Guide to the Human Genome
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Search of human proteins with 171460958

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|171460958 nucleolar protein 10 [Homo sapiens]
         (688 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|171460958 nucleolar protein 10 [Homo sapiens]                     1377   0.0  
gi|148746195 trichohyalin [Homo sapiens]                               67   5e-11
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    65   2e-10
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    65   2e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    62   1e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    62   2e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    62   2e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    62   2e-09
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    61   3e-09
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    61   3e-09
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    61   3e-09
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    61   3e-09
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    61   3e-09
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]        60   7e-09
gi|221219020 NYD-SP11 protein [Homo sapiens]                           59   1e-08
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof...    59   1e-08
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof...    59   1e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    58   3e-08
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    58   3e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       57   6e-08
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    57   7e-08
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s...    56   1e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    55   2e-07
gi|115648142 centrosomal protein 164kDa [Homo sapiens]                 55   2e-07
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]            55   2e-07
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    55   2e-07
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    55   2e-07
gi|94721321 coiled-coil domain containing 11 [Homo sapiens]            54   4e-07
gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ...    54   5e-07
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            54   6e-07

>gi|171460958 nucleolar protein 10 [Homo sapiens]
          Length = 688

 Score = 1377 bits (3565), Expect = 0.0
 Identities = 688/688 (100%), Positives = 688/688 (100%)

Query: 1   MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKV 60
           MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKV
Sbjct: 1   MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKV 60

Query: 61  SKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIE 120
           SKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIE
Sbjct: 61  SKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIE 120

Query: 121 FHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENN 180
           FHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENN
Sbjct: 121 FHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENN 180

Query: 181 VCDINSVHGLFATGTIEGRVECWDPRTRNRVGLLDCALNSVTADSEINSLPTISALKFNG 240
           VCDINSVHGLFATGTIEGRVECWDPRTRNRVGLLDCALNSVTADSEINSLPTISALKFNG
Sbjct: 181 VCDINSVHGLFATGTIEGRVECWDPRTRNRVGLLDCALNSVTADSEINSLPTISALKFNG 240

Query: 241 ALTMAVGTTTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLDLILSADSRIVKMWNK 300
           ALTMAVGTTTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLDLILSADSRIVKMWNK
Sbjct: 241 ALTMAVGTTTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLDLILSADSRIVKMWNK 300

Query: 301 NSGKIFTSLEPEHDLNDVCLYPNSGMLLTANETPKMGIYYIPVLGPAPRWCSFLDNLTEE 360
           NSGKIFTSLEPEHDLNDVCLYPNSGMLLTANETPKMGIYYIPVLGPAPRWCSFLDNLTEE
Sbjct: 301 NSGKIFTSLEPEHDLNDVCLYPNSGMLLTANETPKMGIYYIPVLGPAPRWCSFLDNLTEE 360

Query: 361 LEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFA 420
           LEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFA
Sbjct: 361 LEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFA 420

Query: 421 YEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL 480
           YEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL
Sbjct: 421 YEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL 480

Query: 481 TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540
           TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG
Sbjct: 481 TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540

Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600
           KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE
Sbjct: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600

Query: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAE 660
           FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAE
Sbjct: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAE 660

Query: 661 KLHRQERKRLRRSAGHLKSRHKRGRSFH 688
           KLHRQERKRLRRSAGHLKSRHKRGRSFH
Sbjct: 661 KLHRQERKRLRRSAGHLKSRHKRGRSFH 688


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 59/288 (20%), Positives = 125/288 (43%), Gaps = 37/288 (12%)

Query: 422  EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
            ++ R  +  Q++ + R ++ + ++     +E   K  EEE++ ++   ++K       L 
Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR 1456

Query: 482  DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541
             +R +   E      + E ++            ++R +K    EQQ  R++ + +  E +
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLH---------RQERDRKFLEEEQQLRRQERDRKFREQE 1507

Query: 542  PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQER-----------LKEDQQTVLKP 590
                E      +E+  +   ++QR+ LQ+E++++RQER            +E++Q   + 
Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567

Query: 591  QFYEIKAGEEFRSFK---DSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTL 647
            +  ++   E  R F+       +Q+   K +ED  ++  + G   +       ++     
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL------RQERDRKF 1621

Query: 648  KRSEQQKKQQEAEKLHRQERKR--------LRRSAGHLKSRHKRGRSF 687
            +  EQ  +++E ++LHRQER R        LRR     + RH R R F
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 64/296 (21%), Positives = 137/296 (46%), Gaps = 44/296 (14%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
           EE+  ++  ++ E    +R   ++  +  +E   ++ +EEEEK+   W+K+      +L 
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE---WRKR----ETVLR 254

Query: 482 DDRFKVMFENPDFQ--VDEESEEFRLLN--PLVSKISEKRKKKLRLLEQQELREKEEEEE 537
            +  K+  E P  Q  + EE E+ R L    L  +  E+ +++ RL  +Q+LR K+EEE 
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314

Query: 538 PEGKPSDAESSESSDDE--------------------KAWVEEVRKQRRLLQQEEKVKRQ 577
            E +    E  E  + +                    +   EE R++++L +++E+ +R+
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374

Query: 578 ERLKEDQQTVLKPQF---YEIKAGEEFRSFKDSATKQKLMNK---TLEDRLKIEAKNGTL 631
           ++L+ +QQ   + Q     +++  ++ R  +    +Q+L  +     E +L+ E +    
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434

Query: 632 SVSDTTVGSKQLTFTLKRSEQQK----KQQEAEKLHRQERKRLRRSAGHLKSRHKR 683
                    +Q    LKR ++++    K++E  + H QER++ +      + R +R
Sbjct: 435 EQKHEQERREQ---RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 57/265 (21%), Positives = 130/265 (49%), Gaps = 30/265 (11%)

Query: 423  EYRKDKIRQKIEET-------RAQRVQLKKLPKVNKELALK----LIEEEEEKQKSTWKK 471
            +YRKDK  Q+ EE        + +R + +K  +  +EL  +    L EE E++++  W++
Sbjct: 959  QYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018

Query: 472  KVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELRE 531
            + +    +  ++   +  E    ++ E   ++R    L      +++++  L E++E R 
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEEL------QQEEEQLLGEERETRR 1072

Query: 532  KEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQ 591
            ++E E    K  + +  E    E+   EE  K+RR  ++E + + +E L+++++ +L+ +
Sbjct: 1073 RQELERQYRKEEELQQEE----EQLLREEPEKRRRQ-ERERQCREEEELQQEEEQLLREE 1127

Query: 592  FYEIKAGEEFRSFKD----SATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTL 647
              + +  E  R +++       +++L+ +  E R + E +       +     +QL    
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL--- 1184

Query: 648  KRSEQQKKQQEAEKLHRQERKRLRR 672
             R EQ+K++QE E+ +R+E +  R+
Sbjct: 1185 -REEQEKRRQERERQYREEEELQRQ 1208



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 66/282 (23%), Positives = 133/282 (47%), Gaps = 46/282 (16%)

Query: 422  EEYRKDKIRQKIEETRAQRVQ-LKKLPKVNKELALK---LIEEEEEKQKSTWKKKVKSLP 477
            E+ R  K R ++EE R +R   L   P + ++L  +   L EEEEE Q+   +K+ +   
Sbjct: 867  EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ-- 924

Query: 478  NILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLR---LLEQQELREKEE 534
                 ++ +   E    Q +EE         L+ +  EKR+++ R     + ++L++KEE
Sbjct: 925  -----EQERQYREEEQLQQEEEQ--------LLREEREKRRRQERERQYRKDKKLQQKEE 971

Query: 535  E---EEPEGKPSDA------ESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQ 585
            +   EEPE +          E  E   +E+  + E R++RR  + E + ++++ L+++++
Sbjct: 972  QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031

Query: 586  TVLKPQFYEIKAGEEFRSFKDSATKQK----LMNKTLEDRLKIEAKNGTLSVSDTTVGSK 641
             +L+ +  + +  E  R +++    Q+    L+ +  E R + E +       +      
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE------ 1085

Query: 642  QLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683
                 L++ E+Q  ++E EK  RQER+R  R    L+   ++
Sbjct: 1086 -----LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 61/267 (22%), Positives = 125/267 (46%), Gaps = 36/267 (13%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELA-----LKLIEEEEEKQKSTWKKKVKSL 476
           +E R+D ++++ E  R ++ + K+  K ++E       LKL EEE  +Q+   +++++  
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE 510

Query: 477 PNILTDDRFKVMFENP--------DFQVDEESEEFR--LLNPLVSKISEKRKKKLRLLEQ 526
                + R K   E          + Q+  E EE R  LL     K  E+ +++ RL  +
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570

Query: 527 QELREKE--EEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQ 584
           QE R  +  + EE   +       E   +++   EEV +  +  ++E+++KR+E  +E +
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERR 630

Query: 585 QTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLT 644
           Q +LK +  E +  ++ R  +    +Q+L  +  E+RL+   K                 
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR---------------- 674

Query: 645 FTLKRSEQQKKQQEAEKLHRQERKRLR 671
              +  E++++Q+ AE+   Q R+R++
Sbjct: 675 ---EHEEERREQELAEEEQEQARERIK 698



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 75/300 (25%), Positives = 137/300 (45%), Gaps = 55/300 (18%)

Query: 430  RQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTW-----------KKKVKSLPN 478
            RQ+ EE R +R    +L    +E A +  +EEE+++  TW           ++++ + P 
Sbjct: 732  RQEQEEKRRRRES--ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPP 789

Query: 479  ILTDDRFKVMFENPD-----FQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKE 533
            +      ++  E        F  +EE +E R       +   +R+K+L+ LE++E  ++ 
Sbjct: 790  LREQRERQLRAEERQQREQRFLPEEEEKEQR------RRQRREREKELQFLEEEEQLQRR 843

Query: 534  E-----EEEPEGKPSDAE---SSESSDDEK-AW-VEEVRKQRRLLQ------QEEKVKRQ 577
            E     +EE +G   D E   S E   D+K  W +EE RK+RR         QE+  K Q
Sbjct: 844  ERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903

Query: 578  ERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQK----LMNKTLEDRLKIEAKNGTLSV 633
            + L+E+++ + + +  + +  E+ R +++    Q+    L+ +  E R + E +      
Sbjct: 904  QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD 963

Query: 634  SDTTVGSKQLTFT----LKRSEQQKK-------QQEAEKLHRQERKRLRRSAGHLKSRHK 682
                   +QL        +R E++KK       QQE E+L R+ER++ RR     + R K
Sbjct: 964  KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 54/271 (19%), Positives = 125/271 (46%), Gaps = 30/271 (11%)

Query: 414  LMVNPFAYEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALK-----------LIEEEE 462
            L   P   E+ RK++   + EE   QR + +K  +  +E   +           L+ EE 
Sbjct: 889  LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREER 948

Query: 463  EKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLR 522
            EK++   +++       L     +++ E P+ +  +E E+             + +++L+
Sbjct: 949  EKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK-----------KYREEEELQ 997

Query: 523  LLEQQELRE-KEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLK 581
              E+Q LRE +E+    E +    +  E   +E+  + E R++RRL ++E + + +E L+
Sbjct: 998  QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057

Query: 582  EDQQTVLKPQFYEIKAGEEFRSFKD----SATKQKLMNKTLEDRLKIEAKNGTLSVSDTT 637
            ++++ +L  +    +  E  R ++        +++L+ +  E R + E +       +  
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117

Query: 638  VGSKQLTFTLKRSEQQKKQQEAEKLHRQERK 668
               +QL   L+   +++++QE E+ +R+E +
Sbjct: 1118 QEEEQL---LREEREKRRRQELERQYREEEE 1145



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 56/278 (20%), Positives = 133/278 (47%), Gaps = 33/278 (11%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
           EE R+ ++R++ EE R Q+++ ++  +  ++   +  EEE  +Q+   +++++    +  
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541
           + + +              ++ R    L  +   +R+++LR   +Q+LR ++EEE  E K
Sbjct: 392 EQQLR------------REQQLRREQQLRREQQLRREQQLR--REQQLRREQEEERHEQK 437

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGE-- 599
                  +    E+    +  K+    ++ E+ +R+++LK DQ+   + ++ +++  E  
Sbjct: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497

Query: 600 --------EFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSE 651
                   + R  ++   +Q+L  +  E+RL+   ++      +     +QL   LKR E
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL---LKREE 554

Query: 652 QQKKQQE--AEKLHRQERKR----LRRSAGHLKSRHKR 683
           +++ +QE   ++L R++ +R    L+R     + R KR
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 53/266 (19%), Positives = 126/266 (47%), Gaps = 23/266 (8%)

Query: 425  RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484
            R+++ +++ +E   Q  + KKL +  ++L   L EE E++++   +KK +    +  ++ 
Sbjct: 945  REEREKRRRQERERQYRKDKKLQQKEEQL---LGEEPEKRRRQEREKKYREEEELQQEEE 1001

Query: 485  FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEE-PEGKPS 543
              +  E    +  E   ++R            +K +L+  E+Q LRE+ E+    E +  
Sbjct: 1002 QLLREEREKRRRQEWERQYR------------KKDELQQEEEQLLREEREKRRLQERERQ 1049

Query: 544  DAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRS 603
              E  E   +E+  + E R+ RR  + E + +++E L+++++ +L+ +  + +  E  R 
Sbjct: 1050 YREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQ 1109

Query: 604  FKDSATKQK----LMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA 659
             ++    Q+    L+ +  E R + E +       +     +QL   L+   +++++QE 
Sbjct: 1110 CREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL---LREEPEKRRRQEL 1166

Query: 660  EKLHRQERKRLRRSAGHLKSRHKRGR 685
            E+ +R+E +  +     L+   ++ R
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRR 1192



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 57/291 (19%), Positives = 126/291 (43%), Gaps = 37/291 (12%)

Query: 423  EYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKS------L 476
            +YR+++  Q+ EE   +  Q K+  +  ++       EEEE Q+   K++ +       L
Sbjct: 1169 QYREEEELQQEEEQLLREEQEKRRQERERQY-----REEEELQRQKRKQRYRDEDQRSDL 1223

Query: 477  PNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE- 535
                  ++   + +N  +    E+E+FR L     +  + ++    LL +Q+ R++E+E 
Sbjct: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER 1283

Query: 536  ----------------EEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQER 579
                            E  E K +     +S ++++   EE  ++RR  + + K + +E+
Sbjct: 1284 RRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ 1343

Query: 580  LKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTL---EDRLKIEAKNGTLSVSDT 636
            L ++++         ++  E  R F++   + +   +     E RL+ + +       + 
Sbjct: 1344 LLQEREE------QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ 1397

Query: 637  TVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGRSF 687
             +  ++    L++   +K ++E ++L RQER R  R       R +R R F
Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF 1448



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 51/266 (19%), Positives = 126/266 (47%), Gaps = 21/266 (7%)

Query: 422  EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
            EE ++ + RQ+ E  +  +   ++     +E A +L EEE+  Q+   +++ +       
Sbjct: 814  EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR--- 870

Query: 482  DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE----LREKEEEEE 537
            D +++       +Q++EE +  R        + E+ +K+ +LL+++E      E+E+   
Sbjct: 871  DQKWR-------WQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923

Query: 538  PEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKA 597
             E +    E  +   +E+  + E R++RR  ++E + ++ ++L++ ++ +L  +  + + 
Sbjct: 924  QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983

Query: 598  GEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQ 657
             E  + +++    ++ + +  E  L+ E +       +     K     L++ E+Q  ++
Sbjct: 984  QEREKKYRE----EEELQQEEEQLLREEREKRRRQEWERQYRKKD---ELQQEEEQLLRE 1036

Query: 658  EAEKLHRQERKRLRRSAGHLKSRHKR 683
            E EK   QER+R  R    L+   ++
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQ 1062



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 61/266 (22%), Positives = 124/266 (46%), Gaps = 38/266 (14%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVN----KELALKLIEEEEEKQKSTWKKKVKSLP 477
           EE R+ +++++ EE   QR++ +++ ++     +E  LK  E EEE+++   K + +   
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642

Query: 478 NILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEE 537
                   +   E  + ++  E EE RL   L  +  E+R+       +QEL E+E+E+ 
Sbjct: 643 R--QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR-------EQELAEEEQEQA 693

Query: 538 PEGKPS-------DAESSESSDDEKAWVEEVRK--QRRLLQQEEKVKRQERLKEDQQTVL 588
            E   S         ES   +   K +    ++  QRR  +QEEK +R+E          
Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES--------- 744

Query: 589 KPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLK 648
                E++  EE R+ +    +++  + T + + + +++ G   +S      +Q    L+
Sbjct: 745 -----ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLR 799

Query: 649 RSEQQKKQQE--AEKLHRQERKRLRR 672
             E+Q+++Q    E+  +++R+R RR
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRR 825



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 53/263 (20%), Positives = 118/263 (44%), Gaps = 30/263 (11%)

Query: 419  FAYEEYRKDKIRQK-IEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLP 477
            F  +E R  +  +K +EE +    Q ++   + +E  L+  E  +++++   +K      
Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK------ 1556

Query: 478  NILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRK-----KKLRLLE-QQELRE 531
                +++ +   E       E   +FRL    V +  ++RK     ++LR  E QQ+LR+
Sbjct: 1557 -FREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ 1615

Query: 532  KE-----EEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQT 586
            +      E+E+   +  + +      D K   EE + +R+  +Q+ +  R  + +E++Q 
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL 1675

Query: 587  VLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFT 646
            + + +  +++  E  R F++            E +L+ + +       +  +  ++L   
Sbjct: 1676 LQEGEEQQLRRQERDRKFREE-----------EQQLRRQERERKFLQEEQQLRRQELERK 1724

Query: 647  LKRSEQQKKQQEAEKLHRQERKR 669
             +  EQ +++ E E+L RQER R
Sbjct: 1725 FREEEQLRQETEQEQLRRQERYR 1747



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 60/274 (21%), Positives = 132/274 (48%), Gaps = 35/274 (12%)

Query: 422  EEYRKDKIRQ-KIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL 480
            ++ R D+ R+ + EE   Q  + ++L +  ++   K  EEE++ ++   ++K       L
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDR--KFREEEQQLRRQERERKFLQEEQQL 1716

Query: 481  TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540
                 +  F   + Q+ +E+E+ +L          ++++  ++LE+++LR + EE++   
Sbjct: 1717 RRQELERKFREEE-QLRQETEQEQL---------RRQERYRKILEEEQLRPEREEQQLRR 1766

Query: 541  KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED-QQTVLKPQFYEIKAGE 599
            +  D +  E   +E+   E   +Q R  + + K + +E+L+++ ++  L+PQ        
Sbjct: 1767 QERDRKFRE---EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQ-------- 1815

Query: 600  EFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSD--TTVGSKQLTFTLKRSEQQKKQQ 657
              R  K    +++L  +  E RL+ E      +     T   S++    L + E+QK++Q
Sbjct: 1816 -QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ 1874

Query: 658  EAEK------LHRQERKRLR-RSAGHLKSRHKRG 684
            E E+      + RQ+++  R R  G +KS+  +G
Sbjct: 1875 ERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKG 1908



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 61/283 (21%), Positives = 121/283 (42%), Gaps = 31/283 (10%)

Query: 435  ETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTD-DRFKVMFENPD 493
            E   Q+   ++  K  +E  L   E EE++++    +K +    +L + +   +  +  D
Sbjct: 1300 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359

Query: 494  FQVDEES----EEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE-----------EP 538
             +  EE     E+ R       ++  + +++  L E+Q+LR +E E+           E 
Sbjct: 1360 RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREE 1419

Query: 539  EGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQER---LKEDQQTVLKPQFYEI 595
            E + S  E      +E+  V    ++R+ L++E++  RQER    +E++Q + + +  ++
Sbjct: 1420 EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ-LRQERHRKFREEEQLLQEREEQQL 1478

Query: 596  KAGEEFRSF---KDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQ 652
               E  R F   +    +Q+   K  E  L+ +         +  +  +Q      + EQ
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQ 1538

