Guide to the Human Genome
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Search of human proteins with 169217659

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169217659 PREDICTED: similar to ectonucleotide
pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
         (542 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169217659 PREDICTED: similar to ectonucleotide pyrophosphatas...  1134   0.0  
gi|169167316 PREDICTED: similar to ectonucleotide pyrophosphatas...  1134   0.0  
gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatas...   318   6e-87
gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [...   176   5e-44
gi|239750115 PREDICTED: similar to hCG2042391 [Homo sapiens]          169   6e-42
gi|169209673 PREDICTED: similar to hCG2042391 [Homo sapiens]          154   3e-37
gi|169210658 PREDICTED: similar to hCG2042391 [Homo sapiens]          154   3e-37
gi|169210188 PREDICTED: similar to hCG2042391 [Homo sapiens]          154   3e-37
gi|239743493 PREDICTED: hypothetical protein XP_002342862 [Homo ...   148   1e-35
gi|239743501 PREDICTED: similar to hCG2042391 [Homo sapiens]          146   5e-35
gi|239758137 PREDICTED: hypothetical protein [Homo sapiens]           136   4e-32
gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (...    85   1e-16
gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4 (p...    84   3e-16
gi|212549593 hypothetical protein LOC653333 [Homo sapiens]             63   6e-10
gi|134133220 hypothetical protein LOC85002 [Homo sapiens]              63   6e-10
gi|42475946 hypothetical protein LOC196483 isoform 2 [Homo sapiens]    62   1e-09
gi|42476337 hypothetical protein LOC196483 isoform 1 [Homo sapiens]    62   1e-09
gi|153251796 hypothetical protein LOC55199 isoform 1 [Homo sapiens]    56   1e-07
gi|153251811 hypothetical protein LOC55199 isoform 3 [Homo sapiens]    56   1e-07
gi|24211015 hypothetical protein LOC55199 isoform 2 [Homo sapiens]     56   1e-07
gi|239754822 PREDICTED: hypothetical protein LOC653333 [Homo sap...    55   1e-07
gi|223633935 hypothetical protein LOC254427 [Homo sapiens]             55   2e-07
gi|223941923 OTU domain containing 1 [Homo sapiens]                    51   3e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    50   4e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    50   4e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    50   4e-06
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         49   9e-06
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    47   3e-05
gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [...    47   4e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    46   8e-05

>gi|169217659 PREDICTED: similar to ectonucleotide
           pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
          Length = 542

 Score = 1134 bits (2932), Expect = 0.0
 Identities = 542/542 (100%), Positives = 542/542 (100%)

Query: 1   MPLDWGTDIDNSSFADCEKEGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDF 60
           MPLDWGTDIDNSSFADCEKEGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDF
Sbjct: 1   MPLDWGTDIDNSSFADCEKEGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDF 60

Query: 61  VTLCYREPDNVGHRFGPEAENRKLMIQQIGRTIGVIITRDHGVTTEKKRPNVNKIPLSNY 120
           VTLCYREPDNVGHRFGPEAENRKLMIQQIGRTIGVIITRDHGVTTEKKRPNVNKIPLSNY
Sbjct: 61  VTLCYREPDNVGHRFGPEAENRKLMIQQIGRTIGVIITRDHGVTTEKKRPNVNKIPLSNY 120

Query: 121 IKFRDWVKFDIVGYGGFGMPLPKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHDR 180
           IKFRDWVKFDIVGYGGFGMPLPKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHDR
Sbjct: 121 IKFRDWVKFDIVGYGGFGMPLPKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHDR 180

Query: 181 VLPIVMYANSGYTINGAENPLGQCLSLNPLLILSTCLLCSAERRNCESAYVSPRPDPTIP 240
           VLPIVMYANSGYTINGAENPLGQCLSLNPLLILSTCLLCSAERRNCESAYVSPRPDPTIP
Sbjct: 181 VLPIVMYANSGYTINGAENPLGQCLSLNPLLILSTCLLCSAERRNCESAYVSPRPDPTIP 240

Query: 241 GTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAV 300
           GTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAV
Sbjct: 241 GTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAV 300

Query: 301 CYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAPGTANLDS 360
           CYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAPGTANLDS
Sbjct: 301 CYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAPGTANLDS 360

Query: 361 PQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEE 420
           PQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEE
Sbjct: 361 PQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEE 420

Query: 421 NAGTELWLQGFERRFLAARSLRSFPWQVAGGASGEARGGRGSPGADGMGLGAETPGAPAT 480
           NAGTELWLQGFERRFLAARSLRSFPWQVAGGASGEARGGRGSPGADGMGLGAETPGAPAT
Sbjct: 421 NAGTELWLQGFERRFLAARSLRSFPWQVAGGASGEARGGRGSPGADGMGLGAETPGAPAT 480

Query: 481 CVPGLSPVRAARPGPRPWGLARVARTPSAPRAGGGSWGRLHRPGGQTRVRCGAQFTIIFT 540
           CVPGLSPVRAARPGPRPWGLARVARTPSAPRAGGGSWGRLHRPGGQTRVRCGAQFTIIFT
Sbjct: 481 CVPGLSPVRAARPGPRPWGLARVARTPSAPRAGGGSWGRLHRPGGQTRVRCGAQFTIIFT 540

Query: 541 TF 542
           TF
Sbjct: 541 TF 542


>gi|169167316 PREDICTED: similar to ectonucleotide
           pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
          Length = 542

 Score = 1134 bits (2932), Expect = 0.0
 Identities = 542/542 (100%), Positives = 542/542 (100%)

Query: 1   MPLDWGTDIDNSSFADCEKEGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDF 60
           MPLDWGTDIDNSSFADCEKEGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDF
Sbjct: 1   MPLDWGTDIDNSSFADCEKEGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDF 60

Query: 61  VTLCYREPDNVGHRFGPEAENRKLMIQQIGRTIGVIITRDHGVTTEKKRPNVNKIPLSNY 120
           VTLCYREPDNVGHRFGPEAENRKLMIQQIGRTIGVIITRDHGVTTEKKRPNVNKIPLSNY
Sbjct: 61  VTLCYREPDNVGHRFGPEAENRKLMIQQIGRTIGVIITRDHGVTTEKKRPNVNKIPLSNY 120

Query: 121 IKFRDWVKFDIVGYGGFGMPLPKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHDR 180
           IKFRDWVKFDIVGYGGFGMPLPKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHDR
Sbjct: 121 IKFRDWVKFDIVGYGGFGMPLPKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHDR 180

Query: 181 VLPIVMYANSGYTINGAENPLGQCLSLNPLLILSTCLLCSAERRNCESAYVSPRPDPTIP 240
           VLPIVMYANSGYTINGAENPLGQCLSLNPLLILSTCLLCSAERRNCESAYVSPRPDPTIP
Sbjct: 181 VLPIVMYANSGYTINGAENPLGQCLSLNPLLILSTCLLCSAERRNCESAYVSPRPDPTIP 240

Query: 241 GTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAV 300
           GTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAV
Sbjct: 241 GTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAV 300

Query: 301 CYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAPGTANLDS 360
           CYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAPGTANLDS
Sbjct: 301 CYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAPGTANLDS 360

Query: 361 PQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEE 420
           PQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEE
Sbjct: 361 PQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEE 420

Query: 421 NAGTELWLQGFERRFLAARSLRSFPWQVAGGASGEARGGRGSPGADGMGLGAETPGAPAT 480
           NAGTELWLQGFERRFLAARSLRSFPWQVAGGASGEARGGRGSPGADGMGLGAETPGAPAT
Sbjct: 421 NAGTELWLQGFERRFLAARSLRSFPWQVAGGASGEARGGRGSPGADGMGLGAETPGAPAT 480

Query: 481 CVPGLSPVRAARPGPRPWGLARVARTPSAPRAGGGSWGRLHRPGGQTRVRCGAQFTIIFT 540
           CVPGLSPVRAARPGPRPWGLARVARTPSAPRAGGGSWGRLHRPGGQTRVRCGAQFTIIFT
Sbjct: 481 CVPGLSPVRAARPGPRPWGLARVARTPSAPRAGGGSWGRLHRPGGQTRVRCGAQFTIIFT 540

