Search of human proteins with 169234945

Search of human proteins with 169234945

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169234945 SH2 domain protein 1A isoform 2 [Homo sapiens]
         (125 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169234945 SH2 domain protein 1A isoform 2 [Homo sapiens]           257   2e-69
gi|4506923 SH2 domain protein 1A isoform 1 [Homo sapiens]             251   8e-68
gi|54792745 SH2 domain containing 1B [Homo sapiens]                   108   1e-24
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ...    92   8e-20
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ...    92   8e-20
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap...    86   6e-18
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a...    60   6e-10
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b...    60   6e-10
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]              55   1e-08
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]                55   1e-08
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]              55   1e-08
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]              55   1e-08
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]              55   1e-08
gi|158631203 dual adaptor of phosphotyrosine and 3-phosphoinosit...    50   4e-07
gi|205277435 spleen tyrosine kinase isoform 2 [Homo sapiens]           49   1e-06
gi|21361553 spleen tyrosine kinase isoform 1 [Homo sapiens]            49   1e-06
gi|4503787 fyn-related kinase [Homo sapiens]                           46   8e-06
gi|187475373 c-src tyrosine kinase [Homo sapiens]                      45   2e-05
gi|4758078 c-src tyrosine kinase [Homo sapiens]                        45   2e-05
gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]                 45   2e-05
gi|48762697 growth factor receptor-bound protein 10 isoform c [H...    44   4e-05
gi|48762695 growth factor receptor-bound protein 10 isoform c [H...    44   4e-05
gi|48762693 growth factor receptor-bound protein 10 isoform b [H...    44   4e-05
gi|48762679 growth factor receptor-bound protein 10 isoform a [H...    44   4e-05
gi|5729856 GRB2-related adaptor protein [Homo sapiens]                 43   7e-05
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap...    42   9e-05
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi...    42   9e-05
gi|4757980 beta chimerin isoform 2 [Homo sapiens]                      42   9e-05
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]             42   1e-04
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]           42   1e-04

>gi|169234945 SH2 domain protein 1A isoform 2 [Homo sapiens]
          Length = 125

 Score =  257 bits (656), Expect = 2e-69
 Identities = 125/125 (100%), Positives = 125/125 (100%)

Query: 1   MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
           MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE
Sbjct: 1   MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60

Query: 61  TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGIREDPDV 120
           TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGIREDPDV
Sbjct: 61  TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGIREDPDV 120

Query: 121 CLKAP 125
           CLKAP
Sbjct: 121 CLKAP 125


>gi|4506923 SH2 domain protein 1A isoform 1 [Homo sapiens]
          Length = 128

 Score =  251 bits (642), Expect = 8e-68
 Identities = 125/128 (97%), Positives = 125/128 (97%), Gaps = 3/128 (2%)

Query: 1   MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
           MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE
Sbjct: 1   MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60

Query: 61  TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQ---GIRED 117
           TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQ   GIRED
Sbjct: 61  TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED 120

Query: 118 PDVCLKAP 125
           PDVCLKAP
Sbjct: 121 PDVCLKAP 128


>gi|54792745 SH2 domain containing 1B [Homo sapiens]
          Length = 132

 Score =  108 bits (269), Expect = 1e-24
 Identities = 48/109 (44%), Positives = 77/109 (70%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
           YHG+++++  E LLL  G+DG++LLRDSES+PGV CLCV +   +YTYR+ + + G +  
Sbjct: 6   YHGRLTKQDCETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREKHGYYRI 65

Query: 67  ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGIR 115
           +TA G  K+ F  +K LIS F+KP+QG+V+ L  P+++ S +   +G++
Sbjct: 66  QTAEGSPKQVFPSLKELISKFEKPNQGMVVHLLKPIKRTSPSLRWRGLK 114


>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
           sapiens]
          Length = 1188

 Score = 92.4 bits (228), Expect = 8e-20
 Identities = 43/95 (45%), Positives = 60/95 (63%)

Query: 8   HGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAE 67
           HG I+R   E+LL  TG DGS+L+R SES+   Y LCVLY   +YTYR+   E   ++ +
Sbjct: 7   HGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQ 66

Query: 68  TAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPV 102
            + GV  R+F K+  LI  ++K + G+V  LQYPV
Sbjct: 67  ASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPV 101


>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
           sapiens]
          Length = 1189

 Score = 92.4 bits (228), Expect = 8e-20
 Identities = 43/95 (45%), Positives = 60/95 (63%)

Query: 8   HGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAE 67
           HG I+R   E+LL  TG DGS+L+R SES+   Y LCVLY   +YTYR+   E   ++ +
Sbjct: 7   HGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQ 66

