Guide to the Human Genome
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Search of human proteins with 169211642

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169211642 PREDICTED: hypothetical protein [Homo sapiens]
         (378 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169211642 PREDICTED: hypothetical protein [Homo sapiens]           758   0.0  
gi|169210857 PREDICTED: similar to RIKEN cDNA E130309D14 [Homo s...   758   0.0  
gi|239756693 PREDICTED: similar to coiled-coil domain containing...   402   e-112
gi|13376725 coiled-coil domain containing 92 [Homo sapiens]            96   7e-20
gi|13994287 BTE-binding protein 4 [Homo sapiens]                       54   3e-07
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                52   1e-06
gi|154146199 sal-like 3 [Homo sapiens]                                 49   6e-06
gi|88196790 coiled-coil domain containing 88 [Homo sapiens]            47   2e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    47   3e-05
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     45   8e-05
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ...    45   1e-04
gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ...    45   1e-04
gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]      45   1e-04
gi|157785645 SPEG complex locus [Homo sapiens]                         45   1e-04
gi|239749124 PREDICTED: zinc finger protein 716 [Homo sapiens]         44   2e-04
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    44   2e-04
gi|59853099 dynamin 1 isoform 1 [Homo sapiens]                         44   2e-04
gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens]                      44   2e-04
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...    44   2e-04
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...    44   2e-04
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...    44   2e-04
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    44   2e-04
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]            44   3e-04
gi|239749482 PREDICTED: hypothetical protein [Homo sapiens]            44   3e-04
gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]            44   3e-04
gi|239743620 PREDICTED: hypothetical protein [Homo sapiens]            44   3e-04
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ...    43   4e-04
gi|242332545 coiled-coil domain containing 121-like [Homo sapiens]     43   4e-04
gi|169167297 PREDICTED: similar to hCG18094 [Homo sapiens]             43   4e-04

>gi|169211642 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 378

 Score =  758 bits (1956), Expect = 0.0
 Identities = 378/378 (100%), Positives = 378/378 (100%)

Query: 1   MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSGHGPDPKMWSRQEQSAL 60
           MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSGHGPDPKMWSRQEQSAL
Sbjct: 1   MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSGHGPDPKMWSRQEQSAL 60

Query: 61  THAMLLRWRRHLWQSPGSLEEPVRAVRRRGRGVTRPLKALLGGGPRDVPPSFPNPRFTPP 120
           THAMLLRWRRHLWQSPGSLEEPVRAVRRRGRGVTRPLKALLGGGPRDVPPSFPNPRFTPP
Sbjct: 61  THAMLLRWRRHLWQSPGSLEEPVRAVRRRGRGVTRPLKALLGGGPRDVPPSFPNPRFTPP 120

Query: 121 PRGHQTVSLQVYTELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRRE 180
           PRGHQTVSLQVYTELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRRE
Sbjct: 121 PRGHQTVSLQVYTELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRRE 180

Query: 181 VAQREALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQR 240
           VAQREALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQR
Sbjct: 181 VAQREALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQR 240

Query: 241 LQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAA 300
           LQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAA
Sbjct: 241 LQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAA 300

Query: 301 RSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGH 360
           RSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGH
Sbjct: 301 RSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGH 360

Query: 361 LLYREDSPSRSWPGPTCL 378
           LLYREDSPSRSWPGPTCL
Sbjct: 361 LLYREDSPSRSWPGPTCL 378


>gi|169210857 PREDICTED: similar to RIKEN cDNA E130309D14 [Homo
           sapiens]
          Length = 378

 Score =  758 bits (1956), Expect = 0.0
 Identities = 378/378 (100%), Positives = 378/378 (100%)

Query: 1   MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSGHGPDPKMWSRQEQSAL 60
           MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSGHGPDPKMWSRQEQSAL
Sbjct: 1   MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCSGHGPDPKMWSRQEQSAL 60

Query: 61  THAMLLRWRRHLWQSPGSLEEPVRAVRRRGRGVTRPLKALLGGGPRDVPPSFPNPRFTPP 120
           THAMLLRWRRHLWQSPGSLEEPVRAVRRRGRGVTRPLKALLGGGPRDVPPSFPNPRFTPP
Sbjct: 61  THAMLLRWRRHLWQSPGSLEEPVRAVRRRGRGVTRPLKALLGGGPRDVPPSFPNPRFTPP 120

Query: 121 PRGHQTVSLQVYTELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRRE 180
           PRGHQTVSLQVYTELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRRE
Sbjct: 121 PRGHQTVSLQVYTELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRRE 180

Query: 181 VAQREALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQR 240
           VAQREALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQR
Sbjct: 181 VAQREALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQR 240

Query: 241 LQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAA 300
           LQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAA
Sbjct: 241 LQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAA 300

Query: 301 RSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGH 360
           RSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGH
Sbjct: 301 RSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGH 360

Query: 361 LLYREDSPSRSWPGPTCL 378
           LLYREDSPSRSWPGPTCL
Sbjct: 361 LLYREDSPSRSWPGPTCL 378


>gi|239756693 PREDICTED: similar to coiled-coil domain containing 92
           [Homo sapiens]
          Length = 272

 Score =  402 bits (1033), Expect = e-112
 Identities = 212/240 (88%), Positives = 214/240 (89%), Gaps = 18/240 (7%)

Query: 139 LEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTE 198
           LE+   Q    EAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTE
Sbjct: 51  LEILRLQKRCSEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTE 110

Query: 199 ERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAAAQRPQPAPAASPG 258
           ERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQA     P+P PA    
Sbjct: 111 ERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQA-----PRPGPA---- 161

Query: 259 APGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRK 318
                    RAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRK
Sbjct: 162 ---------RAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRK 212

Query: 319 RGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDSPSRSWPGPTCL 378
           RGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDSPSRSWPGPTCL
Sbjct: 213 RGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYREDSPSRSWPGPTCL 272



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 43/43 (100%), Positives = 43/43 (100%)

Query: 1  MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCS 43
          MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCS
Sbjct: 19 MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCS 61


>gi|13376725 coiled-coil domain containing 92 [Homo sapiens]
          Length = 331

 Score = 95.5 bits (236), Expect = 7e-20
 Identities = 47/148 (31%), Positives = 91/148 (61%), Gaps = 4/148 (2%)

Query: 133 TELTHDLEMREA-QSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSAL 191
           T+LT++L ++ + Q+    + S EL+ +C  LE+QL+ +   NAEL +E+ Q+ A+++ L
Sbjct: 60  TDLTYELTVKSSEQTGDGTSKSSELKKRCEELEAQLKVKENENAELLKELEQKNAMITVL 119

Query: 192 RCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAAA---QR 248
             +++  E+++LEEL+ +SH+ T+L +EL++     AYL+ QLHAA+++L +++      
Sbjct: 120 ENTIKEREKKYLEELKAKSHKLTLLSSELEQRASTIAYLTSQLHAAKKKLMSSSGTSDAS 179

Query: 249 PQPAPAASPGAPGPSRPAARAQPAQRAR 276
           P  +P  +   P P +      P +R +
Sbjct: 180 PSGSPVLASYKPAPPKDKLPETPRRRMK 207



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 18/43 (41%), Positives = 30/43 (69%)

Query: 1  MDTVSLEHQIQSVQRHISFLKKEQMALLRDLHLEILRLQKRCS 43
          M   +LE+Q+ S Q+++ FL++E  + L+ LH EI RLQ+ C+
Sbjct: 18 MAATNLENQLHSAQKNLLFLQREHASTLKGLHSEIRRLQQHCT 60


>gi|13994287 BTE-binding protein 4 [Homo sapiens]
          Length = 252

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 41/107 (38%), Positives = 48/107 (44%), Gaps = 14/107 (13%)

Query: 241 LQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGAR----LAGVTRDGRGGPA 296
           L   AA+R     AASPG PGP  P     PA    GPG  A      A +  D RGGP 
Sbjct: 41  LDVRAARRE----AASPGTPGPPPPP----PAASGPGPGAAAAPHLLAASILADLRGGPG 92

Query: 297 RDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKA 343
                +  A   S  S PSS +   AAP+     +R PF  PD +KA
Sbjct: 93  AAPGGASPASSSSAASSPSSGRAPGAAPSAAAKSHRCPF--PDCAKA 137


