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Search of human proteins with 170784854
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170784854 PTPRF interacting protein, binding protein 2
(liprin beta 2) [Homo sapiens]
(876 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170784854 PTPRF interacting protein, binding protein 2 (lipri... 1753 0.0
gi|29294627 PTPRF interacting protein binding protein 1 isoform ... 693 0.0
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 170 6e-42
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 170 6e-42
gi|157837985 kazrin isoform E [Homo sapiens] 169 1e-41
gi|29294629 PTPRF interacting protein binding protein 1 isoform ... 159 8e-39
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 149 8e-36
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] 148 2e-35
gi|55769554 protein tyrosine phosphatase, receptor type, f polyp... 137 4e-32
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 70 9e-12
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 62 2e-09
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 62 3e-09
gi|81295809 pericentrin [Homo sapiens] 61 5e-09
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 61 5e-09
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 60 9e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 60 9e-09
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 60 9e-09
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 60 9e-09
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 60 9e-09
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 59 2e-08
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 59 2e-08
gi|109134347 NY-REN-58 antigen [Homo sapiens] 59 2e-08
gi|109134355 NY-REN-58 antigen [Homo sapiens] 59 2e-08
gi|21735548 centrosomal protein 2 [Homo sapiens] 59 2e-08
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 59 2e-08
gi|112420968 coiled-coil domain containing 158 [Homo sapiens] 59 3e-08
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 59 3e-08
gi|45439327 periplakin [Homo sapiens] 59 3e-08
gi|156104908 myosin heavy chain 6 [Homo sapiens] 58 3e-08
gi|28416946 myosin 18A isoform a [Homo sapiens] 58 3e-08
>gi|170784854 PTPRF interacting protein, binding protein 2 (liprin
beta 2) [Homo sapiens]
Length = 876
Score = 1753 bits (4539), Expect = 0.0
Identities = 876/876 (100%), Positives = 876/876 (100%)
Query: 1 MASDASHALEAALEQMDGIIAGTKTGADLSDGTCEPGLASPASYMNPFPVLHLIEDLRLA 60
MASDASHALEAALEQMDGIIAGTKTGADLSDGTCEPGLASPASYMNPFPVLHLIEDLRLA
Sbjct: 1 MASDASHALEAALEQMDGIIAGTKTGADLSDGTCEPGLASPASYMNPFPVLHLIEDLRLA 60
Query: 61 LEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKES 120
LEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKES
Sbjct: 61 LEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKES 120
Query: 121 LILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTE 180
LILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTE
Sbjct: 121 LILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTE 180
Query: 181 VSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEV 240
VSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEV
Sbjct: 181 VSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEV 240
Query: 241 AQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRI 300
AQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRI
Sbjct: 241 AQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRI 300
Query: 301 EELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPR 360
EELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPR
Sbjct: 301 EELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPR 360
Query: 361 CSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFLAEH 420
CSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFLAEH
Sbjct: 361 CSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFLAEH 420
Query: 421 KYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLRDTESGWDDTAVVNDLSSTSSG 480
KYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLRDTESGWDDTAVVNDLSSTSSG
Sbjct: 421 KYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLRDTESGWDDTAVVNDLSSTSSG 480
Query: 481 TESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSR 540
TESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSR
Sbjct: 481 TESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSR 540
Query: 541 TRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKE 600
TRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKE
Sbjct: 541 TRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKE 600
Query: 601 LGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDGRM 660
LGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDGRM
Sbjct: 601 LGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDGRM 660
Query: 661 LQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSN 720
LQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSN
Sbjct: 661 LQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSN 720
Query: 721 HRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTK 780
HRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTK
Sbjct: 721 HRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTK 780
Query: 781 FNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPME 840
FNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPME
Sbjct: 781 FNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPME 840
Query: 841 PSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS 876
PSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS
Sbjct: 841 PSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS 876
>gi|29294627 PTPRF interacting protein binding protein 1 isoform 1
[Homo sapiens]
Length = 1005
Score = 693 bits (1789), Expect = 0.0
Identities = 432/977 (44%), Positives = 568/977 (58%), Gaps = 123/977 (12%)
Query: 1 MASDASHALEAALEQMDGIIAGTKTGADLSDGTCEPGLASPAS-YMNPFPVLHLIEDLRL 59
M SDAS L AALEQMDGIIAG+K + S+G + SP S +M LHL+EDLR
Sbjct: 1 MMSDASDMLAAALEQMDGIIAGSKA-LEYSNGIFD--CQSPTSPFMGSLRALHLVEDLRG 57
Query: 60 ALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKE 119
LEM+E E+ L QIP TA + EW + ++ N H + + YQERLARLE DKE
Sbjct: 58 LLEMMET-DEKEGLRCQIPDSTAETLVEWLQSQMT--NGHLPGNGDVYQERLARLENDKE 114
Query: 120 SLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMT 179
SL+LQVSVLTDQVEAQGEKIRDLE CLE H+ K+NA EEMLQQELLSRTSLETQKLDLM
Sbjct: 115 SLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMA 174
Query: 180 EVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATK-- 237
E+S LKLKL +EK++ + E+K R E L+QE+ L++KV E+++ER QYE KLK+TK
Sbjct: 175 EISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDE 234
Query: 238 ------------AEVAQLQEQVALK----------------------DAEIERLHSQLSR 263
+EV +LQE++ K + E++++ +
Sbjct: 235 LASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVES 294
Query: 264 TAALHSESHTERD---QEIQRLKMGMETLLLAN--EDKDRRIEELTGLLNQYRKVKEIVM 318
A + E + + Q + R K +T++LA + KD EEL LN ++
Sbjct: 295 LMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEEL---LNS--SSISSLL 349
Query: 319 VTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPP--------- 369
QG S+ S + G S PEE + + S P++ P
Sbjct: 350 DAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTIL--QVSIPSLLPATVSMETSEK 407
Query: 370 ----PLPQKSLETR--------------AQKKLSCSL------------------EDLRS 393
P P+ S E K L+ SL E ++
Sbjct: 408 SKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQK 467
Query: 394 ESVDKCMDGNQPFPVLEPK---------DSPFLAEHKYPTLPGKLSGATPNGEAAKSPPT 444
S D+ ++PF L P+ D+PF + N A +P
Sbjct: 468 TSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNL 527
Query: 445 ICQPDATGSSLLRLRDTESGWDDTAVVNDLSSTSSGTESGPQS------PLTPDGKRNPK 498
+ A+ +L +TE +TA DL+ SS + ++ P +PD K+ +
Sbjct: 528 DRKRSASAPTLA---ETEK---ETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSR 581
Query: 499 GIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSRTRDSKGQKSDANAPFAQW 558
GI K +GK+RR+QS F D + EF+RGG RATAGPRL +RD SD + PFA+W
Sbjct: 582 GIMKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKW 641
Query: 559 STERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKA 618
+ E+VC WL + GL Y+ + W++SG TLL A+ QD+EKELGIKH LHRKKL LA++A
Sbjct: 642 TKEQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQA 701
Query: 619 INTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQL 678
+ +++E LD WVTRWLDDIGLPQYK QF E RVDGRML Y+TV+DLL LKV S L
Sbjct: 702 LGSEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVL 761
Query: 679 HHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPN 738
HHLSIK AI VL +N F P+CL RRP+DE+ ++PSEV +W+NHRVMEWLRSVDLAEYAPN
Sbjct: 762 HHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPN 821
Query: 739 LRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKREKMA 798
LRGSGVHGGL++LEPRF +T+A LLNIPP KTLLRRHL T FN LIG EA+ +KR+ M
Sbjct: 822 LRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAME 881
Query: 799 SPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPMEPSDGVSDSHRVYSGYRGL 858
P Y LT TAKV+P+KL FS+FGN+RKKK ++ +Y+CPME + + G++
Sbjct: 882 LPDYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASK--KGFKPG 939
Query: 859 SPLDAPELDGLDQVGQI 875
+ E D LD++ Q+
Sbjct: 940 LDMRLYEEDDLDRLEQM 956
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 170 bits (430), Expect = 6e-42
Identities = 206/829 (24%), Positives = 336/829 (40%), Gaps = 110/829 (13%)
Query: 53 LIEDLRLALEMLELPQERAALL------SQIPGPTAAYIKEWFEESLSQ---VNHHSAAS 103
L D+R A+ E +ER L +Q + + + E ++ ++ +
Sbjct: 304 LQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDK 363
Query: 104 NETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGH---QVKLNAAEEML 160
N QERL E + + + L + +++ L E H + +L E L
Sbjct: 364 NRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQL 423
Query: 161 Q---QELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKA-----EELLQEL 212
+ QEL E + +S+ KL+ E+ + K+R A LL+E+
Sbjct: 424 EEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREV 483
Query: 213 RHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALH---S 269
K ++EE +++++Q ++A +AE+ + + L+ A + L +
Sbjct: 484 ESAKKQLEETQHDKDQLVLNIEALRAEL----DHMRLRGASLHHGRPHLGSVPDFRFPMA 539
Query: 270 ESHTERDQEIQRLKMGMETLLLA-----------NEDKDRRIEELTGLLNQYRKVKEIVM 318
+ HT+ L+ + L A NE R ++ + L N + +
Sbjct: 540 DGHTDSYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDAD 599
Query: 319 VTQGPSERTL---SINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKS 375
V+ G +R S++ P G E+L R +
Sbjct: 600 VSDGEDDRDTLLSSVDLLSPSGQADAHTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEE 659
Query: 376 LETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLE-----PKDSPFLAEHKYPTLP---- 426
+E+R +L RS M P+P P S + P P
Sbjct: 660 IESRVGSGSLDNLGRFRS------MSSIPPYPASSLASSSPPGSGRSTPRRIPHSPAREV 713
Query: 427 ---GKLSGATPNGEAAKSPPTICQPDATGSS---LLRLRDTESGWDDTAVVNDLSS--TS 478
G ++ P+ E + T + + + S LRL G T D+ S
Sbjct: 714 DRLGVMTLLPPSREEVRDDKTTIKCETSPPSSPRALRLDRLHKGALHTVSHEDIRDIRNS 773
Query: 479 SGTESGPQS-PLTPDGKRNP-------KGIKKFWGKI-------RRTQSG---------- 513
+G++ GP S P + + ++ KGIK G++ R Q+G
Sbjct: 774 TGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGQTGKEALGQAGVS 833
Query: 514 ---NFYTDTLGMAEFRRGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDF 570
N D LG+++ G +A +L + + + PFAQW V WLE +
Sbjct: 834 ETDNSSQDALGLSKL---GGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELW 890
Query: 571 -GL-AQYVIFARQWVSSGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAI------NTK 622
G+ A YV R V SG + + ++++E+GI +PLHR KL LA++ I +
Sbjct: 891 VGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAP 950
Query: 623 QEEKSAL----LDHIWV-TRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLF-LKVTS 676
++ L ++H W+ WL +GLPQY+ F E VD RML +LT DL LK+
Sbjct: 951 PTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVD 1010
Query: 677 QLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYA 736
H S +C I L ++ L R+ +ES +V+ WSN RV+ W+ S+ L EYA
Sbjct: 1011 SFHRNSFQCGIMCLRRLNYDRKELERK-REESQSEIKDVLVWSNDRVIRWILSIGLKEYA 1069
Query: 737 PNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALI 785
NL SGVHG L+ L+ F LA+LL IP Q T R L +FN L+
Sbjct: 1070 NNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLL 1118
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/277 (19%), Positives = 111/277 (40%), Gaps = 46/277 (16%)
Query: 55 EDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNE---TYQERL 111
EDL +E+ E+ +++ SQ+ +E L+ ++ H E T ++ L
Sbjct: 247 EDLAKVIELQEIISKQSREQSQM------------KERLASLSSHVTELEEDLDTARKDL 294
Query: 112 ARLEGDKESLILQVSVLTDQVEAQGEKIRDLE---VCLEGHQVKLNAAEEMLQQELLSRT 168
+ E L V Q E E+I LE + + ++ + L+ E+ ++
Sbjct: 295 IKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKD 354
Query: 169 SLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQ 228
S+ Q E + R+ +E+ AE+ LQ+ + E+E E Q
Sbjct: 355 SMHRQT-----------------EDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQ 397
Query: 229 YEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALH--SESHTER---------DQ 277
L + ++E++ +A++E + +L R +E H +R +
Sbjct: 398 RVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSE 457
Query: 278 EIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVK 314
+RL++ ++ + A EDK+ + E+ Q + +
Sbjct: 458 SNERLQLHLKERMAALEDKNSLLREVESAKKQLEETQ 494
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sapiens]
Length = 1202
Score = 170 bits (430), Expect = 6e-42
Identities = 206/829 (24%), Positives = 336/829 (40%), Gaps = 110/829 (13%)
Query: 53 LIEDLRLALEMLELPQERAALL------SQIPGPTAAYIKEWFEESLSQ---VNHHSAAS 103
L D+R A+ E +ER L +Q + + + E ++ ++ +
Sbjct: 304 LQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDK 363
Query: 104 NETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGH---QVKLNAAEEML 160
N QERL E + + + L + +++ L E H + +L E L
Sbjct: 364 NRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQL 423
Query: 161 Q---QELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKA-----EELLQEL 212
+ QEL E + +S+ KL+ E+ + K+R A LL+E+
Sbjct: 424 EEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREV 483
Query: 213 RHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALH---S 269
K ++EE +++++Q ++A +AE+ + + L+ A + L +
Sbjct: 484 ESAKKQLEETQHDKDQLVLNIEALRAEL----DHMRLRGASLHHGRPHLGSVPDFRFPMA 539
Query: 270 ESHTERDQEIQRLKMGMETLLLA-----------NEDKDRRIEELTGLLNQYRKVKEIVM 318
+ HT+ L+ + L A NE R ++ + L N + +
Sbjct: 540 DGHTDSYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDAD 599
Query: 319 VTQGPSERTL---SINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKS 375
V+ G +R S++ P G E+L R +
Sbjct: 600 VSDGEDDRDTLLSSVDLLSPSGQADAHTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEE 659
Query: 376 LETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLE-----PKDSPFLAEHKYPTLP---- 426
+E+R +L RS M P+P P S + P P
Sbjct: 660 IESRVGSGSLDNLGRFRS------MSSIPPYPASSLASSSPPGSGRSTPRRIPHSPAREV 713
Query: 427 ---GKLSGATPNGEAAKSPPTICQPDATGSS---LLRLRDTESGWDDTAVVNDLSS--TS 478
G ++ P+ E + T + + + S LRL G T D+ S
Sbjct: 714 DRLGVMTLLPPSREEVRDDKTTIKCETSPPSSPRALRLDRLHKGALHTVSHEDIRDIRNS 773
Query: 479 SGTESGPQS-PLTPDGKRNP-------KGIKKFWGKI-------RRTQSG---------- 513
+G++ GP S P + + ++ KGIK G++ R Q+G
Sbjct: 774 TGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGQTGKEALGQAGVS 833
Query: 514 ---NFYTDTLGMAEFRRGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDF 570
N D LG+++ G +A +L + + + PFAQW V WLE +
Sbjct: 834 ETDNSSQDALGLSKL---GGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELW 890
Query: 571 -GL-AQYVIFARQWVSSGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAI------NTK 622
G+ A YV R V SG + + ++++E+GI +PLHR KL LA++ I +
Sbjct: 891 VGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAP 950
Query: 623 QEEKSAL----LDHIWV-TRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLF-LKVTS 676
++ L ++H W+ WL +GLPQY+ F E VD RML +LT DL LK+
Sbjct: 951 PTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVD 1010
Query: 677 QLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYA 736
H S +C I L ++ L R+ +ES +V+ WSN RV+ W+ S+ L EYA
Sbjct: 1011 SFHRNSFQCGIMCLRRLNYDRKELERK-REESQSEIKDVLVWSNDRVIRWILSIGLKEYA 1069
Query: 737 PNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALI 785
NL SGVHG L+ L+ F LA+LL IP Q T R L +FN L+
Sbjct: 1070 NNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLL 1118
Score = 42.7 bits (99), Expect = 0.001
Identities = 54/277 (19%), Positives = 111/277 (40%), Gaps = 46/277 (16%)
Query: 55 EDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNE---TYQERL 111
EDL +E+ E+ +++ SQ+ +E L+ ++ H E T ++ L
Sbjct: 247 EDLAKVIELQEIISKQSREQSQM------------KERLASLSSHVTELEEDLDTARKDL 294
Query: 112 ARLEGDKESLILQVSVLTDQVEAQGEKIRDLE---VCLEGHQVKLNAAEEMLQQELLSRT 168
+ E L V Q E E+I LE + + ++ + L+ E+ ++
Sbjct: 295 IKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKD 354
Query: 169 SLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQ 228
S+ Q E + R+ +E+ AE+ LQ+ + E+E E Q
Sbjct: 355 SMHRQT-----------------EDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQ 397
Query: 229 YEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALH--SESHTER---------DQ 277
L + ++E++ +A++E + +L R +E H +R +
Sbjct: 398 RVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSE 457
Query: 278 EIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVK 314
+RL++ ++ + A EDK+ + E+ Q + +
Sbjct: 458 SNERLQLHLKERMAALEDKNSLLREVESAKKQLEETQ 494
>gi|157837985 kazrin isoform E [Homo sapiens]
Length = 775
Score = 169 bits (427), Expect = 1e-41
Identities = 174/620 (28%), Positives = 257/620 (41%), Gaps = 70/620 (11%)
Query: 237 KAEVAQLQEQVALKDAEIERLHSQLSRTAALHS-------ESHTERDQEIQRLKMGMETL 289
+ EV++LQE+V L E L L + S E + Q+ Q L E L
Sbjct: 79 REEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEAL 138
Query: 290 LLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSE---RTLSINEEEPEGGFSKWNATN 346
D+ R E T L++Q +++ + + R + +E E K A
Sbjct: 139 QAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAV-KALAKE 197
Query: 347 KDPEELFKQEMPPRCSSPTVGPPPL-PQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQP 405
KD E K E+ + T L Q L+ K+L L + D +
Sbjct: 198 KDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKR 257
Query: 406 FPVLEPKDSPFLAEHKYPT---LPGKLSGATPNGEAA---KSPPTICQPDATGSSLLRLR 459
+ P ++ ++ LP L+ A + PP A S R
Sbjct: 258 HSLAMPGETVLNGNQEWVVQADLP--LTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSR 315
Query: 460 DTESGWDDTAVVNDLSSTSS--------------GTESGP-----QSPLTP------DGK 494
D +A D SST S G GP +P+ D K
Sbjct: 316 QPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIVQSLEDLEDQK 375
Query: 495 RNPKGIKKFWGKI---------RRTQSGNFYTDTLGMAEFRRGGLRATAGP-RLSRTRDS 544
R K K +G I R++ + D+ R L + G ++ R +
Sbjct: 376 RKKKKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCSPTRQSLSLSEGEEQMDRLQQV 435
Query: 545 KGQKSDANAPFAQWSTERVCAWLED-FGLAQYVIFARQWVSSGHTLLTATPQDMEKELGI 603
+ ++ P + W V AWLE + YV + V SG LL+ + +D++ LG+
Sbjct: 436 ELVRT---TPMSHWKAGTVQAWLEVVMAMPMYVKACTENVKSGKVLLSLSDEDLQLGLGV 492
Query: 604 KHPLHRKKLVLAVKAINTKQE----EKSALLDHIWVTR-WLDDIGLPQYKDQFHESRVDG 658
LHR+KL LA++ + K+A LDH WV + WL+DIGL QY F VDG
Sbjct: 493 CSSLHRRKLRLAIEDYRDAEAGRSLSKAAELDHHWVAKAWLNDIGLSQYSQAFQNHLVDG 552
Query: 659 RMLQYLTVNDL-LFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPA--DESNLSPSEV 715
RML L DL L V+ + H +SI I +L+ F+ L R A + N+ P
Sbjct: 553 RMLNSLMKRDLEKHLNVSKKFHQVSILLGIELLYQVNFSREALQERRARCETQNIDP--- 609
Query: 716 VQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRR 775
V W+N RV++W+R +DL EYA NL SGVHG +++LEP F + +A L IP K +LRR
Sbjct: 610 VVWTNQRVLKWVRDIDLKEYADNLTNSGVHGAVLVLEPTFNAEAMATALGIPSGKHILRR 669
Query: 776 HLTTKFNALIGPEAEQEKRE 795
HL + +A+ P RE
Sbjct: 670 HLAEEMSAVFHPANSTGIRE 689
Score = 54.7 bits (130), Expect = 4e-07
Identities = 123/585 (21%), Positives = 214/585 (36%), Gaps = 68/585 (11%)
Query: 127 VLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKL 186
+L ++V E++ L E L ++ E+LS T L Q E++ K
Sbjct: 77 LLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKE 136
Query: 187 KLVGMEKEQREQE-EKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQE 245
L M+ +++ + EK ++ Q L+ + E+L + YE K ++ V L +
Sbjct: 137 ALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAK 196
Query: 246 QVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTG 305
+ L + E L Q + ++ D + R+K L +A + L
Sbjct: 197 EKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAMAK-------QSLAT 249
Query: 306 LLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCS--- 362
L K + M P E L+ N+E A + ++ PP +
Sbjct: 250 LTKDVPKRHSLAM----PGETVLNGNQEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQ 305
Query: 363 SPTVGPPPLPQKSL---ETRAQKKLSCSLEDLRS--ESVDKCMDGNQPFPVLEPKDSPFL 417
+ V P Q S+ + A+ S + D+ S +G+ P PV + +P +
Sbjct: 306 AVRVSPCHSRQPSVISDASAAEGDRSSTPSDINSPRHRTHSLCNGDSPGPVQKNLHNPIV 365
Query: 418 -----------AEHKYPTLPGKLSGATPNGEAAKS--PPTICQPDATGS---SLLRLRDT 461
+ K G +S G+ KS P D+ S L L +
Sbjct: 366 QSLEDLEDQKRKKKKEKMGFGSISRVFARGKQRKSLDPGLFDDSDSQCSPTRQSLSLSEG 425
Query: 462 ESGWDDTAVVNDLSST-SSGTESGPQSPLTPDGKRNPKGIKKFW-----GKIRRTQSGNF 515
E D V + +T S ++G P +K GK+ + S
Sbjct: 426 EEQMDRLQQVELVRTTPMSHWKAGTVQAWLEVVMAMPMYVKACTENVKSGKVLLSLSDED 485
Query: 516 YTDTLGM-AEFRRGGLRATAGPRLSRTRDSKGQKSDANAPFA--QWSTERVCAWLEDFGL 572
LG+ + R LR + RD++ +S + A W + AWL D GL
Sbjct: 486 LQLGLGVCSSLHRRKLRLA----IEDYRDAEAGRSLSKAAELDHHWVAK---AWLNDIGL 538
Query: 573 AQYVIFARQWVSSGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDH 632
+QY + + G L + +D+EK L + H+ ++L ++ + + AL +
Sbjct: 539 SQYSQAFQNHLVDGRMLNSLMKRDLEKHLNVSKKFHQVSILLGIELLYQVNFSREALQER 598
Query: 633 ------------IW----VTRWLDDIGLPQYKDQFHESRVDGRML 661
+W V +W+ DI L +Y D S V G +L
Sbjct: 599 RARCETQNIDPVVWTNQRVLKWVRDIDLKEYADNLTNSGVHGAVL 643
Score = 38.9 bits (89), Expect = 0.021
Identities = 47/214 (21%), Positives = 94/214 (43%), Gaps = 48/214 (22%)
Query: 51 LHLIEDLRLALEML--ELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQ 108
+HL+ ++ EML +L + + S++ T ++ L+Q A + E Q
Sbjct: 89 VHLLRQMK---EMLAKDLEESQGGKSSEVLSATELRVQ------LAQKEQELARAKEALQ 139
Query: 109 ERLA---RLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELL 165
A RL+G+K L+ Q+ L +E++ E++RD E H+ + A + L +E
Sbjct: 140 AMKADRKRLKGEKTDLVSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKE-- 197
Query: 166 SRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENE 225
DL+ +RE+ E +R+A+E L+ +++ +N
Sbjct: 198 ---------KDLL----------------EREKWELRRQAKEATDHATALRSQLDLKDN- 231
Query: 226 RNQYEWKLKATKAEVAQLQEQVALKDAEIERLHS 259
++K +AE+A ++ +A ++ + HS
Sbjct: 232 ------RMKELEAELAMAKQSLATLTKDVPKRHS 259
>gi|29294629 PTPRF interacting protein binding protein 1 isoform 2
[Homo sapiens]
Length = 170
Score = 159 bits (403), Expect = 8e-39
Identities = 95/163 (58%), Positives = 112/163 (68%), Gaps = 7/163 (4%)
Query: 1 MASDASHALEAALEQMDGIIAGTKTGADLSDGTCEPGLASPAS-YMNPFPVLHLIEDLRL 59
M SDAS L AALEQMDGIIAG+K + S+G + SP S +M LHL+EDLR
Sbjct: 1 MMSDASDMLAAALEQMDGIIAGSKA-LEYSNGIFD--CQSPTSPFMGSLRALHLVEDLRG 57
Query: 60 ALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKE 119
LEM+E E+ L QIP TA + EW + ++ N H + + YQERLARLE DKE
Sbjct: 58 LLEMMET-DEKEGLRCQIPDSTAETLVEWLQSQMT--NGHLPGNGDVYQERLARLENDKE 114
Query: 120 SLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQ 162
SL+LQVSVLTDQVEAQGEKIRDLE CLE H+ K+NA EEMLQQ
Sbjct: 115 SLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQ 157
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 149 bits (377), Expect = 8e-36
Identities = 207/825 (25%), Positives = 350/825 (42%), Gaps = 137/825 (16%)
Query: 90 EESLSQVNHHSAASNETYQERLARLEGDKE---SLILQVSVLTDQVEAQG---EKIRDLE 143
EE Q+ + + Q+ + + E E L +++ LT E G E++R LE
Sbjct: 379 EEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLE 438
Query: 144 VCLEGHQVKLNAAE--EMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEK 201
LE +L A E + +E R S +L +TE +E +L+L +++ EEK
Sbjct: 439 GQLEEKNQELQRARQREKMNEEHNKRLSDTVDRL--LTESNE-RLQL-HLKERMAALEEK 494
Query: 202 QRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQV-ALKDAEIERLHSQ 260
L+QE + +EE +++ + +++ ++E+ QL+ + +L + I R H
Sbjct: 495 N----VLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLD 550
Query: 261 LSRT------AALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVK 314
S + + S+S + I+R + G + +E K + + + +++ + +
Sbjct: 551 TSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVR-RDEPKVKSLGD-----HEWNRTQ 604
Query: 315 EIVMVTQGPSERTLS---INEEEPEGGFSKWN----ATNKDPEEL--FKQEMPPRCSSPT 365
+I +++ P E I++++ E FS + + + D + L QE +
Sbjct: 605 QIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKE- 663
