Search of human proteins with 170932526

Search of human proteins with 170932526

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|170932526 nuclear receptor coactivator 7 isoform 2 [Homo
sapiens]
         (931 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|170932526 nuclear receptor coactivator 7 isoform 2 [Homo sapi...  1869   0.0  
gi|170932524 nuclear receptor coactivator 7 isoform 1 [Homo sapi...  1861   0.0  
gi|194306543 oxidation resistance 1 isoform 2 [Homo sapiens]          340   3e-93
gi|194306541 oxidation resistance 1 isoform 1 [Homo sapiens]          340   3e-93
gi|62909985 hypothetical protein LOC140711 [Homo sapiens]             191   2e-48
gi|205360930 hypothetical protein LOC57707 [Homo sapiens]              79   2e-14
gi|89886453 TBC1 domain family, member 24 [Homo sapiens]               69   2e-11
gi|221219020 NYD-SP11 protein [Homo sapiens]                           40   0.008
gi|34577118 dopey family member 1 [Homo sapiens]                       40   0.008
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    40   0.010
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H...    39   0.023
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    39   0.023
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]            38   0.038
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    38   0.038
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          38   0.038
gi|41281453 serine/threonine kinase 2 [Homo sapiens]                   38   0.038
gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sap...    37   0.086
gi|114326455 chromodomain helicase DNA binding protein 8 [Homo s...    37   0.086
gi|169646281 coiled-coil domain containing 14 [Homo sapiens]           37   0.11 
gi|45439327 periplakin [Homo sapiens]                                  37   0.11 
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]     36   0.15 
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]     36   0.15 
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     36   0.15 
gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]               36   0.15 
gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]                36   0.15 
gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo sa...    36   0.15 
gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo sap...    36   0.15 
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...    36   0.15 
gi|18921093 transient receptor potential cation channel, subfami...    36   0.19 
gi|7657544 sodium channel, voltage gated, type VIII, alpha [Homo...    36   0.19 

>gi|170932526 nuclear receptor coactivator 7 isoform 2 [Homo
           sapiens]
          Length = 931

 Score = 1869 bits (4842), Expect = 0.0
 Identities = 931/931 (100%), Positives = 931/931 (100%)

Query: 1   MDTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVE 60
           MDTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVE
Sbjct: 1   MDTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVE 60

Query: 61  EEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAGN 120
           EEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAGN
Sbjct: 61  EEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAGN 120

Query: 121 QDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSP 180
           QDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSP
Sbjct: 121 QDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSP 180

Query: 181 SSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVM 240
           SSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVM
Sbjct: 181 SSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVM 240

Query: 241 IVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSPGEWE 300
           IVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSPGEWE
Sbjct: 241 IVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSPGEWE 300

Query: 301 DLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTGHTPTKPSGSSVSEKL 360
           DLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTGHTPTKPSGSSVSEKL
Sbjct: 301 DLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTGHTPTKPSGSSVSEKL 360

Query: 361 KKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMH 420
           KKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMH
Sbjct: 361 KKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMH 420

Query: 421 KKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQD 480
           KKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQD
Sbjct: 421 KKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQD 480

Query: 481 IMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENLQKTELSDGKSI 540
           IMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENLQKTELSDGKSI
Sbjct: 481 IMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENLQKTELSDGKSI 540

Query: 541 EPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEANVIKEALDSSLE 600
           EPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEANVIKEALDSSLE
Sbjct: 541 EPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEANVIKEALDSSLE 600

Query: 601 STLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSF 660
           STLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSF
Sbjct: 601 STLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSF 660

Query: 661 ATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEE 720
           ATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEE
Sbjct: 661 ATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEE 720

Query: 721 LNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQL 780
           LNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQL
Sbjct: 721 LNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQL 780

Query: 781 ARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPF 840
           ARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPF
Sbjct: 781 ARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPF 840

Query: 841 KFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYH 900
           KFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYH
Sbjct: 841 KFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYH 900

Query: 901 GRSNSCSTFNNDILSKKEDFIVQDLEVWAFD 931
           GRSNSCSTFNNDILSKKEDFIVQDLEVWAFD
Sbjct: 901 GRSNSCSTFNNDILSKKEDFIVQDLEVWAFD 931


>gi|170932524 nuclear receptor coactivator 7 isoform 1 [Homo
           sapiens]
          Length = 942

 Score = 1861 bits (4820), Expect = 0.0
 Identities = 931/942 (98%), Positives = 931/942 (98%), Gaps = 11/942 (1%)

Query: 1   MDTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVE 60
           MDTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVE
Sbjct: 1   MDTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVE 60

Query: 61  EEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAGN 120
           EEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAGN
Sbjct: 61  EEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAGN 120

Query: 121 QDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSP 180
           QDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSP
Sbjct: 121 QDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSP 180

Query: 181 SSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVM 240
           SSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVM
Sbjct: 181 SSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVM 240

Query: 241 IVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPS----- 295
           IVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPS     
Sbjct: 241 IVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQD 300

Query: 296 ------PGEWEDLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTGHTPT 349
                 PGEWEDLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTGHTPT
Sbjct: 301 LCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTGHTPT 360

Query: 350 KPSGSSVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLE 409
           KPSGSSVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLE
Sbjct: 361 KPSGSSVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLE 420

Query: 410 ELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKG 469
           ELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKG
Sbjct: 421 ELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKG 480

Query: 470 ALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENL 529
           ALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENL
Sbjct: 481 ALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENL 540

Query: 530 QKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEAN 589
           QKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEAN
Sbjct: 541 QKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEAN 600

Query: 590 VIKEALDSSLESTLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLC 649
           VIKEALDSSLESTLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLC
Sbjct: 601 VIKEALDSSLESTLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMFLC 660

Query: 650 IKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAK 709
           IKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAK
Sbjct: 661 IKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAK 720

Query: 710 EQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEEVLPVLRPHS 769
           EQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEEVLPVLRPHS
Sbjct: 721 EQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDEEVLPVLRPHS 780

