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Search of human proteins with 170784867
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
sapiens]
(860 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 1728 0.0
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 1573 0.0
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 72 2e-12
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 72 2e-12
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 69 2e-11
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 69 2e-11
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 69 2e-11
gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 64 8e-10
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 63 1e-09
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 63 1e-09
gi|83415184 transmembrane and tetratricopeptide repeat containin... 61 4e-09
gi|195963398 suppressor of G2 allele of SKP1 isoform a [Homo sap... 57 7e-08
gi|27262638 sperm associated antigen 1 [Homo sapiens] 55 3e-07
gi|27262636 sperm associated antigen 1 [Homo sapiens] 55 3e-07
gi|5730041 suppressor of G2 allele of SKP1 isoform b [Homo sapiens] 54 5e-07
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 54 5e-07
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 54 5e-07
gi|116534937 interferon-induced protein with tetratricopeptide r... 53 1e-06
gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ... 51 4e-06
gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo ... 51 4e-06
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 50 7e-06
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 50 1e-05
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 50 1e-05
gi|58330892 interferon-induced protein with tetratricopeptide re... 49 2e-05
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 49 3e-05
gi|224809432 transmembrane and tetratricopeptide repeat containi... 47 6e-05
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 46 1e-04
gi|56606133 tetratricopeptide repeat domain 32 [Homo sapiens] 45 3e-04
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 45 4e-04
gi|212549738 anaphase-promoting complex subunit 7 isoform b [Hom... 45 4e-04
>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
sapiens]
Length = 860
Score = 1728 bits (4475), Expect = 0.0
Identities = 860/860 (100%), Positives = 860/860 (100%)
Query: 1 MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQ 60
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQ
Sbjct: 1 MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQ 60
Query: 61 HRQQQEAPAGGGGCSPQSGDWGDQYSAECGESSFLNFHDSDCEPKGSSPCDSLLSLNTEK 120
HRQQQEAPAGGGGCSPQSGDWGDQYSAECGESSFLNFHDSDCEPKGSSPCDSLLSLNTEK
Sbjct: 61 HRQQQEAPAGGGGCSPQSGDWGDQYSAECGESSFLNFHDSDCEPKGSSPCDSLLSLNTEK 120
Query: 121 ILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI 180
ILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI
Sbjct: 121 ILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI 180
Query: 181 YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLT 240
YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLT
Sbjct: 181 YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLT 240
Query: 241 KAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLK 300
KAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLK
Sbjct: 241 KAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLK 300
Query: 301 EAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMM 360
EAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMM
Sbjct: 301 EAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMM 360
Query: 361 LYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQ 420
LYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQ
Sbjct: 361 LYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQ 420
Query: 421 KASPEYLKVKYLREYSRYLHAHLDTPLTEYNIDVDLPGSFKDHWAKNLPFLIEDYEEQPG 480
KASPEYLKVKYLREYSRYLHAHLDTPLTEYNIDVDLPGSFKDHWAKNLPFLIEDYEEQPG
Sbjct: 421 KASPEYLKVKYLREYSRYLHAHLDTPLTEYNIDVDLPGSFKDHWAKNLPFLIEDYEEQPG 480
Query: 481 LQPHIKDVLHQNFESYKPEVQELICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQ 540
LQPHIKDVLHQNFESYKPEVQELICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQ
Sbjct: 481 LQPHIKDVLHQNFESYKPEVQELICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQ 540
Query: 541 AVQRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNH 600
AVQRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNH
Sbjct: 541 AVQRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNH 600
Query: 601 INLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIM 660
INLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIM
Sbjct: 601 INLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIM 660
Query: 661 KQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHA 720
KQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHA
Sbjct: 661 KQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHA 720
Query: 721 EIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGA 780
EIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGA
Sbjct: 721 EIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGA 780
Query: 781 LMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKVAKSWMNLKSISPSYKTLPSVSETFPT 840
LMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKVAKSWMNLKSISPSYKTLPSVSETFPT
Sbjct: 781 LMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKVAKSWMNLKSISPSYKTLPSVSETFPT 840
Query: 841 LRSMIEVLNTDSSPRCLKKL 860
LRSMIEVLNTDSSPRCLKKL
Sbjct: 841 LRSMIEVLNTDSSPRCLKKL 860
>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
sapiens]
Length = 807
Score = 1573 bits (4072), Expect = 0.0
Identities = 795/860 (92%), Positives = 798/860 (92%), Gaps = 53/860 (6%)
Query: 1 MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQ 60
MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQ
Sbjct: 1 MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQ 60
Query: 61 HRQQQEAPAGGGGCSPQSGDWGDQYSAECGESSFLNFHDSDCEPKGSSPCDSLLSLNTEK 120
HRQQQEAPAGGGGCSPQSGDWGDQYSAECGESSFLNFHDSDCEPKGSSPCDSLLSLNTEK
Sbjct: 61 HRQQQEAPAGGGGCSPQSGDWGDQYSAECGESSFLNFHDSDCEPKGSSPCDSLLSLNTEK 120
Query: 121 ILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAI 180
ILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIG S +
Sbjct: 121 ILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIG----------------------SGL 158
Query: 181 YGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLT 240
Y I + F +ILSPLGRINEAVNDLT
Sbjct: 159 YDEAIRH-------------------------------FSTMLQILSPLGRINEAVNDLT 187
Query: 241 KAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLK 300
KAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLK
Sbjct: 188 KAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLK 247
Query: 301 EAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMM 360
EAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMM
Sbjct: 248 EAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMM 307
Query: 361 LYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQ 420
LYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQ
Sbjct: 308 LYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQ 367
Query: 421 KASPEYLKVKYLREYSRYLHAHLDTPLTEYNIDVDLPGSFKDHWAKNLPFLIEDYEEQPG 480
KASPEYLKVKYLREYSRYLHAHLDTPLTEYNIDVDLPGSFKDHWAKNLPFLIEDYEEQPG
Sbjct: 368 KASPEYLKVKYLREYSRYLHAHLDTPLTEYNIDVDLPGSFKDHWAKNLPFLIEDYEEQPG 427
Query: 481 LQPHIKDVLHQNFESYKPEVQELICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQ 540
LQPHIKDVLHQNFESYKPEVQELICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQ
Sbjct: 428 LQPHIKDVLHQNFESYKPEVQELICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQ 487
Query: 541 AVQRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNH 600
AVQRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNH
Sbjct: 488 AVQRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNH 547
Query: 601 INLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIM 660
INLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIM
Sbjct: 548 INLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIM 607
Query: 661 KQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHA 720
KQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHA
Sbjct: 608 KQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHA 667
Query: 721 EIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGA 780
EIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGA
Sbjct: 668 EIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGA 727
Query: 781 LMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKVAKSWMNLKSISPSYKTLPSVSETFPT 840
LMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKVAKSWMNLKSISPSYKTLPSVSETFPT
Sbjct: 728 LMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKVAKSWMNLKSISPSYKTLPSVSETFPT 787
Query: 841 LRSMIEVLNTDSSPRCLKKL 860
LRSMIEVLNTDSSPRCLKKL
Sbjct: 788 LRSMIEVLNTDSSPRCLKKL 807
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 72.0 bits (175), Expect = 2e-12
Identities = 58/267 (21%), Positives = 119/267 (44%), Gaps = 6/267 (2%)
Query: 117 NTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDL 176
N K Q + E R D + + +A L+ +G + A++ + + LQ PDL
Sbjct: 87 NVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDL 146
Query: 177 VSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAV 236
G K L ++ A+ + I +P+ + + + G I A+
Sbjct: 147 YCVRSDLGNLL--KALGRLEEAKACYL---KAIETQPNFAVAWSNLGCVFNAQGEIWLAI 201
Query: 237 NDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFH 295
+ KA+ L P+ Y + G + + + A + ++L L+ N + ++
Sbjct: 202 HHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYE 261
Query: 296 RGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQ 355
+GL+ AI++++ A++ + F DAY +L A +E G+ A + + AL L H +L
