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Search of human proteins with 169202109
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169202109 PREDICTED: hypothetical protein LOC338667 [Homo
sapiens]
(859 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169203683 PREDICTED: hypothetical protein LOC338667 [Homo sap... 1763 0.0
gi|169202109 PREDICTED: hypothetical protein LOC338667 [Homo sap... 1763 0.0
gi|169203189 PREDICTED: hypothetical protein LOC338667 [Homo sap... 1759 0.0
gi|169214048 PREDICTED: hypothetical protein [Homo sapiens] 105 1e-22
gi|89057602 PREDICTED: hypothetical protein [Homo sapiens] 105 2e-22
gi|37551995 PREDICTED: hypothetical protein [Homo sapiens] 105 2e-22
gi|40254891 hypothetical protein FLJ20674 [Homo sapiens] 86 2e-16
gi|109150416 peroxidasin [Homo sapiens] 82 3e-15
gi|118572606 hemicentin 1 [Homo sapiens] 76 2e-13
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 73 1e-12
gi|222352127 sidekick 2 [Homo sapiens] 72 3e-12
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 70 6e-12
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 69 2e-11
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 69 2e-11
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 69 2e-11
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 69 2e-11
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 66 2e-10
gi|119220552 sidekick 1 [Homo sapiens] 63 1e-09
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 62 3e-09
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 61 5e-09
gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] 61 5e-09
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 59 1e-08
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 59 1e-08
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 59 1e-08
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 59 1e-08
gi|126517478 peroxidasin homolog-like [Homo sapiens] 59 1e-08
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 55 4e-07
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens] 54 6e-07
gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens] 54 6e-07
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 53 1e-06
>gi|169203683 PREDICTED: hypothetical protein LOC338667 [Homo
sapiens]
Length = 859
Score = 1763 bits (4565), Expect = 0.0
Identities = 859/859 (100%), Positives = 859/859 (100%)
Query: 1 MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGP 60
MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGP
Sbjct: 1 MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGP 60
Query: 61 APLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHF 120
APLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHF
Sbjct: 61 APLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHF 120
Query: 121 LCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTF 180
LCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTF
Sbjct: 121 LCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTF 180
Query: 181 AWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLAT 240
AWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLAT
Sbjct: 181 AWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLAT 240
Query: 241 RTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDKPVIT 300
RTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDKPVIT
Sbjct: 241 RTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDKPVIT 300
Query: 301 MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGL 360
MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGL
Sbjct: 301 MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGL 360
Query: 361 YTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEG 420
YTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEG
Sbjct: 361 YTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEG 420
Query: 421 PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTAT 480
PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTAT
Sbjct: 421 PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTAT 480
Query: 481 MGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTH 540
MGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTH
Sbjct: 481 MGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTH 540
Query: 541 LLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDP 600
LLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDP
Sbjct: 541 LLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDP 600
Query: 601 GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTI 660
GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTI
Sbjct: 601 GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTI 660
Query: 661 SRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLG 720
SRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLG
Sbjct: 661 SRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLG 720
Query: 721 GLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQ 780
GLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQ
Sbjct: 721 GLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQ 780
Query: 781 YAARHPETFPRSKGTNRGVPEKMLRHRQKTRDSEPPLQETQMRRNGKKANGGPASTRDVA 840
YAARHPETFPRSKGTNRGVPEKMLRHRQKTRDSEPPLQETQMRRNGKKANGGPASTRDVA
Sbjct: 781 YAARHPETFPRSKGTNRGVPEKMLRHRQKTRDSEPPLQETQMRRNGKKANGGPASTRDVA 840
Query: 841 PERRQKIEKLKKILWFSQS 859
PERRQKIEKLKKILWFSQS
Sbjct: 841 PERRQKIEKLKKILWFSQS 859
>gi|169202109 PREDICTED: hypothetical protein LOC338667 [Homo
sapiens]
Length = 859
Score = 1763 bits (4565), Expect = 0.0
Identities = 859/859 (100%), Positives = 859/859 (100%)
Query: 1 MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGP 60
MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGP
Sbjct: 1 MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGP 60
Query: 61 APLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHF 120
APLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHF
Sbjct: 61 APLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHF 120
Query: 121 LCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTF 180
LCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTF
Sbjct: 121 LCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTF 180
Query: 181 AWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLAT 240
AWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLAT
Sbjct: 181 AWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLAT 240
Query: 241 RTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDKPVIT 300
RTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDKPVIT
Sbjct: 241 RTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDKPVIT 300
Query: 301 MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGL 360
MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGL
Sbjct: 301 MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGL 360
Query: 361 YTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEG 420
YTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEG
Sbjct: 361 YTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEG 420
Query: 421 PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTAT 480
PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTAT
Sbjct: 421 PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTAT 480
Query: 481 MGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTH 540
MGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTH
Sbjct: 481 MGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTH 540
Query: 541 LLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDP 600
LLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDP
Sbjct: 541 LLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDP 600
Query: 601 GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTI 660
GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTI
Sbjct: 601 GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTI 660
Query: 661 SRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLG 720
SRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLG
Sbjct: 661 SRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLG 720
Query: 721 GLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQ 780
GLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQ
Sbjct: 721 GLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQ 780
Query: 781 YAARHPETFPRSKGTNRGVPEKMLRHRQKTRDSEPPLQETQMRRNGKKANGGPASTRDVA 840
YAARHPETFPRSKGTNRGVPEKMLRHRQKTRDSEPPLQETQMRRNGKKANGGPASTRDVA
Sbjct: 781 YAARHPETFPRSKGTNRGVPEKMLRHRQKTRDSEPPLQETQMRRNGKKANGGPASTRDVA 840
Query: 841 PERRQKIEKLKKILWFSQS 859
PERRQKIEKLKKILWFSQS
Sbjct: 841 PERRQKIEKLKKILWFSQS 859
>gi|169203189 PREDICTED: hypothetical protein LOC338667 [Homo
sapiens]
Length = 859
Score = 1759 bits (4557), Expect = 0.0
Identities = 858/859 (99%), Positives = 858/859 (99%)
Query: 1 MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGP 60
MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGP
Sbjct: 1 MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGP 60
Query: 61 APLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHF 120
APLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHF
Sbjct: 61 APLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHF 120
Query: 121 LCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTF 180
LCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTF
Sbjct: 121 LCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTF 180
Query: 181 AWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLAT 240
AWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLAT
Sbjct: 181 AWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLAT 240
Query: 241 RTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDKPVIT 300
RTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDKPVIT
Sbjct: 241 RTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDKPVIT 300
Query: 301 MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGL 360
MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGL
Sbjct: 301 MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGL 360
Query: 361 YTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEG 420
YTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPS EAVTLLCAWPGGLPPAQLQWEG
Sbjct: 361 YTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSSEAVTLLCAWPGGLPPAQLQWEG 420
Query: 421 PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTAT 480
PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTAT
Sbjct: 421 PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTAT 480
Query: 481 MGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTH 540
MGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTH
Sbjct: 481 MGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTH 540
Query: 541 LLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDP 600
LLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDP
Sbjct: 541 LLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDP 600
Query: 601 GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTI 660
GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTI
Sbjct: 601 GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTI 660
Query: 661 SRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLG 720
SRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLG
Sbjct: 661 SRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLG 720
Query: 721 GLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQ 780
GLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQ
Sbjct: 721 GLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQ 780
Query: 781 YAARHPETFPRSKGTNRGVPEKMLRHRQKTRDSEPPLQETQMRRNGKKANGGPASTRDVA 840
YAARHPETFPRSKGTNRGVPEKMLRHRQKTRDSEPPLQETQMRRNGKKANGGPASTRDVA
Sbjct: 781 YAARHPETFPRSKGTNRGVPEKMLRHRQKTRDSEPPLQETQMRRNGKKANGGPASTRDVA 840
Query: 841 PERRQKIEKLKKILWFSQS 859
PERRQKIEKLKKILWFSQS
Sbjct: 841 PERRQKIEKLKKILWFSQS 859
>gi|169214048 PREDICTED: hypothetical protein [Homo sapiens]
Length = 881
Score = 105 bits (263), Expect = 1e-22
Identities = 158/677 (23%), Positives = 241/677 (35%), Gaps = 118/677 (17%)
Query: 141 LAVLV--PVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVT 198
LAVLV + P V + NP P P + R + L +G
Sbjct: 199 LAVLVGTTIRLPLVPIPNPGP-----------------PTSLVVWRRGSKVLAAGGLGPG 241
Query: 199 EPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLATRTCYKKKSVSGIRLLDGA 258
PL LDP +R HL + V+ LA+ LD A
Sbjct: 242 APLISLDPAHRDHLRFDQARG---------------VLELASAQ------------LDDA 274
Query: 259 GLRRFKE-RGRMASYLSVFTVAVCGNCELRTVEADGPDKPVITMEPLGLTEEGFWASERE 317
G+ + R ++ FTV V +V+ P+ TEEG
Sbjct: 275 GVYTAEVIRAGVSQQTHEFTVGVYEPLPQLSVQPKAPE-----------TEEG-----AA 318
Query: 318 EVTLSCLAASNPPSHYVWLRDHTQVHT--------------GPTYVIARAGRVHTGLYTC 363
E+ L CL W RD + G +I R R YTC
Sbjct: 319 ELRLRCLGWGPGRGELSWSRDGRALEAAESEGAETPRMRSEGDQLLIVRPVRSDHARYTC 378
Query: 364 LARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEA-----------VTLLCAWPGGLP 412
R+ + + ++++Y P+ P+ V +A VTL CA P
Sbjct: 379 RVRSPF--GHREAAADVSVFYGPD-PPTITVSSDRDAAPARFVTAGSNVTLRCA-AASRP 434
Query: 413 PAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWE---P 469
PA + W P+ A + C +P + L P
Sbjct: 435 PADITWSLADPAEAAVPAGSRLLLPAVGPGHAGTYACLAANPRTGRRRRSLLNLTVADLP 494
Query: 470 LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDL 529
G P C GD+ + C WPGG P A+L + + G SS+ + + A L
Sbjct: 495 PGAPQCSVEGGPGDRSLRFRCSWPGGAPAASLQFQGLPEGIRAGPVSSVLLAAVPAHPRL 554
Query: 530 AGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLL 589
+G TC HL+ T C + EAP+ + P V+ + GEA + G PP++
Sbjct: 555 SGVPITCLARHLVATRT--CTVTPEAPREVLLHPLVAETQLGEAEVALEASGCPPPSRAS 612
Query: 590 WLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEV 649
W + G S L +G +L +G + D G Y + A+G + L
Sbjct: 613 WAREGRPLAPGGGSRLRLSQDGRKLHIGNFSLD--WDLGNYSVLCSGALGAGGDQITL-- 668
Query: 650 LRYPAPPNVTISRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASD 709
P+++ RL R R L W + ++ F +Q A GP G T
Sbjct: 669 ----IGPSISSWRLQ--RARDAAVLTWDVERGALISSFEIQ--AWPDGPALGRTSTYRDW 720
Query: 710 IE-----PESRGR--RLGGLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLG 762
+ P+ R L +PG + FRIL + G PS+ ++ P ++ A+ G
Sbjct: 721 VSLLILGPQERSAVVPLPPRNPGT-WTFRILPILGGQPGTPSQSRVYRAGPTLSHGAIAG 779
Query: 763 -AAGTGMVVATVASLLV 778
G+ + +A +A LL+
Sbjct: 780 IVLGSLLGLALLAVLLL 796
>gi|89057602 PREDICTED: hypothetical protein [Homo sapiens]
Length = 881
Score = 105 bits (261), Expect = 2e-22
Identities = 158/677 (23%), Positives = 240/677 (35%), Gaps = 118/677 (17%)
Query: 141 LAVLV--PVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVT 198
LAVLV + P V + NP P P + R + L +G
Sbjct: 199 LAVLVGTTIRLPLVPIPNPGP-----------------PTSLVVWRRGSKVLAAGGLGPG 241
Query: 199 EPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLATRTCYKKKSVSGIRLLDGA 258
PL LDP +R HL + V+ LA+ LD A
Sbjct: 242 APLISLDPAHRDHLRFDQARG---------------VLELASAQ------------LDDA 274
Query: 259 GLRRFKE-RGRMASYLSVFTVAVCGNCELRTVEADGPDKPVITMEPLGLTEEGFWASERE 317
G+ + R ++ FTV V +V+ P+ TEEG
Sbjct: 275 GVYTAEVIRAGVSQQTHEFTVGVYEPLPQLSVQPKAPE-----------TEEG-----AA 318
Query: 318 EVTLSCLAASNPPSHYVWLRDHTQVHT--------------GPTYVIARAGRVHTGLYTC 363
E+ L CL W RD + G +I R R YTC
Sbjct: 319 ELRLRCLGWGPGRGELSWSRDGRALEAAESEGAETPRMRSEGDQLLIVRPVRSDHARYTC 378
Query: 364 LARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEA-----------VTLLCAWPGGLP 412
R+ + + ++++Y P+ P+ V +A VTL CA P
Sbjct: 379 RVRSPF--GHREAAADVSVFYGPD-PPTITVSSDRDAAPARFVTAGSNVTLRCA-AASRP 434
Query: 413 PAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWE---P 469
PA + W P+ A + C +P + L P
Sbjct: 435 PADITWSLADPAEAAVPAGSRLLLPAVGPGHAGTYACLAANPRTGRRRRSLLNLTVADLP 494
Query: 470 LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDL 529
G P C GD+ + C WPGG P A+L + + G SS+ + + A L
Sbjct: 495 PGAPQCSVEGGPGDRSLRFRCSWPGGAPAASLQFQGLPEGIRAGPVSSVLLAAVPAHPRL 554
Query: 530 AGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLL 589
+G TC HL+ T C + EAP+ + P V+ GEA + G PP++
Sbjct: 555 SGVPITCLARHLVATRT--CTVTPEAPREVLLHPLVAETRLGEAEVALEASGCPPPSRAS 612
Query: 590 WLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEV 649
W + G S L +G +L +G + D G Y + A+G + L
Sbjct: 613 WAREGRPLAPGGGSRLRLSQDGRKLHIGNFSLD--WDLGNYSVLCSGALGAGGDQITL-- 668
Query: 650 LRYPAPPNVTISRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASD 709
P+++ RL R R L W + ++ F +Q A GP G T
Sbjct: 669 ----IGPSISSWRLQ--RARDAAVLTWDVERGALISSFEIQ--AWPDGPALGRTSTYRDW 720
Query: 710 IE-----PESRGR--RLGGLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLG 762
+ P+ R L +PG + FRIL + G PS+ ++ P ++ A+ G
Sbjct: 721 VSLLILGPQERSAVVPLPPRNPGT-WTFRILPILGGQPGTPSQSRVYRAGPTLSHGAIAG 779
Query: 763 -AAGTGMVVATVASLLV 778
G+ + +A +A LL+
Sbjct: 780 IVLGSLLGLALLAVLLL 796
>gi|37551995 PREDICTED: hypothetical protein [Homo sapiens]
Length = 867
Score = 105 bits (261), Expect = 2e-22
Identities = 158/677 (23%), Positives = 240/677 (35%), Gaps = 118/677 (17%)
Query: 141 LAVLV--PVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVT 198
LAVLV + P V + NP P P + R + L +G
Sbjct: 199 LAVLVGTTIRLPLVPIPNPGP-----------------PTSLVVWRRGSKVLAAGGLGPG 241
Query: 199 EPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLATRTCYKKKSVSGIRLLDGA 258
PL LDP +R HL + V+ LA+ LD A
Sbjct: 242 APLISLDPAHRDHLRFDQARG---------------VLELASAQ------------LDDA 274
Query: 259 GLRRFKE-RGRMASYLSVFTVAVCGNCELRTVEADGPDKPVITMEPLGLTEEGFWASERE 317
G+ + R ++ FTV V +V+ P+ TEEG
Sbjct: 275 GVYTAEVIRAGVSQQTHEFTVGVYEPLPQLSVQPKAPE-----------TEEG-----AA 318
Query: 318 EVTLSCLAASNPPSHYVWLRDHTQVHT--------------GPTYVIARAGRVHTGLYTC 363
E+ L CL W RD + G +I R R YTC
Sbjct: 319 ELRLRCLGWGPGRGELSWSRDGRALEAAESEGAETPRMRSEGDQLLIVRPVRSDHARYTC 378
Query: 364 LARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEA-----------VTLLCAWPGGLP 412
R+ + + ++++Y P+ P+ V +A VTL CA P
Sbjct: 379 RVRSPF--GHREAAADVSVFYGPD-PPTITVSSDRDAAPARFVTAGSNVTLRCA-AASRP 434
Query: 413 PAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWE---P 469
PA + W P+ A + C +P + L P
Sbjct: 435 PADITWSLADPAEAAVPAGSRLLLPAVGPGHAGTYACLAANPRTGRRRRSLLNLTVADLP 494
Query: 470 LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDL 529
G P C GD+ + C WPGG P A+L + + G SS+ + + A L
Sbjct: 495 PGAPQCSVEGGPGDRSLRFRCSWPGGAPAASLQFQGLPEGIRAGPVSSVLLAAVPAHPRL 554
Query: 530 AGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLL 589
+G TC HL+ T C + EAP+ + P V+ GEA + G PP++
Sbjct: 555 SGVPITCLARHLVATRT--CTVTPEAPREVLLHPLVAETRLGEAEVALEASGCPPPSRAS 612
Query: 590 WLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEV 649
W + G S L +G +L +G + D G Y + A+G + L
Sbjct: 613 WAREGRPLAPGGGSRLRLSQDGRKLHIGNFSLD--WDLGNYSVLCSGALGAGGDQITL-- 668
Query: 650 LRYPAPPNVTISRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASD 709
P+++ RL R R L W + ++ F +Q A GP G T
Sbjct: 669 ----IGPSISSWRLQ--RARDAAVLTWDVERGALISSFEIQ--AWPDGPALGRTSTYRDW 720
Query: 710 IE-----PESRGR--RLGGLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLG 762
+ P+ R L +PG + FRIL + G PS+ ++ P ++ A+ G
Sbjct: 721 VSLLILGPQERSAVVPLPPRNPGT-WTFRILPILGGQPGTPSQSRVYRAGPTLSHGAIAG 779
Query: 763 -AAGTGMVVATVASLLV 778
G+ + +A +A LL+
Sbjct: 780 IVLGSLLGLALLAVLLL 796
>gi|40254891 hypothetical protein FLJ20674 [Homo sapiens]
Length = 540
Score = 85.5 bits (210), Expect = 2e-16
Identities = 51/189 (26%), Positives = 86/189 (45%), Gaps = 5/189 (2%)
Query: 464 VMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLL 523
++ + P P CW+ G + L+C W GG P W++E + G S + V +L
Sbjct: 219 LVYYPPPSAPQCWAQMASGSFMLQLTCRWDGGYPDPDFLWIEEPGGVIVG-KSKLGVEML 277
Query: 524 QAQEDLAGREFTCRGTHLLRTPD-PHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGG 582
+ G++F C +H++ C +Q+ P L ++EP + GG L C + G
Sbjct: 278 SESQLSDGKKFKCVTSHIVGPESGASCMVQIRGPSL-LSEPMKTCFTGGNVTLTCQVSGA 336
Query: 583 TPPAQLLWLG--PQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGN 640
PPA++LWL Q + + +S ++ +G L I++ G Y C A + VG
Sbjct: 337 YPPAKILWLRNLTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGV 396
Query: 641 SSQSVLLEV 649
+ L V
Sbjct: 397 REMEIWLSV 405
Score = 72.4 bits (176), Expect = 2e-12
Identities = 74/297 (24%), Positives = 112/297 (37%), Gaps = 39/297 (13%)
Query: 291 ADGPDKPVITMEPLGLTEEG-FWASEREEVTLSCLAASNPPSHYVW----LRDHTQVH-- 343
A GP + + + G G +A+ +V SC ++S PP W L ++
Sbjct: 120 ASGPYQIEVHIVATGTLPNGTLYAARGSQVDFSCNSSSRPPPVVEWWFQALNSSSESFGH 179
Query: 344 --TGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEA- 400
T + + G YTCLA N + T +L +YYPP P C + +
Sbjct: 180 NLTVNFFSLLLISPNLQGNYTCLALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMASGSF 239
Query: 401 -VTLLCAWPGGLPPAQLQW-EGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAP 458
+ L C W GG P W E P G + +QL G F C H + P
Sbjct: 240 MLQLTCRWDGGYPDPDFLWIEEPGGVIVGKSKLGVEMLSESQLSDGKKFKCVTSH-IVGP 298
Query: 459 P--ALCTVMLWEP--LGRP--TCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQP-- 510
A C V + P L P TC++ + L+C+ G PPA + WL QP
Sbjct: 299 ESGASCMVQIRGPSLLSEPMKTCFTGGN-----VTLTCQVSGAYPPAKILWLRNLTQPEV 353
Query: 511 -----------LGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAP 556
G +S++ +H +DL + CR + + L ++ P
Sbjct: 354 IIQPSSRHLITQDGQNSTLTIH--NCSQDLDEGYYICRADSPVGVREMEIWLSVKEP 408
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 81.6 bits (200), Expect = 3e-15
Identities = 96/389 (24%), Positives = 161/389 (41%), Gaps = 55/389 (14%)
Query: 295 DKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGP-------- 346
++P IT EP + V +C A NP +WLR++ ++
Sbjct: 244 ERPRITSEPQDAD-----VTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLD 298
Query: 347 --TYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTI-YYPPEGQPSCAVHPSP----- 398
T +I G+Y C+A+N + +TQ ++T+ Y+ +P+ + P
Sbjct: 299 DGTLMIQNTQETDQGIYQCMAKNVAGEVKTQ---EVTLRYFGSPARPTFVIQPQNTEVLV 355
Query: 399 -EAVTLLCAWPGGLPPAQLQW-EGPQGPGPTAPS-NVTWSHA-----AAQLPSGSVFTCT 450
E+VTL C+ G PP ++ W G + P P P N+T S Q SG + C+
Sbjct: 356 GESVTLECSATGH-PPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGE-YACS 413
Query: 451 GQHPALAPPALCTVMLWE-PLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGW------ 503
