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Search of human proteins with 170763517
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170763517 transforming, acidic coiled-coil containing
protein 1 isoform 1 [Homo sapiens]
(805 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170763517 transforming, acidic coiled-coil containing protein... 1592 0.0
gi|226246618 transforming, acidic coiled-coil containing protein... 1200 0.0
gi|170763519 transforming, acidic coiled-coil containing protein... 664 0.0
gi|45827753 transforming, acidic coiled-coil containing protein ... 313 5e-85
gi|150418009 transforming, acidic coiled-coil containing protein... 306 4e-83
gi|45827755 transforming, acidic coiled-coil containing protein ... 306 4e-83
gi|11119414 transforming, acidic coiled-coil containing protein ... 306 4e-83
gi|5454102 transforming, acidic coiled-coil containing protein 3... 240 4e-63
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 56 1e-07
gi|156104908 myosin heavy chain 6 [Homo sapiens] 55 2e-07
gi|71061468 centromere protein E [Homo sapiens] 55 3e-07
gi|31982906 cingulin-like 1 [Homo sapiens] 55 3e-07
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 54 4e-07
gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo sa... 54 4e-07
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 53 1e-06
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 53 1e-06
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 53 1e-06
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 53 1e-06
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 53 1e-06
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 53 1e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 52 3e-06
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 51 4e-06
gi|56550043 sarcolemma associated protein [Homo sapiens] 51 4e-06
gi|58530840 desmoplakin isoform I [Homo sapiens] 51 5e-06
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 50 8e-06
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 50 8e-06
gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi... 50 8e-06
gi|225579095 S-phase cyclin A-associated protein in the ER isofo... 50 1e-05
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 50 1e-05
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 50 1e-05
>gi|170763517 transforming, acidic coiled-coil containing protein 1
isoform 1 [Homo sapiens]
Length = 805
Score = 1592 bits (4121), Expect = 0.0
Identities = 805/805 (100%), Positives = 805/805 (100%)
Query: 1 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN 60
MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN
Sbjct: 1 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGN 60
Query: 61 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN 120
FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN
Sbjct: 61 FETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSEN 120
Query: 121 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG 180
EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG
Sbjct: 121 EVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSG 180
Query: 181 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK 240
KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK
Sbjct: 181 KALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRK 240
Query: 241 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS 300
KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS
Sbjct: 241 KAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSS 300
Query: 301 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK 360
DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK
Sbjct: 301 DTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK 360
Query: 361 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD 420
SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD
Sbjct: 361 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD 420
Query: 421 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVKKHETQSLALD 480
NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVKKHETQSLALD
Sbjct: 421 NFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVKKHETQSLALD 480
Query: 481 ACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVP 540
ACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVP
Sbjct: 481 ACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVP 540
Query: 541 VSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSE 600
VSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSE
Sbjct: 541 VSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSE 600
Query: 601 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTS 660
SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTS
Sbjct: 601 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTS 660
Query: 661 MTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYL 720
MTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYL
Sbjct: 661 MTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYL 720
Query: 721 ARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERAL 780
ARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERAL
Sbjct: 721 ARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERAL 780
Query: 781 QQKNQEIEELTKICDELIAKLGKTD 805
QQKNQEIEELTKICDELIAKLGKTD
Sbjct: 781 QQKNQEIEELTKICDELIAKLGKTD 805
>gi|226246618 transforming, acidic coiled-coil containing protein 1
isoform 3 [Homo sapiens]
Length = 610
Score = 1200 bits (3104), Expect = 0.0
Identities = 610/610 (100%), Positives = 610/610 (100%)
Query: 196 MTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFSDTNAAVE 255
MTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFSDTNAAVE
Sbjct: 1 MTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFSDTNAAVE 60
Query: 256 GTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVELGEESRS 315
GTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVELGEESRS
Sbjct: 61 GTPLPKASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVELGEESRS 120
Query: 316 SPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPVARDG 375
SPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPVARDG
Sbjct: 121 SPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPVARDG 180
Query: 376 PLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPTTTL 435
PLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPTTTL
Sbjct: 181 PLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPTTTL 240
Query: 436 TSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVKKHETQSLALDACSRDEGAVISQISD 495
TSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVKKHETQSLALDACSRDEGAVISQISD
Sbjct: 241 TSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVKKHETQSLALDACSRDEGAVISQISD 300
Query: 496 ISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGI 555
ISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGI
Sbjct: 301 ISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGI 360
Query: 556 EKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEII 615
EKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEII
Sbjct: 361 EKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEII 420
Query: 616 TKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKE 675
TKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKE
Sbjct: 421 TKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKE 480
Query: 676 QALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKI 735
QALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKI
Sbjct: 481 QALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKI 540
Query: 736 HAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICD 795
HAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICD
Sbjct: 541 HAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICD 600
Query: 796 ELIAKLGKTD 805
ELIAKLGKTD
Sbjct: 601 ELIAKLGKTD 610
>gi|170763519 transforming, acidic coiled-coil containing protein 1
isoform 2 [Homo sapiens]
Length = 395
Score = 664 bits (1713), Expect = 0.0
Identities = 347/363 (95%), Positives = 350/363 (96%), Gaps = 2/363 (0%)
Query: 443 PTGNHVNEILESPKKAKSRLITSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGH 502
P G+ E +S + KS SGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGH
Sbjct: 35 PEGDPEEE--DSQAETKSLSFRSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGH 92
Query: 503 ATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQK 562
ATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQK
Sbjct: 93 ATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQK 152
Query: 563 MEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEAN 622
MEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEAN
Sbjct: 153 MEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEAN 212
Query: 623 EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLN 682
EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLN
Sbjct: 213 EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLN 272
Query: 683 SVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLD 742
SVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLD
Sbjct: 273 SVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLD 332
Query: 743 KANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLG 802
KANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLG
Sbjct: 333 KANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLG 392
Query: 803 KTD 805
KTD
Sbjct: 393 KTD 395
Score = 117 bits (293), Expect = 4e-26
Identities = 54/55 (98%), Positives = 54/55 (98%)
Query: 1 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFSS 55
MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSF S
Sbjct: 1 MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEEEDSQAETKSLSFRS 55
>gi|45827753 transforming, acidic coiled-coil containing protein 2
isoform c [Homo sapiens]
Length = 996
Score = 313 bits (801), Expect = 5e-85
Identities = 274/858 (31%), Positives = 398/858 (46%), Gaps = 110/858 (12%)
Query: 27 AGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAG 86
A + + G+PE + S SS S T + P + + P+
Sbjct: 169 ASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPT---ET 225
Query: 87 PGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKI 146
P K + QE DE+ + E +S+T ++ ++ E P A+ E P
Sbjct: 226 PPVKETQ-QEPDEESLVPSGENLASETKTESAKTEGPSPAL-------LEETPLEPAVGP 277
Query: 147 SIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSS---------PPDALQDEAMT 197
P E+ + A G + + V K LP + P D+ E
Sbjct: 278 KAACPLDSESAEGVVPPASGGGRVQNS--PPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP 335
Query: 198 EGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKP-KPVPLRK---KAIGGEFSDTNAA 253
+ V LE D + ++ E P + +KP +PLR+ K + +T A+
Sbjct: 336 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS 395
Query: 254 VEGTP-------LPKASYHFSPEELDE-NTSPLLGDARFQKSPPDLKETPGTLSSDTNDS 305
+P + K +Y F ++ D+ N +P ++ Q+SP L + DT D
Sbjct: 396 PPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQSYNFDPDTCDE 454
Query: 306 GVE---LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTP-KIQKDGISKS 361
V+ ++ SSP K F +EA L + TP K + KS
Sbjct: 455 SVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKS 514
Query: 362 AGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDN 421
+DP ++D + T E+P H+ + ++++ D
Sbjct: 515 PKRSPLSDPPSQDPTPAATP--------ETPPVISAVVHATDEEKLAVTNQKWTCMTVDL 566
Query: 422 FDESMDPFKPT---TTLTSSDFCSPT-----------------GNHVNEILESPKKAKSR 461
+ D +P+ T + + F SPT G+ + + ++PKK
Sbjct: 567 EADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALY 626
Query: 462 LI-------------------TSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGH 502
L+ + C E ++ ++++ V ++ N++ H
Sbjct: 627 LMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAP--NQESH 684
Query: 503 ATDEEKLASTSCGQKSAGAEVKGEPEEDLEY------FECSNVPVSTINHAFSSSEAGIE 556
EK + QK A G P E +E F ++ +S + H S A
Sbjct: 685 LQVPEKSS-----QKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDY 739
Query: 557 KETCQKMEEDGSTVLGLLESSAEKAPVSVSCGG----------ESPLDGICLSESDKTAV 606
E + L +A VS+S E P G+ + D +
Sbjct: 740 LEPDLAEKNPPLFAQKLQREAAHPTDVSISKTALYSRIGTAEVEKPA-GLLFQQPDLDSA 798
Query: 607 LTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKS 666
L + R EIITKE E +EWK KYEE+R+EV+EMRKIVAEYEKTIAQMIEDEQR S ++
Sbjct: 799 LQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQT 858
Query: 667 FQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQE 726
QQL +EKEQALADLNSVE+SL+DLFRRYE +K VLEGF+KNEE LK+CAQ+YL+RVK+E
Sbjct: 859 VQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKE 918
Query: 727 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQE 786
EQRYQALK+HAEEKLD+AN EIAQVR KA+ E AA A LRKEQ++V++LER L+QKN+E
Sbjct: 919 EQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKE 978
Query: 787 IEELTKICDELIAKLGKT 804
IEELTKICDELIAK+GK+
Sbjct: 979 IEELTKICDELIAKMGKS 996
Score = 122 bits (306), Expect = 1e-27
Identities = 166/639 (25%), Positives = 261/639 (40%), Gaps = 120/639 (18%)
Query: 50 SLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKC 109
S + SSDSE FETPE+ TP+++P P + P +Q E C
Sbjct: 20 SEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEE---------PGC 70
Query: 110 SSKTCSKP-----SENEVPQQAIDSHSVKNFREEPEH---------DFSKISIVRPFSI- 154
S+T P E SHS +E + DF I +V F
Sbjct: 71 GSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTL 130
Query: 155 --ETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEAD 212
D+ + + T+ +S L S +LQ S EA A A
Sbjct: 131 EPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSL--SLQASDFDGASSSGNPEAVALAP 188
Query: 213 LKAGNSCPELVPSRRSKLRKPKPVPLRKKA-----------------------------I 243
A ++ S + +KP+P L+KK +
Sbjct: 189 -DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENL 247
Query: 244 GGEFSDTNAAVEG--------TPL-----PKASYHFSPEELDENTSPLLGDARFQKSPPD 290
E +A EG TPL PKA+ E + P G R Q SPP
Sbjct: 248 ASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPV 307
Query: 291 LKET-PGTLSSDT-----NDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALP---RKL 341
++T P T + + +DSG + ++ ++LEFD++ED + + ++ P +K+
Sbjct: 308 GRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 367
Query: 342 GRKLGSTL---TPKIQKD----GISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSF 394
G+K + + PK++K + ++ P +P D P+++ + D +W+ P+F
Sbjct: 368 GKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEP--NDIPIAKGTYTFDIDKWDDPNF 425
Query: 395 NPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHV------ 448
NPF S S +Q SP L + SY+FDPD DES+DPFK ++ SS SP +