Query: 653  QKKQQEAEKLHRQERKRLRRSAGHLK--------SRHKRGRSF 687
            Q ++QE  +  RQ+R R  R    L+        SR +R R F
Sbjct: 1539 QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF 1581



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 54/269 (20%), Positives = 123/269 (45%), Gaps = 39/269 (14%)

Query: 422  EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
            E+  +++  Q++      R  L++ P++ ++       E E++ +    +K +    +L 
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQ-------EREQQLRHDRDRKFREEEQLLQ 1677

Query: 482  DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRK--KKLRLLEQQELREKEEEEEPE 539
            +       E    +  E   +FR     + +   +RK  ++ + L +QEL  K  EEE  
Sbjct: 1678 EG------EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731

Query: 540  GKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQER---LKEDQQTVLKPQFYEIK 596
             + ++ E     +  +  +EE  +Q R  ++E++++RQER    +E++Q   + +  +++
Sbjct: 1732 RQETEQEQLRRQERYRKILEE--EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLR 1789

Query: 597  AGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQ 656
            + E  R F++   +++L  +  E +L+ + ++G                  +  E+Q + 
Sbjct: 1790 SQESDRKFRE---EEQLRQEREEQQLRPQQRDGKY----------------RWEEEQLQL 1830

Query: 657  QEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
            +E E+  RQER R  R+     ++ K  R
Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRR 1859



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 62/284 (21%), Positives = 127/284 (44%), Gaps = 46/284 (16%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484
           R+ ++R++ EE R ++    K  +  +E  LK     E++++  W K+ +       + R
Sbjct: 421 REQQLRREQEEERHEQ----KHEQERREQRLK----REQEERRDWLKREEETERHEQERR 472

Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELRE----KEEEEE--- 537
            + +  +   Q +E  E +  L     +  ++R+++    EQ+E RE    ++EEEE   
Sbjct: 473 KQQLKRD---QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529

Query: 538 ---------PEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEK---------VKRQER 579
                       +    E     ++EK   +E R+QR   +QEE+          +RQ+R
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589

Query: 580 LKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVG 639
           LK +Q+  L+ +   +K  E  R  ++   +Q+L  +  E+    E +   L   +    
Sbjct: 590 LKREQEERLEQR---LKREEVERLEQEERREQRLKREEPEE----ERRQQLLKSEEQEER 642

Query: 640 SKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683
            +Q    L+R +Q++++Q  ++   +ER   R    H + R ++
Sbjct: 643 RQQ---QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 57/282 (20%), Positives = 123/282 (43%), Gaps = 32/282 (11%)

Query: 422  EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
            E +RK +  +++ + R ++ QL +     +E   K +EEE++ ++    +K +       
Sbjct: 1458 ERHRKFREEEQLLQEREEQ-QLHR-----QERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511

Query: 482  DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541
            +   K + E       +   +F     L  +   +R+++ +   Q   R+  EEE+   +
Sbjct: 1512 EPERKFLEEEQQLHRQQRQRKF-----LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566

Query: 542  PSDAESSESSDDEKAWVEE--VRKQ---RRLLQQEEKVKRQE-----------RLKEDQQ 585
              + + S    D K  +EE  VR+Q   R+ ++ E++++RQE           + +ED+Q
Sbjct: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQ 1626

Query: 586  TVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLE-----DRLKIEAKNGTLSVSDTTVGS 640
             + + +  ++   E  R F +   + +   +  +     DR   E +       +  +  
Sbjct: 1627 LLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRR 1686

Query: 641  KQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHK 682
            ++     +  EQQ ++QE E+   QE ++LRR     K R +
Sbjct: 1687 QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 61/280 (21%), Positives = 129/280 (46%), Gaps = 28/280 (10%)

Query: 425  RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484
            R+++ R+ +EE   Q+++ ++  K  +E   +L++E EE+Q    ++  K L     + +
Sbjct: 1441 RQERERKFLEEE--QQLRQERHRKFREEE--QLLQEREEQQLHRQERDRKFLEE---EQQ 1493

Query: 485  FKVMFENPDFQVDE---ESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKE---EEEEP 538
             +    +  F+  E   +  E + L        ++R++K  L E+Q+LR +E   +  + 
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF-LQEEQQLRRQERGQQRRQD 1552

Query: 539  EGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQE---RLKEDQQTVLKPQFYEI 595
              +    E     + E+  +    + R+   +E+KV+RQE   +  ED+Q + + +  + 
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612

Query: 596  KAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLK------- 648
               E  R F++    ++L+ +  E +L  + ++      +  +  ++    L+       
Sbjct: 1613 LRQERDRKFRED---EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669

Query: 649  RSEQQKKQQ-EAEKLHRQERKRLRRSAGHLKSRHKRGRSF 687
            R E+Q  Q+ E ++L RQER R  R       R +R R F
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 59/276 (21%), Positives = 134/276 (48%), Gaps = 21/276 (7%)

Query: 424  YRKDKIRQKIEETRAQRVQLKKLPKVNKELAL-----KLIEEEEEKQKSTWKKK-VKSLP 477
            +R+++ R+ +EE +  R Q +      +EL       K +EEE++  +   ++K ++   
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQ 1538

Query: 478  NILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE- 536
             +   +R +   ++ D +  EE E+ R          ++R +K RL EQ+  R+++E + 
Sbjct: 1539 QLRRQERGQQRRQDRDRKFREE-EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKF 1597

Query: 537  -EPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQ--EEKVKRQER----LKEDQQTVLK 589
             E E +    E  +    E+    + R+  +LLQ+  E+++ RQER    L+E+ Q   +
Sbjct: 1598 MEDEQQLRRQEGQQQLRQERD--RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655

Query: 590  PQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKR 649
             +  +++   + R F++   +++L+ +  E +L+ + ++      +  +  ++      +
Sbjct: 1656 EREQQLRHDRD-RKFRE---EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711

Query: 650  SEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
             EQQ ++QE E+  R+E +  + +      R +R R
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR 1747



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 62/268 (23%), Positives = 123/268 (45%), Gaps = 34/268 (12%)

Query: 423  EYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTD 482
            +YRK++  Q+ EE +  R + +K  +  +E   +  EEEE +Q+            +L +
Sbjct: 1079 QYRKEEELQQ-EEEQLLREEPEKRRRQERERQCR--EEEELQQEEE---------QLLRE 1126

Query: 483  DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542
            +R K   +  + Q  EE E  +    L+ +  EKR+++    + +E  E ++EEE   + 
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186

Query: 543  SDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLK-----EDQQTVLKPQFY-EIK 596
               +  +  + +    EE+++Q+R  +  ++ +R + LK     E +  V   + Y + +
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD-LKWQWEPEKENAVRDNKVYCKGR 1245

Query: 597  AGEEFRSFKDSATKQKLMNKTLEDRL------KIEAKNGTLSVSDTTVGSKQLTFTLKRS 650
              E+FR  +DS  + +   + L+  L        E +       D     ++    L+R 
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE---QLERE 1302

Query: 651  EQQ------KKQQEAEKLHRQERKRLRR 672
            EQ+      +K QE ++L R+ER+  RR
Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRR 1330



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 40/191 (20%), Positives = 89/191 (46%), Gaps = 8/191 (4%)

Query: 499 ESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSD-DEKAW 557
           + E+ R   P   ++ E+  ++ R   Q++ RE  E EE   K    E  +    DE+ W
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELW 174

Query: 558 VEEVRKQRRLLQQEEKVKRQERLK--EDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMN 615
               R+++   ++EE+   +E+L+  +  +T   P   +++  E     +    +++   
Sbjct: 175 ----RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230

Query: 616 KTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK-QQEAEKLHRQERKRLRRSA 674
           +  +DR+  E +       +T +  ++     +  ++Q++ Q+E E+L + ER+ LRR  
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290

Query: 675 GHLKSRHKRGR 685
              + + +R R
Sbjct: 291 QEEEQQQQRLR 301



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 43/216 (19%), Positives = 104/216 (48%), Gaps = 13/216 (6%)

Query: 459 EEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRK 518
           +EE++++     ++++  P      R +   +  + ++ E  E+      L  +  ++R 
Sbjct: 115 QEEDQRRFEPRDRQLEEEPG----QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD 170

Query: 519 KKL--RLLEQQELREKEEEEEPEGKPSDAESSESSDDE---KAWVEEVRKQRRLLQQEEK 573
           ++L  +  E QE  E+  EEE        E+ E  D+E   +  + E+R++ R  +Q+++
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230

Query: 574 VKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSV 633
            +RQ+R+ ++++     +   +   EE +  ++   +Q+ + +  E   K+E +     +
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ----EL 286

Query: 634 SDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKR 669
                  +Q    L+R +Q +++QE E+  +QE +R
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 66/275 (24%), Positives = 128/275 (46%), Gaps = 52/275 (18%)

Query: 425 RKDKIRQKIEETRAQ-----------RVQLKKLPKVNKEL---ALKLIEEEEEKQKSTWK 470
           +++KIR++ E+ R Q           R Q +K+ +  +E+     K+ E+EE++Q+  W+
Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410

Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEK---RKKKLRLLEQQ 527
           ++ K                  D ++ E+ EE       + ++ E    +++KLR +E++
Sbjct: 411 QEKK--------------MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456

Query: 528 ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV-------KRQERL 580
              E+E+ +E E K    E      +EK W     +Q +LL+QEEK+        RQE  
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTW-----RQEKLLKQEEKIWEQEEKMWRQEEK 511

Query: 581 KEDQQTVLKPQFYEIKAGEE--------FRSFKDSATKQKLMNKTLEDRL-KIEAKNGTL 631
             +Q+  ++ Q  +++  EE            ++   +Q++  + LE+RL K+  K   L
Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL 571

Query: 632 SVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQE 666
             +    GS++L       + + K QEA+ L +Q+
Sbjct: 572 GGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 46/242 (19%), Positives = 114/242 (47%), Gaps = 13/242 (5%)

Query: 439 QRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDF---- 494
           Q V  K   +V +     L+ +++E++    ++K++     + +   K+  +        
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331

Query: 495 -QVDEESEEFRLLNPLVSKISEK---RKKKLRLLEQQELREKEEEEEPEGKPSDAESSES 550
            ++ E+ E+ R     + +  EK   +++K+R  E++  R++E+  E + K  + E    
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMW 391

Query: 551 SDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATK 610
             +EK   +E ++Q ++ +QE+K++ Q+    +Q+  +  Q  +I+  EE    ++   +
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451

Query: 611 QKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRL 670
           + +  K  E+  K++ +   +   +  +  ++     K   Q+K  ++ EK+  QE K  
Sbjct: 452 E-VEEKMQEEEEKMQEQEEKIQRQEEKIQEQE----EKTWRQEKLLKQEEKIWEQEEKMW 506

Query: 671 RR 672
           R+
Sbjct: 507 RQ 508



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 48/251 (19%), Positives = 115/251 (45%), Gaps = 27/251 (10%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE---EKQKSTWKKKVKSLPNILT 481
           +++KI+++ E+   Q +++++  +       K+ E+EE   E++   W+++ K       
Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK------- 354

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541
                      + ++ E+ E+       + +  EK +++   + +QE + +E+EE+ + K
Sbjct: 355 -------IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601
               E      DEK   +E      + +QEEK++  E + +DQ+  L+    E K  EE 
Sbjct: 408 MWRQEKKMREQDEKIREQE----EEMWRQEEKIRELEEMMQDQEEKLRE--VEEKMQEEE 461

Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRS----EQQKKQQ 657
              ++   K +   + ++++ +   +   L   +  +  ++     +      +++K Q+
Sbjct: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521

Query: 658 EAEKLHRQERK 668
           + EK+ RQE K
Sbjct: 522 QEEKMQRQEEK 532



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 55/253 (21%), Positives = 112/253 (44%), Gaps = 21/253 (8%)

Query: 429 IRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKSLPNILTDD 483
           I +  +E  A  ++L +    ++EL  K  E +E     E +KS  +  VK L   L   
Sbjct: 192 IEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251

Query: 484 RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE---LREKEEEEEPEG 540
           +  +  +    + D   +E + ++  +    E+ +    L +QQE    R++E+ +E E 
Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311

Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600
           K  + E      +EK W    R++ ++ +QEEK+      +E +  + + +    +  E+
Sbjct: 312 KMCEQELKIREQEEKMW----RQEEKMHEQEEKI------REQEDKMWRQEEKIREQEEK 361

Query: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA- 659
            R  ++   +Q+   K  E   KI+ +   +   +  +  ++     K   Q+KK +E  
Sbjct: 362 IREQEEKMWRQE--EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD 419

Query: 660 EKLHRQERKRLRR 672
           EK+  QE +  R+
Sbjct: 420 EKIREQEEEMWRQ 432



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 52/283 (18%), Positives = 126/283 (44%), Gaps = 39/283 (13%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLP------KVNKELALKLIEEEEEKQKSTWKKKVKS 475
           + + +D   ++ E+++  +  LK++       +  ++  +  +++  ++ KS++KK+ + 
Sbjct: 82  KRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEK 141

Query: 476 LPNILTDDRFKVMFENPDFQVDEESEEFRLLNPL----------------VSKISEKRKK 519
           +       R +V+ + P  ++ E + + R  N L                + K++++R  
Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDA 201

Query: 520 -KLRL----LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV 574
             L L    +  +EL+EK  E + + +  ++E SE   + K    ++ + + LL Q++  
Sbjct: 202 PSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQ 261

Query: 575 KRQERLKEDQQTV---LKPQFYE------IKAGEEFRSFKDSATKQKLMNKTLEDRLKIE 625
              +RL ++ Q+V   L+ Q  E      +   +E + ++     Q+   K  E  LKI 
Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR 321

Query: 626 AKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERK 668
            +   +   +  +  ++      R ++ K  ++ EK+  QE K
Sbjct: 322 EQEEKMWRQEEKMHEQEEKI---REQEDKMWRQEEKIREQEEK 361


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 66/275 (24%), Positives = 128/275 (46%), Gaps = 52/275 (18%)

Query: 425 RKDKIRQKIEETRAQ-----------RVQLKKLPKVNKEL---ALKLIEEEEEKQKSTWK 470
           +++KIR++ E+ R Q           R Q +K+ +  +E+     K+ E+EE++Q+  W+
Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410

Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEK---RKKKLRLLEQQ 527
           ++ K                  D ++ E+ EE       + ++ E    +++KLR +E++
Sbjct: 411 QEKK--------------MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456

Query: 528 ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV-------KRQERL 580
              E+E+ +E E K    E      +EK W     +Q +LL+QEEK+        RQE  
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTW-----RQEKLLKQEEKIWEQEEKMWRQEEK 511

Query: 581 KEDQQTVLKPQFYEIKAGEE--------FRSFKDSATKQKLMNKTLEDRL-KIEAKNGTL 631
             +Q+  ++ Q  +++  EE            ++   +Q++  + LE+RL K+  K   L
Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL 571

Query: 632 SVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQE 666
             +    GS++L       + + K QEA+ L +Q+
Sbjct: 572 GGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 46/242 (19%), Positives = 114/242 (47%), Gaps = 13/242 (5%)

Query: 439 QRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDF---- 494
           Q V  K   +V +     L+ +++E++    ++K++     + +   K+  +        
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331

Query: 495 -QVDEESEEFRLLNPLVSKISEK---RKKKLRLLEQQELREKEEEEEPEGKPSDAESSES 550
            ++ E+ E+ R     + +  EK   +++K+R  E++  R++E+  E + K  + E    
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMW 391

Query: 551 SDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATK 610
             +EK   +E ++Q ++ +QE+K++ Q+    +Q+  +  Q  +I+  EE    ++   +
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451

Query: 611 QKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRL 670
           + +  K  E+  K++ +   +   +  +  ++     K   Q+K  ++ EK+  QE K  
Sbjct: 452 E-VEEKMQEEEEKMQEQEEKIQRQEEKIQEQE----EKTWRQEKLLKQEEKIWEQEEKMW 506

Query: 671 RR 672
           R+
Sbjct: 507 RQ 508



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 48/251 (19%), Positives = 115/251 (45%), Gaps = 27/251 (10%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE---EKQKSTWKKKVKSLPNILT 481
           +++KI+++ E+   Q +++++  +       K+ E+EE   E++   W+++ K       
Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK------- 354

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541
                      + ++ E+ E+       + +  EK +++   + +QE + +E+EE+ + K
Sbjct: 355 -------IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601
               E      DEK   +E      + +QEEK++  E + +DQ+  L+    E K  EE 
Sbjct: 408 MWRQEKKMREQDEKIREQE----EEMWRQEEKIRELEEMMQDQEEKLRE--VEEKMQEEE 461

Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRS----EQQKKQQ 657
              ++   K +   + ++++ +   +   L   +  +  ++     +      +++K Q+
Sbjct: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521

Query: 658 EAEKLHRQERK 668
           + EK+ RQE K
Sbjct: 522 QEEKMQRQEEK 532



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 55/253 (21%), Positives = 112/253 (44%), Gaps = 21/253 (8%)

Query: 429 IRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKSLPNILTDD 483
           I +  +E  A  ++L +    ++EL  K  E +E     E +KS  +  VK L   L   
Sbjct: 192 IEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251

Query: 484 RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE---LREKEEEEEPEG 540
           +  +  +    + D   +E + ++  +    E+ +    L +QQE    R++E+ +E E 
Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311

Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600
           K  + E      +EK W    R++ ++ +QEEK+      +E +  + + +    +  E+
Sbjct: 312 KMCEQELKIREQEEKMW----RQEEKMHEQEEKI------REQEDKMWRQEEKIREQEEK 361

Query: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA- 659
            R  ++   +Q+   K  E   KI+ +   +   +  +  ++     K   Q+KK +E  
Sbjct: 362 IREQEEKMWRQE--EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD 419

Query: 660 EKLHRQERKRLRR 672
           EK+  QE +  R+
Sbjct: 420 EKIREQEEEMWRQ 432



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 52/283 (18%), Positives = 126/283 (44%), Gaps = 39/283 (13%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLP------KVNKELALKLIEEEEEKQKSTWKKKVKS 475
           + + +D   ++ E+++  +  LK++       +  ++  +  +++  ++ KS++KK+ + 
Sbjct: 82  KRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEK 141

Query: 476 LPNILTDDRFKVMFENPDFQVDEESEEFRLLNPL----------------VSKISEKRKK 519
           +       R +V+ + P  ++ E + + R  N L                + K++++R  
Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDA 201

Query: 520 -KLRL----LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV 574
             L L    +  +EL+EK  E + + +  ++E SE   + K    ++ + + LL Q++  
Sbjct: 202 LSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQ 261

Query: 575 KRQERLKEDQQTV---LKPQFYE------IKAGEEFRSFKDSATKQKLMNKTLEDRLKIE 625
              +RL ++ Q+V   L+ Q  E      +   +E + ++     Q+   K  E  LKI 
Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR 321

Query: 626 AKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERK 668
            +   +   +  +  ++      R ++ K  ++ EK+  QE K
Sbjct: 322 EQEEKMWRQEEKMHEQEEKI---REQEDKMWRQEEKIREQEEK 361


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 44/247 (17%), Positives = 121/247 (48%), Gaps = 33/247 (13%)

Query: 424 YRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDD 483
           +R++K+R++ ++   Q  +++   +   +   ++ ++ +E++K TW ++ K        +
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRE 593

Query: 484 RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPS 543
           R K M E  +   ++E +             +++++K++  E++   ++E+ +E E K  
Sbjct: 594 REKKMREEEEMMREQEEK------------MQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641

Query: 544 DAESSESSDDEKAWVEE-VRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGE-EF 601
           + E      +EK W ++ + +Q+  L + EK++ QE+++E ++ + + +  E K  E E 
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701

Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661
           +++     +++   +  E +++ E +                   + R +++K Q++ EK
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEE-------------------MMREQEEKMQEQEEK 742

Query: 662 LHRQERK 668
           +  QE +
Sbjct: 743 MQEQEEE 749



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 68/272 (25%), Positives = 125/272 (45%), Gaps = 38/272 (13%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQK-----STWKKKVKS- 475
           EE  K++    +E  R   +  ++L K N EL  KL   E EK +        K+K++  
Sbjct: 200 EELTKERDALSLELYR-NTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERA 258

