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Search of human proteins with 17158023
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17158023 hypothetical protein LOC85395 [Homo sapiens]
(230 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17158023 hypothetical protein LOC85395 [Homo sapiens] 445 e-125
gi|169206039 PREDICTED: hypothetical protein [Homo sapiens] 311 2e-85
gi|113424287 PREDICTED: hypothetical protein [Homo sapiens] 311 2e-85
gi|113424103 PREDICTED: hypothetical protein [Homo sapiens] 311 2e-85
gi|239752538 PREDICTED: hypothetical protein, partial [Homo sapi... 292 1e-79
gi|113427727 PREDICTED: hypothetical protein [Homo sapiens] 292 1e-79
gi|169212923 PREDICTED: hypothetical protein [Homo sapiens] 290 7e-79
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 42 3e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 39 0.005
gi|148746195 trichohyalin [Homo sapiens] 38 0.008
gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens] 37 0.011
gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapi... 37 0.011
gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapi... 37 0.011
gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] 35 0.041
gi|239750672 PREDICTED: hypothetical protein [Homo sapiens] 35 0.041
gi|239744982 PREDICTED: hypothetical protein [Homo sapiens] 35 0.041
gi|112421108 capicua homolog [Homo sapiens] 35 0.041
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 35 0.041
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 35 0.041
gi|153945765 mitogen-activated protein kinase kinase kinase 1 [H... 35 0.054
gi|239751352 PREDICTED: hypothetical protein XP_002347815 [Homo ... 35 0.070
gi|239745851 PREDICTED: hypothetical protein XP_002343605 [Homo ... 35 0.070
gi|239740933 PREDICTED: hypothetical protein XP_002344111 [Homo ... 35 0.070
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 35 0.070
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 35 0.070
gi|118918413 MICAL C-terminal like [Homo sapiens] 34 0.092
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 34 0.092
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 34 0.092
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 34 0.092
gi|148612849 kinesin heavy chain member 2 isoform 2 [Homo sapiens] 34 0.092
>gi|17158023 hypothetical protein LOC85395 [Homo sapiens]
Length = 230
Score = 445 bits (1145), Expect = e-125
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 1 MGKVRGLRARVHQAAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDP 60
MGKVRGLRARVHQAAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDP
Sbjct: 1 MGKVRGLRARVHQAAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDP 60
Query: 61 SALVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIE 120
SALVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIE
Sbjct: 61 SALVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIE 120
Query: 121 AIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSR 180
AIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSR
Sbjct: 121 AIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSR 180
Query: 181 MSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQL 230
MSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQL
Sbjct: 181 MSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLEDGGQL 230
>gi|169206039 PREDICTED: hypothetical protein [Homo sapiens]
Length = 181
Score = 311 bits (798), Expect = 2e-85
Identities = 168/184 (91%), Positives = 168/184 (91%), Gaps = 15/184 (8%)
Query: 47 FINTNIFARTKIDPSALVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKE 106
FINTNIFARTKIDPSALVQKLELDVRSVTS IRRGAEAKTVLPKKE
Sbjct: 13 FINTNIFARTKIDPSALVQKLELDVRSVTS---------------IRRGAEAKTVLPKKE 57
Query: 107 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQAR 166
KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQ R
Sbjct: 58 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTR 117
Query: 167 SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED 226
SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED
Sbjct: 118 SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED 177
Query: 227 GGQL 230
GGQL
Sbjct: 178 GGQL 181
>gi|113424287 PREDICTED: hypothetical protein [Homo sapiens]
Length = 181
Score = 311 bits (798), Expect = 2e-85
Identities = 168/184 (91%), Positives = 168/184 (91%), Gaps = 15/184 (8%)
Query: 47 FINTNIFARTKIDPSALVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKE 106
FINTNIFARTKIDPSALVQKLELDVRSVTS IRRGAEAKTVLPKKE
Sbjct: 13 FINTNIFARTKIDPSALVQKLELDVRSVTS---------------IRRGAEAKTVLPKKE 57
Query: 107 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQAR 166
KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQ R
Sbjct: 58 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTR 117