Query: 541 TF 542
           TF
Sbjct: 541 TF 542


>gi|239755573 PREDICTED: similar to ectonucleotide
           pyrophosphatase/phosphodiesterase 5 (putative function)
           [Homo sapiens]
          Length = 661

 Score =  318 bits (816), Expect = 6e-87
 Identities = 164/231 (70%), Positives = 173/231 (74%), Gaps = 46/231 (19%)

Query: 8   DIDNSSFADCEK-------------------------------EGEAVKRSLVESYTHPN 36
           D+DNSSFADCEK                               EGEAVKRSLVESYTH N
Sbjct: 198 DVDNSSFADCEKGMRNGPDGIFLLYVKGKKAASSHYSRGGAKYEGEAVKRSLVESYTHQN 257

Query: 37  SNETERRENIDTIMNWFTKEDFDFVTLCYREPDNVGHRFGPEAENRKLMIQQIGRTIG-- 94
           SNETE+RENIDT+MN FTKEDFDFVTL YR+PDNVGHRF PEAENRKLMIQQ+ RTI   
Sbjct: 258 SNETEQRENIDTVMNCFTKEDFDFVTLYYRQPDNVGHRFKPEAENRKLMIQQLDRTIWYL 317

Query: 95  -------------VIITRDHGVTTEKKRPNVNKIPLSNYIKFRDWVKFDIVGYGGFGMPL 141
                        VIIT DHG+ T KKRPNVNKI LSNYIKFRDWVKFDIVGYGGFG+PL
Sbjct: 318 VGATEKHSLQSPQVIITXDHGMMTVKKRPNVNKIXLSNYIKFRDWVKFDIVGYGGFGLPL 377

Query: 142 PKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHDRVLPIVMYANSGY 192
           PK GQEEALYQALKNA+PHLHIYKKEEFPEHFH+AKHDRVLPIVMYANS Y
Sbjct: 378 PKLGQEEALYQALKNAHPHLHIYKKEEFPEHFHLAKHDRVLPIVMYANSSY 428



 Score =  120 bits (302), Expect = 2e-27
 Identities = 69/109 (63%), Positives = 69/109 (63%), Gaps = 18/109 (16%)

Query: 223 RRNCESAYVSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGP 282
           RRNCESAYV PRPDPTIPGTL LTGPASRAPNPDSAPPK      AP P     G  P P
Sbjct: 563 RRNCESAYVGPRPDPTIPGTLALTGPASRAPNPDSAPPK------APDP-----GARPWP 611

Query: 283 SSNPPQLR-------LPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCP 324
               P  R         ES  RLA CYDIVNAPP PRLLSPS GL   P
Sbjct: 612 RVGRPWARSWACLKPSAESEQRLATCYDIVNAPPWPRLLSPSPGLPLAP 660


>gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7
           [Homo sapiens]
          Length = 458

 Score =  176 bits (446), Expect = 5e-44
 Identities = 94/200 (47%), Positives = 125/200 (62%), Gaps = 24/200 (12%)

Query: 20  EGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 79
           +G AV RS  E   H   NETE R NIDT+M WFT+ED D VTL + EPD+ GHR+GPE+
Sbjct: 150 QGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDSTGHRYGPES 209

Query: 80  ENRKLMIQQIGRTIG----------------VIITRDHGVTTEKKRP----NVNKIPLSN 119
             R+ M++Q+ RT+G                +IIT DHG+TT  KR       +K P   
Sbjct: 210 PERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFP--- 266

Query: 120 YIKFRDWVKFDIVGYGGFGMPLPKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHD 179
              FRD ++F+++ YG  GM LPK G+ E +Y ALK+A+P LH+YKKE FPE FH A + 
Sbjct: 267 NFTFRD-IEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNP 325

Query: 180 RVLPIVMYANSGYTINGAEN 199
           RV P++MY++ GY I+G  N
Sbjct: 326 RVTPLLMYSDLGYVIHGRIN 345


>gi|239750115 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 149

 Score =  169 bits (428), Expect = 6e-42
 Identities = 85/128 (66%), Positives = 90/128 (70%), Gaps = 31/128 (24%)

Query: 1   MPLDWGTDIDNSSFADCEK-------------------------------EGEAVKRSLV 29
           M LDWGTD+DNSSFADCEK                               EGEAVKR LV
Sbjct: 1   MSLDWGTDVDNSSFADCEKGMRNGPEGIFFLYLQWNKAASSHYSRGGAKYEGEAVKRCLV 60

Query: 30  ESYTHPNSNETERRENIDTIMNWFTKEDFDFVTLCYREPDNVGHRFGPEAENRKLMIQQI 89
           ESYTHPNSNETERRENIDT+MNWFTKEDFD VTLCYREPDNV HRF PEAENRKLMIQQ+
Sbjct: 61  ESYTHPNSNETERRENIDTVMNWFTKEDFDIVTLCYREPDNVRHRFRPEAENRKLMIQQL 120

Query: 90  GRTIGVII 97
            RTIG ++
Sbjct: 121 DRTIGYLV 128


>gi|169209673 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 129

 Score =  154 bits (388), Expect = 3e-37
 Identities = 71/78 (91%), Positives = 75/78 (96%)

Query: 20  EGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 79
           +GEAVKRSLVESYTHPNSNETE RENIDT+MNWFTKEDFDFVTLCYREPDNVGHRFGPEA
Sbjct: 31  DGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 90

Query: 80  ENRKLMIQQIGRTIGVII 97
           ENRKLMIQQI RTIG ++
Sbjct: 91  ENRKLMIQQIDRTIGYLV 108


>gi|169210658 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 129

 Score =  154 bits (388), Expect = 3e-37
 Identities = 71/78 (91%), Positives = 75/78 (96%)

Query: 20  EGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 79
           +GEAVKRSLVESYTHPNSNETE RENIDT+MNWFTKEDFDFVTLCYREPDNVGHRFGPEA
Sbjct: 31  DGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 90

Query: 80  ENRKLMIQQIGRTIGVII 97
           ENRKLMIQQI RTIG ++
Sbjct: 91  ENRKLMIQQIDRTIGYLV 108


>gi|169210188 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 129

 Score =  154 bits (388), Expect = 3e-37
 Identities = 71/78 (91%), Positives = 75/78 (96%)

Query: 20  EGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 79
           +GEAVKRSLVESYTHPNSNETE RENIDT+MNWFTKEDFDFVTLCYREPDNVGHRFGPEA
Sbjct: 31  DGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 90

Query: 80  ENRKLMIQQIGRTIGVII 97
           ENRKLMIQQI RTIG ++
Sbjct: 91  ENRKLMIQQIDRTIGYLV 108


>gi|239743493 PREDICTED: hypothetical protein XP_002342862 [Homo
           sapiens]
          Length = 169

 Score =  148 bits (374), Expect = 1e-35
 Identities = 68/78 (87%), Positives = 74/78 (94%)

Query: 20  EGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 79
           EGEAVK SLV+SYTHP+SNETER+ENIDT+MNWFTKEDFDFVTLCYREPDNVGHRFGPEA
Sbjct: 71  EGEAVKWSLVDSYTHPSSNETERKENIDTVMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 130

Query: 80  ENRKLMIQQIGRTIGVII 97
           E RKLMIQQI RTIG ++
Sbjct: 131 EKRKLMIQQIDRTIGYLV 148


>gi|239743501 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 169

 Score =  146 bits (368), Expect = 5e-35
 Identities = 67/78 (85%), Positives = 73/78 (93%)

Query: 20  EGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 79
           EGEAVK SLV+SYTHP+SNETER+ENID +MNWFTKEDFDFVTLCYREPDNVGHRFGPEA
Sbjct: 71  EGEAVKWSLVDSYTHPSSNETERKENIDIVMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 130