Sbjct: 426 NPFSSTSKMQESPKLPQQ-SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAME 484
Query: 449 -----NEILESP-KKAKSRLITSGCKVKKHETQSLALDACSRD-EGAVISQISDISNRDG 501
+ L P KK K+ L T +VKK +S D S+D A + + +
Sbjct: 485 ANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVV 544
Query: 502 HATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET-- 559
HATDEEKLA T+ QK V E ++ +Y + S++ FSS ++
Sbjct: 545 HATDEEKLAVTN--QKWTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRNSY 601
Query: 560 -CQKMEEDGSTV-----------LGLLESSAEKAPVSVS 586
+ ME+ GS++ L L+ +++++PV S
Sbjct: 602 EIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSS 640
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 306 bits (785), Expect = 4e-83
Identities = 279/891 (31%), Positives = 410/891 (46%), Gaps = 146/891 (16%)
Query: 27 AGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAG 86
A + + G+PE + S SS S T + P + + P+
Sbjct: 2091 ASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPT---ET 2147
Query: 87 PGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKI 146
P K + QE DE+ + E +S+T ++ ++ E P A+ E P
Sbjct: 2148 PPVKETQ-QEPDEESLVPSGENLASETKTESAKTEGPSPAL-------LEETPLEPAVGP 2199
Query: 147 SIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSS---------PPDALQDEAMT 197
P E+ + A G + + V K LP + P D+ E
Sbjct: 2200 KAACPLDSESAEGVVPPASGGGRVQNS--PPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP 2257
Query: 198 EGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKP-KPVPLRK---KAIGGEFSDTNAA 253
+ V LE D + ++ E P + +KP +PLR+ K + +T A+
Sbjct: 2258 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS 2317
Query: 254 VEGTP-------LPKASYHFSPEELDE-NTSPLLGDARFQKSPPDLKETPGTLSSDTNDS 305
+P + K +Y F ++ D+ N +P ++ Q+SP L + DT D
Sbjct: 2318 PPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQSYNFDPDTCDE 2376
Query: 306 GVE---LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTP-KIQKDGISKS 361
V+ ++ SSP K F +EA L + TP K + KS
Sbjct: 2377 SVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKS 2436
Query: 362 AGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGS---HSVLQNSPPLSSEGSYHFD 418
+ PLS S+ DP+ +P P S H+ + ++++
Sbjct: 2437 P----------KRSPLSDPPSQ-DPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 2485
Query: 419 PDNFDESMDPFKPT---TTLTSSDFCSPT-----------------GNHVNEILESPKKA 458
D + D +P+ T + + F SPT G+ + + ++PKK
Sbjct: 2486 VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 2545
Query: 459 KSRLI-------------------TSGCKVKKHETQSLALDACSRDEGAVISQISDISNR 499
L+ + C E ++ ++++ V ++ N+
Sbjct: 2546 ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAP--NQ 2603
Query: 500 DGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEY------FECSNVPVSTINH------A 547
+ H EK + QK A G P E +E F ++ +S + H A
Sbjct: 2604 ESHLQVPEKSS-----QKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGA 2658
Query: 548 FSSSEAGIEKET----CQKMEEDGSTVLGLLES--------------------SAEKAPV 583
E + ++ QK++E+ + +E+ +A V
Sbjct: 2659 LDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDV 2718
Query: 584 SVSCGG----------ESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQ 633
S+S E P G+ + D + L + R EIITKE E +EWK KYEE+R+
Sbjct: 2719 SISKTALYSRIGTAEVEKPA-GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR 2777
Query: 634 EVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFR 693
EV+EMRKIVAEYEKTIAQMIEDEQR S ++ QQL +EKEQALADLNSVE+SL+DLFR
Sbjct: 2778 EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR 2837
Query: 694 RYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRT 753
RYE +K VLEGF+KNEE LK+CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR
Sbjct: 2838 RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG 2897
Query: 754 KAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKT 804
KA+ E AA A LRKEQ++V++LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 2898 KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 2948
Score = 127 bits (318), Expect = 5e-29
Identities = 172/657 (26%), Positives = 268/657 (40%), Gaps = 123/657 (18%)
Query: 35 PEGDPEEEDSQA---ETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKS 91
P GD E + + K LS SSDSE FETPE+ TP+++P P + P +
Sbjct: 1924 PAGDRVEASTPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST 1983
Query: 92 QESQEADEQLVAEVVEKCSSKTCSKP-----SENEVPQQAIDSHSVKNFREEPEH----- 141
Q E C S+T P E SHS +E +
Sbjct: 1984 QPPPEE---------PGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSG 2034
Query: 142 ----DFSKISIVRPFSI---ETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDE 194
DF I +V F D+ + + T+ +S L S +LQ
Sbjct: 2035 TYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSL--SLQAS 2092
Query: 195 AMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKA------------ 242
S EA A A A ++ S + +KP+P L+KK
Sbjct: 2093 DFDGASSSGNPEAVALAP-DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVK 2151
Query: 243 -----------------IGGEFSDTNAAVEG--------TPL-----PKASYHFSPEELD 272
+ E +A EG TPL PKA+ E +
Sbjct: 2152 ETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAE 2211
Query: 273 ENTSPLLGDARFQKSPPDLKET-PGTLSSDT-----NDSGVELGEESRSSPLKLEFDFTE 326
P G R Q SPP ++T P T + + +DSG + ++ ++LEFD++E
Sbjct: 2212 GVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSE 2271
Query: 327 DTGNIEARKALP---RKLGRKLGSTL---TPKIQKD----GISKSAGLEQPTDPVARDGP 376
D + + ++ P +K+G+K + + PK++K + ++ P +P D P
Sbjct: 2272 DKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEP--NDIP 2329
Query: 377 LSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPTTTLT 436
+++ + D +W+ P+FNPF S S +Q SP L + SY+FDPD DES+DPFK ++
Sbjct: 2330 IAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ-SYNFDPDTCDESVDPFKTSSKTP 2388
Query: 437 SSDFCSPTGNHV-----------NEILESP-KKAKSRLITSGCKVKKHETQSLALDACSR 484
SS SP + + L P KK K+ L T +VKK +S D S+
Sbjct: 2389 SSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQ 2448
Query: 485 D-EGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVST 543
D A + + + HATDEEKLA T+ QK V E ++ +Y + S++
Sbjct: 2449 DPTPAATPETPPVISAVVHATDEEKLAVTN--QKWTCMTVDLEADKQ-DYPQPSDLSTFV 2505
Query: 544 INHAFSSSEAGIEKET---CQKMEEDGSTV-----------LGLLESSAEKAPVSVS 586
FSS ++ + ME+ GS++ L L+ +++++PV S
Sbjct: 2506 NETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSS 2562
Score = 37.0 bits (84), Expect = 0.073
Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 22/190 (11%)
Query: 252 AAVEGTPLPKASYH------FSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDS 305
A +E L +SYH S + + ++ SP A S + +P + D ++
Sbjct: 1872 ADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAHAGLPPSAAEHIVSPSAPAGDRVEA 1931
Query: 306 GVELGEE-----SRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISK 360
+ SRSS + F+ E T ++A A P + P++ +
Sbjct: 1932 STPSCPDPAKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPE---PEVSTQPPPE 1988
Query: 361 SAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPD 420
G T PV DGP S S + P + S SF+ +V P++S G+Y+ D D
Sbjct: 1989 EPGCGSETVPVP-DGPRSD-SVEGSPFRPPSHSFS-----AVFDEDKPIASSGTYNLDFD 2041
Query: 421 NFDESMDPFK 430
N E +D F+
Sbjct: 2042 NI-ELVDTFQ 2050
>gi|45827755 transforming, acidic coiled-coil containing protein 2
isoform b [Homo sapiens]
Length = 1094
Score = 306 bits (785), Expect = 4e-83
Identities = 279/891 (31%), Positives = 410/891 (46%), Gaps = 146/891 (16%)
Query: 27 AGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAG 86
A + + G+PE + S SS S T + P + + P+
Sbjct: 237 ASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPT---ET 293
Query: 87 PGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKI 146
P K + QE DE+ + E +S+T ++ ++ E P A+ E P
Sbjct: 294 PPVKETQ-QEPDEESLVPSGENLASETKTESAKTEGPSPAL-------LEETPLEPAVGP 345
Query: 147 SIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSS---------PPDALQDEAMT 197
P E+ + A G + + V K LP + P D+ E
Sbjct: 346 KAACPLDSESAEGVVPPASGGGRVQNS--PPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP 403
Query: 198 EGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKP-KPVPLRK---KAIGGEFSDTNAA 253
+ V LE D + ++ E P + +KP +PLR+ K + +T A+
Sbjct: 404 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS 463
Query: 254 VEGTP-------LPKASYHFSPEELDE-NTSPLLGDARFQKSPPDLKETPGTLSSDTNDS 305
+P + K +Y F ++ D+ N +P ++ Q+SP L + DT D
Sbjct: 464 PPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQSYNFDPDTCDE 522
Query: 306 GVE---LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTP-KIQKDGISKS 361
V+ ++ SSP K F +EA L + TP K + KS
Sbjct: 523 SVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKS 582
Query: 362 AGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGS---HSVLQNSPPLSSEGSYHFD 418
+ PLS S+ DP+ +P P S H+ + ++++
Sbjct: 583 P----------KRSPLSDPPSQ-DPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 631
Query: 419 PDNFDESMDPFKPT---TTLTSSDFCSPT-----------------GNHVNEILESPKKA 458
D + D +P+ T + + F SPT G+ + + ++PKK
Sbjct: 632 VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 691
Query: 459 KSRLI-------------------TSGCKVKKHETQSLALDACSRDEGAVISQISDISNR 499
L+ + C E ++ ++++ V ++ N+
Sbjct: 692 ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAP--NQ 749
Query: 500 DGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEY------FECSNVPVSTINH------A 547
+ H EK + QK A G P E +E F ++ +S + H A
Sbjct: 750 ESHLQVPEKSS-----QKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGA 804
Query: 548 FSSSEAGIEKET----CQKMEEDGSTVLGLLES--------------------SAEKAPV 583
E + ++ QK++E+ + +E+ +A V
Sbjct: 805 LDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDV 864
Query: 584 SVSCGG----------ESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQ 633
S+S E P G+ + D + L + R EIITKE E +EWK KYEE+R+
Sbjct: 865 SISKTALYSRIGTAEVEKPA-GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR 923
Query: 634 EVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFR 693
EV+EMRKIVAEYEKTIAQMIEDEQR S ++ QQL +EKEQALADLNSVE+SL+DLFR
Sbjct: 924 EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR 983
Query: 694 RYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRT 753
RYE +K VLEGF+KNEE LK+CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR
Sbjct: 984 RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG 1043
Query: 754 KAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKT 804
KA+ E AA A LRKEQ++V++LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 1044 KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1094
Score = 121 bits (304), Expect = 2e-27
Identities = 165/635 (25%), Positives = 259/635 (40%), Gaps = 120/635 (18%)
Query: 54 SSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKT 113
SSDSE FETPE+ TP+++P P + P +Q E C S+T
Sbjct: 92 SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEE---------PGCGSET 142
Query: 114 CSKP-----SENEVPQQAIDSHSVKNFREEPEH---------DFSKISIVRPFSI---ET 156
P E SHS +E + DF I +V F
Sbjct: 143 VPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRA 202
Query: 157 KDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAG 216
D+ + + T+ +S L S +LQ S EA A A A
Sbjct: 203 SDAKNQEGKVNTRRKSTDSVPISKSTLSRSL--SLQASDFDGASSSGNPEAVALAP-DAY 259
Query: 217 NSCPELVPSRRSKLRKPKPVPLRKKA-----------------------------IGGEF 247
++ S + +KP+P L+KK + E
Sbjct: 260 STGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASET 319
Query: 248 SDTNAAVEG--------TPL-----PKASYHFSPEELDENTSPLLGDARFQKSPPDLKET 294
+A EG TPL PKA+ E + P G R Q SPP ++T
Sbjct: 320 KTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKT 379
Query: 295 -PGTLSSDT-----NDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALP---RKLGRKL 345
P T + + +DSG + ++ ++LEFD++ED + + ++ P +K+G+K
Sbjct: 380 LPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 439
Query: 346 GSTL---TPKIQKD----GISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFG 398
+ + PK++K + ++ P +P D P+++ + D +W+ P+FNPF
Sbjct: 440 VAKMPLRRPKMKKTPEKLDNTPASPPRSPAEP--NDIPIAKGTYTFDIDKWDDPNFNPFS 497
Query: 399 SHSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHV---------- 448
S S +Q SP L + SY+FDPD DES+DPFK ++ SS SP +
Sbjct: 498 STSKMQESPKLPQQ-SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGV 556
Query: 449 -NEILESP-KKAKSRLITSGCKVKKHETQSLALDACSRD-EGAVISQISDISNRDGHATD 505
+ L P KK K+ L T +VKK +S D S+D A + + + HATD
Sbjct: 557 DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD 616
Query: 506 EEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET---CQK 562
EEKLA T+ QK V E ++ +Y + S++ FSS ++ +
Sbjct: 617 EEKLAVTN--QKWTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEY 673
Query: 563 MEEDGSTV-----------LGLLESSAEKAPVSVS 586
ME+ GS++ L L+ +++++PV S
Sbjct: 674 MEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSS 708
Score = 42.7 bits (99), Expect = 0.001
Identities = 46/167 (27%), Positives = 73/167 (43%), Gaps = 14/167 (8%)
Query: 267 SPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVELGEE---SRSSPLKLEFD 323
SP+ D ++SP+ D +P DL+ SS D ++ + RSS + F+
Sbjct: 41 SPDHRDASSSPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFE 100
Query: 324 FTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPVARDGPLSQTSSK 383
E T ++A A P + P++ + G T PV DGP S S +
Sbjct: 101 TPESTTPVKAPPAPPPPPPEVIPE---PEVSTQPPPEEPGCGSETVPVP-DGPRSD-SVE 155
Query: 384 PDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFK 430
P + S SF+ +V P++S G+Y+ D DN E +D F+
Sbjct: 156 GSPFRPPSHSFS-----AVFDEDKPIASSGTYNLDFDNI-ELVDTFQ 196
>gi|11119414 transforming, acidic coiled-coil containing protein 2
isoform d [Homo sapiens]
Length = 1026
Score = 306 bits (785), Expect = 4e-83
Identities = 279/891 (31%), Positives = 410/891 (46%), Gaps = 146/891 (16%)
Query: 27 AGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAG 86
A + + G+PE + S SS S T + P + + P+
Sbjct: 169 ASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPT---ET 225
Query: 87 PGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKI 146
P K + QE DE+ + E +S+T ++ ++ E P A+ E P
Sbjct: 226 PPVKETQ-QEPDEESLVPSGENLASETKTESAKTEGPSPAL-------LEETPLEPAVGP 277
Query: 147 SIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSS---------PPDALQDEAMT 197
P E+ + A G + + V K LP + P D+ E
Sbjct: 278 KAACPLDSESAEGVVPPASGGGRVQNS--PPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP 335
Query: 198 EGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKP-KPVPLRK---KAIGGEFSDTNAA 253
+ V LE D + ++ E P + +KP +PLR+ K + +T A+
Sbjct: 336 AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS 395
Query: 254 VEGTP-------LPKASYHFSPEELDE-NTSPLLGDARFQKSPPDLKETPGTLSSDTNDS 305
