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Search of human proteins with 169234949
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169234949 CWF19-like 2, cell cycle control [Homo sapiens]
(894 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169234949 CWF19-like 2, cell cycle control [Homo sapiens] 1800 0.0
gi|93352551 CWF19-like 1, cell cycle control [Homo sapiens] 91 5e-18
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 70 7e-12
gi|148746195 trichohyalin [Homo sapiens] 70 1e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 62 2e-09
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 62 2e-09
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 59 3e-08
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 58 3e-08
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 58 3e-08
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 58 3e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 57 6e-08
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 57 8e-08
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 57 8e-08
gi|87299628 biorientation of chromosomes in cell division 1-like... 57 8e-08
gi|42718020 retinitis pigmentosa 9 [Homo sapiens] 57 8e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 57 1e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 57 1e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 56 1e-07
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 56 1e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 56 2e-07
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 55 2e-07
gi|31982906 cingulin-like 1 [Homo sapiens] 55 2e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 55 4e-07
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 55 4e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 54 5e-07
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 54 6e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 54 6e-07
gi|168229156 NFKB activating protein [Homo sapiens] 54 8e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 54 8e-07
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 53 1e-06
>gi|169234949 CWF19-like 2, cell cycle control [Homo sapiens]
Length = 894
Score = 1800 bits (4662), Expect = 0.0
Identities = 894/894 (100%), Positives = 894/894 (100%)
Query: 1 MATSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWML 60
MATSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWML
Sbjct: 1 MATSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWML 60
Query: 61 PDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV 120
PDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV
Sbjct: 61 PDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV 120
Query: 121 EAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKI 180
EAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKI
Sbjct: 121 EAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKI 180
Query: 181 EQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRM 240
EQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRM
Sbjct: 181 EQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRM 240
Query: 241 KEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQ 300
KEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQ
Sbjct: 241 KEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQ 300
Query: 301 ESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFS 360
ESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFS
Sbjct: 301 ESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFS 360
Query: 361 FGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWS 420
FGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWS
Sbjct: 361 FGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWS 420
Query: 421 RSDGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSP 480
RSDGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSP
Sbjct: 421 RSDGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSP 480
Query: 481 ERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVEN 540
ERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVEN
Sbjct: 481 ERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVEN 540
Query: 541 EDQQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLN 600
EDQQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLN
Sbjct: 541 EDQQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLN 600
Query: 601 DLVKNEKMGTAENQNKLFMRMASKFMGKTDGDYYTLDDMFVSKAAERERLGEEEENQRKK 660
DLVKNEKMGTAENQNKLFMRMASKFMGKTDGDYYTLDDMFVSKAAERERLGEEEENQRKK
Sbjct: 601 DLVKNEKMGTAENQNKLFMRMASKFMGKTDGDYYTLDDMFVSKAAERERLGEEEENQRKK 660
Query: 661 AIAEHRSLAAQMEKCLYCFDSSQFPKHLIVAIGVKVYLCLPNVRSLTEGHCLIVPLQHHR 720
AIAEHRSLAAQMEKCLYCFDSSQFPKHLIVAIGVKVYLCLPNVRSLTEGHCLIVPLQHHR
Sbjct: 661 AIAEHRSLAAQMEKCLYCFDSSQFPKHLIVAIGVKVYLCLPNVRSLTEGHCLIVPLQHHR 720
Query: 721 AATLLDEDIWEEIQMFRKSLVKMFEDKGLDCIFLETNMSMKKQYHMVYECIPLPKEVGDM 780
AATLLDEDIWEEIQMFRKSLVKMFEDKGLDCIFLETNMSMKKQYHMVYECIPLPKEVGDM
Sbjct: 721 AATLLDEDIWEEIQMFRKSLVKMFEDKGLDCIFLETNMSMKKQYHMVYECIPLPKEVGDM 780
Query: 781 APIYFKKAIMESDEEWSMNKKLIDLSSKDIRKSVPRGLPYFSVDFGLHGGFAHVIEDQHK 840
APIYFKKAIMESDEEWSMNKKLIDLSSKDIRKSVPRGLPYFSVDFGLHGGFAHVIEDQHK
Sbjct: 781 APIYFKKAIMESDEEWSMNKKLIDLSSKDIRKSVPRGLPYFSVDFGLHGGFAHVIEDQHK 840
Query: 841 FPHYFGKEIIGGMLDIEPRLWRKGIRESFEDQRKKALQFAQWWKPYDFTKSKNY 894
FPHYFGKEIIGGMLDIEPRLWRKGIRESFEDQRKKALQFAQWWKPYDFTKSKNY
Sbjct: 841 FPHYFGKEIIGGMLDIEPRLWRKGIRESFEDQRKKALQFAQWWKPYDFTKSKNY 894
>gi|93352551 CWF19-like 1, cell cycle control [Homo sapiens]
Length = 538
Score = 90.9 bits (224), Expect = 5e-18
Identities = 61/218 (27%), Positives = 111/218 (50%), Gaps = 13/218 (5%)
Query: 675 CLYCFDSSQFPKHLIVAIGVKVYLCLPNVRSLTEGHCLIVPLQHHRAATLLDEDIWEEIQ 734
C +C S + KHL+V IG YL L L++ H LI+P+ H+++ L ++ EE++
Sbjct: 328 CWFCLASPEVEKHLVVNIGTHCYLALAK-GGLSDDHVLILPIGHYQSVVELSAEVVEEVE 386
Query: 735 MFRKSLVKMFEDKGLDCIFLETNMSMKKQYHMVYECIPLPKEVGDMAPIYFKKAIMESDE 794
++ +L + F+ +G C+ E N K +H+ + IP+P I K A + +
Sbjct: 387 KYKATLRRFFKSRGKWCVVFERNY---KSHHLQLQVIPVPISCSTTDDI--KDAFITQAQ 441
Query: 795 EWSMNKKLIDL-SSKDIRKSVPRGLPYFSVDFGLHGGFAHVIEDQHKFPHYFGKEIIG-- 851
E + +L+++ DI++ G YF V+ H I + FP FG+E++
Sbjct: 442 EQQI--ELLEIPEHSDIKQIAQPGAAYFYVELDTGEKLFHRI--KKNFPLQFGREVLASE 497
Query: 852 GMLDIEPRLWRKGIRESFEDQRKKALQFAQWWKPYDFT 889
+L++ + + + S ED+ A +F + ++PYDFT
Sbjct: 498 AILNVPDKSDWRQCQISKEDEETLARRFRKDFEPYDFT 535
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 70.5 bits (171), Expect = 7e-12
Identities = 117/564 (20%), Positives = 231/564 (40%), Gaps = 78/564 (13%)
Query: 68 EQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQK-----YEKNNESSDSSSSSEDEWVEA 122
E ++E S K+KKK K+S+K KKEKKK+ K +K E N + S+ E +
Sbjct: 220 ESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPP 279
Query: 123 VPSQTPDKEKAWKVKDEKSGKDDTQIIKRD----EWMTVDFMSVKTVSSSSLKAEKETMR 178
+P K+ DEK K+ + +R+ + V+ S K + R
Sbjct: 280 IPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPR 339
Query: 179 KIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLR---- 234
+ + +++ + + E P+W+ ++ + +VS G W++
Sbjct: 340 RY-RTPSRSRSRDRFRRSETPPHWR--------QEMQRAQRMRVS----SGERWIKGDKS 386
Query: 235 ---------KSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRE 285
+S +R+KE+ RN V+E + K++D K+ S + D RR
Sbjct: 387 ELNEIKENQRSPVRVKERKITDHRN----VSESPNRKNEKEKKVKD-HKSNSKERDIRRN 441
Query: 286 RWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKR--PGS 343
+ Y +K + +S+ K + S++R D+ N N EK + R
Sbjct: 442 SEKDDKYKNKVKKRAKSKSRSKSKEKSKSKER----DSKHNRNEEKRMRSRSKGRDHENV 497
Query: 344 LETCRRESNPRQNQEFSFGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCS 403
E ++ + ++QE S ++K L +E HSK ++ + + S + + +
Sbjct: 498 KEKEKQSDSKGKDQERSRSKEKSKQLESKSNEH--DHSKSKEKDRRAQSRS--RECDITK 553
Query: 404 GFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQDEVL-RDD 462
G K + NS R S SR R + ++ + S + H++ ++ R + + R
Sbjct: 554 G--KHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRT 611
Query: 463 PPKKEHLRD--TKSTFAGSPERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQL----- 515
PP + +D + + S ERE + D+ +K + N E +++
Sbjct: 612 PPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESK--SSHRKENSESEKRMYSKSR 669
Query: 516 ------KVQLEKANKFKETITQIPKKSGVENEDQQEVILVRTDQSGRVWPVNTPGKSLES 569
+ +KA++ + ++I K+S +NE + ++ + D+ R S+E
Sbjct: 670 DHNSSNNSREKKADRDQSPFSKI-KQSSQDNELKSSMLKNKEDEKIR--------SSVEK 720
Query: 570 QGGRRKRQMVSTHEERERVRYFHD 593
+ + K Q + H + ++ H+
Sbjct: 721 ENQKSKGQ-ENDHVHEKNKKFDHE 743
Score = 52.0 bits (123), Expect = 2e-06
Identities = 112/592 (18%), Positives = 211/592 (35%), Gaps = 67/592 (11%)
Query: 91 KEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIK 150
K K KK +K++++ ++ SS SSS S+ S + D E A + K +K K + +
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239
Query: 151 RDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLP 210
+ K K++K + E E +A QS + E+ P
Sbjct: 240 KH----------KKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPI--------- 280
Query: 211 PEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLE 270
PE+ + + E + R+ + + ++ R G +
Sbjct: 281 PENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRR 340
Query: 271 DAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNE 330
+ S D R P + + Q Q R S ++ D+ + +N +
Sbjct: 341 YRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERW--IKGDKSELNEIKENQRSP 398
Query: 331 KFIGDEK--DKRPGSLETCRRESNPRQNQEFSFGNLRAKFLRPSDDEELSFHSKGRKFEP 388
+ + K D R S E+ R++ + + N + + +R + +++ + +K +K
Sbjct: 399 VRVKERKITDHRNVS-ESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAK 457
Query: 389 LSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHVPE 448
S S + K +N E+R+ SRS GR H N K E +D E
Sbjct: 458 SKSRSKSKEKSKSKERDSKHNRNEEKRMR--SRSKGR---DHENVKEKEKQSDSKGKDQE 512
Query: 449 DPREKSQDEVLRDDPPKKEHLRD-TKSTFAGSPERESIHILSVDEKNKLGAKIIKAEMMG 507
R K + + L + +H + K A S RE I K +
Sbjct: 513 RSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRE--------------CDITKGKHSY 558
Query: 508 NMELAEQLKVQLEKANKFKETITQIPKKSGVENEDQQEVILVRTDQSGRVWPVNTPGKSL 567
N E+ + + +++ + + + E +E R +S PG+S
Sbjct: 559 NSRTRERSRSR-DRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSR 617
Query: 568 ESQGGRRKRQMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGTAENQNKLFM-------- 619
RR+R S+ E + R + D + + + +E++ +++
Sbjct: 618 SKDRRRRRRDSRSSEREESQSR---NKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSS 674
Query: 620 ---------RMASKF--MGKTDGDYYTLDDMFVSKAAERERLGEEEENQRKK 660
R S F + ++ D M +K E+ R E+ENQ+ K
Sbjct: 675 NNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSK 726
Score = 42.4 bits (98), Expect = 0.002
Identities = 70/354 (19%), Positives = 128/354 (36%), Gaps = 49/354 (13%)
Query: 16 KSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHS 75
+ I E+ + +V ++AK+ + + K + R + R ++H
Sbjct: 436 RDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHE 495
Query: 76 VKKKKKK--DKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKA 133
K+K+K D K ++ + K+ KQ K+NE S S +D +Q+ +E
Sbjct: 496 NVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDR-----RAQSRSRE-- 548
Query: 134 WKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKL 193
D GK R+ S S ++ + R +++++++ E +
Sbjct: 549 ---CDITKGKHSYNSRTRER------------SRSRDRSRRVRSRTHDRDRSRSKEYHRY 593
Query: 194 MERELNPYWKDGG--TGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNF 251
E+E + PP + R+ R E+ E QSRN
Sbjct: 594 REQEYRRRGRSRSRERRTPPGRSRSKDRRR------------RRRDSRSSEREESQSRN- 640
Query: 252 EDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYG 311
++Y + E S + E + S K Y + R + + + + +S K
Sbjct: 641 ----KDKYRNQESKSSHRK--ENSESEKRMYSKSRDHNSSNNSREKKADRD-QSPFSKIK 693
Query: 312 NSSRDRYATTDTAKNSNNEKF---IGDEKDKRPGSLETCRRESNPRQNQEFSFG 362
SS+D + KN +EK + E K G E N + + E S G
Sbjct: 694 QSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPG 747
Score = 35.4 bits (80), Expect = 0.24
Identities = 31/128 (24%), Positives = 56/128 (43%), Gaps = 21/128 (16%)
Query: 11 RFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNER---- 66
R ++S E + Q+RN +++K++ KE + KR+ + N R
Sbjct: 624 RRRDSRSSEREESQSRNKDKYRNQESKSSHRKENS-ESEKRMYSKSRDHNSSNNSREKKA 682
Query: 67 ---------IEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQK-------YEKNNESSD 110
I+Q SQ++ +K K+K +K + +K+++K K +EKN +
Sbjct: 683 DRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDH 742
Query: 111 SSSSSEDE 118
SS DE
Sbjct: 743 ESSPGTDE 750
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 69.7 bits (169), Expect = 1e-11
Identities = 109/597 (18%), Positives = 243/597 (40%), Gaps = 62/597 (10%)
Query: 5 MAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKE---LKRLRGEDTWMLP 61
+A + E + +E+R Q R+ E+ RQ + E+EERR E L+ +G +T P
Sbjct: 148 LAEGEEQSEKQERLEQRDRQRRDE--ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFP 205
Query: 62 DVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVE 121
D EQ + ++ ++K + ++ ++E++ + +++ EK ++ E+E ++
Sbjct: 206 DE----EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261
Query: 122 AVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIE 181
+ P +++ + ++E+ K + Q ++R+ + L+ E++ RK E
Sbjct: 262 ---EEEPQRQRELQEEEEQLRKLERQELRRER-------QEEEQQQQRLRREQQLRRKQE 311
Query: 182 QEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMK 241
+E+ + E+ + + + L E R+ LR +
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQ-----------------EERREQQLRRE 354
Query: 242 EQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQE 301
++ E++ + E ++ + + E+ ++ RRE+ + + Q
Sbjct: 355 QEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR-------REQQL 407
Query: 302 SRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSF 361
RE L + R++ + + + +K + +++R + RR+ R+ +
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Query: 362 GNLRAKFLRPSDDEE------LSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEER 415
R K D EE L + R+ + L + R + EER
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 416 LTSWSRSDGRGDKKHSNQKPSETSTDEHQHVPEDPRE---KSQDEVLRDDPPKKEHLRDT 472
L RS+ + ++ ++ +E + + ++ RE K + E RD K+E R
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ 587
Query: 473 KSTFAGSPERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQI 532
+ ER L +E +L + + + + E E+ + QL K+ + +E Q
Sbjct: 588 QRLKREQEERLE-QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Query: 533 PKKSGVENEDQQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVR 589
++ E ++++E L R ++ R+ + L+ + +R+ EE+E+ R
Sbjct: 647 LRR---EQQERREQRLKREEEEERL------EQRLKREHEEERREQELAEEEQEQAR 694
Score = 64.3 bits (155), Expect = 5e-10
Identities = 129/696 (18%), Positives = 267/696 (38%), Gaps = 95/696 (13%)
Query: 19 EERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKK 78
EE +E R R + RQ E+E + +E ++L+ E+ +L + E+ + +E +K
Sbjct: 908 EEEEELQREEREKRRRQ-----EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK 962
Query: 79 KKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV--EAVPSQTPDKEKAWKV 136
KK + ++ E+ +K ++Q+ EK + E++ + E + + E+ ++
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 137 KDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQE--KNQALEQSKLM 194
KDE +++ + + E + + L+ E+E + E+E + Q LE+
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
Query: 195 ERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDI 254
E EL + P + R +++ E+Q R E++
Sbjct: 1083 EEELQQEEEQLLREEPEK--------------------------RRRQERERQCREEEEL 1116
Query: 255 VAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSS 314
E + L + + +E R+ R + ++ Q +E E K
Sbjct: 1117 QQEE-------EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE----KRRRQE 1165
Query: 315 RDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRAKFLRPSDD 374
+R + E+ + +E++KR E RE Q Q+ R + R D
Sbjct: 1166 LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK------RKQRYRDEDQ 1219
Query: 375 E-ELSFHSKGRKFEPLSSSSALVAQGSLCSGFR---------KPTKNSEERLTSWSRSDG 424
+L + + K E + + +G FR + ++ + L +
Sbjct: 1220 RSDLKWQWEPEK-ENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278
Query: 425 RGDKKHSNQKPSETSTDEHQHVPEDPRE------KSQDE--VLRDDPPKKEHLRDTKSTF 476
R ++ Q+ +E Q E+ +E KSQ+E +LR++ +K ++T F
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF 1338
Query: 477 AGSP----ERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQL-EKANKFKETITQ 531
ERE + + K + ++ + G L E+ +++ E+ KF + Q
Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398
Query: 532 IPKKSGVENEDQQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYF 591
+ + E E Q +R D+ + + E Q R++R EE++ R
Sbjct: 1399 LRCQ---EREQQ-----LRQDRDRKF-------REEEQQLSRQERDRKFREEEQQVRRQE 1443
Query: 592 HDDDNLSLNDLVKNEKMGTAENQNKLFMRMASKFMGKTDGDYYTLDDMFVSKAAERERLG 651
+ L ++ E+ + +L + + + + D L++ + ER+R
Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKF 1503
Query: 652 EEEE----NQRKKAIAEHRSLAAQMEKCLYCFDSSQ 683
E+E +K + E + L Q + + + Q
Sbjct: 1504 REQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ 1539
Score = 58.5 bits (140), Expect = 3e-08
Identities = 129/708 (18%), Positives = 265/708 (37%), Gaps = 73/708 (10%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
E + EER+EQ E R+ + E+EE R+E + R ++ R +Q +
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKS----------KKQKYEKNNESSDSSSSSEDEWVEA 122
E ++++++ + + ++++ ++ ++Q+ + E E E E
Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 123 VPSQTPDKEKAWKVKDEKSG-----------KDDTQIIKRDEWMTVDFMSVKTVSSSSLK 171
+ ++ + W ++E++ K D + +R+ W+ ++ + +
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLE---EEERREQQER 502
Query: 172 AEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLS 231
E++ R+ E+ + Q L++ + ER + E+ + + E+ L
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR---EEEKRLE 559
Query: 232 WLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPT 291
R+ +EQ E++ + + E + + + E E+ +E R E+ +
Sbjct: 560 QERREQRLKREQEERRDQLLKR--EEERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617
Query: 292 YSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRES 351
K + +E R L+K R + E+ + E+++ R
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
Query: 352 NPRQNQEFSFGNLRAKFLRPSDDEELSFHSKGR--KFEPLSSSSALVAQGSLCS------ 403
R+ QE L + E+ K R K++ S A Q + S
Sbjct: 678 EERREQE----------LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE 727
Query: 404 GFRKPTKNSEERLTSWSRSDGRGDKK-HSNQKPSETSTDEHQHVPEDPREKSQDEVLRDD 462
G R+ + E+R S + +++ H Q+ E D + + + + L
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSAR 787
Query: 463 PPKKEHLRDTKSTFAGSPERESIHILSVDEKNKLGAKIIKAEM-MGNMELAEQLKVQLEK 521
PP +E R+ + +RE + +EK + + + E + +E EQL+ + E+
Sbjct: 788 PPLREQ-RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ-RRER 845
Query: 522 ANKFKETITQIPKKSGV-ENEDQQEVILVRTDQSGRVWPVNTPGKSLES--------QGG 572
A + +E ++ G+ E+++++ R DQ R W + K Q
Sbjct: 846 AQQLQE------EEDGLQEDQERRRSQEQRRDQKWR-WQLEEERKRRRHTLYAKPALQEQ 898
Query: 573 RRKRQMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGTAENQNKLFMRMASKFMGKTDGD 632
RK Q + EE E R + + E+ + + +L K +
Sbjct: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER 958
Query: 633 YYTLDDMFVSKAAERERLGEEEE----NQRKKAIAEHRSLAAQMEKCL 676
Y D K E + LGEE E +R+K E L + E+ L
Sbjct: 959 QYRKDKKLQQK--EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Score = 56.2 bits (134), Expect = 1e-07
Identities = 132/714 (18%), Positives = 281/714 (39%), Gaps = 115/714 (16%)
Query: 11 RFESAKSIEERKEQ-TRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQ 69
R + + EER++Q ++ E RQ + E++ERR++ RL+ E+ ER+EQ
Sbjct: 619 RLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ--RLKREEE------EERLEQ 670
Query: 70 -FSQEHSVKKKKKK--DKHSKKAKKEKKKKSKKQKYEKNNESSDSSS------------- 113
+EH ++++++ ++ ++A++ K + K +++ +E+ S
Sbjct: 671 RLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQR 730
Query: 114 ------------SSEDEWVEAVPSQTPDKEK------AWKVKDEKSGKDDTQII------ 149
SE +W E + +E+ W+ + E+ + Q +
Sbjct: 731 RRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL 790
Query: 150 --KRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQAL----EQSKLMERELNPYWK 203
+R+ + + + + EKE R+ +E+ + L E+ +L RE +
Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
Query: 204 DGGTGLPPEDCSVSSITKVSVVEDGGLSW-------LRKSYLRMKEQAEKQSRNFEDIVA 256
+ GL + S + D W R+ L K ++Q R + ++
Sbjct: 851 EEEDGLQEDQERRRSQEQ---RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907