Query: 476 ---LPNILTDDRFKVMFENPDFQVDEESEEFRL-----------LNPLVSKISEKRKK-- 519
              LP + T+   + M+   + ++ E+ ++ R            L     K+ E+ +K  
Sbjct: 259 KFLLPQVQTNTLQEEMWRQEE-ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMW 317

Query: 520 --KLRLLEQQ-ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKR 576
             + RL EQ+ ELRE+E+E   + +  + E      +EK W +E     ++ +QEEK+ R
Sbjct: 318 RQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE----EKMREQEEKMWR 373

Query: 577 QERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDT 636
           QE    +Q+  ++ Q  +++  EE    +D   ++K      E+R++ + K     V   
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK------EERMREQEKMWE-QVEKM 426

Query: 637 TVGSKQLTFTLKRSEQQKKQQEAEKLHRQERK 668
               K      K  +Q++K QE E++  +E+K
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKK 458



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 59/265 (22%), Positives = 121/265 (45%), Gaps = 37/265 (13%)

Query: 423 EYRKDKIRQKIEETRAQRVQLK-KLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
           E  K +I+  ++E + +  + K  LP+V      + +  +EE+ +   KK  K    +  
Sbjct: 238 ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 297

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE-EEPEG 540
            +  + + E      ++E + +R    L  +  E R+++  L EQ+ELRE+EE+ +E E 
Sbjct: 298 QE--ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEE 355

Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600
           K  + E      +EK W    R++ RL +QE++++ QE+   DQ+  +  Q       E 
Sbjct: 356 KMWEQEEKMREQEEKMW----RQEERLWEQEKQMREQEQKMRDQEERMWEQ------DER 405

Query: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAE 660
            R  ++   +Q+ M + +E +++ E                      K+ ++Q+K+   +
Sbjct: 406 LREKEERMREQEKMWEQVE-KMREE----------------------KKMQEQEKKTRDQ 442

Query: 661 KLHRQERKRLRRSAGHLKSRHKRGR 685
           +   QE +R+R     ++   +  R
Sbjct: 443 EEKMQEEERIREREKKMREEEETMR 467



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 60/265 (22%), Positives = 122/265 (46%), Gaps = 30/265 (11%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKEL-ALKLIEEEEEK----------QKSTWK 470
           +E +  K  + + E   +  Q ++LP+  ++L   + ++E+EEK          Q+  W 
Sbjct: 469 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG 528

Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELR 530
           ++ K        ++   M+E  +   D+E + +     +  K  E+ KK     +++++R
Sbjct: 529 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD--QEEKMR 586

Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQR---RLLQQEEKVKRQERLKEDQQTV 587
           E+E   E E K  + E      +EK   +E + Q    ++ +QEEK++ QE    +Q+  
Sbjct: 587 EEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEK 646

Query: 588 LKPQFYEIKAGEEFRSFKDSATKQKLM-NKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFT 646
           +  Q  E K  E+ R  +    K+KL  ++ ++++ K++ +   +         +Q    
Sbjct: 647 MWEQ--EEKMWEQQRLPEQ---KEKLWEHEKMQEQEKMQEQEEKIW--------EQEKME 693

Query: 647 LKRSEQQKKQQEAEKLHRQERKRLR 671
            K  EQ+KK  + EK+  +E  R R
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMRER 718



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 51/250 (20%), Positives = 125/250 (50%), Gaps = 15/250 (6%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484
           ++ ++R++ +E R Q  +L++  ++ ++      E+ +E+++  W+++ K         R
Sbjct: 319 QEKRLREQEKELREQEKELREQKELREQE-----EQMQEQEEKMWEQEEKMREQEEKMWR 373

Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEK-RKKKLRLLEQQELREKEEEEEPEGKPS 543
            +      + Q+ E+ ++ R     + +  E+ R+K+ R+ EQ+++ E+ E+   E K  
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQ 433

Query: 544 DAESSESSDDEKAWVEE-VRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFR 602
           + E      +EK   EE +R++ + +++EE+  R++  K  +Q   +   +E +  +E++
Sbjct: 434 EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ---EENMWE-QEEKEWQ 489

Query: 603 SFKDSATKQKL--MNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQ--QE 658
             +    K+KL    K  E   KI  +   +   +   G ++  +  ++  +Q+ Q  ++
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549

Query: 659 AEKLHRQERK 668
            EK+  QE+K
Sbjct: 550 EEKMRDQEQK 559



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 59/291 (20%), Positives = 138/291 (47%), Gaps = 32/291 (10%)

Query: 422 EEYRKDKIRQKIEE-TRAQRVQLKKLPKVNKELALKLIEEEE----------EKQKSTWK 470
           E+ R++K  Q+ E+ TR Q  ++++  ++ +E   K+ EEEE          +++++ W+
Sbjct: 424 EKMREEKKMQEQEKKTRDQEEKMQEEERI-REREKKMREEEETMREQEEKMQKQEENMWE 482

Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEES---EEFRLLNPLVSKISEK---RKKKLRLL 524
           ++ K        ++ + ++E    Q  EE    +E ++ +       EK   R++K+R  
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542

Query: 525 EQQELREKEEEEEPEGKPSDAES----SESSDDEKAWVEE--VRKQRRLLQQEEKVKRQE 578
           E Q   ++E+  + E K  D E          ++K W +E  +R++ R+ ++E+K++ +E
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 602

Query: 579 RLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTV 638
            +  +Q+  ++ Q  +++  EE + ++     Q+   K  E   K+  +   +       
Sbjct: 603 EMMREQEEKMQEQEEKMQEQEE-KMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661

Query: 639 GSKQLTFTL-------KRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHK 682
             K+  +         K  EQ++K  E EK+ ++ +++ +++    K R +
Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE 712



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 61/263 (23%), Positives = 118/263 (44%), Gaps = 52/263 (19%)

Query: 429 IRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKSLPNILTDD 483
           I +  +E  A  ++L +    N+EL  K  E +E     E +KS  +  VK L   L   
Sbjct: 199 IEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERA 258

Query: 484 RFKVMFENPDFQVDEESEE-FRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542
           +F +    P  Q +   EE +R    L      +++KK+R  E++  R++E   E EGK 
Sbjct: 259 KFLL----PQVQTNTLQEEMWRQEEEL-----REQEKKIRKQEEKMWRQEERLREQEGKM 309

Query: 543 SDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGE 599
            + E       EK W +E R   +++ L +QE++++ Q+ L+E ++ + + +    +  E
Sbjct: 310 REQE-------EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE 362

Query: 600 EFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA 659
           + R  ++   +Q       E+RL  + K                    +  EQ++K ++ 
Sbjct: 363 KMREQEEKMWRQ-------EERLWEQEK--------------------QMREQEQKMRDQ 395

Query: 660 EKLHRQERKRLRRSAGHLKSRHK 682
           E+   ++ +RLR     ++ + K
Sbjct: 396 EERMWEQDERLREKEERMREQEK 418



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 42/186 (22%), Positives = 89/186 (47%), Gaps = 15/186 (8%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEE---KQKSTWKKKVKSLPN 478
           EE  +++ ++  EE    R Q +K+    +E   K+ E+EEE   +++  W+++ K    
Sbjct: 712 EESMREREKKMREEEEMMREQEEKM----QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ 767

Query: 479 ILTDDRFKVMFENPDFQ----VDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEE 534
               ++ + ++E+   Q    + E+ E+ R     +    EK + +   +  QE +   +
Sbjct: 768 QRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQ 827

Query: 535 EEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYE 594
           EE+  G+    E      +EK W +E + + ++  QEEK++ QE     Q+  ++ Q  +
Sbjct: 828 EEKMWGQ----EEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883

Query: 595 IKAGEE 600
           ++  EE
Sbjct: 884 MRGQEE 889



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 50/252 (19%), Positives = 113/252 (44%), Gaps = 36/252 (14%)

Query: 423 EYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEE---EEKQKSTWKKKVKSLPNI 479
           E+ K + ++K++E   +  + +K+ K  +E   K  ++E   EE+     +KK++    +
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728

Query: 480 LTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPE 539
           + +   K+  +    Q  EE               E  +++ ++ EQ+E +  E++  PE
Sbjct: 729 MREQEEKMQEQEEKMQEQEE---------------EMWEQEEKMWEQEE-KMWEQQRLPE 772

Query: 540 GKPSDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIK 596
            K    E  +  + EK W +E +   ++ ++  QEEK++ QE     Q+  +  Q  ++ 
Sbjct: 773 QKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMW 832

Query: 597 AGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQ 656
             EE    K    ++K+  +  +   K++ +   +   +  +          R +++K +
Sbjct: 833 GQEE----KMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKM----------RGQEEKMR 878

Query: 657 QEAEKLHRQERK 668
           ++ EK+  QE K
Sbjct: 879 EQEEKMRGQEEK 890



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 54/261 (20%), Positives = 130/261 (49%), Gaps = 28/261 (10%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE---EKQKSTWKKKVKSLPNILT 481
           +++K+R++ E  R +  ++++  ++ +E   K+ E+EE   E+++  W+++ K       
Sbjct: 581 QEEKMREE-ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM------ 633

Query: 482 DDRFKVMFENPD--FQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPE 539
            ++ + M+E  +  ++ +E+  E + L     K+ E  K + +  + QE  EK  E+E  
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE-KMQEQEEKIWEQEKM 692

Query: 540 GKPSDAESSESSDDEKAWVEEVRKQR--RLLQQEEKVKRQERLKEDQQTVLKPQFYEIKA 597
            K +  +  ++ D EK   EE  ++R  ++ ++EE ++ QE   ++Q+  ++ Q  E+  
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE 752

Query: 598 GEE---------FRSFKDSATKQKLM-NKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTL 647
            EE         +   +    K+KL  ++ ++++ KI  +   +   +  +  ++     
Sbjct: 753 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE---EK 809

Query: 648 KRSEQQKKQQEAEKLHRQERK 668
            R +++K + + EK+  QE K
Sbjct: 810 MRGQEEKMRGQEEKMWGQEEK 830



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 33/167 (19%), Positives = 76/167 (45%), Gaps = 14/167 (8%)

Query: 524 LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQ-------EEKVKR 576
           +  +EL++K  E + +   +++E SE   + K    ++ + + LL Q       EE  ++
Sbjct: 218 ITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 277

Query: 577 QERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDT 636
           +E L+E ++ + K +    +  E  R  +    +Q+      E RL+ + K       + 
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEK-------EL 330

Query: 637 TVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683
               K+L    +  EQ+++ QE E+   ++ +++R     +  + +R
Sbjct: 331 REQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 377


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 61/273 (22%), Positives = 137/273 (50%), Gaps = 23/273 (8%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKK--KVKSLPNILTD 482
           R++KI+++ E+ R Q  ++++  ++  E   K+  +EE      W+K  K++ L   + +
Sbjct: 300 REEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE----MMWEKEEKIRELEEKMHE 355

Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKI---SEK-RKKKLRLLEQQELREKEEEE-- 536
              K+  +    Q +E+  E        +K+    EK R+++ ++ EQ+E+ +++EE+  
Sbjct: 356 QE-KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414

Query: 537 EPEGKPSDAESSESSDDEKA--WVEEVRKQ-RRLLQQEEKVKRQERLKEDQQTVLKPQFY 593
           E E K  + E      +EK     E++R+Q +++ +QEEK++ QE + ++Q+  +  Q  
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ-- 472

Query: 594 EIKAGEEFRSFKDSATKQKLMNKTL-EDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQ 652
           E K  E+    ++   K +   + + E   KI  +   +   +  +  ++     K  EQ
Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE----KMWEQ 528

Query: 653 QKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
           ++K  E E+  +++ +++RR    ++ +  R R
Sbjct: 529 EEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLR 561



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 59/304 (19%), Positives = 141/304 (46%), Gaps = 36/304 (11%)

Query: 407 RLYHKVKLMVNPFAYEEYRKDKIRQKIEETRA----QRVQL------KKLPKVNKELALK 456
           +L  K++L+ +  +  +    ++++K+E  +     Q++Q       K+L  V+ +L  +
Sbjct: 213 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 272

Query: 457 LIEEE------EEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLV 510
           + E E      +++++  W+++ K        +R + + E  + ++ E+ E+ R    ++
Sbjct: 273 VEENELWNRLNQQQEEKMWRQEEK------IQEREEKIQEQEE-KIREQEEKMRRQEEMM 325

Query: 511 SKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQ 570
            +  EK +++  ++ ++E + +E EE+   +    E  E   +E    E++R+Q +  +Q
Sbjct: 326 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE----EKIREQEKRQEQ 381

Query: 571 EEKVKRQERLKEDQQTVLKP-----QFYEIKAGE-EFRSFKDSATKQKLMNKTLEDRLKI 624
           E K+ RQE    +Q+  ++      Q  E K GE E + ++     Q+   K      KI
Sbjct: 382 EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI 441

Query: 625 EAKNGTLSVSDTTVGSKQLTF---TLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRH 681
             +   +   +  +  ++        K  EQ+ K  E E   +++ +++RR    ++ + 
Sbjct: 442 REQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501

Query: 682 KRGR 685
           K+ R
Sbjct: 502 KKIR 505



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 44/211 (20%), Positives = 110/211 (52%), Gaps = 21/211 (9%)

Query: 424 YRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDD 483
           + ++KIR++ EE R +  ++++  K  ++ A    +EE+ +++   ++K++    ++ + 
Sbjct: 354 HEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ---EEKIREQEEMMQEQ 409

Query: 484 RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE------- 536
             K+     + ++ E+ EE +     + +  EK +++ + + +QE + +E+EE       
Sbjct: 410 EEKM--GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 467

Query: 537 ---EPEGKPSDAESSESSDDEK--AWVEEVRKQ-RRLLQQEEKVKRQERLKEDQQTVLKP 590
              E EGK  + E+     +EK     E++R+Q +++ +QEEK++ QE + ++Q+  +  
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527

Query: 591 QFYEIKAGEEFRSFKDSATKQKLMNKTLEDR 621
           Q  E K  E+    ++   K +   + + ++
Sbjct: 528 Q--EEKMCEQEEKMQEQEEKMRRQEEKMREQ 556



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 51/264 (19%), Positives = 122/264 (46%), Gaps = 23/264 (8%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484
           +++ + +K E+ R Q   + +  +  +EL  K+ E+E+ +++   +++ + +        
Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 380

Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSD 544
            +      + ++ E+ E+ R    ++ +  EK       + +QE +  E+EEE +     
Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEEK-------MGEQEEKMWEQEEEMQ----- 428

Query: 545 AESSESSDDEKAWVEEVRKQ-RRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRS 603
               E  +  +   E++R+Q +++ +QEEK++ QE + ++Q+  +  Q  E K  E+   
Sbjct: 429 ----EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ--EGKMCEQEAK 482

Query: 604 FKDSATKQKLM-NKTLEDRLKIEAKNGTLSVSDTTV---GSKQLTFTLKRSEQQKKQQEA 659
            ++   K +    K  E   KI  +   +   +  +     K      K  EQ++K QE 
Sbjct: 483 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 542

Query: 660 EKLHRQERKRLRRSAGHLKSRHKR 683
           E+  R++ +++R     L+ + ++
Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEK 566



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 36/154 (23%), Positives = 81/154 (52%), Gaps = 11/154 (7%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484
           ++++++++ E+ R Q  ++++  K  +E   K+ E+EE  Q+   ++K+      + +  
Sbjct: 423 QEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ--EEKMGEQEGKMCEQE 480

Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE---EPEGK 541
            K+  +  + ++  + E+ R     + +  EK +++  ++++QE +  E+EE   E E K
Sbjct: 481 AKM--QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVK 575
             + E      +EK   +EV    RL QQEEK++
Sbjct: 539 MQEQEEKMRRQEEKMREQEV----RLRQQEEKMQ 568



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 34/165 (20%), Positives = 69/165 (41%), Gaps = 19/165 (11%)

Query: 524 LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED 583
           +  +EL+EK  + + + +  ++E SE   + K    ++ + + LL Q++     + L ++
Sbjct: 202 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 261

Query: 584 QQTV---LKPQFYE------IKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVS 634
            Q+V   L+ Q  E      +   +E + ++     Q+   K  E   KI  +   +   
Sbjct: 262 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321

Query: 635 DTTVGSKQLTFTL----------KRSEQQKKQQEAEKLHRQERKR 669
           +  +  K+               K  E ++K  E EK+  QE KR
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 366


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 57/273 (20%), Positives = 133/273 (48%), Gaps = 27/273 (9%)

Query: 425 RKDKIRQKIEETRAQRVQL-KKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDD 483
           +++KIR++ E+ R Q  ++ ++  K++++  ++  EE+ ++Q+  W+++ K         
Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE-EEKRQEQEEMWRQEEKIHEQEEIWR 493

Query: 484 RFKVMFENPDFQVDEESEEFRL---LNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540
           + + M E  +    +E + +R    +     KI E+ +K  R  +++++RE+EE    E 
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR--QEEKIREQEEMWREEE 551

Query: 541 KPSD-----AESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQERLKEDQQTVLKPQF 592
           K  +      E      ++K W +E +   ++ ++ +QEEK++ QE  +++Q+  +  Q 
Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611

Query: 593 YEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQ 652
            +I+  EE          Q+   K  E   KI  +       +  +G ++     K  EQ
Sbjct: 612 EKIREQEE--------KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE----EKMCEQ 659

Query: 653 QKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
           ++K QE E+   ++ +++R     ++ + ++ R
Sbjct: 660 EEKMQEQEETMWRQEEKIREQEKKIREQEEKIR 692



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 57/250 (22%), Positives = 123/250 (49%), Gaps = 17/250 (6%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKK--KVKSLPNILTD 482
           +++KIR++ E+ R Q  ++++  ++  E   K+  +EE      W+K  K++    ++ +
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE----MMWEKEEKMRRQEEMMWE 374

Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542
              K+     +  + E+ E+ R L   + +  + R+++ +  E++++RE+E+ +E E K 
Sbjct: 375 KEEKM--RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432

Query: 543 SDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED----QQTVLKPQFYEIKAG 598
              E      +EK   +E    +++ +QEEK+  QE+++E+    +Q  +  Q  +I   
Sbjct: 433 WRQEEKIREQEEKIREQE----KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ 488

Query: 599 EEFRSFKDSATKQKLMNKTLEDRL-KIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQ 657
           EE    K+   +Q+   +  E+++ + E K             K      K  EQ++  +
Sbjct: 489 EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWR 548

Query: 658 EAEKLHRQER 667
           E EK+H QE+
Sbjct: 549 EEEKMHEQEK 558



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 61/272 (22%), Positives = 131/272 (48%), Gaps = 28/272 (10%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEE---KQKSTWKK--KVKSL 476
           E+ R+++ RQ+ EE   Q  ++ +  ++ ++   K+ E+EE+   +++  W++  K++  
Sbjct: 464 EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE-KMHEQEEKIRKQEEKVWRQEEKIREQ 522

Query: 477 PNILTDDRFKVMFENPDFQVDEES--EEFRLLNPLVSKISEKRKKKLRLLEQQELREKEE 534
              + +   K+  +    +  EE   EE ++         EKR+++   + +QE + +E+
Sbjct: 523 EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582

Query: 535 EEE---PEGKPSDAESSESSDDEKAWVEE--VRKQRRLLQ-QEEKVKRQERLKEDQQTVL 588
           EE+    E K  + E      +EK W +E  +R+Q   +Q QEEK++ QE    +Q+ + 
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT 642

Query: 589 KPQFYEIKAGEEFRSFKDSATKQKLMNKTL--------EDRLKIEAKNGTLSVSDTTVGS 640
           + Q  E K GE+     +   K +   +T+        E   KI  +   +   +  +  
Sbjct: 643 QEQ--EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQE 700

Query: 641 KQLTFTLKRSEQQKKQQEAEKLHRQERKRLRR 672
           ++     K  EQ++K  E E+  +++ +++RR
Sbjct: 701 QEE----KMWEQEEKMCEQEEKMQEQEEKMRR 728