Query: 770 ALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDN 829
           ALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDN
Sbjct: 781 ALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDN 840

Query: 830 QIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGR 889
           QIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGR
Sbjct: 841 QIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGR 900

Query: 890 FGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWAFD 931
           FGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWAFD
Sbjct: 901 FGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWAFD 942


>gi|194306543 oxidation resistance 1 isoform 2 [Homo sapiens]
          Length = 839

 Score =  340 bits (873), Expect = 3e-93
 Identities = 163/307 (53%), Positives = 210/307 (68%), Gaps = 5/307 (1%)

Query: 630 IEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERV 689
           IE     KE++      FLC++VGKPMRK+F +  +A +QQY +R K+ EYWFAVP+ER 
Sbjct: 533 IESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERT 592

Query: 690 DHLYTFFVQWSPDVYGKDA----KEQGFVVVEK-EELNMIDNFFSEPTTKSWEIITVEEA 744
           DHLY FF+QWSP++Y +D     +E GF+VV+K EE   I++  ++   + WEI T E+ 
Sbjct: 593 DHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDI 652

Query: 745 KRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGT 804
             ++      + E E   P L   S LL    IE+L + LP R  GYPW L Y T +HGT
Sbjct: 653 NSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGT 712

Query: 805 SLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVF 864
           SLKTLYR    LD+PVL+VIKD D Q+FGA A+ P K SD +YGTGETF++TF P F+VF
Sbjct: 713 SLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVF 772

Query: 865 KWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQD 924
           KW+G+N +FI GD+ SL  GGGGG F LWLD DLYHGRS+SC TF N  LSKKEDF +QD
Sbjct: 773 KWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQD 832

Query: 925 LEVWAFD 931
           +E+WAF+
Sbjct: 833 IEIWAFE 839



 Score =  237 bits (605), Expect = 3e-62
 Identities = 152/353 (43%), Positives = 199/353 (56%), Gaps = 33/353 (9%)

Query: 91  DDNQNKTHDKKE-KKMVVQKPHGTMEYTAGNQDTLNSIALKFNITPNKLVELNKLFTHTI 149
           D  Q KT DKK+ ++M  QKP GT+EYT  ++D+LNSIALKF+ TPN+LV+LNKLF+  +
Sbjct: 67  DTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAV 126

Query: 150 VPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKPIE----- 204
           V GQVL+VPD    SS     S SP + +SP+SS+AE+DK  + D+      P       
Sbjct: 127 VTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGI 186

Query: 205 ---RVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIEN 261
              RV+SSTSEE+E    KFLK+NC+Y T GKG V GV++VTPNNIMFDPHK+DPLV EN
Sbjct: 187 RPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQEN 246

Query: 262 GCEEYGLICPMEEVVSIALYNDISHMKIKDALPSPGEWEDLASEKDINPFSKFKSINKEK 321
           GCEEYG++CPMEEV+S A+Y +I   KIK++LP      D  S +D     K    N E+
Sbjct: 247 GCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPID---IDQLSGRDFCHSKKMTGSNTEE 303

Query: 322 -----RQQNGEKIMTSDSRPIVPLEKSTGHTPTKPSGSSVSEKLKKLD------SSRETS 370
                R    +   T+   P    E  +    T+   S + E+L   D      SS  +S
Sbjct: 304 IDSRIRDAGNDSASTA---PRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASS 360

Query: 371 HGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMHKKD 423
               TV +   E     S  EST     L       D E  +++ G   HK D
Sbjct: 361 ESVQTVNQAEVESLTVKS--ESTGTPGHLRS-----DTEHSTNEVGTLCHKTD 406


>gi|194306541 oxidation resistance 1 isoform 1 [Homo sapiens]
          Length = 846

 Score =  340 bits (873), Expect = 3e-93
 Identities = 163/307 (53%), Positives = 210/307 (68%), Gaps = 5/307 (1%)

Query: 630 IEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERV 689
           IE     KE++      FLC++VGKPMRK+F +  +A +QQY +R K+ EYWFAVP+ER 
Sbjct: 540 IESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERT 599

Query: 690 DHLYTFFVQWSPDVYGKDA----KEQGFVVVEK-EELNMIDNFFSEPTTKSWEIITVEEA 744
           DHLY FF+QWSP++Y +D     +E GF+VV+K EE   I++  ++   + WEI T E+ 
Sbjct: 600 DHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDI 659

Query: 745 KRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGT 804
             ++      + E E   P L   S LL    IE+L + LP R  GYPW L Y T +HGT
Sbjct: 660 NSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGT 719

Query: 805 SLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVF 864
           SLKTLYR    LD+PVL+VIKD D Q+FGA A+ P K SD +YGTGETF++TF P F+VF
Sbjct: 720 SLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVF 779

Query: 865 KWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQD 924
           KW+G+N +FI GD+ SL  GGGGG F LWLD DLYHGRS+SC TF N  LSKKEDF +QD
Sbjct: 780 KWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQD 839

Query: 925 LEVWAFD 931
           +E+WAF+
Sbjct: 840 IEIWAFE 846



 Score =  257 bits (656), Expect = 4e-68
 Identities = 162/378 (42%), Positives = 215/378 (56%), Gaps = 33/378 (8%)

Query: 66  DEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKE-KKMVVQKPHGTMEYTAGNQDTL 124
           +E+    + Q    RR+ELKR+Y+ID  Q KT DKK+ ++M  QKP GT+EYT  ++D+L
Sbjct: 49  EEQNNAANTQKHPSRRSELKRFYTIDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSL 108

Query: 125 NSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSD 184
           NSIALKF+ TPN+LV+LNKLF+  +V GQVL+VPD    SS     S SP + +SP+SS+
Sbjct: 109 NSIALKFDTTPNELVQLNKLFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSE 168

Query: 185 AEYDKLPDADLARKALKPIE--------RVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVV 236
           AE+DK  + D+      P          RV+SSTSEE+E    KFLK+NC+Y T GKG V
Sbjct: 169 AEFDKTTNPDVHPTEATPSSTFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTV 228