Query: 80  ENRKLMIQQIGRTIGVII 97
           E RKLMIQQI RTIG ++
Sbjct: 131 EKRKLMIQQIDRTIGYLV 148


>gi|239758137 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 89

 Score =  136 bits (343), Expect = 4e-32
 Identities = 69/88 (78%), Positives = 71/88 (80%), Gaps = 6/88 (6%)

Query: 393 PPPLQSRPGFLQVSRQRCGSAHVMAPEENAGTELWLQGFERRFLAARSLRSFPWQVAGGA 452
           P  L+  PG        CG AHVMAPEENAGTEL LQGFERRFLA R+LRSFPWQV GGA
Sbjct: 8   PQTLRRSPG------NGCGLAHVMAPEENAGTELLLQGFERRFLAVRTLRSFPWQVGGGA 61

Query: 453 SGEARGGRGSPGADGMGLGAETPGAPAT 480
           SGEARGGRGSPGADGMGL AETPGAPAT
Sbjct: 62  SGEARGGRGSPGADGMGLRAETPGAPAT 89


>gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5
           (putative function) [Homo sapiens]
          Length = 477

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 53/177 (29%), Positives = 92/177 (51%), Gaps = 23/177 (12%)

Query: 35  PNSNETERRENIDTIMNWFT-KEDFDFVTLCYREPDNVGHRFGPEAE---------NRKL 84
           P +      + +  I+ WFT KE  +   L + +PD++GH  GP++          ++KL
Sbjct: 156 PYNESVSFEDRVAKIIEWFTSKEPINLGLLYWEDPDDMGHHLGPDSPLMGPVISDIDKKL 215

Query: 85  --MIQQIGR-----TIGVIITRDHGVTTEKKRPNVNKIPLSNYIKFRDWVKFDIVGYGGF 137
             +IQ + +     T+ +IIT DHG+T   +      I L  Y+   D   + ++     
Sbjct: 216 GYLIQMLKKAKLWNTLNLIITSDHGMTQCSEE---RLIELDQYL---DKDHYTLIDQSPV 269

Query: 138 GMPLPKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHDRVLPIVMYANSGYTI 194
              LPK G+ + +Y+AL +A+P+L +YKKE+ PE +H   + R+ PI+  A+ G+ I
Sbjct: 270 AAILPKEGKFDEVYEALTHAHPNLTVYKKEDVPERWHYKYNSRIQPIIAVADEGWHI 326


>gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4
           (putative function) [Homo sapiens]
          Length = 453

 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 58/195 (29%), Positives = 91/195 (46%), Gaps = 28/195 (14%)

Query: 29  VESYTHPNSNETERRENIDTIMNWFTKED--FDFVTLCYREPDNVGHRFGPE-AENRKLM 85
           + SY    ++     E ++ I  W    +    F TL + EPD  GH++GPE  EN   +
Sbjct: 147 ISSYFMNYNSSVSFEERLNNITMWLNNSNPPVTFATLYWEEPDASGHKYGPEDKENMSRV 206

Query: 86  IQQIGRTIG----------------VIITRDHGVTTEKKRPNVNKIPLSNYIKFRDWVKF 129
           +++I   IG                VIIT DHG+T        ++  L N     D   +
Sbjct: 207 LKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMT------QCSQDRLINLDSCIDHSYY 260

Query: 130 DIVGYGGFGMPLPKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHDRVLPIVMYAN 189
            ++        LPK  + E +Y  LKN  PH+++Y KE+ P  F+   +DR+ PI++ A+
Sbjct: 261 TLIDLSPVAAILPKINRTE-VYNKLKNCSPHMNVYLKEDIPNRFYYQHNDRIQPIILVAD 319

Query: 190 SGYTI--NGAENPLG 202
            G+TI  N +   LG
Sbjct: 320 EGWTIVLNESSQKLG 334


>gi|212549593 hypothetical protein LOC653333 [Homo sapiens]
          Length = 330

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 29/32 (90%), Positives = 30/32 (93%)

Query: 416 MAPEENAGTELWLQGFERRFLAARSLRSFPWQ 447
           MAPEENAGTEL LQGFERRFLA R+LRSFPWQ
Sbjct: 1   MAPEENAGTELLLQGFERRFLAVRTLRSFPWQ 32


>gi|134133220 hypothetical protein LOC85002 [Homo sapiens]
          Length = 296

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 29/32 (90%), Positives = 30/32 (93%)

Query: 416 MAPEENAGTELWLQGFERRFLAARSLRSFPWQ 447
           MAPEENAGTEL LQGFERRFLA R+LRSFPWQ
Sbjct: 1   MAPEENAGTELLLQGFERRFLAVRTLRSFPWQ 32


>gi|42475946 hypothetical protein LOC196483 isoform 2 [Homo sapiens]
          Length = 296

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 29/32 (90%), Positives = 30/32 (93%)

Query: 416 MAPEENAGTELWLQGFERRFLAARSLRSFPWQ 447
           MAPEENAGTEL LQ FERRFLAAR+LRSFPWQ
Sbjct: 1   MAPEENAGTELLLQSFERRFLAARTLRSFPWQ 32


>gi|42476337 hypothetical protein LOC196483 isoform 1 [Homo sapiens]
          Length = 330

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 29/32 (90%), Positives = 30/32 (93%)

Query: 416 MAPEENAGTELWLQGFERRFLAARSLRSFPWQ 447
           MAPEENAGTEL LQ FERRFLAAR+LRSFPWQ
Sbjct: 1   MAPEENAGTELLLQSFERRFLAARTLRSFPWQ 32


>gi|153251796 hypothetical protein LOC55199 isoform 1 [Homo sapiens]
          Length = 165

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 26/32 (81%), Positives = 29/32 (90%)

Query: 416 MAPEENAGTELWLQGFERRFLAARSLRSFPWQ 447
           MAPEENAG+EL LQ F+RRFLAAR+LRSF WQ
Sbjct: 1   MAPEENAGSELLLQSFKRRFLAARALRSFRWQ 32


>gi|153251811 hypothetical protein LOC55199 isoform 3 [Homo sapiens]
          Length = 158

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 26/32 (81%), Positives = 29/32 (90%)

Query: 416 MAPEENAGTELWLQGFERRFLAARSLRSFPWQ 447
           MAPEENAG+EL LQ F+RRFLAAR+LRSF WQ
Sbjct: 1   MAPEENAGSELLLQSFKRRFLAARALRSFRWQ 32


>gi|24211015 hypothetical protein LOC55199 isoform 2 [Homo sapiens]
          Length = 131

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 26/32 (81%), Positives = 29/32 (90%)

Query: 416 MAPEENAGTELWLQGFERRFLAARSLRSFPWQ 447
           MAPEENAG+EL LQ F+RRFLAAR+LRSF WQ
Sbjct: 1   MAPEENAGSELLLQSFKRRFLAARALRSFRWQ 32


>gi|239754822 PREDICTED: hypothetical protein LOC653333 [Homo
           sapiens]
          Length = 329

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 25/32 (78%), Positives = 27/32 (84%)

Query: 416 MAPEENAGTELWLQGFERRFLAARSLRSFPWQ 447
           M PEENAGT+L LQ FE RFL AR+LRSFPWQ
Sbjct: 1   MTPEENAGTKLLLQSFESRFLVARTLRSFPWQ 32


>gi|223633935 hypothetical protein LOC254427 [Homo sapiens]
          Length = 435

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 74/283 (26%), Positives = 98/283 (34%), Gaps = 48/283 (16%)

Query: 216 CLLCSAERRNCESAYVSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASED 275
           C LCS       S+   P         +DL  PA  A   +  P   +  GPA  PA ++
Sbjct: 87  CCLCSPSLEESTSSPSEPED------VIDLVQPAPGAGEAEGLPEGTQAAGPA--PAGKE 138

Query: 276 HGLAPGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCP-----HARHCL 330
           H      +  PP    PE+         ++  PPLP    P    L  P     H R   
Sbjct: 139 HRKQDAETPPPPDPPAPET---------LLAPPPLPSTPDPPRRELRAPSPPVEHPRLLR 189