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 45/246 (18%), Positives = 123/246 (50%), Gaps = 30/246 (12%)

Query: 425 RKDKIRQKIEETRAQRVQL-KKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDD 483
           +++KIR++ E+ R Q  ++ ++  K+ ++  +   EE+  +Q+  W+++ +        +
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ-------E 567

Query: 484 RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPS 543
           +   M+   + ++ E+ E+       + +  EKR+++   + +QE + +E+EE+ + +  
Sbjct: 568 QEDKMWRQEE-KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE 626

Query: 544 DAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRS 603
                E    E+  + + ++++   Q+E+  +++E+++E ++T+ + +    +  ++ R 
Sbjct: 627 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686

Query: 604 FKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQE-AEKL 662
            ++   +Q+ M +  E+++  + +                    K  EQ++K QE  EK+
Sbjct: 687 QEEKIREQEEMMQEQEEKMWEQEE--------------------KMCEQEEKMQEQEEKM 726

Query: 663 HRQERK 668
            RQE K
Sbjct: 727 RRQEEK 732



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 39/166 (23%), Positives = 85/166 (51%), Gaps = 21/166 (12%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484
           +++KIR++ E+ + Q  ++ K  +  +E   K+ E+EE+ ++   ++K++    +  +  
Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ--EEKIREQEEMTQEQE 646

Query: 485 FKV------MFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE-- 536
            K+      M E  +   ++E   +R    +  +  + R+++ ++ EQ+E+ +++EE+  
Sbjct: 647 EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 706

Query: 537 -------EPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVK 575
                  E E K  + E      +EK W +EV    RL QQEEK++
Sbjct: 707 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV----RLRQQEEKMQ 748



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 39/179 (21%), Positives = 90/179 (50%), Gaps = 11/179 (6%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484
           +++KIR++ E+   Q  ++++  +  +E   K+ ++EE+ ++   ++K++     + +  
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ--EEKIQEQEEKIREQE 632

Query: 485 FKVMFENPDFQVDEES--EEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE-EEPEGK 541
            K+  +    Q  EE   E+   +     K+ E+ +   R  +++++RE+E++  E E K
Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR--QEEKIREQEKKIREQEEK 690

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600
             + E      +EK W +E     ++ +QEEK++ QE     Q+  +  Q   ++  EE
Sbjct: 691 IREQEEMMQEQEEKMWEQE----EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 60/275 (21%), Positives = 127/275 (46%), Gaps = 25/275 (9%)

Query: 425 RKDKIRQKIEETRAQR----VQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKS 475
           +K K  + IEE   +R    ++L +    ++EL  K  + +E     E +KS  +  VK 
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246

Query: 476 LPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE 535
           L   L   +  +  +    + D   +E + ++  +    E+ +   RL +QQE +   +E
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 306

Query: 536 E---EPEGKPSDAESSESSDDEKAWVEEVRKQRR---LLQQEEKVKRQERLK-EDQQTVL 588
           E   E E K  + E      +EK   +E + +R+   + ++EEK++RQE +  E ++ + 
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366

Query: 589 KPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLK 648
           + +    +  E+ R  ++   +++   + LE+++  + K             ++     K
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK--------IREQEEKRQEEEK 418

Query: 649 RSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683
             EQ+K+Q++  K+ RQE K +R     ++ + K+
Sbjct: 419 IREQEKRQEQEAKMWRQEEK-IREQEEKIREQEKK 452



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 38/194 (19%), Positives = 84/194 (43%), Gaps = 45/194 (23%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484
           ++DK+ ++ E+ R Q  ++ +  +  +E      E+ +E+++  WK++ K          
Sbjct: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQE----EKRQEQEEKMWKQEEK---------- 613

Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE-------- 536
                   + ++ E+ E+ R     + +  E  +++   + +QE +  E+EE        
Sbjct: 614 ----IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669

Query: 537 ----------------EPEGKPSDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQ 577
                           E E K  + E      +EK W +E +   ++ ++ +QEEK++RQ
Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729

Query: 578 ERLKEDQQTVLKPQ 591
           E    +Q+  L+ Q
Sbjct: 730 EEKMWEQEVRLRQQ 743



 Score = 30.0 bits (66), Expect = 7.5
 Identities = 47/225 (20%), Positives = 86/225 (38%), Gaps = 55/225 (24%)

Query: 462 EEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKL 521
           EE  K      ++   N +TD+  K   +N   Q     E+ +L+    S+I    K+  
Sbjct: 196 EELTKERDALSLELYRNTITDEELKE--KNAKLQ-----EKLQLVESEKSEIQLNVKELK 248

Query: 522 RLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRL-LQQEEKVKRQERL 580
           R LE+ +L   +++ + E      E    S   +A VEE     RL  QQEEK+ RQE  
Sbjct: 249 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK 308

Query: 581 KEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGS 640
            ++ +  ++ Q  +I+  EE                                        
Sbjct: 309 IQEWEEKIQEQEEKIREQEE---------------------------------------- 328

Query: 641 KQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
                  K  EQ++K +  E++  ++ +++RR    +  + ++ R
Sbjct: 329 -------KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 58/266 (21%), Positives = 130/266 (48%), Gaps = 10/266 (3%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
           EE   ++ +Q  E+ +  R Q +++ + ++ L  K  EE   +Q+  W+++ K       
Sbjct: 337 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREK--EERMREQEKMWEQEEKMQEEERI 394

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE-LREKEEEEEPEG 540
            +R K M E  +  + E+ E+ +     + +  EK  ++ RL EQ+E L E+E+ +E E 
Sbjct: 395 REREKKMREEEE-TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 453

Query: 541 KPSDAESSESSDDEKAWVEEVR--KQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAG 598
           K  + E  +  D E+ W +E +  +Q ++ +QE+++  QE    DQ+  +  Q  E +  
Sbjct: 454 KIWEQEE-KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ--EERMW 510

Query: 599 EEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKR-SEQQKKQQ 657
           E+    ++   + +   K  +   K+  +  T      T   ++     +R  E++KK +
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR 570

Query: 658 EAEKLHRQERKRLRRSAGHLKSRHKR 683
           E E++ R++ ++++     ++ + ++
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEK 596



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 52/277 (18%), Positives = 132/277 (47%), Gaps = 23/277 (8%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKEL-ALKLIEEEEEK----------QKSTWK 470
           +E +  K  + + E   +  Q ++LP+  ++L   + ++E+EEK          Q+  W 
Sbjct: 411 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG 470

Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELR 530
           ++ K        ++   M+E  +   D+E + +     +  +    R+K+ R+ EQ+++ 
Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530

Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKP 590
           ++EE+   E K  + E      +EK     +R++ R+ ++E+K++ +E +  +Q+  ++ 
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEK-----MREEERMREREKKMREEEEMMREQEEKMQE 585

Query: 591 QFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKI--EAKNGTLSVSDTTVGSKQLTFTLK 648
           Q  +++  EE + ++     Q+   K  E   K+  + +   +   +  +  ++     K
Sbjct: 586 QEEKMREQEE-KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE----EK 640

Query: 649 RSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
             EQ++K  E E+  R++ +++R     ++ + ++ R
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 677



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 66/271 (24%), Positives = 115/271 (42%), Gaps = 62/271 (22%)

Query: 429 IRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKSLPNILTDD 483
           I +  +E  A  ++L +    N+EL  K  E +E     E +KS  +  VK L   L   
Sbjct: 161 IEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERA 220

Query: 484 RF---KVMFENPDFQVDEESEEFRLLNPLVSKISEK----------------------RK 518
           +F   +V       ++  + EE R     + K  EK                      R+
Sbjct: 221 KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR 280

Query: 519 KKLRLLEQQ-ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQ 577
           ++ RL EQ+ ELRE+E+E   + K  + E      +EK W +E     ++ +QEEK+ RQ
Sbjct: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE----EKMREQEEKMWRQ 336

Query: 578 ERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTT 637
           E    +Q+  ++ Q  +++  EE    +D   ++K      E+R++ +            
Sbjct: 337 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREK------EERMREQE----------- 379

Query: 638 VGSKQLTFTLKRSEQQKKQQEAEKLHRQERK 668
                     K  EQ++K QE E++  +E+K
Sbjct: 380 ----------KMWEQEEKMQEEERIREREKK 400



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 42/185 (22%), Positives = 90/185 (48%), Gaps = 21/185 (11%)

Query: 427 DKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFK 486
           +++R+K E  R Q+   ++  K+ +E      ++ +E++K TW ++ K        +R K
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREE------KKTQEQEKKTWDQEEKMREEERMREREK 567

Query: 487 VMFENPDF------QVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540
            M E  +       ++ E+ E+ R     + +  EK +++   + +QE +  E+EEE + 
Sbjct: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627

Query: 541 KPS-----DAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEI 595
           +       + E      +EK W +E     ++ +QEEK++ QE   + Q+  ++ Q  ++
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQE----EKMREQEEKMREQEEKMQGQEEKMREQEEKM 683

Query: 596 KAGEE 600
           +  EE
Sbjct: 684 QGQEE 688



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 78/400 (19%), Positives = 176/400 (44%), Gaps = 42/400 (10%)

Query: 277 SVHFQDSLDLILSADSRIVKMWNKNSGKIFTSLEPEHDLNDVCLYPNSGMLLTANETPKM 336
           S HF   L   LSA    V  W+K + +    L  E D   + LY N+   +T  E  K 
Sbjct: 136 SWHFAGELQRALSA----VSTWHKKADRYIEELTKERDALSLELYRNT---ITNEELKKK 188

Query: 337 GIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLR 396
                  L                L E+ +S +  + K + +K      L   + +  L+
Sbjct: 189 NAELQEKL---------------RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 233

Query: 397 AYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALK 456
             M     ++R   K         + +  ++++R++  + R Q  ++++  K  +E   +
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQ--EERLREQEGKMREQEEKMRRQEKRLREQEKE 291

Query: 457 LIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEK 516
           L E+E+E ++   +KK++     + +   K M+E  +   ++E + +R    L  +  + 
Sbjct: 292 LREQEKELRE---QKKLREQEEQMQEQEEK-MWEQEEKMREQEEKMWRQEERLWEQEKQM 347

Query: 517 RKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEE--VRKQRRLLQQEEKV 574
           R+++ ++ +Q+E   +++E   E      +     + EK W +E  ++++ R+ ++E+K+
Sbjct: 348 REQEQKMRDQEERMWEQDERLRE------KEERMREQEKMWEQEEKMQEEERIREREKKM 401

Query: 575 KRQERLKEDQQTVLKPQFYEI--KAGEEFRSFKDSATKQKL--MNKTLEDRLKIEAKNGT 630
           + +E    +Q+  ++ Q   +  +  +E++  +    K+KL    K  E   KI  +   
Sbjct: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461

Query: 631 LSVSDTTVGSKQLTFTLKRSEQQKKQ--QEAEKLHRQERK 668
           +   +   G ++  +  ++  +Q+ Q  ++ EK+  QE+K
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 37/175 (21%), Positives = 89/175 (50%), Gaps = 10/175 (5%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484
           +++K++++ E+ R Q  ++ +  +  +E   K+ E+EE+  +   + K++    ++ +  
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638

Query: 485 FKV------MFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEP 538
            K+      M+E  + ++ E+ E+ R     +    EK +++   ++ QE + +E+EE+ 
Sbjct: 639 EKMQEQEEKMWEQEE-KMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKM 697

Query: 539 EGKPSDAESSESS---DDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKP 590
            G+       E      +EK W +E  +++    +++K K QERL E ++   +P
Sbjct: 698 RGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEP 752



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 55/258 (21%), Positives = 108/258 (41%), Gaps = 33/258 (12%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE---EKQKSTWKKKVKSLPNILT 481
           +++KIR + EE   Q  ++ +  K+ +E   ++ E+EE   ++++  W ++ +       
Sbjct: 458 QEEKIRDQ-EEMWGQEKKMWRQEKM-REQEDQMWEQEEKMRDQEQKMWDQEERMWEQ--- 512

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE----- 536
           D+R +   E    Q     +E ++     ++  EK+        ++E R +E E+     
Sbjct: 513 DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572

Query: 537 -----EPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQ 591
                E E K  + E      +EK W +E + Q    +QEEK+  QE    +Q+   K Q
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ----EQEEKMWEQEEKMWEQEEEDKMQ 628

Query: 592 FYEIKAGEEFRSFKDSATKQ-KLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRS 650
             E    E+    ++   K  +   K  E   K+  +   +   +  +          R 
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM----------RE 678

Query: 651 EQQKKQQEAEKLHRQERK 668
           +++K Q + EK+  QE K
Sbjct: 679 QEEKMQGQEEKMREQEEK 696



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 34/167 (20%), Positives = 78/167 (46%), Gaps = 14/167 (8%)

Query: 524 LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQ-------EEKVKR 576
           +  +EL++K  E + + + +++E SE   + K    ++ + + LL Q       EE  ++
Sbjct: 180 ITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 239

Query: 577 QERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDT 636
           +E L+E ++ + K +    +  E  R  +    +Q+   +  E RL+ + K       + 
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEK-------EL 292

Query: 637 TVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683
               K+L    K  EQ+++ QE E+   ++ +++R     +  + +R
Sbjct: 293 REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 60/250 (24%), Positives = 124/250 (49%), Gaps = 36/250 (14%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKK--KVKSLPNILTD 482
           +++KIR++ E+ R Q  ++++  ++  E   K+  +EE      W+K  K++ L  ++ +
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE----MMWEKEEKMRRLEEMMWE 374

Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542
              K+       +++E+  E         KI E+ +K+    E++++RE+E+ +E E K 
Sbjct: 375 KEEKIR------ELEEKMHE-------QEKIREQEEKRQ---EEEKIREQEKRQEQEAKM 418

Query: 543 SDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED----QQTVLKPQFYEIKAG 598
              E      +EK   +E    +++ +QEEK+  QE+++E+    +Q  +  Q  +I+  
Sbjct: 419 WRQEEKIREQEEKIREQE----KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 474

Query: 599 EEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQE 658
           EE    K+   +Q+ + K  E   + E K     + D     ++    + R E++ ++QE
Sbjct: 475 EEIWRQKEKMHEQEKIRKQEEKVWRQEEK-----MHDQEEKIREQEEKMWRQEEKIREQE 529

Query: 659 AEKLHRQERK 668
            EK+  QE K
Sbjct: 530 -EKIREQEEK 538



 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 59/249 (23%), Positives = 121/249 (48%), Gaps = 32/249 (12%)

Query: 425 RKDKIRQKIEETRAQRVQL-KKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDD 483
           +++KIR++ E+ R Q  ++ ++  K++++  ++  EE+ ++Q+  W+++ K         
Sbjct: 421 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE-EEKRQEQEEMWRQEEKIREQEEIWR 479

Query: 484 RFKVMFENPDFQVDEES--EEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE-EEPEG 540
           + + M E    +  EE    +   ++    KI E+ +K  R  +++++RE+EE+  E E 
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR--QEEKIREQEEKIREQEE 537

Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600
           K  + E      +EK     + +Q   +Q++EK++RQE    +Q+  ++ Q  +I+  EE
Sbjct: 538 KIREQEEMMQEQEEK-----MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592

Query: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQE-A 659
                          K  E   KI  +   +   +  +  ++     K  EQ++K QE  
Sbjct: 593 ---------------KIWEQEEKIREQEEMMQEQEEKMWEQE----EKMCEQEEKMQEQE 633

Query: 660 EKLHRQERK 668
           EK+ RQE K
Sbjct: 634 EKMRRQEEK 642



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 43/161 (26%), Positives = 86/161 (53%), Gaps = 20/161 (12%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484
           +++KIR++ E+ R Q  ++++  ++ +E   K+ E+EE+ Q+   ++K++     + +  
Sbjct: 521 QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE---QEKMRRQEEKIREQE 577

Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE---EPEGK 541
            K+          E+ E+ R     + +  EK +++  ++++QE +  E+EE   E E K
Sbjct: 578 EKIR---------EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV-KRQERLK 581
             + E      +EK W +EV    RL QQEEK+ + QE L+
Sbjct: 629 MQEQEEKMRRQEEKMWEQEV----RLRQQEEKMQEHQEHLE 665



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 52/284 (18%), Positives = 131/284 (46%), Gaps = 26/284 (9%)

Query: 407 RLYHKVKLMVNPFAYEEYRKDKIRQKIEETRA----QRVQL------KKLPKVNKELALK 456
           +L  K++L+ +  +  +    ++++K+E  +     Q++Q       K+L  V+ +L  +
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284

Query: 457 LIEEE------EEKQKSTWKK--KVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNP 508
           + E E      +++++  W++  K++     + +   K+     + ++ E+ E+ R    
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI--REQEEKIREQEEKMRRQEE 342

Query: 509 LVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLL 568
           ++ +  EK +++  ++ ++E + +  EE    K       E    E+   E++R+Q    
Sbjct: 343 MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ---EKIREQEEKR 399

Query: 569 QQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKN 628
           Q+EEK++ QE+ +E +  + +    E K  E+    ++   K     + + ++ KI  + 
Sbjct: 400 QEEEKIREQEKRQEQEAKMWRQ---EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 456

Query: 629 GTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRR 672
                 +     +++    +   Q++K  E EK+ +QE K  R+
Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ 500



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 45/197 (22%), Positives = 106/197 (53%), Gaps = 22/197 (11%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELAL------KLIEEEE---EKQKSTWKK--KV 473
           +++KIR++ EE   Q+ ++ +  K+ K+         K+ ++EE   E+++  W++  K+
Sbjct: 467 QEEKIREQ-EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525

Query: 474 KSLPNILTDDRFKV-----MFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE 528
           +     + +   K+     M +  + ++ E+ E+ +    +  +  + R+++ ++ EQ+E
Sbjct: 526 REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKE 585

Query: 529 -LREKEEEE-EPEGKPSDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQERLKED 583
            +RE+EE+  E E K  + E      +EK W +E +   ++ ++ +QEEK++RQE    +
Sbjct: 586 KIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 645

Query: 584 QQTVLKPQFYEIKAGEE 600
           Q+  L+ Q  +++  +E
Sbjct: 646 QEVRLRQQEEKMQEHQE 662



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 64/277 (23%), Positives = 125/277 (45%), Gaps = 43/277 (15%)

Query: 425 RKDKIRQKIEETRAQR----VQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKS 475
           +K K  + IEE   +R    ++L +    ++EL  K  + +E     E +KS  +  VK 
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246

Query: 476 LPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE 535
           L   L   +  +  +    + D   +E + ++  +    E+ +   RL +QQE +   +E
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 306

Query: 536 E---EPEGKPSDAESSESSDDEKAWVEEVRKQRR---LLQQEEKVKRQERL---KEDQQT 586
           E   E E K  + E      +EK   +E + +R+   + ++EEK++RQE +   KE++  
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366

Query: 587 VLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFT 646
            L+   +E +  E+ R  ++   +Q+ + +  E R + E                     
Sbjct: 367 RLEEMMWEKE--EKIRELEEKMHEQEKIREQEEKRQEEE--------------------- 403

Query: 647 LKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683
            K  EQ+K+Q++  K+ RQE K +R     ++ + K+
Sbjct: 404 -KIREQEKRQEQEAKMWRQEEK-IREQEEKIREQEKK 438



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 43/198 (21%), Positives = 100/198 (50%), Gaps = 25/198 (12%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE--EKQKSTWKKKVKSLPNI 479
           E+ R+++ RQ+ EE   Q  ++++  ++ ++   K+ E+E+  ++++  W+++ K     
Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE-KMHEQEKIRKQEEKVWRQEEK----- 503

Query: 480 LTDDRFKVM------------FENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQ 527
           + D   K+                 + ++ E+ E+ R    ++ +  EK  ++   +++Q
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563

Query: 528 ELREKEEEE--EPEGKPSDAESSESSDDEKAWVEE--VRKQRRLLQ-QEEKVKRQERLKE 582
           E   ++EE+  E E K  + +      +EK W +E  +R+Q  ++Q QEEK+  QE    
Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMC 623