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 64/238 (26%), Positives = 94/238 (39%), Gaps = 23/238 (9%)

Query: 133  TELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALR 192
            T L  +L   + +    E A +E   +   L  +L    A+   +R+E+   +  +    
Sbjct: 1297 TRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQE 1356

Query: 193  CSLRTEERRFLEEL-------RRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAA 245
               RT ERR L  L       +++   A  L  +L+     AA L  +L AA  R Q   
Sbjct: 1357 GEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLE 1416

Query: 246  AQ--RPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSP 303
            A+  R +    A+    G  R A R       RG G+G   +   R   G PARDA   P
Sbjct: 1417 AELARVEVQRRAAEAQLGGLRSALR-------RGLGLGRAPSPAPRPVPGSPARDA---P 1466

Query: 304  QAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREF---LRGAER 358
              G G   + PS+ +    +  P   P   P   PD+   +     REF   LR A+R
Sbjct: 1467 AEGSGEGLNSPSTLECSPGSQPPSPGPATSP-ASPDLDPEAVRGALREFLQELRSAQR 1523



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 67/249 (26%), Positives = 98/249 (39%), Gaps = 38/249 (15%)

Query: 134  ELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRC 193
            EL   ++M ++++ +      EL+ +    E   +        LR+ + + EA +  +R 
Sbjct: 1284 ELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQ 1343

Query: 194  SLRTEERRFLE---ELRRRSHRAT-----VLGTELQKHTEAAAYLSCQLHAARQRLQAAA 245
             L+  +R+  E   E R R  R         GTE Q+   A   L  +L AAR    A A
Sbjct: 1344 ELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARG-LELKLEAAR----AEA 1398

Query: 246  AQRPQPAPAASPGAPGPSRPAARAQPAQRA-------------RGPGVGARLAGVTRDGR 292
            A+      AA   A G     AR +  +RA             RG G+G   +   R   
Sbjct: 1399 AELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPVP 1458

Query: 293  GGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREF 352
            G PARDA   P  G G   + PS+ +    +  P   P   P         +SP L  E 
Sbjct: 1459 GSPARDA---PAEGSGEGLNSPSTLECSPGSQPPSPGPATSP---------ASPDLDPEA 1506

Query: 353  LRGAERGHL 361
            +RGA R  L
Sbjct: 1507 VRGALREFL 1515



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 48/186 (25%), Positives = 68/186 (36%), Gaps = 42/186 (22%)

Query: 138 DLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALR----- 192
           +LE+   +   +EA+ ++  SK  AL   L   A    +L R VAQ E   SAL+     
Sbjct: 719 ELELSMTKLRAEEASLQDSLSKLSALNESL---AQDKLDLNRLVAQLEEEKSALQGRQRQ 775

Query: 193 ----CSLRTEERRFLEELRRRSHRA----------------------TVLGTELQKHTEA 226
                ++  EE+  LEELR     A                        L  E  +  E 
Sbjct: 776 AEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQ 835

Query: 227 AAYLSCQLHAARQRLQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAG 286
            A LS QL    Q L+ A  +  +   A           AAR + A      G+  +L  
Sbjct: 836 LAQLSRQLSGREQELEQARREAQRQVEAL--------ERAAREKEALAKEHAGLAVQLVA 887

Query: 287 VTRDGR 292
             R+GR
Sbjct: 888 AEREGR 893



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 35/122 (28%), Positives = 50/122 (40%), Gaps = 5/122 (4%)

Query: 122 RGHQTVSLQVYTELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREV 181
           +G Q  + Q  T    + E  E    +QE A + LE   R  E   EA       LR E 
Sbjct: 770 QGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHER 829

Query: 182 AQREALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAY----LSCQLHAA 237
           +Q +  ++ L   L   E+  LE+ RR + R         +  EA A     L+ QL AA
Sbjct: 830 SQLQEQLAQLSRQLSGREQE-LEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAA 888

Query: 238 RQ 239
            +
Sbjct: 889 ER 890



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 42/164 (25%), Positives = 64/164 (39%), Gaps = 14/164 (8%)

Query: 137  HDLEMREAQSHQQEAASRELESKCRALESQLEAR--------AAANAELRREVAQREALV 188
            H+ +++  Q  ++EAA RELE++   L+SQL+           A   EL  E+A   AL 
Sbjct: 991  HEEDLQRLQ-REKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIA---ALQ 1046

Query: 189  SALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAAAQR 248
                  L   E    + L  +    T L  +L     + A +S ++   ++  Q+   Q 
Sbjct: 1047 QERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD 1106

Query: 249  PQPAPAASPGAPG--PSRPAARAQPAQRARGPGVGARLAGVTRD 290
                 A +         R  A A  AQ  R     AR  G  RD
Sbjct: 1107 RSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRD 1150



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 8/84 (9%)

Query: 126  TVSLQVYTELTHDLEMREAQSHQQEAAS--RELESKCRALESQLEARAAANAELRREVAQ 183
            T+SL++      + + R+AQS Q++  S    L S+ R L +Q E  AAA+A+  R + +
Sbjct: 1087 TISLEM------ERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQE 1140

Query: 184  REALVSALRCSLRTEERRFLEELR 207
            +   +   R S   E      +LR
Sbjct: 1141 QARDLGKQRDSCLREAEELRTQLR 1164


>gi|154146199 sal-like 3 [Homo sapiens]
          Length = 1300

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 43/132 (32%), Positives = 49/132 (37%), Gaps = 13/132 (9%)

Query: 240 RLQAAAAQRPQPAPAASPGA-PGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARD 298
           R Q A  QRP P P+ SP A P    PA    P   A     GA  A +   G   PA  
Sbjct: 227 RSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAF 286

Query: 299 AARSPQAGPGSEGSRPS-----------SRKRGEAAPAPPKSPNRQPFVLPDVSKASSPL 347
               P + P S  S P            S     AAPAP  +P       P  S ++ P 
Sbjct: 287 EGAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQ-SASTPPA 345

Query: 348 LAREFLRGAERG 359
           LA   L GA  G
Sbjct: 346 LAPGSLLGAAPG 357



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 10/70 (14%)

Query: 249 PQPAPAASPGAPGPSRPA---------ARAQPAQRARGPGVGARLAGVTRDGRGGPARDA 299
           P+P+PA+SP     S  A           A+P ++   P + A  AG TR  R  PA  A
Sbjct: 95  PEPSPASSPSERAESEAAEEAGAEGAEGEARPVEKEAEP-MDAEPAGDTRAPRPPPAAPA 153

Query: 300 ARSPQAGPGS 309
             +P  G  S
Sbjct: 154 PPTPAYGAPS 163


>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
          Length = 1476

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 41/122 (33%), Positives = 58/122 (47%), Gaps = 15/122 (12%)

Query: 143 EAQSHQQ-------EAASRELESKCRALESQLEARAAANAELR-------REVAQREALV 188
           EAQ+ +Q       EAA +ELES  +  E+ +EA AAA  E R       R  AQ EA  
Sbjct: 784 EAQAWEQARLREAVEAAGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAE 843

Query: 189 SALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAAAQR 248
             ++  L +E R+ LEE  R       L  EL+K       L  +L   ++ L+ AA +R
Sbjct: 844 ERMQV-LESEGRQHLEEAERERREKEALQAELEKAVVRGKELGARLEHLQRELEQAALER 902

Query: 249 PQ 250
            +
Sbjct: 903 QE 904



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 90/366 (24%), Positives = 126/366 (34%), Gaps = 65/366 (17%)

Query: 47  PDPKMWSRQEQSALTHAMLL---RWRRHLWQSPGSLEEPVRAVRRRGRGVTRPLKALLGG 103
           P    WS QE  +            RR   QSP S+  P      +G G       LLGG
Sbjct: 569 PQASDWSPQESGSPVETQESPEKAGRRSSLQSPASVAPP------QGPGTKIQAPQLLGG 622

Query: 104 GPRD--------VPPSF----PNPRFTPPPRGHQTVSLQVYTELTHDLEMREAQSHQQEA 151
                       VP ++      P   P P    +V L+        L++   Q+  +E 
Sbjct: 623 ETEGREAPQGELVPEAWGLRQEGPEHKPGPSEPSSVQLEEQEGPNQGLDLATGQAEAREH 682