Query: 257 ERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRD 316
E E + + E+ EK +E R+ R + ++ Q +E RE K R+
Sbjct: 908 E-----EEEELQREEREK-RRRQEQERQYREEEQLQQEEEQLLREERE----KRRRQERE 957
Query: 317 RYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRAKFLRPSDDE- 375
R D E+ +G+E +KR R+E + +E + LR ++
Sbjct: 958 RQYRKDKKLQQKEEQLLGEEPEKRR------RQEREKKYREEEELQQEEEQLLREEREKR 1011
Query: 376 -ELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQK 434
+ + RK + L + L R+ + E + + +++ +
Sbjct: 1012 RRQEWERQYRKKDELQQE-----EEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Query: 435 PSETSTD---EHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVD 491
ET E Q+ E+ ++ ++++LR++P K+ + ++ L +
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
Query: 492 EKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENE-DQQEVILVR 550
E+ K + ++ + E+ +Q + QL + K ++ ++ E E Q+E L+R
Sbjct: 1127 EREKRRRQELERQYREEEEV-QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 551 TDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGT 610
+Q R + R+ R+ ++ + RY +D L + EK
Sbjct: 1186 EEQEKR-----------RQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEK-EN 1233
Query: 611 AENQNKLFMRMASKFMGKTDGDYYTLDDMFV----SKAAERERLGEEEENQRKK 660
A NK++ + G+ + + L+D + S+ + LGE++E R++
Sbjct: 1234 AVRDNKVYCK------GRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQ 1281
Score = 52.8 bits (125), Expect = 1e-06
Identities = 94/579 (16%), Positives = 230/579 (39%), Gaps = 75/579 (12%)
Query: 20 ERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKK 79
ER+E R + E +Q + E++ RRK+ + R + ER EQ QE +++
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ-------EERREQ--QERREQQE 332
Query: 80 KKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDE 139
+++++ ++ ++E++++ +++ E+ E+E E + + +++ E
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392
Query: 140 KSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLMERELN 199
+ + + Q ++R++ + + L+ E++ R+ E+E+++ + + E+ L
Sbjct: 393 QQLRREQQ-LRREQQLR---REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448
Query: 200 PYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEK--QSRNFEDIVAE 257
++ R+ +L+ +E+ E+ Q R + + +
Sbjct: 449 REQEE-----------------------------RRDWLKREEETERHEQERRKQQLKRD 479
Query: 258 RYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDR 317
+ KLE+ E+ +++ R ++ R+ + Q + E + ++ S +
Sbjct: 480 QEEERRERWLKLEEEER--REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537
Query: 318 YATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNL-------RAKFLR 370
+ E+ + E++KR LE RRE ++ QE L R + L+
Sbjct: 538 LR---REQEERREQLLKREEEKR---LEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Query: 371 PSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKH 430
+E L K + E L + K + EER +S+ + +++
Sbjct: 592 REQEERLEQRLKREEVERLEQEERREQR-------LKREEPEEERRQQLLKSEEQEERRQ 644
Query: 431 SNQKPSETSTDEHQHVPEDPREKSQDEVLR--DDPPKKEHLRDTKSTFAGSPERESIHIL 488
+ + E + E+ E+ + + R ++ +++ L + + A + I
Sbjct: 645 QQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704
Query: 489 SVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENEDQQEVIL 548
+++ A+ K + ++ + + E+ + +E+ Q ++ + Q+E
Sbjct: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE--- 761
Query: 549 VRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERER 587
+ W KS +G +R E+RER
Sbjct: 762 --EQRRDFTWQWQAEEKS--ERGRQRLSARPPLREQRER 796
Score = 40.0 bits (92), Expect = 0.010
Identities = 55/366 (15%), Positives = 155/366 (42%), Gaps = 29/366 (7%)
Query: 16 KSIEERKEQTRNARAEVLRQAK-ANFEKEER------RKELKRLRGEDTWMLPDVNERIE 68
K ++E ++ R R + RQ + F +EE+ ++L R + + L + R +
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591
Query: 69 QFSQ---EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPS 125
+ + E + ++++ + + ++++K + +Q ++ E + +++E P
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQ 1651
Query: 126 -QTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEK 184
+ ++E+ + ++ +++ Q+++ E + + + E++ +R+ E+E+
Sbjct: 1652 LRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR----RQERDRKFREEEQQLRRQERER 1707
Query: 185 NQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKV----SVVEDGGLSWLRKSYLRM 240
E+ +L +EL +++ ++ + + ++E+ L R+
Sbjct: 1708 KFLQEEQQLRRQELERKFRE--EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
Query: 241 KEQAEKQSRNFEDIVAER----YGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKA 296
+++ +++ R E + ER S E + E+ + +E R + R Y +
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825
Query: 297 QNCQESRESDLVKYGNS----SRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESN 352
+ Q + ++ + +++AT + ++ E + +E+ +R R E
Sbjct: 1826 EQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885
Query: 353 PRQNQE 358
RQ +E
Sbjct: 1886 RRQQKE 1891
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/292 (19%), Positives = 134/292 (45%), Gaps = 32/292 (10%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERI-EQFS 71
E + I+E++E+ R ++ RQ + +EKEE+ + + + E + ++ E++ EQ
Sbjct: 299 EREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 358
Query: 72 QEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKE 131
+K+++++K ++ K+++++ ++ EK E + E+ E +E
Sbjct: 359 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 418
Query: 132 KAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQS 191
K W+ ++E +++ ++R E + +E +KI +++ + EQ
Sbjct: 419 KMWEQEEEMQEQEEK--MRRQE-----------------EKIREQEKKIREQEEKIREQE 459
Query: 192 KLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNF 251
++M+ + + G E K+ E+ +R+ +++EQ EK+ R
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQE-------AKMQEQEEK----MRRQEEKIREQ-EKKIREQ 507
Query: 252 EDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESR 303
E+ + E+ M+ + K+ + E+ +E+ +E+ K ++ QE R
Sbjct: 508 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVR 559
Score = 50.4 bits (119), Expect = 7e-06
Identities = 42/239 (17%), Positives = 105/239 (43%), Gaps = 13/239 (5%)
Query: 13 ESAKSIEERK-EQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFS 71
E + +EE+ EQ + E RQ + ++E+R+E + + + E+I +
Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403
Query: 72 QEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKE 131
+ +++K ++ K ++E++ + +++K + E E E + Q E
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ----E 459
Query: 132 KAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQS 191
+ + ++EK G+ + ++ +++ M ++ + EK KI +++ + EQ
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK----KIREQEEKIREQE 515
Query: 192 KLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRN 250
++M+ + W+ E+ K+ E+ +R+ +R+++Q EK +
Sbjct: 516 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK----MREQEVRLRQQEEKMQEH 570
Score = 45.8 bits (107), Expect = 2e-04
Identities = 60/355 (16%), Positives = 150/355 (42%), Gaps = 14/355 (3%)
Query: 9 SGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIE 68
S + E +++E K + A+ +L Q + E + KEL+ + + + + NE
Sbjct: 223 SEKSEIQLNVKELKRKLERAKL-LLPQQQLQAEADHLGKELQSVSAKLQAQVEE-NELWN 280
Query: 69 QFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTP 128
+ +Q+ K ++++K ++ +K ++++ K ++ E+ + ++E +
Sbjct: 281 RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 340
Query: 129 DKEKAWKVKDEKSGKDD---TQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMR----KIE 181
+KE+ + +EK + + Q KR E + + + + ++E +R KI
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400
Query: 182 QEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMK 241
+++ EQ + M + W+ E+ K+ E +R+ +++
Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE----KKIREQEEKIR 456
Query: 242 EQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQE 301
EQ E+ + E+ + E+ G M ++K+++ E+ +E+ RE+ +K ++ QE
Sbjct: 457 EQ-EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 515
Query: 302 SRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQN 356
+ + ++ + EK E+ R + ++E +++
Sbjct: 516 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 33.9 bits (76), Expect = 0.69
Identities = 68/451 (15%), Positives = 168/451 (37%), Gaps = 68/451 (15%)
Query: 107 ESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVS 166
E+ D S D W A + A + +K+ + ++ K + ++++ T++
Sbjct: 147 EARDLISRLHDSWKFA--GELEQALSAVATQKKKADRYIEELTKERDALSLELYR-NTIT 203
Query: 167 SSSLKAE----KETMRKIEQEKNQALEQSKLMERELN--------PYWKDGGTGLPPEDC 214
LK + +E ++ +E EK++ K ++R+L + L E
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 263
Query: 215 SVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEK 274
SVS+ + V E+ + + R+ +Q E++ E+ + ER ++ + K+ + E+
Sbjct: 264 SVSAKLQAQVEEN-------ELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEE 316
Query: 275 AASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIG 334
+E+ W K + + +E + + ++ + + E+ I
Sbjct: 317 KMRRQEEMM---WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 373
Query: 335 DEKDKRPGSLETCRRESNPRQNQEFSFGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSA 394
+++ ++ + R+E R+ +E +R + + EE
Sbjct: 374 EQEKRQEQEAKMWRQEEKIREQEE----KIREQEEMMQEQEE------------------ 411
Query: 395 LVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHVPEDPREKS 454
K E+ W + + +++ ++ E ++ + + E
Sbjct: 412 ---------------KMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE------ 450
Query: 455 QDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQ 514
Q+E +R+ + + G + + +EK + + I+ + E E+
Sbjct: 451 QEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEK 510
Query: 515 LKVQLEKANKFKETITQIPKKSGVENEDQQE 545
++ Q E + +E + + +K + E QE
Sbjct: 511 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 62.0 bits (149), Expect = 2e-09
Identities = 88/386 (22%), Positives = 156/386 (40%), Gaps = 58/386 (15%)
Query: 76 VKKKKKKDKHSKKAK------KEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPD 129
VKK K K KH K K +E K KS +YE + + SD + E++ +
Sbjct: 629 VKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLK 688
Query: 130 KEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVS------SSSLKAEKETMRKIEQE 183
++ K+EK K ++ EW+ D S+K + S S + EK+ K E+E
Sbjct: 689 HDRDHFKKEEKLSK---MKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKE 745
Query: 184 KNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQ 243
+ +L++ E +L Y ++ +D K + ED K + KE+
Sbjct: 746 R--SLKEKSPKEEKLRLYKEE--RKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEK 801
Query: 244 AEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNC---- 299
+K+ ED + Y + F LE+ + S +D +R+RW +SD + +
Sbjct: 802 LKKEKVYREDSAFDEYCNKNQF---LENEDTKFSLSDD-QRDRW----FSDLSDSSFDFK 853
Query: 300 -QESRESDLVKYGNSSRDRYA--TTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQN 356
++S +S + Y + D A +T K + E+ RR+S R+
Sbjct: 854 GEDSWDSPVTDYRDMKSDSVAKLILETVKEDSKER----------------RRDSRAREK 897
Query: 357 QEFSFGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERL 416
+++ R F R D + L +S+ RK + S G L +K +++E
Sbjct: 898 RDY-----REPFFRKKDRDYLDKNSEKRKEQTEKHKS---VPGYLSEKDKKRRESAEAGR 949
Query: 417 TSWSRSDGRGDKKHSNQKPSETSTDE 442
+ +++ KP E +E
Sbjct: 950 DRKDALESCKERRDGRAKPEEAHREE 975
Score = 57.0 bits (136), Expect = 8e-08
Identities = 123/613 (20%), Positives = 230/613 (37%), Gaps = 100/613 (16%)
Query: 11 RFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQF 70
R ESA++ +RK+ + + +AK E KE G D + +E +
Sbjct: 941 RRESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPW 1000
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDK 130
+ H ++K+KKD K E+K+K+K ++Y++ + D S S E + DK
Sbjct: 1001 ERHHPAREKEKKDGPDK----ERKEKTKPERYKEKSSDKDKSEKSILEKCQK------DK 1050
Query: 131 EKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQ 190
E K++K K+ K + D ++ K EK I ++ ++ +
Sbjct: 1051 EFDKCFKEKKDTKE-----KHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDD 1105
Query: 191 SKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRN 250
K E+ Y D T +D + + E L R L+ KE+
Sbjct: 1106 KKGKEKSW--YIADIFTDESEDDRDSCMGSGFKMGEASDLP--RTDGLQEKEEGR----- 1156
Query: 251 FEDIVAERYGSMEIFQSKLEDAEKAASTKE--DYRRERWRKPTYSDKAQNC----QESRE 304
E Y S +S + + KE D R++R DK + +E ++
Sbjct: 1157 ------EAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKD 1210
Query: 305 SDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNL 364
+ + +DR A+ D+ ++ N++ + ++ +K+ + + + + + ++E
Sbjct: 1211 KESTEKYKDRKDR-ASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKE------ 1263
Query: 365 RAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDG 424
HSK RK SS + A+ SL K EE L +
Sbjct: 1264 ---------------HSKERK-----SSRSADAEKSLLE------KLEEEALHEY----- 1292
Query: 425 RGDKKHSNQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPERES 484
++ SN K SE S+D ++P + EV +PP + R++ E+E
Sbjct: 1293 ---REDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACLPEKLKEKER 1349
Query: 485 IHILSVDEKNKLGAKIIKAEMMGNMELAEQLKV--QLEKANKFKETITQIP-------KK 535
S K + K E E E K + + ++++ + K
Sbjct: 1350 HRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEGGSRKDSGQYEKDFLEADAYGVSYNMK 1409
Query: 536 SGVENEDQQEVILVRTDQSGRVWPVNTPGKSLE--------------SQGGRRKRQMVST 581
+ +E+E + + L T++ + P K +E + +R++
Sbjct: 1410 ADIEDELDKTIELFSTEKKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKW 1469
Query: 582 HEERERVRYFHDD 594
+E+ER R H D
Sbjct: 1470 RDEKERHRDRHAD 1482
Score = 49.7 bits (117), Expect = 1e-05
Identities = 104/498 (20%), Positives = 185/498 (37%), Gaps = 104/498 (20%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVN-------- 64
+S K+I + + + +VL+ + +F+KEE+ ++K E W+ D
Sbjct: 667 KSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKL--EEKEWLFKDEKSLKRIKDT 724
Query: 65 ------------ERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQ--KYEKNNESSD 110
+R + +E S+K+K K++ + K+E+KKKSK + K EK N+ +
Sbjct: 725 NKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKE 784
Query: 111 SSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSL 170
S E E + KE K+K EK ++D+ DE+
Sbjct: 785 DKISKEKEKI--------FKEDKEKLKKEKVYREDSAF---DEYC--------------- 818
Query: 171 KAEKETMRKIEQEKNQALEQSKL---MERELNPYW----KDGGTGLPPEDCSVSSITKVS 223
KNQ LE + + W D ED S +T
Sbjct: 819 ------------NKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYR 866
Query: 224 VVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYR 283
++ ++ K L ++ K+ R +R F+ K D S K +
Sbjct: 867 DMKSDSVA---KLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNSEKRKEQ 923
Query: 284 RERWRK-PTY-SDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRP 341
E+ + P Y S+K + +ES E + RDR ++ K + + +E +
Sbjct: 924 TEKHKSVPGYLSEKDKKRRESAE--------AGRDRKDALESCKERRDGRAKPEEAHRE- 974
Query: 342 GSLETCRRESNPRQNQEFSFGN----------LRAKFLRPSDDEELSFHSKGRKFEPLSS 391
L+ C ES + + FG R K + D+E +K +++ SS
Sbjct: 975 -ELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSS 1033
Query: 392 SSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKK--HSNQKPSETSTDEHQHVPED 449
S S K K+ E + D + K H K + S D+ ++
Sbjct: 1034 DK----DKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQ----GKE 1085
Query: 450 PREKSQDEVLRDDPPKKE 467
+EK+ ++ +D +K+
Sbjct: 1086 KKEKAFPGIISEDFSEKK 1103
Score = 42.0 bits (97), Expect = 0.003
Identities = 96/488 (19%), Positives = 185/488 (37%), Gaps = 86/488 (17%)
Query: 19 EERKEQTRNARAEVLRQAKANF----------EKEERRKELKRLRGEDTWMLPDVNERIE 68
E+ KE+ R++RA R + F + E+RKE L + +++
Sbjct: 883 EDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRR 942
Query: 69 QFSQEHSVKK---KKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPS 125
+ ++ +K + K++ +AK E+ + + ++ + D S + +E
Sbjct: 943 ESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWER 1002
Query: 126 QTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKN 185
P +EK K +K K+ T+ + K SS K+EK + K +++K
Sbjct: 1003 HHPAREKEKKDGPDKERKEKTKPER-----------YKEKSSDKDKSEKSILEKCQKDK- 1050
Query: 186 QALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAE 245
E + +K+ TK + G RK+ L + E
Sbjct: 1051 -----------EFDKCFKE------------KKDTKEKHKDTHGKDKERKASL--DQGKE 1085
Query: 246 KQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRES 305
K+ + F I++E F K +D K+ + + ++D++++ ++S
Sbjct: 1086 KKEKAFPGIISED------FSEKKDD-------KKGKEKSWYIADIFTDESEDDRDSCMG 1132
Query: 306 DLVKYGNSS--------------RDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRES 351
K G +S R+ YA+ D + S++++ +KDK P R +
Sbjct: 1133 SGFKMGEASDLPRTDGLQEKEEGREAYAS-DRHRKSSDKQHPERQKDKEPRDRRKDRGAA 1191
Query: 352 NP-RQNQEFSFGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTK 410
+ R +E F + K D+E + K RK + S S + + K
Sbjct: 1192 DAGRDKKEKVFEKHKEK-----KDKESTEKYKDRK-DRASVDSTQDKKNKQKLPEKAEKK 1245
Query: 411 NSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLR 470
++ E S+ + DK+HS ++ S S D + + E E++ E D K +
Sbjct: 1246 HAAEDKAK-SKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVS 1304
Query: 471 DTKSTFAG 478
T G
Sbjct: 1305 SDSFTDRG 1312
Score = 35.0 bits (79), Expect = 0.31
Identities = 106/539 (19%), Positives = 186/539 (34%), Gaps = 137/539 (25%)
Query: 75 SVKKKKKKDKHSKKAKKEKKKKS-----KKQKYEKNNESSDSSSSSEDE----------- 118
+ K++K+K+K KK KKE K + + K+ + S+SS S ED+
Sbjct: 444 NAKQQKEKNKVKKKRKKETKGREVRFGKRSDKFCSSESESESSESGEDDRDSLGSSGCLK 503
Query: 119 -----------WVEAVPSQTPDKEKAWKVKDEKSGKDD-TQIIKRDEWMTVDFMSVKTVS 166
+ S T + K S D T+ + D W T+ + VS
Sbjct: 504 GSPLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVS 563
Query: 167 S-------------------SSLKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGT 207
S SS+++ K ++ E K +L + K +P+
Sbjct: 564 SLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEKK------SPFLSSAEG 617
Query: 208 GLPPEDCSVSSITK--------------VSVVEDGGLSWLRKSYLRMKEQAEKQSRNFED 253
+P D + K S+ ++ L Y K++++K D
Sbjct: 618 AVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLEND 677
Query: 254 IVAERYGSM------------EIFQSKLEDAE----------KAASTKEDYRRERWRKPT 291
+ E + ++ + KLE+ E + T +D R +
Sbjct: 678 LSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKD 737
Query: 292 YSDKAQNCQESRESD---------LVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDK-RP 341
S+KA+ + +E + S+DR + + KN E I EK+K
Sbjct: 738 RSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLE-KKNDLKEDKISKEKEKIFK 796
Query: 342 GSLETCRRESNPRQNQEFSFGNLRAKFLRPSDDE-ELSFHSKGRKFEPLSSSS----ALV 396
E ++E R++ F + +FL D + LS + R F LS SS
Sbjct: 797 EDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGED 856
Query: 397 AQGSLCSGFRKPTKNSEERL--------TSWSRSDGRGDKKHSNQKP------------- 435
+ S + +R +S +L + R D R +K ++P
Sbjct: 857 SWDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKN 916
Query: 436 ---SETSTDEHQHVP-----EDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIH 486
+ T++H+ VP +D + + E RD +K+ L K G + E H
Sbjct: 917 SEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRD---RKDALESCKERRDGRAKPEEAH 972
Score = 32.7 bits (73), Expect = 1.5
Identities = 85/412 (20%), Positives = 157/412 (38%), Gaps = 61/412 (14%)
Query: 80 KKKDKHSKKAKKEKKKKSKKQKYE------KNNESSDSSSSSEDEWVEAVPSQTPDKEKA 133
K ++ + K +KEK K KK+K E + + SD SSE E E+ S D++
Sbjct: 438 KTREPSNAKQQKEKNKVKKKRKKETKGREVRFGKRSDKFCSSESE-SESSESGEDDRDSL 496
Query: 134 WKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQE-KNQALEQSK 192
K + ++ +D + + T S S A+K+ +Q K+ + K
Sbjct: 497 GSSGCLKG----SPLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWK 552
Query: 193 LMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFE 252
+ +P W E S+S T+ + + S S +K ++Q
Sbjct: 553 TIS---SPAWS--------EVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKR 601
Query: 253 DIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQ-NCQESRESDLVKYG 311
++E+ F S E A + ++ K + +K + C S+E L +
Sbjct: 602 ASLSEKKSP---FLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFT 658
Query: 312 NSSRDRYATTDTA-------KNSNNEKFIGDEKD--KRPGSLETCRRESNPRQNQEFSFG 362
D +D A N K + ++D K+ L + E +E+ F
Sbjct: 659 YEYEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLE-----EKEWLFK 713
Query: 363 NLRAKFLRPSDDEELSFHSKGRKF-EPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSR 421
+ ++ ++++S R F E S+ + SL K EE+L +
Sbjct: 714 DEKSLKRIKDTNKDIS-----RSFREEKDRSNKAEKERSL-----KEKSPKEEKLRLYKE 763
Query: 422 SDGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTK 473
KK S +PS+ ++ + ED K ++++ ++D KE L+ K
Sbjct: 764 E----RKKKSKDRPSK--LEKKNDLKEDKISKEKEKIFKED---KEKLKKEK 806
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 58.5 bits (140), Expect = 3e-08