Query: 583 DQQTVLKPQFYEIKAGEE 600
           +Q+  ++ Q  +++  EE
Sbjct: 624 EQEEKMQEQEEKMRRQEE 641



 Score = 30.0 bits (66), Expect = 7.5
 Identities = 47/225 (20%), Positives = 86/225 (38%), Gaps = 55/225 (24%)

Query: 462 EEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKL 521
           EE  K      ++   N +TD+  K   +N   Q     E+ +L+    S+I    K+  
Sbjct: 196 EELTKERDALSLELYRNTITDEELKE--KNAKLQ-----EKLQLVESEKSEIQLNVKELK 248

Query: 522 RLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRL-LQQEEKVKRQERL 580
           R LE+ +L   +++ + E      E    S   +A VEE     RL  QQEEK+ RQE  
Sbjct: 249 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK 308

Query: 581 KEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGS 640
            ++ +  ++ Q  +I+  EE                                        
Sbjct: 309 IQEWEEKIQEQEEKIREQEE---------------------------------------- 328

Query: 641 KQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
                  K  EQ++K +  E++  ++ +++RR    +  + ++ R
Sbjct: 329 -------KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 59/251 (23%), Positives = 125/251 (49%), Gaps = 20/251 (7%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
           +E R+ ++R K EE   +R +  +L +  +E+ L+  +EEE K++   +   +     L 
Sbjct: 733 QERREAEMRAKREEEERKRQE--ELRRQQEEI-LRRQQEEERKRREEEELARRKQEEALR 789

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541
             R + +      +   E EE +     + ++ E+R+++    +Q+EL  K+EEE  +  
Sbjct: 790 RQREQEIA----LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 845

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601
             + E+    ++ +  +EE  +  RL  +EE+ KR+E   + Q+ +++ +  +    E  
Sbjct: 846 REEEEAQRRLEENRLRMEE--EAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEAL 900

Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661
           R  +    +Q+L       ++K+ + +     S+TT    Q T +L  +E QK ++E E+
Sbjct: 901 RRLQQQQQQQQLA------QMKLPSSSTWGQQSNTTACQSQATLSL--AEIQKLEEERER 952

Query: 662 LHRQERKRLRR 672
             R+E++R +R
Sbjct: 953 QLREEQRRQQR 963



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 37/169 (21%), Positives = 82/169 (48%), Gaps = 8/169 (4%)

Query: 516 KRKKKLR------LLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQ 569
           KR+++LR      L  QQE   K  EEE   +    E+     +++  +   R++    Q
Sbjct: 750 KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 809

Query: 570 QEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNG 629
           QEE ++R E  + +++   K +  E+   +E  + K +  +++   +  E+RL++E +  
Sbjct: 810 QEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 867

Query: 630 TLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLK 678
            L   +     K+L    ++   +++QQ+ E L R ++++ ++    +K
Sbjct: 868 RLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 916



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 49/197 (24%)

Query: 508 PLVSKISEKRKKKLRLLEQQ----ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRK 563
           P + ++ +  K K   LEQ+    E+R K EEEE + +                 EE+R+
Sbjct: 715 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ-----------------EELRR 757

Query: 564 QRRLL---QQEEKVKRQE-------------RLKEDQQTVLKPQFYE---------IKAG 598
           Q+  +   QQEE+ KR+E             R + +Q+  L+ Q  E         ++  
Sbjct: 758 QQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 817

Query: 599 EEFRSFKDSATKQ-KLMNKTLEDRLK--IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655
           EE R  ++   KQ +L+ K  E+  K   E +     + +  +  ++    L+  E+++K
Sbjct: 818 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 877

Query: 656 QQEAEKLHRQERKRLRR 672
           ++E E   ++E  R R+
Sbjct: 878 RKELEVQRQKELMRQRQ 894


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 59/251 (23%), Positives = 125/251 (49%), Gaps = 20/251 (7%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
           +E R+ ++R K EE   +R +  +L +  +E+ L+  +EEE K++   +   +     L 
Sbjct: 760 QERREAEMRAKREEEERKRQE--ELRRQQEEI-LRRQQEEERKRREEEELARRKQEEALR 816

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541
             R + +      +   E EE +     + ++ E+R+++    +Q+EL  K+EEE  +  
Sbjct: 817 RQREQEIA----LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 872

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601
             + E+    ++ +  +EE  +  RL  +EE+ KR+E   + Q+ +++ +  +    E  
Sbjct: 873 REEEEAQRRLEENRLRMEE--EAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEAL 927

Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661
           R  +    +Q+L       ++K+ + +     S+TT    Q T +L  +E QK ++E E+
Sbjct: 928 RRLQQQQQQQQLA------QMKLPSSSTWGQQSNTTACQSQATLSL--AEIQKLEEERER 979

Query: 662 LHRQERKRLRR 672
             R+E++R +R
Sbjct: 980 QLREEQRRQQR 990



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 37/169 (21%), Positives = 82/169 (48%), Gaps = 8/169 (4%)

Query: 516 KRKKKLR------LLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQ 569
           KR+++LR      L  QQE   K  EEE   +    E+     +++  +   R++    Q
Sbjct: 777 KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 836

Query: 570 QEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNG 629
           QEE ++R E  + +++   K +  E+   +E  + K +  +++   +  E+RL++E +  
Sbjct: 837 QEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 894

Query: 630 TLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLK 678
            L   +     K+L    ++   +++QQ+ E L R ++++ ++    +K
Sbjct: 895 RLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 943



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 49/197 (24%)

Query: 508 PLVSKISEKRKKKLRLLEQQ----ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRK 563
           P + ++ +  K K   LEQ+    E+R K EEEE + +                 EE+R+
Sbjct: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ-----------------EELRR 784

Query: 564 QRRLL---QQEEKVKRQE-------------RLKEDQQTVLKPQFYE---------IKAG 598
           Q+  +   QQEE+ KR+E             R + +Q+  L+ Q  E         ++  
Sbjct: 785 QQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 844

Query: 599 EEFRSFKDSATKQ-KLMNKTLEDRLK--IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655
           EE R  ++   KQ +L+ K  E+  K   E +     + +  +  ++    L+  E+++K
Sbjct: 845 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 904

Query: 656 QQEAEKLHRQERKRLRR 672
           ++E E   ++E  R R+
Sbjct: 905 RKELEVQRQKELMRQRQ 921


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 59/251 (23%), Positives = 125/251 (49%), Gaps = 20/251 (7%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
           +E R+ ++R K EE   +R +  +L +  +E+ L+  +EEE K++   +   +     L 
Sbjct: 739 QERREAEMRAKREEEERKRQE--ELRRQQEEI-LRRQQEEERKRREEEELARRKQEEALR 795

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541
             R + +      +   E EE +     + ++ E+R+++    +Q+EL  K+EEE  +  
Sbjct: 796 RQREQEIA----LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 851

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601
             + E+    ++ +  +EE  +  RL  +EE+ KR+E   + Q+ +++ +  +    E  
Sbjct: 852 REEEEAQRRLEENRLRMEE--EAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEAL 906

Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661
           R  +    +Q+L       ++K+ + +     S+TT    Q T +L  +E QK ++E E+
Sbjct: 907 RRLQQQQQQQQLA------QMKLPSSSTWGQQSNTTACQSQATLSL--AEIQKLEEERER 958

Query: 662 LHRQERKRLRR 672
             R+E++R +R
Sbjct: 959 QLREEQRRQQR 969



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 37/169 (21%), Positives = 82/169 (48%), Gaps = 8/169 (4%)

Query: 516 KRKKKLR------LLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQ 569
           KR+++LR      L  QQE   K  EEE   +    E+     +++  +   R++    Q
Sbjct: 756 KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 815

Query: 570 QEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNG 629
           QEE ++R E  + +++   K +  E+   +E  + K +  +++   +  E+RL++E +  
Sbjct: 816 QEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 873

Query: 630 TLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLK 678
            L   +     K+L    ++   +++QQ+ E L R ++++ ++    +K
Sbjct: 874 RLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 49/197 (24%)

Query: 508 PLVSKISEKRKKKLRLLEQQ----ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRK 563
           P + ++ +  K K   LEQ+    E+R K EEEE + +                 EE+R+
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ-----------------EELRR 763

Query: 564 QRRLL---QQEEKVKRQE-------------RLKEDQQTVLKPQFYE---------IKAG 598
           Q+  +   QQEE+ KR+E             R + +Q+  L+ Q  E         ++  
Sbjct: 764 QQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 823

Query: 599 EEFRSFKDSATKQ-KLMNKTLEDRLK--IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655
           EE R  ++   KQ +L+ K  E+  K   E +     + +  +  ++    L+  E+++K
Sbjct: 824 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 883

Query: 656 QQEAEKLHRQERKRLRR 672
           ++E E   ++E  R R+
Sbjct: 884 RKELEVQRQKELMRQRQ 900


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 59/251 (23%), Positives = 125/251 (49%), Gaps = 20/251 (7%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
           +E R+ ++R K EE   +R +  +L +  +E+ L+  +EEE K++   +   +     L 
Sbjct: 739 QERREAEMRAKREEEERKRQE--ELRRQQEEI-LRRQQEEERKRREEEELARRKQEEALR 795

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541
             R + +      +   E EE +     + ++ E+R+++    +Q+EL  K+EEE  +  
Sbjct: 796 RQREQEIA----LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 851

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601
             + E+    ++ +  +EE  +  RL  +EE+ KR+E   + Q+ +++ +  +    E  
Sbjct: 852 REEEEAQRRLEENRLRMEE--EAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEAL 906

Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661
           R  +    +Q+L       ++K+ + +     S+TT    Q T +L  +E QK ++E E+
Sbjct: 907 RRLQQQQQQQQLA------QMKLPSSSTWGQQSNTTACQSQATLSL--AEIQKLEEERER 958

Query: 662 LHRQERKRLRR 672
             R+E++R +R
Sbjct: 959 QLREEQRRQQR 969



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 37/169 (21%), Positives = 82/169 (48%), Gaps = 8/169 (4%)

Query: 516 KRKKKLR------LLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQ 569
           KR+++LR      L  QQE   K  EEE   +    E+     +++  +   R++    Q
Sbjct: 756 KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 815

Query: 570 QEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNG 629
           QEE ++R E  + +++   K +  E+   +E  + K +  +++   +  E+RL++E +  
Sbjct: 816 QEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 873

Query: 630 TLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLK 678
            L   +     K+L    ++   +++QQ+ E L R ++++ ++    +K
Sbjct: 874 RLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 49/197 (24%)

Query: 508 PLVSKISEKRKKKLRLLEQQ----ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRK 563
           P + ++ +  K K   LEQ+    E+R K EEEE + +                 EE+R+
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ-----------------EELRR 763

Query: 564 QRRLL---QQEEKVKRQE-------------RLKEDQQTVLKPQFYE---------IKAG 598
           Q+  +   QQEE+ KR+E             R + +Q+  L+ Q  E         ++  
Sbjct: 764 QQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 823

Query: 599 EEFRSFKDSATKQ-KLMNKTLEDRLK--IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655
           EE R  ++   KQ +L+ K  E+  K   E +     + +  +  ++    L+  E+++K
Sbjct: 824 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 883

Query: 656 QQEAEKLHRQERKRLRR 672
           ++E E   ++E  R R+
Sbjct: 884 RKELEVQRQKELMRQRQ 900


>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
          Length = 495

 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 63/254 (24%), Positives = 127/254 (50%), Gaps = 25/254 (9%)

Query: 420 AYEEYRKDKIR-QKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPN 478
           AYE+  K+K+   +I     +  QL+K  K+ K  A++   EE +K+++ W+KK +    
Sbjct: 205 AYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKRE--E 262

Query: 479 ILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEP 538
           +  ++R  + F N    + ++ EE R+     +K+ E  +K+L+L  Q  L +K EE   
Sbjct: 263 MEEENRKIIEFAN----MQQQREEDRM-----AKVQENEEKRLQL--QNALTQKLEEMLR 311

Query: 539 EGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED--QQTVLKPQFYEIK 596
           + +  +    E   +E+A   E+ K +   + E+K+++Q+ +K+D  +Q  LK    +  
Sbjct: 312 QREDLEQVRQELYQEEQA---EIYKSKLKEEAEKKLRKQKEMKQDFEEQMALKELVLQ-A 367

Query: 597 AGEEFRSFKDSATKQKLMNKTLEDRLKI-EAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655
           A EE  +F+    K  L     +DR+++  A+   +   +     ++L    ++     K
Sbjct: 368 AKEEEENFR----KTMLAKFAEDDRIELMNAQKQRMKQLEHRRAVEKLIEERRQQFLADK 423

Query: 656 QQEAEKLHRQERKR 669
           Q+E E+   Q+R++
Sbjct: 424 QRELEEWQLQQRRQ 437



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 44/260 (16%), Positives = 120/260 (46%), Gaps = 47/260 (18%)

Query: 427 DKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFK 486
           ++ ++ ++E   +++ ++ L  VN ++  ++++ E + +        K    +L +++F+
Sbjct: 12  ERHQKLVDENYCKKLHVQALKNVNSQIRNQMVQNENDNRVQR-----KQFLRLLQNEQFE 66

Query: 487 VMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKE----------EEE 536
           +  E    +  +++EE + L  L  K  EK   +L  L+ + L++++          E  
Sbjct: 67  LDME----EAIQKAEENKRLKELQLKQEEKLAMELAKLKHESLKDEKMRQQVRENSIELR 122

Query: 537 EPEGKPSDA-----ESSESSDDEKAWVEEVRKQ----RRLLQQEEKVKRQERLKEDQQTV 587
           E E K   A      +++ ++ +    E++++     + ++++ +++ ++E   ED++  
Sbjct: 123 ELEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKEENAAEDKRNK 182

Query: 588 LKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTL 647
            K Q+Y      E +  +    KQ+   + L+++L I+                ++   +
Sbjct: 183 AKAQYY---LDLEKQLEEQEKKKQEAYEQLLKEKLMID----------------EIVRKI 223

Query: 648 KRSEQQKKQQEAEKLHRQER 667
              +Q +KQQ+ EK++   R
Sbjct: 224 YEEDQLEKQQKLEKMNAMRR 243



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 54/260 (20%), Positives = 111/260 (42%), Gaps = 36/260 (13%)

Query: 421 YEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL 480
           +E   ++ I++  E  R + +QLK+  K+  ELA KL  E  + +K   + +  S+    
Sbjct: 65  FELDMEEAIQKAEENKRLKELQLKQEEKLAMELA-KLKHESLKDEKMRQQVRENSIELRE 123

Query: 481 TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540
            + + K  + N      E + +    + +  +  ++  +  + + ++  R  +EE   E 
Sbjct: 124 LEKKLKAAYMN-----KERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKEENAAED 178

Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQ--EEKVKRQE---RLKEDQQTVLKPQFYEI 595
           K + A++    D EK   E+ +K++   +Q  +EK+   E   ++ E+ Q   + +  ++
Sbjct: 179 KRNKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKM 238

Query: 596 KAG----EEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSE 651
            A     EEF+  +    K+K      E+R  IE  N                      +
Sbjct: 239 NAMRRYIEEFQKEQALWRKKKREEMEEENRKIIEFAN---------------------MQ 277

Query: 652 QQKKQQEAEKLHRQERKRLR 671
           QQ+++    K+   E KRL+
Sbjct: 278 QQREEDRMAKVQENEEKRLQ 297



 Score = 37.4 bits (85), Expect = 0.047
 Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 19/127 (14%)

Query: 421 YEEYRKDKIRQKIEETRAQRVQLKKLPKVN-------KELALKLIEEEEEKQKSTWKKKV 473
           Y+E + +  + K++E   ++++ +K  K +       KEL L+  +EEEE  + T     
Sbjct: 324 YQEEQAEIYKSKLKEEAEKKLRKQKEMKQDFEEQMALKELVLQAAKEEEENFRKTM---- 379

Query: 474 KSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKE 533
             L     DDR ++M  N   Q  ++ E  R     V K+ E+R+++    +Q+EL E +
Sbjct: 380 --LAKFAEDDRIELM--NAQKQRMKQLEHRRA----VEKLIEERRQQFLADKQRELEEWQ 431

Query: 534 EEEEPEG 540
            ++  +G
Sbjct: 432 LQQRRQG 438


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 65/249 (26%), Positives = 112/249 (44%), Gaps = 39/249 (15%)

Query: 427  DKIRQKIEETRAQRVQLKKLPKVNKELALKLIEE---EEEKQKSTWKKKVKSLPNILTDD 483
            +K+R+ I +      +  KL + + E+ L   EE   EEE+     K++ +        D
Sbjct: 2148 NKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGD 2207

Query: 484  RFKVMFENPDFQVDE-ESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542
            + K  F +   QVDE ESEE           SE+ +  L  LE+QE    EEEEE E + 
Sbjct: 2208 KPKEKFSS---QVDEVESEEH---------FSEEMESLLDELEKQESLSSEEEEEREEEE 2255

Query: 543  SDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFR 602
               E     ++E+   EE  +++++ ++EE+ K++++ K+ ++   K + +E K  EE  
Sbjct: 2256 EREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK--EEIM 2313

Query: 603  SFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKL 662
            S                     E +  +LS  +    S  L   + R ++  K+++  KL
Sbjct: 2314 S---------------------EEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKL 2352

Query: 663  HRQERKRLR 671
              Q RK LR
Sbjct: 2353 QEQRRKSLR 2361



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 63/297 (21%), Positives = 131/297 (44%), Gaps = 53/297 (17%)

Query: 422  EEYRKDKIRQKIEETRAQRVQL-KKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL 480
            EE++  +I +K      +R Q  +KL +  ++LA     +EE +     +K  ++   I 
Sbjct: 1570 EEHKWARIHRKRARAEKKRAQEERKLAQEEEKLA-----QEERQLAQEERKLAQAYVKIT 1624

Query: 481  TDDRFKVMFENPDFQVDEE-SEEFRLLNPLVSKISEKRKK-------------KL----- 521
             DDR     E    Q +E  ++    L+    K+++KRKK             KL     
Sbjct: 1625 QDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGG 1684

Query: 522  RLLEQQELREKEEEEEPEGKPS----------DAESSESSDDEKAWVEE---------VR 562
            +L E + +  ++ EE P+ + +          + E  E   +E +W EE         V 
Sbjct: 1685 KLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVE 1744

Query: 563  KQRRLLQQEEKVK-RQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQ-----KLMNK 616
            ++++L ++EE +  ++E+L E++  + + +   I+  E+    K+   ++     +   +
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQ 1804

Query: 617  TLEDRLKIEAKNGT-LSVSDTTVGSKQLTFTLKRSEQQKKQ--QEAEKLHRQERKRL 670
             +E ++K+  K    ++  +    +K + +  K   Q+KK   QE EKL +++   L
Sbjct: 1805 LIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLL 1861



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 67/292 (22%), Positives = 125/292 (42%), Gaps = 52/292 (17%)

Query: 430  RQKIEETRAQRVQLK-KLPKVNKELAL---KLIEEEE------EKQKSTWKKKVKSLPNI 479
            ++++  ++ Q VQ+K KL   NK LA    KL +E+E      EK   T KK V+   ++
Sbjct: 1864 KERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSL 1923

Query: 480  ------LTDDRFKVMFENPDFQVDEE-------SEEFRLLNPLVSKISEKRKKKLRLLEQ 526
                  L  ++ K+  E    Q  +        ++E + LN  + +++E   +K+RL+E 
Sbjct: 1924 AKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAE---EKMRLVEG 1980

Query: 527  QELREKEEEEEPEGKPSDAESSESSDDEKAWVEE--VRKQRRLLQQEEK--VKRQERLKE 582
            +E   K E  E   +    +  +   + K  +EE  +  + R+L  EE    K +     
Sbjct: 1981 KETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTR 2040

Query: 583  DQQTVLKPQFYEIKAGEEFRSFKDSATKQ--------KLMNKTLEDRLKIE--------- 625
             Q+  ++ Q    KA  +    ++S +K+        K + K   D  K+          
Sbjct: 2041 GQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKM 2100