+P + K +Y F ++ D+ N +P ++ Q+SP L + DT D
Sbjct: 396 PPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQSYNFDPDTCDE 454
Query: 306 GVE---LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTP-KIQKDGISKS 361
V+ ++ SSP K F +EA L + TP K + KS
Sbjct: 455 SVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKS 514
Query: 362 AGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGS---HSVLQNSPPLSSEGSYHFD 418
+ PLS S+ DP+ +P P S H+ + ++++
Sbjct: 515 P----------KRSPLSDPPSQ-DPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 563
Query: 419 PDNFDESMDPFKPT---TTLTSSDFCSPT-----------------GNHVNEILESPKKA 458
D + D +P+ T + + F SPT G+ + + ++PKK
Sbjct: 564 VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 623
Query: 459 KSRLI-------------------TSGCKVKKHETQSLALDACSRDEGAVISQISDISNR 499
L+ + C E ++ ++++ V ++ N+
Sbjct: 624 ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAP--NQ 681
Query: 500 DGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEY------FECSNVPVSTINH------A 547
+ H EK + QK A G P E +E F ++ +S + H A
Sbjct: 682 ESHLQVPEKSS-----QKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGA 736
Query: 548 FSSSEAGIEKET----CQKMEEDGSTVLGLLES--------------------SAEKAPV 583
E + ++ QK++E+ + +E+ +A V
Sbjct: 737 LDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDV 796
Query: 584 SVSCGG----------ESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQ 633
S+S E P G+ + D + L + R EIITKE E +EWK KYEE+R+
Sbjct: 797 SISKTALYSRIGTAEVEKPA-GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR 855
Query: 634 EVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFR 693
EV+EMRKIVAEYEKTIAQMIEDEQR S ++ QQL +EKEQALADLNSVE+SL+DLFR
Sbjct: 856 EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR 915
Query: 694 RYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRT 753
RYE +K VLEGF+KNEE LK+CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR
Sbjct: 916 RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG 975
Query: 754 KAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKT 804
KA+ E AA A LRKEQ++V++LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 976 KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1026
Score = 122 bits (306), Expect = 1e-27
Identities = 166/639 (25%), Positives = 261/639 (40%), Gaps = 120/639 (18%)
Query: 50 SLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKC 109
S + SSDSE FETPE+ TP+++P P + P +Q E C
Sbjct: 20 SEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEE---------PGC 70
Query: 110 SSKTCSKP-----SENEVPQQAIDSHSVKNFREEPEH---------DFSKISIVRPFSI- 154
S+T P E SHS +E + DF I +V F
Sbjct: 71 GSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTL 130
Query: 155 --ETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEAD 212
D+ + + T+ +S L S +LQ S EA A A
Sbjct: 131 EPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSL--SLQASDFDGASSSGNPEAVALAP 188
Query: 213 LKAGNSCPELVPSRRSKLRKPKPVPLRKKA-----------------------------I 243
A ++ S + +KP+P L+KK +
Sbjct: 189 -DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENL 247
Query: 244 GGEFSDTNAAVEG--------TPL-----PKASYHFSPEELDENTSPLLGDARFQKSPPD 290
E +A EG TPL PKA+ E + P G R Q SPP
Sbjct: 248 ASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPV 307
Query: 291 LKET-PGTLSSDT-----NDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALP---RKL 341
++T P T + + +DSG + ++ ++LEFD++ED + + ++ P +K+
Sbjct: 308 GRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 367
Query: 342 GRKLGSTL---TPKIQKD----GISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSF 394
G+K + + PK++K + ++ P +P D P+++ + D +W+ P+F
Sbjct: 368 GKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEP--NDIPIAKGTYTFDIDKWDDPNF 425
Query: 395 NPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHV------ 448
NPF S S +Q SP L + SY+FDPD DES+DPFK ++ SS SP +
Sbjct: 426 NPFSSTSKMQESPKLPQQ-SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAME 484
Query: 449 -----NEILESP-KKAKSRLITSGCKVKKHETQSLALDACSRD-EGAVISQISDISNRDG 501
+ L P KK K+ L T +VKK +S D S+D A + + +
Sbjct: 485 ANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVV 544
Query: 502 HATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET-- 559
HATDEEKLA T+ QK V E ++ +Y + S++ FSS ++
Sbjct: 545 HATDEEKLAVTN--QKWTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRNSY 601
Query: 560 -CQKMEEDGSTV-----------LGLLESSAEKAPVSVS 586
+ ME+ GS++ L L+ +++++PV S
Sbjct: 602 EIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSS 640
>gi|5454102 transforming, acidic coiled-coil containing protein 3
[Homo sapiens]
Length = 838
Score = 240 bits (612), Expect = 4e-63
Identities = 233/775 (30%), Positives = 346/775 (44%), Gaps = 119/775 (15%)
Query: 82 LGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSK-PSENEVPQQAIDSHSVKNFREEPE 140
LG A P S S E+ +A++ CSS + S SEN++ S S + EE
Sbjct: 129 LGDASPAFGSGSSSESGPGALADL--DCSSSSQSPGSSENQMVSPGKVSGSPEQAVEENL 186
Query: 141 HDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGS 200
+S V P S +D C T KA P ++E E
Sbjct: 187 SSYSLDRRVTPASETLEDP--------------CRTESQHKA---ETPHGAEEECKAETP 229
Query: 201 MGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPV----PLRKKAIGGEFSDTNAAVEG 256
G AE + + G C + PK PL+ + GE A V G
Sbjct: 230 HG------AEEECRHGGVCAPAAVATSPPGAIPKEACGGAPLQ--GLPGEALGCPAGV-G 280
Query: 257 TPLPK------ASYHFSPEELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVELG 310
TP+P H S E T+ L+ TLS + ++
Sbjct: 281 TPVPADGTQTLTCAHTSAPESTAPTNHLVAGRAM------------TLSPQEEVAAGQMA 328
Query: 311 EESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDP 370
SRS P+KLEFD ++ G R PR+LG + G L P ++K + + ++ +
Sbjct: 329 SSSRSGPVKLEFDVSD--GATSKRAPPPRRLGERSG--LKPPLRKAAVRQQKAPQEVEED 384
Query: 371 VARDG-------PLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFD 423
R G P S+ S D + + P+F PFG + G P
Sbjct: 385 DGRSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGGDT---------KSGCSEAQPPESP 435
Query: 424 ESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVKKHETQSLALDACS 483
E+ L + G +++ L S + ++ + E++ AL++ S
Sbjct: 436 ETRLGQPAAEQLHAGPATEEPGPCLSQQLHSASAEDTPVVQLAAETPTAESKERALNSAS 495
Query: 484 ---------------RDEGAVISQISDISNRD-------GHATDEEKLASTSCGQKSA-- 519
+G ++ + S RD G D + TS ++SA
Sbjct: 496 TSLPTSCPGSEPVPTHQQGQPALELKEESFRDPAEVLGTGAEVDYLEQFGTSSFKESALR 555
Query: 520 --GAEVKGEPEEDLEYFECSNVPVSTIN---HAFSSSEAGIEKETCQKMEEDGSTVLGLL 574
+K +P L VPV+T H + + +G +E + +E D LG L
Sbjct: 556 KQSLYLKFDPL--LRDSPGRPVPVATETSSMHGANETPSGRPREA-KLVEFD---FLGAL 609
Query: 575 ESSAEKAPVSVSCGGESPL------DGICLSESDKTAVLTLIREEIITKEIEANEWKKKY 628
+ P V G PL D + S+ D AV+ +EE E + +
Sbjct: 610 DIPVPGPPPGVPAPGGPPLSTGPIVDLLQYSQKDLDAVVKATQEE-------NRELRSRC 662
Query: 629 EETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSL 688
EE + LE+ KI+ +E+ + Q +E+ Q+ S+ Q++ EK+Q DLNS+E+S
Sbjct: 663 EELHGKNLELGKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSF 722
Query: 689 SDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEI 748
SDLF+R+E K V+EG++KNEE+LKKC +DYLAR+ QE QRYQALK HAEEKL ANEEI
Sbjct: 723 SDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHAEEKLQLANEEI 782
Query: 749 AQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGK 803
AQVR+KA+AE+ AL A LRKEQM+++SLE+ ++QK +E EELT+ICD+LI+K+ K
Sbjct: 783 AQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELTRICDDLISKMEK 837
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 56.2 bits (134), Expect = 1e-07
Identities = 49/206 (23%), Positives = 102/206 (49%), Gaps = 23/206 (11%)
Query: 610 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDE--QRTSMTSQKSF 667
+ +E+ +K E + KK+ ++ E+ E +K + + + Q IE E ++ S +QK
Sbjct: 238 LNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMRE-QQQIEKEIKEKDSELNQKRP 296
Query: 668 QQLTMEKEQA--LADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQ 725
Q + ++ + + L + ++SL + + Y+ KG ++ +K +++K Q++ R+++
Sbjct: 297 QYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEE 356
Query: 726 EEQ--------------RYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQM 771
E Q +Y LK A ++ +E+ + KA+ L +E+
Sbjct: 357 ESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDL---EERK 413
Query: 772 KVESLERALQQKNQEIEELTKICDEL 797
KVE+ E ++QK +EIEE K ++L
Sbjct: 414 KVET-EAKIKQKLREIEENQKRIEKL 438
Score = 37.7 bits (86), Expect = 0.043
Identities = 45/197 (22%), Positives = 80/197 (40%), Gaps = 43/197 (21%)
Query: 601 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTS 660
S K L ++ + + + K +E +E+L + K E+ E+R
Sbjct: 306 SHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEF----------EERME 355
Query: 661 MTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYL 720
SQ + LT+E+ Q ++Y LK EEA K+
Sbjct: 356 EESQSQGRDLTLEENQV---------------KKYHRLK---------EEASKRA----- 386
Query: 721 ARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERAL 780
A + QE +++ + +++LD EE +V T+AK + + + Q ++E LE +
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDL--EERKKVETEAKIKQKLRE--IEENQKRIEKLEEYI 442
Query: 781 QQKNQEIEELTKICDEL 797
Q +EE K+ EL
Sbjct: 443 TTSKQSLEEQKKLEGEL 459
Score = 34.3 bits (77), Expect = 0.47
Identities = 39/196 (19%), Positives = 84/196 (42%), Gaps = 35/196 (17%)
Query: 600 ESDKTAVLTLIREEIITK-EIEANEWKKKYEETR--QEVLEMRKIVAEYEKTIAQMIEDE 656
E +K +L R ++ + +E+ K E T +E+ ++ EY+K +M++ E
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAE 179
Query: 657 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA 716
+ T + + + E+++A + +R Y+ LK
Sbjct: 180 EDTQFNYHRK-KNIAAERKEAKQEKEEADR--------YQRLK----------------- 213
Query: 717 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVR---TKAKAESAALHAGLRKEQMKV 773
D + R + + Q ++ H E +++K N+E+A K K + L++++ ++
Sbjct: 214 -DEVVRAQVQLQLFKLY--HNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKEL 270
Query: 774 ESLERALQQKNQEIEE 789
+ R QQ +EI+E
Sbjct: 271 GKMMREQQQIEKEIKE 286
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 55.5 bits (132), Expect = 2e-07
Identities = 44/198 (22%), Positives = 100/198 (50%), Gaps = 10/198 (5%)
Query: 610 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 669
++++I E+ + +K+ T +V + + +A ++ IA++ ++++ Q++
Sbjct: 952 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDD 1011
Query: 670 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQR 729
L +E+++ +NS+ +S L ++ ++L+G LE KK L++ + +K ++
Sbjct: 1012 LQVEEDK----VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1067
Query: 730 YQAL---KIHAEEKLDKANEEIAQVRTKAKAE---SAALHAGLRKEQMKVESLERALQQK 783
L K+ EEKL K +I Q +K + E + L L++ Q ++E LE L+ +
Sbjct: 1068 IMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAE 1127
Query: 784 NQEIEELTKICDELIAKL 801
++ K+ +L +L
Sbjct: 1128 RTARAKVEKLRSDLSREL 1145
Score = 46.6 bits (109), Expect = 9e-05
Identities = 122/594 (20%), Positives = 226/594 (38%), Gaps = 88/594 (14%)
Query: 270 ELDENTSPLLGDARFQKSPPDLKETPGTLSSDTNDSGVELGEESRS------SPLKLEFD 323
ELD+ TS + + K+ +L++ TL N+ V+L E RS KL+ +
Sbjct: 1229 ELDDVTSNM---EQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTE 1285
Query: 324 FTEDTGNIEARKALPRKLGR-KLGST-----LTPKIQKDGISKSAGLEQPTDPVARDGPL 377
E +E ++AL +L R KL T L +++++G +K+A L D L
Sbjct: 1286 NGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNA-LAHALQSARHDCDL 1344
Query: 378 SQTSSKPDPSQWESPSFNPFGSHSVLQ--NSPPLSSEGSYHFDPDNFDESMDPFKPTTTL 435
+ Q+E + VL NS Y D E ++ K
Sbjct: 1345 LR-------EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQ 1397
Query: 436 TSSDFCSPTGNHVNEILESPKKAKSRLITS----GCKVKKHETQSLALDACSRDEGAVIS 491
D VN S +K K RL V++ + ALD R+ +++
Sbjct: 1398 RLQD-AEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILA 1456
Query: 492 QISDISNRDGHATDEEKLASTSCGQKSAGAEV---KGEPEEDLEYFECSNVPVSTINHAF 548
+ + + + +L S+ +S E+ K EE LE+ E +
Sbjct: 1457 EW-----KQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEI 1511
Query: 549 SS-----SEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDK 603
S E G +K+ + L+S+ E+A S+ E I ++ +
Sbjct: 1512 SDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASL----EHEEGKILRAQLEF 1567
Query: 604 TAVLTLIREEIITKEIEANEWKKKYEE--------------TRQEVLEMRKIVAEYEKTI 649
+ I ++ K+ E + K+ ++ +R EVL ++K + +
Sbjct: 1568 NQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEM 1627
Query: 650 AQMIEDEQRTSMTSQK---SFQQLTMEKEQALAD-----------LNSVERSLSDLFRRY 695
+ R + +QK S Q L + + L D + VER + L
Sbjct: 1628 EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL 1687
Query: 696 ENLKGVLEGFKKNEEALKKCAQDYLARVK----------QEEQRYQALKIHAEEKLDKAN 745
E L+ V+E +++ + ++ + RV+ ++++ ++ + ++++A
Sbjct: 1688 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAV 1747
Query: 746 EEIAQVRTKAK---AESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDE 796
+E KAK ++A + L+KEQ LER + Q I++L DE
Sbjct: 1748 QECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDE 1801
Score = 42.0 bits (97), Expect = 0.002
Identities = 96/418 (22%), Positives = 175/418 (41%), Gaps = 77/418 (18%)
Query: 452 LESPKKAKSRLITSGCKVKKHETQSLA-LDACSRDEGAVISQISDISNRDG----HATDE 506
LES +K L T K+K +SL L+ R+ + +ISD++ + G + +
Sbjct: 1469 LESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHEL 1528
Query: 507 EKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEE- 565
EK+ +K E E LE+ E + F+ +A IE++ +K EE
Sbjct: 1529 EKVRKQLEVEKLELQSALEEAEASLEHEEGK---ILRAQLEFNQIKAEIERKLAEKDEEM 1585
Query: 566 -----DGSTVLGLLESSA--------EKAPVSVSCGGESPLDGICLSESDKTA------- 605
+ V+ L++S E V G+ I LS +++ A
Sbjct: 1586 EQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1645
Query: 606 --VLTLIREEIITKE--IEANEWKKK---YEETRQEVL-----EMRKIVAEYEKTIA--- 650
+ +L+++ I + + AN+ K+ E R +L E+R +V + E++
Sbjct: 1646 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1705
Query: 651 -QMIEDEQR--------TSMTSQKS-----FQQLTMEKEQALADLNSVE----RSLSDLF 692
++IE +R TS+ +QK QL E E+A+ + + E ++++D
Sbjct: 1706 QELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAA 1765
Query: 693 RRYENLK------GVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANE 746
E LK LE KKN E K Q L +E ALK +++L K
Sbjct: 1766 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL-----DEAEQIALK-GGKKQLQKLEA 1819
Query: 747 EIAQVRTKAKAE---SAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKL 801
+ ++ + +AE +A G+RK + +++ L ++ + + L + D+L K+
Sbjct: 1820 RVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKV 1877
Score = 41.6 bits (96), Expect = 0.003
Identities = 41/194 (21%), Positives = 85/194 (43%), Gaps = 33/194 (17%)