Query: 331 QDAT----------NLNASEAQLPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLLTVSPG 380
              T           +  +EA  P SP+    PG          P    PR+      PG
Sbjct: 190 SVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWR------TPAARGPRSG----DPG 239

Query: 381 PAPSLP--PRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEENAGTELWLQGFERRFLAA 438
           P PS P  P+    P  +    G  +  R+    A V   E  A     + G    F AA
Sbjct: 240 PGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAA 299

Query: 439 RSLRSFPWQVAGGASGE-ARGGRGSPG-ADGMGLGAETPGAPA 479
               +      GG+S E    GRG PG A+ +  G + P  PA
Sbjct: 300 GD--AGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPA 340


>gi|223941923 OTU domain containing 1 [Homo sapiens]
          Length = 481

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 77/304 (25%), Positives = 105/304 (34%), Gaps = 86/304 (28%)

Query: 247 GPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRLPESA--HRLAV---- 300
           GP + AP P +A    ++    PG A    G AP P +   Q   P +A  HR A     
Sbjct: 17  GPTAAAPAPPAAATPFKVSLQPPGAA----GAAPEPETGECQ---PAAAAEHREAAAVPA 69

Query: 301 --------CYDIVNAPPLPRLLSPSLGLLSC-----PHARHCLQDATN-LNASEAQLPGS 346
                   C+++V+    P   +      SC     PH     Q     L A    L G 
Sbjct: 70  AKMPAFSSCFEVVSGAAAPASAAAGPPGASCKPPLPPHYTSTAQITVRALGADRLLLHG- 128

Query: 347 PYPGPAPGTANLDSPQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRPGFLQVS 406
             P P PG A           +APR   L ++P PA  +PPR       L+      ++ 
Sbjct: 129 --PDPVPGAAG--------SAAAPRGRCLLLAPAPAAPVPPRRGSSAWLLE------ELL 172

Query: 407 RQRCGSAHVMAPEENAGTELWLQGFERRFLAARSLRSFPWQVAGGASGEARGGRGSPGAD 466
           R  C         E AG +   +G +R F  +   ++        A+ + RG        
Sbjct: 173 RPDC--------PEPAGLDATREGPDRNFRLSEHRQAL-------AAAKHRGP------- 210

Query: 467 GMGLGAETPGAPATCVPGLSPVRAARPGPRPWGLARVARTPSAPRAGGGSWGRLHRPGGQ 526
                A TPG+P              PGP PWG   +A     PR       R   PGG 
Sbjct: 211 -----AATPGSPD-------------PGPGPWGEEHLAE--RGPRGWERGGDRCDAPGGD 250

Query: 527 TRVR 530
              R
Sbjct: 251 AARR 254



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 47/167 (28%), Positives = 58/167 (34%), Gaps = 30/167 (17%)

Query: 372 THLLTVSPGPAPSLPPRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEENAGTELWLQGF 431
           TH    +PGP  + P       PP  + P   +VS Q  G+A   APE   G        
Sbjct: 9   THYPAGAPGPTAAAPA------PPAAATP--FKVSLQPPGAAGA-APEPETGECQPAAAA 59

Query: 432 ERRFLAARSLRSFP-----WQVAGGASGEARGGRGSPGAD-----------GMGLGAETP 475
           E R  AA      P     ++V  GA+  A    G PGA               +     
Sbjct: 60  EHREAAAVPAAKMPAFSSCFEVVSGAAAPASAAAGPPGASCKPPLPPHYTSTAQITVRAL 119

Query: 476 GAPATCVPGLSPV-----RAARPGPRPWGLARVARTPSAPRAGGGSW 517
           GA    + G  PV      AA P  R   LA     P  PR G  +W
Sbjct: 120 GADRLLLHGPDPVPGAAGSAAAPRGRCLLLAPAPAAPVPPRRGSSAW 166


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 49/167 (29%), Positives = 62/167 (37%), Gaps = 27/167 (16%)

Query: 235 PDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAP-GPASEDHGLAPGPSSNPPQLRLPE 293
           P P  P  L L  P    P+P ++PP   +  P+P  P +    L   P S PP      
Sbjct: 392 PPPQAPPALALP-PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP------ 444

Query: 294 SAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAP 353
                        +PP+    SP       P A    Q   +L A   Q+P SP   P  
Sbjct: 445 -------------SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491

Query: 354 GTANLDSPQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRP 400
             +    PQ  P  +AP   L      P P  PP  AL  PPLQ+ P
Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAK----PPPQAPP--ALATPPLQALP 532



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 86/322 (26%), Positives = 108/322 (33%), Gaps = 48/322 (14%)

Query: 232 SPRPDPTI--PGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPP-Q 288
           SP P P +  P +   + P S +  P S  P      P   P S        PS+ PP Q
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500

Query: 289 LRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPY 348
              P +A  L +      AP  P L +P L  L  P A    Q   + +AS   LP SP 
Sbjct: 501 APPPLAAPPLQLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSAS---LPMSPL 555

Query: 349 PGPAPGTANL---------DSPQDLPQQSAPRTHLLTVSPGP-----APSLPPRTALGPP 394
             P P    +          SP   P   APR      +PGP      P L    A GPP
Sbjct: 556 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---PPTPGPDTSVSGPRLTLALAPGPP 612

Query: 395 PLQSRPGFLQVSRQRC---GSAHVMAPEENAGTELWLQGFERRF----LAARSLRSFPWQ 447
           P  SR     +S        S+    PEE  G +   +G             +     W 
Sbjct: 613 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 672

Query: 448 VAGGASGEARGGRGSP----------GADGMGLGAETPG------APATCVPGLSPVRAA 491
                    RG  G+P           ADG+    ET G      AP    PG SP  + 
Sbjct: 673 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 732

Query: 492 RPGPRPWGLARVARTPSAPRAG 513
                  G    +R+P   R G
Sbjct: 733 GKAAAGAGAGASSRSPKQARLG 754



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 61/212 (28%), Positives = 81/212 (38%), Gaps = 26/212 (12%)

Query: 196 GAENPLGQCLSLNPLLILSTCLLCSAERRNCESAYVSPRPDPTIPGTLDLTGPASRAPNP 255
           G + P  + LS       S+    S+  R+  SA  +PR  P  P      G  +  P P
Sbjct: 233 GLQRPASRSLS-------SSATPLSSPARSGPSARGTPRA-PAHPSQPKPKGLQALRP-P 283

Query: 256 DSAPPKLRILGPAPGPASEDHGLAPGPSSN-----PPQLRLPESAHRLAVCYDIVN---- 306
              PP+ +   PA GP S      P PS+      PP L  P + H  ++   +      
Sbjct: 284 QVTPPR-KDAAPALGPLSSSPLATPSPSAALQSQAPPTL--PATPHSSSLTCQLATPLPL 340

Query: 307 APPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAPGTANLDSPQDLPQ 366
           APP P    PSL  L  P A    Q  T+L +   Q   S  P P         PQ  P 
Sbjct: 341 APPSPSA-PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 399

Query: 367 QSAPRTHLLTVSPGPAPSLPPRTALGPPPLQS 398
            + P    L   P P P+ PP + L  P  Q+
Sbjct: 400 LALPP---LQAPPSP-PASPPLSPLATPSPQA 427



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 73/308 (23%), Positives = 102/308 (33%), Gaps = 50/308 (16%)

Query: 222 ERRNCESAYVSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPG----PASEDHG 277
           +R   ++   +  P    PG L    P S  P P   P  LR+LG A      P +E  G
Sbjct: 4   KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63

Query: 278 LAPGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGL-LSCPHARHCLQDATNL 336
              G +       +PESA R         +   P    P+ G     P A++        
Sbjct: 64  GIGGAT-------IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT------- 109