Query: 626  -----AKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRR 672
                  K   LS+  + +  K+  F+ KRSE  K +++  +  R+   ++RR
Sbjct: 2101 KRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRR 2152



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 60/272 (22%), Positives = 118/272 (43%), Gaps = 42/272 (15%)

Query: 432  KIEETRAQRVQL---KKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRF--- 485
            K+E TR QR+ +   +KL K +++L  K   E   K+ +   K +K+L  +  D+R    
Sbjct: 2035 KLEFTRGQRIFVQGQRKLAKASRKLIKK--RESLSKEPAKLNKILKALQKLTRDERKLTQ 2092

Query: 486  -----------------KVMFENPDFQVDEE--SEEFRLLNPLVSKISEKRKK---KLRL 523
                             ++  E     + E   SE+   L     K++ K++K   K+R 
Sbjct: 2093 EEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRR 2152

Query: 524  LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEE---VRKQRRLLQQEEKVKRQERL 580
            +  +E +  EEE +   K S+       D+E+  +EE   +   +R  ++ ++ KR ++ 
Sbjct: 2153 MINKEEKMTEEESKLARKHSEVILD---DEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKP 2209

Query: 581  KEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGS 640
            KE   + +     E    EE  S  D   KQ+ ++   E+  + E +     V +     
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269

Query: 641  KQLTFTLKRSEQQKKQQEAEKLHRQERKRLRR 672
            K+        E ++KQ E E+  ++++K+ ++
Sbjct: 2270 KE------EEEGEEKQVEKEEEEKKKKKKEKK 2295



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 75/285 (26%), Positives = 128/285 (44%), Gaps = 39/285 (13%)

Query: 422  EEYRKDKIRQKI--EETRAQRVQLKKLPKV------NKELALKLIEEEEEK--QKSTWKK 471
            EE  + K R  +  EET+   V LKK  KV      N  +  ++ ++EE+K  QKS  K+
Sbjct: 1347 EEQAQKKARDMLGLEETQ---VILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSP-KQ 1402

Query: 472  KVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELRE 531
              K++       + K      +  + EE EE   L   V K    ++ KL ++E+    +
Sbjct: 1403 GRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVK----QEGKLVMIERTPSWQ 1458

Query: 532  KEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKR--------QERLKED 583
              ++   E K    E+ +S    KAW EE  K  RLLQ+EEK+ +        +E L+ED
Sbjct: 1459 DWKKAWDEWKQVHGETRKSW---KAWKEEWEK--RLLQEEEKLHQAGEKLSPEEEMLQED 1513

Query: 584  QQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNK-TLEDRLKIEAKNGTLSVSDTT----V 638
            ++  LK + ++ +  E   S K    + K   + TLE+ +  E +     V++       
Sbjct: 1514 KK--LKWEEWK-QVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQE 1570

Query: 639  GSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683
              K      KR+  +KK+ + E+   QE ++L +    L    ++
Sbjct: 1571 EHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERK 1615



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 40/177 (22%), Positives = 86/177 (48%), Gaps = 24/177 (13%)

Query: 426  KDKIRQKIEETRAQRVQLKKLPKVNKELALK--LIEEEEEKQKSTWKKKVKSLPNILTDD 483
            K+K   +++E  ++    +++  +  EL  +  L  EEEE+++   +++ +         
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEE--------- 2260

Query: 484  RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPS 543
              +V  E  + + +EE EE +     V K  E++KKK      ++ ++KEE +E E    
Sbjct: 2261 --EVREEEEERKEEEEGEEKQ-----VEKEEEEKKKK------KKEKKKEEVQEKEEVFE 2307

Query: 544  DAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600
            + E   S ++ ++  +E  ++     +EE  + +E LK+++Q  L+ Q  +   G E
Sbjct: 2308 EKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRE 2364



 Score = 37.7 bits (86), Expect = 0.036
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 55/224 (24%)

Query: 466  KSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEES--EEFRLL--NPLVSKISEKRKKKL 521
            K  W+K++      L     K+  E    Q D++   EE++ +  N L SK  E++ K  
Sbjct: 1482 KEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDE 1541

Query: 522  R--LLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRK-----------QRRLL 568
                LE++  RE EE+E+        E      +E  W    RK           +R+L 
Sbjct: 1542 EEVTLEEEVSREGEEKEQQV-----TEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLA 1596

Query: 569  QQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKN 628
            Q+EEK+ ++ER    ++  L   + +I                     T +DR   +A+ 
Sbjct: 1597 QEEEKLAQEERQLAQEERKLAQAYVKI---------------------TQDDREMAQAE- 1634

Query: 629  GTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRR 672
            G  +  + T+  +           +K  QEAEKL  Q+RK+L +
Sbjct: 1635 GKFAQKEETLAQR----------GEKLSQEAEKL-AQKRKKLAK 1667



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 31/118 (26%), Positives = 63/118 (53%), Gaps = 7/118 (5%)

Query: 422  EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
            EE R+++  ++ EE R +  + K+  +  ++   K  EE+++K+K   K++V+    +  
Sbjct: 2248 EEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVF- 2306

Query: 482  DDRFKVMF--ENPDFQVDEESEEFRLLNPLVSKISE--KRKKKLRLLEQ--QELREKE 533
            +++ ++M   E      +EE EE   L   V +  E  K++K+ +L EQ  + LR +E
Sbjct: 2307 EEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRE 2364



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 51/254 (20%), Positives = 116/254 (45%), Gaps = 28/254 (11%)

Query: 433  IEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKK--VKSLPNILTDDRFKVMFE 490
            I+E        +K+P+  + L  K  +  E+K K   K++  + S+   LT ++  +   
Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEE-LTKNKMIL--- 1833

Query: 491  NPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSES 550
               +Q    ++E + L     K+++ RK+ L   +++    K++  + + K        +
Sbjct: 1834 ---YQKKNLAQEKKNLAQEKEKLAQ-RKENLLYNKERLTHSKKQLVQVKNKLGMFNKILA 1889

Query: 551  SDDEKAWVEE---VRKQRRLLQQEEKV--------KRQERLKEDQQTVLKPQFYEIKAGE 599
              +EK   E+   ++K+ +L + E+K+        K+QE+L +++  +   +   ++  +
Sbjct: 1890 QVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAM-VQGKK 1948

Query: 600  EFRSFKDSATKQKLMN----KTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSE--QQ 653
              R   D A ++K +N    +  E+++++     TLS  +T   S+Q   T    E  ++
Sbjct: 1949 RLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFER 2008

Query: 654  KKQQEAEKLHRQER 667
            K   E + L  ++R
Sbjct: 2009 KLSLEEKILLHEDR 2022


>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
           1 [Homo sapiens]
          Length = 1722

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 60/248 (24%), Positives = 120/248 (48%), Gaps = 20/248 (8%)

Query: 425 RKDKIRQKIEETR-----AQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNI 479
           R++K  Q+ EE R       +V+ KKL  + K+   K+  +E  K++  WK+K K     
Sbjct: 195 REEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKM-NDELYKEEKIWKEKFKQHEEY 253

Query: 480 LTDDRFKVMFENPDFQVDEESEEFRLL---NPLVSKISEKRK------KKLRLLEQQELR 530
           + +   ++  E   F+  +E E+  LL   N    KI  K K      K   ++++Q   
Sbjct: 254 IRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIES 313

Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKP 590
           +K + +E + K +     E  + ++   E+  K+ R  Q+EE+ KR+E+  E+++ ++K 
Sbjct: 314 KKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQ 373

Query: 591 QFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRS 650
           +  ++ + E+    ++ A++Q +++  L+   K    N  LS+ D +     +   L   
Sbjct: 374 EREQLISKEKI-ILREDASQQLIISSALK---KSGYNNKHLSLEDISNDKGDIAKNLV-D 428

Query: 651 EQQKKQQE 658
           E  KKQ++
Sbjct: 429 ENSKKQED 436



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 46/235 (19%), Positives = 109/235 (46%), Gaps = 29/235 (12%)

Query: 458 IEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKR 517
           +EE+  +    W++K K L     +D+ K   +    Q D E ++F+          E+ 
Sbjct: 163 VEEKCRQSFEAWQEKQKEL-----EDKEKQTLKA---QRDREEKQFQ----------EEE 204

Query: 518 KKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQR------RLLQQE 571
           +K+   ++Q ++ EK++ E  + +  D  + E   +EK W E+ ++         L  +E
Sbjct: 205 EKRHCWMKQFKV-EKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEE 263

Query: 572 EKVKRQERLKEDQQTVLKPQ-FYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGT 630
           E+ + +++ ++++ ++LK Q    +K   ++++F        ++ + +E +   + K   
Sbjct: 264 ERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESK---KRKAQE 320

Query: 631 LSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
               +  +  K+     +  E+Q+ ++E +K   +ERKR  +     K+  K+ R
Sbjct: 321 WKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQER 375



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 62/279 (22%), Positives = 128/279 (45%), Gaps = 38/279 (13%)

Query: 425 RKDKIRQKIEETRA---QRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPN--- 478
           ++ KIRQK EE R    +  ++K+  K  KE   K  E+E E++K+  K++ + L +   
Sbjct: 324 KEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEK 383

Query: 479 -ILTDDRFKVM----------FENPDFQVDEES-EEFRLLNPLVSKISEKRKKKLR-LLE 525
            IL +D  + +          + N    +++ S ++  +   LV + S+K++  L  L+E
Sbjct: 384 IILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVE 443

Query: 526 QQELREKEE-----EEEPEGKPSDAESSES------SDDEKAWVEEVRKQRRLLQQEEKV 574
           +  ++E  +     +E  + K  ++ SS++       +++   + + R    L++QE K 
Sbjct: 444 ESNMKENVDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQERKY 503

Query: 575 KRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAK---NGTL 631
           +  +   E   + LK    E    +E +S  D+  ++K+M   + +    + +       
Sbjct: 504 ENTDNKTELGNSDLKGNLKEQFPLQELKS--DAQKEEKIMKHVINENTGQKTQIILGHNQ 561

Query: 632 SVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRL 670
            +S+     +Q    + +  QQKK Q+ EK   QE+  L
Sbjct: 562 EISEVKTNEEQ---KIIKDNQQKKIQKVEKEEIQEQNGL 597



 Score = 30.4 bits (67), Expect = 5.7
 Identities = 44/192 (22%), Positives = 76/192 (39%), Gaps = 40/192 (20%)

Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQ------------- 577
           E EE+     +    +  E  D EK  ++  R +     QEE+ KR              
Sbjct: 162 EVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKL 221

Query: 578 ERLKEDQQTVLKPQFYE--------------------IKAGEEFRSFKDSATKQK--LMN 615
           E +++ +Q  +  + Y+                    ++  EE   FKD   K+K  L+ 
Sbjct: 222 ENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLK 281

Query: 616 KTLEDRLKIEAKNGTLSVSDTTVGS--KQLTFTLKRSEQQKKQQEAEKLHRQE--RKRLR 671
           +     +KI+AK     V+    G   K+   + KR  Q+ K++EA+   ++E  RKRL 
Sbjct: 282 QQNNAAVKIQAKYKAF-VAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLE 340

Query: 672 RSAGHLKSRHKR 683
                 + R K+
Sbjct: 341 EEQRIKEERKKQ 352


>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
           2 [Homo sapiens]
          Length = 1336

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 60/248 (24%), Positives = 120/248 (48%), Gaps = 20/248 (8%)

Query: 425 RKDKIRQKIEETR-----AQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNI 479
           R++K  Q+ EE R       +V+ KKL  + K+   K+  +E  K++  WK+K K     
Sbjct: 195 REEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKM-NDELYKEEKIWKEKFKQHEEY 253

Query: 480 LTDDRFKVMFENPDFQVDEESEEFRLL---NPLVSKISEKRK------KKLRLLEQQELR 530
           + +   ++  E   F+  +E E+  LL   N    KI  K K      K   ++++Q   
Sbjct: 254 IRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIES 313

Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKP 590
           +K + +E + K +     E  + ++   E+  K+ R  Q+EE+ KR+E+  E+++ ++K 
Sbjct: 314 KKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQ 373

Query: 591 QFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRS 650
           +  ++ + E+    ++ A++Q +++  L+   K    N  LS+ D +     +   L   
Sbjct: 374 EREQLISKEKI-ILREDASQQLIISSALK---KSGYNNKHLSLEDISNDKGDIAKNLV-D 428

Query: 651 EQQKKQQE 658
           E  KKQ++
Sbjct: 429 ENSKKQED 436



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 46/235 (19%), Positives = 109/235 (46%), Gaps = 29/235 (12%)

Query: 458 IEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKR 517
           +EE+  +    W++K K L     +D+ K   +    Q D E ++F+          E+ 
Sbjct: 163 VEEKCRQSFEAWQEKQKEL-----EDKEKQTLKA---QRDREEKQFQ----------EEE 204

Query: 518 KKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQR------RLLQQE 571
           +K+   ++Q ++ EK++ E  + +  D  + E   +EK W E+ ++         L  +E
Sbjct: 205 EKRHCWMKQFKV-EKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEE 263

Query: 572 EKVKRQERLKEDQQTVLKPQ-FYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGT 630
           E+ + +++ ++++ ++LK Q    +K   ++++F        ++ + +E +   + K   
Sbjct: 264 ERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESK---KRKAQE 320

Query: 631 LSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
               +  +  K+     +  E+Q+ ++E +K   +ERKR  +     K+  K+ R
Sbjct: 321 WKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQER 375



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 62/279 (22%), Positives = 128/279 (45%), Gaps = 38/279 (13%)

Query: 425 RKDKIRQKIEETRA---QRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPN--- 478
           ++ KIRQK EE R    +  ++K+  K  KE   K  E+E E++K+  K++ + L +   
Sbjct: 324 KEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEK 383

Query: 479 -ILTDDRFKVM----------FENPDFQVDEES-EEFRLLNPLVSKISEKRKKKLR-LLE 525
            IL +D  + +          + N    +++ S ++  +   LV + S+K++  L  L+E
Sbjct: 384 IILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVE 443

Query: 526 QQELREKEE-----EEEPEGKPSDAESSES------SDDEKAWVEEVRKQRRLLQQEEKV 574
           +  ++E  +     +E  + K  ++ SS++       +++   + + R    L++QE K 
Sbjct: 444 ESNMKENVDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQERKY 503

Query: 575 KRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAK---NGTL 631
           +  +   E   + LK    E    +E +S  D+  ++K+M   + +    + +       
Sbjct: 504 ENTDNKTELGNSDLKGNLKEQFPLQELKS--DAQKEEKIMKHVINENTGQKTQIILGHNQ 561

Query: 632 SVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRL 670
            +S+     +Q    + +  QQKK Q+ EK   QE+  L
Sbjct: 562 EISEVKTNEEQ---KIIKDNQQKKIQKVEKEEIQEQNGL 597



 Score = 30.4 bits (67), Expect = 5.7
 Identities = 44/192 (22%), Positives = 76/192 (39%), Gaps = 40/192 (20%)

Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQ------------- 577
           E EE+     +    +  E  D EK  ++  R +     QEE+ KR              
Sbjct: 162 EVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKL 221

Query: 578 ERLKEDQQTVLKPQFYE--------------------IKAGEEFRSFKDSATKQK--LMN 615
           E +++ +Q  +  + Y+                    ++  EE   FKD   K+K  L+ 
Sbjct: 222 ENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLK 281

Query: 616 KTLEDRLKIEAKNGTLSVSDTTVGS--KQLTFTLKRSEQQKKQQEAEKLHRQE--RKRLR 671
           +     +KI+AK     V+    G   K+   + KR  Q+ K++EA+   ++E  RKRL 
Sbjct: 282 QQNNAAVKIQAKYKAF-VAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLE 340

Query: 672 RSAGHLKSRHKR 683
                 + R K+
Sbjct: 341 EEQRIKEERKKQ 352


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 56/282 (19%), Positives = 138/282 (48%), Gaps = 31/282 (10%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE----------EKQKSTWKK--K 472
           +++KIR++ E+ R Q  ++++  ++  E   K+  +EE           +++  W+K  K
Sbjct: 380 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439

Query: 473 VKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE-LRE 531
           ++ L   + +   K+  +    Q +E+  E        +K+  + +K   + EQ+E +RE
Sbjct: 440 IRELEEKMHEQE-KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK---IREQEEKIRE 495

Query: 532 KEE-----EEEPEGKPSDAESSESSDDEKAWVEE--VRKQRRLLQQEEKVKRQE-RLKED 583
           +EE     EE+   +    E  +  + E+ W +E  +R+Q  + +Q+EK+  QE ++++ 
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555

Query: 584 QQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQL 643
           ++ + + +       E+ R  ++   +Q+   +  E++++ E +       + T   ++ 
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR-EQEEKIREQEEMTQEQEE- 613

Query: 644 TFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
               K  EQ++K  E E+  +++ +++RR    ++ + K+ R
Sbjct: 614 ----KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 56/264 (21%), Positives = 128/264 (48%), Gaps = 32/264 (12%)

Query: 425 RKDKIRQKIEETRAQRVQL-KKLPKVNKELALKLIEEEEEKQKSTWKK--KVKSLPNILT 481
           +++KIR++ E+ R Q  ++ ++  K++++  ++  EE+ ++Q+  W++  K++    I  
Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE-EEKRQEQEEMWRQEEKIREQEEIWR 540

Query: 482 DDRFKVMFENPDFQVDEES--EEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE-EEP 538
               K+  +    +  EE    +   ++    KI E+ +K  R  +++++RE+EE+  E 
Sbjct: 541 QKE-KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWR--QEEKIREQEEKIREQ 597

Query: 539 EGKPSDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEI 595
           E K  + E      +EK   +E +   ++ ++ +QEEK++RQE    +Q+  ++ Q  +I
Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657

Query: 596 KAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655
           +  EE    ++    ++   K  E   K++ +                    K   Q++K
Sbjct: 658 REQEEMMQEQEEKMWEQ-EEKMCEQEEKMQEQEE------------------KMRRQEEK 698

Query: 656 QQEAEKLHRQERKRLRRSAGHLKS 679
             E E   RQ+ ++++    HL++
Sbjct: 699 MWEQEVRLRQQEEKMQEHQEHLEA 722



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 56/283 (19%), Positives = 125/283 (44%), Gaps = 59/283 (20%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKK--KVKSLPNILTD 482
           +++KIR+  E+   Q    ++  K  +E  ++  E+ +E++   W++  K++     + +
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495

Query: 483 DRFKV------MFENPDFQVDEESEEFRLLNPLVSKISEKR---KKKLRLLEQQELREKE 533
              K+      + E    + +E+ +E   +     KI E+    ++K ++ EQ+E   K+
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555

Query: 534 EEE--EPEGKPSDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQE---------- 578
           EE+    E K  D E      +EK W +E +   ++ ++ +QEEK++ QE          
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615

Query: 579 ------------RLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEA 626
                       +++E ++ + + +    +  ++ R  ++   +Q+ M +  E+++  + 
Sbjct: 616 GEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675

Query: 627 KNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQE-AEKLHRQERK 668
           +                    K  EQ++K QE  EK+ RQE K
Sbjct: 676 E--------------------KMCEQEEKMQEQEEKMRRQEEK 698



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 59/277 (21%), Positives = 117/277 (42%), Gaps = 42/277 (15%)

Query: 425 RKDKIRQKIEETRAQR----VQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKS 475
           +K K  + IEE   +R    ++L +    ++EL  K  + +E     E +KS  +  VK 
Sbjct: 248 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 307

Query: 476 LPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE 535
           L   L   +  +  +    + D   +E + ++  +    E+ +   RL +QQE +   +E
Sbjct: 308 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 367

Query: 536 E-----------------EPEGKPSDAESSESSDDEKAWVEEVRKQRR---LLQQEEKVK 575
           E                 E E K  + E      +E  W +E + +R+   + ++EEK++
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 427

Query: 576 RQERL---KEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLS 632
           RQE +   KE++   L+ + +E +   E    +    K +   K  E   K+  +   + 
Sbjct: 428 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 487