Sbjct: 262 QGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLN 321
Query: 356 LRGMMLYHHGSLQEALKNFKRCLQLEP 382
+ G+++EA++ +++ L++ P
Sbjct: 322 NLANIKREQGNIEEAVRLYRKALEVFP 348
Score = 71.6 bits (174), Expect = 3e-12
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Query: 165 HFSTM-LQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRA 223
HFST+ +++ P L A G Y ++G + A+ + L+PD + + A
Sbjct: 66 HFSTLAIKQNPLLAEAYSNLGNVYKERG-----QLQEAIEHYRHALRLKPDFIDGYINLA 120
Query: 224 EILSPLGRINEAVNDLTKAIQLQPSARLYRHR-GTLYFISEDYATAHEDFQQSLELNKNQ 282
L G + AV A+Q P R G L A + +++E N
Sbjct: 121 AALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNF 180
Query: 283 PIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQK 342
+A G F +G + AI F++A+ +F+DAY +LG +E F+ A ++ +
Sbjct: 181 AVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLR 240
Query: 343 ALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPY 383
AL L+ NH + Y G + A+ ++R ++L+P+
Sbjct: 241 ALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPH 281
Score = 68.2 bits (165), Expect = 3e-11
Identities = 57/246 (23%), Positives = 107/246 (43%), Gaps = 25/246 (10%)
Query: 150 AYVLIGSGL-----YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFE 204
AY+ +G+ L +D A+ + L P+ Y ++GL D LA+
Sbjct: 217 AYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLID-----LAIDT 271
Query: 205 LSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS--------ARLYRHRG 256
R I L+P P+ + A L G + EA + A++L P+ A + R +G
Sbjct: 272 YRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQG 331
Query: 257 TLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDF 316
+ Y A E F + + N + +G L+EA+ +KEA++ F
Sbjct: 332 NIEEAVRLYRKALEVFPEFAAAHSNLASVLQ-------QQGKLQEALMHYKEAIRISPTF 384
Query: 317 IDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKR 376
DAY ++G +E+ + + A + + +A+ +N + G++ EA+ +++
Sbjct: 385 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRT 444
Query: 377 CLQLEP 382
L+L+P
Sbjct: 445 ALKLKP 450
Score = 60.5 bits (145), Expect = 7e-09
Identities = 43/144 (29%), Positives = 68/144 (47%), Gaps = 2/144 (1%)
Query: 275 SLELNKNQPIAMLYKGL--TFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGN 332
+L + +N +A Y L + RG L+EAIE ++ AL+ K DFID Y +L A G+
Sbjct: 69 TLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGD 128
Query: 333 FEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKG 392
E A +++ AL N + G +L G L+EA + + ++ +P V G
Sbjct: 129 MEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLG 188
Query: 393 LSHVAMGQFYEGIKAQTKVMLNDP 416
A G+ + I K + DP
Sbjct: 189 CVFNAQGEIWLAIHHFEKAVTLDP 212
Score = 52.4 bits (124), Expect = 2e-06
Identities = 45/194 (23%), Positives = 90/194 (46%), Gaps = 7/194 (3%)
Query: 197 NAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHR 255
N E A+ + + + P+ A +L G++ EA+ +AI++ P+ A Y +
Sbjct: 332 NIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNM 391
Query: 256 GTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHR--GLLKEAIESFKEALKQK 313
G +D A + + +++++N A + L H+ G + EAI S++ ALK K
Sbjct: 392 GNTLKEMQDVQGALQCYTRAIQINP--AFADAHSNLASIHKDSGNIPEAIASYRTALKLK 449
Query: 314 VDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKN 373
DF DAY +L + + ++ E +K + + + ++ +L + HH L
Sbjct: 450 PDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVH-PHHSMLYPLSHG 508
Query: 374 FKRCLQLEPYNEVC 387
F++ + E + +C
Sbjct: 509 FRKAI-AERHGNLC 521
Score = 52.0 bits (123), Expect = 2e-06
Identities = 54/262 (20%), Positives = 104/262 (39%), Gaps = 15/262 (5%)
Query: 156 SGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-DIKNAELALFELSRVITLEPD 214
+G ++ A RH + ++EPD G+ +H + + + + I P
Sbjct: 24 AGDFEAAERHCMQLWRQEPD------NTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPL 77
Query: 215 RPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQ 273
E + + G++ EA+ A++L+P Y + + D A + +
Sbjct: 78 LAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYV 137
Query: 274 QSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNF 333
+L+ N + G G L+EA + +A++ + +F A+ +LG + G
Sbjct: 138 SALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEI 197
Query: 334 EAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQ----- 388
A F+KA+ L+ N + G +L A+ + R L L P + V
Sbjct: 198 WLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLAC 257
Query: 389 --YMKGLSHVAMGQFYEGIKAQ 408
Y +GL +A+ + I+ Q
Sbjct: 258 VYYEQGLIDLAIDTYRRAIELQ 279
Score = 33.9 bits (76), Expect = 0.66
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 5/99 (5%)
Query: 149 IAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRV 208
+A VL G EA+ H+ ++ P A G L ++++ + AL +R
Sbjct: 357 LASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMG-----NTLKEMQDVQGALQCYTRA 411
Query: 209 ITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQP 247
I + P + A I G I EA+ A++L+P
Sbjct: 412 IQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 450
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 72.0 bits (175), Expect = 2e-12
Identities = 58/267 (21%), Positives = 119/267 (44%), Gaps = 6/267 (2%)
Query: 117 NTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDL 176
N K Q + E R D + + +A L+ +G + A++ + + LQ PDL
Sbjct: 97 NVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDL 156
Query: 177 VSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAV 236
G K L ++ A+ + I +P+ + + + G I A+
Sbjct: 157 YCVRSDLGNLL--KALGRLEEAKACYL---KAIETQPNFAVAWSNLGCVFNAQGEIWLAI 211
Query: 237 NDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFH 295
+ KA+ L P+ Y + G + + + A + ++L L+ N + ++
Sbjct: 212 HHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYE 271
Query: 296 RGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQ 355
+GL+ AI++++ A++ + F DAY +L A +E G+ A + + AL L H +L
Sbjct: 272 QGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLN 331
Query: 356 LRGMMLYHHGSLQEALKNFKRCLQLEP 382
+ G+++EA++ +++ L++ P
Sbjct: 332 NLANIKREQGNIEEAVRLYRKALEVFP 358
Score = 71.6 bits (174), Expect = 3e-12
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Query: 165 HFSTM-LQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRA 223
HFST+ +++ P L A G Y ++G + A+ + L+PD + + A
Sbjct: 76 HFSTLAIKQNPLLAEAYSNLGNVYKERG-----QLQEAIEHYRHALRLKPDFIDGYINLA 130
Query: 224 EILSPLGRINEAVNDLTKAIQLQPSARLYRHR-GTLYFISEDYATAHEDFQQSLELNKNQ 282
L G + AV A+Q P R G L A + +++E N
Sbjct: 131 AALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNF 190
Query: 283 PIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQK 342
+A G F +G + AI F++A+ +F+DAY +LG +E F+ A ++ +
Sbjct: 191 AVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLR 250
Query: 343 ALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPY 383
AL L+ NH + Y G + A+ ++R ++L+P+
Sbjct: 251 ALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPH 291
Score = 68.2 bits (165), Expect = 3e-11
Identities = 57/246 (23%), Positives = 107/246 (43%), Gaps = 25/246 (10%)
Query: 150 AYVLIGSGL-----YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFE 204
AY+ +G+ L +D A+ + L P+ Y ++GL D LA+
Sbjct: 227 AYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLID-----LAIDT 281
Query: 205 LSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS--------ARLYRHRG 256
R I L+P P+ + A L G + EA + A++L P+ A + R +G
Sbjct: 282 YRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQG 341
Query: 257 TLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDF 316
+ Y A E F + + N + +G L+EA+ +KEA++ F
Sbjct: 342 NIEEAVRLYRKALEVFPEFAAAHSNLASVLQ-------QQGKLQEALMHYKEAIRISPTF 394
Query: 317 IDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKR 376
DAY ++G +E+ + + A + + +A+ +N + G++ EA+ +++
Sbjct: 395 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRT 454
Query: 377 CLQLEP 382
L+L+P
Sbjct: 455 ALKLKP 460
Score = 60.5 bits (145), Expect = 7e-09
Identities = 43/144 (29%), Positives = 68/144 (47%), Gaps = 2/144 (1%)
Query: 275 SLELNKNQPIAMLYKGL--TFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGN 332
+L + +N +A Y L + RG L+EAIE ++ AL+ K DFID Y +L A G+
Sbjct: 79 TLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGD 138
Query: 333 FEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKG 392
E A +++ AL N + G +L G L+EA + + ++ +P V G
Sbjct: 139 MEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLG 198
Query: 393 LSHVAMGQFYEGIKAQTKVMLNDP 416
A G+ + I K + DP
Sbjct: 199 CVFNAQGEIWLAIHHFEKAVTLDP 222
Score = 52.4 bits (124), Expect = 2e-06
Identities = 45/194 (23%), Positives = 90/194 (46%), Gaps = 7/194 (3%)
Query: 197 NAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHR 255
N E A+ + + + P+ A +L G++ EA+ +AI++ P+ A Y +
Sbjct: 342 NIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNM 401
Query: 256 GTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHR--GLLKEAIESFKEALKQK 313
G +D A + + +++++N A + L H+ G + EAI S++ ALK K
Sbjct: 402 GNTLKEMQDVQGALQCYTRAIQINP--AFADAHSNLASIHKDSGNIPEAIASYRTALKLK 459
Query: 314 VDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKN 373
DF DAY +L + + ++ E +K + + + ++ +L + HH L
Sbjct: 460 PDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVH-PHHSMLYPLSHG 518
Query: 374 FKRCLQLEPYNEVC 387
F++ + E + +C
Sbjct: 519 FRKAI-AERHGNLC 531
Score = 52.0 bits (123), Expect = 2e-06
Identities = 54/262 (20%), Positives = 104/262 (39%), Gaps = 15/262 (5%)
Query: 156 SGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-DIKNAELALFELSRVITLEPD 214
+G ++ A RH + ++EPD G+ +H + + + + I P
Sbjct: 34 AGDFEAAERHCMQLWRQEPD------NTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPL 87
Query: 215 RPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQ 273
E + + G++ EA+ A++L+P Y + + D A + +
Sbjct: 88 LAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYV 147
Query: 274 QSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNF 333
