BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|112382222 chloride channel Ka isoform 2 [Homo sapiens] (686 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|112382222 chloride channel Ka isoform 2 [Homo sapiens] 1374 0.0 gi|112382220 chloride channel Ka isoform 1 [Homo sapiens] 1370 0.0 gi|155969705 chloride channel Kb [Homo sapiens] 1260 0.0 gi|156104869 chloride channel 2 [Homo sapiens] 541 e-154 gi|119433677 chloride channel 1, skeletal muscle [Homo sapiens] 490 e-138 gi|153252026 chloride channel 4 [Homo sapiens] 194 2e-49 gi|189217923 chloride channel 5 isoform a [Homo sapiens] 186 5e-47 gi|189217921 chloride channel 5 isoform a [Homo sapiens] 186 5e-47 gi|4557473 chloride channel 5 isoform b [Homo sapiens] 186 5e-47 gi|55770838 chloride channel 3 isoform b [Homo sapiens] 179 6e-45 gi|55770840 chloride channel 3 isoform e [Homo sapiens] 176 8e-44 gi|167466160 chloride channel 7 isoform b [Homo sapiens] 146 5e-35 gi|14149607 chloride channel 7 isoform a [Homo sapiens] 146 5e-35 gi|4502873 chloride channel 6 isoform ClC-6a [Homo sapiens] 119 7e-27 gi|12025671 chloride channel 6 isoform ClC-6c [Homo sapiens] 73 1e-12 gi|12025673 chloride channel 6 isoform ClC-6d [Homo sapiens] 48 3e-05 gi|12025668 chloride channel 6 isoform ClC-6b [Homo sapiens] 48 3e-05 gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 31 3.3 gi|126352608 elastin isoform e precursor [Homo sapiens] 31 4.4 gi|126352446 elastin isoform d precursor [Homo sapiens] 31 4.4 gi|126352322 elastin isoform c precursor [Homo sapiens] 31 4.4 gi|126352700 elastin isoform b precursor [Homo sapiens] 31 4.4 gi|126352440 elastin isoform a precursor [Homo sapiens] 31 4.4 gi|156938237 ADP-ribosylation factor-like 17 isoform a [Homo sap... 31 4.4 gi|166063999 hypothetical protein LOC51326 isoform a [Homo sapiens] 31 4.4 gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 30 9.7 gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 30 9.7 gi|84508631 phosphatidylglycerophosphate synthase 1 [Homo sapiens] 30 9.7 gi|41349446 stromal interaction molecule 2 [Homo sapiens] 30 9.7 >gi|112382222 chloride channel Ka isoform 2 [Homo sapiens] Length = 686 Score = 1374 bits (3557), Expect = 0.0 Identities = 686/686 (100%), Positives = 686/686 (100%) Query: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM Sbjct: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60 Query: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG Sbjct: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120 Query: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL Sbjct: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180 Query: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF Sbjct: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240 Query: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL Sbjct: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300 Query: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS Sbjct: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360 Query: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP Sbjct: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420 Query: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH Sbjct: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480 Query: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI Sbjct: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540 Query: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV Sbjct: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600 Query: 601 QALQAEPPSRAPGHQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTSR 660 QALQAEPPSRAPGHQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTSR Sbjct: 601 QALQAEPPSRAPGHQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTSR 660 Query: 661 GRAVGCVSWVEMKKAISNLTNPPAPK 686 GRAVGCVSWVEMKKAISNLTNPPAPK Sbjct: 661 GRAVGCVSWVEMKKAISNLTNPPAPK 686 >gi|112382220 chloride channel Ka isoform 1 [Homo sapiens] Length = 687 Score = 1370 bits (3545), Expect = 0.0 Identities = 686/687 (99%), Positives = 686/687 (99%), Gaps = 1/687 (0%) Query: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM Sbjct: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60 Query: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG Sbjct: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120 Query: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL Sbjct: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180 Query: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF Sbjct: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240 Query: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL Sbjct: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300 Query: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS Sbjct: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360 Query: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP Sbjct: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420 Query: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH Sbjct: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480 