Identities = 123/675 (18%), Positives = 250/675 (37%), Gaps = 74/675 (10%)
Query: 15 AKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEH 74
A+ + R + E+ +A E+EE R + L+ E M ++ E EQ +E
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEER--CQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 75 SVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAW 134
S ++K + +K + +AK +K ++ + ++N + + ED E + T ++EK+
Sbjct: 957 SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS- 1015
Query: 135 KVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLM 194
K ++ + E M D + ++T RK+E + +Q +
Sbjct: 1016 --------KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAEL 1067
Query: 195 ERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRK-----SYLRMKEQAEKQSR 249
+ ++ +++ + + + ++ L +R+ S L+ ++E+ SR
Sbjct: 1068 QAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASR 1127
Query: 250 NFEDIVAERYG-SMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLV 308
N + G +E +++LED + + +++ R +R ++ K +E++ +
Sbjct: 1128 NKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE-EEAKTHEAQ 1186
Query: 309 KYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRAKF 368
+ A + A+ K + +K +LE N+ N
Sbjct: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE----------NERGELANEVKVL 1236
Query: 369 LRPSDDEELSFHSKGRKFEPLSSSSALVAQG-----SLCSGFRKPTKNSEERLTSWSRSD 423
L+ D E H + + L +G L K + S+SD
Sbjct: 1237 LQGKGDSE---HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSD 1293
Query: 424 GRGDKKHSNQKPSETSTDEHQH-VPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPER 482
+ K + E+ + Q + E+ R+K K + + D K++F E
Sbjct: 1294 SKSSKLTKDFSALESQLQDTQELLQEENRQKLSLST------KLKQVEDEKNSFREQLEE 1347
Query: 483 E------------SIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEK-----ANKF 525
E ++H D K K+ + +G +E AE++K +L+K + +
Sbjct: 1348 EEEAKHNLEKQIATLHAQVADMKKKM------EDSVGCLETAEEVKRKLQKDLEGLSQRH 1401
Query: 526 KETITQIPKKSGVENEDQQEV--ILVRTD-QSGRVWPVNTPGKSLESQGGRRKRQMVSTH 582
+E + K + QQE+ +LV D Q + K + K
Sbjct: 1402 EEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYA 1461
Query: 583 EERERVRYFHDDDNLSLNDLVK-----NEKMGTAENQNKLFMRMASKFMGKTDGDYYTLD 637
EER+R + L + E+ E NK F M D ++
Sbjct: 1462 EERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVH 1521
Query: 638 DMFVSKAAERERLGE 652
++ SK A +++ E
Sbjct: 1522 ELEKSKRALEQQVEE 1536
Score = 37.7 bits (86), Expect = 0.048
Identities = 39/200 (19%), Positives = 88/200 (44%), Gaps = 7/200 (3%)
Query: 1 MATSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWML 60
+A +A +SG+ A + R E E L + + N E R LK+ + +
Sbjct: 1706 LADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDR--LKKANLQIDQIN 1763
Query: 61 PDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV 120
D+N + + +++ ++ K K ++ + + K KY+ + + ++ + +E +
Sbjct: 1764 TDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQL 1823
Query: 121 EAVPSQTPDKEKAWKV--KDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMR 178
+ ++T +++ A K + EK KD + + + +S+ LK K +
Sbjct: 1824 D---NETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLE 1880
Query: 179 KIEQEKNQALEQSKLMEREL 198
+ E+E +A + ++REL
Sbjct: 1881 EAEEEAQRANASRRKLQREL 1900
Score = 32.7 bits (73), Expect = 1.5
Identities = 109/599 (18%), Positives = 223/599 (37%), Gaps = 91/599 (15%)
Query: 1 MATSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWML 60
M M + G E+A+ ++ + ++ ++ + A ++K E+ K RL+ E +L
Sbjct: 1369 MKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKT--RLQQELDDLL 1426
Query: 61 PDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV 120
D++ Q S +KK K + E+K S K E++ +++
Sbjct: 1427 VDLDH------QRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALS 1480
Query: 121 EAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKI 180
A + ++KA + K + + + D MS K S+ +++ R +
Sbjct: 1481 LARALEEAMEQKAELERLNKQFRTEME----------DLMSSKDDVGKSVHELEKSKRAL 1530
Query: 181 EQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRM 240
EQ+ + Q + +E EL ED + + ++ + +
Sbjct: 1531 EQQVEEMKTQLEELEDELQ----------ATEDAKLRLEVNLQAMK----AQFERDLQGR 1576
Query: 241 KEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEK----AASTKEDYRRERWRKPTYSDKA 296
EQ+E++ + V E +++LED K A + ++ + + D A
Sbjct: 1577 DEQSEEKKKQLVRQVRE-------MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSA 1629
Query: 297 QNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFI-GDEKDKRPGSLETCRRESNPRQ 355
++ L K +D D + S E E +K+ S+ E+ Q
Sbjct: 1630 NKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSM-----EAEMIQ 1684
Query: 356 NQEFSFGNLRAKFLRPSDDEELS---FHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNS 412
QE RAK + +EL+ +S G+ L L A + +
Sbjct: 1685 LQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA---------RIAQLE 1735
Query: 413 EERLTSWSRSDGRGDK-KHSNQKPSETSTD---EHQHVPEDPREKSQDEVLRDDPPKKEH 468
EE ++ D+ K +N + + +TD E H ++ E ++ ++ R + K
Sbjct: 1736 EELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKN--ENARQQLERQNKELKVK 1793
Query: 469 LRDTKSTFAGSPERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKET 528
L++ + T V K K ++A++ QL+ QL+ K ++
Sbjct: 1794 LQEMEGT--------------VKSKYKASITALEAKI-------AQLEEQLDNETKERQA 1832
Query: 529 ITQIPKKSGVENEDQQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERER 587
+ +++ + ++V+L D+ ++ + KRQ+ EE +R
Sbjct: 1833 ACKQVRRT---EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQR 1888
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 58.2 bits (139), Expect = 3e-08
Identities = 138/734 (18%), Positives = 270/734 (36%), Gaps = 80/734 (10%)
Query: 1 MATSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWML 60
+A + A + F A+ + R + E+L ++ E+EE R ++ L+ E M
Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQI--LQNEKKKMQ 949
Query: 61 PDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV 120
+ + EQ +E ++K + +K + +AK +K ++ ++N++ ED
Sbjct: 950 AHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIA 1009
Query: 121 EAVPSQTPDKEKAWKV-----KDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKE 175
E ++EKA + K E D + +K++E + K ++
Sbjct: 1010 ECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD 1069
Query: 176 TMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRK 235
+ +++ + ++ Q E EL G E ++ KV ++ L++
Sbjct: 1070 QIAELQAQIDELKLQLAKKEEELQGALARG----DDETLHKNNALKVVRELQAQIAELQE 1125
Query: 236 SYLRMK---EQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTY 292
+ K +AEKQ R+ + +E +++LED + +++ R +R ++
Sbjct: 1126 DFESEKASRNKAEKQKRDLSE-------ELEALKTELEDTLDTTAAQQELRTKREQEVAE 1178
Query: 293 SDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRE-- 350
KA +E++ + R A + ++ K +K LET +E
Sbjct: 1179 LKKALE-EETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELA 1237
Query: 351 -------------SNPRQNQEFSFGNLRAKFLRPSDDEELSFHSKGRKFE-PLSSSSALV 396
+ R+ + L AK + D + K K + L + S L+
Sbjct: 1238 CEVKVLQQVKAESEHKRKKLDAQVQELHAK-VSEGDRLRVELAEKASKLQNELDNVSTLL 1296
Query: 397 AQGSL--------CSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHVPE 448
+ + ++++E L +R + + + S E Q E
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEE 1356
Query: 449 DPREKSQDEVLR-------------DDPPKKEHLRDTKSTFAGSPERESIHILSVDEKNK 495
+ R+ + +VL DD E L + K E S + +EK
Sbjct: 1357 EARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRL---EEKAL 1413
Query: 496 LGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENEDQQEVILVRTDQSG 555
K+ K + EL + L V L+ + + + KK +++ + ++
Sbjct: 1414 AYDKLEKTKNRLQQEL-DDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD 1472
Query: 556 RVWPVNTPGKSLESQGGRRKRQMVSTHEERER----VRYFHDDDNLSLNDLVKN----EK 607
R ++ R + + EE ER +R +D S +D+ KN EK
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEK 1532
Query: 608 MGTAENQNKLFMR-----MASKFMGKTDGDYYTLDDMFVSKAA-ERERLGEEEENQRKK- 660
A Q MR + + D +M KA ER+ +E+N+ KK
Sbjct: 1533 SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKR 1592
Query: 661 -AIAEHRSLAAQME 673
I + R L A++E
Sbjct: 1593 LLIKQVRELEAELE 1606
Score = 46.2 bits (108), Expect = 1e-04
Identities = 121/719 (16%), Positives = 283/719 (39%), Gaps = 98/719 (13%)
Query: 12 FESAKSIEERKEQTRNARAEVLRQAKANFEKE----ERRKELKRLRGEDTWMLPDVNERI 67
FES K+ + E+ + +E L K E ++EL+ R ++ + ++ + +
Sbjct: 1127 FESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQE---VAELKKAL 1183
Query: 68 EQFSQEHSVKKKKKKDKH-------SKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV 120
E+ ++ H + + + +H S++ ++ K+ K+ +K ++ E+ + + E + +
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1243
Query: 121 EAVPSQTPDKEKAWKVKDE----KSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKET 176
+ V +++ K K + + K + D ++ E + + VS+ +AEK+
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
Query: 177 MRKIEQE---KNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWL 233
++ + ++Q + +L++ E E+ +S+ + E+ L
Sbjct: 1304 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEE-EKNSLQEQQEEEEEARKNL 1362
Query: 234 RKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYS 293
K L ++ Q + +D + E + L+DAE + E+ K
Sbjct: 1363 EKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE-------KALAY 1415
Query: 294 DKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNP 353
DK + + + +L D + ++++ + +K+ + E
Sbjct: 1416 DKLEKTKNRLQQEL-------------DDLTVDLDHQRQVASNLEKKQKKFDQLLAEEK- 1461
Query: 354 RQNQEFSFGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSE 413
++ A++ D E K K LS + AL F + K
Sbjct: 1462 ---------SISARYAEERDRAEAEAREKETK--ALSLARALEEALEAKEEFERQNKQLR 1510
Query: 414 ERLTS-WSRSDGRGDKKHSNQKPSETSTDEHQHVP------EDPREKSQDEVLRDD---- 462
+ S D G H +K + + + ED + ++D LR +
Sbjct: 1511 ADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQ 1570
Query: 463 PPKKEHLRDTKSTFAGSPERESIHILSV-------DEKNKLGAKIIKAEMMGNMELAEQL 515
K + RD ++ + E++ + I V +++ K A + ++ ++L + L
Sbjct: 1571 AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKD-L 1629
Query: 516 KVQLEKANKFKETITQIPKKSGVENEDQQEVILVRTDQSGRVWPVNTPG----KSLESQG 571
+ Q+E ANK ++ + + +K + +D Q + ++ + KSLE++
Sbjct: 1630 EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEI 1689
Query: 572 GRRKRQMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGTA---ENQNKLFMRMA--SKFM 626
+ + ++ S+ ER R + + L D + N G + + + +L R+A + +
Sbjct: 1690 LQLQEELASS----ERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEEL 1745
Query: 627 GKTDGDYYTLDDMF-----------VSKAAERERLGEEEENQRKKAIAEHRSLAAQMEK 674
+ + L+D F AAER ++ +N R++ +++ L A++++
Sbjct: 1746 EEEQSNMELLNDRFRKTTLQVDTLNAELAAERS-AAQKSDNARQQLERQNKELKAKLQE 1803
Score = 38.5 bits (88), Expect = 0.028
Identities = 68/318 (21%), Positives = 139/318 (43%), Gaps = 43/318 (13%)
Query: 16 KSIEERKEQTRNARAEVLRQA-KANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEH 74
K +E + E AR EV++Q K + ++ ++EL+ R R E F+Q
Sbjct: 1627 KDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARAS----------RDEIFAQSK 1676
Query: 75 SVKKKKKK------DKHSKKAKKEKKKKSKKQKYEK------NNESSDSSSSSEDEWVEA 122
+KK K + A E+ ++ +Q+ ++ N+ S S+ E +EA
Sbjct: 1677 ESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEA 1736
Query: 123 VPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQ 182
+Q ++ +++E+S + R + VD ++ + + S + + R+ +
Sbjct: 1737 RIAQLEEE-----LEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLE 1791
Query: 183 EKNQALEQSKLMERE--LNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWL-RKSYLR 239
+N+ L+ +KL E E + +K + L + + + E + L R++ +
Sbjct: 1792 RQNKELK-AKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKK 1850
Query: 240 MKE---QAEKQSRN---FEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYS 293
+KE Q E + R+ +++ + + M+ + +LE+AE+ A+ RR+ R+
Sbjct: 1851 LKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRE---L 1907
Query: 294 DKAQNCQE--SRESDLVK 309
D A E SRE +K
Sbjct: 1908 DDATEANEGLSREVSTLK 1925
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 58.2 bits (139), Expect = 3e-08
Identities = 114/586 (19%), Positives = 239/586 (40%), Gaps = 86/586 (14%)
Query: 37 KANFEKEERRKELKRLRGEDTWMLPDVNERIEQFS-QEHSVKKKKKKDKHSKKAKKEKKK 95
KA+ + + +E K ++ E + + E+ + +E KK +K+K +++K+
Sbjct: 1056 KAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKR 1115
Query: 96 KSKKQKYEKNNESSDSSSSSED--EWVEAVPSQT--PDKEKAWKV--KDEKSGKDDTQII 149
K++++ +K+ ESS S + E V+ P + PD EK + KD+ S + I
Sbjct: 1116 KTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKI 1175
Query: 150 KRDEWMTVDFMSVKTVSSSSLKAEK--ETMRKIEQEKNQALEQSKLMERE-----LNPYW 202
K + S + +S++ +EK T K++QEK + + K+ E L Y
Sbjct: 1176 KLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYT 1235
Query: 203 KDGGTG-LPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDI-----VA 256
TG P + TK +V++ M+E + ED+ V
Sbjct: 1236 STSSTGGSPVRKSEEKTDTKRTVIKT------------MEEYNNDNTAPAEDVIIMIQVP 1283
Query: 257 ERYGSMEIFQSKLEDAE---------------KAASTK-EDYRRERWRKPTYSDKAQNCQ 300
+ + F+S+ ED + K STK + + ++ S+K Q
Sbjct: 1284 QSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFT 1343
Query: 301 ESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEK--DKRPGSLETCRRESNPRQNQE 358
+ +++++ S A+++ K + + + +++ +KR S + + + R N++
Sbjct: 1344 KDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQ 1403
Query: 359 FSFGNLR--AKFLRPSDDEELSFHSKGRKFEP------------LSSSSALVAQGSLCSG 404
+F +L +K R SD + + S + F P SSS + L
Sbjct: 1404 GNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRR 1463
Query: 405 FRKPTKNSEERLTSWSR--------SDGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQD 456
P++N + ++ G GD K SN PS D + +++
Sbjct: 1464 KDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEE 1523
Query: 457 EVLRDDPP---KKEHLRDTKSTFAGSPERESIHILSVDEKNKLGAKIIKAEMMGNMELAE 513
D P +++H+ + ++ S + ++IL+ E ++ K ++ G ++ +
Sbjct: 1524 TKSVDKNPCKDREKHVLEARNNKESSGNK-LLYILNPPE-----TQVEKEQITGQIDKST 1577
Query: 514 -QLKVQLEKANKFKETITQIPKKSGVE----NEDQQEVILVRTDQS 554
+ K QL +++ +T+ ++ E D + + V+ ++S
Sbjct: 1578 VKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEES 1623
Score = 42.4 bits (98), Expect = 0.002
Identities = 80/361 (22%), Positives = 130/361 (36%), Gaps = 36/361 (9%)
Query: 14 SAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQE 73
S S K +T++ VL EKE K + E L +NE+ S
Sbjct: 1358 SKNSASSEKGKTKDRDYSVL-------EKENPEKRKNSTQPEKESNLDRLNEQGNFKSLS 1410
Query: 74 HSVKKKKKKDKH-SKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEK 132
S K+ + DKH S +A K + K + SSS DE E T K+
Sbjct: 1411 QSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNEL----TRRKDS 1466
Query: 133 AWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSL-------KAEKETMRKIEQ--- 182
+ KD SG+ + +RD S K+ SS S KA +T R E+
Sbjct: 1467 PSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS 1526
Query: 183 -EKNQALEQSKLMERELNPYWKDGGTGL----PPEDCSVSSITKVSVVEDGGLSWLRKSY 237
+KN ++ K + N G L PPE V ++ + KS
Sbjct: 1527 VDKNPCKDREKHVLEARNNKESSGNKLLYILNPPE---------TQVEKEQITGQIDKST 1577
Query: 238 LRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQ 297
++ K Q SR D+ E + D+E S KE+ K +
Sbjct: 1578 VKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVE 1637
Query: 298 NCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQ 357
+ES ++ V SR++ ++ + S + G + S + + + ++ +
Sbjct: 1638 KAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKK 1697
Query: 358 E 358
+
Sbjct: 1698 K 1698
Score = 37.4 bits (85), Expect = 0.063
Identities = 62/273 (22%), Positives = 100/273 (36%), Gaps = 25/273 (9%)
Query: 62 DVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVE 121
D ER + ++ K+K SKK K K ++K + E S S + E
Sbjct: 971 DKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKE 1030
Query: 122 AVPSQTPDKEKAWKVKDEK----SGKDDTQIIK-RDEWMTVDFMSVKTVSSSSLKAEKET 176
P K + KDEK K ++ K E V VK S +K+EK T
Sbjct: 1031 ETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLT 1090
Query: 177 MR----KIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSW 232
+ K EKN+ L+ +K +R+ K +S + +V+
Sbjct: 1091 TKEEKAKKPNEKNKPLD-NKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRK 1149
Query: 233 L-----------RKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKED 281
+ K + + A+K N E ++ GS E + E +EK ST
Sbjct: 1150 MEPDTEKMDRTPEKDKISLSAPAKKIKLNRE--TGKKIGSTENISNTKEPSEKLESTSSK 1207
Query: 282 YRRERWRKPTYSDKAQNCQESRESDLVKYGNSS 314
++E+ + + E S LV Y ++S
Sbjct: 1208 VKQEKVKGKV--RRKVTGTEGSSSTLVDYTSTS 1238
Score = 37.0 bits (84), Expect = 0.082
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDK 130
S S + +D KK KKEKKK K +K++K+ + + + E K
Sbjct: 1679 SHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKH---KHKKKK 1735
Query: 131 EKAWKVKDEKSGKDDTQI 148
K K K+++ KDD ++
Sbjct: 1736 SKKNKDKEKEKEKDDQKV 1753
Score = 36.2 bits (82), Expect = 0.14
Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 12/67 (17%)
Query: 69 QFSQEHSVKKKKKKDKHSKKAKKEKK--------KKSKKQKYE----KNNESSDSSSSSE 116
Q S++ KK+KKK K KK KK KK +KS+K K++ K N+ + +
Sbjct: 1690 QDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1749
Query: 117 DEWVEAV 123
D+ V++V
Sbjct: 1750 DQKVKSV 1756
Score = 35.0 bits (79), Expect = 0.31
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 4/81 (4%)
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDK 130
++ HS + + SKK K+KKK+ KK K K ++ + +E E +E K
Sbjct: 1677 TRSHSSSASSAESQDSKK--KKKKKEKKKHKKHKKHKKHKKHAGTEVE-LEKSQKHKHKK 1733
Query: 131 EKAWKVKD-EKSGKDDTQIIK 150
+K+ K KD EK + D Q +K
Sbjct: 1734 KKSKKNKDKEKEKEKDDQKVK 1754
Score = 34.7 bits (78), Expect = 0.41
Identities = 89/454 (19%), Positives = 181/454 (39%), Gaps = 77/454 (16%)
Query: 266 QSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAK 325
+SK +++E A + + ++ RK K + + +L++ SR+ T +
Sbjct: 881 KSKEKESENAPGDGKGNKHKKHRKRR---KGEESEGFLNPELLETSRKSRE---PTGVEE 934
Query: 326 NSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRAKFLRPSDDEELSFHSKGRK 385
N + F+ +D + P + +F ++ K R D + +KG K
Sbjct: 935 NKTDSLFVLPSRD------DATPVRDEPMDAESITFKSVSEKDKRERDKPK----AKGDK 984
Query: 386 FEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGD---KKHSNQKP------S 436
+ + SA+ + ++ KP K +E++ R + KK + P S
Sbjct: 985 TKRKNDGSAVSKKENIV----KPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKS 1040
Query: 437 ETSTDEHQHVPEDPR--------EKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHIL 488
+S+ + + + PR E + + ++++ KK++ +D KS + E ++
Sbjct: 1041 SSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKA---K 1097
Query: 489 SVDEKNK----LGAK-IIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENEDQ 543
+EKNK G K K E G + E +++ K +T+I K S +
Sbjct: 1098 KPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLE-----VTEIVKPSPKRKMEP 1152
Query: 544 QEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLNDLV 603
+ RT + ++ ++ P K ++ RE + +N+S N
Sbjct: 1153 DTEKMDRTPEKDKI-SLSAPAKKIKL--------------NRETGKKIGSTENIS-NTKE 1196
Query: 604 KNEKMGTAEN---QNKLFMRMASKFMGKTDGDYYTLDDMFVSKAAERERLGEEEENQRKK 660
+EK+ + + Q K+ ++ K G T+G TL D + + + + EE K
Sbjct: 1197 PSEKLESTSSKVKQEKVKGKVRRKVTG-TEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTK 1255
Query: 661 AIAEHRSLAAQMEKCLYCFDSSQFPKHLIVAIGV 694
R++ ME+ Y D++ + +I+ I V
Sbjct: 1256 -----RTVIKTMEE--YNNDNTAPAEDVIIMIQV 1282
Score = 32.3 bits (72), Expect = 2.0
Identities = 26/97 (26%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 3 TSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPD 62
+S + + R S + R + + AE + +K +K+E++K K + +
Sbjct: 1660 SSPSVSPSRSHSPSGSQTRSHSSSASSAES-QDSKKKKKKKEKKKHKKHKKHKKHKKHAG 1718
Query: 63 VNERIEQFSQEHSVKKKK-KKDKHSKKAKKEKKKKSK 98
+E+ SQ+H KKKK KK+K +K K++ +K K
Sbjct: 1719 TEVELEK-SQKHKHKKKKSKKNKDKEKEKEKDDQKVK 1754
Score = 32.3 bits (72), Expect = 2.0
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 6/74 (8%)
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEK 132
+ S KKKKKK+K KK KK K K+ + + S + + + + DKEK
Sbjct: 1690 QDSKKKKKKKEK-----KKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEK 1744
Query: 133 AWKVKDEKSGKDDT 146
K KD++ K T
Sbjct: 1745 E-KEKDDQKVKSVT 1757
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 58.2 bits (139), Expect = 3e-08
Identities = 114/586 (19%), Positives = 239/586 (40%), Gaps = 86/586 (14%)
Query: 37 KANFEKEERRKELKRLRGEDTWMLPDVNERIEQFS-QEHSVKKKKKKDKHSKKAKKEKKK 95
KA+ + + +E K ++ E + + E+ + +E KK +K+K +++K+
Sbjct: 1090 KAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKR 1149
Query: 96 KSKKQKYEKNNESSDSSSSSED--EWVEAVPSQT--PDKEKAWKV--KDEKSGKDDTQII 149
K++++ +K+ ESS S + E V+ P + PD EK + KD+ S + I