Query: 366 VGPPPLPQKSLETRAQ----KKLSCSLEDLR------------SESVDKCMDGNQPFPVL 409
+ ++S E RA+ + S SLE L S + + P
Sbjct: 664 IRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHS 723
Query: 410 EPKDSPFLAEHKYP-----TLPGKLSG-----ATPNGEAAKSPPTI-CQ--PDATGSSLL 456
PK +P + TLP L A + + TI C+ P T +L
Sbjct: 724 TPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRALR 783
Query: 457 RLRDTESGWDDTA-----VVNDLSSTSSGTESGPQSPLTPDGKRNPKGIK----KFWGKI 507
S + + A V + S G+ + Q L K+ KGIK + +GK
Sbjct: 784 MTHTLPSSYHNDARSSLSVSLEPESLGLGSANSSQDSLHKAPKK--KGIKSSIGRLFGKK 841
Query: 508 RRTQSGNF--YTDTLGMAEFRRG----GLRATAGPRLSRTRDSKGQKSDANAPFAQWSTE 561
+ + G + +T A+ G G +A RL + + + PFAQW
Sbjct: 842 EKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGP 901
Query: 562 RVCAWLEDF-GL-AQYVIFARQWVSSGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAI 619
V AWLE + G+ A YV R V SG + + ++++E+GI +PLHR KL LA++ +
Sbjct: 902 TVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEM 961
Query: 620 ---------------------------------NTKQEEKSAL--------------LDH 632
TK+ E+ + ++H
Sbjct: 962 VSLTSPSAPPTSRTPSGNVWVTHEEMENLAAPAKTKESEEGSWAQCPVFLQTLAYGDMNH 1021
Query: 633 IWV-TRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDL-LFLKVTSQLHHLSIKCAIHVL 690
W+ WL +GLPQY+ F E VD RML +LT DL + LK+ H S++ I L
Sbjct: 1022 EWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCL 1081
Query: 691 HVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLII 750
++ L RR + S +V+ WSN RV+ W++++ L EYA N+ SGVHG LI
Sbjct: 1082 KRLNYDRKELERR-REASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIA 1140
Query: 751 LEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKRE 795
L+ F +LA+LL IP Q T R+ L ++N L+ E+ E
Sbjct: 1141 LDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDE 1185
Score = 42.4 bits (98), Expect = 0.002
Identities = 45/228 (19%), Positives = 100/228 (43%), Gaps = 16/228 (7%)
Query: 90 EESLSQVNHHSAASNE---TYQERLARLEGDKESLILQVSVLTDQVEAQGEK-IRDLEVC 145
+E L + N+ A E R+ +E + E+ + + T+++ + ++ IR+
Sbjct: 274 QELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDL-IKTEEMNTKYQRDIREAMAQ 332
Query: 146 LEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKA 205
E + ++ E+ TS+ L E++ + L ME++ R+ +E+ A
Sbjct: 333 KEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELA 392
Query: 206 EELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTA 265
E+ LQ+ + E+E E Q L + ++E++ + ++E + +L R
Sbjct: 393 EQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRAR 452
Query: 266 ALH--SESHTER---------DQEIQRLKMGMETLLLANEDKDRRIEE 302
+E H +R + +RL++ ++ + A E+K+ I+E
Sbjct: 453 QREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQE 500
>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
Length = 1194
Score = 148 bits (374), Expect = 2e-35
Identities = 193/784 (24%), Positives = 311/784 (39%), Gaps = 103/784 (13%)
Query: 87 EWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCL 146
E E +Q+ AA N+ +ER G+ E + Q+ ++ + ++ R E
Sbjct: 369 ETLPEIEAQLAQRVAALNKA-EER----HGNFEERLRQLEAQLEEKNQELQRARQREKMN 423
Query: 147 EGHQVKLNAAEEMLQQELLSRTSLET-QKLDLMTEVSELKLKLVGMEKEQREQEEKQRKA 205
+ H +L+ + L E R L +++ + E + L ++ M+K Q +E
Sbjct: 424 DDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQ---DELLLNK 480
Query: 206 EELLQELRHLKIKVEELENER-NQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRT 264
E+LL E+ +++++++L + Y L + E+ Q A ++ + R
Sbjct: 481 EQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAHLDPYVAGSGRA 540
Query: 265 A--ALHSESHTERDQEIQR-LKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQ 321
S E ++ +R G E EE G+ E++ +
Sbjct: 541 GKRGRWSGVKEEPSKDWERSAPAGSIPPPFPGELDGSDEEEAEGMFGA-----ELLSPSG 595
Query: 322 GPSERTLSINEEEPEGGFSKWNATNKDPEELFKQ---EMPPRCSSPTVGPPPLPQKSLET 378
+TL+I +E +K ++ +E +Q E+ R SS L++
Sbjct: 596 QADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSS----------SGLDS 645
Query: 379 RAQKKLSCSLEDLRSESV---DKCMDGNQPFPVLEPKDSPFLAEHKYPTLPGKLSGATPN 435
+ + SCSL + S P L P K +P + +GA P
Sbjct: 646 LGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTDKANHVPKEEAGA-PR 704
Query: 436 GEAAKSPPTICQPDATGSSLLRLRDTESGWDDTAVVNDLSSTSSGTESGPQS-PLTPDGK 494
GE P P + L R+ T++ + D G+E P S P K
Sbjct: 705 GEGPAIPGDTPPPTPRSARLERM--TQALALQAGSLED-GGPPRGSEGTPDSLHKAPKKK 761
Query: 495 RNPKGIKKFWGKIRRTQSG----------------NFYTDTLGMAEFRRGGLRATAGPRL 538
I + +GK + + G TD LG+A+ G + R
Sbjct: 762 SIKSSIGRLFGKKEKGRMGPPGRDSSSLAGTPSDETLATDPLGLAKLTGPGDKDR---RN 818
Query: 539 SRTRDSKGQKSDANAPFAQWSTERVCAWLEDF-GL-AQYVIFARQWVSSGHTLLTATPQD 596
R + + PFA W V +WLE + G+ A YV R V SG + + +
Sbjct: 819 KRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTE 878
Query: 597 MEKELGIKHPLHRKKLVLAVKAI-------------------------------NTKQEE 625
+++E+GI +PLHR KL LA++ + TK E
Sbjct: 879 IQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTSTGNVWMTHEEMESLTATTKPET 938
Query: 626 KSAL---------LDHIWVTR-WLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLF-LKV 674
K ++H WV WL +GLPQY+ F ES VD RML +L +L LK+
Sbjct: 939 KEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKM 998
Query: 675 TSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAE 734
H +S+ I L ++ L RR +ES +V+ WSN RVM W+ + L E
Sbjct: 999 VDSFHRVSLHYGIMCLKRLNYDRKDLERR-REESQTQIRDVMVWSNERVMGWVSGLGLKE 1057
Query: 735 YAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKR 794
+A NL SGVHG L+ L+ F LA+LL IP Q R+ L +F+ LI ++
Sbjct: 1058 FATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLD 1117
Query: 795 EKMA 798
E A
Sbjct: 1118 EDSA 1121
Score = 39.3 bits (90), Expect = 0.016
Identities = 57/208 (27%), Positives = 91/208 (43%), Gaps = 18/208 (8%)
Query: 106 TYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELL 165
T Q RL L +K+SL Q+S+ Q A K +L +C E +L EE + +
Sbjct: 55 TAQLRLRELGHEKDSLQRQLSIALPQEFAALTK--ELNLCRE----QLLEREEEIAELKA 108
Query: 166 SR--TSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELE 223
R T L + L+ + E L++ + K Q + E+L+ L+ L + L+
Sbjct: 109 ERNNTRLLLEHLECLVSRHERSLRMT-VVKRQAQSPGGVSSEVEVLKALKSLFEHHKALD 167
Query: 224 NERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLK 283
+ + +L+ VA L+E++ L + E L QLSR + E +D + Q L
Sbjct: 168 EKVRE---RLRMALERVAVLEEELELSNQETLNLREQLSRRRSGLEE--PGKDGDGQTLA 222
Query: 284 MGMETLLLANEDKDRRIEELTGLLNQYR 311
G L D +RR EL L + R
Sbjct: 223 NG----LGPGGDSNRRTAELEEALERQR 246
Score = 39.3 bits (90), Expect = 0.016
Identities = 54/238 (22%), Positives = 104/238 (43%), Gaps = 28/238 (11%)
Query: 97 NHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGH-QVKLNA 155
N +A E + + A + +E L + ++ E G R+L E + +++ +
Sbjct: 232 NRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDL 291
Query: 156 AEEMLQQELLSR--TSLETQKLDLMTEVS-------ELKLKLVGMEKEQREQEEKQRKAE 206
E + Q+E + T+LE + L E + +L+ +L E R+ EEK R+
Sbjct: 292 KEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLA 351
Query: 207 ELL----QELRHLKIKVEELENERNQYEWKLKA-TKAEV--AQLQEQVALKDAEIERLHS 259
E L Q+L+ K E L Q ++ A KAE +E++ +A++E +
Sbjct: 352 EWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQ 411
Query: 260 QLSRTAALH--SESHTERDQEI---------QRLKMGMETLLLANEDKDRRIEELTGL 306
+L R ++ H +R E +RL++ ++ + A E+K+ EE+ +
Sbjct: 412 ELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANM 469
>gi|55769554 protein tyrosine phosphatase, receptor type, f
polypeptide (PTPRF), interacting protein (liprin), alpha
4 [Homo sapiens]
Length = 701
Score = 137 bits (345), Expect = 4e-32
Identities = 96/301 (31%), Positives = 144/301 (47%), Gaps = 45/301 (14%)
Query: 529 GLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDF-GL-AQYVIFARQWVSSG 586
G +A RL + PFAQW V +WLE + G+ A YV R V SG
Sbjct: 316 GTQAEKDRRLKKKHQLLEDARRKGMPFAQWDGPTVVSWLELWVGMPAWYVAACRANVKSG 375
Query: 587 HTLLTATPQDMEKELGIKHPLHRKKLVLAVKAI--------------------------- 619
+ + ++++E+GI + LHR KL LA++ +
Sbjct: 376 AIMSALSDTEIQREIGISNALHRLKLRLAIQEMVSLTSPSAPPTSRTSSGNVWVTHEEME 435
Query: 620 ------NTKQEEKSAL-------LDHIWV-TRWLDDIGLPQYKDQFHESRVDGRMLQYLT 665
T EE S ++H W+ WL +GLPQY+ F E VD RML +LT
Sbjct: 436 TLETSTKTDSEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLT 495
Query: 666 VNDL-LFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVM 724
DL + LK+ H S++ I L ++ L +R +ES +V+ W+N +V+
Sbjct: 496 KKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELEKR-REESQHEIKDVLVWTNDQVV 554
Query: 725 EWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNAL 784
W++S+ L +YA NL SGVHG L+ L+ F +TLA++L IP Q T R+ + +FN L
Sbjct: 555 HWVQSIGLRDYAGNLHESGVHGALLALDENFDHNTLALILQIPTQNTQARQVMEREFNNL 614
Query: 785 I 785
+
Sbjct: 615 L 615
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 70.1 bits (170), Expect = 9e-12
Identities = 85/350 (24%), Positives = 158/350 (45%), Gaps = 26/350 (7%)
Query: 65 ELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNE--TYQERLARLEGDKESLI 122
+L ++ +AL SQ+ T ++E + LS +E +++E+L E K +L
Sbjct: 1298 KLTKDFSALESQLQD-TQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLE 1356
Query: 123 LQVSVLTDQVEAQGEKIRDLEVCLE-GHQVK------LNAAEEMLQQELLSRTSLETQKL 175
Q++ L QV +K+ D CLE +VK L + ++++ + LE K
Sbjct: 1357 KQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKT 1416
Query: 176 DLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKA 235
L E+ +L + L + E+KQ+K ++LL E + + K E E +R + E + K
Sbjct: 1417 RLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAE-ERDRAEAEAREKE 1475
Query: 236 TKA-EVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANE 294
TKA +A+ E+ + AE+ERL+ Q S + + + L+ L
Sbjct: 1476 TKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL----- 1530
Query: 295 DKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSK-WNATNKDPEELF 353
++++EE+ Q ++++ + T+ R L +N + + F + ++ EE
Sbjct: 1531 --EQQVEEMK---TQLEELEDELQATEDAKLR-LEVNLQAMKAQFERDLQGRDEQSEEKK 1584
Query: 354 KQEMPPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRS--ESVDKCMD 401
KQ + Q+S+ A+KKL L+DL + +S +K D
Sbjct: 1585 KQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRD 1634
Score = 60.8 bits (146), Expect = 5e-09
Identities = 59/243 (24%), Positives = 114/243 (46%), Gaps = 37/243 (15%)
Query: 90 EESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQV----------------- 132
++ L ++ H A E +ER L+ +K+ + + L +Q+
Sbjct: 910 KQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTT 969
Query: 133 EAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGM- 191
EA+ +K+ + ++ LE KL +++L+ + T+ T++ + +++LK K M
Sbjct: 970 EAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMI 1029
Query: 192 ----------EKEQREQEEKQRKAE----ELLQELRHLKIKVEELENERNQYEWKLKATK 237
EK+++E E+ +RK E +L ++ L+ ++ EL+ + + E +L+A
Sbjct: 1030 TDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAAL 1089
Query: 238 AEVAQ--LQEQVALKDAEIERLHSQLSRTAA-LHSESHTERDQEIQRLKMGMETLLLANE 294
A V + Q+ +ALK +I L SQ+S L SE + E Q+ +G E L E
Sbjct: 1090 ARVEEEAAQKNMALK--KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTE 1147
Query: 295 DKD 297
+D
Sbjct: 1148 LED 1150
Score = 52.0 bits (123), Expect = 2e-06
Identities = 66/300 (22%), Positives = 129/300 (43%), Gaps = 22/300 (7%)
Query: 114 LEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQ 173
LE ++ L +V VL K + +E L+ QVK N E + + T L+ +
Sbjct: 1222 LENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVE 1281
Query: 174 KLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKI----KVEELENERNQY 229
++ +S+ K + K+ E + + +ELLQE K+ K++++E+E+N +
Sbjct: 1282 LDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSF 1341
Query: 230 EWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQR-LKMGMET 288
+L+ + L++Q+A A++ + ++ S E +E++R L+ +E
Sbjct: 1342 REQLEEEEEAKHNLEKQIATLHAQVADMKKKME-----DSVGCLETAEEVKRKLQKDLEG 1396
Query: 289 LLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKD 348
L +E+K ++L + ++ + ++V +R + N E+ + F + A K
Sbjct: 1397 LSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDL-DHQRQSACNLEKKQKKFDQLLAEEKT 1455
Query: 349 -----PEELFKQEMPPR------CSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVD 397
EE + E R S + QK+ R K+ +EDL S D
Sbjct: 1456 ISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDD 1515
Score = 51.2 bits (121), Expect = 4e-06
Identities = 48/218 (22%), Positives = 103/218 (47%), Gaps = 24/218 (11%)
Query: 122 ILQVSVLTDQVEAQGE---KIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLM 178
+LQVS +++ A+ E K+R+ ++ E ++ + L E L + +L
Sbjct: 837 LLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELC 896
Query: 179 TEVSELKLKLVGMEKEQR-----------EQEEK----QRKAEELLQELRHLKIKVEELE 223
E EL+ +L ++E E+EE+ Q + +++ Q ++ L+ ++EE E
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 224 NERNQYEWKLKATKAEVAQL-QEQVALKD-----AEIERLHSQLSRTAALHSESHTERDQ 277
+ R + + + T+A++ +L +EQ+ L+D A+ ++L + E+ +
Sbjct: 957 SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSK 1016
Query: 278 EIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKE 315
+ +LK E ++ E++ RR E+ L + R+ E
Sbjct: 1017 SLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLE 1054
Score = 49.3 bits (116), Expect = 2e-05
Identities = 61/260 (23%), Positives = 115/260 (44%), Gaps = 33/260 (12%)
Query: 68 QERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSV 127
+E++ L+++ A I + EE L + +T + +LEGD
Sbjct: 1012 EEKSKSLAKLKNKHEAMITD-LEERLRREEKQRQELEKTRR----KLEGDSTD------- 1059
Query: 128 LTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLK 187
L+DQ+ +I +L++ L + +L AA +++E + + +L +++SEL+
Sbjct: 1060 LSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQED 1119
Query: 188 LVGMEKEQREQEEKQRKAEELLQELRHLKIKVE----------ELENERNQYEWKLKAT- 236
L E+ R + EKQ++ +L +EL LK ++E EL ++R Q LK T
Sbjct: 1120 LES-ERASRNKAEKQKR--DLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTL 1176
Query: 237 ----KAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTER---DQEIQRLKMGMETL 289
K AQ+QE +E L QL +T + + + + E L ++ L
Sbjct: 1177 EEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236
Query: 290 LLANEDKDRRIEELTGLLNQ 309
L D + + +++ L +
Sbjct: 1237 LQGKGDSEHKRKKVEAQLQE 1256
Score = 46.2 bits (108), Expect = 1e-04
Identities = 68/297 (22%), Positives = 131/297 (44%), Gaps = 25/297 (8%)
Query: 108 QERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSR 167
+E ARL K+ L L +VE + E+ + L+ + Q + EE L++E +R
Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959
Query: 168 TSLETQKLDLMTEVSELKLKLVGMEKEQ---REQEEKQRKAEELLQE-LRHLKIKVEELE 223
QKL L +E KLK +E+EQ +Q K K ++LL++ + + E E
Sbjct: 960 -----QKLQLEKVTTEAKLK--KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTE-E 1011
Query: 224 NERNQYEWKLK-ATKAEVAQLQEQVALKD---AEIERLHSQLSRTAALHSESHTERDQEI 279
E+++ KLK +A + L+E++ ++ E+E+ +L + S+ E +I
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQI 1071
Query: 280 QRLKMGMETLLLANEDKDRRIEELTGLLNQ-YRKVKEIVMVTQGPSERTLSINEEEPEGG 338
LKM + + R+EE N +K++E+ E +S +E+ E
Sbjct: 1072 AELKMQLAKKEEELQAALARVEEEAAQKNMALKKIREL--------ESQISELQEDLESE 1123
Query: 339 FSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSES 395
+ N K +L ++ + Q+ L ++ +++++ + L E+
Sbjct: 1124 RASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEA 1180
Score = 43.1 bits (100), Expect = 0.001
Identities = 37/159 (23%), Positives = 80/159 (50%), Gaps = 6/159 (3%)
Query: 108 QERLARLEGDKESLILQVSVLTDQV-EAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLS 166
QE LA E K + L D++ + G+ LE + ++ EE L++E +
Sbjct: 1686 QEELAAAERAKRQAQQERDELADEIANSSGKGALALEE-KRRLEARIAQLEEELEEEQGN 1744
Query: 167 RTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENE- 225
+ + ++ ++ L +E+ ++ E R ++L ++ + LK+K++E+E
Sbjct: 1745 TELINDRLKKANLQIDQINTDL-NLERSHAQKNENAR--QQLERQNKELKVKLQEMEGTV 1801
Query: 226 RNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRT 264
+++Y+ + A +A++AQL+EQ+ + E + Q+ RT
Sbjct: 1802 KSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRT 1840
Score = 42.7 bits (99), Expect = 0.001
Identities = 59/253 (23%), Positives = 107/253 (42%), Gaps = 52/253 (20%)
Query: 102 ASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQ 161
+S + + + LE K +L QV + Q+E ++++ E +V L A + +
Sbjct: 1511 SSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570
Query: 162 QELLSRTSL-ETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKA--------------- 205
++L R E +K L+ +V E++ +L E++QR RK
Sbjct: 1571 RDLQGRDEQSEEKKKQLVRQVREMEAELED-ERKQRSMAVAARKKLEMDLKDLEAHIDSA 1629
Query: 206 ----EELLQELRHLKIKV--------------EELENERNQYEWKLKATKAEVAQLQEQV 247
+E +++LR L+ ++ EE+ + + E KLK+ +AE+ QLQE++
Sbjct: 1630 NKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEEL 1689
Query: 248 ALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDR---RIEELT 304
A ER Q + ERD+ + LA E+K R RI +L
Sbjct: 1690 ----AAAERAKRQ----------AQQERDELADEIANSSGKGALALEEKRRLEARIAQLE 1735
Query: 305 GLLNQYRKVKEIV 317
L + + E++
Sbjct: 1736 EELEEEQGNTELI 1748
Score = 41.2 bits (95), Expect = 0.004
Identities = 63/291 (21%), Positives = 121/291 (41%), Gaps = 45/291 (15%)
Query: 54 IEDLRLALEMLE---LPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQER 110
+E+++ LE LE E A L ++ +K FE L + S + +
Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEV---NLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 111 LARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQ--------- 161
+ +E + E Q S+ + ++DLE ++ + A + L+
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDC 1650
Query: 162 -----------QELLSRTSLETQKLDLM-TEVSELKLKLVGMEKEQRE-QEEKQRKAEEL 208
+E+L++ +KL M E+ +L+ +L E+ +R+ Q+E+ A+E+
Sbjct: 1651 MRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1710
Query: 209 ----------LQELRHLKIKVEELENE--RNQYEWKLKATKAEVAQLQEQVALKDAEIER 256
L+E R L+ ++ +LE E Q +L + + A LQ D +ER
Sbjct: 1711 ANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLER 1770
Query: 257 LHSQLSRTAALHSESHTE----RDQEIQ-RLKMGMETLLLANEDKDRRIEE 302
H+Q + A E + + QE++ +K + + A E K ++EE
Sbjct: 1771 SHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1821
Score = 38.9 bits (89), Expect = 0.021
Identities = 34/142 (23%), Positives = 66/142 (46%), Gaps = 9/142 (6%)
Query: 131 QVEAQGEKIRDLEVCLEG-----HQVKLNAAEEMLQQ--ELLSRTSLETQKLDLMTEVSE 183
Q+E Q ++++ +EG ++ + A E + Q E L + E Q +E
Sbjct: 1782 QLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTE 1841
Query: 184 LKLK--LVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVA 241
KLK L+ ++ E+R E+ + +A++ L+ LK ++EE E E + + + E+
Sbjct: 1842 KKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELE 1901
Query: 242 QLQEQVALKDAEIERLHSQLSR 263
E + E+ L ++L R
Sbjct: 1902 DATETADAMNREVSSLKNKLRR 1923
Score = 38.1 bits (87), Expect = 0.036
Identities = 51/229 (22%), Positives = 95/229 (41%), Gaps = 19/229 (8%)
Query: 118 KESLILQVSVLTDQVEAQGEKIRDL----EVCLEGHQVKLNAAEEMLQ---QELLSRTSL 170
+ + + VL E + KI D+ + C G+ + A+ Q ++L R
Sbjct: 758 QSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCA 817
Query: 171 ETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEEL--ENERNQ 228
KL + L K+ + + R++EE K EEL+ K++ ++L EN +
Sbjct: 818 AYLKLRNW-QWWRLFTKVKPLLQVSRQEEEMMAKEEELV------KVREKQLAAENRLTE 870
Query: 229 YEWKLKATKAEVAQLQEQVALKD---AEIERLHSQLSRTAALHSESHTERDQEIQRLKMG 285
E AE QLQEQ+ + AE E L ++L+ E + + ++ +
Sbjct: 871 METLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEER 930
Query: 286 METLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEE 334
+ L + + I+EL L + ++ + + + +E L EEE
Sbjct: 931 CQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 62.0 bits (149), Expect = 2e-09
Identities = 80/287 (27%), Positives = 130/287 (45%), Gaps = 35/287 (12%)
Query: 104 NETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEV---CLEGHQVKLNAAEEML 160
+E E L L+ + ++L ++S LTDQV G+ I++LE LEG + ++ AA E
Sbjct: 1537 HEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEA 1596
Query: 161 QQEL-LSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQ-----ELRH 214
+ L L T +L+L +E+ KL ++E ++A E LQ E R
Sbjct: 1597 EGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRA 1656
Query: 215 ----LKIKVEELENERNQYEWKL-----KATKAEVA------QLQEQVALKDAE---IER 256
L++K +++E + N E +L +AT+A+ A QL+E+ A +D E
Sbjct: 1657 RNEALRLK-KKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAE 1715
Query: 257 LHSQ---LSRTAALHS----ESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQ 309
LH Q L R A+L + E +Q + ++ + LL A E + + TGLLNQ
Sbjct: 1716 LHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQ 1775
Query: 310 YRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQE 356
+K++ + G E E E EEL K++
Sbjct: 1776 KKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQ 1822
Score = 56.2 bits (134), Expect = 1e-07
Identities = 62/258 (24%), Positives = 115/258 (44%), Gaps = 42/258 (16%)
Query: 54 IEDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLAR 113
I+DL+L L E +E+ A +++ T +ES++++ A E +Q+ L
Sbjct: 1003 IDDLKLTLAKAE--KEKQATENKVKNLTEEMAA--LDESVARLTKEKKALQEAHQQALGD 1058
Query: 114 LEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQ 173
L+ +++ +VS LT +++ DLE LE QE R E
Sbjct: 1059 LQAEED----RVSALTKAKLRLEQQVEDLECSLE--------------QEKKLRMDTERA 1100
Query: 174 KLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVE------------- 220
K L ++ + + +++++ EEK +K + EL L ++VE
Sbjct: 1101 KRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDS---ELSQLSLRVEDEQLLGAQMQKKI 1157
Query: 221 -ELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSR---TAALHSESHTERD 276
EL+ + E +L+A +A A++++Q A E+E L +L +A E +R+
Sbjct: 1158 KELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKRE 1217
Query: 277 QEIQRLKMGMETLLLANE 294
E+ RL+ +E L +E
Sbjct: 1218 AELGRLRRELEEAALRHE 1235
Score = 50.1 bits (118), Expect = 9e-06
Identities = 66/313 (21%), Positives = 126/313 (40%), Gaps = 32/313 (10%)
Query: 90 EESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGH 149
EE + N A + ++ RL+ + E + L++ T A +K R LE LE
Sbjct: 1450 EEGVEAAN----AKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEER 1505
Query: 150 QVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKL----KLVGMEKEQREQEEKQRKA 205
+ + EE +Q+EL + + + L TE+ L+ L +E +RE + Q +
Sbjct: 1506 RRQ----EEEMQREL---EAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEI 1558
Query: 206 EELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTA 265
+L ++ ++ELE + E + +A + + + + L++ + R+ +LS+
Sbjct: 1559 SDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVK 1618
Query: 266 ALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSE 325
A E+D+E L+ + R +E L L+ + + + + E
Sbjct: 1619 AEVDRKLAEKDEECANLR----------RNHQRAVESLQASLDAETRARNEALRLKKKME 1668
Query: 326 RTLSINEEEPEGGFSKWNATNKDP-----EELFKQEMPPRCSSPTVGPPPLPQKSLETRA 380
L N+ E + G + AT + K+E R + Q R
Sbjct: 1669 GDL--NDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERR 1726
Query: 381 QKKLSCSLEDLRS 393
L+ LE+LR+
Sbjct: 1727 ASLLAAELEELRA 1739
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/213 (23%), Positives = 95/213 (44%), Gaps = 11/213 (5%)
Query: 102 ASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL---EVCLEGHQVKLNAA-- 156
A + +E + +K L LQ+ D + E+ L +V LEG +L+
Sbjct: 917 AKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLE 976
Query: 157 -EEMLQQELLSRT-SLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEE----LLQ 210
EE + +L +R LE + +L ++ +LKL L EKE++ E K + E L +
Sbjct: 977 DEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDE 1036
Query: 211 ELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSE 270
+ L + + L+ Q L+A + V+ L + + ++E L L + L +
Sbjct: 1037 SVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMD 1096
Query: 271 SHTERDQEIQRLKMGMETLLLANEDKDRRIEEL 303
+ + + LK+ E++ A +DK + E+L
Sbjct: 1097 TERAKRKLEGDLKLTQESVADAAQDKQQLEEKL 1129
Score = 47.0 bits (110), Expect = 8e-05
Identities = 48/197 (24%), Positives = 87/197 (44%), Gaps = 22/197 (11%)
Query: 141 DLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEE 200
DL + L+ Q L AEE + S+ LE + V EL +L E+ +
Sbjct: 935 DLALQLQAEQDNLADAEERCHLLIKSKVQLEGK-------VKELSERLEDEEEVNADLAA 987
Query: 201 KQRKAE----ELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIER 256
++RK E EL +++ LK+ + + E E+ E K+K E+A L E VA
Sbjct: 988 RRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVA-------- 1039
Query: 257 LHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEI 316
+L++ E+H + ++Q + + L A ++++E+L L Q +K++
Sbjct: 1040 ---RLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMD 1096
Query: 317 VMVTQGPSERTLSINEE 333
+ E L + +E
Sbjct: 1097 TERAKRKLEGDLKLTQE 1113
Score = 44.7 bits (104), Expect = 4e-04
Identities = 66/234 (28%), Positives = 104/234 (44%), Gaps = 28/234 (11%)
Query: 54 IEDLRLALEMLE--LPQERAALLS-QIPGPTAAYIKEWFEESLSQVNHHSAASNETYQER 110
I++L+ E LE L ERAA + AA E E L + SA E ++R