Query: 633 VSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKR 669
             +  +          R +++K  ++ EK+H QE+ R
Sbjct: 488 EQEEKI----------REQEEKMWRQEEKIHEQEKIR 514



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 46/196 (23%), Positives = 97/196 (49%), Gaps = 26/196 (13%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEK----QKSTWKKKVKSLP 477
           E+ R+++ RQ+ EE   Q  ++++  ++ ++   + I E+EEK    ++  W+++ K   
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQK--EKIHEQEEKIRKQEEKMWRQEEK--- 565

Query: 478 NILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE- 536
             + D   K+     + +V  + E+ R     + +  EK +++  + ++QE +  E+EE 
Sbjct: 566 --MHDQEEKI--REQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 621

Query: 537 --EPEGKPSDAESSESSDDEKAWVEE---------VRKQRRLLQ-QEEKVKRQERLKEDQ 584
             E E K  + E      +EK   +E         +R+Q  ++Q QEEK+  QE    +Q
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 681

Query: 585 QTVLKPQFYEIKAGEE 600
           +  ++ Q  +++  EE
Sbjct: 682 EEKMQEQEEKMRRQEE 697



 Score = 34.7 bits (78), Expect = 0.30
 Identities = 30/134 (22%), Positives = 64/134 (47%), Gaps = 10/134 (7%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWK-----KKVKSLPNI 479
           +++KIR++ E+ R Q    ++  +   E   K+ E+EE+ Q+   K     +K++     
Sbjct: 590 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK 649

Query: 480 LTDDRFKVMFENPDFQVDEES--EEFRLLNPLVSKISEKRKKKLRLLE---QQELREKEE 534
           + +   K+  +    Q  EE   E+   +     K+ E+ +K  R  E   +QE+R +++
Sbjct: 650 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709

Query: 535 EEEPEGKPSDAESS 548
           EE+ +      E++
Sbjct: 710 EEKMQEHQEHLEAA 723


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 57/260 (21%), Positives = 119/260 (45%), Gaps = 16/260 (6%)

Query: 436 TRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKK-VKSLPNILTDDRFKVMFENPDF 494
           T A R  +K   K N  L +   E+E ++ ++  +K+  + L     ++  +   E    
Sbjct: 509 TSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL 568

Query: 495 QVDEESEEFRLLNPLVSKISEKRKK----KLRLLEQQELREKEEE--EEPEGKPSDAESS 548
           + +E   +       V ++ E++KK    K   ++++  + KEE   EE   K + A+  
Sbjct: 569 KREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 628

Query: 549 ESSDDEKAWVEEVRKQRRLLQQEEKVKRQERL---KEDQQTVLKPQFYEIKAGEEFRSFK 605
           E  +  +   EE R+ R L Q+EE+ + QE L   KE++Q  L+      KA E  R  +
Sbjct: 629 EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLR------KAAEAKRLAE 682

Query: 606 DSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQ 665
               +++   +  ++R + E +       +  +  ++     +R + +++ QE EK  R 
Sbjct: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 742

Query: 666 ERKRLRRSAGHLKSRHKRGR 685
           ++++L+R     K + ++ R
Sbjct: 743 QKEQLQRELEEKKKKEEQQR 762



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 59/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQK------STWKKKVKSLPN 478
           R++++R K+ + R +  Q+K+  K   E     I+E+ EK K         KKK  +   
Sbjct: 570 REERLR-KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 628

Query: 479 ILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKL-------RLLEQQELRE 531
              + R K   E    +  ++ EE R    L+ K  E+ +++L       RL EQ+E   
Sbjct: 629 EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 688

Query: 532 KEEE-EEPEGKPSDAESSESSDDEKAWVE-EVRKQRRLLQQEEKVKRQERLKEDQQTVLK 589
           +E+E  E E +  +    E  + E+   E E R+++  LQ E +++ +E+    Q+  L+
Sbjct: 689 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 748

Query: 590 PQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLT 644
            +  E K  EE +   +   +++   K  E     +A N T+ V      S Q+T
Sbjct: 749 RELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMT 803


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 50/261 (19%), Positives = 113/261 (43%), Gaps = 14/261 (5%)

Query: 430 RQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKV----KSLPNILTDDRF 485
           +++  E+R +R ++++   V K        + EE +K   +K+     K     + +++ 
Sbjct: 149 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQV 208

Query: 486 KVMFENPDFQVDEESEEFRLLNPLVS----KISEKRKKKLRLLEQQELREKEEEEEPEGK 541
           +VM E    +  EE+    L N  +S    K  E+R++    +   E  E+E++E  E +
Sbjct: 209 EVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAE 268

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601
            +  E+ E    +    +++  +R  ++ EEK   QER + + +   + +  E +A EE 
Sbjct: 269 RARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEER 328

Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661
           +  K+         +  E+R +I+ +    +     +  ++     +R   + +++E  K
Sbjct: 329 QRIKEEE------KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAK 382

Query: 662 LHRQERKRLRRSAGHLKSRHK 682
           +  Q+R +      H     K
Sbjct: 383 VEEQKRNKQLEEKKHAMQETK 403



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 55/265 (20%), Positives = 121/265 (45%), Gaps = 24/265 (9%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481
           EE R  + RQ+I+E   +  + ++  +  +E   K+  EE+++ K   +KK       + 
Sbjct: 348 EEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKV--EEQKRNKQLEEKKHAMQETKIK 405

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541
            ++ +   E   +  +++++E +L   ++ K  E++  K+     Q  REK +E++P  K
Sbjct: 406 GEKVEQKIEGK-WVNEKKAQEDKLQTAVLKKQGEEKGTKV-----QAKREKLQEDKPTFK 459

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQE------RLKEDQQTVLKP---QF 592
             + +  +   D++   EEV+      +   +VK Q       +LK  + T  +P     
Sbjct: 460 KEEIKDEKIKKDKEP-KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRAS 518

Query: 593 YEIKAGEEFRSFKDSATKQKLMNKTLE------DRLKIEAKNGTLSVSDTTVGSKQLTFT 646
            + K  E     +     ++L  +  E      ++LK + +   L + +     ++    
Sbjct: 519 VDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 578

Query: 647 LKRSEQQKKQQEAEKLHRQERKRLR 671
           L+  EQ++KQ+EA++  R+E ++ R
Sbjct: 579 LEEEEQRRKQEEADRKLREEEEKRR 603



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 64/300 (21%), Positives = 125/300 (41%), Gaps = 74/300 (24%)

Query: 423 EYRKDKIRQKIEETR--AQRVQLKKLPKVNKELA-----------LKLIEEEEEKQKSTW 469
           E R++  RQK EE R  A+R+  ++     +E A           L+  +EEE   + T 
Sbjct: 5   ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64

Query: 470 KKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQEL 529
           + +V +  N + D+  K    N   + D+E+     L    ++  E+R+K+L     QE 
Sbjct: 65  QVEVNA-QNSVPDEEAKTTTTNTQVEGDDEAAFLERL----ARREERRQKRL-----QEA 114

Query: 530 REKEEEEEP-------------------EGKPSDAESSESSDDEKAWVEEVRKQRRLLQQ 570
            E+++E +P                   E + ++ E    S  E+  +EE     +  Q+
Sbjct: 115 LERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 174

Query: 571 -----------EEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLE 619
                      E+K K +E  ++ ++  +     E+   E+               ++ E
Sbjct: 175 NDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEK-------------TTESQE 221

Query: 620 DRLKIEAKNGTLS------VSDTTVGSKQLTFTLKRSEQQKKQQEAE--KLHRQERKRLR 671
           + + +  KNG +S        +   GS +++   K  E+ K++ EAE  +L  +ER+R++
Sbjct: 222 ETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIK 281



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 49/252 (19%), Positives = 113/252 (44%), Gaps = 39/252 (15%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIE-EEEEKQKSTWKKKVKSLPNIL 480
           EE ++++ R++  +  +   ++++  K   E     +E EE E+ K+   KK+       
Sbjct: 236 EEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKI------- 288

Query: 481 TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540
            D+R ++           E+EE         K + + +++    E++ +RE+E+    E 
Sbjct: 289 ADERARI-----------EAEE---------KAAAQERERREAEERERMREEEKRAAEER 328

Query: 541 KPSDAESSESSDDEKAWVEEVRK---QRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKA 597
           +    E   ++++ +   EE ++   +R+ +++EEK   +ER +   +   K +  E K 
Sbjct: 329 QRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKR 388

Query: 598 GEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQ---K 654
            ++    K +  + K+  + +E +++ +  N   +  D     K  T  LK+  ++   K
Sbjct: 389 NKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQED-----KLQTAVLKKQGEEKGTK 443

Query: 655 KQQEAEKLHRQE 666
            Q + EKL   +
Sbjct: 444 VQAKREKLQEDK 455



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 61/298 (20%), Positives = 117/298 (39%), Gaps = 38/298 (12%)

Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEE--EEEKQKSTWKKKVKSLPNI 479
           EE  +++ R+  +E   Q+ + + L +V  ++ +       +EE + +T   +V+     
Sbjct: 35  EEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEA 94

Query: 480 LTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKIS------------------EKRKKKL 521
              +R     E    ++ E  E  +  +P ++  S                  EK +K  
Sbjct: 95  AFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSE 154

Query: 522 RLLEQQELREKEEEEEPEGKPS--DAESSESSDDEKAWVEEVRKQRRLLQQEE-KVKRQE 578
              E+ E+ E E   +   K    DAE ++  D EK   EE + +R  + + + +V  +E
Sbjct: 155 SRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEE 214

Query: 579 RLKEDQQTVLKPQFY-------EIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTL 631
           +  E Q+  +            E K  EE     D  +  + M +  ED+ + EA+   L
Sbjct: 215 KTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEE--EDKERAEAERARL 272

Query: 632 SVSDT----TVGSKQLTFTLKRSEQQKKQ--QEAEKLHRQERKRLRRSAGHLKSRHKR 683
              +         K++     R E ++K   QE E+   +ER+R+R          +R
Sbjct: 273 EAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQR 330



 Score = 37.4 bits (85), Expect = 0.047
 Identities = 37/173 (21%), Positives = 78/173 (45%), Gaps = 29/173 (16%)

Query: 497 DEESEEFRLLNPL-------VSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSE 549
           + ESEEF  L          + ++ +KR+++ ++LE++E R K+EE         A+   
Sbjct: 545 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE---------ADRKL 595

Query: 550 SSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLK---PQFYEIKAGEEFRSFKD 606
             ++EK  ++E  ++RR    E++ K  E    D +   K   P+   +K  E       
Sbjct: 596 REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEE------- 648

Query: 607 SATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA 659
              + + +NK+++    +++ +    VS      +Q T  ++ ++  K  + A
Sbjct: 649 ---RAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPA 698



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 35/184 (19%), Positives = 83/184 (45%), Gaps = 31/184 (16%)

Query: 516 KRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVK 575
           +R+++LR  +++E+R + E               + DDE+   E  R++RR  +QE   +
Sbjct: 5   ERRRELRRQKREEMRLEAER---------IAYQRNDDDEE---EAARERRRRARQERLRQ 52

Query: 576 RQERLK----------------EDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLE 619
           +QE                    D++        +++  +E    +  A +++   K L+
Sbjct: 53  KQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQ 112

Query: 620 DRLKIEAK-NGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLK 678
           + L+ + + + T++ +  ++ S+++      +E  +K++++E   RQER  +  +    K
Sbjct: 113 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSES--RQERYEIEETETVTK 170

Query: 679 SRHK 682
           S  K
Sbjct: 171 SYQK 174



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 35/150 (23%), Positives = 72/150 (48%), Gaps = 6/150 (4%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLP-NILTDD 483
           ++++ R+ +EE   +R Q +   K+ +E   + ++EE E++++   +K + +P + L+DD
Sbjct: 571 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDD 630

Query: 484 R--FKVMFENPDFQVDEESEEFRLLNPLVSKIS-EKRKKKLRLLEQQELREKEEEEEPEG 540
           +  FK           EE  EF  LN  V K S  K   +  ++ + + R ++     EG
Sbjct: 631 KKPFKCFTPKGSSLKIEERAEF--LNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEG 688

Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQ 570
             S   +  ++ D     E VR  + + ++
Sbjct: 689 TKSAKPTKPAASDLPVPAEGVRNIKSMWEK 718


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 59/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQK------STWKKKVKSLPN 478
           R++++R K+ + R +  Q+K+  K   E     I+E+ EK K         KKK  +   
Sbjct: 574 REERLR-KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 632

Query: 479 ILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKL-------RLLEQQELRE 531
              + R K   E    +  ++ EE R    L+ K  E+ +++L       RL EQ+E   
Sbjct: 633 EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 692

Query: 532 KEEE-EEPEGKPSDAESSESSDDEKAWVE-EVRKQRRLLQQEEKVKRQERLKEDQQTVLK 589
           +E+E  E E +  +    E  + E+   E E R+++  LQ E +++ +E+    Q+  L+
Sbjct: 693 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 752

Query: 590 PQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLT 644
            +  E K  EE +   +   +++   K  E     +A N T+ V      S Q+T
Sbjct: 753 RELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMT 807



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 56/259 (21%), Positives = 113/259 (43%), Gaps = 51/259 (19%)

Query: 430 RQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMF 489
           RQK+EE + +R++  KL +  +   +    E  E+ K   KK++                
Sbjct: 556 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI---------------- 599

Query: 490 ENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSE 549
           E    Q+DE++E+ +     +++   K+K   + +E+ E R K+E               
Sbjct: 600 EQKFAQIDEKTEKAK--EERLAEEKAKKKAAAKKMEEVEARRKQE--------------- 642

Query: 550 SSDDEKAWVEEVRKQRRLLQQEEKVKRQERL---KEDQQTVLKPQFYEIKAGEEFRSFKD 606
                    EE R+ R L Q+EE+ + QE L   KE++Q  L+      KA E  R  + 
Sbjct: 643 ---------EEARRLRWLQQEEEERRHQELLQKKKEEEQERLR------KAAEAKRLAEQ 687

Query: 607 SATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQE 666
              +++   +  ++R + E +       +  +  ++     +R + +++ QE EK  R +
Sbjct: 688 REQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 747

Query: 667 RKRLRRSAGHLKSRHKRGR 685
           +++L+R     K + ++ R
Sbjct: 748 KEQLQRELEEKKKKEEQQR 766


>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
           sapiens]
          Length = 551

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 61/259 (23%), Positives = 119/259 (45%), Gaps = 44/259 (16%)

Query: 426 KDKIRQKIEETRAQRVQLKKLPKVNKELALKLIE-------EEEEKQKSTWKKKVKSLPN 478
           + KI ++ E       +L  L +V KE A  L++       E+EE+ K   K  + +  +
Sbjct: 145 RKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIILNAKCH 204

Query: 479 ILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEP 538
            + D +   + E    Q + ++EE RL      ++ E  ++K  +  Q+EL  K  EE  
Sbjct: 205 AIRDAQ---ILEKQQIQKELDTEEKRL-----DQMMEVERQK-SIQRQEELERKRREERI 255

Query: 539 EGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERL-KEDQQTVLKPQFYEIKA 597
            G+    E  E + +E++ + E R+Q    ++E+ ++  E+L +ED + + + Q  ++K 
Sbjct: 256 RGRRQIVEQMEKNQEERSLLAEQREQ----EKEQMLEYMEQLQEEDLKDMERRQQQKLKM 311

Query: 598 GEEFRSFKDSATKQK---LMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQK 654
             E +   D   KQK   L  + L D++ +E                   FT K+  ++ 
Sbjct: 312 QAEIKRINDENQKQKAELLAQEKLADQMVME-------------------FTKKKMAREA 352

Query: 655 K-QQEAEKLHRQERKRLRR 672
           + + E E++ R++ K + R
Sbjct: 353 EFEAEQERIRREKEKEIAR 371



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 43/250 (17%), Positives = 107/250 (42%), Gaps = 28/250 (11%)

Query: 431 QKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFE 490
           ++++E   + ++ ++  K+  +  +K I +E +KQK+    + K    ++ +   K M  
Sbjct: 291 EQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAR 350

Query: 491 NPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSES 550
             +F+ ++E                +R+K+  +   + ++EK ++ + E     A+ ++ 
Sbjct: 351 EAEFEAEQERI--------------RREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQE 396

Query: 551 SDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKD--SA 608
             D + W  + ++  R   + E   R+ RL   +Q   K     ++   +   F+    A
Sbjct: 397 VAD-REWRRKEKENARKKMETEAELRKSRL---EQVAFKEHALAVQVQRDRDEFERILRA 452

Query: 609 TKQKLMNKTLEDRLKI--------EAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAE 660
            ++++  + LE+  K         E +          V ++  TF   R  +++ Q+  E
Sbjct: 453 QREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRE 512

Query: 661 KLHRQERKRL 670
           ++   +RK+L
Sbjct: 513 RIDEIKRKKL 522



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 41/191 (21%), Positives = 85/191 (44%), Gaps = 46/191 (24%)

Query: 515 EKRKKKLRLLEQQELREKEEEEEPEGKPS-DAESSESS---DDEKAW--------VEEVR 562
           E+ K    +L ++EL  +++  + E + + DA  +        E  W        +EEV 
Sbjct: 110 ERIKWASHVLTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVA 169

Query: 563 KQR--RLLQQEEKVK--RQERLKEDQQTVLKPQFYEIKAG---EEFRSFKDSATKQKLMN 615
           K+R   LLQ+  K++  ++E LK+  + +L  + + I+     E+ +  K+  T++K ++
Sbjct: 170 KERAQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLD 229

Query: 616 KTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAG 675
           + +E                           ++R +  ++Q+E E+  R+ER R RR   
Sbjct: 230 QMME---------------------------VERQKSIQRQEELERKRREERIRGRRQIV 262

Query: 676 HLKSRHKRGRS 686
               +++  RS
Sbjct: 263 EQMEKNQEERS 273


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 54/261 (20%), Positives = 122/261 (46%), Gaps = 32/261 (12%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEE--KQKSTWKKKVKSLPNILTD 482
           ++ ++R++  + R Q  Q+++      E   ++ E+EE+  +Q+   +K+ + +     +
Sbjct: 169 QEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE--QE 226

Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542
           ++ +   E    Q+ E+ E+ +     V K  E+ +K+   + +QE + +E+EE+   + 
Sbjct: 227 EQMRKQEE----QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282

Query: 543 SDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQE---RLKEDQQTVLKPQFYEIKAGE 599
              E  E + +++  + E  +Q R  +QEE+++ QE   R +E+Q    + Q +E K  E
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMR--EQEEQMREQEEQMREQEEQMGKQEEQMWEQK--E 338

Query: 600 EFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA 659
           +    K+   KQ+      E++++                 KQ     K+ EQ +KQ+E 
Sbjct: 339 QMWEQKEQMWKQEEQMGEQEEQMQ-----------------KQEEQVRKQEEQMRKQEEQ 381

Query: 660 EKLHRQERKRLRRSAGHLKSR 680
            +   ++ ++     G  K +
Sbjct: 382 MRKQEEQMRKQEEQMGEQKEQ 402



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 38/180 (21%), Positives = 95/180 (52%), Gaps = 7/180 (3%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEE--KQKSTWKKKVKSLPNILTD 482
           ++++++++ E+ + Q  Q++K  +  +E   ++ E+EE+  KQK   +++ ++       
Sbjct: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298

Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKR-KKKLRLLEQQELREKEEEEEPEGK 541
              +      + Q+ E+ E+ R     + K  E+  ++K ++ EQ+E   K+EE+  E  
Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE-- 356

Query: 542 PSDAESSESSDDEKAWVEEVRKQR-RLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600
             + +  +  +  +   E++RKQ  ++ +QEE++++QE    +Q+  +  Q  +++  EE
Sbjct: 357 -QEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEE 415



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 50/257 (19%), Positives = 124/257 (48%), Gaps = 19/257 (7%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEE-----EEKQKSTWKKKVKSLPNI 479
           ++ ++R++  + R Q  Q+++     +E   ++ E+E     +E Q    + +V+     
Sbjct: 71  QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 130

