Guide to the Human Genome
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Name: MAP3K1 Sequence: fasta or formatted (1512aa) NCBI GI: 153945765
Description:

mitogen-activated protein kinase kinase kinase 1

Referenced in:

MAP Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.4        127           4
 C cysteine            2.4         36           2
 D aspartate           3.8         57           2
 E glutamate           6.9        104           4
 F phenylalanine       2.6         39           1
 G glycine             6.5         98           5
 H histidine           2.5         38           3
 I isoleucine          4.0         60           4
 K lysine              4.5         68           2
 L leucine             9.0        136           3
 M methionine          2.4         36           2
 N asparagine          3.8         57           2
 P proline             7.0        106           3
 Q glutamine           4.5         68           3
 R arginine            6.4         97           3
 S serine             12.0        181           4
 T threonine           5.4         82           8
 V valine              5.6         84           3
 W tryptophan          0.9         14           1
 Y tyrosine            1.6         24           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mitogen-activated protein kinase kinase kinase 1 [H... 
MAP3K3                0.060   mitogen-activated protein kinase kinase kinase 3 iso...
MAP3K3                0.060   mitogen-activated protein kinase kinase kinase 3 iso...
MAP3K2                0.058   mitogen-activated protein kinase kinase kinase 2 [Ho...
YSK4                  0.053   Yeast Sps1/Ste20-related kinase 4 isoform 2 
YSK4                  0.052   Yeast Sps1/Ste20-related kinase 4 isoform 1 
MAP3K15               0.048   mitogen-activated protein kinase kinase kinase 15 [...
MAP3K5                0.046   mitogen-activated protein kinase kinase kinase 5 [Hom...
MAP3K4                0.046   mitogen-activated protein kinase kinase kinase 4 iso...
MAP3K4                0.046   mitogen-activated protein kinase kinase kinase 4 iso...
MAP3K6                0.043   mitogen-activated protein kinase kinase kinase 6 [Ho...
AURKA                 0.040   serine/threonine protein kinase 6 
AURKA                 0.040   serine/threonine protein kinase 6 
AURKA                 0.040   serine/threonine protein kinase 6 
AURKA                 0.040   serine/threonine protein kinase 6 
AURKA                 0.040   serine/threonine protein kinase 6 
AURKA                 0.040   serine/threonine protein kinase 6 
STK25                 0.038   serine/threonine kinase 25 
PLK3                  0.038   polo-like kinase 3 
STK24                 0.037   serine/threonine kinase 24 isoform a 
PAK2                  0.037   p21-activated kinase 2 
STK24                 0.037   serine/threonine kinase 24 isoform b 
PAK3                  0.037   p21-activated kinase 3 isoform d 
PAK3                  0.037   p21-activated kinase 3 isoform c 
PAK3                  0.037   p21-activated kinase 3 isoform b 
PAK3                  0.037   p21-activated kinase 3 isoform a 
PAK3                  0.037   p21-activated kinase 3 isoform a 
PAK3                  0.037   p21-activated kinase 3 isoform a 
SLK                   0.037   serine/threonine kinase 2 
NEK8                  0.036   NIMA-related kinase 8 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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