Query: 237 GGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSP 296
            GV++VTPNNIMFDPHK+DPLV ENGCEEYG++CPMEEV+S A+Y +I   KIK++LP  
Sbjct: 229 SGVLLVTPNNIMFDPHKNDPLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPID 288

Query: 297 GEWEDLASEKDINPFSKFKSINKEK-----RQQNGEKIMTSDSRPIVPLEKSTGHTPTKP 351
               D  S +D     K    N E+     R    +   T+   P    E  +    T+ 
Sbjct: 289 ---IDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTA---PRSTEESLSEDVFTES 342

Query: 352 SGSSVSEKLKKLD------SSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDF 405
             S + E+L   D      SS  +S    TV +   E     S  EST     L      
Sbjct: 343 ELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKS--ESTGTPGHLRS---- 396

Query: 406 VDLEELSSQTGGGMHKKD 423
            D E  +++ G   HK D
Sbjct: 397 -DTEHSTNEVGTLCHKTD 413


>gi|62909985 hypothetical protein LOC140711 [Homo sapiens]
          Length = 215

 Score =  191 bits (486), Expect = 2e-48
 Identities = 84/171 (49%), Positives = 117/171 (68%)

Query: 758 DEEVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLD 817
           ++  +P L   S +L    I QL+   P RV G+PW L + T   G SL++LYR+     
Sbjct: 42  EDPTVPQLTEASQVLSASEIRQLSFHFPPRVTGHPWSLVFCTSRDGFSLQSLYRRMEGCS 101

Query: 818 SPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGD 877
            PVLLV++D D QIFGA+++   + S  +YGTGETFL++FSP  KVFKW+G NS+F+ GD
Sbjct: 102 GPVLLVLRDQDGQIFGAFSSSAIRLSKGFYGTGETFLFSFSPQLKVFKWTGSNSFFVKGD 161

Query: 878 ISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVW 928
           + SL +G G GRFGLWLD DL+ G S+ C TFNN++L+++E F +Q+LE W
Sbjct: 162 LDSLMMGSGSGRFGLWLDGDLFRGGSSPCPTFNNEVLARQEQFCIQELEAW 212


>gi|205360930 hypothetical protein LOC57707 [Homo sapiens]
          Length = 456

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 50/173 (28%), Positives = 87/173 (50%), Gaps = 11/173 (6%)

Query: 766 RPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIK 825
           R   ++L+ + +  +  +LP R Q + W L +S+  HG S   L         P + V++
Sbjct: 240 RGFESILDVLSVMYINAQLP-REQRHRWCLLFSSELHGHSFSQLCGHITHR-GPCVAVLE 297

Query: 826 DMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFI---NGD---IS 879
           D D  +FG +A+  ++    + G    FL++  P   V+  +G N +++   +G     +
Sbjct: 298 DHDKHVFGGFASCSWEVKPQFQGDNRCFLFSICPSMAVYTHTGYNDHYMYLNHGQQTIPN 357

Query: 880 SLELGGGGGRFGLWLDADLYHGRSN---SCSTFNNDILSKKEDFIVQDLEVWA 929
            L +GG    FGLW+D D   G S    +C+T+N+  LS +E+F    +EVWA
Sbjct: 358 GLGMGGQHNYFGLWVDVDFGKGHSRAKPTCTTYNSPQLSAQENFQFDKMEVWA 410


>gi|89886453 TBC1 domain family, member 24 [Homo sapiens]
          Length = 553

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 52/189 (27%), Positives = 80/189 (42%), Gaps = 56/189 (29%)

Query: 795 LAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPF----KFSDH--YYG 848
           L +S+L+HG SL   Y +    + P LL+IK    ++ GAY +  +    KF     ++G
Sbjct: 362 LLFSSLQHGYSLARFYFQCEGHE-PTLLLIKTTQKEVCGAYLSTDWSERNKFGGKLGFFG 420

Query: 849 TGETFLYTFSPHFKVFKW------------------------------------------ 866
           TGE F++   P  + ++W                                          
Sbjct: 421 TGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLSPFLAAR 480

Query: 867 -----SGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFI 921
                S   S F+ G    L +GGGGG+  L++D DL  GR++ C TFNN  L   E+F+
Sbjct: 481 HFNLPSKTESMFMAGGSDCLIVGGGGGQ-ALYIDGDLNRGRTSHCDTFNNQPLC-SENFL 538

Query: 922 VQDLEVWAF 930
           +  +E W F
Sbjct: 539 IAAVEAWGF 547


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 47/215 (21%), Positives = 88/215 (40%), Gaps = 18/215 (8%)

Query: 315  KSINKEKRQQNGEKIMTSDSRPIVPLEKSTGHTPTKPSGSSVSEKL----KKLDSSRETS 370
            K  NK +R  N E+ MT +   +            +  G    E +    ++    +E  
Sbjct: 2145 KLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAK 2204

Query: 371  HGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVD----LEELSSQTGGGMHKKDTLK 426
             G     K S +  +  S      +E+F  E +  +D     E LSS+      +++  +
Sbjct: 2205 RGDKPKEKFSSQVDEVES------EEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258

Query: 427  ECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQDIMPEVD 486
            E    + EE +K E +     VE + +        +   E++   ++   EK++IM E +
Sbjct: 2259 EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFE-EKEEIMSEEE 2317

Query: 487  KQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKE 521
             +S S E   E + ++ E++D+ K I   L K K+
Sbjct: 2318 TESLSDEEEEEESCSLEEEVDREKEI---LKKEKQ 2349


>gi|34577118 dopey family member 1 [Homo sapiens]
          Length = 2465

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 48/237 (20%), Positives = 99/237 (41%), Gaps = 27/237 (11%)

Query: 272  MEEVVSIALYNDISHMKIKDA-LPSPGEWEDLASE-KDINPFSKFKSINKEKRQQNGEKI 329
            +++VV   +   +S ++++ A + S  E E +  +  DI+P  +   I  +  QQ+   +
Sbjct: 1149 VQQVVFDLICKVVSGLEVESASVTSQLEIEAMPPKCSDIDPDEETIKIEDDSIQQSQNAL 1208