Query: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI Sbjct: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540 Query: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV Sbjct: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600 Query: 601 QALQAEPPSRAPGH-QCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS 659 QALQAEPPSRAPGH QCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS Sbjct: 601 QALQAEPPSRAPGHQQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS 660 Query: 660 RGRAVGCVSWVEMKKAISNLTNPPAPK 686 RGRAVGCVSWVEMKKAISNLTNPPAPK Sbjct: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687 >gi|155969705 chloride channel Kb [Homo sapiens] Length = 687 Score = 1260 bits (3260), Expect = 0.0 Identities = 626/687 (91%), Positives = 651/687 (94%), Gaps = 1/687 (0%) Query: 1 MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDWYFLMTLGVLM 60 MEE VGLREG SG+PVTLQELWGPCP IRR I+GGLEWLKQK+FRLGEDWYFLMTLGVLM Sbjct: 1 MEEFVGLREGSSGNPVTLQELWGPCPRIRRGIRGGLEWLKQKLFRLGEDWYFLMTLGVLM 60 Query: 61 ALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120 ALVS AM+ A+ VVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG Sbjct: 61 ALVSCAMDLAVESVVRAHQWLYREIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGG 120 Query: 121 SGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYL 180 SGIPE+KTMLAGV+LEDYLDIKNFGAKVVGLSCTLA GSTLFLGKVGPFVHLSVM+AAYL Sbjct: 121 SGIPEVKTMLAGVVLEDYLDIKNFGAKVVGLSCTLACGSTLFLGKVGPFVHLSVMMAAYL 180 Query: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGF 240 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSV DYWRGF Sbjct: 181 GRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWDYWRGF 240 Query: 241 FAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYL 300 FAATCGAF+FRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGG+CG+L AYL Sbjct: 241 FAATCGAFMFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGLCGILGSAYL 300 Query: 301 FCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGVGHFLASRLSMKQHLDS 360 FCQR F FI+ NR+SSKLLATSKPVYSALATL+LASITYPP G FLASRLSMKQHLDS Sbjct: 301 FCQRIFFGFIRNNRFSSKLLATSKPVYSALATLVLASITYPPSAGRFLASRLSMKQHLDS 360 Query: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP Sbjct: 361 LFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIP 420 Query: 421 MPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH 480 MPAGYFMPIF+ GAAIGRL GE L+ FPEGIV GG+TNPIMPGGYALAGAAAFSGAVTH Sbjct: 421 MPAGYFMPIFVYGAAIGRLFGETLSFIFPEGIVAGGITNPIMPGGYALAGAAAFSGAVTH 480 Query: 481 TISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNI 540 TISTALLAFE+TGQIVHALPVLMAVLAANAIAQSCQPSFYDGT+IVKKLPYLPRILGRNI Sbjct: 481 TISTALLAFEVTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTVIVKKLPYLPRILGRNI 540 Query: 541 GSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600 GSH VRVEHFMNHSITTLAKD PLEEVVKVVTSTDV +YPLVESTESQILVGIV+RAQLV Sbjct: 541 GSHRVRVEHFMNHSITTLAKDMPLEEVVKVVTSTDVAKYPLVESTESQILVGIVRRAQLV 600 Query: 601 QALQAEPPSRAPGH-QCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTS 659 QAL+AEPPS APGH QCLQDILA GCPTEPVTL L ET+LH+A NLF+LLNL SLFVTS Sbjct: 601 QALKAEPPSWAPGHQQCLQDILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTS 660 Query: 660 RGRAVGCVSWVEMKKAISNLTNPPAPK 686 RGRAVGCVSWVEMKKAISNLTNPPAPK Sbjct: 661 RGRAVGCVSWVEMKKAISNLTNPPAPK 687 >gi|156104869 chloride channel 2 [Homo sapiens] Length = 898 Score = 541 bits (1395), Expect = e-154 Identities = 282/573 (49%), Positives = 386/573 (67%), Gaps = 9/573 (1%) Query: 43 VFRLGEDWYFLMTLGVLMALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVA 102 V R+GEDW FL+ LG+LMALVS+ M++AI ++A QW+ R + S LL+YL+W YPV Sbjct: 84 VSRVGEDWIFLVLLGLLMALVSWVMDYAIAACLQAQQWMSRGLNTSILLQYLAWVTYPVV 143 Query: 103 LVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLF 162 L++FS+GF+Q + P + GSGIPE+KT+L GV+L++YL +K F AKV+GL+C L GS + Sbjct: 144 LITFSAGFTQILAPQAVGSGIPEMKTILRGVVLKEYLTLKTFIAKVIGLTCAL--GSGMP 201 Query: 163 LGKVGPFVHLSVMIAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLF 222 LGK GPFVH++ M AA L + + G EN+S+ EML AA AVGV FAAP GVLF Sbjct: 202 LGKEGPFVHIASMCAALLSKFLSLFGGIYENESRNTEMLAAACAVGVGCCFAAPIGGVLF 261 Query: 223 SIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEI 282 SIEV S+ F+VR+YWRGFFAAT AFIFR+LAV+N ++ETIT+L+KT FR+D PFDL E+ Sbjct: 262 SIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQEL 321 Query: 283 FFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPP 342 F +G G +++ R + ++ + ++ L + ++ AL TLL++++T+PP Sbjct: 322 PAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMRKRLLFPALVTLLISTLTFPP 381 Query: 343 GVGHFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTL 402 G G F+A +LS K+ L +LFDN +W EEL+P W PR +F TL Sbjct: 382 GFGQFMAGQLSQKETLVTLFDNRTWVRQGL------VEELEPPSTSQAWNPPRANVFLTL 435 Query: 403 AFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIM 462 F++MKFWM LATTIP+P G FMP+F++GAA GRL+GE++A FP+GI T T I+ Sbjct: 436 VIFILMKFWMSALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIV 495 Query: 463 PGGYALAGAAAFSGAVTHTISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDG 522 PGGYA+ GAAA +GAVTHT+STA++ FELTGQI H LPV++AV+ ANA+AQS QPS YD Sbjct: 496 PGGYAVVGAAALAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDS 555 Query: 523 TIIVKKLPYLPRILGRNIGSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLV 582 I +KKLPYLP + + VRVE M + +A ++ + T LV Sbjct: 556 IIRIKKLPYLPELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALV 615 Query: 583 ESTESQILVGIVQRAQLVQALQAE-PPSRAPGH 614 ES ES IL+G ++R+Q+V L A+ P+R H Sbjct: 616 ESPESMILLGSIERSQVVALLGAQLSPARRRQH 648 Score = 45.1 bits (105), Expect = 2e-04 Identities = 20/52 (38%), Positives = 30/52 (57%) Query: 625 CPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAI 676 C +P L T+LH+ +F LL + +VTS GR +G V+ E++KAI Sbjct: 788 CKIDPAPFQLVERTSLHKTHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAI 839 >gi|119433677 chloride channel 1, skeletal muscle [Homo sapiens] Length = 988 Score = 490 bits (1262), Expect = e-138 Identities = 249/560 (44%), Positives = 370/560 (66%), Gaps = 10/560 (1%) Query: 45 RLGEDWYFLMTLGVLMALVSYAMNFAIGCVVRAHQWLYREIGDSHLLRYLSWTVYPVALV 104 +LGEDW FL+ LG+LMALVS++M++ ++A++W Y ++ S L++L W +P+ L+ Sbjct: 113 KLGEDWIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLI 172 Query: 105 SFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLG 164 FS+ F I+P + GSGIPE+KT+L GV+L++YL +K F AKVV L+ L GS + +G Sbjct: 173 LFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGL--GSGIPVG 230 Query: 165 KVGPFVHLSVMIAAYLGRVRTTTIGEPENKSKQNEMLVAAAAVGVATVFAAPFSGVLFSI 224 K GPFVH++ + AA L + + G E +++L AVGV F P GVLFSI Sbjct: 231 KEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSI 290 Query: 225 EVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFF 284 EV S++F+VR+YWRGFFAAT AF+FR+LAV+N + TIT+L++T+FR+D PFDL E+ Sbjct: 291 EVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPA 350 Query: 285 FVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSALATLLLASITYPPGV 344 F A+G CG+L +++ R + ++ ++ S+ LA + +Y + T ++AS T+PPG+ Sbjct: 351 FAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGM 410 Query: 345 GHFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAF 404 G F+A L ++ + +LFDN++W + PE L +W HPR + + Sbjct: 411 GQFMAGELMPREAISTLFDNNTWVKHAGD-----PESLGQSAVW---IHPRVNVVIIIFL 462 Query: 405 FLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPG 464 F VMKFWM I+ATT+P+P G FMP+F+LGAA GRL+GE +A+ FP+GI+ + I+PG Sbjct: 463 FFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPG 522 Query: 465 GYALAGAAAFSGAVTHTISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTI 524 GYA+ GAAA +GAV+HT+STA++ FELTGQI H LP+++AV+ AN +AQS QPS YD I Sbjct: 523 GYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSII 582 Query: 525 IVKKLPYLPRILGRNIGSHHVRVEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLVES 584 VKKLPYLP + + + + VE M + ++ E+ ++ +T V PLV+S Sbjct: 583 QVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDS 642 Query: 585 TESQILVGIVQRAQLVQALQ 604 +S IL+G V+R++L LQ Sbjct: 643 KDSMILLGSVERSELQALLQ 662 Score = 42.7 bits (99), Expect = 0.001 Identities = 26/82 (31%), Positives = 37/82 (45%) Query: 599 LVQALQAEPPSRAPGHQCLQDILARGCPTEPVTLTLFSETTLHQAQNLFKLLNLQSLFVT 658 LV + E Q Q + C + L +TTLH+ LF LL L +VT Sbjct: 793 LVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVT 852 Query: 659 SRGRAVGCVSWVEMKKAISNLT 680 S G+ G ++ E++KAI T Sbjct: 853 SMGKLRGVLALEELQKAIEGHT 874 >gi|153252026 chloride channel 4 [Homo sapiens] Length = 760 Score = 194 bits (494), Expect = 2e-49 Identities = 170/638 (26%), Positives = 289/638 (45%), Gaps = 70/638 (10%) Query: 84 EIGDSHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKN 143 E +++L YL + ++ + + + P + GSGIPE+KT+L+G I+ YL Sbjct: 144 EGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWT 203 Query: 144 FGAKVVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGEPENKSKQNEMLVA 203 K V L +++G L LGK GP VH++ + + + +N+ K+ E+L A Sbjct: 204 LLIKTVTLVLVVSSG--LSLGKEGPLVHVACCCGNFFSSLFSKY---SKNEGKRREVLSA 258 Query: 204 AAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETI 263 AAA GV+ F AP GVLFS+E +S +F ++ WR FFAA AF R + F + + Sbjct: 259 AAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR--- 315 Query: 264 TSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATS 323 L P+ + E+F F+ LG G+ ++ C + KT R Sbjct: 316 --LVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIRCNIAWCRRRKTTRLG------K 367 Query: 324 KPVYSAL-ATLLLASITYPPGVGHFLASRLSMKQHLDSLFDN----HSWALMTQNSSPPW 378 PV + T + A I YP +R S + + LF++ S L + P Sbjct: 368 YPVLEVIVVTAITAIIAYPNPY-----TRQSTSELISELFNDCGALESSQLCDYINDPNM 422 Query: 379 PEELD-----PQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFILG 433 +D P + +T LA L+ K + I + +P+G F+P +G Sbjct: 423 TRPVDDIPDRPAGV------GVYTAMWQLALALIFKIVVTIFTFGMKIPSGLFIPSMAVG 476 Query: 434 AAIGRLLG---EALAVAFPEGIVTGGVTNP----IMPGGYALAGAAAFSGAVTH-TISTA 485 A GR++G E LA + I+ P + PG YA+ GAAA G VT T+S Sbjct: 477 AIAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLV 536 Query: 486 LLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYL---PRILGRNIG 541 ++ FELTG + + +P++ A + + +A + + Y+ I + P+L R + Sbjct: 537 VIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLA 596 Query: 542 SHHVRVEHFMNHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQILVGIVQRAQLV 600 + +R ++ L +D+ +E+V ++ TD +P+V S +S+ L+G QR +L+ Sbjct: 597 TDVMRPRR-GEPPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSRDSERLIGFAQRRELI 655 Query: 601 QALQ-----------------AEPPSRAPGHQCLQDILARGCPTEPVTLTLFSETTLHQA 643 A++ E P P + L R P T+T T + Sbjct: 656 LAIKNARQRQEGIVSNSIMYFTEEPPELPANSPHPLKLRRILNLSPFTVT--DHTPMETV 713 Query: 644 QNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN 681 ++F+ L L+ VT GR +G ++ ++ + ++ + N Sbjct: 714 VDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMAN 751 >gi|189217923 chloride channel 5 isoform a [Homo sapiens] Length = 816 Score = 186 bits (473), Expect = 5e-47 Identities = 179/652 (27%), Positives = 293/652 (44%), Gaps = 107/652 (16%) Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAK 147 ++++ Y + ++ + + + P + GSGIPE+KT+L+G I+ YL K Sbjct: 205 AYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIK 264 Query: 148 VVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGE-PENKSKQNEMLVAAAA 206 + L LA S L LGK GP VH +A G + + +N++K+ E+L AAAA Sbjct: 265 TITL--VLAVSSGLSLGKEGPLVH----VACCCGNILCHCFNKYRKNEAKRREVLSAAAA 318 Query: 207 VGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSL 266 GV+ F AP GVLFS+E +S +F ++ WR FFAA AF R + F + + L Sbjct: 319 AGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR---LVL 375 Query: 267 YKTSFRVDVPFDLPEIFFFVAL---GGICGVLSCAYLFCQRTFLSFIKTN-RYSSKLLAT 322 + F P+ L E+ F+ L GG+ G L FI+TN + K T Sbjct: 376 FYVEFH--TPWHLFELVPFILLGIFGGLWGAL-------------FIRTNIAWCRKRKTT 420 Query: 323 SKPVYSALATLLLASIT----YPPGVGHFLASRLSMKQHLDSLFDN-------------H 365 Y + L++ +IT +P +R+S + + LF++ + Sbjct: 421 QLGKYPVIEVLVVTAITAILAFPNEY-----TRMSTSELISELFNDCGLLDSSKLCDYEN 475 Query: 366 SWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGY 425 + P P + W+ LA L++K + I + +P+G Sbjct: 476 RFNTSKGGELPDRPAGVGVYSAMWQ-----------LALTLILKIVITIFTFGMKIPSGL 524 Query: 426 FMPIFILGAAIGRLLG---EALAVAFPEGIVTGGVTNP----IMPGGYALAGAAAFSGAV 478 F+P +GA GRLLG E LA E V + I PG YA+ GAAA G V Sbjct: 525 FIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGV 584 Query: 479 TH-TISTALLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYLPRIL 536 T T+S ++ FELTG + + +P++ A + + +A + + YD I + P+L Sbjct: 585 TRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLE--- 641 Query: 537 GRNIGSHHVRVEHFM-----NHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQIL 590 + +H M + +T L +D+ +E+V +++ T + +P+V S ESQ L Sbjct: 642 AKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRL 701 Query: 591 VGIVQRAQLVQALQ--------------------AEP-PSRAPGHQCLQDILARGCPTEP 629 VG V R L+ +++ + P P P L++IL P Sbjct: 702 VGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNIL----DLSP 757 Query: 630 VTLTLFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN 681 T+T T + ++F+ L L+ VT GR +G ++ ++ K I+ + N Sbjct: 758 FTVT--DLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMAN 807 >gi|189217921 chloride channel 5 isoform a [Homo sapiens] Length = 816 Score = 186 bits (473), Expect = 5e-47 Identities = 179/652 (27%), Positives = 293/652 (44%), Gaps = 107/652 (16%) Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAK 147 ++++ Y + ++ + + + P + GSGIPE+KT+L+G I+ YL K Sbjct: 205 AYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIK 264 Query: 148 VVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGE-PENKSKQNEMLVAAAA 206 + L LA S L LGK GP VH +A G + + +N++K+ E+L AAAA Sbjct: 265 TITL--VLAVSSGLSLGKEGPLVH----VACCCGNILCHCFNKYRKNEAKRREVLSAAAA 318 Query: 207 VGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSL 266 GV+ F AP GVLFS+E +S +F ++ WR FFAA AF R + F + + L Sbjct: 319 AGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR---LVL 375 Query: 267 YKTSFRVDVPFDLPEIFFFVAL---GGICGVLSCAYLFCQRTFLSFIKTN-RYSSKLLAT 322 + F P+ L E+ F+ L GG+ G L FI+TN + K T Sbjct: 376 FYVEFH--TPWHLFELVPFILLGIFGGLWGAL-------------FIRTNIAWCRKRKTT 420 Query: 323 SKPVYSALATLLLASIT----YPPGVGHFLASRLSMKQHLDSLFDN-------------H 365 Y + L++ +IT +P +R+S + + LF++ + Sbjct: 421 QLGKYPVIEVLVVTAITAILAFPNEY-----TRMSTSELISELFNDCGLLDSSKLCDYEN 475 Query: 366 SWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGY 425 + P P + W+ LA L++K + I + +P+G Sbjct: 476 RFNTSKGGELPDRPAGVGVYSAMWQ-----------LALTLILKIVITIFTFGMKIPSGL 524 Query: 426 FMPIFILGAAIGRLLG---EALAVAFPEGIVTGGVTNP----IMPGGYALAGAAAFSGAV 478 F+P +GA GRLLG E LA E V + I PG YA+ GAAA G V Sbjct: 525 FIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGV 584 Query: 479 TH-TISTALLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYLPRIL 536 T T+S ++ FELTG + + +P++ A + + +A + + YD I + P+L Sbjct: 585 TRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLE--- 641 Query: 537 GRNIGSHHVRVEHFM-----NHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQIL 590 + +H M + +T L +D+ +E+V +++ T + +P+V S ESQ L Sbjct: 642 AKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRL 701 Query: 591 VGIVQRAQLVQALQ--------------------AEP-PSRAPGHQCLQDILARGCPTEP 