Query: 337 NASEAQLPGSPYPGPAPGTAN-LDSPQDLPQQSAPRTHLLTVSPGPAPSLPPRTAL---- 391
                    SP P  +PG A+    P  L Q+    +   TV+ G A   P R+AL    
Sbjct: 110 ---------SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160

Query: 392 -----GPPPLQSRPGFLQVSRQRCGSAHVMAPEENAGTELWLQGFERRFLAARSLRSFPW 446
                GP P    P   + SR       +  P  +A      +G  +   +A    +   
Sbjct: 161 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220

Query: 447 QVAGGASGEARGGRGSPGADGMGLGAETPGAPATCVPGLSPVRAARPGPRPWGLARVART 506
             A      A GG   P +  +   A    +P            AR GP   G  R    
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSP------------ARSGPSARGTPRAPAH 268

Query: 507 PSAPRAGG 514
           PS P+  G
Sbjct: 269 PSQPKPKG 276



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 45/162 (27%), Positives = 63/162 (38%), Gaps = 17/162 (10%)

Query: 245 LTGPASRAPNPDSAPPKLRILGPA-PGPASEDHGLAPGPSSNPPQLRLPESAHRLAVCYD 303
           L  PASR+ +  + P    +  PA  GP++     AP   S P     P+    L     
Sbjct: 234 LQRPASRSLSSSATP----LSSPARSGPSARGTPRAPAHPSQPK----PKGLQALRP--- 282

Query: 304 IVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAPGTANLDSPQD 363
                P  +  +P+LG LS          A   + +   LP +P+      T  L +P  
Sbjct: 283 -PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL--TCQLATPLP 339

Query: 364 L--PQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRPGFL 403
           L  P  SAP +     SP   P     T+LG P LQ+   FL
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 381



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 38/129 (29%), Positives = 44/129 (34%), Gaps = 30/129 (23%)

Query: 233 PRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPG-----PSSNPP 287
           P P  T PG+ D          P+SA P    L P P P +     A G      S +P 
Sbjct: 690 PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPK 749

Query: 288 QLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSP 347
           Q RL E                LP      LG L     +H L     L A+E    GS 
Sbjct: 750 QARLGE----------------LP------LGALQASVVQHLLSRTLLLAAAEGAAGGS- 786

Query: 348 YPGPAPGTA 356
             G  PG A
Sbjct: 787 --GGGPGGA 793


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 52/173 (30%), Positives = 61/173 (35%), Gaps = 27/173 (15%)

Query: 232 SPRPDPTIPGTLDLTGPASRAPN---------PDSAPPKLRILGPAPGPASEDHGLAPGP 282
           +P   P  P    L  P+ +APN         P S PP   +  P   PAS        P
Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP----VSP 687

Query: 283 SSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQ 342
           S+ PP    P  A           APPL    SP       P A    Q    L A   Q
Sbjct: 688 SATPPSQAPPSLA-----------APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736

Query: 343 LPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPP 395
           +P SP   P    +    P+  P  +AP    L V P P  SLP      PPP
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPP---LQVPPSPPASLPMSPLAKPPP 786



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 51/181 (28%), Positives = 66/181 (36%), Gaps = 26/181 (14%)

Query: 218 LCSAERRNCESAYVSP--RPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAP-GPASE 274
           L S   +   S  +SP   P P  P  L L  P    P+P ++PP   +  P+P  P + 
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALP-PLQAPPSPPASPPLSPLATPSPQAPNAL 656

Query: 275 DHGLAPGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDAT 334
              L   P S PP                   +PP+    SP       P A    Q   
Sbjct: 657 AVHLLQAPFSPPP-------------------SPPVQAPFSPPASPPVSPSATPPSQAPP 697

Query: 335 NLNASEAQLPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPP 394
           +L A   Q+P SP   P    +    PQ  P  +AP    L V P P  S P   +  PP
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP---LQVPPSPPASPPMSPSATPP 754

Query: 395 P 395
           P
Sbjct: 755 P 755



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 73/308 (23%), Positives = 102/308 (33%), Gaps = 50/308 (16%)

Query: 222 ERRNCESAYVSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPG----PASEDHG 277
           +R   ++   +  P    PG L    P S  P P   P  LR+LG A      P +E  G
Sbjct: 4   KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63

Query: 278 LAPGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGL-LSCPHARHCLQDATNL 336
              G +       +PESA R         +   P    P+ G     P A++        
Sbjct: 64  GIGGAT-------IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT------- 109

Query: 337 NASEAQLPGSPYPGPAPGTAN-LDSPQDLPQQSAPRTHLLTVSPGPAPSLPPRTAL---- 391
                    SP P  +PG A+    P  L Q+    +   TV+ G A   P R+AL    
Sbjct: 110 ---------SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160

Query: 392 -----GPPPLQSRPGFLQVSRQRCGSAHVMAPEENAGTELWLQGFERRFLAARSLRSFPW 446
                GP P    P   + SR       +  P  +A      +G  +   +A    +   
Sbjct: 161 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220

Query: 447 QVAGGASGEARGGRGSPGADGMGLGAETPGAPATCVPGLSPVRAARPGPRPWGLARVART 506
             A      A GG   P +  +   A    +P            AR GP   G  R    
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSP------------ARSGPSARGTPRAPAH 268

Query: 507 PSAPRAGG 514
           PS P+  G
Sbjct: 269 PSQPKPKG 276



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 59/229 (25%), Positives = 84/229 (36%), Gaps = 11/229 (4%)

Query: 196 GAENPLGQCLSLNPLLILSTCLLCSAERRNCESAYVSPRPDPTIPGTLDLTGPASRAPNP 255
           G + P  + LS       S+    S+  R+  SA  +PR  P  P      G  +  P P
Sbjct: 233 GLQRPASRSLS-------SSATPLSSPARSGPSARGTPRA-PAHPSQPKPKGLQALRP-P 283

Query: 256 DSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLS 315
              PP+ +   PA GP S      P PS    +   P       +   +  +PPL   L 
Sbjct: 284 QVTPPR-KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP 342

Query: 316 PSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLL 375
            +    S P +   L        S+A    +  P  AP +     P  +P      +   
Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402

Query: 376 TVSPGPAPSLPPRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEENAGT 424
             SP    SL   T+LG P LQ+   FL +S  R   A + +P   A T
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMS-PRQTQASLTSPSRPAST 450



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 52/171 (30%), Positives = 62/171 (36%), Gaps = 33/171 (19%)

Query: 248 PASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAVCYDIVNA 307
           P+S A  P  APP L        P+     LA  P   PP L LP            + A
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP-----------LQA 632

Query: 308 PPLPRLLSPSLGLLSCPH-------ARHCLQDATNLNASE-AQLPGSPYPGPAPGTANLD 359
           PP P   SP L  L+ P        A H LQ   +   S   Q P SP P   P + +  
Sbjct: 633 PPSPPA-SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVSPSAT 690

Query: 360 SPQDLPQQ----------SAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRP 400
            P   P            S P +  ++ S  P P  PP   L  PPLQ  P
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--PLAAPPLQVPP 739



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 59/230 (25%), Positives = 86/230 (37%), Gaps = 26/230 (11%)

Query: 193 TINGAENPLGQCLSLNPLLILSTCLLCSAERR---------NCESAYVSP--RPDPTIPG 241
           +++ A +PL   L+++PL  LS+    S +             +S+   P  +  P    
Sbjct: 472 SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT 531

Query: 242 TLDLTGPASRAPNP---DSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRLPESAHRL 298
           T  L    S AP P    SAP     L   P PA       P P + PP    PE+   +
Sbjct: 532 TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP----PETPSSI 587

Query: 299 AV----CYDIVNAPPLPRLLSPSLGLLSCPHARH----CLQDATNLNASEAQLPGSPYPG 350
           A         + +PPL  L SP L  L+ P  +      L       +  A  P SP   
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647

Query: 351 PAPGTANLDSPQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRP 400
           P+P   N  +   L    +P       +P   P+ PP +    PP Q+ P
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 15/117 (12%)