+ + A +++ P T + Q + CE G PP + W
Sbjct: 414 ATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCE-AKGNPPPVIAWTKGGSQ 472
Query: 504 LDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLE---APQLDV 560
L ++ L SS ++ + + + ++ C+ +++ + HL ++ P
Sbjct: 473 LSVDRRHLVLSSGTLRISGVALHDQ---GQYECQAVNIIGSQKVVAHLTVQPRVTPVFAS 529
Query: 561 AEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYD 620
+V G L CS +G PA + W Q + G F + PEG L I D
Sbjct: 530 IPSDTTVEVGANVQLPCSSQGEPEPA-ITWNKDGVQVTESGK--FHISPEGF---LTIND 583
Query: 621 ADPAHHRGTYQCVARNAVGNSSQSVLLEV 649
PA G Y+CVARN +G++S S++L V
Sbjct: 584 VGPAD-AGRYECVARNTIGSASVSMVLSV 611
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 75.9 bits (185), Expect = 2e-13
Identities = 94/377 (24%), Positives = 150/377 (39%), Gaps = 60/377 (15%)
Query: 319 VTLSCLAASNPPSHYVWLRDHTQVHT-----------GPTYVIARAGRVHTGLYTCLARN 367
VTL+C A PP WL++H ++ G IAR+ +G YTC+A N
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 368 SYLDTRTQTTVQLTIYYPPEGQ----PSCAVHPSPEAVTLLCAWPGGLPPAQLQW--EG- 420
++ + Q L+I PP PS E V L+C G+P +QW +G
Sbjct: 3229 --MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCN-ANGIPTPLIQWLKDGK 3285
Query: 421 PQGPGPT-----APSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPL----G 471
P G T + + T + A +TC +PA + + ++
Sbjct: 3286 PIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGN 3345
Query: 472 RPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSS------SSMAVHLLQA 525
+ T+ D I + C G PP + WL + PL SS + + +++A
Sbjct: 3346 KDEAEKLMTLVDTSINIECR-ATGTPPPQINWL-KNGLPLPLSSHIRLLAAGQVIRIVRA 3403
Query: 526 Q-EDLAGREFTCRGTHLLRTPDPHCHLQLEAP---QLDVAEPRVSVLEGGEAWLECSLRG 581
Q D+A +TC ++ + H +LQ+ AP + ++VL+G + C +
Sbjct: 3404 QVSDVA--VYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMAC-ITD 3460
Query: 582 GTPPAQLLWLGPQQ-----QKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARN 636
GTP + WL Q + T G +L A+ G Y C+A N
Sbjct: 3461 GTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAE----------TEDSGKYTCIASN 3510
Query: 637 AVGNSSQSVLLEVLRYP 653
G S+ +L+VL P
Sbjct: 3511 EAGEVSKHFILKVLEPP 3527
Score = 66.6 bits (161), Expect = 9e-11
Identities = 91/370 (24%), Positives = 142/370 (38%), Gaps = 49/370 (13%)
Query: 321 LSCLAASNPPSHYVWLRDHTQVH---------TGPTYVIARAGRVHTGLYTCLARNSYLD 371
L C +PP +WL+D + G VIA+A +TGLY C+A N+ D
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD 1813
Query: 372 TRTQTTVQLTIYYPPEGQPSC---AVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTA 428
+ + ++T++ PP + S V + V L C G+P + W P TA
Sbjct: 1814 HKKE--FEVTVHVPPTIKSSGLSERVVVKYKPVALQCI-ANGIPNPSITWLKDDQPVNTA 1870
Query: 429 PSNV-------TWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTATM 481
N+ A L +TC + A + + EP P+ M
Sbjct: 1871 QGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP---PSLEDAGKM 1927
Query: 482 GDQFIMLS------CEWPGGEPPATLGWLDEQQQPLGGSSS------SMAVHLLQAQEDL 529
++ +++S C+ G P + W + + L GS+S + + AQ
Sbjct: 1928 LNETVLVSNPVQLECK-AAGNPVPVITWYKDNRL-LSGSTSMTFLNRGQIIDIESAQISD 1985
Query: 530 AGREFTCRGTHLLRTPDPHCHLQLE-APQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQL 588
AG + C + + LQ+ AP + + V+V+ LEC R G P L
Sbjct: 1986 AG-IYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEAR-GIPAPSL 2043
Query: 589 LWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLE 648
WL V ++G + G L L + G Y CVA NA G + + L
Sbjct: 2044 TWL-KDGSPVSSFSNGLQVLSGGRILAL---TSAQISDTGRYTCVAVNAAGEKQRDIDLR 2099
Query: 649 VLRYPAPPNV 658
V PPN+
Sbjct: 2100 VY---VPPNI 2106
Score = 62.0 bits (149), Expect = 2e-09
Identities = 86/387 (22%), Positives = 144/387 (37%), Gaps = 40/387 (10%)
Query: 302 EPLGLTEEGFWASER----EEVTLSCLAASNPPSHYVWLRDH---------TQVHTGPTY 348
EP L + G +E V L C AA NP W +D+ T ++ G
Sbjct: 1917 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQII 1976
Query: 349 VIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWP 408
I A G+Y C+A NS T ++Q+ + G + V L C
Sbjct: 1977 DIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE-A 2035
Query: 409 GGLPPAQLQWEGPQGPGPTAPSNV-------TWSHAAAQLPSGSVFTCTGQHPALAPPAL 461
G+P L W P + + + + +AQ+ +TC + A
Sbjct: 2036 RGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRD 2095
Query: 462 CTVMLWEP---LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDE-----QQQPLGG 513
+ ++ P +G + + + Q + L C+ PP TL WL + ++ L
Sbjct: 2096 IDLRVYVPPNIMGEEQ--NVSVLISQAVELLCQ-SDAIPPPTLTWLKDGHPLLKKPGLSI 2152
Query: 514 SSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAE---PRVSVLEG 570
S + + + AQ GR +TC T++ + + ++ + P +++V+EG
Sbjct: 2153 SENRSVLKIEDAQVQDTGR-YTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEG 2211
Query: 571 GEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTY 630
L C G PP L+W + + G QL++ I + A Y
Sbjct: 2212 NLISLLCE-SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDA---ALY 2267
Query: 631 QCVARNAVGNSSQSVLLEVLRYPAPPN 657
CVA N G + + L+V P N
Sbjct: 2268 SCVASNVAGTAKKEYNLQVYIRPTITN 2294
Score = 57.0 bits (136), Expect = 7e-08
Identities = 88/382 (23%), Positives = 146/382 (38%), Gaps = 61/382 (15%)
Query: 317 EEVTLSCLAASNPPSHYVWLRDHTQVHTGPT---YVIARAGRVH--------TGLYTCLA 365
E V L C A P WL+D + +G T V A ++ TG YTC+A
Sbjct: 3262 ENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 366 RNSYLDTRTQTTVQLTIYYPP-----EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEG 420
N L +Y P + + + ++ + C G PP Q+ W
Sbjct: 3322 TNP--AGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECR-ATGTPPPQINWLK 3378
Query: 421 PQGPGPTAPSNVTWSHAA-------AQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRP 473
P P + S++ A AQ+ +V+TC + A + ++ P
Sbjct: 3379 NGLPLPLS-SHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMD 3437
Query: 474 TCWST---ATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLG------GSSSSMAVHLLQ 524
T + ++C G P ++ WL QPLG S+ M + LL+
Sbjct: 3438 NSMGTEEITVLKGSSTSMAC-ITDGTPAPSMAWL-RDGQPLGLDAHLTVSTHGMVLQLLK 3495
Query: 525 AQEDLAGREFTCRGTHLLRTPDPHCHLQ-LEAPQLDVAE--PRVSVLEGGEAWLECSLRG 581
A+ + +G+ +TC ++ H L+ LE P ++ +E +SV+ L C +
Sbjct: 3496 AETEDSGK-YTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTC-IAS 3553
Query: 582 GTPPAQLLWLG-----PQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARN 636
G P ++ W+ PQ +V G +L AQ+ G Y C+A +
Sbjct: 3554 GIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQV----------EDTGRYTCLASS 3603
Query: 637 AVGNSSQSVLLEVLRYPAPPNV 658
G+ + L +R PPN+
Sbjct: 3604 PAGDDDKEYL---VRVHVPPNI 3622
Score = 56.2 bits (134), Expect = 1e-07
Identities = 99/412 (24%), Positives = 156/412 (37%), Gaps = 61/412 (14%)
Query: 287 RTVEADGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQV-HTG 345
RTV+ P I EP F ++ ++C A+ P W ++ ++ G
Sbjct: 3887 RTVDLTVQVPPSIADEPTD-----FLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRG 3941
Query: 346 PTYVIARAGRV--------HTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCA-VHP 396
Y I +G + H G YTC+ARN+ T L ++ PP QP + +H
Sbjct: 3942 DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVT--LHVHEPPVIQPQPSELHV 3999
Query: 397 SPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSV---------- 446
LL G P + W+ T+ N HA LPSG +
Sbjct: 4000 ILNNPILLPCEATGTPSPFITWQKEGINVNTSGRN----HAV--LPSGGLQISRAVREDA 4053
Query: 447 --FTCTGQHPALAPPALCTVML---WEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATL 501
+ C Q+PA AL + L P+ P D+ I LSCE G PP +
Sbjct: 4054 GTYMCVAQNPA--GTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCE-ADGLPPPDI 4110
Query: 502 GWLDEQQQPLGG------SSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEA 555
W + + + SS S+ + +Q + AG +TC ++ + L +
Sbjct: 4111 TWHKDGRAIVESIRQRVLSSGSLQIAFVQPGD--AGH-YTCMAANVAGSSSTSTKLTVHV 4167
Query: 556 P-QLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQL 614
P ++ E +V E +A L C + G P + W + + P G +
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILPC-VADGIPTPAINWKKDNVLLANL-LGKYTAEPYGELI 4225
Query: 615 RLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPA----PPNVTISR 662
+ D G Y CVA NA G + +V L V P P +V++++
Sbjct: 4226 LENVVLEDS----GFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Score = 55.8 bits (133), Expect = 2e-07
Identities = 90/405 (22%), Positives = 147/405 (36%), Gaps = 51/405 (12%)
Query: 289 VEADGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLR----------- 337
+ D PV EP ++ E VTL C P W R
Sbjct: 785 ITLDVGSPPVFIQEPADVSME-----IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPF 839
Query: 338 ---DHTQVHTGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLT-IYYPPEG-QPSC 392
+Q+ TG +++ G Y C A N + +++TTV +T + P G PS
Sbjct: 840 SVSSISQLRTGALFIL-NLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSV 898
Query: 393 AVHPSPEAVTLLCAWPGGLPPAQLQWEGP-----QGPGPTAPSNVTWSHAAAQLPSGSVF 447
A + +TL C G P + +W Q P T S+ + QL G +
Sbjct: 899 ANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEY 958
Query: 448 TCTGQHPALAPPALCTVMLWE-PLGRPTCWSTATMGDQFIMLSCEWPGGEPPATL----G 502
TC + A +V++ P + +T+ + L C+ G P+ + G
Sbjct: 959 TCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKG 1018
Query: 503 WLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAE 562
L + + +++++ + +G E+ C T+ L + +
Sbjct: 1019 ELISTSSAKFSAGADGSLYVVSPGGEESG-EYVCTATNTAGYAKRKVQLTVYVRPRVFGD 1077
Query: 563 PR---------VSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQ 613
R +SVL G E L C ++ PP + W + Q + P + P G+
Sbjct: 1078 QRGLSQDKPVEISVLAGEEVTLPCEVKS-LPPPIITW-AKETQLISPFSPRHTFLPSGSM 1135
Query: 614 LRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNV 658
+D G Y CVA N GN +Q+V L V PP +
Sbjct: 1136 KITETRTSDS----GMYLCVATNIAGNVTQAVKLNV---HVPPKI 1173
Score = 55.5 bits (132), Expect = 2e-07
Identities = 90/365 (24%), Positives = 142/365 (38%), Gaps = 43/365 (11%)
Query: 318 EVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV---------HTGLYTCLARNS 368
+VTL C + + PP WLR+ ++ P I GR T YTC+A N
Sbjct: 3638 QVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN- 3696
Query: 369 YLDTRTQTTVQLTIYYPP--EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQW--EGPQGP 424
+ +T LT+ PP +G P V ++ L C G+P ++ W +G
Sbjct: 3697 -IAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECI-AEGVPTPRITWRKDGAVLA 3754
Query: 425 GPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCT-------VMLWEPLGRPTCWS 477
G A ++ + + S V T TG++ +A A T + P P +
Sbjct: 3755 GNHARYSIL-ENGFLHIQSAHV-TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTN 3812
Query: 478 TATMGDQFIMLSCEWPGGEPPATLGW--------LDEQQQPLGGSSSSMAVHLLQAQEDL 529
+ + L+CE G P ++ W +D+ Q SS V + + +D
Sbjct: 3813 MTVIVNVQTTLACE-ATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871
Query: 530 AGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-VSVLEGGEAWLECSLRGGTPPAQL 588
A + C T+ L ++ P EP V + A + C+ G P +
Sbjct: 3872 A--TYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCT-ASGVPFPSI 3928
Query: 589 LWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLE 648
W ++ P G+ + GA L A +H G Y CVARNA G++ + V L
Sbjct: 3929 HWT-KNGIRLLPRGDGYRILSSGAIEIL----ATQLNHAGRYTCVARNAAGSAHRHVTLH 3983
Query: 649 VLRYP 653
V P
Sbjct: 3984 VHEPP 3988
Score = 52.4 bits (124), Expect = 2e-06
Identities = 159/714 (22%), Positives = 240/714 (33%), Gaps = 144/714 (20%)
Query: 39 EEVVSVQGVRGGSVELAC-GSGPAPLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASAL 97
+E+ + + G + L C SG P ++W GS V +TD +M +V ++
Sbjct: 2201 DELTQLTVIEGNLISLLCESSGIPPPNLIWK--KKGSPV-----LTD-SMGRVRILSGG- 2251
Query: 98 GVVSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNP 157
R + + E + A + C +VAG A L V + +P + S
Sbjct: 2252 -----RQLQISIAEKSDAAL--YSCVASNVAG----TAKKEYNLQVYI---RPTITNSGS 2297
Query: 158 SPVE-----GASVVATCAVREGTEPVTFAWQ---HRAPRGLGEALVGVTEPLFQLDPVNR 209
P E G S+ C V +G P T W H + G ++ + QL ++
Sbjct: 2298 HPTEIIVTRGKSISLECEV-QGIPPPTVTWMKDGHPLIKAKGVEILDEGH-ILQLKNIHV 2355
Query: 210 THLGWYMCSASNSV-------------------NRLSSDGAFLDVIYLATRTCYKKKSVS 250
+ G Y+C A N N S + + + TC S
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC----EAS 2411
Query: 251 GIRL------LDG-----AGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDKPVI 299
GI L DG + R GRM + T+ G A G ++ +
Sbjct: 2412 GIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT-TMEDAGQYTCVVRNAAGEERKIF 2470
Query: 300 TMEPL-------GLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIAR 352
+ L T E E++ VTL+C NP W +D + + I
Sbjct: 2471 GLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIIS 2530
Query: 353 AGRV---------HTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTL 403
GR HTG YTCLA S + L ++ P +PE VT+
Sbjct: 2531 GGRFLQITNVQVPHTGRYTCLA--SSPAGHKSRSFSLNVFVSPT-IAGVGSDGNPEDVTV 2587
Query: 404 LCAWPGGL-------PPAQLQWEGPQGPGPT------APSNVTWSHAAAQLPSGSVFTCT 450
+ P L PPA + W P + P T AQ + ++C
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCV 2647
Query: 451 GQHPA-----------LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPA 499
+ A PP + LW P P + + L CE P A
Sbjct: 2648 ATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPK--EVKIKVNNTLTLECE-AYAIPSA 2704
Query: 500 TLGWLDEQQQPLGGSSSSMAV--HLLQ---AQEDLAGREFTCRGTHLLRTPDPHCHLQLE 554
+L W + Q ++A H LQ AQ GR +TC +++ + + ++
Sbjct: 2705 SLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGR-YTCVASNIAGEDELDFDVNIQ 2763
Query: 555 AP-----------QLDVAE--PRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPG 601
P LD V+ L C PP L W + P
Sbjct: 2764 VPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPT-LTW----YKDGHPL 2818
Query: 602 TSG--FMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYP 653
TS ++ P G L++ + A G Y CVA N G S + VL P
Sbjct: 2819 TSSDKVLILPGGRVLQIPRAKVEDA---GRYTCVAVNEAGEDSLQYDVRVLVPP 2869
Score = 51.2 bits (121), Expect = 4e-06
Identities = 88/379 (23%), Positives = 139/379 (36%), Gaps = 54/379 (14%)
Query: 317 EEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV---------HTGLYTCLARN 367
+ V L C + + PP WL+D + P I+ V TG YTC A N
Sbjct: 2119 QAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN 2178
Query: 368 SYLDTRTQTTVQLTIYYPPEGQPSCAVHP----SPEAVTLLCAWPGGLPPAQLQWEGPQG 423
+ +T+ + I+ PP S + ++LLC G+PP L W+
Sbjct: 2179 --VAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCE-SSGIPPPNLIWKKKGS 2235
Query: 424 PGPT--------APSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTC 475
P T + A+ ++++C + A + ++ RPT
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYI---RPTI 2292
Query: 476 WSTATMGDQFIM-------LSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAV--HLLQAQ 526
++ + + I+ L CE G PP T+ W+ + + + H+LQ +
Sbjct: 2293 TNSGSHPTEIIVTRGKSISLECEVQG-IPPPTVTWMKDGHPLIKAKGVEILDEGHILQLK 2351
Query: 527 E---DLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR----VSVLEGGEAWLECSL 579
GR + C ++ D L + AP + R +SV+E L C
Sbjct: 2352 NIHVSDTGR-YVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEA 2410
Query: 580 RGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVG 639
G P + W V S +L G LRL + A G Y CV RNA G
Sbjct: 2411 -SGIPLPSITWF-KDGWPVSLSNSVRILSG-GRMLRLMQTTMEDA---GQYTCVVRNAAG 2464
Query: 640 NSSQSVLLEVLRYPAPPNV 658
+ L VL PP++
Sbjct: 2465 EERKIFGLSVL---VPPHI 2480
Score = 50.8 bits (120), Expect = 5e-06
Identities = 106/460 (23%), Positives = 165/460 (35%), Gaps = 84/460 (18%)
Query: 300 TMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHT----------GPTYV 349
T++ GL+E + + V L C+A P WL+D V+T G
Sbjct: 1827 TIKSSGLSERV--VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQ 1884
Query: 350 IARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPG 409
IA+ G YTC+A N+ TQ +QL ++ PP + + + V+
Sbjct: 1885 IAKTLLEDAGRYTCVATNA--AGETQQHIQLHVHEPPSLEDAGKMLNETVLVS------- 1935
Query: 410 GLPPAQLQWEGPQGPGPTAPSNVTW----------------------SHAAAQLPSGSVF 447
P QL+ + P P +TW +AQ+ ++
Sbjct: 1936 --NPVQLECKAAGNPVPV----ITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIY 1989
Query: 448 TCTGQHPALAPPALCTVMLW-EPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDE 506
C + A A ++ + P + A + + + L CE G P +L WL +
Sbjct: 1990 KCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE-ARGIPAPSLTWL-K 2047
Query: 507 QQQPLGGSSSSMAV-------HLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEA-PQL 558
P+ S+ + V L AQ GR +TC + L++ P +
Sbjct: 2048 DGSPVSSFSNGLQVLSGGRILALTSAQISDTGR-YTCVAVNAAGEKQRDIDLRVYVPPNI 2106
Query: 559 DVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKV-DPGTSGFMLHPEGAQLRLG 617
E VSVL L C PP L WL + PG S E + L
Sbjct: 2107 MGEEQNVSVLISQAVELLCQ-SDAIPPPTLTWLKDGHPLLKKPGLS----ISENRSV-LK 2160
Query: 618 IYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQLQWA 677
I DA G Y C A N G + ++ + + PPN+ S +L
Sbjct: 2161 IEDAQ-VQDTGRYTCEATNVAGKTEKNYNVNIW---VPPNIGGSD----------ELTQL 2206
Query: 678 ILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGR 717
+ GNL L + +S + P W+ S + +S GR
Sbjct: 2207 TVIEGNLISLLCE--SSGIPPPNLIWKKKGSPVLTDSMGR 2244
Score = 48.5 bits (114), Expect = 3e-05
Identities = 95/390 (24%), Positives = 140/390 (35%), Gaps = 68/390 (17%)
Query: 320 TLSCLAASNPPSHYVWLRDHTQVHT---------GPTYVIARAGRVHTGLYTCLARNSYL 370
+L C A S PP+ W +D T + + G T I A + G Y+C+A N
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 371 DTRTQTTVQLTIYYPPEGQPSCAVHP--SPEAV--------TLLCAWPGGLPPAQLQWEG 420
+ V+ +Y PP P SP+ V TL C +P A L W
Sbjct: 2654 EMIKHYEVK--VYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECE-AYAIPSASLSWYK 2710
Query: 421 PQGPGPT------APSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPT 474
P + A + T AQ+ +TC + A V + P
Sbjct: 2711 DGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQK 2770
Query: 475 CWSTATMGDQF-------------IMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSM--- 518
W M D I L CE PP TL W + PL S +
Sbjct: 2771 LWEIGNMLDTGRNGEAKDVIINNPISLYCE-TNAAPPPTLTWYKDGH-PLTSSDKVLILP 2828
Query: 519 ---AVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQL------DVAEPRVSVLE 569
+ + +A+ + AGR +TC + +++ P + D+ E V+VL
Sbjct: 2829 GGRVLQIPRAKVEDAGR-YTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPE-EVTVLV 2886
Query: 570 GGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQ-LRLGIYDADPAHHRG 628
A +EC L G+P + W Q ++ F+ + Q L I D G
Sbjct: 2887 NKSALIEC-LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDI------G 2939
Query: 629 TYQCVARNAVGNSSQSVLLEVLRYPAPPNV 658
Y CVA N G++ + L V PP+V
Sbjct: 2940 RYVCVAENTAGSAKKYFNLNV---HVPPSV 2966
Score = 45.8 bits (107), Expect = 2e-04
Identities = 86/393 (21%), Positives = 142/393 (36%), Gaps = 59/393 (15%)
Query: 295 DKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHT--------QVHTGP 346
+ P +T+ P + G EV++ C A P W + ++ +
Sbjct: 610 EPPKVTVMPKNQSFTG-----GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG 664
Query: 347 TYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCA 406
T I A G+Y CLA NS + +T++ I P + + +T++
Sbjct: 665 TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRY-IEAPKLMVVQSELLVALGDITVMEC 723
Query: 407 WPGGLPPAQLQWEGPQGPGPTAPSN---------VTWSHAAAQLPSGSVFTCTGQHPALA 457
G+PP Q++W +G PS + L +G +TC + A
Sbjct: 724 KTSGIPPPQVKWF--KGDLELRPSTFLIIDPLLGLLKIQETQDLDAGD-YTCVAINEAGR 780
Query: 458 PPALCTVMLWEP---LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGS 514
T+ + P + P S + + L C + G P T+ W P+
Sbjct: 781 ATGKITLDVGSPPVFIQEPADVSMEIGSN--VTLPC-YVQGYPEPTIKWRRLDNMPIFSR 837
Query: 515 --SSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLE---------APQLDVAEP 563
S S L + + +GT++ + +Q E AP + ++
Sbjct: 838 PFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPS 897
Query: 564 RVSVLEGGEAWLECSLRGGTPPAQLLWLGPQ----QQKVDPGTSGFMLHPEGAQLRLGIY 619
+V+EG + L C+L G P + W+ Q S LH E QL+ G
Sbjct: 898 VANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDG-- 955
Query: 620 DADPAHHRGTYQCVARNAVG--NSSQSVLLEVL 650
G Y CVA N G N + SV++ VL
Sbjct: 956 --------GEYTCVASNVAGTNNKTTSVVVHVL 980
Score = 45.8 bits (107), Expect = 2e-04
Identities = 84/376 (22%), Positives = 136/376 (36%), Gaps = 50/376 (13%)
Query: 317 EEVTLSCLAASNPPSHYVWLRD----------HTQVHTGPTYVIARAGRVHTGLYTCLAR 366
EEVTL C S PP W ++ HT + +G + I +G+Y C+A
Sbjct: 1095 EEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG-SMKITETRTSDSGMYLCVAT 1153
Query: 367 NSYLDTRTQTTVQLTIYYPPEGQ--PSCAVHPSPEAVTLLCAWPGGLPPAQLQWEG---- 420
N + V+L ++ PP+ Q P + V + C G P + W
Sbjct: 1154 N--IAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCN-AQGTPLPVITWSKGGST 1210
Query: 421 --PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWS- 477
G + + T S A ++TC + A T+ + EP PT
Sbjct: 1211 MLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEP---PTVEDL 1267
Query: 478 ----TATMGDQFIMLSCEWP---GGEPPATLGWLDEQQQPLGGSSSSMAVH-----LLQA 525
T ++ E+P G P T+ WL ++ G + ++ +
Sbjct: 1268 EPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIAS 1327
Query: 526 QEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR---VSVLEGGEAWLECSLRGG 582
E+ C + T + +L++ P + + + VSVL L C + G
Sbjct: 1328 VTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVE-G 1386
Query: 583 TPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSS 642
TP ++W Q + T G L+L + A P G Y C A N G S
Sbjct: 1387 TPSPIIMWYKDNVQVTESST--IQTVNNGKILKL--FRATP-EDAGRYSCKAINIAGTSQ 1441
Query: 643 QSVLLEVLRYPAPPNV 658
+ ++VL PP +
Sbjct: 1442 KYFNIDVL---VPPTI 1454
Score = 45.8 bits (107), Expect = 2e-04
Identities = 82/380 (21%), Positives = 139/380 (36%), Gaps = 61/380 (16%)
Query: 319 VTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV---------HTGLYTCLARNSY 369
++L C + PP W +D + + +I GRV G YTC+A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 370 LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLC-------AWPGGLPPAQLQWEGPQ 422
+ Q V++ + +G S PE VT+L G P + W+
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANS----DLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDG 2910
Query: 423 GPGPTAPSNVTWSHAA------AQLPSGSVFTCTGQHPALAPPALCTVMLWEPLG--RPT 474
P + S+ Q+ + C ++ A + + + P P
Sbjct: 2911 QPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK 2970
Query: 475 CWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAV------HLLQAQED 528
+ + + FI L+CE G PP L WL + +QP+ +++++ V +++A+
Sbjct: 2971 SENLTVVVNNFISLTCEVS-GFPPPDLSWL-KNEQPIKLNTNTLIVPGGRTLQIIRAKVS 3028
