEEQERLRK 677
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 43.1 bits (100), Expect = 6e-04
Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 393 AKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP-- 450
A++ R +++ ++ R E + +RQ A Q RR E++R + ER + E +
Sbjct: 681 AEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKAL 740
Query: 451 -----EKQRRLEEAALRREQKKLEKKQMKMKQIK 479
+ QR LEE + EQ++L ++Q++ +Q K
Sbjct: 741 RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774
Score = 37.7 bits (86), Expect = 0.023
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 391 DKAKKFRLNREGKQK--ADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEE 448
+KAK+ RL E +K A K VE + +R Q EE++ E + EE
Sbjct: 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 666
Query: 449 DPEKQRRLEEAALRREQKKLEKKQMKMKQ 477
+ E+ R+ EA EQ++ E+++ + ++
Sbjct: 667 EQERLRKAAEAKRLAEQREQERREQERRE 695
Score = 35.0 bits (79), Expect = 0.15
Identities = 20/68 (29%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
Query: 414 EENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQM 473
E+ +L +++R+E A+ R +K +K R + E +++ RL + RE+ + + K+
Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVE-QMKEE 590
Query: 474 KMKQIKVK 481
K KQI+ K
Sbjct: 591 KKKQIEQK 598
Score = 34.3 bits (77), Expect = 0.26
Identities = 26/101 (25%), Positives = 54/101 (53%), Gaps = 15/101 (14%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSR---REEKKRAEKERIMNE 447
+K +K + R ++KA K A + ++ Q +EA + R +EE++R +E + +
Sbjct: 604 EKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKK 663
Query: 448 EDPEKQRRLEEAAL-----------RREQKKLEKKQMKMKQ 477
++ E+Q RL +AA RREQ++ E+++ + ++
Sbjct: 664 KE-EEQERLRKAAEAKRLAEQREQERREQERREQERREQER 703
Score = 33.1 bits (74), Expect = 0.58
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 9/81 (11%)
Query: 400 REGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKR-----AEKERIMNE----EDP 450
R +++ ++ R E + + QE Q+ RE ++R +KE++ E +
Sbjct: 698 RREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK 757
Query: 451 EKQRRLEEAALRREQKKLEKK 471
E+Q+RL E L+ EQ+K K+
Sbjct: 758 EEQQRLAERQLQEEQEKKAKE 778
Score = 32.7 bits (73), Expect = 0.75
Identities = 17/91 (18%), Positives = 50/91 (54%), Gaps = 4/91 (4%)
Query: 391 DKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDP 450
++ ++ ++ + +++ ++ + + EE K+ +Q +E + +EEKK+ +++ +
Sbjct: 548 EQLRRQKVEEDKRRRLEEVKLKREERLRKV--LQARERVEQMKEEKKKQIEQKFAQID-- 603
Query: 451 EKQRRLEEAALRREQKKLEKKQMKMKQIKVK 481
EK + +E L E+ K + KM++++ +
Sbjct: 604 EKTEKAKEERLAEEKAKKKAAAKKMEEVEAR 634
Score = 32.0 bits (71), Expect = 1.3
Identities = 19/74 (25%), Positives = 45/74 (60%), Gaps = 7/74 (9%)
Query: 413 VEENFLKLTHVQRQEAAQSRREE----KKRAEKERIMNEE-DPEKQRRLEEAALRREQ-- 465
V ++F+K R + + R+ +++ E E++ ++ + +K+RRLEE L+RE+
Sbjct: 515 VMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERL 574
Query: 466 KKLEKKQMKMKQIK 479
+K+ + + +++Q+K
Sbjct: 575 RKVLQARERVEQMK 588
Score = 32.0 bits (71), Expect = 1.3
Identities = 19/80 (23%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
Query: 403 KQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALR 462
+Q ++ + ++E+ F ++ + ++A + R E+K +K E+ E +R+ EE A R
Sbjct: 585 EQMKEEKKKQIEQKFAQIDE-KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
Query: 463 ---REQKKLEKKQMKMKQIK 479
+Q++ E++ ++ Q K
Sbjct: 644 LRWLQQEEEERRHQELLQKK 663
Score = 30.4 bits (67), Expect = 3.7
Identities = 18/77 (23%), Positives = 35/77 (45%)
Query: 394 KKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQ 453
+KF E +KA + R E+ K + +E R++E++ + EE+ +
Sbjct: 597 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 656
Query: 454 RRLEEAALRREQKKLEK 470
+ L + EQ++L K
Sbjct: 657 QELLQKKKEEEQERLRK 673
>gi|12711676 UPF3 regulator of nonsense transcripts homolog A
isoform hUpf3p [Homo sapiens]
Length = 476
Score = 43.1 bits (100), Expect = 6e-04
Identities = 20/66 (30%), Positives = 43/66 (65%), Gaps = 3/66 (4%)
Query: 417 FLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRRE---QKKLEKKQM 473
++K +++Q + +REE++R E E+ E+ +++RR EE ++E QKK+ +K++
Sbjct: 220 YIKNRKLEKQRIREEKREERRRRELEKKRLREEEKRRRREEERCKKKETDKQKKIAEKEV 279
Query: 474 KMKQIK 479
++K +K
Sbjct: 280 RIKLLK 285
Score = 30.0 bits (66), Expect = 4.9
Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Query: 404 QKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALR- 462
+K +K R R E+ + + E + R EEK+R +E +++ +KQ+++ E +R
Sbjct: 224 RKLEKQRIREEKR--EERRRRELEKKRLREEEKRRRREEERCKKKETDKQKKIAEKEVRI 281
Query: 463 REQKKLEK 470
+ KK EK
Sbjct: 282 KLLKKPEK 289
>gi|18375525 UPF3 regulator of nonsense transcripts homolog A
isoform hUpf3pdelta [Homo sapiens]
Length = 443
Score = 43.1 bits (100), Expect = 6e-04
Identities = 20/66 (30%), Positives = 43/66 (65%), Gaps = 3/66 (4%)
Query: 417 FLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRRE---QKKLEKKQM 473
++K +++Q + +REE++R E E+ E+ +++RR EE ++E QKK+ +K++
Sbjct: 187 YIKNRKLEKQRIREEKREERRRRELEKKRLREEEKRRRREEERCKKKETDKQKKIAEKEV 246
Query: 474 KMKQIK 479
++K +K
Sbjct: 247 RIKLLK 252
Score = 30.0 bits (66), Expect = 4.9
Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Query: 404 QKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALR- 462
+K +K R R E+ + + E + R EEK+R +E +++ +KQ+++ E +R
Sbjct: 191 RKLEKQRIREEKR--EERRRRELEKKRLREEEKRRRREEERCKKKETDKQKKIAEKEVRI 248
Query: 463 REQKKLEK 470
+ KK EK
Sbjct: 249 KLLKKPEK 256
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,893,588
Number of Sequences: 37866
Number of extensions: 861849
Number of successful extensions: 13361
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 314
Number of HSP's successfully gapped in prelim test: 457
Number of HSP's that attempted gapping in prelim test: 5987
Number of HSP's gapped (non-prelim): 5093
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.