Query: 330  MTSDSRPIVPLEKSTGHTPTKPSGSSVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSA 389
            ++++S   + +    GH     +G S +     +  +  T H S   +  +K    + S+
Sbjct: 1209 LSNESSQFLSVSAEGGHECVA-NGISRNSSSPCISGTTHTLHDSSVASIETKSRQRSHSS 1267

Query: 390  FESTAKENFLGEDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVE 449
             + + KE      +   + E +  ++G     K  +K     D +++K +  ++  ++V 
Sbjct: 1268 IQFSFKEKL---SEKVSEKETIVKESGKQPGAKPKVKLARKKDDDKKKSSNEKLKQTSVF 1324

Query: 450  MQVQSALAFLGTENDVELKGALDLE---TCEKQDIMPEVDKQSGSPESRVENTLNIH 503
                                 LDLE   +C + DI  E++   GSP SR     NIH
Sbjct: 1325 FS-----------------DGLDLENWYSCGEGDIS-EIESDMGSPGSRKSPNFNIH 1363


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 59/286 (20%), Positives = 106/286 (37%), Gaps = 40/286 (13%)

Query: 381 KEPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAE 440
           +EP  +    +   K+    EDD   +LEELS +  G   K D  +E +++ P E  + E
Sbjct: 35  QEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQG--IKAD--RETVAVKPTENNEEE 90

Query: 441 SQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQDIMPEVDKQSGSPESRVENTL 500
               +   + Q     +F    +D + +   D ++  K+   P+V+  SGS +    N L
Sbjct: 91  FTSKDKKKKGQKGKKQSF----DDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKL 146

Query: 501 ----------------NIHEDLDKVKLIEYYLTKNKEGPQVSENLQKTELSDGKSIEPGG 544
                              ED D  K I+     N  G    E+ +  +   G+      
Sbjct: 147 PKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQK----- 201

Query: 545 IDITLSSSLSQAGDPITEGNKEPDKTW------VKKGEPLPVKLNSSTEANVIKEALDSS 598
                 +  ++ G  I  GN++ D ++       KK E    +     E       L   
Sbjct: 202 -----KNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEK 256

Query: 599 LESTLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTP 644
            E       Q  Q +++ + +   +K        ++P+ EEK++TP
Sbjct: 257 EELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETP 302



 Score = 37.4 bits (85), Expect = 0.065
 Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 21/127 (16%)

Query: 5   EEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEYM 64
           ++KKE+K+  F      K+ ++ +  A  +       K D  TV ++P + N   EEE+ 
Sbjct: 43  KKKKEKKKQDFDEDDILKELEELSLEAQGI-------KADRETVAVKPTENN---EEEFT 92

Query: 65  TDEKKKRKSNQLKEIRRTELKRYYSIDDNQNK-THDKKEKKMVVQKPHGTMEYTAGNQDT 123
           + +KKK+     K+          S DDN ++   DK  K     KP   M   + + D 
Sbjct: 93  SKDKKKKGQKGKKQ----------SFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDD 142

Query: 124 LNSIALK 130
            N +  K
Sbjct: 143 FNKLPKK 149


>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
           sapiens]
          Length = 1251

 Score = 38.9 bits (89), Expect = 0.023
 Identities = 45/200 (22%), Positives = 81/200 (40%), Gaps = 12/200 (6%)

Query: 2   DTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEE 61
           +  EE+ E++   +A  K++ +A+  A ++   AT+ H   +  +T   + D C +  EE
Sbjct: 427 EVAEEEAEKEPQDWAETKEEPEAEAEAASSGVPATKQHPEVQVEDT---DADSCPLMAEE 483

Query: 62  ---EYMTDEKKKRKSNQL---KEIRRTELKRYYSIDD--NQNKTHDKKEKKMVVQKPHGT 113
                +       KS+ L        T  K+  S DD   + K     E  +V      T
Sbjct: 484 NPPSTVLPPPSPAKSDTLIVPSSASGTHRKKLPSEDDEAEELKALSPAESPVVAWSDPTT 543

Query: 114 MEYTAGNQDTLNSIALKFNITPNKLVELNKLF-THTIVPGQVLFVPDANSPSSTLRLSSS 172
            + T G     ++ +    I  ++L EL KLF   T    + L  PD  S   + + S +
Sbjct: 544 PKDTDGQDRAASTASTNSAIINDRLQELVKLFKERTEKVKEKLIDPDVTSDEESPKPSPA 603

Query: 173 SPGATVSPSSSDAEYDKLPD 192
                 +P +  AE + + +
Sbjct: 604 KKAPEPAPDTKPAEAEPVEE 623


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 38.9 bits (89), Expect = 0.023
 Identities = 64/283 (22%), Positives = 117/283 (41%), Gaps = 27/283 (9%)

Query: 356  VSEKLK-------KLDSSRETSHGSPTVTKLSKEPSD------TSSAFESTAKENFLGED 402
            V EKLK       K    ++  H  P +    +E  +      T  + E    EN     
Sbjct: 993  VKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIK 1052

Query: 403  DDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTE 462
            D+ +  E+ S +   G H   T+    S D ++  K +S+++ S   +  +  +A L   
Sbjct: 1053 DNILKTEKSSEEDLSGKHDTVTV----SSDLDQFTKDDSKLSISPTALNTEENVACLQNI 1108

Query: 463  NDVELKGALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNK-- 520
              VE      +E   + D   E+     S  ++VE T  +         I   L ++   
Sbjct: 1109 QHVEESVPNGVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVLKQDMAT 1168

Query: 521  EGPQVSENLQKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKE-PDKTWV----KKG 575
            E PQ     Q++ +S+ K +   G   + S+SL+ AG+  + G KE  +K+ +    KK 
Sbjct: 1169 EHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGE--STGKKEVAEKSQINLIDKKW 1226