Query: 167 SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED 226
SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED
Sbjct: 118 SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED 177
Query: 227 GGQL 230
GGQL
Sbjct: 178 GGQL 181
>gi|113424103 PREDICTED: hypothetical protein [Homo sapiens]
Length = 181
Score = 311 bits (798), Expect = 2e-85
Identities = 168/184 (91%), Positives = 168/184 (91%), Gaps = 15/184 (8%)
Query: 47 FINTNIFARTKIDPSALVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKE 106
FINTNIFARTKIDPSALVQKLELDVRSVTS IRRGAEAKTVLPKKE
Sbjct: 13 FINTNIFARTKIDPSALVQKLELDVRSVTS---------------IRRGAEAKTVLPKKE 57
Query: 107 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQAR 166
KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQ R
Sbjct: 58 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQTR 117
Query: 167 SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED 226
SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED
Sbjct: 118 SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED 177
Query: 227 GGQL 230
GGQL
Sbjct: 178 GGQL 181
>gi|239752538 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 172
Score = 292 bits (748), Expect = 1e-79
Identities = 162/184 (88%), Positives = 163/184 (88%), Gaps = 15/184 (8%)
Query: 47 FINTNIFARTKIDPSALVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKE 106
FINTNIFARTKIDPSALVQKLELDVRSVTS IRRGAEAKTVLPKKE
Sbjct: 4 FINTNIFARTKIDPSALVQKLELDVRSVTS---------------IRRGAEAKTVLPKKE 48
Query: 107 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQAR 166
KMKLRREQ LQKIEAIKLAEQKHREERRRRATVVVG LHPLRDALPELLGLEAGSRRQA
Sbjct: 49 KMKLRREQCLQKIEAIKLAEQKHREERRRRATVVVGHLHPLRDALPELLGLEAGSRRQAC 108
Query: 167 SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED 226
SRESNKP PSELSRMSAAQRQQLLEE RTRFQELL+SPAYRAS LVAIGQTLARQMQLED
Sbjct: 109 SRESNKPWPSELSRMSAAQRQQLLEEGRTRFQELLSSPAYRASTLVAIGQTLARQMQLED 168
Query: 227 GGQL 230
GGQL
Sbjct: 169 GGQL 172
>gi|113427727 PREDICTED: hypothetical protein [Homo sapiens]
Length = 181
Score = 292 bits (748), Expect = 1e-79
Identities = 162/184 (88%), Positives = 163/184 (88%), Gaps = 15/184 (8%)
Query: 47 FINTNIFARTKIDPSALVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKE 106
FINTNIFARTKIDPSALVQKLELDVRSVTS IRRGAEAKTVLPKKE
Sbjct: 13 FINTNIFARTKIDPSALVQKLELDVRSVTS---------------IRRGAEAKTVLPKKE 57
Query: 107 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQAR 166
KMKLRREQ LQKIEAIKLAEQKHREERRRRATVVVG LHPLRDALPELLGLEAGSRRQA
Sbjct: 58 KMKLRREQCLQKIEAIKLAEQKHREERRRRATVVVGHLHPLRDALPELLGLEAGSRRQAC 117
Query: 167 SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED 226
SRESNKP PSELSRMSAAQRQQLLEE RTRFQELL+SPAYRAS LVAIGQTLARQMQLED
Sbjct: 118 SRESNKPWPSELSRMSAAQRQQLLEEGRTRFQELLSSPAYRASTLVAIGQTLARQMQLED 177
Query: 227 GGQL 230
GGQL
Sbjct: 178 GGQL 181
>gi|169212923 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 290 bits (742), Expect = 7e-79
Identities = 160/184 (86%), Positives = 162/184 (88%), Gaps = 15/184 (8%)
Query: 47 FINTNIFARTKIDPSALVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKE 106
FINTNIFARTKIDPSALVQKLELDVRSVTS IRRGAEAKT+LPKKE
Sbjct: 34 FINTNIFARTKIDPSALVQKLELDVRSVTS---------------IRRGAEAKTILPKKE 78
Query: 107 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQAR 166
KMKLRREQ LQKIEAIKLAEQKHREERRRRATVVVG LHPLRDALPELLGLEAGSR QA
Sbjct: 79 KMKLRREQCLQKIEAIKLAEQKHREERRRRATVVVGHLHPLRDALPELLGLEAGSRHQAC 138
Query: 167 SRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLED 226
SRESNKP PSELSRMSAAQRQQLLEE RTRFQELL+SPAYRAS LVAIGQTLARQMQLED
Sbjct: 139 SRESNKPWPSELSRMSAAQRQQLLEEGRTRFQELLSSPAYRASTLVAIGQTLARQMQLED 198
Query: 227 GGQL 230
GGQL
Sbjct: 199 GGQL 202
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 42.4 bits (98), Expect = 3e-04
Identities = 56/200 (28%), Positives = 81/200 (40%), Gaps = 25/200 (12%)
Query: 3 KVRGLRARVHQAAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDPSA 62
K R +V +A V + A P P AP P PASA + A + A
Sbjct: 399 KGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAP------ASAPAPAPVPTPA 452
Query: 63 LVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAI 122
+V V + SV+ S+ + P EA +L EK +L REQ ++
Sbjct: 453 MVSAPSSTVNASASVKT----SAGTTDPE-----EATRLL--AEKRRLAREQREKEERER 501
Query: 123 KLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSE---LS 179
+ E+ R++R A V + R+ E LEA QAR +E R +E L
Sbjct: 502 REQEELERQKREELAQRVAEERTTRRE--EESRRLEA---EQAREKEEQLQRQAEERALR 556
Query: 180 RMSAAQRQQLLEEERTRFQE 199
A+R Q +EE R +E
Sbjct: 557 EREEAERAQRQKEEEARVRE 576
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 38.5 bits (88), Expect = 0.005
Identities = 45/198 (22%), Positives = 74/198 (37%), Gaps = 27/198 (13%)
Query: 18 PKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDPSALVQKLELDVRSVTSV 77
P G+ P PAPP E+ A + G + P S T+V