Sbjct: 1157 IKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKR 1216
Query: 111 LARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLE-GHQVKLNAAEEMLQQELLSRTS 169
A L + L + + L + + + E E G QV + LQ+ R
Sbjct: 1217 EAELGRLRREL--EEAALRHEATVAALRRKQAEGAAELGEQV------DSLQRV---RQK 1265
Query: 170 LETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELEN---ER 226
LE +K +L EV +L + + + + E+ R E+ L E KIKVEEL+ +
Sbjct: 1266 LEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEA---KIKVEELQRQLADA 1322
Query: 227 NQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQ 280
+ +L+ E+++L E E E L SQLSR AL ++S E ++++
Sbjct: 1323 STQRGRLQTESGELSRLLE-------EKECLISQLSRGKALAAQSLEELRRQLE 1369
Score = 43.5 bits (101), Expect = 9e-04
Identities = 70/286 (24%), Positives = 114/286 (39%), Gaps = 55/286 (19%)
Query: 62 EMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASN----------------- 104
E+ L +E+ L+SQ+ A + EE Q+ S A +
Sbjct: 1335 ELSRLLEEKECLISQLSRGKALAAQS-LEELRRQLEEESKAKSALAHAVQALRHDCDLLR 1393
Query: 105 ---ETYQERLARLEGDKESLILQVSVLTDQVEAQG-EKIRDLEVCLEGHQVKLNAAEEML 160
E E A L+ +V+ + EA ++ +LE + ++L AEE +
Sbjct: 1394 EQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGV 1453
Query: 161 QQELLSRTSLETQKLDLMTEVSELKLKL-------VGMEKEQRE----QEEKQRKAEELL 209
+ +SLE KL L TE ++ L+L ++K+QR EE++R+ EE+
Sbjct: 1454 EAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQ 1513
Query: 210 QELRHLKIKVEELENE----RNQYEWKLKATKA----------EVAQLQEQVALKDAEIE 255
+EL + + L E R+ +E L+A + E++ L +QV+L I+
Sbjct: 1514 RELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQ 1573
Query: 256 RLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIE 301
L AL E EIQ E L E K RI+
Sbjct: 1574 ELE---KTKKALEGEK-----SEIQAALEEAEGALELEETKTLRIQ 1611
Score = 38.9 bits (89), Expect = 0.021
Identities = 55/245 (22%), Positives = 104/245 (42%), Gaps = 55/245 (22%)
Query: 102 ASNETYQERLARLEGDKESLILQVSVLTDQVEA------QGEKIRDLEVCLEGHQVKLNA 155
A + Q A L ++L + S+L ++E QGE+ R L + +L
Sbjct: 1704 AGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLA------EQELLE 1757
Query: 156 AEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKA--------EE 207
A E L T L QK L ++++L ++ +E+RE EEK +KA EE
Sbjct: 1758 ATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEE 1817
Query: 208 LLQE-----------------LRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALK 250
L +E +R L+ ++EE E + L+ K +V +L+ +V
Sbjct: 1818 LKKEQDTSAHLERMKKTLEQTVRELQARLEEAE------QAALRGGKKQVQKLEAKVREL 1871
Query: 251 DAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQY 310
+AE++ + H E + +++ + ++ L E+ + + + L+++
Sbjct: 1872 EAELD-----------AEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKL 1920
Query: 311 R-KVK 314
+ KVK
Sbjct: 1921 QSKVK 1925
Score = 38.1 bits (87), Expect = 0.036
Identities = 58/251 (23%), Positives = 97/251 (38%), Gaps = 26/251 (10%)
Query: 54 IEDLRLALEMLELPQERAAL-LSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLA 112
+E+ ALE+ E R L LSQ+ + E EE + +H A A
Sbjct: 1593 LEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDA 1652
Query: 113 RLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLET 172
E+L L+ + D + DLE+ L GH + A E L+
Sbjct: 1653 ETRARNEALRLKKKMEGD--------LNDLELQL-GHATR-QATEAQAATRLMQ------ 1696
Query: 173 QKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWK 232
++LK + G ++EQR E +A+ L + L ++EEL Q E
Sbjct: 1697 ---------AQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERS 1747
Query: 233 LKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLA 292
+ + E+ + E++ L ++ L +Q + A ++ E ++ Q + E A
Sbjct: 1748 RRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKA 1807
Query: 293 NEDKDRRIEEL 303
D EEL
Sbjct: 1808 ITDAAMMAEEL 1818
Score = 35.8 bits (81), Expect = 0.18
Identities = 71/295 (24%), Positives = 121/295 (41%), Gaps = 50/295 (16%)
Query: 54 IEDLRLALEM---LELPQERAAL-------LSQIPGPTAAYIKEWFEESLSQVNHH-SAA 102
+EDL +LE L + ERA L+Q AA K+ EE L + + S
Sbjct: 1080 VEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQL 1139
Query: 103 SNETYQERL--ARLEGDKESLILQVSVLTDQVEAQ-----------GEKIRDLEVCLEGH 149
S E+L A+++ + L + L +++EA+ E R+LE E
Sbjct: 1140 SLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERL 1199
Query: 150 QVKLNAAEEMLQ-----QELLSRTSLETQKLDLMTE--VSELKLKLVGMEKEQREQEEK- 201
+ A+ + + L R E ++ L E V+ L+ K E EQ +
Sbjct: 1200 EEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSL 1259
Query: 202 QRKAEELLQELRHLKIKVEEL--------------ENERNQYEWKLKATKAEVAQLQEQV 247
QR ++L +E L+++V++L E YE +L K +V +LQ Q+
Sbjct: 1260 QRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQL 1319
Query: 248 ALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEE 302
A + RL ++ + L E++ I +L G + E+ R++EE
Sbjct: 1320 ADASTQRGRLQTESGELSRLLE----EKECLISQLSRGKALAAQSLEELRRQLEE 1370
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 61.6 bits (148), Expect = 3e-09
Identities = 79/334 (23%), Positives = 136/334 (40%), Gaps = 42/334 (12%)
Query: 87 EWFEESLSQVNHHSAASN---ETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLE 143
E +SL+ V +A N +T RLA L+ +++ LI ++ + ++ L+
Sbjct: 1514 ERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLK 1573
Query: 144 VCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQR 203
+ LEG L +E L +E+ SL++ K+ TE E +L Q+E E +
Sbjct: 1574 LALEG----LTEDKEKLVKEI---ESLKSSKIAESTEWQEKHKEL------QKEYEILLQ 1620
Query: 204 KAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSR 263
E + E ++ VE + E+ + KL++T+A + ++Q+ + E+E + ++ +
Sbjct: 1621 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK 1680
Query: 264 TAALHSESHTERDQEIQRL-----------KMGMETLLLANEDKDRRIEELTGLLNQYRK 312
A + E ++E RL K METLL +N +E + K
Sbjct: 1681 FAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSK 1740
Query: 313 VKEIVMVTQGPSERTLSINEEEPEGGFSK---WNATNKDPEELFKQEMPPRCSSPTVGPP 369
+ +M + + + + EG SK AT K + E G
Sbjct: 1741 KFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTE---------EGTQ 1791
Query: 370 PLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGN 403
+P ET Q LS S SESV N
Sbjct: 1792 SIPG---ETEEQDSLSMSTRPTCSESVPSAKSAN 1822
Score = 60.1 bits (144), Expect = 9e-09
Identities = 67/295 (22%), Positives = 128/295 (43%), Gaps = 31/295 (10%)
Query: 85 IKEWFEESLSQVNHHSAASNETYQERLARLEGDKE-SLILQVSVLTDQVE---AQGEKIR 140
+ + EE +++S+A +ER L KE S++ ++ Q+E A+ E+ R
Sbjct: 721 LNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQR 780
Query: 141 DLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQRE--- 197
L+ + A + L E + S+E + D+ EV + +L V ++ ++
Sbjct: 781 RLDY-------ESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLI 833
Query: 198 ---QEEKQRKAEELLQ---ELRHLKIKVEELENERNQYEWK-------LKATKAEVAQLQ 244
Q + Q K E+L+ +RH+ KVEEL +Q E + L K +V LQ
Sbjct: 834 RSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQ 893
Query: 245 EQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEE-- 302
+ + KD ++ + ++ +E EI+ LK + L A E K ++EE
Sbjct: 894 QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDN 953
Query: 303 --LTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQ 355
+GL Y ++ +++ + + ++E E K A + +EL ++
Sbjct: 954 EVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1008
Score = 53.1 bits (126), Expect = 1e-06
Identities = 52/220 (23%), Positives = 102/220 (46%), Gaps = 25/220 (11%)
Query: 91 ESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQ 150
ESL V+H + E+ Q++L ES LQ++ L E Q K+ +L+ + +
Sbjct: 1354 ESLKTVSHEAEVHAESLQQKL-------ESSQLQIAGLEHLRELQ-PKLDELQKLISKKE 1405
Query: 151 VKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQ 210
++ L ++ + T ++T+ ++ + L +L E + +E +E+ ++ + L
Sbjct: 1406 EDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQL---EMQAKEHDERIKQLQVELC 1462
Query: 211 ELRHLKIKVEELENERNQYEWKLKATKA-------EVAQLQEQVALKDAEIERLHSQLSR 263
E++ ++ E + Q + KL+A E LQE+++L IERL L+
Sbjct: 1463 EMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLAD 1522
Query: 264 TAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEEL 303
+ S + E+D + R L L E++D+ I E+
Sbjct: 1523 VESQVSAQNKEKDTVLGR-------LALLQEERDKLITEM 1555
Score = 51.2 bits (121), Expect = 4e-06
Identities = 58/252 (23%), Positives = 108/252 (42%), Gaps = 44/252 (17%)
Query: 62 EMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESL 121
++LEL +E L +++ P KE E LS SN + +E L R++ + E+L
Sbjct: 1688 KILELEEENDRLRAEVH-PAGDTAKECMETLLS--------SNASMKEELERVKMEYETL 1738
Query: 122 ILQVSVLTDQVEAQGEKIRDLEVCLEGH---QVKLNAAEEMLQQELLSRTSL-----ETQ 173
+ L + ++ E+++DL+ +EG+ Q L A E+ Q ++ ET+
Sbjct: 1739 SKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETE 1798
Query: 174 KLDLMT---------EVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKV----- 219
+ D ++ V K + K+ +E LQ++ LK ++
Sbjct: 1799 EQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDE----INNYLQQIDQLKERIAGLEE 1854
Query: 220 ---------EELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSE 270
+ LENE+N ++ E+ LQE+V + +++ +LSR L
Sbjct: 1855 EKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKET 1914
Query: 271 SHTERDQEIQRL 282
+ E+D +RL
Sbjct: 1915 AEEEKDDLEERL 1926
Score = 46.6 bits (109), Expect = 1e-04
Identities = 54/237 (22%), Positives = 102/237 (43%), Gaps = 26/237 (10%)
Query: 89 FEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEG 148
F +S+S + + YQ+ LE S+IL+ L + A+ K+++ L
Sbjct: 2462 FVKSMSSLQNDRDRIVGDYQQ----LEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRS 2517
Query: 149 HQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEEL 208
H LN+ L EL+ Q + + + S+ K L ++ +E E K K EE
Sbjct: 2518 HMDDLNSENAKLDAELIQYREDLNQVITI--KDSQQKQLLEVQLQQNKELENKYAKLEEK 2575
Query: 209 LQELRH----LKIKVEELENERNQYEWKLKATKAEVAQLQEQV---------ALKDAEIE 255
L+E L+ L+ E+ ++++ K ++QL QV L A+++
Sbjct: 2576 LKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLK 2635
Query: 256 RLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRK 312
++ R +AL S S +R E++ E L+ ++ +++ E+ L + K
Sbjct: 2636 VKEEEVHRLSALFSSSQ-KRIAELE------EELVCVQKEAAKKVGEIEDKLKKELK 2685
Score = 46.2 bits (108), Expect = 1e-04
Identities = 57/256 (22%), Positives = 113/256 (44%), Gaps = 45/256 (17%)
Query: 110 RLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTS 169
+L +E +K L L+VS T ++ + E++ L QE +++
Sbjct: 1310 QLKEIEAEKVELELKVSSTTSELTKKSEEVFQL-------------------QEQINKQG 1350
Query: 170 LETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEEL------- 222
LE + L ++ +E V E Q++ E Q + L + LR L+ K++EL
Sbjct: 1351 LEIESLKTVSHEAE-----VHAESLQQKLESSQLQIAGL-EHLRELQPKLDELQKLISKK 1404
Query: 223 ENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRL 282
E + + +L +A + ++Q ++ ++ I+ LH+QL A H E + E+ +
Sbjct: 1405 EEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1464
Query: 283 KMGMETLLLANEDKDRRIEELTG-------LLNQYRKVKEIVMVTQGPSER-TLSINEEE 334
K E + + K + +L L + + ++E + + +G ER T S+ + E
Sbjct: 1465 KQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVE 1524
Query: 335 PEGGFSKWNATNKDPE 350
S+ +A NK+ +
Sbjct: 1525 -----SQVSAQNKEKD 1535
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/237 (23%), Positives = 111/237 (46%), Gaps = 18/237 (7%)
Query: 108 QERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCL-EGHQVKLNAAEEMLQQELLS 166
+E L + + D L Q + + E G+++R L++ + E KL + + QQE S
Sbjct: 1202 REELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTD---QQESCS 1258
Query: 167 RTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENER 226
T + L TE + L + A + + +K +++E+E E+
Sbjct: 1259 STPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEK 1318
Query: 227 NQYEWKLKATKA-------EVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEI 279
+ E K+ +T + EV QLQEQ+ + EIE L + +S A +H+ES ++ +
Sbjct: 1319 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKT-VSHEAEVHAESLQQKLESS 1377
Query: 280 QRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPE 336
Q G+E L + +++EL L++ +K +++ ++ SE+ ++ + + E
Sbjct: 1378 QLQIAGLEHL----RELQPKLDELQKLIS--KKEEDVSYLSGQLSEKEAALTKIQTE 1428
Score = 45.4 bits (106), Expect = 2e-04
Identities = 57/239 (23%), Positives = 104/239 (43%), Gaps = 28/239 (11%)
Query: 83 AYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL 142
A ++E +ES + N S QE L + ESL + +S LT QV A E
Sbjct: 2570 AKLEEKLKES-EEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQE----- 2623
Query: 143 EVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQ 202
E L + +L EE + + LS +QK ++EL+ +LV ++KE ++ +
Sbjct: 2624 EGTLGLYHAQLKVKEEEVHR--LSALFSSSQK-----RIAELEEELVCVQKEAAKKVGEI 2676
Query: 203 RKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLS 262
++L +EL+HL + NE E ++ ++ ++++++ + E + L +Q+
Sbjct: 2677 E--DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQ 2734
Query: 263 RTAALHSESHTERD---QEIQRLKMGMETLL----------LANEDKDRRIEELTGLLN 308
S RD +E+ LK + L L N ++D + E +N
Sbjct: 2735 SFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMN 2793
Score = 44.3 bits (103), Expect = 5e-04
Identities = 61/235 (25%), Positives = 98/235 (41%), Gaps = 30/235 (12%)
Query: 98 HHSAA----SNETYQERLARLEGD---KESLILQVSV----LTDQVEAQGEKIRDLEVCL 146
HH A ET +ER+A L D E +L V+ LT Q+++ G + L+
Sbjct: 2688 HHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSR 2747
Query: 147 EGHQVKLNAAEEMLQQELLSRTSLETQKL---DLMTEVSELKLKLVGMEKEQREQEEKQR 203
+ +L+ + L L+ Q L + +SE + E+ EK
Sbjct: 2748 DHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLN 2807
Query: 204 KAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQ--- 260
++LL + L +LE+ NQ + KA +A LQ + E+E+
Sbjct: 2808 --QQLLSKDEQLLHLSSQLEDSYNQVQSFSKA----MASLQNERDHLWNELEKFRKSEEG 2861
Query: 261 LSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKE 315
R+AA S S E +Q LK M +L D+DR ++EL L QY ++ +
Sbjct: 2862 KQRSAAQPSTSPAE----VQSLKKAMSSL---QNDRDRLLKELKNLQQQYLQINQ 2909
Score = 42.4 bits (98), Expect = 0.002
Identities = 59/269 (21%), Positives = 112/269 (41%), Gaps = 38/269 (14%)
Query: 91 ESLSQVNHHSAASNETYQ---ERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLE 147
+ + Q+ A E Q E LE +K +L+ Q+S +++ E++ + + +
Sbjct: 1840 QQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQ 1899
Query: 148 GHQVKLNAAEEMLQQELLSRTSLETQKLDLMTE-----------VSELKLKLVGMEKEQR 196
Q +L+ ++ + + LE + ++ + E V++ ++K +E E +
Sbjct: 1900 QIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMK 1959
Query: 197 EQEEKQRKAEELLQELRHLKIKVE-ELEN---ERNQYEWKLKATKAEVAQLQEQVALKDA 252
++ + EE Q+L K KVE E+ E+ Q K K+ +LQE + K
Sbjct: 1960 NLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQ 2019
Query: 253 EIERLH----------SQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEE 302
E+++L S L RT TE ++++ K E L A E + + E
Sbjct: 2020 EVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITK---ENLAQAVEHRKKAQAE 2076
Query: 303 LTGLLNQYRKVKEIVMVTQGPSERTLSIN 331
L K ++ TQ + R L+ N
Sbjct: 2077 LASF-------KVLLDDTQSEAARVLADN 2098
Score = 42.0 bits (97), Expect = 0.002
Identities = 69/299 (23%), Positives = 128/299 (42%), Gaps = 34/299 (11%)
Query: 60 ALEMLELPQERAALLSQIP-----GPTAAYIKEWFEESLSQV-NHHSAASNETYQERLAR 113
++E+ EL E L SQI T +E E S+ + N S+++ E+ Q+ L
Sbjct: 491 SIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLEN 550
Query: 114 LEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLE-- 171
K ++SVL +++ E+I L++ L+G + + A E+L Q+ + + E
Sbjct: 551 TFSQKHK---ELSVLLLEMKEAQEEIAFLKLQLQGKRAE-EADHEVLDQKEMKQMEGEGI 606
Query: 172 ---TQKLDLMTEVSELKL------KLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEEL 222
K+ L + L L +EKEQ E + R +EE+ L EL
Sbjct: 607 APIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEI-----SLNDAGVEL 661
Query: 223 ENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRL 282
++ + + L A Q+++ ++I L + ++ ++ E+ +EI L
Sbjct: 662 KSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNL 721
Query: 283 KMGMETLLLANEDKDRRIEELTGLLNQ----YRKVKEIVMVTQGPSE-RTLSINEEEPE 336
+E ++ D T L + +VKE+ MVT+ ++ + L +N E E
Sbjct: 722 NQLIEEF---KKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAE 777
Score = 42.0 bits (97), Expect = 0.002
Identities = 60/258 (23%), Positives = 115/258 (44%), Gaps = 36/258 (13%)
Query: 57 LRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEG 116
L + LE +L QE AA +++ +E + + H N + A L
Sbjct: 2488 LSIILEKDQLIQEAAAENNKL------------KEEIRGLRSHMDDLNSENAKLDAELIQ 2535
Query: 117 DKESLILQVSVLTDQ----VEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLET 172
+E L +++ Q +E Q ++ ++LE + KL +EE + S +L+
Sbjct: 2536 YREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQE 2595
Query: 173 QKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENER-----N 227
+K DL E+ LK+ + + ++ + EE L H ++KV+E E R +
Sbjct: 2596 EKQDLSKEIESLKVSISQLTRQVTALQ------EEGTLGLYHAQLKVKEEEVHRLSALFS 2649
Query: 228 QYEWKLKATKAEVAQLQEQVALKDAEIE-RLHSQLSR----TAALHSESHT--ERDQEIQ 280
+ ++ + E+ +Q++ A K EIE +L +L + +E+ T ER E+
Sbjct: 2650 SSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELA 2709
Query: 281 R--LKMGMETLLLANEDK 296
R ++M + L++ E+K
Sbjct: 2710 RDLVEMEQKLLMVTKENK 2727
Score = 40.4 bits (93), Expect = 0.007
Identities = 52/239 (21%), Positives = 102/239 (42%), Gaps = 31/239 (12%)
Query: 91 ESLSQVNHHSAASNETYQE--RLARLEGDKESLI--LQVSVLTDQVEAQGEKIRDLEVCL 146
+S Q++ H +S E E ++ +KE LI LQ + Q E + ++E +
Sbjct: 127 QSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFV 186
Query: 147 EGHQVKLNAAEEMLQQELLSRTS-LETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKA 205
M++Q+L + + T + L +E + V EK+ R + + +
Sbjct: 187 ------------MMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHE 234
Query: 206 EELLQELRHLKI------KVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHS 259
+ELLQ + + K+ L+ + ++E L V LQ+++ + + L
Sbjct: 235 DELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQ 294
Query: 260 QLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRI------EELTGLLNQYRK 312
QL + A H+ + E + K+ +E + L E +R++ EE+ LL Q+ +
Sbjct: 295 QLQQMEAEHNTLRNTVETEREESKILLEKMEL--EVAERKLSFHNLQEEMHHLLEQFEQ 351
Score = 40.4 bits (93), Expect = 0.007
Identities = 49/217 (22%), Positives = 91/217 (41%), Gaps = 20/217 (9%)
Query: 90 EESLSQVNHHSAASNETYQERLARLEGD---KESLILQVSVLTDQVEAQGEKIRDLEVCL 146
+ LSQ AA + +E+ AR E E +LQ+ D +K+R L+ L
Sbjct: 203 QAQLSQTQAEQAAQ-QVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKL 261
Query: 147 EGHQVKLNAAEE---MLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQR 203
E H+ L + +LQQEL T+ E + L ++ +++ + R E +R
Sbjct: 262 EEHEESLVGRAQVVDLLQQEL---TAAEQRNQILSQQLQQMEAE----HNTLRNTVETER 314
Query: 204 KAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSR 263
+ ++L E L++ +L Q E + + EQ AE+E +S L +
Sbjct: 315 EESKILLEKMELEVAERKLSFHNLQEEMH------HLLEQFEQAGQAQAELESRYSALEQ 368
Query: 264 TAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRI 300
E T +Q+ +++ A +D++ ++
Sbjct: 369 KHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKL 405
Score = 40.0 bits (92), Expect = 0.009
Identities = 61/245 (24%), Positives = 100/245 (40%), Gaps = 29/245 (11%)
Query: 60 ALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKE 119
A E+ EL +E+ + Q+ Y +E +S + A E LE KE
Sbjct: 2007 AKELQELLKEKQQEVKQLQKDCIRY-----QEKISALERTVKALEFVQTESQKDLEITKE 2061
Query: 120 SLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMT 179
+L V + +AQ E + +V L+ Q + A +L L + L++ K +
Sbjct: 2062 NLAQAVE---HRKKAQAE-LASFKVLLDDTQ---SEAARVLADNLKLKKELQSNKESVK- 2113
Query: 180 EVSELKLKLVGMEKEQREQEEKQRKAEELLQE----LRHLKIKVEELENERNQYEWKLKA 235
S++K K +E+ + EEK K ++ +QE LR K+ +EE E + L
Sbjct: 2114 --SQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGE---IQVTLNK 2168
Query: 236 TKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANED 295
EV QLQE ++ +QL+ S +RD+ I K A +
Sbjct: 2169 KDKEVQQLQE-------NLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQS 2221
Query: 296 KDRRI 300
K+ I
Sbjct: 2222 KEEEI 2226
Score = 38.9 bits (89), Expect = 0.021
Identities = 56/266 (21%), Positives = 117/266 (43%), Gaps = 9/266 (3%)
Query: 54 IEDLRLALEMLE----LPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQE 109
+E+L++ + LE + + +A Q+ ++ +E LSQ+ + + Q
Sbjct: 2247 MEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSS-QN 2305
Query: 110 RLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAE---EMLQQELLS 166
LA+LE + +SL Q++ L++ +E E+ +LE + + + ++ E L+ +L +
Sbjct: 2306 ELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQA 2365
Query: 167 RTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENER 226
L T +L + E K+ + KE+ Q ++ +E++ L+ + + E E
Sbjct: 2366 SREL-TSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEEN 2424
Query: 227 NQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGM 286
E + K + QL E + E + +QL S +RD+ + +
Sbjct: 2425 IVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE 2484
Query: 287 ETLLLANEDKDRRIEELTGLLNQYRK 312
E L +KD+ I+E N+ ++
Sbjct: 2485 ERHLSIILEKDQLIQEAAAENNKLKE 2510
Score = 37.0 bits (84), Expect = 0.080
Identities = 49/249 (19%), Positives = 107/249 (42%), Gaps = 48/249 (19%)
Query: 109 ERLARLEGDKESLILQVSVLTDQVEA-QGEKIRDLEVCLEGHQV---KLNAAEEMLQQEL 164
+ + +L+ + +S + Q++ T + + Q ++ R ++ + + + + EE ++ +
Sbjct: 2171 KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKE 2230
Query: 165 LSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEK---------------QRKAEELL 209
+ + L+ Q + + ELK+ + +E +++ E K Q + +ELL
Sbjct: 2231 DNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELL 2290
Query: 210 QELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQ--------------VALKDAEI- 254
+L + +NE + E +LK+ K ++ L + ++A+I
Sbjct: 2291 SQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQ 2350
Query: 255 ------ERLHSQLSRTAALHSESHTE---RDQEIQRLKMGMETLLLA-----NEDKDRRI 300
E+L + L + L S H E ++Q+I L G E + + D+ I
Sbjct: 2351 NSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEI 2410
Query: 301 EELTGLLNQ 309
+EL LL+Q
Sbjct: 2411 KELENLLSQ 2419
Score = 36.6 bits (83), Expect = 0.10
Identities = 42/197 (21%), Positives = 90/197 (45%), Gaps = 15/197 (7%)
Query: 100 SAASNETYQERLARLEGDKESLILQVSVLTDQ---VEAQGEKIRDLEVCLEGHQVKLNAA 156
S A ++ ++ ++ L+ D++ L+ ++ L Q + + ++ L+ L+ +Q K A
Sbjct: 2872 SPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAF 2931
Query: 157 EEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKA-EELLQELRHL 215
+ M ++ L + L E+ +L+++ E +R +E+ A + Q+L HL
Sbjct: 2932 QIMQEE-------LRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHL 2984
Query: 216 KIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHS--ESHT 273
+ + EL + +Q + LK A + + ++ ++L RT S E H
Sbjct: 2985 QNLIRELRSSSSQTQ-PLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIH- 3042
Query: 274 ERDQEIQRLKMGMETLL 290
+++ IQ+L LL
Sbjct: 3043 QKELRIQQLNSNFSQLL 3059
Score = 35.4 bits (80), Expect = 0.23
Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 6/79 (7%)
Query: 183 ELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQ 242
EL+ K++ +EKE+ E+ Q+K +E L + + K +E E + +LK K + +
Sbjct: 1161 ELEEKILALEKEK---EQLQKKLQEALTSRKAILKKAQEKERHLRE---ELKQQKDDYNR 1214
Query: 243 LQEQVALKDAEIERLHSQL 261
LQEQ + E E + QL
Sbjct: 1215 LQEQFDEQSKENENIGDQL 1233
Score = 32.3 bits (72), Expect = 2.0
Identities = 42/193 (21%), Positives = 78/193 (40%), Gaps = 32/193 (16%)
Query: 90 EESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGH 149
+E + + N S+ + Y E + KE L + +L + E + K+
Sbjct: 946 KEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKL---------- 995
Query: 150 QVKLNAAEEMLQQELLSRTSLETQKLDLMTEV--SELKLKLVGMEKEQREQEEK------ 201
Q L +E+LQ+ L K + E+ SE + V +KE +E EK
Sbjct: 996 QAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKC 1055
Query: 202 -------QRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEI 254
++ E EL+H++ +EE Q++ A V Q+ + + K +I
Sbjct: 1056 QEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQ-------ALVKQMNQTLQDKTNQI 1108
Query: 255 ERLHSQLSRTAAL 267
+ L +++S A+
Sbjct: 1109 DLLQAEISENQAI 1121
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 60.8 bits (146), Expect = 5e-09
Identities = 105/459 (22%), Positives = 177/459 (38%), Gaps = 83/459 (18%)
Query: 10 EAALEQMDGII---AGTKTGADLSDGTCEPGLASPASYMN-PFPVLHLIEDLRLALE-ML 64
+ AL ++D + A + A++S E L SP S P+ + + L LA++ ++
Sbjct: 1212 DVALPELDRTLSECAEMSSVAEISSHMRESFLMSPESVRECEQPIRRVFQSLSLAVDGLM 1271
Query: 65 ELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGD---KESL 121
E+ + + L + A I FE+ S N +A +QE L L+ + K L
Sbjct: 1272 EMALDSSRQLEE-----ARQIHSRFEKEFSFKNEETAQVVRKHQELLECLKEESAAKAEL 1326
Query: 122 ILQVSVLTDQVEAQGEKIRDLEVCLEGHQ-------VKLNAAEEMLQQELLSRTSL---- 170
L++ +E + DL+ L G + ++L + LQQ + +L
Sbjct: 1327 ALELHKTQGTLEGFKVETADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREEC 1386
Query: 171 -------ETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELE 223
E D + L+ ++ + KEQ E ++ K L L +KI ELE