Query: 152 ASRELESKCR-------------ALESQL-------EARAAANAE---LRREVAQ----R 184
             R LE   R             ALE Q+       E+ A+  AE   LR EVAQ     
Sbjct: 683 DQR-LEGTVRDPAWQKPQQKSEGALEVQVWEGPIPGESLASGVAEQEALREEVAQLRRKA 741

Query: 185 EALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAY------LSCQLHAAR 238
           EAL   L    R  E +  E  R     A     E + H EA A       L   + AA 
Sbjct: 742 EALGDELEAQARKLEAQNTEAARLSKELAQARRAEAEAHREAEAQAWEQARLREAVEAAG 801

Query: 239 QRLQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARD 298
           Q L++A+ +R +    A   A    R   R     RA+      R+  +  +GR     +
Sbjct: 802 QELESASQER-EALVEALAAAGRERRQWEREGSRLRAQSEAAEERMQVLESEGR-QHLEE 859

Query: 299 AARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAER 358
           A R  +     +     +  RG+   A  +   R+           + L  +EFLR  E 
Sbjct: 860 AERERREKEALQAELEKAVVRGKELGARLEHLQRE--------LEQAALERQEFLREKES 911

Query: 359 GHLLYR 364
            H  Y+
Sbjct: 912 QHQRYQ 917



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 46/197 (23%), Positives = 70/197 (35%), Gaps = 24/197 (12%)

Query: 139  LEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTE 198
            LE+  AQ   Q    RE   +      +L  +     +LR    +    + A   +L  E
Sbjct: 1196 LELERAQLEMQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRE 1255

Query: 199  ERRFLE-ELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAAAQ--------RP 249
             R  LE  L  R H           H E   YL  QL+A R+  Q    +         P
Sbjct: 1256 NRELLERSLESRDH----------LHREQREYLD-QLNALRREKQKLVEKIMDQYRVLEP 1304

Query: 250  QPAPAASPGAPGPSRPAARAQPAQRARGPG---VGARLAGVTRDGRGGPARDAARSPQAG 306
             P P    G+    +     +P +    PG   +GA  AG T +  GGP        +  
Sbjct: 1305 VPLPRTKKGSWLADKVKRLMRPRREGGPPGGLRLGADGAGST-ESLGGPPETELPEGREA 1363

Query: 307  PGSEGSRPSSRKRGEAA 323
             G+    P+  +R +++
Sbjct: 1364 DGTGSPSPAPMRRAQSS 1380



 Score = 32.3 bits (72), Expect = 0.72
 Identities = 28/108 (25%), Positives = 45/108 (41%), Gaps = 5/108 (4%)

Query: 143 EAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEERRF 202
           E  SH         +++ R L  +LE +A    + + EV   EA +  LR     +E + 
Sbjct: 250 EGPSHHLALQLANAKAQLRRLRQELEEKAELLLDSQAEVQGLEAEIRRLR-----QEAQA 304

Query: 203 LEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAAAQRPQ 250
           L    +R+         L++       L  +L   R+RLQAA A + Q
Sbjct: 305 LSGQAKRAELYREEAEALRERAGRLPRLQEELRRCRERLQAAEAYKSQ 352



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 17/127 (13%)

Query: 122  RGHQTVSLQVYTELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREV 181
            RG Q   L+ +  L      +EA+        R+L++  RALE              RE+
Sbjct: 1068 RGQQQALLRDHKALAQLQRRQEAELEGLLVRHRDLKANMRALEL-----------AHREL 1116

Query: 182  AQREALVSALRCSLRTEERRFL---EELRRRSHRATVLGTE---LQKHTEAAAYLSCQLH 235
              R   + A R S+  +E   L   E L +  HR   L  E   LQ   + A  L  +L 
Sbjct: 1117 QGRHEQLQAQRASVEAQEVALLAERERLMQDGHRQRGLEEELRRLQSEHDRAQMLLAELS 1176

Query: 236  AARQRLQ 242
              R  LQ
Sbjct: 1177 RERGELQ 1183


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 38/119 (31%), Positives = 49/119 (41%), Gaps = 11/119 (9%)

Query: 251  PAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARS----PQAG 306
            P+P  SPG P P    A   PA     P     L   T   +GGP   +++     P A 
Sbjct: 1318 PSPKGSPGTPPPK--GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375

Query: 307  PGSEGS---RPSSRKRGEAAPAPPKSPNRQPFVLP-DVSKASSPLLAREFLRGAERGHL 361
            P  +G     P S KRG A P+P   P   P V+P    KA +  + RE      +G L
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPT-SPAVIPLSPKKAPATPVTREGAATPSKGDL 1433



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 26/110 (23%)

Query: 249  PQPAPAASPGAP--GPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAG 306
            P P PAA+P +P  GP+ P+ +  P   A  P             +GGPA     SP+  
Sbjct: 940  PTP-PAATPPSPKGGPATPSPKWAPTPPAATPP----------SPKGGPATP---SPKGA 985

Query: 307  PGSEGSRPSSRKRGEAAPAP----------PKSPNRQPFVLPDVSKASSP 346
            P    + P S K G A P+P          P SP   P   P    AS+P
Sbjct: 986  PTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 28/94 (29%), Positives = 37/94 (39%), Gaps = 9/94 (9%)

Query: 243  AAAAQRPQPAPAASPGAPGPSRPAA------RAQPAQRARGPGVGARLAGVTRDGRGGPA 296
            A     P+ +PAA+P   G S P A      +  PA      G     A      +GGPA
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA 1072

Query: 297  RDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSP 330
                 S +  P    + P S K G A P+P  +P
Sbjct: 1073 TP---SLKGAPTPPAATPPSPKGGPATPSPKGAP 1103



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 3/85 (3%)

Query: 253  PAASPGAP--GPSRPAARAQPAQ-RARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGS 309
            PAA+P +P  GP+ P  +  P    A  P +   LA     G   PA     SP+ GP +
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303

Query: 310  EGSRPSSRKRGEAAPAPPKSPNRQP 334
               + +        P+P  SP   P
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPP 1328



 Score = 37.0 bits (84), Expect = 0.029
 Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 16/98 (16%)

Query: 249  PQPAPAASPGAP--GPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAG 306
            P P PAA+P +P  GP+ P+ +  P   A  P             +GGPA     SP+  
Sbjct: 963  PTP-PAATPPSPKGGPATPSPKGAPTPPAATPP----------SPKGGPATP---SPKGA 1008

Query: 307  PGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKAS 344
            P      P S K   AA   PK  +  P   P   K S
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046



 Score = 35.4 bits (80), Expect = 0.085
 Identities = 34/111 (30%), Positives = 41/111 (36%), Gaps = 8/111 (7%)

Query: 243  AAAAQRPQPAPAASPGAPGPSRPAARAQPAQ--RARGPGVGARLAGVTR--DGRGGPARD 298
            AA    P+  PA  P    P+ PAA     +   A  P  GA    V      +GGP   
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP--- 1301

Query: 299  AARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLA 349
            A   P+  P    + P S K     P PPK     P V P   K +  L A
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTP-PPKGAPTPPAVTPPSPKGTPTLPA 1351



 Score = 33.1 bits (74), Expect = 0.42
 Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 18/121 (14%)

Query: 245  AAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQ 304
            A   P+ AP  +P A  PS     A P+ +    G     A      +GG A     SP+
Sbjct: 1164 ATPPPKGAPT-TPAATPPSPKGGLATPSPK----GAPTTPAATPPSPKGGLATP---SPK 1215

Query: 305  AGPGSEGSRPSSRKRGEAAPAP----------PKSPNRQPFVLPDVSKASSPLLAREFLR 354
              P +  + P S K G A P+P          P SP   P   P     + P      L+
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK 1275

Query: 355  G 355
            G
Sbjct: 1276 G 1276



 Score = 33.1 bits (74), Expect = 0.42
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 11/102 (10%)

Query: 251  PAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSE 310
            PAP ++P    P+R   + + +     P      A   ++G  GP    A +P      +
Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA---KNGSKGPLSTVAPAPLLPVQKD 1744