Query: 576  EPLPVKLNSSTEANVIKEALDSSLESTL-DNSCQGAQMDNKSE 617
            +PL    N +        A++  + +T+ +   QG +++ KS+
Sbjct: 1227 KPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSK 1269


>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 38.1 bits (87), Expect = 0.038
 Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 4/84 (4%)

Query: 3   TKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEE 62
           T ++KK++K +    +KKKK+     +T +    RT T K+   T   E +K     +E+
Sbjct: 31  TTKKKKKKKTT----MKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEK 86

Query: 63  YMTDEKKKRKSNQLKEIRRTELKR 86
               EK+K K  + K+ ++ + K+
Sbjct: 87  EKEKEKEKEKEKKKKKKKKKKKKK 110


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 38.1 bits (87), Expect = 0.038
 Identities = 61/333 (18%), Positives = 119/333 (35%), Gaps = 29/333 (8%)

Query: 300 EDLASEKDINPFSKFK-SINKEKRQQNGEKIMTSDSRPIVPLEKS----TGHTPTKPSGS 354
           +D  SE D N  S+   S N ++ + NG     SDS+     +      T ++ +  +G+
Sbjct: 475 DDANSESDNNSSSRGDASYNSDESKDNGNG---SDSKGAEDDDSDSTSDTNNSDSNGNGN 531

Query: 355 SVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLEEL--- 411
           + ++   K DS +  S  S + +  S   SD+S + +S + ++    D D  D +     
Sbjct: 532 NGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSS 591

Query: 412 ------SSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDV 465
                 SS +       D+     S D  + K   S+  + + +   +S  +   + +  
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSS 651

Query: 466 ELKGALD-LETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQ 524
           +   + D   +    D     D    S  S   N+ +  +  D     E   + +     
Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711

Query: 525 VSENLQKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNS 584
            S++   +  +   S      D + SS+ S + D     N                  + 
Sbjct: 712 SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS-----------DSSD 760

Query: 585 STEANVIKEALDSSLESTLDNSCQGAQMDNKSE 617
           S+ ++   ++ DSS  S   NS       N S+
Sbjct: 761 SSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 38.1 bits (87), Expect = 0.038
 Identities = 55/262 (20%), Positives = 105/262 (40%), Gaps = 32/262 (12%)

Query: 292 ALPSPGEWEDLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEK---STGHTP 348
           A P P +     S+++    +K   + K  + ++ EK+M    +PI    K   +    P
Sbjct: 549 AKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVP 608

Query: 349 TKPSGSSVSEKL--KKLDSSRETSHGSPTVTKLSK-EPSDTSSAFESTAKENFLGEDDDF 405
           +K   S V  ++  K+    +  +    TV K +K +P D     E   KE    ED   
Sbjct: 609 SKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTP 668

Query: 406 VDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDV 465
           +  EE   +      KK+  KE   +  EE+K+ + ++       +V+  +     E   
Sbjct: 669 IKKEEKPKKE---EVKKEVKKE---IKKEEKKEPKKEVKKETPPKEVKKEVK---KEEKK 719

Query: 466 ELKGALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQV 525
           E+K   + E  ++   +P+  K+S +P S  +    +   +                P+ 
Sbjct: 720 EVKKE-EKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKV----------------PKK 762

Query: 526 SENLQKTELSDGKSIEPGGIDI 547
            E+++K  ++ GK  E G I +
Sbjct: 763 EESVKKDSVAAGKPKEKGKIKV 784



 Score = 31.6 bits (70), Expect = 3.6
 Identities = 22/105 (20%), Positives = 50/105 (47%), Gaps = 4/105 (3%)

Query: 5   EEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEYM 64
           +EK  +K++      KK++ ++  +  +    +T   KE+      + ++    V++E  
Sbjct: 634 KEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKP----KKEEVKKEVKKEIK 689

Query: 65  TDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQK 109
            +EKK+ K    KE    E+K+    ++ +    ++KE K  ++K
Sbjct: 690 KEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKK 734


>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
          Length = 1235

 Score = 38.1 bits (87), Expect = 0.038
 Identities = 53/223 (23%), Positives = 101/223 (45%), Gaps = 30/223 (13%)

Query: 422 KDTLKECLSLDPEE--RKKAESQINNSAVEMQVQSALAFLG----TENDVELKGALDLET 475
           KDT+ + + L  +E   K+A  Q  +S V +  +     LG    T+ DV    +  + T
Sbjct: 492 KDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSDVIGT 551

Query: 476 CEKQDIMPEVDKQSG--SPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENLQKTE 533
           CE  D+  +VD+ S   +  +  +  + + + L    ++       KE P + E ++  E
Sbjct: 552 CEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVP-IKEIVEMNE 610

Query: 534 LSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEANVIKE 593
           + +GK+ E       ++SS     + I + N+EP  T   +GE   +  +SSTE   ++ 
Sbjct: 611 IEEGKNKEQ-----AINSS-----ENIMDINEEPGTT---EGE--EITESSSTEEMEVRS 655

Query: 594 ALDSSLESTLDNSCQGA-----QMD-NKSEVQLWLLKRIQVPI 630
            +  + +  L +  Q A     Q+D  K E+ + + K  +V +
Sbjct: 656 VVADTDQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEPEVTV 698



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 108/525 (20%), Positives = 196/525 (37%), Gaps = 100/525 (19%)

Query: 2   DTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEP--------- 52
           D KEE +E +      +   K+A  +   AS+        K   N  +LE          
Sbjct: 317 DGKEEDEEEETENSLPIPASKRASSDLSIASS-----EEDKLSQNACILESVSEKTERSN 371

Query: 53  --DKCNIAV-EEEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQN--KTHDKKEKKMVV 107
             DK N  +  E+  TDE +K   +  + I   +L+    + D     K ++++++  + 
Sbjct: 372 SEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTAVIKENEREKRPKLE 431

Query: 108 QKP----HGTMEYTAGNQDTLNSI--ALKFNITPN------KLVELNKLFTHTIVPGQVL 155
             P      T++  + ++   N+I   L+ NI  N      K  E  ++F + ++  + +
Sbjct: 432 NLPDTEDQETVDINSVSEGKENNIMITLETNIEHNLKSEEEKDQEKQQMFENKLIKSEEI 491