Sbjct: 1387 TRLWSRGEATATDAEAREAALRKEVEDLTKEQSETRKQAEKDRSAL--LSQMKILESELE 1444
Query: 224 NERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLK 283
+ +Q+ K +A V L++QVA D + + AA E QEIQRL+
Sbjct: 1445 EQLSQHRGCAKQAEA-VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLE 1503
Query: 284 ---------------------MGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQG 322
+ E LL + ++ +++E L Q V++ +
Sbjct: 1504 GQLRQAAKPQPWGPRDSQQAPLDGEVELLQQKLRE-KLDEFNELAIQKESADRQVLMQEE 1562
Query: 323 PSERTLSIN----------EEEPEGGFSKWNATNKDPEELFKQEMPP------------- 359
+R +N +EE E + +D E L KQ+M
Sbjct: 1563 EIKRLEEMNINIRKKVAQLQEEVEKQKNIVKGLEQDKEVLKKQQMSSLLLASTLQSTLDA 1622
Query: 360 -RCSSPTVGPPPL-PQKSLET--RAQKKLSCSLEDLRSE 394
RC P G PP P+ LE RA + + DL+ +
Sbjct: 1623 GRCPEPPSGSPPEGPEIQLEVTQRALLRRESEVLDLKEQ 1661
Score = 45.4 bits (106), Expect = 2e-04
Identities = 58/218 (26%), Positives = 101/218 (46%), Gaps = 24/218 (11%)
Query: 105 ETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEG---HQVKLNAAEEMLQ 161
E ER AR+ G + +Q+S+L +++ + E ++ L G H+ +L E ++
Sbjct: 661 EADTERAARVLGLETEHKVQLSLLQTELKEEIELLKIENRNLYGKLQHETRLKDDLEKVK 720
Query: 162 QELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQRE-QEEKQRKAEELLQELRHLKIKVE 220
L+ E TE+ +K + E + + +EE QR+AEE L L L+++ E
Sbjct: 721 HNLIEDHQKELNNAKQKTEL--MKQEFQRKETDWKVMKEELQREAEEKLT-LMLLELR-E 776
Query: 221 ELENERNQYEWKLKATKAEVAQLQEQVALKDAEIER-----------LHSQLSRTAALH- 268
+ E+E+ K + +AE+ QLQ+Q A + ++ER L L+ ALH
Sbjct: 777 KAESEKQTIINKFELREAEMRQLQDQQAAQILDLERSLTEQQGRLQQLEQDLTSDDALHC 836
Query: 269 ----SESHTERDQEIQRLKMGMETLLLANEDKDRRIEE 302
E T +D E+ L + + L + R +EE
Sbjct: 837 SQCGREPPTAQDGELAALHVKEDCALQLMLARSRFLEE 874
Score = 43.1 bits (100), Expect = 0.001
Identities = 71/292 (24%), Positives = 121/292 (41%), Gaps = 56/292 (19%)
Query: 60 ALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKE 119
+LE L LP +R++LLS+I A ++ ++ ++ H A AR +
Sbjct: 2505 SLEHLRLP-DRSSLLSEIQA-LRAQLRMTHLQNQEKLQHLRTALTSAE----ARGSQQEH 2558
Query: 120 SLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMT 179
L QV +L +VE + DL+ L Q K N+ +++L E T
Sbjct: 2559 QLRRQVELLAYKVEQEKCIAGDLQKTLSEEQEKANSVQKLLAAE--------------QT 2604
Query: 180 EVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAE 239
V +LK L E ++K+E+L + L ++ +V +L + + E +LKA E
Sbjct: 2605 VVRDLKSDLC----------ESRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQE 2654
Query: 240 VAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMET-------LLLA 292
+ Q + L SQL H + ++ + ++ L+ +ET L +A
Sbjct: 2655 LESEQ-------GKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQRAQSSRLCVA 2707
Query: 293 ---------NEDKDRRIE--ELTGLLNQYR-KVKEIVMVTQGPSERTLSINE 332
N K+ RIE LL Q R ++ E+ RTL ++E
Sbjct: 2708 LKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQKDLAAEKSRTLELSE 2759
Score = 42.7 bits (99), Expect = 0.001
Identities = 68/309 (22%), Positives = 122/309 (39%), Gaps = 17/309 (5%)
Query: 58 RLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGD 117
+L+ + E+ QE L S + +K +E S+ A ++ +E+L L+ +
Sbjct: 2622 QLSRSLCEVQQEVLQLRSMLSSKENE-LKAALQELESEQGKGRALQSQLEEEQLRHLQRE 2680
Query: 118 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQEL-LSRTSLETQKLD 176
+S + L +E Q + L V L+ Q A++ LQ+EL + + E
Sbjct: 2681 SQSA-KALEELRASLETQRAQSSRLCVALKHEQT----AKDNLQKELRIEHSRCEALLAQ 2735
Query: 177 LMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQEL--RHLKIKVEELENERNQYEWKLK 234
+++SEL+ L + E E R L ++L R + V + + KLK
Sbjct: 2736 ERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAHHALLQKLK 2795
Query: 235 ATKAEVAQLQEQVALKDAEIERLHS--QLSRTAALHSESHTERDQEIQRLKMGMETLLLA 292
K+ V L Q L+ + + LHS QL A H E+ + LK +E L
Sbjct: 2796 EEKSRVVDL--QAMLEKVQQQALHSQQQLEAEAQKHCEALRREKEVSATLKSTVEALHTQ 2853
Query: 293 NED----KDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKD 348
+ +R E+ L + + + +G S + +W +D
Sbjct: 2854 KRELRCSLEREREKPAWLQAELEQSHPRLKEQEGRKAARRSAEARQSPAAAEQWRKWQRD 2913
Query: 349 PEELFKQEM 357
E+L + E+
Sbjct: 2914 KEKLRELEL 2922
Score = 38.5 bits (88), Expect = 0.028
Identities = 68/274 (24%), Positives = 119/274 (43%), Gaps = 48/274 (17%)
Query: 55 EDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARL 114
++ LA+ LE +E A L Q A + E LS N H+A T A L
Sbjct: 217 QECELAITDLESGREDEAGLHQ---SQAVHGLELEALRLSLSNMHTAQLELTQ----ANL 269
Query: 115 EGDKESLILQVSVLTDQVEAQ------GEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRT 168
+ +KE+ + ++ + + AQ + +LE+ E H A E ++E++ R
Sbjct: 270 QKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQH------ARE--KEEVVLRC 321
Query: 169 SLETQKL-DLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQEL--RHLKIKVEELENE 225
E +L + + E ++V KE E E K E L +EL +H E+E+
Sbjct: 322 GQEAAELKEKLQSEMEKNAQIVKTLKEDWESE-KDLCLENLRKELSAKHQS----EMEDL 376
Query: 226 RNQYEWKLKATKAEVAQL-----QEQVALKDAE------IERLHSQLSRTAA-------- 266
+NQ++ +L +AE+ ++ Q + AL++ E IE+L L
Sbjct: 377 QNQFQKELAEQRAELEKIFQDKNQAERALRNLESHHQAAIEKLREDLQSEHGRCLEDLEF 436
Query: 267 LHSESHTERDQEIQRLKMGMETLLLANEDKDRRI 300
ES E+ E++ L+ E L ++++ RR+
Sbjct: 437 KFKESEKEKQLELENLQASYEDLKAQSQEEIRRL 470
Score = 38.1 bits (87), Expect = 0.036
Identities = 53/247 (21%), Positives = 111/247 (44%), Gaps = 30/247 (12%)
Query: 105 ETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQEL 164
E Q L R E + L Q+ + +E++ E+I L + L+ + + L++E
Sbjct: 1642 EVTQRALLRRESEVLDLKEQLEKMKGDLESKNEEILHLNLKLDMQNSQTAVSLRELEEEN 1701
Query: 165 LSRTSLETQKLDLMTEVSELKLKLVGMEKEQRE-QEEKQRKAEEL---LQELRHL----- 215
S + T+ +E+ ELK + +++ Q+ Q+EK + E+L +++L+H
Sbjct: 1702 TSLKVIYTRS----SEIEELKATIENLQENQKRLQKEKAEEIEQLHEVIEKLQHELSLMG 1757
Query: 216 KIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTER 275
+ E +++ + +L ++A + Q +A +E + LSR A H++
Sbjct: 1758 PVVHEVSDSQAGSLQSELLCSQAGGPRGQALQGELEAALEAKEA-LSRLLADQERRHSQA 1816
Query: 276 DQEIQRLKMGME---TLLLANED-----KDRRIEELTGLLNQYR---KVKEIVMVTQGPS 324
+ +Q+ G E L LA + ++ +E++ + ++ K KE + +
Sbjct: 1817 LEALQQRLQGAEEAAELQLAELERNVALREAEVEDMASRIQEFEAALKAKEATI-----A 1871
Query: 325 ERTLSIN 331
ER L I+
Sbjct: 1872 ERNLEID 1878
Score = 31.2 bits (69), Expect = 4.4
Identities = 52/214 (24%), Positives = 91/214 (42%), Gaps = 43/214 (20%)
Query: 133 EAQGEKIRDLEVCLEGHQVKL---NAAEEMLQQELLSR--TSLETQKLDLM-TEVSELKL 186
EAQ + R+L++ E HQ +L A E Q L SLE+++ L+ V+EL+
Sbjct: 892 EAQEQHARELQLLQERHQQQLLSVTAELEARHQAALGELTASLESKQGALLAARVAELQT 951
Query: 187 K----LVGME---------------KEQREQEEKQRKAEELL----------QELRHLKI 217
K L +E E + E+ R+A ELL ++ H I
Sbjct: 952 KHAADLGALETRHLSSLDSLESCYLSEFQTIREEHRQALELLRADFEEQLWKKDSLHQTI 1011
Query: 218 KVEELENERNQYEWKLKATKAEV-----AQLQEQVALKDAEIERLHSQLSRTAALHSESH 272
+ELE + ++E +L++ + + +L VA + + + + ALH +
Sbjct: 1012 LTQELEKLKRKHEGELQSVRDHLRTEVSTELAGTVAHELQGVHQGEFGSEKKTALHEKEE 1071
Query: 273 TERDQEIQRLKMGM---ETLLLANEDKDRRIEEL 303
T R Q Q E+L L + K+ ++++L
Sbjct: 1072 TLRLQSAQAQPFHQEEKESLSLQLQKKNHQVQQL 1105
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 60.8 bits (146), Expect = 5e-09
Identities = 65/288 (22%), Positives = 137/288 (47%), Gaps = 29/288 (10%)
Query: 54 IEDLRLALEMLELP----QERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQE 109
+E++ L+ ++ E +E+ + +Q+ G A + + E + Q+ E Q
Sbjct: 615 LENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQ--EAAFMQIQEAKTMVEEDLQR 672
Query: 110 RLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEE----MLQQELL 165
RL EG++E L + D + +++ +++ L +L A ++ +++Q L
Sbjct: 673 RLEEFEGERERL----QRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTL 728
Query: 166 SRTSLET--QKLD-LMTEVSELKLKLVGMEKEQREQEEK----QRKAEELLQELRHLKIK 218
++ +L++ Q LD L T EL+ +L ++ E +E+ Q + L L+ K
Sbjct: 729 TQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSG 788
Query: 219 VEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQE 278
EEL+ + E + T + +L+E++A+K ++E L + TAAL + ++Q
Sbjct: 789 KEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQE---TAALKKQMQKIKEQF 845
Query: 279 IQRLKMGMETLLLANEDKDRRIEELTG----LLNQYRKVKEIVMVTQG 322
+Q+ K+ +E KD+ I EL L ++ +++++ +M G
Sbjct: 846 LQQ-KVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHG 892
Score = 58.9 bits (141), Expect = 2e-08
Identities = 72/321 (22%), Positives = 134/321 (41%), Gaps = 25/321 (7%)
Query: 93 LSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEK----IRDLEVCLEG 148
L Q N N + LA+ E D L LQV + + E + + ++ L+ LE
Sbjct: 1124 LGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEK 1183
Query: 149 HQVKLNAAEEMLQQELL----SRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQ-- 202
+ K+N+ +E + + +R + L+L EL+ K ++K Q E ++ Q
Sbjct: 1184 EKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIR 1243
Query: 203 --RKAEELLQ---ELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERL 257
+ ++E+ Q EL + +++ L+ + ++ K E+ L+ +V K+ EI+ L
Sbjct: 1244 EGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSL 1303
Query: 258 HSQLSRTAALHSESHTERDQEIQRLK----MGMETLLLANEDKDRRIEELTGLLNQYRKV 313
QL T + Q +Q +K M E L + +DK +++ L N + +
Sbjct: 1304 KQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNMKTL 1363
Query: 314 KEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQ 373
+ + R + +EP+G S N P ++ +P + PPP
Sbjct: 1364 LQQNQQLKLDLRRGAAKTRKEPKGEASSSNPAT--PIKIPDCPVPASLLEELLRPPPAVS 1421
Query: 374 KSLETRAQKKLSCSLEDLRSE 394
K K L+ L+ L+ E
Sbjct: 1422 K----EPLKNLNSCLQQLKQE 1438
Score = 52.8 bits (125), Expect = 1e-06
Identities = 61/311 (19%), Positives = 138/311 (44%), Gaps = 24/311 (7%)
Query: 93 LSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVK 152
L + ++ + E +E LA G E L + + L Q++ E+ +V +E ++
Sbjct: 799 LEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRD 858
Query: 153 LNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEK----QRKAEEL 208
+ ++++ + +R L+ +E+ EL+ +L+ + E+R E + R+ ++
Sbjct: 859 ATSKDQLISELKATRKRLD-------SELKELRQELMQVHGEKRTAEAELSRLHREVAQV 911
Query: 209 LQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALH 268
Q + L+ ++ + ER++ E L++ + + Q+ VA+ +A E L Q+
Sbjct: 912 RQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQM---VAVTEAN-EALKKQIEELQQEA 967
Query: 269 SESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTL 328
++ TE+ Q+++RL + + + K + E G+L+ R+++E + +
Sbjct: 968 RKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILS--RRLQEALAAKEAAD---A 1022
Query: 329 SINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQ----KSLETRAQKKL 384
+ + +GG S + + + + E+ S T+ L + S E ++
Sbjct: 1023 ELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREK 1082
Query: 385 SCSLEDLRSES 395
LED ES
Sbjct: 1083 VLELEDELQES 1093
Score = 46.2 bits (108), Expect = 1e-04
Identities = 62/260 (23%), Positives = 108/260 (41%), Gaps = 55/260 (21%)
Query: 94 SQVNHHSAASNETYQERLA------RLEGDKESLILQVS-VLTDQVEAQGE------KIR 140
S V+ S+A+ ET +E L RLEG E+L L+ S L ++ E Q + K++
Sbjct: 392 SSVSLESSAA-ETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQ 450
Query: 141 DLEVCLEGHQVK-----------------LNAAEEMLQQELLSRT-SLETQKLDLMTEVS 182
C Q + L A LQ L ++ SL + DL
Sbjct: 451 AQVECSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEE 510
Query: 183 ELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQ 242
+ + + +E QR K +L Q++ L+ ++++++ ER KLKA++AE++
Sbjct: 511 QYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISS 570
Query: 243 LQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMG-------METLLLANED 295
LQ + + AL E+ E+ +++G +E L L N
Sbjct: 571 LQS-----------VRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVS 619
Query: 296 KDRRIEELTGLLNQYRKVKE 315
+++ E Q+R +KE
Sbjct: 620 LSQQLTE-----TQHRSMKE 634
Score = 35.8 bits (81), Expect = 0.18
Identities = 58/296 (19%), Positives = 113/296 (38%), Gaps = 71/296 (23%)
Query: 92 SLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQV 151
SL+ N+ + E YQ +A++E + S++ ++ + DL +
Sbjct: 497 SLASSNNDLQVAEEQYQRLMAKVEDMQRSML-----------SKDNTVHDL-------RQ 538
Query: 152 KLNAAEEMLQQELLSRTSLETQKLDLMTEVSELK---------LKLVGMEKEQREQEEKQ 202
++ A + LQQ L RT+L ++ E+S L+ L L + + + E
Sbjct: 539 QMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAH 598
Query: 203 RKAEELLQE--LRHLKIKVEELENERNQYEWKLKATKAEVA------------------- 241
+ ++ Q L HLK++ L + + + + K +A
Sbjct: 599 IQVGQMTQAGLLEHLKLENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQ 658
Query: 242 ----------QLQEQVALKDAEIERLHSQLSRTAALHSE------SHTERDQEIQRLKMG 285
LQ ++ + E ERL A+L + + +RDQ+++ L+
Sbjct: 659 IQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQE 718
Query: 286 ----METLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPS---ERTLSINEEE 334
M+ L L E R + L L Y +++ + QG + E T+ + + E
Sbjct: 719 HLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNE 774
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 60.1 bits (144), Expect = 9e-09
Identities = 46/194 (23%), Positives = 90/194 (46%), Gaps = 7/194 (3%)
Query: 90 EESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGH 149
EE + VN A+ +T Q RL+G+ E L++ V A +K R+ + L
Sbjct: 1402 EEQVEAVNAKCASLEKTKQ----RLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEW 1457
Query: 150 QVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELL 209
+ K ++ L+ L SL T+ L E L +E +RE + +++ +L
Sbjct: 1458 KTKCEESQAELEASLKESRSLSTELFKLKNAYEEA---LDQLETVKRENKNLEQEIADLT 1514
Query: 210 QELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHS 269
+++ + ELE R Q E + + + + + + ++A+I R+ +L++ +
Sbjct: 1515 EQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEID 1574
Query: 270 ESHTERDQEIQRLK 283
E+D+EI++LK
Sbjct: 1575 RKIAEKDEEIEQLK 1588
Score = 54.7 bits (130), Expect = 4e-07
Identities = 54/232 (23%), Positives = 100/232 (43%), Gaps = 12/232 (5%)
Query: 83 AYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL 142
A +KE F+++ ++ S A + +E+L L +K L LQV ++ + E+ L
Sbjct: 851 ATMKEEFQKTKDELAK-SEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQL 909
Query: 143 EVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGME----KEQREQ 198
+ K+ E + E L +K L E SELK + +E K ++E+
Sbjct: 910 IKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 969
Query: 199 EEKQRKAEELLQELRHLKIKVEELENERNQYEW-------KLKATKAEVAQLQEQVALKD 251
+ K + L +EL L + +L E+ + L+A + +V L + + +
Sbjct: 970 HATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLE 1029
Query: 252 AEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEEL 303
++E L S L + L + + + LK+ E++L DK + E L
Sbjct: 1030 QQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERL 1081
Score = 54.3 bits (129), Expect = 5e-07
Identities = 47/207 (22%), Positives = 94/207 (45%), Gaps = 7/207 (3%)
Query: 113 RLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLET 172
+LE +K L++ L+ +E+ + +LE + +L+ A ++ S + L T
Sbjct: 1217 KLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTT 1276
Query: 173 QKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWK 232
QK L TE EL +L E+++ + R + Q+ LK ++EE +N
Sbjct: 1277 QKSRLQTEAGELSRQL---EEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHA 1333
Query: 233 LKATKAEVAQLQEQVALKD---AEIERLHSQL-SRTAALHSESHTERDQEIQRLKMGMET 288
L++++ + L+EQ + AE++R S+ S A ++ T+ Q + L+ +
Sbjct: 1334 LQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1393
Query: 289 LLLANEDKDRRIEELTGLLNQYRKVKE 315
L +D + ++E + K K+
Sbjct: 1394 LAQRLQDSEEQVEAVNAKCASLEKTKQ 1420
Score = 51.2 bits (121), Expect = 4e-06
Identities = 59/239 (24%), Positives = 107/239 (44%), Gaps = 37/239 (15%)
Query: 111 LARLEGDKESLILQVSVLTDQVEAQGEKI----RDLEVCLEGHQVKLN---AAEEMLQQE 163
LA++E +K + +V LT+++ E I R+ + E HQ L+ A E+ +
Sbjct: 962 LAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSL 1021
Query: 164 LLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELE 223
+++ LE Q DL + + + K V +E+ +R+ E + A+E + +LE
Sbjct: 1022 NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQE----------SILDLE 1071
Query: 224 NERNQYEWKLKATKAEVAQLQEQV------------ALKD--AEIERLHSQLSRTAALHS 269
N++ Q + +LK E QLQ +V +K+ A IE L ++ A +
Sbjct: 1072 NDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRA 1131
Query: 270 ESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTL 328
++ +R + L+ E L A +IE LN+ R+ E + + + E TL
Sbjct: 1132 KTEKQRSDYARELEELSERLEEAGGVTSTQIE-----LNKKREA-EFLKLRRDLEEATL 1184
Score = 42.4 bits (98), Expect = 0.002
Identities = 56/238 (23%), Positives = 94/238 (39%), Gaps = 22/238 (9%)
Query: 108 QERLARLEGDKESLI-------LQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEML 160
QE + LE DK+ L + L +VE + + ++ Q ++ EE +
Sbjct: 1064 QESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEI 1123
Query: 161 QQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVE 220
+ E +R E Q+ D E+ EL +L Q E +K E +LR
Sbjct: 1124 EAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRR------ 1177
Query: 221 ELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQ 280
+LE Q+E A VA L+++ A AE+ L R + +E EI
Sbjct: 1178 DLEEATLQHE-------AMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEID 1230
Query: 281 RLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGG 338
L ME++ + + ++ L L++ R E + + SE T + + E G
Sbjct: 1231 DLSSSMESVSKSKANLEKICRTLEDQLSEARGKNE--EIQRSLSELTTQKSRLQTEAG 1286
Score = 42.4 bits (98), Expect = 0.002
Identities = 88/411 (21%), Positives = 158/411 (38%), Gaps = 81/411 (19%)
Query: 2 ASDASHALEAALEQMDGIIAGTKTGADLSDGTCEPGLASPASYMNP-FPVLHLIEDLRLA 60
A+ + AL+ D ++A KT + S E L S F + + E+
Sbjct: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQ 1495
Query: 61 LEMLE-----LPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLE 115
LE ++ L QE A L QI I E E+S Q+ A +E A LE
Sbjct: 1496 LETVKRENKNLEQEIADLTEQI-AENGKTIHE-LEKSRKQIELEKADIQLALEEAEAALE 1553
Query: 116 GDKESLILQVSVLTDQVEAQ-----GEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSL 170
+ E+ IL++ + QV+++ EK ++E +Q + + L E+ SR
Sbjct: 1554 HE-EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEA 1612
Query: 171 ETQKLDLMTEVSELKLKLVGMEKEQRE-------------------------QEEK---- 201
K + +++E++++L ++ E QE+
Sbjct: 1613 IRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQL 1672
Query: 202 ---QRKAEELLQELRHLKIKVEELENERNQYEWKL---------------------KATK 237
+R+A L E+ L+ +E+ E R E +L K +
Sbjct: 1673 AIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLE 1732
Query: 238 AEVAQLQEQV--ALKDAE--IERLHSQLSRTAALHSESHTERD--QEIQRLKMGMETLLL 291
++ QLQ +V A +DA E+ ++ A + E E+D ++R+K +E +
Sbjct: 1733 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV- 1791
Query: 292 ANEDKDRRIEE-----LTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEG 337
+D R++E L G Q +K++ + + E N E +G
Sbjct: 1792 --KDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKG 1840
Score = 40.8 bits (94), Expect = 0.006
Identities = 70/308 (22%), Positives = 126/308 (40%), Gaps = 33/308 (10%)
Query: 58 RLALEMLELP---QERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASN---------- 104
RL E EL +E+ +++SQ+ A+ ++ EE Q+ + A N
Sbjct: 1280 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQT-EELKRQLEEENKAKNALAHALQSSR 1338
Query: 105 ----------ETYQERLARLEGDKESLILQVSVLTDQVEAQG-EKIRDLEVCLEGHQVKL 153
E QE A L+ +V+ + E ++ +LE + +L
Sbjct: 1339 HDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1398
Query: 154 NAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELR 213
+EE ++ SLE K L EV +L + + ++KQR +++L E
Sbjct: 1399 QDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAE-- 1456
Query: 214 HLKIKVEELENERNQYEWKLKATKAEVAQLQE--QVALKDAE-IERLHSQLSRTAALHSE 270
K K EE + E + ++ E+ +L+ + AL E ++R + L + A +E
Sbjct: 1457 -WKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTE 1515
Query: 271 SHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLL-NQYRKVKEIVM-VTQGPSERTL 328
E + I L+ + + L D +EE L ++ K+ I + +TQ SE
Sbjct: 1516 QIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDR 1575
Query: 329 SINEEEPE 336
I E++ E
Sbjct: 1576 KIAEKDEE 1583
Score = 39.3 bits (90), Expect = 0.016
Identities = 45/226 (19%), Positives = 99/226 (43%), Gaps = 34/226 (15%)
Query: 118 KESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLS----------- 166
+E L Q++++ + ++ +L LE + A ++ +QELL
Sbjct: 1665 QEDLKEQLAIVERRANLLQAEVEELRATLE----QTERARKLAEQELLDSNERVQLLHTQ 1720
Query: 167 RTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENER 226
TSL K L T++ +L+ ++ ++ R EEK +KA + + EEL+ E+
Sbjct: 1721 NTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKA------ITDAAMMAEELKKEQ 1774
Query: 227 NQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGM 286
+ T A + ++++ + + ++ L +L L + ++ Q+++ +
Sbjct: 1775 D--------TSAHLERMKKNL---EQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIREL 1823
Query: 287 ETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINE 332
E L + K+ E + GL R+VKE+ ++ + L + +
Sbjct: 1824 EFELEGEQKKN--TESVKGLRKYERRVKELTYQSEEDRKNVLRLQD 1867
Score = 33.5 bits (75), Expect = 0.89
Identities = 36/180 (20%), Positives = 72/180 (40%), Gaps = 15/180 (8%)
Query: 90 EESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGH 149
E+ LS+ NE Q L+ L K L + L+ Q+E + + L +
Sbjct: 1254 EDQLSEAR----GKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAF 1309
Query: 150 QVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELL 209
+ + L++E ++ +L L + + L E+EQ + E QR +
Sbjct: 1310 TQQTEELKRQLEEENKAKNALAHA---LQSSRHDCDLLREQYEEEQEGKAELQRALSKAN 1366
Query: 210 QELRHLKIK--------VEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQL 261
E+ + K EELE + + +L+ ++ +V + + A + +RL ++
Sbjct: 1367 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEV 1426
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 60.1 bits (144), Expect = 9e-09
Identities = 78/352 (22%), Positives = 147/352 (41%), Gaps = 25/352 (7%)
Query: 64 LELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNE--TYQERLARLEGDKESL 121
++L ++ A+L SQ+ T ++E + L+ E + Q++L K++L
Sbjct: 1304 IKLAKDVASLSSQLQD-TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1362
Query: 122 ILQVSVLTDQVEAQGEKIRDLEVCLEG-------HQVKLNAAEEMLQQELLSRTSLETQK 174
+S L Q+ +K++D +E Q ++ + +++ + LE K
Sbjct: 1363 ERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 1422
Query: 175 LDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLK 234
L E+ +L + L + E+KQRK ++LL E +++ K + E +R + E + K
Sbjct: 1423 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD-ERDRAEAEAREK 1481
Query: 235 ATKA-EVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLAN 293
TKA +A+ E+ E+ER + L S + + + L+ L
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Query: 294 EDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSK-WNATNKDPEEL 352
E+ ++EEL L K L +N + +G F + A ++ EE
Sbjct: 1542 EEMKTQLEELEDELQATEDAK-----------LRLEVNMQALKGQFERDLQARDEQNEEK 1590
Query: 353 FKQEMPPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQ 404
+Q T Q++L A+KKL L+DL ++ D + G +
Sbjct: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGRE 1641
Score = 50.4 bits (119), Expect = 7e-06
Identities = 52/215 (24%), Positives = 106/215 (49%), Gaps = 17/215 (7%)
Query: 86 KEWFEESLSQVNHHSAASNET--YQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL- 142
+E EE S ++ +A +E + R+A+LE + E + ++D+V ++ L
Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1770
Query: 143 -EVCLEGHQVKLN--AAEEMLQQELLSRTSLETQ----KLDLMTEVSELKLKLVGMEKE- 194
E+ E + N A +++ +Q R+ L K + ++ L+ K+ +E++
Sbjct: 1771 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1830
Query: 195 QREQEEKQRKAEELLQELRHLKIKVEELENERN---QYEWKLKATKAEVAQLQEQVALKD 251
++E EKQ + L Q+ + LK + ++E+ER QY+ + + A V QL+ Q+ +
Sbjct: 1831 EQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1890
Query: 252 AEIERLHS---QLSRTAALHSESHTERDQEIQRLK 283
E +R+++ +L R +ES+ +E+ LK
Sbjct: 1891 EESQRINANRRKLQRELDEATESNEAMGREVNALK 1925
Score = 48.5 bits (114), Expect = 3e-05
Identities = 52/276 (18%), Positives = 123/276 (44%), Gaps = 49/276 (17%)
Query: 62 EMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESL 121
E+ EL Q+ + L + K +E L Q A E + RLA + + E +
Sbjct: 874 ELKELEQKHSQLTEE---------KNLLQEQL-QAETELYAEAEEMRVRLAAKKQELEEI 923
Query: 122 ILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEV 181
+ ++ ++ E +G++++ + + L EE L++E +R L+ +K+ ++
Sbjct: 924 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDL---EEQLEEEEAARQKLQLEKVTAEAKI 980
Query: 182 SELKLKLVGME-------KEQR--------------EQEEKQRKAEELLQE----LRHLK 216
+L+ +++ M+ KE++ E+EEK + +L + + L+
Sbjct: 981 KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1040
Query: 217 IKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERD 276
+++++ E R + E + + + + EQ+A A+I L QL++ ++
Sbjct: 1041 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK-----------KE 1089
Query: 277 QEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRK 312
+E+Q ++ + + ++I EL G ++ ++