+L+ N + G G L+EA + +A++ + +F A+ +LG + G
Sbjct: 148 SALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEI 207
Query: 334 EAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQ----- 388
A F+KA+ L+ N + G +L A+ + R L L P + V
Sbjct: 208 WLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLAC 267
Query: 389 --YMKGLSHVAMGQFYEGIKAQ 408
Y +GL +A+ + I+ Q
Sbjct: 268 VYYEQGLIDLAIDTYRRAIELQ 289
Score = 33.9 bits (76), Expect = 0.66
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 5/99 (5%)
Query: 149 IAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRV 208
+A VL G EA+ H+ ++ P A G L ++++ + AL +R
Sbjct: 367 LASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMG-----NTLKEMQDVQGALQCYTRA 421
Query: 209 ITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQP 247
I + P + A I G I EA+ A++L+P
Sbjct: 422 IQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 460
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 68.9 bits (167), Expect = 2e-11
Identities = 56/241 (23%), Positives = 99/241 (41%), Gaps = 7/241 (2%)
Query: 147 LAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELS 206
++ Y L G + +A HF+ + +P A GR + + G N A+ +++
Sbjct: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMG-----NNFAAMQDIN 1433
Query: 207 RVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARL-YRHRGTLYFISEDY 265
+ + E R I +G A+ D AI L P L Y + G +YF +
Sbjct: 1434 AAMKISTTA-EFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQF 1492
Query: 266 ATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQ 325
+ A + F ++L+ + ++ + +T +EA E F ++ + Y +
Sbjct: 1493 SQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAH 1552
Query: 326 AYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNE 385
Y L +E A E KAL L N R + G ++EA+ ++ + L LE Y
Sbjct: 1553 FYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYAS 1612
Query: 386 V 386
V
Sbjct: 1613 V 1613
Score = 67.4 bits (163), Expect = 5e-11
Identities = 55/234 (23%), Positives = 105/234 (44%), Gaps = 8/234 (3%)
Query: 180 IYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDL 239
+Y G+ Y ++G + +LA+ +L+ I+++ + F RA + + + A+ D
Sbjct: 1198 LYNLGLCYMEEGNLQM-TYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQMALTDY 1256
Query: 240 TKAIQLQPSARL----YRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFH 295
+ L + + + +RG +Y Y A EDF+Q+ +++ +
Sbjct: 1257 GIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHR 1316
Query: 296 RGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEA---ATESFQKALLLNQNHVQ 352
+EA+ F ALK F+DAY G +Y E G+ EA A + F KAL +N +++
Sbjct: 1317 INEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIK 1376
Query: 353 TLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIK 406
G L G Q+A +F + +P N + + + + MG + ++
Sbjct: 1377 ARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQ 1430
Score = 62.0 bits (149), Expect = 2e-09
Identities = 51/205 (24%), Positives = 90/205 (43%), Gaps = 4/205 (1%)
Query: 221 QRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQSLELN 279
+R I LG++ A+NDL + I L+P Y HR +Y + A +D + N
Sbjct: 922 RRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYN 981
Query: 280 KNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATES 339
KN A L K + + + AI ++ +A+K D Y G+ Y E+ N A +
Sbjct: 982 KNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMY-EITNKVLAIDD 1040
Query: 340 FQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVC--QYMKGLSHVA 397
F K + + L RG+ + + A+++F L ++ N QY+ + +
Sbjct: 1041 FSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYD 1100
Query: 398 MGQFYEGIKAQTKVMLNDPLPGQKA 422
+ +F A+ L++ P Q+A
Sbjct: 1101 LAKFTIYQIAEMDKGLSELSPMQQA 1125
Score = 48.5 bits (114), Expect = 3e-05
Identities = 70/299 (23%), Positives = 115/299 (38%), Gaps = 47/299 (15%)
Query: 159 YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRP-- 216
Y AI +T + + + A Y R + Y K I+ ++AL + V+ L+
Sbjct: 1215 YKLAITDLTTAISMDKNSYIAFYNRALCYTK-----IRELQMALTDYGIVLLLDATETVK 1269
Query: 217 ---------------------EVFEQRAEILSPLG-----------RINE---AVNDLTK 241
E F+Q A I G RINE AVN T
Sbjct: 1270 LNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTW 1329
Query: 242 AIQLQPS-ARLYRHRGTLYF-ISEDYAT--AHEDFQQSLELNKNQPIAMLYKGLTFFHRG 297
A+++ P Y RG Y D AT A +DF ++L +N A + G +G
Sbjct: 1330 ALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQG 1389
Query: 298 LLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLR 357
++A F A+ AY+ ++GN AA + A+ ++ + L R
Sbjct: 1390 KFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNR 1448
Query: 358 GMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 416
G++ G Q A+K+++ + L P + + G + QF + +K + DP
Sbjct: 1449 GVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDP 1507
Score = 47.4 bits (111), Expect = 6e-05
Identities = 55/245 (22%), Positives = 99/245 (40%), Gaps = 18/245 (7%)
Query: 211 LEPDRPE----VFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYA 266
+E D P+ +E +IL+ E +ND TK A Y RG +Y
Sbjct: 886 VESDLPQEVIKYYESEVKILT------EEINDKTKY-----PAFAYCRRGAIYRKLGKLQ 934
Query: 267 TAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQA 326
+A D Q+ + L A ++ L + + + EA++ K + +AY S +
Sbjct: 935 SAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEI 994
Query: 327 YRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEV 386
YR + A ++ +A+ RG M Y + A+ +F +C+ +P
Sbjct: 995 YRGKKDITLAILNYTQAIKSTPTDADIYFRRGEM-YEITNKVLAIDDFSKCIFYDPKRTD 1053
Query: 387 CQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKY--LREYSRYLHAHLD 444
+GL + ++ I+ T ++ D Q L +KY L +++ Y A +D
Sbjct: 1054 ALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMD 1113
Query: 445 TPLTE 449
L+E
Sbjct: 1114 KGLSE 1118
Score = 43.5 bits (101), Expect = 8e-04
Identities = 47/246 (19%), Positives = 95/246 (38%), Gaps = 38/246 (15%)
Query: 159 YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEV 218
++EA+ F+ L+ P + A GRG +Y + G HD + + A + + + + P +
Sbjct: 1320 FEEAVNFFTWALKINPCFLDAYVGRGNSYMEYG-HD-EATKQAQKDFLKALHINPAYIKA 1377
Query: 219 FEQRAEILSPLGRINEAVNDLTKAIQLQPSARL-YRHRGTLYFISEDYATAHEDFQQSLE 277
L G+ +A N T AI P L Y R + + A +D +++
Sbjct: 1378 RISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMK 1437
Query: 278 LNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAAT 337
++ +RG++ E +G+ + A
Sbjct: 1438 ISTTAEFLT--------NRGVIHEF---------------------------MGHKQNAM 1462
Query: 338 ESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVA 397
+ +Q A+ LN + G + +HH +A F + L+ +P NE + +++
Sbjct: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522
Query: 398 MGQFYE 403
+ ++ E
Sbjct: 1523 LKKYEE 1528
>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 68.9 bits (167), Expect = 2e-11
Identities = 56/241 (23%), Positives = 99/241 (41%), Gaps = 7/241 (2%)
Query: 147 LAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELS 206
++ Y L G + +A HF+ + +P A GR + + G N A+ +++
Sbjct: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMG-----NNFAAMQDIN 1433
Query: 207 RVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARL-YRHRGTLYFISEDY 265
+ + E R I +G A+ D AI L P L Y + G +YF +
Sbjct: 1434 AAMKISTTA-EFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQF 1492
Query: 266 ATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQ 325
+ A + F ++L+ + ++ + +T +EA E F ++ + Y +
Sbjct: 1493 SQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAH 1552
Query: 326 AYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNE 385
Y L +E A E KAL L N R + G ++EA+ ++ + L LE Y
Sbjct: 1553 FYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYAS 1612
Query: 386 V 386
V
Sbjct: 1613 V 1613
Score = 67.4 bits (163), Expect = 5e-11
Identities = 55/234 (23%), Positives = 105/234 (44%), Gaps = 8/234 (3%)
Query: 180 IYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDL 239
+Y G+ Y ++G + +LA+ +L+ I+++ + F RA + + + A+ D
Sbjct: 1198 LYNLGLCYMEEGNLQM-TYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQMALTDY 1256
Query: 240 TKAIQLQPSARL----YRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFH 295
+ L + + + +RG +Y Y A EDF+Q+ +++ +
Sbjct: 1257 GIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHR 1316
Query: 296 RGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEA---ATESFQKALLLNQNHVQ 352
+EA+ F ALK F+DAY G +Y E G+ EA A + F KAL +N +++
Sbjct: 1317 INEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIK 1376
Query: 353 TLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIK 406
G L G Q+A +F + +P N + + + + MG + ++
Sbjct: 1377 ARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQ 1430
Score = 62.0 bits (149), Expect = 2e-09
Identities = 51/205 (24%), Positives = 90/205 (43%), Gaps = 4/205 (1%)
Query: 221 QRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQSLELN 279
+R I LG++ A+NDL + I L+P Y HR +Y + A +D + N
Sbjct: 922 RRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYN 981
Query: 280 KNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATES 339
KN A L K + + + AI ++ +A+K D Y G+ Y E+ N A +
Sbjct: 982 KNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMY-EITNKVLAIDD 1040
Query: 340 FQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVC--QYMKGLSHVA 397
F K + + L RG+ + + A+++F L ++ N QY+ + +
Sbjct: 1041 FSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYD 1100
Query: 398 MGQFYEGIKAQTKVMLNDPLPGQKA 422
+ +F A+ L++ P Q+A
Sbjct: 1101 LAKFTIYQIAEMDKGLSELSPMQQA 1125
Score = 48.5 bits (114), Expect = 3e-05
Identities = 70/299 (23%), Positives = 115/299 (38%), Gaps = 47/299 (15%)
Query: 159 YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRP-- 216
Y AI +T + + + A Y R + Y K I+ ++AL + V+ L+
Sbjct: 1215 YKLAITDLTTAISMDKNSYIAFYNRALCYTK-----IRELQMALTDYGIVLLLDATETVK 1269