Sbjct: 71 PSGQVGPRPAPPQEESPSSEAKSRGP----------TPPAMGPRDARPPRRSSQPSPTAV 120
Query: 78 RRGEAGSSARSVPSIRRGAEAKTVLPKKEK----MKLRREQWLQKIEAIKLAEQKHREER 133
++ + + V + G K ++E+ + ++ WL+K E K +K +ER
Sbjct: 121 PASDSPPTKQEVK--KAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQER 178
Query: 134 RRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLLEEE 193
RRR R AL E RQ + E NK R + S + + ++
Sbjct: 179 RRRLEEQRLKAEQRRAALEE---------RQRQKLEKNKERYEAAIQRSVKKTWAEIRQQ 229
Query: 194 RTRFQELL--ASPAYRAS 209
R + L +SP ++ S
Sbjct: 230 RWSWAGALHHSSPGHKTS 247
Score = 37.0 bits (84), Expect = 0.014
Identities = 49/204 (24%), Positives = 78/204 (38%), Gaps = 15/204 (7%)
Query: 3 KVRGLRARVHQAAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDPSA 62
K R + A P AP P P P+ PPA D A + + + PS
Sbjct: 530 KRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETP-TDAAVLTSPPAPAPPVTPSK 588
Query: 63 LVQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIE-- 120
+ D T + R R E + L + ++R EQ ++ E
Sbjct: 589 PMAG-TTDREEATRL----LAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEAR 643
Query: 121 AIKLAEQKHREER--RRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSEL 178
A + AE + REE+ R +A + L+ E EA SR +A + + + +
Sbjct: 644 AEREAEARRREEQEAREKAQAEQEEQERLQKQKEE---AEARSREEAERQRLEREKHFQQ 700
Query: 179 SRMSAAQRQQLLEE--ERTRFQEL 200
+R++ LEE +RTR E+
Sbjct: 701 QEQERQERRKRLEEIMKRTRKSEV 724
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 37.7 bits (86), Expect = 0.008
Identities = 41/161 (25%), Positives = 66/161 (40%), Gaps = 17/161 (10%)
Query: 68 ELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQ 127
E +R +RR + R +RR + + + + +LRREQ L++ + + EQ
Sbjct: 380 EQQLRREQQLRREQ---QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQ 436
Query: 128 KHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQ 187
KH +ERR + + + RD L R + R + R +L R +R+
Sbjct: 437 KHEQERREQR--LKREQEERRDWL---------KREEETERHEQERRKQQLKRDQEEERR 485
Query: 188 Q---LLEEERTRFQELLASPAYRASPLVAIGQTLARQMQLE 225
+ LEEE R Q+ R Q L RQ + E
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEE 526
Score = 35.8 bits (81), Expect = 0.032
Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 4/102 (3%)
Query: 104 KKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLR----DALPELLGLEA 159
K+++ + RRE+WL+ E + +Q+ RE++ RR + R + L + L E
Sbjct: 477 KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ 536
Query: 160 GSRRQARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELL 201
RR+ R + E R+ +R+Q L+ E+ ++ L
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
Score = 33.9 bits (76), Expect = 0.12
Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 20/119 (16%)
Query: 87 RSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHP 146
R + + R + LP++E+ + RR Q ++ + ++ E++ + +RR RA L
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQ----QLQE 851
Query: 147 LRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPA 205
D L +E + R S+ R R QL EE + R L A PA
Sbjct: 852 EEDGL----------------QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA 894
Score = 32.7 bits (73), Expect = 0.27
Identities = 30/121 (24%), Positives = 49/121 (40%), Gaps = 4/121 (3%)
Query: 79 RGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRAT 138
R E R R E + + + +LRREQ L++ + ++ +Q RE++ RR
Sbjct: 352 RREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 411
Query: 139 VVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQ 198
+ + R+ + L E R + E + R L R +R L EE T
Sbjct: 412 QLRREQQLRRE---QQLRREQEEERHEQKHEQER-REQRLKREQEERRDWLKREEETERH 467
Query: 199 E 199
E
Sbjct: 468 E 468
Score = 32.7 bits (73), Expect = 0.27
Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 8/121 (6%)
Query: 87 RSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHP 146
R +RR + + + + +LRREQ L++ + ++ +Q RE++ RR + +
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 147 LR-------DALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQE 199
R + + L E RR RE R + R +R Q EE R R+ +
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ-EEERRERWLK 490
Query: 200 L 200
L
Sbjct: 491 L 491
Score = 32.3 bits (72), Expect = 0.35
Identities = 36/143 (25%), Positives = 57/143 (39%), Gaps = 15/143 (10%)
Query: 103 PKKEKMKLRREQWLQKIEAIKLAEQKHREER-----------RRRATVVVGDLHPLRDAL 151
P++++ E+ L+K+E +L ++ EE+ RR+ + R
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Query: 152 PELLGLEAGSRRQARSRESNKPRPSELSRMSAAQR--QQLL--EEERTRFQELLASPAYR 207
E + R Q RE + R +L R +R QQL +EE R Q+L R
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Query: 208 ASPLVAIGQTLARQMQLEDGGQL 230
+ Q L R+ QL QL
Sbjct: 385 REQQLRREQQLRREQQLRREQQL 407
Score = 32.3 bits (72), Expect = 0.35
Identities = 29/107 (27%), Positives = 50/107 (46%), Gaps = 20/107 (18%)
Query: 104 KKEKMKLRREQ-----WLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLE 158
