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Search of human proteins with 169234778
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169234778 potassium channel tetramerisation domain
containing 17 [Homo sapiens]
(297 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169234778 potassium channel tetramerisation domain containing... 608 e-174
gi|9506651 potassium channel tetramerisation domain containing 5... 304 5e-83
gi|53829365 potassium channel tetramerisation domain containing ... 287 7e-78
gi|46255026 potassium channel tetramerisation domain containing ... 86 5e-17
gi|39753959 potassium channel tetramerisation domain containing ... 84 1e-16
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens] 83 3e-16
gi|169184031 PREDICTED: similar to potassium channel tetramerisa... 76 3e-14
gi|169179790 PREDICTED: similar to potassium channel tetramerisa... 76 3e-14
gi|169180181 PREDICTED: similar to potassium channel tetramerisa... 76 3e-14
gi|146198864 potassium channel tetramerisation domain containing... 69 5e-12
gi|189571693 potassium channel tetramerisation domain containing... 68 1e-11
gi|189571691 potassium channel tetramerisation domain containing... 68 1e-11
gi|71143104 potassium channel tetramerisation domain containing ... 64 2e-10
gi|13994353 potassium channel tetramerisation domain containing ... 62 6e-10
gi|23308551 potassium channel tetramerisation domain containing ... 62 8e-10
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo... 60 2e-09
gi|30578412 potassium channel tetramerisation domain containing ... 59 4e-09
gi|142356950 potassium channel tetramerisation domain containing... 57 3e-08
gi|194018443 potassium channel tetramerisation domain containing... 56 3e-08
gi|194018441 potassium channel tetramerisation domain containing... 56 3e-08
gi|194018439 potassium channel tetramerisation domain containing... 56 3e-08
gi|19923973 potassium channel tetramerisation domain containing ... 54 2e-07
gi|45387953 potassium channel tetramerization domain containing ... 53 3e-07
gi|55926200 potassium channel tetramerisation domain containing ... 53 4e-07
gi|38198663 potassium channel tetramerisation domain containing ... 52 5e-07
gi|218505694 potassium channel tetramerisation domain containing... 50 2e-06
gi|209969708 potassium channel tetramerisation domain containing... 50 2e-06
gi|40217617 potassium channel tetramerisation domain containing ... 50 2e-06
gi|27436996 potassium voltage-gated channel, subfamily G, member... 50 2e-06
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens] 47 3e-05
>gi|169234778 potassium channel tetramerisation domain containing 17
[Homo sapiens]
Length = 297
Score = 608 bits (1568), Expect = e-174
Identities = 297/297 (100%), Positives = 297/297 (100%)
Query: 1 MQTPRPAMRMEAGEAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRL 60
MQTPRPAMRMEAGEAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRL
Sbjct: 1 MQTPRPAMRMEAGEAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRL 60
Query: 61 CQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPL 120
CQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPL
Sbjct: 61 CQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPL 120
Query: 121 IRIIKDRMEEKDYTVTQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSSYNYG 180
IRIIKDRMEEKDYTVTQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSSYNYG
Sbjct: 121 IRIIKDRMEEKDYTVTQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSSYNYG 180
Query: 181 SEDQAEFLCVVSKELHSTPNGLSSESSRKTKSTEEQLEEQQQQEEEVEEVEVEQVQVEAD 240
SEDQAEFLCVVSKELHSTPNGLSSESSRKTKSTEEQLEEQQQQEEEVEEVEVEQVQVEAD
Sbjct: 181 SEDQAEFLCVVSKELHSTPNGLSSESSRKTKSTEEQLEEQQQQEEEVEEVEVEQVQVEAD 240
Query: 241 AQEKGSRPHPLRPEAELAVRASPRPLARPQSCHPCCYKPEAPGCEAPDHLQGLGVPI 297