Query: 217 ---------------------EVFEQRAEILSPLG-----------RINE---AVNDLTK 241
E F+Q A I G RINE AVN T
Sbjct: 1270 LNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTW 1329
Query: 242 AIQLQPS-ARLYRHRGTLYF-ISEDYAT--AHEDFQQSLELNKNQPIAMLYKGLTFFHRG 297
A+++ P Y RG Y D AT A +DF ++L +N A + G +G
Sbjct: 1330 ALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQG 1389
Query: 298 LLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLR 357
++A F A+ AY+ ++GN AA + A+ ++ + L R
Sbjct: 1390 KFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNR 1448
Query: 358 GMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 416
G++ G Q A+K+++ + L P + + G + QF + +K + DP
Sbjct: 1449 GVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDP 1507
Score = 47.4 bits (111), Expect = 6e-05
Identities = 55/245 (22%), Positives = 99/245 (40%), Gaps = 18/245 (7%)
Query: 211 LEPDRPE----VFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYA 266
+E D P+ +E +IL+ E +ND TK A Y RG +Y
Sbjct: 886 VESDLPQEVIKYYESEVKILT------EEINDKTKY-----PAFAYCRRGAIYRKLGKLQ 934
Query: 267 TAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQA 326
+A D Q+ + L A ++ L + + + EA++ K + +AY S +
Sbjct: 935 SAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEI 994
Query: 327 YRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEV 386
YR + A ++ +A+ RG M Y + A+ +F +C+ +P
Sbjct: 995 YRGKKDITLAILNYTQAIKSTPTDADIYFRRGEM-YEITNKVLAIDDFSKCIFYDPKRTD 1053
Query: 387 CQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKY--LREYSRYLHAHLD 444
+GL + ++ I+ T ++ D Q L +KY L +++ Y A +D
Sbjct: 1054 ALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMD 1113
Query: 445 TPLTE 449
L+E
Sbjct: 1114 KGLSE 1118
Score = 43.5 bits (101), Expect = 8e-04
Identities = 47/246 (19%), Positives = 95/246 (38%), Gaps = 38/246 (15%)
Query: 159 YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEV 218
++EA+ F+ L+ P + A GRG +Y + G HD + + A + + + + P +
Sbjct: 1320 FEEAVNFFTWALKINPCFLDAYVGRGNSYMEYG-HD-EATKQAQKDFLKALHINPAYIKA 1377
Query: 219 FEQRAEILSPLGRINEAVNDLTKAIQLQPSARL-YRHRGTLYFISEDYATAHEDFQQSLE 277
L G+ +A N T AI P L Y R + + A +D +++
Sbjct: 1378 RISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMK 1437
Query: 278 LNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAAT 337
++ +RG++ E +G+ + A
Sbjct: 1438 ISTTAEFLT--------NRGVIHEF---------------------------MGHKQNAM 1462
Query: 338 ESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVA 397
+ +Q A+ LN + G + +HH +A F + L+ +P NE + +++
Sbjct: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522
Query: 398 MGQFYE 403
+ ++ E
Sbjct: 1523 LKKYEE 1528
>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
sapiens]
Length = 1614
Score = 68.9 bits (167), Expect = 2e-11
Identities = 56/241 (23%), Positives = 99/241 (41%), Gaps = 7/241 (2%)
Query: 147 LAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELS 206
++ Y L G + +A HF+ + +P A GR + + G N A+ +++
Sbjct: 1379 ISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMG-----NNFAAMQDIN 1433
Query: 207 RVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARL-YRHRGTLYFISEDY 265
+ + E R I +G A+ D AI L P L Y + G +YF +
Sbjct: 1434 AAMKISTTA-EFLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQF 1492
Query: 266 ATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQ 325
+ A + F ++L+ + ++ + +T +EA E F ++ + Y +
Sbjct: 1493 SQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAH 1552
Query: 326 AYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNE 385
Y L +E A E KAL L N R + G ++EA+ ++ + L LE Y
Sbjct: 1553 FYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLEDYAS 1612
Query: 386 V 386
V
Sbjct: 1613 V 1613
Score = 68.2 bits (165), Expect = 3e-11
Identities = 55/234 (23%), Positives = 105/234 (44%), Gaps = 8/234 (3%)
Query: 180 IYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDL 239
+Y G+ Y ++G + +LA+ +L+ I+++ + F RA + + + A+ D
Sbjct: 1198 LYNLGLCYMEEGNLQM-TYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDY 1256
Query: 240 TKAIQLQPSARL----YRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFH 295
+ L + + + +RG +Y Y A EDF+Q+ +++ +
Sbjct: 1257 GIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHR 1316
Query: 296 RGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEA---ATESFQKALLLNQNHVQ 352
+EA+ F ALK F+DAY G +Y E G+ EA A + F KAL +N +++
Sbjct: 1317 INEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIK 1376
Query: 353 TLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIK 406
G L G Q+A +F + +P N + + + + MG + ++
Sbjct: 1377 ARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQ 1430
Score = 62.0 bits (149), Expect = 2e-09
Identities = 51/205 (24%), Positives = 90/205 (43%), Gaps = 4/205 (1%)
Query: 221 QRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQSLELN 279
+R I LG++ A+NDL + I L+P Y HR +Y + A +D + N
Sbjct: 922 RRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYN 981
Query: 280 KNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATES 339
KN A L K + + + AI ++ +A+K D Y G+ Y E+ N A +
Sbjct: 982 KNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMY-EITNKVLAIDD 1040
Query: 340 FQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVC--QYMKGLSHVA 397
F K + + L RG+ + + A+++F L ++ N QY+ + +
Sbjct: 1041 FSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYD 1100
Query: 398 MGQFYEGIKAQTKVMLNDPLPGQKA 422
+ +F A+ L++ P Q+A
Sbjct: 1101 LAKFTIYQIAEMDKGLSELSPMQQA 1125
Score = 49.7 bits (117), Expect = 1e-05
Identities = 70/299 (23%), Positives = 116/299 (38%), Gaps = 47/299 (15%)
Query: 159 YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRP-- 216
Y AI +T + + + +A Y R + Y K I+ ++AL + V+ L+
Sbjct: 1215 YKLAITDLTTAISMDKNSYTAFYNRALCYTK-----IRELQMALTDYGIVLLLDATETVK 1269
Query: 217 ---------------------EVFEQRAEILSPLG-----------RINE---AVNDLTK 241
E F+Q A I G RINE AVN T
Sbjct: 1270 LNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTW 1329
Query: 242 AIQLQPS-ARLYRHRGTLYF-ISEDYAT--AHEDFQQSLELNKNQPIAMLYKGLTFFHRG 297
A+++ P Y RG Y D AT A +DF ++L +N A + G +G
Sbjct: 1330 ALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISFGYNLQAQG 1389
Query: 298 LLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLR 357
++A F A+ AY+ ++GN AA + A+ ++ + L R
Sbjct: 1390 KFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNR 1448
Query: 358 GMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 416
G++ G Q A+K+++ + L P + + G + QF + +K + DP
Sbjct: 1449 GVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDP 1507
Score = 47.4 bits (111), Expect = 6e-05
Identities = 55/245 (22%), Positives = 99/245 (40%), Gaps = 18/245 (7%)
Query: 211 LEPDRPE----VFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYA 266
+E D P+ +E +IL+ E +ND TK A Y RG +Y
Sbjct: 886 VESDLPQEVIKYYESEVKILT------EEINDKTKY-----PAFAYCRRGAIYRKLGKLQ 934
Query: 267 TAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQA 326
+A D Q+ + L A ++ L + + + EA++ K + +AY S +
Sbjct: 935 SAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEI 994
Query: 327 YRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEV 386
YR + A ++ +A+ RG M Y + A+ +F +C+ +P
Sbjct: 995 YRGKKDITLAILNYTQAIKSTPTDADIYFRRGEM-YEITNKVLAIDDFSKCIFYDPKRTD 1053
Query: 387 CQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKY--LREYSRYLHAHLD 444
+GL + ++ I+ T ++ D Q L +KY L +++ Y A +D
Sbjct: 1054 ALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQARGQYLLMMKYYDLAKFTIYQIAEMD 1113
Query: 445 TPLTE 449
L+E
Sbjct: 1114 KGLSE 1118
Score = 43.5 bits (101), Expect = 8e-04
Identities = 47/246 (19%), Positives = 95/246 (38%), Gaps = 38/246 (15%)
Query: 159 YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEV 218
++EA+ F+ L+ P + A GRG +Y + G HD + + A + + + + P +
Sbjct: 1320 FEEAVNFFTWALKINPCFLDAYVGRGNSYMEYG-HD-EATKQAQKDFLKALHINPAYIKA 1377
Query: 219 FEQRAEILSPLGRINEAVNDLTKAIQLQPSARL-YRHRGTLYFISEDYATAHEDFQQSLE 277
L G+ +A N T AI P L Y R + + A +D +++
Sbjct: 1378 RISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMK 1437
Query: 278 LNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAAT 337
++ +RG++ E +G+ + A
Sbjct: 1438 ISTTAEFLT--------NRGVIHEF---------------------------MGHKQNAM 1462
Query: 338 ESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVA 397
+ +Q A+ LN + G + +HH +A F + L+ +P NE + +++
Sbjct: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522
Query: 398 MGQFYE 403
+ ++ E
Sbjct: 1523 LKKYEE 1528
Score = 30.0 bits (66), Expect = 9.6
Identities = 28/134 (20%), Positives = 52/134 (38%), Gaps = 7/134 (5%)
Query: 290 GLTFFHRGLL----KEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALL 345
GL + G L K AI A+ + A+ + Y ++ + A + LL
Sbjct: 1202 GLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLL 1261
Query: 346 LNQNH---VQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFY 402
L+ + T RG++ G AL++FK+ + N + + H + +F
Sbjct: 1262 LDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFE 1321
Query: 403 EGIKAQTKVMLNDP 416
E + T + +P
Sbjct: 1322 EAVNFFTWALKINP 1335
>gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo
sapiens]
Length = 504
Score = 63.5 bits (153), Expect = 8e-10
Identities = 55/227 (24%), Positives = 94/227 (41%), Gaps = 21/227 (9%)
Query: 140 NDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAE 199
N + L + L+ +G +A+ F + +PD A Y R + G ++
Sbjct: 34 NADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMG-----KSK 88
Query: 200 LALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSA---------- 249
AL +L++VI L+ D QR +L G+++EA +D K ++ PS
Sbjct: 89 AALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQL 148
Query: 250 ------RLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAI 303
+ R + F S DY A + LE+ + F G ++AI
Sbjct: 149 IKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAI 208