Query: 529 LAGREFTCRGTHLLRTPDPHCHLQLEAPQL-----DVAEPRVSVLEGGEAWLECSLRGGT 583
G E+TC + L + P + V+V EG LEC
Sbjct: 3029 -DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECE-SNAV 3086
Query: 584 PPAQLLW-----LGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAV 638
PP + W + + V+ G MLH + A++ G Y C A N
Sbjct: 3087 PPPVITWYKNGRMITESTHVEILADGQMLHIKKAEV----------SDTGQYVCRAINVA 3136
Query: 639 GNSSQSVLLEVLRYPAPPNV 658
G ++ L V PP++
Sbjct: 3137 GRDDKNFHLNVY---VPPSI 3153
Score = 42.7 bits (99), Expect = 0.001
Identities = 81/376 (21%), Positives = 130/376 (34%), Gaps = 49/376 (13%)
Query: 320 TLSCLAASNPPSHYVWLRD--------HTQVHT-GPTYVIARAGRVHTGLYTCLARNSYL 370
+++C+ P WLRD H V T G + +A +G YTC+A N
Sbjct: 3454 SMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAG 3513
Query: 371 DTRTQTTVQLTIYYPP------EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGP 424
+ L + PP E + + +P +T + + G+P ++ W P
Sbjct: 3514 EVSKHFI--LKVLEPPHINGSEEHEEISVIVNNPLELTCIAS---GIPAPKMTWMKDGRP 3568
Query: 425 GPTAPSNVTWSH------AAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP---LGRPTC 475
P T + AQ+ +TC PA V + P G
Sbjct: 3569 LPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP 3628
Query: 476 WSTATMGDQFIMLSCEWPGGEPPATLGWL--DEQQQPLGGSSSSMAVHLLQAQEDLAG-- 531
+ ++ + L C+ PP + WL E+ Q LQ G
Sbjct: 3629 RDITVLRNRQVTLECK-SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDT 3687
Query: 532 REFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-VSVLEGGEAWLECSLRGGTPPAQLLW 590
+TC +++ L + P P+ + +L LEC + G P ++ W
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLEC-IAEGVPTPRITW 3746
Query: 591 LGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAH--HRGTYQCVARNAVGNSSQSVLLE 648
+ V G H + L G AH G Y C+A NA G + + L+
Sbjct: 3747 R--KDGAVLAGN-----HARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQ 3799
Query: 649 V----LRYPAPPNVTI 660
V P P N+T+
Sbjct: 3800 VHVPPSIAPGPTNMTV 3815
Score = 42.4 bits (98), Expect = 0.002
Identities = 77/386 (19%), Positives = 142/386 (36%), Gaps = 55/386 (14%)
Query: 317 EEVTLSCLAASNPPSHYVWLR---------DHTQVHTGPTYVIARAGRVHTGLYTCLARN 367
+ V + C A P W + +H + T I +A G+YTC+A N
Sbjct: 1186 QRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN 1245
Query: 368 SYLDTRTQTTVQLTIYYPP---EGQPSCAVHPSPEAVTLLCAWP---GGLPPAQLQW--E 419
+ +T + L + PP + +P +P G P ++W
Sbjct: 1246 --IAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHN 1303
Query: 420 GPQ----GPGPTAPSNVTWSHAAAQLP-SGSVFTCTGQHPALAPPALCTVMLWEP---LG 471
G + PG + + T A+ P + C + A + + P
Sbjct: 1304 GRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363
Query: 472 RPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGS----SSSMAVHLLQAQE 527
+ + + + +Q L CE G P + + D Q + ++ + L +A
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP 1423
Query: 528 DLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEP---RVSVLEGGEAWLECSLRGGTP 584
+ AGR ++C+ ++ T + ++ + P + VSV+ + LEC ++G TP
Sbjct: 1424 EDAGR-YSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKG-TP 1481
Query: 585 PAQLLWL--GPQQQKVDPGTS----GFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAV 638
+ W G DP G +LH + A+ + +G YQC NA
Sbjct: 1482 FPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNAR----------RNDKGRYQCTVSNAA 1531
Query: 639 GNSSQSVLLEVLRYPAPPNVTISRLT 664
G ++ + L + PP++ +T
Sbjct: 1532 GKQAKDIKLTIY---IPPSIKGGNVT 1554
Score = 37.7 bits (86), Expect = 0.046
Identities = 118/572 (20%), Positives = 188/572 (32%), Gaps = 113/572 (19%)
Query: 118 GHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNP-SPVEGASVVATCAVREGTE 176
G + C+ +++AG + + + VLVP + N S V V C V+
Sbjct: 1427 GRYSCKAINIAG----TSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPF 1482
Query: 177 PVTFAWQHRAPRGLGEALVGVTE--PLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLD 234
P ++ P LG+ V + + + L R G Y C+ SN+ + + D
Sbjct: 1483 PDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKD----- 1537
Query: 235 VIYLATRTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCG-NCELRTVEADG 293
T Y S+ G G + + +SV ++ CE R G
Sbjct: 1538 ----IKLTIYIPPSIKG---------------GNVTTDISVLINSLIKLECETR-----G 1573
Query: 294 PDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARA 353
P IT W + + + S A + G I RA
Sbjct: 1574 LPMPAIT-----------WYKDGQPIMSSSQA--------------LYIDKGQYLHIPRA 1608
Query: 354 GRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAV-----TLLCAWP 408
+ YTC N + + + + +Y PP + + A + + V TL C
Sbjct: 1609 QVSDSATYTCHVAN--VAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECK-A 1665
Query: 409 GGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSV-------FTCTGQHPA------ 455
G P L W G A N+ +L S + C A
Sbjct: 1666 AGNPSPILTWL-KDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIK 1724
Query: 456 -----LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQP 510
L PPA+ G M + + L C G PP T+ WL + Q
Sbjct: 1725 YEVDVLVPPAI--------EGGDETSYFIVMVNNLLELDCH-VTGSPPPTIMWLKDGQLI 1775
Query: 511 LGGSSSSMAVH-----LLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAP---QLDVAE 562
+ ++ + QAQ G + C + + + P +
Sbjct: 1776 DERDGFKILLNGRKLVIAQAQVSNTGL-YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLS 1834
Query: 563 PRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDAD 622
RV V++ L+C + G P + WL Q V+ + G L++ +
Sbjct: 1835 ERV-VVKYKPVALQC-IANGIPNPSITWL-KDDQPVNTAQGNLKIQSSGRVLQIAKTLLE 1891
Query: 623 PAHHRGTYQCVARNAVGNSSQSVLLEVLRYPA 654
A G Y CVA NA G + Q + L V P+
Sbjct: 1892 DA---GRYTCVATNAAGETQQHIQLHVHEPPS 1920
Score = 35.4 bits (80), Expect = 0.23
Identities = 79/374 (21%), Positives = 129/374 (34%), Gaps = 53/374 (14%)
Query: 317 EEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHT----------------GL 360
E L+CL S + W R+ V +A R+ T G
Sbjct: 535 ERAVLTCLIISAVDYNLTWQRNDRDVR------LAEPARIRTLANLSLELKSVKFNDAGE 588
Query: 361 YTCLARNSYLDTRTQTTVQLTIYYPPEG--QPSCAVHPSPEAVTLLCAWPGGLPPAQLQW 418
Y C+ + + +V LT+ PP+ P V+++C+ G P ++ W
Sbjct: 589 YHCMVSSE--GGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCS-ATGYPKPKIAW 645
Query: 419 E-------GPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLG 471
G T+ + +AA + ++ C + A T+ E
Sbjct: 646 TVNDMFIVGSHRYRMTSDGTLFIKNAAPK--DAGIYGCLASNSAGTDKQNSTLRYIEAPK 703
Query: 472 RPTCWST--ATMGDQFIMLSCEWPGGEPPATLGWL--DEQQQPLGGSSSSMAVHLLQAQE 527
S +GD +M C+ G PP + W D + +P + LL+ QE
Sbjct: 704 LMVVQSELLVALGDITVM-ECK-TSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQE 761
Query: 528 --DLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-VSVLEGGEAWLECSLRGGTP 584
DL ++TC + L + +P + + EP VS+ G L C ++G
Sbjct: 762 TQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPE 821
Query: 585 PAQLLWLGPQQQKVDP---GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNS 641
P + W + S GA L ++ +D +GTY C A N G
Sbjct: 822 PT-IKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD----KGTYICEAENQFGKI 876
Query: 642 SQSVLLEVLRYPAP 655
+ V AP
Sbjct: 877 QSETTVTVTGLVAP 890
Score = 32.3 bits (72), Expect = 1.9
Identities = 66/304 (21%), Positives = 110/304 (36%), Gaps = 70/304 (23%)
Query: 317 EEVTLSCLAASNP-------------PSHYVWLRDHTQVHTGPTYVIARAGRVHTGLYTC 363
E++ LSC A P P+H+ + H+++ VI R + +G Y C
Sbjct: 4275 EQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSEL------VIERVSKEDSGTYVC 4328
Query: 364 LARNSYLDTRTQTTVQLTIYYPP---EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEG 420
A NS + V + PP PS + P L C G P +QW
Sbjct: 4329 TAENSVGFVKAIGFVY--VKEPPVFKGDYPSNWIEPLGGNAILNCEVKGD-PTPTIQWN- 4384
Query: 421 PQGPGPTAPSNVTWSHAAAQLPSGSV------------FTCTGQHPA-LAPPALCTVMLW 467
++ SH QL +GS+ +TC + A + ++ +
Sbjct: 4385 ------RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Query: 468 EPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSS-----SSMAVHL 522
P+ T I+L+C+ GEP T+ W Q + S+ ++++
Sbjct: 4439 PPIITLEPVETVINAGGKIILNCQ-ATGEPQPTITW-SRQGHSISWDDRVNVLSNNSLYI 4496
Query: 523 LQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGG----EAWLECS 578
AQ++ EF C +L+ + + V P + + GG AW CS
Sbjct: 4497 ADAQKEDTS-EFECVARNLMGS-------------VLVRVPVIVQVHGGFSQWSAWRACS 4542
Query: 579 LRGG 582
+ G
Sbjct: 4543 VTCG 4546
>gi|81158224 neuronal cell adhesion molecule isoform B precursor
[Homo sapiens]
Length = 1183
Score = 72.8 bits (177), Expect = 1e-12
Identities = 113/482 (23%), Positives = 191/482 (39%), Gaps = 64/482 (13%)
Query: 303 PLGLTEEGFWASEREEV-----TLSCLAASNPPSHYVWLRDHTQVHTGPTYV-------- 349
P LT EG AS +EE+ +L C+A P W ++ + T
Sbjct: 262 PTFLTPEGN-ASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQ 320
Query: 350 IARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPG 409
I +G Y C+A+N+ +V++ P V E TL+C
Sbjct: 321 IIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICR-AN 379
Query: 410 GLPPAQLQWEGPQGPGPTAPSNV-------TWSHAAAQLPSGSVFTC--TGQHPALAPPA 460
G P ++ W P AP + T + Q S +V+ C + ++ L A
Sbjct: 380 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 439
Query: 461 LCTVMLWEP-LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMA 519
V+ P + P + ++ +L C + G P T+ W + GS+
Sbjct: 440 FVNVLAEPPRILTPANTLYQVIANRPALLDCAF-FGSPLPTIEWFKGAK----GSALHED 494
Query: 520 VHLLQ---------AQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEG 570
+++L AQ+D G +TC + L HL+++ P V +P +V++
Sbjct: 495 IYVLHENGTLEIPVAQKDSTGT-YTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 553
Query: 571 GE-AWLECSLRGG-TPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRG 628
G EC ++ T +LWL ++ P F + + + + D D G
Sbjct: 554 GSMVSFECKVKHDHTLSLTVLWLKDNREL--PSDERFTVDKDHLVVA-DVSDDDS----G 606
Query: 629 TYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQLQWAILGPGN----- 683
TY CVA + + S S +L V+ P PP + + VQL W PG+
Sbjct: 607 TYTCVANTTLDSVSASAVLSVVDVPNPP---FDLELTDQLDKSVQLSWT---PGDDNNSP 660
Query: 684 LTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLGGLDPGVLYAFRILALNHHTAGHP 743
+T F+++ + + PG +T S + ++ + L P V Y+FR++A+N P
Sbjct: 661 ITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLK----LSPYVNYSFRVMAVNSIGKSLP 716
Query: 744 SE 745
SE
Sbjct: 717 SE 718
Score = 37.0 bits (84), Expect = 0.078
Identities = 36/147 (24%), Positives = 54/147 (36%), Gaps = 30/147 (20%)
Query: 297 PVITMEPLGLTEEG---FWASEREEVTLSCLAASNPPSHYVWLRDHTQVH---------- 343
P+ ++P +T++ + RE + + C A PP + W R+ T
Sbjct: 33 PLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMK 92
Query: 344 --TGPTYV-IARAGRVHT--GLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVH--- 395
TG + I G+ T G+Y C ARN V I P P
Sbjct: 93 PGTGTLIINIMSEGKAETYEGVYQCTARN-----ERGAAVSNNIVVRPSRSPLWTKEKLE 147
Query: 396 ----PSPEAVTLLCAWPGGLPPAQLQW 418
S +++ L C P GLPP + W
Sbjct: 148 PITLQSGQSLVLPCRPPIGLPPPIIFW 174
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 71.6 bits (174), Expect = 3e-12
Identities = 155/700 (22%), Positives = 253/700 (36%), Gaps = 120/700 (17%)
Query: 160 VEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSA 219
+EG +V TC + EG+ P+ F W H +L E + + ++RTH G+Y C
Sbjct: 39 LEGNRLVLTC-MAEGSWPLEFKWLHNNRELTKFSL----EYRYMITSLDRTHAGFYRCIV 93
Query: 220 SNSVNRLSSDGAFLDVIYLAT-RTCYKKKSVSG-----IRLLDGAGL-----------RR 262
N + L + V Y+ + K +SVS IR A R+
Sbjct: 94 RNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRK 153
Query: 263 FKERGRMASYLS-----VFTVAV-CGNCELRTVEADGPDKPVITMEPLGLTEEGFWA--- 313
R+A L + TVA G ++ V D T +P+ LT E
Sbjct: 154 IPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNK--TSQPITLTVENVGGPAD 211
Query: 314 ----------------SEREEVTLSCLAASNP--PSHYVWLRDHTQVHTGPT-----YVI 350
+ EVTL C+A + P H +W +D + G + I
Sbjct: 212 PIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTI 271
Query: 351 ARAGRVHTGLYTCLA--RNSYLDTRTQTTVQLTIYYPPE--GQPSCAVHPSPEAVTLLCA 406
G Y C A R+S + + + L++ PP+ +P + E V +
Sbjct: 272 PNPTGSDAGYYECEAVLRSSSVPSVVRGAY-LSVLEPPQFVKEPERHITAEMEKVVDIPC 330
Query: 407 WPGGLPPAQLQW-------------------EGPQGPGPTAPSNVTWSHAAAQLPSGSVF 447
G+PP + W +G P + A+ +G V
Sbjct: 331 QAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQ 390
Query: 448 TCTGQHPALAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQ 507
T T LA ++ + PL + + ++L+CE G PA + W +
Sbjct: 391 TST----YLAVTSIAPNITRGPL------DSTVIDGMSVVLACETSGAPRPA-ITWQKGE 439
Query: 508 QQPLGGS----------SSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQ 557
+ GS S S+ + + AG +TC T+ + L + A
Sbjct: 440 RILASGSVQLPRFTPLESGSLLISPTHISD--AGT-YTCLATNSRGVDEASADLVVWART 496
Query: 558 LDVAEPR-VSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRL 616
P+ SV++G +A + C + P + ++ + D T G HP R
Sbjct: 497 RITKPPQDQSVIKGTQASMVCGVTHD-PRVTIRYIWEK----DGATLGTESHPRIRLDRN 551
Query: 617 GIYDADPAHHR--GTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQL 674
G GTY C +A GN S+S L V + P P ++ L+ RR + L
Sbjct: 552 GSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLS-TVERRAINL 610
Query: 675 QWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLGGLDPGVLYAFRILA 734
W GN + R + W + ++P++ + GL P Y FR+ A
Sbjct: 611 TWTKPFDGNSP---LIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCA 667
Query: 735 LNHHTAGHPSE----VKIPADPPFSAYPAVLGAAGTGMVV 770
+N G S+ V +P +PP + V+ + T +
Sbjct: 668 VNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSI 707
Score = 40.4 bits (93), Expect = 0.007
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 12/96 (12%)
Query: 653 PAPPNVTISRLTYGRHRREVQLQWAILGPGN--LTGFLVQRKASALGPGAGAWETAASDI 710
P PP V I R+ + + W+ PG +T ++++ + S G W+ DI
Sbjct: 1825 PGPPGVPI----IVRYSSAIAIHWSSGDPGKGPITRYVIEARPS----DEGLWDILIKDI 1876
Query: 711 EPE--SRGRRLGGLDPGVLYAFRILALNHHTAGHPS 744
E S + L PGV Y FR++A+N + G PS
Sbjct: 1877 PKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPS 1912
Score = 38.5 bits (88), Expect = 0.027
Identities = 34/140 (24%), Positives = 54/140 (38%), Gaps = 12/140 (8%)
Query: 285 ELRTVEADGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWL---RDHTQ 341
++R A P EP+ E + L+C+A + P + WL R+ T+
Sbjct: 14 QIRAARAQDDVSPYFKTEPVRTQVH----LEGNRLVLTCMAEGSWPLEFKWLHNNRELTK 69
Query: 342 VHTGPTYVIARAGRVHTGLYTCLARN---SYLDTRTQTTVQLTIYYPPEGQPSCAVHPSP 398
Y+I R H G Y C+ RN + L +T+ V + EG+ +V
Sbjct: 70 FSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSF-EEGEKHQSVSHG- 127
Query: 399 EAVTLLCAWPGGLPPAQLQW 418
EA + P Q+ W
Sbjct: 128 EAAVIRAPRIASFPQPQVTW 147
Score = 30.8 bits (68), Expect = 5.6
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Query: 653 PAPP-NVTISRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIE 711
P PP N+ IS + G +Q + G +++ +LV+ + +G G E
Sbjct: 993 PGPPTNLGISNI--GPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNE 1050
Query: 712 PESRGRRLGGLDPGVLYAFRILALNHHTAGHPSE 745
P++R + L+P Y+FR+ +N PS+
Sbjct: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQ 1084
>gi|81158226 neuronal cell adhesion molecule isoform A precursor
[Homo sapiens]
Length = 1304
Score = 70.5 bits (171), Expect = 6e-12
Identities = 115/489 (23%), Positives = 193/489 (39%), Gaps = 68/489 (13%)
Query: 303 PLGLTEEGFWASEREEV-----TLSCLAASNPPSHYVWLRDHTQVHTGPTYV-------- 349
P LT EG AS +EE+ +L C+A P W ++ + T
Sbjct: 268 PTFLTPEGN-ASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQ 326
Query: 350 IARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPG 409
I +G Y C+A+N+ +V++ P V E TL+C
Sbjct: 327 IIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICR-AN 385
Query: 410 GLPPAQLQWEGPQGPGPTAPSNV-------TWSHAAAQLPSGSVFTC--TGQHPALAPPA 460
G P ++ W P AP + T + Q S +V+ C + ++ L A
Sbjct: 386 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 445
Query: 461 LCTVMLWEP-LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMA 519
V+ P + P + ++ +L C + G P T+ W + GS+
Sbjct: 446 FVNVLAEPPRILTPANTLYQVIANRPALLDCAF-FGSPLPTIEWFKGAK----GSALHED 500
Query: 520 VHLLQ---------AQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEG 570
+++L AQ+D G +TC + L HL+++ P V +P +V++
Sbjct: 501 IYVLHENGTLEIPVAQKDSTGT-YTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 559
Query: 571 GE-AWLECSLRGG-TPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRG 628
G EC ++ T +LWL ++ P F + + + + D D G
Sbjct: 560 GSMVSFECKVKHDHTLSLTVLWLKDNREL--PSDERFTVDKDHLVVA-DVSDDDS----G 612
Query: 629 TYQCVARNAVGNSSQSVLLEVLR---YPAP----PNVTISRLTYGRHRREVQLQWAILGP 681
TY CVA + + S S +L V+ PAP PN + + VQL W P
Sbjct: 613 TYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWT---P 669
Query: 682 GN-----LTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLGGLDPGVLYAFRILALN 736
G+ +T F+++ + + PG +T S + ++ + L P V Y+FR++A+N
Sbjct: 670 GDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLK----LSPYVNYSFRVMAVN 725
Query: 737 HHTAGHPSE 745
PSE
Sbjct: 726 SIGKSLPSE 734
Score = 35.8 bits (81), Expect = 0.17
Identities = 36/144 (25%), Positives = 51/144 (35%), Gaps = 31/144 (21%)
Query: 297 PVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVH------------T 344
P IT + + + + RE + + C A PP + W R+ T T
Sbjct: 46 PTITQQ----SPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGT 101
Query: 345 GPTYV-IARAGRVHT--GLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVH------ 395
G + I G+ T G+Y C ARN V I P P
Sbjct: 102 GTLIINIMSEGKAETYEGVYQCTARN-----ERGAAVSNNIVVRPSRSPLWTKEKLEPIT 156
Query: 396 -PSPEAVTLLCAWPGGLPPAQLQW 418
S +++ L C P GLPP + W
Sbjct: 157 LQSGQSLVLPCRPPIGLPPPIIFW 180
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 68.9 bits (167), Expect = 2e-11
Identities = 97/372 (26%), Positives = 144/372 (38%), Gaps = 53/372 (14%)
Query: 319 VTLSCLAASNPPSHYVWLRDHTQVHTG--PTYVIARAGRVHT---------GLYTCLARN 367
V L+C A P +WL+D V P + GRV T G Y+C+A +
Sbjct: 804 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 863
Query: 368 SYLDTRTQTTVQLTIYYPPE--GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPG 425
+ + R +Q ++ PP G+ + E+V L C PP W+ +
Sbjct: 864 AVGEDRQDVVLQ--VHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLE 921
Query: 426 PTAPSNVTWSHAAAQLPSGSV-----FTCTGQHPALAPPALCTVMLWEPLGRPTCWS-TA 479
P +++ A Q+ V +TC + A + +W P S T
Sbjct: 922 PRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTL 981
Query: 480 TMGDQF-IMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMA--------VHLLQAQEDLA 530
T+ + LSCE G P + W + Q PL G + + ++L QAQ
Sbjct: 982 TVREGHPTSLSCECRG-VPFPKISWRKDGQ-PLPGEGAGLQHVSAVGRLLYLGQAQLAQE 1039
Query: 531 GREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-----VSVLEGGEAWLECSLRGGTPP 585
G +TC ++++ L++ P +A PR VSV++ G A LEC+ G PP
Sbjct: 1040 GT-YTCECSNVVGNSSQDLQLEVHVPP-QIAGPREPPTQVSVVQDGVATLECNATGKPPP 1097
Query: 586 AQLLWLGPQQQKVDPG----TSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNS 641
Q + G G LH E AQ A H G Y CVA N G +
Sbjct: 1098 TVTWERDGQPVGAELGLQLQNQGQSLHVERAQ----------AAHTGRYSCVAENLAGRA 1147
Query: 642 SQSVLLEVLRYP 653
+ L VL P
Sbjct: 1148 ERKFELSVLVPP 1159
Score = 67.4 bits (163), Expect = 5e-11
Identities = 94/374 (25%), Positives = 136/374 (36%), Gaps = 44/374 (11%)
Query: 315 EREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV---------HTGLYTCLA 365
E VTL CLA+ PP W + H V + ++ GRV G Y C+A
Sbjct: 708 ENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVA 767
Query: 366 RNSYLDTRTQTTVQLTIYYPPE-----GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQW-- 418
N + T+ L + PP P + +P V L C G P L W
Sbjct: 768 SN--VAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTP--VRLTCN-ATGAPSPTLMWLK 822
Query: 419 -EGPQGPGPTA-----PSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP--- 469
P P T P + A+A+ ++C + + P
Sbjct: 823 DGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSI 882
Query: 470 LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQ-QPLGGSSSSMAVHLLQAQ-- 526
LG + + + ++ + L C+ PP W D + +P G S LLQ
Sbjct: 883 LGEEL--NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRA 940
Query: 527 EDLAGREFTCRGTHLLRTPDPHCHLQL-EAPQLDVAEPR-VSVLEGGEAWLECSLRGGTP 584
+ +TC + + H +L + AP + E ++V EG L C R G P
Sbjct: 941 DVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECR-GVP 999
Query: 585 PAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQS 644
++ W Q PG + H L + A A GTY C N VGNSSQ
Sbjct: 1000 FPKISWRKDGQPL--PGEGAGLQHVSAVGRLLYLGQAQLA-QEGTYTCECSNVVGNSSQD 1056
Query: 645 VLLEVLRYPAPPNV 658
+ LEV PP +
Sbjct: 1057 LQLEV---HVPPQI 1067
Score = 67.4 bits (163), Expect = 5e-11
Identities = 90/398 (22%), Positives = 149/398 (37%), Gaps = 69/398 (17%)
Query: 295 DKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVH----------- 343
+ P I P LT + L C A+ +P VW +D ++
Sbjct: 2571 EPPAIAPSPSNLT-----LTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLL 2625
Query: 344 TGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTL 403
++ G + + C+ N + Q+T++ PP + A + VT+
Sbjct: 2626 PSNALLLTAPGPQDSAQFECVVSNEVGEAHR--LYQVTVHVPP----TIADDQTDFTVTM 2679
Query: 404 LCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQL----------PSGSV------- 446
+ P L P PT V+WS A AQL PSG++
Sbjct: 2680 MA-------PVVLTCHSTGIPAPT----VSWSKAGAQLGARGSGYRVSPSGALEIGQALP 2728
Query: 447 -----FTCTGQHPA-LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPAT 500
+TC+ ++ A +A + + P+ +P + ++ ++L CE G P T
Sbjct: 2729 IHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 2787
Query: 501 LGWLDEQQQPLGGSSSSMA----VHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAP 556
+ W E G S+ + + + A + AG + C + + L ++ P
Sbjct: 2788 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGN-YLCIAKNSAGSAMGKTRLVVQVP 2846
Query: 557 Q-LDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLR 615
++ P +S EG A+L C RG +P + W Q V F + P G L
Sbjct: 2847 PVIENGLPDLSTTEGSHAFLPCKARG-SPEPNITW-DKDGQPVSGAEGKFTIQPSGELLV 2904
Query: 616 LGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYP 653
+ D GTY C A NAVG + + V L +L P
Sbjct: 2905 KNLEGQDA----GTYTCTAENAVGRARRRVHLTILVLP 2938
Score = 65.5 bits (158), Expect = 2e-10
Identities = 115/473 (24%), Positives = 176/473 (37%), Gaps = 111/473 (23%)
Query: 256 DGAGLRRFKERGRMASYLSVFTVAVCGN--CELRTV----------EADGPDKPVITMEP 303
+GAGL+ GR+ YL +A G CE V E P + EP
Sbjct: 1015 EGAGLQHVSAVGRLL-YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREP 1073
Query: 304 ---LGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQV---------HTGPTYVIA 351
+ + ++G TL C A PP W RD V + G + +