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Score = 43.9 bits (102), Expect = 7e-04
Identities = 34/132 (25%), Positives = 69/132 (52%), Gaps = 13/132 (9%)
Query: 174 KLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKL 233
K+ + +V+ + ++ E E ++ +E+Q+KAE EL+ L+ K +L E+N + +L
Sbjct: 840 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAEN---ELKELEQKHSQLTEEKNLLQEQL 896
Query: 234 KATK---AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLL 290
+A AE +++ ++A K E+E + ++ A L E + + +R KM + L
Sbjct: 897 QAETELYAEAEEMRVRLAAKKQELEEILHEME--ARLEEEEDRGQQLQAERKKMAQQML- 953
Query: 291 LANEDKDRRIEE 302
D + ++EE
Sbjct: 954 ----DLEEQLEE 961
Score = 43.5 bits (101), Expect = 9e-04
Identities = 52/263 (19%), Positives = 110/263 (41%), Gaps = 46/263 (17%)
Query: 113 RLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLET 172
+LEGD + L LQ E +++R L+ ++ Q +L A + + E
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
Query: 173 QKLDLMTEVSELKLKLVGMEKEQREQE-EKQRKAEELLQEL----------RHLKIKVEE 221
+ L ++ +L+ L E+ +++ + EK+ AEEL L R L+ ++ +
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
Query: 222 LENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQR 281
LE E + + ++A V + +Q E+L ++L+ + ++ + R Q+++R
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQA-------EQLSNELATERSTAQKNESAR-QQLER 1792
Query: 282 ---------------LKMGMETLLLANEDKDRRIEE------------LTGLLNQYRKVK 314
+K ++ + A E K ++EE L + +K+K
Sbjct: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
Query: 315 EIVMVTQGPSERTLSINEEEPEG 337
EI++ + + E+ +G
Sbjct: 1853 EILLQVEDERKMAEQYKEQAEKG 1875
Score = 38.5 bits (88), Expect = 0.028
Identities = 45/228 (19%), Positives = 92/228 (40%), Gaps = 15/228 (6%)
Query: 86 KEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVC 145
KE SL++ + + E + L+ + E L+ + V + R LE
Sbjct: 1481 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1540
Query: 146 LEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLV-GMEKEQREQEEKQRK 204
+E + +L E+ LQ + E KL L + LK + ++ + EEK+R+
Sbjct: 1541 MEEMKTQLEELEDELQ-------ATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQ 1593
Query: 205 AEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRT 264
+ L E ELE+ER Q A K L++ D+ I+ + +
Sbjct: 1594 LQRQLHEYE------TELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL 1647
Query: 265 AALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRK 312
L ++ + +E++ + + + ++ +++ + L L Q ++
Sbjct: 1648 RKLQAQM-KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1694
Score = 36.6 bits (83), Expect = 0.10
Identities = 45/180 (25%), Positives = 77/180 (42%), Gaps = 22/180 (12%)
Query: 152 KLNAAEEMLQQELLSRTSLET------QKLDLMTEVSELKLKLVGMEKEQREQEEKQR-- 203
++ A E+ LQ+ + E QK +TE L + + E E + E+ R
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVR 912
Query: 204 ---KAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQ 260
K +EL + L ++ ++EE E+ Q + + K ++ L+EQ L++ E R Q
Sbjct: 913 LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ--LEEEEAARQKLQ 970
Query: 261 LSRTAALHSESHTERD---QEIQRLKMGMETLLLANEDKDRRIEEL-TGLLNQYRKVKEI 316
L + A E + + Q K+ E LL + RI +L T L + K K +
Sbjct: 971 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL-----EERISDLTTNLAEEEEKAKNL 1025
Score = 36.6 bits (83), Expect = 0.10
Identities = 48/223 (21%), Positives = 97/223 (43%), Gaps = 29/223 (13%)
Query: 103 SNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQ 162
S + ++ +LEGD Q++ L Q I +L++ L + +L AA L
Sbjct: 1049 SRQELEKLKRKLEGDASDFHEQIADLQAQ-------IAELKMQLAKKEEELQAALARLDD 1101
Query: 163 ELLSRTSLETQKLDLMTEVSELKLKLVG-------MEKEQREQEEKQRKAEELLQELRHL 215
E+ + + + +L +S+L+ L EK++R +L +EL L
Sbjct: 1102 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKR----------DLGEELEAL 1151
Query: 216 KIKVEE-LENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTE 274
K ++E+ L++ Q E + K + EV L++ + D E +Q+ H+++ E
Sbjct: 1152 KTELEDTLDSTATQQELRAK-REQEVTVLKKAL---DEETRSHEAQVQEMRQKHAQAVEE 1207
Query: 275 RDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIV 317
+++++ K L + ++ +L G L + K+ V
Sbjct: 1208 LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1250
Score = 32.7 bits (73), Expect = 1.5
Identities = 46/237 (19%), Positives = 108/237 (45%), Gaps = 32/237 (13%)
Query: 98 HHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAE 157
H S + ER AR + +K Q L +++EA ++ D + Q +L A
Sbjct: 1119 HISDLQEDLDSERAARNKAEK-----QKRDLGEELEALKTELEDT-LDSTATQQELRAKR 1172
Query: 158 EMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAE----------- 206
E Q+ + + +L+ + +V E++ K +E EQ E+ ++A+
Sbjct: 1173 E--QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLE 1230
Query: 207 ----ELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLS 262
+L ELR L +E+E+++ + E +++ +++ + + A + ++ +L +++
Sbjct: 1231 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1290
Query: 263 RTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRR---IEELTGLLNQYRKVKEI 316
+ +E+ E + +K+ + L+++ +D + EE LN K++++
Sbjct: 1291 SVTGMLNEA------EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1341
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 60.1 bits (144), Expect = 9e-09
Identities = 78/352 (22%), Positives = 147/352 (41%), Gaps = 25/352 (7%)
Query: 64 LELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNE--TYQERLARLEGDKESL 121
++L ++ A+L SQ+ T ++E + L+ E + Q++L K++L
Sbjct: 1311 IKLAKDVASLSSQLQD-TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1369
Query: 122 ILQVSVLTDQVEAQGEKIRDLEVCLEG-------HQVKLNAAEEMLQQELLSRTSLETQK 174
+S L Q+ +K++D +E Q ++ + +++ + LE K
Sbjct: 1370 ERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 1429
Query: 175 LDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLK 234
L E+ +L + L + E+KQRK ++LL E +++ K + E +R + E + K
Sbjct: 1430 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD-ERDRAEAEAREK 1488
Query: 235 ATKA-EVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLAN 293
TKA +A+ E+ E+ER + L S + + + L+ L
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Query: 294 EDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSK-WNATNKDPEEL 352
E+ ++EEL L K L +N + +G F + A ++ EE
Sbjct: 1549 EEMKTQLEELEDELQATEDAK-----------LRLEVNMQALKGQFERDLQARDEQNEEK 1597
Query: 353 FKQEMPPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQ 404
+Q T Q++L A+KKL L+DL ++ D + G +
Sbjct: 1598 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGRE 1648
Score = 50.4 bits (119), Expect = 7e-06
Identities = 52/215 (24%), Positives = 106/215 (49%), Gaps = 17/215 (7%)
Query: 86 KEWFEESLSQVNHHSAASNET--YQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL- 142
+E EE S ++ +A +E + R+A+LE + E + ++D+V ++ L
Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1777
Query: 143 -EVCLEGHQVKLN--AAEEMLQQELLSRTSLETQ----KLDLMTEVSELKLKLVGMEKE- 194
E+ E + N A +++ +Q R+ L K + ++ L+ K+ +E++
Sbjct: 1778 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1837
Query: 195 QREQEEKQRKAEELLQELRHLKIKVEELENERN---QYEWKLKATKAEVAQLQEQVALKD 251
++E EKQ + L Q+ + LK + ++E+ER QY+ + + A V QL+ Q+ +
Sbjct: 1838 EQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1897
Query: 252 AEIERLHS---QLSRTAALHSESHTERDQEIQRLK 283
E +R+++ +L R +ES+ +E+ LK
Sbjct: 1898 EESQRINANRRKLQRELDEATESNEAMGREVNALK 1932
Score = 48.5 bits (114), Expect = 3e-05
Identities = 52/276 (18%), Positives = 123/276 (44%), Gaps = 49/276 (17%)
Query: 62 EMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESL 121
E+ EL Q+ + L + K +E L Q A E + RLA + + E +
Sbjct: 881 ELKELEQKHSQLTEE---------KNLLQEQL-QAETELYAEAEEMRVRLAAKKQELEEI 930
Query: 122 ILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEV 181
+ ++ ++ E +G++++ + + L EE L++E +R L+ +K+ ++
Sbjct: 931 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDL---EEQLEEEEAARQKLQLEKVTAEAKI 987
Query: 182 SELKLKLVGME-------KEQR--------------EQEEKQRKAEELLQE----LRHLK 216
+L+ +++ M+ KE++ E+EEK + +L + + L+
Sbjct: 988 KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1047
Query: 217 IKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERD 276
+++++ E R + E + + + + EQ+A A+I L QL++ ++
Sbjct: 1048 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK-----------KE 1096
Query: 277 QEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRK 312
+E+Q ++ + + ++I EL G ++ ++
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Score = 43.9 bits (102), Expect = 7e-04
Identities = 34/132 (25%), Positives = 69/132 (52%), Gaps = 13/132 (9%)
Query: 174 KLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKL 233
K+ + +V+ + ++ E E ++ +E+Q+KAE EL+ L+ K +L E+N + +L
Sbjct: 847 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAEN---ELKELEQKHSQLTEEKNLLQEQL 903
Query: 234 KATK---AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLL 290
+A AE +++ ++A K E+E + ++ A L E + + +R KM + L
Sbjct: 904 QAETELYAEAEEMRVRLAAKKQELEEILHEME--ARLEEEEDRGQQLQAERKKMAQQML- 960
Query: 291 LANEDKDRRIEE 302
D + ++EE
Sbjct: 961 ----DLEEQLEE 968
Score = 43.5 bits (101), Expect = 9e-04
Identities = 52/263 (19%), Positives = 110/263 (41%), Gaps = 46/263 (17%)
Query: 113 RLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLET 172
+LEGD + L LQ E +++R L+ ++ Q +L A + + E
Sbjct: 1628 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1687
Query: 173 QKLDLMTEVSELKLKLVGMEKEQREQE-EKQRKAEELLQEL----------RHLKIKVEE 221
+ L ++ +L+ L E+ +++ + EK+ AEEL L R L+ ++ +
Sbjct: 1688 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1747
Query: 222 LENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQR 281
LE E + + ++A V + +Q E+L ++L+ + ++ + R Q+++R
Sbjct: 1748 LEEELEEEQGNMEAMSDRVRKATQQA-------EQLSNELATERSTAQKNESAR-QQLER 1799
Query: 282 ---------------LKMGMETLLLANEDKDRRIEE------------LTGLLNQYRKVK 314
+K ++ + A E K ++EE L + +K+K
Sbjct: 1800 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1859
Query: 315 EIVMVTQGPSERTLSINEEEPEG 337
EI++ + + E+ +G
Sbjct: 1860 EILLQVEDERKMAEQYKEQAEKG 1882
Score = 38.5 bits (88), Expect = 0.028
Identities = 45/228 (19%), Positives = 92/228 (40%), Gaps = 15/228 (6%)
Query: 86 KEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVC 145
KE SL++ + + E + L+ + E L+ + V + R LE
Sbjct: 1488 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1547
Query: 146 LEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLV-GMEKEQREQEEKQRK 204
+E + +L E+ LQ + E KL L + LK + ++ + EEK+R+
Sbjct: 1548 MEEMKTQLEELEDELQ-------ATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQ 1600
Query: 205 AEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRT 264
+ L E ELE+ER Q A K L++ D+ I+ + +
Sbjct: 1601 LQRQLHEYE------TELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL 1654
Query: 265 AALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRK 312
L ++ + +E++ + + + ++ +++ + L L Q ++
Sbjct: 1655 RKLQAQM-KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1701
Score = 36.6 bits (83), Expect = 0.10
Identities = 45/180 (25%), Positives = 77/180 (42%), Gaps = 22/180 (12%)
Query: 152 KLNAAEEMLQQELLSRTSLET------QKLDLMTEVSELKLKLVGMEKEQREQEEKQR-- 203
++ A E+ LQ+ + E QK +TE L + + E E + E+ R
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVR 919
Query: 204 ---KAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQ 260
K +EL + L ++ ++EE E+ Q + + K ++ L+EQ L++ E R Q
Sbjct: 920 LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ--LEEEEAARQKLQ 977
Query: 261 LSRTAALHSESHTERD---QEIQRLKMGMETLLLANEDKDRRIEEL-TGLLNQYRKVKEI 316
L + A E + + Q K+ E LL + RI +L T L + K K +
Sbjct: 978 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL-----EERISDLTTNLAEEEEKAKNL 1032
Score = 36.6 bits (83), Expect = 0.10
Identities = 48/223 (21%), Positives = 97/223 (43%), Gaps = 29/223 (13%)
Query: 103 SNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQ 162
S + ++ +LEGD Q++ L Q I +L++ L + +L AA L
Sbjct: 1056 SRQELEKLKRKLEGDASDFHEQIADLQAQ-------IAELKMQLAKKEEELQAALARLDD 1108
Query: 163 ELLSRTSLETQKLDLMTEVSELKLKLVG-------MEKEQREQEEKQRKAEELLQELRHL 215
E+ + + + +L +S+L+ L EK++R +L +EL L
Sbjct: 1109 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKR----------DLGEELEAL 1158
Query: 216 KIKVEE-LENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTE 274
K ++E+ L++ Q E + K + EV L++ + D E +Q+ H+++ E
Sbjct: 1159 KTELEDTLDSTATQQELRAK-REQEVTVLKKAL---DEETRSHEAQVQEMRQKHAQAVEE 1214
Query: 275 RDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIV 317
+++++ K L + ++ +L G L + K+ V
Sbjct: 1215 LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1257
Score = 32.7 bits (73), Expect = 1.5
Identities = 46/237 (19%), Positives = 108/237 (45%), Gaps = 32/237 (13%)
Query: 98 HHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAE 157
H S + ER AR + +K Q L +++EA ++ D + Q +L A
Sbjct: 1126 HISDLQEDLDSERAARNKAEK-----QKRDLGEELEALKTELEDT-LDSTATQQELRAKR 1179
Query: 158 EMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAE----------- 206
E Q+ + + +L+ + +V E++ K +E EQ E+ ++A+
Sbjct: 1180 E--QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLE 1237
Query: 207 ----ELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLS 262
+L ELR L +E+E+++ + E +++ +++ + + A + ++ +L +++
Sbjct: 1238 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1297
Query: 263 RTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRR---IEELTGLLNQYRKVKEI 316
+ +E+ E + +K+ + L+++ +D + EE LN K++++
Sbjct: 1298 SVTGMLNEA------EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1348
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 60.1 bits (144), Expect = 9e-09
Identities = 78/352 (22%), Positives = 147/352 (41%), Gaps = 25/352 (7%)
Query: 64 LELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNE--TYQERLARLEGDKESL 121
++L ++ A+L SQ+ T ++E + L+ E + Q++L K++L
Sbjct: 1311 IKLAKDVASLSSQLQD-TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1369
Query: 122 ILQVSVLTDQVEAQGEKIRDLEVCLEG-------HQVKLNAAEEMLQQELLSRTSLETQK 174
+S L Q+ +K++D +E Q ++ + +++ + LE K
Sbjct: 1370 ERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 1429
Query: 175 LDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLK 234
L E+ +L + L + E+KQRK ++LL E +++ K + E +R + E + K
Sbjct: 1430 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD-ERDRAEAEAREK 1488
Query: 235 ATKA-EVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLAN 293
TKA +A+ E+ E+ER + L S + + + L+ L
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Query: 294 EDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSK-WNATNKDPEEL 352
E+ ++EEL L K L +N + +G F + A ++ EE
Sbjct: 1549 EEMKTQLEELEDELQATEDAK-----------LRLEVNMQALKGQFERDLQARDEQNEEK 1597
Query: 353 FKQEMPPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQ 404
+Q T Q++L A+KKL L+DL ++ D + G +
Sbjct: 1598 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGRE 1648
Score = 50.4 bits (119), Expect = 7e-06
Identities = 52/215 (24%), Positives = 106/215 (49%), Gaps = 17/215 (7%)
Query: 86 KEWFEESLSQVNHHSAASNET--YQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL- 142
+E EE S ++ +A +E + R+A+LE + E + ++D+V ++ L
Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1777
Query: 143 -EVCLEGHQVKLN--AAEEMLQQELLSRTSLETQ----KLDLMTEVSELKLKLVGMEKE- 194
E+ E + N A +++ +Q R+ L K + ++ L+ K+ +E++
Sbjct: 1778 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1837
Query: 195 QREQEEKQRKAEELLQELRHLKIKVEELENERN---QYEWKLKATKAEVAQLQEQVALKD 251
++E EKQ + L Q+ + LK + ++E+ER QY+ + + A V QL+ Q+ +
Sbjct: 1838 EQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1897
Query: 252 AEIERLHS---QLSRTAALHSESHTERDQEIQRLK 283
E +R+++ +L R +ES+ +E+ LK
Sbjct: 1898 EESQRINANRRKLQRELDEATESNEAMGREVNALK 1932
Score = 48.5 bits (114), Expect = 3e-05
Identities = 52/276 (18%), Positives = 123/276 (44%), Gaps = 49/276 (17%)
Query: 62 EMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESL 121
E+ EL Q+ + L + K +E L Q A E + RLA + + E +
Sbjct: 881 ELKELEQKHSQLTEE---------KNLLQEQL-QAETELYAEAEEMRVRLAAKKQELEEI 930
Query: 122 ILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEV 181
+ ++ ++ E +G++++ + + L EE L++E +R L+ +K+ ++
Sbjct: 931 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDL---EEQLEEEEAARQKLQLEKVTAEAKI 987
Query: 182 SELKLKLVGME-------KEQR--------------EQEEKQRKAEELLQE----LRHLK 216
+L+ +++ M+ KE++ E+EEK + +L + + L+
Sbjct: 988 KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1047
Query: 217 IKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERD 276
+++++ E R + E + + + + EQ+A A+I L QL++ ++
Sbjct: 1048 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK-----------KE 1096
Query: 277 QEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRK 312
+E+Q ++ + + ++I EL G ++ ++
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Score = 43.9 bits (102), Expect = 7e-04
Identities = 34/132 (25%), Positives = 69/132 (52%), Gaps = 13/132 (9%)
Query: 174 KLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKL 233
K+ + +V+ + ++ E E ++ +E+Q+KAE EL+ L+ K +L E+N + +L
Sbjct: 847 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAEN---ELKELEQKHSQLTEEKNLLQEQL 903
Query: 234 KATK---AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLL 290
+A AE +++ ++A K E+E + ++ A L E + + +R KM + L
Sbjct: 904 QAETELYAEAEEMRVRLAAKKQELEEILHEME--ARLEEEEDRGQQLQAERKKMAQQML- 960
Query: 291 LANEDKDRRIEE 302
D + ++EE
Sbjct: 961 ----DLEEQLEE 968
Score = 43.5 bits (101), Expect = 9e-04
Identities = 52/263 (19%), Positives = 110/263 (41%), Gaps = 46/263 (17%)
Query: 113 RLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLET 172
+LEGD + L LQ E +++R L+ ++ Q +L A + + E
Sbjct: 1628 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1687
Query: 173 QKLDLMTEVSELKLKLVGMEKEQREQE-EKQRKAEELLQEL----------RHLKIKVEE 221
+ L ++ +L+ L E+ +++ + EK+ AEEL L R L+ ++ +
Sbjct: 1688 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1747
Query: 222 LENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQR 281
LE E + + ++A V + +Q E+L ++L+ + ++ + R Q+++R
Sbjct: 1748 LEEELEEEQGNMEAMSDRVRKATQQA-------EQLSNELATERSTAQKNESAR-QQLER 1799
Query: 282 ---------------LKMGMETLLLANEDKDRRIEE------------LTGLLNQYRKVK 314
+K ++ + A E K ++EE L + +K+K
Sbjct: 1800 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1859
Query: 315 EIVMVTQGPSERTLSINEEEPEG 337
EI++ + + E+ +G
Sbjct: 1860 EILLQVEDERKMAEQYKEQAEKG 1882
Score = 38.5 bits (88), Expect = 0.028
Identities = 45/228 (19%), Positives = 92/228 (40%), Gaps = 15/228 (6%)
Query: 86 KEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVC 145
KE SL++ + + E + L+ + E L+ + V + R LE
Sbjct: 1488 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1547
Query: 146 LEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLV-GMEKEQREQEEKQRK 204
+E + +L E+ LQ + E KL L + LK + ++ + EEK+R+
Sbjct: 1548 MEEMKTQLEELEDELQ-------ATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQ 1600
Query: 205 AEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRT 264
+ L E ELE+ER Q A K L++ D+ I+ + +
Sbjct: 1601 LQRQLHEYE------TELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL 1654
Query: 265 AALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRK 312
L ++ + +E++ + + + ++ +++ + L L Q ++
Sbjct: 1655 RKLQAQM-KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1701
Score = 36.6 bits (83), Expect = 0.10
Identities = 45/180 (25%), Positives = 77/180 (42%), Gaps = 22/180 (12%)
Query: 152 KLNAAEEMLQQELLSRTSLET------QKLDLMTEVSELKLKLVGMEKEQREQEEKQR-- 203
++ A E+ LQ+ + E QK +TE L + + E E + E+ R
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVR 919
Query: 204 ---KAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQ 260
K +EL + L ++ ++EE E+ Q + + K ++ L+EQ L++ E R Q
Sbjct: 920 LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ--LEEEEAARQKLQ 977
Query: 261 LSRTAALHSESHTERD---QEIQRLKMGMETLLLANEDKDRRIEEL-TGLLNQYRKVKEI 316
L + A E + + Q K+ E LL + RI +L T L + K K +
Sbjct: 978 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL-----EERISDLTTNLAEEEEKAKNL 1032
Score = 36.6 bits (83), Expect = 0.10
Identities = 48/223 (21%), Positives = 97/223 (43%), Gaps = 29/223 (13%)
Query: 103 SNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQ 162
S + ++ +LEGD Q++ L Q I +L++ L + +L AA L
Sbjct: 1056 SRQELEKLKRKLEGDASDFHEQIADLQAQ-------IAELKMQLAKKEEELQAALARLDD 1108
Query: 163 ELLSRTSLETQKLDLMTEVSELKLKLVG-------MEKEQREQEEKQRKAEELLQELRHL 215
E+ + + + +L +S+L+ L EK++R +L +EL L
Sbjct: 1109 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKR----------DLGEELEAL 1158
Query: 216 KIKVEE-LENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTE 274
K ++E+ L++ Q E + K + EV L++ + D E +Q+ H+++ E
Sbjct: 1159 KTELEDTLDSTATQQELRAK-REQEVTVLKKAL---DEETRSHEAQVQEMRQKHAQAVEE 1214
Query: 275 RDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIV 317
+++++ K L + ++ +L G L + K+ V
Sbjct: 1215 LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1257
Score = 32.7 bits (73), Expect = 1.5
Identities = 46/237 (19%), Positives = 108/237 (45%), Gaps = 32/237 (13%)
Query: 98 HHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAE 157
H S + ER AR + +K Q L +++EA ++ D + Q +L A
Sbjct: 1126 HISDLQEDLDSERAARNKAEK-----QKRDLGEELEALKTELEDT-LDSTATQQELRAKR 1179
Query: 158 EMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAE----------- 206
E Q+ + + +L+ + +V E++ K +E EQ E+ ++A+
Sbjct: 1180 E--QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLE 1237
Query: 207 ----ELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLS 262
+L ELR L +E+E+++ + E +++ +++ + + A + ++ +L +++
Sbjct: 1238 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1297
Query: 263 RTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRR---IEELTGLLNQYRKVKEI 316
+ +E+ E + +K+ + L+++ +D + EE LN K++++
Sbjct: 1298 SVTGMLNEA------EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1348
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 60.1 bits (144), Expect = 9e-09
Identities = 78/352 (22%), Positives = 147/352 (41%), Gaps = 25/352 (7%)
Query: 64 LELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNE--TYQERLARLEGDKESL 121
++L ++ A+L SQ+ T ++E + L+ E + Q++L K++L
Sbjct: 1304 IKLAKDVASLSSQLQD-TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1362
Query: 122 ILQVSVLTDQVEAQGEKIRDLEVCLEG-------HQVKLNAAEEMLQQELLSRTSLETQK 174
+S L Q+ +K++D +E Q ++ + +++ + LE K
Sbjct: 1363 ERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 1422
Query: 175 LDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLK 234
L E+ +L + L + E+KQRK ++LL E +++ K + E +R + E + K
Sbjct: 1423 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD-ERDRAEAEAREK 1481
Query: 235 ATKA-EVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLAN 293
TKA +A+ E+ E+ER + L S + + + L+ L
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Query: 294 EDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSK-WNATNKDPEEL 352
E+ ++EEL L K L +N + +G F + A ++ EE
Sbjct: 1542 EEMKTQLEELEDELQATEDAK-----------LRLEVNMQALKGQFERDLQARDEQNEEK 1590
Query: 353 FKQEMPPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQ 404
+Q T Q++L A+KKL L+DL ++ D + G +
Sbjct: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA-DSAIKGRE 1641
Score = 50.4 bits (119), Expect = 7e-06
Identities = 52/215 (24%), Positives = 106/215 (49%), Gaps = 17/215 (7%)
Query: 86 KEWFEESLSQVNHHSAASNET--YQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL- 142
+E EE S ++ +A +E + R+A+LE + E + ++D+V ++ L
Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1770
Query: 143 -EVCLEGHQVKLN--AAEEMLQQELLSRTSLETQ----KLDLMTEVSELKLKLVGMEKE- 194
E+ E + N A +++ +Q R+ L K + ++ L+ K+ +E++
Sbjct: 1771 NELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQV 1830
Query: 195 QREQEEKQRKAEELLQELRHLKIKVEELENERN---QYEWKLKATKAEVAQLQEQVALKD 251
++E EKQ + L Q+ + LK + ++E+ER QY+ + + A V QL+ Q+ +
Sbjct: 1831 EQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1890
Query: 252 AEIERLHS---QLSRTAALHSESHTERDQEIQRLK 283
E +R+++ +L R +ES+ +E+ LK
Sbjct: 1891 EESQRINANRRKLQRELDEATESNEAMGREVNALK 1925
Score = 48.5 bits (114), Expect = 3e-05
Identities = 52/276 (18%), Positives = 123/276 (44%), Gaps = 49/276 (17%)
Query: 62 EMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESL 121
E+ EL Q+ + L + K +E L Q A E + RLA + + E +
Sbjct: 874 ELKELEQKHSQLTEE---------KNLLQEQL-QAETELYAEAEEMRVRLAAKKQELEEI 923
Query: 122 ILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEV 181
+ ++ ++ E +G++++ + + L EE L++E +R L+ +K+ ++
Sbjct: 924 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDL---EEQLEEEEAARQKLQLEKVTAEAKI 980
Query: 182 SELKLKLVGME-------KEQR--------------EQEEKQRKAEELLQE----LRHLK 216
+L+ +++ M+ KE++ E+EEK + +L + + L+
Sbjct: 981 KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1040
Query: 217 IKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERD 276