AQEKGSRPHPLRPEAELAVRASPRPLARPQSCHPCCYKPEAPGCEAPDHLQGLGVPI
Sbjct: 241 AQEKGSRPHPLRPEAELAVRASPRPLARPQSCHPCCYKPEAPGCEAPDHLQGLGVPI 297
>gi|9506651 potassium channel tetramerisation domain containing 5
[Homo sapiens]
Length = 234
Score = 304 bits (779), Expect = 5e-83
Identities = 147/198 (74%), Positives = 171/198 (86%), Gaps = 1/198 (0%)
Query: 20 GAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGE-ELQSDRDETGAYLI 78
GA + G KWVRLNVGGT FLTTRQTLCR+ KSFL RLCQ + +L SD+DETGAYLI
Sbjct: 33 GALAQRPGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLI 92
Query: 79 DRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRMEEKDYTVTQV 138
DRDPTYFGP+LN+LRHGKLV++KD+AEEGVLEEAEFYNI LI+++KD++ E+D +QV
Sbjct: 93 DRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQV 152
Query: 139 PPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSSYNYGSEDQAEFLCVVSKELHST 198
P KHVYRVLQCQEEELTQMVSTMSDGW+FEQLV+IGSSYNYG+EDQAEFLCVVSKELH+T
Sbjct: 153 PVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNT 212
Query: 199 PNGLSSESSRKTKSTEEQ 216
P G +SE S K K +E+
Sbjct: 213 PYGTASEPSEKAKILQER 230
>gi|53829365 potassium channel tetramerisation domain containing 2
[Homo sapiens]
Length = 263
Score = 287 bits (735), Expect = 7e-78
Identities = 144/212 (67%), Positives = 172/212 (81%), Gaps = 6/212 (2%)
Query: 7 AMRMEAGEAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGE-- 64
A +E G PP AGG GG +WVRLNVGGT F+TTRQTL RE KSFL RLC E
Sbjct: 52 AQPLEPGPG-PPERAGG---GGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDP 107
Query: 65 ELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRII 124
EL SD+DETGAYLIDRDPTYFGPILN+LRHGKL++ K++AEEGVLEEAEFYNI L+R++
Sbjct: 108 ELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLV 167
Query: 125 KDRMEEKDYTVTQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSSYNYGSEDQ 184
K+R+ + + +Q P KHVYRVLQCQEEELTQMVSTMSDGW+FEQL++IGSSYNYG+EDQ
Sbjct: 168 KERIRDNENRTSQGPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNEDQ 227
Query: 185 AEFLCVVSKELHSTPNGLSSESSRKTKSTEEQ 216
AEFLCVVS+EL+++ NG+ E S K K +E+
Sbjct: 228 AEFLCVVSRELNNSTNGIVIEPSEKAKILQER 259
>gi|46255026 potassium channel tetramerisation domain containing 3
[Homo sapiens]
Length = 815
Score = 85.5 bits (210), Expect = 5e-17
Identities = 53/103 (51%), Positives = 65/103 (63%), Gaps = 2/103 (1%)
Query: 20 GAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLID 79
G+ AA G G+ V+LNVGGT F T+RQTL SF S L G + + RDETGA ID
Sbjct: 7 GSFPAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGR-ISTLRDETGAIFID 65
Query: 80 RDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIR 122
RDP F PILNFLR +L L + ++ + EAEFY I PL+R
Sbjct: 66 RDPAAFAPILNFLRTKELDL-RGVSINVLRHEAEFYGITPLVR 107
>gi|39753959 potassium channel tetramerisation domain containing 9
[Homo sapiens]
Length = 389
Score = 84.0 bits (206), Expect = 1e-16
Identities = 51/127 (40%), Positives = 74/127 (58%), Gaps = 10/127 (7%)
Query: 14 EAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLC-REQKSFLSRLCQGEELQSDR-D 71
++ PP G G W+ LNVGG F TTR TL +E S L+ + + + + ++ D
Sbjct: 76 DSKPPEGL----LGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQD 131
Query: 72 ETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIR----IIKDR 127
GA+LIDR P YF PILN+LRHG+L+++ + GVLEEA F+ I LI IK+
Sbjct: 132 HRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNS 191
Query: 128 MEEKDYT 134
+D++
Sbjct: 192 QPPEDHS 198
>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
Length = 707
Score = 83.2 bits (204), Expect = 3e-16
Identities = 52/115 (45%), Positives = 68/115 (59%), Gaps = 2/115 (1%)
Query: 15 AAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETG 74
AA A G + G G+ + LNVGG F T+RQTL SF S L G + + +DETG
Sbjct: 3 AAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGR-ISTLKDETG 61