Query: 480 LTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE---E 536
           + +   +V     + QV E+  + R     V +   + +++   + +QE + +E+E    
Sbjct: 131 VREQEGQV--REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188

Query: 537 EPEGKPSDAESSESSDDEKAWVEEVRKQRR---LLQQEEKV-KRQERLKEDQQTVLKPQF 592
           E EG+  + E      +E+   +E + Q++   + +QEE++ K++E++ E ++ V K + 
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248

Query: 593 YEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQ 652
              K  E+ R  ++   +Q+   +  E+++ ++ K  T     T    +Q    ++  E+
Sbjct: 249 QVQKQEEQMRKQEEQMREQEEQMREQEEQM-LKQKEQTEQEEQTGEQEEQ----MREQEE 303

Query: 653 QKKQQEAEKLHRQERKR 669
           Q ++QE +   ++E+ R
Sbjct: 304 QMREQEEQMREQEEQMR 320



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 32/164 (19%), Positives = 84/164 (51%), Gaps = 32/164 (19%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE---EKQKSTWKKKVKSLPNILT 481
           +++++R++ E+ R Q  Q+++  +  +E   ++ ++EE   E+++  W++K +       
Sbjct: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ------- 346

Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541
                 M++  + Q+ E+ E+            +K+++++R  +Q+E   K+EE+  + +
Sbjct: 347 ------MWKQEE-QMGEQEEQM-----------QKQEEQVR--KQEEQMRKQEEQMRKQE 386

Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQ 585
               +  E   ++K  + E ++Q R  +QEE++  Q+     Q+
Sbjct: 387 EQMRKQEEQMGEQKEQMGEQKEQMR--EQEEQMGEQKEQMRKQE 428



 Score = 33.5 bits (75), Expect = 0.67
 Identities = 32/163 (19%), Positives = 75/163 (46%), Gaps = 7/163 (4%)

Query: 524 LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED 583
           +  +EL+EK  E + E +  + E SE     K    ++   +  L QE +V+ QE    +
Sbjct: 4   ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVRE 63

Query: 584 QQTVLKPQFYEIKAGE-EFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQ 642
           Q+  ++ Q  +++  E + R  +    +Q+   +  E   ++  + G +   +  V  ++
Sbjct: 64  QEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQV--RE 119

Query: 643 LTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
               ++  E Q ++QE +   R++  ++R   G ++ +  + R
Sbjct: 120 QEGQVREQEGQVREQEGQV--REQEGQVREQEGQVREQEGQVR 160


>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
          Length = 1460

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 59/277 (21%), Positives = 135/277 (48%), Gaps = 24/277 (8%)

Query: 431 QKIEETRAQRVQLKKLPKVNKEL-ALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMF 489
           Q+  E   ++V +   P V+ E+ + + +   E+  ++  K   +++  +L  D+  ++ 
Sbjct: 553 QEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLE 612

Query: 490 ENPDFQV--------DEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEP-EG 540
              +           +EE E  RL       +S  R++  + +E++E R +EEE +    
Sbjct: 613 SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW 672

Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQER--LKEDQQTVLKPQFYEIKAG 598
             +  +SS  +D+++   E+    ++L ++ E  ++ ER  L++  + +L+    EI+A 
Sbjct: 673 LRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEAS 732

Query: 599 EEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSV-SDTTVGSKQLTFTLKR------SE 651
           E+      +A K+K + + L ++L+ E K    ++  + +   ++L  +L+       S 
Sbjct: 733 EKSEQAALNAAKEKALQQ-LREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSS 791

Query: 652 QQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGRSFH 688
            QKK QEA+   ++E  +L++  G ++ R  + +S+H
Sbjct: 792 LQKKIQEAQ---QKEEAQLQKCLGQVEHRVHQ-KSYH 824



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 59/298 (19%), Positives = 125/298 (41%), Gaps = 47/298 (15%)

Query: 422 EEYRKDKIRQKI---EETRAQRVQLKKLPKVN--KELALKLIEEEE------EKQKSTWK 470
           ++ +  ++R+K+   EE    R+  +K   ++  +E   K IEEEE      E Q+ +W 
Sbjct: 614 KQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWL 673

Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQ-EL 529
           +          +D+ +   E    ++ EE E  +      + + +K ++ L  L+++ E 
Sbjct: 674 RAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAER--ASLEQKNRQMLEQLKEEIEA 731

Query: 530 REKEEE---------------EEPEGKPSDA----ESSESSDDEKAWVEEVRKQRRLLQQ 570
            EK E+               E+ EG+  +A    E   S++ E+       K R ++  
Sbjct: 732 SEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSS 791

Query: 571 EEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGT 630
            +K  ++ + KE+ Q  L+    +++     +S+  +  + +L +   E R ++E ++  
Sbjct: 792 LQKKIQEAQQKEEAQ--LQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEH-- 847

Query: 631 LSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGRSFH 688
                     ++    +K   QQ   +  E+   +ERK+     GHL    +R +  H
Sbjct: 848 ----------ERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAH 895



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 53/253 (20%), Positives = 115/253 (45%), Gaps = 50/253 (19%)

Query: 420  AYEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNI 479
            A E+Y  ++ +Q+ E       +L++L + + E  L+ + +E+ K+    +++ +     
Sbjct: 865  AREQYEAEERKQRAELLGHLTGELERLQRAH-ERELETVRQEQHKRLEDLRRRHREQERK 923

Query: 480  LTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLE-QQELREKEEEEEP 538
            L D            ++D E+             ++  K +L LLE Q+E   +E+++  
Sbjct: 924  LQD-----------LELDLETR------------AKDVKARLALLEVQEETARREKQQLL 960

Query: 539  EGKPSDAESSESSDDEKAWVEEVRKQR-RLLQQEEKVK------RQERLK-EDQQTVLKP 590
            + +   A  SE +      +EE +K+   LLQ  ++++      +  +LK E Q  +L+ 
Sbjct: 961  DVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQA 1020

Query: 591  QFYEIKAGEEFRSFKDSATKQK--LMNKTLEDR---------LKIEAKNGTLSVSDTTVG 639
            Q  +++  + F S +  A K++  L   T+E+          L IE    +L  + T   
Sbjct: 1021 QSQQLQ--KHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQT--- 1075

Query: 640  SKQLTFTLKRSEQ 652
             K+++ +L +S++
Sbjct: 1076 -KEVSSSLSQSKE 1087



 Score = 30.4 bits (67), Expect = 5.7
 Identities = 33/145 (22%), Positives = 57/145 (39%), Gaps = 3/145 (2%)

Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVE-EVRKQRRLLQQEEKVKRQERLKEDQQTVLK 589
           E+E  + PEG+P   E+ E  +D  A +  ++  QR           + + +  Q   L 
Sbjct: 491 EEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELG 550

Query: 590 PQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGS--KQLTFTL 647
           P   E +  EE  +   +      +  T       +     L   +  V    +Q    L
Sbjct: 551 PGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHL 610

Query: 648 KRSEQQKKQQEAEKLHRQERKRLRR 672
             S+Q+K QQ  EKL ++E + + R
Sbjct: 611 LESKQEKMQQLREKLCQEEEEEILR 635


>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 238

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 51/203 (25%), Positives = 101/203 (49%), Gaps = 24/203 (11%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE----------EKQKSTWKKKVK 474
           R+ K+R++ E  R Q  ++++  +  +E   K+ E+EE          E+++  W+++ K
Sbjct: 10  REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEK 69

Query: 475 SLPNILTDDRFKVMFENPDFQVDEESEEFR--LLNPLVSKISEKRKKKLRLLEQQELREK 532
                   ++ + M+E  D ++ E+ E  R   +   V K+ EK+K +   +++QE + +
Sbjct: 70  MWEQQRLPEQKEKMWEQ-DERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128

Query: 533 EEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQF 592
           E+EE       + E      +EK W +E     ++ +QEEK++ QE   + Q+   K + 
Sbjct: 129 EQEE----MMWEQEEKMQEQEEKMWEQE----EKMREQEEKMREQEEKMQGQEE--KMRD 178

Query: 593 YEIKAGEEFR-SFKDSATKQKLM 614
            E   GE    S +D+ T Q++M
Sbjct: 179 VEPAGGEAGEGSPQDNPTAQEIM 201



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 36/176 (20%), Positives = 83/176 (47%), Gaps = 6/176 (3%)

Query: 516 KRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQ---RRLLQQEE 572
           + ++++R  E++   E+E   E E K  + E      +EK W +E + Q    ++ +QEE
Sbjct: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61

Query: 573 KVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLS 632
           K+  QE    +QQ + + +    +  E  R  ++   +QK+  +  + R K + +   + 
Sbjct: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121

Query: 633 VSDTTVGSKQLTF---TLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685
             +  +  ++        K  EQ++K  E E+  R++ +++R     ++ + ++ R
Sbjct: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 49/181 (27%), Positives = 83/181 (45%), Gaps = 11/181 (6%)

Query: 512 KISEKRKKKLRLLEQQELREKEEEEEPE-GKPSDAESSESSDDEKAWVEEVRKQRRLLQQ 570
           KI EK + K +  E++  REKE E+E E GK  D +     D EK   ++  ++R    +
Sbjct: 383 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 442

Query: 571 EEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGT 630
           +++ K +E+ ++ ++   K +  EI   E+ +  K S T  +  N +   R     +   
Sbjct: 443 KDRDKEKEKEQDKEKEREKDRSKEI--DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 500

Query: 631 LSVSDT-------TVGSKQLTFTLKRSEQQK-KQQEAEKLHRQERKRLRRSAGHLKSRHK 682
            S S +       T+  K       RS  +K K++E E+ H  ER+   RS    KS + 
Sbjct: 501 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 560

Query: 683 R 683
           R
Sbjct: 561 R 561



 Score = 33.1 bits (74), Expect = 0.88
 Identities = 35/166 (21%), Positives = 60/166 (36%), Gaps = 21/166 (12%)

Query: 511 SKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQR----- 565
           SK     K   R    Q             +  D   S+S   +++   E RK R     
Sbjct: 314 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 373

Query: 566 --RLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLK 623
             +     EK+K +ER+KE             K  E+ R  +    K+K   K  +DR K
Sbjct: 374 RDKRKDTREKIKEKERVKE-------------KDREKEREREKEREKEKERGKN-KDRDK 419

Query: 624 IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKR 669
              K+            ++      R ++++K+Q+ EK   ++R +
Sbjct: 420 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 465


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 49/181 (27%), Positives = 83/181 (45%), Gaps = 11/181 (6%)

Query: 512 KISEKRKKKLRLLEQQELREKEEEEEPE-GKPSDAESSESSDDEKAWVEEVRKQRRLLQQ 570
           KI EK + K +  E++  REKE E+E E GK  D +     D EK   ++  ++R    +
Sbjct: 267 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 326

Query: 571 EEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGT 630
           +++ K +E+ ++ ++   K +  EI   E+ +  K S T  +  N +   R     +   
Sbjct: 327 KDRDKEKEKEQDKEKEREKDRSKEI--DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 384

Query: 631 LSVSDT-------TVGSKQLTFTLKRSEQQK-KQQEAEKLHRQERKRLRRSAGHLKSRHK 682
            S S +       T+  K       RS  +K K++E E+ H  ER+   RS    KS + 
Sbjct: 385 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 444

Query: 683 R 683
           R
Sbjct: 445 R 445



 Score = 33.1 bits (74), Expect = 0.88
 Identities = 35/166 (21%), Positives = 60/166 (36%), Gaps = 21/166 (12%)

Query: 511 SKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQR----- 565
           SK     K   R    Q             +  D   S+S   +++   E RK R     
Sbjct: 198 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 257

Query: 566 --RLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLK 623
             +     EK+K +ER+KE             K  E+ R  +    K+K   K  +DR K
Sbjct: 258 RDKRKDTREKIKEKERVKE-------------KDREKEREREKEREKEKERGKN-KDRDK 303

Query: 624 IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKR 669
              K+            ++      R ++++K+Q+ EK   ++R +
Sbjct: 304 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 349


>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
          Length = 514

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 62/252 (24%), Positives = 113/252 (44%), Gaps = 22/252 (8%)

Query: 433 IEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENP 492
           IEE R +  +L  L +      ++L +E  E++K   ++K K L      +R   + E  
Sbjct: 94  IEERRNKLRELLALEENEYFTEMQLKKETIEEKKDRMREKTKLLKEKNEKERQDFVAEKL 153

Query: 493 DFQVDEESEEFR--LLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSES 550
           D Q  E  EE R  LL+    K+ E+RK ++   E+   R+K  EE+   K  + +    
Sbjct: 154 DQQFRERCEELRVELLSIHQKKVCEERKAQIAFNEELS-RQKLVEEQMFSKLWEEDRLAK 212

Query: 551 SDDEKAWVEEVRKQRRLLQQEE----------KVKRQ--ERLKEDQQTVLKPQFYEIKAG 598
              EK   +E R+Q+ L++             K +RQ  + LKE++  +++    +IK  
Sbjct: 213 ---EKREAQEARRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLVESNNAQIKHE 269

Query: 599 EEFRSFKDSATKQK---LMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655
            E    K    KQ+   ++ K L++R++   +       D  +   Q      + E  KK
Sbjct: 270 NEQDMLKKQKAKQETRTILQKALQERIE-HIQQEYRDEQDLNMKLVQRALQDLQEEADKK 328

Query: 656 QQEAEKLHRQER 667
           +Q+ E + R+++
Sbjct: 329 KQKREDMIREQK 340



 Score = 33.1 bits (74), Expect = 0.88
 Identities = 62/278 (22%), Positives = 112/278 (40%), Gaps = 66/278 (23%)

Query: 429 IRQKIEETRAQRVQLKKLPKVNKELALKLIE------EEEEKQKSTWKKKVKSLPNILTD 482
           +  +I   +AQR   + L    KE   +L+E      + E +Q    K+K K     +  
Sbjct: 234 LNAQITSIKAQRQATQLL----KEEEARLVESNNAQIKHENEQDMLKKQKAKQETRTILQ 289

Query: 483 DRFKVMFENPDFQVDEESE-----EFRLLNPLVSKISEKRKKKLRLLEQQE-----LREK 532
              +   E+   +  +E +       R L  L  +  +K++K+  ++ +Q+     L ++
Sbjct: 290 KALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQR 349

Query: 533 EEEEEPEGKPSD-------AESSESSDDE--------KAWVEEVRKQRRLLQQEEKVKRQ 577
            EEE+ + K  D       A+     D E        +  V+EV   R+ LQ +EK++R+
Sbjct: 350 REEEKAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVMCTRK-LQVQEKLQRE 408

Query: 578 ERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTT 637
            + +E++                       A +QK +N++L++    E +N         
Sbjct: 409 AKEQEER-----------------------AMEQKHINESLKELNCEEKENFARRQRLAQ 445

Query: 638 VGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAG 675
              KQL   +     Q++ QEAEK    E KR    AG
Sbjct: 446 EYRKQLQMQI---AYQQQSQEAEK----EEKRREFEAG 476


>gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1
           [Homo sapiens]
          Length = 621

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 55/236 (23%), Positives = 108/236 (45%), Gaps = 41/236 (17%)

Query: 460 EEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVS-------- 511
           +EEEK+K+  +           D+R  +  +N   +   + EE   +  LV         
Sbjct: 231 DEEEKEKAECR-----------DERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPR 279

Query: 512 ----KISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRL 567
               K  EK KK+     + E + KE+E + + + ++ E++  + +++   EEVR+Q  L
Sbjct: 280 IKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEE--EEVRQQALL 337

Query: 568 LQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLE---DRLK- 623
            ++E+ ++++   KE Q+           + + +  F D+  ++  M + +E   DRL+ 
Sbjct: 338 AKKEKDIQKKAIKKERQKL--------RNSCKTWNHFSDNEAERVKMMEEVEKLCDRLEL 389

Query: 624 --IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQ--KKQQEAEKLHRQERKRLRRSAG 675
             ++  N TL+     VG   L   ++   +Q  K+++EAE   RQ  K   +S G
Sbjct: 390 ASLQCLNETLTSCTKEVGKAALEKQIEEINEQIRKEKEEAEARMRQASKNTEKSTG 445


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 46/186 (24%), Positives = 96/186 (51%), Gaps = 13/186 (6%)

Query: 495 QVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE---EPEGKPSDAESSESS 551
           Q+  E E  ++L+ L  +  E+ +++   L +QE R +E+EE   E E +  + E     
Sbjct: 179 QLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLRE 238

Query: 552 DDEKAWVEEVR---KQRRLLQQEEKV-KRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDS 607
            +E+   +E R    + RL +QEE++ +++ERL+E ++ + + +    +  E  R  ++ 
Sbjct: 239 QEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEER 298

Query: 608 ATKQKLMNKTLEDRL-----KIEAKNGTLSVSDTTVGSKQLTFTL-KRSEQQKKQQEAEK 661
             +Q+   +  E+RL     ++  +   L   +   G ++L   + K  EQ+++Q+E E+
Sbjct: 299 LCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQER 358

Query: 662 LHRQER 667
           L  +ER
Sbjct: 359 LLERER 364



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 42/170 (24%), Positives = 80/170 (47%), Gaps = 13/170 (7%)

Query: 430 RQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMF 489
           R++ E  R Q  +L++  +  +E   +L E+EE  ++   + + +       ++R +   
Sbjct: 195 RRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHE 254

Query: 490 ENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE-LREKEEE---------EEPE 539
           E    Q +   E+   L     ++ E+ +   RL EQ+E LRE+EE          E+ E
Sbjct: 255 ERLCEQEERLCEQEERLREQEERLHEQEE---RLCEQEERLREQEERLCEQEERLREQEE 311

Query: 540 GKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLK 589
                 E     ++     E++  Q RLL++ EK+  QER +E+Q+ +L+
Sbjct: 312 RLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLE 361



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 54/230 (23%), Positives = 108/230 (46%), Gaps = 33/230 (14%)

Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEE--KQKSTWKKKVKSLPNILTD 482
           +++++R++ E  R Q  +L +  +  +E   +L E+EE   +Q+   +++ + L     +
Sbjct: 225 QEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHE--QE 282

Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEK----RKKKLRLLEQQEL-------RE 531
           +R     E    Q +   E+   L     ++ E+    R+++ RL EQ++L        E
Sbjct: 283 ERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEE 342

Query: 532 KEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV------KRQERLKEDQQ 585
            E+  E E +  + E     +     VEE+ +Q RL QQ+E++      +  ERL+E ++
Sbjct: 343 VEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELER 402

Query: 586 TV------LKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNG 629
            +      L  Q  E ++G E  + ++ +T Q      LE ++K   K+G
Sbjct: 403 MLELGWEALYEQRAEPRSGFEELNNENKSTLQ------LEQQVKELKKSG 446



 Score = 34.7 bits (78), Expect = 0.30
 Identities = 37/159 (23%), Positives = 73/159 (45%), Gaps = 24/159 (15%)

Query: 526 QQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQE-RLKEDQ 584
           Q E     +E E  G+   AE     +++   +   R++ RL +QEE+++ QE RL+E +
Sbjct: 163 QDETNHLRKELESVGRQLQAEVE---NNQMLSLLNRRQEERLREQEERLREQEERLREQE 219

Query: 585 QTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLT 644
           + + + +    +  E  R  ++   +Q+   +  E+RL  + +                 
Sbjct: 220 ERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEER---------------- 263

Query: 645 FTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683
             L   E++ ++QE E+LH QE +RL      L+ + +R
Sbjct: 264 --LCEQEERLREQE-ERLHEQE-ERLCEQEERLREQEER 298


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,545,100
Number of Sequences: 37866
Number of extensions: 1226863
Number of successful extensions: 20195
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 298
Number of HSP's successfully gapped in prelim test: 1021
Number of HSP's that attempted gapping in prelim test: 9614
Number of HSP's gapped (non-prelim): 5695
length of query: 688
length of database: 18,247,518
effective HSP length: 109
effective length of query: 579
effective length of database: 14,120,124
effective search space: 8175551796
effective search space used: 8175551796
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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