BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|171460958 nucleolar protein 10 [Homo sapiens] (688 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|171460958 nucleolar protein 10 [Homo sapiens] 1377 0.0 gi|148746195 trichohyalin [Homo sapiens] 67 5e-11 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 65 2e-10 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 65 2e-10 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 62 1e-09 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 62 2e-09 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 2e-09 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 62 2e-09 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 61 3e-09 gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 61 3e-09 gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 61 3e-09 gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 61 3e-09 gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 61 3e-09 gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 60 7e-09 gi|221219020 NYD-SP11 protein [Homo sapiens] 59 1e-08 gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 59 1e-08 gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 59 1e-08 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 58 3e-08 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 58 3e-08 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 57 6e-08 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 57 7e-08 gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 56 1e-07 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 55 2e-07 gi|115648142 centrosomal protein 164kDa [Homo sapiens] 55 2e-07 gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 55 2e-07 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 55 2e-07 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 55 2e-07 gi|94721321 coiled-coil domain containing 11 [Homo sapiens] 54 4e-07 gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ... 54 5e-07 gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 54 6e-07 >gi|171460958 nucleolar protein 10 [Homo sapiens] Length = 688 Score = 1377 bits (3565), Expect = 0.0 Identities = 688/688 (100%), Positives = 688/688 (100%) Query: 1 MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKV 60 MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKV Sbjct: 1 MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKV 60 Query: 61 SKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIE 120 SKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIE Sbjct: 61 SKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIE 120 Query: 121 FHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENN 180 FHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENN Sbjct: 121 FHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENN 180 Query: 181 VCDINSVHGLFATGTIEGRVECWDPRTRNRVGLLDCALNSVTADSEINSLPTISALKFNG 240 VCDINSVHGLFATGTIEGRVECWDPRTRNRVGLLDCALNSVTADSEINSLPTISALKFNG Sbjct: 181 VCDINSVHGLFATGTIEGRVECWDPRTRNRVGLLDCALNSVTADSEINSLPTISALKFNG 240 Query: 241 ALTMAVGTTTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLDLILSADSRIVKMWNK 300 ALTMAVGTTTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLDLILSADSRIVKMWNK Sbjct: 241 ALTMAVGTTTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLDLILSADSRIVKMWNK 300 Query: 301 NSGKIFTSLEPEHDLNDVCLYPNSGMLLTANETPKMGIYYIPVLGPAPRWCSFLDNLTEE 360 NSGKIFTSLEPEHDLNDVCLYPNSGMLLTANETPKMGIYYIPVLGPAPRWCSFLDNLTEE Sbjct: 301 NSGKIFTSLEPEHDLNDVCLYPNSGMLLTANETPKMGIYYIPVLGPAPRWCSFLDNLTEE 360 Query: 361 LEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFA 420 LEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFA Sbjct: 361 LEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFA 420 Query: 421 YEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL 480 YEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL Sbjct: 421 YEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL 480 Query: 481 TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540 TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG Sbjct: 481 TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540 Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE Sbjct: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600 Query: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAE 660 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAE Sbjct: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAE 660 Query: 661 KLHRQERKRLRRSAGHLKSRHKRGRSFH 688 KLHRQERKRLRRSAGHLKSRHKRGRSFH Sbjct: 661 KLHRQERKRLRRSAGHLKSRHKRGRSFH 688 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 67.0 bits (162), Expect = 5e-11 Identities = 59/288 (20%), Positives = 125/288 (43%), Gaps = 37/288 (12%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 ++ R + Q++ + R ++ + ++ +E K EEE++ ++ ++K L Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR 1456 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541 +R + E + E ++ ++R +K EQQ R++ + + E + Sbjct: 1457 QERHRKFREEEQLLQEREEQQLH---------RQERDRKFLEEEQQLRRQERDRKFREQE 1507 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQER-----------LKEDQQTVLKP 590 E +E+ + ++QR+ LQ+E++++RQER +E++Q + Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567 Query: 591 QFYEIKAGEEFRSFK---DSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTL 647 + ++ E R F+ +Q+ K +ED ++ + G + ++ Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL------RQERDRKF 1621 Query: 648 KRSEQQKKQQEAEKLHRQERKR--------LRRSAGHLKSRHKRGRSF 687 + EQ +++E ++LHRQER R LRR + RH R R F Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669 Score = 63.9 bits (154), Expect = 5e-10 Identities = 64/296 (21%), Positives = 137/296 (46%), Gaps = 44/296 (14%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 EE+ ++ ++ E +R ++ + +E ++ +EEEEK+ W+K+ +L Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE---WRKR----ETVLR 254 Query: 482 DDRFKVMFENPDFQ--VDEESEEFRLLN--PLVSKISEKRKKKLRLLEQQELREKEEEEE 537 + K+ E P Q + EE E+ R L L + E+ +++ RL +Q+LR K+EEE Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314 Query: 538 PEGKPSDAESSESSDDE--------------------KAWVEEVRKQRRLLQQEEKVKRQ 577 E + E E + + + EE R++++L +++E+ +R+ Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374 Query: 578 ERLKEDQQTVLKPQF---YEIKAGEEFRSFKDSATKQKLMNK---TLEDRLKIEAKNGTL 631 ++L+ +QQ + Q +++ ++ R + +Q+L + E +L+ E + Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434 Query: 632 SVSDTTVGSKQLTFTLKRSEQQK----KQQEAEKLHRQERKRLRRSAGHLKSRHKR 683 +Q LKR ++++ K++E + H QER++ + + R +R Sbjct: 435 EQKHEQERREQ---RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487 Score = 63.9 bits (154), Expect = 5e-10 Identities = 57/265 (21%), Positives = 130/265 (49%), Gaps = 30/265 (11%) Query: 423 EYRKDKIRQKIEET-------RAQRVQLKKLPKVNKELALK----LIEEEEEKQKSTWKK 471 +YRKDK Q+ EE + +R + +K + +EL + L EE E++++ W++ Sbjct: 959 QYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018 Query: 472 KVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELRE 531 + + + ++ + E ++ E ++R L +++++ L E++E R Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEEL------QQEEEQLLGEERETRR 1072 Query: 532 KEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQ 591 ++E E K + + E E+ EE K+RR ++E + + +E L+++++ +L+ + Sbjct: 1073 RQELERQYRKEEELQQEE----EQLLREEPEKRRRQ-ERERQCREEEELQQEEEQLLREE 1127 Query: 592 FYEIKAGEEFRSFKD----SATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTL 647 + + E R +++ +++L+ + E R + E + + +QL Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL--- 1184 Query: 648 KRSEQQKKQQEAEKLHRQERKRLRR 672 R EQ+K++QE E+ +R+E + R+ Sbjct: 1185 -REEQEKRRQERERQYREEEELQRQ 1208 Score = 62.8 bits (151), Expect = 1e-09 Identities = 66/282 (23%), Positives = 133/282 (47%), Gaps = 46/282 (16%) Query: 422 EEYRKDKIRQKIEETRAQRVQ-LKKLPKVNKELALK---LIEEEEEKQKSTWKKKVKSLP 477 E+ R K R ++EE R +R L P + ++L + L EEEEE Q+ +K+ + Sbjct: 867 EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ-- 924 Query: 478 NILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLR---LLEQQELREKEE 534 ++ + E Q +EE L+ + EKR+++ R + ++L++KEE Sbjct: 925 -----EQERQYREEEQLQQEEEQ--------LLREEREKRRRQERERQYRKDKKLQQKEE 971 Query: 535 E---EEPEGKPSDA------ESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQ 585 + EEPE + E E +E+ + E R++RR + E + ++++ L+++++ Sbjct: 972 QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031 Query: 586 TVLKPQFYEIKAGEEFRSFKDSATKQK----LMNKTLEDRLKIEAKNGTLSVSDTTVGSK 641 +L+ + + + E R +++ Q+ L+ + E R + E + + Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE------ 1085 Query: 642 QLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683 L++ E+Q ++E EK RQER+R R L+ ++ Sbjct: 1086 -----LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122 Score = 61.2 bits (147), Expect = 3e-09 Identities = 61/267 (22%), Positives = 125/267 (46%), Gaps = 36/267 (13%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELA-----LKLIEEEEEKQKSTWKKKVKSL 476 +E R+D ++++ E R ++ + K+ K ++E LKL EEE +Q+ +++++ Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE 510 Query: 477 PNILTDDRFKVMFENP--------DFQVDEESEEFR--LLNPLVSKISEKRKKKLRLLEQ 526 + R K E + Q+ E EE R LL K E+ +++ RL + Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570 Query: 527 QELREKE--EEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQ 584 QE R + + EE + E +++ EEV + + ++E+++KR+E +E + Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERR 630 Query: 585 QTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLT 644 Q +LK + E + ++ R + +Q+L + E+RL+ K Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR---------------- 674 Query: 645 FTLKRSEQQKKQQEAEKLHRQERKRLR 671 + E++++Q+ AE+ Q R+R++ Sbjct: 675 ---EHEEERREQELAEEEQEQARERIK 698 Score = 59.3 bits (142), Expect = 1e-08 Identities = 75/300 (25%), Positives = 137/300 (45%), Gaps = 55/300 (18%) Query: 430 RQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTW-----------KKKVKSLPN 478 RQ+ EE R +R +L +E A + +EEE+++ TW ++++ + P Sbjct: 732 RQEQEEKRRRRES--ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPP 789 Query: 479 ILTDDRFKVMFENPD-----FQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKE 533 + ++ E F +EE +E R + +R+K+L+ LE++E ++ Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQR------RRQRREREKELQFLEEEEQLQRR 843 Query: 534 E-----EEEPEGKPSDAE---SSESSDDEK-AW-VEEVRKQRRLLQ------QEEKVKRQ 577 E +EE +G D E S E D+K W +EE RK+RR QE+ K Q Sbjct: 844 ERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903 Query: 578 ERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQK----LMNKTLEDRLKIEAKNGTLSV 633 + L+E+++ + + + + + E+ R +++ Q+ L+ + E R + E + Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD 963 Query: 634 SDTTVGSKQLTFT----LKRSEQQKK-------QQEAEKLHRQERKRLRRSAGHLKSRHK 682 +QL +R E++KK QQE E+L R+ER++ RR + R K Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023 Score = 59.3 bits (142), Expect = 1e-08 Identities = 54/271 (19%), Positives = 125/271 (46%), Gaps = 30/271 (11%) Query: 414 LMVNPFAYEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALK-----------LIEEEE 462 L P E+ RK++ + EE QR + +K + +E + L+ EE Sbjct: 889 LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREER 948 Query: 463 EKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLR 522 EK++ +++ L +++ E P+ + +E E+ + +++L+ Sbjct: 949 EKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK-----------KYREEEELQ 997 Query: 523 LLEQQELRE-KEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLK 581 E+Q LRE +E+ E + + E +E+ + E R++RRL ++E + + +E L+ Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057 Query: 582 EDQQTVLKPQFYEIKAGEEFRSFKD----SATKQKLMNKTLEDRLKIEAKNGTLSVSDTT 637 ++++ +L + + E R ++ +++L+ + E R + E + + Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117 Query: 638 VGSKQLTFTLKRSEQQKKQQEAEKLHRQERK 668 +QL L+ +++++QE E+ +R+E + Sbjct: 1118 QEEEQL---LREEREKRRRQELERQYREEEE 1145 Score = 58.5 bits (140), Expect = 2e-08 Identities = 56/278 (20%), Positives = 133/278 (47%), Gaps = 33/278 (11%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 EE R+ ++R++ EE R Q+++ ++ + ++ + EEE +Q+ +++++ + Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541 + + + ++ R L + +R+++LR +Q+LR ++EEE E K Sbjct: 392 EQQLR------------REQQLRREQQLRREQQLRREQQLR--REQQLRREQEEERHEQK 437 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGE-- 599 + E+ + K+ ++ E+ +R+++LK DQ+ + ++ +++ E Sbjct: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497 Query: 600 --------EFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSE 651 + R ++ +Q+L + E+RL+ ++ + +QL LKR E Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL---LKREE 554 Query: 652 QQKKQQE--AEKLHRQERKR----LRRSAGHLKSRHKR 683 +++ +QE ++L R++ +R L+R + R KR Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592 Score = 57.8 bits (138), Expect = 3e-08 Identities = 53/266 (19%), Positives = 126/266 (47%), Gaps = 23/266 (8%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484 R+++ +++ +E Q + KKL + ++L L EE E++++ +KK + + ++ Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQL---LGEEPEKRRRQEREKKYREEEELQQEEE 1001 Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEE-PEGKPS 543 + E + E ++R +K +L+ E+Q LRE+ E+ E + Sbjct: 1002 QLLREEREKRRRQEWERQYR------------KKDELQQEEEQLLREEREKRRLQERERQ 1049 Query: 544 DAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRS 603 E E +E+ + E R+ RR + E + +++E L+++++ +L+ + + + E R Sbjct: 1050 YREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQ 1109 Query: 604 FKDSATKQK----LMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA 659 ++ Q+ L+ + E R + E + + +QL L+ +++++QE Sbjct: 1110 CREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL---LREEPEKRRRQEL 1166 Query: 660 EKLHRQERKRLRRSAGHLKSRHKRGR 685 E+ +R+E + + L+ ++ R Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRR 1192 Score = 57.8 bits (138), Expect = 3e-08 Identities = 57/291 (19%), Positives = 126/291 (43%), Gaps = 37/291 (12%) Query: 423 EYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKS------L 476 +YR+++ Q+ EE + Q K+ + ++ EEEE Q+ K++ + L Sbjct: 1169 QYREEEELQQEEEQLLREEQEKRRQERERQY-----REEEELQRQKRKQRYRDEDQRSDL 1223 Query: 477 PNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE- 535 ++ + +N + E+E+FR L + + ++ LL +Q+ R++E+E Sbjct: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER 1283 Query: 536 ----------------EEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQER 579 E E K + +S ++++ EE ++RR + + K + +E+ Sbjct: 1284 RRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ 1343 Query: 580 LKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTL---EDRLKIEAKNGTLSVSDT 636 L ++++ ++ E R F++ + + + E RL+ + + + Sbjct: 1344 LLQEREE------QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ 1397 Query: 637 TVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGRSF 687 + ++ L++ +K ++E ++L RQER R R R +R R F Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF 1448 Score = 53.9 bits (128), Expect = 5e-07 Identities = 51/266 (19%), Positives = 126/266 (47%), Gaps = 21/266 (7%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 EE ++ + RQ+ E + + ++ +E A +L EEE+ Q+ +++ + Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR--- 870 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE----LREKEEEEE 537 D +++ +Q++EE + R + E+ +K+ +LL+++E E+E+ Sbjct: 871 DQKWR-------WQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923 Query: 538 PEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKA 597 E + E + +E+ + E R++RR ++E + ++ ++L++ ++ +L + + + Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983 Query: 598 GEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQ 657 E + +++ ++ + + E L+ E + + K L++ E+Q ++ Sbjct: 984 QEREKKYRE----EEELQQEEEQLLREEREKRRRQEWERQYRKKD---ELQQEEEQLLRE 1036 Query: 658 EAEKLHRQERKRLRRSAGHLKSRHKR 683 E EK QER+R R L+ ++ Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQ 1062 Score = 53.5 bits (127), Expect = 6e-07 Identities = 61/266 (22%), Positives = 124/266 (46%), Gaps = 38/266 (14%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVN----KELALKLIEEEEEKQKSTWKKKVKSLP 477 EE R+ +++++ EE QR++ +++ ++ +E LK E EEE+++ K + + Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642 Query: 478 NILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEE 537 + E + ++ E EE RL L + E+R+ +QEL E+E+E+ Sbjct: 643 R--QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR-------EQELAEEEQEQA 693 Query: 538 PEGKPS-------DAESSESSDDEKAWVEEVRK--QRRLLQQEEKVKRQERLKEDQQTVL 588 E S ES + K + ++ QRR +QEEK +R+E Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES--------- 744 Query: 589 KPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLK 648 E++ EE R+ + +++ + T + + + +++ G +S +Q L+ Sbjct: 745 -----ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLR 799 Query: 649 RSEQQKKQQE--AEKLHRQERKRLRR 672 E+Q+++Q E+ +++R+R RR Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRR 825 Score = 52.8 bits (125), Expect = 1e-06 Identities = 53/263 (20%), Positives = 118/263 (44%), Gaps = 30/263 (11%) Query: 419 FAYEEYRKDKIRQK-IEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLP 477 F +E R + +K +EE + Q ++ + +E L+ E +++++ +K Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK------ 1556 Query: 478 NILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRK-----KKLRLLE-QQELRE 531 +++ + E E +FRL V + ++RK ++LR E QQ+LR+ Sbjct: 1557 -FREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ 1615 Query: 532 KE-----EEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQT 586 + E+E+ + + + D K EE + +R+ +Q+ + R + +E++Q Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL 1675 Query: 587 VLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFT 646 + + + +++ E R F++ E +L+ + + + + ++L Sbjct: 1676 LQEGEEQQLRRQERDRKFREE-----------EQQLRRQERERKFLQEEQQLRRQELERK 1724 Query: 647 LKRSEQQKKQQEAEKLHRQERKR 669 + EQ +++ E E+L RQER R Sbjct: 1725 FREEEQLRQETEQEQLRRQERYR 1747 Score = 52.4 bits (124), Expect = 1e-06 Identities = 60/274 (21%), Positives = 132/274 (48%), Gaps = 35/274 (12%) Query: 422 EEYRKDKIRQ-KIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL 480 ++ R D+ R+ + EE Q + ++L + ++ K EEE++ ++ ++K L Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDR--KFREEEQQLRRQERERKFLQEEQQL 