Query: 623 EWKKKYEETRQEV-----------LEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLT 671
EWK+KYEE++ E+ E+ K+ YE+++ + +E +R + Q+ LT
Sbjct: 1457 EWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL-EHLETFKRENKNLQEEISDLT 1515
Query: 672 MEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQ 731
+ + +++ +E+ L L+ LE EA + + + R + E +
Sbjct: 1516 EQLGEGGKNVHELEKVRKQLEVEKLELQSALE----EAEASLEHEEGKILRAQLE---FN 1568
Query: 732 ALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELT 791
+K E KL + +EE+ Q + R Q V+SL+ +L + + E+
Sbjct: 1569 QIKAEIERKLAEKDEEMEQAK--------------RNHQRVVDSLQTSLDAETRSRNEVL 1614
Query: 792 KICDELIAKLGKTD 805
++ ++ L + +
Sbjct: 1615 RVKKKMEGDLNEME 1628
Score = 39.3 bits (90), Expect = 0.015
Identities = 71/361 (19%), Positives = 139/361 (38%), Gaps = 53/361 (14%)
Query: 448 VNEILESPKK------AKSRLITSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDG 501
+NE LE ++ AK R + C K + L L ++ ++ + + N
Sbjct: 924 MNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE-NKVKNLTE 982
Query: 502 HATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVST----INHAFSSSEAGIEK 557
+++ + +K A E + +DL+ E +S + E +E+
Sbjct: 983 EMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQ 1042
Query: 558 ETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITK 617
E +M+ LE + K + ES +D E+DK + E++ K
Sbjct: 1043 EKKVRMD---------LERAKRKLEGDLKLTQESIMD----LENDKLQ----LEEKLKKK 1085
Query: 618 EIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQA 677
E + N+ K E+ + L+++K + E + I ++ E+E T++
Sbjct: 1086 EFDINQQNSKIEDEQVLALQLQKKLKENQARIEEL-EEELEAERTARAK----------- 1133
Query: 678 LADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHA 737
VE+ SDL R E + ++ EEA + K+ E +Q ++
Sbjct: 1134 ------VEKLRSDLSRELEEIS------ERLEEA-GGATSVQIEMNKKREAEFQKMRRDL 1180
Query: 738 EEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDEL 797
EE + A +R K A L + Q + LE+ + E++++T +++
Sbjct: 1181 EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1240
Query: 798 I 798
I
Sbjct: 1241 I 1241
Score = 34.7 bits (78), Expect = 0.36
Identities = 45/185 (24%), Positives = 78/185 (42%), Gaps = 39/185 (21%)
Query: 627 KYEETRQEVLEMR----KIVAEYEKTIAQMIE-DEQRTSMTSQKSFQQLTMEKEQALADL 681
K ET +E+ M+ +I EK+ A+ E +E+ S+ +K+ QL ++ EQ +L
Sbjct: 843 KSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD--NL 900
Query: 682 NSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKL 741
N E L + L+ A+VK+ +R E
Sbjct: 901 NDAEERCDQLIKNKIQLE---------------------AKVKEMNERL--------EDE 931
Query: 742 DKANEEIAQVRTKAKAESAALHAGLRKEQM---KVESLERALQQKNQEIEELTKICDELI 798
++ N E+ + K + E + L + ++ KVE + A + K + + E DE+I
Sbjct: 932 EEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 991
Query: 799 AKLGK 803
AKL K
Sbjct: 992 AKLTK 996
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 55.1 bits (131), Expect = 3e-07
Identities = 45/212 (21%), Positives = 106/212 (50%), Gaps = 16/212 (7%)
Query: 590 ESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYE----ETRQEVLEMRKIVAEY 645
+ +D + S S+KTA + I T+++E + K + E QE+L K V+E
Sbjct: 1248 QETIDELRRSVSEKTAQI------INTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSET 1301
Query: 646 EKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGF 705
++T+ ++ ++++ + ++ ME+ + + + L + +NLK + E
Sbjct: 1302 QETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEAL 1361
Query: 706 KKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAG 765
+ + LK+ ++ LA++ QE Q Q ++ +EK ++ + ++++ +SA L
Sbjct: 1362 EVKHDQLKEHIRETLAKI-QESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALL--- 1417
Query: 766 LRKEQMKVESLERALQQKNQEIEELTKICDEL 797
+ ++++ L + LQ+ + E++ + K D+L
Sbjct: 1418 --RIEIEMLGLSKRLQESHDEMKSVAKEKDDL 1447
Score = 45.8 bits (107), Expect = 2e-04
Identities = 49/224 (21%), Positives = 105/224 (46%), Gaps = 36/224 (16%)
Query: 589 GESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT 648
G+ P D +C E + +T +++E+ KE+E NE R+EV+ + ++ K+
Sbjct: 706 GKVPKDLLCNLELE--GKITDLQKEL-NKEVEENE------ALREEVILLSEL-----KS 751
Query: 649 IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN 708
+ +E ++ + +T EK++ S++ + ++G+LE K
Sbjct: 752 LPSEVERLRKEIQDKSEELHIITSEKDKLF----------SEVVHKESRVQGLLEEIGKT 801
Query: 709 EEALKKCAQDYLARVKQEEQRYQALKIHAEEKL-------DKANEEIAQVRTKAKAESAA 761
++ L +Y + QE Q ++ L + E+K ++ N+EI + +A+ ++
Sbjct: 802 KDDLATTQSNYKS-TDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSS 860
Query: 762 LHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 805
L G K ++ ++ E LQ+K +E++E ++L +L D
Sbjct: 861 L--GALKTELSYKTQE--LQEKTREVQERLNEMEQLKEQLENRD 900
Score = 36.2 bits (82), Expect = 0.12
Identities = 46/204 (22%), Positives = 93/204 (45%), Gaps = 16/204 (7%)
Query: 601 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKI--VAEYEKTIAQMIEDE-- 656
++K + ++E+ E EA E K K ++ Q + E+ + + ++ + Q +E+E
Sbjct: 519 TEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELS 578
Query: 657 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA 716
+ + +K Q ++K Q D +E DL E++ E K+ ++ L A
Sbjct: 579 SKVELLREKEDQ---IKKLQEYIDSQKLENIKMDLSYSLESI----EDPKQMKQTLFD-A 630
Query: 717 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESL 776
+ K+E ++ + +EK+ + Q+ + + L A K++M+V+ L
Sbjct: 631 ETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEA---KKKMQVD-L 686
Query: 777 ERALQQKNQEIEELTKICDELIAK 800
E+ LQ EI +LT + D + K
Sbjct: 687 EKELQSAFNEITKLTSLIDGKVPK 710
Score = 34.3 bits (77), Expect = 0.47
Identities = 42/216 (19%), Positives = 89/216 (41%), Gaps = 26/216 (12%)
Query: 599 SESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQM---IED 655
SES+ ++ T +++++ E ++ +++ TR ++ +++ + + I Q+ +
Sbjct: 2247 SESEFPSIKTEF-QQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNN 2305
Query: 656 EQRTSMTSQKSFQQ--LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGF-------- 705
M F++ T+ KE DL S++ LF+ Y+ LK L
Sbjct: 2306 RIIAIMNESTEFEERSATISKEWE-QDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQ 2364
Query: 706 -KKNEEALKKCAQDYLARVKQEEQRYQALK---IHAEEKLDKANEE-------IAQVRTK 754
KN + Q ++++ E K +H E K+ K +E IA+++ K
Sbjct: 2365 DNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAK 2424
Query: 755 AKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 790
+ L Q+ + + + +EIE+L
Sbjct: 2425 VHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDL 2460
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 54.7 bits (130), Expect = 3e-07
Identities = 54/259 (20%), Positives = 119/259 (45%), Gaps = 22/259 (8%)
Query: 551 SEAGIEKETCQKME--EDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLT 608
SE E ++ ++ E E G+ + LL++ + + ++ E D + E + TA+
Sbjct: 708 SEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIA--KEEQEDLLRKRERELTALKG 765
Query: 609 LIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQ 668
++EE+ + + E ++ K++Y+ Q + E + + + +A ++ ++ +
Sbjct: 766 ALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVK 825
Query: 669 QLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQ 728
L E E+ +ER ++ L R+ E+LKG +E K+ + Y ++Q E+
Sbjct: 826 LLQEENEKLQGRSEELERRVAQLQRQIEDLKG-------DEAKAKETLKKYEGEIRQLEE 878
Query: 729 RYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIE 788
+HA K +E R + E A L + + + L L++++++ E
Sbjct: 879 AL----VHAR----KEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKE 930
Query: 789 ELTKICDELIAK---LGKT 804
+L ++ +E+ + LGKT
Sbjct: 931 QLRRLKNEMENERWHLGKT 949
Score = 39.7 bits (91), Expect = 0.011
Identities = 53/255 (20%), Positives = 110/255 (43%), Gaps = 28/255 (10%)
Query: 561 QKMEEDGSTVLGLLESSAEKAP--VSVSCGGESPLDGICLSESDKTAVLTLIREEI---- 614
+K E++ + LE+ E A +S + + L ES++ L ++ E+
Sbjct: 884 RKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENER 943
Query: 615 --ITKEIEA--NEWKKKYEETRQEVLEMRKIVAEYE----KTIAQMIEDEQRTSMTSQKS 666
+ K IE E E +R LE++ + EY+ + +A+M + ++ ++KS
Sbjct: 944 WHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKS 1003
Query: 667 -FQQLTMEKEQALAD--LNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARV 723
+ M+ E L + L +R+ + + + L+ L+ + EA D V
Sbjct: 1004 RLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLV 1063
Query: 724 KQEEQRYQALKIHAE----------EKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKV 773
KQ E + L++ E E++ ++ E++ Q+R + E AA L +++ +
Sbjct: 1064 KQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAA-RQDLECDKISL 1122
Query: 774 ESLERALQQKNQEIE 788
E + L+ + +E
Sbjct: 1123 ERQNKDLKSRIIHLE 1137
Score = 30.8 bits (68), Expect = 5.2
Identities = 37/151 (24%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 663 SQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLAR 722
S + L +K + ++ ++R L + +N+K E + N E L+ + +
Sbjct: 605 STSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEE 664
Query: 723 VKQEEQRYQALKIHAEEKLDKANEEIAQV---RTKAKAESAALHAGLRKEQMKVESLERA 779
+QR + +E +L K EE+ QV R + + E L L + +++S +R+
Sbjct: 665 NSTLQQRLE----ESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRS 720
Query: 780 L-QQKNQEIEELTK----ICDELIAKLGKTD 805
++K IEEL + + D LIAK + D
Sbjct: 721 EDREKGALIEELLQAKQDLQDLLIAKEEQED 751
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 54.3 bits (129), Expect = 4e-07
Identities = 49/196 (25%), Positives = 90/196 (45%), Gaps = 21/196 (10%)
Query: 609 LIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQ 668
L E+++ KE + + + K +++ E E + + D+ + Q++ Q
Sbjct: 443 LSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQL-----DKTKQQHQEQQALQ 497
Query: 669 QLTMEK-EQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEE 727
Q T K +A DL V R + D ++ +NL+ +L+ K+N L+K +D A+++ E
Sbjct: 498 QSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGE 557
Query: 728 QRYQALKIHAEEKLDKANEEIAQVRTKAKAESAA-------LH-------AGLRKEQMKV 773
L +EK E++ Q+ K K +S + LH A LR Q +V
Sbjct: 558 GETAVLN-QLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRV 616
Query: 774 ESLERALQQKNQEIEE 789
SLE ++ + N ++ E
Sbjct: 617 LSLETSVNELNSQLNE 632
Score = 51.2 bits (121), Expect = 4e-06
Identities = 47/212 (22%), Positives = 94/212 (44%), Gaps = 15/212 (7%)
Query: 590 ESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTI 649
E+ L I + S+K ++EE+ E + K ++++ +Q+ E + + + I
Sbjct: 357 ETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEI 416
Query: 650 AQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNE 709
Q+ T ++ +L +++ + L E+ ++DL + L+ L+ N
Sbjct: 417 NQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNS 476
Query: 710 EALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKE 769
L Q L + KQ+ Q QAL+ KL +A ++ QV + + +
Sbjct: 477 TEL----QHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQ-----------IGDK 521
Query: 770 QMKVESLERALQQKNQEIEELTKICDELIAKL 801
K+++LE LQ+ + I L K ++L AK+
Sbjct: 522 DQKIQNLEALLQKSKENISLLEKEREDLYAKI 553
Score = 49.3 bits (116), Expect = 1e-05
Identities = 53/242 (21%), Positives = 108/242 (44%), Gaps = 41/242 (16%)
Query: 601 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLE-----------MRKIVAEYEKTI 649
+D L+ + E++ K + E + + ++T+Q+ E +R+ + E+ +
Sbjct: 456 ADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVL 515
Query: 650 AQMIEDEQRTS------MTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYEN------ 697
Q+ + +Q+ S+++ L E+E A + + E + L + E
Sbjct: 516 RQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQE 575
Query: 698 --------LKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEE---KLDKANE 746
LK E K+ +E L Q+ A ++ + R +L+ E +L+++ E
Sbjct: 576 QVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKE 635
Query: 747 EIAQ--VRTKAKAE-----SAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIA 799
+++Q ++ KAK E AA A Q +++ + ALQ K QE+ ++T D++ A
Sbjct: 636 KVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTA 695
Query: 800 KL 801
KL
Sbjct: 696 KL 697
Score = 44.3 bits (103), Expect = 5e-04
Identities = 42/195 (21%), Positives = 86/195 (44%), Gaps = 1/195 (0%)
Query: 603 KTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMT 662
KTA TL ++ KE + E K ++ ++E K + + +A++ E + R
Sbjct: 1081 KTAKATL-EQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKE 1139
Query: 663 SQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLAR 722
K ++L K +++ ++ +++ + L ++ L+G + K E K+ Q +
Sbjct: 1140 ITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQ 1199
Query: 723 VKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQ 782
VK+EE+ + I E KL +E K + A L + + ++++ Q
Sbjct: 1200 VKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQS 1259
Query: 783 KNQEIEELTKICDEL 797
+ + EL K D+L
Sbjct: 1260 SQRRVSELEKQTDDL 1274
Score = 43.1 bits (100), Expect = 0.001
Identities = 35/171 (20%), Positives = 72/171 (42%), Gaps = 1/171 (0%)
Query: 620 EANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALA 679
+ NE K+K + ++ +++ E D Q T+Q + Q E +
Sbjct: 629 QLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITT 688
Query: 680 DLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEE 739
L+ V L D L+ L+ +K+ +L++ ++ ++K+ E +K E+
Sbjct: 689 QLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQ 748
Query: 740 KLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 790
L ++ Q+ T + + L L E+ V S LQ+K++ +E +
Sbjct: 749 ALQDLQQQ-RQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESI 798
Score = 41.2 bits (95), Expect = 0.004
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 24/193 (12%)
Query: 622 NEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADL 681
NE K+ E+ ++++ ++ E + + Q E E + ++ Q+L EKE+
Sbjct: 962 NELKQSSEQKKKQIEALQ---GELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQ 1018
Query: 682 NSVERS-------LSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA---RVKQEEQRYQ 731
N+ E+S SD + R L + K EE L +D ++ ++ + + Q
Sbjct: 1019 NNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQ 1078
Query: 732 ALK-IHAEEKLDKANEEIAQVRTKAKA------ESAALHAGLRKEQMKVESLERALQQKN 784
LK A + D A +E Q++ + KA E + L E+ K+ +E + K
Sbjct: 1079 ELKTAKATLEQDSAKKE-QQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIE---EIKC 1134
Query: 785 QEIEELTKICDEL 797
++ +E+TK+ +EL
Sbjct: 1135 RQEKEITKLNEEL 1147
Score = 36.2 bits (82), Expect = 0.12
Identities = 59/345 (17%), Positives = 133/345 (38%), Gaps = 50/345 (14%)
Query: 486 EGAVISQISDISNRDGHATDE--EKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVST 543
E AV++Q+ + ++ + EKL + S K A + + +E + + V +
Sbjct: 559 ETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLS 618
Query: 544 INHAFS--SSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSES 601
+ + + +S+ KE +++ LL SAE A + ++ LD +