Query: 304 ESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNH 350
K A K K D +A+ + Y +LG+ E + ++ L L+Q+H
Sbjct: 209 SDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDH 255
Score = 32.7 bits (73), Expect = 1.5
Identities = 20/96 (20%), Positives = 41/96 (42%)
Query: 266 ATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQ 325
A A F +++ + + IA + F G K A+ + ++ K+DF A G
Sbjct: 54 ADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGH 113
Query: 326 AYRELGNFEAATESFQKALLLNQNHVQTLQLRGMML 361
+ G + A + F+K L N + + + + ++
Sbjct: 114 LLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLI 149
Score = 31.2 bits (69), Expect = 4.3
Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 16/92 (17%)
Query: 234 EAVNDLTKAIQLQP-SARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLT 292
EA+ ++ +Q++P + + R Y I E Y A +D++ + E N+N
Sbjct: 324 EAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQ--------- 374
Query: 293 FFHRGLLKEAIESFKEALKQKVDFIDAYKSLG 324
++E +E + LKQ D YK LG
Sbjct: 375 -----QIREGLEKAQRLLKQS-QKRDYYKILG 400
>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
Length = 519
Score = 63.2 bits (152), Expect = 1e-09
Identities = 93/442 (21%), Positives = 168/442 (38%), Gaps = 72/442 (16%)
Query: 128 IAEQKRFPFATDNDSTNEELAIAYVLIGSGL-----------YDEAIRHFSTMLQEEPDL 176
+A + +FP +T++ ++ A + ++ Y+ LQE L
Sbjct: 6 VATRTQFPVSTESQKPRQKKAPEFPILEKQNWLIHLHYIRKDYEACKAVIKEQLQETQGL 65
Query: 177 VS-AIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEA 235
AIY + + + +G +I+ + L LF+ V L P + +Q A L LG+ A
Sbjct: 66 CEYAIYVQALIFRLEG--NIQES-LELFQTCAV--LSPQSADNLKQVARSLFLLGKHKAA 120
Query: 236 VNDLTKAIQL-QPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFF 294
+ +A +L Q + + G Y + + A + +L LN++ + + G
Sbjct: 121 IEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHD-LTYIMLGKIHL 179
Query: 295 HRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTL 354
G L +AIE +K+A++ + + +LG Y +LG ++ A E AL + + + +
Sbjct: 180 LEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAI 239
Query: 355 QLRGMMLYHHGSLQEALKNF----------------------------------KRCLQL 380
G M+ HG AL + KR L
Sbjct: 240 LAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYL 299
Query: 381 EPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKYL-------R 433
P++ Y GL H+ M Q+ + + P G+ + + L R
Sbjct: 300 APFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKR 359
Query: 434 EYSRYLHAHLDTPLTEYNIDVDLPGSFKDHWAKNLPFLIEDYEEQPGLQPHIKDVLHQNF 493
Y+ +H PL N V L + KN + Y+E +KD F
Sbjct: 360 AYAEAVHLDKCNPLVNLNYAVLL---YNQGEKKN---ALAQYQEMEKKVSLLKDNSSLEF 413
Query: 494 ESYKPEVQELICVADRLGSLMQ 515
+S E++ +A +LG+ +Q
Sbjct: 414 DS------EMVEMAQKLGAALQ 429
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 63.2 bits (152), Expect = 1e-09
Identities = 77/341 (22%), Positives = 137/341 (40%), Gaps = 39/341 (11%)
Query: 97 FHDSDCEPKGSSPCDSLL-SLNTEKILSQAKSIAEQKRFPFATDNDSTNEEL---AIAYV 152
FH+++ E + C L S + ++ QA Q AT S++ L + +
Sbjct: 296 FHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQ-----ATQFASSSFVLPFFGLGQM 350
Query: 153 LIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLE 212
I G + A + F +L+ P+ + G Y D + ++A L +V
Sbjct: 351 YIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAAS--EDQEKRDIAKGHLKKVTEQY 408
Query: 213 PDRPEVFEQRAEILSP------LGRINEAVNDLTKAIQLQPSARLYRHRGTLYF------ 260
PD E + + A+IL L A L + +Q + + G L+F
Sbjct: 409 PDDVEAWIELAQILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLG 468
Query: 261 -------ISEDYATAH----EDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEA 309
S D A A E + ++ + + +A LY+ + FH EA + +K
Sbjct: 469 EAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFH-----EAEKLYKNI 523
Query: 310 LKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQE 369
L++ +++D Y LG R+ GNF A++ F++AL +NQ+H L G +
Sbjct: 524 LREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGP 583
Query: 370 ALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTK 410
K F+R L+ M L +V + ++ + + K
Sbjct: 584 GQKKFERILKQPSTQSDTYSMLALGNVWLQTLHQPTRDREK 624
Score = 35.0 bits (79), Expect = 0.30
Identities = 22/102 (21%), Positives = 41/102 (40%), Gaps = 2/102 (1%)
Query: 290 GLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQN 349
G H+G +EA + F + + D D + +L Y E + +A + ++ L
Sbjct: 654 GAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYK 713
Query: 350 HVQT--LQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQY 389
H T + L+ G LQE + + + P + V +
Sbjct: 714 HQNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSDTVLMF 755
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 61.2 bits (147), Expect = 4e-09
Identities = 101/452 (22%), Positives = 179/452 (39%), Gaps = 72/452 (15%)
Query: 213 PDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHED 271
P +V A L GR EA+ A++L P A + GTL + D A A
Sbjct: 372 PHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TRDTAEAKMY 428
Query: 272 FQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELG 331
+Q++L+L+ A+ G + +EAI K+++K +F DAY SL E
Sbjct: 429 YQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQE 488
Query: 332 NFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMK 391
F+ A E +Q + + G+ L G ++A+ ++++ ++L P + V
Sbjct: 489 RFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAM--- 545
Query: 392 GLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKYLREYSRYLH-AHLDTPLTEY 450
V +G+ Y + G+ + E Y R L AH L+
Sbjct: 546 ----VNLGRLYRSL-------------GENSMAE-------EWYKRALQVAHKAEILSPL 581
Query: 451 NIDVDLPGSFKDHWAKNLPFLIEDYEEQPGLQPH-------IKDVLHQNFESYKPEVQEL 503
G +++ ++ Y+E LQP + VL ++ + E
Sbjct: 582 GALYYNTGRYEE--------ALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTN 633
Query: 504 ICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVQRTWTNSKVRMN---GKTRLM 560
V++ G L Y + +K+ + L A++ +A+Q + KV K +
Sbjct: 634 HIVSEETGCLECYRLLSAIYSKQENHDKALDAID--KALQLKPKDPKVISELFFTKGNQL 691
Query: 561 QWRDMFDIAVKWRRIA---DPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYF 617
+ +++ D A + R+A +PDQ W++ I I+G+ ++ R Y+
Sbjct: 692 REQNLLDKAFESYRVAVQLNPDQAQAWMNM-----------GGIQHIKGKYVSAR--AYY 738
Query: 618 EKILHFIKDRILVYHGANN----PKGLLEVRE 645
E+ L + D L+ K L EVRE
Sbjct: 739 ERALQLVPDSKLLKENLAKLDRLEKRLQEVRE 770
Score = 60.1 bits (144), Expect = 9e-09
Identities = 61/264 (23%), Positives = 104/264 (39%), Gaps = 10/264 (3%)
Query: 150 AYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVI 209
A L G EAI H+ T L+ P SA+ G ++ A R +
Sbjct: 382 ANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL--------TRDTAEAKMYYQRAL 433
Query: 210 TLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATA 268
L P +L + EA+ L +I+ P A Y +L E + A
Sbjct: 434 QLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEA 493
Query: 269 HEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYR 328
E +Q ++ + G+ GL ++A+ +++A+K A +LG+ YR
Sbjct: 494 EEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYR 553
Query: 329 ELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQ 388
LG A E +++AL + + + L G + Y+ G +EAL+ ++ L+P +
Sbjct: 554 SLGENSMAEEWYKRALQV-AHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELR 612
Query: 389 YMKGLSHVAMGQFYEGIKAQTKVM 412
MGQ E K ++
Sbjct: 613 LALAQVLAVMGQTKEAEKMTNHIV 636
Score = 55.8 bits (133), Expect = 2e-07
Identities = 58/268 (21%), Positives = 103/268 (38%), Gaps = 15/268 (5%)
Query: 139 DNDSTNEELAIAYVLIGSGL-----YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH 193
D+ E A AY + S L + EA + T ++ PD G+ GL
Sbjct: 465 DSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGL- 523
Query: 194 DIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYR 253
E A+ + I L P + LG + A +A+Q+ A +
Sbjct: 524 ----PEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILS 579
Query: 254 HRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQK 313
G LY+ + Y A + +Q++ L +Q L G KEA + + ++
Sbjct: 580 PLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEE 639
Query: 314 VDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQ----LRGMMLYHHGSLQE 369
++ Y+ L Y + N + A ++ KAL L + + +G L L +
Sbjct: 640 TGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDK 699
Query: 370 ALKNFKRCLQLEP-YNEVCQYMKGLSHV 396
A ++++ +QL P + M G+ H+
Sbjct: 700 AFESYRVAVQLNPDQAQAWMNMGGIQHI 727
>gi|195963398 suppressor of G2 allele of SKP1 isoform a [Homo
sapiens]
Length = 365
Score = 57.0 bits (136), Expect = 7e-08
Identities = 35/97 (36%), Positives = 54/97 (55%), Gaps = 3/97 (3%)
Query: 235 AVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTF 293
A+ +LTKA++ +P A+ Y R + + +Y A D ++SLELN N AML KG+
Sbjct: 30 ALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICE 89
Query: 294 FHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYREL 330
+H A+E+F E QK+D + +GQA +L
Sbjct: 90 YHEKNYAAALETFTEG--QKLDIETGFHRVGQAGLQL 124
Score = 40.0 bits (92), Expect = 0.009
Identities = 24/80 (30%), Positives = 39/80 (48%)
Query: 302 AIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMML 361
A+E +AL+QK D Y + LGN+ A +K+L LN N+ + +G+
Sbjct: 30 ALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICE 89
Query: 362 YHHGSLQEALKNFKRCLQLE 381
YH + AL+ F +L+
Sbjct: 90 YHEKNYAAALETFTEGQKLD 109
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 55.1 bits (131), Expect = 3e-07
Identities = 35/113 (30%), Positives = 58/113 (51%)
Query: 230 GRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYK 289
G EAV T++I P+ Y +R +++ +A +D ++ LEL A+L +
Sbjct: 223 GDYEEAVMYYTRSISALPTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRR 282
Query: 290 GLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQK 342
T+ H+ L+EA E + L + D A K+L + R+L N EAA+E+ K
Sbjct: 283 ATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTK 335
Score = 40.0 bits (92), Expect = 0.009
Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 10/94 (10%)
Query: 156 SGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIK--NAELALFELSRVITLEP 213
SG Y+EA+ +++ + P +V AY + +IK N A + +V+ LEP
Sbjct: 222 SGDYEEAVMYYTRSISALPTVV--------AYNNRAQAEIKLQNWNSAFQDCEKVLELEP 273
Query: 214 DRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQP 247
+ +RA ++ EA DL+K + ++P
Sbjct: 274 GNVKALLRRATTYKHQNKLREATEDLSKVLDVEP 307
Score = 38.5 bits (88), Expect = 0.027
Identities = 52/261 (19%), Positives = 97/261 (37%), Gaps = 42/261 (16%)
Query: 198 AELALFELSRVITLEPDRPEV-------FEQRAEILSPLGRINEAVNDLTKAIQLQP-SA 249
AE A + + LEP E+ + RA G + + D +A++L P S
Sbjct: 462 AEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNCSGCIQDCNRALELHPFSM 521
Query: 250 RLYRHRGTLYFISEDYATAHEDFQQSLEL-----------NKNQPIAMLYKGLTFFHR-- 296
+ R Y E Y A+ D++ L++ N+ I M G + +
Sbjct: 522 KPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQLANDSVNRLSRILMELDGPNWREKLS 581
Query: 297 -------GLLKEAIESFKEALKQKVDFIDAYKSLG-------QAYRELGN-------FEA 335
+ +A KE + ++ +++ G +A +E GN ++
Sbjct: 582 PIPAVPASVPLQAWHPAKEMISKQAGDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKD 641
Query: 336 ATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSH 395
A + + L +N R + +EA ++ + LQL N Y + L+H
Sbjct: 642 ALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAH 701
Query: 396 VAMGQFYEGIKAQTKVMLNDP 416
+ + + + KV+L DP
Sbjct: 702 KGLKNYQKSLIDLNKVILLDP 722
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 55.1 bits (131), Expect = 3e-07
Identities = 35/113 (30%), Positives = 58/113 (51%)
Query: 230 GRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYK 289
G EAV T++I P+ Y +R +++ +A +D ++ LEL A+L +
Sbjct: 223 GDYEEAVMYYTRSISALPTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRR 282
Query: 290 GLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQK 342
T+ H+ L+EA E + L + D A K+L + R+L N EAA+E+ K
Sbjct: 283 ATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTK 335
Score = 40.0 bits (92), Expect = 0.009
Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 10/94 (10%)
Query: 156 SGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIK--NAELALFELSRVITLEP 213
SG Y+EA+ +++ + P +V AY + +IK N A + +V+ LEP
Sbjct: 222 SGDYEEAVMYYTRSISALPTVV--------AYNNRAQAEIKLQNWNSAFQDCEKVLELEP 273
Query: 214 DRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQP 247
+ +RA ++ EA DL+K + ++P
Sbjct: 274 GNVKALLRRATTYKHQNKLREATEDLSKVLDVEP 307
Score = 38.5 bits (88), Expect = 0.027
Identities = 52/261 (19%), Positives = 97/261 (37%), Gaps = 42/261 (16%)
Query: 198 AELALFELSRVITLEPDRPEV-------FEQRAEILSPLGRINEAVNDLTKAIQLQP-SA 249
AE A + + LEP E+ + RA G + + D +A++L P S
Sbjct: 462 AEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNCSGCIQDCNRALELHPFSM 521
Query: 250 RLYRHRGTLYFISEDYATAHEDFQQSLEL-----------NKNQPIAMLYKGLTFFHR-- 296
+ R Y E Y A+ D++ L++ N+ I M G + +
Sbjct: 522 KPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQLANDSVNRLSRILMELDGPNWREKLS 581
Query: 297 -------GLLKEAIESFKEALKQKVDFIDAYKSLG-------QAYRELGN-------FEA 335
+ +A KE + ++ +++ G +A +E GN ++
Sbjct: 582 PIPAVPASVPLQAWHPAKEMISKQAGDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKD 641
Query: 336 ATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSH 395
A + + L +N R + +EA ++ + LQL N Y + L+H
Sbjct: 642 ALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAH 701
Query: 396 VAMGQFYEGIKAQTKVMLNDP 416
+ + + + KV+L DP
Sbjct: 702 KGLKNYQKSLIDLNKVILLDP 722
>gi|5730041 suppressor of G2 allele of SKP1 isoform b [Homo sapiens]
Length = 333
Score = 54.3 bits (129), Expect = 5e-07
Identities = 33/86 (38%), Positives = 49/86 (56%), Gaps = 3/86 (3%)
Query: 235 AVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTF 293
A+ +LTKA++ +P A+ Y R + + +Y A D ++SLELN N AML KG+
Sbjct: 30 ALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICE 89
Query: 294 FHRGLLKEAIESFKEALKQKVDFIDA 319
+H A+E+F E QK+D DA
Sbjct: 90 YHEKNYAAALETFTEG--QKLDSADA 113
Score = 40.0 bits (92), Expect = 0.009
Identities = 24/80 (30%), Positives = 39/80 (48%)
Query: 302 AIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMML 361
A+E +AL+QK D Y + LGN+ A +K+L LN N+ + +G+
Sbjct: 30 ALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLRKGICE 89
Query: 362 YHHGSLQEALKNFKRCLQLE 381
YH + AL+ F +L+
Sbjct: 90 YHEKNYAAALETFTEGQKLD 109
Score = 37.4 bits (85), Expect = 0.060
Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 196 KNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQP-SARLYRH 254
++ + AL EL++ + +PD + + QRA LG AV D K+++L P ++
Sbjct: 25 EDPQAALEELTKALEQKPDDAQYYCQRAYCHILLGNYCVAVADAKKSLELNPNNSTAMLR 84
Query: 255 RGTLYFISEDYATAHEDFQQSLELN 279
+G + ++YA A E F + +L+
Sbjct: 85 KGICEYHEKNYAAALETFTEGQKLD 109
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
sapiens]
Length = 830
Score = 54.3 bits (129), Expect = 5e-07
Identities = 57/251 (22%), Positives = 104/251 (41%), Gaps = 18/251 (7%)
Query: 146 ELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFEL 205
E+ Y+ + S EAI S + + + G AY + L + AE E+
Sbjct: 474 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFE--LSEYMQAERIFSEV 531
Query: 206 SRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDY 265
R+ + E++ L ++ DLT + P A + G + + ++
Sbjct: 532 RRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEA--WCAAGNCFSLQREH 589
Query: 266 ATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQ 325
A + FQ++++++ N A G F L +A+ F+ A++ +A+ LG
Sbjct: 590 DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGM 649
Query: 326 AYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQ------ 379
Y + F A FQKAL +N ++L H G +Q ALK ++ L
Sbjct: 650 IYYKQEKFSLAEMHFQKALDINPQ-------SSVLLCHIGVVQHALKKSEKALDTLNKAI 702
Query: 380 -LEPYNEVCQY 389
++P N +C++
Sbjct: 703 VIDPKNPLCKF 713
Score = 45.8 bits (107), Expect = 2e-04
Identities = 47/236 (19%), Positives = 99/236 (41%), Gaps = 2/236 (0%)
Query: 199 ELALFELSRVIT-LEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRG 256
++AL LS+ +T ++ + PE + S + A+ +AIQ+ P+ A Y G
Sbjct: 555 DVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG 614
Query: 257 TLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDF 316
+ ++E+ A F+ ++ +N A G+ ++ + A F++AL
Sbjct: 615 HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 674
Query: 317 IDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKR 376
+G L E A ++ KA++++ + R +L+ + + AL+ +
Sbjct: 675 SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEE 734
Query: 377 CLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKYL 432
Q+ P + ++ G + +GQ + + + M DP E + +YL
Sbjct: 735 LKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYL 790
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
Length = 824
Score = 54.3 bits (129), Expect = 5e-07
Identities = 57/251 (22%), Positives = 104/251 (41%), Gaps = 18/251 (7%)
Query: 146 ELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFEL 205
E+ Y+ + S EAI S + + + G AY + L + AE E+
Sbjct: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFE--LSEYMQAERIFSEV 525
Query: 206 SRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDY 265
R+ + E++ L ++ DLT + P A + G + + ++
Sbjct: 526 RRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEA--WCAAGNCFSLQREH 583
Query: 266 ATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQ 325
A + FQ++++++ N A G F L +A+ F+ A++ +A+ LG
Sbjct: 584 DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGM 643
Query: 326 AYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQ------ 379
Y + F A FQKAL +N ++L H G +Q ALK ++ L
Sbjct: 644 IYYKQEKFSLAEMHFQKALDINPQ-------SSVLLCHIGVVQHALKKSEKALDTLNKAI 696
Query: 380 -LEPYNEVCQY 389
++P N +C++
Sbjct: 697 VIDPKNPLCKF 707
Score = 45.8 bits (107), Expect = 2e-04
Identities = 47/236 (19%), Positives = 99/236 (41%), Gaps = 2/236 (0%)
Query: 199 ELALFELSRVIT-LEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRG 256
++AL LS+ +T ++ + PE + S + A+ +AIQ+ P+ A Y G
Sbjct: 549 DVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG 608
Query: 257 TLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDF 316
+ ++E+ A F+ ++ +N A G+ ++ + A F++AL
Sbjct: 609 HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 668
Query: 317 IDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKR 376
+G L E A ++ KA++++ + R +L+ + + AL+ +
Sbjct: 669 SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEE 728
Query: 377 CLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKYL 432
Q+ P + ++ G + +GQ + + + M DP E + +YL
Sbjct: 729 LKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYL 784
>gi|116534937 interferon-induced protein with tetratricopeptide
repeats 1 isoform 2 [Homo sapiens]
Length = 478
Score = 53.1 bits (126), Expect = 1e-06
Identities = 47/176 (26%), Positives = 79/176 (44%), Gaps = 22/176 (12%)
Query: 218 VFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLE 277
VF A+ G +++A+ L KA+Q P++ L H+ L + ++ Q E
Sbjct: 253 VFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQ--------MIQIKE 304
Query: 278 LNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAAT 337
K QP + L +++ AI F+ A+++K F A+ L + Y E GN A
Sbjct: 305 ATKGQPRGQNREKLD----KMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 360
Query: 338 ESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGL 393
E+FQK L + +T+Q + +H+G QE K N + Y+K +
Sbjct: 361 ENFQKLLCMKPVVEETMQ---DIHFHYGRFQEFQKK-------SDVNAIIHYLKAI 406
>gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo
sapiens]
Length = 833
Score = 51.2 bits (121), Expect = 4e-06
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 20/176 (11%)
Query: 204 ELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISE 263
E+++ +T R + + Q EIL L + + V + LY++ +
Sbjct: 427 EINKAVTYL--RQKDYNQAVEILKVLEKKDSRVKSAAAT-----------NLSALYYMGK 473