Query: 311  GSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREF 352
             S+ +   +G+ A   PK P     + P  SKAS+PL A  F
Sbjct: 1745 SSKTA---KGKDASHSPKGP-----LAPPESKASTPLTAAAF 1778



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 22/100 (22%)

Query: 242 QAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAAR 301
           +  A   P+ APA S  +  P +  ARA PA +    G+ A     +   +G P   AA 
Sbjct: 898 EGPATPAPKQAPALSMTSSSPKK--ARATPAPK----GIPA-----SPSPKGAPTPPAAT 946

Query: 302 --SPQAGPGSEGSR---------PSSRKRGEAAPAPPKSP 330
             SP+ GP +   +         P S K G A P+P  +P
Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 2/80 (2%)

Query: 251  PAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSE 310
            P+P  +P  P  + P+ +  PA      G     A      +G PA  A   P+  P + 
Sbjct: 1003 PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA--ATPLPKGAPTTP 1060

Query: 311  GSRPSSRKRGEAAPAPPKSP 330
             +   S K G A P+   +P
Sbjct: 1061 AATLPSPKGGPATPSLKGAP 1080



 Score = 32.0 bits (71), Expect = 0.94
 Identities = 27/100 (27%), Positives = 36/100 (36%), Gaps = 11/100 (11%)

Query: 251  PAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPAR------DAARSPQ 304
            P+P  +P  P P    A     + +  P V       T  G   P          + SP+
Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASSPPAVTPS----TYKGAPSPKELLIPPAVTSPSPK 1611

Query: 305  AGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKAS 344
              P      P S ++G A PAP  +P   P V P   K S
Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTSPP-VTPSSLKDS 1650



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 9/101 (8%)

Query: 235  HAARQRLQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQR---ARGPGVGARL--AGVTR 289
            H       AA    P+   A  P    P+ PAA   P+ +   A  P  GA    A    
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA-TPPSPKGGLATPPPKGAPTTPAATPP 1180

Query: 290  DGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSP 330
              +GG A     SP+  P +  + P S K G A P+P  +P
Sbjct: 1181 SPKGGLATP---SPKGAPTTPAATPPSPKGGLATPSPKGAP 1218



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 33/123 (26%), Positives = 50/123 (40%), Gaps = 25/123 (20%)

Query: 244  AAAQRPQPAPAASPGAP--GPSRPAARAQPAQRARGP--GVGARLAGVTRDGRGGPARD- 298
            AA    +  PA +P +P  GP+ P+ +  P   A  P     A    VTR+G   P++  
Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432

Query: 299  ---------------AARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKA 343
                           A  +P+ GP +    PSS+         P SP ++P     V+ +
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPAT----PSSKGDPTLPAVTPPSP-KEPPAPKQVATS 1487

Query: 344  SSP 346
            SSP
Sbjct: 1488 SSP 1490


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 60/240 (25%), Positives = 81/240 (33%), Gaps = 33/240 (13%)

Query: 109 PPSFPNPRFTPPPRGHQTVSLQVYTELTHDLEMREAQSHQQEAASRELESKCRALESQLE 168
           PP+ P P            S    +    +  +    S +   A  +LE  CR +  +  
Sbjct: 4   PPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHG 63

Query: 169 ARAA-ANAELRREVAQREALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAA 227
                  AEL + + QR  L  + + S+       ++  RR                   
Sbjct: 64  PEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRR------------------G 105

Query: 228 AYLSCQLHAARQRLQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGV 287
           A       A R    AAAA  P P PA  P    P  P A A PA+  R     A  A  
Sbjct: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPPP----PPAPVAAAAPARAPR-----AAAAAA 156

Query: 288 TRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPL 347
           T     GPA+   R+ +A P    + P        A APP  P R P   P V+    PL
Sbjct: 157 TAPPSPGPAQPGPRAQRAAP---LAAPPPAPAAPPAVAPPAGPRRAP--PPAVAAREPPL 211



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 24/104 (23%)

Query: 264 RPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGS-------EGSRPSS 316
           R AAR QP +R      GA      R  RG PA  AA +P   P           + P+ 
Sbjct: 94  RNAARVQPPRR------GATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR 147

Query: 317 RKRGEAA-----PAP------PKSPNRQPFVLPDVSKASSPLLA 349
             R  AA     P+P      P++    P   P  + A+ P +A
Sbjct: 148 APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVA 191


>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
           sapiens]
          Length = 384

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 49/161 (30%), Positives = 60/161 (37%), Gaps = 41/161 (25%)

Query: 245 AAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQ 304
           AA R    P   PG P  SRP           G G GAR  G    G GGP   AA SP 
Sbjct: 191 AAPRRSARPFRRPGLPLKSRP-----------GSGTGARSCGTWGSG-GGPGTAAASSPS 238

Query: 305 AGPGSEGSRP-------------SSRKRGEA----------APAPPKSPNRQPFVLP--- 338
           A   S+  +P               R+R             +PAPP+   R+P  L    
Sbjct: 239 ADFSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYRKPLTLSFGG 298

Query: 339 DVSKASSPLLA--REFLRGAERGHLLYREDSPSRSWPGPTC 377
            VS  + P++A  R F R   R    +R  S   + P P C
Sbjct: 299 GVSSPTHPVVAPRRHFPRSVPRFPAGFRTHSLGTA-PKPKC 338



 Score = 35.4 bits (80), Expect = 0.085
 Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 235 HAARQRLQAAAAQRPQPAPAASPGAPGPSRP--AARAQPAQRAR-GPGVGARLAGVTRDG 291
           H +  RL+ AA   P+P  +++  +P P+ P  AAR  P + A  G G G+R  G  + G
Sbjct: 113 HQSGSRLRPAAPG-PRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVG 171

Query: 292 RGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAR 350
              P+R   + P          P + +R  AAP     P R+P  LP  S+  S   AR
Sbjct: 172 -ARPSRAGGQPP----------PLTCRRCRAAPRRSARPFRRP-GLPLKSRPGSGTGAR 218


>gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo
           sapiens]
          Length = 384

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 49/161 (30%), Positives = 60/161 (37%), Gaps = 41/161 (25%)

Query: 245 AAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQ 304
           AA R    P   PG P  SRP           G G GAR  G    G GGP   AA SP 
Sbjct: 191 AAPRRSARPFRRPGLPLKSRP-----------GSGTGARSCGTWGSG-GGPGTAAASSPS 238

Query: 305 AGPGSEGSRP-------------SSRKRGEA----------APAPPKSPNRQPFVLP--- 338
           A   S+  +P               R+R             +PAPP+   R+P  L    
Sbjct: 239 ADFSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYRKPLTLSFGG 298

Query: 339 DVSKASSPLLA--REFLRGAERGHLLYREDSPSRSWPGPTC 377
            VS  + P++A  R F R   R    +R  S   + P P C
Sbjct: 299 GVSSPTHPVVAPRRHFPRSVPRFPAGFRTHSLGTA-PKPKC 338



 Score = 35.4 bits (80), Expect = 0.085
 Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 235 HAARQRLQAAAAQRPQPAPAASPGAPGPSRP--AARAQPAQRAR-GPGVGARLAGVTRDG 291
           H +  RL+ AA   P+P  +++  +P P+ P  AAR  P + A  G G G+R  G  + G
Sbjct: 113 HQSGSRLRPAAPG-PRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVG 171

Query: 292 RGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAR 350
              P+R   + P          P + +R  AAP     P R+P  LP  S+  S   AR
Sbjct: 172 -ARPSRAGGQPP----------PLTCRRCRAAPRRSARPFRRP-GLPLKSRPGSGTGAR 218


>gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 49/161 (30%), Positives = 60/161 (37%), Gaps = 41/161 (25%)

Query: 245 AAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQ 304
           AA R    P   PG P  SRP           G G GAR  G    G GGP   AA SP 
Sbjct: 191 AAPRRSARPFRRPGLPLKSRP-----------GSGTGARSCGTWGSG-GGPGTAAASSPS 238

Query: 305 AGPGSEGSRP-------------SSRKRGEA----------APAPPKSPNRQPFVLP--- 338
           A   S+  +P               R+R             +PAPP+   R+P  L    
Sbjct: 239 ADFSSDSPQPIIIFGGALRVRGCGGRRRSNGQGTQPGCRLLSPAPPRRRYRKPLTLSFGG 298