Query: 282 PSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEA 341
           P+S PP       +  L     +  +PPL   LSP++  LS P   H LQ  ++L +   
Sbjct: 447 PASTPPD------SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500

Query: 342 QLPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQS 398
           Q P S    P   T +  +P   P    P   L T      P L    +L PPPLQ+
Sbjct: 501 QAPLSSLIMPPLETQSSLAP---PSLQTPPASLTT------PPLENLPSLAPPPLQT 548



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 66/251 (26%), Positives = 92/251 (36%), Gaps = 40/251 (15%)

Query: 232  SPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRL 291
            +P PD ++ G       A   P P S  P   + GP      +  G +   +S P +LR 
Sbjct: 860  TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP------DLAGHSSSATSTPEELRG 913

Query: 292  PESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYP-G 350
             +S            +PP      P   L +C  A      A  L    A  PG+P P  
Sbjct: 914  YDSGPEGGA----AASPP------PDAELAACHPAAWSRGPAPPLAFRGA--PGAPLPWP 961

Query: 351  PAPGTANLDSPQDLPQQSAPRTHLLTV--SPGPAPSLPPRTALGPPPLQSRPGFLQVSRQ 408
            PA G  + D              L T+  + GP  + P   AL P P     G    +  
Sbjct: 962  PATGPGSADG-------------LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 1008

Query: 409  RCGSAHVMAPEENAGTELWLQGFERRFLAARSLRSFPWQVAGGASGEARGGRGSPGADGM 468
              G A   +P++    EL L   +   +     R+     A GA+G + GG G  GA+G 
Sbjct: 1009 GAG-ASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPG--GAEG- 1064

Query: 469  GLGAETPGAPA 479
              G  T GA A
Sbjct: 1065 --GGVTGGARA 1073


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 49/167 (29%), Positives = 62/167 (37%), Gaps = 27/167 (16%)

Query: 235 PDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAP-GPASEDHGLAPGPSSNPPQLRLPE 293
           P P  P  L L  P    P+P ++PP   +  P+P  P +    L   P S PP      
Sbjct: 353 PPPQAPPALALP-PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP------ 405

Query: 294 SAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAP 353
                        +PP+    SP       P A    Q   +L A   Q+P SP   P  
Sbjct: 406 -------------SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 452

Query: 354 GTANLDSPQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRP 400
             +    PQ  P  +AP   L      P P  PP  AL  PPLQ+ P
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAK----PPPQAPP--ALATPPLQALP 493



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 86/322 (26%), Positives = 108/322 (33%), Gaps = 48/322 (14%)

Query: 232 SPRPDPTI--PGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPP-Q 288
           SP P P +  P +   + P S +  P S  P      P   P S        PS+ PP Q
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461

Query: 289 LRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPY 348
              P +A  L +      AP  P L +P L  L  P A    Q   + +AS   LP SP 
Sbjct: 462 APPPLAAPPLQLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSAS---LPMSPL 516

Query: 349 PGPAPGTANL---------DSPQDLPQQSAPRTHLLTVSPGP-----APSLPPRTALGPP 394
             P P    +          SP   P   APR      +PGP      P L    A GPP
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---PPTPGPDTSVSGPRLTLALAPGPP 573

Query: 395 PLQSRPGFLQVSRQRC---GSAHVMAPEENAGTELWLQGFERRF----LAARSLRSFPWQ 447
           P  SR     +S        S+    PEE  G +   +G             +     W 
Sbjct: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 633

Query: 448 VAGGASGEARGGRGSP----------GADGMGLGAETPG------APATCVPGLSPVRAA 491
                    RG  G+P           ADG+    ET G      AP    PG SP  + 
Sbjct: 634 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 693

Query: 492 RPGPRPWGLARVARTPSAPRAG 513
                  G    +R+P   R G
Sbjct: 694 GKAAAGAGAGASSRSPKQARLG 715



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 74/308 (24%), Positives = 102/308 (33%), Gaps = 59/308 (19%)

Query: 222 ERRNCESAYVSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPG----PASEDHG 277
           +R   ++   +  P    PG L    P S  P P   P  LR+LG A      P +E  G
Sbjct: 4   KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63

Query: 278 LAPGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGL-LSCPHARHCLQDATNL 336
              G +       +PESA R         A P      P+ G     P A++        
Sbjct: 64  GIGGAT-------IPESAPR---------AGPTRTSRPPASGRGERAPPAKNT------- 100

Query: 337 NASEAQLPGSPYPGPAPGTAN-LDSPQDLPQQSAPRTHLLTVSPGPAPSLPPRTAL---- 391
                    SP P  +PG A+    P  L Q+    +   TV+ G A   P R+AL    
Sbjct: 101 ---------SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 151

Query: 392 -----GPPPLQSRPGFLQVSRQRCGSAHVMAPEENAGTELWLQGFERRFLAARSLRSFPW 446
                GP P    P   + SR       +  P  +A      +G  +   +A    +   
Sbjct: 152 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 211

Query: 447 QVAGGASGEARGGRGSPGADGMGLGAETPGAPATCVPGLSPVRAARPGPRPWGLARVART 506
             A      A GG   P +  +   A    +P            AR GP   G  R    
Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSP------------ARSGPSARGTPRAPAH 259

Query: 507 PSAPRAGG 514
           PS P+  G
Sbjct: 260 PSQPKPKG 267



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 56/203 (27%), Positives = 71/203 (34%), Gaps = 38/203 (18%)

Query: 196 GAENPLGQCLSLNPLLILSTCLLCSAERRNCESAYVSPRPDPTIPGTLDLTGPASRAPNP 255
           G + P  + LS       S+    S+  R+  SA  +PR  P  P      G  +  P P
Sbjct: 224 GLQRPASRSLS-------SSATPLSSPARSGPSARGTPRA-PAHPSQPKPKGLQALRP-P 274

Query: 256 DSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLS 315
              PP+ +   PA GP S      P PS                       APP P    
Sbjct: 275 QVTPPR-KDAAPALGPLSSSPLATPSPS-----------------------APPSPSA-P 309

Query: 316 PSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLL 375
           PSL  L  P A    Q  T+L +   Q   S  P P         PQ  P  + P    L
Sbjct: 310 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP---L 366

Query: 376 TVSPGPAPSLPPRTALGPPPLQS 398
              P P P+ PP + L  P  Q+
Sbjct: 367 QAPPSP-PASPPLSPLATPSPQA 388



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 55/207 (26%), Positives = 73/207 (35%), Gaps = 50/207 (24%)

Query: 247 GPASRAPNPD--SAPPKLRILGPAPGP-----------ASEDHGLA-PGPSSNP-PQLRL 291
           G A+ AP     SA  +    GP PG            A  + GL  P PS+ P P    
Sbjct: 136 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 195

Query: 292 PESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPGP 351
           P  +   A  +      P  R    + G L  P +R     AT L++     P +     
Sbjct: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 255

Query: 352 APGTANLDSPQDL-----PQQSAPR------------THLLTVSPG--PAPSLPPR---- 388
           AP   +   P+ L     PQ + PR            + L T SP   P+PS PP     
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315

Query: 389 ------------TALGPPPLQSRPGFL 403
                       T+LG P LQ+   FL
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFL 342



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 38/129 (29%), Positives = 44/129 (34%), Gaps = 30/129 (23%)

Query: 233 PRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPG-----PSSNPP 287
           P P  T PG+ D          P+SA P    L P P P +     A G      S +P 
Sbjct: 651 PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPK 710

Query: 288 QLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSP 347
           Q RL E                LP      LG L     +H L     L A+E    GS 
Sbjct: 711 QARLGE----------------LP------LGALQASVVQHLLSRTLLLAAAEGAAGGS- 747

Query: 348 YPGPAPGTA 356
             G  PG A
Sbjct: 748 --GGGPGGA 754


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 58/205 (28%), Positives = 77/205 (37%), Gaps = 42/205 (20%)

Query: 240  PGTLDLTGPA-------SRAPNPDSAP--PKLRILGPAPGPASEDHGLAPGPSSNPPQLR 290
            P T+  +GPA         AP   +AP  P L   G +P  ++   GLA  PS +  Q  
Sbjct: 1462 PLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQ-- 1519