1716 Query: 481 TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540 + F + Q+ +E+E+ +L ++++ ++LE+++LR + EE++ Sbjct: 1717 RRQELERKFREEE-QLRQETEQEQL---------RRQERYRKILEEEQLRPEREEQQLRR 1766 Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED-QQTVLKPQFYEIKAGE 599 + D + E +E+ E +Q R + + K + +E+L+++ ++ L+PQ Sbjct: 1767 QERDRKFRE---EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQ-------- 1815 Query: 600 EFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSD--TTVGSKQLTFTLKRSEQQKKQQ 657 R K +++L + E RL+ E + T S++ L + E+QK++Q Sbjct: 1816 -QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ 1874 Query: 658 EAEK------LHRQERKRLR-RSAGHLKSRHKRG 684 E E+ + RQ+++ R R G +KS+ +G Sbjct: 1875 ERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKG 1908 Score = 51.6 bits (122), Expect = 2e-06 Identities = 61/283 (21%), Positives = 121/283 (42%), Gaps = 31/283 (10%) Query: 435 ETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTD-DRFKVMFENPD 493 E Q+ ++ K +E L E EE++++ +K + +L + + + + D Sbjct: 1300 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359 Query: 494 FQVDEES----EEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE-----------EP 538 + EE E+ R ++ + +++ L E+Q+LR +E E+ E Sbjct: 1360 RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREE 1419 Query: 539 EGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQER---LKEDQQTVLKPQFYEI 595 E + S E +E+ V ++R+ L++E++ RQER +E++Q + + + ++ Sbjct: 1420 EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ-LRQERHRKFREEEQLLQEREEQQL 1478 Query: 596 KAGEEFRSF---KDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQ 652 E R F + +Q+ K E L+ + + + +Q + EQ Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQ 1538 Query: 653 QKKQQEAEKLHRQERKRLRRSAGHLK--------SRHKRGRSF 687 Q ++QE + RQ+R R R L+ SR +R R F Sbjct: 1539 QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF 1581 Score = 51.2 bits (121), Expect = 3e-06 Identities = 54/269 (20%), Positives = 123/269 (45%), Gaps = 39/269 (14%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 E+ +++ Q++ R L++ P++ ++ E E++ + +K + +L Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQ-------EREQQLRHDRDRKFREEEQLLQ 1677 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRK--KKLRLLEQQELREKEEEEEPE 539 + E + E +FR + + +RK ++ + L +QEL K EEE Sbjct: 1678 EG------EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731 Query: 540 GKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQER---LKEDQQTVLKPQFYEIK 596 + ++ E + + +EE +Q R ++E++++RQER +E++Q + + +++ Sbjct: 1732 RQETEQEQLRRQERYRKILEE--EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLR 1789 Query: 597 AGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQ 656 + E R F++ +++L + E +L+ + ++G + E+Q + Sbjct: 1790 SQESDRKFRE---EEQLRQEREEQQLRPQQRDGKY----------------RWEEEQLQL 1830 Query: 657 QEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 +E E+ RQER R R+ ++ K R Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRR 1859 Score = 50.4 bits (119), Expect = 5e-06 Identities = 62/284 (21%), Positives = 127/284 (44%), Gaps = 46/284 (16%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484 R+ ++R++ EE R ++ K + +E LK E++++ W K+ + + R Sbjct: 421 REQQLRREQEEERHEQ----KHEQERREQRLK----REQEERRDWLKREEETERHEQERR 472 Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELRE----KEEEEE--- 537 + + + Q +E E + L + ++R+++ EQ+E RE ++EEEE Sbjct: 473 KQQLKRD---QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529 Query: 538 ---------PEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEK---------VKRQER 579 + E ++EK +E R+QR +QEE+ +RQ+R Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589 Query: 580 LKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVG 639 LK +Q+ L+ + +K E R ++ +Q+L + E+ E + L + Sbjct: 590 LKREQEERLEQR---LKREEVERLEQEERREQRLKREEPEE----ERRQQLLKSEEQEER 642 Query: 640 SKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683 +Q L+R +Q++++Q ++ +ER R H + R ++ Sbjct: 643 RQQ---QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683 Score = 50.4 bits (119), Expect = 5e-06 Identities = 57/282 (20%), Positives = 123/282 (43%), Gaps = 32/282 (11%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 E +RK + +++ + R ++ QL + +E K +EEE++ ++ +K + Sbjct: 1458 ERHRKFREEEQLLQEREEQ-QLHR-----QERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541 + K + E + +F L + +R+++ + Q R+ EEE+ + Sbjct: 1512 EPERKFLEEEQQLHRQQRQRKF-----LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566 Query: 542 PSDAESSESSDDEKAWVEE--VRKQ---RRLLQQEEKVKRQE-----------RLKEDQQ 585 + + S D K +EE VR+Q R+ ++ E++++RQE + +ED+Q Sbjct: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQ 1626 Query: 586 TVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLE-----DRLKIEAKNGTLSVSDTTVGS 640 + + + ++ E R F + + + + + DR E + + + Sbjct: 1627 LLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRR 1686 Query: 641 KQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHK 682 ++ + EQQ ++QE E+ QE ++LRR K R + Sbjct: 1687 QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728 Score = 50.1 bits (118), Expect = 7e-06 Identities = 61/280 (21%), Positives = 129/280 (46%), Gaps = 28/280 (10%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484 R+++ R+ +EE Q+++ ++ K +E +L++E EE+Q ++ K L + + Sbjct: 1441 RQERERKFLEEE--QQLRQERHRKFREEE--QLLQEREEQQLHRQERDRKFLEE---EQQ 1493 Query: 485 FKVMFENPDFQVDE---ESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKE---EEEEP 538 + + F+ E + E + L ++R++K L E+Q+LR +E + + Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF-LQEEQQLRRQERGQQRRQD 1552 Query: 539 EGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQE---RLKEDQQTVLKPQFYEI 595 + E + E+ + + R+ +E+KV+RQE + ED+Q + + + + Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612 Query: 596 KAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLK------- 648 E R F++ ++L+ + E +L + ++ + + ++ L+ Sbjct: 1613 LRQERDRKFRED---EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669 Query: 649 RSEQQKKQQ-EAEKLHRQERKRLRRSAGHLKSRHKRGRSF 687 R E+Q Q+ E ++L RQER R R R +R R F Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709 Score = 50.1 bits (118), Expect = 7e-06 Identities = 59/276 (21%), Positives = 134/276 (48%), Gaps = 21/276 (7%) Query: 424 YRKDKIRQKIEETRAQRVQLKKLPKVNKELAL-----KLIEEEEEKQKSTWKKK-VKSLP 477 +R+++ R+ +EE + R Q + +EL K +EEE++ + ++K ++ Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQ 1538 Query: 478 NILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE- 536 + +R + ++ D + EE E+ R ++R +K RL EQ+ R+++E + Sbjct: 1539 QLRRQERGQQRRQDRDRKFREE-EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKF 1597 Query: 537 -EPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQ--EEKVKRQER----LKEDQQTVLK 589 E E + E + E+ + R+ +LLQ+ E+++ RQER L+E+ Q + Sbjct: 1598 MEDEQQLRRQEGQQQLRQERD--RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655 Query: 590 PQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKR 649 + +++ + R F++ +++L+ + E +L+ + ++ + + ++ + Sbjct: 1656 EREQQLRHDRD-RKFRE---EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711 Query: 650 SEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 EQQ ++QE E+ R+E + + + R +R R Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR 1747 Score = 47.0 bits (110), Expect = 6e-05 Identities = 62/268 (23%), Positives = 123/268 (45%), Gaps = 34/268 (12%) Query: 423 EYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTD 482 +YRK++ Q+ EE + R + +K + +E + EEEE +Q+ +L + Sbjct: 1079 QYRKEEELQQ-EEEQLLREEPEKRRRQERERQCR--EEEELQQEEE---------QLLRE 1126 Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542 +R K + + Q EE E + L+ + EKR+++ + +E E ++EEE + Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186 Query: 543 SDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLK-----EDQQTVLKPQFY-EIK 596 + + + + EE+++Q+R + ++ +R + LK E + V + Y + + Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD-LKWQWEPEKENAVRDNKVYCKGR 1245 Query: 597 AGEEFRSFKDSATKQKLMNKTLEDRL------KIEAKNGTLSVSDTTVGSKQLTFTLKRS 650 E+FR +DS + + + L+ L E + D ++ L+R Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE---QLERE 1302 Query: 651 EQQ------KKQQEAEKLHRQERKRLRR 672 EQ+ +K QE ++L R+ER+ RR Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRR 1330 Score = 45.8 bits (107), Expect = 1e-04 Identities = 40/191 (20%), Positives = 89/191 (46%), Gaps = 8/191 (4%) Query: 499 ESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSD-DEKAW 557 + E+ R P ++ E+ ++ R Q++ RE E EE K E + DE+ W Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELW 174 Query: 558 VEEVRKQRRLLQQEEKVKRQERLK--EDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMN 615 R+++ ++EE+ +E+L+ + +T P +++ E + +++ Sbjct: 175 ----RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230 Query: 616 KTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK-QQEAEKLHRQERKRLRRSA 674 + +DR+ E + +T + ++ + ++Q++ Q+E E+L + ER+ LRR Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290 Query: 675 GHLKSRHKRGR 685 + + +R R Sbjct: 291 QEEEQQQQRLR 301 Score = 45.1 bits (105), Expect = 2e-04 Identities = 43/216 (19%), Positives = 104/216 (48%), Gaps = 13/216 (6%) Query: 459 EEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRK 518 +EE++++ ++++ P R + + + ++ E E+ L + ++R Sbjct: 115 QEEDQRRFEPRDRQLEEEPG----QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD 170 Query: 519 KKL--RLLEQQELREKEEEEEPEGKPSDAESSESSDDE---KAWVEEVRKQRRLLQQEEK 573 ++L + E QE E+ EEE E+ E D+E + + E+R++ R +Q+++ Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230 Query: 574 VKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSV 633 +RQ+R+ ++++ + + EE + ++ +Q+ + + E K+E + + Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ----EL 286 Query: 634 SDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKR 669 +Q L+R +Q +++QE E+ +QE +R Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 65.5 bits (158), Expect = 2e-10 Identities = 66/275 (24%), Positives = 128/275 (46%), Gaps = 52/275 (18%) Query: 425 RKDKIRQKIEETRAQ-----------RVQLKKLPKVNKEL---ALKLIEEEEEKQKSTWK 470 +++KIR++ E+ R Q R Q +K+ + +E+ K+ E+EE++Q+ W+ Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410 Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEK---RKKKLRLLEQQ 527 ++ K D ++ E+ EE + ++ E +++KLR +E++ Sbjct: 411 QEKK--------------MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456 Query: 528 ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV-------KRQERL 580 E+E+ +E E K E +EK W +Q +LL+QEEK+ RQE Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTW-----RQEKLLKQEEKIWEQEEKMWRQEEK 511 Query: 581 KEDQQTVLKPQFYEIKAGEE--------FRSFKDSATKQKLMNKTLEDRL-KIEAKNGTL 631 +Q+ ++ Q +++ EE ++ +Q++ + LE+RL K+ K L Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL 571 Query: 632 SVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQE 666 + GS++L + + K QEA+ L +Q+ Sbjct: 572 GGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606 Score = 55.5 bits (132), Expect = 2e-07 Identities = 46/242 (19%), Positives = 114/242 (47%), Gaps = 13/242 (5%) Query: 439 QRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDF---- 494 Q V K +V + L+ +++E++ ++K++ + + K+ + Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331 Query: 495 -QVDEESEEFRLLNPLVSKISEK---RKKKLRLLEQQELREKEEEEEPEGKPSDAESSES 550 ++ E+ E+ R + + EK +++K+R E++ R++E+ E + K + E Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMW 391 Query: 551 SDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATK 610 +EK +E ++Q ++ +QE+K++ Q+ +Q+ + Q +I+ EE ++ + Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451 Query: 611 QKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRL 670 + + K E+ K++ + + + + ++ K Q+K ++ EK+ QE K Sbjct: 452 E-VEEKMQEEEEKMQEQEEKIQRQEEKIQEQE----EKTWRQEKLLKQEEKIWEQEEKMW 506 Query: 671 RR 672 R+ Sbjct: 507 RQ 508 Score = 52.8 bits (125), Expect = 1e-06 Identities = 48/251 (19%), Positives = 115/251 (45%), Gaps = 27/251 (10%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE---EKQKSTWKKKVKSLPNILT 481 +++KI+++ E+ Q +++++ + K+ E+EE E++ W+++ K Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK------- 354 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541 + ++ E+ E+ + + EK +++ + +QE + +E+EE+ + K Sbjct: 355 -------IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601 E DEK +E + +QEEK++ E + +DQ+ L+ E K EE Sbjct: 408 MWRQEKKMREQDEKIREQE----EEMWRQEEKIRELEEMMQDQEEKLRE--VEEKMQEEE 461 Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRS----EQQKKQQ 657 ++ K + + ++++ + + L + + ++ + +++K Q+ Sbjct: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521 Query: 658 EAEKLHRQERK 668 + EK+ RQE K Sbjct: 522 QEEKMQRQEEK 532 Score = 45.1 bits (105), Expect = 2e-04 Identities = 55/253 (21%), Positives = 112/253 (44%), Gaps = 21/253 (8%) Query: 429 IRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKSLPNILTDD 483 I + +E A ++L + ++EL K E +E E +KS + VK L L Sbjct: 192 IEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251 Query: 484 RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE---LREKEEEEEPEG 540 + + + + D +E + ++ + E+ + L +QQE R++E+ +E E Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311 Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600 K + E +EK W R++ ++ +QEEK+ +E + + + + + E+ Sbjct: 312 KMCEQELKIREQEEKMW----RQEEKMHEQEEKI------REQEDKMWRQEEKIREQEEK 361 Query: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA- 659 R ++ +Q+ K E KI+ + + + + ++ K Q+KK +E Sbjct: 362 IREQEEKMWRQE--EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD 419 Query: 660 EKLHRQERKRLRR 672 EK+ QE + R+ Sbjct: 420 EKIREQEEEMWRQ 432 Score = 40.4 bits (93), Expect = 0.006 Identities = 52/283 (18%), Positives = 126/283 (44%), Gaps = 39/283 (13%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLP------KVNKELALKLIEEEEEKQKSTWKKKVKS 475 + + +D ++ E+++ + LK++ + ++ + +++ ++ KS++KK+ + Sbjct: 82 KRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEK 141 Query: 476 LPNILTDDRFKVMFENPDFQVDEESEEFRLLNPL----------------VSKISEKRKK 519 + R +V+ + P ++ E + + R N L + K++++R Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDA 201 Query: 520 -KLRL----LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV 574 L L + +EL+EK E + + + ++E SE + K ++ + + LL Q++ Sbjct: 202 PSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQ 261 Query: 575 KRQERLKEDQQTV---LKPQFYE------IKAGEEFRSFKDSATKQKLMNKTLEDRLKIE 625 +RL ++ Q+V L+ Q E + +E + ++ Q+ K E LKI Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR 321 Query: 626 AKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERK 668 + + + + ++ R ++ K ++ EK+ QE K Sbjct: 322 EQEEKMWRQEEKMHEQEEKI---REQEDKMWRQEEKIREQEEK 361 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 65.5 bits (158), Expect = 2e-10 Identities = 66/275 (24%), Positives = 128/275 (46%), Gaps = 52/275 (18%) Query: 425 RKDKIRQKIEETRAQ-----------RVQLKKLPKVNKEL---ALKLIEEEEEKQKSTWK 470 +++KIR++ E+ R Q R Q +K+ + +E+ K+ E+EE++Q+ W+ Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410 Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEK---RKKKLRLLEQQ 527 ++ K D ++ E+ EE + ++ E +++KLR +E++ Sbjct: 411 QEKK--------------MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456 Query: 528 ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV-------KRQERL 580 E+E+ +E E K E +EK W +Q +LL+QEEK+ RQE Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTW-----RQEKLLKQEEKIWEQEEKMWRQEEK 511 Query: 581 KEDQQTVLKPQFYEIKAGEE--------FRSFKDSATKQKLMNKTLEDRL-KIEAKNGTL 631 +Q+ ++ Q +++ EE ++ +Q++ + LE+RL K+ K L Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELL 571 Query: 632 SVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQE 666 + GS++L + + K QEA+ L +Q+ Sbjct: 572 GGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606 Score = 55.5 bits (132), Expect = 2e-07 Identities = 46/242 (19%), Positives = 114/242 (47%), Gaps = 13/242 (5%) Query: 439 QRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDF---- 494 Q V K +V + L+ +++E++ ++K++ + + K+ + Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331 Query: 495 -QVDEESEEFRLLNPLVSKISEK---RKKKLRLLEQQELREKEEEEEPEGKPSDAESSES 550 ++ E+ E+ R + + EK +++K+R E++ R++E+ E + K + E Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMW 391 Query: 551 SDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATK 610 +EK +E ++Q ++ +QE+K++ Q+ +Q+ + Q +I+ EE ++ + Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451 Query: 611 QKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRL 670 + + K E+ K++ + + + + ++ K Q+K ++ EK+ QE K Sbjct: 452 E-VEEKMQEEEEKMQEQEEKIQRQEEKIQEQE----EKTWRQEKLLKQEEKIWEQEEKMW 506 Query: 671 RR 672 R+ Sbjct: 507 RQ 508 Score = 52.8 bits (125), Expect = 1e-06 Identities = 48/251 (19%), Positives = 115/251 (45%), Gaps = 27/251 (10%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE---EKQKSTWKKKVKSLPNILT 481 +++KI+++ E+ Q +++++ + K+ E+EE E++ W+++ K Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEK------- 354 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541 + ++ E+ E+ + + EK +++ + +QE + +E+EE+ + K Sbjct: 355 -------IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601 E DEK +E + +QEEK++ E + +DQ+ L+ E K EE Sbjct: 408 MWRQEKKMREQDEKIREQE----EEMWRQEEKIRELEEMMQDQEEKLRE--VEEKMQEEE 461 Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRS----EQQKKQQ 657 ++ K + + ++++ + + L + + ++ + +++K Q+ Sbjct: 462 EKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQE 521 Query: 658 EAEKLHRQERK 668 + EK+ RQE K Sbjct: 522 QEEKMQRQEEK 532 Score = 44.7 bits (104), Expect = 3e-04 Identities = 55/253 (21%), Positives = 112/253 (44%), Gaps = 21/253 (8%) Query: 429 IRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKSLPNILTDD 483 I + +E A ++L + ++EL K E +E E +KS + VK L L Sbjct: 192 IEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251 Query: 484 RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE---LREKEEEEEPEG 540 + + + + D +E + ++ + E+ + L +QQE R++E+ +E E Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311 Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600 K + E +EK W R++ ++ +QEEK+ +E + + + + + E+ Sbjct: 312 KMCEQELKIREQEEKMW----RQEEKMHEQEEKI------REQEDKMWRQEEKIREQEEK 361 Query: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA- 