Query: 75 AYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRME 129
A IDRDPT F PILNFLR +L + + +L EA+FY + PL+R ++ R E
Sbjct: 62 AIFIDRDPTVFAPILNFLRTKELD-PRGVHGSSLLHEAQFYGLTPLVRRLQLREE 115
>gi|169184031 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
Length = 261
Score = 76.3 bits (186), Expect = 3e-14
Identities = 45/114 (39%), Positives = 67/114 (58%), Gaps = 6/114 (5%)
Query: 14 EAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLC-REQKSFLSRLCQGEELQSDR-D 71
++ PP G G W+ L+VGG F TT TL +E L+ + + + + ++ D
Sbjct: 76 DSKPPEGL----LGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQD 131
Query: 72 ETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIK 125
GA+LID+ P YF PILN+LRHG+L+++ + GVLEEA F+ I LI +K
Sbjct: 132 HRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLK 185
>gi|169179790 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
Length = 261
Score = 76.3 bits (186), Expect = 3e-14
Identities = 45/114 (39%), Positives = 67/114 (58%), Gaps = 6/114 (5%)
Query: 14 EAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLC-REQKSFLSRLCQGEELQSDR-D 71
++ PP G G W+ L+VGG F TT TL +E L+ + + + + ++ D
Sbjct: 76 DSKPPEGL----LGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQD 131
Query: 72 ETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIK 125
GA+LID+ P YF PILN+LRHG+L+++ + GVLEEA F+ I LI +K
Sbjct: 132 HRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLK 185
>gi|169180181 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
Length = 261
Score = 76.3 bits (186), Expect = 3e-14
Identities = 45/114 (39%), Positives = 67/114 (58%), Gaps = 6/114 (5%)
Query: 14 EAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLC-REQKSFLSRLCQGEELQSDR-D 71
++ PP G G W+ L+VGG F TT TL +E L+ + + + + ++ D
Sbjct: 76 DSKPPEGL----LGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQD 131
Query: 72 ETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIK 125
GA+LID+ P YF PILN+LRHG+L+++ + GVLEEA F+ I LI +K
Sbjct: 132 HRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLK 185
>gi|146198864 potassium channel tetramerisation domain containing 4
[Homo sapiens]
Length = 259
Score = 68.9 bits (167), Expect = 5e-12
Identities = 40/101 (39%), Positives = 60/101 (59%), Gaps = 2/101 (1%)
Query: 35 LNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFLRH 94
LNVGG +++T +QTL + +FL + G+ L D G Y IDRD F +LNFLR+
Sbjct: 37 LNVGGYLYITQKQTLTKYPDTFLEGIVNGKIL-CPFDADGHYFIDRDGLLFRHVLNFLRN 95
Query: 95 GKLVLDKDMAEEGVL-EEAEFYNIGPLIRIIKDRMEEKDYT 134
G+L+L + E +L +EAEF+ + L +K R E++ T
Sbjct: 96 GELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLT 136
>gi|189571693 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 67.8 bits (164), Expect = 1e-11
Identities = 44/105 (41%), Positives = 57/105 (54%), Gaps = 6/105 (5%)
Query: 27 GGWGKW----VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDP 82
G WG V LNVGG ++ T+ TL R S L + G+ + RD G Y IDRD
Sbjct: 4 GDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGD-FPTARDPQGNYFIDRDG 62
Query: 83 TYFGPILNFLRHGKLVLDKDMAEEGVL-EEAEFYNIGPLIRIIKD 126
F +LNFLR +L L D E +L +EA+FY I PLI+ + D
Sbjct: 63 PLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLND 107
>gi|189571691 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 67.8 bits (164), Expect = 1e-11
Identities = 44/105 (41%), Positives = 57/105 (54%), Gaps = 6/105 (5%)
Query: 27 GGWGKW----VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDP 82
G WG V LNVGG ++ T+ TL R S L + G+ + RD G Y IDRD
Sbjct: 4 GDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGD-FPTARDPQGNYFIDRDG 62
Query: 83 TYFGPILNFLRHGKLVLDKDMAEEGVL-EEAEFYNIGPLIRIIKD 126
F +LNFLR +L L D E +L +EA+FY I PLI+ + D
Sbjct: 63 PLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLND 107
>gi|71143104 potassium channel tetramerisation domain containing 21