Query: 339 DVSKASSPLLA--REFLRGAERGHLLYREDSPSRSWPGPTC 377
            VS  + P++A  R F R   R    +R  S   + P P C
Sbjct: 299 GVSSPTHPVVAPRRHFPRSVPRFPAGFRTHSLGTA-PKPKC 338



 Score = 35.4 bits (80), Expect = 0.085
 Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 16/119 (13%)

Query: 235 HAARQRLQAAAAQRPQPAPAASPGAPGPSRP--AARAQPAQRAR-GPGVGARLAGVTRDG 291
           H +  RL+ AA   P+P  +++  +P P+ P  AAR  P + A  G G G+R  G  + G
Sbjct: 113 HQSGSRLRPAAPG-PRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVG 171

Query: 292 RGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAR 350
              P+R   + P          P + +R  AAP     P R+P  LP  S+  S   AR
Sbjct: 172 -ARPSRAGGQPP----------PLTCRRCRAAPRRSARPFRRP-GLPLKSRPGSGTGAR 218


>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
          Length = 1312

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 60/263 (22%), Positives = 95/263 (36%), Gaps = 21/263 (7%)

Query: 135 LTHDLEMREAQSHQQEAASREL-ESKCRALESQLEARAAANAELRREVAQR-------EA 186
           L    ++++ Q    EA  + L   + R +E Q E R     + RRE  QR       + 
Sbjct: 369 LKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQR 428

Query: 187 LVSALRCSLRTEERRFLE---ELRRRSHRATVLGTELQKHTEAA-AYL-SCQLHAARQRL 241
            +  ++   R EERR  E   E +R+          LQ+  +   AYL S Q    +Q+L
Sbjct: 429 RLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQL 488

Query: 242 QAAAAQRPQPAPAA-----SPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPA 296
           Q    Q+  P           G     +PA   +  +R R           ++ G  GP 
Sbjct: 489 QKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPE 548

Query: 297 RDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQP---FVLPDVSKASSPLLAREFL 353
               ++    PG     P  ++  E    P KS   QP         S    P +     
Sbjct: 549 PPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLQDQPTRNLAAFPASHDPDPAIPAPTA 608

Query: 354 RGAERGHLLYREDSPSRSWPGPT 376
             + RG ++ +   P+   PGP+
Sbjct: 609 TPSARGAVIRQNSDPTSEGPGPS 631



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 46/209 (22%), Positives = 80/209 (38%), Gaps = 19/209 (9%)

Query: 145 QSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCS-----LRTEE 199
           +  ++  A RE E K + LE Q ++       L+R++ Q  A + +L+       L+ ++
Sbjct: 438 REEERRQAEREQEYKRKQLEEQRQSE-----RLQRQLQQEHAYLKSLQQQQQQQQLQKQQ 492

Query: 200 RRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAAAQRPQ---PAPAAS 256
           ++ L    R+       G         A  +  +    +Q+    A  +P    P P   
Sbjct: 493 QQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIP 552

Query: 257 PGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSS 316
             +PGP  P ++  P QR   P  G   +   +  R   A  A+  P     +  + PS+
Sbjct: 553 QASPGPPGPLSQTPPMQRPVEPQEGPHKSLQDQPTRNLAAFPASHDPDPAIPAPTATPSA 612

Query: 317 R------KRGEAAPAPPKSPNRQPFVLPD 339
           R           +  P  SPN   +V PD
Sbjct: 613 RGAVIRQNSDPTSEGPGPSPNPPAWVRPD 641


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 65/234 (27%), Positives = 88/234 (37%), Gaps = 30/234 (12%)

Query: 148 QQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEERRFLEELR 207
           QQ+AAS +  ++ R+  S LE R A      R    RE LV            R  E LR
Sbjct: 471 QQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELV------------RSHESLR 518

Query: 208 RRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAAAQRPQPAPAASPGAPGPSRPAA 267
               RA       ++  E   +         + +  AAAQ P P+ A  PG   P RP +
Sbjct: 519 ATLQRA----PSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPG-DEPGRPRS 573

Query: 268 RAQPAQRARGPGVGARLAGVTRDG---RGGPARDAARSPQAGPGSEGSRPSSRKR---GE 321
           R  PA R   PG G +     RD        A    RSP   P ++   P +R +   G 
Sbjct: 574 RG-PAGRTE-PGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPAAD--PPEARTKAPPGR 629

Query: 322 AAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGAERGHLLYR---EDSPSRSW 372
               P ++    P+  P +  A+ P    +   G E    L R   ED P   W
Sbjct: 630 KREPPAQAVRFLPWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGPW 683



 Score = 37.0 bits (84), Expect = 0.029
 Identities = 36/115 (31%), Positives = 45/115 (39%), Gaps = 11/115 (9%)

Query: 249 PQPAPAASPGAPGPSRPAARAQ--PAQRAR-----GPGV-GARLAGVTRDGRGGPARDAA 300
           P P PAA P       P  R +  PAQ  R      PG+ GA +       R GP  +  
Sbjct: 610 PVPPPAADPPEARTKAPPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKNRAGPEAEKR 669

Query: 301 --RSPQA-GPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREF 352
             R P+  GP     R  +R +G+   A P SP  +      VS    PL A  F
Sbjct: 670 LRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPELESSDDSYVSAGEEPLEAPVF 724



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 48/190 (25%), Positives = 66/190 (34%), Gaps = 31/190 (16%)

Query: 186 ALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAAA 245
           AL S  R  LR E  R    L  R  RA   G+ +   T      +C   AA   ++   
Sbjct: 761 ALRSEGRLLLRAEGER--HTLLLREARAADAGSYMATATNELGQATC---AASLTVRPGG 815

Query: 246 AQRPQPAPAAS-------------PGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGR 292
           +  P  +P  S             PG   P  P  +  P+Q  R    G+         +
Sbjct: 816 STSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGS---------K 866

Query: 293 GGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPL---LA 349
             P    +   Q+    +    S R +GE  P      NRQP V PD  + +      L 
Sbjct: 867 APPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQP-VRPDQRRFAEEAEGGLC 925

Query: 350 REFLRGAERG 359
           R  +  AERG
Sbjct: 926 RLRILAAERG 935


>gi|239749124 PREDICTED: zinc finger protein 716 [Homo sapiens]
          Length = 1215

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 35/95 (36%), Positives = 42/95 (44%), Gaps = 9/95 (9%)

Query: 239 QRLQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARD 298
           Q  +A A    +PA A     P P RPAAR +   R   P  G + AG    G GGPAR 
Sbjct: 67  QHRRAVARLPAEPAHAV----PHPVRPAARLRAPARDPVPLAGRQRAGAAPRGPGGPART 122

Query: 299 ----AARSPQAGPGSEGSRPS-SRKRGEAAPAPPK 328
               A R    GPG E   P  +R  G + P  P+
Sbjct: 123 PAVRAGRRAADGPGEEAPAPGRARFSGLSQPRGPQ 157



 Score = 30.0 bits (66), Expect = 3.6
 Identities = 43/128 (33%), Positives = 52/128 (40%), Gaps = 23/128 (17%)

Query: 222 KHTEAAAYLSCQ-LHAARQRLQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGV 280
           +H  A A L  +  HA    ++ AA  R   APA  P  P   R  A A P    RGPG 
Sbjct: 67  QHRRAVARLPAEPAHAVPHPVRPAARLR---APARDP-VPLAGRQRAGAAP----RGPGG 118

Query: 281 GARLAGV-----TRDGRG--GPARDAAR-SPQAGPGSEGSRPSSR-KRGEAAP-----AP 326
            AR   V       DG G   PA   AR S  + P     R + R +RG A P      P
Sbjct: 119 PARTPAVRAGRRAADGPGEEAPAPGRARFSGLSQPRGPQPRAAVRPRRGGALPRGTGAVP 178

Query: 327 PKSPNRQP 334
            + P  +P
Sbjct: 179 ERGPGTEP 186



 Score = 30.0 bits (66), Expect = 3.6
 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 7/68 (10%)