Sbjct: 1150 KTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKI 1209
Query: 150 KRDEWMTVDFMSVKTVSSSSLKAEK--ETMRKIEQEKNQALEQSKLMERE-----LNPYW 202
K + S + +S++ +EK T K++QEK + + K+ E L Y
Sbjct: 1210 KLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYT 1269
Query: 203 KDGGTG-LPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDI-----VA 256
TG P + TK +V++ M+E + ED+ V
Sbjct: 1270 STSSTGGSPVRKSEEKTDTKRTVIKT------------MEEYNNDNTAPAEDVIIMIQVP 1317
Query: 257 ERYGSMEIFQSKLEDAE---------------KAASTK-EDYRRERWRKPTYSDKAQNCQ 300
+ + F+S+ ED + K STK + + ++ S+K Q
Sbjct: 1318 QSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFT 1377
Query: 301 ESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEK--DKRPGSLETCRRESNPRQNQE 358
+ +++++ S A+++ K + + + +++ +KR S + + + R N++
Sbjct: 1378 KDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQ 1437
Query: 359 FSFGNLR--AKFLRPSDDEELSFHSKGRKFEP------------LSSSSALVAQGSLCSG 404
+F +L +K R SD + + S + F P SSS + L
Sbjct: 1438 GNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRR 1497
Query: 405 FRKPTKNSEERLTSWSR--------SDGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQD 456
P++N + ++ G GD K SN PS D + +++
Sbjct: 1498 KDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEE 1557
Query: 457 EVLRDDPP---KKEHLRDTKSTFAGSPERESIHILSVDEKNKLGAKIIKAEMMGNMELAE 513
D P +++H+ + ++ S + ++IL+ E ++ K ++ G ++ +
Sbjct: 1558 TKSVDKNPCKDREKHVLEARNNKESSGNK-LLYILNPPE-----TQVEKEQITGQIDKST 1611
Query: 514 -QLKVQLEKANKFKETITQIPKKSGVE----NEDQQEVILVRTDQS 554
+ K QL +++ +T+ ++ E D + + V+ ++S
Sbjct: 1612 VKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEES 1657
Score = 42.4 bits (98), Expect = 0.002
Identities = 80/361 (22%), Positives = 130/361 (36%), Gaps = 36/361 (9%)
Query: 14 SAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQE 73
S S K +T++ VL EKE K + E L +NE+ S
Sbjct: 1392 SKNSASSEKGKTKDRDYSVL-------EKENPEKRKNSTQPEKESNLDRLNEQGNFKSLS 1444
Query: 74 HSVKKKKKKDKH-SKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEK 132
S K+ + DKH S +A K + K + SSS DE E T K+
Sbjct: 1445 QSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNEL----TRRKDS 1500
Query: 133 AWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSL-------KAEKETMRKIEQ--- 182
+ KD SG+ + +RD S K+ SS S KA +T R E+
Sbjct: 1501 PSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKS 1560
Query: 183 -EKNQALEQSKLMERELNPYWKDGGTGL----PPEDCSVSSITKVSVVEDGGLSWLRKSY 237
+KN ++ K + N G L PPE V ++ + KS
Sbjct: 1561 VDKNPCKDREKHVLEARNNKESSGNKLLYILNPPE---------TQVEKEQITGQIDKST 1611
Query: 238 LRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQ 297
++ K Q SR D+ E + D+E S KE+ K +
Sbjct: 1612 VKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVE 1671
Query: 298 NCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQ 357
+ES ++ V SR++ ++ + S + G + S + + + ++ +
Sbjct: 1672 KAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKK 1731
Query: 358 E 358
+
Sbjct: 1732 K 1732
Score = 37.4 bits (85), Expect = 0.063
Identities = 62/273 (22%), Positives = 100/273 (36%), Gaps = 25/273 (9%)
Query: 62 DVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVE 121
D ER + ++ K+K SKK K K ++K + E S S + E
Sbjct: 1005 DKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKE 1064
Query: 122 AVPSQTPDKEKAWKVKDEK----SGKDDTQIIK-RDEWMTVDFMSVKTVSSSSLKAEKET 176
P K + KDEK K ++ K E V VK S +K+EK T
Sbjct: 1065 ETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLT 1124
Query: 177 MR----KIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSW 232
+ K EKN+ L+ +K +R+ K +S + +V+
Sbjct: 1125 TKEEKAKKPNEKNKPLD-NKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRK 1183
Query: 233 L-----------RKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKED 281
+ K + + A+K N E ++ GS E + E +EK ST
Sbjct: 1184 MEPDTEKMDRTPEKDKISLSAPAKKIKLNRE--TGKKIGSTENISNTKEPSEKLESTSSK 1241
Query: 282 YRRERWRKPTYSDKAQNCQESRESDLVKYGNSS 314
++E+ + + E S LV Y ++S
Sbjct: 1242 VKQEKVKGKV--RRKVTGTEGSSSTLVDYTSTS 1272
Score = 37.0 bits (84), Expect = 0.082
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDK 130
S S + +D KK KKEKKK K +K++K+ + + + E K
Sbjct: 1713 SHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKH---KHKKKK 1769
Query: 131 EKAWKVKDEKSGKDDTQI 148
K K K+++ KDD ++
Sbjct: 1770 SKKNKDKEKEKEKDDQKV 1787
Score = 36.2 bits (82), Expect = 0.14
Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 12/67 (17%)
Query: 69 QFSQEHSVKKKKKKDKHSKKAKKEKK--------KKSKKQKYE----KNNESSDSSSSSE 116
Q S++ KK+KKK K KK KK KK +KS+K K++ K N+ + +
Sbjct: 1724 QDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKD 1783
Query: 117 DEWVEAV 123
D+ V++V
Sbjct: 1784 DQKVKSV 1790
Score = 35.0 bits (79), Expect = 0.31
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 4/81 (4%)
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDK 130
++ HS + + SKK K+KKK+ KK K K ++ + +E E +E K
Sbjct: 1711 TRSHSSSASSAESQDSKK--KKKKKEKKKHKKHKKHKKHKKHAGTEVE-LEKSQKHKHKK 1767
Query: 131 EKAWKVKD-EKSGKDDTQIIK 150
+K+ K KD EK + D Q +K
Sbjct: 1768 KKSKKNKDKEKEKEKDDQKVK 1788
Score = 34.7 bits (78), Expect = 0.41
Identities = 89/454 (19%), Positives = 181/454 (39%), Gaps = 77/454 (16%)
Query: 266 QSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAK 325
+SK +++E A + + ++ RK K + + +L++ SR+ T +
Sbjct: 915 KSKEKESENAPGDGKGNKHKKHRKRR---KGEESEGFLNPELLETSRKSRE---PTGVEE 968
Query: 326 NSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRAKFLRPSDDEELSFHSKGRK 385
N + F+ +D + P + +F ++ K R D + +KG K
Sbjct: 969 NKTDSLFVLPSRD------DATPVRDEPMDAESITFKSVSEKDKRERDKPK----AKGDK 1018
Query: 386 FEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGD---KKHSNQKP------S 436
+ + SA+ + ++ KP K +E++ R + KK + P S
Sbjct: 1019 TKRKNDGSAVSKKENIV----KPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKS 1074
Query: 437 ETSTDEHQHVPEDPR--------EKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHIL 488
+S+ + + + PR E + + ++++ KK++ +D KS + E ++
Sbjct: 1075 SSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKA---K 1131
Query: 489 SVDEKNK----LGAK-IIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENEDQ 543
+EKNK G K K E G + E +++ K +T+I K S +
Sbjct: 1132 KPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLE-----VTEIVKPSPKRKMEP 1186
Query: 544 QEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLNDLV 603
+ RT + ++ ++ P K ++ RE + +N+S N
Sbjct: 1187 DTEKMDRTPEKDKI-SLSAPAKKIKL--------------NRETGKKIGSTENIS-NTKE 1230
Query: 604 KNEKMGTAEN---QNKLFMRMASKFMGKTDGDYYTLDDMFVSKAAERERLGEEEENQRKK 660
+EK+ + + Q K+ ++ K G T+G TL D + + + + EE K
Sbjct: 1231 PSEKLESTSSKVKQEKVKGKVRRKVTG-TEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTK 1289
Query: 661 AIAEHRSLAAQMEKCLYCFDSSQFPKHLIVAIGV 694
R++ ME+ Y D++ + +I+ I V
Sbjct: 1290 -----RTVIKTMEE--YNNDNTAPAEDVIIMIQV 1316
Score = 32.3 bits (72), Expect = 2.0
Identities = 26/97 (26%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 3 TSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPD 62
+S + + R S + R + + AE + +K +K+E++K K + +
Sbjct: 1694 SSPSVSPSRSHSPSGSQTRSHSSSASSAES-QDSKKKKKKKEKKKHKKHKKHKKHKKHAG 1752
Query: 63 VNERIEQFSQEHSVKKKK-KKDKHSKKAKKEKKKKSK 98
+E+ SQ+H KKKK KK+K +K K++ +K K
Sbjct: 1753 TEVELEK-SQKHKHKKKKSKKNKDKEKEKEKDDQKVK 1788
Score = 32.3 bits (72), Expect = 2.0
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 6/74 (8%)
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEK 132
+ S KKKKKK+K KK KK K K+ + + S + + + + DKEK
Sbjct: 1724 QDSKKKKKKKEK-----KKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEK 1778
Query: 133 AWKVKDEKSGKDDT 146
K KD++ K T
Sbjct: 1779 E-KEKDDQKVKSVT 1791
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 57.4 bits (137), Expect = 6e-08
Identities = 86/461 (18%), Positives = 189/461 (40%), Gaps = 41/461 (8%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
E + I E++E+ R ++ RQ + +EKEE+ R + E W + R E+
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK----MRRQEEMMWEKEEKMRRQEEMMW 373
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEK 132
E K +++++ +K +K ++ + K + EK E + E+E + + + K
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE--KRQEEEKIREQEKRQEQEAK 431
Query: 133 AWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSK 192
W+ ++EK + + +I ++++ M + E+E +R E+EK Q E+
Sbjct: 432 MWR-QEEKIREQEEKIREQEKKMWRQEEKIH---------EQEKIR--EEEKRQEQEEMW 479
Query: 193 LMERELN---PYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSR 249
E +++ W+ E+ KV E+ +R+ +++EQ EK R
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK----IREQEEKIREQEEKMWR 535
Query: 250 NFEDIVAERYGSMEIFQSKLEDAEK--AASTKEDYRRERWRKPTYSDKAQNCQES--RES 305
E I + M + K+ + EK +++ + WR+ +K + +E R+
Sbjct: 536 QEEKIREQE--EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ---EEKIREQEEKVWRQE 590
Query: 306 DLVKYGNSSR---DRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFG 362
+ ++ R + K E+ I ++++K E R + Q QE G
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG 650
Query: 363 NLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALV-AQGSLCSGFRKPTKNSEERLTSWSR 421
K + + + R+ E + + Q + + EE++ W +
Sbjct: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM--WEQ 708
Query: 422 SDGRGDKKHSNQKPSETSTDEHQHV-PEDPREKSQDEVLRD 461
+ +++ Q+ E + + + ++ R + Q+E +++
Sbjct: 709 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 48.1 bits (113), Expect = 4e-05
Identities = 68/378 (17%), Positives = 153/378 (40%), Gaps = 51/378 (13%)
Query: 12 FESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERI---- 67
+E + + ++E ++ RQ + +EKEE+ + + + E + ++ E++
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 68 ------EQFSQEHSVKKKKK---------------KDKHSKKAKKEKKKKSKKQKYEKNN 106
E+ +E +++++K +++ K ++EKK +++K +
Sbjct: 405 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 464
Query: 107 ESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDE--WMTVDFMSVKT 164
+ + E E + + ++E+ W+ K EK + + +I K++E W
Sbjct: 465 KIREEEKRQEQEEMWRQEEKIHEQEEIWRQK-EKMHEQEEKIRKQEEKVWR--------- 514
Query: 165 VSSSSLKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSV 224
++ ++E +R EQE+ ++ K+ E+E W++ E + K
Sbjct: 515 -QEEKIREQEEKIR--EQEEKMWRQEEKIREQE--EMWRE--EEKMHEQEKIWEEEKRQE 567
Query: 225 VEDGGLSWLRKSYLRMKEQ----AEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKE 280
ED W ++ +R +E+ E++ R E+ E+ M + K+ + E+ +E
Sbjct: 568 QED--KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625
Query: 281 DYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKR 340
+ RE+ K ++ QE + + + ++ + EK EK R
Sbjct: 626 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIR 685
Query: 341 PGSLETCRRESNPRQNQE 358
E R + Q QE
Sbjct: 686 EQE-EKIREQEEMMQEQE 702
Score = 47.4 bits (111), Expect = 6e-05
Identities = 39/193 (20%), Positives = 87/193 (45%), Gaps = 24/193 (12%)
Query: 11 RFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQF 70
R E + ++E+ R +V RQ + E+EE+R+E + E W
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQE----QEEKMW------------ 608
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDK 130
QE ++++++K + ++ +E+++K ++Q+ E E + E++ E +
Sbjct: 609 KQEEKIREQEEKIQEQEEKIREQEEKIREQE-EMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 131 EKAWKVKD-----EKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKN 185
E W+ ++ EK ++ + I+ E M + + ++E M+ EQE+
Sbjct: 668 ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ--EQEEK 725
Query: 186 QALEQSKLMEREL 198
++ K+ E+E+
Sbjct: 726 MRRQEEKMWEQEV 738
Score = 46.6 bits (109), Expect = 1e-04
Identities = 51/277 (18%), Positives = 121/277 (43%), Gaps = 33/277 (11%)
Query: 11 RFESAKSIEERKEQTRNARAEVLRQAKANFEKEER-RKELKRLRGEDTWMLPDVNERIEQ 69
+ + I +KE+ ++ +Q + + +EE+ R++ +++R ++ M + EQ
Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 543
Query: 70 FSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPD 129
+K +++K ++ K+++++ ++ EK E + E++ E +
Sbjct: 544 EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQ 603
Query: 130 KEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALE 189
+EK WK ++EK + + +I +++E + K + E+E K+ +++ + E
Sbjct: 604 EEKMWK-QEEKIREQEEKIQEQEE--KIREQEEKIREQEEMTQEQE--EKMGEQEEKMCE 658
Query: 190 QSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSR 249
Q + M+ + W+ +R+ +++EQ EK R
Sbjct: 659 QEEKMQEQEETMWRQE-------------------------EKIREQEKKIREQEEK-IR 692
Query: 250 NFEDIVAERYGSMEIFQSKL-EDAEKAASTKEDYRRE 285
E+++ E+ M + K+ E EK +E RR+
Sbjct: 693 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729
Score = 42.4 bits (98), Expect = 0.002
Identities = 96/564 (17%), Positives = 218/564 (38%), Gaps = 105/564 (18%)
Query: 32 VLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKAKK 91
V + +A E+ E L + + E W E+I+++ ++ +++K +++ K ++
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQ---EEKIQEWEEKIQEQEEKIREQEEKIREQ 333
Query: 92 EKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIKR 151
E+K + ++ E E + E+ E +E W+ K+EK + + + ++
Sbjct: 334 EEKMRRQE---EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE-KEEKMRRQEEMMWEK 389
Query: 152 DEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPP 211
+E + + K ++ ++E QE+ + EQ K E+E + ++
Sbjct: 390 EE--KIRELEEKMHEQEKIREQEEK----RQEEEKIREQEKRQEQEAKMWRQE------- 436
Query: 212 EDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLED 271
+R+ +++EQ +K R E I Q K+ +
Sbjct: 437 -------------------EKIREQEEKIREQEKKMWRQEEKIHE---------QEKIRE 468
Query: 272 AEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEK 331
EK +E +R+E + E E K ++ K E+
Sbjct: 469 EEKRQEQEEMWRQE-----------EKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517
Query: 332 FIGDEKDK-RPGSLETCRRESNPRQNQEFSFGNLRAKFLRPSDDEELSFHSKGRKFEPLS 390
I ++++K R + R+E R+ +E EE H + + +E
Sbjct: 518 KIREQEEKIREQEEKMWRQEEKIREQEEMW-------------REEEKMHEQEKIWEEEK 564
Query: 391 SSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHVPE-D 449
Q +R+ K E+ W + + +++ Q+ E + + + E +
Sbjct: 565 ------RQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 450 PREKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVDEKNKLGAKIIKAEMMGNM 509
+ + Q+E +R+ ++E +R+ + ++ +++ K+G + K
Sbjct: 619 EKIQEQEEKIRE---QEEKIREQEE-------------MTQEQEEKMGEQEEKM-----C 657
Query: 510 ELAEQLKVQLEKANKFKETITQIPKKSGVENEDQQEVILVRTDQSGRVW----PVNTPGK 565
E E+++ Q E + +E I + KK + E +E + +Q ++W + +
Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 717
Query: 566 SLESQGGRRKRQMVSTHEERERVR 589
++ Q + +RQ E+ R+R
Sbjct: 718 KMQEQEEKMRRQEEKMWEQEVRLR 741
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 57.0 bits (136), Expect = 8e-08
Identities = 120/600 (20%), Positives = 233/600 (38%), Gaps = 77/600 (12%)
Query: 41 EKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQ 100
EK + +K+ GE + + F KK K+ + K K K K+ +K+
Sbjct: 581 EKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKE 640
Query: 101 KYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGK-DDTQIIKRDEWMTVDF 159
K++K E ++D E S D+E WK KS + +D + E +T++
Sbjct: 641 KHKKEIEGEKEKYKTKDSAKELQRSVEFDRE-FWKENFFKSDETEDLFLNMEHESLTLE- 698
Query: 160 MSVKTVSSSSLKAEKETMRK-IEQEKNQALEQSKLMERELNPYWKDGGTGLPPE------ 212
K+ ++K +K T K + +E+N E+ K+ + + ++ L E
Sbjct: 699 --KKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPT 756
Query: 213 --DCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLE 270
D +S+ ++ E GL + K EKQ ++ ++ + +I + +E
Sbjct: 757 DKDSEFTSLGMSAIEESIGLHLVEKEI-----DIEKQEKHIKESKEKPEKRSQIKEKDIE 811
Query: 271 DAEKAASTKE-DYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNN 329
E+ KE + E + D ++ + +E D + Y + + + + +KN+
Sbjct: 812 KMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKL-YSHHTEKCHKEGEKSKNTAA 870
Query: 330 EKFIGDEKDKRPGSLETCRRESNPRQNQ---EFSFGNLRAKFLRPSDDEELSFHSKGRKF 386
K D+++K ++ + P + + E +L K + SD+ E S KG+
Sbjct: 871 IKKT-DDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNK 929
Query: 387 EPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHV 446
E K + ++ + S + KH ++ + D ++
Sbjct: 930 E-------------------KDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQ 970
Query: 447 PEDP---REKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVDEKNKLGAKIIKA 503
E P +EK++DE L+ K++ +D I E++K KI
Sbjct: 971 HEKPLSLKEKTKDEPLKTPDGKEKDKKDK-------------DIDRYKERDKHKDKIQIN 1017
Query: 504 EMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENEDQQEVILVRTDQSGRVWPVNTP 563
++ A++ K + A+K PK+ + N+D + R
Sbjct: 1018 SLLKLKSEADKPKPKSSPASKDTR-----PKEKRLVNDDLMQTSFERM----------LS 1062
Query: 564 GKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGTAENQNKLFMRMAS 623
K LE + +K + +E+ER+R + L + D K + T E++NK R S
Sbjct: 1063 LKDLEIEQWHKKHKEKIKQKEKERLRN-RNCLELKIKDKEKTKHTPT-ESKNKELTRSKS 1120
Score = 49.7 bits (117), Expect = 1e-05
Identities = 66/333 (19%), Positives = 132/333 (39%), Gaps = 45/333 (13%)
Query: 23 EQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKK 82
E+++N A K ++E+ R+++ R ++ P+ + + ++H ++KK K+
Sbjct: 863 EKSKNTAA-----IKKTDDREKSREKMDRKHDKEK---PEKERHLAESKEKHLMEKKNKQ 914
Query: 83 DKHSKKAKKEK-KKKSKKQKYEKNNESSDSSSSS--------EDEWVEAVPSQTPDKEKA 133
+S+ +K EK K K K ++ +K +S D S + E++ V EK
Sbjct: 915 SDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKP 974
Query: 134 WKVKDEKSGK-----DDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQAL 188
+K++ + D + K+D+ D K K + ++ K++ E ++
Sbjct: 975 LSLKEKTKDEPLKTPDGKEKDKKDK----DIDRYKERDKHKDKIQINSLLKLKSEADKPK 1030
Query: 189 EQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQS 248
+S ++ P K L +D +S ++ ++D + K + +Q EK
Sbjct: 1031 PKSSPASKDTRPKEK----RLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEK-- 1084
Query: 249 RNFEDIVAERYGSMEIFQSKLEDAEKAAST-KEDYRRERWRKPTYSDKAQNCQESRESDL 307
ER + + K++D EK T E +E R + +E + D
Sbjct: 1085 --------ERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDA 1136
Query: 308 VKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKR 340
V S+R + T F+ D R
Sbjct: 1137 V----SNRSQSVDTKNVMTLGKSSFVSDNSLNR 1165
Score = 46.2 bits (108), Expect = 1e-04
Identities = 113/607 (18%), Positives = 228/607 (37%), Gaps = 96/607 (15%)
Query: 19 EERKEQTRNARAEVLRQA-------KANFEKEERRKELKRLRGEDTWMLPDVNERIEQFS 71
E+ K +T+++ E+ R K NF K + ++L +N E +
Sbjct: 649 EKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDL------------FLNMEHESLT 696
Query: 72 QEHSVKKKKK-KDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDK 130
E K +K KD S K K K+++ K++ +K + S+ S E
Sbjct: 697 LEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREE-------------- 742
Query: 131 EKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKT-----VSSSSLKAEKETMRKIEQEKN 185
K+KD K +++ K E+ ++ +++ + + EK+ + I++ K
Sbjct: 743 ----KIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQE-KHIKESKE 797
Query: 186 QALEQSKLMERELNPYWK---DGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKE 242
+ ++S++ E+++ + + + E S +S D ++KE
Sbjct: 798 KPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVD-----------KIKE 846
Query: 243 QAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQES 302
+ + S + E E S K D + + K D + ++ KP +K ++ ES
Sbjct: 847 KDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDK-EKP---EKERHLAES 902
Query: 303 RESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFG 362
+E L++ N D + + K N EK E DK+ S R + +
Sbjct: 903 KEKHLMEKKNKQSDNSEYSKSEKGKNKEK--DRELDKKEKS----------RDKESINIT 950
Query: 363 NLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRS 422
N +K ++ + +K + +PLS L + K ++ + +
Sbjct: 951 N--SKHIQEEKKSSIVDGNKAQHEKPLSLKEK-TKDEPLKTPDGKEKDKKDKDIDRYKER 1007
Query: 423 DGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPER 482
D DK N S + + + P+ KS +D PK++ L +
Sbjct: 1008 DKHKDKIQIN------SLLKLKSEADKPKPKS-SPASKDTRPKEKRLVNDDLMQTSFERM 1060
Query: 483 ESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENED 542
S+ L +++ +K + IK + + L+++++ K K T T+ K
Sbjct: 1061 LSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKE------ 1114
Query: 543 QQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLNDL 602
+ +S V T K + R + + + + F D++L+ +
Sbjct: 1115 ------LTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPR 1168
Query: 603 VKNEKMG 609
+NEK G
Sbjct: 1169 SENEKPG 1175
Score = 40.8 bits (94), Expect = 0.006
Identities = 131/661 (19%), Positives = 244/661 (36%), Gaps = 90/661 (13%)
Query: 19 EERKEQTRNARAEVL--RQAKANFEKEERRKELKRLR-------GEDTWMLPDVNERI-- 67
E+RKE A L +Q KA + K + K+ K R D L N++I
Sbjct: 361 EQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQ--NKKIST 418