Query: 291  LPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPG 350
                 H L +     + P L   ++P+   +  P             AS    P    P 
Sbjct: 1520 --TPGHPLLLAPTSSHVPGLNSTVAPACSPVLVP-------------ASALASPFPSAPN 1564

Query: 351  PAPGTANLDSPQD---------LPQQSAPRTHLLTVSPGPAPSLPPRTALGPPPLQSRPG 401
            PAP  A+L +P           L   +AP+T +L  +P PAP L P   L P      PG
Sbjct: 1565 PAPAQASLLAPASSASQALATPLAPMAAPQTAIL--APSPAPPLAPLPVLAP-----SPG 1617

Query: 402  FLQVSRQRCGSAHVMAPEENAGTEL 426
               V         VMAP    GT L
Sbjct: 1618 AAPVLASSQTPVPVMAPSSTPGTSL 1642



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 46/175 (26%), Positives = 61/175 (34%), Gaps = 22/175 (12%)

Query: 219  CSAERRNCESAYVSPRPDP-TIPGTLDLTGPAS-RAPNPDSAPPKLRILG----PAPGPA 272
            CS  R         PRP P + P  +    P    AP P SAP  + IL     P+P P 
Sbjct: 2429 CSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPP 2488

Query: 273  SEDHGLAPGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQD 332
            S+    +  P+  PP    P  AH        +  P  P LL P                
Sbjct: 2489 SQIPPCS-SPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGP---------------P 2532

Query: 333  ATNLNASEAQLPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLLTVSPGPAPSLPP 387
            +  ++AS   LP    P        L SP+ L   S   +   ++S  P   L P
Sbjct: 2533 SVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLP 2587



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 49/181 (27%), Positives = 65/181 (35%), Gaps = 19/181 (10%)

Query: 228  SAYVSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPS---- 283
            SA   P P P +  +   T   +  P+P  +P   + L  AP  A    G +P  +    
Sbjct: 1644 SASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLG 1703

Query: 284  SNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQL 343
            +  PQ   P     L     +V  P     L+P   L              +L  +    
Sbjct: 1704 TGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPT--------QTLSLAPAPPLA 1755

Query: 344  PGSPYPGPAPG-TANLDSPQDLPQQSAPRT-HLLTVSPGPAPSLPPRT----ALGPPPLQ 397
            P SP  GPAP  T  L          AP +   LT+SP P P+L P      AL P   Q
Sbjct: 1756 PASPV-GPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQ 1814

Query: 398  S 398
            S
Sbjct: 1815 S 1815



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 43/167 (25%), Positives = 64/167 (38%), Gaps = 28/167 (16%)

Query: 231  VSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGP------------APGPASEDHGL 278
            V+P   P +     L  P   APNP  AP +  +L P            AP  A +   L
Sbjct: 1541 VAPACSPVLVPASALASPFPSAPNP--APAQASLLAPASSASQALATPLAPMAAPQTAIL 1598

Query: 279  APGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNA 338
            AP P+  PP   LP  A        + ++     +++PS    S P         T+L +
Sbjct: 1599 APSPA--PPLAPLPVLAPSPGAAPVLASSQTPVPVMAPS----STP--------GTSLAS 1644

Query: 339  SEAQLPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLLTVSPGPAPSL 385
            +      +P   P+     L +P   P  S   T  L ++P  AP+L
Sbjct: 1645 ASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTL 1691



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 45/188 (23%), Positives = 67/188 (35%), Gaps = 35/188 (18%)

Query: 225  NCESAYVSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSS 284
            N   A + P P    PG  +L+   +  P P   P  L +     GP        PGP  
Sbjct: 1013 NNPRAPLGPVPVRPPPGP-ELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVL 1071

Query: 285  NPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLP 344
             PP                  N+  LP++L   LG+LS                S    P
Sbjct: 1072 LPPLQ---------------PNSGSLPQVLPSPLGVLS------GTSRPPTPTLSLKPTP 1110

Query: 345  GSPY---PGPAPGTANLDSPQDLP----------QQSAPRTHLLTVSPGPAPSLPPRTAL 391
             +P    P P PG+++L  P  +P            ++  T   T +  PAP+  P+  +
Sbjct: 1111 PAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLI 1170

Query: 392  GPPPLQSR 399
              P +Q+R
Sbjct: 1171 LSPDMQAR 1178



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 57/214 (26%), Positives = 76/214 (35%), Gaps = 48/214 (22%)

Query: 228  SAYVSPRPDPT--IPGTLDLTGPASRA------PNPDSAPPKLRILGPAPGPASEDHG-L 278
            SA  SP P      P    L  PAS A      P    A P+  IL P+P P       L
Sbjct: 1553 SALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVL 1612

Query: 279  APGPSSNP----PQLRLPESAHRLAVCYDIVNAPPLPR---LLSPSLG--LLSCPHARHC 329
            AP P + P     Q  +P  A        + +A P+P    +L+PS    +L  P     
Sbjct: 1613 APSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPL 1672

Query: 330  LQDATNLNASEAQLPGSPYPGPAP------GTANLDSPQDLPQQSAPRT----------H 373
               A+    + A        G +P      GT N   P   P Q+   T           
Sbjct: 1673 PSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGP--FPTQTLSLTPASSLVPTPAQ 1730

Query: 374  LLTVSPGP------------APSLPPRTALGPPP 395
             L+++PGP            AP L P + +GP P
Sbjct: 1731 TLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAP 1764



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 62/251 (24%), Positives = 89/251 (35%), Gaps = 23/251 (9%)

Query: 267  PAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLL---SPSLGLLSC 323
            P P P S      P  +  P  L LP +A+++     +VN   + +++   +P  GL   
Sbjct: 1267 PGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPT--MVNNTGVVKIVVRQAPRDGLTPV 1324

Query: 324  PHARHCLQDATN-----LNASEAQLPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLLTVS 378
            P      +  ++     LN      PG   P P  GTA   +P   P    P   LL + 
Sbjct: 1325 PPLAPAPRPPSSGLPAVLNPRPTLTPGR-LPTPTLGTAR--APMPTPTLVRP---LLKLV 1378

Query: 379  PGPAPSLPPRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEENAGTELWLQGFERRFLAA 438
              P+P +        P   S P  L V     G A    P  N+     L       ++ 
Sbjct: 1379 HSPSPEVSASAPGAAPLTISSP--LHVPSSLPGPASSPMPIPNSSP---LASPVSSTVSV 1433

Query: 439  RSLRSFPWQVAGGASGEARGGRGSPGADGMGLGAETPGAPATCVPGLSPVRAARPGPRPW 498
                S P  V       A      P +  + + A  P    +  P L+PV  A PGP   
Sbjct: 1434 PLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPP-- 1491

Query: 499  GLARVARTPSA 509
             LA    +PSA
Sbjct: 1492 SLAPSGASPSA 1502


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23
           [Homo sapiens]
          Length = 1636

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 56/174 (32%), Positives = 70/174 (40%), Gaps = 42/174 (24%)

Query: 232 SPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLRL 291
           SP P  T PG   L+GP    P   S P +L I   APGP +    +APGP+  P     
Sbjct: 774 SPFPSSTGPGPHYLSGPLP--PGTYSGPTQL-IQPRAPGPHAMP--VAPGPALYPAPAYT 828

Query: 292 PESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYP-- 349
           PE                +PR  SP  G++S P+               A LP +P P  
Sbjct: 829 PELGL-------------VPRS-SPQHGVVSSPYV------GVGPAPPVAGLPSAPPPQF 868

Query: 350 -GPA------PGTANLDSPQ-DLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPP 395
            GP       P T  +DS Q  +P  +APR       P P P+ PP     PPP
Sbjct: 869 SGPELAMAVRPATTTVDSIQAPIPSHTAPR-------PNPTPAPPPPCFPVPPP 915