[Homo sapiens]
Length = 260
Score = 63.5 bits (153), Expect = 2e-10
Identities = 39/99 (39%), Positives = 55/99 (55%), Gaps = 2/99 (2%)
Query: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
+ LNVGG ++ T+ TL S L + G+ + + RD G IDRD F ILNFL
Sbjct: 5 ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGK-MPTKRDSQGNCFIDRDGKVFRYILNFL 63
Query: 93 RHGKLVLDKDMAEEGVL-EEAEFYNIGPLIRIIKDRMEE 130
R L L +D E G+L EA+FY + PLI ++++ E
Sbjct: 64 RTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVE 102
>gi|13994353 potassium channel tetramerisation domain containing 10
[Homo sapiens]
Length = 313
Score = 62.0 bits (149), Expect = 6e-10
Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)
Query: 31 KWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILN 90
K+V+LNVGG ++ TT QTL + Q + L + G ++ D G LIDR +FG ILN
Sbjct: 32 KYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSG-RMEVLTDSEGWILIDRCGKHFGTILN 89
Query: 91 FLRHGKLVLDKDMAE-EGVLEEAEFYNIGPLIRIIKDRMEEKD 132
+LR G + L + E E +L EA++Y + L+ + ++ KD
Sbjct: 90 YLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKD 132
>gi|23308551 potassium channel tetramerisation domain containing 7
[Homo sapiens]
Length = 289
Score = 61.6 bits (148), Expect = 8e-10
Identities = 39/105 (37%), Positives = 55/105 (52%), Gaps = 3/105 (2%)
Query: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
V LN+GG F T TL + + L+ + G D G Y IDRD T+FG +LNFL
Sbjct: 53 VPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHY-IPTDSEGRYFIDRDGTHFGDVLNFL 111
Query: 93 RHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRMEEKDYTVTQ 137
R G L + + V +EA++Y IGPL+ +++ K V Q
Sbjct: 112 RSGDLPPRERV--RAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQ 154
>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
sapiens]
Length = 316
Score = 60.5 bits (145), Expect = 2e-09
Identities = 37/117 (31%), Positives = 66/117 (56%), Gaps = 3/117 (2%)
Query: 16 APPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGA 75
A P +G + G K+V+LNVGG+++ TT + L R + E+ +D++ G
Sbjct: 13 AKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGRMEVLTDKE--GW 70
Query: 76 YLIDRDPTYFGPILNFLRHGKLVLDKDMAE-EGVLEEAEFYNIGPLIRIIKDRMEEK 131
LIDR +FG ILN+LR + L ++ E + ++ EA++Y I L+ + + +++K
Sbjct: 71 ILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDK 127
>gi|30578412 potassium channel tetramerisation domain containing 13
[Homo sapiens]
Length = 329
Score = 59.3 bits (142), Expect = 4e-09
Identities = 50/161 (31%), Positives = 81/161 (50%), Gaps = 11/161 (6%)
Query: 1 MQTPRPAMRMEAGEAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRL 60
++ P+P+ G PA G + K+V+LNVGG++ TT +TL Q + L +
Sbjct: 16 LEAPKPS-----GLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTG-QDTMLKAM 69
Query: 61 CQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEG-VLEEAEFYNIGP 119
G ++ D G LIDR +FG ILN+LR G + L + E G +L EA +Y +
Sbjct: 70 FSGR-VEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQG 128
Query: 120 LIRIIKDRMEEKDYTVTQVPPKHVYRVLQCQEEELTQMVST 160
LI + +++K T++ P + ++ EE + ST
Sbjct: 129 LIEDCQLALQQKRETLS---PLCLIPMVTSPREEQQLLAST 166
>gi|142356950 potassium channel tetramerisation domain containing 14
[Homo sapiens]
Length = 255
Score = 56.6 bits (135), Expect = 3e-08
Identities = 37/94 (39%), Positives = 54/94 (57%), Gaps = 4/94 (4%)
Query: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
V LNVGG TT TL + S L+ + ++ D G + IDR TYF PIL++L
Sbjct: 35 VELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLA-KASTDAEGRFFIDRPSTYFRPILDYL 93
Query: 93 RHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKD 126
R G+ V + + E V EA+FY I PL+++++D
Sbjct: 94 RTGQ-VPTQHIPE--VYREAQFYEIKPLVKLLED 124
>gi|194018443 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 56.2 bits (134), Expect = 3e-08