659 R ++ +Q+ K E KI+ + + + + ++ K Q+KK +E Sbjct: 362 IREQEEKMWRQE--EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD 419 Query: 660 EKLHRQERKRLRR 672 EK+ QE + R+ Sbjct: 420 EKIREQEEEMWRQ 432 Score = 40.4 bits (93), Expect = 0.006 Identities = 52/283 (18%), Positives = 126/283 (44%), Gaps = 39/283 (13%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLP------KVNKELALKLIEEEEEKQKSTWKKKVKS 475 + + +D ++ E+++ + LK++ + ++ + +++ ++ KS++KK+ + Sbjct: 82 KRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEK 141 Query: 476 LPNILTDDRFKVMFENPDFQVDEESEEFRLLNPL----------------VSKISEKRKK 519 + R +V+ + P ++ E + + R N L + K++++R Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDA 201 Query: 520 -KLRL----LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV 574 L L + +EL+EK E + + + ++E SE + K ++ + + LL Q++ Sbjct: 202 LSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQ 261 Query: 575 KRQERLKEDQQTV---LKPQFYE------IKAGEEFRSFKDSATKQKLMNKTLEDRLKIE 625 +RL ++ Q+V L+ Q E + +E + ++ Q+ K E LKI Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR 321 Query: 626 AKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERK 668 + + + + ++ R ++ K ++ EK+ QE K Sbjct: 322 EQEEKMWRQEEKMHEQEEKI---REQEDKMWRQEEKIREQEEK 361 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 62.4 bits (150), Expect = 1e-09 Identities = 44/247 (17%), Positives = 121/247 (48%), Gaps = 33/247 (13%) Query: 424 YRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDD 483 +R++K+R++ ++ Q +++ + + ++ ++ +E++K TW ++ K + Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRE 593 Query: 484 RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPS 543 R K M E + ++E + +++++K++ E++ ++E+ +E E K Sbjct: 594 REKKMREEEEMMREQEEK------------MQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641 Query: 544 DAESSESSDDEKAWVEE-VRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGE-EF 601 + E +EK W ++ + +Q+ L + EK++ QE+++E ++ + + + E K E E Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701 Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661 +++ +++ + E +++ E + + R +++K Q++ EK Sbjct: 702 KTWDQEKMREEESMREREKKMREEEE-------------------MMREQEEKMQEQEEK 742 Query: 662 LHRQERK 668 + QE + Sbjct: 743 MQEQEEE 749 Score = 60.1 bits (144), Expect = 7e-09 Identities = 68/272 (25%), Positives = 125/272 (45%), Gaps = 38/272 (13%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQK-----STWKKKVKS- 475 EE K++ +E R + ++L K N EL KL E EK + K+K++ Sbjct: 200 EELTKERDALSLELYR-NTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERA 258 Query: 476 ---LPNILTDDRFKVMFENPDFQVDEESEEFRL-----------LNPLVSKISEKRKK-- 519 LP + T+ + M+ + ++ E+ ++ R L K+ E+ +K Sbjct: 259 KFLLPQVQTNTLQEEMWRQEE-ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMW 317 Query: 520 --KLRLLEQQ-ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKR 576 + RL EQ+ ELRE+E+E + + + E +EK W +E ++ +QEEK+ R Sbjct: 318 RQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE----EKMREQEEKMWR 373 Query: 577 QERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDT 636 QE +Q+ ++ Q +++ EE +D ++K E+R++ + K V Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK------EERMREQEKMWE-QVEKM 426 Query: 637 TVGSKQLTFTLKRSEQQKKQQEAEKLHRQERK 668 K K +Q++K QE E++ +E+K Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKK 458 Score = 56.6 bits (135), Expect = 7e-08 Identities = 59/265 (22%), Positives = 121/265 (45%), Gaps = 37/265 (13%) Query: 423 EYRKDKIRQKIEETRAQRVQLK-KLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 E K +I+ ++E + + + K LP+V + + +EE+ + KK K + Sbjct: 238 ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 297 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE-EEPEG 540 + + + E ++E + +R L + E R+++ L EQ+ELRE+EE+ +E E Sbjct: 298 QE--ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEE 355 Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600 K + E +EK W R++ RL +QE++++ QE+ DQ+ + Q E Sbjct: 356 KMWEQEEKMREQEEKMW----RQEERLWEQEKQMREQEQKMRDQEERMWEQ------DER 405 Query: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAE 660 R ++ +Q+ M + +E +++ E K+ ++Q+K+ + Sbjct: 406 LREKEERMREQEKMWEQVE-KMREE----------------------KKMQEQEKKTRDQ 442 Query: 661 KLHRQERKRLRRSAGHLKSRHKRGR 685 + QE +R+R ++ + R Sbjct: 443 EEKMQEEERIREREKKMREEEETMR 467 Score = 55.1 bits (131), Expect = 2e-07 Identities = 60/265 (22%), Positives = 122/265 (46%), Gaps = 30/265 (11%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKEL-ALKLIEEEEEK----------QKSTWK 470 +E + K + + E + Q ++LP+ ++L + ++E+EEK Q+ W Sbjct: 469 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG 528 Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELR 530 ++ K ++ M+E + D+E + + + K E+ KK +++++R Sbjct: 529 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD--QEEKMR 586 Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQR---RLLQQEEKVKRQERLKEDQQTV 587 E+E E E K + E +EK +E + Q ++ +QEEK++ QE +Q+ Sbjct: 587 EEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEK 646 Query: 588 LKPQFYEIKAGEEFRSFKDSATKQKLM-NKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFT 646 + Q E K E+ R + K+KL ++ ++++ K++ + + +Q Sbjct: 647 MWEQ--EEKMWEQQRLPEQ---KEKLWEHEKMQEQEKMQEQEEKIW--------EQEKME 693 Query: 647 LKRSEQQKKQQEAEKLHRQERKRLR 671 K EQ+KK + EK+ +E R R Sbjct: 694 KKTQEQEKKTWDQEKMREEESMRER 718 Score = 54.3 bits (129), Expect = 4e-07 Identities = 51/250 (20%), Positives = 125/250 (50%), Gaps = 15/250 (6%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484 ++ ++R++ +E R Q +L++ ++ ++ E+ +E+++ W+++ K R Sbjct: 319 QEKRLREQEKELREQEKELREQKELREQE-----EQMQEQEEKMWEQEEKMREQEEKMWR 373 Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEK-RKKKLRLLEQQELREKEEEEEPEGKPS 543 + + Q+ E+ ++ R + + E+ R+K+ R+ EQ+++ E+ E+ E K Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQ 433 Query: 544 DAESSESSDDEKAWVEE-VRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFR 602 + E +EK EE +R++ + +++EE+ R++ K +Q + +E + +E++ Sbjct: 434 EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ---EENMWE-QEEKEWQ 489 Query: 603 SFKDSATKQKL--MNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQ--QE 658 + K+KL K E KI + + + G ++ + ++ +Q+ Q ++ Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549 Query: 659 AEKLHRQERK 668 EK+ QE+K Sbjct: 550 EEKMRDQEQK 559 Score = 54.3 bits (129), Expect = 4e-07 Identities = 59/291 (20%), Positives = 138/291 (47%), Gaps = 32/291 (10%) Query: 422 EEYRKDKIRQKIEE-TRAQRVQLKKLPKVNKELALKLIEEEE----------EKQKSTWK 470 E+ R++K Q+ E+ TR Q ++++ ++ +E K+ EEEE +++++ W+ Sbjct: 424 EKMREEKKMQEQEKKTRDQEEKMQEEERI-REREKKMREEEETMREQEEKMQKQEENMWE 482 Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEES---EEFRLLNPLVSKISEK---RKKKLRLL 524 ++ K ++ + ++E Q EE +E ++ + EK R++K+R Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542 Query: 525 EQQELREKEEEEEPEGKPSDAES----SESSDDEKAWVEE--VRKQRRLLQQEEKVKRQE 578 E Q ++E+ + E K D E ++K W +E +R++ R+ ++E+K++ +E Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 602 Query: 579 RLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTV 638 + +Q+ ++ Q +++ EE + ++ Q+ K E K+ + + Sbjct: 603 EMMREQEEKMQEQEEKMQEQEE-KMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661 Query: 639 GSKQLTFTL-------KRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHK 682 K+ + K EQ++K E EK+ ++ +++ +++ K R + Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE 712 Score = 52.4 bits (124), Expect = 1e-06 Identities = 61/263 (23%), Positives = 118/263 (44%), Gaps = 52/263 (19%) Query: 429 IRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKSLPNILTDD 483 I + +E A ++L + N+EL K E +E E +KS + VK L L Sbjct: 199 IEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERA 258 Query: 484 RFKVMFENPDFQVDEESEE-FRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542 +F + P Q + EE +R L +++KK+R E++ R++E E EGK Sbjct: 259 KFLL----PQVQTNTLQEEMWRQEEEL-----REQEKKIRKQEEKMWRQEERLREQEGKM 309 Query: 543 SDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGE 599 + E EK W +E R +++ L +QE++++ Q+ L+E ++ + + + + E Sbjct: 310 REQE-------EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE 362 Query: 600 EFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA 659 + R ++ +Q E+RL + K + EQ++K ++ Sbjct: 363 KMREQEEKMWRQ-------EERLWEQEK--------------------QMREQEQKMRDQ 395 Query: 660 EKLHRQERKRLRRSAGHLKSRHK 682 E+ ++ +RLR ++ + K Sbjct: 396 EERMWEQDERLREKEERMREQEK 418 Score = 49.7 bits (117), Expect = 9e-06 Identities = 42/186 (22%), Positives = 89/186 (47%), Gaps = 15/186 (8%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEE---KQKSTWKKKVKSLPN 478 EE +++ ++ EE R Q +K+ +E K+ E+EEE +++ W+++ K Sbjct: 712 EESMREREKKMREEEEMMREQEEKM----QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ 767 Query: 479 ILTDDRFKVMFENPDFQ----VDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEE 534 ++ + ++E+ Q + E+ E+ R + EK + + + QE + + Sbjct: 768 QRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQ 827 Query: 535 EEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYE 594 EE+ G+ E +EK W +E + + ++ QEEK++ QE Q+ ++ Q + Sbjct: 828 EEKMWGQ----EEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883 Query: 595 IKAGEE 600 ++ EE Sbjct: 884 MRGQEE 889 Score = 48.9 bits (115), Expect = 2e-05 Identities = 50/252 (19%), Positives = 113/252 (44%), Gaps = 36/252 (14%) Query: 423 EYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEE---EEKQKSTWKKKVKSLPNI 479 E+ K + ++K++E + + +K+ K +E K ++E EE+ +KK++ + Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728 Query: 480 LTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPE 539 + + K+ + Q EE E +++ ++ EQ+E + E++ PE Sbjct: 729 MREQEEKMQEQEEKMQEQEE---------------EMWEQEEKMWEQEE-KMWEQQRLPE 772 Query: 540 GKPSDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIK 596 K E + + EK W +E + ++ ++ QEEK++ QE Q+ + Q ++ Sbjct: 773 QKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMW 832 Query: 597 AGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQ 656 EE K ++K+ + + K++ + + + + R +++K + Sbjct: 833 GQEE----KMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKM----------RGQEEKMR 878 Query: 657 QEAEKLHRQERK 668 ++ EK+ QE K Sbjct: 879 EQEEKMRGQEEK 890 Score = 48.5 bits (114), Expect = 2e-05 Identities = 54/261 (20%), Positives = 130/261 (49%), Gaps = 28/261 (10%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE---EKQKSTWKKKVKSLPNILT 481 +++K+R++ E R + ++++ ++ +E K+ E+EE E+++ W+++ K Sbjct: 581 QEEKMREE-ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM------ 633 Query: 482 DDRFKVMFENPD--FQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPE 539 ++ + M+E + ++ +E+ E + L K+ E K + + + QE EK E+E Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE-KMQEQEEKIWEQEKM 692 Query: 540 GKPSDAESSESSDDEKAWVEEVRKQR--RLLQQEEKVKRQERLKEDQQTVLKPQFYEIKA 597 K + + ++ D EK EE ++R ++ ++EE ++ QE ++Q+ ++ Q E+ Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE 752 Query: 598 GEE---------FRSFKDSATKQKLM-NKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTL 647 EE + + K+KL ++ ++++ KI + + + + ++ Sbjct: 753 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE---EK 809 Query: 648 KRSEQQKKQQEAEKLHRQERK 668 R +++K + + EK+ QE K Sbjct: 810 MRGQEEKMRGQEEKMWGQEEK 830 Score = 36.2 bits (82), Expect = 0.10 Identities = 33/167 (19%), Positives = 76/167 (45%), Gaps = 14/167 (8%) Query: 524 LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQ-------EEKVKR 576 + +EL++K E + + +++E SE + K ++ + + LL Q EE ++ Sbjct: 218 ITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 277 Query: 577 QERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDT 636 +E L+E ++ + K + + E R + +Q+ E RL+ + K + Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEK-------EL 330 Query: 637 TVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683 K+L + EQ+++ QE E+ ++ +++R + + +R Sbjct: 331 REQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 377 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 62.0 bits (149), Expect = 2e-09 Identities = 61/273 (22%), Positives = 137/273 (50%), Gaps = 23/273 (8%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKK--KVKSLPNILTD 482 R++KI+++ E+ R Q ++++ ++ E K+ +EE W+K K++ L + + Sbjct: 300 REEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE----MMWEKEEKIRELEEKMHE 355 Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKI---SEK-RKKKLRLLEQQELREKEEEE-- 536 K+ + Q +E+ E +K+ EK R+++ ++ EQ+E+ +++EE+ Sbjct: 356 QE-KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414 Query: 537 EPEGKPSDAESSESSDDEKA--WVEEVRKQ-RRLLQQEEKVKRQERLKEDQQTVLKPQFY 593 E E K + E +EK E++R+Q +++ +QEEK++ QE + ++Q+ + Q Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ-- 472 Query: 594 EIKAGEEFRSFKDSATKQKLMNKTL-EDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQ 652 E K E+ ++ K + + + E KI + + + + ++ K EQ Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE----KMWEQ 528 Query: 653 QKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 ++K E E+ +++ +++RR ++ + R R Sbjct: 529 EEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLR 561 Score = 55.1 bits (131), Expect = 2e-07 Identities = 59/304 (19%), Positives = 141/304 (46%), Gaps = 36/304 (11%) Query: 407 RLYHKVKLMVNPFAYEEYRKDKIRQKIEETRA----QRVQL------KKLPKVNKELALK 456 +L K++L+ + + + ++++K+E + Q++Q K+L V+ +L + Sbjct: 213 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 272 Query: 457 LIEEE------EEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLV 510 + E E +++++ W+++ K +R + + E + ++ E+ E+ R ++ Sbjct: 273 VEENELWNRLNQQQEEKMWRQEEK------IQEREEKIQEQEE-KIREQEEKMRRQEEMM 325 Query: 511 SKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQ 570 + EK +++ ++ ++E + +E EE+ + E E +E E++R+Q + +Q Sbjct: 326 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE----EKIREQEKRQEQ 381 Query: 571 EEKVKRQERLKEDQQTVLKP-----QFYEIKAGE-EFRSFKDSATKQKLMNKTLEDRLKI 624 E K+ RQE +Q+ ++ Q E K GE E + ++ Q+ K KI Sbjct: 382 EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI 441 Query: 625 EAKNGTLSVSDTTVGSKQLTF---TLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRH 681 + + + + ++ K EQ+ K E E +++ +++RR ++ + Sbjct: 442 REQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501 Query: 682 KRGR 685 K+ R Sbjct: 502 KKIR 505 Score = 54.3 bits (129), Expect = 4e-07 Identities = 44/211 (20%), Positives = 110/211 (52%), Gaps = 21/211 (9%) Query: 424 YRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDD 483 + ++KIR++ EE R + ++++ K ++ A +EE+ +++ ++K++ ++ + Sbjct: 354 HEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ---EEKIREQEEMMQEQ 409 Query: 484 RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE------- 536 K+ + ++ E+ EE + + + EK +++ + + +QE + +E+EE Sbjct: 410 EEKM--GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 467 Query: 537 ---EPEGKPSDAESSESSDDEK--AWVEEVRKQ-RRLLQQEEKVKRQERLKEDQQTVLKP 590 E EGK + E+ +EK E++R+Q +++ +QEEK++ QE + ++Q+ + Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527 Query: 591 QFYEIKAGEEFRSFKDSATKQKLMNKTLEDR 621 Q E K E+ ++ K + + + ++ Sbjct: 528 Q--EEKMCEQEEKMQEQEEKMRRQEEKMREQ 556 Score = 53.9 bits (128), Expect = 5e-07 Identities = 51/264 (19%), Positives = 122/264 (46%), Gaps = 23/264 (8%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484 +++ + +K E+ R Q + + + +EL K+ E+E+ +++ +++ + + Sbjct: 321 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 380 Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSD 544 + + ++ E+ E+ R ++ + EK + +QE + E+EEE + Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEEK-------MGEQEEKMWEQEEEMQ----- 428 Query: 545 AESSESSDDEKAWVEEVRKQ-RRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRS 603 E + + E++R+Q +++ +QEEK++ QE + ++Q+ + Q E K E+ Sbjct: 429 ----EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ--EGKMCEQEAK 482 Query: 604 FKDSATKQKLM-NKTLEDRLKIEAKNGTLSVSDTTV---GSKQLTFTLKRSEQQKKQQEA 659 ++ K + K E KI + + + + K K EQ++K QE Sbjct: 483 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 542 Query: 660 EKLHRQERKRLRRSAGHLKSRHKR 683 E+ R++ +++R L+ + ++ Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEK 566 Score = 44.7 bits (104), Expect = 3e-04 Identities = 36/154 (23%), Positives = 81/154 (52%), Gaps = 11/154 (7%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484 ++++++++ E+ R Q ++++ K +E K+ E+EE Q+ ++K+ + + Sbjct: 423 QEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ--EEKMGEQEGKMCEQE 480 Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE---EPEGK 541 K+ + + ++ + E+ R + + EK +++ ++++QE + E+EE E E K Sbjct: 481 AKM--QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVK 575 + E +EK +EV RL QQEEK++ Sbjct: 539 MQEQEEKMRRQEEKMREQEV----RLRQQEEKMQ 568 Score = 32.0 bits (71), Expect = 2.0 Identities = 34/165 (20%), Positives = 69/165 (41%), Gaps = 19/165 (11%) Query: 524 LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED 583 + +EL+EK + + + + ++E SE + K ++ + + LL Q++ + L ++ Sbjct: 202 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 261 Query: 584 QQTV---LKPQFYE------IKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVS 634 Q+V L+ Q E + +E + ++ Q+ K E KI + + Sbjct: 262 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321 Query: 635 DTTVGSKQLTFTL----------KRSEQQKKQQEAEKLHRQERKR 669 + + K+ K E ++K E EK+ QE KR Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 366 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 61.6 bits (148), Expect = 2e-09 Identities = 57/273 (20%), Positives = 133/273 (48%), Gaps = 27/273 (9%) Query: 425 RKDKIRQKIEETRAQRVQL-KKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDD 483 +++KIR++ E+ R Q ++ ++ K++++ ++ EE+ ++Q+ W+++ K Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE-EEKRQEQEEMWRQEEKIHEQEEIWR 493 Query: 484 RFKVMFENPDFQVDEESEEFRL---LNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540 + + M E + +E + +R + KI E+ +K R +++++RE+EE E Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR--QEEKIREQEEMWREEE 551 Query: 541 KPSD-----AESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQERLKEDQQTVLKPQF 592 K + E ++K W +E + ++ ++ +QEEK++ QE +++Q+ + Q Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611 Query: 593 YEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQ 652 +I+ EE Q+ K E KI + + +G ++ K EQ Sbjct: 612 