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 43/149 (28%), Positives = 52/149 (34%), Gaps = 16/149 (10%)

Query: 237  PTIPGTLDLTGPASRAPNPD---SAPPKLRIL---GPAPGPASEDHGLAPGPSSNPPQLR 290
            P  PG L    P   AP P      PP L      GPA  P     G  P PS  PPQ  
Sbjct: 986  PQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPP 1045

Query: 291  LPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYPG 350
             P  A+  A         P  R + P    L+        Q   + +   +  P SP PG
Sbjct: 1046 HPPLAYGPA---------PSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAP-SPGPG 1095

Query: 351  PAPGTANLDSPQDLPQQSAPRTHLLTVSP 379
            P P       P    ++ A    LL+ SP
Sbjct: 1096 PVPPRPPAAEPPPCLRRGAAAADLLSSSP 1124



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 49/170 (28%), Positives = 56/170 (32%), Gaps = 35/170 (20%)

Query: 253  PNPDSAPPKLRILGPAPG----PASEDHGLAPGPSSNPPQLRLPESAHRLAVCYDIVNAP 308
            P P   P   +  GP P     P    H   P      P L  P+S +  A    ++  P
Sbjct: 955  PQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPP----QAPGLLPPQSPYPYAPQPGVLGQP 1010

Query: 309  PLPRLLSPSLGLLSCPHARHCLQDATNLNASEAQLPGSPYP-------GPAPGTANLDSP 361
            P P       G    P   H         A     PG P P       GPAP T  +  P
Sbjct: 1011 PPPLHTQLYPGPAQDPLPAHS-------GALPFPSPGPPQPPHPPLAYGPAPSTRPM-GP 1062

Query: 362  QDLPQ---------QSAPRTHLL---TVSPGPAPSLPPRTALGPPPLQSR 399
            Q  P          QS P  HL+     SPGP P  P   A  PPP   R
Sbjct: 1063 QAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRR 1112



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 39/126 (30%), Positives = 51/126 (40%), Gaps = 18/126 (14%)

Query: 280 PGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHC-LQDATNLNA 338
           P P    P+  LP      AV  +  + P   R L P +  ++ P      L  AT L+ 
Sbjct: 716 PPPRPTAPKPLLPRREESEAV--EAGDPPEELRSLPPDM--VAGPRLPDTFLGSATPLHF 771

Query: 339 SEAQLPGSPYPGP-------APGTANLDSPQDLPQQSAPRTHLLTVSPG----PAPSLPP 387
             +  P S  PGP        PGT +   P  L Q  AP  H + V+PG    PAP+  P
Sbjct: 772 PPSPFPSSTGPGPHYLSGPLPPGTYS--GPTQLIQPRAPGPHAMPVAPGPALYPAPAYTP 829

Query: 388 RTALGP 393
              L P
Sbjct: 830 ELGLVP 835



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 19/61 (31%), Positives = 23/61 (37%)

Query: 231  VSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPPQLR 290
            V+  P P  P  L         P P S+PP L    P      E+  +   PSS PP   
Sbjct: 1517 VASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSS 1576

Query: 291  L 291
            L
Sbjct: 1577 L 1577


>gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6
           [Homo sapiens]
          Length = 440

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 21/152 (13%)

Query: 59  DFVTLCYREPDNVGHRFGPEAENRKLMIQQIGRT----------------IGVIITRDHG 102
           D   + +   D  GH +GP +  RK  ++ +                   + VII  DHG
Sbjct: 183 DLAAIYHERIDVEGHHYGPASPQRKDALKAVDTVLKYMTKWIQERGLQDRLNVIIFSDHG 242

Query: 103 VTTEKKRPNVNKIPLSNYIKFRDWVKFDIVGYGGFGMPLPKSGQEEALYQALKNAYPHLH 162
           +T       V  I L+ YI   D  +  +   G      P  G+   +Y  L +   H+ 
Sbjct: 243 MTDIFWMDKV--IELNKYISLNDLQQ--VKDRGPVVSLWPAPGKHSEIYNKL-STVEHMT 297

Query: 163 IYKKEEFPEHFHIAKHDRVLPIVMYANSGYTI 194
           +Y+KE  P  F+  K   V P+ + A+ G+ I
Sbjct: 298 VYEKEAIPSRFYYKKGKFVSPLTLVADEGWFI 329


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 82/319 (25%), Positives = 111/319 (34%), Gaps = 72/319 (22%)

Query: 228 SAYVSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASEDHGLAPGPSSNPP 287
           +A V+  P+P   G     GPA+ A      P      GP PGP     G  PG  + P 
Sbjct: 143 AAAVAAGPEPAPAGPAKPAGPAALAARAGPGP------GPGPGPGP---GPGPGKPAGPG 193

Query: 288 QLR-------LPESAHRLAVCYDIVNAPP-----LPRLLSPSLGLLSCPHARHCLQDATN 335
             +       L  S H  A    +VN  P     LP+  +P   + + P           
Sbjct: 194 AAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF---------- 243

Query: 336 LNASEAQLPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLLTVSPGPAPSLPPRTALGPPP 395
           + A+    P +P P  AP  A   +P   P    P    L   PG     P      PPP
Sbjct: 244 VGAAAPPAPAAPSPPAAPAPA---APAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP 300

Query: 396 LQSRPGFLQVSRQRCGSAHVM-APEENAGTELWLQGFERRFLAARSLRSFPWQVAGGASG 454
             ++ G         GSA    AP   AG    + G      AA +        A G   
Sbjct: 301 AAAQNG---------GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAA-------PAPGVKA 344

Query: 455 EA--RGGRGSPGADGMGLGAETPGAPAT------CVPGLSPVRAARPGP---RPWGLAR- 502
           E+  R  + +P A    L A  P + A        + G  P  AA P P    P GL + 
Sbjct: 345 ESPKRVVQAAPPA-AQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKG 403

Query: 503 --------VARTPSAPRAG 513
                   ++RTP+A  +G
Sbjct: 404 AAGAVTQSLSRTPTATTSG 422



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 76/325 (23%), Positives = 95/325 (29%), Gaps = 61/325 (18%)

Query: 235 PDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAP----------------GPASEDHGL 278
           P+P   G     G   + P P S    L   GPAP                 P      +
Sbjct: 87  PEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAV 146

Query: 279 APGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCPHARHCLQ-DATNLN 337
           A GP   P     P     LA        P       P  G  + P A   L   A  LN
Sbjct: 147 AAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLN 206

Query: 338 ASEAQLPG-----------SPYPGP-APGTANLDSPQDLPQQSAPRTHLLTVSPGPAPSL 385
           +  A  P             P P P APGT  + +P  +   + P     +    PAP+ 
Sbjct: 207 SHHAAAPAVSLVNNGPAALLPLPKPAAPGTV-IQTPPFVGAAAPPAPAAPSPPAAPAPAA 265

Query: 386 PPRTALGPPP----LQSRPGFLQVSRQRCGSAHVMAPEENAGTELWLQGFERRFLAARSL 441
           P      PPP    L   PG          +    A  +N G+                 
Sbjct: 266 PAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGS----------------- 308

Query: 442 RSFPWQVAGGASGEARGGRGSPGADGMGLGAETPGAPATCVPGLSP---VRAARPGPRPW 498
                  AG A   A    G  G  G         APA  V   SP   V+AA P  +  
Sbjct: 309 -------AGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTL 361

Query: 499 GLARVARTPSAPRAGGGSWGRLHRP 523
             +  A T ++   G    G L  P
Sbjct: 362 AASGPASTAASMVIGPTMQGALPSP 386


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.137    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,989,430
Number of Sequences: 37866
Number of extensions: 1951000
Number of successful extensions: 15675
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 958
Number of HSP's that attempted gapping in prelim test: 11319
Number of HSP's gapped (non-prelim): 4452
length of query: 542
length of database: 18,247,518
effective HSP length: 107
effective length of query: 435
effective length of database: 14,195,856
effective search space: 6175197360
effective search space used: 6175197360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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