Query: 156 FVPDANSPSSTLRLSSSSPG---ATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSE 212
                ++   T+ L S   G   A +    S+    K    +   +  K  + V+S+TS+
Sbjct: 492 ----KDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSD 547

Query: 213 -------EDEPGVVKFLKMNCRYFTDGKGVVG-GVMIVTPNNIMFDPHKSDPLVIENGCE 264
                   D    V           DGK VV  G  ++  N  M  P          G +
Sbjct: 548 VIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLI--NKPMVGPEAG-------GTK 598

Query: 265 EYGLICPMEEVVSIALYNDISHMKIKDALPSPGEWEDLASEKDINPFSKFKSINKEKRQQ 324
           E     P++E+V +   N+I   K K              E+ IN       IN+E    
Sbjct: 599 EV----PIKEIVEM---NEIEEGKNK--------------EQAINSSENIMDINEEPGTT 637

Query: 325 NGEKIMTSDSRPIVPLEKSTGHTPTKPSGSSVSEKLK---KLDSSRE----TSHGSPTVT 377
            GE+I  S S   + +      T  K  GS V +  K   ++D  ++    +    P VT
Sbjct: 638 EGEEITESSSTEEMEVRSVVADTDQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEPEVT 697

Query: 378 KLSKEPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERK 437
            +S+          S    +  GE+ + +          G + K +T+    S +P+E  
Sbjct: 698 VVSQPTEPQPVLIPSININSDSGENKEEI----------GSLSKTETILPPESENPKEND 747

Query: 438 K---AESQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQ 479
                 S  + S++++ + S  +FL    D    G++ L+   +Q
Sbjct: 748 NDSGTGSTADTSSIDLNL-SISSFLSKTKD---SGSISLQETRRQ 788


>gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sapiens]
          Length = 1827

 Score = 37.0 bits (84), Expect = 0.086
 Identities = 70/351 (19%), Positives = 148/351 (42%), Gaps = 49/351 (13%)

Query: 341  EKSTGHTPTKPSGSSVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAK----- 395
            ++++ H     SG S     K+ D  ++ +    TV + S+E +D+    + T +     
Sbjct: 933  KEASAHISGDKSGLS-----KEFDQEKKANDRLDTVLEKSEEHADSKEHAKKTEEAGDEI 987

Query: 396  ENF-LGEDDDFVDLEELSSQTGGGMHKKD----TLKECLSLDPEERKKAESQINNSAVEM 450
            E F LG   +    ++LS  T     K +    ++ E   ++P   KK E  ++  AV+ 
Sbjct: 988  ETFGLGVTYEQALAKDLSIPTDASSEKAEKGLSSVPEIAEVEPS--KKVEQGLD-FAVQG 1044

Query: 451  QVQSALAFLGTENDVELKGALDLETCEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVK 510
            Q+   ++  G     ++   L+++     ++  E   Q  +P S+     +    ++   
Sbjct: 1045 QLDVKISDFG-----QMASGLNIDDRRATELKLEAT-QDMTPSSKAPQEADAFMGVESGH 1098

Query: 511  LIEYYLTKNKEGPQVSENLQKTELSDGKSIEPGGIDITLSSSLSQAGDPITEGNKEPDKT 570
            +        KEG +VSE   K +++    +    +D   S   S   + +T  + + D+ 
Sbjct: 1099 M--------KEGTKVSETEVKEKVAKPDLVHQEAVDKEESYESSGEHESLTMESLKADEG 1150

Query: 571  WVKKGEPLPVKLNSSTEANVIKEALDSSLESTLDNSCQGAQMDNKSEVQLWLLKRIQVPI 630
                      K  +S E+++I++ +  +++ +++  C  A     SE  L   +R  V +
Sbjct: 1151 ----------KKETSPESSLIQDEI--AVKLSVEIPCPPAV----SEADLATDERADVQM 1194

Query: 631  EDILPSKEEKSKTPPMFLC-IKVGKPMRKSFATHTAAMVQQYGKRRKQPEY 680
            E I   KEE  +TP + +    V +P+ ++  +  A +  +  +   Q EY
Sbjct: 1195 EFIQGPKEESKETPDISITPSDVAEPLHETIVSEPAEIQSEEEEIEAQGEY 1245



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 28/105 (26%), Positives = 45/105 (42%), Gaps = 12/105 (11%)

Query: 290  KDALPSPGEW----EDLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVPLEKSTG 345
            + +LP P         ++ ++D N FS   SI+   R+       T+ S PI    KS  
Sbjct: 1538 RSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARR-------TTRSEPIRRAGKSGT 1590

Query: 346  HTPTKPSGSSVSEKLKKLDSSRET-SHGSPTVTKLSKEPSDTSSA 389
             TPT P  ++++       SSR   + G+P+  +    P    SA
Sbjct: 1591 STPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSA 1635


>gi|114326455 chromodomain helicase DNA binding protein 8 [Homo
            sapiens]
          Length = 2302

 Score = 37.0 bits (84), Expect = 0.086
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 3/131 (2%)

Query: 335  RPIVPLEKSTGHTPTK-PSGSSVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSAFEST 393
            RP  P+EKS   T T+ PS  S++ KL+    +R  S  +P   ++   PSDT+     +
Sbjct: 1721 RPDAPVEKSPEETATQVPSLESLTLKLEHEVVAR--SRPTPQDYEMRVSPSDTTPLVSRS 1778

Query: 394  AKENFLGEDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQ 453
                 L ++DD     +LS  +        +     S D  E +K E   + S  ++  +
Sbjct: 1779 VPPVKLEDEDDSDSELDLSKLSPSSSSSSSSSSSSSSTDESEDEKEEKLTDQSRSKLYDE 1838

Query: 454  SALAFLGTEND 464
             +L  L    D
Sbjct: 1839 ESLLSLTMSQD 1849



 Score = 32.0 bits (71), Expect = 2.8
 Identities = 19/59 (32%), Positives = 30/59 (50%)