Query: 264 DYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSL 323
D+A A ++ ++ P A+ KG T F G ++A E +KEAL+ +A ++
Sbjct: 474 DFAQASSYADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNI 533
Query: 324 GQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQ 379
G Y +L + A + F K + +N + +LY ++ E ++N + ++
Sbjct: 534 GLTYEKLNRLDEALDCFLKLHAILRNSAE-------VLYQIANIYELMENPSQAIE 582
>gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo
sapiens]
Length = 824
Score = 51.2 bits (121), Expect = 4e-06
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 20/176 (11%)
Query: 204 ELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISE 263
E+++ +T R + + Q EIL L + + V + LY++ +
Sbjct: 418 EINKAVTYL--RQKDYNQAVEILKVLEKKDSRVKSAAAT-----------NLSALYYMGK 464
Query: 264 DYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSL 323
D+A A ++ ++ P A+ KG T F G ++A E +KEAL+ +A ++
Sbjct: 465 DFAQASSYADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNI 524
Query: 324 GQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQ 379
G Y +L + A + F K + +N + +LY ++ E ++N + ++
Sbjct: 525 GLTYEKLNRLDEALDCFLKLHAILRNSAE-------VLYQIANIYELMENPSQAIE 573
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 50.4 bits (119), Expect = 7e-06
Identities = 54/228 (23%), Positives = 97/228 (42%), Gaps = 31/228 (13%)
Query: 187 YGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQ 246
Y KK ++ N ++ I + P + RA L LGR EA+ D ++++L
Sbjct: 39 YAKKDYNEAYNY------YTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLD 92
Query: 247 PS-ARLYRHRGTLYFISEDYATAHEDFQQSLELN----------KNQPIAMLYKGL--TF 293
S R + G + + A FQ++LEL+ KN M Y+ + T
Sbjct: 93 DSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEYEKIAETD 152
Query: 294 FHRGLLKEAIESFKEALKQKVDFIDA---YKSL-GQAYRELGNFEAATESFQKALLLNQN 349
F + ++ + AL +F A +K L + LG + A L ++
Sbjct: 153 FEKRDFRKVVFCMDRAL----EFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDST 208
Query: 350 HVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNE----VCQYMKGL 393
+ L +RG+ LY+ +++A++ F + L++ P +E C+ K L
Sbjct: 209 NADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKAL 256
Score = 47.8 bits (112), Expect = 4e-05
Identities = 25/107 (23%), Positives = 52/107 (48%)
Query: 249 ARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKE 308
A ++ +G Y+ +DY A+ + +++++ + T G +EA+ ++
Sbjct: 28 AETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQ 87
Query: 309 ALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQ 355
+++ F+ + G+ + LGN AA SFQ+AL L+ + Q Q
Sbjct: 88 SVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQ 134
Score = 38.5 bits (88), Expect = 0.027
Identities = 54/229 (23%), Positives = 97/229 (42%), Gaps = 44/229 (19%)
Query: 120 KILSQAKSIAEQKRFPFATD-------NDSTNEELAIAYVLIGSGLY-----DEAIRHFS 167
KIL +A+ +A R+P A DSTN + A + G LY ++A++ F
Sbjct: 179 KIL-KAECLAMLGRYPEAQSVASDILRMDSTNAD---ALYVRGLCLYYEDCIEKAVQFFV 234
Query: 168 TMLQEEPDLVSAIYGRGIAYGKKGLHDIKNA-------ELALFELSRVITLEPDR----P 216
L+ PD A A K + N +LA + + ++P+
Sbjct: 235 QALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNA 294
Query: 217 EVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQS 275
+++ R + S L ++++A+ D T A++L + + Y R Y +E Y A D+++
Sbjct: 295 KLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKV 354
Query: 276 LELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLG 324
+ K + H+ LLK A +++ ++ D YK LG
Sbjct: 355 YQTEKTKE-----------HKQLLKNAQLELRKSKRK-----DYYKILG 387
Score = 32.7 bits (73), Expect = 1.5
Identities = 30/128 (23%), Positives = 54/128 (42%), Gaps = 17/128 (13%)
Query: 232 INEAVNDLTKAIQLQP-------------SARLYRHRGTLYFISEDYATAHEDFQQSLEL 278
I +AV +A+++ P + + + G F +Y A+E + ++L +
Sbjct: 226 IEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGI 285
Query: 279 NKN--QPIAMLY--KGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFE 334
+ N + A LY +G L +AIE A+K +I AY Q Y + +E
Sbjct: 286 DPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYE 345
Query: 335 AATESFQK 342
A ++K
Sbjct: 346 EAVRDYEK 353
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 49.7 bits (117), Expect = 1e-05
Identities = 45/221 (20%), Positives = 100/221 (45%), Gaps = 14/221 (6%)
Query: 209 ITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQP-SARLYRHRGTLYFISEDYAT 267
I ++ + V +++ G+ +EA++ TK + P + L +R + YF + +A
Sbjct: 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAV 185
Query: 268 AHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAY 327
A D ++ LN++ A +G F L+EA + ++ L+ + + +A L +
Sbjct: 186 AESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKIS 245
Query: 328 RELGNFE-----------AATESFQKALLLNQNHVQTL--QLRGMMLYHHGSLQEALKNF 374
+ L + E +TE +K + QN Q + + RG + G + A++ +
Sbjct: 246 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECY 305
Query: 375 KRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLND 415
R + + N + + ++++ + ++ E K T+ +L D
Sbjct: 306 TRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 346
Score = 47.4 bits (111), Expect = 6e-05
Identities = 31/127 (24%), Positives = 57/127 (44%), Gaps = 10/127 (7%)
Query: 263 EDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKS 322
E + E + + ++ + + + KG +F +G EAI+ + + + D Y
Sbjct: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDA-----DPYNP 167
Query: 323 L-----GQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRC 377
+ AY L F A A+ LN+++ + RG + L+EA K+++R
Sbjct: 168 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 227
Query: 378 LQLEPYN 384
L+LEP N
Sbjct: 228 LELEPNN 234
Score = 30.0 bits (66), Expect = 9.6
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Query: 157 GLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRP 216
G Y+ AI ++ + + R +AY K I+ E A + ++ I L+
Sbjct: 296 GKYERAIECYTRGIAADGANALLPANRAMAYLK-----IQKYEEAEKDCTQAILLDGSYS 350
Query: 217 EVFEQRAEILSPLGRINEAVNDLTKAIQLQP 247
+ F +R + LG++NEA D + L+P
Sbjct: 351 KAFARRGTARTFLGKLNEAKQDFETVLLLEP 381
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 49.7 bits (117), Expect = 1e-05
Identities = 45/221 (20%), Positives = 100/221 (45%), Gaps = 14/221 (6%)
Query: 209 ITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQP-SARLYRHRGTLYFISEDYAT 267
I ++ + V +++ G+ +EA++ TK + P + L +R + YF + +A
Sbjct: 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAV 185
Query: 268 AHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAY 327
A D ++ LN++ A +G F L+EA + ++ L+ + + +A L +
Sbjct: 186 AESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKIS 245
Query: 328 RELGNFE-----------AATESFQKALLLNQNHVQTL--QLRGMMLYHHGSLQEALKNF 374
+ L + E +TE +K + QN Q + + RG + G + A++ +
Sbjct: 246 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECY 305
Query: 375 KRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLND 415
R + + N + + ++++ + ++ E K T+ +L D
Sbjct: 306 TRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 346
Score = 47.4 bits (111), Expect = 6e-05
Identities = 31/127 (24%), Positives = 57/127 (44%), Gaps = 10/127 (7%)
Query: 263 EDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKS 322
E + E + + ++ + + + KG +F +G EAI+ + + + D Y
Sbjct: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDA-----DPYNP 167
Query: 323 L-----GQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRC 377
+ AY L F A A+ LN+++ + RG + L+EA K+++R
Sbjct: 168 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 227
Query: 378 LQLEPYN 384
L+LEP N
Sbjct: 228 LELEPNN 234
Score = 30.0 bits (66), Expect = 9.6
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Query: 157 GLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRP 216
G Y+ AI ++ + + R +AY K I+ E A + ++ I L+
Sbjct: 296 GKYERAIECYTRGIAADGANALLPANRAMAYLK-----IQKYEEAEKDCTQAILLDGSYS 350
Query: 217 EVFEQRAEILSPLGRINEAVNDLTKAIQLQP 247
+ F +R + LG++NEA D + L+P
Sbjct: 351 KAFARRGTARTFLGKLNEAKQDFETVLLLEP 381
>gi|58330892 interferon-induced protein with tetratricopeptide
repeats 1-like [Homo sapiens]
Length = 474
Score = 48.9 bits (115), Expect = 2e-05
Identities = 67/276 (24%), Positives = 107/276 (38%), Gaps = 30/276 (10%)
Query: 119 EKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVS 178
+K+ + K A R+ E A+A G Y+ A F L+ P+
Sbjct: 119 DKVENTCKKFANPSRYRMECPEVDCEEGWALAKC--GGKNYERAKTCFEKALEGNPENPE 176
Query: 179 AIYGRGIAY---GKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGR---- 231
G I K +N +L L R + L PD + A L G+
Sbjct: 177 FNTGYAITVYRLDKFNTASGRNKAFSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEG 236
Query: 232 ---INEAVNDLT-KAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIA-- 285
I EA+ ++ +A Q +A+ YR +G++ E A E S L+ +
Sbjct: 237 EKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYR 296
Query: 286 ----MLYKGLTFFHRG--------LLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNF 333
+ + + RG L++ AI F++ + K F AY L + Y E+G+
Sbjct: 297 AQMIQIKEATNWQPRGQDRETVDRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHH 356
Query: 334 EAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQE 369
A E FQK L + + QL+ + YH+G QE
Sbjct: 357 RKAEEHFQKGLRMK---IFEDQLKQEIHYHYGRFQE 389
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 48.5 bits (114), Expect = 3e-05
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 25/202 (12%)
Query: 213 PDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHED 271
P + RA L LGR EA+ D ++++L S R + G + + A
Sbjct: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
Query: 272 FQQSLELN----------KNQPIAMLYKGL--TFFHRGLLKEAIESFKEALKQKVDFIDA 319
FQ++LEL+ KN M Y+ + T F + ++ + AL +F A
Sbjct: 63 FQRALELDHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRAL----EFAPA 118
Query: 320 ---YKSL-GQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFK 375
+K L + LG + A L ++ + L +RG+ LY+ +++A++ F