629 VG V R L+ +++ + P P P L++IL P Sbjct: 702 VGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNIL----DLSP 757 Query: 630 VTLTLFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN 681 T+T T + ++F+ L L+ VT GR +G ++ ++ K I+ + N Sbjct: 758 FTVT--DLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMAN 807 >gi|4557473 chloride channel 5 isoform b [Homo sapiens] Length = 746 Score = 186 bits (473), Expect = 5e-47 Identities = 179/652 (27%), Positives = 293/652 (44%), Gaps = 107/652 (16%) Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAK 147 ++++ Y + ++ + + + P + GSGIPE+KT+L+G I+ YL K Sbjct: 135 AYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIK 194 Query: 148 VVGLSCTLATGSTLFLGKVGPFVHLSVMIAAYLGRVRTTTIGE-PENKSKQNEMLVAAAA 206 + L LA S L LGK GP VH +A G + + +N++K+ E+L AAAA Sbjct: 195 TITL--VLAVSSGLSLGKEGPLVH----VACCCGNILCHCFNKYRKNEAKRREVLSAAAA 248 Query: 207 VGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETITSL 266 GV+ F AP GVLFS+E +S +F ++ WR FFAA AF R + F + + L Sbjct: 249 AGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSR---LVL 305 Query: 267 YKTSFRVDVPFDLPEIFFFVAL---GGICGVLSCAYLFCQRTFLSFIKTN-RYSSKLLAT 322 + F P+ L E+ F+ L GG+ G L FI+TN + K T Sbjct: 306 FYVEFH--TPWHLFELVPFILLGIFGGLWGAL-------------FIRTNIAWCRKRKTT 350 Query: 323 SKPVYSALATLLLASIT----YPPGVGHFLASRLSMKQHLDSLFDN-------------H 365 Y + L++ +IT +P +R+S + + LF++ + Sbjct: 351 QLGKYPVIEVLVVTAITAILAFPNEY-----TRMSTSELISELFNDCGLLDSSKLCDYEN 405 Query: 366 SWALMTQNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGY 425 + P P + W+ LA L++K + I + +P+G Sbjct: 406 RFNTSKGGELPDRPAGVGVYSAMWQ-----------LALTLILKIVITIFTFGMKIPSGL 454 Query: 426 FMPIFILGAAIGRLLG---EALAVAFPEGIVTGGVTNP----IMPGGYALAGAAAFSGAV 478 F+P +GA GRLLG E LA E V + I PG YA+ GAAA G V Sbjct: 455 FIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGV 514 Query: 479 TH-TISTALLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYLPRIL 536 T T+S ++ FELTG + + +P++ A + + +A + + YD I + P+L Sbjct: 515 TRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLE--- 571 Query: 537 GRNIGSHHVRVEHFM-----NHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQIL 590 + +H M + +T L +D+ +E+V +++ T + +P+V S ESQ L Sbjct: 572 AKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRL 631 Query: 591 VGIVQRAQLVQALQ--------------------AEP-PSRAPGHQCLQDILARGCPTEP 629 VG V R L+ +++ + P P P L++IL P Sbjct: 632 VGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNIL----DLSP 687 Query: 630 VTLTLFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN 681 T+T T + ++F+ L L+ VT GR +G ++ ++ K I+ + N Sbjct: 688 FTVT--DLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMAN 737 >gi|55770838 chloride channel 3 isoform b [Homo sapiens] Length = 818 Score = 179 bits (455), Expect = 6e-45 Identities = 168/648 (25%), Positives = 283/648 (43%), Gaps = 98/648 (15%) Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAK 147 S+++ Y+ + + ++ + + P + GSGIPE+KT+L+G I+ YL K Sbjct: 206 SYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIK 265 Query: 148 VVGLSCTLATGSTLFLGKVGPFVHLSVM---IAAYLGRVRTTTIGEPENKSKQNEMLVAA 204 + L LA S L LGK GP VH++ I +YL +T N++K+ E+L AA Sbjct: 266 TITL--VLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYST------NEAKKREVLSAA 317 Query: 205 AAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETIT 264 +A GV+ F AP GVLFS+E +S +F ++ WR FFAA AF+ R + F + + Sbjct: 318 SAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSR---- 373 Query: 265 SLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSK 324 L P+ L E+F F+ LG G+ ++ + K+ ++ Sbjct: 374 -LVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGK------- 425 Query: 325 PVYSALATLLLASIT----YPPGVGHFLASRLSMKQHLD-------SLFD--NHSWALMT 371 Y L +++A+IT +P S L + D SL D N A Sbjct: 426 --YPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESSSLCDYRNDMNASKI 483 Query: 372 QNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFI 431 + P P + W+ L L+ K M + I +P+G F+P Sbjct: 484 VDDIPDRPAGIGVYSAIWQ-----------LCLALIFKIIMTVFTFGIKVPSGLFIPSMA 532 Query: 432 LGAAIGRLLGEALA---------VAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH-T 481 +GA GR++G A+ F E G + I PG YA+ GAAA G VT T Sbjct: 533 IGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVG--ADCITPGLYAMVGAAACLGGVTRMT 590 Query: 482 ISTALLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYLPRILGRNI 540 +S ++ FELTG + + +P++ AV+ + + + + Y+ I + P+L + Sbjct: 591 VSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLD---AKEE 647 Query: 541 GSHHVRVEHFM-----NHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQILVGIV 594 +H M + + L +D ++++ ++ T +P++ S ESQ LVG Sbjct: 648 FTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDIENMINETSYNGFPVIMSKESQRLVGFA 707 Query: 595 QRAQLVQALQA---------------------EPPSRAPGHQCLQDILARGCPTEPVTLT 633 R L A+++ P+ +P L+ IL P T+T Sbjct: 708 LRRDLTIAIESARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSIL----DMSPFTVT 763 Query: 634 LFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVSWVEMKKAISNLTN 681 T + ++F+ L L+ VT GR +G ++ ++ + ++ N Sbjct: 764 --DHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMAQTAN 809 >gi|55770840 chloride channel 3 isoform e [Homo sapiens] Length = 866 Score = 176 bits (445), Expect = 8e-44 Identities = 166/635 (26%), Positives = 276/635 (43%), Gaps = 98/635 (15%) Query: 88 SHLLRYLSWTVYPVALVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAK 147 S+++ Y+ + + ++ + + P + GSGIPE+KT+L+G I+ YL K Sbjct: 206 SYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIK 265 Query: 148 VVGLSCTLATGSTLFLGKVGPFVHLSVM---IAAYLGRVRTTTIGEPENKSKQNEMLVAA 204 + L LA S L LGK GP VH++ I +YL +T N++K+ E+L AA Sbjct: 266 TITL--VLAVASGLSLGKEGPLVHVACCCGNIFSYLFPKYST------NEAKKREVLSAA 317 Query: 205 AAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFRLLAVFNSEQETIT 264 +A GV+ F AP GVLFS+E +S +F ++ WR FFAA AF+ R + F + + Sbjct: 318 SAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSR---- 373 Query: 265 SLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSK 324 L P+ L E+F F+ LG G+ ++ + K+ ++ Sbjct: 374 -LVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGK------- 425 Query: 325 PVYSALATLLLASIT----YPPGVGHFLASRLSMKQHLD-------SLFD--NHSWALMT 371 Y L +++A+IT +P S L + D SL D N A Sbjct: 426 --YPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESSSLCDYRNDMNASKI 483 Query: 372 QNSSPPWPEELDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFI 431 + P P + W+ L L+ K M + I +P+G F+P Sbjct: 484 VDDIPDRPAGIGVYSAIWQ-----------LCLALIFKIIMTVFTFGIKVPSGLFIPSMA 532 Query: 432 LGAAIGRLLGEALA---------VAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH-T 481 +GA GR++G A+ F E G + I PG YA+ GAAA G VT T Sbjct: 533 IGAIAGRIVGIAVEQLAYYHHDWFIFKEWCEVG--ADCITPGLYAMVGAAACLGGVTRMT 590 Query: 482 ISTALLAFELTGQIVHALPVLMAVLAANAIAQSC-QPSFYDGTIIVKKLPYLPRILGRNI 540 +S ++ FELTG + + +P++ AV+ + + + + Y+ I + P+L + Sbjct: 591 VSLVVIVFELTGGLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLD---AKEE 647 Query: 541 GSHHVRVEHFM-----NHSITTLAKDT-PLEEVVKVVTSTDVTEYPLVESTESQILVGIV 594 +H M + + L +D ++++ ++ T +P++ S ESQ LVG Sbjct: 648 FTHTTLAADVMRPRRNDPPLAVLTQDNMTVDDIENMINETSYNGFPVIMSKESQRLVGFA 707 Query: 595 QRAQLVQALQA---------------------EPPSRAPGHQCLQDILARGCPTEPVTLT 633 R L A+++ P+ +P L+ IL P T+T Sbjct: 708 LRRDLTIAIESARKKQEGIVGSSRVCFAQHTPSLPAESPRPLKLRSIL----DMSPFTVT 763 Query: 634 LFSETTLHQAQNLFKLLNLQSLFVTSRGRAVGCVS 668 T + ++F+ L L+ VT G +G ++ Sbjct: 764 --DHTPMEIVVDIFRKLGLRQCLVTHNGIVLGIIT 796 >gi|167466160 chloride channel 7 isoform b [Homo sapiens] Length = 781 Score = 146 bits (369), Expect = 5e-35 Identities = 148/589 (25%), Positives = 260/589 (44%), Gaps = 60/589 (10%) Query: 50 WYFLMTLGVLMALVSYAMNFAIGC-------VVRAHQWLYREIGDSHLLRYLSWTVYPVA 102 W +G+L LV+ ++ + V++ + + E G L W A Sbjct: 103 WVICALIGILTGLVACFIDIVVENLAGLKYRVIKGNIDKFTEKGGLSF-SLLLWATLNAA 161 Query: 103 LVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLF 162 V S I P + GSGIP++K L GV + + +K KV G+ ++ G L Sbjct: 162 FVLVGSVIVAFIEPVAAGSGIPQIKCFLNGVKIPHVVRLKTLVIKVSGVILSVVGG--LA 219 Query: 163 LGKVGPFVHLSVMIAAYLGRVRTTTIGEP-------ENKSKQNEMLVAAAAVGVATVFAA 215 +GK GP +H +IAA + + R+T++ +++ + + A AA GV+ F A Sbjct: 220 VGKEGPMIHSGSVIAAGISQGRSTSLKRDFKIFEYFRRDTEKRDFVSAGAAAGVSAAFGA 279 Query: 216 PFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFR-LLAVFNSEQETITSLYKTSF-RV 273 P GVLFS+E +S ++ WR FFA+ F +L++++ ++S +F R Sbjct: 280 PVGGVLFSLEEGASFWNQFLTWRIFFASMISTFTLNFVLSIYHGNMWDLSSPGLINFGRF 339 Query: 274 D---VPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSAL 330 D + + + EI F+A+G + GVL + F ++ +P + Sbjct: 340 DSEKMAYTIHEIPVFIAMGVVGGVLGAVFNALNYWLTMF--------RIRYIHRPCLQVI 391 Query: 331 ATLLLASITYPPGVGHFLASR-------LSMKQHLDSLF--DNHSWALMTQNSSPPWPEE 381 +L+A++T +SR SM L LF D ++ + P Sbjct: 392 EAVLVAAVTATVAFVLIYSSRDCQPLQGGSMSYPL-QLFCADGEYNSMAAAFFNTPEKSV 450 Query: 382 LDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLG 441 + H Y+P TL F ++ F++ + + AG F+P ++GAA GRL G Sbjct: 451 VSLFHDPPGSYNPL-----TLGLFTLVYFFLACWTYGLTVSAGVFIPSLLIGAAWGRLFG 505 Query: 442 EALAVAFPEGIVTGGVTNPIMPGGYALAGAAA-FSGAVTHTISTALLAFELTGQIVHALP 500 +L+ I PG YAL GAAA G V T+S ++ E T + + P Sbjct: 506 ISLSYLTGAAIWAD-------PGKYALMGAAAQLGGIVRMTLSLTVIMMEATSNVTYGFP 558 Query: 501 VLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNIGSHHVRVEHFMNHSITTLAK 560 +++ ++ A + YD I ++ +P+L + SH + M+ +T L + Sbjct: 559 IMLVLMTAKIVGDVFIEGLYDMHIQLQSVPFLH--WEAPVTSHSLTAREVMSTPVTCLRR 616 Query: 561 DTPLEEVVKVV--TSTDVTEYPLVE---STESQILVGIVQRAQLVQALQ 604 + +V V+ T+++ +P+VE T+ L G++ R+QL+ L+ Sbjct: 617 REKVGVIVDVLSDTASNHNGFPVVEHADDTQPARLQGLILRSQLIVLLK 665 >gi|14149607 chloride channel 7 isoform a [Homo sapiens] Length = 805 Score = 146 bits (369), Expect = 5e-35 Identities = 148/589 (25%), Positives = 260/589 (44%), Gaps = 60/589 (10%) Query: 50 WYFLMTLGVLMALVSYAMNFAIGC-------VVRAHQWLYREIGDSHLLRYLSWTVYPVA 102 W +G+L LV+ ++ + V++ + + E G L W A Sbjct: 127 WVICALIGILTGLVACFIDIVVENLAGLKYRVIKGNIDKFTEKGGLSF-SLLLWATLNAA 185 Query: 103 LVSFSSGFSQSITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLF 162 V S I P + GSGIP++K L GV + + +K KV G+ ++ G L Sbjct: 186 