Sbjct: 619 LETSVNELNSQLNESKEKVSQLDIQIKAKTELL-LSAEAAKTAQRADLQNHLDTAQNALQ 677
Query: 602 DK-------TAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIE 654
DK T L + ++ K+ ++ + +E +++ L + + E E I ++
Sbjct: 678 DKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEA 737
Query: 655 DEQRTSMTSQKSFQQLTMEKE--------------QALADLNSVERSLSDLFRRYENLKG 700
D + +++ Q L +++ Q + V + DL ++ E L+
Sbjct: 738 DSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALES 797
Query: 701 VLEGFKKNEEALKKCAQDY------------------------LARVKQEEQRYQALKIH 736
+ + K EE + QD+ L +VK E++
Sbjct: 798 IKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELST 857
Query: 737 AEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQ 781
++KL K ++ + +++ + E+ A + + + L+ LQ
Sbjct: 858 VKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQ 902
>gi|45331215 leucine zipper, putative tumor suppressor 2 [Homo
sapiens]
Length = 669
Score = 54.3 bits (129), Expect = 4e-07
Identities = 60/273 (21%), Positives = 109/273 (39%), Gaps = 29/273 (10%)
Query: 549 SSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGI----------CL 598
S S++G + G GLL S +P S SCG SP C+
Sbjct: 269 SHSDSGRSSSSKSTGSLGGRVAGGLLGSGTRASPDSSSCGERSPPPPPPPPSDEALLHCV 328
Query: 599 SES---DKTAVLTLIREEIITKEI--------EANEWKKKYEETRQEVLEMRKIVAEYEK 647
E D+ A L +R+ + E W+++ E R++ + ++
Sbjct: 329 LEGKLRDREAELQQLRDSLDENEATMCQAYEERQRHWQREREALREDCAAQAQRAQRAQQ 388
Query: 648 TIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKK 707
+ + Q+ Q F QL E+EQ ++ER +L R E K +
Sbjct: 389 LLQLQVFQLQQEKRQLQDDFAQLLQEREQLERRCATLEREQRELGPRLEETKWEVCQKSG 448
Query: 708 NEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLR 767
LK+ ++ A + Q+ AL++ E +A +++ R + E+A R
Sbjct: 449 EISLLKQQLKESQAELVQKGSELVALRVALREA--RATLRVSEGRARGLQEAA------R 500
Query: 768 KEQMKVESLERALQQKNQEIEELTKICDELIAK 800
++++E+ + LQ+ QE E+L + +L A+
Sbjct: 501 ARELELEACSQELQRHRQEAEQLREKAGQLDAE 533
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 52.8 bits (125), Expect = 1e-06
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 610 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 669
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 757 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 812
Query: 670 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 726
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 813 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 872
Query: 727 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 784
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 873 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 932
Query: 785 QEIEELTKICDELIA 799
++ E K E+I+
Sbjct: 933 NQLAECKKQHQEVIS 947
Score = 46.6 bits (109), Expect = 9e-05
Identities = 98/468 (20%), Positives = 189/468 (40%), Gaps = 73/468 (15%)
Query: 358 ISKSAGLEQPTDPVARDGPL---SQTSSKPDPSQWESPSFNPFGSHSVLQ----NSPPLS 410
IS+ A L+ PT P D S+ S P + P +P V S PLS
Sbjct: 244 ISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPLS 303
Query: 411 SEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVK 470
+ S F F + + + D S + + +L+ +A + + S + K
Sbjct: 304 GKESVFFAEPPFKAEISSIRE-----NKDRLSDSTTGADSLLDISSEADQQDLLSLLQAK 358
Query: 471 -------KHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEV 523
E Q L A S E +D+S H+T + S +++ +
Sbjct: 359 VASLTLHNKELQD-KLQAKSPKEAE-----ADLSFDSYHSTQTDLGPSLGKPGETSPPDS 412
Query: 524 KGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESS-AEKAP 582
K P +V + ++ + + ++ I Q+++E + LESS AE+
Sbjct: 413 KSSP----------SVLIHSLGKSTTDNDVRI-----QQLQEILQDLQKRLESSEAERKQ 457
Query: 583 VSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIV 642
+ V + +CL+ ++ I E + E + KYEE +EVL ++K
Sbjct: 458 LQVELQSRRA-ELVCLNNTE-------ISENSSDLSQKLKETQSKYEEAMKEVLSVQK-- 507
Query: 643 AEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVL 702
+ ++ E SM + F +L + +E+ ++ +L + R E ++ +
Sbjct: 508 ----QMKLGLVSPE---SMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELE 560
Query: 703 EGFKKNEE--ALKKCAQDYLARVKQEEQRYQAL-------KIHAEEKLDKANEEIAQVRT 753
E + E+ +K ++Y ++ + Y ++ K EK +A EEI +++
Sbjct: 561 EKLVEREKGTVIKPPVEEY----EEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 616
Query: 754 KAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKL 801
K++ A E MK E++ R + + N+++ EL+++ E A+L
Sbjct: 617 TLKSQMTQ-EASDEAEDMK-EAMNRMIDELNKQVSELSQLYKEAQAEL 662
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 602 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 661
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 837 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 888
Query: 662 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 721
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 889 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 939
Query: 722 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 759
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 940 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 980
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 52.8 bits (125), Expect = 1e-06
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 610 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 669
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 746 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 801
Query: 670 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 726
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 802 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 861
Query: 727 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 784
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 862 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 921
Query: 785 QEIEELTKICDELIA 799
++ E K E+I+
Sbjct: 922 NQLAECKKQHQEVIS 936
Score = 46.6 bits (109), Expect = 9e-05
Identities = 98/468 (20%), Positives = 189/468 (40%), Gaps = 73/468 (15%)
Query: 358 ISKSAGLEQPTDPVARDGPL---SQTSSKPDPSQWESPSFNPFGSHSVLQ----NSPPLS 410
IS+ A L+ PT P D S+ S P + P +P V S PLS
Sbjct: 233 ISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPLS 292
Query: 411 SEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVK 470
+ S F F + + + D S + + +L+ +A + + S + K
Sbjct: 293 GKESVFFAEPPFKAEISSIRE-----NKDRLSDSTTGADSLLDISSEADQQDLLSLLQAK 347
Query: 471 -------KHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEV 523
E Q L A S E +D+S H+T + S +++ +
Sbjct: 348 VASLTLHNKELQD-KLQAKSPKEAE-----ADLSFDSYHSTQTDLGPSLGKPGETSPPDS 401
Query: 524 KGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESS-AEKAP 582
K P +V + ++ + + ++ I Q+++E + LESS AE+
Sbjct: 402 KSSP----------SVLIHSLGKSTTDNDVRI-----QQLQEILQDLQKRLESSEAERKQ 446
Query: 583 VSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIV 642
+ V + +CL+ ++ I E + E + KYEE +EVL ++K
Sbjct: 447 LQVELQSRRA-ELVCLNNTE-------ISENSSDLSQKLKETQSKYEEAMKEVLSVQK-- 496
Query: 643 AEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVL 702
+ ++ E SM + F +L + +E+ ++ +L + R E ++ +
Sbjct: 497 ----QMKLGLVSPE---SMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELE 549
Query: 703 EGFKKNEE--ALKKCAQDYLARVKQEEQRYQAL-------KIHAEEKLDKANEEIAQVRT 753
E + E+ +K ++Y ++ + Y ++ K EK +A EEI +++
Sbjct: 550 EKLVEREKGTVIKPPVEEY----EEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 605
Query: 754 KAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKL 801
K++ A E MK E++ R + + N+++ EL+++ E A+L
Sbjct: 606 TLKSQMTQ-EASDEAEDMK-EAMNRMIDELNKQVSELSQLYKEAQAEL 651
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 602 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 661
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 826 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 877
Query: 662 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 721
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 878 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 928
Query: 722 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 759
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 929 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 969
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 52.8 bits (125), Expect = 1e-06
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 610 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 669
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 725 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 780
Query: 670 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 726
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 781 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 840
Query: 727 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 784
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 841 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 900
Query: 785 QEIEELTKICDELIA 799
++ E K E+I+
Sbjct: 901 NQLAECKKQHQEVIS 915
Score = 44.3 bits (103), Expect = 5e-04
Identities = 99/454 (21%), Positives = 186/454 (40%), Gaps = 74/454 (16%)
Query: 358 ISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHF 417
IS+ A L+ PT P Q S P S + G SV PP +E S
Sbjct: 241 ISQDADLKTPTKP-------KQLSDVSSPRSITSTPLS--GKESVFFAEPPFKAEIS--- 288
Query: 418 DPDNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVKKHETQSL 477
+ E+ D +TT S + ++L S +AK +T + E Q
Sbjct: 289 ---SIRENKDRLSDSTTGADSLLDISSEADQQDLL-SLLQAKVASLT----LHNKELQD- 339
Query: 478 ALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECS 537
L A S E +D+S H+T + S +++ + K P
Sbjct: 340 KLQAKSPKEAE-----ADLSFDSYHSTQTDLGPSLGKPGETSPPDSKSSP---------- 384
Query: 538 NVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESS-AEKAPVSVSCGGESPLDGI 596
+V + ++ + + ++ I Q+++E + LESS AE+ + V + +
Sbjct: 385 SVLIHSLGKSTTDNDVRI-----QQLQEILQDLQKRLESSEAERKQLQVELQSRRA-ELV 438
Query: 597 CLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDE 656
CL+ ++ I E + E + KYEE +EVL ++K + ++ E
Sbjct: 439 CLNNTE-------ISENSSDLSQKLKETQSKYEEAMKEVLSVQK------QMKLGLVSPE 485
Query: 657 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEE--ALKK 714
SM + F +L + +E+ ++ +L + R E ++ + E + E+ +K
Sbjct: 486 ---SMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKP 542
Query: 715 CAQDYLARVKQEEQRYQAL-------KIHAEEKLDKANEEIAQVRTKAKAESAALHAGLR 767
++Y ++ + Y ++ K EK +A EEI +++ K++ A
Sbjct: 543 PVEEY----EEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDE 597
Query: 768 KEQMKVESLERALQQKNQEIEELTKICDELIAKL 801
E MK E++ R + + N+++ EL+++ E A+L
Sbjct: 598 AEDMK-EAMNRMIDELNKQVSELSQLYKEAQAEL 630
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 602 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 661
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 805 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 856
Query: 662 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 721
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 857 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 907
Query: 722 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 759
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 908 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 948
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 52.8 bits (125), Expect = 1e-06
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 610 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 669
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 754 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 809
Query: 670 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 726
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 810 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 869
Query: 727 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 784
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 870 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 929
Query: 785 QEIEELTKICDELIA 799
++ E K E+I+
Sbjct: 930 NQLAECKKQHQEVIS 944
Score = 46.6 bits (109), Expect = 9e-05
Identities = 98/468 (20%), Positives = 189/468 (40%), Gaps = 73/468 (15%)
Query: 358 ISKSAGLEQPTDPVARDGPL---SQTSSKPDPSQWESPSFNPFGSHSVLQ----NSPPLS 410
IS+ A L+ PT P D S+ S P + P +P V S PLS
Sbjct: 241 ISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPLS 300
Query: 411 SEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVK 470
+ S F F + + + D S + + +L+ +A + + S + K
Sbjct: 301 GKESVFFAEPPFKAEISSIRE-----NKDRLSDSTTGADSLLDISSEADQQDLLSLLQAK 355
Query: 471 -------KHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEV 523
E Q L A S E +D+S H+T + S +++ +
Sbjct: 356 VASLTLHNKELQD-KLQAKSPKEAE-----ADLSFDSYHSTQTDLGPSLGKPGETSPPDS 409
Query: 524 KGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESS-AEKAP 582
K P +V + ++ + + ++ I Q+++E + LESS AE+
Sbjct: 410 KSSP----------SVLIHSLGKSTTDNDVRI-----QQLQEILQDLQKRLESSEAERKQ 454
Query: 583 VSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIV 642
+ V + +CL+ ++ I E + E + KYEE +EVL ++K
Sbjct: 455 LQVELQSRRA-ELVCLNNTE-------ISENSSDLSQKLKETQSKYEEAMKEVLSVQK-- 504
Query: 643 AEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVL 702
+ ++ E SM + F +L + +E+ ++ +L + R E ++ +
Sbjct: 505 ----QMKLGLVSPE---SMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELE 557
Query: 703 EGFKKNEE--ALKKCAQDYLARVKQEEQRYQAL-------KIHAEEKLDKANEEIAQVRT 753
E + E+ +K ++Y ++ + Y ++ K EK +A EEI +++
Sbjct: 558 EKLVEREKGTVIKPPVEEY----EEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 613
Query: 754 KAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKL 801
K++ A E MK E++ R + + N+++ EL+++ E A+L
Sbjct: 614 TLKSQMTQ-EASDEAEDMK-EAMNRMIDELNKQVSELSQLYKEAQAEL 659
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 602 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 661
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 834 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 885
Query: 662 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 721
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 886 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 936
Query: 722 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 759
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 937 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 977
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 52.8 bits (125), Expect = 1e-06
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 610 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 669
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 754 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 809