Query: 68  TAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPV 102
            + GV  R+F K+  LI  ++K + G+V  LQYPV
Sbjct: 67  ASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPV 101


>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo
           sapiens]
          Length = 1258

 Score = 86.3 bits (212), Expect = 6e-18
 Identities = 42/97 (43%), Positives = 60/97 (61%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
           YH  +SR   E+LL   G DGS+L+RDSESV G + LCVLY  +++TYR+        + 
Sbjct: 22  YHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLAV 81

Query: 67  ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVE 103
           +T+ GV  R F+ +  LI  + +P+QG+V  L  PVE
Sbjct: 82  QTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVE 118


>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
           [Homo sapiens]
          Length = 1130

 Score = 59.7 bits (143), Expect = 6e-10
 Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 6/100 (6%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
           YHG +SR   E  LL++G++GS+L+R+SES PG   + + Y G +Y YR++    G    
Sbjct: 128 YHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYV 186

Query: 67  ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKS 106
            +     +  F  +  L+        G++  L YP  K++
Sbjct: 187 SS-----ESRFNTLAELVHHHSTVADGLITTLHYPAPKRN 221


>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
           [Homo sapiens]
          Length = 1149

 Score = 59.7 bits (143), Expect = 6e-10
 Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 6/100 (6%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
           YHG +SR   E  LL++G++GS+L+R+SES PG   + + Y G +Y YR++    G    
Sbjct: 147 YHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYV 205

Query: 67  ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKS 106
            +     +  F  +  L+        G++  L YP  K++
Sbjct: 206 SS-----ESRFNTLAELVHHHSTVADGLITTLHYPAPKRN 240


>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
          Length = 1167

 Score = 55.5 bits (132), Expect = 1e-08
 Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 6/98 (6%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
           YHG +SR   E  LL++ ++GS+L+R+SES PG   + + Y G +Y YR++ T  G    
Sbjct: 159 YHGPVSRSAAE-YLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 217

Query: 67  ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
                  +  F  +  L+        G+V  L YP  K
Sbjct: 218 TA-----ESRFSTLAELVHHHSTVADGLVTTLHYPAPK 250


>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
          Length = 1182

 Score = 55.5 bits (132), Expect = 1e-08
 Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 6/98 (6%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
           YHG +SR   E  LL++ ++GS+L+R+SES PG   + + Y G +Y YR++ T  G    
Sbjct: 174 YHGPVSRSAAE-YLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 232

Query: 67  ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
                  +  F  +  L+        G+V  L YP  K
Sbjct: 233 TA-----ESRFSTLAELVHHHSTVADGLVTTLHYPAPK 265


>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
          Length = 542

 Score = 55.5 bits (132), Expect = 1e-08
 Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 6/98 (6%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
           YHG +SR   E  LL++ ++GS+L+R+SES PG   + + Y G +Y YR++ T  G    
Sbjct: 153 YHGPVSRSAAE-YLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 211

Query: 67  ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
                  +  F  +  L+        G+V  L YP  K
Sbjct: 212 TA-----ESRFSTLAELVHHHSTVADGLVTTLHYPAPK 244


>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
          Length = 1064

 Score = 55.5 bits (132), Expect = 1e-08
 Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 6/98 (6%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
           YHG +SR   E  LL++ ++GS+L+R+SES PG   + + Y G +Y YR++ T  G    
Sbjct: 159 YHGPVSRSAAE-YLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 217

Query: 67  ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
                  +  F  +  L+        G+V  L YP  K
Sbjct: 218 TA-----ESRFSTLAELVHHHSTVADGLVTTLHYPAPK 250


>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
          Length = 1146

 Score = 55.5 bits (132), Expect = 1e-08
 Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 6/98 (6%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
           YHG +SR   E  LL++ ++GS+L+R+SES PG   + + Y G +Y YR++ T  G    
Sbjct: 138 YHGPVSRSAAE-YLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 196

Query: 67  ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
                  +  F  +  L+        G+V  L YP  K
Sbjct: 197 TA-----ESRFSTLAELVHHHSTVADGLVTTLHYPAPK 229


>gi|158631203 dual adaptor of phosphotyrosine and
          3-phosphoinositides [Homo sapiens]
          Length = 280

 Score = 50.1 bits (118), Expect = 4e-07
 Identities = 24/53 (45%), Positives = 30/53 (56%)

Query: 7  YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQT 59
          YHG ++R   E LLL+ G DGSYLLRDS    G+Y L V     +  + V  T
Sbjct: 36 YHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYT 88


>gi|205277435 spleen tyrosine kinase isoform 2 [Homo sapiens]
          Length = 612

 Score = 48.9 bits (115), Expect = 1e-06
 Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 7/99 (7%)