EKIREQEE--------KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE----EKMCEQ 659 Query: 653 QKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 ++K QE E+ ++ +++R ++ + ++ R Sbjct: 660 EEKMQEQEETMWRQEEKIREQEKKIREQEEKIR 692 Score = 61.2 bits (147), Expect = 3e-09 Identities = 57/250 (22%), Positives = 123/250 (49%), Gaps = 17/250 (6%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKK--KVKSLPNILTD 482 +++KIR++ E+ R Q ++++ ++ E K+ +EE W+K K++ ++ + Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE----MMWEKEEKMRRQEEMMWE 374 Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542 K+ + + E+ E+ R L + + + R+++ + E++++RE+E+ +E E K Sbjct: 375 KEEKM--RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432 Query: 543 SDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED----QQTVLKPQFYEIKAG 598 E +EK +E +++ +QEEK+ QE+++E+ +Q + Q +I Sbjct: 433 WRQEEKIREQEEKIREQE----KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ 488 Query: 599 EEFRSFKDSATKQKLMNKTLEDRL-KIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQ 657 EE K+ +Q+ + E+++ + E K K K EQ++ + Sbjct: 489 EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWR 548 Query: 658 EAEKLHRQER 667 E EK+H QE+ Sbjct: 549 EEEKMHEQEK 558 Score = 60.8 bits (146), Expect = 4e-09 Identities = 61/272 (22%), Positives = 131/272 (48%), Gaps = 28/272 (10%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEE---KQKSTWKK--KVKSL 476 E+ R+++ RQ+ EE Q ++ + ++ ++ K+ E+EE+ +++ W++ K++ Sbjct: 464 EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE-KMHEQEEKIRKQEEKVWRQEEKIREQ 522 Query: 477 PNILTDDRFKVMFENPDFQVDEES--EEFRLLNPLVSKISEKRKKKLRLLEQQELREKEE 534 + + K+ + + EE EE ++ EKR+++ + +QE + +E+ Sbjct: 523 EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582 Query: 535 EEE---PEGKPSDAESSESSDDEKAWVEE--VRKQRRLLQ-QEEKVKRQERLKEDQQTVL 588 EE+ E K + E +EK W +E +R+Q +Q QEEK++ QE +Q+ + Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT 642 Query: 589 KPQFYEIKAGEEFRSFKDSATKQKLMNKTL--------EDRLKIEAKNGTLSVSDTTVGS 640 + Q E K GE+ + K + +T+ E KI + + + + Sbjct: 643 QEQ--EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQE 700 Query: 641 KQLTFTLKRSEQQKKQQEAEKLHRQERKRLRR 672 ++ K EQ++K E E+ +++ +++RR Sbjct: 701 QEE----KMWEQEEKMCEQEEKMQEQEEKMRR 728 Score = 53.1 bits (126), Expect = 8e-07 Identities = 45/246 (18%), Positives = 123/246 (50%), Gaps = 30/246 (12%) Query: 425 RKDKIRQKIEETRAQRVQL-KKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDD 483 +++KIR++ E+ R Q ++ ++ K+ ++ + EE+ +Q+ W+++ + + Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ-------E 567 Query: 484 RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPS 543 + M+ + ++ E+ E+ + + EKR+++ + +QE + +E+EE+ + + Sbjct: 568 QEDKMWRQEE-KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEE 626 Query: 544 DAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRS 603 E E+ + + ++++ Q+E+ +++E+++E ++T+ + + + ++ R Sbjct: 627 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686 Query: 604 FKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQE-AEKL 662 ++ +Q+ M + E+++ + + K EQ++K QE EK+ Sbjct: 687 QEEKIREQEEMMQEQEEKMWEQEE--------------------KMCEQEEKMQEQEEKM 726 Query: 663 HRQERK 668 RQE K Sbjct: 727 RRQEEK 732 Score = 49.7 bits (117), Expect = 9e-06 Identities = 39/166 (23%), Positives = 85/166 (51%), Gaps = 21/166 (12%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484 +++KIR++ E+ + Q ++ K + +E K+ E+EE+ ++ ++K++ + + Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ--EEKIREQEEMTQEQE 646 Query: 485 FKV------MFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE-- 536 K+ M E + ++E +R + + + R+++ ++ EQ+E+ +++EE+ Sbjct: 647 EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 706 Query: 537 -------EPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVK 575 E E K + E +EK W +EV RL QQEEK++ Sbjct: 707 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV----RLRQQEEKMQ 748 Score = 48.9 bits (115), Expect = 2e-05 Identities = 39/179 (21%), Positives = 90/179 (50%), Gaps = 11/179 (6%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484 +++KIR++ E+ Q ++++ + +E K+ ++EE+ ++ ++K++ + + Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ--EEKIQEQEEKIREQE 632 Query: 485 FKVMFENPDFQVDEES--EEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE-EEPEGK 541 K+ + Q EE E+ + K+ E+ + R +++++RE+E++ E E K Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR--QEEKIREQEKKIREQEEK 690 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600 + E +EK W +E ++ +QEEK++ QE Q+ + Q ++ EE Sbjct: 691 IREQEEMMQEQEEKMWEQE----EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745 Score = 48.5 bits (114), Expect = 2e-05 Identities = 60/275 (21%), Positives = 127/275 (46%), Gaps = 25/275 (9%) Query: 425 RKDKIRQKIEETRAQR----VQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKS 475 +K K + IEE +R ++L + ++EL K + +E E +KS + VK Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246 Query: 476 LPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE 535 L L + + + + D +E + ++ + E+ + RL +QQE + +E Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 306 Query: 536 E---EPEGKPSDAESSESSDDEKAWVEEVRKQRR---LLQQEEKVKRQERLK-EDQQTVL 588 E E E K + E +EK +E + +R+ + ++EEK++RQE + E ++ + Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366 Query: 589 KPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLK 648 + + + E+ R ++ +++ + LE+++ + K ++ K Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK--------IREQEEKRQEEEK 418 Query: 649 RSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683 EQ+K+Q++ K+ RQE K +R ++ + K+ Sbjct: 419 IREQEKRQEQEAKMWRQEEK-IREQEEKIREQEKK 452 Score = 42.0 bits (97), Expect = 0.002 Identities = 38/194 (19%), Positives = 84/194 (43%), Gaps = 45/194 (23%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484 ++DK+ ++ E+ R Q ++ + + +E E+ +E+++ WK++ K Sbjct: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQE----EKRQEQEEKMWKQEEK---------- 613 Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE-------- 536 + ++ E+ E+ R + + E +++ + +QE + E+EE Sbjct: 614 ----IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669 Query: 537 ----------------EPEGKPSDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQ 577 E E K + E +EK W +E + ++ ++ +QEEK++RQ Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729 Query: 578 ERLKEDQQTVLKPQ 591 E +Q+ L+ Q Sbjct: 730 EEKMWEQEVRLRQQ 743 Score = 30.0 bits (66), Expect = 7.5 Identities = 47/225 (20%), Positives = 86/225 (38%), Gaps = 55/225 (24%) Query: 462 EEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKL 521 EE K ++ N +TD+ K +N Q E+ +L+ S+I K+ Sbjct: 196 EELTKERDALSLELYRNTITDEELKE--KNAKLQ-----EKLQLVESEKSEIQLNVKELK 248 Query: 522 RLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRL-LQQEEKVKRQERL 580 R LE+ +L +++ + E E S +A VEE RL QQEEK+ RQE Sbjct: 249 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK 308 Query: 581 KEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGS 640 ++ + ++ Q +I+ EE Sbjct: 309 IQEWEEKIQEQEEKIREQEE---------------------------------------- 328 Query: 641 KQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 K EQ++K + E++ ++ +++RR + + ++ R Sbjct: 329 -------KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 61.6 bits (148), Expect = 2e-09 Identities = 58/266 (21%), Positives = 130/266 (48%), Gaps = 10/266 (3%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 EE ++ +Q E+ + R Q +++ + ++ L K EE +Q+ W+++ K Sbjct: 337 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREK--EERMREQEKMWEQEEKMQEEERI 394 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE-LREKEEEEEPEG 540 +R K M E + + E+ E+ + + + EK ++ RL EQ+E L E+E+ +E E Sbjct: 395 REREKKMREEEE-TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 453 Query: 541 KPSDAESSESSDDEKAWVEEVR--KQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAG 598 K + E + D E+ W +E + +Q ++ +QE+++ QE DQ+ + Q E + Sbjct: 454 KIWEQEE-KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ--EERMW 510 Query: 599 EEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKR-SEQQKKQQ 657 E+ ++ + + K + K+ + T T ++ +R E++KK + Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR 570 Query: 658 EAEKLHRQERKRLRRSAGHLKSRHKR 683 E E++ R++ ++++ ++ + ++ Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEK 596 Score = 61.2 bits (147), Expect = 3e-09 Identities = 52/277 (18%), Positives = 132/277 (47%), Gaps = 23/277 (8%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKEL-ALKLIEEEEEK----------QKSTWK 470 +E + K + + E + Q ++LP+ ++L + ++E+EEK Q+ W Sbjct: 411 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG 470 Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELR 530 ++ K ++ M+E + D+E + + + + R+K+ R+ EQ+++ Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530 Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKP 590 ++EE+ E K + E +EK +R++ R+ ++E+K++ +E + +Q+ ++ Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEK-----MREEERMREREKKMREEEEMMREQEEKMQE 585 Query: 591 QFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKI--EAKNGTLSVSDTTVGSKQLTFTLK 648 Q +++ EE + ++ Q+ K E K+ + + + + + ++ K Sbjct: 586 QEEKMREQEE-KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE----EK 640 Query: 649 RSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 EQ++K E E+ R++ +++R ++ + ++ R Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 677 Score = 58.5 bits (140), Expect = 2e-08 Identities = 66/271 (24%), Positives = 115/271 (42%), Gaps = 62/271 (22%) Query: 429 IRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKSLPNILTDD 483 I + +E A ++L + N+EL K E +E E +KS + VK L L Sbjct: 161 IEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERA 220 Query: 484 RF---KVMFENPDFQVDEESEEFRLLNPLVSKISEK----------------------RK 518 +F +V ++ + EE R + K EK R+ Sbjct: 221 KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR 280 Query: 519 KKLRLLEQQ-ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQ 577 ++ RL EQ+ ELRE+E+E + K + E +EK W +E ++ +QEEK+ RQ Sbjct: 281 QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE----EKMREQEEKMWRQ 336 Query: 578 ERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTT 637 E +Q+ ++ Q +++ EE +D ++K E+R++ + Sbjct: 337 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREK------EERMREQE----------- 379 Query: 638 VGSKQLTFTLKRSEQQKKQQEAEKLHRQERK 668 K EQ++K QE E++ +E+K Sbjct: 380 ----------KMWEQEEKMQEEERIREREKK 400 Score = 55.8 bits (133), Expect = 1e-07 Identities = 42/185 (22%), Positives = 90/185 (48%), Gaps = 21/185 (11%) Query: 427 DKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFK 486 +++R+K E R Q+ ++ K+ +E ++ +E++K TW ++ K +R K Sbjct: 514 ERLREKEERMREQKKMWQQEEKMREE------KKTQEQEKKTWDQEEKMREEERMREREK 567 Query: 487 VMFENPDF------QVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540 M E + ++ E+ E+ R + + EK +++ + +QE + E+EEE + Sbjct: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627 Query: 541 KPS-----DAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEI 595 + + E +EK W +E ++ +QEEK++ QE + Q+ ++ Q ++ Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQE----EKMREQEEKMREQEEKMQGQEEKMREQEEKM 683 Query: 596 KAGEE 600 + EE Sbjct: 684 QGQEE 688 Score = 54.7 bits (130), Expect = 3e-07 Identities = 78/400 (19%), Positives = 176/400 (44%), Gaps = 42/400 (10%) Query: 277 SVHFQDSLDLILSADSRIVKMWNKNSGKIFTSLEPEHDLNDVCLYPNSGMLLTANETPKM 336 S HF L LSA V W+K + + L E D + LY N+ +T E K Sbjct: 136 SWHFAGELQRALSA----VSTWHKKADRYIEELTKERDALSLELYRNT---ITNEELKKK 188 Query: 337 GIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLR 396 L L E+ +S + + K + +K L + + L+ Sbjct: 189 NAELQEKL---------------RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 233 Query: 397 AYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALK 456 M ++R K + + ++++R++ + R Q ++++ K +E + Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQ--EERLREQEGKMREQEEKMRRQEKRLREQEKE 291 Query: 457 LIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEK 516 L E+E+E ++ +KK++ + + K M+E + ++E + +R L + + Sbjct: 292 LREQEKELRE---QKKLREQEEQMQEQEEK-MWEQEEKMREQEEKMWRQEERLWEQEKQM 347 Query: 517 RKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEE--VRKQRRLLQQEEKV 574 R+++ ++ +Q+E +++E E + + EK W +E ++++ R+ ++E+K+ Sbjct: 348 REQEQKMRDQEERMWEQDERLRE------KEERMREQEKMWEQEEKMQEEERIREREKKM 401 Query: 575 KRQERLKEDQQTVLKPQFYEI--KAGEEFRSFKDSATKQKL--MNKTLEDRLKIEAKNGT 630 + +E +Q+ ++ Q + + +E++ + K+KL K E KI + Sbjct: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461 Query: 631 LSVSDTTVGSKQLTFTLKRSEQQKKQ--QEAEKLHRQERK 668 + + G ++ + ++ +Q+ Q ++ EK+ QE+K Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501 Score = 52.0 bits (123), Expect = 2e-06 Identities = 37/175 (21%), Positives = 89/175 (50%), Gaps = 10/175 (5%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484 +++K++++ E+ R Q ++ + + +E K+ E+EE+ + + K++ ++ + Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638 Query: 485 FKV------MFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEP 538 K+ M+E + ++ E+ E+ R + EK +++ ++ QE + +E+EE+ Sbjct: 639 EKMQEQEEKMWEQEE-KMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKM 697 Query: 539 EGKPSDAESSESS---DDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKP 590 G+ E +EK W +E +++ +++K K QERL E ++ +P Sbjct: 698 RGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEP 752 Score = 42.0 bits (97), Expect = 0.002 Identities = 55/258 (21%), Positives = 108/258 (41%), Gaps = 33/258 (12%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE---EKQKSTWKKKVKSLPNILT 481 +++KIR + EE Q ++ + K+ +E ++ E+EE ++++ W ++ + Sbjct: 458 QEEKIRDQ-EEMWGQEKKMWRQEKM-REQEDQMWEQEEKMRDQEQKMWDQEERMWEQ--- 512 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE----- 536 D+R + E Q +E ++ ++ EK+ ++E R +E E+ Sbjct: 513 DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572 Query: 537 -----EPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQ 591 E E K + E +EK W +E + Q +QEEK+ QE +Q+ K Q Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ----EQEEKMWEQEEKMWEQEEEDKMQ 628 Query: 592 FYEIKAGEEFRSFKDSATKQ-KLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRS 650 E E+ ++ K + K E K+ + + + + R Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM----------RE 678 Query: 651 EQQKKQQEAEKLHRQERK 668 +++K Q + EK+ QE K Sbjct: 679 QEEKMQGQEEKMREQEEK 696 Score = 40.8 bits (94), Expect = 0.004 Identities = 34/167 (20%), Positives = 78/167 (46%), Gaps = 14/167 (8%) Query: 524 LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQ-------EEKVKR 576 + +EL++K E + + + +++E SE + K ++ + + LL Q EE ++ Sbjct: 180 ITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 239 Query: 577 QERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDT 636 +E L+E ++ + K + + E R + +Q+ + E RL+ + K + Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEK-------EL 292 Query: 637 TVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683 K+L K EQ+++ QE E+ ++ +++R + + +R Sbjct: 293 REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 61.2 bits (147), Expect = 3e-09 Identities = 60/250 (24%), Positives = 124/250 (49%), Gaps = 36/250 (14%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKK--KVKSLPNILTD 482 +++KIR++ E+ R Q ++++ ++ E K+ +EE W+K K++ L ++ + Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE----MMWEKEEKMRRLEEMMWE 374 Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542 K+ +++E+ E KI E+ +K+ E++++RE+E+ +E E K Sbjct: 375 KEEKIR------ELEEKMHE-------QEKIREQEEKRQ---EEEKIREQEKRQEQEAKM 418 Query: 543 SDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED----QQTVLKPQFYEIKAG 598 E +EK +E +++ +QEEK+ QE+++E+ +Q + Q +I+ Sbjct: 419 WRQEEKIREQEEKIREQE----KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 474 Query: 599 EEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQE 658 EE K+ +Q+ + K E + E K + D ++ + R E++ ++QE Sbjct: 475 EEIWRQKEKMHEQEKIRKQEEKVWRQEEK-----MHDQEEKIREQEEKMWRQEEKIREQE 529 Query: 659 AEKLHRQERK 668 EK+ QE K Sbjct: 530 -EKIREQEEK 538 Score = 60.1 bits (144), Expect = 7e-09 Identities = 59/249 (23%), Positives = 121/249 (48%), Gaps = 32/249 (12%) Query: 425 RKDKIRQKIEETRAQRVQL-KKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDD 483 +++KIR++ E+ R Q ++ ++ K++++ ++ EE+ ++Q+ W+++ K Sbjct: 421 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE-EEKRQEQEEMWRQEEKIREQEEIWR 479 Query: 484 RFKVMFENPDFQVDEES--EEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE-EEPEG 540 + + M E + EE + ++ KI E+ +K R +++++RE+EE+ E E Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR--QEEKIREQEEKIREQEE 537 Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600 K + E +EK + +Q +Q++EK++RQE +Q+ ++ Q +I+ EE Sbjct: 538 KIREQEEMMQEQEEK-----MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592 Query: 601 FRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQE-A 659 K E KI + + + + ++ K EQ++K QE Sbjct: 593 ---------------KIWEQEEKIREQEEMMQEQEEKMWEQE----EKMCEQEEKMQEQE 633 Query: 660 EKLHRQERK 668 EK+ RQE K Sbjct: 634 EKMRRQEEK 642 Score = 55.1 bits (131), Expect = 2e-07 Identities = 43/161 (26%), Positives = 86/161 (53%), Gaps = 20/161 (12%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDR 484 +++KIR++ E+ R Q ++++ ++ +E K+ E+EE+ Q+ ++K++ + + Sbjct: 521 QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE---QEKMRRQEEKIREQE 577 Query: 485 FKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE---EPEGK 541 K+ E+ E+ R + + EK +++ ++++QE + E+EE E E K Sbjct: 578 EKIR---------EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV-KRQERLK 581 + E +EK W +EV RL QQEEK+ + QE L+ Sbjct: 629 MQEQEEKMRRQEEKMWEQEV----RLRQQEEKMQEHQEHLE 665 Score = 54.3 bits (129), Expect = 4e-07 Identities = 52/284 (18%), Positives = 131/284 (46%), Gaps = 26/284 (9%) Query: 407 RLYHKVKLMVNPFAYEEYRKDKIRQKIEETRA----QRVQL------KKLPKVNKELALK 456 +L K++L+ + + + ++++K+E + Q++Q K+L V+ +L + Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284 Query: 457 LIEEE------EEKQKSTWKK--KVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNP 508 + E E +++++ W++ K++ + + K+ + ++ E+ E+ R Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI--REQEEKIREQEEKMRRQEE 342 Query: 509 LVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLL 568 ++ + EK +++ ++ ++E + + EE K E E+ E++R+Q Sbjct: 