++ + +L+REQ WL++ E + EQ+ R+++ +R + L LE
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR--------DQEEERRERWLKLE 492
Query: 159 AGSRRQARSRESNKPRPSELSRMSAAQRQQLL--EEERTRFQELLAS 203
RR+ + R R +L R +R+Q L +EE R Q+ L S
Sbjct: 493 EEERREQQER-----REQQLRREQEERREQRLKRQEEEERLQQRLRS 534
Score = 32.3 bits (72), Expect = 0.35
Identities = 24/109 (22%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Query: 93 RRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALP 152
RR + + ++ + +L+R++ ++++ +EQ+ R E+ R ++ R
Sbjct: 502 RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR---- 557
Query: 153 ELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELL 201
LE R Q RE + R L R ++Q+L E+ R ++ L
Sbjct: 558 ----LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602
Score = 32.3 bits (72), Expect = 0.35
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 8/96 (8%)
Query: 105 KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQ 164
+ + +LRREQ ++ + +K E+K E+ RR + + +LL E R+Q
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRL----KREQEERRDQLLKREEERRQQ 588
Query: 165 ARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQEL 200
RE + L R + + LE+E R Q L
Sbjct: 589 RLKREQEERLEQRLKR----EEVERLEQEERREQRL 620
Score = 31.6 bits (70), Expect = 0.59
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 103 PKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDAL---PELLGLEA 159
P+K + + R +++ ++ E + EQ REER +R + +D L E L E
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 160 GSRRQARSRESNKPRPSELSRMSAAQRQQLLEEER--TRFQEL 200
+R+ + RE EL + + +QLL EER R QEL
Sbjct: 1038 REKRRLQERERQYREEEELQQ----EEEQLLGEERETRRRQEL 1076
Score = 31.2 bits (69), Expect = 0.78
Identities = 38/148 (25%), Positives = 53/148 (35%), Gaps = 29/148 (19%)
Query: 81 EAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRR----- 135
EA + V S R E + ++E+ + RRE LQ E + Q+ EE+RR
Sbjct: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ 770
Query: 136 --------RATVVVGDLHPLRDALPELLGLEAGS----------------RRQARSRESN 171
R + PLR+ L E RRQ R RE
Sbjct: 771 WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE 830
Query: 172 KPRPSELSRMSAAQRQQLLEEERTRFQE 199
E ++ +R Q L+EE QE
Sbjct: 831 LQFLEEEEQLQRRERAQQLQEEEDGLQE 858
Score = 30.4 bits (67), Expect = 1.3
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 8/136 (5%)
Query: 93 RRGAEAKTVLPKKEKMKLRREQ----WLQKIEAIKLAEQKHREERRRRATVVVGDLHPLR 148
R+G E K ++ + ++ +E+ W ++ ++ E+K +EE +R +L
Sbjct: 220 RKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR----ELQEEE 275
Query: 149 DALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRA 208
+ L +L E RQ ++ + R + R + ++ +EER QE R
Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335
Query: 209 SPLVAIGQTLARQMQL 224
+ Q R+ QL
Sbjct: 336 EQQLRREQEERREQQL 351
Score = 30.4 bits (67), Expect = 1.3
Identities = 37/167 (22%), Positives = 64/167 (38%), Gaps = 39/167 (23%)
Query: 64 VQKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIK 123
V++LE + R ++R E R + + E + ++ + +LRREQ ++ + +K
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQ--QLLKSEEQE----ERRQQQLRREQQERREQRLK 660
Query: 124 LAEQKHR---------EERRRRATVVVGDLHPLRDALPELL------------------- 155
E++ R EE RR + + R+ + +
Sbjct: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
Query: 156 ---GLEAGSRRQARSRESNKPRPSEL--SRMSAAQRQQLLEEERTRF 197
+ G RR+ E + R SEL A RQQ EE+R F
Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDF 767
Score = 29.6 bits (65), Expect = 2.3
Identities = 31/136 (22%), Positives = 51/136 (37%), Gaps = 14/136 (10%)
Query: 78 RRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRA 137
RR E R + + E + + ++ K R E+ + + K E++ R R+ R
Sbjct: 1330 RRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE 1389
Query: 138 TVVVGDLHPLR----------DALPELLGLEAGSRRQARSR----ESNKPRPSELSRMSA 183
+ + LR D + E RQ R R E + R E R
Sbjct: 1390 RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFL 1449
Query: 184 AQRQQLLEEERTRFQE 199
+ QQL +E +F+E
Sbjct: 1450 EEEQQLRQERHRKFRE 1465
Score = 28.9 bits (63), Expect = 3.9
Identities = 32/155 (20%), Positives = 57/155 (36%), Gaps = 22/155 (14%)
Query: 71 VRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHR 130
+R +RR + R E + ++ + +LRREQ ++ + ++ +++ R
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 131 EERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLL 190
E++ R E R Q RE R +L R +R+Q L
Sbjct: 360 REQQLRRE------------------QEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Query: 191 EEERTRFQELLASPAYRASPLVAIGQTLARQMQLE 225
E Q+L R + Q L R+ + E
Sbjct: 402 RRE----QQLRREQQLRREQQLRREQQLRREQEEE 432
Score = 28.1 bits (61), Expect = 6.6
Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 17/160 (10%)
Query: 78 RRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRRE----QWLQKIEAIKLAEQKHREE- 132