Query: 7   YHGKISRETGEKL-LLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWS 65
           +HGKISRE  E++ L+ +  +G +L+R  ++  G Y LC+L+ G +  YR+ + +TG  S
Sbjct: 169 FHGKISREESEQIVLIGSKTNGKFLIRARDN-NGSYALCLLHEGKVLHYRIDKDKTGKLS 227

Query: 66  AETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
                    + F  +  L+  +     G++  L  P +K
Sbjct: 228 IPEG-----KKFDTLWQLVEHYSYKADGLLRVLTVPCQK 261



 Score = 35.8 bits (81), Expect = 0.009
 Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 6/112 (5%)

Query: 7   YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWS 65
           + G I+RE  E  L+  G+ DG YLLR S +  G + L V +    + Y + +   G+++
Sbjct: 16  FFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYA 75

Query: 66  AETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGIRED 117
                    R      +L     +   G+V  L+ P  +    +   G  ED
Sbjct: 76  IAGG-----RTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFED 122


>gi|21361553 spleen tyrosine kinase isoform 1 [Homo sapiens]
          Length = 635

 Score = 48.9 bits (115), Expect = 1e-06
 Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 7/99 (7%)

Query: 7   YHGKISRETGEKL-LLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWS 65
           +HGKISRE  E++ L+ +  +G +L+R  ++  G Y LC+L+ G +  YR+ + +TG  S
Sbjct: 169 FHGKISREESEQIVLIGSKTNGKFLIRARDN-NGSYALCLLHEGKVLHYRIDKDKTGKLS 227

Query: 66  AETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
                    + F  +  L+  +     G++  L  P +K
Sbjct: 228 IPEG-----KKFDTLWQLVEHYSYKADGLLRVLTVPCQK 261



 Score = 35.8 bits (81), Expect = 0.009
 Identities = 28/112 (25%), Positives = 47/112 (41%), Gaps = 6/112 (5%)

Query: 7   YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWS 65
           + G I+RE  E  L+  G+ DG YLLR S +  G + L V +    + Y + +   G+++
Sbjct: 16  FFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYA 75

Query: 66  AETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGIRED 117
                    R      +L     +   G+V  L+ P  +    +   G  ED
Sbjct: 76  IAGG-----RTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFED 122


>gi|4503787 fyn-related kinase [Homo sapiens]
          Length = 505

 Score = 45.8 bits (107), Expect = 8e-06
 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 6/99 (6%)

Query: 7   YHGKISRETGEK-LLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWS 65
           + G I R   EK LL +    GS+L+R+SES  G + L VL    +  YR+ + + G + 
Sbjct: 117 FFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGFF 176

Query: 66  AETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
                   +R F  +   +S + K   G+ + L  P  K
Sbjct: 177 L-----TRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLK 210


>gi|187475373 c-src tyrosine kinase [Homo sapiens]
          Length = 450

 Score = 44.7 bits (104), Expect = 2e-05
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 7/95 (7%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
           +HGKI+RE  E+LL      G +L+R+S + PG Y LCV   G +  YR+       + A
Sbjct: 83  FHGKITREQAERLLYPPET-GLFLVRESTNYPGDYTLCVSCDGKVEHYRI------MYHA 135

Query: 67  ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYP 101
                  + YF  +  L+  +     G+   L  P
Sbjct: 136 SKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKP 170


>gi|4758078 c-src tyrosine kinase [Homo sapiens]
          Length = 450

 Score = 44.7 bits (104), Expect = 2e-05
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 7/95 (7%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
           +HGKI+RE  E+LL      G +L+R+S + PG Y LCV   G +  YR+       + A
Sbjct: 83  FHGKITREQAERLLYPPET-GLFLVRESTNYPGDYTLCVSCDGKVEHYRI------MYHA 135

Query: 67  ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYP 101
                  + YF  +  L+  +     G+   L  P
Sbjct: 136 SKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKP 170


>gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]
          Length = 620

 Score = 44.7 bits (104), Expect = 2e-05
 Identities = 38/117 (32%), Positives = 54/117 (46%), Gaps = 12/117 (10%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGY-------IYTYRVSQT 59
           Y+  ISR+  EKLLL TG +G++++RDS +  G Y + V            I  Y + +T
Sbjct: 240 YNKSISRDKAEKLLLDTGKEGAFMVRDSRTA-GTYTVSVFTKAVVSENNPCIKHYHIKET 298

Query: 60  ETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPV-EKKSSARSTQGIR 115
                    A    K  F  I  LI+  Q    G+V  L+YPV   +  A  T G+R
Sbjct: 299 NDNPKRYYVA---EKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPVTAGLR 352