Sbjct: 1074 PTQVSVVQDGV-------ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVE 1126
Query: 352 RAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPE--------GQPSCAVHPSPEAVTL 403
RA HTG Y+C+A N L R + +L++ PPE + A+H SP +TL
Sbjct: 1127 RAQAAHTGRYSCVAEN--LAGRAERKFELSVLVPPELIGDLDPLTNITAALH-SP--LTL 1181
Query: 404 LCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAA--------QLPSGSVFTCTGQHPA 455
LC G+PP ++W +G P +P T+ A Q +++C + A
Sbjct: 1182 LCE-AMGIPPPAIRWF--RGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 1238
Query: 456 -----------LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWL 504
L PP++ L E + + Q L C G P L W
Sbjct: 1239 GEARRNFSVEVLVPPSIENEDLEEVI--------KVLDGQTAHLMCNVTG-HPQPKLTWF 1289
Query: 505 DEQQQPLGG-----SSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQ-LEAPQL 558
+ + G S + + +LQA AG ++C + + H L L AP +
Sbjct: 1290 KDGRPLARGDAHHISPDGVLLQVLQANLSSAGH-YSCIAANAVGEKTKHFQLSVLLAPTI 1348
Query: 559 -----DVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWL-------GPQQQKVDPGTSGFM 606
D A+ V+V L C P + W+ + ++ PGT G
Sbjct: 1349 LGGAEDSADEEVTVTVNNPISLICEALA-FPSPNITWMKDGAPFEASRNIQLLPGTHGLQ 1407
Query: 607 LHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVT 659
+ L DA G Y CV N +G + ++ +EVL PP+++
Sbjct: 1408 I------LNAQKEDA------GQYTCVVTNELGEAVKNYHVEVL---IPPSIS 1445
Score = 61.2 bits (147), Expect = 4e-09
Identities = 139/605 (22%), Positives = 211/605 (34%), Gaps = 105/605 (17%)
Query: 127 VAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTFAWQHRA 186
VA Q +A TL V VP + L + + +SV C V P ++
Sbjct: 1726 VAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ 1785
Query: 187 PRGLGEA--LVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLATRTCY 244
LGE L+ T L QL + G Y C A N+ R ++ A R
Sbjct: 1786 ALSLGEEVFLLPGTHTL-QLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAP 1844
Query: 245 K-KKSVSGIRLLDGAGLRRFKE----------RGRMASYLSVFTVAVCGNCELRTVEADG 293
+ + +R+ D A L + + L+ T A+ G L EA
Sbjct: 1845 RGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQV 1904
Query: 294 PDKPVITMEPLGLTEEG-------------FWASEREEVT--------LSCLAASNPPSH 332
DK + + + + E F + E V+ L+C + P
Sbjct: 1905 SDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT 1964
Query: 333 YVWLRDHTQVHTGPTY-VIARAGRVH--------TGLYTCLARNSYLDTRTQTTVQLTIY 383
WL+D V + + V++R GR+ G YTC+A N+ + R V + +
Sbjct: 1965 VTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVA 2024
Query: 384 YPPEGQPSCAVHPSPEA--VTLLCAWPGGLPPAQLQWEGPQGP-----GPTAPSNVTWSH 436
H E V L C G PP + W P GP H
Sbjct: 2025 PRIRSSGVAREHHVLEGQEVRLDCE-ADGQPPPDVAWLKDGSPLGQDMGP---------H 2074
Query: 437 AAAQLPSGSV------------FTCTGQHPALAPPALCTVMLWEP----LGRPTCWSTAT 480
L GS+ +TC +PA L TV + P G + +
Sbjct: 2075 LRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVS 2134
Query: 481 MGDQFIMLSCEWPGGEPPATLGWLDE-------QQQPLGGSSSSMAVHLLQAQEDLAGRE 533
+ + + C G PP + WL + Q+ L GS ++ + +Q + AG
Sbjct: 2135 RPGELVTMVCP-VRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLAD--AG-I 2190
Query: 534 FTCRGTHLLRTPDPHCHLQLEAPQLDVAEP-----RVSVLEGGEAWLECSLRGGTPPAQL 588
FTC D + LQ++ P V EP V V+ G L C R G P +
Sbjct: 2191 FTCVAASPAGVADRNFTLQVQVP--PVLEPVEFQNDVVVVRGSLVELPCEAR-GVPLPLV 2247
Query: 589 LWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLE 648
W+ + + +G L+L +A A GTY CVA + G + + L
Sbjct: 2248 SWMKDGEPLLSQSLE------QGPSLQL---EAVGAGDSGTYSCVAVSEAGEARRHFQLT 2298
Query: 649 VLRYP 653
V+ P
Sbjct: 2299 VMEPP 2303
Score = 60.5 bits (145), Expect = 7e-09
Identities = 87/367 (23%), Positives = 139/367 (37%), Gaps = 32/367 (8%)
Query: 319 VTLSCLAASNPPSHYVWLRD-----HTQVHTGPTYVIARAGRVHTGLYTCLARNSYLDTR 373
V L C A P W++D + GP+ + G +G Y+C+A + + R
Sbjct: 2233 VELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 2292
Query: 374 TQTTVQLTIYYPPE----GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAP 429
QLT+ PP GQP+ + LLC G P + W G T
Sbjct: 2293 RH--FQLTVMEPPHIEDSGQPTELSLTPGAPMELLCD-AQGTPQPNITWH-KDGQALTRL 2348
Query: 430 SNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP---LGRPTCWSTATMGDQFI 486
N + + ++ ++TC + PA A V + P +G + +
Sbjct: 2349 ENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL 2408
Query: 487 MLSCEWPGGEPPATLGWLDE----QQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLL 542
+L C EP + W + Q+ LQA +++C +
Sbjct: 2409 VLECSVEA-EPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAA 2467
Query: 543 RTPDPHCHLQLEA-PQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPG 601
+ +++ P + P V+V A L C G PA L+ + +DP
Sbjct: 2468 GSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADG--VPAPLVSWRKDRVPLDPR 2525
Query: 602 TSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPA----PPN 657
+ F + PEG+ LR+ A A H Y C+A N+ G+ Q L VL PA P N
Sbjct: 2526 SPRFEILPEGS-LRIQPVLAQDAGH---YLCLASNSAGSDRQGRDLRVLEPPAIAPSPSN 2581
Query: 658 VTISRLT 664
+T++ T
Sbjct: 2582 LTLTAHT 2588
Score = 60.1 bits (144), Expect = 9e-09
Identities = 141/622 (22%), Positives = 224/622 (36%), Gaps = 91/622 (14%)
Query: 107 LVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVV 166
L + E +G + C+V +VAG A TL V VP + + S V G+ +V
Sbjct: 1897 LEIQEAQVSDKGLYSCKVSNVAG----EAVRTFTLTVQVPPTFENPKTETVSQVAGSPLV 1952
Query: 167 ATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEP--LFQLDPVNRTHLGWYMCSASNS-- 222
TC V G T W A+ GV QL + G Y C A N+
Sbjct: 1953 LTCDV-SGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQA 2011
Query: 223 ------------VNRLSSDGAFLDVIYLATRTCYKKKSVSGIRLLDGAGLRRFKERGR-- 268
R+ S G + L + G D A L+ G+
Sbjct: 2012 EARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM 2071
Query: 269 ---MASYLSVFTVAVCGNCELRTVEAD----------GPDKPVITMEPL-------GLTE 308
+ YL ++ + G LR +A G D + T+ L G
Sbjct: 2072 GPHLRFYLDGGSLVLKG---LRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADG 2128
Query: 309 EGFWASEREE-VTLSCLAASNPPSHYVWLRD--------HTQVH-TGPTYVIARAGRVHT 358
G S E VT+ C +PP H WL+D T +H +G T I++
Sbjct: 2129 SGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADA 2188
Query: 359 GLYTCLARNSYLDTRTQTTVQLTIYYPPEGQP----SCAVHPSPEAVTLLCAWPGGLPPA 414
G++TC+A + T+Q+ + PP +P + V V L C G+P
Sbjct: 2189 GIFTCVAASPAGVADRNFTLQVQV--PPVLEPVEFQNDVVVVRGSLVELPCE-ARGVPLP 2245
Query: 415 QLQW--EGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP--- 469
+ W +G + + A ++C A + + EP
Sbjct: 2246 LVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHI 2305
Query: 470 --LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQE 527
G+PT S ++ + G P + W + Q ++S A +L+ ++
Sbjct: 2306 EDSGQPTELSLTPGAPMELLCDAQ---GTPQPNITWHKDGQALTRLENNSRATRVLRVRD 2362
Query: 528 DLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR----VSVLEGGEAWLECSLRGGT 583
AG +TC + ++++AP ++ PR V L G+ LECS+
Sbjct: 2363 --AGL-YTCLAESPAGAIEKSFRVRVQAPP-NIVGPRGPRFVVGLAPGQLVLECSVEA-E 2417
Query: 584 PPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQ 643
P ++ W + + F QL+ + AD G Y C ARNA G++S
Sbjct: 2418 PAPKITWHRDGIVLQEDAHTQFPERGRFLQLQ-ALSTADS----GDYSCTARNAAGSTSV 2472
Query: 644 SVLLEVLRYP----APPNVTIS 661
+ +E+ P PP V +S
Sbjct: 2473 AFRVEIHTVPTIRSGPPAVNVS 2494
Score = 58.2 bits (139), Expect = 3e-08
Identities = 135/598 (22%), Positives = 206/598 (34%), Gaps = 107/598 (17%)
Query: 98 GVVSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVS-KPQVRLSN 156
GV L SL L + G + CQ + G A L V VP S + R +N
Sbjct: 50 GVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRA----KLVVYVPPSIREDGRKAN 105
Query: 157 PSPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYM 216
S + G S+ C P W A LVGV P+ GW +
Sbjct: 106 VSGMAGQSLTLECDANGFPVP-EIVWLKDAQ------LVGV--------PLGWAGYGWDL 150
Query: 217 CSASNSVNRLSSDGAFLDVIYLATRTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVF 276
+RL +G +S+ R+ G RR + G A + +
Sbjct: 151 GWGQVGGHRLLDEG----------------QSLHFPRIQPGRSGRRGAQAGGSAQTKAPW 194
Query: 277 TVAVCGNCELRTVEADGPDKPVITM------EPLGLTEEGFWASEREEVTLSCLAASNPP 330
+ G + T A P P + E LGL +V L C + P
Sbjct: 195 XAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVLGLAGA--------DVELQCWTSGVPT 246
Query: 331 SHYVWLRDHTQVHTG-PTYVIARAGRV---------HTGLYTCLARNSYLDTRTQTTVQL 380
W +D V G P + G+V G Y C+A + + QL
Sbjct: 247 PQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPA--GQQARDFQL 304
Query: 381 TIYYPP----EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSH 436
++ PP + V LLC G+P + W PT+ + V ++
Sbjct: 305 RVHAPPTIWGSNETGEVAVMEDHLVQLLCE-ARGVPTPNITWFKDGALLPTS-TKVVYTR 362
Query: 437 AAAQLPSG-------SVFTCTGQHPALAPPALCTVMLWEPL------GRPTCWSTATMGD 483
QL G V+TC + A + ++ P GRP + +
Sbjct: 363 GGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRP--YVVKAVAG 420
Query: 484 QFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSM-----AVHLLQAQEDLAGREFTCRG 538
+ + L C G P TL W E P+ S+ S +V L++ + + ++C
Sbjct: 421 RPVALECV-ARGHPSPTLSWHHEGL-PVAESNESRLETDGSVLRLESPGEASSGLYSC-- 476
Query: 539 THLLRTPDPHCHLQLEA-----PQLDVAEP--RVSVLEGGEAWLECSLRGGTPPAQLLWL 591
+ +P LQ PQL VAE +V+ + G L C G+P + WL
Sbjct: 477 --VASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQA-SGSPVPTIQWL 533
Query: 592 GPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEV 649
Q + +G + +G L + + D H G + C A N G + V + V
Sbjct: 534 --QNGRPAEELAGVQVASQGTTLHIDHVELD---HSGLFACQATNEAGTAGAEVEVSV 586
Score = 55.1 bits (131), Expect = 3e-07
Identities = 90/391 (23%), Positives = 142/391 (36%), Gaps = 55/391 (14%)
Query: 305 GLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGP---------TYVIARAGR 355
GL E A V+L C ++P W +D + G T + RA
Sbjct: 1750 GLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARL 1809
Query: 356 VHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQ-----PSCAVHPSPEAVTLLCAWPGG 410
+G+YTC A N+ R Q VQL++ PP + P AV +L
Sbjct: 1810 SDSGMYTCEALNA--AGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDA 1867
Query: 411 LPPAQLQWEGPQGPGPTAPSNVTWSHA------AAQLPSGSVFTCTGQHPALAPPALCTV 464
LP + W P A AQ+ +++C + A T+
Sbjct: 1868 LPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTL 1927
Query: 465 MLWEP--LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHL 522
+ P P + + + ++L+C+ G P T+ WL ++ S AVH
Sbjct: 1928 TVQVPPTFENPKTETVSQVAGSPLVLTCD-VSGVPAPTVTWLKDRM-----PVESSAVHG 1981
Query: 523 LQAQE---DLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRV---------SVLEG 570
+ ++ L+ + GT+ + + + + PR+ VLEG
Sbjct: 1982 VVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEG 2041
Query: 571 GEAWLECSLRGGTPPAQLLWL---GPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHR 627
E L+C G PP + WL P Q + P ++ +G L L A A
Sbjct: 2042 QEVRLDCE-ADGQPPPDVAWLKDGSPLGQDMGPHLRFYL---DGGSLVLKGLRASDA--- 2094
Query: 628 GTYQCVARNAVGNSSQSVLLEVLRYPAPPNV 658
G Y CVA N G ++ + VL PP +
Sbjct: 2095 GAYTCVAHNPAGEDARLHTVNVL---VPPTI 2122
Score = 53.9 bits (128), Expect = 6e-07
Identities = 135/619 (21%), Positives = 219/619 (35%), Gaps = 110/619 (17%)
Query: 118 GHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLS--NPSPVEGASVVATCAVREGT 175
G + C ++AG + + L VLVP P + N + +E ASV C + G
Sbjct: 670 GIYTCAATNLAG----ESKREVALKVLVP---PNIEPGPVNKAVLENASVTLEC-LASGV 721
Query: 176 EPVTFAW--QHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVN--------- 224
P +W H+ V V + +++ + G Y C ASN
Sbjct: 722 PPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLR 781
Query: 225 -----RLSSDGAFLDVIYLATR---TCYKKKSVSG--IRLLDG--------AGLRRFKER 266
R++ + + + T TC + S + L DG GL+ F
Sbjct: 782 VNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPG- 840
Query: 267 GRMASYLSVFTVAVCGNCELRTVEADGPDKPVITME----PLGLTEE-GFWASEREEVTL 321
GR+ + S + G V A G D+ + ++ P L EE E V L
Sbjct: 841 GRVLTLASA-RASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVAL 899
Query: 322 SCLAASNPPSHYVWLRDHTQVHTGPTYVIA---------RAGRVHTGLYTCLARNSYLDT 372
C + + PP W +D + P ++ RA G YTC A N
Sbjct: 900 ECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQA--G 957
Query: 373 RTQTTVQLTIYYPP-----EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPT 427
R++ L ++ P E P +++ C G+P ++ W P P
Sbjct: 958 RSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECR---GVPFPKISWRKDGQPLPG 1014
Query: 428 APSNVTWSHAA--------AQLPSGSVFTCTG-----------QHPALAPPALCTVMLWE 468
+ + A AQL +TC Q PP +
Sbjct: 1015 EGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAG----- 1069
Query: 469 PLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGS------SSSMAVHL 522
P PT + + D L C G+PP T+ W + QP+G + ++H+
Sbjct: 1070 PREPPT--QVSVVQDGVATLECN-ATGKPPPTVTW-ERDGQPVGAELGLQLQNQGQSLHV 1125
Query: 523 LQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAE----PRVSVLEGGEAWLECS 578
+AQ GR ++C +L + L + P + + ++ L C
Sbjct: 1126 ERAQAAHTGR-YSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCE 1184
Query: 579 LRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAV 638
G PPA + G ++ V PG ++L G L++ G Y C+A N
Sbjct: 1185 AMGIPPPAIRWFRG--EEPVSPGEDTYLL-AGGWMLKM---TQTQEQDSGLYSCLASNEA 1238
Query: 639 GNSSQSVLLEVLRYPAPPN 657
G + ++ +EVL P+ N
Sbjct: 1239 GEARRNFSVEVLVPPSIEN 1257
Score = 48.5 bits (114), Expect = 3e-05
Identities = 88/380 (23%), Positives = 141/380 (37%), Gaps = 59/380 (15%)
Query: 315 EREEVTLSCLAASNPPSHYVWLRDHTQVH-----------TGPTYVIARAGRVHTGLYTC 363
E +LSC P W +D + G + +A G YTC
Sbjct: 985 EGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTC 1044
Query: 364 LARNSYLDTRTQTTVQLTIYYPPE----GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWE 419
N + + +QL ++ PP+ +P V + V L G PP + WE
Sbjct: 1045 ECSN--VVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWE 1102
Query: 420 GPQGP-----GPTAPSNVTWSHAA-AQLPSGSVFTCTGQHPA-----------LAPPALC 462
P G + H AQ ++C ++ A L PP L
Sbjct: 1103 RDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELI 1162
Query: 463 TVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMA--- 519
+ +PL TA + +L CE G PPA + E+ G + +A
Sbjct: 1163 GDL--DPLTN----ITAALHSPLTLL-CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGW 1215
Query: 520 -VHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAP---QLDVAEPRVSVLEGGEAWL 575
+ + Q QE +G ++C ++ + +++ P + + E + VL+G A L
Sbjct: 1216 MLKMTQTQEQDSGL-YSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHL 1274
Query: 576 ECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLH--PEGAQLRLGIYDADPAHHRGTYQCV 633
C++ G P +L W + P G H P+G L++ + A H Y C+
Sbjct: 1275 MCNVTGHPQP-KLTWFKDGR----PLARGDAHHISPDGVLLQVLQANLSSAGH---YSCI 1326
Query: 634 ARNAVGNSSQSVLLEVLRYP 653
A NAVG ++ L VL P
Sbjct: 1327 AANAVGEKTKHFQLSVLLAP 1346
Score = 48.1 bits (113), Expect = 3e-05
Identities = 165/696 (23%), Positives = 228/696 (32%), Gaps = 137/696 (19%)
Query: 37 PVEEVVSVQGVRGGSVELACGSGPAPL-LVLWSFTPLGSLVPRPVAVTDGAMSKVEAIAS 95
PVE V VRG VEL C + PL LV W + DG +++
Sbjct: 2218 PVEFQNDVVVVRGSLVELPCEARGVPLPLVSW--------------MKDGEPLLSQSLE- 2262
Query: 96 ALGVVSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLS 155
+ SL L + G G + C + AG A H L V+ P P + S
Sbjct: 2263 -------QGPSLQLEAVGAGDSGTYSCVAVSEAG----EARRHFQLTVMEP---PHIEDS 2308
Query: 156 NP----SPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTH 211
S GA + C +GT W G+AL + +
Sbjct: 2309 GQPTELSLTPGAPMELLCDA-QGTPQPNITWHKD-----GQALTRLENNSRATRVLRVRD 2362
Query: 212 LGWYMCSASNSVNRLSSDGAFLD--------------VIYLATRTCYKKKSVS------- 250
G Y C A + + V+ LA + SV
Sbjct: 2363 AGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKI 2422
Query: 251 -----GIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDK-----PVIT 300
GI L + A + F ERGR L + A G+ A G + T
Sbjct: 2423 TWHRDGIVLQEDAHTQ-FPERGRFLQ-LQALSTADSGDYSCTARNAAGSTSVAFRVEIHT 2480
Query: 301 MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHT-GPTYVIARAGRVH-- 357
+ + S + L C A P W +D + P + I G +
Sbjct: 2481 VPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQ 2540
Query: 358 ------TGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGL 411
G Y CLA NS R L + PP A+ PSP +TL P L
Sbjct: 2541 PVLAQDAGHYLCLASNSAGSDRQGR--DLRVLEPP------AIAPSPSNLTLTAHTPALL 2592
Query: 412 P--------PAQLQWEG--------PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPA 455
P P + W+ QG PSN A S F C +
Sbjct: 2593 PCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQ-FECVVSNEV 2651
Query: 456 LAPPALCTVMLWEPLGRPTCWS-----TATMGDQFIMLSCEWPGGEPPATLGWLDEQQQP 510
L V + P PT T TM ++L+C G P T+ W Q
Sbjct: 2652 GEAHRLYQVTVHVP---PTIADDQTDFTVTMMAP-VVLTCH-STGIPAPTVSWSKAGAQ- 2705
Query: 511 LGGSSS------SMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR 564
LG S S A+ + QA AGR +TC + H L ++A V +P
Sbjct: 2706 LGARGSGYRVSPSGALEIGQALPIHAGR-YTCSARNSAGVAHKHVFLTVQASP--VVKPL 2762
Query: 565 VSVLEG---GEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDA 621
SV+ E L C G P + W Q++ ++ T G QLR+
Sbjct: 2763 PSVVRAVAEEEVLLPCEA-SGIPRPTITW---QKEGLNVATGVSTQVLPGGQLRIAHASP 2818
Query: 622 DPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPN 657
+ A G Y C+A+N+ G++ L V P N
Sbjct: 2819 EDA---GNYLCIAKNSAGSAMGKTRLVVQVPPVIEN 2851
Score = 46.2 bits (108), Expect = 1e-04
Identities = 91/388 (23%), Positives = 132/388 (34%), Gaps = 66/388 (17%)
Query: 319 VTLSCLAASNPPSHYVWLRDHTQVHT---------GPTYVIARAGRVHTGLYTCLARNSY 369
V L C+A +P W + V G + G +GLY+C+A +
Sbjct: 423 VALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPA 482
Query: 370 LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWP-------GGLPPAQLQWEGPQ 422
+ Q +V++ + P V VT + P G P +QW
Sbjct: 483 GEAVLQYSVEVQV------PPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 536
Query: 423 GP-----GPTAPSNVTWSHAA-AQLPSGSVFTCTGQHPALAPPALCTVML---WEPLGRP 473
P G S T H +L +F C + A A V + W P
Sbjct: 537 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLE 596
Query: 474 TCWSTATMGDQF---IMLSCEWP-------GGEPPATLGWLDEQQ---QPLGGSSSSMAV 520
G + +C+ P +PP GW +P G +
Sbjct: 597 VPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLP 656
Query: 521 HLLQAQE-DLAGRE-FTCRGTHLLRTPDPHCHLQ-LEAPQLDVAEPRVSVLEGGEAWLEC 577
LQ ++ DL +TC T+L L+ L P ++ +VLE LEC
Sbjct: 657 PPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLEC 716
Query: 578 SLRGGTPPAQLLWLGPQQ-----QKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQC 632
G PP + W Q V G +L E AQL DA G+Y+C
Sbjct: 717 LAS-GVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLS----DA------GSYRC 765
Query: 633 VARNAVGNSSQSVLLEVLRYPAPPNVTI 660
VA N G++ L LR PP +T+
Sbjct: 766 VASNVAGSTE---LRYGLRVNVPPRITL 790
Score = 45.8 bits (107), Expect = 2e-04
Identities = 71/288 (24%), Positives = 106/288 (36%), Gaps = 47/288 (16%)
Query: 401 VTLLCAWPGGLPPAQLQWEGPQGPG-PTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPP 459
V L C W G+P Q++W + P P P H Q G V TG H
Sbjct: 235 VELQC-WTSGVPTPQVEWTKDRQPVLPGGP------HLQVQ-EDGQVLRITGSHVGDEGR 286
Query: 460 ALCTVMLWEPLGR------------PTCWST------ATMGDQFIMLSCEWPGGEPPATL 501
C + + P G+ PT W + A M D + L CE G P
Sbjct: 287 YQC--VAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNIT 344
Query: 502 GWLDEQQQPLGG----SSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEA-P 556
+ D P + + L +AQ AG +TC+ ++ + + L + P
Sbjct: 345 WFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAG-VYTCKASNAVGAAEKATRLDVYVPP 403
Query: 557 QLDVAEPR---VSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQ 613
++ A R V + G LEC RG P L W + S L +G+
Sbjct: 404 TIEGAGGRPYVVKAVAGRPVALECVARGHPSPT-LSWHHEGLPVAESNES--RLETDGSV 460
Query: 614 LRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTIS 661
LRL ++ G Y CVA + G ++VL + PP + ++
Sbjct: 461 LRL---ESPGEASSGLYSCVASSPAG---EAVLQYSVEVQVPPQLLVA 502
Score = 44.7 bits (104), Expect = 4e-04
Identities = 87/371 (23%), Positives = 136/371 (36%), Gaps = 52/371 (14%)
Query: 314 SEREEVTLSCLAASNPPSHYVWLRDHTQVHTGP-TYVIARAGRV--------HTGLYTCL 364
+E L C A +P + W +D V + I +G + G YTC
Sbjct: 2859 TEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCT 2918
Query: 365 ARNSYLDTRTQTTVQLTIYYPP-----EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWE 419
A N+ R + V LTI P G S + + + L CA G P ++ W
Sbjct: 2919 AENAV--GRARRRVHLTILVLPVFTTLPGDRSLRLG---DRLWLRCAARGS-PTPRIGWT 2972
Query: 420 GPQGPGPTAPSNV----TWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP---LGR 472
P S T AA + C ++ A+ V + E G
Sbjct: 2973 VNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 3032
Query: 473 PTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGS-------SSSMAVHLLQA 525
+ +G I L C G+P + W+ + PL GS + S+ +H +
Sbjct: 3033 AFSYLVEPVGGS-IQLDCV-VRGDPVPDIHWIKDGL-PLRGSHLRHQLQNGSLTIH--RT 3087
Query: 526 QEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-VSVLEGGEAWLECSLRGGTP 584
+ D AGR + C + + L L++ + EP+ ++V G + L C G
Sbjct: 3088 ERDDAGR-YQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPT 3146
Query: 585 PAQLLWLGPQQQKVDPGTSGFMLH--PEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSS 642
P + WL Q P + L P+G+ + D GTY CVA N +G+++
Sbjct: 3147 PT-IEWL----QAGQPLRASRRLRTLPDGSLWLENVETGDA----GTYDCVAHNLLGSAT 3197
Query: 643 QSVLLEVLRYP 653
L V P
Sbjct: 3198 ARAFLVVRGEP 3208
Score = 43.5 bits (101), Expect = 8e-04
Identities = 137/597 (22%), Positives = 206/597 (34%), Gaps = 127/597 (21%)
Query: 100 VSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSP 159
VS L LG+ G + C+ +V G + L L V VP PQ+ P
Sbjct: 1022 VSAVGRLLYLGQAQLAQEGTYTCECSNVVGN----SSQDLQLEVHVP---PQIAGPREPP 1074
Query: 160 VEGASVVATCAVRE----GTEPVTFAWQHRA-PRG--LGEALVGVTEPLFQLDPVNRTHL 212
+ + V A E G P T W+ P G LG L + L ++ H
Sbjct: 1075 TQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSL-HVERAQAAHT 1133
Query: 213 GWYMCSASNSVNRLSSDGAFLDVIYLATRTCYKKKSVSGIRLLDGAGLRRFKERGRMASY 272
G Y C A N L G R+F+
Sbjct: 1134 GRYSCVAEN---------------------------------LAGRAERKFE-------- 1152
Query: 273 LSVFTVAVCGNCELRTVEADGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSH 332
LSV P + + ++PL A+ +TL C A PP
Sbjct: 1153 LSVLV----------------PPELIGDLDPL----TNITAALHSPLTLLCEAMGIPPPA 1192
Query: 333 YVWLRDHTQVHTGP-TYVIA--------RAGRVHTGLYTCLARNSYLDTRTQTTVQLTIY 383
W R V G TY++A + +GLY+CLA N + R +V++ +
Sbjct: 1193 IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVP 1252
Query: 384 YPPEGQPSCAVHPSPEAVT--LLCAWPGGLPPAQLQW--EG-PQGPGPT---APSNVTWS 435
E + V + T L+C G P +L W +G P G +P V