RR E R +++ E L ++E+ K RR+ Q+ ++ E + EQ REE
Sbjct: 1102 RRQERERQCREEEELQQEEEQ---LLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158
Query: 133 ---RRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQL 189
RR+ + L+ +LL E RRQ R R+ + EL R QR +
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE--EEELQRQKRKQRYR- 1215
Query: 190 LEEERTRFQ---ELLASPAYRASPLVAIGQTLARQMQLED 226
E++R+ + E A R + + G+ + QLED
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255
Score = 27.7 bits (60), Expect = 8.6
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 4/129 (3%)
Query: 68 ELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQ 127
E +R R E R R E + + + + RREQ L++ + + EQ
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Query: 128 KHR--EERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQ 185
+ R +E RR + + R+ +L + R Q RE R +L R +
Sbjct: 363 QLRREQEEERREQQLRREQQLRRE--QQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 186 RQQLLEEER 194
R+Q L E+
Sbjct: 421 REQQLRREQ 429
Score = 27.7 bits (60), Expect = 8.6
Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 7/93 (7%)
Query: 109 KLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGS-RRQARS 167
+LR+EQ L + E +L ++ + RR+ + L+ +LL E RRQ R
Sbjct: 898 QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
Query: 168 RESNKPRPSELSRMSAAQRQQLLEE-ERTRFQE 199
R+ K + ++ + Q L EE E+ R QE
Sbjct: 958 RQYRKDK-----KLQQKEEQLLGEEPEKRRRQE 985
>gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens]
Length = 1486
Score = 37.4 bits (85), Expect = 0.011
Identities = 41/172 (23%), Positives = 69/172 (40%), Gaps = 22/172 (12%)
Query: 57 KIDPSALVQKLELDV-RSVTSVRRGEAGSSARSVPSIRRGAEAKTVL------PKKEKMK 109
K P+ + QK + D R ++ + R G + ++ G + KT+L P KEK +
Sbjct: 582 KETPTQVYQKDKQDADRPLSKMNRAVNGET------LKTGGDNKTLLHLGSSAPGKEKSE 635
Query: 110 LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRE 169
+E L K KL +Q+ REE P + + + G R + +E
Sbjct: 636 TDKETSLVKQTLAKLQQQEQREE---------AQWTPTKLSSKNVSGQTDKCREETFKQE 686
Query: 170 SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQ 221
S P + S R E +R + +E+L S + ++L RQ
Sbjct: 687 SQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQ 738
>gi|109255228 centrosomal protein 170kDa isoform alpha [Homo
sapiens]
Length = 1584
Score = 37.4 bits (85), Expect = 0.011
Identities = 41/172 (23%), Positives = 69/172 (40%), Gaps = 22/172 (12%)
Query: 57 KIDPSALVQKLELDV-RSVTSVRRGEAGSSARSVPSIRRGAEAKTVL------PKKEKMK 109
K P+ + QK + D R ++ + R G + ++ G + KT+L P KEK +
Sbjct: 680 KETPTQVYQKDKQDADRPLSKMNRAVNGET------LKTGGDNKTLLHLGSSAPGKEKSE 733
Query: 110 LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRE 169
+E L K KL +Q+ REE P + + + G R + +E
Sbjct: 734 TDKETSLVKQTLAKLQQQEQREE---------AQWTPTKLSSKNVSGQTDKCREETFKQE 784
Query: 170 SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQ 221
S P + S R E +R + +E+L S + ++L RQ
Sbjct: 785 SQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQ 836
>gi|109255232 centrosomal protein 170kDa isoform gamma [Homo
sapiens]
Length = 1460
Score = 37.4 bits (85), Expect = 0.011
Identities = 41/172 (23%), Positives = 69/172 (40%), Gaps = 22/172 (12%)
Query: 57 KIDPSALVQKLELDV-RSVTSVRRGEAGSSARSVPSIRRGAEAKTVL------PKKEKMK 109
K P+ + QK + D R ++ + R G + ++ G + KT+L P KEK +
Sbjct: 582 KETPTQVYQKDKQDADRPLSKMNRAVNGET------LKTGGDNKTLLHLGSSAPGKEKSE 635
Query: 110 LRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRE 169
+E L K KL +Q+ REE P + + + G R + +E
Sbjct: 636 TDKETSLVKQTLAKLQQQEQREE---------AQWTPTKLSSKNVSGQTDKCREETFKQE 686
Query: 170 SNKPRPSELSRMSAAQRQQLLEEERTRFQELLASPAYRASPLVAIGQTLARQ 221
S P + S R E +R + +E+L S + ++L RQ
Sbjct: 687 SQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQ 738
>gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]
Length = 625
Score = 35.4 bits (80), Expect = 0.041
Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 9/124 (7%)
Query: 77 VRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRRE------QWLQKIEAIKLAEQKHR 130
VR+ A R VP R A + +E++ L + QW +++ + +++ R
Sbjct: 337 VRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQW--ELQRVHAKQRRER 394
Query: 131 EERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLL 190
EER ++ + G + E G R+A R + SE R A+RQ LL
Sbjct: 395 EEREKQRALEQGR-RAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAERQGLL 453
Query: 191 EEER 194
ER
Sbjct: 454 RRER 457
>gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]
Length = 627
Score = 35.4 bits (80), Expect = 0.041
Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 9/124 (7%)
Query: 77 VRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRRE------QWLQKIEAIKLAEQKHR 130
VR+ A R VP R A + +E++ L + QW +++ + +++ R
Sbjct: 339 VRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQW--ELQRVHAKQRRER 396