Sbjct: 119 CHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFV 178
Query: 376 RCLQLEPYNE----VCQYMKGL 393
+ L++ P +E C+ K L
Sbjct: 179 QALRMAPDHEKACIACRNAKAL 200
Score = 39.7 bits (91), Expect = 0.012
Identities = 55/229 (24%), Positives = 97/229 (42%), Gaps = 44/229 (19%)
Query: 120 KILSQAKSIAEQKRFPFATD-------NDSTNEELAIAYVLIGSGLY-----DEAIRHFS 167
KIL +A+ +A R+P A DSTN + A + G LY ++A++ F
Sbjct: 123 KIL-KAECLAMLGRYPEAQSVASDILRMDSTNAD---ALYVRGLCLYYEDCIEKAVQFFV 178
Query: 168 TMLQEEPDLVSAIYGRGIAYGKKGLHDIKNA-------ELALFELSRVITLEPDR----P 216
L+ PD A A K + N +LA + + ++P+
Sbjct: 179 QALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNA 238
Query: 217 EVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQS 275
+++ R + S L ++++A+ D T A++L + + Y R Y +E Y A D+++
Sbjct: 239 KLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKV 298
Query: 276 LELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLG 324
+ K + H+ LLK A K++ ++ D YK LG
Sbjct: 299 YQTEKTKE-----------HKQLLKNAQLELKKSKRK-----DYYKILG 331
Score = 32.7 bits (73), Expect = 1.5
Identities = 30/128 (23%), Positives = 54/128 (42%), Gaps = 17/128 (13%)
Query: 232 INEAVNDLTKAIQLQP-------------SARLYRHRGTLYFISEDYATAHEDFQQSLEL 278
I +AV +A+++ P + + + G F +Y A+E + ++L +
Sbjct: 170 IEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGI 229
Query: 279 NKN--QPIAMLY--KGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFE 334
+ N + A LY +G L +AIE A+K +I AY Q Y + +E
Sbjct: 230 DPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYE 289
Query: 335 AATESFQK 342
A ++K
Sbjct: 290 EAVRDYEK 297
>gi|224809432 transmembrane and tetratricopeptide repeat containing
3 [Homo sapiens]
Length = 914
Score = 47.4 bits (111), Expect = 6e-05
Identities = 46/201 (22%), Positives = 82/201 (40%), Gaps = 24/201 (11%)
Query: 192 LHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS--- 248
L + KN E AL + ++PD L R EA A L P
Sbjct: 456 LENEKNFERALKYFLQATHVQPDDIGAHMNVGRTYKNLNRTKEAEESYMMAKSLMPQIIP 515
Query: 249 ARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKE 308
+ Y R I+ ++ + + + N+++ L+EA + +++
Sbjct: 516 GKKYAAR-----IAPNHLNVYINLANLIRANESR----------------LEEADQLYRQ 554
Query: 309 ALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQ 368
A+ + DF AY S G+ ++ A E++ KAL L++N+ ++
Sbjct: 555 AISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVHIELKEPN 614
Query: 369 EALKNFKRCLQLEPYNEVCQY 389
EALKNF R L+L P +++ +
Sbjct: 615 EALKNFNRALELNPKHKLALF 635
Score = 44.3 bits (103), Expect = 5e-04
Identities = 45/217 (20%), Positives = 93/217 (42%), Gaps = 39/217 (17%)
Query: 207 RVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQL-QPSARLYRHRGTLYFISEDY 265
+ I++ PD + + R E+L + + +A KA++L + +A L+ + ++ ++
Sbjct: 554 QAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVHIELKEP 613
Query: 266 ATAHEDFQQSLELNKNQPIAMLYKGLT------------------------------FFH 295
A ++F ++LELN +A+ + +F+
Sbjct: 614 NEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKRLLSYINEEPLDANGYFN 673
Query: 296 RGLL-------KEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQ 348
G+L EA K+A+K + DF A +L Y + A ++ L
Sbjct: 674 LGMLAMDDKKDNEAEIWMKKAIKLQADFRSALFNLALLYSQTAKELKALPILEELLRYYP 733
Query: 349 NHVQTLQLRG-MMLYHHGSLQEALKNFKRCLQLEPYN 384
+H++ L L+G +++ + A K F+R L+++P N
Sbjct: 734 DHIKGLILKGDILMNQKKDILGAKKCFERILEMDPSN 770
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 233 NEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLT 292
N D+ KA QL + G + E+YA A + + Q++EL+ N + +
Sbjct: 76 NSVPEDVGKADQL-------KDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAA 128
Query: 293 FFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLN 347
G +AI+ ++A+ + AY +G A L FE A S+QKAL L+
Sbjct: 129 QSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLD 183
Score = 35.8 bits (81), Expect = 0.17
Identities = 29/143 (20%), Positives = 58/143 (40%)
Query: 294 FHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQT 353
F K + ++ + V D K G + + N+ AA + + +A+ L+ N+
Sbjct: 62 FTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVY 121
Query: 354 LQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVML 413
R G +A+K+ ++ + ++ GL+ A+ +F E + + K +
Sbjct: 122 YCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALD 181
Query: 414 NDPLPGQKASPEYLKVKYLREYS 436
DP S + + LRE S
Sbjct: 182 LDPENDSYKSNLKIAEQKLREVS 204
Score = 31.6 bits (70), Expect = 3.3
Identities = 19/75 (25%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 206 SRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISED 264
++ I L+P+ + RA S LG +A+ D KAI + ++ Y G
Sbjct: 109 TQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNK 168
Query: 265 YATAHEDFQQSLELN 279
+ A +Q++L+L+
Sbjct: 169 FEEAVTSYQKALDLD 183
>gi|56606133 tetratricopeptide repeat domain 32 [Homo sapiens]
Length = 151
Score = 45.1 bits (105), Expect = 3e-04
Identities = 23/77 (29%), Positives = 38/77 (49%)
Query: 249 ARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKE 308
A Y +RG + + D+ A +D+ ++E+ N + +GL + G +A+E FK+
Sbjct: 58 ATAYNNRGQIKYFRVDFYEAMDDYTSAIEVQPNFEVPYYNRGLILYRLGYFDDALEDFKK 117
Query: 309 ALKQKVDFIDAYKSLGQ 325
L F DA SL Q
Sbjct: 118 VLDLNPGFQDATLSLKQ 134
Score = 37.7 bits (86), Expect = 0.046
Identities = 21/68 (30%), Positives = 33/68 (48%)
Query: 315 DFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNF 374
D AY + GQ +F A + + A+ + N RG++LY G +AL++F
Sbjct: 56 DLATAYNNRGQIKYFRVDFYEAMDDYTSAIEVQPNFEVPYYNRGLILYRLGYFDDALEDF 115
Query: 375 KRCLQLEP 382
K+ L L P
Sbjct: 116 KKVLDLNP 123
Score = 31.2 bits (69), Expect = 4.3
Identities = 16/60 (26%), Positives = 31/60 (51%)
Query: 357 RGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 416
RG + Y EA+ ++ ++++P EV Y +GL +G F + ++ KV+ +P
Sbjct: 64 RGQIKYFRVDFYEAMDDYTSAIEVQPNFEVPYYNRGLILYRLGYFDDALEDFKKVLDLNP 123
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 44.7 bits (104), Expect = 4e-04
Identities = 49/222 (22%), Positives = 80/222 (36%), Gaps = 48/222 (21%)
Query: 212 EPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHE 270
+P P + RA L + A +D A+ L S + Y RG F + A +
Sbjct: 4 DPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKK 63
Query: 271 DFQQSLEL-----------------------------------------------NKNQP 283
D+++ LEL NK Q
Sbjct: 64 DYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQA 123
Query: 284 IAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKA 343
I+ +G FF G + AIE + + + AY ++ +E A + +A
Sbjct: 124 ISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQA 183
Query: 344 LLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNE 385
+LL+ ++ + RG G L EA ++F+ L LEP N+
Sbjct: 184 ILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNK 225
Score = 41.6 bits (96), Expect = 0.003
Identities = 36/175 (20%), Positives = 79/175 (45%), Gaps = 13/175 (7%)
Query: 254 HRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQK 313
+R + YF + +A A D ++ LN++ A +G F L+EA + ++ L+ +
Sbjct: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
Query: 314 VDFIDAYKSLGQAYRELGNFE-----------AATESFQKALLLNQNHVQTL--QLRGMM 360
+ +A L + + L + E +TE +K + QN Q + + RG
Sbjct: 73 PNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNG 132
Query: 361 LYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLND 415
+ G + A++ + R + + N + + ++++ + ++ E K T+ +L D
Sbjct: 133 FFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 187
Score = 30.0 bits (66), Expect = 9.6
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Query: 157 GLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRP 216
G Y+ AI ++ + + R +AY K I+ E A + ++ I L+
Sbjct: 137 GKYERAIECYTRGIAADGANALLPANRAMAYLK-----IQKYEEAEKDCTQAILLDGSYS 191
Query: 217 EVFEQRAEILSPLGRINEAVNDLTKAIQLQP 247
+ F +R + LG++NEA D + L+P
Sbjct: 192 KAFARRGTARTFLGKLNEAKQDFETVLLLEP 222
>gi|212549738 anaphase-promoting complex subunit 7 isoform b [Homo
sapiens]
Length = 537
Score = 44.7 bits (104), Expect = 4e-04
Identities = 52/211 (24%), Positives = 99/211 (46%), Gaps = 21/211 (9%)
Query: 150 AYVLIGSGLYDEAIRHF-----STMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFE 204
AY + +G AI ++L++ DL+ ++ Y + G D KN+ L FE
Sbjct: 242 AYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLAD---LYFRAG--DNKNSVLK-FE 295
Query: 205 LSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRGTLYFISE 263
+++ L+P + + +L+ GR+ + N + + A + G F S+
Sbjct: 296 QAQM--LDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSK 353
Query: 264 DYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSL 323
Y+ A ++++LN N A+L KG + G ++EAI F+EA++ +D Y+ L
Sbjct: 354 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGL 413
Query: 324 GQAYRELGNFEAATESFQKALLLNQNHVQTL 354
+ Y A+ S ++A+++ N +TL
Sbjct: 414 IECY-------LASNSIREAMVMANNVYKTL 437
Score = 39.7 bits (91), Expect = 0.012
Identities = 34/114 (29%), Positives = 49/114 (42%), Gaps = 27/114 (23%)
Query: 342 KALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQF 401
KA+ LN N VQ L L+G L + G +QEA+ +F+ ++L P C ++A
Sbjct: 364 KAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSI 423
Query: 402 YE------------GIKAQT-----KVMLNDPLPGQKAS----------PEYLK 428
E G AQT V L DP+ +KA P+Y+K
Sbjct: 424 REAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIK 477
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,826,604
Number of Sequences: 37866
Number of extensions: 1444228
Number of successful extensions: 4846
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 4285
Number of HSP's gapped (non-prelim): 415
length of query: 860
length of database: 18,247,518
effective HSP length: 111
effective length of query: 749
effective length of database: 14,044,392
effective search space: 10519249608
effective search space used: 10519249608
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.