Query: 68 ------EQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVE 121
E + + KK+ K+ K K+K + K ++N E E+ +
Sbjct: 419 SCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRIT 478
Query: 122 AVPSQTPDKEKAWKVKDEK------SGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKE 175
+ T + + K ++E S KDDT + + K+ S +EK+
Sbjct: 479 NLTVNT-GLDCSEKTREEGNFRKSFSPKDDTSL------HLFHISTGKSPKHSCGLSEKQ 531
Query: 176 TMRKIEQEKNQALEQSKLMERELNP---YWKDGGTGLPPEDCSVSSI---TKVSVVEDGG 229
+ ++QE + E L P + + + PE SV S K +D
Sbjct: 532 S-TPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFH 590
Query: 230 LSWLRKSYLRMKEQAEKQSRNFEDIVAERYG----SMEIFQSKLEDAEKAASTKE-DYRR 284
L + KS ++K++ + D ++ +++ + K ++ EK KE + +
Sbjct: 591 LEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEK 650
Query: 285 ERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSL 344
E+++ D A+ Q S E D + + T D N +E ++K K ++
Sbjct: 651 EKYKT---KDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNI 707
Query: 345 ETCRRESNPRQNQEFSFGNLRAKFLRPSD--------------------DEELSFHSKGR 384
+ + ++E +F R K + S+ D++ F S G
Sbjct: 708 KDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGM 767
Query: 385 KFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQ 444
S LV + K K S+E+ S+ + +K + + +H+
Sbjct: 768 SAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHE 827
Query: 445 HVPEDPR---EKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVDE----KNKLG 497
H E + + D++ D H K G + + I D+ + K+
Sbjct: 828 HKSEKDKLDLSECVDKIKEKDKLYSHHTE--KCHKEGEKSKNTAAIKKTDDREKSREKMD 885
Query: 498 AKIIKAEMMGNMELAEQLKVQL-EKANKFKETITQIPKKSGVENEDQQEVILVRTDQSGR 556
K K + LAE + L EK NK + + G E +E L + ++S
Sbjct: 886 RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRE--LDKKEKSRD 943
Query: 557 VWPVN-TPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGTAENQN 615
+N T K ++ + +K +V ++ + + LSL + K+E + T + +
Sbjct: 944 KESINITNSKHIQEE---KKSSIVDGNKAQH-------EKPLSLKEKTKDEPLKTPDGKE 993
Query: 616 K 616
K
Sbjct: 994 K 994
Score = 40.4 bits (93), Expect = 0.007
Identities = 87/458 (18%), Positives = 177/458 (38%), Gaps = 64/458 (13%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANF--EKEERRKELKRLRGEDTWMLPDVNERIEQF 70
E K +E ++ R + + L++ + N +K+ L E++ L V + I+
Sbjct: 727 ERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIE 786
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEW-VEAVPSQTPD 129
QE +K+ K+K + + K++ +K +++ +EK + S +D+ + + +
Sbjct: 787 KQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKE 846
Query: 130 KEKAWKVKDEKSGKD-----DTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEK 184
K+K + EK K+ +T IK+ + K+ K +KE K E+E+
Sbjct: 847 KDKLYSHHTEKCHKEGEKSKNTAAIKKTD------DREKSREKMDRKHDKE---KPEKER 897
Query: 185 NQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQA 244
+ A + K + + N S ++ S E G + + ++
Sbjct: 898 HLAESKEKHLMEKKN---------------KQSDNSEYSKSEKGKNKEKDRELDKKEKSR 942
Query: 245 EKQS---RNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQE 301
+K+S N + I E+ S I EK S KE + E + P +K +
Sbjct: 943 DKESINITNSKHIQEEKKSS--IVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEK-----D 995
Query: 302 SRESDLVKYGNSSRDRYATTDTAKNS---NNEKFIGDEKDKRPGSLETCRRESNPRQNQE 358
++ D+ DRY D K+ N+ + E DK +++ P++ +
Sbjct: 996 KKDKDI--------DRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRL 1047
Query: 359 FSFGNLRAKFLRPSDDEELSFHSKGRKF-EPLSSSSALVAQGSLCSGFR---------KP 408
+ ++ F R ++L +K E + + C + P
Sbjct: 1048 VNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTP 1107
Query: 409 TKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHV 446
T++ + LT S+S D ++P + ++ Q V
Sbjct: 1108 TESKNKELTR-SKSSEVTDAYTKEKQPKDAVSNRSQSV 1144
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 57.0 bits (136), Expect = 8e-08
Identities = 120/600 (20%), Positives = 233/600 (38%), Gaps = 77/600 (12%)
Query: 41 EKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQ 100
EK + +K+ GE + + F KK K+ + K K K K+ +K+
Sbjct: 604 EKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKE 663
Query: 101 KYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGK-DDTQIIKRDEWMTVDF 159
K++K E ++D E S D+E WK KS + +D + E +T++
Sbjct: 664 KHKKEIEGEKEKYKTKDSAKELQRSVEFDRE-FWKENFFKSDETEDLFLNMEHESLTLE- 721
Query: 160 MSVKTVSSSSLKAEKETMRK-IEQEKNQALEQSKLMERELNPYWKDGGTGLPPE------ 212
K+ ++K +K T K + +E+N E+ K+ + + ++ L E
Sbjct: 722 --KKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPT 779
Query: 213 --DCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLE 270
D +S+ ++ E GL + K EKQ ++ ++ + +I + +E
Sbjct: 780 DKDSEFTSLGMSAIEESIGLHLVEKEI-----DIEKQEKHIKESKEKPEKRSQIKEKDIE 834
Query: 271 DAEKAASTKE-DYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNN 329
E+ KE + E + D ++ + +E D + Y + + + + +KN+
Sbjct: 835 KMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKL-YSHHTEKCHKEGEKSKNTAA 893
Query: 330 EKFIGDEKDKRPGSLETCRRESNPRQNQ---EFSFGNLRAKFLRPSDDEELSFHSKGRKF 386
K D+++K ++ + P + + E +L K + SD+ E S KG+
Sbjct: 894 IKKT-DDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNK 952
Query: 387 EPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHV 446
E K + ++ + S + KH ++ + D ++
Sbjct: 953 E-------------------KDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQ 993
Query: 447 PEDP---REKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVDEKNKLGAKIIKA 503
E P +EK++DE L+ K++ +D I E++K KI
Sbjct: 994 HEKPLSLKEKTKDEPLKTPDGKEKDKKDK-------------DIDRYKERDKHKDKIQIN 1040
Query: 504 EMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENEDQQEVILVRTDQSGRVWPVNTP 563
++ A++ K + A+K PK+ + N+D + R
Sbjct: 1041 SLLKLKSEADKPKPKSSPASKDTR-----PKEKRLVNDDLMQTSFERM----------LS 1085
Query: 564 GKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGTAENQNKLFMRMAS 623
K LE + +K + +E+ER+R + L + D K + T E++NK R S
Sbjct: 1086 LKDLEIEQWHKKHKEKIKQKEKERLRN-RNCLELKIKDKEKTKHTPT-ESKNKELTRSKS 1143
Score = 49.7 bits (117), Expect = 1e-05
Identities = 66/333 (19%), Positives = 132/333 (39%), Gaps = 45/333 (13%)
Query: 23 EQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKK 82
E+++N A K ++E+ R+++ R ++ P+ + + ++H ++KK K+
Sbjct: 886 EKSKNTAA-----IKKTDDREKSREKMDRKHDKEK---PEKERHLAESKEKHLMEKKNKQ 937
Query: 83 DKHSKKAKKEK-KKKSKKQKYEKNNESSDSSSSS--------EDEWVEAVPSQTPDKEKA 133
+S+ +K EK K K K ++ +K +S D S + E++ V EK
Sbjct: 938 SDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKP 997
Query: 134 WKVKDEKSGK-----DDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQAL 188
+K++ + D + K+D+ D K K + ++ K++ E ++
Sbjct: 998 LSLKEKTKDEPLKTPDGKEKDKKDK----DIDRYKERDKHKDKIQINSLLKLKSEADKPK 1053
Query: 189 EQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQS 248
+S ++ P K L +D +S ++ ++D + K + +Q EK
Sbjct: 1054 PKSSPASKDTRPKEK----RLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEK-- 1107
Query: 249 RNFEDIVAERYGSMEIFQSKLEDAEKAAST-KEDYRRERWRKPTYSDKAQNCQESRESDL 307
ER + + K++D EK T E +E R + +E + D
Sbjct: 1108 --------ERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDA 1159
Query: 308 VKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKR 340
V S+R + T F+ D R
Sbjct: 1160 V----SNRSQSVDTKNVMTLGKSSFVSDNSLNR 1188
Score = 46.2 bits (108), Expect = 1e-04
Identities = 113/607 (18%), Positives = 228/607 (37%), Gaps = 96/607 (15%)
Query: 19 EERKEQTRNARAEVLRQA-------KANFEKEERRKELKRLRGEDTWMLPDVNERIEQFS 71
E+ K +T+++ E+ R K NF K + ++L +N E +
Sbjct: 672 EKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDL------------FLNMEHESLT 719
Query: 72 QEHSVKKKKK-KDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDK 130
E K +K KD S K K K+++ K++ +K + S+ S E
Sbjct: 720 LEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREE-------------- 765
Query: 131 EKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKT-----VSSSSLKAEKETMRKIEQEKN 185
K+KD K +++ K E+ ++ +++ + + EK+ + I++ K
Sbjct: 766 ----KIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQE-KHIKESKE 820
Query: 186 QALEQSKLMERELNPYWK---DGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKE 242
+ ++S++ E+++ + + + E S +S D ++KE
Sbjct: 821 KPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVD-----------KIKE 869
Query: 243 QAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQES 302
+ + S + E E S K D + + K D + ++ KP +K ++ ES
Sbjct: 870 KDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDK-EKP---EKERHLAES 925
Query: 303 RESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFG 362
+E L++ N D + + K N EK E DK+ S R + +
Sbjct: 926 KEKHLMEKKNKQSDNSEYSKSEKGKNKEK--DRELDKKEKS----------RDKESINIT 973
Query: 363 NLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRS 422
N +K ++ + +K + +PLS L + K ++ + +
Sbjct: 974 N--SKHIQEEKKSSIVDGNKAQHEKPLSLKEK-TKDEPLKTPDGKEKDKKDKDIDRYKER 1030
Query: 423 DGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPER 482
D DK N S + + + P+ KS +D PK++ L +
Sbjct: 1031 DKHKDKIQIN------SLLKLKSEADKPKPKS-SPASKDTRPKEKRLVNDDLMQTSFERM 1083
Query: 483 ESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENED 542
S+ L +++ +K + IK + + L+++++ K K T T+ K
Sbjct: 1084 LSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKE------ 1137
Query: 543 QQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLNDL 602
+ +S V T K + R + + + + F D++L+ +
Sbjct: 1138 ------LTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPR 1191
Query: 603 VKNEKMG 609
+NEK G
Sbjct: 1192 SENEKPG 1198
Score = 40.8 bits (94), Expect = 0.006
Identities = 131/661 (19%), Positives = 244/661 (36%), Gaps = 90/661 (13%)
Query: 19 EERKEQTRNARAEVL--RQAKANFEKEERRKELKRLR-------GEDTWMLPDVNERI-- 67
E+RKE A L +Q KA + K + K+ K R D L N++I
Sbjct: 384 EQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQ--NKKIST 441
Query: 68 ------EQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVE 121
E + + KK+ K+ K K+K + K ++N E E+ +
Sbjct: 442 SCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRIT 501
Query: 122 AVPSQTPDKEKAWKVKDEK------SGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKE 175
+ T + + K ++E S KDDT + + K+ S +EK+
Sbjct: 502 NLTVNT-GLDCSEKTREEGNFRKSFSPKDDTSL------HLFHISTGKSPKHSCGLSEKQ 554
Query: 176 TMRKIEQEKNQALEQSKLMERELNP---YWKDGGTGLPPEDCSVSSI---TKVSVVEDGG 229
+ ++QE + E L P + + + PE SV S K +D
Sbjct: 555 S-TPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFH 613
Query: 230 LSWLRKSYLRMKEQAEKQSRNFEDIVAERYG----SMEIFQSKLEDAEKAASTKE-DYRR 284
L + KS ++K++ + D ++ +++ + K ++ EK KE + +
Sbjct: 614 LEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEK 673
Query: 285 ERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSL 344
E+++ D A+ Q S E D + + T D N +E ++K K ++
Sbjct: 674 EKYKT---KDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNI 730
Query: 345 ETCRRESNPRQNQEFSFGNLRAKFLRPSD--------------------DEELSFHSKGR 384
+ + ++E +F R K + S+ D++ F S G
Sbjct: 731 KDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGM 790
Query: 385 KFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQ 444
S LV + K K S+E+ S+ + +K + + +H+
Sbjct: 791 SAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHE 850
Query: 445 HVPEDPR---EKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVDE----KNKLG 497
H E + + D++ D H K G + + I D+ + K+
Sbjct: 851 HKSEKDKLDLSECVDKIKEKDKLYSHHTE--KCHKEGEKSKNTAAIKKTDDREKSREKMD 908
Query: 498 AKIIKAEMMGNMELAEQLKVQL-EKANKFKETITQIPKKSGVENEDQQEVILVRTDQSGR 556
K K + LAE + L EK NK + + G E +E L + ++S
Sbjct: 909 RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRE--LDKKEKSRD 966
Query: 557 VWPVN-TPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGTAENQN 615
+N T K ++ + +K +V ++ + + LSL + K+E + T + +
Sbjct: 967 KESINITNSKHIQEE---KKSSIVDGNKAQH-------EKPLSLKEKTKDEPLKTPDGKE 1016
Query: 616 K 616
K
Sbjct: 1017 K 1017
Score = 40.4 bits (93), Expect = 0.007
Identities = 87/458 (18%), Positives = 177/458 (38%), Gaps = 64/458 (13%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANF--EKEERRKELKRLRGEDTWMLPDVNERIEQF 70
E K +E ++ R + + L++ + N +K+ L E++ L V + I+
Sbjct: 750 ERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIE 809
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEW-VEAVPSQTPD 129
QE +K+ K+K + + K++ +K +++ +EK + S +D+ + + +
Sbjct: 810 KQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKE 869
Query: 130 KEKAWKVKDEKSGKD-----DTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEK 184
K+K + EK K+ +T IK+ + K+ K +KE K E+E+
Sbjct: 870 KDKLYSHHTEKCHKEGEKSKNTAAIKKTD------DREKSREKMDRKHDKE---KPEKER 920
Query: 185 NQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQA 244
+ A + K + + N S ++ S E G + + ++
Sbjct: 921 HLAESKEKHLMEKKN---------------KQSDNSEYSKSEKGKNKEKDRELDKKEKSR 965
Query: 245 EKQS---RNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQE 301
+K+S N + I E+ S I EK S KE + E + P +K +
Sbjct: 966 DKESINITNSKHIQEEKKSS--IVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEK-----D 1018
Query: 302 SRESDLVKYGNSSRDRYATTDTAKNS---NNEKFIGDEKDKRPGSLETCRRESNPRQNQE 358
++ D+ DRY D K+ N+ + E DK +++ P++ +
Sbjct: 1019 KKDKDI--------DRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRL 1070
Query: 359 FSFGNLRAKFLRPSDDEELSFHSKGRKF-EPLSSSSALVAQGSLCSGFR---------KP 408
+ ++ F R ++L +K E + + C + P
Sbjct: 1071 VNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTP 1130
Query: 409 TKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHV 446
T++ + LT S+S D ++P + ++ Q V
Sbjct: 1131 TESKNKELTR-SKSSEVTDAYTKEKQPKDAVSNRSQSV 1167
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 57.0 bits (136), Expect = 8e-08
Identities = 116/572 (20%), Positives = 213/572 (37%), Gaps = 80/572 (13%)
Query: 72 QEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKE 131
QE S +K K DK KK +K + KK+K EK + D S SED Q +KE
Sbjct: 309 QESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKE 368
Query: 132 -KAWKVKDEKSG---------KDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIE 181
++ K+ EK+ K+D +I D D ++V +V +S L + +E + E
Sbjct: 369 VESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTD-ITVSSVHTSDLSSFEEDTEE-E 426
Query: 182 QEKNQALEQSKLM--ERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLR 239
+ ++E+ ++ + E N K T D S V +++ K YL
Sbjct: 427 VVTSDSMEEGEITSDDEEKN---KQNKTKTQTSDSSEGKTKSVR------HAYVHKPYLY 477
Query: 240 MKEQA--------EKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPT 291
K + E++ ++ ER +I + KLE+ K + K + + + +
Sbjct: 478 SKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRS 537
Query: 292 YSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRES 351
D ++ +S E + ++R S K KD R E
Sbjct: 538 SVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRK-----KDSR-------NVEE 585
Query: 352 NPRQNQEFSFGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKN 411
N ++ Q++ D +E S+ + E +SSS L S KP +
Sbjct: 586 NSKKKQQYE-----------EDSKETLKTSEHCEKEKISSSKEL-KHVHAKSEPSKPARR 633
Query: 412 SEERL--TSWSRSDGRGDKKHSNQKPSET---STDEHQHVPEDPREKSQDEVLRDDPPKK 466
E L ++++ + +++H + + E + R+ + E+ ++P K+
Sbjct: 634 LSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQ 693
Query: 467 EHLRDTKSTFAGSPERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFK 526
KST + H+ D + ++K E+ + E E+ K E K
Sbjct: 694 ------KSTL-----KNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVK 742
Query: 527 ETIT-QIPKKSGVENEDQQEVILVRTDQSGRVWPVNTPGKSLESQ-GGRRKRQMVSTHEE 584
K+G E E + + + G N +S +++ K + S H
Sbjct: 743 HKYKGDCMHKTGDETE-------LHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRN 795
Query: 585 RERVRYFHDDDNLSLNDLVKNEKMGTAENQNK 616
++ D ++K ++ EN K
Sbjct: 796 ERKLSVLGKDGKPVSEYIIKTDENVRKENNKK 827
Score = 37.7 bits (86), Expect = 0.048
Identities = 67/313 (21%), Positives = 120/313 (38%), Gaps = 24/313 (7%)
Query: 31 EVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKAK 90
E L + F E +GE + D E I S E K+ +++++H K K
Sbjct: 2713 ESLNVENSGFRTNEEIHSESYNKGEISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRK 2772
Query: 91 KEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIK 150
+KQ Y + + D + D +E Q P+ E K+E S +D ++ K
Sbjct: 2773 -------RKQHYLSSEDEPDDNPDVLDSRIETAQRQCPETE-PHDTKEENS-RDLEELPK 2823
Query: 151 ---RDEWMTVDFMSVK-TVSSSSLKAEKETMRKIEQEKNQALEQSKLMEREL-NPYWKDG 205
T M K SSS EK + K+Q +Q +++R+ P
Sbjct: 2824 TSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPV 2883
Query: 206 GTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFED-IVAERYGSMEI 264
T L +D S + V+V + S L+ + +++ K++ N ++ ++ G +I
Sbjct: 2884 ETTLKMKDDSKTDTGIVTVEQSPSSSKLK---VMQTDESNKETANLQERSISNDDGEEKI 2940
Query: 265 FQSKLEDAEK------AASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRY 318
S K + E ER R+ + SD ++ +E + +
Sbjct: 2941 VTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSG 3000
Query: 319 ATTDTAKNSNNEK 331
ATT + S ++
Sbjct: 3001 ATTRSTTRSEAQR 3013
Score = 33.5 bits (75), Expect = 0.91
Identities = 33/173 (19%), Positives = 79/173 (45%), Gaps = 10/173 (5%)
Query: 34 RQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEK 93
R+ K+ E++ K + +G+ + V +++ + + + K K+K++++ EK
Sbjct: 898 RRTKSLLEEKLVLKSKSKTQGKQVKV---VETELQEGATKQATTPKPDKEKNTEENDSEK 954
Query: 94 KKKSK--KQKYEKNN-----ESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDT 146
++KSK + +E+ E++ SS+ S + KEK KD S + +
Sbjct: 955 QRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLER 1014
Query: 147 QIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLMERELN 199
++ + ++ S K++ + ++++ +A S LME++L+
Sbjct: 1015 KLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLS 1067
>gi|42718020 retinitis pigmentosa 9 [Homo sapiens]
Length = 221
Score = 57.0 bits (136), Expect = 8e-08
Identities = 33/96 (34%), Positives = 57/96 (59%), Gaps = 3/96 (3%)
Query: 16 KSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHS 75
+ +E+ + + +++R K + EK+ R ++LK+L + T + + ++H
Sbjct: 128 QKLEQFRVAHEDPMYDIIRDNKRH-EKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKH- 185
Query: 76 VKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDS 111
KKKKKK+KH K+ K++KKKK +K K K+NE SDS
Sbjct: 186 -KKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDS 220
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 56.6 bits (135), Expect = 1e-07
Identities = 92/527 (17%), Positives = 210/527 (39%), Gaps = 66/527 (12%)
Query: 7 AASGRFESAKSIEERKEQTRNARAEVLRQAKANF-------EKEERRKELKRLRGEDTWM 59
A S + E +++E K + A+ +L Q + N ++EE R++ K++R ++ M
Sbjct: 199 AESEKSEIQLNVKELKRKLERAKF-LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 257
Query: 60 LPDVNERIEQFS----QEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSS 115
EQ QE +++++K+ + +K +E++K+ ++QK K E +
Sbjct: 258 WRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK--KLREQEEQMQEQ 315
Query: 116 EDEWVEAVPSQTPDKEKAWKV--------------------KDEKSGKDDTQIIKRDE-- 153
E++ E +EK W+ ++E+ + D ++ +++E
Sbjct: 316 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 375
Query: 154 ------WMTVDFMSVK---TVSSSSLKAEKETMRKIEQEKNQALEQSKLMERELNPYWKD 204
W + M + ++ E+ETMR EQE+ ++ + E+E W+
Sbjct: 376 REQEKMWEQEEKMQEEERIREREKKMREEEETMR--EQEEKMQKQEENMWEQE-EKEWQQ 432
Query: 205 GGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNF--EDIVAERYGSM 262
LP + + K+ E+ W ++ +R +E+ Q + ++ + E+ M
Sbjct: 433 --QRLPEQKEKLWEQEKMQEQEE--KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 488
Query: 263 EIFQSKLEDAEKAASTKED---YRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYA 319
+ K+ D E+ +E+ + ER R+ + Q +E + + +
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548
Query: 320 TTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRAKFLRPSD---DEE 376
T D + E+ + + + K E R + Q QE K + ++E
Sbjct: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608
Query: 377 LSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPS 436
+ K + Q + + + EE++ W + + +++ ++
Sbjct: 609 EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM--WEQEEKMREQEEKMREQE 666
Query: 437 ETSTDEHQHVPE-DPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPER 482
E + + + E + + + Q+E +R+ ++E +R + G E+
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMRE---QEEKMRGQEEKMWGQEEK 710
Score = 55.5 bits (132), Expect = 2e-07
Identities = 69/371 (18%), Positives = 156/371 (42%), Gaps = 44/371 (11%)
Query: 11 RFESAKSIEER------KEQTRNARAEVLRQAKAN-FEKEERRKELKRL--RGEDTWMLP 61
+ + + I ER +E+T + E +++ + N +E+EE+ + +RL + E W
Sbjct: 387 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446
Query: 62 DVNERIEQ-FSQEHSVKKKKKKDKHSKKA-KKEKKKKSKKQKYEKNNESSDSSSS----- 114
+ E+ E+ + QE ++ +++ KK ++EK ++ + Q +E+ + D