+++++ E R + E + + + + EQ+A A+I L QL++ ++
Sbjct: 1041 VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK-----------KE 1089
Query: 277 QEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRK 312
+E+Q ++ + + ++I EL G ++ ++
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Score = 43.9 bits (102), Expect = 7e-04
Identities = 34/132 (25%), Positives = 69/132 (52%), Gaps = 13/132 (9%)
Query: 174 KLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKL 233
K+ + +V+ + ++ E E ++ +E+Q+KAE EL+ L+ K +L E+N + +L
Sbjct: 840 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAEN---ELKELEQKHSQLTEEKNLLQEQL 896
Query: 234 KATK---AEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLL 290
+A AE +++ ++A K E+E + ++ A L E + + +R KM + L
Sbjct: 897 QAETELYAEAEEMRVRLAAKKQELEEILHEME--ARLEEEEDRGQQLQAERKKMAQQML- 953
Query: 291 LANEDKDRRIEE 302
D + ++EE
Sbjct: 954 ----DLEEQLEE 961
Score = 43.5 bits (101), Expect = 9e-04
Identities = 52/263 (19%), Positives = 110/263 (41%), Gaps = 46/263 (17%)
Query: 113 RLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLET 172
+LEGD + L LQ E +++R L+ ++ Q +L A + + E
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
Query: 173 QKLDLMTEVSELKLKLVGMEKEQREQE-EKQRKAEELLQEL----------RHLKIKVEE 221
+ L ++ +L+ L E+ +++ + EK+ AEEL L R L+ ++ +
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
Query: 222 LENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQR 281
LE E + + ++A V + +Q E+L ++L+ + ++ + R Q+++R
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQA-------EQLSNELATERSTAQKNESAR-QQLER 1792
Query: 282 ---------------LKMGMETLLLANEDKDRRIEE------------LTGLLNQYRKVK 314
+K ++ + A E K ++EE L + +K+K
Sbjct: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
Query: 315 EIVMVTQGPSERTLSINEEEPEG 337
EI++ + + E+ +G
Sbjct: 1853 EILLQVEDERKMAEQYKEQAEKG 1875
Score = 38.5 bits (88), Expect = 0.028
Identities = 45/228 (19%), Positives = 92/228 (40%), Gaps = 15/228 (6%)
Query: 86 KEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVC 145
KE SL++ + + E + L+ + E L+ + V + R LE
Sbjct: 1481 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1540
Query: 146 LEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLV-GMEKEQREQEEKQRK 204
+E + +L E+ LQ + E KL L + LK + ++ + EEK+R+
Sbjct: 1541 MEEMKTQLEELEDELQ-------ATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQ 1593
Query: 205 AEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRT 264
+ L E ELE+ER Q A K L++ D+ I+ + +
Sbjct: 1594 LQRQLHEYE------TELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL 1647
Query: 265 AALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRK 312
L ++ + +E++ + + + ++ +++ + L L Q ++
Sbjct: 1648 RKLQAQM-KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1694
Score = 36.6 bits (83), Expect = 0.10
Identities = 45/180 (25%), Positives = 77/180 (42%), Gaps = 22/180 (12%)
Query: 152 KLNAAEEMLQQELLSRTSLET------QKLDLMTEVSELKLKLVGMEKEQREQEEKQR-- 203
++ A E+ LQ+ + E QK +TE L + + E E + E+ R
Sbjct: 853 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVR 912
Query: 204 ---KAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQ 260
K +EL + L ++ ++EE E+ Q + + K ++ L+EQ L++ E R Q
Sbjct: 913 LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ--LEEEEAARQKLQ 970
Query: 261 LSRTAALHSESHTERD---QEIQRLKMGMETLLLANEDKDRRIEEL-TGLLNQYRKVKEI 316
L + A E + + Q K+ E LL + RI +L T L + K K +
Sbjct: 971 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL-----EERISDLTTNLAEEEEKAKNL 1025
Score = 36.6 bits (83), Expect = 0.10
Identities = 48/223 (21%), Positives = 97/223 (43%), Gaps = 29/223 (13%)
Query: 103 SNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQ 162
S + ++ +LEGD Q++ L Q I +L++ L + +L AA L
Sbjct: 1049 SRQELEKLKRKLEGDASDFHEQIADLQAQ-------IAELKMQLAKKEEELQAALARLDD 1101
Query: 163 ELLSRTSLETQKLDLMTEVSELKLKLVG-------MEKEQREQEEKQRKAEELLQELRHL 215
E+ + + + +L +S+L+ L EK++R +L +EL L
Sbjct: 1102 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKR----------DLGEELEAL 1151
Query: 216 KIKVEE-LENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTE 274
K ++E+ L++ Q E + K + EV L++ + D E +Q+ H+++ E
Sbjct: 1152 KTELEDTLDSTATQQELRAK-REQEVTVLKKAL---DEETRSHEAQVQEMRQKHAQAVEE 1207
Query: 275 RDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIV 317
+++++ K L + ++ +L G L + K+ V
Sbjct: 1208 LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1250
Score = 32.7 bits (73), Expect = 1.5
Identities = 46/237 (19%), Positives = 108/237 (45%), Gaps = 32/237 (13%)
Query: 98 HHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAE 157
H S + ER AR + +K Q L +++EA ++ D + Q +L A
Sbjct: 1119 HISDLQEDLDSERAARNKAEK-----QKRDLGEELEALKTELEDT-LDSTATQQELRAKR 1172
Query: 158 EMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAE----------- 206
E Q+ + + +L+ + +V E++ K +E EQ E+ ++A+
Sbjct: 1173 E--QEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLE 1230
Query: 207 ----ELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLS 262
+L ELR L +E+E+++ + E +++ +++ + + A + ++ +L +++
Sbjct: 1231 KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1290
Query: 263 RTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRR---IEELTGLLNQYRKVKEI 316
+ +E+ E + +K+ + L+++ +D + EE LN K++++
Sbjct: 1291 SVTGMLNEA------EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1341
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 59.3 bits (142), Expect = 2e-08
Identities = 77/304 (25%), Positives = 129/304 (42%), Gaps = 26/304 (8%)
Query: 108 QERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEM---LQQEL 164
+E AR +K+ L LQ S L D + + + +E E + L AE + L+++
Sbjct: 1354 EEEEARKNLEKQVLALQ-SQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKA 1412
Query: 165 LSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELEN 224
L+ LE K L E+ +L + L + E+KQ+K ++LL E + + + E E
Sbjct: 1413 LAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAE-ER 1471
Query: 225 ERNQYEWKLKATKA-EVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLK 283
+R + E + K TKA +A+ E+ E ER + QL S + + + L+
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELE 1531
Query: 284 MGMETLLLANEDKDRRIEELTGLLNQYRKVK---EIVM-VTQGPSERTLSINEEEPEGGF 339
L E+ ++EEL L K E+ M + ER L +E+ E
Sbjct: 1532 KSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNE--- 1588
Query: 340 SKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRS--ESVD 397
K K EL + R Q++L ++KK+ L+DL + E+ +
Sbjct: 1589 EKKRLLIKQVRELEAELEDER-----------KQRALAVASKKKMEIDLKDLEAQIEAAN 1637
Query: 398 KCMD 401
K D
Sbjct: 1638 KARD 1641
Score = 58.2 bits (139), Expect = 3e-08
Identities = 61/239 (25%), Positives = 108/239 (45%), Gaps = 35/239 (14%)
Query: 108 QERLARLEGDKESLILQVSVLTD-------QVEAQGEKIRDLEVCLEGHQVKLNAAEEML 160
+E + LE I + ++ D Q+ + EK ++L +V ++ EE L
Sbjct: 984 EEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERL 1043
Query: 161 QQELLSR--------------TSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAE 206
++E +R T L+ Q +L ++ ELKL+L +KE+ Q R +
Sbjct: 1044 KKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLA--KKEEELQGALARGDD 1101
Query: 207 ELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLS---R 263
E L + LK+ V EL+ + + + ++ KA + ++Q E+E L ++L
Sbjct: 1102 ETLHKNNALKV-VRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1160
Query: 264 TAALHSESHTERDQEIQRLKMGMETLLLANED--KDRR------IEELTGLLNQYRKVK 314
T A E T+R+QE+ LK +E +E +D R +EEL+ L Q ++ K
Sbjct: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFK 1219
Score = 51.2 bits (121), Expect = 4e-06
Identities = 71/319 (22%), Positives = 130/319 (40%), Gaps = 53/319 (16%)
Query: 59 LALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDK 118
L E+L+L +E A+ A E + L+ +SA+ + RLE
Sbjct: 1685 LEAEILQLQEELAS------SERARRHAEQERDELADEITNSASGKSALLDEKRRLEARI 1738
Query: 119 ESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLM 178
L ++ +E ++ R + ++ +L A Q+ +R LE Q +L
Sbjct: 1739 AQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELK 1798
Query: 179 TEVSEL------KLKL--------VGMEKEQREQEEKQRKAEELL-----QELRHLKIKV 219
++ EL K K +G +EQ EQE K+R A L ++L+ + ++V
Sbjct: 1799 AKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQV 1858
Query: 220 EELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEI 279
E+ +QY+ +++ A + QL+ Q L++AE E + SR
Sbjct: 1859 EDERRHADQYKEQMEKANARMKQLKRQ--LEEAEEEATRANASR---------------- 1900
Query: 280 QRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSER-------TLSINE 332
++L+ ++ ANE R E++ L N+ R+ I + R +L +++
Sbjct: 1901 RKLQRELDDATEANEGLSR---EVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSD 1957
Query: 333 EEPEGGFSKWNATNKDPEE 351
++ E S N T E
Sbjct: 1958 DDTESKTSDVNETQPPQSE 1976
Score = 50.1 bits (118), Expect = 9e-06
Identities = 82/362 (22%), Positives = 154/362 (42%), Gaps = 33/362 (9%)
Query: 54 IEDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLAR 113
+ +L+ ALE E + A + + A ++E E L Q A + Q
Sbjct: 1176 VAELKKALE--EETKNHEAQIQDMRQRHATALEE-LSEQLEQAKRFKANLEKNKQG---- 1228
Query: 114 LEGDKESLILQVSVLTDQVEAQGE-KIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLET 172
LE D + L +V VL QV+A+ E K + L+ ++ K++ + L+ EL + S
Sbjct: 1229 LETDNKELACEVKVL-QQVKAESEHKRKKLDAQVQELHAKVSEGDR-LRVELAEKASKLQ 1286
Query: 173 QKLD-LMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKI----KVEELENERN 227
+LD + T + E + K + K+ E + + +ELLQE K+ ++ +LE E+N
Sbjct: 1287 NELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKN 1346
Query: 228 QYEWKLKATKAEVAQLQEQVALKDAEI----ERLHSQLSRTAALHSESHTERDQEIQRLK 283
+ + + + L++QV +++ +++ L +L E+ + ++ + L
Sbjct: 1347 SLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESL-EEAKKKLLKDAEALS 1405
Query: 284 MGMETLLLANEDKDR-------RIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPE 336
+E LA + ++ +++LT L+ R+V + Q ++ L+ E
Sbjct: 1406 QRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLA-----EE 1460
Query: 337 GGFSKWNATNKDPEELFKQEMPPRC-SSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSES 395
S A +D E +E + S L K R K+L +EDL S
Sbjct: 1461 KSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSK 1520
Query: 396 VD 397
D
Sbjct: 1521 DD 1522
Score = 49.3 bits (116), Expect = 2e-05
Identities = 45/215 (20%), Positives = 99/215 (46%), Gaps = 16/215 (7%)
Query: 53 LIEDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLA 112
L+E+ + E L+ E A ++ AA +E L ++ H + E +ER
Sbjct: 885 LLEEKNILAEQLQAETELFAEAEEMRARLAAKKQE-----LEEILHDLESRVEEEEERNQ 939
Query: 113 RLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLET 172
L+ +K+ + + L +Q++ + + L++ +V A + +++E+L LE
Sbjct: 940 ILQNEKKKMQAHIQDLEEQLDEEEGARQKLQL----EKVTAEAKIKKMEEEILL---LED 992
Query: 173 QKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQE----LRHLKIKVEELENERNQ 228
Q + E ++ ++ + E+EEK + ++ + + L+ ++++ E R +
Sbjct: 993 QNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQE 1052
Query: 229 YEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSR 263
E + E LQ+Q+A A+I+ L QL++
Sbjct: 1053 LEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAK 1087
Score = 48.5 bits (114), Expect = 3e-05
Identities = 60/268 (22%), Positives = 113/268 (42%), Gaps = 47/268 (17%)
Query: 86 KEWFEESLSQVN---HHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL 142
KE FE Q+ +S + + + LE K +L QV + Q+E ++++
Sbjct: 1499 KEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
Query: 143 EVCLEGHQVKLNAAEEMLQQELLSRTSL-ETQKLDLMTEVSELKLKLVGMEKEQREQEEK 201
E +V + A + +++L +R E +K L+ +V EL+ +L K++
Sbjct: 1559 EDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVAS 1618
Query: 202 QRKAE------------------ELLQELRHLKIKVEELENE--------------RNQY 229
++K E E++++LR L+ ++++ + E +
Sbjct: 1619 KKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Query: 230 EWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETL 289
E KLK+ +AE+ QLQE++A +E R H++ R E EI G L
Sbjct: 1679 EKKLKSLEAEILQLQEELA--SSERARRHAEQER---------DELADEITNSASGKSAL 1727
Query: 290 LLANEDKDRRIEELTGLLNQYRKVKEIV 317
L + RI +L L + + E++
Sbjct: 1728 LDEKRRLEARIAQLEEELEEEQSNMELL 1755
Score = 45.8 bits (107), Expect = 2e-04
Identities = 63/259 (24%), Positives = 108/259 (41%), Gaps = 51/259 (19%)
Query: 108 QERLARLEGDKESLILQVSVLTDQVE---AQGE-----KIRDLEVCLEGHQVKLNAAEEM 159
Q+++A L+ + L LQ++ ++++ A+G+ K L+V E Q ++ +E
Sbjct: 1068 QDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRE-LQAQIAELQED 1126
Query: 160 LQQELLSRTSLETQKLDLMTEVSELKLKL--------------------VGMEKEQREQE 199
+ E SR E QK DL E+ LK +L V K+ E+E
Sbjct: 1127 FESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEE 1186
Query: 200 EKQRKA-------------EELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQ 246
K +A EEL ++L K LE + E K EV LQ+
Sbjct: 1187 TKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQV 1246
Query: 247 VALK-------DAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRR 299
A DA+++ LH+++S L E E+ ++Q + TLL E K +
Sbjct: 1247 KAESEHKRKKLDAQVQELHAKVSEGDRLRVEL-AEKASKLQNELDNVSTLLEEAEKKGIK 1305
Query: 300 I-EELTGLLNQYRKVKEIV 317
++ L +Q + +E++
Sbjct: 1306 FAKDAASLESQLQDTQELL 1324
Score = 41.2 bits (95), Expect = 0.004
Identities = 42/212 (19%), Positives = 96/212 (45%), Gaps = 22/212 (10%)
Query: 122 ILQVSVLTDQVEAQGE---KIRDLEVCLEG--------HQVKL---NAAEEMLQQELLSR 167
+LQV+ ++++A+ E K+++ + +EG HQ L N E LQ E
Sbjct: 844 LLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELF 903
Query: 168 TSLETQKLDLMTEVSELKLKLVGMEKEQREQEEK----QRKAEELLQELRHLKIKVEELE 223
E + L + EL+ L +E E+EE+ Q + +++ ++ L+ +++E E
Sbjct: 904 AEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE 963
Query: 224 NERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLK 283
R + + + +A++ +++E++ L +E +S+ + L + E ++ +
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILL----LEDQNSKFIKEKKLMEDRIAECSSQLAEEE 1019
Query: 284 MGMETLLLANEDKDRRIEELTGLLNQYRKVKE 315
+ L ++ I +L L + K ++
Sbjct: 1020 EKAKNLAKIRNKQEVMISDLEERLKKEEKTRQ 1051
Score = 39.7 bits (91), Expect = 0.012
Identities = 37/136 (27%), Positives = 69/136 (50%), Gaps = 15/136 (11%)
Query: 174 KLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKL 233
K+ + +V+ + +L ++E + +EKQ K E L+E+ K ++L E+N +L
Sbjct: 840 KVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMER---KHQQLLEEKNILAEQL 896
Query: 234 KATK---AEVAQLQEQVALKDAEIER-LHSQLSRTAALHSESHTERDQEIQRLKMGMETL 289
+A AE +++ ++A K E+E LH SR E ER+Q +Q K M+
Sbjct: 897 QAETELFAEAEEMRARLAAKKQELEEILHDLESRV-----EEEEERNQILQNEKKKMQAH 951
Query: 290 LLANEDKDRRIEELTG 305
+ +D + +++E G
Sbjct: 952 I---QDLEEQLDEEEG 964
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 59.3 bits (142), Expect = 2e-08
Identities = 60/250 (24%), Positives = 112/250 (44%), Gaps = 17/250 (6%)
Query: 108 QERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSR 167
+E A+L+ E Q L + + ++ DL + L+ Q L EE + + S+
Sbjct: 865 KEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSK 924
Query: 168 TSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERN 227
LE + +L V E+E+ E + +L E LK ++++LE
Sbjct: 925 IQLEARVKELSERV----------EEEEEINSELTARGRKLEDECFELKKEIDDLETMLV 974
Query: 228 QYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGME 287
+ E + + T+ +V L E+V + +I S+L+R A + E+H + ++ + +
Sbjct: 975 KSEKEKRTTEHKVKNLTEEVEFLNEDI----SKLNRAAKVVQEAHQQTLDDLHMEEEKLS 1030
Query: 288 TLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNK 347
+L AN +++++EL G L Q RK + E L +N E E + ++
Sbjct: 1031 SLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESME---NLESSQRH 1087
Query: 348 DPEELFKQEM 357
EEL K+E+
Sbjct: 1088 LAEELRKKEL 1097
Score = 48.9 bits (115), Expect = 2e-05
Identities = 59/210 (28%), Positives = 91/210 (43%), Gaps = 30/210 (14%)
Query: 111 LARLEGDKESLILQVSVLTDQVEAQGEKIRDL----EVCLEGHQVKLNAAEEMLQQELLS 166
L + E +K + +V LT++VE E I L +V E HQ L+ +++E LS
Sbjct: 973 LVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLH--MEEEKLS 1030
Query: 167 RTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAE-------ELLQEL----RHL 215
SL L L +V EL+ L K + E + K E E ++ L RHL
Sbjct: 1031 --SLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHL 1088
Query: 216 KIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTER 275
++ + E E +Q K++ K VAQLQ+ V +I+ L +L ++ ER
Sbjct: 1089 AEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERER 1148
Query: 276 DQEIQRLKMGMETLLLANEDKDRRIEELTG 305
Q L D + R+EE+ G
Sbjct: 1149 ADLTQDL-----------ADLNERLEEVGG 1167
Score = 43.5 bits (101), Expect = 9e-04
Identities = 68/304 (22%), Positives = 116/304 (38%), Gaps = 27/304 (8%)
Query: 23 TKTGADLSDGTCEPGLASPASYMNPFPVLHLIEDLRLALEMLELPQERAALLSQIPGPTA 82
T+ ADL++ E G +S A L + + + L E A L + T+
Sbjct: 1152 TQDLADLNERLEEVGGSSLAQ-------LEITKKQETKFQKLHRDMEEATLHFET---TS 1201
Query: 83 AYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL 142
A +K+ +SL+++ E Q+ +LE DK L L+V L +VE +
Sbjct: 1202 ASLKKRHADSLAELE----GQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANA 1257
Query: 143 EVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQ 202
E ++ +L+ A L + L QK L +E E +L EEK+
Sbjct: 1258 EKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRL----------EEKE 1307
Query: 203 RKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLS 262
+L +E + ++E+L R Q E + K+ A LQ+ D E+ +
Sbjct: 1308 ALINQLSREKSNFTRQIEDL---RGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQE 1364
Query: 263 RTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQG 322
A LH + +Q ++ ED + +EL L + + +
Sbjct: 1365 VKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNA 1424
Query: 323 PSER 326
ER
Sbjct: 1425 SLER 1428
Score = 41.2 bits (95), Expect = 0.004
Identities = 68/283 (24%), Positives = 120/283 (42%), Gaps = 40/283 (14%)
Query: 85 IKEWFEESLSQVNHHSAASNETYQER---LARLEGDKESLILQV-------SVLTDQVEA 134
+K+ EE L+++ + +N E L +L+ + L +Q+ S L +QV
Sbjct: 1626 LKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAV 1685
Query: 135 QGEKIRDLEVCLE---GHQVKLNAAEEMLQQELLSRTS----LETQKLDLMTEVSELKLK 187
+ L+ LE Q + + ++ELL T TQ L+++ +L+
Sbjct: 1686 AERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEAD 1745
Query: 188 LVGMEKEQRE-------QEEKQRK----AEELLQELRHLKIKVEELENERNQYEWKLKAT 236
+ M+KE E EEK +K A L +EL+ + + LE R E +
Sbjct: 1746 VARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDL 1805
Query: 237 KAEVAQLQEQVALKDA--EIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLL---- 290
+ +A+ EQ+AL + +I++L S++ R E R E QR +E +
Sbjct: 1806 QKRLAE-AEQMALMGSRKQIQKLESRV-RELEGELEGEIRRSAEAQRGARRLERCIKELT 1863
Query: 291 -LANEDK---DRRIEELTGLLNQYRKVKEIVMVTQGPSERTLS 329
A EDK R ++ L + + K+ V V + + + LS
Sbjct: 1864 YQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLS 1906
Score = 40.4 bits (93), Expect = 0.007
Identities = 67/278 (24%), Positives = 113/278 (40%), Gaps = 50/278 (17%)
Query: 54 IEDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEE----------SLSQVNHHSAAS 103
IEDLR LE Q A Q ++E +EE +LS+VN
Sbjct: 1324 IEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQW 1383
Query: 104 NETYQERLARLEGDKESLILQVSV-LTDQVEAQG-EKIRDLEVCLEGHQVKL-------- 153
Y+ + + D E ++++ L + EA G R+ + HQ++L
Sbjct: 1384 RMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSD 1443
Query: 154 -----NAAEEMLQQELLSRTSL--------ETQKL---------DLMTEVSELKL----K 187
+AA + Q++L S +L E+Q L L TE+ +LK
Sbjct: 1444 LGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEES 1503
Query: 188 LVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQV 247
+VG E +RE + Q + L ++R + E+E + E + T+ +V + +
Sbjct: 1504 IVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEE--KTEVQVTLEETEG 1561
Query: 248 ALKDAEIERLHSQLS--RTAALHSESHTERDQEIQRLK 283
AL+ E + LH QL A +E+D+EI+ +
Sbjct: 1562 ALERNESKILHFQLELLEAKAELERKLSEKDEEIENFR 1599
Score = 39.7 bits (91), Expect = 0.012
Identities = 49/198 (24%), Positives = 85/198 (42%), Gaps = 36/198 (18%)
Query: 174 KLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELR---------------HLKIK 218
K+ + + SE+ ++ G+++E + ++ K+E +EL+ L+ +
Sbjct: 847 KIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAE 906
Query: 219 VEELENERNQYEWKLKA---TKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTER 275
E L N Q EW +K+ +A V +L E+V E E ++S+L+ + E
Sbjct: 907 QETLANVEEQCEWLIKSKIQLEARVKELSERV----EEEEEINSELTARGRKLEDECFEL 962
Query: 276 DQEIQRLKMGMETLLLANEDKDRR--------IEELTGLLNQYRKVKEIVMVTQGPSERT 327
+EI L ET+L+ +E + R EE+ L K+ V Q ++T
Sbjct: 963 KKEIDDL----ETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQT 1018
Query: 328 LS--INEEEPEGGFSKWN 343
L EEE SK N
Sbjct: 1019 LDDLHMEEEKLSSLSKAN 1036
Score = 33.1 bits (74), Expect = 1.2
Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 11/118 (9%)
Query: 108 QERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEG--HQVKLNAAEEMLQQELL 165
+ R+ LEG+ E I + EAQ R LE C++ +Q + + Q +
Sbjct: 1828 ESRVRELEGELEGEIRR------SAEAQ-RGARRLERCIKELTYQAEEDKKNLSRMQTQM 1880
Query: 166 SRTSLETQKLDLMTEVSELKLK--LVGMEKEQREQEEKQRKAEELLQELRHLKIKVEE 221
+ L+ Q EV+E + L +K+Q E E + +AE ++ LKIK E
Sbjct: 1881 DKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKARE 1938
>gi|109134347 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 59.3 bits (142), Expect = 2e-08
Identities = 64/283 (22%), Positives = 133/283 (46%), Gaps = 30/283 (10%)
Query: 54 IEDLRL--ALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERL 111
I D++L A EL +ER + S++ G ++ E + V HH E +E +
Sbjct: 323 ITDIKLETARAKSELERERNKIQSELDG-----LQSDNEILKAAVEHHKVLLVEKDRELI 377
Query: 112 ARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQEL-LSRTSL 170
+++ KE ++ VL D+ ++ DLE H V + ++ +++L S+ +
Sbjct: 378 RKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAE 437
Query: 171 ETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEEL---EN--- 224
E + +L + +L+ ++V +E ++E+ E +L Q++ L+I+V L EN
Sbjct: 438 EITRKELQSVRLKLQQQIVTIENAEKEKNEN----SDLKQQISSLQIQVTSLAQSENDLL 493
Query: 225 ----------ERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHS--QLSRTAALHSESH 272
ER + E + ++AE AQL+ + L++ +I+ L +L E +
Sbjct: 494 NSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLHERITDREEKY 553
Query: 273 TERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKE 315
+ +++QR + + +E+K +R++E +L ++ E
Sbjct: 554 NQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEVLEAKKEELE 596
Score = 41.2 bits (95), Expect = 0.004
Identities = 59/286 (20%), Positives = 119/286 (41%), Gaps = 51/286 (17%)
Query: 75 SQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEA 134
S + G + + K +E L + HH A + +T + RL+ + L ++ L ++ +
Sbjct: 22 SGLTGSQSEFQKMLIDERL-RCEHHKA-NYQTLKAEHTRLQNEHVKLQNELKHLFNEKQT 79
Query: 135 QGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEV------------- 181
Q EK++ L L G V+ E ++ ++L+ LE + + E+
Sbjct: 80 QQEKLQLLLEELRGELVEKTKDLEEMKLQILTPQKLELLRAQIQQELETPMRERFRNLDE 139
Query: 182 ---------SELKLKLVGMEKEQREQEEK-------------------QRKAEELLQELR 213
++L+ + ++ E Q+E+ + EEL +L
Sbjct: 140 EVEKYRAVYNKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLL 199
Query: 214 HLKI-----KVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALH 268
++ + +VE+L E+ KLK +AEVA+L+ + +A++E ++Q + L
Sbjct: 200 NVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVE--NAQRIQVRQLA 257
Query: 269 SESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVK 314
T R E ++ + L E + E+ T L+N+ K +
Sbjct: 258 EMQATVRSLEAEKQSANLRAERLEKELQSSS-EQNTFLINKLHKAE 302
>gi|109134355 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 59.3 bits (142), Expect = 2e-08
Identities = 64/283 (22%), Positives = 133/283 (46%), Gaps = 30/283 (10%)
Query: 54 IEDLRL--ALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERL 111
I D++L A EL +ER + S++ G ++ E + V HH E +E +
Sbjct: 323 ITDIKLETARAKSELERERNKIQSELDG-----LQSDNEILKAAVEHHKVLLVEKDRELI 377
Query: 112 ARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQEL-LSRTSL 170
+++ KE ++ VL D+ ++ DLE H V + ++ +++L S+ +
Sbjct: 378 RKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAE 437
Query: 171 ETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEEL---EN--- 224
E + +L + +L+ ++V +E ++E+ E +L Q++ L+I+V L EN
Sbjct: 438 EITRKELQSVRLKLQQQIVTIENAEKEKNEN----SDLKQQISSLQIQVTSLAQSENDLL 493
Query: 225 ----------ERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHS--QLSRTAALHSESH 272
ER + E + ++AE AQL+ + L++ +I+ L +L E +
Sbjct: 494 NSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLHERITDREEKY 553
Query: 273 TERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKE 315
+ +++QR + + +E+K +R++E +L ++ E
Sbjct: 554 NQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEVLEAKKEELE 596
Score = 41.2 bits (95), Expect = 0.004
Identities = 59/286 (20%), Positives = 119/286 (41%), Gaps = 51/286 (17%)