343 MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ---EKIREQEEKR 399 Query: 569 QQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKN 628 Q+EEK++ QE+ +E + + + E K E+ ++ K + + ++ KI + Sbjct: 400 QEEEKIREQEKRQEQEAKMWRQ---EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 456 Query: 629 GTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRR 672 + +++ + Q++K E EK+ +QE K R+ Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ 500 Score = 54.3 bits (129), Expect = 4e-07 Identities = 45/197 (22%), Positives = 106/197 (53%), Gaps = 22/197 (11%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELAL------KLIEEEE---EKQKSTWKK--KV 473 +++KIR++ EE Q+ ++ + K+ K+ K+ ++EE E+++ W++ K+ Sbjct: 467 QEEKIREQ-EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525 Query: 474 KSLPNILTDDRFKV-----MFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE 528 + + + K+ M + + ++ E+ E+ + + + + R+++ ++ EQ+E Sbjct: 526 REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKE 585 Query: 529 -LREKEEEE-EPEGKPSDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQERLKED 583 +RE+EE+ E E K + E +EK W +E + ++ ++ +QEEK++RQE + Sbjct: 586 KIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 645 Query: 584 QQTVLKPQFYEIKAGEE 600 Q+ L+ Q +++ +E Sbjct: 646 QEVRLRQQEEKMQEHQE 662 Score = 52.4 bits (124), Expect = 1e-06 Identities = 64/277 (23%), Positives = 125/277 (45%), Gaps = 43/277 (15%) Query: 425 RKDKIRQKIEETRAQR----VQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKS 475 +K K + IEE +R ++L + ++EL K + +E E +KS + VK Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246 Query: 476 LPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE 535 L L + + + + D +E + ++ + E+ + RL +QQE + +E Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 306 Query: 536 E---EPEGKPSDAESSESSDDEKAWVEEVRKQRR---LLQQEEKVKRQERL---KEDQQT 586 E E E K + E +EK +E + +R+ + ++EEK++RQE + KE++ Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366 Query: 587 VLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFT 646 L+ +E + E+ R ++ +Q+ + + E R + E Sbjct: 367 RLEEMMWEKE--EKIRELEEKMHEQEKIREQEEKRQEEE--------------------- 403 Query: 647 LKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683 K EQ+K+Q++ K+ RQE K +R ++ + K+ Sbjct: 404 -KIREQEKRQEQEAKMWRQEEK-IREQEEKIREQEKK 438 Score = 50.8 bits (120), Expect = 4e-06 Identities = 43/198 (21%), Positives = 100/198 (50%), Gaps = 25/198 (12%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE--EKQKSTWKKKVKSLPNI 479 E+ R+++ RQ+ EE Q ++++ ++ ++ K+ E+E+ ++++ W+++ K Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE-KMHEQEKIRKQEEKVWRQEEK----- 503 Query: 480 LTDDRFKVM------------FENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQ 527 + D K+ + ++ E+ E+ R ++ + EK ++ +++Q Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563 Query: 528 ELREKEEEE--EPEGKPSDAESSESSDDEKAWVEE--VRKQRRLLQ-QEEKVKRQERLKE 582 E ++EE+ E E K + + +EK W +E +R+Q ++Q QEEK+ QE Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMC 623 Query: 583 DQQTVLKPQFYEIKAGEE 600 +Q+ ++ Q +++ EE Sbjct: 624 EQEEKMQEQEEKMRRQEE 641 Score = 30.0 bits (66), Expect = 7.5 Identities = 47/225 (20%), Positives = 86/225 (38%), Gaps = 55/225 (24%) Query: 462 EEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKL 521 EE K ++ N +TD+ K +N Q E+ +L+ S+I K+ Sbjct: 196 EELTKERDALSLELYRNTITDEELKE--KNAKLQ-----EKLQLVESEKSEIQLNVKELK 248 Query: 522 RLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRL-LQQEEKVKRQERL 580 R LE+ +L +++ + E E S +A VEE RL QQEEK+ RQE Sbjct: 249 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK 308 Query: 581 KEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGS 640 ++ + ++ Q +I+ EE Sbjct: 309 IQEWEEKIQEQEEKIREQEE---------------------------------------- 328 Query: 641 KQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 K EQ++K + E++ ++ +++RR + + ++ R Sbjct: 329 -------KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366 >gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens] Length = 1293 Score = 61.2 bits (147), Expect = 3e-09 Identities = 59/251 (23%), Positives = 125/251 (49%), Gaps = 20/251 (7%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 +E R+ ++R K EE +R + +L + +E+ L+ +EEE K++ + + L Sbjct: 733 QERREAEMRAKREEEERKRQE--ELRRQQEEI-LRRQQEEERKRREEEELARRKQEEALR 789 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541 R + + + E EE + + ++ E+R+++ +Q+EL K+EEE + Sbjct: 790 RQREQEIA----LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 845 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601 + E+ ++ + +EE + RL +EE+ KR+E + Q+ +++ + + E Sbjct: 846 REEEEAQRRLEENRLRMEE--EAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEAL 900 Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661 R + +Q+L ++K+ + + S+TT Q T +L +E QK ++E E+ Sbjct: 901 RRLQQQQQQQQLA------QMKLPSSSTWGQQSNTTACQSQATLSL--AEIQKLEEERER 952 Query: 662 LHRQERKRLRR 672 R+E++R +R Sbjct: 953 QLREEQRRQQR 963 Score = 52.8 bits (125), Expect = 1e-06 Identities = 37/169 (21%), Positives = 82/169 (48%), Gaps = 8/169 (4%) Query: 516 KRKKKLR------LLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQ 569 KR+++LR L QQE K EEE + E+ +++ + R++ Q Sbjct: 750 KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 809 Query: 570 QEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNG 629 QEE ++R E + +++ K + E+ +E + K + +++ + E+RL++E + Sbjct: 810 QEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 867 Query: 630 TLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLK 678 L + K+L ++ +++QQ+ E L R ++++ ++ +K Sbjct: 868 RLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 916 Score = 39.3 bits (90), Expect = 0.012 Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 49/197 (24%) Query: 508 PLVSKISEKRKKKLRLLEQQ----ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRK 563 P + ++ + K K LEQ+ E+R K EEEE + + EE+R+ Sbjct: 715 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ-----------------EELRR 757 Query: 564 QRRLL---QQEEKVKRQE-------------RLKEDQQTVLKPQFYE---------IKAG 598 Q+ + QQEE+ KR+E R + +Q+ L+ Q E ++ Sbjct: 758 QQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 817 Query: 599 EEFRSFKDSATKQ-KLMNKTLEDRLK--IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655 EE R ++ KQ +L+ K E+ K E + + + + ++ L+ E+++K Sbjct: 818 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 877 Query: 656 QQEAEKLHRQERKRLRR 672 ++E E ++E R R+ Sbjct: 878 RKELEVQRQKELMRQRQ 894 >gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens] Length = 1320 Score = 61.2 bits (147), Expect = 3e-09 Identities = 59/251 (23%), Positives = 125/251 (49%), Gaps = 20/251 (7%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 +E R+ ++R K EE +R + +L + +E+ L+ +EEE K++ + + L Sbjct: 760 QERREAEMRAKREEEERKRQE--ELRRQQEEI-LRRQQEEERKRREEEELARRKQEEALR 816 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541 R + + + E EE + + ++ E+R+++ +Q+EL K+EEE + Sbjct: 817 RQREQEIA----LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 872 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601 + E+ ++ + +EE + RL +EE+ KR+E + Q+ +++ + + E Sbjct: 873 REEEEAQRRLEENRLRMEE--EAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEAL 927 Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661 R + +Q+L ++K+ + + S+TT Q T +L +E QK ++E E+ Sbjct: 928 RRLQQQQQQQQLA------QMKLPSSSTWGQQSNTTACQSQATLSL--AEIQKLEEERER 979 Query: 662 LHRQERKRLRR 672 R+E++R +R Sbjct: 980 QLREEQRRQQR 990 Score = 52.8 bits (125), Expect = 1e-06 Identities = 37/169 (21%), Positives = 82/169 (48%), Gaps = 8/169 (4%) Query: 516 KRKKKLR------LLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQ 569 KR+++LR L QQE K EEE + E+ +++ + R++ Q Sbjct: 777 KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 836 Query: 570 QEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNG 629 QEE ++R E + +++ K + E+ +E + K + +++ + E+RL++E + Sbjct: 837 QEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 894 Query: 630 TLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLK 678 L + K+L ++ +++QQ+ E L R ++++ ++ +K Sbjct: 895 RLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 943 Score = 39.3 bits (90), Expect = 0.012 Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 49/197 (24%) Query: 508 PLVSKISEKRKKKLRLLEQQ----ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRK 563 P + ++ + K K LEQ+ E+R K EEEE + + EE+R+ Sbjct: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ-----------------EELRR 784 Query: 564 QRRLL---QQEEKVKRQE-------------RLKEDQQTVLKPQFYE---------IKAG 598 Q+ + QQEE+ KR+E R + +Q+ L+ Q E ++ Sbjct: 785 QQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 844 Query: 599 EEFRSFKDSATKQ-KLMNKTLEDRLK--IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655 EE R ++ KQ +L+ K E+ K E + + + + ++ L+ E+++K Sbjct: 845 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 904 Query: 656 QQEAEKLHRQERKRLRR 672 ++E E ++E R R+ Sbjct: 905 RKELEVQRQKELMRQRQ 921 >gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 61.2 bits (147), Expect = 3e-09 Identities = 59/251 (23%), Positives = 125/251 (49%), Gaps = 20/251 (7%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 +E R+ ++R K EE +R + +L + +E+ L+ +EEE K++ + + L Sbjct: 739 QERREAEMRAKREEEERKRQE--ELRRQQEEI-LRRQQEEERKRREEEELARRKQEEALR 795 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541 R + + + E EE + + ++ E+R+++ +Q+EL K+EEE + Sbjct: 796 RQREQEIA----LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 851 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601 + E+ ++ + +EE + RL +EE+ KR+E + Q+ +++ + + E Sbjct: 852 REEEEAQRRLEENRLRMEE--EAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEAL 906 Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661 R + +Q+L ++K+ + + S+TT Q T +L +E QK ++E E+ Sbjct: 907 RRLQQQQQQQQLA------QMKLPSSSTWGQQSNTTACQSQATLSL--AEIQKLEEERER 958 Query: 662 LHRQERKRLRR 672 R+E++R +R Sbjct: 959 QLREEQRRQQR 969 Score = 52.8 bits (125), Expect = 1e-06 Identities = 37/169 (21%), Positives = 82/169 (48%), Gaps = 8/169 (4%) Query: 516 KRKKKLR------LLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQ 569 KR+++LR L QQE K EEE + E+ +++ + R++ Q Sbjct: 756 KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 815 Query: 570 QEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNG 629 QEE ++R E + +++ K + E+ +E + K + +++ + E+RL++E + Sbjct: 816 QEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 873 Query: 630 TLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLK 678 L + K+L ++ +++QQ+ E L R ++++ ++ +K Sbjct: 874 RLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922 Score = 39.3 bits (90), Expect = 0.012 Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 49/197 (24%) Query: 508 PLVSKISEKRKKKLRLLEQQ----ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRK 563 P + ++ + K K LEQ+ E+R K EEEE + + EE+R+ Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ-----------------EELRR 763 Query: 564 QRRLL---QQEEKVKRQE-------------RLKEDQQTVLKPQFYE---------IKAG 598 Q+ + QQEE+ KR+E R + +Q+ L+ Q E ++ Sbjct: 764 QQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 823 Query: 599 EEFRSFKDSATKQ-KLMNKTLEDRLK--IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655 EE R ++ KQ +L+ K E+ K E + + + + ++ L+ E+++K Sbjct: 824 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 883 Query: 656 QQEAEKLHRQERKRLRR 672 ++E E ++E R R+ Sbjct: 884 RKELEVQRQKELMRQRQ 900 >gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 61.2 bits (147), Expect = 3e-09 Identities = 59/251 (23%), Positives = 125/251 (49%), Gaps = 20/251 (7%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 +E R+ ++R K EE +R + +L + +E+ L+ +EEE K++ + + L Sbjct: 739 QERREAEMRAKREEEERKRQE--ELRRQQEEI-LRRQQEEERKRREEEELARRKQEEALR 795 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541 R + + + E EE + + ++ E+R+++ +Q+EL K+EEE + Sbjct: 796 RQREQEIA----LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 851 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601 + E+ ++ + +EE + RL +EE+ KR+E + Q+ +++ + + E Sbjct: 852 REEEEAQRRLEENRLRMEE--EAARLRHEEEERKRKELEVQRQKELMRQRQQQ---QEAL 906 Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661 R + +Q+L ++K+ + + S+TT Q T +L +E QK ++E E+ Sbjct: 907 RRLQQQQQQQQLA------QMKLPSSSTWGQQSNTTACQSQATLSL--AEIQKLEEERER 958 Query: 662 LHRQERKRLRR 672 R+E++R +R Sbjct: 959 QLREEQRRQQR 969 Score = 52.8 bits (125), Expect = 1e-06 Identities = 37/169 (21%), Positives = 82/169 (48%), Gaps = 8/169 (4%) Query: 516 KRKKKLR------LLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQ 569 KR+++LR L QQE K EEE + E+ +++ + R++ Q Sbjct: 756 KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 815 Query: 570 QEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNG 629 QEE ++R E + +++ K + E+ +E + K + +++ + E+RL++E + Sbjct: 816 QEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA 873 Query: 630 TLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLK 678 L + K+L ++ +++QQ+ E L R ++++ ++ +K Sbjct: 874 RLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMK 922 Score = 39.3 bits (90), Expect = 0.012 Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 49/197 (24%) Query: 508 PLVSKISEKRKKKLRLLEQQ----ELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRK 563 P + ++ + K K LEQ+ E+R K EEEE + + EE+R+ Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQ-----------------EELRR 763 Query: 564 QRRLL---QQEEKVKRQE-------------RLKEDQQTVLKPQFYE---------IKAG 598 Q+ + QQEE+ KR+E R + +Q+ L+ Q E ++ Sbjct: 764 QQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRL 823 Query: 599 EEFRSFKDSATKQ-KLMNKTLEDRLK--IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655 EE R ++ KQ +L+ K E+ K E + + + + ++ L+ E+++K Sbjct: 824 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 883 Query: 656 QQEAEKLHRQERKRLRR 672 ++E E ++E R R+ Sbjct: 884 RKELEVQRQKELMRQRQ 900 >gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] Length = 495 Score = 60.1 bits (144), Expect = 7e-09 Identities = 63/254 (24%), Positives = 127/254 (50%), Gaps = 25/254 (9%) Query: 420 AYEEYRKDKIR-QKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPN 478 AYE+ K+K+ +I + QL+K K+ K A++ EE +K+++ W+KK + Sbjct: 205 AYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKRE--E 262 Query: 479 ILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEP 538 + ++R + F N + ++ EE R+ +K+ E +K+L+L Q L +K EE Sbjct: 263 MEEENRKIIEFAN----MQQQREEDRM-----AKVQENEEKRLQL--QNALTQKLEEMLR 311 Query: 539 EGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED--QQTVLKPQFYEIK 596 + + + E +E+A E+ K + + E+K+++Q+ +K+D +Q LK + Sbjct: 312 QREDLEQVRQELYQEEQA---EIYKSKLKEEAEKKLRKQKEMKQDFEEQMALKELVLQ-A 367 Query: 597 AGEEFRSFKDSATKQKLMNKTLEDRLKI-EAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655 A EE +F+ K L +DR+++ A+ + + ++L ++ K Sbjct: 368 AKEEEENFR----KTMLAKFAEDDRIELMNAQKQRMKQLEHRRAVEKLIEERRQQFLADK 423 Query: 656 QQEAEKLHRQERKR 669 Q+E E+ Q+R++ Sbjct: 424 QRELEEWQLQQRRQ 437 Score = 45.1 bits (105), Expect = 2e-04 Identities = 44/260 (16%), Positives = 120/260 (46%), Gaps = 47/260 (18%) Query: 427 DKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFK 486 ++ ++ ++E +++ ++ L VN ++ ++++ E + + K +L +++F+ Sbjct: 12 ERHQKLVDENYCKKLHVQALKNVNSQIRNQMVQNENDNRVQR-----KQFLRLLQNEQFE 66 Query: 487 VMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKE----------EEE 536 + E + +++EE + L L K EK +L L+ + L++++ E Sbjct: 67 LDME----EAIQKAEENKRLKELQLKQEEKLAMELAKLKHESLKDEKMRQQVRENSIELR 122 Query: 537 EPEGKPSDA-----ESSESSDDEKAWVEEVRKQ----RRLLQQEEKVKRQERLKEDQQTV 587 E E K A +++ ++ + E++++ + ++++ +++ ++E ED++ Sbjct: 123 ELEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKEENAAEDKRNK 182 Query: 588 LKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTL 647 K Q+Y E + + KQ+ + L+++L I+ ++ + Sbjct: 183 AKAQYY---LDLEKQLEEQEKKKQEAYEQLLKEKLMID----------------EIVRKI 223 Query: 648 KRSEQQKKQQEAEKLHRQER 667 +Q +KQQ+ EK++ R Sbjct: 224 YEEDQLEKQQKLEKMNAMRR 243 Score = 37.7 bits (86), Expect = 0.036 Identities = 54/260 (20%), Positives = 111/260 (42%), Gaps = 36/260 (13%) Query: 421 YEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL 480 +E ++ I++ E R + +QLK+ K+ ELA KL E + +K + + S+ Sbjct: 65 FELDMEEAIQKAEENKRLKELQLKQEEKLAMELA-KLKHESLKDEKMRQQVRENSIELRE 123 Query: 481 TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540 + + K + N E + + + + + ++ + + + ++ R +EE E Sbjct: 124 LEKKLKAAYMN-----KERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKEENAAED 178 Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQ--EEKVKRQE---RLKEDQQTVLKPQFYEI 595 K + A++ D EK E+ +K++ +Q +EK+ E ++ E+ Q + + ++ Sbjct: 179 KRNKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKM 238 Query: 596 KAG----EEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSE 651 A EEF+ + K+K E+R IE N + Sbjct: 239 NAMRRYIEEFQKEQALWRKKKREEMEEENRKIIEFAN---------------------MQ 277 Query: 652 QQKKQQEAEKLHRQERKRLR 671 QQ+++ K+ E KRL+ Sbjct: 278 QQREEDRMAKVQENEEKRLQ 297 Score = 37.4 bits (85), Expect = 0.047 Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 19/127 (14%) Query: 421 YEEYRKDKIRQKIEETRAQRVQLKKLPKVN-------KELALKLIEEEEEKQKSTWKKKV 473 Y+E + + + K++E ++++ +K K + KEL L+ +EEEE + T Sbjct: 324 YQEEQAEIYKSKLKEEAEKKLRKQKEMKQDFEEQMALKELVLQAAKEEEENFRKTM---- 379 Query: 474 KSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKE 533 L DDR ++M N Q ++ E R V K+ E+R+++ +Q+EL E + Sbjct: 380 --LAKFAEDDRIELM--NAQKQRMKQLEHRRA----VEKLIEERRQQFLADKQRELEEWQ 431 Query: 534 EEEEPEG 540 ++ +G Sbjct: 432 LQQRRQG 438 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 59.3 bits (142), Expect = 1e-08 Identities = 65/249 (26%), Positives = 112/249 (44%), Gaps = 39/249 (15%) Query: 427 DKIRQKIEETRAQRVQLKKLPKVNKELALKLIEE---EEEKQKSTWKKKVKSLPNILTDD 483 +K+R+ I + + KL + + E+ L EE EEE+ K++ + D Sbjct: 2148 NKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGD 2207 Query: 484 RFKVMFENPDFQVDE-ESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542 + K F + QVDE ESEE SE+ + L LE+QE EEEEE E + Sbjct: 2208 KPKEKFSS---QVDEVESEEH---------FSEEMESLLDELEKQESLSSEEEEEREEEE 2255 Query: 543 SDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFR 602 E ++E+ EE +++++ ++EE+ K++++ K+ ++ K + +E K EE Sbjct: 2256 EREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK--EEIM 2313 Query: 603 SFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKL 662 S E + +LS + S L + R ++ K+++ KL Sbjct: 2314 S---------------------EEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKL 2352 Query: 663 HRQERKRLR 671 Q RK LR Sbjct: 2353 QEQRRKSLR 2361 Score = 47.0 bits (110), Expect = 6e-05 Identities = 63/297 (21%), Positives = 131/297 (44%), Gaps = 53/297 (17%) Query: 422 EEYRKDKIRQKIEETRAQRVQL-KKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNIL 480 EE++ +I +K +R Q +KL + ++LA +EE + +K ++ I Sbjct: 1570 EEHKWARIHRKRARAEKKRAQEERKLAQEEEKLA-----QEERQLAQEERKLAQAYVKIT 1624 Query: 481 TDDRFKVMFENPDFQVDEE-SEEFRLLNPLVSKISEKRKK-------------KL----- 521 DDR E Q +E ++ L+ K+++KRKK KL Sbjct: 1625 QDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGG 1684 Query: 522 RLLEQQELREKEEEEEPEGKPS----------DAESSESSDDEKAWVEE---------VR 562 +L E + + ++ EE P+ + + + E E +E +W EE V Sbjct: 1685 KLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVE 1744 Query: 563 KQRRLLQQEEKVK-RQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQ-----KLMNK 616 ++++L ++EE + ++E+L E++ + + + I+ E+ K+ ++ + + Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQ 1804 Query: 617 TLEDRLKIEAKNGT-LSVSDTTVGSKQLTFTLKRSEQQKKQ--QEAEKLHRQERKRL 670 +E ++K+ K ++ + +K + + K Q+KK QE EKL +++ L Sbjct: 1805 LIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLL 1861 Score = 47.0 bits (110), Expect = 6e-05 Identities = 67/292 (22%), Positives = 125/292 (42%), Gaps = 52/292 (17%) Query: 430 RQKIEETRAQRVQLK-KLPKVNKELAL---KLIEEEE------EKQKSTWKKKVKSLPNI 479 ++++ ++ Q VQ+K KL NK LA KL +E+E EK T KK V+ ++ Sbjct: 1864 KERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSL 1923 Query: 480 ------LTDDRFKVMFENPDFQVDEE-------SEEFRLLNPLVSKISEKRKKKLRLLEQ 526 L ++ K+ E Q + ++E + LN + +++E +K+RL+E Sbjct: 1924 AKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAE---EKMRLVEG 1980 Query: 527 QELREKEEEEEPEGKPSDAESSESSDDEKAWVEE--VRKQRRLLQQEEK--VKRQERLKE 582 +E K E E + + + + K +EE + + R+L EE K + Sbjct: 1981 KETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTR 2040 Query: 583 DQQTVLKPQFYEIKAGEEFRSFKDSATKQ--------KLMNKTLEDRLKIE--------- 625 Q+ ++ Q KA + ++S +K+ K + K D K+ Sbjct: 2041 GQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKM 2100 Query: 626 -----AKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRR 672 K LS+ + + K+ F+ KRSE K +++ + R+ ++RR Sbjct: 2101 KRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRR 2152 Score = 45.8 bits (107), Expect = 1e-04 Identities = 60/272 (22%), Positives = 118/272 (43%), Gaps = 42/272 (15%) Query: 432 KIEETRAQRVQL---KKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRF--- 485 K+E TR QR+ + +KL K +++L K E K+ + K +K+L + D+R Sbjct: 2035 KLEFTRGQRIFVQGQRKLAKASRKLIKK--RESLSKEPAKLNKILKALQKLTRDERKLTQ 2092 Query: 486 -----------------KVMFENPDFQVDEE--SEEFRLLNPLVSKISEKRKK---KLRL 523 ++ E + E SE+ L K++ K++K K+R Sbjct: 2093 EEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRR 2152 Query: 524 LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEE---VRKQRRLLQQEEKVKRQERL 580 + +E + EEE + K S+ D+E+ +EE + +R ++ ++ KR ++ Sbjct: 2153 MINKEEKMTEEESKLARKHSEVILD---DEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKP 2209 Query: 581 KEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGS 640 KE + + E EE S D KQ+ ++ E+ + E + V + Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269 Query: 641 KQLTFTLKRSEQQKKQQEAEKLHRQERKRLRR 672 K+ E ++KQ E E+ ++++K+ ++ Sbjct: 2270 KE------EEEGEEKQVEKEEEEKKKKKKEKK 2295 Score = 44.3 bits (103), Expect = 4e-04 Identities = 75/285 (26%), Positives = 128/285 (44%), Gaps = 39/285 (13%) Query: 422 EEYRKDKIRQKI--EETRAQRVQLKKLPKV------NKELALKLIEEEEEK--QKSTWKK 471 EE + K R + EET+ V LKK KV N + ++ ++EE+K QKS K+ Sbjct: 1347 EEQAQKKARDMLGLEETQ---VILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSP-KQ 1402 Query: 472 KVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELRE 531 K++ + K + + EE EE L V K ++ KL ++E+ + Sbjct: 1403 GRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVK----QEGKLVMIERTPSWQ 1458 Query: 532 KEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKR--------QERLKED 583 ++ E K E+ +S KAW EE K RLLQ+EEK+ + +E L+ED Sbjct: 1459 DWKKAWDEWKQVHGETRKSW---KAWKEEWEK--RLLQEEEKLHQAGEKLSPEEEMLQED 1513 Query: 584 QQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNK-TLEDRLKIEAKNGTLSVSDTT----V 638 ++ LK + ++ + E S K + K + TLE+ + E + V++ Sbjct: 1514 KK--LKWEEWK-QVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQE 1570 Query: 639 GSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683 K KR+ +KK+ + E+ QE ++L + L ++ Sbjct: 1571 EHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERK 1615 Score = 41.6 bits (96), Expect = 0.002 Identities = 40/177 (22%), Positives = 86/177 (48%), Gaps = 24/177 (13%) Query: 426 KDKIRQKIEETRAQRVQLKKLPKVNKELALK--LIEEEEEKQKSTWKKKVKSLPNILTDD 483 K+K +++E ++ +++ + EL + L EEEE+++ +++ + Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEE--------- 2260 Query: 484 RFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPS 543 +V E + + +EE EE + V K E++KKK ++ ++KEE +E E Sbjct: 2261 --EVREEEEERKEEEEGEEKQ-----VEKEEEEKKKK------KKEKKKEEVQEKEEVFE 2307 Query: 544 DAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600 + E S ++ ++ +E ++ +EE + +E LK+++Q L+ Q + G E Sbjct: 2308 EKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRE 2364 Score = 37.7 bits (86), Expect = 0.036 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 55/224 (24%) Query: 466 KSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEES--EEFRLL--NPLVSKISEKRKKKL 521 K W+K++ L K+ E Q D++ EE++ + N L SK E++ K Sbjct: 1482 KEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDE 1541 Query: 522 R--LLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRK-----------QRRLL 568 LE++ RE EE+E+ E +E W RK +R+L Sbjct: 1542 EEVTLEEEVSREGEEKEQQV-----TEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLA 1596 Query: 569 QQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKN 628 Q+EEK+ ++ER ++ L + +I T +DR +A+ Sbjct: 1597 QEEEKLAQEERQLAQEERKLAQAYVKI---------------------TQDDREMAQAE- 1634 Query: 629 GTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRR 672 G + + T+ + +K QEAEKL Q+RK+L + Sbjct: 1635 GKFAQKEETLAQR----------GEKLSQEAEKL-AQKRKKLAK 1667 Score = 35.8 bits (81), Expect = 0.14 Identities = 31/118 (26%), Positives = 63/118 (53%), Gaps = 7/118 (5%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 EE R+++ ++ EE R + + K+ + ++ K EE+++K+K K++V+ + Sbjct: 2248 EEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVF- 2306 Query: 482 DDRFKVMF--ENPDFQVDEESEEFRLLNPLVSKISE--KRKKKLRLLEQ--QELREKE 533 +++ ++M E +EE EE L V + E K++K+ +L EQ + LR +E Sbjct: 2307 EEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRE 2364 Score = 35.0 bits (79), Expect = 0.23 Identities = 51/254 (20%), Positives = 116/254 (45%), Gaps = 28/254 (11%) Query: 433 IEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKK--VKSLPNILTDDRFKVMFE 490 I+E +K+P+ + L K + E+K K K++ + S+ LT ++ + Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEE-LTKNKMIL--- 1833 Query: 491 NPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSES 550 +Q ++E + L K+++ RK+ L +++ K++ + + K + Sbjct: 1834 ---YQKKNLAQEKKNLAQEKEKLAQ-RKENLLYNKERLTHSKKQLVQVKNKLGMFNKILA 1889 Query: 551 SDDEKAWVEE---VRKQRRLLQQEEKV--------KRQERLKEDQQTVLKPQFYEIKAGE 599 +EK E+ ++K+ +L + E+K+ K+QE+L +++ + + ++ + Sbjct: 1890 QVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAM-VQGKK 1948 Query: 600 EFRSFKDSATKQKLMN----KTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSE--QQ 653 R D A ++K +N + E+++++ TLS +T S+Q T E ++ Sbjct: 1949 RLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFER 2008 Query: 654 KKQQEAEKLHRQER 667 K E + L ++R Sbjct: 2009 KLSLEEKILLHEDR 2022 >gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform 1 [Homo sapiens] Length = 1722 Score = 58.9 bits (141), Expect = 1e-08 Identities = 60/248 (24%), Positives = 120/248 (48%), Gaps = 20/248 (8%) Query: 425 RKDKIRQKIEETR-----AQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNI 479 R++K Q+ EE R +V+ KKL + K+ K+ +E K++ WK+K K Sbjct: 195 REEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKM-NDELYKEEKIWKEKFKQHEEY 253 Query: 480 LTDDRFKVMFENPDFQVDEESEEFRLL---NPLVSKISEKRK------KKLRLLEQQELR 530 + + ++ E F+ +E E+ LL N KI K K K ++++Q Sbjct: 254 IRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIES 313 Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKP 590 +K + +E + K + E + ++ E+ K+ R Q+EE+ KR+E+ E+++ ++K Sbjct: 314 KKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQ 373 Query: 591 QFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRS 650 + ++ + E+ ++ A++Q +++ L+ K N LS+ D + + L Sbjct: 374 EREQLISKEKI-ILREDASQQLIISSALK---KSGYNNKHLSLEDISNDKGDIAKNLV-D 428 Query: 651 EQQKKQQE 658 E KKQ++ Sbjct: 429 ENSKKQED 436 Score = 43.9 bits (102), Expect = 5e-04 Identities = 46/235 (19%), Positives = 109/235 (46%), Gaps = 29/235 (12%) Query: 458 IEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKR 517 +EE+ + W++K K L +D+ K + Q D E ++F+ E+ Sbjct: 163 VEEKCRQSFEAWQEKQKEL-----EDKEKQTLKA---QRDREEKQFQ----------EEE 204 Query: 518 KKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQR------RLLQQE 571 +K+ ++Q ++ EK++ E + + D + E +EK W E+ ++ L +E Sbjct: 205 EKRHCWMKQFKV-EKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEE 263 Query: 572 EKVKRQERLKEDQQTVLKPQ-FYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGT 630 E+ + +++ ++++ ++LK Q +K ++++F ++ + +E + + K Sbjct: 264 ERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESK---KRKAQE 320 Query: 631 LSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 + + K+ + E+Q+ ++E +K +ERKR + K+ K+ R Sbjct: 321 WKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQER 375 Score = 42.0 bits (97), Expect = 0.002 Identities = 62/279 (22%), Positives = 128/279 (45%), Gaps = 38/279 (13%) Query: 425 RKDKIRQKIEETRA---QRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPN--- 478 ++ KIRQK EE R + ++K+ K KE K E+E E++K+ K++ + L + Sbjct: 324 KEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEK 383 Query: 479 -ILTDDRFKVM----------FENPDFQVDEES-EEFRLLNPLVSKISEKRKKKLR-LLE 525 IL +D + + + N +++ S ++ + LV + S+K++ L L+E Sbjct: 384 IILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVE 443 Query: 526 QQELREKEE-----EEEPEGKPSDAESSES------SDDEKAWVEEVRKQRRLLQQEEKV 574 + ++E + +E + K ++ SS++ +++ + + R L++QE K Sbjct: 444 ESNMKENVDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQERKY 503 Query: 575 KRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAK---NGTL 631 + + E + LK E +E +S D+ ++K+M + + + + Sbjct: 504 ENTDNKTELGNSDLKGNLKEQFPLQELKS--DAQKEEKIMKHVINENTGQKTQIILGHNQ 561 Query: 632 SVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRL 670 +S+ +Q + + QQKK Q+ EK QE+ L Sbjct: 562 EISEVKTNEEQ---KIIKDNQQKKIQKVEKEEIQEQNGL 597 Score = 30.4 bits (67), Expect = 5.7 Identities = 44/192 (22%), Positives = 76/192 (39%), Gaps = 40/192 (20%) Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQ------------- 577 E EE+ + + E D EK ++ R + QEE+ KR Sbjct: 162 EVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKL 221 Query: 578 ERLKEDQQTVLKPQFYE--------------------IKAGEEFRSFKDSATKQK--LMN 615 E +++ +Q + + Y+ ++ EE FKD K+K L+ Sbjct: 222 ENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLK 281 Query: 616 KTLEDRLKIEAKNGTLSVSDTTVGS--KQLTFTLKRSEQQKKQQEAEKLHRQE--RKRLR 671 + +KI+AK V+ G K+ + KR Q+ K++EA+ ++E RKRL Sbjct: 282 QQNNAAVKIQAKYKAF-VAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLE 340 Query: 672 RSAGHLKSRHKR 683 + R K+ Sbjct: 341 EEQRIKEERKKQ 352 >gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform 2 [Homo sapiens] Length = 1336 Score = 58.9 bits (141), Expect = 1e-08 Identities = 60/248 (24%), Positives = 120/248 (48%), Gaps = 20/248 (8%) Query: 425 RKDKIRQKIEETR-----AQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNI 479 R++K Q+ EE R +V+ KKL + K+ K+ +E K++ WK+K K Sbjct: 195 REEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKM-NDELYKEEKIWKEKFKQHEEY 253 Query: 480 LTDDRFKVMFENPDFQVDEESEEFRLL---NPLVSKISEKRK------KKLRLLEQQELR 530 + + ++ E F+ +E E+ LL N KI K K K ++++Q Sbjct: 254 IRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIES 313 Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKP 590 +K + +E + K + E + ++ E+ K+ R Q+EE+ KR+E+ E+++ ++K Sbjct: 314 KKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQ 373 Query: 591 QFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRS 650 + ++ + E+ ++ A++Q +++ L+ K N LS+ D + + L Sbjct: 374 EREQLISKEKI-ILREDASQQLIISSALK---KSGYNNKHLSLEDISNDKGDIAKNLV-D 428 Query: 651 EQQKKQQE 658 E KKQ++ Sbjct: 429 ENSKKQED 436 Score = 43.9 bits (102), Expect = 5e-04 Identities = 46/235 (19%), Positives = 109/235 (46%), Gaps = 29/235 (12%) Query: 458 IEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKR 517 +EE+ + W++K K L +D+ K + Q D E ++F+ E+ Sbjct: 163 VEEKCRQSFEAWQEKQKEL-----EDKEKQTLKA---QRDREEKQFQ----------EEE 204 Query: 518 KKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQR------RLLQQE 571 +K+ ++Q ++ EK++ E + + D + E +EK W E+ ++ L +E Sbjct: 205 EKRHCWMKQFKV-EKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEE 263 Query: 572 EKVKRQERLKEDQQTVLKPQ-FYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGT 630 E+ + +++ ++++ ++LK Q +K ++++F ++ + +E + + K Sbjct: 264 ERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESK---KRKAQE 320 Query: 631 LSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 + + K+ + E+Q+ ++E +K +ERKR + K+ K+ R Sbjct: 321 WKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQER 375 Score = 42.0 bits (97), Expect = 0.002 Identities = 62/279 (22%), Positives = 128/279 (45%), Gaps = 38/279 (13%) Query: 425 RKDKIRQKIEETRA---QRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPN--- 478 ++ KIRQK EE R + ++K+ K KE K E+E E++K+ K++ + L + Sbjct: 324 KEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEK 383 Query: 479 -ILTDDRFKVM----------FENPDFQVDEES-EEFRLLNPLVSKISEKRKKKLR-LLE 525 IL +D + + + N +++ S ++ + LV + S+K++ L L+E Sbjct: 384 IILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVE 443 Query: 526 QQELREKEE-----EEEPEGKPSDAESSES------SDDEKAWVEEVRKQRRLLQQEEKV 574 + ++E + +E + K ++ SS++ +++ + + R L++QE K Sbjct: 444 ESNMKENVDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQERKY 503 Query: 575 KRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAK---NGTL 631 + + E + LK E +E +S D+ ++K+M + + + + Sbjct: 504 ENTDNKTELGNSDLKGNLKEQFPLQELKS--DAQKEEKIMKHVINENTGQKTQIILGHNQ 561 Query: 632 SVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRL 670 +S+ +Q + + QQKK Q+ EK QE+ L Sbjct: 562 EISEVKTNEEQ---KIIKDNQQKKIQKVEKEEIQEQNGL 597 Score = 30.4 bits (67), Expect = 5.7 Identities = 44/192 (22%), Positives = 76/192 (39%), Gaps = 40/192 (20%) Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQ------------- 577 E EE+ + + E D EK ++ R + QEE+ KR Sbjct: 162 EVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKL 221 Query: 578 ERLKEDQQTVLKPQFYE--------------------IKAGEEFRSFKDSATKQK--LMN 615 E +++ +Q + + Y+ ++ EE FKD K+K L+ Sbjct: 222 ENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLK 281 Query: 616 KTLEDRLKIEAKNGTLSVSDTTVGS--KQLTFTLKRSEQQKKQQEAEKLHRQE--RKRLR 671 + +KI+AK V+ G K+ + KR Q+ K++EA+ ++E RKRL Sbjct: 282 QQNNAAVKIQAKYKAF-VAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLE 340 Query: 672 RSAGHLKSRHKR 683 + R K+ Sbjct: 341 EEQRIKEERKKQ 352 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 58.2 bits (139), Expect = 3e-08 Identities = 56/282 (19%), Positives = 138/282 (48%), Gaps = 31/282 (10%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE----------EKQKSTWKK--K 472 +++KIR++ E+ R Q ++++ ++ E K+ +EE +++ W+K K Sbjct: 380 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439 Query: 473 VKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE-LRE 531 ++ L + + K+ + Q +E+ E +K+ + +K + EQ+E +RE Sbjct: 440 IRELEEKMHEQE-KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK---IREQEEKIRE 495 Query: 532 KEE-----EEEPEGKPSDAESSESSDDEKAWVEE--VRKQRRLLQQEEKVKRQE-RLKED 583 +EE EE+ + E + + E+ W +E +R+Q + +Q+EK+ QE ++++ Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555 Query: 584 QQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQL 643 ++ + + + E+ R ++ +Q+ + E++++ E + + T ++ Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR-EQEEKIREQEEMTQEQEE- 613 Query: 644 TFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 K EQ++K E E+ +++ +++RR ++ + K+ R Sbjct: 614 ----KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651 Score = 57.4 bits (137), Expect = 4e-08 Identities = 56/264 (21%), Positives = 128/264 (48%), Gaps = 32/264 (12%) Query: 425 RKDKIRQKIEETRAQRVQL-KKLPKVNKELALKLIEEEEEKQKSTWKK--KVKSLPNILT 481 +++KIR++ E+ R Q ++ ++ K++++ ++ EE+ ++Q+ W++ K++ I Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE-EEKRQEQEEMWRQEEKIREQEEIWR 540 Query: 482 DDRFKVMFENPDFQVDEES--EEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE-EEP 538 K+ + + EE + ++ KI E+ +K R +++++RE+EE+ E Sbjct: 541 QKE-KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWR--QEEKIREQEEKIREQ 597 Query: 539 EGKPSDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEI 595 E K + E +EK +E + ++ ++ +QEEK++RQE +Q+ ++ Q +I Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657 Query: 596 KAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655 + EE ++ ++ K E K++ + K Q++K Sbjct: 658 REQEEMMQEQEEKMWEQ-EEKMCEQEEKMQEQEE------------------KMRRQEEK 698 Query: 656 QQEAEKLHRQERKRLRRSAGHLKS 679 E E RQ+ ++++ HL++ Sbjct: 699 MWEQEVRLRQQEEKMQEHQEHLEA 722 Score = 51.2 bits (121), Expect = 3e-06 Identities = 56/283 (19%), Positives = 125/283 (44%), Gaps = 59/283 (20%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKK--KVKSLPNILTD 482 +++KIR+ E+ Q ++ K +E ++ E+ +E++ W++ K++ + + Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495 Query: 483 DRFKV------MFENPDFQVDEESEEFRLLNPLVSKISEKR---KKKLRLLEQQELREKE 533 K+ + E + +E+ +E + KI E+ ++K ++ EQ+E K+ Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555 Query: 534 EEE--EPEGKPSDAESSESSDDEKAWVEEVR---KQRRLLQQEEKVKRQE---------- 