Sbjct: 447 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
Query: 115 ----SEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVK---TVSS 167
+DE + + +++K W+ +++ + TQ ++ W + M +
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566
Query: 168 SSLKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVED 227
++ E+E MR EQE+ ++ K+ E+E W+ + + E
Sbjct: 567 KKMREEEEMMR--EQEEKMQEQEEKMREQE-EKMWEQ----------------EEKMQEQ 607
Query: 228 GGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERW 287
W ++ + +E+ +K E+++ E+ M+ + K+ + E+ +E+ RE+
Sbjct: 608 EEKMWEQEEKMWEQEEEDKMQEQ-EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666
Query: 288 RKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETC 347
K ++ QE + + ++ + EK G E +K G E
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQE-EKMWGQEEMR 725
Query: 348 RRESNPRQNQE 358
+E R +E
Sbjct: 726 EKEERIRDQKE 736
Score = 53.1 bits (126), Expect = 1e-06
Identities = 92/533 (17%), Positives = 208/533 (39%), Gaps = 56/533 (10%)
Query: 23 EQTRNARAEVLRQAK-ANFEKEERR---KELKRLRGEDTWMLPDVNERI---EQFSQEHS 75
E+ + AE+ + + A EK E + KELKR ++LP V E + QE
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 76 VKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWK 135
+++++KK + K+ +K +++ + ++ E + +++ + + ++EK +
Sbjct: 243 LREQEKKIR--KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
Query: 136 VKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLME 195
+ +K + + Q+ +++E M + + + K ++ R EQEK ++ K+ +
Sbjct: 301 -EQKKLREQEEQMQEQEEKM---WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
Query: 196 RELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQ----AEKQSRNF 251
+E + +D LR+ RM+EQ +++
Sbjct: 357 QEERMWEQD--------------------------ERLREKEERMREQEKMWEQEEKMQE 390
Query: 252 EDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYG 311
E+ + ER M + + + E+ +E+ W + + Q E +E +
Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEE---NMWEQEEKEWQQQRLPEQKEKLWEQEK 447
Query: 312 NSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRAKFLRP 371
++ K + E+ G E K+ E R + + QE +R + +
Sbjct: 448 MQEQEEKIWEQEEKIRDQEEMWGQE--KKMWRQEKMREQEDQMWEQE---EKMRDQEQKM 502
Query: 372 SDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHS 431
D EE + R E R+ K E+ +W + + +++
Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 432 NQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVD 491
++ + +E ++ + + Q+E +R+ K + + + +
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Query: 492 EKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENEDQQ 544
E++K+ + EMM E E+++ Q EK + +E + + +K + E Q
Sbjct: 623 EEDKMQE---QEEMMWEQE--EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 56.6 bits (135), Expect = 1e-07
Identities = 70/354 (19%), Positives = 150/354 (42%), Gaps = 29/354 (8%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQ--F 70
E + I E++E+ R ++ RQ + +EKEE+ R + E W + R E+ +
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK----MRRQEEMMWEKEEKMRRQEEMMW 434
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQK---YEKNNESSDSSSSSEDEWVEAVPSQT 127
+E +++ ++K +K +++++K+ +++K EK E E++ E
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 128 PDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQ---EK 184
+EK W+ ++EK + + I+ +E K + ++E +R+ E+ +K
Sbjct: 495 EQEEKMWR-QEEKIHEQEK--IREEE---------KRQEQEEMWRQEEKIREQEEIWRQK 542
Query: 185 NQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQA 244
+ EQ + + ++ W+ E+ KV E+ +R+ +++EQ
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEK----IREQEEKIREQE 598
Query: 245 EKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRE 304
EK R E++ E+ M + K+ + E+ +E+ R + K +K QE +
Sbjct: 599 EK-IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657
Query: 305 SDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQE 358
+ + ++ + EK E+ R + +E RQ +E
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 711
Score = 52.0 bits (123), Expect = 2e-06
Identities = 60/307 (19%), Positives = 140/307 (45%), Gaps = 22/307 (7%)
Query: 12 FESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKEL-------KRLRGEDTWMLPDVN 64
+E + + ++E ++ RQ + +EKEE+ +EL +++R ++ +
Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 465
Query: 65 ERIEQFSQEHSVK----KKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV 120
R ++ QE K ++K +++ K ++E+K +++K + + + E E +
Sbjct: 466 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEM 525
Query: 121 EAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDE--WMTVDFM--SVKTVSSSSLKAEKET 176
+ ++E+ W+ K EK + + +I K++E W + M + + K ++
Sbjct: 526 WRQEEKIREQEEIWRQK-EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQE 584
Query: 177 MRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKS 236
+ EQE+ ++ K+ E+E ++ G E+ K+ E+ +R+
Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEEKMG-EQEEKMCEQEEKMQEQEEK----MRRQ 639
Query: 237 YLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKA 296
+++EQ EK+ R E+ + E+ M+ + K+ + E+ +E+ +E+ K ++
Sbjct: 640 EEKIREQ-EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698
Query: 297 QNCQESR 303
QE R
Sbjct: 699 MWEQEVR 705
Score = 37.4 bits (85), Expect = 0.063
Identities = 54/330 (16%), Positives = 129/330 (39%), Gaps = 8/330 (2%)
Query: 32 VLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKAKK 91
V + +A E+ E L + + E W + + E+ QE K +++++K ++ +K
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Query: 92 EKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDD---TQI 148
++++ + E+ + ++E + +KE+ + +EK + + Q
Sbjct: 398 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 457
Query: 149 IKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTG 208
KR E + + + + ++E +R EQE+ ++ K+ +E + ++
Sbjct: 458 EKRQEEEKIREQEKRQEQEAKMWRQEEKIR--EQEEKIREQEEKMWRQEEKIHEQEKIRE 515
Query: 209 LPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSK 268
+ + + W +K ++ EQ EK R E+ + + M + K
Sbjct: 516 EEKRQEQEEMWRQEEKIREQEEIWRQKE--KIHEQEEK-IRKQEEKMWRQEEKMHDQEEK 572
Query: 269 LEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSN 328
+ + E+ +E+ RE+ K ++ QE + + ++ +
Sbjct: 573 IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 632
Query: 329 NEKFIGDEKDKRPGSLETCRRESNPRQNQE 358
EK E+ R + +E R+ +E
Sbjct: 633 EEKMRRQEEKIREQEKKIREQEEKIREQEE 662
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 56.2 bits (134), Expect = 1e-07
Identities = 66/357 (18%), Positives = 152/357 (42%), Gaps = 38/357 (10%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
E + I E++E+ R ++ RQ + +EKEE+ R + E W + R+E+
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK----MRRQEEMMWEKEEKMRRLEEMMW 373
Query: 73 EHSVKKKKKKDKHSKKAK----KEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTP 128
E K ++ ++K ++ K +EK+++ +K + ++ + ++ ++E + +
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 129 DKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQ---EKN 185
++EK ++EK + + I+ +E K + ++E +R+ E+ +K
Sbjct: 434 EQEKKMWRQEEKIHEQEK--IREEE---------KRQEQEEMWRQEEKIREQEEIWRQKE 482
Query: 186 QALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKE--- 242
+ EQ K+ ++E W+ E+ + E W ++ +R +E
Sbjct: 483 KMHEQEKIRKQE-EKVWRQEEKMHDQEE---------KIREQEEKMWRQEEKIREQEEKI 532
Query: 243 -QAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQE 301
+ E++ R E+++ E+ M + K+++ EK +E R + + +K + +E
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
Query: 302 SRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQE 358
K ++ K E+ + ++++K E RR+ QE
Sbjct: 593 KIWEQEEKI--REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 647
Score = 48.1 bits (113), Expect = 4e-05
Identities = 63/327 (19%), Positives = 141/327 (43%), Gaps = 38/327 (11%)
Query: 12 FESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKEL-------KRLRGEDTWMLPDVN 64
+E + + ++E ++ R + +EKEE+ +EL +++R ++ +
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 404
Query: 65 ERIEQFSQEHSVK----KKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV 120
R ++ QE K ++K +++ K ++EKK +++K + + + E E +
Sbjct: 405 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 464
Query: 121 EAVPSQTPDKEKAWKVKD-----EKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAE-- 173
+ ++E+ W+ K+ EK K + ++ +++E M ++ + E
Sbjct: 465 WRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEK 524
Query: 174 -KETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSW 232
+E KI +++ + EQ ++M+ E + + ++ K+ E+
Sbjct: 525 IREQEEKIREQEEKIREQEEMMQ-EQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK---- 579
Query: 233 LRKSYLRMKEQAEK------QSRNFEDIVAERYGSMEIFQSKL-EDAEKAASTKEDYRRE 285
+R+ +++EQ EK + R E+++ E+ M + K+ E EK +E RR+
Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 286 R---W----RKPTYSDKAQNCQESRES 305
W R +K Q QE E+
Sbjct: 640 EEKMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 38.5 bits (88), Expect = 0.028
Identities = 56/331 (16%), Positives = 131/331 (39%), Gaps = 13/331 (3%)
Query: 32 VLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKAKK 91
V + +A E+ E L + + E W + + E+ QE K +++++K ++ +K
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 92 EKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDD---TQI 148
++++ + E+ + ++E + + +KE+ + +EK + + Q
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQE 396
Query: 149 IKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTG 208
KR E + + + + ++E +R EQE+ ++ K+ +E + ++
Sbjct: 397 EKRQEEEKIREQEKRQEQEAKMWRQEEKIR--EQEEKIREQEKKMWRQEEKIHEQEKIRE 454
Query: 209 LPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSK 268
+ + + W +K + +E+ KQ E+ V + M + K
Sbjct: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ----EEKVWRQEEKMHDQEEK 510
Query: 269 LEDAEKAASTKEDYRRERWRK-PTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNS 327
+ + E+ +E+ RE+ K +K + +E + K G + K
Sbjct: 511 IREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE---KMQEQEKMR 567
Query: 328 NNEKFIGDEKDKRPGSLETCRRESNPRQNQE 358
E+ I ++++K E R + QE
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
Score = 34.7 bits (78), Expect = 0.41
Identities = 21/97 (21%), Positives = 51/97 (52%), Gaps = 4/97 (4%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
E + I E+KE+ R ++ Q + E+EE +E + E W + E+ Q
Sbjct: 575 EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQE----QEEKMWEQEEKMCEQEEKMQ 630
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESS 109
E K +++++K ++ + ++++ K Q+++++ E++
Sbjct: 631 EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 56.2 bits (134), Expect = 1e-07
Identities = 71/331 (21%), Positives = 136/331 (41%), Gaps = 30/331 (9%)
Query: 62 DVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDS-SSSSEDEWV 120
D + ++ S S K K K SKK KK KK KK+ +K+ ES+D+ S S+DE
Sbjct: 287 DTKKNAKKSSDAESEDSKDAK-KDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDE-- 343
Query: 121 EAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKI 180
+ K+ K+K + KD + + + + D + S + KA K +K
Sbjct: 344 -----RKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKK 398
Query: 181 EQEK------NQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLR 234
+ +K +++ +SK +++ KD T + T G +
Sbjct: 399 DAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGK 458
Query: 235 KSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSD 294
K + K+ ++K + + A++ +S LE K+D + + +K + D
Sbjct: 459 KDEKKGKKDSKKDDKKKD---AKKNAESTEMESDLE-------LKKDKKHSKEKKGSKKD 508
Query: 295 KAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPR 354
++ ++ ES ++ SS+ + T+ K S+ E +E +PG+ +
Sbjct: 509 IKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTE---SEESLYKPGAKKKIDESDGTS 565
Query: 355 QNQEFSFGNLRAKFLRPSDDEELSFHSKGRK 385
N + L +K ++ +F+ KG K
Sbjct: 566 ANSKME--GLESKRGFRMSSKKTTFNEKGEK 594
Score = 52.4 bits (124), Expect = 2e-06
Identities = 120/529 (22%), Positives = 210/529 (39%), Gaps = 74/529 (13%)
Query: 78 KKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVK 137
KK K +K KK+ KKK Y N ES EA +TP K +
Sbjct: 116 KKSKDEKGGTPLKKDSKKKGGS--YATNPESKQIVEEKTKRQNEA--DKTPLKSSHENEQ 171
Query: 138 DEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLMERE 197
+KS K + + KTVS + + +K+ + ++ + L +++
Sbjct: 172 SKKS--------KSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKD 223
Query: 198 LNPYWKDGGTGLPP--EDCSVSSITK-----VSVVEDGGLS---WLRKSYLRMKEQAEKQ 247
L K T P E CS +S+ V +D ++ WLR ++
Sbjct: 224 L----KRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRN-------YSQNN 272
Query: 248 SRNFEDIVAERYGSMEIFQS--KLEDAEKAAS--TKEDYRRERWRKPTYSDKAQNCQESR 303
S+N+ + +Y + ++ K DAE S K+D ++ + + DK ++ ++
Sbjct: 273 SKNYS-LKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVK-KNVKKDDKKKDVKKDT 330
Query: 304 ESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKD--KRPGSLETCRRESNPRQNQEFSF 361
ES + G+S +R DT K+ K +KD K P S +T ++ +N +
Sbjct: 331 ESTDAESGDSKDER---KDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNL 387
Query: 362 GNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSR 421
+ D ++++F + S S L + K ++ E++ +
Sbjct: 388 KKASKNDDKKKDAKKITFST--------DSESELES---------KESQKDEKK----DK 426
Query: 422 SDGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPE 481
D + D K S K E STD D ++ +DE KK+ + A S E
Sbjct: 427 KDSKTDNKKS-VKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTE 485
Query: 482 RESIHILSVDEKNKLGAKIIKAEMMGNMEL-AEQLKVQLEKANK--FKETITQIPKKSGV 538
ES L D+K+ K K ++ + E + ++++K FK T T+I K S
Sbjct: 486 MESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFK-TSTKI-KGSDT 543
Query: 539 ENEDQ--QEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEER 585
E+E+ + + D+S N+ + LES+ G R +T E+
Sbjct: 544 ESEESLYKPGAKKKIDESDGT-SANSKMEGLESKRGFRMSSKKTTFNEK 591
Score = 45.8 bits (107), Expect = 2e-04
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 28/202 (13%)
Query: 16 KSIEERKEQTRNARAEVLRQAKANFEKEERRKELKR-LRGEDTWMLPDVNERIEQFSQEH 74
KS + E +++A+ + ++ K N +K++++K++K+ D +ER + +
Sbjct: 294 KSSDAESEDSKDAKKDS-KKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKK 352
Query: 75 SVKK-KKKKD---------------KHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDE 118
+KK KKKD K ++ + KK SK +K+ + S+ SE E
Sbjct: 353 KLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESE 412
Query: 119 WVEAVPSQTPDKEKAWKVKDEKSGK-DDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETM 177
+E+ SQ +K KD+K K D+ + +K DE T K S K EK+
Sbjct: 413 -LESKESQKDEK------KDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGK 465
Query: 178 R--KIEQEKNQALEQSKLMERE 197
+ K + +K A + ++ E E
Sbjct: 466 KDSKKDDKKKDAKKNAESTEME 487
Score = 38.9 bits (89), Expect = 0.022
Identities = 30/123 (24%), Positives = 57/123 (46%), Gaps = 13/123 (10%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
ES + E K ++ + + ++ K + +K++++K+ K+ E T M D+
Sbjct: 442 ESTDADSEPKGDSKKGKKDE-KKGKKDSKKDDKKKDAKK-NAESTEMESDLE-------- 491
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEK 132
+KK KK K K +KK+ KK ++K + E +SS + + S T +E
Sbjct: 492 ---LKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEES 548
Query: 133 AWK 135
+K
Sbjct: 549 LYK 551
Score = 37.4 bits (85), Expect = 0.063
Identities = 36/146 (24%), Positives = 57/146 (39%), Gaps = 7/146 (4%)
Query: 42 KEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQK 101
KE ++ E K + T V E + K KK K +K K+ KK K+K
Sbjct: 416 KESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKK 475
Query: 102 YEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKD-EKSGKDDTQI--IKRDEWMTVD 158
K N S S +E + KEK KD +K + DT+ + DE
Sbjct: 476 DAKKNAESTEMESD----LELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTG 531
Query: 159 FMSVKTVSSSSLKAEKETMRKIEQEK 184
F + + S ++E+ + ++K
Sbjct: 532 FKTSTKIKGSDTESEESLYKPGAKKK 557
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 55.8 bits (133), Expect = 2e-07
Identities = 129/708 (18%), Positives = 288/708 (40%), Gaps = 81/708 (11%)
Query: 7 AASGRFESAKSIEERKEQTRNARAEVLRQAKANF-------EKEERRKELKRLRGEDTWM 59
A S + E +++E K + A+ +L Q + N ++EE R++ K++R ++ M
Sbjct: 237 AESEKSEIQLNVKELKRKLERAKF-LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 295
Query: 60 LPDVNERIEQFS----QEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSS 115
EQ QE + +++K+ + +K +E++K+ ++QK + E +
Sbjct: 296 WRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK--ELREQEEQMQEQ 353
Query: 116 EDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKE 175
E++ E +EK W+ ++E+ + + Q+ ++++ M D L+ ++E
Sbjct: 354 EEKMWEQEEKMREQEEKMWR-QEERLWEQEKQMREQEQKMR-DQEERMWEQDERLREKEE 411
Query: 176 TMR---KIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSW 232
MR K+ ++ + E+ K+ E+E +D + E+ K+ E+
Sbjct: 412 RMREQEKMWEQVEKMREEKKMQEQEKKT--RDQEEKMQEEERIREREKKMREEEETMREQ 469
Query: 233 ---LRKSYLRMKEQAEKQSR-----NFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRR 284
++K M EQ EK+ + ++ + E+ E + E EK +E + +
Sbjct: 470 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 529
Query: 285 ER--WRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTD--TAKNSNNEKFIGDEKDKR 340
E+ WR+ ++ E E K + + + + K EK D+++K
Sbjct: 530 EKKMWRQEKMREQEDQMWEQEE----KMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM 585
Query: 341 PGSLETCRRESNPRQNQEFSFGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGS 400
RE R+ +E +R + + + EE + + +E
Sbjct: 586 REEERMREREKKMREEEEM----MREQEEKMQEQEEKMQEQEEKMWEQEEKMQ------- 634
Query: 401 LCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHVPEDPREKSQDE-VL 459
+ K E+ W + + +++ ++ + EH+ + E + + Q+E +
Sbjct: 635 -----EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW--EHEKMQEQEKMQEQEEKIW 687
Query: 460 RDDPPKKEHLRDTKSTFAGSPERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQL 519
+ +K+ K T+ RE + ++K + + EMM E E+++ Q
Sbjct: 688 EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR-----EEEEMMREQE--EKMQEQE 740
Query: 520 EKANKFKETITQIPKKSGVENE---DQQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKR 576
EK + +E + + +K + E +QQ + +Q ++W K E + +
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEEKMWEQQRL----PEQKEKLWEHE---KMQEQEKIWEQE 793
Query: 577 QMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGTAENQNKLFMRMASKFMGKTDGDYYTL 636
+ + EE+ R + ++ + ++ ++ + K++ K G+ + +
Sbjct: 794 EKMRDQEEKMRGQ---EEKMRGQEEKMRGQEEKMWGQEEKMW-GQEEKMWGQEEKMWGQE 849
Query: 637 DDMFVSKAAERERLGEEEE---NQRKKAIAEHRSLAAQMEKCLYCFDS 681
+ M + E++ E+EE Q +K + + Q EK +YC S
Sbjct: 850 EKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK-IYCVGS 896
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 55.5 bits (132), Expect = 2e-07
Identities = 84/408 (20%), Positives = 148/408 (36%), Gaps = 63/408 (15%)
Query: 79 KKKKDKHSKKAKKEKKKK-SKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKA---W 134
K++ HS+ + KE+ + S + E S S + D P++ D+ ++ +
Sbjct: 361 KERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPY 420
Query: 135 KVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLM 194
K +D + + RD S S K R + N+A + S+
Sbjct: 421 KARDRSRSRSPNKA--RD-------------CSRSRSPYKARDRSRSRSPNKARDHSR-- 463
Query: 195 ERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDI 254
R N + P ++ S + S D R+S KE+ +QSR+
Sbjct: 464 SRSPNKARDRSRSRSPSKERDHSQLGSPSKERDH-----RRSRSPSKERQCRQSRS---- 514
Query: 255 VAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYS---DKAQNCQESRESDLVKYG 311
SK D ++ S ++ +R + R P ++++ E RE +
Sbjct: 515 -----------SSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSP 563
Query: 312 NSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRAKFLRP 371
+ RDR +K E+++R R S R + N ++ + RP
Sbjct: 564 SKERDRRRWRSPSK----------ERERRQS-----RSSSEERDHSRSRSPNKQSGYSRP 608
Query: 372 SDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHS 431
+ HS+ R S +Q S P++++ R W RS R
Sbjct: 609 RASSKEKAHSRSRT----PSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQ 664
Query: 432 NQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGS 479
N+ PS+TS+ P + SQD+ D K L +S+ + S
Sbjct: 665 NRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
Score = 31.6 bits (70), Expect = 3.4
Identities = 14/55 (25%), Positives = 28/55 (50%)
Query: 78 KKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEK 132
+ K++ ++++ K++ ++Q N E S S S E E S++P KE+
Sbjct: 513 RSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKER 567
Score = 30.8 bits (68), Expect = 5.9
Identities = 28/134 (20%), Positives = 56/134 (41%), Gaps = 11/134 (8%)
Query: 11 RFESAKSIEERKEQTRNARAEVLR-QAKANFEKEERRKELKRLRGEDT--WMLPDVNERI 67