Query: 75 SQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEA 134
S + G + + K +E L + HH A + +T + RL+ + L ++ L ++ +
Sbjct: 22 SGLTGSQSEFQKMLIDERL-RCEHHKA-NYQTLKAEHTRLQNEHVKLQNELKHLFNEKQT 79
Query: 135 QGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEV------------- 181
Q EK++ L L G V+ E ++ ++L+ LE + + E+
Sbjct: 80 QQEKLQLLLEELRGELVEKTKDLEEMKLQILTPQKLELLRAQIQQELETPMRERFRNLDE 139
Query: 182 ---------SELKLKLVGMEKEQREQEEK-------------------QRKAEELLQELR 213
++L+ + ++ E Q+E+ + EEL +L
Sbjct: 140 EVEKYRAVYNKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLL 199
Query: 214 HLKI-----KVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALH 268
++ + +VE+L E+ KLK +AEVA+L+ + +A++E ++Q + L
Sbjct: 200 NVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVE--NAQRIQVRQLA 257
Query: 269 SESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVK 314
T R E ++ + L E + E+ T L+N+ K +
Sbjct: 258 EMQATVRSLEAEKQSANLRAERLEKELQSSS-EQNTFLINKLHKAE 302
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 58.9 bits (141), Expect = 2e-08
Identities = 58/235 (24%), Positives = 116/235 (49%), Gaps = 40/235 (17%)
Query: 86 KEWFEESLSQVNHHSAASN----------ETYQERLARLEGDKESLILQVSVLTDQVEAQ 135
KE ++ LS+ H A+ + +E LAR +KE+L+ + + L +++A
Sbjct: 689 KEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAV 748
Query: 136 GEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQ 195
+DL L+G L++A+E+L+ L E Q+ + + EV++ +L++
Sbjct: 749 ERDRQDLAEQLQG----LSSAKELLESSL-----FEAQQQNSVIEVTKGQLEV------- 792
Query: 196 REQEEKQRKAEELLQ-ELRHLKIKVEELENERNQYEWKLKATKAEVAQ--------LQEQ 246
Q + +A+E++Q E+R LK+ EL+ ER+Q E + A ++AQ L++Q
Sbjct: 793 --QIQTVTQAKEVIQGEVRCLKL---ELDTERSQAEQERDAAARQLAQAEQEGKTALEQQ 847
Query: 247 VALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIE 301
A + E+ +L + + + H + + + ++R KM +E L + + I+
Sbjct: 848 KAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQ 902
Score = 51.6 bits (122), Expect = 3e-06
Identities = 89/389 (22%), Positives = 156/389 (40%), Gaps = 85/389 (21%)
Query: 57 LRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNE---TYQERLAR 113
L+L E +E +ERA L + G + +E+L+ + A E T + ++
Sbjct: 1388 LKLKNEEVESERERAQALQE-QGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQE 1446
Query: 114 LEGDKES-------LILQVSVLTDQVEAQGEKIRDLEVC----------LEGHQVKLNAA 156
LE +E L L + +V+ Q E+I++LE C ++ + KL
Sbjct: 1447 LEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQ 1506
Query: 157 EEML---------QQELLSRTSLETQKLDLMTE-----VSELKLKLVGMEKEQREQEEKQ 202
E + Q+ +L LE +K D M E V +LK +LV +E E EE
Sbjct: 1507 REQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENH 1566
Query: 203 RKAE---ELLQELR-----------HLKIKVEELENERNQYEWKLKATKAEVAQLQEQVA 248
K E +L++EL HL + +EE E L+A +++ L+
Sbjct: 1567 HKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQE-------LQAQSSQIHDLESHST 1619
Query: 249 LKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLN 308
+ E++ ++ +S E+ +E+QR K + +D +RR +EL
Sbjct: 1620 VLARELQERDQEV--------KSQREQIEELQRQKEHL------TQDLERRDQEL----- 1660
Query: 309 QYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGP 368
KE + V + R I EE+ E K + + E ++++ + GP
Sbjct: 1661 --MLQKERIQVLEDQRTRQTKILEEDLEQ--IKLSLRERGRELTTQRQLMQERAEEGKGP 1716
Query: 369 PPLPQKSLE------TRAQKKLSCSLEDL 391
+ SLE +K++ C E +
Sbjct: 1717 SKAQRGSLEHMKLILRDKEKEVECQQEHI 1745
Score = 49.7 bits (117), Expect = 1e-05
Identities = 72/327 (22%), Positives = 141/327 (43%), Gaps = 64/327 (19%)
Query: 55 EDLRLALEMLELPQERAALLS---QIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERL 111
E+LR LE+LE R ++ Q+ G +A KE +E L H + E QE L
Sbjct: 473 EELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEEL----HLAVRERERLQEML 528
Query: 112 ARLEGDKESLILQVSVLTDQVEA---QGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRT 168
LE + + ++ L + +E+ +GE +R + + L AE+ + + S
Sbjct: 529 MGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTA---ALARAEQSIAELSSSEN 585
Query: 169 SLETQKLDLMTEVSELK-------LKLVGMEKE--QREQE-------------------- 199
+L+T+ DL +L L VG+ ++ Q E+E
Sbjct: 586 TLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQV 645
Query: 200 ---EKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVA-------L 249
E +++ E L ++ HL+ ++++ E + + L+ + E ++Q++++
Sbjct: 646 DLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEA 705
Query: 250 KDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANE-DKDRRIEELTGL-- 306
++E+LH + R + + + E+ + + R K +E L A E D+ E+L GL
Sbjct: 706 ATTQLEQLHQEAKRQEEVLARAVQEK-EALVREKAALEVRLQAVERDRQDLAEQLQGLSS 764
Query: 307 --------LNQYRKVKEIVMVTQGPSE 325
L + ++ ++ VT+G E
Sbjct: 765 AKELLESSLFEAQQQNSVIEVTKGQLE 791
Score = 48.9 bits (115), Expect = 2e-05
Identities = 73/298 (24%), Positives = 123/298 (41%), Gaps = 39/298 (13%)
Query: 59 LALEMLELPQERAALLSQIPG------PTAAYIKEWFEESLSQVNHHSAASNETYQERLA 112
L L++ E QE A SQI A ++E +E SQ + +E L
Sbjct: 1593 LTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQ--REQIEELQRQKEHLT 1650
Query: 113 R-LEGDKESLILQ---VSVLTDQVEAQG----EKIRDLEVCLEGHQVKLNAAEEMLQQEL 164
+ LE + L+LQ + VL DQ Q E + +++ L +L +++Q+
Sbjct: 1651 QDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERA 1710
Query: 165 --------LSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLK 216
R SLE KL L + E+ E +Q E Q ++L Q+L+ L
Sbjct: 1711 EEGKGPSKAQRGSLEHMKLILRDKEKEV-------ECQQEHIHELQELKDQLEQQLQGLH 1763
Query: 217 IKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERD 276
KV E +Q E ++ + ++ + +EQ LK+ ++ + R A +RD
Sbjct: 1764 RKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALA-------QRD 1816
Query: 277 QEIQRLKMGMETLLLANEDKDRRIEELTGLLNQ-YRKVKEIVMVTQGPSERTLSINEE 333
QE++ L+ + E + + L G L Q + +KE Q E+ + EE
Sbjct: 1817 QELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEE 1874
Score = 48.5 bits (114), Expect = 3e-05
Identities = 62/254 (24%), Positives = 112/254 (44%), Gaps = 41/254 (16%)
Query: 108 QERLARLEGDKESLILQVSVLTDQVEAQGEK--------------IRDLEVCLEGHQVKL 153
+ERL E +K + ++ L Q+ E+ + +L + Q +L
Sbjct: 1270 EERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRL 1329
Query: 154 NAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELR 213
AE + R L+ K +L +V L+ +V E R Q EE L+ R
Sbjct: 1330 RRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVV----EARAQASAAGILEEDLRTAR 1385
Query: 214 H-LKIKVEELENERNQYEWKLKATKAEVAQ---LQEQVAL-------KDAEIERLHSQLS 262
LK+K EE+E+ER + + + + +VAQ LQE +AL ++ E+E L Q+
Sbjct: 1386 SALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQI- 1444
Query: 263 RTAALHSESHTERDQEIQRLKMGMETLLL--ANEDKDRRIEELTGLLNQYRKVKEIVMVT 320
E+ +E+Q+ + + +L L N++ D + E++ L + R V E + +
Sbjct: 1445 --------QELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQE-LEKCRSVLEHLPMA 1495
Query: 321 QGPSERTLSINEEE 334
E+ L++ E+
Sbjct: 1496 VQEREQKLTVQREQ 1509
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/176 (24%), Positives = 76/176 (43%), Gaps = 11/176 (6%)
Query: 109 ERLARLEGDKESLILQVSVLTDQVEAQ-GEKIRDLEVCLEGHQVKLNAAEEMLQQELLSR 167
++L RL D + L+ T ++ Q E R+L+ H+ L A +E
Sbjct: 946 QQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQE-------ES 998
Query: 168 TSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERN 227
+SL K+DL +V +LK +LV + QR E+ + +E L+E + +ELE E+
Sbjct: 999 SSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQ---EVQEKLRETQEYNRIQKELEREKA 1055
Query: 228 QYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLK 283
L + + LQE +++ E+ L + E + + Q +K
Sbjct: 1056 SLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVK 1111
Score = 45.8 bits (107), Expect = 2e-04
Identities = 94/411 (22%), Positives = 167/411 (40%), Gaps = 95/411 (23%)
Query: 55 EDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARL 114
E L + + + ++R L Q+ G ++A KE E SL + Q++ + +
Sbjct: 737 EKAALEVRLQAVERDRQDLAEQLQGLSSA--KELLESSLFEA-----------QQQNSVI 783
Query: 115 EGDKESLILQVSVLTDQVEAQGEKIRDLEVCLE-----GHQVKLNAAEEMLQQELLSRTS 169
E K L +Q+ +T E ++R L++ L+ Q + AA ++ Q E +T+
Sbjct: 784 EVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTA 843
Query: 170 LETQKLDLMTEVSELKLK---------------LVGMEKE-------------------- 194
LE QK EV++L+ K L +E+E
Sbjct: 844 LEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQA 903
Query: 195 QREQEEKQRKA-----------------EELLQELRHLKIKVEELENERNQYE-WKLKAT 236
QRE+E Q ++ E LLQ + L ++LE R + KLK
Sbjct: 904 QREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQ 963
Query: 237 KAE-VAQLQEQVALKDAEIERLHSQLSRTAALHSESHT--ERDQEIQRLKMGMETLLLAN 293
+ + Q Q Q A ++ + E AAL ES + + ++Q+ +++ L+A
Sbjct: 964 ETTGILQTQLQEAQRELK-EAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQ 1022
Query: 294 EDKDRRIE-ELTGLLNQYRKVKEIVM-VTQGPSERTLSINEEEPEGGFSKWNATNKDPEE 351
+D R +E E+ L + ++ I + + + TLS+ E+E ++ +
Sbjct: 1023 DDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQR------LLVLQEADS 1076
Query: 352 LFKQEMPPRCSSPTVGPPPLPQKSLETRA-QKKLSCSLEDLRSESVDKCMD 401
+ +QE+ L Q E + QK+LS +E LR E +K D
Sbjct: 1077 IRQQEL-----------SALRQDMQEAQGEQKELSAQMELLRQEVKEKEAD 1116
Score = 44.7 bits (104), Expect = 4e-04
Identities = 70/294 (23%), Positives = 119/294 (40%), Gaps = 37/294 (12%)
Query: 68 QERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSV 127
+E+ +L I T ++E + + +S + + + + DK +L L SV
Sbjct: 336 EEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADK-ALTLVRSV 394
Query: 128 LTDQVEAQGEKIRDLEVCLEGHQVKLN--------------AAEEMLQQELLSRTSLETQ 173
LT + +A ++DL L G Q +N A + LQ+ R +L Q
Sbjct: 395 LTRRRQA----VQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQ 450
Query: 174 KLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKL 233
+DL EV L +E+E Q+ EEL Q+L L+ + L + + +
Sbjct: 451 TVDLQGEVDSLS----------KERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQG 500
Query: 234 KATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLAN 293
+ + + + QE++ L E ERL L A SES + E+ L+ +E+ L
Sbjct: 501 DSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLS----ELITLREALESSHLEG 556
Query: 294 EDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNK 347
E + E+T L + E + SE TL + K +A N+
Sbjct: 557 ELLRQEQTEVTAALAR----AEQSIAELSSSENTLKTEVADLRAAAVKLSALNE 606
Score = 38.1 bits (87), Expect = 0.036
Identities = 55/221 (24%), Positives = 89/221 (40%), Gaps = 28/221 (12%)
Query: 89 FEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQV------EAQGEKIRDL 142
++E + Q+ A +E + + R + ++SL +V Q E + E+IR L
Sbjct: 2033 YQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGL 2092
Query: 143 EVCLEGHQVKLNAAEEMLQQ--ELLSRTSLETQKLDLMTE-VSELKLKLVGMEKEQREQE 199
+ Q+ L E+ + + E R +LE T + E LKL +E
Sbjct: 2093 HQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRL---- 2148
Query: 200 EKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQE-------QVALKDA 252
QR+ E L LR + + E + L TKA V+ LQE V +D+
Sbjct: 2149 --QRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDS 2206
Query: 253 EIERLHSQLSRT------AALHSESHTERDQEIQRLKMGME 287
E +RL +L T LHS T + R + G++
Sbjct: 2207 EQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQ 2247
Score = 32.7 bits (73), Expect = 1.5
Identities = 54/227 (23%), Positives = 90/227 (39%), Gaps = 22/227 (9%)
Query: 68 QERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSV 127
QE+A L Q A E +L + A + + L L + +S Q
Sbjct: 1899 QEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEA 1958
Query: 128 LTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLK 187
+ EA E + L+G + + +L+Q LSR SLE L + +
Sbjct: 1959 ARARAEALQEALGKAHAALQGKE------QHLLEQAELSR-SLEASTATLQASLDACQAH 2011
Query: 188 LVGMEKEQREQE-----EKQRKAEELLQELRHLKIKVEEL--ENERNQYEWKLKATKAEV 240
+E+ R QE + R E++ Q + L + EEL + ER Q K A + +
Sbjct: 2012 SRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQE 2071
Query: 241 AQLQEQVAL----KDAEIERLHSQLSRTAALHSESHTERDQEIQRLK 283
+QE+ L ++ EI LH + + +++QEI L+
Sbjct: 2072 NMIQEKQNLGQEREEEEIRGLHQSVRELQL----TLAQKEQEILELR 2114
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 58.9 bits (141), Expect = 2e-08
Identities = 73/318 (22%), Positives = 137/318 (43%), Gaps = 24/318 (7%)
Query: 105 ETYQERLARLE---------GDKESLIL-QVSVLTDQVEAQGEK----IRDLEVCLEGHQ 150
+ Y+E L+++E G+ +++ L Q+ ++ DQ + + EK +++LE +
Sbjct: 993 DQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTE 1052
Query: 151 VKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQ 210
+L E LQ+ + T L+ +L + + +L+ ++K Q EEK ++L
Sbjct: 1053 TELT---EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTA 1109
Query: 211 ELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSE 270
ELR K+++E+ + E + + LK E+ Q QV D I ++ +
Sbjct: 1110 ELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEG 1169
Query: 271 SHTERDQEIQRLKMGMETL--LLANEDKDRRIEELTGLLNQY---RKVKEIVMVTQGPSE 325
+ + + E++ +E+L L N + R +E L N+ + KEI Q E
Sbjct: 1170 TLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKE 1229
Query: 326 RTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKSLETRAQKKLS 385
+ E+E A + E +E +S T Q+ R ++LS
Sbjct: 1230 MESVMKEQEQYIATQYKEAIDLGQELRLTREQVQ--NSHTELAEARHQQVQAQREIERLS 1287
Query: 386 CSLEDLRSESVDKCMDGN 403
LED++ S +K GN
Sbjct: 1288 SELEDMKQLSKEKDAHGN 1305
Score = 54.7 bits (130), Expect = 4e-07
Identities = 73/351 (20%), Positives = 151/351 (43%), Gaps = 30/351 (8%)
Query: 90 EESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGH 149
EE L + + N+ QER + + E L ++ L ++ EK+R + V
Sbjct: 388 EEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEV 447
Query: 150 QVKLNAAEEM---LQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKE----QREQEEKQ 202
+L + + L+ EL ++ + K LM E ELK+++ + Q+E E +
Sbjct: 448 MAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSR 507
Query: 203 ---RKAEELLQEL---RHL--------KIKVEELENERNQYEWKLKATKAEVAQLQEQVA 248
R E+++ +L R L K ++ N+ ++ +A K +++L+ ++A
Sbjct: 508 VELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLA 567
Query: 249 LKDAEIERLHSQLSRTAALHSESHTERDQEIQRL-KMGMETLLLANEDKDRRIEELTGLL 307
+K+AEI++LH+ L+ S QE +L + E + L +++
Sbjct: 568 IKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQHT 627
Query: 308 NQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPE-ELFKQEMPPRCSSPTV 366
+ KE + G E + + E E K N ++ + +L ++E+ + S+ +
Sbjct: 628 MNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSK 687
Query: 367 GPPPLPQK-----SLETRAQKKLSC--SLEDLRSESVDKCMDGNQPFPVLE 410
+ +K +LE + ++K+ S+ +E + M+ N+ LE
Sbjct: 688 LESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLE 738
Score = 47.8 bits (112), Expect = 5e-05
Identities = 55/248 (22%), Positives = 103/248 (41%), Gaps = 49/248 (19%)
Query: 108 QERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLE---VCLEGHQVKLNAAEEMLQQEL 164
+ + +L + + L S++T + K+ LE V L GHQV + + Q +
Sbjct: 570 EAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAESVKD---QNQH 626
Query: 165 LSRTSLETQKLDLMTEVSELKLKLVGMEKEQRE---------------QEEKQRKAEELL 209
E ++ L+T + EL+ KL+ +E E + QEE KA
Sbjct: 627 TMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSS 686
Query: 210 QELRHLKIKVEELENERNQYEWKLKATK---AEVAQLQEQVALKDAEIERLHSQLS---- 262
+ + K +L Q E K+ A A+ A+L++++ K+ +I L + ++
Sbjct: 687 KLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHE 746
Query: 263 -------RTAALHSESHTERDQEIQRLKMGME-----------TLLLANED---KDRRIE 301
+ +H E H E +++I+RL+ +E T+ + +D K +E
Sbjct: 747 KICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLE 806
Query: 302 ELTGLLNQ 309
L LL +
Sbjct: 807 SLDRLLTE 814
Score = 45.8 bits (107), Expect = 2e-04
Identities = 55/256 (21%), Positives = 109/256 (42%), Gaps = 28/256 (10%)
Query: 90 EESLSQVNHHSAASNETYQERLARLEGDKESLILQ----VSVLTDQVEAQGEKIRDLEVC 145
E L + N + N+ Q +L +KE ++LQ +S L ++E ++++++E
Sbjct: 1175 ELELKECNKQIESLNDKLQNAKEQLR-EKEFIMLQNEQEISQLKKEIERTQQRMKEMESV 1233
Query: 146 LEGHQ----VKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEK 201
++ + + A ++ Q+ L+R ++ TE++E + +Q +
Sbjct: 1234 MKEQEQYIATQYKEAIDLGQELRLTREQVQNSH----TELAEAR----------HQQVQA 1279
Query: 202 QRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQL----QEQVALKDAEIERL 257
QR+ E L EL +K +E + N +L A+K A L Q ++ AE+E L
Sbjct: 1280 QREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESL 1339
Query: 258 HSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLL-NQYRKVKEI 316
H E+H + K ++ L E +EE + N +++V++
Sbjct: 1340 KEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDR 1399
Query: 317 VMVTQGPSERTLSINE 332
V + +E L+ E
Sbjct: 1400 NEVIEAANEALLTKGE 1415
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/262 (22%), Positives = 114/262 (43%), Gaps = 32/262 (12%)
Query: 43 SYMNPFPVLHL-IEDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSA 101
S M F +H + R + MLE Q++AA + + EE + + +
Sbjct: 254 SLMTKFESIHFELTQSRAKVSMLESAQQQAASVPIL------------EEQIINLEAEVS 301
Query: 102 ASNETYQERLARLEGDKESLI-LQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEML 160
A ++ +E +LE ++ +I + S+ + E K+ LE +G + + E +
Sbjct: 302 AQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALY 361
Query: 161 QQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVE 220
E LS+ + +K +V+E +EK Q E+E +R +E + L+ +
Sbjct: 362 NAEELSKAFQQYKK-----KVAEK------LEKVQAEEEILERNLTNCEKENKRLQERCG 410
Query: 221 ELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQL--SRTAALHSESHTERDQE 278
++E + KL+ K E +E++ + + + +QL SR + L ES E E
Sbjct: 411 LYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDE 470
Query: 279 IQRLKMGMETLLLANEDKDRRI 300
I R K L NE+++ ++
Sbjct: 471 ILRDKFS-----LMNENRELKV 487
Score = 42.0 bits (97), Expect = 0.002
Identities = 55/238 (23%), Positives = 102/238 (42%), Gaps = 28/238 (11%)
Query: 102 ASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQ 161
+S+ + + L L Q + L Q + K + L + K++ E Q
Sbjct: 222 SSSAPVDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESA-Q 280
Query: 162 QELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRH--LKIKV 219
Q+ S LE Q ++L EVS L E + + ++ + E+ LQE + +K+KV
Sbjct: 281 QQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKV 340
Query: 220 EELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEI 279
+ LE + + + A+ Q AL +AE +LS+ + + E+ +++
Sbjct: 341 DLLEQTK----------QGKRAERQRNEALYNAE------ELSKAFQQYKKKVAEKLEKV 384
Query: 280 QRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEG 337
Q + +E L E +++R++E GL Y+ EI+ E+ + EE G
Sbjct: 385 QAEEEILERNLTNCEKENKRLQERCGL---YKSELEIL------KEKLRQLKEENNNG 433
Score = 37.0 bits (84), Expect = 0.080
Identities = 41/196 (20%), Positives = 83/196 (42%), Gaps = 11/196 (5%)
Query: 98 HHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL----EVCLEGHQVKL 153
HH + + E ++ + + L +QV + K+R L E+C E + L
Sbjct: 803 HHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHL 862
Query: 154 NAAEEMLQ--QELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQE 211
N E + ++ L + S E L ELK+K +++ + Q ++ Q
Sbjct: 863 NQLEGNKEKFEKQLKKKSEEVYCLQ-----KELKIKNHSLQETSEQNVILQHTLQQQQQM 917
Query: 212 LRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSES 271
L+ I+ ELE+ + + E ++ + E+ + +E A K ++E + A L +
Sbjct: 918 LQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQK 977
Query: 272 HTERDQEIQRLKMGME 287
E +++K+ M+
Sbjct: 978 VIELTGTARQVKIEMD 993
>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
Length = 1113
Score = 58.5 bits (140), Expect = 3e-08
Identities = 57/229 (24%), Positives = 110/229 (48%), Gaps = 21/229 (9%)
Query: 108 QERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSR 167
+ ++A ++G ESL +VS LT Q+E+ E +R + L ++ L ++E +
Sbjct: 447 ERQMAAIQGKNESLE-KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTIS------ 499
Query: 168 TSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERN 227
DL T + E K +E E + + + + LQEL+HLK + + L N +
Sbjct: 500 --------DLTTSLQE---KERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQT 548
Query: 228 QYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGME 287
+ E LK E ++ E + + + +L Q RTA + ++EI +M ++
Sbjct: 549 ECE-ALKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRMELK 607
Query: 288 TLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPE 336
L + + KD +I EL ++ +++++ +V G SER ++ + + E
Sbjct: 608 ELKILKDKKDAKIRELEARVSDL-ELEKVKLVNAG-SERLRAVKDIKQE 654
Score = 48.1 bits (113), Expect = 3e-05
Identities = 53/257 (20%), Positives = 118/257 (45%), Gaps = 41/257 (15%)
Query: 85 IKEWFEESLSQVNHH--SAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL 142
+++ E V H +A + + + +L + D+ + ++ +L D+ +A KIR+L
Sbjct: 567 LRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRMELKELKILKDKKDA---KIREL 623
Query: 143 EVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQ 202
E A L+ E + + +++L + ++ + + +L+ K R +
Sbjct: 624 E-----------ARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRSELNNL 672
Query: 203 RKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQ-------------------- 242
+ E+L+ R+ + K EE+E N+ + +LK+ ++E+ Q
Sbjct: 673 SEEYEVLK--RNFRNKSEEMEMTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAM 730
Query: 243 -LQEQVALKDAEIERLHSQLSRTAALHSESHTERD-QEIQRLKMGMETLLLANEDKDRRI 300
+Q+Q+ K +I+ L S++ + ++ E+ + ++ K+ E +A E K++
Sbjct: 731 GMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKSKLSQELSTVATE-KNKMA 789
Query: 301 EELTGLLNQYRKVKEIV 317
EL L +Q R++KE V
Sbjct: 790 GELEVLRSQERRLKEKV 806
Score = 41.6 bits (96), Expect = 0.003
Identities = 44/207 (21%), Positives = 94/207 (45%), Gaps = 21/207 (10%)
Query: 104 NETYQERLARLEGDKESLILQV-SVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQ 162
+ T E+L ++ E ++ ++ S+L D EA G+KI + + H L +A + +
Sbjct: 168 SNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKICEHDSMSTLHFRSLGSAISKILR 227
Query: 163 ELLSRTSLETQKLDLMTEVSELKLKLVGMEKE-QREQEEKQRKAEELLQELRHLKIKVEE 221
E L TE+S LK ++ +E + + + E Q K E LLQ+ + ++E+
Sbjct: 228 E-------------LDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQD---RIEQ 271
Query: 222 LENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQR 281
L +E +E ++ + + + Q +++E + Q +++ ++ + + +
Sbjct: 272 LISE---HEVEITGLTEKASSARSQANSIQSQMEIIQEQARNQNSMYMRQLSDLESTVSQ 328
Query: 282 LKMGMETLLLANEDKDRRIEELTGLLN 308
L+ + EDK +E+ L N
Sbjct: 329 LRSELREAKRMYEDKTEELEKQLVLAN 355
Score = 32.7 bits (73), Expect = 1.5
Identities = 45/218 (20%), Positives = 95/218 (43%), Gaps = 20/218 (9%)
Query: 65 ELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQ 124
++ QER LL+++ + L+ ++ ++ + +E L +Q
Sbjct: 650 DIKQERDQLLNEV---------KTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNKLKMQ 700
Query: 125 VSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSEL 184
+ ++E ++ +E +GH +K+ A M +Q R ++ L +++ L
Sbjct: 701 LKSAQSELEQTRNTLKSMEGS-DGHAMKV--AMGMQKQITAKRGQIDA----LQSKIQFL 753
Query: 185 KLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVE-ELENERNQYE-WKLKATKAEVAQ 242
+ + KE+ +E++ K + L + K K+ ELE R+Q K K T EVA
Sbjct: 754 EEAMTNANKEKHFLKEEKSKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVTNMEVAL 813
Query: 243 LQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQ 280
++ +L+ AE + + + + + HT +E+Q
Sbjct: 814 --DKASLQFAECQDIIQRQEQESVRLKLQHTLDIKELQ 849
Score = 32.3 bits (72), Expect = 2.0
Identities = 44/215 (20%), Positives = 87/215 (40%), Gaps = 26/215 (12%)
Query: 87 EWFEESLSQVN---HHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLE 143
++ EE+++ N H + L+ + +K + ++ VL Q EK+ ++E
Sbjct: 751 QFLEEAMTNANKEKHFLKEEKSKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVTNME 810
Query: 144 VCLEGHQVKLNAAEEMLQQELLSRTSLETQ-KLDL-------MTEVSELKLKLVGMEKEQ 195
V L+ ++ ++++Q++ L+ Q LD+ T S LK +L+
Sbjct: 811 VALDKASLQFAECQDIIQRQEQESVRLKLQHTLDIKELQGPGYTSNSSLKPRLLQPASVT 870
Query: 196 REQ-------------EEKQRKAEELLQE-LRHLKIKVEELENERNQYEWKLKATKAEVA 241
R KA L ++ R LK ++EL + N+ E + +K E
Sbjct: 871 RSHSNVPSSQSTASFLSHHSTKANTLKEDPTRDLKQLLQELRSVINE-EPAVSLSKTEED 929
Query: 242 QLQEQVALKDAEIERLHSQLSRTAALHSESHTERD 276
AL+D + + R+ H +++ RD
Sbjct: 930 GRTSLGALEDRVRDCITESSLRSDMCHRSNNSLRD 964
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 58.5 bits (140), Expect = 3e-08
Identities = 61/258 (23%), Positives = 119/258 (46%), Gaps = 42/258 (16%)
Query: 54 IEDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLAR 113
I+DL L L +E +E+ A +++ T +E++++++ A ET+Q+ L
Sbjct: 957 IDDLELTLAKVE--KEKHATENKVKNLTEEMAG--LDETIAKLSKEKKALQETHQQTLDD 1012
Query: 114 LEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQ 173
L+ +++ +V++LT +++ DLE LE QE R LE
Sbjct: 1013 LQAEED----KVNILTKAKTKLEQQVDDLEGSLE--------------QEKKLRMDLERA 1054
Query: 174 KLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKL 233
K L ++ + + ME ++++ +EK K E E+ +L K+E+ + Q + K+
Sbjct: 1055 KRKLEGDLKLAQESTMDMENDKQQLDEKLEKKE---FEISNLISKIEDEQAVEIQLQKKI 1111
Query: 234 KATKAEVAQLQEQVALK---DAEIERLHSQLSR--------------TAALHSESHTERD 276
K +A + +L E++ + A+ E+ S LSR + E + +R+