Query: 131 EERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLL 190
EER ++ + G + E G R+A R + SE R A+RQ LL
Sbjct: 397 EEREKQRALEQGR-RAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAERQGLL 455
Query: 191 EEER 194
ER
Sbjct: 456 RRER 459
>gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]
Length = 627
Score = 35.4 bits (80), Expect = 0.041
Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 9/124 (7%)
Query: 77 VRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRRE------QWLQKIEAIKLAEQKHR 130
VR+ A R VP R A + +E++ L + QW +++ + +++ R
Sbjct: 339 VRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQW--ELQRVHAKQRRER 396
Query: 131 EERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLL 190
EER ++ + G + E G R+A R + SE R A+RQ LL
Sbjct: 397 EEREKQRALEQGR-RAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAERQGLL 455
Query: 191 EEER 194
ER
Sbjct: 456 RRER 459
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 35.4 bits (80), Expect = 0.041
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 14 AAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDPSALVQKLELDVRS 73
A + PKG AP A PAP + P A+A ++ + + P A QK++ + S
Sbjct: 1131 ATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPK---AQRPSPKA-PQKVKAAIAS 1186
Query: 74 VTSVRRGEAGSSARSVPSIRRGAE 97
+ V EAG+S R P+ R+ E
Sbjct: 1187 I-PVGSFEAGASGRPGPAPRQPLE 1209
Score = 32.0 bits (71), Expect = 0.46
Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 9/45 (20%)
Query: 3 KVRGLRARVHQAAV---RPKGEAAPGPAPP------APEATPPPA 38
K+R +R ++ QAA +P G AP P PP AP TP PA
Sbjct: 1510 KIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPA 1554
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 35.4 bits (80), Expect = 0.041
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 15/103 (14%)
Query: 104 KKEKMKLRREQWLQKIEAIK-----LAEQKHREERRRRATVVVGDLHPLRDALPELLGLE 158
+K++ + RR +WLQ+ E + L ++K E+ R R L R+
Sbjct: 639 RKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ-------- 690
Query: 159 AGSRRQARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELL 201
RR+ RE + + Q +QL E+ER R QE L
Sbjct: 691 --ERREQERREQERREQERREQERREQERQLAEQERRREQERL 731
Score = 33.1 bits (74), Expect = 0.20
Identities = 29/125 (23%), Positives = 61/125 (48%), Gaps = 18/125 (14%)
Query: 91 SIRRGAEAKTVLPKK---------EKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVV 141
++RR EA+ + +K E++KL+RE+ L+K+ + ++ +EE++++
Sbjct: 544 NLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF 603
Query: 142 GDLHPLRDALPELLGLEAGSRRQARSR-----ESNKPRPSELSRMSAAQRQQLLEEERTR 196
+ + E E ++++A ++ E+ + + E R+ Q+ EEE R
Sbjct: 604 AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ----EEEERR 659
Query: 197 FQELL 201
QELL
Sbjct: 660 HQELL 664
Score = 30.8 bits (68), Expect = 1.0
Identities = 25/108 (23%), Positives = 45/108 (41%)
Query: 92 IRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDAL 151
+R+ AEAK + ++E+ + +E+ Q+ + EQ+ RE+ R+ A A
Sbjct: 675 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 734
Query: 152 PELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQE 199
EL E R Q + + +QL EE+ + +E
Sbjct: 735 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 782
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 35.4 bits (80), Expect = 0.041
Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 15/103 (14%)
Query: 104 KKEKMKLRREQWLQKIEAIK-----LAEQKHREERRRRATVVVGDLHPLRDALPELLGLE 158
+K++ + RR +WLQ+ E + L ++K E+ R R L R+
Sbjct: 635 RKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ-------- 686
Query: 159 AGSRRQARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQELL 201
RR+ RE + + Q +QL E+ER R QE L
Sbjct: 687 --ERREQERREQERREQERREQERREQERQLAEQERRREQERL 727
Score = 30.8 bits (68), Expect = 1.0
Identities = 25/108 (23%), Positives = 45/108 (41%)
Query: 92 IRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDAL 151
+R+ AEAK + ++E+ + +E+ Q+ + EQ+ RE+ R+ A A
Sbjct: 671 LRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE 730
Query: 152 PELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQE 199
EL E R Q + + +QL EE+ + +E
Sbjct: 731 RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
Score = 30.4 bits (67), Expect = 1.3
Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 14/127 (11%)
Query: 105 KEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQ 164
KEK + R E +K EA +L QK E++RRR V L E R+
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEV-------------KLKREERLRKV 577
Query: 165 ARSRESNKPRPSELSRMSAAQRQQLLEE-ERTRFQELLASPAYRASPLVAIGQTLARQMQ 223
++RE + E + + Q+ E+ E+ + + L A + + + + AR+ Q
Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 637
Query: 224 LEDGGQL 230
E+ +L
Sbjct: 638 EEEARRL 644
>gi|153945765 mitogen-activated protein kinase kinase kinase 1 [Homo
sapiens]
Length = 1512
Score = 35.0 bits (79), Expect = 0.054