R + S E ++ Q+R+ E R Q+++ E+ E R+ + D W P
Sbjct: 522 RRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERER 581
Query: 68 EQF-----SQEHSVKKKKKKD---KHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEW 119
Q ++HS + K + + KEK + ++ N S +SS E +
Sbjct: 582 RQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDP 641
Query: 120 VEAVPSQTPDKEKA 133
++ ++PD +++
Sbjct: 642 SQSTVPRSPDWKRS 655
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 55.5 bits (132), Expect = 2e-07
Identities = 116/614 (18%), Positives = 229/614 (37%), Gaps = 54/614 (8%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
+ +K E E R + EV Q E+E R L+ LR + NE++E+ S
Sbjct: 615 QKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQH-------NEKVEENST 667
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEK 132
++ + + + + K ++Q + + D S DE A S+ D+EK
Sbjct: 668 LQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSE--DREK 725
Query: 133 AWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLK-AEKETMRKIEQEKNQALEQS 191
+++ K D Q + + D + + ++LK A KE + +QE ++ EQ
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQY 785
Query: 192 KLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNF 251
+ L ++ + ++S + S + G K E+ + +S
Sbjct: 786 DAELQALRESVEEATKNVEV----LASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEEL 841
Query: 252 EDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYG 311
E VA+ +E + D KA T + Y E + A+ +E +E+ +
Sbjct: 842 ERRVAQLQRQIEDLKG---DEAKAKETLKKYEGEIRQLEEALVHAR--KEEKEAVSARRA 896
Query: 312 NSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRAKFLRP 371
+ A + ++ + +K + ++ + E RR N +N+ + G K +
Sbjct: 897 LENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKE 956
Query: 372 SDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNS-------EERLTSWSRSDG 424
D S +S L Q L K + +E+ +S
Sbjct: 957 MAD-----------IVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRL 1005
Query: 425 RGDKKHSNQKPSETSTDEHQHVPEDPREKSQ--DEVLRD---DPPKKEHLRDTKSTFAGS 479
K + E ++Q ++ K Q ++ L+D + K HL+D +S
Sbjct: 1006 TAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQ 1065
Query: 480 PERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVE 539
E + + E+ + + ++ + + E EQL+ +L + ++ + +
Sbjct: 1066 MEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQ 1125
Query: 540 NEDQQEVIL-----VRTDQSGRVWPVNTP----GKSLESQGGRRKRQMVSTHEERERVRY 590
N+D + I+ R+ + G V + LES+ R +S +V+
Sbjct: 1126 NKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKE 1185
Query: 591 F---HDDDNLSLND 601
DD++LSL D
Sbjct: 1186 LVMQVDDEHLSLTD 1199
Score = 35.0 bits (79), Expect = 0.31
Identities = 70/383 (18%), Positives = 143/383 (37%), Gaps = 40/383 (10%)
Query: 5 MAAASGRFESAKSIEER-KEQTRNARAEV--LRQAKANFEKEERRKELKRLRGEDTWMLP 61
+A + E K E + KE + E+ L +A + KEE+ R E+ L
Sbjct: 845 VAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENE--LE 902
Query: 62 DVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVE 121
+ Q +QE +K K++ +K + + K + + ++ + + VE
Sbjct: 903 AAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVE 962
Query: 122 AVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIE 181
A + T + + EK+ ++ ++ ++ + +L+AEK + ++
Sbjct: 963 ASRTSTLELQNQLDEYKEKNRRELAEMQRQ-------------LKEKTLEAEKSRLTAMK 1009
Query: 182 QEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMK 241
+ ++ +LME EL Y + L ++ + E S L+ R+
Sbjct: 1010 MQ-----DEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLE-YELEAKSHLKDDRSRLV 1063
Query: 242 EQAEKQSRNFEDIVAERYGSMEIFQSKL-EDAEKAASTKEDYRRERWRKPTYSDKAQNCQ 300
+Q E + E + E + ++ ++ E+ + + +ER A+
Sbjct: 1064 KQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQER--------AARQDL 1115
Query: 301 ESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFS 360
E + L + + R + + S+ E + + + R LE R ES R
Sbjct: 1116 ECDKISLERQNKDLKSRIIHLEGSYRSSKEGLV-VQMEARIAELED-RLESEERDRANLQ 1173
Query: 361 FGNLR-----AKFLRPSDDEELS 378
N R + + DDE LS
Sbjct: 1174 LSNRRLERKVKELVMQVDDEHLS 1196
Score = 30.4 bits (67), Expect = 7.7
Identities = 39/196 (19%), Positives = 76/196 (38%), Gaps = 26/196 (13%)
Query: 20 ERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGED-TWMLPDVNERIEQFSQEHSVKK 78
E K ++ R+ +++Q + + E E +R + + + E++EQ E ++
Sbjct: 1050 EAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQER 1109
Query: 79 KKKKDKHSKKAKKEKKKKSKKQK-------YEKNNES---------SDSSSSSEDEWVEA 122
++D K E++ K K + Y + E ++ E E +
Sbjct: 1110 AARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDR 1169
Query: 123 VPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQ 182
Q ++ KVK+ DD + D+ K S LKA K + + E+
Sbjct: 1170 ANLQLSNRRLERKVKELVMQVDDEHLSLTDQ---------KDQLSLRLKAMKRQVEEAEE 1220
Query: 183 EKNQALEQSKLMEREL 198
E ++ K ++REL
Sbjct: 1221 EIDRLESSKKKLQREL 1236
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 54.7 bits (130), Expect = 4e-07
Identities = 50/279 (17%), Positives = 120/279 (43%), Gaps = 18/279 (6%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
E + E++ Q R +V Q E+E + E + GE + + E++++ +
Sbjct: 161 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEE 220
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPD--K 130
+ ++++ + + + ++E++ + ++++ +K E E E + Q K
Sbjct: 221 QMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280
Query: 131 EKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQ----EKNQ 186
+K ++E++G+ + Q+ +++E M ++ ++E MR+ E+ ++ Q
Sbjct: 281 QKEQTEQEEQTGEQEEQMREQEEQM--------REQEEQMREQEEQMREQEEQMGKQEEQ 332
Query: 187 ALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEK 246
EQ + M + WK E+ +V E+ +RK +M++Q E+
Sbjct: 333 MWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE----QMRKQEEQMRKQEEQ 388
Query: 247 QSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRE 285
+ E + ++ E + E E+ KE R++
Sbjct: 389 MRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQ 427
Score = 52.8 bits (125), Expect = 1e-06
Identities = 34/183 (18%), Positives = 88/183 (48%), Gaps = 13/183 (7%)
Query: 16 KSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHS 75
+ + E++EQ R ++L+Q + ++E+ ++ +++R ++ M + EQ Q
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Query: 76 VKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWK 135
+++ K + +KE+ + K+Q +++ + + ++E ++ Q +E+ +
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE-----QEEQMQKQEEQVRKQEEQMR 376
Query: 136 VKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLME 195
++E+ K + Q+ K++E M + +KE MR+ E++ + EQ + E
Sbjct: 377 KQEEQMRKQEEQMRKQEEQM--------GEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
Query: 196 REL 198
+
Sbjct: 429 EHM 431
Score = 40.0 bits (92), Expect = 0.010
Identities = 26/143 (18%), Positives = 71/143 (49%), Gaps = 11/143 (7%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
E + + E++EQ R ++ Q + ++EE+ E K E W ++ + + Q
Sbjct: 300 EQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQK----EQMW-----EQKEQMWKQ 350
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEK 132
E + +++++ K+ ++ +K++ + +K E+ + ++E + Q ++++
Sbjct: 351 EEQM--GEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKE 408
Query: 133 AWKVKDEKSGKDDTQIIKRDEWM 155
+ ++E+ G+ Q+ K++E M
Sbjct: 409 QMREQEEQMGEQKEQMRKQEEHM 431
Score = 38.5 bits (88), Expect = 0.028
Identities = 23/131 (17%), Positives = 63/131 (48%), Gaps = 4/131 (3%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
E + + E++EQ R ++ +Q + +E++E+ E K E W + E+ Q
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQK----EQMWKQEEQMGEQEEQMQ 362
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEK 132
+ + +K++++ K+ ++ +K++ + +K E+ + E + Q ++++
Sbjct: 363 KQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKE 422
Query: 133 AWKVKDEKSGK 143
+ ++E G+
Sbjct: 423 QMRKQEEHMGE 433
Score = 32.7 bits (73), Expect = 1.5
Identities = 65/447 (14%), Positives = 165/447 (36%), Gaps = 29/447 (6%)
Query: 19 EERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKK 78
EE KE+ + E+ E + KELKR D LP + EQ Q +
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 79 KKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKD 138
+ ++ + + ++ + ++ + Q E+ + + ++ + + +E+ +V++
Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
Query: 139 EKS--GKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAE---KETMRKIEQEKNQALEQ-SK 192
++ + + Q+ +++ + V+ + E +E ++ +++ Q EQ +
Sbjct: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
Query: 193 LMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFE 252
+ E+E ++G G E ++K +M EQ E+Q R E
Sbjct: 187 VREQEGQMGEQEGQMGEQEEQMGEQE------------EQMQKQEEQMGEQ-EEQMRKQE 233
Query: 253 DIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGN 312
+ + E+ ++ + +++ E+ +E+ RE + + +E E L +
Sbjct: 234 EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE---------QEEQMREQEEQMLKQKEQ 284
Query: 313 SSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRAKFLRPS 372
+ ++ + E+ + +++++ E R + QE + +
Sbjct: 285 TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQK 344
Query: 373 DDEELSFHSKGRKFEPLSSSSALV-AQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHS 431
+ G + E + V Q + + EE++ G ++
Sbjct: 345 EQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMG 404
Query: 432 NQKPSETSTDEHQHVPEDPREKSQDEV 458
QK +E ++ K ++ +
Sbjct: 405 EQKEQMREQEEQMGEQKEQMRKQEEHM 431
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 54.7 bits (130), Expect = 4e-07
Identities = 44/188 (23%), Positives = 87/188 (46%), Gaps = 17/188 (9%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNE--RIEQF 70
ES + E R+ + R E ++ K K+E++K KR RG++ E R E+
Sbjct: 33 ESERKKERREREKRKRERE--KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 71 SQEHSVKKKKKKDKHSK-KAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPD 129
+E +KK+KK + K + ++E+KKK ++++ E+ N+ + + + +
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Query: 130 KEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALE 189
KE+ + + K K + + KR+ + K E+E + E++K + E
Sbjct: 151 KERGKRERKRKKRKKEEREKKRER------------NRKERKKERERKERRERKKERKKE 198
Query: 190 QSKLMERE 197
+ K ER+
Sbjct: 199 RRKKKERK 206
Score = 50.1 bits (118), Expect = 9e-06
Identities = 28/106 (26%), Positives = 57/106 (53%), Gaps = 7/106 (6%)
Query: 11 RFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQF 70
R E + ++R+E+ R R + R+ + EKE ++E KR + + ER ++
Sbjct: 120 RKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKK-------EEREKKR 172
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSE 116
+ +KK+++ K ++ KKE+KK+ +K+K K + +D + S+
Sbjct: 173 ERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 48.1 bits (113), Expect = 4e-05
Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 9/140 (6%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
E K E ++++ R E + + +KE++++E K+ + + ER + Q
Sbjct: 70 ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129
Query: 73 EHSVKKKKKKDKHSKKAKK---------EKKKKSKKQKYEKNNESSDSSSSSEDEWVEAV 123
K+KK++ K +K +K K+KK KK++ EK E + E E E
Sbjct: 130 RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189
Query: 124 PSQTPDKEKAWKVKDEKSGK 143
+ K++ K K+ K +
Sbjct: 190 ERKKERKKERRKKKERKKDR 209
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/148 (20%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
E + +ER++Q + R + R+ K +K ER++ +R R + E ++ +
Sbjct: 74 ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRER 133
Query: 73 EHSVKKKKKKDKHSKKAK---------KEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAV 123
+ ++KKK+ K K+ K K++KK+ +++K E+N + ++
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193
Query: 124 PSQTPDKEKAWKVKDEKSGKD-DTQIIK 150
+ ++K + KD K+ + D+Q+ +
Sbjct: 194 ERKKERRKKKERKKDRKTDRQTDSQVFR 221
Score = 36.6 bits (83), Expect = 0.11
Identities = 38/183 (20%), Positives = 76/183 (41%), Gaps = 35/183 (19%)
Query: 15 AKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEH 74
+K +R+ + + R E ++ K ER KE KR RG+ +E
Sbjct: 26 SKPCTQRESERKKERREREKR------KREREKERKRERGK----------------KEK 63
Query: 75 SVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAW 134
+KK+++ K ++ +KE++K+ +K++ EK + + KE+
Sbjct: 64 KKRKKRERGKERERKRKEREKQ-RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122
Query: 135 KVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKET-MRKIEQEKNQALEQSKL 193
+ ++ K ++ + +R K K EKE R+ +++K + E+ K
Sbjct: 123 RERENKQRRERKRKKRR-----------KKKRRKERKREKERGKRERKRKKRKKEEREKK 171
Query: 194 MER 196
ER
Sbjct: 172 RER 174
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 54.3 bits (129), Expect = 5e-07
Identities = 35/152 (23%), Positives = 75/152 (49%), Gaps = 10/152 (6%)
Query: 11 RFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQF 70
R + K E +KE+ + ++ K EKE+R+K+ K+ RG + + + E+
Sbjct: 81 RGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK 140
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDS--------SSSSEDEWVEA 122
+E +++KK+++ ++ +KE+KK+ +KQ EK E + + ++ E
Sbjct: 141 REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
Query: 123 VPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEW 154
+ +++K K K+E+ K + Q ++ W
Sbjct: 201 ERKERRERKKERKKKEER--KKERQKDRQTNW 230
Score = 53.9 bits (128), Expect = 6e-07
Identities = 44/206 (21%), Positives = 97/206 (47%), Gaps = 19/206 (9%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFE-KEERRKELKRLRGEDTWMLPDVNERIEQFS 71
E + IE RKE + +E ++ + + K ER KE KR RG+ E+ +
Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK--------KEKKGERK 91
Query: 72 QEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKE 131
+E +KK++++K +K+ +EK+K+ KK+K E+ S + E + + +++
Sbjct: 92 KEERERKKRRREKENKEG-EEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
Query: 132 KAWKVKD----EKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLK-----AEKETMRKIEQ 182
K + K+ E+ ++ Q+ +++E + + K E++ R+ ++
Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
Query: 183 EKNQALEQSKLMERELNPYWKDGGTG 208
E+ + E+ K +++ W++ G
Sbjct: 211 ERKKKEERKKERQKDRQTNWREKERG 236
Score = 49.3 bits (116), Expect = 2e-05
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 11/127 (8%)
Query: 10 GRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQ 69
GR ERKE+ + + + K EKE RKE K+ + V E+ E+
Sbjct: 124 GRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERK------QVGEK-EE 176
Query: 70 FSQEHSVKKKKKKDKHSKKAKKEKKKKS----KKQKYEKNNESSDSSSSSEDEWVEAVPS 125
+E K++KK++++ K+ KKE+++K KK++ +K + + W E
Sbjct: 177 ERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERG 236
Query: 126 QTPDKEK 132
+ KE+
Sbjct: 237 KRERKER 243
Score = 35.8 bits (81), Expect = 0.18
Identities = 47/248 (18%), Positives = 105/248 (42%), Gaps = 47/248 (18%)
Query: 62 DVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKK--KSKKQKYEKNNESSDSSSSSEDEW 119
++ ER + KK+++ ++ ++ ++EK+K + K++K E+ + E+
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER- 95
Query: 120 VEAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRK 179
+++K + K+ K G++ + K++ K + K KE RK
Sbjct: 96 ---------ERKKRRREKENKEGEEKEKRKKKE----------KKERGRTSKEGKERERK 136
Query: 180 IEQEKNQALE-QSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYL 238
E+++ + E + K ERE K+ K + G RK
Sbjct: 137 EERKREERKERERKKEEREKERERKER--------------KKRERKQVGEKEEERKE-- 180
Query: 239 RMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERW--RKPTYSDKA 296
+ +++ +K+ RN ++ ER + + + +K KE+ ++ER R+ + +K
Sbjct: 181 KERKERKKRERNRKERKKERE------RKERRERKKERKKKEERKKERQKDRQTNWREKE 234
Query: 297 QNCQESRE 304
+ +E +E
Sbjct: 235 RGKRERKE 242
Score = 31.6 bits (70), Expect = 3.4
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 15/197 (7%)
Query: 171 KAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGL 230
K E+E+ RK E+ + + ++ + ER+ K+ E+ + ++G
Sbjct: 52 KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111
Query: 231 SWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKP 290
RK KE+ E+ + E ER + K E+ ++ KE+ +ER RK
Sbjct: 112 KEKRKK----KEKKERGRTSKEGKERERKE-----ERKREERKERERKKEEREKERERKE 162
Query: 291 TYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRE 350
+ + E E ++R +N K + K++R E ++E
Sbjct: 163 RKKRERKQVGEKEEE------RKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216
Query: 351 SNPRQNQEFSFGNLRAK 367
++ Q+ N R K
Sbjct: 217 ERKKERQKDRQTNWREK 233
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 53.9 bits (128), Expect = 6e-07
Identities = 61/271 (22%), Positives = 107/271 (39%), Gaps = 13/271 (4%)
Query: 221 KVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVA-ERYGSMEIFQSKLEDAEKAASTK 279
K+ +VED S R+SY R + + +SR+ + R GS + SK ++ S
Sbjct: 169 KIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRS 228
Query: 280 EDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNS-NNEKFIGDEKD 338
R R + + S K ++ S+E + ++ + R + D A+ N +G K
Sbjct: 229 RSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKS 288
Query: 339 KRPG---SLETCRRESNPRQNQEFSFGNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSAL 395
+ P S R S R+ +E G++ +E S + S +
Sbjct: 289 RSPSRHKSKSKSRSRSQERRVEEEKRGSVSR-----GRSQEKSLRQSRSRSRSKGGSRSR 343
Query: 396 VAQGSLCSGFRKPTKNS--EERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHVPEDPREK 453
S RK K S E R S SRS +K +++ S+ + + + + R +
Sbjct: 344 SRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQ 403
Query: 454 SQDEVLRDDPPKKEHLRDTKSTFAGSPERES 484
S+ R ++EH + S G E E+
Sbjct: 404 SRSP-SRSVSKEREHAKSESSQREGRGESEN 433
Score = 45.8 bits (107), Expect = 2e-04
Identities = 67/335 (20%), Positives = 126/335 (37%), Gaps = 71/335 (21%)
Query: 64 NERIEQFSQEHSVKKKKKKDKHSKKAKKE----KKKKSKKQKYEKNNESSDSSSSSEDEW 119
+ R +S+ S + + + +HS+K++ K SK + ++ S S S S +
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 120 ---VEAVPSQTPDKEK-------AWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSS 169
+ S++P KEK A K + + + + +I D S S S
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298
Query: 170 LKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGG 229
+ R++E+EK ++ + + E+
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKS-------------------------------- 326
Query: 230 LSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRK 289
LR+S R + + +SR+ +SK +D K + R R R
Sbjct: 327 ---LRQSRSRSRSKGGSRSRSRS-------------RSKSKDKRKGRKRSREESRSRSRS 370
Query: 290 PTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKD--KRPGSLETC 347
+ S++++ R+S K G+S + + TD +++ + + + E++ K S
Sbjct: 371 RSKSERSRKRGSKRDS---KAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREG 427
Query: 348 RRES-NPRQNQEF---SFGNLRAKFLRPSDDEELS 378
R ES N NQE S N ++K PS+ S
Sbjct: 428 RGESENAGTNQETRSRSRSNSKSKPNLPSESRSRS 462
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 53.9 bits (128), Expect = 6e-07
Identities = 62/334 (18%), Positives = 140/334 (41%), Gaps = 44/334 (13%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
E + +E+K+ A + +++A A ++EE R++ + ERI++ +
Sbjct: 324 EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREE------------EERIKRLEE 371
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEA---------- 122
+ +K++++ + K+ +K++K+K +K++ +K + S EA
Sbjct: 372 LEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGV 431
Query: 123 -VPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIE 181
VPS+ +K +D+K K Q+ ++ +++ + V + ++ET +E
Sbjct: 432 EVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVE 491
Query: 182 QEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMK 241
E+ + E + L + E +++S + VE + K +
Sbjct: 492 PEEEEDTEDAGLDDWE-----------------AMASDEETEKVEGNKVHIEVKENPEEE 534
Query: 242 EQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPT---YSDKAQN 298
E+ E++ E+ E E S+ ++ ++ S ++D + +KP+ SD +
Sbjct: 535 EEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYD 594
Query: 299 CQESRESDLVKYGNSSRD-RYATTDTAKNSNNEK 331
+ R + Y + R + +KN N EK
Sbjct: 595 SDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEK 628
Score = 50.8 bits (120), Expect = 5e-06
Identities = 78/385 (20%), Positives = 152/385 (39%), Gaps = 64/385 (16%)
Query: 15 AKSIEERKEQTRNARAEVLRQAKANFEKEE---------RRKELKRLRGE---------D 56
A+ E+KE+ R R E + + EKEE ++KE +R E D
Sbjct: 229 AQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVD 288
Query: 57 TWMLPDVNERIEQ--FSQEHSVKKKKKKDKHSKKAKKEKKKKSKK------------QKY 102
T ++P E+ E +++ + KKKKDK KK +KE+K+K KK +
Sbjct: 289 TGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEAL 348
Query: 103 EKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSV 162