Sbjct: 1253 PSIENEDLEEVIKVLDGQTAHLMCNVTGH-PQPKLTWFKDGRPLARGDAHHISPDGVLLQ 1311
Query: 436 HAAAQLPSGSVFTCTG--------QHPALAPPALCTVMLWEPLGRPTCWSTATMGDQFIM 487
A L S ++C +H L+ L +L T T+ + I
Sbjct: 1312 VLQANLSSAGHYSCIAANAVGEKTKHFQLSV-LLAPTILGGAEDSADEEVTVTVNNP-IS 1369
Query: 488 LSCEWPGGEPPATLGWLD-----EQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLL 542
L CE P + W+ E + + + + +L AQ++ AG ++TC T+ L
Sbjct: 1370 LICE-ALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAG-QYTCVVTNEL 1427
Query: 543 RTPDPHCHLQL--------EAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQ 594
+ H+++ + P +V V LEC PP + W
Sbjct: 1428 GEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECE-SWAVPPPTIRWY-KD 1485
Query: 595 QQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQ--SVLLEV 649
Q V P +S + EG L++ G Y CVA N G Q +VL++V
Sbjct: 1486 GQPVTP-SSRLQVLGEGRLLQI---QPTQVSDSGRYLCVATNVAGEDDQDFNVLIQV 1538
Score = 42.7 bits (99), Expect = 0.001
Identities = 58/220 (26%), Positives = 83/220 (37%), Gaps = 39/220 (17%)
Query: 455 ALAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGS 514
A +PPA +V LG + + L C W G P + W ++Q L G
Sbjct: 209 AFSPPAPPSV-----LGAGAAQEVLGLAGADVELQC-WTSGVPTPQVEWTKDRQPVLPGG 262
Query: 515 SSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHL------QLEAPQLDVAEP----- 563
LQ QED G+ G+H+ C Q QL V P
Sbjct: 263 PH------LQVQED--GQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWG 314
Query: 564 -----RVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGI 618
V+V+E L C RG P + W + + P ++ + G QL+LG
Sbjct: 315 SNETGEVAVMEDHLVQLLCEARG-VPTPNITWF--KDGALLPTSTKVVYTRGGRQLQLGR 371
Query: 619 YDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNV 658
+ A G Y C A NAVG + ++ L+V PP +
Sbjct: 372 AQSSDA---GVYTCKASNAVGAAEKATRLDVY---VPPTI 405
Score = 38.9 bits (89), Expect = 0.021
Identities = 89/415 (21%), Positives = 147/415 (35%), Gaps = 56/415 (13%)
Query: 297 PVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV 356
PVI + L EE + V+L C A NP WL++ P + G+V
Sbjct: 1651 PVILGDTEELVEE-VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQV 1709
Query: 357 ---------HTGLYTCLARNSYLDTRTQTTVQLTIYYPPE------GQPSCAVHPSPEAV 401
Y C+A N T+++ + PP Q + ++ S V
Sbjct: 1710 LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQV--PPRIAGLDLEQVTAILNSS---V 1764
Query: 402 TLLCAWPGGLPPAQLQWEGPQGPGP-----TAPSNVTWSHAAAQLPSGSVFTCTGQHPA- 455
+L C P ++ Q P T A+L ++TC + A
Sbjct: 1765 SLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAG 1824
Query: 456 ----------LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLD 505
L PPA P G P +GD+ + LSCE P + D
Sbjct: 1825 RDQKLVQLSVLVPPAFRQA----PRG-PQDAVLVRVGDKAV-LSCETDALPEPTVTWYKD 1878
Query: 506 EQQQPLGGSSSSMA----VHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQL--D 559
Q L + ++ + + +AQ G ++C+ +++ L ++ P +
Sbjct: 1879 GQPLVLAQRTQALRGGQRLEIQEAQVSDKGL-YSCKVSNVAGEAVRTFTLTVQVPPTFEN 1937
Query: 560 VAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIY 619
VS + G L C + G P + WL + G + G +L+L
Sbjct: 1938 PKTETVSQVAGSPLVLTCDV-SGVPAPTVTWLKDRMPVESSAVHGVV--SRGGRLQLSRL 1994
Query: 620 DADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQL 674
A GTY CVA N + + ++ VL P + ++R + +EV+L
Sbjct: 1995 QPAQA---GTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRL 2046
Score = 34.7 bits (78), Expect = 0.39
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 9/78 (11%)
Query: 582 GTPPAQLLWL-GPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGN 640
GTP Q+ W GP + + G G + EG+ + AD G Y+C A N VG+
Sbjct: 28 GTPKPQVTWRKGPSSEPLH-GQPGVAVLEEGSLFLASVSPADS----GDYECQATNEVGS 82
Query: 641 SSQSVLLEVLRYPAPPNV 658
+S+ L V PP++
Sbjct: 83 TSRRAKLVVY---VPPSI 97
Score = 33.9 bits (76), Expect = 0.66
Identities = 86/385 (22%), Positives = 131/385 (34%), Gaps = 47/385 (12%)
Query: 315 EREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV---------HTGLYTCLA 365
E L C + PP W R+ + G + + GRV + G Y+C A
Sbjct: 1573 ENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKA 1632
Query: 366 RNSYLDTRTQTTVQLTIYYPP-------EGQPSCAVHPSPEAVTLLCAWPGGLPP--AQL 416
N + +L + PP E V+ S V+L C G P + L
Sbjct: 1633 SNEVGEDWLH--YELLVLTPPVILGDTEELVEEVTVNAS-STVSLQCPALGNPVPTISWL 1689
Query: 417 QWEGPQGPGP---TAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP---L 470
Q P P P + A++ + + C ++ A + L T+ + P
Sbjct: 1690 QNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIA 1749
Query: 471 GRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSM-AVHLLQ---AQ 526
G TA + + L C+ P + D Q LG + H LQ A+
Sbjct: 1750 GLDLEQVTAILNSS-VSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRAR 1808
Query: 527 EDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-----VSVLEGGEAWLECSLRG 581
+G +TC + L + P PR V V G +A L C
Sbjct: 1809 LSDSGM-YTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCE-TD 1866
Query: 582 GTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNS 641
P + W Q V + + G Q RL I +A +G Y C N G +
Sbjct: 1867 ALPEPTVTWYKDGQPLVLAQRTQAL---RGGQ-RLEIQEAQ-VSDKGLYSCKVSNVAGEA 1921
Query: 642 SQSVLLEVLRYPA---PPNVTISRL 663
++ L V P P T+S++
Sbjct: 1922 VRTFTLTVQVPPTFENPKTETVSQV 1946
Score = 31.6 bits (70), Expect = 3.3
Identities = 51/201 (25%), Positives = 66/201 (32%), Gaps = 28/201 (13%)
Query: 34 PEAPVEEVVSVQGVRGGSVELACGSGPAPLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAI 93
P + + E ++V V SV L C S P VL + L PRP
Sbjct: 879 PPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRP-------------- 924
Query: 94 ASALGV-VSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQV 152
GV +S + L + GH+ C+ L+ AG + H L V V P
Sbjct: 925 ----GVHLSADKALLQVDRADVWDAGHYTCEALNQAG----RSEKHYNLNVWVAPVFPLR 976
Query: 153 RLSNPSPVEGASVVATCAVREGTEPVTFAW----QHRAPRGLGEALVGVTEPLFQLDPVN 208
+ EG +C R G +W Q G G V L L
Sbjct: 977 ESHTLTVREGHPTSLSCECR-GVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQ 1035
Query: 209 RTHLGWYMCSASNSVNRLSSD 229
G Y C SN V S D
Sbjct: 1036 LAQEGTYTCECSNVVGNSSQD 1056
>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
sapiens]
Length = 1386
Score = 68.9 bits (167), Expect = 2e-11
Identities = 104/483 (21%), Positives = 171/483 (35%), Gaps = 67/483 (13%)
Query: 317 EEVTLSCLAASNPPSHYV-WLRDHTQVHTGPTYVIARAGRV---HT-----GLYTCLARN 367
E L C+ P V W +D ++ + R G++ HT G+Y C+A N
Sbjct: 181 EPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASN 240
Query: 368 SYLDTRTQTTVQLTIYYPPE--GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPG 425
R ++ + P +P V + VT LC G PP +L+W G
Sbjct: 241 M-AGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGD-PPPRLRWRKEDGEL 298
Query: 426 PTAPSNVTWSHAA----AQLPSGSVFTCTGQHPALAPPALCTVMLWEP---LGRPTCWST 478
PT + H+ +TC ++ A ++ + P + +P
Sbjct: 299 PTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMA 358
Query: 479 ATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMA------------VHLLQAQ 526
A + + CE G PPA W E Q L S S+ +++ Q
Sbjct: 359 AP--GESVAFQCETKGNPPPAIF-WQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQ 415
Query: 527 EDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRV-------SVLEGGEAWLECSL 579
AG + C+ + + L+++ LD P + +++ G WL C +
Sbjct: 416 RGDAGY-YVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRV 474
Query: 580 RGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVG 639
G P+ + W Q + F G + + D G Y CVA+++ G
Sbjct: 475 TGNPQPS-VRWK-KDGQWLQGDDLQFKTMANGTLYIANVQEMD----MGFYSCVAKSSTG 528
Query: 640 NSSQSVLLEV-----------LRYPAPPNVTISRLTYGRHRREVQLQWAILGPGNLTGFL 688
++ S L++ +PP + + + L W P TG
Sbjct: 529 EATWSGWLKMREDWGVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWK---PNPQTGAA 585
Query: 689 VQRKA-SALGPGAG-AWETAASDIEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPSEV 746
V A P AG W T A ++ E+ + GL P +Y F + A+ PS V
Sbjct: 586 VTSYVIEAFSPAAGNTWRTVADGVQLETH--TVSGLQPNTIYLFLVRAVGAWGLSEPSPV 643
Query: 747 KIP 749
P
Sbjct: 644 SEP 646
Score = 59.7 bits (143), Expect = 1e-08
Identities = 92/378 (24%), Positives = 132/378 (34%), Gaps = 54/378 (14%)
Query: 314 SEREEVTLSCLAASNPPSHYVWLRDHTQVHTG------------------PTYVIARAGR 355
S E TL C A P + W ++ +V T P V R R
Sbjct: 76 SRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRAR 135
Query: 356 VHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEG---QPSCAVHPSPEAVTLLCAWPGGLP 412
G+YTC+ARN YL L + + P V E L C P G P
Sbjct: 136 PDEGVYTCVARN-YLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHP 194
Query: 413 PAQLQW-------EGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPA-LAPPALCTV 464
+ W + +G + SH ++ C + A A V
Sbjct: 195 EPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKS--DAGMYVCVASNMAGERESAAAEV 252
Query: 465 MLWEP---LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVH 521
M+ E L RP + + D + CE G+PP L W E + G + H
Sbjct: 253 MVLERPSFLRRPV--NQVVLADAPVTFLCE-VKGDPPPRLRWRKEDGELPTGRYEIRSDH 309
Query: 522 LLQAQEDLAGRE--FTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEA-WLECS 578
L A E +TC + + + L + P V +P+ + GE+ +C
Sbjct: 310 SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCE 369
Query: 579 LRGGTPPAQLLWL--GPQ-----QQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQ 631
+G PPA + W G Q Q + P T F + P G QL + A G Y
Sbjct: 370 TKGNPPPA-IFWQKEGSQVLLFPSQSLQP-TGRFSVSPRG-QLNITAVQRGDA---GYYV 423
Query: 632 CVARNAVGNSSQSVLLEV 649
C A + G+ LLE+
Sbjct: 424 CQAVSVAGSILAKALLEI 441
Score = 35.8 bits (81), Expect = 0.17
Identities = 77/356 (21%), Positives = 126/356 (35%), Gaps = 71/356 (19%)
Query: 389 QPSCAVHPSPEAVTLLCAWPGGLPPAQLQW-----------EGPQGPGPTAPSNVTWS-- 435
QP + E TL C G P ++W E P+ PS +
Sbjct: 69 QPPDLLVSRGEPATLPCR-AEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPR 127
Query: 436 --HAAAQLPSGSVFTCTGQH---PALAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSC 490
H P V+TC ++ A + A V + R + + + +L C
Sbjct: 128 IVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLEC 187
Query: 491 EWPGGEPPATLGW------LDEQQQPL---GGS-------SSSMAVHLLQAQEDLAGREF 534
P G P ++ W L E++ + GG S +++ A RE
Sbjct: 188 VPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASNMAGERES 247
Query: 535 TCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQ 594
+L P L+ Q+ +A+ V+ L C ++G PP +L W +
Sbjct: 248 AAAEVMVLERPS---FLRRPVNQVVLADAPVTFL--------CEVKGDPPP-RLRW---R 292
Query: 595 QQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPA 654
++ + T + + + + L +G A+ GTY CVA N+VG + S L V
Sbjct: 293 KEDGELPTGRYEIRSDHS-LWIGHVSAED---EGTYTCVAENSVGRAEASGSLSV---HV 345
Query: 655 PPNVTISRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDI 710
PP + Q Q + PG F + K + P A W+ S +
Sbjct: 346 PPQLV------------TQPQDQMAAPGESVAFQCETKGNP--PPAIFWQKEGSQV 387
Score = 35.4 bits (80), Expect = 0.23
Identities = 49/187 (26%), Positives = 75/187 (40%), Gaps = 24/187 (12%)
Query: 50 GSVELACGSGPAPLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVL 109
G+V +A G PA VL P G P DGA K E G +++R L++
Sbjct: 173 GNVVVAVGE-PA---VLECVPPRGHPEPSVSWRKDGARLKEEE-----GRITIRGGKLMM 223
Query: 110 GELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQV--RLSNPSPVEGASVVA 167
+ G ++C ++AG + AA A ++ + +P R N + A V
Sbjct: 224 SHTLKSDAGMYVCVASNMAGERESAA------AEVMVLERPSFLRRPVNQVVLADAPVTF 277
Query: 168 TCAVREGTEPVTFAWQHR---APRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVN 224
C V+ G P W+ P G E ++ + V+ G Y C A NSV
Sbjct: 278 LCEVK-GDPPPRLRWRKEDGELPTGRYEIR---SDHSLWIGHVSAEDEGTYTCVAENSVG 333
Query: 225 RLSSDGA 231
R + G+
Sbjct: 334 RAEASGS 340
Score = 32.0 bits (71), Expect = 2.5
Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 112 LHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSP---VEGASVVAT 168
+ G G+++CQ + VAG L A + A L + P V L P+ V G+SV
Sbjct: 414 VQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGL--PPVILQGPANQTLVLGSSVWLP 471
Query: 169 CAVREGTEPVTFAWQHRAPRGLGEALVGVT--EPLFQLDPVNRTHLGWYMCSASNSVNRL 226
C V +P + W+ G+ L T + V +G+Y C A +S
Sbjct: 472 CRVTGNPQP-SVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEA 530
Query: 227 SSDG 230
+ G
Sbjct: 531 TWSG 534
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 68.6 bits (166), Expect = 2e-11
Identities = 97/372 (26%), Positives = 144/372 (38%), Gaps = 53/372 (14%)
Query: 319 VTLSCLAASNPPSHYVWLRDHTQVHTG--PTYVIARAGRVHT---------GLYTCLARN 367
V L+C A P +WL+D V P + GRV T G Y+C+A +
Sbjct: 1995 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 2054
Query: 368 SYLDTRTQTTVQLTIYYPPE--GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPG 425
+ + R +Q ++ PP G+ + E+V L C PP W+ +
Sbjct: 2055 AVGEDRQDVVLQ--VHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLE 2112
Query: 426 PTAPSNVTWSHAAAQLPSGSV-----FTCTGQHPALAPPALCTVMLWEPLGRPTCWS-TA 479
P +++ A Q+ V +TC + A + +W P S T
Sbjct: 2113 PRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTL 2172
Query: 480 TMGDQF-IMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMA--------VHLLQAQEDLA 530
T+ + LSCE G P + W + Q PL G + + ++L QAQ
Sbjct: 2173 TVREGHPTSLSCECRG-VPFPKISWRKDGQ-PLPGEGAGLQHVSAVGRLLYLGQAQLAQE 2230
Query: 531 GREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-----VSVLEGGEAWLECSLRGGTPP 585
G +TC ++++ L++ P +A PR VSV++ G A LEC+ G PP
Sbjct: 2231 GT-YTCECSNVVGNSSQDLQLEVHVPP-QIAGPREPPTQVSVVQDGVATLECNATGKPPP 2288
Query: 586 AQLLWLGPQQQKVDPG----TSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNS 641
Q + G G LH E AQ A H G Y CVA N G +
Sbjct: 2289 TVTWERDGQPVGAELGLQLQNQGQSLHVERAQ----------AAHTGRYSCVAENLAGRA 2338
Query: 642 SQSVLLEVLRYP 653
+ L VL P
Sbjct: 2339 ERKFELSVLVPP 2350
Score = 67.4 bits (163), Expect = 5e-11
Identities = 90/398 (22%), Positives = 149/398 (37%), Gaps = 69/398 (17%)
Query: 295 DKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVH----------- 343
+ P I P LT + L C A+ +P VW +D ++
Sbjct: 3762 EPPAIAPSPSNLT-----LTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLL 3816
Query: 344 TGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTL 403
++ G + + C+ N + Q+T++ PP + A + VT+
Sbjct: 3817 PSNALLLTAPGPQDSAQFECVVSNEVGEAHR--LYQVTVHVPP----TIADDQTDFTVTM 3870
Query: 404 LCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQL----------PSGSV------- 446
+ P L P PT V+WS A AQL PSG++
Sbjct: 3871 MA-------PVVLTCHSTGIPAPT----VSWSKAGAQLGARGSGYRVSPSGALEIGQALP 3919
Query: 447 -----FTCTGQHPA-LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPAT 500
+TC+ ++ A +A + + P+ +P + ++ ++L CE G P T
Sbjct: 3920 IHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 3978
Query: 501 LGWLDEQQQPLGGSSSSMA----VHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAP 556
+ W E G S+ + + + A + AG + C + + L ++ P
Sbjct: 3979 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGN-YLCIAKNSAGSAMGKTRLVVQVP 4037
Query: 557 Q-LDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLR 615
++ P +S EG A+L C RG +P + W Q V F + P G L
Sbjct: 4038 PVIENGLPDLSTTEGSHAFLPCKARG-SPEPNITW-DKDGQPVSGAEGKFTIQPSGELLV 4095
Query: 616 LGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYP 653
+ D GTY C A NAVG + + V L +L P
Sbjct: 4096 KNLEGQDA----GTYTCTAENAVGRARRRVHLTILVLP 4129
Score = 67.0 bits (162), Expect = 7e-11
Identities = 94/374 (25%), Positives = 136/374 (36%), Gaps = 44/374 (11%)
Query: 315 EREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV---------HTGLYTCLA 365
E VTL CLA+ PP W + H V + ++ GRV G Y C+A
Sbjct: 1899 ENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVA 1958
Query: 366 RNSYLDTRTQTTVQLTIYYPPE-----GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQW-- 418
N + T+ L + PP P + +P V L C G P L W
Sbjct: 1959 SN--VAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTP--VRLTCN-ATGAPSPTLMWLK 2013
Query: 419 -EGPQGPGPTA-----PSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP--- 469
P P T P + A+A+ ++C + + P
Sbjct: 2014 DGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSI 2073
Query: 470 LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQ-QPLGGSSSSMAVHLLQAQ-- 526
LG + + + ++ + L C+ PP W D + +P G S LLQ
Sbjct: 2074 LGEEL--NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRA 2131
Query: 527 EDLAGREFTCRGTHLLRTPDPHCHLQL-EAPQLDVAEPR-VSVLEGGEAWLECSLRGGTP 584
+ +TC + + H +L + AP + E ++V EG L C R G P
Sbjct: 2132 DVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECR-GVP 2190
Query: 585 PAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQS 644
++ W Q PG + H L + A A GTY C N VGNSSQ
Sbjct: 2191 FPKISWRKDGQPL--PGEGAGLQHVSAVGRLLYLGQAQLA-QEGTYTCECSNVVGNSSQD 2247
Query: 645 VLLEVLRYPAPPNV 658
+ LEV PP +
Sbjct: 2248 LQLEV---HVPPQI 2258
Score = 65.9 bits (159), Expect = 2e-10
Identities = 100/377 (26%), Positives = 144/377 (38%), Gaps = 50/377 (13%)
Query: 314 SEREEVTLSCLAASNPPSHYVW------LRDHTQVHTGP--TYVIARAGRVHTGLYTCLA 365
S+ EV +SC A+ P H W L++ +++H T +I G Y+C A
Sbjct: 620 SQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA 679
Query: 366 RNSYLDTRTQTTVQLTIYY--PPEGQPSCAVH--PSPEAVTLLCAWPGGLPPAQLQWEGP 421
N + T +T +T+YY PP AV E L+C G PP + + G
Sbjct: 680 TNE-VGTDQET---VTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGG 735
Query: 422 QGP--GPTAPSNVTWSHAAAQLPSGSVFTCT-----GQHPALAPPALCTVMLWEPLGRPT 474
P S+ AAQ +TC G A A+ L R
Sbjct: 736 LEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDV 795
Query: 475 CWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLG-------GSSSSMAVHLLQAQE 527
T +G + +L+C G PP T+ W QPLG GS S + E
Sbjct: 796 ---TVELG-RSALLACR-ATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFE 850
Query: 528 DLAGRE---FTCRGTHLLRTPDPHCHLQLEA---PQLDVAEPRVSVLEGGEAWLECSLRG 581
+A + + C ++ L + PQ+ + P V VLEG L C +
Sbjct: 851 SVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLA 910
Query: 582 GTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNS 641
G P + WL + + PG S + +G+ L L D H G Y CVA N G+
Sbjct: 911 GRPLPERHWL-KDGRPLPPG-SRHSIRADGS-LHL---DRALQEHAGRYSCVATNTAGSQ 964
Query: 642 SQSVLLEVLRYPAPPNV 658
+ V L V PP +
Sbjct: 965 HRDVELVV---QVPPRI 978
Score = 65.5 bits (158), Expect = 2e-10
Identities = 115/473 (24%), Positives = 176/473 (37%), Gaps = 111/473 (23%)
Query: 256 DGAGLRRFKERGRMASYLSVFTVAVCGN--CELRTV----------EADGPDKPVITMEP 303
+GAGL+ GR+ YL +A G CE V E P + EP
Sbjct: 2206 EGAGLQHVSAVGRLL-YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREP 2264
Query: 304 ---LGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQV---------HTGPTYVIA 351
+ + ++G TL C A PP W RD V + G + +
Sbjct: 2265 PTQVSVVQDGV-------ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVE 2317
Query: 352 RAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPE--------GQPSCAVHPSPEAVTL 403
RA HTG Y+C+A N L R + +L++ PPE + A+H SP +TL
Sbjct: 2318 RAQAAHTGRYSCVAEN--LAGRAERKFELSVLVPPELIGDLDPLTNITAALH-SP--LTL 2372
Query: 404 LCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAA--------QLPSGSVFTCTGQHPA 455
LC G+PP ++W +G P +P T+ A Q +++C + A
Sbjct: 2373 LCE-AMGIPPPAIRWF--RGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 2429
Query: 456 -----------LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWL 504
L PP++ L E + + Q L C G P L W
Sbjct: 2430 GEARRNFSVEVLVPPSIENEDLEEVI--------KVLDGQTAHLMCNVTG-HPQPKLTWF 2480
Query: 505 DEQQQPLGG-----SSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQ-LEAPQL 558
+ + G S + + +LQA AG ++C + + H L L AP +
Sbjct: 2481 KDGRPLARGDAHHISPDGVLLQVLQANLSSAGH-YSCIAANAVGEKTKHFQLSVLLAPTI 2539
Query: 559 -----DVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWL-------GPQQQKVDPGTSGFM 606
D A+ V+V L C P + W+ + ++ PGT G
Sbjct: 2540 LGGAEDSADEEVTVTVNNPISLICEALA-FPSPNITWMKDGAPFEASRNIQLLPGTHGLQ 2598
Query: 607 LHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVT 659
+ L DA G Y CV N +G + ++ +EVL PP+++
Sbjct: 2599 I------LNAQKEDA------GQYTCVVTNELGEAVKNYHVEVL---IPPSIS 2636
Score = 61.2 bits (147), Expect = 4e-09
Identities = 139/605 (22%), Positives = 211/605 (34%), Gaps = 105/605 (17%)
Query: 127 VAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTFAWQHRA 186
VA Q +A TL V VP + L + + +SV C V P ++
Sbjct: 2917 VAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ 2976
Query: 187 PRGLGEA--LVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLATRTCY 244
LGE L+ T L QL + G Y C A N+ R ++ A R
Sbjct: 2977 ALSLGEEVFLLPGTHTL-QLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAP 3035
Query: 245 K-KKSVSGIRLLDGAGLRRFKE----------RGRMASYLSVFTVAVCGNCELRTVEADG 293
+ + +R+ D A L + + L+ T A+ G L EA
Sbjct: 3036 RGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQV 3095
Query: 294 PDKPVITMEPLGLTEEG-------------FWASEREEVT--------LSCLAASNPPSH 332
DK + + + + E F + E V+ L+C + P
Sbjct: 3096 SDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT 3155
Query: 333 YVWLRDHTQVHTGPTY-VIARAGRVH--------TGLYTCLARNSYLDTRTQTTVQLTIY 383
WL+D V + + V++R GR+ G YTC+A N+ + R V + +
Sbjct: 3156 VTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVA 3215
Query: 384 YPPEGQPSCAVHPSPEA--VTLLCAWPGGLPPAQLQWEGPQGP-----GPTAPSNVTWSH 436
H E V L C G PP + W P GP H
Sbjct: 3216 PRIRSSGVAREHHVLEGQEVRLDCE-ADGQPPPDVAWLKDGSPLGQDMGP---------H 3265
Query: 437 AAAQLPSGSV------------FTCTGQHPALAPPALCTVMLWEP----LGRPTCWSTAT 480
L GS+ +TC +PA L TV + P G + +
Sbjct: 3266 LRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVS 3325
Query: 481 MGDQFIMLSCEWPGGEPPATLGWLDE-------QQQPLGGSSSSMAVHLLQAQEDLAGRE 533
+ + + C G PP + WL + Q+ L GS ++ + +Q + AG
Sbjct: 3326 RPGELVTMVCP-VRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLAD--AG-I 3381
Query: 534 FTCRGTHLLRTPDPHCHLQLEAPQLDVAEP-----RVSVLEGGEAWLECSLRGGTPPAQL 588
FTC D + LQ++ P V EP V V+ G L C R G P +
Sbjct: 3382 FTCVAASPAGVADRNFTLQVQVP--PVLEPVEFQNDVVVVRGSLVELPCEAR-GVPLPLV 3438
Query: 589 LWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLE 648
W+ + + +G L+L +A A GTY CVA + G + + L
Sbjct: 3439 SWMKDGEPLLSQSLE------QGPSLQL---EAVGAGDSGTYSCVAVSEAGEARRHFQLT 3489
Query: 649 VLRYP 653
V+ P
Sbjct: 3490 VMEPP 3494
Score = 60.5 bits (145), Expect = 7e-09
Identities = 87/367 (23%), Positives = 139/367 (37%), Gaps = 32/367 (8%)
Query: 319 VTLSCLAASNPPSHYVWLRD-----HTQVHTGPTYVIARAGRVHTGLYTCLARNSYLDTR 373
V L C A P W++D + GP+ + G +G Y+C+A + + R
Sbjct: 3424 VELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 3483