Query: 253 PAASPGAPGPSRPAARAQ------PAQRARGPGVGARLAGVTRDGRGGPARDAARSP-QA 305
           PA  P  P P +  A A+      PA+ AR    GA  A  T   +G     + R+P Q 
Sbjct: 443 PAVLPWVPSPGKGTAHARLHFRXRPAEGARRHRCGAEAAPQTWGVQGQLTPTSTRAPGQG 502

Query: 306 GPGSEGSR 313
           G  S+GSR
Sbjct: 503 GCLSDGSR 510


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 42/172 (24%), Positives = 66/172 (38%), Gaps = 3/172 (1%)

Query: 125  QTVSLQVYTELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQR 184
            + ++ Q   EL   LE           A + L   C  L  Q E  A A AEL+R +++ 
Sbjct: 1354 KALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKA 1413

Query: 185  EALVSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQAA 244
             A V+  R     +  +  EEL     +  +   E ++  EAA      L  A+ RLQ  
Sbjct: 1414 NAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTE 1473

Query: 245  AAQ---RPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRG 293
            +       + A +A+       R   RA   +R +   +   L    R+ RG
Sbjct: 1474 SEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRG 1525



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 25/133 (18%)

Query: 133  TELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALR 192
            ++L+  +E  +    Q +   +EL+++   LE +LEA  AA A + ++ A+    +  L 
Sbjct: 1137 SQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELS 1196

Query: 193  ----------------CSLRTEE----RRFLEELRRRSHRATVLGTELQKHTEAAAYLSC 232
                            C  R  E    RR LEE   R H ATV     +K  E AA L  
Sbjct: 1197 ERLEEAGGASAGQREGCRKREAELGRLRRELEEAALR-HEATVAALR-RKQAEGAAELGE 1254

Query: 233  Q---LHAARQRLQ 242
            Q   L   RQ+L+
Sbjct: 1255 QVDSLQRVRQKLE 1267


>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
          Length = 864

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 39/112 (34%), Positives = 55/112 (49%), Gaps = 10/112 (8%)

Query: 228 AYLSCQLHAARQRLQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARG--PGVGARLA 285
           ++L  Q   A +R   ++    + APA  P  PG   PA    PA  A G  P V +R  
Sbjct: 761 SWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSR-P 819

Query: 286 GVTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVL 337
           G + D  G P +  +R  +A PG     PS  + G+A+P+ P+SP R PF L
Sbjct: 820 GASPDPFGPPPQVPSRPNRAPPGV----PS--RSGQASPSRPESP-RPPFDL 864



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 34/121 (28%), Positives = 41/121 (33%), Gaps = 28/121 (23%)

Query: 241 LQAAAAQRPQPAPAASPGAPGPSRPAAR----AQPAQRARGPGVGARLAGVTRDGRGGPA 296
           +       P P P         S PA R    + P  + R P V              PA
Sbjct: 745 INTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVP-------------PA 791

Query: 297 RDAARSPQAGPGSEGS----RPSSRKRGEAAPAP-------PKSPNRQPFVLPDVSKASS 345
           R  +R P  GP   GS     P    R  A+P P       P  PNR P  +P  S  +S
Sbjct: 792 RPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAPPGVPSRSGQAS 851

Query: 346 P 346
           P
Sbjct: 852 P 852


>gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens]
          Length = 1235

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 58/219 (26%), Positives = 86/219 (39%), Gaps = 33/219 (15%)

Query: 140 EMREAQSHQQEAASRE----LESKCRALESQ-LEARAAANAELRREVAQREALVSALRCS 194
           ++++ Q+ ++    R      E +CR  + + L AR + + +L RE   ++     L C+
Sbjct: 619 QLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQDLLREDLNKKQTQKDLECA 678

Query: 195 LRTEERRFLEELRRRS----HRATVLGTELQKHTEAAAYLSC---------QLHAARQR- 240
           L   +     EL  R      R     T LQ  TE    L           Q HAA+ R 
Sbjct: 679 LLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEYNKRREQELRQKHAAQVRQ 738

Query: 241 ----LQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPA 296
               L+  A QRP   P   PGA GP  P       Q+   PG  A L     D R    
Sbjct: 739 QPKSLKVRAGQRPPGLPLPIPGALGP--PNTGTPIEQQPCSPGQEAVL-----DQRMLGE 791

Query: 297 RDAARSPQAGPGSEGSRPSSRKR---GEAAPAPPKSPNR 332
            + A   +   G EG+    +++   GE + AP  SP +
Sbjct: 792 EEEAVGERRILGKEGATLEPKQQRILGEESGAPSPSPQK 830


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
           sapiens]
          Length = 828

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 12/89 (13%)

Query: 250 QPAPAASPGAPGPSRPAARAQPAQRA----RGPGVGARLAGVTRDGRGGPARDAARSPQA 305
           QP P   PG PG S P  R  P ++     RGP  G    G+    +G P R   +   A
Sbjct: 503 QPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGL----KGEPGRKGEKGEPA 558

Query: 306 GPGSEGSRPSSRKRG----EAAPAPPKSP 330
            PG  G       RG    E  P PP  P
Sbjct: 559 DPGPPGEPGPRGPRGVPGPEGEPGPPGDP 587



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 24/87 (27%), Positives = 34/87 (39%), Gaps = 15/87 (17%)

Query: 251 PAPAASPGAPG-------PSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSP 303
           P  A SPG  G       P RP  R  P +      +GA+ +   +   G P     +  
Sbjct: 357 PGEAGSPGERGDQGGKGDPGRPGRRGPPGE------IGAKGSKGYQGNSGAPGSPGVKGA 410

Query: 304 QAGPGSEGSRPSSRKRGEAAPAPPKSP 330
           + GPG  G +    +RG+  P    SP
Sbjct: 411 KGGPGPRGPKGEPGRRGD--PGTKGSP 435



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 30/101 (29%), Positives = 39/101 (38%), Gaps = 16/101 (15%)

Query: 247 QRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVT--RDGRGGPARDAARSPQ 304
           +R  P    SPG+ GP     +  P     GP     LAG    +  +G       R PQ
Sbjct: 425 RRGDPGTKGSPGSDGPK--GEKGDP-----GPEGPRGLAGEVGNKGAKGDRGLPGPRGPQ 477

Query: 305 AG---PGSEGSR---PSSRKRGEAA-PAPPKSPNRQPFVLP 338
                PG +GSR     +  RG++  P P   P R  F  P
Sbjct: 478 GALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP 518



 Score = 28.9 bits (63), Expect = 8.0
 Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 14/63 (22%)

Query: 251 PAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSE 310
           P    + G PGP  P  + +P +R   PG            +G P  D  +  +  PG E
Sbjct: 405 PGVKGAKGGPGPRGP--KGEPGRRG-DPGT-----------KGSPGSDGPKGEKGDPGPE 450

Query: 311 GSR 313
           G R
Sbjct: 451 GPR 453


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
           sapiens]
          Length = 918

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 12/89 (13%)

Query: 250 QPAPAASPGAPGPSRPAARAQPAQRA----RGPGVGARLAGVTRDGRGGPARDAARSPQA 305
           QP P   PG PG S P  R  P ++     RGP  G    G+    +G P R   +   A
Sbjct: 503 QPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGL----KGEPGRKGEKGEPA 558

Query: 306 GPGSEGSRPSSRKRG----EAAPAPPKSP 330
            PG  G       RG    E  P PP  P
Sbjct: 559 DPGPPGEPGPRGPRGVPGPEGEPGPPGDP 587



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 24/87 (27%), Positives = 34/87 (39%), Gaps = 15/87 (17%)

Query: 251 PAPAASPGAPG-------PSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSP 303
           P  A SPG  G       P RP  R  P +      +GA+ +   +   G P     +  
Sbjct: 357 PGEAGSPGERGDQGGKGDPGRPGRRGPPGE------IGAKGSKGYQGNSGAPGSPGVKGA 410

Query: 304 QAGPGSEGSRPSSRKRGEAAPAPPKSP 330
           + GPG  G +    +RG+  P    SP
Sbjct: 411 KGGPGPRGPKGEPGRRGD--PGTKGSP 435



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 30/101 (29%), Positives = 39/101 (38%), Gaps = 16/101 (15%)