Query: 20  KKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEYMTDEKKKRKSNQLKE 78
           +KKQ K N   A A+A     G+++   V+ E +  ++  EEE     +KK    +LKE
Sbjct: 176 QKKQEKANRIVAEAIARARARGEQNIPRVLNEDELPSVRPEEEGEKKRRKKSAGERLKE 234



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 24/119 (20%)

Query: 6   EKKERKQSYFARLKKKKQAKQNAETASAVATRTH-------TGKE-------DNNTVVLE 51
           EKK RK+S   RLK++K  K     AS    ++         GK+       DN+ V + 
Sbjct: 220 EKKRRKKSAGERLKEEKPKKSKTSGASKTKGKSKLNTITPVVGKKRKRNTSSDNSDVEVM 279

Query: 52  PDKCNIAVEEEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKP 110
           P +   +  E+  +  +K+R + Q+K       ++ Y+ D +   T D++E+++ V  P
Sbjct: 280 PAQ---SPREDEESSIQKRRSNRQVK-------RKKYTEDLDIKITDDEEEEEVDVTGP 328


>gi|169646281 coiled-coil domain containing 14 [Homo sapiens]
          Length = 912

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 50/239 (20%), Positives = 101/239 (42%), Gaps = 14/239 (5%)

Query: 418 GMHKKDTLKECLS--LDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKGALDLET 475
           G+HK+  L +C+   L        E+ +++       QS  AFL T  +   +  +   T
Sbjct: 299 GIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIREAT 358

Query: 476 CEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKE--GPQVSENLQK-- 531
            E++D+   +  +       V+   N+++  +KV++I+Y L + K     Q    +Q+  
Sbjct: 359 SERKDL--NIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLI 416

Query: 532 TELSDGKSIEP---GGIDITLSSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEA 588
           TE+    S+ P   G  DI +  +L  A  P+   N +  +      + L  +  +   +
Sbjct: 417 TEMEACISVLPTVSGNTDIQVEIAL--AMQPLRSENAQLRRQLRILNQQLREQQKTQKPS 474

Query: 589 NVIKEALDSSLESTLDNSCQGAQMDNKSEVQLWLLKRIQVPIEDILPSKEEKSKTPPMF 647
             +   L+     +L+ S Q  Q++   + Q  L  + +  ++ I   K+E  K   +F
Sbjct: 475 GAVDCNLELFSLQSLNMSLQN-QLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIF 532


>gi|45439327 periplakin [Homo sapiens]
          Length = 1756

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 43/178 (24%), Positives = 78/178 (43%), Gaps = 24/178 (13%)

Query: 354  SSVSEKLKKLDSSRETSHGSPTVTKLSK---------EPSDTSSAFESTAKENFLGEDDD 404
            S + +KLK+L+  R  + G  TV ++ K         E SD +  +E  A +    + + 
Sbjct: 1092 SFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREK 1151

Query: 405  FVDLEEL--SSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTE 462
               L ++    +    +  ++ ++E +  DP    KAES++ N  +E+ V+    + G E
Sbjct: 1152 TELLRKIWALEEENAKVVVQEKVREIVRPDP----KAESEVANLRLEL-VEQERKYRGAE 1206

Query: 463  NDVELKGALDLET-------CEKQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIE 513
              +    + +LE         E +++  EV K    PE   E      E +DK +LIE
Sbjct: 1207 EQLRSYQS-ELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIE 1263


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 4/92 (4%)

Query: 4   KEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEY 63
           +E  +E ++ +   LKK K  +Q AE  +A      T  ++     +EP++C I  E   
Sbjct: 134 EEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQ----MEPERCRIQTEFNQ 189

Query: 64  MTDEKKKRKSNQLKEIRRTELKRYYSIDDNQN 95
           + +   + +  +LK++ + E K    I++ +N
Sbjct: 190 LRNILDRVEQRELKKLEQEEKKGLRIIEEAEN 221


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 4/92 (4%)

Query: 4   KEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEY 63
           +E  +E ++ +   LKK K  +Q AE  +A      T  ++     +EP++C I  E   
Sbjct: 162 EEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQ----MEPERCRIQTEFNQ 217

Query: 64  MTDEKKKRKSNQLKEIRRTELKRYYSIDDNQN 95
           + +   + +  +LK++ + E K    I++ +N
Sbjct: 218 LRNILDRVEQRELKKLEQEEKKGLRIIEEAEN 249


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 51/221 (23%), Positives = 85/221 (38%), Gaps = 31/221 (14%)

Query: 3   TKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLE---PDKCNIAV 59
           TKEE K  ++   A+  +K++AK   +  S V     + ++  + V  E   P+K    V
Sbjct: 642 TKEEAKSPEK---AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698

Query: 60  EEEYMTDEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAG 119
           +EE  + EK K   + +KE  ++  K    +          KE+    +K    ++  A 
Sbjct: 699 KEEAKSPEKAK---SPVKEEAKSPEKAKSPV----------KEEAKTPEKAKSPVKEEAK 745

Query: 120 NQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVS 179
           + +   S        P K   L+        P +     +A SP+      + SP     
Sbjct: 746 SPEKAKS--------PEKAKTLDVKSPEAKTPAK----EEARSPADKFPEKAKSPVKEEV 793

Query: 180 PSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVK 220
            S   A+     DA    K +   E V S   EE++P  VK
Sbjct: 794 KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVK 834


>gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]
          Length = 1090

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 13/121 (10%)

Query: 328 KIMTSDSRPIVPLEKSTGHTPTKPSGS-----SVSEKLKKLDSSRETSH-GSPTVTKLSK 381
           ++  S   P+   E++ GH+P++P  +      V        SSR +S  G  T+T L K
Sbjct: 347 ELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKK 406

Query: 382 EPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAES 441
           E      AF    K + L EDD+  + E+        + K    +E L L+ E R+   S
Sbjct: 407 EAKFELRAFHEDKKPSKLFEDDEH-EKEQYC------IRKVRPSEEMLELEKERRELIRS 459