Query: 374 TQTTVQLTIYYPPE----GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAP 429
QLT+ PP GQP+ + LLC G P + W G T
Sbjct: 3484 RH--FQLTVMEPPHIEDSGQPTELSLTPGAPMELLCD-AQGTPQPNITWH-KDGQALTRL 3539
Query: 430 SNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP---LGRPTCWSTATMGDQFI 486
N + + ++ ++TC + PA A V + P +G + +
Sbjct: 3540 ENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL 3599
Query: 487 MLSCEWPGGEPPATLGWLDE----QQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLL 542
+L C EP + W + Q+ LQA +++C +
Sbjct: 3600 VLECSVEA-EPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAA 3658
Query: 543 RTPDPHCHLQLEA-PQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPG 601
+ +++ P + P V+V A L C G PA L+ + +DP
Sbjct: 3659 GSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADG--VPAPLVSWRKDRVPLDPR 3716
Query: 602 TSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPA----PPN 657
+ F + PEG+ LR+ A A H Y C+A N+ G+ Q L VL PA P N
Sbjct: 3717 SPRFEILPEGS-LRIQPVLAQDAGH---YLCLASNSAGSDRQGRDLRVLEPPAIAPSPSN 3772
Query: 658 VTISRLT 664
+T++ T
Sbjct: 3773 LTLTAHT 3779
Score = 60.1 bits (144), Expect = 9e-09
Identities = 141/622 (22%), Positives = 224/622 (36%), Gaps = 91/622 (14%)
Query: 107 LVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVV 166
L + E +G + C+V +VAG A TL V VP + + S V G+ +V
Sbjct: 3088 LEIQEAQVSDKGLYSCKVSNVAG----EAVRTFTLTVQVPPTFENPKTETVSQVAGSPLV 3143
Query: 167 ATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEP--LFQLDPVNRTHLGWYMCSASNS-- 222
TC V G T W A+ GV QL + G Y C A N+
Sbjct: 3144 LTCDV-SGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQA 3202
Query: 223 ------------VNRLSSDGAFLDVIYLATRTCYKKKSVSGIRLLDGAGLRRFKERGR-- 268
R+ S G + L + G D A L+ G+
Sbjct: 3203 EARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM 3262
Query: 269 ---MASYLSVFTVAVCGNCELRTVEAD----------GPDKPVITMEPL-------GLTE 308
+ YL ++ + G LR +A G D + T+ L G
Sbjct: 3263 GPHLRFYLDGGSLVLKG---LRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADG 3319
Query: 309 EGFWASEREE-VTLSCLAASNPPSHYVWLRD--------HTQVH-TGPTYVIARAGRVHT 358
G S E VT+ C +PP H WL+D T +H +G T I++
Sbjct: 3320 SGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADA 3379
Query: 359 GLYTCLARNSYLDTRTQTTVQLTIYYPPEGQP----SCAVHPSPEAVTLLCAWPGGLPPA 414
G++TC+A + T+Q+ + PP +P + V V L C G+P
Sbjct: 3380 GIFTCVAASPAGVADRNFTLQVQV--PPVLEPVEFQNDVVVVRGSLVELPCE-ARGVPLP 3436
Query: 415 QLQW--EGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP--- 469
+ W +G + + A ++C A + + EP
Sbjct: 3437 LVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHI 3496
Query: 470 --LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQE 527
G+PT S ++ + G P + W + Q ++S A +L+ ++
Sbjct: 3497 EDSGQPTELSLTPGAPMELLCDAQ---GTPQPNITWHKDGQALTRLENNSRATRVLRVRD 3553
Query: 528 DLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR----VSVLEGGEAWLECSLRGGT 583
AG +TC + ++++AP ++ PR V L G+ LECS+
Sbjct: 3554 --AGL-YTCLAESPAGAIEKSFRVRVQAPP-NIVGPRGPRFVVGLAPGQLVLECSVEA-E 3608
Query: 584 PPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQ 643
P ++ W + + F QL+ + AD G Y C ARNA G++S
Sbjct: 3609 PAPKITWHRDGIVLQEDAHTQFPERGRFLQLQ-ALSTADS----GDYSCTARNAAGSTSV 3663
Query: 644 SVLLEVLRYP----APPNVTIS 661
+ +E+ P PP V +S
Sbjct: 3664 AFRVEIHTVPTIRSGPPAVNVS 3685
Score = 55.8 bits (133), Expect = 2e-07
Identities = 79/337 (23%), Positives = 122/337 (36%), Gaps = 26/337 (7%)
Query: 339 HTQVHTGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSP 398
H Q ++ I RA + G Y C A + R + + +T PP+ P+ V SP
Sbjct: 472 HFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVT-DPPPQLVPAPNVTVSP 530
Query: 399 EAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAP 458
+L G P L W P + V + SG + T G++ +A
Sbjct: 531 GETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVAS 590
Query: 459 PA--LCTVMLWEPLGRPTCWSTATMGDQF-----IMLSCEWPGGEPPATLGWLDEQQQPL 511
A + +W + S T F + +SC G P + W E Q
Sbjct: 591 NANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCS-ASGYPTPHISWSRESQALQ 649
Query: 512 GGSS---SSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHL-QLEAPQLDVAEPRVSV 567
S + ++Q ++C+ T+ + T L + P + V V
Sbjct: 650 EDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLV 709
Query: 568 LEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHR 627
G EA L C G PP +++W G +L PEG+ A
Sbjct: 710 AVGEEAVLVCE-ASGVPPPRVIWY--------RGGLEMILAPEGSSSGKLRIPAAQERDA 760
Query: 628 GTYQCVARNAVGNSSQSVLLEVLRYP----APPNVTI 660
GTY C A N +G++S + L V P P +VT+
Sbjct: 761 GTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTV 797
Score = 55.1 bits (131), Expect = 3e-07
Identities = 90/391 (23%), Positives = 142/391 (36%), Gaps = 55/391 (14%)
Query: 305 GLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGP---------TYVIARAGR 355
GL E A V+L C ++P W +D + G T + RA
Sbjct: 2941 GLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARL 3000
Query: 356 VHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQ-----PSCAVHPSPEAVTLLCAWPGG 410
+G+YTC A N+ R Q VQL++ PP + P AV +L
Sbjct: 3001 SDSGMYTCEALNA--AGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDA 3058
Query: 411 LPPAQLQWEGPQGPGPTAPSNVTWSHA------AAQLPSGSVFTCTGQHPALAPPALCTV 464
LP + W P A AQ+ +++C + A T+
Sbjct: 3059 LPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTL 3118
Query: 465 MLWEP--LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHL 522
+ P P + + + ++L+C+ G P T+ WL ++ S AVH
Sbjct: 3119 TVQVPPTFENPKTETVSQVAGSPLVLTCD-VSGVPAPTVTWLKDRM-----PVESSAVHG 3172
Query: 523 LQAQE---DLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRV---------SVLEG 570
+ ++ L+ + GT+ + + + + PR+ VLEG
Sbjct: 3173 VVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEG 3232
Query: 571 GEAWLECSLRGGTPPAQLLWL---GPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHR 627
E L+C G PP + WL P Q + P ++ +G L L A A
Sbjct: 3233 QEVRLDCE-ADGQPPPDVAWLKDGSPLGQDMGPHLRFYL---DGGSLVLKGLRASDA--- 3285
Query: 628 GTYQCVARNAVGNSSQSVLLEVLRYPAPPNV 658
G Y CVA N G ++ + VL PP +
Sbjct: 3286 GAYTCVAHNPAGEDARLHTVNVL---VPPTI 3313
Score = 54.7 bits (130), Expect = 4e-07
Identities = 96/392 (24%), Positives = 137/392 (34%), Gaps = 75/392 (19%)
Query: 319 VTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGR---------VHTGLYTCLARNSY 369
V L C A P + W +D + T V R GR G+YTC A N+
Sbjct: 1520 VQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAV 1579
Query: 370 LDTRTQTTVQLTIYYPPE-----GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQW--EGPQ 422
+ +L +Y PP G+P + V L C G P L W EG
Sbjct: 1580 --GAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECV-ARGHPSPTLSWHHEGL- 1635
Query: 423 GPGPTAPSNVTWSHAAAQL--------PSGSVFTCTGQHPA-----------LAPPALCT 463
P A SN + + S +++C PA PP L
Sbjct: 1636 ---PVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQL-- 1690
Query: 464 VMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQ--QPLGG---SSSSM 518
++ E LG+ T T+ Q + L C+ G P T+ WL + + L G +S
Sbjct: 1691 -LVAEGLGQVT-----TIVGQPLELPCQ-ASGSPVPTIQWLQNGRPAEELAGVQVASQGT 1743
Query: 519 AVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLE---APQLDVAEPRVSVLEGGEAWL 575
+H+ + D +G F C+ T+ T + + AP V E + G
Sbjct: 1744 TLHIDHVELDHSGL-FACQATNEAGTAGAEVEVSVHGEWAP--GVLEVPIGQYHWGXEHH 1800
Query: 576 ECSLRGGTPPAQLLW-LGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADP--------AHH 626
PP W P+ V+ S L E + + Y P
Sbjct: 1801 SSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVA-YSLPPPLQIEKVDLRD 1859
Query: 627 RGTYQCVARNAVGNSSQSVLLEVLRYPAPPNV 658
G Y C A N G S + V L+VL PPN+
Sbjct: 1860 EGIYTCAATNLAGESKREVALKVL---VPPNI 1888
Score = 53.1 bits (126), Expect = 1e-06
Identities = 134/617 (21%), Positives = 219/617 (35%), Gaps = 106/617 (17%)
Query: 118 GHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLS--NPSPVEGASVVATCAVREGT 175
G + C ++AG + + L VLVP P + N + +E ASV C + G
Sbjct: 1861 GIYTCAATNLAG----ESKREVALKVLVP---PNIEPGPVNKAVLENASVTLEC-LASGV 1912
Query: 176 EPVTFAW--QHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVN--------- 224
P +W H+ V V + +++ + G Y C ASN
Sbjct: 1913 PPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLR 1972
Query: 225 -----RLSSDGAFLDVIYLATR---TCYKKKSVSG--IRLLDG--------AGLRRFKER 266
R++ + + + T TC + S + L DG GL+ F
Sbjct: 1973 VNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPG- 2031
Query: 267 GRMASYLSVFTVAVCGNCELRTVEADGPDKPVITME----PLGLTEE-GFWASEREEVTL 321
GR+ + S + G V A G D+ + ++ P L EE E V L
Sbjct: 2032 GRVLTLASA-RASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVAL 2090
Query: 322 SCLAASNPPSHYVWLRDHTQVHTGPTYVIA---------RAGRVHTGLYTCLARNS--YL 370
C + + PP W +D + P ++ RA G YTC A N +
Sbjct: 2091 ECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHS 2150
Query: 371 DTRTQTTVQLTIYYPPEGQPSCAVHPS-PEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAP 429
+ V + +P + V P +++ C G+P ++ W P P
Sbjct: 2151 EKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECR---GVPFPKISWRKDGQPLPGEG 2207
Query: 430 SNVTWSHAA--------AQLPSGSVFTCTG-----------QHPALAPPALCTVMLWEPL 470
+ + A AQL +TC Q PP + P
Sbjct: 2208 AGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAG-----PR 2262
Query: 471 GRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGS------SSSMAVHLLQ 524
PT + + D L C G+PP T+ W + QP+G + ++H+ +
Sbjct: 2263 EPPT--QVSVVQDGVATLECN-ATGKPPPTVTW-ERDGQPVGAELGLQLQNQGQSLHVER 2318
Query: 525 AQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAE----PRVSVLEGGEAWLECSLR 580
AQ GR ++C +L + L + P + + ++ L C
Sbjct: 2319 AQAAHTGR-YSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAM 2377
Query: 581 GGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGN 640
G PPA + G ++ V PG ++L G L++ G Y C+A N G
Sbjct: 2378 GIPPPAIRWFRG--EEPVSPGEDTYLL-AGGWMLKM---TQTQEQDSGLYSCLASNEAGE 2431
Query: 641 SSQSVLLEVLRYPAPPN 657
+ ++ +EVL P+ N
Sbjct: 2432 ARRNFSVEVLVPPSIEN 2448
Score = 50.8 bits (120), Expect = 5e-06
Identities = 87/354 (24%), Positives = 132/354 (37%), Gaps = 61/354 (17%)
Query: 315 EREEVTLSCLA-ASNPPSHYVWLRDHTQVHTGPTYVIA--------RAGRVHTGLYTCLA 365
E + V+L C+ A P WL+D + G + I RA + H G Y+C+A
Sbjct: 898 EGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVA 957
Query: 366 RNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPG 425
N+ V+L + PP P+ H + E V PA L P
Sbjct: 958 TNTAGSQHRD--VELVVQVPPRIHPTATHHITNEGV-----------PASLPCVASGVPA 1004
Query: 426 PTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP----LGRPTCWSTATM 481
PT +TW+ L T G H ++ T+++ +P G C +T T+
Sbjct: 1005 PT----ITWTKETNAL------TSRGPHYNVSKEG--TLLIAQPSAQDAGAYVCTATNTV 1052
Query: 482 G--DQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGT 539
G Q + LS A ++ E+ G S ++ L Q Q +G + C +
Sbjct: 1053 GFSSQEMRLSVN-----RLALSKYVWEEY----GLLPSGSLRLAQVQVGDSGH-YECTAS 1102
Query: 540 HLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVD 599
+ + L ++ P PRV + GEA + G P QL W
Sbjct: 1103 NPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSW--------- 1153
Query: 600 PGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYP 653
G +L G Q + + A G Y+C A N+ G + V L VL P
Sbjct: 1154 -SKDGVVLQGRGPQGSVH-FAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPP 1205
Score = 48.5 bits (114), Expect = 3e-05
Identities = 87/396 (21%), Positives = 140/396 (35%), Gaps = 75/396 (18%)
Query: 317 EEVTLSCLAASNPPSHYVWLRDHTQ--VHTGPTYVIARAGRVH--------TGLYTCLAR 366
E +L C A P W + + +H P + G + +G Y C A
Sbjct: 1222 ENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQAT 1281
Query: 367 NSYLDTRTQTTVQLTIYYPP----EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQW-EGP 421
N T + +L +Y PP +G+ + + +++TL C G P ++ W +
Sbjct: 1282 NEVGSTSRRA--KLVVYVPPSIREDGRKANVSGMAGQSLTLECD-ANGFPVPEIVWLKDA 1338
Query: 422 QGPG-PTAPSNVTWSHAAAQLPS-------------------GSVFTCTGQHPALAPPAL 461
Q G P + W Q+ +++C ++ A
Sbjct: 1339 QLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRD 1398
Query: 462 CTVMLWEP---LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSM 518
+++ P LG + + L C W G P + W ++Q L G
Sbjct: 1399 FHLLVLTPPSVLGAGAAQEVLGLAGADVELQC-WTSGVPTPQVEWTKDRQPVLPGGPH-- 1455
Query: 519 AVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHL------QLEAPQLDVAEP--------- 563
LQ QED G+ G+H+ C Q QL V P
Sbjct: 1456 ----LQVQED--GQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNET 1509
Query: 564 -RVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDAD 622
V+V+E L C RG P + W + + P ++ + G QL+LG +
Sbjct: 1510 GEVAVMEDHLVQLLCEARG-VPTPNITWF--KDGALLPTSTKVVYTRGGRQLQLGRAQSS 1566
Query: 623 PAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNV 658
A G Y C A NAVG + ++ L+V PP +
Sbjct: 1567 DA---GVYTCKASNAVGAAEKATRLDVY---VPPTI 1596
Score = 48.5 bits (114), Expect = 3e-05
Identities = 88/380 (23%), Positives = 141/380 (37%), Gaps = 59/380 (15%)
Query: 315 EREEVTLSCLAASNPPSHYVWLRDHTQVH-----------TGPTYVIARAGRVHTGLYTC 363
E +LSC P W +D + G + +A G YTC
Sbjct: 2176 EGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTC 2235
Query: 364 LARNSYLDTRTQTTVQLTIYYPPE----GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWE 419
N + + +QL ++ PP+ +P V + V L G PP + WE
Sbjct: 2236 ECSN--VVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWE 2293
Query: 420 GPQGP-----GPTAPSNVTWSHAA-AQLPSGSVFTCTGQHPA-----------LAPPALC 462
P G + H AQ ++C ++ A L PP L
Sbjct: 2294 RDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELI 2353
Query: 463 TVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMA--- 519
+ +PL TA + +L CE G PPA + E+ G + +A
Sbjct: 2354 GDL--DPLTN----ITAALHSPLTLL-CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGW 2406
Query: 520 -VHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAP---QLDVAEPRVSVLEGGEAWL 575
+ + Q QE +G ++C ++ + +++ P + + E + VL+G A L
Sbjct: 2407 MLKMTQTQEQDSGL-YSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHL 2465
Query: 576 ECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLH--PEGAQLRLGIYDADPAHHRGTYQCV 633
C++ G P +L W + P G H P+G L++ + A H Y C+
Sbjct: 2466 MCNVTGHPQP-KLTWFKDGR----PLARGDAHHISPDGVLLQVLQANLSSAGH---YSCI 2517
Query: 634 ARNAVGNSSQSVLLEVLRYP 653
A NAVG ++ L VL P
Sbjct: 2518 AANAVGEKTKHFQLSVLLAP 2537
Score = 48.1 bits (113), Expect = 3e-05
Identities = 165/696 (23%), Positives = 228/696 (32%), Gaps = 137/696 (19%)
Query: 37 PVEEVVSVQGVRGGSVELACGSGPAPL-LVLWSFTPLGSLVPRPVAVTDGAMSKVEAIAS 95
PVE V VRG VEL C + PL LV W + DG +++
Sbjct: 3409 PVEFQNDVVVVRGSLVELPCEARGVPLPLVSW--------------MKDGEPLLSQSLE- 3453
Query: 96 ALGVVSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLS 155
+ SL L + G G + C + AG A H L V+ P P + S
Sbjct: 3454 -------QGPSLQLEAVGAGDSGTYSCVAVSEAG----EARRHFQLTVMEP---PHIEDS 3499
Query: 156 NP----SPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTH 211
S GA + C +GT W G+AL + +
Sbjct: 3500 GQPTELSLTPGAPMELLCDA-QGTPQPNITWHKD-----GQALTRLENNSRATRVLRVRD 3553
Query: 212 LGWYMCSASNSVNRLSSDGAFLD--------------VIYLATRTCYKKKSVS------- 250
G Y C A + + V+ LA + SV
Sbjct: 3554 AGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKI 3613
Query: 251 -----GIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDK-----PVIT 300
GI L + A + F ERGR L + A G+ A G + T
Sbjct: 3614 TWHRDGIVLQEDAHTQ-FPERGRFLQ-LQALSTADSGDYSCTARNAAGSTSVAFRVEIHT 3671
Query: 301 MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHT-GPTYVIARAGRVH-- 357
+ + S + L C A P W +D + P + I G +
Sbjct: 3672 VPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQ 3731
Query: 358 ------TGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGL 411
G Y CLA NS R L + PP A+ PSP +TL P L
Sbjct: 3732 PVLAQDAGHYLCLASNSAGSDRQGR--DLRVLEPP------AIAPSPSNLTLTAHTPALL 3783
Query: 412 P--------PAQLQWEG--------PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPA 455
P P + W+ QG PSN A S F C +
Sbjct: 3784 PCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQ-FECVVSNEV 3842
Query: 456 LAPPALCTVMLWEPLGRPTCWS-----TATMGDQFIMLSCEWPGGEPPATLGWLDEQQQP 510
L V + P PT T TM ++L+C G P T+ W Q
Sbjct: 3843 GEAHRLYQVTVHVP---PTIADDQTDFTVTMMAP-VVLTCH-STGIPAPTVSWSKAGAQ- 3896
Query: 511 LGGSSS------SMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR 564
LG S S A+ + QA AGR +TC + H L ++A V +P
Sbjct: 3897 LGARGSGYRVSPSGALEIGQALPIHAGR-YTCSARNSAGVAHKHVFLTVQASP--VVKPL 3953
Query: 565 VSVLEG---GEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDA 621
SV+ E L C G P + W Q++ ++ T G QLR+
Sbjct: 3954 PSVVRAVAEEEVLLPCEA-SGIPRPTITW---QKEGLNVATGVSTQVLPGGQLRIAHASP 4009
Query: 622 DPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPN 657
+ A G Y C+A+N+ G++ L V P N
Sbjct: 4010 EDA---GNYLCIAKNSAGSAMGKTRLVVQVPPVIEN 4042
Score = 46.6 bits (109), Expect = 1e-04
Identities = 131/593 (22%), Positives = 203/593 (34%), Gaps = 110/593 (18%)
Query: 98 GVVSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVS-KPQVRLSN 156
GV L SL L + G + CQ + G A L V VP S + R +N
Sbjct: 1254 GVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRA----KLVVYVPPSIREDGRKAN 1309
Query: 157 PSPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYM 216
S + G S+ C P W A LVGV P+ GW +
Sbjct: 1310 VSGMAGQSLTLECDANGFPVP-EIVWLKDAQ------LVGV--------PLGWAGYGWDL 1354
Query: 217 CSASNSVNRLSSDGAFLDVIYLATRTCYKKKSVSGIRLLDG-AGLRRFKERGRMASYLSV 275
+RL +G +S+ R+ +G +GL + + +
Sbjct: 1355 GWGQVGGHRLLDEG----------------QSLHFPRIQEGDSGLYSCRAENQAGTAQRD 1398
Query: 276 FTVAVCGNCELRTVEADGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVW 335
F + V + A E LGL +V L C + P W
Sbjct: 1399 FHLLVLTPPSVLGAGA--------AQEVLGLAGA--------DVELQCWTSGVPTPQVEW 1442
Query: 336 LRDHTQVHTG-PTYVIARAGRV---------HTGLYTCLARNSYLDTRTQTTVQLTIYYP 385
+D V G P + G+V G Y C+A + + QL ++ P
Sbjct: 1443 TKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPA--GQQARDFQLRVHAP 1500
Query: 386 P----EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQL 441
P + V LLC G+P + W PT+ + V ++ QL
Sbjct: 1501 PTIWGSNETGEVAVMEDHLVQLLCE-ARGVPTPNITWFKDGALLPTS-TKVVYTRGGRQL 1558
Query: 442 PSG-------SVFTCTGQHPALAPPALCTVMLWEPL------GRPTCWSTATMGDQFIML 488
G V+TC + A + ++ P GRP + + + + L
Sbjct: 1559 QLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRP--YVVKAVAGRPVAL 1616
Query: 489 SCEWPGGEPPATLGWLDEQQQPLGGSSSSM-----AVHLLQAQEDLAGREFTCRGTHLLR 543
C G P TL W E P+ S+ S +V L++ + + ++C +
Sbjct: 1617 ECV-ARGHPSPTLSWHHEGL-PVAESNESRLETDGSVLRLESPGEASSGLYSC----VAS 1670
Query: 544 TPDPHCHLQLEA-----PQLDVAEP--RVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQ 596
+P LQ PQL VAE +V+ + G L C G+P + WL Q
Sbjct: 1671 SPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQA-SGSPVPTIQWL--QNG 1727
Query: 597 KVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEV 649
+ +G + +G L + + D H G + C A N G + V + V
Sbjct: 1728 RPAEELAGVQVASQGTTLHIDHVELD---HSGLFACQATNEAGTAGAEVEVSV 1777
Score = 46.2 bits (108), Expect = 1e-04
Identities = 91/388 (23%), Positives = 132/388 (34%), Gaps = 66/388 (17%)
Query: 319 VTLSCLAASNPPSHYVWLRDHTQVHT---------GPTYVIARAGRVHTGLYTCLARNSY 369
V L C+A +P W + V G + G +GLY+C+A +
Sbjct: 1614 VALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPA 1673
Query: 370 LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWP-------GGLPPAQLQWEGPQ 422
+ Q +V++ + P V VT + P G P +QW
Sbjct: 1674 GEAVLQYSVEVQV------PPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 1727
Query: 423 GP-----GPTAPSNVTWSHAA-AQLPSGSVFTCTGQHPALAPPALCTVML---WEPLGRP 473
P G S T H +L +F C + A A V + W P
Sbjct: 1728 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLE 1787
Query: 474 TCWSTATMGDQF---IMLSCEWP-------GGEPPATLGWLDEQQ---QPLGGSSSSMAV 520
G + +C+ P +PP GW +P G +
Sbjct: 1788 VPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLP 1847
Query: 521 HLLQAQE-DLAGRE-FTCRGTHLLRTPDPHCHLQ-LEAPQLDVAEPRVSVLEGGEAWLEC 577
LQ ++ DL +TC T+L L+ L P ++ +VLE LEC
Sbjct: 1848 PPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLEC 1907
Query: 578 SLRGGTPPAQLLWLGPQQ-----QKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQC 632
G PP + W Q V G +L E AQL DA G+Y+C
Sbjct: 1908 LAS-GVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLS----DA------GSYRC 1956
Query: 633 VARNAVGNSSQSVLLEVLRYPAPPNVTI 660
VA N G++ L LR PP +T+
Sbjct: 1957 VASNVAGSTE---LRYGLRVNVPPRITL 1981
Score = 44.7 bits (104), Expect = 4e-04
Identities = 87/371 (23%), Positives = 136/371 (36%), Gaps = 52/371 (14%)
Query: 314 SEREEVTLSCLAASNPPSHYVWLRDHTQVHTGP-TYVIARAGRV--------HTGLYTCL 364
+E L C A +P + W +D V + I +G + G YTC
Sbjct: 4050 TEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCT 4109
Query: 365 ARNSYLDTRTQTTVQLTIYYPP-----EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWE 419
A N+ R + V LTI P G S + + + L CA G P ++ W
Sbjct: 4110 AENAV--GRARRRVHLTILVLPVFTTLPGDRSLRLG---DRLWLRCAARGS-PTPRIGWT 4163
Query: 420 GPQGPGPTAPSNV----TWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP---LGR 472
P S T AA + C ++ A+ V + E G
Sbjct: 4164 VNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 4223
Query: 473 PTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGS-------SSSMAVHLLQA 525
+ +G I L C G+P + W+ + PL GS + S+ +H +
Sbjct: 4224 AFSYLVEPVGGS-IQLDCV-VRGDPVPDIHWIKDGL-PLRGSHLRHQLQNGSLTIH--RT 4278
Query: 526 QEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-VSVLEGGEAWLECSLRGGTP 584
+ D AGR + C + + L L++ + EP+ ++V G + L C G
Sbjct: 4279 ERDDAGR-YQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPT 4337
Query: 585 PAQLLWLGPQQQKVDPGTSGFMLH--PEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSS 642
P + WL Q P + L P+G+ + D GTY CVA N +G+++
Sbjct: 4338 PT-IEWL----QAGQPLRASRRLRTLPDGSLWLENVETGDA----GTYDCVAHNLLGSAT 4388
Query: 643 QSVLLEVLRYP 653
L V P
Sbjct: 4389 ARAFLVVRGEP 4399
Score = 43.5 bits (101), Expect = 8e-04
Identities = 137/597 (22%), Positives = 206/597 (34%), Gaps = 127/597 (21%)
Query: 100 VSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSP 159
VS L LG+ G + C+ +V G + L L V VP PQ+ P
Sbjct: 2213 VSAVGRLLYLGQAQLAQEGTYTCECSNVVGN----SSQDLQLEVHVP---PQIAGPREPP 2265
Query: 160 VEGASVVATCAVRE----GTEPVTFAWQHRA-PRG--LGEALVGVTEPLFQLDPVNRTHL 212
+ + V A E G P T W+ P G LG L + L ++ H
Sbjct: 2266 TQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSL-HVERAQAAHT 2324