Query: 670 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 726
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 810 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 869
Query: 727 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 784
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 870 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 929
Query: 785 QEIEELTKICDELIA 799
++ E K E+I+
Sbjct: 930 NQLAECKKQHQEVIS 944
Score = 46.6 bits (109), Expect = 9e-05
Identities = 98/468 (20%), Positives = 189/468 (40%), Gaps = 73/468 (15%)
Query: 358 ISKSAGLEQPTDPVARDGPL---SQTSSKPDPSQWESPSFNPFGSHSVLQ----NSPPLS 410
IS+ A L+ PT P D S+ S P + P +P V S PLS
Sbjct: 241 ISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPLS 300
Query: 411 SEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVK 470
+ S F F + + + D S + + +L+ +A + + S + K
Sbjct: 301 GKESVFFAEPPFKAEISSIRE-----NKDRLSDSTTGADSLLDISSEADQQDLLSLLQAK 355
Query: 471 -------KHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEV 523
E Q L A S E +D+S H+T + S +++ +
Sbjct: 356 VASLTLHNKELQD-KLQAKSPKEAE-----ADLSFDSYHSTQTDLGPSLGKPGETSPPDS 409
Query: 524 KGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESS-AEKAP 582
K P +V + ++ + + ++ I Q+++E + LESS AE+
Sbjct: 410 KSSP----------SVLIHSLGKSTTDNDVRI-----QQLQEILQDLQKRLESSEAERKQ 454
Query: 583 VSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIV 642
+ V + +CL+ ++ I E + E + KYEE +EVL ++K
Sbjct: 455 LQVELQSRRA-ELVCLNNTE-------ISENSSDLSQKLKETQSKYEEAMKEVLSVQK-- 504
Query: 643 AEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVL 702
+ ++ E SM + F +L + +E+ ++ +L + R E ++ +
Sbjct: 505 ----QMKLGLVSPE---SMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELE 557
Query: 703 EGFKKNEE--ALKKCAQDYLARVKQEEQRYQAL-------KIHAEEKLDKANEEIAQVRT 753
E + E+ +K ++Y ++ + Y ++ K EK +A EEI +++
Sbjct: 558 EKLVEREKGTVIKPPVEEY----EEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 613
Query: 754 KAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKL 801
K++ A E MK E++ R + + N+++ EL+++ E A+L
Sbjct: 614 TLKSQMTQ-EASDEAEDMK-EAMNRMIDELNKQVSELSQLYKEAQAEL 659
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 602 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 661
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 834 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 885
Query: 662 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 721
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 886 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 936
Query: 722 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 759
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 937 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 977
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 52.8 bits (125), Expect = 1e-06
Identities = 39/195 (20%), Positives = 104/195 (53%), Gaps = 9/195 (4%)
Query: 610 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 669
++E + +KE+E + +K+ E + + + + YEK + + E S+ + K ++
Sbjct: 754 LKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSL---ESEVSVLASK-LKE 809
Query: 670 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN-EEALKKC--AQDYLARVKQE 726
EKE+ +++ + +S + R EN++ +L+ ++ E L+K AQ+ LA +K+
Sbjct: 810 SVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRY 869
Query: 727 EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALH--AGLRKEQMKVESLERALQQKN 784
+ L+ ++K+++ ++E+ +++ + S + + +++ ++E+L++ ++Q
Sbjct: 870 AESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ 929
Query: 785 QEIEELTKICDELIA 799
++ E K E+I+
Sbjct: 930 NQLAECKKQHQEVIS 944
Score = 46.6 bits (109), Expect = 9e-05
Identities = 98/468 (20%), Positives = 189/468 (40%), Gaps = 73/468 (15%)
Query: 358 ISKSAGLEQPTDPVARDGPL---SQTSSKPDPSQWESPSFNPFGSHSVLQ----NSPPLS 410
IS+ A L+ PT P D S+ S P + P +P V S PLS
Sbjct: 241 ISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPLS 300
Query: 411 SEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKVK 470
+ S F F + + + D S + + +L+ +A + + S + K
Sbjct: 301 GKESVFFAEPPFKAEISSIRE-----NKDRLSDSTTGADSLLDISSEADQQDLLSLLQAK 355
Query: 471 -------KHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEV 523
E Q L A S E +D+S H+T + S +++ +
Sbjct: 356 VASLTLHNKELQD-KLQAKSPKEAE-----ADLSFDSYHSTQTDLGPSLGKPGETSPPDS 409
Query: 524 KGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESS-AEKAP 582
K P +V + ++ + + ++ I Q+++E + LESS AE+
Sbjct: 410 KSSP----------SVLIHSLGKSTTDNDVRI-----QQLQEILQDLQKRLESSEAERKQ 454
Query: 583 VSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIV 642
+ V + +CL+ ++ I E + E + KYEE +EVL ++K
Sbjct: 455 LQVELQSRRA-ELVCLNNTE-------ISENSSDLSQKLKETQSKYEEAMKEVLSVQK-- 504
Query: 643 AEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVL 702
+ ++ E SM + F +L + +E+ ++ +L + R E ++ +
Sbjct: 505 ----QMKLGLVSPE---SMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELE 557
Query: 703 EGFKKNEE--ALKKCAQDYLARVKQEEQRYQAL-------KIHAEEKLDKANEEIAQVRT 753
E + E+ +K ++Y ++ + Y ++ K EK +A EEI +++
Sbjct: 558 EKLVEREKGTVIKPPVEEY----EEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKD 613
Query: 754 KAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKL 801
K++ A E MK E++ R + + N+++ EL+++ E A+L
Sbjct: 614 TLKSQMTQ-EASDEAEDMK-EAMNRMIDELNKQVSELSQLYKEAQAEL 659
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/163 (21%), Positives = 81/163 (49%), Gaps = 24/163 (14%)
Query: 602 DKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSM 661
+K + TL++ +KE E NE +K+++ ++E+ EM++ Y ++ +++ ED+ +
Sbjct: 834 EKENIQTLLK----SKEQEVNELLQKFQQAQEELAEMKR----YAESSSKLEEDKDKKIN 885
Query: 662 TSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLA 721
K +L ++AL L+ + S S R+ + L+ + + K+ + L +C
Sbjct: 886 EMSKEVTKL----KEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK----- 936
Query: 722 RVKQEEQRYQALKIH----AEEKLDK-ANEEIAQVRTKAKAES 759
KQ ++ ++H + ++D+ + + Q+ T K +S
Sbjct: 937 --KQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQS 977
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 51.6 bits (122), Expect = 3e-06
Identities = 78/382 (20%), Positives = 172/382 (45%), Gaps = 39/382 (10%)
Query: 424 ESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITSGCKV--KKHETQSLALDA 481
E++ K TL +S+ ++E L+ +K K + K+ + + ++L ++
Sbjct: 300 ETIQSHKEQCTLLTSEK-EALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNL-IEQ 357
Query: 482 CSRDEGAVISQISDISNRDGHATDEE--KLASTSCGQKSAGAEVKGEPEEDLEYFECSNV 539
+D+G VI++ + +EE +L S + G E++ + E+
Sbjct: 358 LEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKS------ERA 411
Query: 540 PVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSV----SCGGESPLDG 595
+ A S+++ +E +K++ + + +E ++E+ +S+ S + +D
Sbjct: 412 AFEELEKALSTAQK--TEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDV 469
Query: 596 ICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIED 655
+ S ++ A L + E+ + ++ + E KK + +E E K+ E K+ ++ ++
Sbjct: 470 MKKSSEEQIAKLQKLHEKELARKEQ--ELTKKLQTREREFQEQMKVALE--KSQSEYLKI 525
Query: 656 EQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKG-VLEGFKKNEEALKK 714
Q + ++L ++K+ A L E L DL + E + +LE E +L+K
Sbjct: 526 SQEKEQQESLALEELELQKK---AILTESENKLRDLQQEAETYRTRILE----LESSLEK 578
Query: 715 CAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVE 774
Q+ + + + L +H E + +K N+EI + K K E +L +++ + E
Sbjct: 579 SLQE-------NKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKH--QQDALWTE 629
Query: 775 SLERALQQKNQEIEELTKICDE 796
L+ QQ E+E+L + C++
Sbjct: 630 KLQVLKQQYQTEMEKLREKCEQ 651
Score = 48.9 bits (115), Expect = 2e-05
Identities = 77/353 (21%), Positives = 162/353 (45%), Gaps = 52/353 (14%)
Query: 479 LDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSN 538
++ S A++S+IS +R +E L +C A+++ EE
Sbjct: 1236 INISSSKTNAILSRISHCQHRTTKV--KEALLIKTCTVSELEAQLRQLTEEQ-------- 1285
Query: 539 VPVSTINHAFSSSEAGIEKETCQ--KMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGI 596
+T+N +F + +E++ Q M+ D +++ E+ ++ E
Sbjct: 1286 ---NTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKES--- 1339
Query: 597 CLSE-----SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQ 651
C+++ S+ +TL++EE+ K++E + K+ + + L+ ++E E I+
Sbjct: 1340 CITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQ-LQNSISLSEKEAAISS 1398
Query: 652 MIE--DEQRTSMTSQK---SFQQLTMEKEQ--ALADLNSVERSLSDL-------FRRYEN 697
+ + DE++ + Q SF+ T+ KE+ AL ++ S+ F +++N
Sbjct: 1399 LRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQN 1458
Query: 698 ----LKGVLEGFKKNEEALKKCAQDYLAR--VKQEEQRYQALKIHAEEKLDKANEEIAQV 751
L+ LE K++EA +K Q L + + Q+ +R+ LK E+ K ++ + +
Sbjct: 1459 TVKELQIQLE--LKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNL 1516
Query: 752 RTKAKAESAA---LHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKL 801
T+ K+++A L + ++ +++ESL L+ NQ+ + K EL+ KL
Sbjct: 1517 ETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHK---ELVQKL 1566
Score = 44.3 bits (103), Expect = 5e-04
Identities = 38/129 (29%), Positives = 62/129 (48%), Gaps = 8/129 (6%)
Query: 671 TMEKEQALADLNSVERSLSDLFRRYENL---KGVLEGFKKNEEALKKCAQD----YLARV 723
++ KEQ + L +ERSLS +Y L +L+ KK + + +QD +A +
Sbjct: 133 SLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAEL 192
Query: 724 KQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQK 783
++E Q Q K H +E+ D + EE Q + + + + L LR M V+ L + L Q
Sbjct: 193 REELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVL-KPLPQL 251
Query: 784 NQEIEELTK 792
+ E TK
Sbjct: 252 EPQAEVFTK 260
Score = 43.1 bits (100), Expect = 0.001
Identities = 43/185 (23%), Positives = 88/185 (47%), Gaps = 23/185 (12%)
Query: 624 WKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNS 683
++ K E+ +E + ++I+ E E I QM E ++ K + LT + ++
Sbjct: 888 YESKLEDGNKEQEQTKQILVEKENMILQMREGQK-------KEIEILTQKLSAKEDSIHI 940
Query: 684 VERSLSDLFRRYEN-LKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLD 742
+ F+ E ++ V + K+ +E LKK D A++K+E + AL++ +EK
Sbjct: 941 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELEN-TALELSQKEKQF 999
Query: 743 KA-------------NEEIAQVRTKAKAESAALHAGLRKEQMKVESL-ERALQQKNQEIE 788
A ++ ++++ T K + +L R+E V S+ E+ L Q+ +E++
Sbjct: 1000 NAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQ 1059
Query: 789 ELTKI 793
E+ +I
Sbjct: 1060 EIHEI 1064
Score = 39.3 bits (90), Expect = 0.015
Identities = 67/325 (20%), Positives = 138/325 (42%), Gaps = 33/325 (10%)
Query: 496 ISNRDGHATDEEKLASTSCGQK----SAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSS 551
IS + T++EKL +K S+ E++ + +E L E + H S
Sbjct: 1738 ISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAK----QHEDQSM 1793
Query: 552 EAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIR 611
+++E +K ++ V +E K + E+ D + + +K ++
Sbjct: 1794 IGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILE 1853
Query: 612 EEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEK--TIAQMIEDEQRTSM----TSQK 665
++I KE+++ ++K +EM ++ ++YEK + QM + T + T +K
Sbjct: 1854 QKI--KELDSCLVRQKEVHR----VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEK 1907
Query: 666 SFQQLTMEK--EQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARV 723
S L K A N +E L+ R + L + +K+ L+K Q L +
Sbjct: 1908 SKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEIL 1967
Query: 724 KQE--EQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGL---------RKEQMK 772
K+E ++R + +K E+ K N + Q+ + + A L + ++++
Sbjct: 1968 KKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVE 2027
Query: 773 VESLERALQQKNQEIEELTKICDEL 797
E LE ++ NQ ++++ + D+L
Sbjct: 2028 AELLESHQEETNQLLKKIAEKDDDL 2052
Score = 33.5 bits (75), Expect = 0.81
Identities = 57/297 (19%), Positives = 111/297 (37%), Gaps = 47/297 (15%)
Query: 523 VKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKM-------EEDGSTVLGLLE 575
+K E E + E N+ V + + E +E E+ K+ E+ + + L
Sbjct: 1597 MKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLL 1656
Query: 576 SSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEW-------KKKY 628
S E+ G ES L + ++ + ++ E++ + E +E K
Sbjct: 1657 SQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVA 1716
Query: 629 EETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSL 688
T QE + + V +KT + I QR +K Q++ EKE+ ++ +
Sbjct: 1717 AYTEQEEADSQGCV---QKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQY 1773
Query: 689 SDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEI 748
+ + E+ A KQ E Q++ H +E+L++ N++
Sbjct: 1774 QERLIKLEH-----------------------AEAKQHED--QSMIGHLQEELEEKNKKY 1808
Query: 749 AQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 805
+ + A+ G Q K ++LE + ++E C L K+ + D
Sbjct: 1809 SLI----VAQHVEKEGGKNNIQAK-QNLENVFDDVQKTLQEKELTCQILEQKIKELD 1860
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 51.2 bits (121), Expect = 4e-06
Identities = 55/196 (28%), Positives = 91/196 (46%), Gaps = 24/196 (12%)
Query: 611 REEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKT----------IAQMIEDEQRTS 660
R++++ E++ ++ K QE EM +A E + Q IE+ + T+
Sbjct: 293 RQKLLKLEVD---FEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETN 349
Query: 661 MTSQKSFQQLTMEKEQALAD-LNSVERSLSDLFRRYENL-KGVLEGFKKNEEALKKCAQD 718
QK+ ++L Q L D + E S L ENL K VLE K+EE K +Q
Sbjct: 350 KNLQKAEEEL-----QELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQC 404
Query: 719 YLARVKQEEQRYQALKIHAE-EKLDKANEEIAQVR---TKAKAESAALHAGLRKEQMKVE 774
R K +E+ + + ++ E EKL K E+ ++ +K+K+E LH L KE+ +
Sbjct: 405 RELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTK 464
Query: 775 SLERALQQKNQEIEEL 790
L L+ ++EL
Sbjct: 465 DLLNELEVVKSRVKEL 480
Score = 42.7 bits (99), Expect = 0.001
Identities = 64/291 (21%), Positives = 130/291 (44%), Gaps = 55/291 (18%)
Query: 549 SSSEAGIEKETCQKMEED---GSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTA 605
S SE +K+ + E+D TV L++S E C ++ + LS+ D
Sbjct: 31 SLSEDAKKKKKSNRKEDDVMASGTVKRHLKTSGE-------CERKTK-KSLELSKEDLIQ 82
Query: 606 VLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAE--------------------- 644
+L+++ E+ +E + K E+T+ EVLE AE
Sbjct: 83 LLSIMEGELQAREDVIHMLKT--EKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIG 140
Query: 645 ---YEKTIAQMIEDEQRTSMTSQKSFQQLTMEKE---QALADLNSVERSLSDLFRRYENL 698
YEK I+++ E++ T ++ +QL + ++ + + +L + + +D + ++
Sbjct: 141 EDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDF 200
Query: 699 KGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEK-LDKANEEIAQVRTKA-- 755
+LE + E LKK + ++E+ YQA K K L+K +E+ ++++ A