Query: 442 Q 442
           Q
Sbjct: 460 Q 460


>gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]
          Length = 1103

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 13/121 (10%)

Query: 328 KIMTSDSRPIVPLEKSTGHTPTKPSGS-----SVSEKLKKLDSSRETSH-GSPTVTKLSK 381
           ++  S   P+   E++ GH+P++P  +      V        SSR +S  G  T+T L K
Sbjct: 347 ELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKK 406

Query: 382 EPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAES 441
           E      AF    K + L EDD+  + E+        + K    +E L L+ E R+   S
Sbjct: 407 EAKFELRAFHEDKKPSKLFEDDEH-EKEQYC------IRKVRPSEEMLELEKERRELIRS 459

Query: 442 Q 442
           Q
Sbjct: 460 Q 460


>gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo
           sapiens]
          Length = 859

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 13/121 (10%)

Query: 328 KIMTSDSRPIVPLEKSTGHTPTKPSGS-----SVSEKLKKLDSSRETSH-GSPTVTKLSK 381
           ++  S   P+   E++ GH+P++P  +      V        SSR +S  G  T+T L K
Sbjct: 116 ELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKK 175

Query: 382 EPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAES 441
           E      AF    K + L EDD+  + E+        + K    +E L L+ E R+   S
Sbjct: 176 EAKFELRAFHEDKKPSKLFEDDEH-EKEQYC------IRKVRPSEEMLELEKERRELIRS 228

Query: 442 Q 442
           Q
Sbjct: 229 Q 229


>gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo
           sapiens]
          Length = 948

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 13/121 (10%)

Query: 328 KIMTSDSRPIVPLEKSTGHTPTKPSGS-----SVSEKLKKLDSSRETSH-GSPTVTKLSK 381
           ++  S   P+   E++ GH+P++P  +      V        SSR +S  G  T+T L K
Sbjct: 205 ELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKK 264

Query: 382 EPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMHKKDTLKECLSLDPEERKKAES 441
           E      AF    K + L EDD+  + E+        + K    +E L L+ E R+   S
Sbjct: 265 EAKFELRAFHEDKKPSKLFEDDEH-EKEQYC------IRKVRPSEEMLELEKERRELIRS 317

Query: 442 Q 442
           Q
Sbjct: 318 Q 318


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score = 36.2 bits (82), Expect = 0.15
 Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 4/92 (4%)

Query: 4   KEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEY 63
           +E  +E ++ +   LKK K  +Q AE  +A      T  ++     +EP++C I  E   
Sbjct: 162 EEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQ----MEPERCRIQTEFNQ 217

Query: 64  MTDEKKKRKSNQLKEIRRTELKRYYSIDDNQN 95
           + +   + +  +LK++ + E K    I++ +N
Sbjct: 218 LRNILDRVEQRELKKLEQEEKKGLRIIEEAEN 249


>gi|18921093 transient receptor potential cation channel, subfamily M,
            member 6 [Homo sapiens]
          Length = 2022

 Score = 35.8 bits (81), Expect = 0.19
 Identities = 50/158 (31%), Positives = 65/158 (41%), Gaps = 27/158 (17%)

Query: 478  KQDIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENLQKTELSDG 537
            +QDI  EV          V +  ++ E  +K + I + L    +  QV   L  T     
Sbjct: 1376 EQDIQTEVLVHLTGQTPVVSDWASVDEPKEKHEPIAHLLDGQDKAEQVLPTLSCTP---- 1431

Query: 538  KSIEPGGIDITLSSSLSQAGDPITEGN------KEPDKTWV----KKGE---PLPVKLNS 584
               EP    +T+SS LSQA    T G        E D+T V    KK +   P     +S
Sbjct: 1432 ---EP----MTMSSPLSQAKIMQTGGGYVNWAFSEGDETGVFSIKKKWQTCLPSTCDSDS 1484

Query: 585  STEANVIKEALDSSLESTLDNSCQGAQMDNKSEVQLWL 622
            S      K+A DSSL    DNS + AQ    SEV  WL
Sbjct: 1485 SRSEQHQKQAQDSSLS---DNSTRSAQSSECSEVGPWL 1519


>gi|7657544 sodium channel, voltage gated, type VIII, alpha [Homo
           sapiens]
          Length = 1980

 Score = 35.8 bits (81), Expect = 0.19
 Identities = 42/201 (20%), Positives = 84/201 (41%), Gaps = 28/201 (13%)

Query: 6   EKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEYMT 65
           E+ E+K++ F  + ++ + +Q    A+A+AT   T  ED             A+EEE   
Sbjct: 423 EEAEQKEAEFKAMLEQLKKQQEEAQAAAMATSAGTVSED-------------AIEEEGEE 469

Query: 66  DEKKKRKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAGNQDTLN 125
                R S+++ ++     K      + +N+   +K+K++   +  G  E    ++    
Sbjct: 470 GGGSPRSSSEISKLSSKSAK------ERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDG 523

Query: 126 SIALKFNITPNKLVELNKLFTHTI--VPGQVLFVPDANSPSSTLRLSSSSPGATVSPSS- 182
                F +  N++     +   ++  +PG   F+   NS SS    S   PG    P S 
Sbjct: 524 MRRKAFRLPDNRIGRKFSIMNQSLLSIPGSP-FLSRHNSKSSI--FSFRGPGRFRDPGSE 580

Query: 183 ---SDAEYDKLPDADLARKAL 200
              +D E+  + +++  R +L
Sbjct: 581 NEFADDEHSTVEESEGRRDSL 601


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,301,449
Number of Sequences: 37866
Number of extensions: 1787709
Number of successful extensions: 6555
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 140
Number of HSP's that attempted gapping in prelim test: 6147
Number of HSP's gapped (non-prelim): 531
length of query: 931
length of database: 18,247,518
effective HSP length: 112
effective length of query: 819
effective length of database: 14,006,526
effective search space: 11471344794
effective search space used: 11471344794
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.