Query: 213 GWYMCSASNSVNRLSSDGAFLDVIYLATRTCYKKKSVSGIRLLDGAGLRRFKERGRMASY 272
G Y C A N L G R+F+
Sbjct: 2325 GRYSCVAEN---------------------------------LAGRAERKFE-------- 2343
Query: 273 LSVFTVAVCGNCELRTVEADGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSH 332
LSV P + + ++PL A+ +TL C A PP
Sbjct: 2344 LSVLV----------------PPELIGDLDPL----TNITAALHSPLTLLCEAMGIPPPA 2383
Query: 333 YVWLRDHTQVHTGP-TYVIA--------RAGRVHTGLYTCLARNSYLDTRTQTTVQLTIY 383
W R V G TY++A + +GLY+CLA N + R +V++ +
Sbjct: 2384 IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVP 2443
Query: 384 YPPEGQPSCAVHPSPEAVT--LLCAWPGGLPPAQLQW--EG-PQGPGPT---APSNVTWS 435
E + V + T L+C G P +L W +G P G +P V
Sbjct: 2444 PSIENEDLEEVIKVLDGQTAHLMCNVTGH-PQPKLTWFKDGRPLARGDAHHISPDGVLLQ 2502
Query: 436 HAAAQLPSGSVFTCTG--------QHPALAPPALCTVMLWEPLGRPTCWSTATMGDQFIM 487
A L S ++C +H L+ L +L T T+ + I
Sbjct: 2503 VLQANLSSAGHYSCIAANAVGEKTKHFQLSV-LLAPTILGGAEDSADEEVTVTVNNP-IS 2560
Query: 488 LSCEWPGGEPPATLGWLD-----EQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLL 542
L CE P + W+ E + + + + +L AQ++ AG ++TC T+ L
Sbjct: 2561 LICE-ALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAG-QYTCVVTNEL 2618
Query: 543 RTPDPHCHLQL--------EAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQ 594
+ H+++ + P +V V LEC PP + W
Sbjct: 2619 GEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECE-SWAVPPPTIRWY-KD 2676
Query: 595 QQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQ--SVLLEV 649
Q V P +S + EG L++ G Y CVA N G Q +VL++V
Sbjct: 2677 GQPVTP-SSRLQVLGEGRLLQI---QPTQVSDSGRYLCVATNVAGEDDQDFNVLIQV 2729
Score = 38.9 bits (89), Expect = 0.021
Identities = 89/415 (21%), Positives = 147/415 (35%), Gaps = 56/415 (13%)
Query: 297 PVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV 356
PVI + L EE + V+L C A NP WL++ P + G+V
Sbjct: 2842 PVILGDTEELVEE-VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQV 2900
Query: 357 ---------HTGLYTCLARNSYLDTRTQTTVQLTIYYPPE------GQPSCAVHPSPEAV 401
Y C+A N T+++ + PP Q + ++ S V
Sbjct: 2901 LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQV--PPRIAGLDLEQVTAILNSS---V 2955
Query: 402 TLLCAWPGGLPPAQLQWEGPQGPGP-----TAPSNVTWSHAAAQLPSGSVFTCTGQHPA- 455
+L C P ++ Q P T A+L ++TC + A
Sbjct: 2956 SLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAG 3015
Query: 456 ----------LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLD 505
L PPA P G P +GD+ + LSCE P + D
Sbjct: 3016 RDQKLVQLSVLVPPAFRQA----PRG-PQDAVLVRVGDKAV-LSCETDALPEPTVTWYKD 3069
Query: 506 EQQQPLGGSSSSMA----VHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQL--D 559
Q L + ++ + + +AQ G ++C+ +++ L ++ P +
Sbjct: 3070 GQPLVLAQRTQALRGGQRLEIQEAQVSDKGL-YSCKVSNVAGEAVRTFTLTVQVPPTFEN 3128
Query: 560 VAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIY 619
VS + G L C + G P + WL + G + G +L+L
Sbjct: 3129 PKTETVSQVAGSPLVLTCDV-SGVPAPTVTWLKDRMPVESSAVHGVV--SRGGRLQLSRL 3185
Query: 620 DADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQL 674
A GTY CVA N + + ++ VL P + ++R + +EV+L
Sbjct: 3186 QPAQA---GTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRL 3237
Score = 33.9 bits (76), Expect = 0.66
Identities = 86/385 (22%), Positives = 131/385 (34%), Gaps = 47/385 (12%)
Query: 315 EREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV---------HTGLYTCLA 365
E L C + PP W R+ + G + + GRV + G Y+C A
Sbjct: 2764 ENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKA 2823
Query: 366 RNSYLDTRTQTTVQLTIYYPP-------EGQPSCAVHPSPEAVTLLCAWPGGLPP--AQL 416
N + +L + PP E V+ S V+L C G P + L
Sbjct: 2824 SNEVGEDWLH--YELLVLTPPVILGDTEELVEEVTVNAS-STVSLQCPALGNPVPTISWL 2880
Query: 417 QWEGPQGPGP---TAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP---L 470
Q P P P + A++ + + C ++ A + L T+ + P
Sbjct: 2881 QNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIA 2940
Query: 471 GRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSM-AVHLLQ---AQ 526
G TA + + L C+ P + D Q LG + H LQ A+
Sbjct: 2941 GLDLEQVTAILNSS-VSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRAR 2999
Query: 527 EDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-----VSVLEGGEAWLECSLRG 581
+G +TC + L + P PR V V G +A L C
Sbjct: 3000 LSDSGM-YTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCE-TD 3057
Query: 582 GTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNS 641
P + W Q V + + G Q RL I +A +G Y C N G +
Sbjct: 3058 ALPEPTVTWYKDGQPLVLAQRTQAL---RGGQ-RLEIQEAQ-VSDKGLYSCKVSNVAGEA 3112
Query: 642 SQSVLLEVLRYPA---PPNVTISRL 663
++ L V P P T+S++
Sbjct: 3113 VRTFTLTVQVPPTFENPKTETVSQV 3137
Score = 31.2 bits (69), Expect = 4.3
Identities = 51/201 (25%), Positives = 66/201 (32%), Gaps = 28/201 (13%)
Query: 34 PEAPVEEVVSVQGVRGGSVELACGSGPAPLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAI 93
P + + E ++V V SV L C S P VL + L PRP
Sbjct: 2070 PPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRP-------------- 2115
Query: 94 ASALGV-VSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQV 152
GV +S + L + GH+ C+ L+ AG + H L V V P
Sbjct: 2116 ----GVHLSADKALLQVDRADVWDAGHYTCEALNQAG----HSEKHYNLNVWVAPVFPLR 2167
Query: 153 RLSNPSPVEGASVVATCAVREGTEPVTFAW----QHRAPRGLGEALVGVTEPLFQLDPVN 208
+ EG +C R G +W Q G G V L L
Sbjct: 2168 ESHTLTVREGHPTSLSCECR-GVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQ 2226
Query: 209 RTHLGWYMCSASNSVNRLSSD 229
G Y C SN V S D
Sbjct: 2227 LAQEGTYTCECSNVVGNSSQD 2247
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 68.6 bits (166), Expect = 2e-11
Identities = 97/372 (26%), Positives = 144/372 (38%), Gaps = 53/372 (14%)
Query: 319 VTLSCLAASNPPSHYVWLRDHTQVHTG--PTYVIARAGRVHT---------GLYTCLARN 367
V L+C A P +WL+D V P + GRV T G Y+C+A +
Sbjct: 713 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 772
Query: 368 SYLDTRTQTTVQLTIYYPPE--GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPG 425
+ + R +Q ++ PP G+ + E+V L C PP W+ +
Sbjct: 773 AVGEDRQDVVLQ--VHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLE 830
Query: 426 PTAPSNVTWSHAAAQLPSGSV-----FTCTGQHPALAPPALCTVMLWEPLGRPTCWS-TA 479
P +++ A Q+ V +TC + A + +W P S T
Sbjct: 831 PRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTL 890
Query: 480 TMGDQF-IMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMA--------VHLLQAQEDLA 530
T+ + LSCE G P + W + Q PL G + + ++L QAQ
Sbjct: 891 TVREGHPTRLSCECRG-VPFPKISWRKDGQ-PLPGEGAGLQHVSAVGRLLYLGQAQLAQE 948
Query: 531 GREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-----VSVLEGGEAWLECSLRGGTPP 585
G +TC ++++ L++ P +A PR VSV++ G A LEC+ G PP
Sbjct: 949 GT-YTCECSNVVGNSSQDLQLEVHVPP-QIAGPREPPTQVSVVQDGVATLECNATGKPPP 1006
Query: 586 AQLLWLGPQQQKVDPG----TSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNS 641
Q + G G LH E AQ A H G Y CVA N G +
Sbjct: 1007 TVTWERDGQPVGAELGLQLQNQGQSLHVERAQ----------AAHTGRYSCVAENLAGRA 1056
Query: 642 SQSVLLEVLRYP 653
+ L VL P
Sbjct: 1057 ERKFELSVLVPP 1068
Score = 67.4 bits (163), Expect = 5e-11
Identities = 90/398 (22%), Positives = 149/398 (37%), Gaps = 69/398 (17%)
Query: 295 DKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVH----------- 343
+ P I P LT + L C A+ +P VW +D ++
Sbjct: 2480 EPPAIAPSPSNLT-----LTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLL 2534
Query: 344 TGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTL 403
++ G + + C+ N + Q+T++ PP + A + VT+
Sbjct: 2535 PSNALLLTAPGPQDSAQFECVVSNEVGEAHR--LYQVTVHVPP----TIADDQTDFTVTM 2588
Query: 404 LCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQL----------PSGSV------- 446
+ P L P PT V+WS A AQL PSG++
Sbjct: 2589 MA-------PVVLTCHSTGIPAPT----VSWSKAGAQLGARGSGYRVSPSGALEIGQALP 2637
Query: 447 -----FTCTGQHPA-LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPAT 500
+TC+ ++ A +A + + P+ +P + ++ ++L CE G P T
Sbjct: 2638 IHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCE-ASGIPRPT 2696
Query: 501 LGWLDEQQQPLGGSSSSMA----VHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAP 556
+ W E G S+ + + + A + AG + C + + L ++ P
Sbjct: 2697 ITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGN-YLCIAKNSAGSAMGKTRLVVQVP 2755
Query: 557 Q-LDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLR 615
++ P +S EG A+L C RG +P + W Q V F + P G L
Sbjct: 2756 PVIENGLPDLSTTEGSHAFLPCKARG-SPEPNITW-DKDGQPVSGAEGKFTIQPSGELLV 2813
Query: 616 LGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYP 653
+ D GTY C A NAVG + + V L +L P
Sbjct: 2814 KNLEGQDA----GTYTCTAENAVGRARRRVHLTILVLP 2847
Score = 67.0 bits (162), Expect = 7e-11
Identities = 94/374 (25%), Positives = 136/374 (36%), Gaps = 44/374 (11%)
Query: 315 EREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV---------HTGLYTCLA 365
E VTL CLA+ PP W + H V + ++ GRV G Y C+A
Sbjct: 617 ENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVA 676
Query: 366 RNSYLDTRTQTTVQLTIYYPPE-----GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQW-- 418
N + T+ L + PP P + +P V L C G P L W
Sbjct: 677 SN--VAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTP--VRLTCN-ATGAPSPTLMWLK 731
Query: 419 -EGPQGPGPTA-----PSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP--- 469
P P T P + A+A+ ++C + + P
Sbjct: 732 DGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSI 791
Query: 470 LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQ-QPLGGSSSSMAVHLLQAQ-- 526
LG + + + ++ + L C+ PP W D + +P G S LLQ
Sbjct: 792 LGEEL--NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRA 849
Query: 527 EDLAGREFTCRGTHLLRTPDPHCHLQL-EAPQLDVAEPR-VSVLEGGEAWLECSLRGGTP 584
+ +TC + + H +L + AP + E ++V EG L C R G P
Sbjct: 850 DVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECR-GVP 908
Query: 585 PAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQS 644
++ W Q PG + H L + A A GTY C N VGNSSQ
Sbjct: 909 FPKISWRKDGQPL--PGEGAGLQHVSAVGRLLYLGQAQLA-QEGTYTCECSNVVGNSSQD 965
Query: 645 VLLEVLRYPAPPNV 658
+ LEV PP +
Sbjct: 966 LQLEV---HVPPQI 976
Score = 65.5 bits (158), Expect = 2e-10
Identities = 115/473 (24%), Positives = 176/473 (37%), Gaps = 111/473 (23%)
Query: 256 DGAGLRRFKERGRMASYLSVFTVAVCGN--CELRTV----------EADGPDKPVITMEP 303
+GAGL+ GR+ YL +A G CE V E P + EP
Sbjct: 924 EGAGLQHVSAVGRLL-YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREP 982
Query: 304 ---LGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQV---------HTGPTYVIA 351
+ + ++G TL C A PP W RD V + G + +
Sbjct: 983 PTQVSVVQDGV-------ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVE 1035
Query: 352 RAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPE--------GQPSCAVHPSPEAVTL 403
RA HTG Y+C+A N L R + +L++ PPE + A+H SP +TL
Sbjct: 1036 RAQAAHTGRYSCVAEN--LAGRAERKFELSVLVPPELIGDLDPLTNITAALH-SP--LTL 1090
Query: 404 LCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAA--------QLPSGSVFTCTGQHPA 455
LC G+PP ++W +G P +P T+ A Q +++C + A
Sbjct: 1091 LCE-AMGIPPPAIRWF--RGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 1147
Query: 456 -----------LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWL 504
L PP++ L E + + Q L C G P L W
Sbjct: 1148 GEARRNFSVEVLVPPSIENEDLEEVI--------KVLDGQTAHLMCNVTG-HPQPKLTWF 1198
Query: 505 DEQQQPLGG-----SSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQ-LEAPQL 558
+ + G S + + +LQA AG ++C + + H L L AP +
Sbjct: 1199 KDGRPLARGDAHHISPDGVLLQVLQANLSSAGH-YSCIAANAVGEKTKHFQLSVLLAPTI 1257
Query: 559 -----DVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWL-------GPQQQKVDPGTSGFM 606
D A+ V+V L C P + W+ + ++ PGT G
Sbjct: 1258 LGGAEDSADEEVTVTVNNPISLICEALA-FPSPNITWMKDGAPFEASRNIQLLPGTHGLQ 1316
Query: 607 LHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVT 659
+ L DA G Y CV N +G + ++ +EVL PP+++
Sbjct: 1317 I------LNAQKEDA------GQYTCVVTNELGEAVKNYHVEVL---IPPSIS 1354
Score = 61.2 bits (147), Expect = 4e-09
Identities = 139/605 (22%), Positives = 211/605 (34%), Gaps = 105/605 (17%)
Query: 127 VAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTFAWQHRA 186
VA Q +A TL V VP + L + + +SV C V P ++
Sbjct: 1635 VAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ 1694
Query: 187 PRGLGEA--LVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYLATRTCY 244
LGE L+ T L QL + G Y C A N+ R ++ A R
Sbjct: 1695 ALSLGEEVFLLPGTHTL-QLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAP 1753
Query: 245 K-KKSVSGIRLLDGAGLRRFKE----------RGRMASYLSVFTVAVCGNCELRTVEADG 293
+ + +R+ D A L + + L+ T A+ G L EA
Sbjct: 1754 RGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQV 1813
Query: 294 PDKPVITMEPLGLTEEG-------------FWASEREEVT--------LSCLAASNPPSH 332
DK + + + + E F + E V+ L+C + P
Sbjct: 1814 SDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPT 1873
Query: 333 YVWLRDHTQVHTGPTY-VIARAGRVH--------TGLYTCLARNSYLDTRTQTTVQLTIY 383
WL+D V + + V++R GR+ G YTC+A N+ + R V + +
Sbjct: 1874 VTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVA 1933
Query: 384 YPPEGQPSCAVHPSPEA--VTLLCAWPGGLPPAQLQWEGPQGP-----GPTAPSNVTWSH 436
H E V L C G PP + W P GP H
Sbjct: 1934 PRIRSSGVAREHHVLEGQEVRLDCE-ADGQPPPDVAWLKDGSPLGQDMGP---------H 1983
Query: 437 AAAQLPSGSV------------FTCTGQHPALAPPALCTVMLWEP----LGRPTCWSTAT 480
L GS+ +TC +PA L TV + P G + +
Sbjct: 1984 LRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVS 2043
Query: 481 MGDQFIMLSCEWPGGEPPATLGWLDE-------QQQPLGGSSSSMAVHLLQAQEDLAGRE 533
+ + + C G PP + WL + Q+ L GS ++ + +Q + AG
Sbjct: 2044 RPGELVTMVCP-VRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLAD--AG-I 2099
Query: 534 FTCRGTHLLRTPDPHCHLQLEAPQLDVAEP-----RVSVLEGGEAWLECSLRGGTPPAQL 588
FTC D + LQ++ P V EP V V+ G L C R G P +
Sbjct: 2100 FTCVAASPAGVADRNFTLQVQVP--PVLEPVEFQNDVVVVRGSLVELPCEAR-GVPLPLV 2156
Query: 589 LWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLE 648
W+ + + +G L+L +A A GTY CVA + G + + L
Sbjct: 2157 SWMKDGEPLLSQSLE------QGPSLQL---EAVGAGDSGTYSCVAVSEAGEARRHFQLT 2207
Query: 649 VLRYP 653
V+ P
Sbjct: 2208 VMEPP 2212
Score = 60.5 bits (145), Expect = 7e-09
Identities = 87/367 (23%), Positives = 139/367 (37%), Gaps = 32/367 (8%)
Query: 319 VTLSCLAASNPPSHYVWLRD-----HTQVHTGPTYVIARAGRVHTGLYTCLARNSYLDTR 373
V L C A P W++D + GP+ + G +G Y+C+A + + R
Sbjct: 2142 VELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEAR 2201
Query: 374 TQTTVQLTIYYPPE----GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAP 429
QLT+ PP GQP+ + LLC G P + W G T
Sbjct: 2202 RH--FQLTVMEPPHIEDSGQPTELSLTPGAPMELLCD-AQGTPQPNITWH-KDGQALTRL 2257
Query: 430 SNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP---LGRPTCWSTATMGDQFI 486
N + + ++ ++TC + PA A V + P +G + +
Sbjct: 2258 ENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL 2317
Query: 487 MLSCEWPGGEPPATLGWLDE----QQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLL 542
+L C EP + W + Q+ LQA +++C +
Sbjct: 2318 VLECSVEA-EPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAA 2376
Query: 543 RTPDPHCHLQLEA-PQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPG 601
+ +++ P + P V+V A L C G PA L+ + +DP
Sbjct: 2377 GSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADG--VPAPLVSWRKDRVPLDPR 2434
Query: 602 TSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPA----PPN 657
+ F + PEG+ LR+ A A H Y C+A N+ G+ Q L VL PA P N
Sbjct: 2435 SPRFEILPEGS-LRIQPVLAQDAGH---YLCLASNSAGSDRQGRDLRVLEPPAIAPSPSN 2490
Query: 658 VTISRLT 664
+T++ T
Sbjct: 2491 LTLTAHT 2497
Score = 60.1 bits (144), Expect = 9e-09
Identities = 141/622 (22%), Positives = 224/622 (36%), Gaps = 91/622 (14%)
Query: 107 LVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVV 166
L + E +G + C+V +VAG A TL V VP + + S V G+ +V
Sbjct: 1806 LEIQEAQVSDKGLYSCKVSNVAG----EAVRTFTLTVQVPPTFENPKTETVSQVAGSPLV 1861
Query: 167 ATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEP--LFQLDPVNRTHLGWYMCSASNS-- 222
TC V G T W A+ GV QL + G Y C A N+
Sbjct: 1862 LTCDV-SGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQA 1920
Query: 223 ------------VNRLSSDGAFLDVIYLATRTCYKKKSVSGIRLLDGAGLRRFKERGR-- 268
R+ S G + L + G D A L+ G+
Sbjct: 1921 EARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM 1980
Query: 269 ---MASYLSVFTVAVCGNCELRTVEAD----------GPDKPVITMEPL-------GLTE 308
+ YL ++ + G LR +A G D + T+ L G
Sbjct: 1981 GPHLRFYLDGGSLVLKG---LRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADG 2037
Query: 309 EGFWASEREE-VTLSCLAASNPPSHYVWLRD--------HTQVH-TGPTYVIARAGRVHT 358
G S E VT+ C +PP H WL+D T +H +G T I++
Sbjct: 2038 SGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADA 2097
Query: 359 GLYTCLARNSYLDTRTQTTVQLTIYYPPEGQP----SCAVHPSPEAVTLLCAWPGGLPPA 414
G++TC+A + T+Q+ + PP +P + V V L C G+P
Sbjct: 2098 GIFTCVAASPAGVADRNFTLQVQV--PPVLEPVEFQNDVVVVRGSLVELPCE-ARGVPLP 2154
Query: 415 QLQW--EGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP--- 469
+ W +G + + A ++C A + + EP
Sbjct: 2155 LVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHI 2214
Query: 470 --LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQE 527
G+PT S ++ + G P + W + Q ++S A +L+ ++
Sbjct: 2215 EDSGQPTELSLTPGAPMELLCDAQ---GTPQPNITWHKDGQALTRLENNSRATRVLRVRD 2271
Query: 528 DLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR----VSVLEGGEAWLECSLRGGT 583
AG +TC + ++++AP ++ PR V L G+ LECS+
Sbjct: 2272 --AGL-YTCLAESPAGAIEKSFRVRVQAPP-NIVGPRGPRFVVGLAPGQLVLECSVEA-E 2326
Query: 584 PPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQ 643
P ++ W + + F QL+ + AD G Y C ARNA G++S
Sbjct: 2327 PAPKITWHRDGIVLQEDAHTQFPERGRFLQLQ-ALSTADS----GDYSCTARNAAGSTSV 2381
Query: 644 SVLLEVLRYP----APPNVTIS 661
+ +E+ P PP V +S
Sbjct: 2382 AFRVEIHTVPTIRSGPPAVNVS 2403
Score = 56.6 bits (135), Expect = 1e-07
Identities = 94/400 (23%), Positives = 139/400 (34%), Gaps = 77/400 (19%)
Query: 317 EEVTLSCLAASNPPSHYVWLRD------------------------HTQVHTGPTYVIAR 352
+ +TL C A P VWL+D H + G + R
Sbjct: 34 QSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPR 93
Query: 353 AGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPE----GQPSCAVHPSPEAVTLLCAWP 408
+GLY+C A N Q L + PP G + + V L C W
Sbjct: 94 IQEGDSGLYSCRAENQ--AGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQC-WT 150
Query: 409 GGLPPAQLQWEGPQGPG-PTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLW 467
G+P Q++W + P P P H Q G V TG H C + +
Sbjct: 151 SGVPTPQVEWTKDRQPVLPGGP------HLQVQ-EDGQVLRITGSHVGDEGRYQC--VAF 201
Query: 468 EPLGR------------PTCWST------ATMGDQFIMLSCEWPGGEPPATLGWLDEQQQ 509
P G+ PT W + A M D + L CE G P + D
Sbjct: 202 SPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL 261
Query: 510 PLGG----SSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEA-PQLDVAEPR 564
P + + L +AQ AG +TC+ ++ + + L + P ++ A R
Sbjct: 262 PTSTKVVYTRGGRQLQLGRAQSSDAG-VYTCKASNAVGAAEKATRLDVYVPPTIEGAGGR 320
Query: 565 ---VSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDA 621
V + G LEC RG P L W + S L +G+ LRL ++
Sbjct: 321 PYVVKAVAGRPVALECVARGHPSPT-LSWHHEGLPVAESNES--RLETDGSVLRL---ES 374
Query: 622 DPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTIS 661
G Y CVA + G ++VL + PP + ++
Sbjct: 375 PGEASSGLYSCVASSPAG---EAVLQYSVEVQVPPQLLVA 411
Score = 55.1 bits (131), Expect = 3e-07
Identities = 90/391 (23%), Positives = 142/391 (36%), Gaps = 55/391 (14%)
Query: 305 GLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGP---------TYVIARAGR 355
GL E A V+L C ++P W +D + G T + RA
Sbjct: 1659 GLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARL 1718
Query: 356 VHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQ-----PSCAVHPSPEAVTLLCAWPGG 410
+G+YTC A N+ R Q VQL++ PP + P AV +L
Sbjct: 1719 SDSGMYTCEALNA--AGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDA 1776
Query: 411 LPPAQLQWEGPQGPGPTAPSNVTWSHA------AAQLPSGSVFTCTGQHPALAPPALCTV 464
LP + W P A AQ+ +++C + A T+
Sbjct: 1777 LPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTL 1836
Query: 465 MLWEP--LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHL 522
+ P P + + + ++L+C+ G P T+ WL ++ S AVH
Sbjct: 1837 TVQVPPTFENPKTETVSQVAGSPLVLTCD-VSGVPAPTVTWLKDRM-----PVESSAVHG 1890
Query: 523 LQAQE---DLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRV---------SVLEG 570
+ ++ L+ + GT+ + + + + PR+ VLEG
Sbjct: 1891 VVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEG 1950
Query: 571 GEAWLECSLRGGTPPAQLLWL---GPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHR 627
E L+C G PP + WL P Q + P ++ +G L L A A
Sbjct: 1951 QEVRLDCE-ADGQPPPDVAWLKDGSPLGQDMGPHLRFYL---DGGSLVLKGLRASDA--- 2003
Query: 628 GTYQCVARNAVGNSSQSVLLEVLRYPAPPNV 658
G Y CVA N G ++ + VL PP +
Sbjct: 2004 GAYTCVAHNPAGEDARLHTVNVL---VPPTI 2031
Score = 54.7 bits (130), Expect = 4e-07
Identities = 96/392 (24%), Positives = 137/392 (34%), Gaps = 75/392 (19%)
Query: 319 VTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGR---------VHTGLYTCLARNSY 369
V L C A P + W +D + T V R GR G+YTC A N+
Sbjct: 238 VQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAV 297
Query: 370 LDTRTQTTVQLTIYYPPE-----GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQW--EGPQ 422
+ +L +Y PP G+P + V L C G P L W EG
Sbjct: 298 --GAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECV-ARGHPSPTLSWHHEGL- 353
Query: 423 GPGPTAPSNVTWSHAAAQL--------PSGSVFTCTGQHPA-----------LAPPALCT 463
P A SN + + S +++C PA PP L
Sbjct: 354 ---PVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQL-- 408
Query: 464 VMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQ--QPLGG---SSSSM 518
++ E LG+ T T+ Q + L C+ G P T+ WL + + L G +S
Sbjct: 409 -LVAEGLGQVT-----TIVGQPLELPCQ-ASGSPVPTIQWLQNGRPAEELAGVQVASQGT 461
Query: 519 AVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLE---APQLDVAEPRVSVLEGGEAWL 575
+H+ + D +G F C+ T+ T + + AP V E + G
Sbjct: 462 TLHIDHVELDHSGL-FACQATNEAGTAGAEVEVSVHGEWAP--GVLEVPIGQYHWGXEHH 518
Query: 576 ECSLRGGTPPAQLLW-LGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADP--------AHH 626
PP W P+ V+ S L E + + Y P
Sbjct: 519 SSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVA-YSLPPPLQIEKVDLRD 577
Query: 627 RGTYQCVARNAVGNSSQSVLLEVLRYPAPPNV 658
G Y C A N G S + V L+VL PPN+
Sbjct: 578 EGIYTCAATNLAGESKREVALKVL---VPPNI 606
Score = 52.4 bits (124), Expect = 2e-06
Identities = 134/617 (21%), Positives = 218/617 (35%), Gaps = 106/617 (17%)
Query: 118 GHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLS--NPSPVEGASVVATCAVREGT 175
G + C ++AG + + L VLVP P + N + +E ASV C + G