Sbjct: 201 TNLLE---QERERLKK--------LLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALM 249
Query: 756 KAESAALH-AGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD 805
+ +H L + KV+ L + L+++ ++++ +T E KL K +
Sbjct: 250 LVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLE 300
Score = 37.7 bits (86), Expect = 0.043
Identities = 53/238 (22%), Positives = 96/238 (40%), Gaps = 48/238 (20%)
Query: 612 EEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQ-QL 670
EEI E + E +KK +E E+R V + +K ++++ + E+ S + + Q L
Sbjct: 395 EEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHL 454
Query: 671 TMEKEQALAD----------------------LNSVERSLSDLFRRYENLKGVL------ 702
+EKE+ L L E SL D + ++ +L
Sbjct: 455 NLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKN 514
Query: 703 ------------EGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQ 750
+G KN + + D ++ +E ++ LK EEK+ E +
Sbjct: 515 MMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDE 574
Query: 751 VRTKAKAE---SAALHAG---LRKEQMKVESLERALQQ-KNQEIEELTKICDELIAKL 801
+ K K+E S+ L L+K +E +ER + + ++++ ELT D I +L
Sbjct: 575 LIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKEL 632
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 51.2 bits (121), Expect = 4e-06
Identities = 58/210 (27%), Positives = 96/210 (45%), Gaps = 26/210 (12%)
Query: 608 TLIREEIITKEIEANEWKKKYEE----TRQEVL-------EMRKIVAEYEKTIAQMIEDE 656
TL R IT+E W+ +E +R EV+ + K + + ED+
Sbjct: 188 TLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKELIALQEDK 247
Query: 657 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA 716
T+++S +++ EK + + L+ VERSLS+ +LK + E + +E L++ A
Sbjct: 248 HNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNE---RTQEELRELA 304
Query: 717 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESL 776
Y V + + LK+ AE K EEI Q K +AE L + + + K + L
Sbjct: 305 NKYNGAVNEIKDLSDKLKV-AEGK----QEEIQQ---KGQAEKKELQHKIDEMEEKEQEL 356
Query: 777 E---RALQQKNQ-EIEELTKICDELIAKLG 802
+ ALQ N E LT + + L++K G
Sbjct: 357 QAKIEALQADNDFTNERLTALQEHLLSKSG 386
Score = 36.2 bits (82), Expect = 0.12
Identities = 40/202 (19%), Positives = 85/202 (42%), Gaps = 20/202 (9%)
Query: 601 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTS 660
S++ + ++EE+ E W+K E +E+ ++ + Q ED+QR
Sbjct: 579 SERDTDIASLQEELKKVRAELERWRKAASEYEKEITSLQNSF----QLRCQQCEDQQREE 634
Query: 661 MTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKK-----NEEALKKC 715
T +L E E+ + N++E L R L L+ +K +++L+
Sbjct: 635 AT------RLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLELT 688
Query: 716 AQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVES 775
+ + ++ ++E Q + + D A ++ + +KA+ ++ + K Q +
Sbjct: 689 SDLSILQMSRKELENQVGSLKEQHLRDSA--DLKTLLSKAENQAKDVQKEYEKTQTVLSE 746
Query: 776 LERALQQKNQEIEELTKICDEL 797
L+ + QE + +T DEL
Sbjct: 747 LKLKFEMTEQEKQSIT---DEL 765
Score = 32.7 bits (73), Expect = 1.4
Identities = 31/141 (21%), Positives = 55/141 (39%), Gaps = 7/141 (4%)
Query: 607 LTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKS 666
L +R+E E E + K++ E+ K + +K ++ D M+ ++
Sbjct: 642 LEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKEL 701
Query: 667 FQQLTMEKEQALAD-------LNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDY 719
Q+ KEQ L D L+ E D+ + YE + VL K E ++ Q
Sbjct: 702 ENQVGSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSI 761
Query: 720 LARVKQEEQRYQALKIHAEEK 740
+KQ + + L+ K
Sbjct: 762 TDELKQCKNNLKLLREKGNNK 782
Score = 32.3 bits (72), Expect = 1.8
Identities = 38/204 (18%), Positives = 86/204 (42%), Gaps = 26/204 (12%)
Query: 607 LTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKS 666
LT ++E +++K + ++ E +++++ + E+T + E +T
Sbjct: 374 LTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEET---KLSKENQTRAKESDF 430
Query: 667 FQQLTMEKEQALADLNSV---ERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARV 723
L+ KE++ D E+ L++ + LK L+G + EA
Sbjct: 431 SDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEA------------ 478
Query: 724 KQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQ- 782
KQE Q + I A+E + ++ +++ + E A + + +++ L+ LQ+
Sbjct: 479 KQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRL 538
Query: 783 -------KNQEIEELTKICDELIA 799
+ ++ E+T DEL++
Sbjct: 539 HIDTENLREEKDSEITSTRDELLS 562
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 50.8 bits (120), Expect = 5e-06
Identities = 54/226 (23%), Positives = 107/226 (47%), Gaps = 30/226 (13%)
Query: 594 DGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQM- 652
D CL D+ A L ++ ++ A E K + QE+ +R +YE+ +
Sbjct: 1496 DRKCLE--DENARLQRVQYDLQKANSSATETINKLKVQEQELTRLR---IDYERVSQERT 1550
Query: 653 IEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKN--EE 710
++D+ T Q S ++L ++K++ +LN ++R+ S+ + + L+ LEG +++ E+
Sbjct: 1551 VKDQDITRF--QNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ 1608
Query: 711 ALK------KCAQDYLARVKQEE---QRYQALKIHAEEKLDKANEEIAQVRTKAKA---- 757
A+K + Q + + + E+ Q+ L H EK + EE+ ++ ++ +A
Sbjct: 1609 AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREK-QRTQEELRRLSSEVEALRRQ 1667
Query: 758 ----ESAALHAGLRKE--QMKVESLERALQQKNQEIEELTKICDEL 797
+ + A LR E Q +E R+L + EIE L + + L
Sbjct: 1668 LLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENL 1713
Score = 46.2 bits (108), Expect = 1e-04
Identities = 40/182 (21%), Positives = 85/182 (46%), Gaps = 16/182 (8%)
Query: 617 KEIEA--NEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEK 674
KEIE E++++ + + E+ K+ Y++ I + + ++ + QLTM+K
Sbjct: 1325 KEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQK 1384
Query: 675 EQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALK 734
E+ D + + +L R +L E K+ + L + ++ L RV+++ Q+ +A
Sbjct: 1385 EE---DTSGYRAQIDNLTRENRSLS---EEIKRLKNTLTQTTEN-LRRVEEDIQQQKATG 1437
Query: 735 IHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKIC 794
++ + E+ QV ES + + ++ + +Q KN+EIE L ++
Sbjct: 1438 SEVSQRKQQLEVELRQVTQMRTEESV-------RYKQSLDDAAKTIQDKNKEIERLKQLI 1490
Query: 795 DE 796
D+
Sbjct: 1491 DK 1492
Score = 35.8 bits (81), Expect = 0.16
Identities = 34/166 (20%), Positives = 73/166 (43%), Gaps = 20/166 (12%)
Query: 625 KKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSV 684
K++YE E+ K+ Y + ++ + + ++ + ++++M+KE D ++
Sbjct: 1185 KREYEN------ELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKED---DSKNL 1235
Query: 685 ERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKA 744
L L R +LK E + N+ L+ A + R ++ + +A +K
Sbjct: 1236 RNQLDRLSRENRDLKD--EIVRLNDSILQ--ATEQRRRAEENALQQKACGSEIMQKKQHL 1291
Query: 745 NEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 790
E+ QV + ++A + + +E + +Q KN+EIE L
Sbjct: 1292 EIELKQVMQQRSEDNA-------RHKQSLEEAAKTIQDKNKEIERL 1330
Score = 33.5 bits (75), Expect = 0.81
Identities = 42/191 (21%), Positives = 79/191 (41%), Gaps = 21/191 (10%)
Query: 610 IREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQ 669
+ EE+ + A+E K ++ +E+ MR+ + E I + + ++ S+ ++S
Sbjct: 1573 VEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDD 1632
Query: 670 LTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQR 729
L +++ L +R+ +L R EAL++ VKQ R
Sbjct: 1633 LRQQRDVLDGHLREKQRTQEELRR-----------LSSEVEALRRQLLQEQESVKQAHLR 1681
Query: 730 YQALKIHAEEKLDKANE---EIAQVRTKAK---AESAALHAGLRKEQMKVESLER----A 779
+ + E+K NE EI ++++ + E L LR +++ + L R A
Sbjct: 1682 NEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEA 1741
Query: 780 LQQKNQEIEEL 790
KN I EL
Sbjct: 1742 DSDKNATILEL 1752
Score = 33.5 bits (75), Expect = 0.81
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 22/170 (12%)
Query: 637 EMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYE 696
E+R + EY+ E + + T + QL + + L ++ ++DL R E
Sbjct: 1723 ELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTL----ELQGLINDLQRERE 1778
Query: 697 NLKGVLEGFKKN--------EEALKKCAQ------DYLARVKQEEQRYQALKIHAEEKLD 742
NL+ +E F+K +E+ +C Q L ++K EQ L+ E++L+
Sbjct: 1779 NLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQ-RLEDELN 1837
Query: 743 KAN---EEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEE 789
+A E +V+ + + E + L + + + E A+++ E E+
Sbjct: 1838 RAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREK 1887
Score = 33.5 bits (75), Expect = 0.81
Identities = 42/194 (21%), Positives = 86/194 (44%), Gaps = 44/194 (22%)
Query: 610 IREEIITKEIEANEWKKKYEETR---------QEVLEMRKIVAEYEKTIAQMIEDE---- 656
+R+EI + +A E + +E++ +E L ++ V E +K Q +EDE
Sbjct: 1780 LRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRA 1839
Query: 657 QRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCA 716
+ T + Q+L EK+Q DLN + + + EEA++K
Sbjct: 1840 KSTLEAETRVKQRLECEKQQIQNDLNQWKTQ-----------------YSRKEEAIRK-- 1880
Query: 717 QDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESL 776
++ E ++ + K ++++ EI ++ + + + L R+ Q ++E+
Sbjct: 1881 ------IESEREKSEREKNSLRSEIERLQAEIKRIEERCRRK---LEDSTRETQSQLET- 1930
Query: 777 ERALQQKNQEIEEL 790
ER+ Q+ EI++L
Sbjct: 1931 ERSRYQR--EIDKL 1942
Score = 30.4 bits (67), Expect = 6.8
Identities = 34/166 (20%), Positives = 75/166 (45%), Gaps = 8/166 (4%)
Query: 626 KKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADL-NSV 684
+K + +E L +K+ E EK I + + +R + Q+ + E E LA + N
Sbjct: 1143 QKARQCEKENLGWQKL--ESEKAIKEKEYEIERLRVLLQEEGTR-KREYENELAKVRNHY 1199
Query: 685 ERSLSDLFRRYEN----LKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEK 740
+S+L +YE K ++ +E K ++ L R+ +E + + + +
Sbjct: 1200 NEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDS 1259
Query: 741 LDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQE 786
+ +A E+ + A + A ++K+Q L++ +QQ++++
Sbjct: 1260 ILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSED 1305
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 50.1 bits (118), Expect = 8e-06
Identities = 51/187 (27%), Positives = 87/187 (46%), Gaps = 15/187 (8%)
Query: 615 ITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEK 674
+ + ++ E K Y E + + E+ I + YE+ Q I+D ++ + +E+
Sbjct: 684 LQERLKNQEKKIDYFERAKRLEEIPLIKSAYEE---QRIKDMDLWEQQEEERITTMQLER 740
Query: 675 EQALADLNSVERSLSDLFRRYENLKGVL-----EGFKKNEEALKKCAQDYLA---RVKQE 726
E+AL N + R L D LK E K+ EE L + + L R ++E
Sbjct: 741 EKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKE 800
Query: 727 EQRYQALKIHAEEKLDKANEEIAQVRT-KAKAESAALHAGLRKEQMKV---ESLERALQQ 782
E+R + EE+ +A E++ + R + +AE A LR+ Q +V E +ER +Q
Sbjct: 801 ERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQ 860
Query: 783 KNQEIEE 789
+ EIEE
Sbjct: 861 RELEIEE 867
Score = 39.3 bits (90), Expect = 0.015
Identities = 50/219 (22%), Positives = 96/219 (43%), Gaps = 41/219 (18%)
Query: 611 REEIITKEIEANEWKKKYEET-RQEVLEMRK--IVAEYE----KTIAQMIEDEQRTSMTS 663
+EE+ +E E + +K EE RQE E K I+ E+E KT+ + +E ++T + +
Sbjct: 591 KEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGA 650
Query: 664 Q--------------------KSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGV-L 702
+ K +QL EK++ L + E+ + D F R + L+ + L
Sbjct: 651 KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKI-DYFERAKRLEEIPL 709
Query: 703 EGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKAN--------EEIAQVRTK 754
E+ +K D +QEE+R +++ E+ L+ N ++ +R K
Sbjct: 710 IKSAYEEQRIK----DMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLK 765
Query: 755 AKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKI 793
A +S + E+ E L+++ ++ +E +I
Sbjct: 766 AARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRI 804
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 50.1 bits (118), Expect = 8e-06
Identities = 58/250 (23%), Positives = 113/250 (45%), Gaps = 22/250 (8%)
Query: 546 HAFSSSEAGIEKETCQKME-----EDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSE 600
HA S +E G + + Q+++ E L + + S+ VS S ++ L+ IC +
Sbjct: 1197 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKS---KANLEKICRTL 1253
Query: 601 SDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTS 660
D+ + EEI E K + + E E+ + + E E ++Q+ +Q +
Sbjct: 1254 EDQLSEARGKNEEIQRSLSELTTQKSRLQT---EAGELSRQLEEKESIVSQLSRSKQAFT 1310
Query: 661 MTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYL 720
+++ +QL E + A ++++ S D E + EG + + AL K +
Sbjct: 1311 QQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSE-- 1368
Query: 721 ARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERAL 780
V Q +Y+ I E+L++A +++AQ ++ + A++A K SLE+
Sbjct: 1369 --VAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNA-------KCASLEKTK 1419
Query: 781 QQKNQEIEEL 790
Q+ E+E+L
Sbjct: 1420 QRLQGEVEDL 1429
Score = 40.8 bits (94), Expect = 0.005
Identities = 87/416 (20%), Positives = 159/416 (38%), Gaps = 70/416 (16%)
Query: 450 EILESPKKAKSRLITSGCKVKKHETQSLALDACS-RDEGAVISQISDISNRDGHATDEEK 508
E+ E+ KK RL S +V+ + +L+ R +G V + D+ + A +K
Sbjct: 1386 ELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDK 1445
Query: 509 LA----------STSCGQKSAGAEVKGEPEEDL--EYFECSNVPVSTINH--AFSSSEAG 554
T C + A E + L E F+ N ++
Sbjct: 1446 KQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKN 1505
Query: 555 IEKETC---QKMEEDGSTVLGLLES----SAEKAPVSVSCG-GESPLDG----ICLSESD 602
+E+E +++ E+G T+ L +S EKA + ++ E+ L+ I + +
Sbjct: 1506 LEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLE 1565
Query: 603 KTAVLTLIREEIITKEIEANEWKKKYEETRQ--------EVLEMRKIVAEYEKTIAQMIE 654
T V + I +I K+ E + K+ Y+ T + EV + + +K + E
Sbjct: 1566 LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNE 1625
Query: 655 DEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKK 714
E + S ++++ + L L + L D R E+LK L ++ L+
Sbjct: 1626 IEIQLSHANRQAAETLK-HLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQA 1684
Query: 715 CAQDYLARVKQEE--------------QRYQALK------IHAEEKLDK----------- 743
++ A ++Q E +R Q L IH ++KL+
Sbjct: 1685 EVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVED 1744
Query: 744 ANEEIAQVRTKAK---AESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDE 796
A+ + KAK ++A + L+KEQ LER + Q +++L DE
Sbjct: 1745 ASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1800
Score = 40.4 bits (93), Expect = 0.007
Identities = 78/363 (21%), Positives = 148/363 (40%), Gaps = 63/363 (17%)
Query: 491 SQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHA--- 547
++I +++ R A DEE++ + +K + E ++D++ E + V HA
Sbjct: 918 AKIKEVTER---AEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 974
Query: 548 --------FSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLS 599
S + I K T +K + L + AE+ V+ +S L+
Sbjct: 975 KVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLE----- 1029
Query: 600 ESDKTAVLTLIREEIITKEIEANEWKKKYE-----------ETRQEVLEMRKIVAEYEKT 648