578 EE+ E K D E +EK W +E + ++ ++ +QEEK++ QE Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615 Query: 579 ------------RLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEA 626 +++E ++ + + + + ++ R ++ +Q+ M + E+++ + Sbjct: 616 GEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675 Query: 627 KNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQE-AEKLHRQERK 668 + K EQ++K QE EK+ RQE K Sbjct: 676 E--------------------KMCEQEEKMQEQEEKMRRQEEK 698 Score = 49.3 bits (116), Expect = 1e-05 Identities = 59/277 (21%), Positives = 117/277 (42%), Gaps = 42/277 (15%) Query: 425 RKDKIRQKIEETRAQR----VQLKKLPKVNKELALKLIEEEE-----EKQKSTWKKKVKS 475 +K K + IEE +R ++L + ++EL K + +E E +KS + VK Sbjct: 248 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 307 Query: 476 LPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE 535 L L + + + + D +E + ++ + E+ + RL +QQE + +E Sbjct: 308 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 367 Query: 536 E-----------------EPEGKPSDAESSESSDDEKAWVEEVRKQRR---LLQQEEKVK 575 E E E K + E +E W +E + +R+ + ++EEK++ Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 427 Query: 576 RQERL---KEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLS 632 RQE + KE++ L+ + +E + E + K + K E K+ + + Sbjct: 428 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 487 Query: 633 VSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKR 669 + + R +++K ++ EK+H QE+ R Sbjct: 488 EQEEKI----------REQEEKMWRQEEKIHEQEKIR 514 Score = 47.8 bits (112), Expect = 3e-05 Identities = 46/196 (23%), Positives = 97/196 (49%), Gaps = 26/196 (13%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEK----QKSTWKKKVKSLP 477 E+ R+++ RQ+ EE Q ++++ ++ ++ + I E+EEK ++ W+++ K Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQK--EKIHEQEEKIRKQEEKMWRQEEK--- 565 Query: 478 NILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE- 536 + D K+ + +V + E+ R + + EK +++ + ++QE + E+EE Sbjct: 566 --MHDQEEKI--REQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 621 Query: 537 --EPEGKPSDAESSESSDDEKAWVEE---------VRKQRRLLQ-QEEKVKRQERLKEDQ 584 E E K + E +EK +E +R+Q ++Q QEEK+ QE +Q Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 681 Query: 585 QTVLKPQFYEIKAGEE 600 + ++ Q +++ EE Sbjct: 682 EEKMQEQEEKMRRQEE 697 Score = 34.7 bits (78), Expect = 0.30 Identities = 30/134 (22%), Positives = 64/134 (47%), Gaps = 10/134 (7%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWK-----KKVKSLPNI 479 +++KIR++ E+ R Q ++ + E K+ E+EE+ Q+ K +K++ Sbjct: 590 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK 649 Query: 480 LTDDRFKVMFENPDFQVDEES--EEFRLLNPLVSKISEKRKKKLRLLE---QQELREKEE 534 + + K+ + Q EE E+ + K+ E+ +K R E +QE+R +++ Sbjct: 650 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709 Query: 535 EEEPEGKPSDAESS 548 EE+ + E++ Sbjct: 710 EEKMQEHQEHLEAA 723 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 57.8 bits (138), Expect = 3e-08 Identities = 57/260 (21%), Positives = 119/260 (45%), Gaps = 16/260 (6%) Query: 436 TRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKK-VKSLPNILTDDRFKVMFENPDF 494 T A R +K K N L + E+E ++ ++ +K+ + L ++ + E Sbjct: 509 TSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL 568 Query: 495 QVDEESEEFRLLNPLVSKISEKRKK----KLRLLEQQELREKEEE--EEPEGKPSDAESS 548 + +E + V ++ E++KK K ++++ + KEE EE K + A+ Sbjct: 569 KREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 628 Query: 549 ESSDDEKAWVEEVRKQRRLLQQEEKVKRQERL---KEDQQTVLKPQFYEIKAGEEFRSFK 605 E + + EE R+ R L Q+EE+ + QE L KE++Q L+ KA E R + Sbjct: 629 EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLR------KAAEAKRLAE 682 Query: 606 DSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQ 665 +++ + ++R + E + + + ++ +R + +++ QE EK R Sbjct: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 742 Query: 666 ERKRLRRSAGHLKSRHKRGR 685 ++++L+R K + ++ R Sbjct: 743 QKEQLQRELEEKKKKEEQQR 762 Score = 56.6 bits (135), Expect = 7e-08 Identities = 59/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQK------STWKKKVKSLPN 478 R++++R K+ + R + Q+K+ K E I+E+ EK K KKK + Sbjct: 570 REERLR-KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 628 Query: 479 ILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKL-------RLLEQQELRE 531 + R K E + ++ EE R L+ K E+ +++L RL EQ+E Sbjct: 629 EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 688 Query: 532 KEEE-EEPEGKPSDAESSESSDDEKAWVE-EVRKQRRLLQQEEKVKRQERLKEDQQTVLK 589 +E+E E E + + E + E+ E E R+++ LQ E +++ +E+ Q+ L+ Sbjct: 689 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 748 Query: 590 PQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLT 644 + E K EE + + +++ K E +A N T+ V S Q+T Sbjct: 749 RELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMT 803 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 57.0 bits (136), Expect = 6e-08 Identities = 50/261 (19%), Positives = 113/261 (43%), Gaps = 14/261 (5%) Query: 430 RQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKV----KSLPNILTDDRF 485 +++ E+R +R ++++ V K + EE +K +K+ K + +++ Sbjct: 149 KEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQV 208 Query: 486 KVMFENPDFQVDEESEEFRLLNPLVS----KISEKRKKKLRLLEQQELREKEEEEEPEGK 541 +VM E + EE+ L N +S K E+R++ + E E+E++E E + Sbjct: 209 EVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAE 268 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEF 601 + E+ E + +++ +R ++ EEK QER + + + + + E +A EE Sbjct: 269 RARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEER 328 Query: 602 RSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEK 661 + K+ + E+R +I+ + + + ++ +R + +++E K Sbjct: 329 QRIKEEE------KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAK 382 Query: 662 LHRQERKRLRRSAGHLKSRHK 682 + Q+R + H K Sbjct: 383 VEEQKRNKQLEEKKHAMQETK 403 Score = 50.4 bits (119), Expect = 5e-06 Identities = 55/265 (20%), Positives = 121/265 (45%), Gaps = 24/265 (9%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILT 481 EE R + RQ+I+E + + ++ + +E K+ EE+++ K +KK + Sbjct: 348 EEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKV--EEQKRNKQLEEKKHAMQETKIK 405 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541 ++ + E + +++++E +L ++ K E++ K+ Q REK +E++P K Sbjct: 406 GEKVEQKIEGK-WVNEKKAQEDKLQTAVLKKQGEEKGTKV-----QAKREKLQEDKPTFK 459 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQE------RLKEDQQTVLKP---QF 592 + + + D++ EEV+ + +VK Q +LK + T +P Sbjct: 460 KEEIKDEKIKKDKEP-KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRAS 518 Query: 593 YEIKAGEEFRSFKDSATKQKLMNKTLE------DRLKIEAKNGTLSVSDTTVGSKQLTFT 646 + K E + ++L + E ++LK + + L + + ++ Sbjct: 519 VDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 578 Query: 647 LKRSEQQKKQQEAEKLHRQERKRLR 671 L+ EQ++KQ+EA++ R+E ++ R Sbjct: 579 LEEEEQRRKQEEADRKLREEEEKRR 603 Score = 44.3 bits (103), Expect = 4e-04 Identities = 64/300 (21%), Positives = 125/300 (41%), Gaps = 74/300 (24%) Query: 423 EYRKDKIRQKIEETR--AQRVQLKKLPKVNKELA-----------LKLIEEEEEKQKSTW 469 E R++ RQK EE R A+R+ ++ +E A L+ +EEE + T Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64 Query: 470 KKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQEL 529 + +V + N + D+ K N + D+E+ L ++ E+R+K+L QE Sbjct: 65 QVEVNA-QNSVPDEEAKTTTTNTQVEGDDEAAFLERL----ARREERRQKRL-----QEA 114 Query: 530 REKEEEEEP-------------------EGKPSDAESSESSDDEKAWVEEVRKQRRLLQQ 570 E+++E +P E + ++ E S E+ +EE + Q+ Sbjct: 115 LERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 174 Query: 571 -----------EEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLE 619 E+K K +E ++ ++ + E+ E+ ++ E Sbjct: 175 NDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEK-------------TTESQE 221 Query: 620 DRLKIEAKNGTLS------VSDTTVGSKQLTFTLKRSEQQKKQQEAE--KLHRQERKRLR 671 + + + KNG +S + GS +++ K E+ K++ EAE +L +ER+R++ Sbjct: 222 ETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIK 281 Score = 42.4 bits (98), Expect = 0.001 Identities = 49/252 (19%), Positives = 113/252 (44%), Gaps = 39/252 (15%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIE-EEEEKQKSTWKKKVKSLPNIL 480 EE ++++ R++ + + ++++ K E +E EE E+ K+ KK+ Sbjct: 236 EEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKI------- 288 Query: 481 TDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEG 540 D+R ++ E+EE K + + +++ E++ +RE+E+ E Sbjct: 289 ADERARI-----------EAEE---------KAAAQERERREAEERERMREEEKRAAEER 328 Query: 541 KPSDAESSESSDDEKAWVEEVRK---QRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKA 597 + E ++++ + EE ++ +R+ +++EEK +ER + + K + E K Sbjct: 329 QRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKR 388 Query: 598 GEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQ---K 654 ++ K + + K+ + +E +++ + N + D K T LK+ ++ K Sbjct: 389 NKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQED-----KLQTAVLKKQGEEKGTK 443 Query: 655 KQQEAEKLHRQE 666 Q + EKL + Sbjct: 444 VQAKREKLQEDK 455 Score = 41.2 bits (95), Expect = 0.003 Identities = 61/298 (20%), Positives = 117/298 (39%), Gaps = 38/298 (12%) Query: 422 EEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEE--EEEKQKSTWKKKVKSLPNI 479 EE +++ R+ +E Q+ + + L +V ++ + +EE + +T +V+ Sbjct: 35 EEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEA 94 Query: 480 LTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKIS------------------EKRKKKL 521 +R E ++ E E + +P ++ S EK +K Sbjct: 95 AFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSE 154 Query: 522 RLLEQQELREKEEEEEPEGKPS--DAESSESSDDEKAWVEEVRKQRRLLQQEE-KVKRQE 578 E+ E+ E E + K DAE ++ D EK EE + +R + + + +V +E Sbjct: 155 SRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEE 214 Query: 579 RLKEDQQTVLKPQFY-------EIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTL 631 + E Q+ + E K EE D + + M + ED+ + EA+ L Sbjct: 215 KTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEE--EDKERAEAERARL 272 Query: 632 SVSDT----TVGSKQLTFTLKRSEQQKKQ--QEAEKLHRQERKRLRRSAGHLKSRHKR 683 + K++ R E ++K QE E+ +ER+R+R +R Sbjct: 273 EAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQR 330 Score = 37.4 bits (85), Expect = 0.047 Identities = 37/173 (21%), Positives = 78/173 (45%), Gaps = 29/173 (16%) Query: 497 DEESEEFRLLNPL-------VSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSE 549 + ESEEF L + ++ +KR+++ ++LE++E R K+EE A+ Sbjct: 545 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE---------ADRKL 595 Query: 550 SSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLK---PQFYEIKAGEEFRSFKD 606 ++EK ++E ++RR E++ K E D + K P+ +K E Sbjct: 596 REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEE------- 648 Query: 607 SATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA 659 + + +NK+++ +++ + VS +Q T ++ ++ K + A Sbjct: 649 ---RAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPA 698 Score = 32.3 bits (72), Expect = 1.5 Identities = 35/184 (19%), Positives = 83/184 (45%), Gaps = 31/184 (16%) Query: 516 KRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVK 575 +R+++LR +++E+R + E + DDE+ E R++RR +QE + Sbjct: 5 ERRRELRRQKREEMRLEAER---------IAYQRNDDDEE---EAARERRRRARQERLRQ 52 Query: 576 RQERLK----------------EDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLE 619 +QE D++ +++ +E + A +++ K L+ Sbjct: 53 KQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQ 112 Query: 620 DRLKIEAK-NGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLK 678 + L+ + + + T++ + ++ S+++ +E +K++++E RQER + + K Sbjct: 113 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSES--RQERYEIEETETVTK 170 Query: 679 SRHK 682 S K Sbjct: 171 SYQK 174 Score = 32.3 bits (72), Expect = 1.5 Identities = 35/150 (23%), Positives = 72/150 (48%), Gaps = 6/150 (4%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLP-NILTDD 483 ++++ R+ +EE +R Q + K+ +E + ++EE E++++ +K + +P + L+DD Sbjct: 571 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDD 630 Query: 484 R--FKVMFENPDFQVDEESEEFRLLNPLVSKIS-EKRKKKLRLLEQQELREKEEEEEPEG 540 + FK EE EF LN V K S K + ++ + + R ++ EG Sbjct: 631 KKPFKCFTPKGSSLKIEERAEF--LNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEG 688 Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQ 570 S + ++ D E VR + + ++ Sbjct: 689 TKSAKPTKPAASDLPVPAEGVRNIKSMWEK 718 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 56.6 bits (135), Expect = 7e-08 Identities = 59/235 (25%), Positives = 106/235 (45%), Gaps = 16/235 (6%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQK------STWKKKVKSLPN 478 R++++R K+ + R + Q+K+ K E I+E+ EK K KKK + Sbjct: 574 REERLR-KVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKM 632 Query: 479 ILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKL-------RLLEQQELRE 531 + R K E + ++ EE R L+ K E+ +++L RL EQ+E Sbjct: 633 EEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQER 692 Query: 532 KEEE-EEPEGKPSDAESSESSDDEKAWVE-EVRKQRRLLQQEEKVKRQERLKEDQQTVLK 589 +E+E E E + + E + E+ E E R+++ LQ E +++ +E+ Q+ L+ Sbjct: 693 REQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ 752 Query: 590 PQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLT 644 + E K EE + + +++ K E +A N T+ V S Q+T Sbjct: 753 RELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMT 807 Score = 55.8 bits (133), Expect = 1e-07 Identities = 56/259 (21%), Positives = 113/259 (43%), Gaps = 51/259 (19%) Query: 430 RQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMF 489 RQK+EE + +R++ KL + + + E E+ K KK++ Sbjct: 556 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQI---------------- 599 Query: 490 ENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSE 549 E Q+DE++E+ + +++ K+K + +E+ E R K+E Sbjct: 600 EQKFAQIDEKTEKAK--EERLAEEKAKKKAAAKKMEEVEARRKQE--------------- 642 Query: 550 SSDDEKAWVEEVRKQRRLLQQEEKVKRQERL---KEDQQTVLKPQFYEIKAGEEFRSFKD 606 EE R+ R L Q+EE+ + QE L KE++Q L+ KA E R + Sbjct: 643 ---------EEARRLRWLQQEEEERRHQELLQKKKEEEQERLR------KAAEAKRLAEQ 687 Query: 607 SATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQE 666 +++ + ++R + E + + + ++ +R + +++ QE EK R + Sbjct: 688 REQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 747 Query: 667 RKRLRRSAGHLKSRHKRGR 685 +++L+R K + ++ R Sbjct: 748 KEQLQRELEEKKKKEEQQR 766 >gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo sapiens] Length = 551 Score = 55.8 bits (133), Expect = 1e-07 Identities = 61/259 (23%), Positives = 119/259 (45%), Gaps = 44/259 (16%) Query: 426 KDKIRQKIEETRAQRVQLKKLPKVNKELALKLIE-------EEEEKQKSTWKKKVKSLPN 478 + KI ++ E +L L +V KE A L++ E+EE+ K K + + + Sbjct: 145 RKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIILNAKCH 204 Query: 479 ILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEP 538 + D + + E Q + ++EE RL ++ E ++K + Q+EL K EE Sbjct: 205 AIRDAQ---ILEKQQIQKELDTEEKRL-----DQMMEVERQK-SIQRQEELERKRREERI 255 Query: 539 EGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERL-KEDQQTVLKPQFYEIKA 597 G+ E E + +E++ + E R+Q ++E+ ++ E+L +ED + + + Q ++K Sbjct: 256 RGRRQIVEQMEKNQEERSLLAEQREQ----EKEQMLEYMEQLQEEDLKDMERRQQQKLKM 311 Query: 598 GEEFRSFKDSATKQK---LMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQK 654 E + D KQK L + L D++ +E FT K+ ++ Sbjct: 312 QAEIKRINDENQKQKAELLAQEKLADQMVME-------------------FTKKKMAREA 352 Query: 655 K-QQEAEKLHRQERKRLRR 672 + + E E++ R++ K + R Sbjct: 353 EFEAEQERIRREKEKEIAR 371 Score = 42.4 bits (98), Expect = 0.001 Identities = 43/250 (17%), Positives = 107/250 (42%), Gaps = 28/250 (11%) Query: 431 QKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFE 490 ++++E + ++ ++ K+ + +K I +E +KQK+ + K ++ + K M Sbjct: 291 EQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAR 350 Query: 491 NPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSES 550 +F+ ++E +R+K+ + + ++EK ++ + E A+ ++ Sbjct: 351 EAEFEAEQERI--------------RREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQE 396 Query: 551 SDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKD--SA 608 D + W + ++ R + E R+ RL +Q K ++ + F+ A Sbjct: 397 VAD-REWRRKEKENARKKMETEAELRKSRL---EQVAFKEHALAVQVQRDRDEFERILRA 452 Query: 609 TKQKLMNKTLEDRLKI--------EAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAE 660 ++++ + LE+ K E + V ++ TF R +++ Q+ E Sbjct: 453 QREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRE 512 Query: 661 KLHRQERKRL 670 ++ +RK+L Sbjct: 513 RIDEIKRKKL 522 Score = 32.3 bits (72), Expect = 1.5 Identities = 41/191 (21%), Positives = 85/191 (44%), Gaps = 46/191 (24%) Query: 515 EKRKKKLRLLEQQELREKEEEEEPEGKPS-DAESSESS---DDEKAW--------VEEVR 562 E+ K +L ++EL +++ + E + + DA + E W +EEV Sbjct: 110 ERIKWASHVLTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVA 169 Query: 563 KQR--RLLQQEEKVK--RQERLKEDQQTVLKPQFYEIKAG---EEFRSFKDSATKQKLMN 615 K+R LLQ+ K++ ++E LK+ + +L + + I+ E+ + K+ T++K ++ Sbjct: 170 KERAQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLD 229 Query: 616 KTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAG 675 + +E ++R + ++Q+E E+ R+ER R RR Sbjct: 230 QMME---------------------------VERQKSIQRQEELERKRREERIRGRRQIV 262 Query: 676 HLKSRHKRGRS 686 +++ RS Sbjct: 263 EQMEKNQEERS 273 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 55.5 bits (132), Expect = 2e-07 Identities = 54/261 (20%), Positives = 122/261 (46%), Gaps = 32/261 (12%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEE--KQKSTWKKKVKSLPNILTD 482 ++ ++R++ + R Q Q+++ E ++ E+EE+ +Q+ +K+ + + + Sbjct: 169 QEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE--QE 226 Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKP 542 ++ + E Q+ E+ E+ + V K E+ +K+ + +QE + +E+EE+ + Sbjct: 227 EQMRKQEE----QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282 Query: 543 SDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQE---RLKEDQQTVLKPQFYEIKAGE 599 E E + +++ + E +Q R +QEE+++ QE R +E+Q + Q +E K E Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMR--EQEEQMREQEEQMREQEEQMGKQEEQMWEQK--E 338 Query: 600 EFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEA 659 + K+ KQ+ E++++ KQ K+ EQ +KQ+E Sbjct: 339 QMWEQKEQMWKQEEQMGEQEEQMQ-----------------KQEEQVRKQEEQMRKQEEQ 381 Query: 660 EKLHRQERKRLRRSAGHLKSR 680 + ++ ++ G K + Sbjct: 382 MRKQEEQMRKQEEQMGEQKEQ 402 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/180 (21%), Positives = 95/180 (52%), Gaps = 7/180 (3%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEE--KQKSTWKKKVKSLPNILTD 482 ++++++++ E+ + Q Q++K + +E ++ E+EE+ KQK +++ ++ Sbjct: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298 Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKR-KKKLRLLEQQELREKEEEEEPEGK 541 + + Q+ E+ E+ R + K E+ ++K ++ EQ+E K+EE+ E Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE-- 356 Query: 542 PSDAESSESSDDEKAWVEEVRKQR-RLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEE 600 + + + + + E++RKQ ++ +QEE++++QE +Q+ + Q +++ EE Sbjct: 357 -QEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEE 415 Score = 45.4 bits (106), Expect = 2e-04 Identities = 50/257 (19%), Positives = 124/257 (48%), Gaps = 19/257 (7%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEE-----EEKQKSTWKKKVKSLPNI 479 ++ ++R++ + R Q Q+++ +E ++ E+E +E Q + +V+ Sbjct: 71 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 130 Query: 480 LTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEE---E 536 + + +V + QV E+ + R V + + +++ + +QE + +E+E Sbjct: 131 VREQEGQV--REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188 Query: 537 EPEGKPSDAESSESSDDEKAWVEEVRKQRR---LLQQEEKV-KRQERLKEDQQTVLKPQF 592 E EG+ + E +E+ +E + Q++ + +QEE++ K++E++ E ++ V K + Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE 248 Query: 593 YEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQ 652 K E+ R ++ +Q+ + E+++ ++ K T T +Q ++ E+ Sbjct: 249 QVQKQEEQMRKQEEQMREQEEQMREQEEQM-LKQKEQTEQEEQTGEQEEQ----MREQEE 303 Query: 653 QKKQQEAEKLHRQERKR 669 Q ++QE + ++E+ R Sbjct: 304 QMREQEEQMREQEEQMR 320 Score = 35.8 bits (81), Expect = 0.14 Identities = 32/164 (19%), Positives = 84/164 (51%), Gaps = 32/164 (19%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE---EKQKSTWKKKVKSLPNILT 481 +++++R++ E+ R Q Q+++ + +E ++ ++EE E+++ W++K + Sbjct: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQ------- 346 Query: 482 DDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGK 541 M++ + Q+ E+ E+ +K+++++R +Q+E K+EE+ + + Sbjct: 347 ------MWKQEE-QMGEQEEQM-----------QKQEEQVR--KQEEQMRKQEEQMRKQE 386 Query: 542 PSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQ 585 + E ++K + E ++Q R +QEE++ Q+ Q+ Sbjct: 387 EQMRKQEEQMGEQKEQMGEQKEQMR--EQEEQMGEQKEQMRKQE 428 Score = 33.5 bits (75), Expect = 0.67 Identities = 32/163 (19%), Positives = 75/163 (46%), Gaps = 7/163 (4%) Query: 524 LEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKED 583 + +EL+EK E + E + + E SE K ++ + L QE +V+ QE + Sbjct: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVRE 63 Query: 584 QQTVLKPQFYEIKAGE-EFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQ 642 Q+ ++ Q +++ E + R + +Q+ + E ++ + G + + V ++ Sbjct: 64 QEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQV--RE 119 Query: 643 LTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 ++ E Q ++QE + R++ ++R G ++ + + R Sbjct: 120 QEGQVREQEGQVREQEGQV--REQEGQVREQEGQVREQEGQVR 160 >gi|115648142 centrosomal protein 164kDa [Homo sapiens] Length = 1460 Score = 55.5 bits (132), Expect = 2e-07 Identities = 59/277 (21%), Positives = 135/277 (48%), Gaps = 24/277 (8%) Query: 431 QKIEETRAQRVQLKKLPKVNKEL-ALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMF 489 Q+ E ++V + P V+ E+ + + + E+ ++ K +++ +L D+ ++ Sbjct: 553 QEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLE 612 Query: 490 ENPDFQV--------DEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEP-EG 540 + +EE E RL +S R++ + +E++E R +EEE + Sbjct: 613 SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW 672 Query: 541 KPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQER--LKEDQQTVLKPQFYEIKAG 598 + +SS +D+++ E+ ++L ++ E ++ ER L++ + +L+ EI+A Sbjct: 673 LRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEAS 732 Query: 599 EEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSV-SDTTVGSKQLTFTLKR------SE 651 E+ +A K+K + + L ++L+ E K ++ + + ++L +L+ S Sbjct: 733 EKSEQAALNAAKEKALQQ-LREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSS 791 Query: 652 QQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGRSFH 688 QKK QEA+ ++E +L++ G ++ R + +S+H Sbjct: 792 LQKKIQEAQ---QKEEAQLQKCLGQVEHRVHQ-KSYH 824 Score = 39.7 bits (91), Expect = 0.009 Identities = 59/298 (19%), Positives = 125/298 (41%), Gaps = 47/298 (15%) Query: 422 EEYRKDKIRQKI---EETRAQRVQLKKLPKVN--KELALKLIEEEE------EKQKSTWK 470 ++ + ++R+K+ EE R+ +K ++ +E K IEEEE E Q+ +W Sbjct: 614 KQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWL 673 Query: 471 KKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQ-EL 529 + +D+ + E ++ EE E + + + +K ++ L L+++ E Sbjct: 674 RAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAER--ASLEQKNRQMLEQLKEEIEA 731 Query: 530 REKEEE---------------EEPEGKPSDA----ESSESSDDEKAWVEEVRKQRRLLQQ 570 EK E+ E+ EG+ +A E S++ E+ K R ++ Sbjct: 732 SEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSS 791 Query: 571 EEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGT 630 +K ++ + KE+ Q L+ +++ +S+ + + +L + E R ++E ++ Sbjct: 792 LQKKIQEAQQKEEAQ--LQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEH-- 847 Query: 631 LSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGRSFH 688 ++ +K QQ + E+ +ERK+ GHL +R + H Sbjct: 848 ----------ERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAH 895 Score = 31.2 bits (69), Expect = 3.3 Identities = 53/253 (20%), Positives = 115/253 (45%), Gaps = 50/253 (19%) Query: 420 AYEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNI 479 A E+Y ++ +Q+ E +L++L + + E L+ + +E+ K+ +++ + Sbjct: 865 AREQYEAEERKQRAELLGHLTGELERLQRAH-ERELETVRQEQHKRLEDLRRRHREQERK 923 Query: 480 LTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLE-QQELREKEEEEEP 538 L D ++D E+ ++ K +L LLE Q+E +E+++ Sbjct: 924 LQD-----------LELDLETR------------AKDVKARLALLEVQEETARREKQQLL 960 Query: 539 EGKPSDAESSESSDDEKAWVEEVRKQR-RLLQQEEKVK------RQERLK-EDQQTVLKP 590 + + A SE + +EE +K+ LLQ ++++ + +LK E Q +L+ Sbjct: 961 DVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDLLQA 1020 Query: 591 QFYEIKAGEEFRSFKDSATKQK--LMNKTLEDR---------LKIEAKNGTLSVSDTTVG 639 Q +++ + F S + A K++ L T+E+ L IE +L + T Sbjct: 1021 QSQQLQ--KHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQT--- 1075 Query: 640 SKQLTFTLKRSEQ 652 K+++ +L +S++ Sbjct: 1076 -KEVSSSLSQSKE 1087 Score = 30.4 bits (67), Expect = 5.7 Identities = 33/145 (22%), Positives = 57/145 (39%), Gaps = 3/145 (2%) Query: 531 EKEEEEEPEGKPSDAESSESSDDEKAWVE-EVRKQRRLLQQEEKVKRQERLKEDQQTVLK 589 E+E + PEG+P E+ E +D A + ++ QR + + + Q L Sbjct: 491 EEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELG 550 Query: 590 PQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGS--KQLTFTL 647 P E + EE + + + T + L + V +Q L Sbjct: 551 PGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHL 610 Query: 648 KRSEQQKKQQEAEKLHRQERKRLRR 672 S+Q+K QQ EKL ++E + + R Sbjct: 611 LESKQEKMQQLREKLCQEEEEEILR 635 >gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] Length = 238 Score = 55.1 bits (131), Expect = 2e-07 Identities = 51/203 (25%), Positives = 101/203 (49%), Gaps = 24/203 (11%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEE----------EKQKSTWKKKVK 474 R+ K+R++ E R Q ++++ + +E K+ E+EE E+++ W+++ K Sbjct: 10 REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEK 69 Query: 475 SLPNILTDDRFKVMFENPDFQVDEESEEFR--LLNPLVSKISEKRKKKLRLLEQQELREK 532 ++ + M+E D ++ E+ E R + V K+ EK+K + +++QE + + Sbjct: 70 MWEQQRLPEQKEKMWEQ-DERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128 Query: 533 EEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQF 592 E+EE + E +EK W +E ++ +QEEK++ QE + Q+ K + Sbjct: 129 EQEE----MMWEQEEKMQEQEEKMWEQE----EKMREQEEKMREQEEKMQGQEE--KMRD 178 Query: 593 YEIKAGEEFR-SFKDSATKQKLM 614 E GE S +D+ T Q++M Sbjct: 179 VEPAGGEAGEGSPQDNPTAQEIM 201 Score = 51.2 bits (121), Expect = 3e-06 Identities = 36/176 (20%), Positives = 83/176 (47%), Gaps = 6/176 (3%) Query: 516 KRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQ---RRLLQQEE 572 + ++++R E++ E+E E E K + E +EK W +E + Q ++ +QEE Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 Query: 573 KVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLS 632 K+ QE +QQ + + + + E R ++ +QK+ + + R K + + + Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 Query: 633 VSDTTVGSKQLTF---TLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGR 685 + + ++ K EQ++K E E+ R++ +++R ++ + ++ R Sbjct: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 55.1 bits (131), Expect = 2e-07 Identities = 49/181 (27%), Positives = 83/181 (45%), Gaps = 11/181 (6%) Query: 512 KISEKRKKKLRLLEQQELREKEEEEEPE-GKPSDAESSESSDDEKAWVEEVRKQRRLLQQ 570 KI EK + K + E++ REKE E+E E GK D + D EK ++ ++R + Sbjct: 383 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 442 Query: 571 EEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGT 630 +++ K +E+ ++ ++ K + EI E+ + K S T + N + R + Sbjct: 443 KDRDKEKEKEQDKEKEREKDRSKEI--DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 500 Query: 631 LSVSDT-------TVGSKQLTFTLKRSEQQK-KQQEAEKLHRQERKRLRRSAGHLKSRHK 682 S S + T+ K RS +K K++E E+ H ER+ RS KS + Sbjct: 501 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 560 Query: 683 R 683 R Sbjct: 561 R 561 Score = 33.1 bits (74), Expect = 0.88 Identities = 35/166 (21%), Positives = 60/166 (36%), Gaps = 21/166 (12%) Query: 511 SKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQR----- 565 SK K R Q + D S+S +++ E RK R Sbjct: 314 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 373 Query: 566 --RLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLK 623 + EK+K +ER+KE K E+ R + K+K K +DR K Sbjct: 374 RDKRKDTREKIKEKERVKE-------------KDREKEREREKEREKEKERGKN-KDRDK 419 Query: 624 IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKR 669 K+ ++ R ++++K+Q+ EK ++R + Sbjct: 420 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 465 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 55.1 bits (131), Expect = 2e-07 Identities = 49/181 (27%), Positives = 83/181 (45%), Gaps = 11/181 (6%) Query: 512 KISEKRKKKLRLLEQQELREKEEEEEPE-GKPSDAESSESSDDEKAWVEEVRKQRRLLQQ 570 KI EK + K + E++ REKE E+E E GK D + D EK ++ ++R + Sbjct: 267 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 326 Query: 571 EEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGT 630 +++ K +E+ ++ ++ K + EI E+ + K S T + N + R + Sbjct: 327 KDRDKEKEKEQDKEKEREKDRSKEI--DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 384 Query: 631 LSVSDT-------TVGSKQLTFTLKRSEQQK-KQQEAEKLHRQERKRLRRSAGHLKSRHK 682 S S + T+ K RS +K K++E E+ H ER+ RS KS + Sbjct: 385 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 444 Query: 683 R 683 R Sbjct: 445 R 445 Score = 33.1 bits (74), Expect = 0.88 Identities = 35/166 (21%), Positives = 60/166 (36%), Gaps = 21/166 (12%) Query: 511 SKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQR----- 565 SK K R Q + D S+S +++ E RK R Sbjct: 198 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 257 Query: 566 --RLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLK 623 + EK+K +ER+KE K E+ R + K+K K +DR K Sbjct: 258 RDKRKDTREKIKEKERVKE-------------KDREKEREREKEREKEKERGKN-KDRDK 303 Query: 624 IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKR 669 K+ ++ R ++++K+Q+ EK ++R + Sbjct: 304 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 349 >gi|94721321 coiled-coil domain containing 11 [Homo sapiens] Length = 514 Score = 54.3 bits (129), Expect = 4e-07 Identities = 62/252 (24%), Positives = 113/252 (44%), Gaps = 22/252 (8%) Query: 433 IEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENP 492 IEE R + +L L + ++L +E E++K ++K K L +R + E Sbjct: 94 IEERRNKLRELLALEENEYFTEMQLKKETIEEKKDRMREKTKLLKEKNEKERQDFVAEKL 153 Query: 493 DFQVDEESEEFR--LLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSES 550 D Q E EE R LL+ K+ E+RK ++ E+ R+K EE+ K + + Sbjct: 154 DQQFRERCEELRVELLSIHQKKVCEERKAQIAFNEELS-RQKLVEEQMFSKLWEEDRLAK 212 Query: 551 SDDEKAWVEEVRKQRRLLQQEE----------KVKRQ--ERLKEDQQTVLKPQFYEIKAG 598 EK +E R+Q+ L++ K +RQ + LKE++ +++ +IK Sbjct: 213 ---EKREAQEARRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLVESNNAQIKHE 269 Query: 599 EEFRSFKDSATKQK---LMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKK 655 E K KQ+ ++ K L++R++ + D + Q + E KK Sbjct: 270 NEQDMLKKQKAKQETRTILQKALQERIE-HIQQEYRDEQDLNMKLVQRALQDLQEEADKK 328 Query: 656 QQEAEKLHRQER 667 +Q+ E + R+++ Sbjct: 329 KQKREDMIREQK 340 Score = 33.1 bits (74), Expect = 0.88 Identities = 62/278 (22%), Positives = 112/278 (40%), Gaps = 66/278 (23%) Query: 429 IRQKIEETRAQRVQLKKLPKVNKELALKLIE------EEEEKQKSTWKKKVKSLPNILTD 482 + +I +AQR + L KE +L+E + E +Q K+K K + Sbjct: 234 LNAQITSIKAQRQATQLL----KEEEARLVESNNAQIKHENEQDMLKKQKAKQETRTILQ 289 Query: 483 DRFKVMFENPDFQVDEESE-----EFRLLNPLVSKISEKRKKKLRLLEQQE-----LREK 532 + E+ + +E + R L L + +K++K+ ++ +Q+ L ++ Sbjct: 290 KALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQR 349 Query: 533 EEEEEPEGKPSD-------AESSESSDDE--------KAWVEEVRKQRRLLQQEEKVKRQ 577 EEE+ + K D A+ D E + V+EV R+ LQ +EK++R+ Sbjct: 350 REEEKAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVMCTRK-LQVQEKLQRE 408 Query: 578 ERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTT 637 + +E++ A +QK +N++L++ E +N Sbjct: 409 AKEQEER-----------------------AMEQKHINESLKELNCEEKENFARRQRLAQ 445 Query: 638 VGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAG 675 KQL + Q++ QEAEK E KR AG Sbjct: 446 EYRKQLQMQI---AYQQQSQEAEK----EEKRREFEAG 476 >gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1 [Homo sapiens] Length = 621 Score = 53.9 bits (128), Expect = 5e-07 Identities = 55/236 (23%), Positives = 108/236 (45%), Gaps = 41/236 (17%) Query: 460 EEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVS-------- 511 +EEEK+K+ + D+R + +N + + EE + LV Sbjct: 231 DEEEKEKAECR-----------DERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPR 279 Query: 512 ----KISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRL 567 K EK KK+ + E + KE+E + + + ++ E++ + +++ EEVR+Q L Sbjct: 280 IKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEE--EEVRQQALL 337 Query: 568 LQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLE---DRLK- 623 ++E+ ++++ KE Q+ + + + F D+ ++ M + +E DRL+ Sbjct: 338 AKKEKDIQKKAIKKERQKL--------RNSCKTWNHFSDNEAERVKMMEEVEKLCDRLEL 389 Query: 624 --IEAKNGTLSVSDTTVGSKQLTFTLKRSEQQ--KKQQEAEKLHRQERKRLRRSAG 675 ++ N TL+ VG L ++ +Q K+++EAE RQ K +S G Sbjct: 390 ASLQCLNETLTSCTKEVGKAALEKQIEEINEQIRKEKEEAEARMRQASKNTEKSTG 445 >gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] Length = 523 Score = 53.5 bits (127), Expect = 6e-07 Identities = 46/186 (24%), Positives = 96/186 (51%), Gaps = 13/186 (6%) Query: 495 QVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEE---EPEGKPSDAESSESS 551 Q+ E E ++L+ L + E+ +++ L +QE R +E+EE E E + + E Sbjct: 179 QLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLRE 238 Query: 552 DDEKAWVEEVR---KQRRLLQQEEKV-KRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDS 607 +E+ +E R + RL +QEE++ +++ERL+E ++ + + + + E R ++ Sbjct: 239 QEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEER 298 Query: 608 ATKQKLMNKTLEDRL-----KIEAKNGTLSVSDTTVGSKQLTFTL-KRSEQQKKQQEAEK 661 +Q+ + E+RL ++ + L + G ++L + K EQ+++Q+E E+ Sbjct: 299 LCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQER 358 Query: 662 LHRQER 667 L +ER Sbjct: 359 LLERER 364 Score = 45.1 bits (105), Expect = 2e-04 Identities = 42/170 (24%), Positives = 80/170 (47%), Gaps = 13/170 (7%) Query: 430 RQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMF 489 R++ E R Q +L++ + +E +L E+EE ++ + + + ++R + Sbjct: 195 RRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHE 254 Query: 490 ENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQE-LREKEEE---------EEPE 539 E Q + E+ L ++ E+ + RL EQ+E LRE+EE E+ E Sbjct: 255 ERLCEQEERLCEQEERLREQEERLHEQEE---RLCEQEERLREQEERLCEQEERLREQEE 311 Query: 540 GKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLK 589 E ++ E++ Q RLL++ EK+ QER +E+Q+ +L+ Sbjct: 312 RLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLE 361 Score = 36.2 bits (82), Expect = 0.10 Identities = 54/230 (23%), Positives = 108/230 (46%), Gaps = 33/230 (14%) Query: 425 RKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEE--KQKSTWKKKVKSLPNILTD 482 +++++R++ E R Q +L + + +E +L E+EE +Q+ +++ + L + Sbjct: 225 QEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHE--QE 282 Query: 483 DRFKVMFENPDFQVDEESEEFRLLNPLVSKISEK----RKKKLRLLEQQEL-------RE 531 +R E Q + E+ L ++ E+ R+++ RL EQ++L E Sbjct: 283 ERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEE 342 Query: 532 KEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKV------KRQERLKEDQQ 585 E+ E E + + E + VEE+ +Q RL QQ+E++ + ERL+E ++ Sbjct: 343 VEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELER 402 Query: 586 TV------LKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNG 629 + L Q E ++G E + ++ +T Q LE ++K K+G Sbjct: 403 MLELGWEALYEQRAEPRSGFEELNNENKSTLQ------LEQQVKELKKSG 446 Score = 34.7 bits (78), Expect = 0.30 Identities = 37/159 (23%), Positives = 73/159 (45%), Gaps = 24/159 (15%) Query: 526 QQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQE-RLKEDQ 584 Q E +E E G+ AE +++ + R++ RL +QEE+++ QE RL+E + Sbjct: 163 QDETNHLRKELESVGRQLQAEVE---NNQMLSLLNRRQEERLREQEERLREQEERLREQE 219 Query: 585 QTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLT 644 + + + + + E R ++ +Q+ + E+RL + + Sbjct: 220 ERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEER---------------- 263 Query: 645 FTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKR 683 L E++ ++QE E+LH QE +RL L+ + +R Sbjct: 264 --LCEQEERLREQE-ERLHEQE-ERLCEQEERLREQEER 298 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.133 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,545,100 Number of Sequences: 37866 Number of extensions: 1226863 Number of successful extensions: 20195 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 298 Number of HSP's successfully gapped in prelim test: 1021 Number of HSP's that attempted gapping in prelim test: 9614 Number of HSP's gapped (non-prelim): 5695 length of query: 688 length of database: 18,247,518 effective HSP length: 109 effective length of query: 579 effective length of database: 14,120,124 effective search space: 8175551796 effective search space used: 8175551796 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.