FVLVGSVIVAFIEPVAAGSGIPQIKCFLNGVKIPHVVRLKTLVIKVSGVILSVVGG--LA 243 Query: 163 LGKVGPFVHLSVMIAAYLGRVRTTTIGEP-------ENKSKQNEMLVAAAAVGVATVFAA 215 +GK GP +H +IAA + + R+T++ +++ + + A AA GV+ F A Sbjct: 244 VGKEGPMIHSGSVIAAGISQGRSTSLKRDFKIFEYFRRDTEKRDFVSAGAAAGVSAAFGA 303 Query: 216 PFSGVLFSIEVMSSHFSVRDYWRGFFAATCGAFIFR-LLAVFNSEQETITSLYKTSF-RV 273 P GVLFS+E +S ++ WR FFA+ F +L++++ ++S +F R Sbjct: 304 PVGGVLFSLEEGASFWNQFLTWRIFFASMISTFTLNFVLSIYHGNMWDLSSPGLINFGRF 363 Query: 274 D---VPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSAL 330 D + + + EI F+A+G + GVL + F ++ +P + Sbjct: 364 DSEKMAYTIHEIPVFIAMGVVGGVLGAVFNALNYWLTMF--------RIRYIHRPCLQVI 415 Query: 331 ATLLLASITYPPGVGHFLASR-------LSMKQHLDSLF--DNHSWALMTQNSSPPWPEE 381 +L+A++T +SR SM L LF D ++ + P Sbjct: 416 EAVLVAAVTATVAFVLIYSSRDCQPLQGGSMSYPL-QLFCADGEYNSMAAAFFNTPEKSV 474 Query: 382 LDPQHLWWEWYHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFILGAAIGRLLG 441 + H Y+P TL F ++ F++ + + AG F+P ++GAA GRL G Sbjct: 475 VSLFHDPPGSYNPL-----TLGLFTLVYFFLACWTYGLTVSAGVFIPSLLIGAAWGRLFG 529 Query: 442 EALAVAFPEGIVTGGVTNPIMPGGYALAGAAA-FSGAVTHTISTALLAFELTGQIVHALP 500 +L+ I PG YAL GAAA G V T+S ++ E T + + P Sbjct: 530 ISLSYLTGAAIWAD-------PGKYALMGAAAQLGGIVRMTLSLTVIMMEATSNVTYGFP 582 Query: 501 VLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNIGSHHVRVEHFMNHSITTLAK 560 +++ ++ A + YD I ++ +P+L + SH + M+ +T L + Sbjct: 583 IMLVLMTAKIVGDVFIEGLYDMHIQLQSVPFLH--WEAPVTSHSLTAREVMSTPVTCLRR 640 Query: 561 DTPLEEVVKVV--TSTDVTEYPLVE---STESQILVGIVQRAQLVQALQ 604 + +V V+ T+++ +P+VE T+ L G++ R+QL+ L+ Sbjct: 641 REKVGVIVDVLSDTASNHNGFPVVEHADDTQPARLQGLILRSQLIVLLK 689 >gi|4502873 chloride channel 6 isoform ClC-6a [Homo sapiens] Length = 869 Score = 119 bits (299), Expect = 7e-27 Identities = 125/516 (24%), Positives = 220/516 (42%), Gaps = 76/516 (14%) Query: 114 ITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLS 173 I P + GSGIPE+K L GV + + ++ KV+G+ ++A G LF+GK GP +H Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207 Query: 174 VMIAAYLGRVRTTTIGEPE-------NKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEV 226 ++ A L + ++ ++ + + + + + + A AA GVA F AP G LFS+E Sbjct: 208 SVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEE 267 Query: 227 MSSHFSVRDYWRGFFAATCGAFI---------------FRLLAVFNSEQETITSLYKTSF 271 SS ++ W+ F + F F+L + N + + K Sbjct: 268 GSSFWNQGLTWKVLFCSMSATFTLNFFRSGIQFGSWGSFQLPGLLNFGEFKCSDSDKKCH 327 Query: 272 RVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRTFLSFIKTNRYSSKLLATSKPVYSALA 331 + ++ FFV +G I G+L + + + +Y + + + L Sbjct: 328 L----WTAMDLGFFVVMGVIGGLLGATFNCLNK------RLAKYRMRNVHPKPKLVRVLE 377 Query: 332 TLLLASITYPPGVGHFLASRL---SMKQHLDSLFDNHSWAL-MTQNSSPPWPEELDPQHL 387 +LL++ +T V F+AS + + S N S+ L +T++ + P Sbjct: 378 SLLVSLVT---TVVVFVASMVLGECRQMSSSSQIGNDSFQLQVTEDVNSSIKTFFCPN-- 432 Query: 388 WWEWYHPRFTIF--------------------GTLAFFLVMKFWMLILATTIPMPAGYFM 427 + Y+ T+F TLA F V+ F + I +P+G F+ Sbjct: 433 --DTYNDMATLFFNPQESAILQLFHQDGTFSPVTLALFFVLYFLLACWTYGISVPSGLFV 490 Query: 428 PIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGAAAFSGAVTH-TISTAL 486 P + GAA GRL+ L G I G +AL GAAAF G V TIS + Sbjct: 491 PSLLCGAAFGRLVANVLKSYIGLG--------HIYSGTFALIGAAAFLGGVVRMTISLTV 542 Query: 487 LAFELTGQIVHALPVLMAVLAANAIAQSCQPSFYDGTIIVKKLPYLPRILGRNIGSHHVR 546 + E T +I + LP+++ ++ A YD + ++ +P L + +R Sbjct: 543 ILIESTNEITYGLPIMVTLMVAKWTGDFFNKGIYDIHVGLRGVPLLE--WETEVEMDKLR 600 Query: 547 VEHFMNHSITTLAKDTPLEEVVKVVTSTDVTEYPLV 582 M ++T + T ++ +V ++ +T +P+V Sbjct: 601 ASDIMEPNLTYVYPHTRIQSLVSILRTTVHHAFPVV 636 >gi|12025671 chloride channel 6 isoform ClC-6c [Homo sapiens] Length = 353 Score = 72.8 bits (177), Expect = 1e-12 Identities = 45/142 (31%), Positives = 75/142 (52%), Gaps = 9/142 (6%) Query: 114 ITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLS 173 I P + GSGIPE+K L GV + + ++ KV+G+ ++A G LF+GK GP +H Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207 Query: 174 VMIAAYLGRVRTTTIGEPE-------NKSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEV 226 ++ A L + ++ ++ + + + + + + A AA GVA F AP G LFS+E Sbjct: 208 SVVGAGLPQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFSLEE 267 Query: 227 MSSHFSVRDYWRGFFAATCGAF 248 SS ++ W+ F + F Sbjct: 268 GSSFWNQGLTWKVLFCSMSATF 289 >gi|12025673 chloride channel 6 isoform ClC-6d [Homo sapiens] Length = 308 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/75 (34%), Positives = 45/75 (60%), Gaps = 2/75 (2%) Query: 114 ITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLS 173 I P + GSGIPE+K L GV + + ++ KV+G+ ++A G LF+GK GP +H Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207 Query: 174 VMIAAYLGRVRTTTI 188 ++ A L + ++ ++ Sbjct: 208 SVVGAGLPQFQSISL 222 >gi|12025668 chloride channel 6 isoform ClC-6b [Homo sapiens] Length = 320 Score = 47.8 bits (112), Expect = 3e-05 Identities = 26/75 (34%), Positives = 45/75 (60%), Gaps = 2/75 (2%) Query: 114 ITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGSTLFLGKVGPFVHLS 173 I P + GSGIPE+K L GV + + ++ KV+G+ ++A G LF+GK GP +H Sbjct: 150 IEPVAAGSGIPEVKCYLNGVKVPGIVRLRTLLCKVLGVLFSVAGG--LFVGKEGPMIHSG 207 Query: 