K E + E+E ++ + +++ +++ EK + + +R E + + +
Sbjct: 349 AKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKE-GKL 407
Query: 163 KTVSSSSLKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITK- 221
T S +A E K+ Q + + + ++ P ++D P+ +++
Sbjct: 408 LTKSQREARARAEATLKLLQAQGVEVPSKDSLPKK-RPIYEDKKRKKIPQQLESKEVSES 466
Query: 222 ------VSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKA 275
V V+E G + KE+ E+ E G L+D E
Sbjct: 467 MELCAAVEVMEQG---------VPEKEETPPPVEPEEEEDTEDAG--------LDDWEAM 509
Query: 276 ASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGD 335
AS +E + E + + +N +E E + D + + + +E GD
Sbjct: 510 ASDEETEKVE--GNKVHIEVKENPEEEEEEE----EEEEEDEESEEEEEEEGESEGSEGD 563
Query: 336 EKDKRPGSLETCRRESNPRQNQEFS 360
E+D++ + + + + ++E S
Sbjct: 564 EEDEKVSDEKDSGKTLDKKPSKEMS 588
Score = 47.8 bits (112), Expect = 5e-05
Identities = 120/639 (18%), Positives = 243/639 (38%), Gaps = 106/639 (16%)
Query: 82 KDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSS--------EDEWVEAVPSQTPDKEKA 133
K++ +K+K +KKK+ KKQ +++++ + S + E V P++ ++E
Sbjct: 33 KEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFT 92
Query: 134 WKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKL 193
K K +K K Q ++ ++ K+ ++ K E + + + N+ +++K
Sbjct: 93 SKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKG 152
Query: 194 MERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLS------WLRKSYLRMKEQAEKQ 247
++ N W G ++ + I + S + G S +L+ + K Q K
Sbjct: 153 KAQKSNKKW----DGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKP 208
Query: 248 SRNFED------------IVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDK 295
N E VA++ + + K D EKA K + E K
Sbjct: 209 GPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSK 268
Query: 296 AQNCQESRESDLVKYGNS-------SRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCR 348
+ Q E + VK + + + A T TA +NE GD+K K + +
Sbjct: 269 QKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNE---GDKKKKDKKKKKGEK 325
Query: 349 RESNPRQNQEFSFGNLRA---KFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGF 405
E + + S ++A + ++EE + + + L A
Sbjct: 326 EEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEA----------- 374
Query: 406 RKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHVPEDPRE-KSQDEVLRDDPP 464
+ EERL + R KK ++ E E + + + RE +++ E
Sbjct: 375 ---KRKEEERL----EQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEAT----- 422
Query: 465 KKEHLRDTKSTFAGSPERESI----HILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLE 520
L+ ++ P ++S+ I ++ K+ ++ E+ +MEL ++V +
Sbjct: 423 ----LKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQ 478
Query: 521 KANKFKETITQIPKKSGVENEDQQEVILVRTDQSG-RVWPVNTPGKSLES-QGGRRKRQM 578
+ +ET VE E++++ T+ +G W + E +G + ++
Sbjct: 479 GVPEKEET------PPPVEPEEEED-----TEDAGLDDWEAMASDEETEKVEGNKVHIEV 527
Query: 579 VSTHEERERVRYFHDDDNLSLNDL------------VKNEKMGTAENQNKLFMRMASKFM 626
EE E ++D S + ++EK+ ++ K + SK M
Sbjct: 528 KENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEM 587
Query: 627 GKTDGDYYTLDDMFVSKAAERERLGEEEENQRKKAIAEH 665
+D +Y + DD + ER ++ + + +K EH
Sbjct: 588 -SSDSEYDSDDD-----RTKEERAYDKAKRRIEKRRLEH 620
Score = 45.8 bits (107), Expect = 2e-04
Identities = 102/529 (19%), Positives = 194/529 (36%), Gaps = 82/529 (15%)
Query: 14 SAKSIEERKEQ--TRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFS 71
+ K E +E+ +++ + + + K +F+ + + L +D+ ++E +S
Sbjct: 80 AVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEE----LEDKDSKSKKTAKPKVEMYS 135
Query: 72 -----QEHSVKKKKKKDKHSKKAKK-----EKKKKSKKQKYEKNNESSDSSSSSEDEWVE 121
+ + KK K K K KK E + SKK K SS S DE+++
Sbjct: 136 GSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQ 195
Query: 122 AVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIE 181
+ Q +++ E +DD K +KTV+ KAEK+ + +
Sbjct: 196 SRKGQKKNQKNKPGPNIESGNEDDDASFK-----------IKTVAQK--KAEKKERERKK 242
Query: 182 QEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMK 241
+++ +A + + EL KD + K V D G+ +
Sbjct: 243 RDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGV------IPASE 296
Query: 242 EQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYS-------- 293
E+AE + +D ++ K +D +K KE+ +E+ + P+ +
Sbjct: 297 EKAETPTAAEDDNEGDK---------KKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA 347
Query: 294 ----DKAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKD-----KRPGSL 344
+ + Q+ E + +K + + + E+ EK+ K+ G L
Sbjct: 348 LAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKL 407
Query: 345 ETCRRESNPRQNQEFSFGNLRAKFLR-PSDD----EELSFHSKGRKFEPLSSSSALVAQG 399
T + + R E + L+A+ + PS D + + K RK P S V++
Sbjct: 408 LT-KSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSES 466
Query: 400 -SLCSGFR-------------KPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQH 445
LC+ P + EE T + D + H
Sbjct: 467 MELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIE 526
Query: 446 VPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVDEKN 494
V E+P E+ ++E ++ + E + + GS E +S DEK+
Sbjct: 527 VKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVS-DEKD 574
Score = 45.4 bits (106), Expect = 2e-04
Identities = 93/510 (18%), Positives = 195/510 (38%), Gaps = 72/510 (14%)
Query: 93 KKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGK-DDTQIIKR 151
KK+K+K + K++ D+ ++ E E A Q P K K K K++K D+ I+K
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAA-EIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKE 61
Query: 152 DEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQ----ALEQSKLMERELNPYWKDGGT 207
E ++++ + +KA++ET+ E N+ + ++ K ++ + D +
Sbjct: 62 LEELSLE--------AQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDS 113
Query: 208 GLPPEDCSVSSITKVSVVE-------DGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYG 260
+ S S T VE D + L K + K +A+K ++ ++ +
Sbjct: 114 EELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPK---KAKGKAQKSNKKWDGSEEDEDN 170
Query: 261 SMEIFQ-SKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYA 319
S +I + S++ + ++ +++ + R + +N Q+++ ++ GN D
Sbjct: 171 SKKIKERSRINSSGESGDESDEFLQSR------KGQKKN-QKNKPGPNIESGNEDDDASF 223
Query: 320 TTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRAK-FLRPSDDEELS 378
T EK RE R ++ L+ K L ++
Sbjct: 224 KIKTVAQKKAEK---------------KERERKKRDEEKAKLRKLKEKEELETGKKDQSK 268
Query: 379 FHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSET 438
RKFE + S + + P + + + D GDKK ++K +
Sbjct: 269 QKESQRKFEEETVKSKVTVDTGVI-----PASEEKAETPTAAEDDNEGDKKKKDKKKKK- 322
Query: 439 STDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVDEKNKLGA 498
EK + E + P K ++ + A E E +E+ K
Sbjct: 323 ------------GEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIK--- 367
Query: 499 KIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENEDQQEVILVRTDQSGRVW 558
++ + E E + + + K K KE ++ K+ + + Q+E R +
Sbjct: 368 RLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQRE---ARARAEATLK 424
Query: 559 PVNTPGKSLESQGGRRKRQMVSTHEERERV 588
+ G + S+ K++ + ++R+++
Sbjct: 425 LLQAQGVEVPSKDSLPKKRPIYEDKKRKKI 454
Score = 43.9 bits (102), Expect = 7e-04
Identities = 42/205 (20%), Positives = 93/205 (45%), Gaps = 35/205 (17%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
ES + ++ RK Q +N + + ++ E ++ ++K + Q
Sbjct: 189 ESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKT---------------VAQKKA 233
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEA--------VP 124
E +++KK+D+ K +K K+K+ + + ++ +S E+E V++ +P
Sbjct: 234 EKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIP 293
Query: 125 -----SQTP-----DKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSS--SSLKA 172
++TP D E K KD+K K + + ++++ +VK + + LK
Sbjct: 294 ASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKE 353
Query: 173 EKETMRKIEQEKNQALEQSKLMERE 197
E+E ++ E+E+ + LE+ + +E
Sbjct: 354 EEERQKREEEERIKRLEELEAKRKE 378
Score = 32.0 bits (71), Expect = 2.6
Identities = 28/136 (20%), Positives = 55/136 (40%), Gaps = 13/136 (9%)
Query: 15 AKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEH 74
A + +E E+ + + + K N E+EE +E + + +E E+ +E
Sbjct: 508 AMASDEETEKVEGNKVHI--EVKENPEEEEEEEEEE-----------EEDEESEEEEEEE 554
Query: 75 SVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAW 134
+ + D+ +K EK K SSDS S+D+ + + K +
Sbjct: 555 GESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIE 614
Query: 135 KVKDEKSGKDDTQIIK 150
K + E S +T+ ++
Sbjct: 615 KRRLEHSKNVNTEKLR 630
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 53.5 bits (127), Expect = 8e-07
Identities = 50/187 (26%), Positives = 85/187 (45%), Gaps = 32/187 (17%)
Query: 29 RAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSV------------ 76
R E LRQ + + R+ + L + W L N E S EH+
Sbjct: 122 REESLRQKRLS-----ERERIGELGAPEVWGLSPKNP--EPDSDEHTPVEDEEPKKSTTS 174
Query: 77 ------KKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDK 130
+KKKK + +++KK +KKKS K+K++K +E SDS S SE + S +K
Sbjct: 175 ASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETD-----SSDEDNK 229
Query: 131 EKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQ 190
+A K K ++ K K+ + ++ SSS ++++E + +++ +A E
Sbjct: 230 RRAKKAKKKEKKKKHRS--KKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEP 287
Query: 191 SKLMERE 197
S L+ E
Sbjct: 288 SDLIGPE 294
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Query: 14 SAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQE 73
SA + EE K++ + E R K +K +RK K D+ + + E ++
Sbjct: 174 SASTSEEEKKKKSSRSKE--RSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDED-NKR 230
Query: 74 HSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSS--EDEWVEAVPSQTP 128
+ K KKK+ K ++KK KKK+SKK + E ++ SS S E+ W + ++ P
Sbjct: 231 RAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEP 287
Score = 44.3 bits (103), Expect = 5e-04
Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 10/127 (7%)
Query: 19 EERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKK 78
EE K+ T +A + K + +ER K+ +R + +E + S +
Sbjct: 166 EEPKKSTTSASTSEEEKKKKSSRSKERSKK-RRKKKSSKRKHKKYSEDSDSDSDSETDSS 224
Query: 79 KKKKDKHSKKAKK-EKKKKSKKQKYEK------NNESSDSSSSSEDEWVEAVPSQTPDKE 131
+ + +KKAKK EKKKK + +KY+K ESSDSSS E E + + D+
Sbjct: 225 DEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQE--EFLENPWKDRT 282
Query: 132 KAWKVKD 138
KA + D
Sbjct: 283 KAEEPSD 289
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 53.5 bits (127), Expect = 8e-07
Identities = 141/722 (19%), Positives = 283/722 (39%), Gaps = 99/722 (13%)
Query: 16 KSIEERKEQTR--NARAEVLRQAKANFEKEERRKELKRLR----GEDTWM---LPDVNER 66
++I+ KEQ + E L++ + +ER +EL++++ E T + L D
Sbjct: 300 ETIQSHKEQCTLLTSEKEALQE-----QLDERLQELEKIKDLHMAEKTKLITQLRDAKNL 354
Query: 67 IEQFSQEHS-VKKKKKKDKHSKKAKKEKK----KKSKKQKYEKNNESSDSSSSSEDEWVE 121
IEQ Q+ V + K+ H KE++ + KQ + E + SE E
Sbjct: 355 IEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFE 414
Query: 122 AVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIE 181
+ +K + + + + D QI ++ + +S++ S + + M+K
Sbjct: 415 ELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 474
Query: 182 QEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMK 241
+E+ L+ KL E+EL ++ L + KV++ + + YL++
Sbjct: 475 EEQIAKLQ--KLHEKELARKEQELTKKLQTREREFQEQMKVALEKS------QSEYLKIS 526
Query: 242 EQAEKQ-SRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQ 300
++ E+Q S E++ ++ + ++KL D ++ A T Y + +
Sbjct: 527 QEKEQQESLALEELELQKKAILTESENKLRDLQQEAET-------------YRTRILELE 573
Query: 301 ESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNP------- 353
S E L + N S+D + KN +N K I +K LE+ + + +
Sbjct: 574 SSLEKSLQENKNQSKDLAVHLEAEKNKHN-KEITVMVEKHKTELESLKHQQDALWTEKLQ 632
Query: 354 --RQNQEFSFGNLRAKFLRPSD----DEELSFHS---------------KGRKFEPLSS- 391
+Q + LR K + + D+E+ F + K + E LSS
Sbjct: 633 VLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSE 692
Query: 392 -SSALVAQGSL---CSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHVP 447
S L A+ L S + T ++ L + ++K+ +Q+ ++ EH+
Sbjct: 693 LSEVLKARHKLEEELSVLKDQTDKMKQELEA-----KMDEQKNHHQQQVDSIIKEHEVSI 747
Query: 448 EDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVDEKNKLGAKI-----IK 502
+ + +D++ + + KE + K A E+ S E + AK+ +
Sbjct: 748 QRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQ 807
Query: 503 AEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVENEDQQEVILVRTDQSGRVWPVNT 562
+ + E+ QL++ ET + K E E Q++ + T+ V
Sbjct: 808 SATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVC--TELDAHKIQVQD 865
Query: 563 PGKSLESQGGRRKRQMVS-THEERERVRYFHDDDNLSLNDLVKNEKM--GTAENQNKLFM 619
+ LE Q ++++ S T ++ + + + LV+ E M E Q K
Sbjct: 866 LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIE 925
Query: 620 RMASKFMGKTDGDYYTLDDMFVSKAAERERLGEE--------EENQRKKAIAEHRSLAAQ 671
+ K K D + L++ + +K +E+ E+ +E +KK + + L +
Sbjct: 926 ILTQKLSAKED-SIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKE 984
Query: 672 ME 673
+E
Sbjct: 985 LE 986
Score = 47.0 bits (110), Expect = 8e-05
Identities = 128/671 (19%), Positives = 247/671 (36%), Gaps = 67/671 (9%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANF--EKEERRKELKRLRGEDTWMLPDVNERIEQF 70
E + I E + Q + L+Q F EKEE KE+ L+ E +NE EQ
Sbjct: 1056 EELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQL 1115
Query: 71 SQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKN-NESSDSSSSSEDEWVEAVPSQTPD 129
K+K + A+ E K K+ +K E + N+S ++ +++ VE D
Sbjct: 1116 --------KQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEED 1167
Query: 130 KEKAWKVKDE-KSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQAL 188
K K ++ + K+ ++ Q +K + + K++ L E I +K +AL
Sbjct: 1168 KRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEAL 1227
Query: 189 EQSKLMERELNPYWKDGGTGLPPEDCS--VSSITKVSVVEDGGLSWLRKSYLRMKEQAEK 246
++K E K C + + + +++ +S L ++ E+
Sbjct: 1228 LEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNT 1287
Query: 247 QSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESD 306
+ +F+ + +S D E + KE ++E + + + ++C + +
Sbjct: 1288 LNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE 1347
Query: 307 LVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEFSFGNLRA 366
L S + A T + +K K+ L + S +E + +LR
Sbjct: 1348 L------SENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRK 1401
Query: 367 KFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRG 426
++ DEE K E L L + S K ++ E++ WS
Sbjct: 1402 QY-----DEE--------KCELLDQVQDLSFKVDTLS---KEKISALEQVDDWSNKFSEW 1445
Query: 427 DKKHSNQKPSETSTDEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIH 486
KK ++ +T + + + + K E KE L F + +
Sbjct: 1446 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRF------DCLK 1499
Query: 487 ILSVDEKNKLGAK------IIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKSGVEN 540
D+K+K+ K +K++ MEL + + + + E + ++ +E+
Sbjct: 1500 GEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEH 1559
Query: 541 ED----QQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDN 596
++ Q + ++ RV +LE+Q K ++ + +E E V N
Sbjct: 1560 KELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHV-------N 1612
Query: 597 LSLNDLVKNEKMGTAENQNKLFMRMASKFMGKTDGDYYTLDDMFVSKAAERERLGEEEEN 656
LS+ K E++ E+ R+ S+ K + + + EE+E
Sbjct: 1613 LSVKS--KEEELKALED------RLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEE 1664
Query: 657 QRKKAIAEHRS 667
Q KK H S
Sbjct: 1665 QYKKGTESHLS 1675
Score = 38.5 bits (88), Expect = 0.028
Identities = 42/178 (23%), Positives = 86/178 (48%), Gaps = 21/178 (11%)
Query: 36 AKANFEKEERRKELKRLRGEDTWMLPDVNERIE----QFSQEHSVKKKKKKD----KHSK 87
A A EK++ KE+ RL+ + + + + +E ++ QE K K++++ KH+
Sbjct: 1933 AGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNS 1992
Query: 88 KAKKEKKK-----KSKKQKYEKN-NESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDE-- 139
K+ ++ K+Q+ E E+ + + E E +E+ +T K KD+
Sbjct: 1993 TLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDL 2052
Query: 140 -KSGKDDTQII-KRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLME 195
++ K +I+ R+E MT V+ + + + +K+ +K+EQE+N + +ME
Sbjct: 2053 KRTAKRYEEILDAREEEMTA---KVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIME 2107
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 53.1 bits (126), Expect = 1e-06
Identities = 133/729 (18%), Positives = 289/729 (39%), Gaps = 124/729 (17%)
Query: 1 MATSMAAASGRFESAKS-IEERKEQTRNARAEVLRQAKANFEKEERRK-----ELKRLRG 54
+A A+ E K +E+ Q R E+L KA+FEK K EL R+R
Sbjct: 1895 LAQLRKASDSELERQKGLVEDTLRQRRQVEEEILA-LKASFEKAAAGKAELELELGRIRS 1953
Query: 55 EDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKK-----AKKEKKKKSKKQKYEKNNESS 109
+ E +++ K++ + + + A++E++++ +++ +K+ +
Sbjct: 1954 ----------------NAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAE 1997
Query: 110 DSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSS 169
+ ++ +E V E+A ++++ + Q+ E +
Sbjct: 1998 EEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQE-----------AAQKR 2046
Query: 170 LKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGG 229
L+AE++ Q+K Q L+Q+ E+ + + G + +V +
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR-GEAEAARRAAEEAEEARVQAEREAA 2105
Query: 230 LSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRK 289
S R E+AE+ ++ E+ R + + ++AE+ A+ + + R+
Sbjct: 2106 QS------RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQ 2159
Query: 290 PTYSD-KAQNCQESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKR--PGSLET 346
+D + + ++ E L + ++ + ++++K + DE+ +R + E
Sbjct: 2160 KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2219
Query: 347 CRRESNPR--------QNQEFSF------GNLRAKFLRPSDDEELSFHSKGRKFEPLSSS 392
R+ S Q +E S RA LR D+ + + K + ++
Sbjct: 2220 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2279
Query: 393 SALVAQGSLCSGFRKPTKNSEERLTSWSRSDGRGDKKHSNQKPSETSTDEHQHVPEDPRE 452
+A ++ + RL + D + + + E + Q V E R
Sbjct: 2280 AARLSVAA----------QEAARLRQLAEEDLAQQRALAEKMLKE----KMQAVQEATRL 2325
Query: 453 KSQDEVLRDDPPKKEHLRDTKSTFAGSPERESIHILSVDEKNKLGAKIIKAEMMGNMEL- 511
K++ E+L+ +KE ++ E+ + + E+ + + ++AE +E+
Sbjct: 2326 KAEAELLQQ---QKELAQEQARRLQEDKEQMAQQLA---EETQGFQRTLEAERQRQLEMS 2379
Query: 512 --AEQLKVQL-----------EKANKFKETITQIPKK-SGVENEDQQEVILVRTDQSGRV 557
AE+LK+++ E A +F++ +I +K E Q++V LV+T + R
Sbjct: 2380 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQR- 2438
Query: 558 WPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGTAENQNKL 617
R R+ ++ ERE+ + + L L K+E+M T + + L
Sbjct: 2439 --------QQSDHDAERLREAIA-ELEREKEKLQQEAKLLQL----KSEEMQTVQQEQLL 2485
Query: 618 FMRMA--SKFMGKTDG----------DYYTLDDMFVSKAAERERLGEEEENQRKKAIAEH 665
A F+ + D + L+ +F + A+ ++L EE++ Q+++ E
Sbjct: 2486 QETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQER 2545
Query: 666 RSLAAQMEK 674
+ L A ME+
Sbjct: 2546 QRLVASMEE 2554
Score = 33.5 bits (75), Expect = 0.91
Identities = 52/283 (18%), Positives = 112/283 (39%), Gaps = 34/283 (12%)
Query: 13 ESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQ 72
E A+ ++E KEQ AE + + E E +R+ E + R + ++
Sbjct: 2341 EQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAE 2400
Query: 73 EHSVKKKKKKDKHSKKAKKEKKKKSKK----QKYEKNNESSDSSSSSEDEWVEAVPSQTP 128
E + + +K+ ++ +K + + +K Q E + SD + E + + +
Sbjct: 2401 EDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2460
Query: 129 DKEKAWKVKDEKSGKDDT----QIIKRDEWMTVDFMSVKT--------VSSSSLKAEK-- 174
++ K+ KS + T Q+++ + + F+S K + K E+
Sbjct: 2461 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2520
Query: 175 -ETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWL 233
+ + K +Q + + Q + ME+E V+S+ + + +
Sbjct: 2521 QDEVAKAQQLREEQQRQQQQMEQERQRL--------------VASMEEARRRQHEAEEGV 2566
Query: 234 RKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAA 276
R+ + +Q E+Q R E+++AE + LE+ +AA
Sbjct: 2567 RRKQEEL-QQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAA 2608
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,542,934
Number of Sequences: 37866
Number of extensions: 1642101
Number of successful extensions: 19756
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 321
Number of HSP's successfully gapped in prelim test: 765
Number of HSP's that attempted gapping in prelim test: 10021
Number of HSP's gapped (non-prelim): 5266
length of query: 894
length of database: 18,247,518
effective HSP length: 111
effective length of query: 783
effective length of database: 14,044,392
effective search space: 10996758936
effective search space used: 10996758936
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.