Identities = 45/181 (24%), Positives = 62/181 (34%), Gaps = 27/181 (14%)
Query: 14 AAVRPKGEAAPGPAPP---------APEATPPPASAAGKDWAFINTNIFARTKIDPSALV 64
AA P +P P P P A PPP AA + A + ++ A S
Sbjct: 81 AASPPASSTSPSPEPADAAGSGTGFQPVAVPPPHGAASRGGAHLTESVAAPDSGASSPAA 140
Query: 65 QKLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWL--QKIEAI 122
+ +R A + + R E K L KM R E+ + +K++A
Sbjct: 141 AE--------PGEKRAPAAEPSPAAAPAGREMENKETLKGLHKMDDRPEERMIREKLKAT 192
Query: 123 KLAEQKHR--EERRRRATVVV------GDLHPLRDALPELLGLEAGSRRQARSRESNKPR 174
+ KH E R RR VVV GD + E G S S+ P
Sbjct: 193 CMPAWKHEWLERRNRRGPVVVKPIPVKGDGSEMNHLAAESPGEVQASAASPASKGRRSPS 252
Query: 175 P 175
P
Sbjct: 253 P 253
>gi|239751352 PREDICTED: hypothetical protein XP_002347815 [Homo
sapiens]
Length = 697
Score = 34.7 bits (78), Expect = 0.070
Identities = 56/206 (27%), Positives = 77/206 (37%), Gaps = 33/206 (16%)
Query: 8 RARVHQAAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDPSA-LVQK 66
RA HQ + PGP PP T D A + + ++ A L+ K
Sbjct: 257 RAEAHQLLPSLRPVPVPGPRPPQASGT--------FDVALLPQRLQCGPPLEELAELLPK 308
Query: 67 LELDVRSVTSVRRGEAGSSARSVP--SIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKL 124
LD +S + GSSA +P S RRG E P E + Q ++A+
Sbjct: 309 RSLDPKSTLLLSLSSGGSSADWIPIASERRGLE-----PAAEAL----GSAYQLLDALSN 359
Query: 125 AEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAA 184
++ R VV+ HPL L EAGS R S+ P P + A
Sbjct: 360 GLMPGADDGLR---VVLDQAHPLAFWSLRLWEQEAGSE---ALRGSSAPHPLVPGAVGAE 413
Query: 185 QRQQLLEEERTRFQELLASPAYRASP 210
+ L E+E + S A R SP
Sbjct: 414 GVRGLWEQE-------VGSKALRGSP 432
>gi|239745851 PREDICTED: hypothetical protein XP_002343605 [Homo
sapiens]
Length = 500
Score = 34.7 bits (78), Expect = 0.070
Identities = 56/206 (27%), Positives = 77/206 (37%), Gaps = 33/206 (16%)
Query: 8 RARVHQAAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDPSA-LVQK 66
RA HQ + PGP PP T D A + + ++ A L+ K
Sbjct: 257 RAEAHQLLPSLRPVPVPGPRPPQASGT--------FDVALLPQRLQCGPPLEELAELLPK 308
Query: 67 LELDVRSVTSVRRGEAGSSARSVP--SIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKL 124
LD +S + GSSA +P S RRG E P E + Q ++A+
Sbjct: 309 RSLDPKSTLLLSLSSGGSSADWIPIASERRGLE-----PAAEAL----GSAYQLLDALSN 359
Query: 125 AEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAA 184
++ R VV+ HPL L EAGS R S+ P P + A
Sbjct: 360 GLMPGADDGLR---VVLDQAHPLAFWSLRLWEQEAGSE---ALRGSSAPHPLVPGAVGAE 413
Query: 185 QRQQLLEEERTRFQELLASPAYRASP 210
+ L E+E + S A R SP
Sbjct: 414 GVRGLWEQE-------VGSKALRGSP 432
>gi|239740933 PREDICTED: hypothetical protein XP_002344111 [Homo
sapiens]
Length = 697
Score = 34.7 bits (78), Expect = 0.070
Identities = 56/206 (27%), Positives = 77/206 (37%), Gaps = 33/206 (16%)
Query: 8 RARVHQAAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDPSA-LVQK 66
RA HQ + PGP PP T D A + + ++ A L+ K
Sbjct: 257 RAEAHQLLPSLRPVPVPGPRPPQASGT--------FDVALLPQRLQCGPPLEELAELLPK 308
Query: 67 LELDVRSVTSVRRGEAGSSARSVP--SIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKL 124
LD +S + GSSA +P S RRG E P E + Q ++A+
Sbjct: 309 RSLDPKSTLLLSLSSGGSSADWIPIASERRGLE-----PAAEAL----GSAYQLLDALSN 359
Query: 125 AEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAA 184
++ R VV+ HPL L EAGS R S+ P P + A
Sbjct: 360 GLMPGADDGLR---VVLDQAHPLAFWSLRLWEQEAGSE---ALRGSSAPHPLVPGAVGAE 413
Query: 185 QRQQLLEEERTRFQELLASPAYRASP 210
+ L E+E + S A R SP
Sbjct: 414 GVRGLWEQE-------VGSKALRGSP 432
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 34.7 bits (78), Expect = 0.070
Identities = 30/134 (22%), Positives = 55/134 (41%), Gaps = 13/134 (9%)
Query: 66 KLELDVRSVTSVRRGEAGSSARSVPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLA 125
K E D + R EA A + RR AE + + ++EK Q +++ E
Sbjct: 281 KAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAE 340
Query: 126 EQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQ 185
E++ +E +RA E ++ +R A R+ + E +++ +
Sbjct: 341 ERQRIKEEEKRAA-------------EERQRIKEEEKRAAEERQRARAEEEEKAKVEEQK 387
Query: 186 RQQLLEEERTRFQE 199
R + LEE++ QE
Sbjct: 388 RNKQLEEKKHAMQE 401
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 34.7 bits (78), Expect = 0.070
Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 15/103 (14%)
Query: 107 KMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQAR 166
K KLR EQ ++ +E E+K R + R + GDL ++++ + ++ + +
Sbjct: 1071 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVAD------AAQDKQQ 1124
Query: 167 SRESNKPRPSELSRMS---------AAQRQQLLEEERTRFQEL 200
E K + SELS++S AQ Q+ ++E + R +EL
Sbjct: 1125 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEEL 1167
Score = 32.7 bits (73), Expect = 0.27
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 10/92 (10%)
Query: 104 KKEKMKLRREQWLQKIEAIKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRR 163
K ++++ R E+ +++EA + A + ++R A +L L + L E G AG R