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 19/152 (12%)
Query: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
V ++VGG ++ ++ TL + S +SRL G E Y IDRD F +L+FL
Sbjct: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117
Query: 93 RHGKLVLDKDMAEEGVL-EEAEFYNIGPLIRIIKDRMEEK---------DYTVTQVPPKH 142
R KL+L D + +L EEA +Y + P++R ++ +E+ D V +V P
Sbjct: 118 RTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDL 177
Query: 143 VYRVLQCQEEELTQ---------MVSTMSDGW 165
R+ E+ L + M ++++ GW
Sbjct: 178 GERIALSGEKALIEEVFPETGDVMCNSVNAGW 209
>gi|194018441 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 56.2 bits (134), Expect = 3e-08
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 19/152 (12%)
Query: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
V ++VGG ++ ++ TL + S +SRL G E Y IDRD F +L+FL
Sbjct: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117
Query: 93 RHGKLVLDKDMAEEGVL-EEAEFYNIGPLIRIIKDRMEEK---------DYTVTQVPPKH 142
R KL+L D + +L EEA +Y + P++R ++ +E+ D V +V P
Sbjct: 118 RTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDL 177
Query: 143 VYRVLQCQEEELTQ---------MVSTMSDGW 165
R+ E+ L + M ++++ GW
Sbjct: 178 GERIALSGEKALIEEVFPETGDVMCNSVNAGW 209
>gi|194018439 potassium channel tetramerisation domain containing 15
isoform 1 [Homo sapiens]
Length = 234
Score = 56.2 bits (134), Expect = 3e-08
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 19/152 (12%)
Query: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
V ++VGG ++ ++ TL + S +SRL G E Y IDRD F +L+FL
Sbjct: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117
Query: 93 RHGKLVLDKDMAEEGVL-EEAEFYNIGPLIRIIKDRMEEK---------DYTVTQVPPKH 142
R KL+L D + +L EEA +Y + P++R ++ +E+ D V +V P
Sbjct: 118 RTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRSRACDCLVVRVTPDL 177
Query: 143 VYRVLQCQEEELTQ---------MVSTMSDGW 165
R+ E+ L + M ++++ GW
Sbjct: 178 GERIALSGEKALIEEVFPETGDVMCNSVNAGW 209
>gi|19923973 potassium channel tetramerisation domain containing 12
[Homo sapiens]
Length = 325
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 11/117 (9%)
Query: 17 PPAGAGGRAAGG---------WGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQ 67
P G GG +G + V LNVGG V++T R T+ S L R+ ++ Q
Sbjct: 11 PNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQ 70
Query: 68 S-DRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLE-EAEFYNIGPLIR 122
RD G + +DRD F IL++LR +LVL E L+ EAE++ + L+R
Sbjct: 71 ELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVR 127
>gi|45387953 potassium channel tetramerization domain containing 18
[Homo sapiens]
Length = 426
Score = 53.1 bits (126), Expect = 3e-07
Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 3/86 (3%)
Query: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
+RLNVGG ++ R++LCR + S L+ + G DE+GA +IDRD F +L++L
Sbjct: 14 LRLNVGGCIYTARRESLCRFKDSMLASMFSG-RFPLKTDESGACVIDRDGRLFKYLLDYL 72
Query: 93 RHGKLVLDKD-MAEEGVLEEAEFYNI 117
HG++ + D + EEA+++ I
Sbjct: 73 -HGEVQIPTDEQTRIALQEEADYFGI 97
>gi|55926200 potassium channel tetramerisation domain containing 16
[Homo sapiens]
Length = 428
Score = 52.8 bits (125), Expect = 4e-07
Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 18 PAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSD---RDETG 74
P G + + V LNVGG V+ T TL S L ++ + ++ +D G
Sbjct: 12 PREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKG 71
Query: 75 AYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLE-EAEFYNIGPLIRII 124
+ IDRD F IL++LR ++VL E+G L+ EAE++ + L++++
Sbjct: 72 RFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
>gi|38198663 potassium channel tetramerisation domain containing 8
[Homo sapiens]
Length = 473
Score = 52.4 bits (124), Expect = 5e-07
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 13/140 (9%)