Query: 247 QRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVT--RDGRGGPARDAARSPQ 304
           +R  P    SPG+ GP     +  P     GP     LAG    +  +G       R PQ
Sbjct: 425 RRGDPGTKGSPGSDGPK--GEKGDP-----GPEGPRGLAGEVGNKGAKGDRGLPGPRGPQ 477

Query: 305 AG---PGSEGSR---PSSRKRGEAA-PAPPKSPNRQPFVLP 338
                PG +GSR     +  RG++  P P   P R  F  P
Sbjct: 478 GALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP 518



 Score = 28.9 bits (63), Expect = 8.0
 Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 14/63 (22%)

Query: 251 PAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSE 310
           P    + G PGP  P  + +P +R   PG            +G P  D  +  +  PG E
Sbjct: 405 PGVKGAKGGPGPRGP--KGEPGRRG-DPGT-----------KGSPGSDGPKGEKGDPGPE 450

Query: 311 GSR 313
           G R
Sbjct: 451 GPR 453


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
           sapiens]
          Length = 1019

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 12/89 (13%)

Query: 250 QPAPAASPGAPGPSRPAARAQPAQRA----RGPGVGARLAGVTRDGRGGPARDAARSPQA 305
           QP P   PG PG S P  R  P ++     RGP  G    G+    +G P R   +   A
Sbjct: 503 QPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGL----KGEPGRKGEKGEPA 558

Query: 306 GPGSEGSRPSSRKRG----EAAPAPPKSP 330
            PG  G       RG    E  P PP  P
Sbjct: 559 DPGPPGEPGPRGPRGVPGPEGEPGPPGDP 587



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 24/87 (27%), Positives = 34/87 (39%), Gaps = 15/87 (17%)

Query: 251 PAPAASPGAPG-------PSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSP 303
           P  A SPG  G       P RP  R  P +      +GA+ +   +   G P     +  
Sbjct: 357 PGEAGSPGERGDQGGKGDPGRPGRRGPPGE------IGAKGSKGYQGNSGAPGSPGVKGA 410

Query: 304 QAGPGSEGSRPSSRKRGEAAPAPPKSP 330
           + GPG  G +    +RG+  P    SP
Sbjct: 411 KGGPGPRGPKGEPGRRGD--PGTKGSP 435



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 30/101 (29%), Positives = 39/101 (38%), Gaps = 16/101 (15%)

Query: 247 QRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVT--RDGRGGPARDAARSPQ 304
           +R  P    SPG+ GP     +  P     GP     LAG    +  +G       R PQ
Sbjct: 425 RRGDPGTKGSPGSDGPK--GEKGDP-----GPEGPRGLAGEVGNKGAKGDRGLPGPRGPQ 477

Query: 305 AG---PGSEGSR---PSSRKRGEAA-PAPPKSPNRQPFVLP 338
                PG +GSR     +  RG++  P P   P R  F  P
Sbjct: 478 GALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP 518



 Score = 28.9 bits (63), Expect = 8.0
 Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 14/63 (22%)

Query: 251 PAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSE 310
           P    + G PGP  P  + +P +R   PG            +G P  D  +  +  PG E
Sbjct: 405 PGVKGAKGGPGPRGP--KGEPGRRG-DPGT-----------KGSPGSDGPKGEKGDPGPE 450

Query: 311 GSR 313
           G R
Sbjct: 451 GPR 453


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 31/115 (26%), Positives = 45/115 (39%)

Query: 128  SLQVYTELTHDLEMREAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREAL 187
            S Q   EL H LE      +    A +     C  L  Q E      AEL+R +++  + 
Sbjct: 1311 STQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSE 1370

Query: 188  VSALRCSLRTEERRFLEELRRRSHRATVLGTELQKHTEAAAYLSCQLHAARQRLQ 242
            V+  R    T+  +  EEL     +      E ++H EA       L   +QRLQ
Sbjct: 1371 VAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQ 1425


>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 44/155 (28%), Positives = 61/155 (39%), Gaps = 9/155 (5%)

Query: 156 LESKCRALESQLEARAAANAELRREVAQREALVSALRC--SLRTEERRFLEELRRRSHRA 213
           L S+  +   Q   RA+    +R E   R+ LV +     + R   R     LRRR  R 
Sbjct: 378 LRSRSESPAGQCVLRASQQRGVRLEGGGRQQLVPSQVAWRAARAPGRHQAAVLRRRRARV 437

Query: 214 T----VLGTELQKHTEAAAYLSCQLHAARQRLQAAAAQRPQPAPAASPGAPGPSRPAARA 269
                +    +    +A   L  QLHA   RL +  A+   PAP+A      P+R    A
Sbjct: 438 ARAQQLARLRVGHAVQAPQALQAQLHA---RLPSRRARSSAPAPSAQGRCMTPARSPVAA 494

Query: 270 QPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQ 304
           + A R RG   G   +  TR  +G   R     PQ
Sbjct: 495 REAARLRGARPGPAASAATRMWQGSGRRRPGPDPQ 529



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 74/291 (25%), Positives = 111/291 (38%), Gaps = 41/291 (14%)

Query: 97  LKALLGGGPRDVPPSFPNPRFTPPP---RGHQTVSLQVYTELTHDLEMREAQSHQQEAAS 153
           L  L+  G + +  S   PR +PPP      ++  +          ++R+       AA 
Sbjct: 256 LSLLVSTGTKGLGRSLVTPRPSPPPPLTPQAESGGVDAAPRAPETRQVRKVDGVNPAAAG 315

Query: 154 -RELESKCRALESQLEARAAANAELRREVAQREALVSALRCS----LRTEERRFLEELRR 208
            R   + C  ++S+     A  A L       +   ++  CS    LR   R  L  L  
Sbjct: 316 PRGGATACSGVQSRRPQGLALRATLLPAKRSADMRWNSGSCSHFHILRKVSRPDLSLLH- 374

Query: 209 RSHRATVLGTELQKHTEAAAYLSCQLHAARQ---RLQAAAAQRPQPAPAASPGAPGPSRP 265
                   G  L+  +E+ A   C L A++Q   RL+    Q+  P+  A   A  P R 
Sbjct: 375 --------GLGLRSRSESPAG-QCVLRASQQRGVRLEGGGRQQLVPSQVAWRAARAPGRH 425

Query: 266 AARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPA 325
            A     +RAR     AR   + R   G     A ++PQA      +R  SR+   +APA
Sbjct: 426 QAAVLRRRRAR----VARAQQLARLRVG----HAVQAPQALQAQLHARLPSRRARSSAPA 477

Query: 326 PPKSPNRQPFVLPDVSKASSPLLAREF--LRGAERGHLLYREDSPSRSWPG 374
           P             ++ A SP+ ARE   LRGA  G       + +R W G
Sbjct: 478 PSAQGR-------CMTPARSPVAAREAARLRGARPGP---AASAATRMWQG 518


>gi|239749482 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 195

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 46/120 (38%), Positives = 55/120 (45%), Gaps = 20/120 (16%)

Query: 248 RPQPAPAASPGAPGPSRPAAR------AQPAQRARGP--GVGARLAGVTRDG---RGGPA 296
           RP PA AA P AP     AAR      AQP +R+ GP  G G  +A         RG PA
Sbjct: 49  RPAPA-AAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA 107

Query: 297 RDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGA 356
             AA SP   P    +RPSS       P+ P  P+R P + P    A  P LAR   +G+
Sbjct: 108 VPAAPSPGPLP----ARPSS---PPPRPSLPSGPHR-PVLPPSALAAPRPPLARPLPQGS 159


>gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 44/155 (28%), Positives = 61/155 (39%), Gaps = 9/155 (5%)

Query: 156 LESKCRALESQLEARAAANAELRREVAQREALVSALRC--SLRTEERRFLEELRRRSHRA 213
           L S+  +   Q   RA+    +R E   R+ LV +     + R   R     LRRR  R 
Sbjct: 378 LRSRSESPAGQCVLRASQQRGVRLEGGGRQQLVPSQVAWRAARAPGRHQAAVLRRRRARV 437

Query: 214 T----VLGTELQKHTEAAAYLSCQLHAARQRLQAAAAQRPQPAPAASPGAPGPSRPAARA 269
                +    +    +A   L  QLHA   RL +  A+   PAP+A      P+R    A
Sbjct: 438 ARAQQLARLRVGHAVQAPQALQAQLHA---RLPSRRARSSAPAPSAQGRCMTPARSPVAA 494