Sbjct: 1156 KIKELQARAEELEEELEAERAARARVEKQRAEAAR----ELEELSERLEEAGGASAGQRE 1211
Query: 164 QARSRESNKPRPSELSRMSAAQRQQLLEEERT 195
R RE +EL R+ + L E T
Sbjct: 1212 GCRKRE------AELGRLRRELEEAALRHEAT 1237
>gi|118918413 MICAL C-terminal like [Homo sapiens]
Length = 695
Score = 34.3 bits (77), Expect = 0.092
Identities = 45/153 (29%), Positives = 62/153 (40%), Gaps = 34/153 (22%)
Query: 21 EAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDPSALVQKLELDVRSVTSVRRG 80
+AAP P PP P PPP +A G D + N R ++
Sbjct: 454 QAAPPP-PPPPPPPPPPPTAGGAD----SKNFPLRAQVT--------------------- 487
Query: 81 EAGSSARSVPSIRRGAE--AKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHREERRRRAT 138
EA SSA S S E + L KEK LRR + L+K A+K ++ +R +A
Sbjct: 488 EASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEK--AMKQLVKQEELKRLYKAQ 545
Query: 139 VVVGDLHPL--RDALPELLG--LEAGSRRQARS 167
+ L + R E+ G LE R +A S
Sbjct: 546 AIQRQLEEVEERQRASEIQGVRLEKALRGEADS 578
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 34.3 bits (77), Expect = 0.092
Identities = 47/200 (23%), Positives = 77/200 (38%), Gaps = 43/200 (21%)
Query: 11 VHQAAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDPSALVQKLEL- 69
+H + G+ P PP PP+ GK IN + + K+ +KL +
Sbjct: 306 MHLTDMAKAGQPLPLTLPPE---LVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVT 362
Query: 70 -DVRSVTSVRRGEAGSSARS---VPSIRRGAEAKTVLPKKE----KMKLRREQWLQKIEA 121
+ + + RG R + +R AE K K+E + +L+ ++W +++E
Sbjct: 363 FEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLEL 422
Query: 122 IKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRM 181
K E++ ER+R E R+ RE+ K
Sbjct: 423 EKRLEKQRELERQR----------------------EEERRKDIERREAAK--------- 451
Query: 182 SAAQRQQLLEEERTRFQELL 201
+RQ+ LE ER R QELL
Sbjct: 452 QELERQRRLEWERIRRQELL 471
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 34.3 bits (77), Expect = 0.092
Identities = 47/200 (23%), Positives = 77/200 (38%), Gaps = 43/200 (21%)
Query: 11 VHQAAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDPSALVQKLEL- 69
+H + G+ P PP PP+ GK IN + + K+ +KL +
Sbjct: 306 MHLTDMAKAGQPLPLTLPPE---LVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVT 362
Query: 70 -DVRSVTSVRRGEAGSSARS---VPSIRRGAEAKTVLPKKE----KMKLRREQWLQKIEA 121
+ + + RG R + +R AE K K+E + +L+ ++W +++E
Sbjct: 363 FEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLEL 422
Query: 122 IKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRM 181
K E++ ER+R E R+ RE+ K
Sbjct: 423 EKRLEKQRELERQR----------------------EEERRKDIERREAAK--------- 451
Query: 182 SAAQRQQLLEEERTRFQELL 201
+RQ+ LE ER R QELL
Sbjct: 452 QELERQRRLEWERIRRQELL 471
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 34.3 bits (77), Expect = 0.092
Identities = 47/200 (23%), Positives = 77/200 (38%), Gaps = 43/200 (21%)
Query: 11 VHQAAVRPKGEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFARTKIDPSALVQKLEL- 69
+H + G+ P PP PP+ GK IN + + K+ +KL +
Sbjct: 306 MHLTDMAKAGQPLPLTLPPE---LVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLPVT 362
Query: 70 -DVRSVTSVRRGEAGSSARS---VPSIRRGAEAKTVLPKKE----KMKLRREQWLQKIEA 121
+ + + RG R + +R AE K K+E + +L+ ++W +++E
Sbjct: 363 FEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLEL 422
Query: 122 IKLAEQKHREERRRRATVVVGDLHPLRDALPELLGLEAGSRRQARSRESNKPRPSELSRM 181
K E++ ER+R E R+ RE+ K
Sbjct: 423 EKRLEKQRELERQR----------------------EEERRKDIERREAAK--------- 451
Query: 182 SAAQRQQLLEEERTRFQELL 201
+RQ+ LE ER R QELL
Sbjct: 452 QELERQRRLEWERIRRQELL 471
>gi|148612849 kinesin heavy chain member 2 isoform 2 [Homo sapiens]
Length = 744
Score = 34.3 bits (77), Expect = 0.092
Identities = 38/175 (21%), Positives = 74/175 (42%), Gaps = 8/175 (4%)
Query: 29 PAPEATPPPASAAGKDWAFINTNIFARTKIDPSALVQKLELDVRSVTSVRRGEAGSSARS 88
P+PE PPPAS+A + N A K DP + ++ R+ S + E SSA+
Sbjct: 74 PSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPS-QFPEQSSSAQQ 132
Query: 89 VPSIRRGAEAKTVLPKKEKMKLRREQWLQKIEAIKLAEQKHR---EERRRRATVVVGDLH 145
S+ + + + R+ ++++E ++ +K R +E R + V +
Sbjct: 133 NGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATN 192
Query: 146 PLRDALPELLGLEAGSRRQARSRESNKPRPSELSRMSAAQRQQLLEEERTRFQEL 200
P E++ + R R P + R+ R++ L ++ T+ ++L
Sbjct: 193 PNY----EIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDL 243
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,318,016
Number of Sequences: 37866
Number of extensions: 454492
Number of successful extensions: 7640
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 266
Number of HSP's that attempted gapping in prelim test: 6610
Number of HSP's gapped (non-prelim): 1144
length of query: 230
length of database: 18,247,518
effective HSP length: 99
effective length of query: 131
effective length of database: 14,498,784
effective search space: 1899340704
effective search space used: 1899340704
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.