Sbjct: 1112 KELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKRE 1171
Query: 277 QEIQRLKMGMETLLLANE 294
E Q+L+ +E L +E
Sbjct: 1172 AEFQKLRRDLEEATLQHE 1189
Score = 52.0 bits (123), Expect = 2e-06
Identities = 44/194 (22%), Positives = 87/194 (44%), Gaps = 7/194 (3%)
Query: 90 EESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGH 149
EE + VN A+ +T Q RL+ + E L+L V A +K R+ + L
Sbjct: 1404 EEHVEAVNAKCASLEKTKQ----RLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEW 1459
Query: 150 QVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELL 209
+ K + L+ SL T+ + E L +E +RE + Q++ +L
Sbjct: 1460 KQKYEETQAELEASQKESRSLSTELFKVKNVYEE---SLDQLETLRRENKNLQQEISDLT 1516
Query: 210 QELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHS 269
+++ ++ ELE + Q E + +A + + + + ++ +I R+ +L++ +
Sbjct: 1517 EQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD 1576
Query: 270 ESHTERDQEIQRLK 283
E+D+EI +LK
Sbjct: 1577 RKIAEKDEEIDQLK 1590
Score = 50.4 bits (119), Expect = 7e-06
Identities = 54/232 (23%), Positives = 107/232 (46%), Gaps = 36/232 (15%)
Query: 83 AYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDL 142
A +KE F+++ ++ S A + +E++ L +K L LQV +++ + + D
Sbjct: 853 ATMKEEFQKTKDELAK-SEAKRKELEEKMVTLLKEKNDLQLQV-------QSEADSLAD- 903
Query: 143 EVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQ 202
AEE +Q + ++ LE + + EV+E E+E+ E
Sbjct: 904 -------------AEERCEQLIKNKIQLEAK----IKEVTERA------EEEEEINAELT 940
Query: 203 RKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLS 262
K +L E LK +++LE + E + AT+ +V L E++A D I ++LS
Sbjct: 941 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETI----AKLS 996
Query: 263 RTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVK 314
+ E+H + ++Q + + L A ++++++L G L Q +K++
Sbjct: 997 KEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLR 1048
Score = 47.8 bits (112), Expect = 5e-05
Identities = 49/202 (24%), Positives = 94/202 (46%), Gaps = 11/202 (5%)
Query: 111 LARLEGDKESLILQVSVLTDQVEAQGEKIRDL----EVCLEGHQVKLN---AAEEMLQQE 163
LA++E +K + +V LT+++ E I L + E HQ L+ A E+ +
Sbjct: 964 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNIL 1023
Query: 164 LLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRH----LKIKV 219
++T LE Q DL + + K + +E+ +R+ E + A+E ++ + L K+
Sbjct: 1024 TKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKL 1083
Query: 220 EELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEI 279
E+ E E + K++ +A QLQ+++ A IE L ++ A +++ +R
Sbjct: 1084 EKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLS 1143
Query: 280 QRLKMGMETLLLANEDKDRRIE 301
+ L+ E L A ++E
Sbjct: 1144 RELEEISERLEEAGGATSAQVE 1165
Score = 43.9 bits (102), Expect = 7e-04
Identities = 62/258 (24%), Positives = 112/258 (43%), Gaps = 28/258 (10%)
Query: 105 ETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQEL 164
E +E+LA +E L ++ L +E Q E+ R + + +L A E +Q
Sbjct: 1668 EDLKEQLAIVERRANLLQAEIEELWATLE-QTERSRKIA------EQELLDASERVQLLH 1720
Query: 165 LSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRK----AEELLQELRHLKIKVE 220
TSL K L +VS+L+ ++ + +E R EEK +K A + +EL+ +
Sbjct: 1721 TQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSA 1780
Query: 221 ELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQ 280
LE + E +K + + + EQ+ALK + +++ +R L E E+ + +
Sbjct: 1781 HLERMKKNLEQTVKDLQHRLDE-AEQLALKGGK-KQIQKLEARVRELEGEVENEQKRNAE 1838
Query: 281 RLKMGMETLLLANEDKDRRIEELTGLLNQYRK----VKEIVMVTQG---PSERTLSINEE 333
+K +RR++ELT + RK ++++V Q +R EE
Sbjct: 1839 AVK--------GLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEE 1890
Query: 334 EPEGGFSKWNATNKDPEE 351
+ SK+ + EE
Sbjct: 1891 QSNANLSKFRKLQHELEE 1908
Score = 37.0 bits (84), Expect = 0.080
Identities = 72/313 (23%), Positives = 121/313 (38%), Gaps = 66/313 (21%)
Query: 69 ERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASN--------------------ETYQ 108
E+ AL+SQ+ A ++ EE Q+ + A N E Q
Sbjct: 1296 EKDALVSQLSRSKQASTQQ-IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQ 1354
Query: 109 ERLARLEGDKESLILQVSVLTDQVEAQG-EKIRDLEVCLEGHQVKLNAAEEMLQQELLSR 167
E A L+ +V+ + E ++ +LE + +L AEE ++
Sbjct: 1355 EGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKC 1414
Query: 168 TSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENE-- 225
SLE K L EV +L L + ++KQR +++L E K K EE + E
Sbjct: 1415 ASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSE---WKQKYEETQAELE 1471
Query: 226 ----------------RNQYEWKL----------KATKAEVAQLQEQVA---LKDAEIER 256
+N YE L K + E++ L EQ+A + E+E+
Sbjct: 1472 ASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531
Query: 257 LHSQLSR-----TAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRI----EELTGLL 307
+ Q+ + AAL + +E + L++ +E L + DR+I EE+ L
Sbjct: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLE-LNQVKSEVDRKIAEKDEEIDQLK 1590
Query: 308 NQYRKVKEIVMVT 320
+ +V E + T
Sbjct: 1591 RNHTRVVETMQST 1603
Score = 36.2 bits (82), Expect = 0.14
Identities = 62/275 (22%), Positives = 107/275 (38%), Gaps = 33/275 (12%)
Query: 59 LALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDK 118
L E L QE + L QI I E E+ QV +E A LE +
Sbjct: 1501 LRRENKNLQQEISDLTEQI-AEGGKQIHE-LEKIKKQVEQEKCEIQAALEEAEASLEHE- 1557
Query: 119 ESLILQVSVLTDQVEAQ-----GEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQ 173
E IL++ + +QV+++ EK +++ H + + L E+ SR
Sbjct: 1558 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRV 1617
Query: 174 KLDLMTEVSELKLKL-----------------VGMEKE-QREQEEKQRKAEELLQEL--- 212
K + +++E++++L G+ KE Q ++ R E+L ++L
Sbjct: 1618 KKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIV 1677
Query: 213 ----RHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALH 268
L+ ++EEL Q E K + E+ E+V L + L + +
Sbjct: 1678 ERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDV 1737
Query: 269 SESHTERDQEIQRLKMGMETLLLANEDKDRRIEEL 303
S+ +E ++ IQ + E A D EEL
Sbjct: 1738 SQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEEL 1772
Score = 32.3 bits (72), Expect = 2.0
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 20/188 (10%)
Query: 54 IEDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLAR 113
I D + E L+ Q+ +A L ++ K+ E+++ + H + E+LA
Sbjct: 1762 ITDAAMMAEELKKEQDTSAHLERM--------KKNLEQTVKDLQHRLDEA-----EQLAL 1808
Query: 114 LEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQ 173
G K+ L+ V + E + E+ R+ E VK E +EL +T + +
Sbjct: 1809 KGGKKQIQKLEARVRELEGEVENEQKRNAEA------VKGLRKHERRVKELTYQTEEDRK 1862
Query: 174 K-LDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWK 232
L L V +L+ K+ +++ E EE+ ++L+H + EE + K
Sbjct: 1863 NVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNK 1922
Query: 233 LKATKAEV 240
L+ EV
Sbjct: 1923 LRVKSREV 1930
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 58.5 bits (140), Expect = 3e-08
Identities = 82/344 (23%), Positives = 144/344 (41%), Gaps = 56/344 (16%)
Query: 35 EPGLASPASYMNPFPVLHLIEDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLS 94
EPGL + AS + L + +L E+ L + R L Q+ E E
Sbjct: 1361 EPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQL---------EELERE-R 1410
Query: 95 QVNHHSAASNETYQERLARLEGDK----------ESLILQV--------SVLTDQVEAQG 136
Q + + Q+RLA LE ++ + ++LQ ++L Q+E +
Sbjct: 1411 QARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQ 1470
Query: 137 EKIRDLEVCLEGHQVKLNAAEEM-LQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQ 195
+ + LE LE + KL A E+ ++++++ S++ +K D E+ LK L
Sbjct: 1471 HRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSL------- 1523
Query: 196 REQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIE 255
EE+ R EL E+ L+ ++ ELE ++ +L + E +LQ + E
Sbjct: 1524 ---EEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETR 1580
Query: 256 RLHSQLSRTAA--------LHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLL 307
RL S+++ A ++S T D + L+ ++ L ++DKD I+EL L
Sbjct: 1581 RLQSEINMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRL 1640
Query: 308 --------NQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWN 343
+ ++ ++V + R LS EE G WN
Sbjct: 1641 GSVAVKREQRENHLRRSIVVIHPDTGRELS-PEEAHRAGLIDWN 1683
Score = 49.7 bits (117), Expect = 1e-05
Identities = 51/213 (23%), Positives = 102/213 (47%), Gaps = 16/213 (7%)
Query: 109 ERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRT 168
+RL DK LI + + Q++ + + ++D + ++ +V +E+LQ + +T
Sbjct: 1249 QRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEV----VQEILQFQEDPQT 1304
Query: 169 SLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQ 228
E L ++SE + K V +E+E+ QEE+ + EE EL +K +V + E R +
Sbjct: 1305 KEEVASL--RAKLSEEQKKQVDLERERASQEEQIARKEE---ELSRVKERVVQQEVVRYE 1359
Query: 229 YEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMET 288
E +AE + E + ++ +I++L ++L R TE +++++ L+ +
Sbjct: 1360 EE---PGLRAEASAFAESIDVELRQIDKLRAELRRL----QRRRTELERQLEELERERQA 1412
Query: 289 LLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQ 321
A + R + L L + + +E V TQ
Sbjct: 1413 RREAEREVQRLQQRLAALEQEEAEAREKVTHTQ 1445
Score = 47.0 bits (110), Expect = 8e-05
Identities = 65/261 (24%), Positives = 117/261 (44%), Gaps = 21/261 (8%)
Query: 109 ERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRT 168
ER +LE + +S ++ L +Q E + EV +V EE QQ L RT
Sbjct: 904 ERRRQLENEVKSTQEEIWTLRNQ--GPQESVVRKEVL---KKVPDPVLEESFQQ--LQRT 956
Query: 169 SLETQKLD--LMTEVSELKLKLVGMEKEQREQEEKQRKAEEL-LQELRHLKIKVEELENE 225
E Q + L E+ L+L+L +E+E R+ ++ E L ++ R +V +L E
Sbjct: 957 LAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREE 1016
Query: 226 RNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQ----- 280
+ A +AEV LQ++VA E R +++ + ++ + + E Q
Sbjct: 1017 LEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQED 1076
Query: 281 -----RLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQ-GPSERTLSINEEE 334
+L+ E L +DK +R+E+ + VKE++ V + +ER +S +
Sbjct: 1077 HQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQ 1136
Query: 335 PEGGFSKWNATNKDPEELFKQ 355
E +K A+ ++ EL ++
Sbjct: 1137 YEDEAAKARASQREKTELLRK 1157
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 58.2 bits (139), Expect = 3e-08
Identities = 52/228 (22%), Positives = 109/228 (47%), Gaps = 14/228 (6%)
Query: 106 TYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELL 165
T +E R++ E + L +++ + ++ DL++ ++ Q LN AEE Q
Sbjct: 853 TMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQ--- 909
Query: 166 SRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENE 225
L K+ L +V E+ +L E+ E K+RK E+ E LK +++LE
Sbjct: 910 ----LIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLED---ECSELKKDIDDLELT 962
Query: 226 RNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMG 285
+ E + AT+ +V L E++ A ++ + ++L++ E+H + ++Q +
Sbjct: 963 LAKVEKEKHATENKVKNLTEEM----AGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDK 1018
Query: 286 METLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEE 333
+ +L + ++++++L G L Q +KV+ + + E L + +E
Sbjct: 1019 VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQE 1066
Score = 56.6 bits (135), Expect = 1e-07
Identities = 46/203 (22%), Positives = 97/203 (47%), Gaps = 20/203 (9%)
Query: 109 ERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRT 168
E +A+L +K++L D ++ + +K+ L + +++ E L+QE R
Sbjct: 989 EIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRM 1048
Query: 169 SLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQ 228
LE K L ++ + ++ +E ++ + EEK +K E ++ K+E+ + Q
Sbjct: 1049 DLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKE---FDINQQNSKIEDEQVLALQ 1105
Query: 229 YEWKLKATKAEVAQLQEQVALK---DAEIERLHSQLSR--------------TAALHSES 271
+ KLK +A + +L+E++ + A++E+L S LSR ++ E
Sbjct: 1106 LQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEM 1165
Query: 272 HTERDQEIQRLKMGMETLLLANE 294
+ +R+ E Q+++ +E L +E
Sbjct: 1166 NKKREAEFQKMRRDLEEATLQHE 1188
Score = 47.4 bits (111), Expect = 6e-05
Identities = 42/194 (21%), Positives = 84/194 (43%), Gaps = 7/194 (3%)
Query: 90 EESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGH 149
EE++ VN ++ +T RL+ + E L++ V A +K R+ + L
Sbjct: 1403 EEAVEAVNAKCSSLEKTKH----RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1458
Query: 150 QVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELL 209
+ K ++ L+ SL T+ L E L +E +RE + Q + +L
Sbjct: 1459 KQKYEESQSELESSQKEARSLSTELFKLKNAYEE---SLEHLETFKRENKNLQEEISDLT 1515
Query: 210 QELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHS 269
++L V ELE R Q E + ++ + + + + ++ +I R + ++ A
Sbjct: 1516 EQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE 1575
Query: 270 ESHTERDQEIQRLK 283
E+D+E+++ K
Sbjct: 1576 RKLAEKDEEMEQAK 1589
Score = 47.4 bits (111), Expect = 6e-05
Identities = 77/330 (23%), Positives = 141/330 (42%), Gaps = 64/330 (19%)
Query: 54 IEDLRLALEMLELPQERAALLSQIPGPTAAYIKEW---FEESLSQV--NHHSAASNET-- 106
IEDL + +E AA L + + EW +EES S++ + A S T
Sbjct: 1427 IEDLMVDVER---SNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 107 ------YQERLARLEGDK---ESLILQVSVLTDQVEAQGEKIRDLEVC---LEGHQVKLN 154
Y+E L LE K ++L ++S LT+Q+ G+ + +LE LE +++L
Sbjct: 1484 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ 1543
Query: 155 AAEEMLQQEL------LSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEEL 208
+A E + L + R LE ++ +E++ KL ++E + + ++ +
Sbjct: 1544 SALEEAEASLEHEEGKILRAQLEFNQIK-----AEIERKLAEKDEEMEQAKRNHQRVVDS 1598
Query: 209 LQ-----ELRH----LKIKVEELENERNQYEWKLKATKAEVAQLQEQV-----ALKDAEI 254
LQ E R L++K +++E + N+ E +L A+ Q+QV LKD +I
Sbjct: 1599 LQTSLDAETRSRNEVLRVK-KKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQI 1657
Query: 255 E-----RLHSQLSRTAALHSESHTERDQEIQRL-----------KMGMETLLLANEDKDR 298
+ R + L A+ + E++ L K+ + L+ +E
Sbjct: 1658 QLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 1717
Query: 299 RIEELTGLLNQYRKVKEIVMVTQGPSERTL 328
+ T L+NQ +K++ + Q E +
Sbjct: 1718 LHSQNTSLINQKKKMESDLTQLQSEVEEAV 1747
Score = 46.2 bits (108), Expect = 1e-04
Identities = 56/245 (22%), Positives = 107/245 (43%), Gaps = 25/245 (10%)
Query: 81 TAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVE------A 134
TAA +++ +S++++ + Q +LE +K L++ +T +E A
Sbjct: 1190 TAAALRKKHADSVAELGEQI----DNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 1245
Query: 135 QGEKI-RDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEK 193
EK+ R LE ++VKL A+ L TQ+ L TE EL +L E+
Sbjct: 1246 NLEKVSRTLEDQANEYRVKLEEAQRSL-------NDFTTQRAKLQTENGELARQL---EE 1295
Query: 194 EQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALK--- 250
++ + R Q++ LK ++EE +N L++ + + L+EQ +
Sbjct: 1296 KEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEA 1355
Query: 251 DAEIERLHSQL-SRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQ 309
AE++R+ S+ S A ++ T+ Q + L+ + L +D + +E + +
Sbjct: 1356 KAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSS 1415
Query: 310 YRKVK 314
K K
Sbjct: 1416 LEKTK 1420
Score = 43.9 bits (102), Expect = 7e-04
Identities = 53/206 (25%), Positives = 95/206 (46%), Gaps = 21/206 (10%)
Query: 103 SNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQ 162
+N+ +E +A +E L ++ L VE Q E+ R L + +L E +Q
Sbjct: 1665 ANDDLKENIAIVERRNNLLQAELEELRAVVE-QTERSRKLA------EQELIETSERVQL 1717
Query: 163 ELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRK----AEELLQELRHLKIK 218
TSL QK + +++++L+ ++ +E R EEK +K A + +EL+ +
Sbjct: 1718 LHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDT 1777
Query: 219 VEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQE 278
LE + E +K + + + EQ+ALK + ++L +R L E E+ +
Sbjct: 1778 SAHLERMKKNMEQTIKDLQHRLDE-AEQIALKGGK-KQLQKLEARVRELEGELEAEQKRN 1835
Query: 279 IQRLKMGMETLLLANEDKDRRIEELT 304
+ +K GM +RRI+ELT
Sbjct: 1836 AESVK-GM-------RKSERRIKELT 1853
Score = 37.4 bits (85), Expect = 0.061
Identities = 64/304 (21%), Positives = 122/304 (40%), Gaps = 34/304 (11%)
Query: 62 EMLELPQERAALLSQIPGPTAAY------IKEWFEE----------SLSQVNHHSAASNE 105
E+ +E+ AL+SQ+ +Y +K EE +L H E
Sbjct: 1288 ELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLRE 1347
Query: 106 TYQERL---ARLEGDKESLILQVSVLTDQVEAQG-EKIRDLEVCLEGHQVKLNAAEEMLQ 161
Y+E A L+ +V+ + E ++ +LE + +L AEE ++
Sbjct: 1348 QYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVE 1407
Query: 162 QELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEE 221
+SLE K L E+ +L + + ++KQR +++L E + K + +
Sbjct: 1408 AVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ-KYEESQ 1466
Query: 222 LENERNQYE--------WKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHT 273
E E +Q E +KLK E + E ++ ++ S L+ ++
Sbjct: 1467 SELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVH 1526
Query: 274 ERDQEIQRLKMGMETLLLANEDKDRRIEELTG-LLNQYRKVKEIVMVTQGPSERTLSINE 332
E ++ ++L++ L A E+ + +E G +L + +I + ER L+ +
Sbjct: 1527 ELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQI----KAEIERKLAEKD 1582
Query: 333 EEPE 336
EE E
Sbjct: 1583 EEME 1586
Score = 35.0 bits (79), Expect = 0.30
Identities = 43/183 (23%), Positives = 83/183 (45%), Gaps = 18/183 (9%)
Query: 108 QERLARLEGDKESLILQVSVLTDQVEAQGEKIR-DLEVCLEGHQVKLNAAEEMLQQELLS 166
+E RLE + +Q+ + + EA+ +K+R DLE H+ A + +
Sbjct: 1146 EEISERLEEAGGATSVQIE-MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE 1204
Query: 167 R----TSLETQKLDLMTEVSELKLKL----VGMEKEQREQEEKQRKAEELLQELRHLKIK 218
+L+ K L E SE KL+L ME+ + + ++ + L + ++K
Sbjct: 1205 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVK 1264
Query: 219 VEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQE 278
+EE + N + + + E +L Q+ K+A L SQL+R S+T++ ++
Sbjct: 1265 LEEAQRSLNDFTTQRAKLQTENGELARQLEEKEA----LISQLTRGKL----SYTQQMED 1316
Query: 279 IQR 281
++R
Sbjct: 1317 LKR 1319
Score = 34.3 bits (77), Expect = 0.52
Identities = 44/201 (21%), Positives = 90/201 (44%), Gaps = 23/201 (11%)
Query: 54 IEDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLAR 113
I D + E L+ Q+ +A L ++ K+ E+++ + H + E++A
Sbjct: 1761 ITDAAMMAEELKKEQDTSAHLERM--------KKNMEQTIKDLQHRLDEA-----EQIAL 1807
Query: 114 LEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQ 173
G K+ L+ V + E + E+ R+ E VK E +EL +T + +
Sbjct: 1808 KGGKKQLQKLEARVRELEGELEAEQKRNAE------SVKGMRKSERRIKELTYQTEEDKK 1861
Query: 174 KL-DLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWK 232
L L V +L+LK ++ +R+ EE + +A L + R ++ +++E E + E +
Sbjct: 1862 NLLRLQDLVDKLQLK---VKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1918
Query: 233 LKATKAEVAQLQEQVALKDAE 253
+ +A+ + + + D E
Sbjct: 1919 VNKLRAKSRDIGAKQKMHDEE 1939
Score = 33.9 bits (76), Expect = 0.68
Identities = 29/126 (23%), Positives = 63/126 (50%), Gaps = 10/126 (7%)
Query: 140 RDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQE 199
+++E ++ Q +L+ AE++ L + QKL+ V EL+ +L +K E
Sbjct: 1786 KNMEQTIKDLQHRLDEAEQIA----LKGGKKQLQKLE--ARVRELEGELEAEQKRNAESV 1839
Query: 200 EKQRKAEELLQELRHL----KIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIE 255
+ RK+E ++EL + K + L++ ++ + K+KA K + + +EQ ++
Sbjct: 1840 KGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFR 1899
Query: 256 RLHSQL 261
++ +L
Sbjct: 1900 KVQHEL 1905
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 58.2 bits (139), Expect = 3e-08
Identities = 84/361 (23%), Positives = 158/361 (43%), Gaps = 51/361 (14%)
Query: 20 IAGTKTGADLSDGTCEPGLASPASYMNPFPVLHL-IEDLRLALEMLELPQERAALLSQIP 78
IA K + S+ TC + + + LHL I+D+ A LE E+ + L +
Sbjct: 1685 IAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALE---EQLSRLQREK 1741
Query: 79 GPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEK 138
++E E+ + H AA + ++ + Q++ L Q+E ++
Sbjct: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRD------------LAQINDLQAQLEEANKE 1789
Query: 139 IRDLEVCLEGHQVKLNAAEE-MLQQELLSRTSLETQKLDLMTEVSELKLK-LVGMEKEQR 196
++L+ L+ Q ++ E+ M+ + L+SR + ++L+ E ++K L + +
Sbjct: 1790 KQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLK 1849
Query: 197 EQEEKQRKAEELLQELRHLKIKVEELENERNQ-YEWKLKATKAEVAQLQEQVALKDAEIE 255
E EK L E R +I E E E+N+ + +L+ TK E+ +L A K+AE
Sbjct: 1850 ENMEK-------LTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGEL----ARKEAEAS 1898
Query: 256 RLHSQLSRTAALHSESHTERDQEIQR-----------LKMGMETLLLANEDKDRRIEELT 304
R +L + ES +Q +Q L+ +E + ++E++D I L
Sbjct: 1899 RKKHELE----MDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENED-LINSLQ 1953
Query: 305 GLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSP 364
++ +Y+K K + +G S+ + E+ G W + NK P + + + SSP
Sbjct: 1954 DMVTKYQKRKNKL---EGDSD--VDSELEDRVDGVKSWLSKNKGPSKAASDDGSLKSSSP 2008
Query: 365 T 365
T
Sbjct: 2009 T 2009
Score = 55.8 bits (133), Expect = 2e-07
Identities = 57/240 (23%), Positives = 103/240 (42%), Gaps = 47/240 (19%)
Query: 108 QERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVK--------------L 153
+ RL L+ D E + L + + +++D ++ LEG QV+ L
Sbjct: 1408 ERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSEL 1467
Query: 154 NAAEEMLQQELLSRTSLETQKLDLMTEVSELK--------------LKLVGMEKEQREQE 199
+ A E Q+E L R L+ +K L+ E LK K+V +E E ++
Sbjct: 1468 SQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDIS 1527
Query: 200 EKQRKAEELL----QELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIE 255
++ K E L ++LR L+ KV++ E E ++ +A Q+ EQ L
Sbjct: 1528 SQESKDEASLAKVKKQLRDLEAKVKDQEEELDE--------QAGTIQMLEQAKL------ 1573
Query: 256 RLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANE-DKDRRIEELTGLLNQYRKVK 314
RL ++ R HS+ RD+E++ + + L E + E+ +L + R+++
Sbjct: 1574 RLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633
Score = 51.2 bits (121), Expect = 4e-06
Identities = 70/318 (22%), Positives = 139/318 (43%), Gaps = 46/318 (14%)
Query: 55 EDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARL 114
E R L+ +L +E+ LL++ A +K+ EE + + +++ L
Sbjct: 1473 EAQREKLQREKLQREKDMLLAE-----AFSLKQQLEEKDMDI--------AGFTQKVVSL 1519
Query: 115 EGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQK 174
E + + + Q S + +++RDLE K+ EE L ++ + LE K
Sbjct: 1520 EAELQDISSQESKDEASLAKVKKQLRDLEA-------KVKDQEEELDEQAGTIQMLEQAK 1572
Query: 175 LDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLK 234
L L E+ ++ + E E R++E ++ + + ++L+ +++++EE ++ + + +
Sbjct: 1573 LRLEMEMERMR-QTHSKEMESRDEEVEEAR-QSCQKKLKQMEVQLEEEYEDKQKVLREKR 1630
Query: 235 ATKAEVAQLQEQVALKDAEIE-RLHSQLSRTAAL---------HSESHTERDQEIQRLKM 284
+ ++A L +QV +D E E RL L RT AL H ++ +EI +LK
Sbjct: 1631 ELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKN 1690
Query: 285 GME-------TLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEG 337
+E + A + + IE+L ++ K K + E LS + E
Sbjct: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL-------EEQLSRLQREKNE 1743
Query: 338 GFSKWNATNKDPEELFKQ 355
++ +D EL K+
Sbjct: 1744 IQNRLEEDQEDMNELMKK 1761
Score = 38.5 bits (88), Expect = 0.028
Identities = 52/231 (22%), Positives = 91/231 (39%), Gaps = 12/231 (5%)
Query: 54 IEDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLAR 113
I+ LR LE E + L S + I E E + N +AS E R
Sbjct: 1263 IQQLRSKLEKAEKERNELRLNSD---RLESRISELTSELTDERNTGESASQLLDAETAER 1319
Query: 114 LEGDKE--SLILQVSVLTDQVEAQGEKIRDLEVC----LEGHQVKLNAAEEMLQQELLSR 167
L +KE L Q L Q+E ++ + + + G +A E + +
Sbjct: 1320 LRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAV 1379
Query: 168 TSLETQKLDLMTEVSELKLKLVGMEKEQREQE--EKQRKAEELLQELRHLKIKVEELENE 225
++ K L E + KL++ K Q E+ + Q +EE + L+ LK K + L E
Sbjct: 1380 REVDFTKKRLQQEFED-KLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAE 1438
Query: 226 RNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERD 276
+ L+ + +L+++ D+E+ + H + R + E+D
Sbjct: 1439 LQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKD 1489
Score = 33.9 bits (76), Expect = 0.68
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 23/121 (19%)
Query: 198 QEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQ---EQVALKDAEI 254
Q K+RK ++L +R ++ +++ + ++ WKL T + ++Q EQ+ KD EI
Sbjct: 1206 QHFKKRKIQDLA--IRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEI 1263
Query: 255 ERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVK 314
++L S+L + ++E L++ + L + RI ELT L R
Sbjct: 1264 QQLRSKLEKA-----------EKERNELRLNSDRL-------ESRISELTSELTDERNTG 1305
Query: 315 E 315
E
Sbjct: 1306 E 1306
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,721,839
Number of Sequences: 37866
Number of extensions: 1786018
Number of successful extensions: 14456
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 379
Number of HSP's successfully gapped in prelim test: 900
Number of HSP's that attempted gapping in prelim test: 7605
Number of HSP's gapped (non-prelim): 4273
length of query: 876
length of database: 18,247,518
effective HSP length: 111
effective length of query: 765
effective length of database: 14,044,392
effective search space: 10743959880
effective search space used: 10743959880
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.