Query: 6 PAMRMEAGEAAPPAGA----GGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLC 61
P M + ++P A A G A + + V LNVGG V++T TL S L+ +
Sbjct: 15 PISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMF 74
Query: 62 QGEELQSD--------RDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAE-EGVLEEA 112
+ RD + IDRD F +L++LR +L L + E E +L EA
Sbjct: 75 SPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREA 134
Query: 113 EFYNIGPLIRIIKDRMEEKD 132
E++ + L++++ ++ +++
Sbjct: 135 EYFQLTDLVKLLSPKVTKQN 154
>gi|218505694 potassium channel tetramerisation domain containing 1
isoform b [Homo sapiens]
Length = 865
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
Query: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
V ++VGG ++ ++ TL + +S + RL G E Y IDRD F ILNFL
Sbjct: 640 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 699
Query: 93 RHGKLVLDKDMAEEGVL-EEAEFYNIGPLI 121
R KL++ D + +L EEA+++ + P++
Sbjct: 700 RTSKLLIPDDFKDYTLLYEEAKYFQLQPML 729
Score = 33.5 bits (75), Expect = 0.23
Identities = 23/97 (23%), Positives = 40/97 (41%), Gaps = 15/97 (15%)
Query: 201 GLSSESSRKTKSTEEQLEEQQQQEEEVEEVEV--------------EQVQVEADAQEKG- 245
G SR + + EE++++E+E++EV++ E+ + E + +E G
Sbjct: 40 GRGRRHSRPHYCSAGEEEEEEEEEDEIQEVQITGDEEEEEDGGGGLEEDEEEEEEEEMGL 99
Query: 246 SRPHPLRPEAELAVRASPRPLARPQSCHPCCYKPEAP 282
PL PE P P+ +PEAP
Sbjct: 100 DWDEPLEPEDSAGEELEPEPVHMINMDQSAALEPEAP 136
>gi|209969708 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
Query: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
V ++VGG ++ ++ TL + +S + RL G E Y IDRD F ILNFL
Sbjct: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 91
Query: 93 RHGKLVLDKDMAEEGVL-EEAEFYNIGPLI 121
R KL++ D + +L EEA+++ + P++
Sbjct: 92 RTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121
>gi|40217617 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
Query: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
V ++VGG ++ ++ TL + +S + RL G E Y IDRD F ILNFL
Sbjct: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 91
Query: 93 RHGKLVLDKDMAEEGVL-EEAEFYNIGPLI 121
R KL++ D + +L EEA+++ + P++
Sbjct: 92 RTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121
>gi|27436996 potassium voltage-gated channel, subfamily G, member 4
[Homo sapiens]
Length = 519
Score = 50.1 bits (118), Expect = 2e-06
Identities = 48/144 (33%), Positives = 69/144 (47%), Gaps = 11/144 (7%)
Query: 31 KWVRLNVGGTVFLTTRQTLCREQKSFLS--RLCQGEE----LQSDRDETGA-YLIDRDPT 83
K + +NVGG +L TL R S LS RLC+ E L D DE + DR P+
Sbjct: 59 KEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPS 118
Query: 84 YFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNI--GPLIRIIKDRMEEKDYTVTQVPPK 141
FG I++FL GKLVL ++M EE ++ I L R ++ K + ++
Sbjct: 119 AFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKL 178
Query: 142 HVYRVLQCQEEELTQMVSTMSDGW 165
H VL+ Q E T+ ++ S W
Sbjct: 179 HREDVLRQQRE--TRRPASHSSRW 200
>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
Length = 229
Score = 46.6 bits (109), Expect = 3e-05
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Query: 33 VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92
V LNVGG +F T T+ + S L+R+ G + Q + G +DRD F IL+FL
Sbjct: 7 VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRD-QEFKMVGGQIFVDRDGDLFSFILDFL 65
Query: 93 RHGKLVLDKDMAEEGVLE-EAEFYNIGPLIRII 124
R +L+L + ++ L+ EA FY + L+ ++
Sbjct: 66 RTHQLLLPTEFSDYLRLQREALFYELRSLVDLL 98
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,295,046
Number of Sequences: 37866
Number of extensions: 674115
Number of successful extensions: 10105
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 291
Number of HSP's successfully gapped in prelim test: 266
Number of HSP's that attempted gapping in prelim test: 6129
Number of HSP's gapped (non-prelim): 2699
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.