174 VMIAAYLGRVRTTTI 188 ++ A L + ++ ++ Sbjct: 208 SVVGAGLPQFQSISL 222 >gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] Length = 4374 Score = 31.2 bits (69), Expect = 3.3 Identities = 18/48 (37%), Positives = 27/48 (56%) Query: 113 SITPSSGGSGIPELKTMLAGVILEDYLDIKNFGAKVVGLSCTLATGST 160 ++T SSG +G L T+L I+ED +++ KVV + T GST Sbjct: 1806 NLTQSSGFNGFTPLVTLLLRHIIEDPCTLRHTMEKVVRSAATSGAGST 1853 >gi|126352608 elastin isoform e precursor [Homo sapiens] Length = 705 Score = 30.8 bits (68), Expect = 4.4 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 420 PMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGA 471 P+P G + GA +G LG AV FP +V GGV + A AGA Sbjct: 65 PVPGG------LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA 110 >gi|126352446 elastin isoform d precursor [Homo sapiens] Length = 711 Score = 30.8 bits (68), Expect = 4.4 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 420 PMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGA 471 P+P G + GA +G LG AV FP +V GGV + A AGA Sbjct: 65 PVPGG------LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA 110 >gi|126352322 elastin isoform c precursor [Homo sapiens] Length = 692 Score = 30.8 bits (68), Expect = 4.4 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 420 PMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGA 471 P+P G + GA +G LG AV FP +V GGV + A AGA Sbjct: 65 PVPGG------LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA 110 >gi|126352700 elastin isoform b precursor [Homo sapiens] Length = 677 Score = 30.8 bits (68), Expect = 4.4 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 420 PMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGA 471 P+P G + GA +G LG AV FP +V GGV + A AGA Sbjct: 55 PVPGG------LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA 100 >gi|126352440 elastin isoform a precursor [Homo sapiens] Length = 724 Score = 30.8 bits (68), Expect = 4.4 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 420 PMPAGYFMPIFILGAAIGRLLGEALAVAFPEGIVTGGVTNPIMPGGYALAGA 471 P+P G + GA +G LG AV FP +V GGV + A AGA Sbjct: 65 PVPGG------LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA 110 >gi|156938237 ADP-ribosylation factor-like 17 isoform a [Homo sapiens] Length = 177 Score = 30.8 bits (68), Expect = 4.4 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Query: 194 KSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGA 247 K K E + A VG V + F++ + SHF +R W+ FF T GA Sbjct: 36 KLKLGETVPAVPTVGFC-VETVEYKNNTFAVWDVGSHFKIRPLWQHFFQNTKGA 88 >gi|166063999 hypothetical protein LOC51326 isoform a [Homo sapiens] Length = 177 Score = 30.8 bits (68), Expect = 4.4 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Query: 194 KSKQNEMLVAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVRDYWRGFFAATCGA 247 K K E + A VG V + F++ + SHF +R W+ FF T GA Sbjct: 36 KLKLGETVPAVPTVGFC-VETVEYKNNTFAVWDVGSHFKIRPLWQHFFQNTKGA 88 >gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sapiens] Length = 1176 Score = 29.6 bits (65), Expect = 9.7 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 10/59 (16%) Query: 397 TIFGTLAFFLVMKFWMLI---LATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGI 452 T+ + +F++ FW+ LA P+ YF+ FI+G + L VA PEG+ Sbjct: 384 TVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTV-------LVVAVPEGL 435 >gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sapiens] Length = 1220 Score = 29.6 bits (65), Expect = 9.7 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 10/59 (16%) Query: 397 TIFGTLAFFLVMKFWMLI---LATTIPMPAGYFMPIFILGAAIGRLLGEALAVAFPEGI 452 T+ + +F++ FW+ LA P+ YF+ FI+G + L VA PEG+ Sbjct: 384 TVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTV-------LVVAVPEGL 435 >gi|84508631 phosphatidylglycerophosphate synthase 1 [Homo sapiens] Length = 556 Score = 29.6 bits (65), Expect = 9.7 Identities = 16/63 (25%), Positives = 26/63 (41%) Query: 246 GAFIFRLLAVFNSEQETITSLYKTSFRVDVPFDLPEIFFFVALGGICGVLSCAYLFCQRT 305 GA ++ FN Q + + T + PE+ F G+ G + AY+ +R Sbjct: 379 GAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQ 438 Query: 306 FLS 308 F S Sbjct: 439 FFS 441 >gi|41349446 stromal interaction molecule 2 [Homo sapiens] Length = 833 Score = 29.6 bits (65), Expect = 9.7 Identities = 12/35 (34%), Positives = 19/35 (54%) Query: 345 GHFLASRLSMKQHLDSLFDNHSWALMTQNSSPPWP 379 G +A + SL+ +HSW +M + S PP+P Sbjct: 529 GFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYP 563 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.138 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,160,198 Number of Sequences: 37866 Number of extensions: 1050010 Number of successful extensions: 3400 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 4 Number of HSP's that attempted gapping in prelim test: 3300 Number of HSP's gapped (non-prelim): 44 length of query: 686 length of database: 18,247,518 effective HSP length: 109 effective length of query: 577 effective length of database: 14,120,124 effective search space: 8147311548 effective search space used: 8147311548 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.