+ + +L +E+ + ++E N+ K + + E ++ L+ R ++E
Sbjct: 1030 QQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYC 1089
Query: 649 IAQM-IEDEQRTSMTSQKSFQQL---------TMEKEQALADLNSVERS-----LSDLFR 693
Q +EDEQ + QK ++L +E E+A +RS L +L
Sbjct: 1090 QLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSE 1149
Query: 694 RYENLKGV----LEGFKKNEEALKKCAQDYLARVKQEEQRYQAL-KIHAEE--KLDKANE 746
R E GV +E KK E K +D Q E AL K HA+ +L + +
Sbjct: 1150 RLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQID 1209
Query: 747 EIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKIC----DELIAKLG 802
+ +V+ K + E + +++++ L +++ ++ L KIC D+L G
Sbjct: 1210 NLQRVKQKLEKEKSEF-------KLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARG 1262
Query: 803 KTD 805
K +
Sbjct: 1263 KNE 1265
Score = 37.7 bits (86), Expect = 0.043
Identities = 51/215 (23%), Positives = 96/215 (44%), Gaps = 29/215 (13%)
Query: 610 IREEIITKEIEANEWKKKYEETRQ--EVLEMRKIVAEYE----KTIAQMIEDEQRTSMTS 663
++E++ E AN + + EE R E E + +AE E Q++ + + + +
Sbjct: 1668 LKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHT 1727
Query: 664 QKSFQ----QLTMEKEQALADLNSVE----RSLSDLFRRYENLK------GVLEGFKKNE 709
+K + QL E E A D + E ++++D E LK LE KKN
Sbjct: 1728 KKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN- 1786
Query: 710 EALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAE---SAALHAGL 766
L++ +D R+ + EQ ALK ++++ K I ++ + + E + GL
Sbjct: 1787 --LEQTVKDLQHRLDEAEQL--ALK-GGKKQIQKLETRIRELEFELEGEQKKNTESVKGL 1841
Query: 767 RKEQMKVESLERALQQKNQEIEELTKICDELIAKL 801
RK + +V+ L ++ + + L + D+L K+
Sbjct: 1842 RKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKV 1876
>gi|23503243 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 8 [Homo sapiens]
Length = 392
Score = 50.1 bits (118), Expect = 8e-06
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 36/198 (18%)
Query: 603 KTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMT 662
+T L I +++ + EIE W++KY +E +IV +K +E E+
Sbjct: 173 QTEKLQSIEKQLESNEIEIRFWEQKYNSNLEE-----EIVRLEQKIKRNDVEIEEEEFWE 227
Query: 663 SQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLAR 722
++ +Q E E+ L D L+ + + + E LK DYLA+
Sbjct: 228 NELQIEQ---ENEKQLKD----------------QLQEIRQKITECENKLK----DYLAQ 264
Query: 723 VKQEEQRYQALKIHAEEKLDKANEEIAQVRT-KAKAE-------SAALHAGLRKEQMKVE 774
++ E +A K+ E + + NEE + + K K E S L G++ + +
Sbjct: 265 IRTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLG 324
Query: 775 SLERALQQKNQEIEELTK 792
+ LQ K QE+E+LTK
Sbjct: 325 QATKRLQDKEQELEQLTK 342
>gi|225579095 S-phase cyclin A-associated protein in the ER isoform
b [Homo sapiens]
Length = 1154
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/189 (20%), Positives = 93/189 (49%), Gaps = 12/189 (6%)
Query: 608 TLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEK------TIAQMIEDEQRTSM 661
TL ++++ +E + +WK++ + R+ ++E + + AE+++ + + E+E + +
Sbjct: 320 TLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLHAEFKREVQLQAIVKKAQEEEAKVNE 379
Query: 662 TSQKSFQQLTMEKEQALADLNSVERSLSDL----FRRYENLKGVLEGFKKNEEALKKCAQ 717
+ + + ++ L+ L E+ L++L RR E + E ++ + AL+ Q
Sbjct: 380 IAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQRRQEEKQARDEAVQERKRALEAERQ 439
Query: 718 DYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLE 777
+ + + + +A ++ +KA E+ A+ R + + E A ++E M E L+
Sbjct: 440 ARVEELLMKRKEQEARIEQQRQEKEKAREDAARERARDREERLAALTAAQQEAM--EELQ 497
Query: 778 RALQQKNQE 786
+ +Q K+ E
Sbjct: 498 KKIQLKHDE 506
Score = 31.2 bits (69), Expect = 4.0
Identities = 34/151 (22%), Positives = 63/151 (41%), Gaps = 23/151 (15%)
Query: 629 EETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSL 688
+ R +VL K EYE+ + ++ E+ QR Q + + K A+ + L
Sbjct: 389 QNKRHDVLSKLK---EYEQRLNELQEERQRRQEEKQARDEAVQERKRALEAERQARVEEL 445
Query: 689 SDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKAN--- 745
L +R E + + ++ E+A + A++ R + E+R AL +E +++
Sbjct: 446 --LMKRKEQEARIEQQRQEKEKAREDAARE---RARDREERLAALTAAQQEAMEELQKKI 500
Query: 746 ------------EEIAQVRTKAKAESAALHA 764
E+I Q + KA S+ HA
Sbjct: 501 QLKHDESIRRHMEQIEQRKEKAAELSSGRHA 531
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 49.7 bits (117), Expect = 1e-05
Identities = 64/295 (21%), Positives = 121/295 (41%), Gaps = 13/295 (4%)
Query: 515 GQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKE--TCQKMEEDGSTVLG 572
G+ G + E E L+ + VS + S + KE + + D +L
Sbjct: 1291 GRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQ 1350
Query: 573 LLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETR 632
E+ A+ A S E+ G+ ++ A E+ T + + +EW+++ EE
Sbjct: 1351 E-ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA 1409
Query: 633 QEVL---EMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLS 689
+ E R+ A + + Q + ++ T ++ ++L E + A DL + +S
Sbjct: 1410 GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVS 1469
Query: 690 DLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKI-HAEEKLDKANEEI 748
L ++ +L ++ L+ + A + E+ +AL + A E+ +A EE+
Sbjct: 1470 TLEKKQRKFDQLLA--EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1527
Query: 749 AQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL----TKICDELIA 799
+ +AE AL + V LERA + Q +L T++ DEL A
Sbjct: 1528 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTA 1582
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 37/214 (17%)
Query: 623 EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTME--------K 674
E+ + E ++V + K+ +YE TIA M ED R ++ ++L +
Sbjct: 1035 EFSSQAAEEEEKVKSLNKLRLKYEATIADM-EDRLRKEEKGRQELEKLKRRLDGESSELQ 1093
Query: 675 EQALADLNSVERSLSDLFRRYENLKG--------------VLEGFKKNEEALKKCAQDY- 719
EQ + E + L R+ E L+ +L+ ++ + AL + +D
Sbjct: 1094 EQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLE 1153
Query: 720 ---LARVKQEEQR------YQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQ 770
+AR K E+QR +AL+ E+ LD N + ++R+K + E L L +E
Sbjct: 1154 SERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQ-QELRSKREQEVTELKKTLEEET 1212
Query: 771 MKVESLERALQQKN-QEIEELTKICDELIAKLGK 803
E+ + L+Q++ Q + EL + ++ A+ GK
Sbjct: 1213 RIHEAAVQELRQRHGQALGELAEQLEQ--ARRGK 1244
Score = 35.8 bits (81), Expect = 0.16
Identities = 76/377 (20%), Positives = 144/377 (38%), Gaps = 42/377 (11%)
Query: 449 NEILESPKKAKSRLITSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGHAT---- 504
+E+ E + + R ++ + E + A A + DEG +Q+ S R+ A
Sbjct: 1090 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLK-SLREAQAALAEA 1148
Query: 505 ----DEEKLASTSCGQ--KSAGAEV---KGEPEEDLEYFECSNVPVSTINHAFSSSEAGI 555
+ E++A T + + G E+ +GE E+ L+ S + + +
Sbjct: 1149 QEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTL 1208
Query: 556 EKET------CQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTL 609
E+ET Q++ + LG L E+A G+ + L+ + + L
Sbjct: 1209 EEETRIHEAAVQELRQRHGQALGELAEQLEQAR-----RGKGAWEKTRLALEAEVSELRA 1263
Query: 610 IREEIITKEIEANEWKKKYEETRQEVL---------------EMRKIVAEYEKTIAQMIE 654
+ T E + +++ E QEV ++++ AE E + E
Sbjct: 1264 ELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1323
Query: 655 DEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKK 714
E +T S K + A L R+ L R ++ G ++ E +
Sbjct: 1324 AESKTIRLS-KELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE-EA 1381
Query: 715 CAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVE 774
A++ R Q Q + +E+ A E + R +A E+ AL L ++ V+
Sbjct: 1382 AARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD 1441
Query: 775 SLERALQQKNQEIEELT 791
LER ++ QE+++ T
Sbjct: 1442 RLERGRRRLQQELDDAT 1458
Score = 35.8 bits (81), Expect = 0.16
Identities = 40/168 (23%), Positives = 74/168 (44%), Gaps = 33/168 (19%)
Query: 664 QKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDY---- 719
++ ++ +E+A +L + + LS+ RR E G LE EEA ++ A++
Sbjct: 1374 REQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEA---GEEARRRAAREAEALT 1430
Query: 720 --LARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTK---------------AKAESAAL 762
LA + R + + +++LD A ++ Q R A+ ++A L
Sbjct: 1431 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1490
Query: 763 HAGLRKEQMKVE---------SLERALQQKNQEIEELTKICDELIAKL 801
A +E+ + E SL RAL+++ + EEL + L A+L
Sbjct: 1491 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1538
Score = 34.7 bits (78), Expect = 0.36
Identities = 41/159 (25%), Positives = 83/159 (52%), Gaps = 14/159 (8%)
Query: 637 EMRKIVAEYEKT--IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRR 694
++ K V E E+ +A+ ++ R +T + +LT ++ L +E ++ L +
Sbjct: 1547 DVGKSVHELERACRVAEQAANDLRAQVTELED--ELTAAEDAKLR----LEVTVQALKTQ 1600
Query: 695 YE-NLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQ-ALKIHAEEKLDKANEEI-AQV 751
+E +L+G E ++ L K +D A V+++E+R Q L + A +KL+ EE+ AQ+
Sbjct: 1601 HERDLQGRDEAGEERRRQLAKQLRD--AEVERDEERKQRTLAVAARKKLEGELEELKAQM 1658
Query: 752 RTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 790
+ + + A+ LRK Q +++ L R +++ EE+
Sbjct: 1659 ASAGQGKEEAVKQ-LRKMQAQMKELWREVEETRTSREEI 1696
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 49.7 bits (117), Expect = 1e-05
Identities = 64/295 (21%), Positives = 121/295 (41%), Gaps = 13/295 (4%)
Query: 515 GQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKE--TCQKMEEDGSTVLG 572
G+ G + E E L+ + VS + S + KE + + D +L
Sbjct: 1283 GRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQ 1342
Query: 573 LLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETR 632
E+ A+ A S E+ G+ ++ A E+ T + + +EW+++ EE
Sbjct: 1343 E-ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA 1401
Query: 633 QEVL---EMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLS 689
+ E R+ A + + Q + ++ T ++ ++L E + A DL + +S
Sbjct: 1402 GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVS 1461
Query: 690 DLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKI-HAEEKLDKANEEI 748
L ++ +L ++ L+ + A + E+ +AL + A E+ +A EE+
Sbjct: 1462 TLEKKQRKFDQLLA--EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1519
Query: 749 AQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL----TKICDELIA 799
+ +AE AL + V LERA + Q +L T++ DEL A
Sbjct: 1520 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTA 1574
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/214 (24%), Positives = 96/214 (44%), Gaps = 37/214 (17%)
Query: 623 EWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTME--------K 674
E+ + E ++V + K+ +YE TIA M ED R ++ ++L +
Sbjct: 1027 EFSSQAAEEEEKVKSLNKLRLKYEATIADM-EDRLRKEEKGRQELEKLKRRLDGESSELQ 1085
Query: 675 EQALADLNSVERSLSDLFRRYENLKG--------------VLEGFKKNEEALKKCAQDY- 719
EQ + E + L R+ E L+ +L+ ++ + AL + +D
Sbjct: 1086 EQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLE 1145
Query: 720 ---LARVKQEEQR------YQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQ 770
+AR K E+QR +AL+ E+ LD N + ++R+K + E L L +E
Sbjct: 1146 SERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQ-QELRSKREQEVTELKKTLEEET 1204
Query: 771 MKVESLERALQQKN-QEIEELTKICDELIAKLGK 803
E+ + L+Q++ Q + EL + ++ A+ GK
Sbjct: 1205 RIHEAAVQELRQRHGQALGELAEQLEQ--ARRGK 1236
Score = 35.8 bits (81), Expect = 0.16
Identities = 76/377 (20%), Positives = 144/377 (38%), Gaps = 42/377 (11%)
Query: 449 NEILESPKKAKSRLITSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGHAT---- 504
+E+ E + + R ++ + E + A A + DEG +Q+ S R+ A
Sbjct: 1082 SELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLK-SLREAQAALAEA 1140
Query: 505 ----DEEKLASTSCGQ--KSAGAEV---KGEPEEDLEYFECSNVPVSTINHAFSSSEAGI 555
+ E++A T + + G E+ +GE E+ L+ S + + +
Sbjct: 1141 QEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTL 1200
Query: 556 EKET------CQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTL 609
E+ET Q++ + LG L E+A G+ + L+ + + L
Sbjct: 1201 EEETRIHEAAVQELRQRHGQALGELAEQLEQAR-----RGKGAWEKTRLALEAEVSELRA 1255
Query: 610 IREEIITKEIEANEWKKKYEETRQEVL---------------EMRKIVAEYEKTIAQMIE 654
+ T E + +++ E QEV ++++ AE E + E
Sbjct: 1256 ELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1315
Query: 655 DEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKK 714
E +T S K + A L R+ L R ++ G ++ E +
Sbjct: 1316 AESKTIRLS-KELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE-EA 1373
Query: 715 CAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVE 774
A++ R Q Q + +E+ A E + R +A E+ AL L ++ V+
Sbjct: 1374 AARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD 1433
Query: 775 SLERALQQKNQEIEELT 791
LER ++ QE+++ T
Sbjct: 1434 RLERGRRRLQQELDDAT 1450
Score = 35.8 bits (81), Expect = 0.16
Identities = 40/168 (23%), Positives = 74/168 (44%), Gaps = 33/168 (19%)
Query: 664 QKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDY---- 719
++ ++ +E+A +L + + LS+ RR E G LE EEA ++ A++
Sbjct: 1366 REQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEA---GEEARRRAAREAEALT 1422
Query: 720 --LARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTK---------------AKAESAAL 762
LA + R + + +++LD A ++ Q R A+ ++A L
Sbjct: 1423 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1482
Query: 763 HAGLRKEQMKVE---------SLERALQQKNQEIEELTKICDELIAKL 801
A +E+ + E SL RAL+++ + EEL + L A+L
Sbjct: 1483 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1530
Score = 34.7 bits (78), Expect = 0.36
Identities = 41/159 (25%), Positives = 83/159 (52%), Gaps = 14/159 (8%)
Query: 637 EMRKIVAEYEKT--IAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRR 694
++ K V E E+ +A+ ++ R +T + +LT ++ L +E ++ L +
Sbjct: 1539 DVGKSVHELERACRVAEQAANDLRAQVTELED--ELTAAEDAKLR----LEVTVQALKTQ 1592
Query: 695 YE-NLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQ-ALKIHAEEKLDKANEEI-AQV 751
+E +L+G E ++ L K +D A V+++E+R Q L + A +KL+ EE+ AQ+
Sbjct: 1593 HERDLQGRDEAGEERRRQLAKQLRD--AEVERDEERKQRTLAVAARKKLEGELEELKAQM 1650
Query: 752 RTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEEL 790
+ + + A+ LRK Q +++ L R +++ EE+
Sbjct: 1651 ASAGQGKEEAVKQ-LRKMQAQMKELWREVEETRTSREEI 1688
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.124 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,056,501
Number of Sequences: 37866
Number of extensions: 1695419
Number of successful extensions: 8227
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 724
Number of HSP's that attempted gapping in prelim test: 6246
Number of HSP's gapped (non-prelim): 2308
length of query: 805
length of database: 18,247,518
effective HSP length: 110
effective length of query: 695
effective length of database: 14,082,258
effective search space: 9787169310
effective search space used: 9787169310
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.