Query: 270 QPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQ 304
           + A R RG   G   +  TR  +G   R     PQ
Sbjct: 495 REAARLRGARPGPAASAATRMWQGSGRRRPGPDPQ 529



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 74/291 (25%), Positives = 111/291 (38%), Gaps = 41/291 (14%)

Query: 97  LKALLGGGPRDVPPSFPNPRFTPPP---RGHQTVSLQVYTELTHDLEMREAQSHQQEAAS 153
           L  L+  G + +  S   PR +PPP      ++  +          ++R+       AA 
Sbjct: 256 LSLLVSTGTKGLGRSLVTPRPSPPPPLTPQAESGGVDAAPRAPETRQVRKVDGVNPAAAG 315

Query: 154 -RELESKCRALESQLEARAAANAELRREVAQREALVSALRCS----LRTEERRFLEELRR 208
            R   + C  ++S+     A  A L       +   ++  CS    LR   R  L  L  
Sbjct: 316 PRGGATACSGVQSRRPQGLALRATLLPAKRSADMRWNSGSCSHFHILRKVSRPDLSLLH- 374

Query: 209 RSHRATVLGTELQKHTEAAAYLSCQLHAARQ---RLQAAAAQRPQPAPAASPGAPGPSRP 265
                   G  L+  +E+ A   C L A++Q   RL+    Q+  P+  A   A  P R 
Sbjct: 375 --------GLGLRSRSESPAG-QCVLRASQQRGVRLEGGGRQQLVPSQVAWRAARAPGRH 425

Query: 266 AARAQPAQRARGPGVGARLAGVTRDGRGGPARDAARSPQAGPGSEGSRPSSRKRGEAAPA 325
            A     +RAR     AR   + R   G     A ++PQA      +R  SR+   +APA
Sbjct: 426 QAAVLRRRRAR----VARAQQLARLRVG----HAVQAPQALQAQLHARLPSRRARSSAPA 477

Query: 326 PPKSPNRQPFVLPDVSKASSPLLAREF--LRGAERGHLLYREDSPSRSWPG 374
           P             ++ A SP+ ARE   LRGA  G       + +R W G
Sbjct: 478 PSAQGR-------CMTPARSPVAAREAARLRGARPGP---AASAATRMWQG 518


>gi|239743620 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 285

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 46/120 (38%), Positives = 55/120 (45%), Gaps = 20/120 (16%)

Query: 248 RPQPAPAASPGAPGPSRPAAR------AQPAQRARGP--GVGARLAGVTRDG---RGGPA 296
           RP PA AA P AP     AAR      AQP +R+ GP  G G  +A         RG PA
Sbjct: 49  RPAPA-AAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPA 107

Query: 297 RDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAREFLRGA 356
             AA SP   P    +RPSS       P+ P  P+R P + P    A  P LAR   +G+
Sbjct: 108 VPAAPSPGPLP----ARPSS---PPPRPSLPSGPHR-PVLPPSALAAPRPPLARPLPQGS 159


>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
           sapiens]
          Length = 776

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 13/112 (11%)

Query: 239 QRLQAAAAQRPQPAPAASPGAPGPSRPAARAQPAQRARGPGVGARLAGVTRDGRGGPARD 298
           Q+ QA A + P   P      P P  P + A    + R P  G R        RG P + 
Sbjct: 479 QKGQANATRIPAKTP------PAPKTPPSSATKQVQRRPPPAGPR------SERGEPPKS 526

Query: 299 AARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLAR 350
             RS  + PGS G+ P SR R  + P PP    ++  V+    K+ S   +R
Sbjct: 527 GDRSGYSSPGSPGT-PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSR 577



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 29/116 (25%), Positives = 45/116 (38%), Gaps = 27/116 (23%)

Query: 252 APAASPGAPGPS----------------RPAARAQPAQRARGPGVGARLAGVTRDGRGGP 295
           AP   P A GPS                +PAA  +    +R P + AR+   ++DG G  
Sbjct: 330 APGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSD 389

Query: 296 ARDAARSPQAGPGSEGSRPSSRKRGEAAPAPPKSPNRQPFVLPDVSKASSPLLARE 351
            + A  S ++   +  +RP        +P  P   +  P + P     SSP +  E
Sbjct: 390 DKKAKTSTRSSAKTLKNRPC------LSPKHPTPGSSDPLIQP-----SSPAVCPE 434


>gi|242332545 coiled-coil domain containing 121-like [Homo sapiens]
          Length = 439

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 68/244 (27%), Positives = 96/244 (39%), Gaps = 51/244 (20%)

Query: 142 REAQSHQQEAASRELESKCRALESQLEARAAANAELRREVAQREALVSALRCSLRTEERR 201
           REA+   Q  A R      RAL +  +A  A N  LR+E+     L+   R  L    RR
Sbjct: 192 REARQRVQSLARRAEREAVRALVAHTQAIKADNGRLRQEL-----LLLLRRTQLLHHTRR 246

Query: 202 FLEELRRRSHR--------ATVLG--------------TELQKHTEAAAYLSCQLHAARQ 239
            L E R + HR        A V G                  + T     L+  +  +R 
Sbjct: 247 QLLEQREQLHREHEDTRDLARVHGWLRRGPGGPPLWERPAFSQPTSRPGSLAAPISPSR- 305

Query: 240 RLQAAAAQRPQPAPA-ASPGAPG--PSRPAARAQ----PAQRARGPG-----VGARLAGV 287
               AA+Q P   P+ A+P A    PSR A+R       +  +R P      VG+R+  +
Sbjct: 306 ----AASQTPSVVPSRAAPRASSVVPSREASRVPSLVLSSMDSRVPSLATSKVGSRMPSL 361

Query: 288 TRDGRGGPARDAARSPQAGPGSEGSRP--SSRKRGEAAPAPPK-----SPNRQPFVLPDV 340
           T    G  A    +S +    S GS P  SS+    +  + PK     S +R P +LP  
Sbjct: 362 TASRAGSRALSLVQSLEGSGISSGSSPRVSSQDTLRSTKSGPKLLSGLSRDRDPALLPPQ 421

Query: 341 SKAS 344
           S+ S
Sbjct: 422 SEDS 425


>gi|169167297 PREDICTED: similar to hCG18094 [Homo sapiens]
          Length = 459

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 69/244 (28%), Positives = 98/244 (40%), Gaps = 51/244 (20%)

Query: 128 SLQVYTELTHDLEMREAQSHQQEAASR-ELESKCRALESQ-------------------- 166
           ++Q   E +  L  R AQ+ Q+E   R EL S+ RALE+Q                    
Sbjct: 179 TVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEG 238

Query: 167 ------LEARAAANAE--LRREVAQREALVSALRCSLRTEERRFLEEL---RRRSHRATV 215
                 L  R A   E   R+E  +R+ ++   R   + E +  +E++   R    R+  
Sbjct: 239 EMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQ-ELQNMVEQISLCRAAMGRSAA 297

Query: 216 LGTELQKHTEAAAYLSCQ---LHAARQRLQAAAAQRPQPAPAASPGAPGPSRPAARA--- 269
           L  E +K   AA     Q   +   R+R+   AA+R + A      AP  +RP  R    
Sbjct: 298 LRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSPD 357

Query: 270 ---QPAQRARGPGVG--ARLAGV---TRDGRGGPARDAA-RSPQAGPGSEGSRPSSRKRG 320
              +P +   G G G  AR AG     R  RG   R AA R   AG G  G  P+   R 
Sbjct: 358 WWEEPGRLKAGAGWGWRARRAGTGVPGRGWRGDRVRSAAGRYAAAGAGGGGGVPA---RA 414

Query: 321 EAAP 324
           +A P
Sbjct: 415 DAFP 418


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.130    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,396,188
Number of Sequences: 37866
Number of extensions: 1102603
Number of successful extensions: 17943
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 308
Number of HSP's successfully gapped in prelim test: 1563
Number of HSP's that attempted gapping in prelim test: 11285
Number of HSP's gapped (non-prelim): 6865
length of query: 378
length of database: 18,247,518
effective HSP length: 104
effective length of query: 274
effective length of database: 14,309,454
effective search space: 3920790396
effective search space used: 3920790396
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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