>gi|48762697 growth factor receptor-bound protein 10 isoform c [Homo
           sapiens]
          Length = 536

 Score = 43.5 bits (101), Expect = 4e-05
 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 1/55 (1%)

Query: 7   YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
           +HG+ISRE   +++   GL DG +LLRDS+S P  + L + +H  I  +++   E
Sbjct: 436 FHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCE 490


>gi|48762695 growth factor receptor-bound protein 10 isoform c [Homo
           sapiens]
          Length = 536

 Score = 43.5 bits (101), Expect = 4e-05
 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 1/55 (1%)

Query: 7   YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
           +HG+ISRE   +++   GL DG +LLRDS+S P  + L + +H  I  +++   E
Sbjct: 436 FHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCE 490


>gi|48762693 growth factor receptor-bound protein 10 isoform b [Homo
           sapiens]
          Length = 548

 Score = 43.5 bits (101), Expect = 4e-05
 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 1/55 (1%)

Query: 7   YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
           +HG+ISRE   +++   GL DG +LLRDS+S P  + L + +H  I  +++   E
Sbjct: 448 FHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCE 502


>gi|48762679 growth factor receptor-bound protein 10 isoform a [Homo
           sapiens]
          Length = 594

 Score = 43.5 bits (101), Expect = 4e-05
 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 1/55 (1%)

Query: 7   YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
           +HG+ISRE   +++   GL DG +LLRDS+S P  + L + +H  I  +++   E
Sbjct: 494 FHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCE 548


>gi|5729856 GRB2-related adaptor protein [Homo sapiens]
          Length = 217

 Score = 42.7 bits (99), Expect = 7e-05
 Identities = 19/58 (32%), Positives = 36/58 (62%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSW 64
           Y G+ISR+  E++L+     G++L+R+SES PG + + V Y   +  ++V +  +G +
Sbjct: 61  YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKY 118


>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score = 42.4 bits (98), Expect = 9e-05
 Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 13/117 (11%)

Query: 7   YHGKISRETGEKLLL-ATGLDGSYLLRDSESVPGVYCLCVLYHG-----YIYTYRVSQTE 60
           Y GKI+R   E+LLL A    G++L+R+SE+  G YCL V          +  Y++ + +
Sbjct: 152 YFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLD 211

Query: 61  TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGIRED 117
           +G +   +     +  F  ++ L++ + K   G+   L       +S   TQG+ +D
Sbjct: 212 SGGFYITS-----RTQFNSLQQLVAYYSKHADGLCHRL--TTVCPTSKPQTQGLAKD 261


>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score = 42.4 bits (98), Expect = 9e-05
 Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 13/117 (11%)

Query: 7   YHGKISRETGEKLLL-ATGLDGSYLLRDSESVPGVYCLCVLYHG-----YIYTYRVSQTE 60
           Y GKI+R   E+LLL A    G++L+R+SE+  G YCL V          +  Y++ + +
Sbjct: 152 YFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLD 211

Query: 61  TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGIRED 117
           +G +   +     +  F  ++ L++ + K   G+   L       +S   TQG+ +D
Sbjct: 212 SGGFYITS-----RTQFNSLQQLVAYYSKHADGLCHRL--TTVCPTSKPQTQGLAKD 261


>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
          Length = 468

 Score = 42.4 bits (98), Expect = 9e-05
 Identities = 20/50 (40%), Positives = 32/50 (64%), Gaps = 2/50 (4%)

Query: 7   YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRV 56
           +HG ISRE  ++LL   G++G+Y+LR+S+  PG Y L + +      YR+
Sbjct: 60  FHGIISREQADELL--GGVEGAYILRESQRQPGCYTLALRFGNQTLNYRL 107


>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
          Length = 459

 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 2/50 (4%)

Query: 7  YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRV 56
          +HG ISRE  ++LL+    +GSYL+R+S+  PG Y L + +      +R+
Sbjct: 50 FHGMISREAADQLLIVA--EGSYLIRESQRQPGTYTLALRFGSQTRNFRL 97


>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
          Length = 433

 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 2/50 (4%)

Query: 7  YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRV 56
          +HG ISRE  ++LL+    +GSYL+R+S+  PG Y L + +      +R+
Sbjct: 50 FHGMISREAADQLLIVA--EGSYLIRESQRQPGTYTLALRFGSQTRNFRL 97


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,869,166
Number of Sequences: 37866
Number of extensions: 189635
Number of successful extensions: 514
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 73
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 401
Number of HSP's gapped (non-prelim): 119
length of query: 125
length of database: 18,247,518
effective HSP length: 90
effective length of query: 35
effective length of database: 14,839,578
effective search space: 519385230
effective search space used: 519385230
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.