Sbjct: 579 GIYTCAATNLAG----ESKREVALKVLVP---PNIEPGPVNKAVLENASVTLEC-LASGV 630
Query: 176 EPVTFAW--QHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVN--------- 224
P +W H+ V V + +++ + G Y C ASN
Sbjct: 631 PPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLR 690
Query: 225 -----RLSSDGAFLDVIYLATR---TCYKKKSVSG--IRLLDG--------AGLRRFKER 266
R++ + + + T TC + S + L DG GL+ F
Sbjct: 691 VNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPG- 749
Query: 267 GRMASYLSVFTVAVCGNCELRTVEADGPDKPVITME----PLGLTEE-GFWASEREEVTL 321
GR+ + S + G V A G D+ + ++ P L EE E V L
Sbjct: 750 GRVLTLASA-RASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVAL 808
Query: 322 SCLAASNPPSHYVWLRDHTQVHTGPTYVIA---------RAGRVHTGLYTCLARNS--YL 370
C + + PP W +D + P ++ RA G YTC A N +
Sbjct: 809 ECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHS 868
Query: 371 DTRTQTTVQLTIYYPPEGQPSCAVHPS-PEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAP 429
+ V + +P + V P ++ C G+P ++ W P P
Sbjct: 869 EKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECR---GVPFPKISWRKDGQPLPGEG 925
Query: 430 SNVTWSHAA--------AQLPSGSVFTCTG-----------QHPALAPPALCTVMLWEPL 470
+ + A AQL +TC Q PP + P
Sbjct: 926 AGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAG-----PR 980
Query: 471 GRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGS------SSSMAVHLLQ 524
PT + + D L C G+PP T+ W + QP+G + ++H+ +
Sbjct: 981 EPPT--QVSVVQDGVATLECN-ATGKPPPTVTW-ERDGQPVGAELGLQLQNQGQSLHVER 1036
Query: 525 AQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAE----PRVSVLEGGEAWLECSLR 580
AQ GR ++C +L + L + P + + ++ L C
Sbjct: 1037 AQAAHTGR-YSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAM 1095
Query: 581 GGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGN 640
G PPA + G ++ V PG ++L G L++ G Y C+A N G
Sbjct: 1096 GIPPPAIRWFRG--EEPVSPGEDTYLL-AGGWMLKM---TQTQEQDSGLYSCLASNEAGE 1149
Query: 641 SSQSVLLEVLRYPAPPN 657
+ ++ +EVL P+ N
Sbjct: 1150 ARRNFSVEVLVPPSIEN 1166
Score = 48.1 bits (113), Expect = 3e-05
Identities = 165/696 (23%), Positives = 228/696 (32%), Gaps = 137/696 (19%)
Query: 37 PVEEVVSVQGVRGGSVELACGSGPAPL-LVLWSFTPLGSLVPRPVAVTDGAMSKVEAIAS 95
PVE V VRG VEL C + PL LV W + DG +++
Sbjct: 2127 PVEFQNDVVVVRGSLVELPCEARGVPLPLVSW--------------MKDGEPLLSQSLE- 2171
Query: 96 ALGVVSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLS 155
+ SL L + G G + C + AG A H L V+ P P + S
Sbjct: 2172 -------QGPSLQLEAVGAGDSGTYSCVAVSEAG----EARRHFQLTVMEP---PHIEDS 2217
Query: 156 NP----SPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTH 211
S GA + C +GT W G+AL + +
Sbjct: 2218 GQPTELSLTPGAPMELLCDA-QGTPQPNITWHKD-----GQALTRLENNSRATRVLRVRD 2271
Query: 212 LGWYMCSASNSVNRLSSDGAFLD--------------VIYLATRTCYKKKSVS------- 250
G Y C A + + V+ LA + SV
Sbjct: 2272 AGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKI 2331
Query: 251 -----GIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDK-----PVIT 300
GI L + A + F ERGR L + A G+ A G + T
Sbjct: 2332 TWHRDGIVLQEDAHTQ-FPERGRFLQ-LQALSTADSGDYSCTARNAAGSTSVAFRVEIHT 2389
Query: 301 MEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHT-GPTYVIARAGRVH-- 357
+ + S + L C A P W +D + P + I G +
Sbjct: 2390 VPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQ 2449
Query: 358 ------TGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGL 411
G Y CLA NS R L + PP A+ PSP +TL P L
Sbjct: 2450 PVLAQDAGHYLCLASNSAGSDRQGR--DLRVLEPP------AIAPSPSNLTLTAHTPALL 2501
Query: 412 P--------PAQLQWEG--------PQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPA 455
P P + W+ QG PSN A S F C +
Sbjct: 2502 PCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQ-FECVVSNEV 2560
Query: 456 LAPPALCTVMLWEPLGRPTCWS-----TATMGDQFIMLSCEWPGGEPPATLGWLDEQQQP 510
L V + P PT T TM ++L+C G P T+ W Q
Sbjct: 2561 GEAHRLYQVTVHVP---PTIADDQTDFTVTMMAP-VVLTCH-STGIPAPTVSWSKAGAQ- 2614
Query: 511 LGGSSS------SMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR 564
LG S S A+ + QA AGR +TC + H L ++A V +P
Sbjct: 2615 LGARGSGYRVSPSGALEIGQALPIHAGR-YTCSARNSAGVAHKHVFLTVQASP--VVKPL 2671
Query: 565 VSVLEG---GEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDA 621
SV+ E L C G P + W Q++ ++ T G QLR+
Sbjct: 2672 PSVVRAVAEEEVLLPCEA-SGIPRPTITW---QKEGLNVATGVSTQVLPGGQLRIAHASP 2727
Query: 622 DPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPN 657
+ A G Y C+A+N+ G++ L V P N
Sbjct: 2728 EDA---GNYLCIAKNSAGSAMGKTRLVVQVPPVIEN 2760
Score = 46.2 bits (108), Expect = 1e-04
Identities = 91/388 (23%), Positives = 132/388 (34%), Gaps = 66/388 (17%)
Query: 319 VTLSCLAASNPPSHYVWLRDHTQVHT---------GPTYVIARAGRVHTGLYTCLARNSY 369
V L C+A +P W + V G + G +GLY+C+A +
Sbjct: 332 VALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPA 391
Query: 370 LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWP-------GGLPPAQLQWEGPQ 422
+ Q +V++ + P V VT + P G P +QW
Sbjct: 392 GEAVLQYSVEVQV------PPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNG 445
Query: 423 GP-----GPTAPSNVTWSHAA-AQLPSGSVFTCTGQHPALAPPALCTVML---WEPLGRP 473
P G S T H +L +F C + A A V + W P
Sbjct: 446 RPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLE 505
Query: 474 TCWSTATMGDQF---IMLSCEWP-------GGEPPATLGWLDEQQ---QPLGGSSSSMAV 520
G + +C+ P +PP GW +P G +
Sbjct: 506 VPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLP 565
Query: 521 HLLQAQE-DLAGRE-FTCRGTHLLRTPDPHCHLQ-LEAPQLDVAEPRVSVLEGGEAWLEC 577
LQ ++ DL +TC T+L L+ L P ++ +VLE LEC
Sbjct: 566 PPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLEC 625
Query: 578 SLRGGTPPAQLLWLGPQQ-----QKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQC 632
G PP + W Q V G +L E AQL DA G+Y+C
Sbjct: 626 LAS-GVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLS----DA------GSYRC 674
Query: 633 VARNAVGNSSQSVLLEVLRYPAPPNVTI 660
VA N G++ L LR PP +T+
Sbjct: 675 VASNVAGSTE---LRYGLRVNVPPRITL 699
Score = 45.1 bits (105), Expect = 3e-04
Identities = 84/371 (22%), Positives = 135/371 (36%), Gaps = 57/371 (15%)
Query: 318 EVTLSCLAASNPPSHYVWLRDHTQVHTG-PTYVIARAGRV---------HTGLYTCLARN 367
+V L C + P W +D V G P + G+V G Y C+A +
Sbjct: 143 DVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFS 202
Query: 368 SYLDTRTQTTVQLTIYYPP----EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQG 423
+ QL ++ PP + V LLC G+P + W
Sbjct: 203 PA--GQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCE-ARGVPTPNITWFKDGA 259
Query: 424 PGPTAPSNVTWSHAAAQLPSG-------SVFTCTGQHPALAPPALCTVMLWEPL------ 470
PT+ + V ++ QL G V+TC + A + ++ P
Sbjct: 260 LLPTS-TKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAG 318
Query: 471 GRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSM-----AVHLLQA 525
GRP + + + + L C G P TL W E P+ S+ S +V L++
Sbjct: 319 GRP--YVVKAVAGRPVALECV-ARGHPSPTLSWHHEGL-PVAESNESRLETDGSVLRLES 374
Query: 526 QEDLAGREFTCRGTHLLRTPDPHCHLQLEA-----PQLDVAEP--RVSVLEGGEAWLECS 578
+ + ++C + +P LQ PQL VAE +V+ + G L C
Sbjct: 375 PGEASSGLYSC----VASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQ 430
Query: 579 LRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAV 638
G+P + WL Q + +G + +G L + + D H G + C A N
Sbjct: 431 A-SGSPVPTIQWL--QNGRPAEELAGVQVASQGTTLHIDHVELD---HSGLFACQATNEA 484
Query: 639 GNSSQSVLLEV 649
G + V + V
Sbjct: 485 GTAGAEVEVSV 495
Score = 44.7 bits (104), Expect = 4e-04
Identities = 137/597 (22%), Positives = 206/597 (34%), Gaps = 127/597 (21%)
Query: 100 VSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSP 159
VS L LG+ G + C+ +V G + L L V VP PQ+ P
Sbjct: 931 VSAVGRLLYLGQAQLAQEGTYTCECSNVVGN----SSQDLQLEVHVP---PQIAGPREPP 983
Query: 160 VEGASVVATCAVRE----GTEPVTFAWQHRA-PRG--LGEALVGVTEPLFQLDPVNRTHL 212
+ + V A E G P T W+ P G LG L + L ++ H
Sbjct: 984 TQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSL-HVERAQAAHT 1042
Query: 213 GWYMCSASNSVNRLSSDGAFLDVIYLATRTCYKKKSVSGIRLLDGAGLRRFKERGRMASY 272
G Y C A N L G R+F+
Sbjct: 1043 GRYSCVAEN---------------------------------LAGRAERKFE-------- 1061
Query: 273 LSVFTVAVCGNCELRTVEADGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSH 332
LSV P + + ++PL A+ +TL C A PP
Sbjct: 1062 LSVLV----------------PPELIGDLDPL----TNITAALHSPLTLLCEAMGIPPPA 1101
Query: 333 YVWLRDHTQVHTGP-TYVIA--------RAGRVHTGLYTCLARNSYLDTRTQTTVQLTIY 383
W R V G TY++A + +GLY+CLA N + R +V++ +
Sbjct: 1102 IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVP 1161
Query: 384 YPPEGQPSCAVHPSPEAVT--LLCAWPGGLPPAQLQW--EG-PQGPGPT---APSNVTWS 435
E + V + T L+C G P +L W +G P G +P V
Sbjct: 1162 PSIENEDLEEVIKVLDGQTAHLMCNVTGH-PQPKLTWFKDGRPLARGDAHHISPDGVLLQ 1220
Query: 436 HAAAQLPSGSVFTCTG--------QHPALAPPALCTVMLWEPLGRPTCWSTATMGDQFIM 487
A L S ++C +H L+ L +L T T+ + I
Sbjct: 1221 VLQANLSSAGHYSCIAANAVGEKTKHFQLSV-LLAPTILGGAEDSADEEVTVTVNNP-IS 1278
Query: 488 LSCEWPGGEPPATLGWLD-----EQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLL 542
L CE P + W+ E + + + + +L AQ++ AG ++TC T+ L
Sbjct: 1279 LICE-ALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAG-QYTCVVTNEL 1336
Query: 543 RTPDPHCHLQL--------EAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQ 594
+ H+++ + P +V V LEC PP + W
Sbjct: 1337 GEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECE-SWAVPPPTIRWY-KD 1394
Query: 595 QQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQ--SVLLEV 649
Q V P +S + EG L++ G Y CVA N G Q +VL++V
Sbjct: 1395 GQPVTP-SSRLQVLGEGRLLQI---QPTQVSDSGRYLCVATNVAGEDDQDFNVLIQV 1447
Score = 42.4 bits (98), Expect = 0.002
Identities = 85/369 (23%), Positives = 135/369 (36%), Gaps = 48/369 (13%)
Query: 314 SEREEVTLSCLAASNPPSHYVWLRDHTQVHTGP-TYVIARAGRV--------HTGLYTCL 364
+E L C A +P + W +D V + I +G + G YTC
Sbjct: 2768 TEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCT 2827
Query: 365 ARNSYLDTRTQTTVQLTIYYPP-----EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWE 419
A N+ R + V LTI P G S + + + L CA G P ++ W
Sbjct: 2828 AENAV--GRARRRVHLTILVLPVFTTLPGDRSLRLG---DRLWLRCAARGS-PTPRIGWT 2881
Query: 420 GPQGPGPTAPSNV----TWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP---LGR 472
P S T AA + C ++ A+ V + E G
Sbjct: 2882 VNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 2941
Query: 473 PTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSS-----SSMAVHLLQAQE 527
+ +G I L C G+P + W+ + PL GS + ++ + + +
Sbjct: 2942 AFSYLVEPVGGS-IQLDCV-VRGDPVPDIHWIKDGL-PLRGSHLRHQLQNGSLTIRRTER 2998
Query: 528 DLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-VSVLEGGEAWLECSLRGGTPPA 586
D AGR + C + + L L++ + EP+ ++V G + L C G P
Sbjct: 2999 DDAGR-YQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPT 3057
Query: 587 QLLWLGPQQQKVDPGTSGFMLH--PEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQS 644
+ WL Q P + L P+G+ + D GTY CVA N +G+++
Sbjct: 3058 -IEWL----QAGQPLRASRRLRTLPDGSLWLENVETGDA----GTYDCVAHNLLGSATAR 3108
Query: 645 VLLEVLRYP 653
L V P
Sbjct: 3109 AFLVVRGEP 3117
Score = 38.9 bits (89), Expect = 0.021
Identities = 89/415 (21%), Positives = 147/415 (35%), Gaps = 56/415 (13%)
Query: 297 PVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV 356
PVI + L EE + V+L C A NP WL++ P + G+V
Sbjct: 1560 PVILGDTEELVEE-VTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQV 1618
Query: 357 ---------HTGLYTCLARNSYLDTRTQTTVQLTIYYPPE------GQPSCAVHPSPEAV 401
Y C+A N T+++ + PP Q + ++ S V
Sbjct: 1619 LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQV--PPRIAGLDLEQVTAILNSS---V 1673
Query: 402 TLLCAWPGGLPPAQLQWEGPQGPGP-----TAPSNVTWSHAAAQLPSGSVFTCTGQHPA- 455
+L C P ++ Q P T A+L ++TC + A
Sbjct: 1674 SLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAG 1733
Query: 456 ----------LAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLD 505
L PPA P G P +GD+ + LSCE P + D
Sbjct: 1734 RDQKLVQLSVLVPPAFRQA----PRG-PQDAVLVRVGDKAV-LSCETDALPEPTVTWYKD 1787
Query: 506 EQQQPLGGSSSSMA----VHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQL--D 559
Q L + ++ + + +AQ G ++C+ +++ L ++ P +
Sbjct: 1788 GQPLVLAQRTQALRGGQRLEIQEAQVSDKGL-YSCKVSNVAGEAVRTFTLTVQVPPTFEN 1846
Query: 560 VAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIY 619
VS + G L C + G P + WL + G + G +L+L
Sbjct: 1847 PKTETVSQVAGSPLVLTCDV-SGVPAPTVTWLKDRMPVESSAVHGVV--SRGGRLQLSRL 1903
Query: 620 DADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQL 674
A GTY CVA N + + ++ VL P + ++R + +EV+L
Sbjct: 1904 QPAQA---GTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRL 1955
Score = 33.9 bits (76), Expect = 0.66
Identities = 86/385 (22%), Positives = 131/385 (34%), Gaps = 47/385 (12%)
Query: 315 EREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV---------HTGLYTCLA 365
E L C + PP W R+ + G + + GRV + G Y+C A
Sbjct: 1482 ENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKA 1541
Query: 366 RNSYLDTRTQTTVQLTIYYPP-------EGQPSCAVHPSPEAVTLLCAWPGGLPP--AQL 416
N + +L + PP E V+ S V+L C G P + L
Sbjct: 1542 SNEVGEDWLH--YELLVLTPPVILGDTEELVEEVTVNAS-STVSLQCPALGNPVPTISWL 1598
Query: 417 QWEGPQGPGP---TAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP---L 470
Q P P P + A++ + + C ++ A + L T+ + P
Sbjct: 1599 QNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIA 1658
Query: 471 GRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSM-AVHLLQ---AQ 526
G TA + + L C+ P + D Q LG + H LQ A+
Sbjct: 1659 GLDLEQVTAILNSS-VSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRAR 1717
Query: 527 EDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPR-----VSVLEGGEAWLECSLRG 581
+G +TC + L + P PR V V G +A L C
Sbjct: 1718 LSDSGM-YTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCE-TD 1775
Query: 582 GTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNS 641
P + W Q V + + G Q RL I +A +G Y C N G +
Sbjct: 1776 ALPEPTVTWYKDGQPLVLAQRTQAL---RGGQ-RLEIQEAQ-VSDKGLYSCKVSNVAGEA 1830
Query: 642 SQSVLLEVLRYPA---PPNVTISRL 663
++ L V P P T+S++
Sbjct: 1831 VRTFTLTVQVPPTFENPKTETVSQV 1855
Score = 30.8 bits (68), Expect = 5.6
Identities = 51/201 (25%), Positives = 66/201 (32%), Gaps = 28/201 (13%)
Query: 34 PEAPVEEVVSVQGVRGGSVELACGSGPAPLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAI 93
P + + E ++V V SV L C S P VL + L PRP
Sbjct: 788 PPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRP-------------- 833
Query: 94 ASALGV-VSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQV 152
GV +S + L + GH+ C+ L+ AG + H L V V P
Sbjct: 834 ----GVHLSADKALLQVDRADVWDAGHYTCEALNQAG----HSEKHYNLNVWVAPVFPLR 885
Query: 153 RLSNPSPVEGASVVATCAVREGTEPVTFAW----QHRAPRGLGEALVGVTEPLFQLDPVN 208
+ EG +C R G +W Q G G V L L
Sbjct: 886 ESHTLTVREGHPTRLSCECR-GVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQ 944
Query: 209 RTHLGWYMCSASNSVNRLSSD 229
G Y C SN V S D
Sbjct: 945 LAQEGTYTCECSNVVGNSSQD 965
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 65.9 bits (159), Expect = 2e-10
Identities = 100/377 (26%), Positives = 144/377 (38%), Gaps = 50/377 (13%)
Query: 314 SEREEVTLSCLAASNPPSHYVW------LRDHTQVHTGP--TYVIARAGRVHTGLYTCLA 365
S+ EV +SC A+ P H W L++ +++H T +I G Y+C A
Sbjct: 503 SQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA 562
Query: 366 RNSYLDTRTQTTVQLTIYY--PPEGQPSCAVH--PSPEAVTLLCAWPGGLPPAQLQWEGP 421
N + T +T +T+YY PP AV E L+C G PP + + G
Sbjct: 563 TNE-VGTDQET---VTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGG 618
Query: 422 QGP--GPTAPSNVTWSHAAAQLPSGSVFTCT-----GQHPALAPPALCTVMLWEPLGRPT 474
P S+ AAQ +TC G A A+ L R
Sbjct: 619 LEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDV 678
Query: 475 CWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLG-------GSSSSMAVHLLQAQE 527
T +G + +L+C G PP T+ W QPLG GS S + E
Sbjct: 679 ---TVELG-RSALLACR-ATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFE 733
Query: 528 DLAGRE---FTCRGTHLLRTPDPHCHLQLEA---PQLDVAEPRVSVLEGGEAWLECSLRG 581
+A + + C ++ L + PQ+ + P V VLEG L C +
Sbjct: 734 SVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLA 793
Query: 582 GTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNS 641
G P + WL + + PG S + +G+ L L D H G Y CVA N G+
Sbjct: 794 GRPLPERHWL-KDGRPLPPG-SRHSIRADGS-LHL---DRALQEHAGRYSCVATNTAGSQ 847
Query: 642 SQSVLLEVLRYPAPPNV 658
+ V L V PP +
Sbjct: 848 HRDVELVV---QVPPRI 861
Score = 55.8 bits (133), Expect = 2e-07
Identities = 79/337 (23%), Positives = 122/337 (36%), Gaps = 26/337 (7%)
Query: 339 HTQVHTGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSP 398
H Q ++ I RA + G Y C A + R + + +T PP+ P+ V SP
Sbjct: 355 HFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVT-DPPPQLVPAPNVTVSP 413
Query: 399 EAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAP 458
+L G P L W P + V + SG + T G++ +A
Sbjct: 414 GETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVAS 473
Query: 459 PA--LCTVMLWEPLGRPTCWSTATMGDQF-----IMLSCEWPGGEPPATLGWLDEQQQPL 511
A + +W + S T F + +SC G P + W E Q
Sbjct: 474 NANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCS-ASGYPTPHISWSRESQALQ 532
Query: 512 GGSS---SSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHL-QLEAPQLDVAEPRVSV 567
S + ++Q ++C+ T+ + T L + P + V V
Sbjct: 533 EDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLV 592
Query: 568 LEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHR 627
G EA L C G PP +++W G +L PEG+ A
Sbjct: 593 AVGEEAVLVCE-ASGVPPPRVIWY--------RGGLEMILAPEGSSSGKLRIPAAQERDA 643
Query: 628 GTYQCVARNAVGNSSQSVLLEVLRYP----APPNVTI 660
GTY C A N +G++S + L V P P +VT+
Sbjct: 644 GTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTV 680
Score = 54.3 bits (129), Expect = 5e-07
Identities = 89/372 (23%), Positives = 130/372 (34%), Gaps = 52/372 (13%)
Query: 317 EEVTLSCLAASNPPSHYVWLRDHTQVHTGPT------YVIARAGRVHTGLYTCLARNSYL 370
EE L C A+ PP +W R ++ P I A G YTC A N
Sbjct: 596 EEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELG 655
Query: 371 DTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVT-------LLCAWPGGLPPAQLQWEGPQG 423
D + +QL + + P+ + P VT LL G PP + W G
Sbjct: 656 DASAE--IQLAVGHAPQ------LTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDG 707
Query: 424 PGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTV------------MLWEPLG 471
P + ++ P V P P +C ++
Sbjct: 708 Q-PLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHA 766
Query: 472 RPTCWSTA----TMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSM----AVHLL 523
P S+A + Q + L C G P WL + + GS S+ ++HL
Sbjct: 767 PPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLD 826
Query: 524 QAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAP-QLDVAEPRVSVLEGGEAWLECSLRGG 582
+A ++ AGR ++C T+ + L ++ P ++ EG A L C + G
Sbjct: 827 RALQEHAGR-YSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPC-VASG 884
Query: 583 TPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADP-AHHRGTYQCVARNAVGNS 641
P + W G + + EG L A P A G Y C A N VG S
Sbjct: 885 VPAPTITWTKETNALTSRGPH-YNVSKEGTLLI-----AQPSAQDAGAYVCTATNTVGFS 938
Query: 642 SQSVLLEVLRYP 653
SQ + L V P
Sbjct: 939 SQEMRLSVNTKP 950
Score = 44.7 bits (104), Expect = 4e-04
Identities = 89/388 (22%), Positives = 132/388 (34%), Gaps = 90/388 (23%)
Query: 321 LSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGR------VHTGL-------------Y 361
L+C A PP W R Q P + AGR +G+ Y
Sbjct: 688 LACRATGRPPPTVTWRRGDGQ----PLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPY 743
Query: 362 TCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGP 421
C ARN + + + + +T + PP+ + S V +L P LP L
Sbjct: 744 VCEARNVFGKVQAEARLIVTGHAPPQ------IASSAPTVRVLEGQPVSLPCIVLA---- 793
Query: 422 QGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPAL-CTVMLWEPLGRPTCWSTAT 480
G P W LP GS +H A +L L E GR +C +T T
Sbjct: 794 ---GRPLPER-HWLKDGRPLPPGS------RHSIRADGSLHLDRALQEHAGRYSCVATNT 843
Query: 481 MGDQF--IMLSCEWP------------------------GGEPPATLGWLDE-----QQQ 509
G Q + L + P G P T+ W E +
Sbjct: 844 AGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRG 903
Query: 510 PLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEA-PQLDVAEPR---- 564
P S + + Q AG + C T+ + L + P++ + R
Sbjct: 904 PHYNVSKEGTLLIAQPSAQDAGA-YVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNANV 962
Query: 565 ---VSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDA 621
V+ G E L+C +G PP L+ + V P T+ + L P G+ +
Sbjct: 963 PLQVTAKAGEEVTLDCEAKGSPPP--LVTWTKDSRPVPPITNRYGLLPSGSLRLAQVQVG 1020
Query: 622 DPAHHRGTYQCVARNAVGNSSQSVLLEV 649
D H Y+C A N G++S +L V
Sbjct: 1021 DSGH----YECTASNPAGSASHRYVLGV 1044
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 62.8 bits (151), Expect = 1e-09
Identities = 161/704 (22%), Positives = 253/704 (35%), Gaps = 125/704 (17%)
Query: 150 PQVRLSNPSPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNR 209
PQ+ L EG +V TC + EG+ P+ F W R E +E + + + +
Sbjct: 113 PQIHL------EGNRLVLTC-LAEGSWPLEFKWM----RDDSELTTYSSEYKYIIPSLQK 161
Query: 210 THLGWYMCSASNSVNRLSSDGAFLDVIYLAT-RTCYKKKSVSG-----IRLLDGAGLRR- 262
G+Y C N + L + + V Y+ + ++K+VS + LL R
Sbjct: 162 LDAGFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITSYPRP 221
Query: 263 ----FKE------RGRMASYLS------VFTVAVCGNCELRTV-EADGPDK--PVI---- 299
F+E R+A L T + G ++ V E +G +K P I
Sbjct: 222 QVTWFREGHKIIPSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSI 281
Query: 300 --------TMEPLGLTEEGFWA--SEREEVTLSCLAASNPPSHY--VWLRDHTQVHTG-- 345
TM P + G + + E TL C+A++ P W R+ ++ +G
Sbjct: 282 ARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRITSGLH 341
Query: 346 ---PTYVIARAGRVHTGLYTC---LARNSYLDTRTQTTVQLTIYYPP--EGQPSCAVHPS 397
I+ TG Y C L +++ R T L I PP +P +
Sbjct: 342 SFGRRLTISNPTSADTGPYVCEAALPGSAFEPARA--TAFLFIIEPPYFTAEPESRISAE 399
Query: 398 PEAVTLLCAWPGGLPPAQLQWEGP-------QGPGPTAPSNVTWSHAAAQLPSGSVFTCT 450
E + G+P LQW Q P ++ + +F C
Sbjct: 400 VEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCF 459
Query: 451 GQ--------HPALAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLG 502
H L + V P+ +T T G I L CE G PA +
Sbjct: 460 ASNEGGEIQTHTYLDVTNIAPVFTQRPVD-----TTVTDGMTAI-LRCEVSGAPKPA-IT 512
Query: 503 WLDEQQQPLGGSSSSMAVHLLQAQ---------EDLAGREFTCRGTHLLRTPDPHCHLQL 553
W E GS LL++ +D +TC + + + L +
Sbjct: 513 WKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGN--YTCYAANTEGSLNASATLTV 570
Query: 554 EAPQLDVAEPRVSV-LEGGEAWLECSLRGGTPPAQL----LWLGPQQQKVDPGTSGFMLH 608
V P V ++G A L C G T ++ +W TS ++
Sbjct: 571 WNRTSIVHPPEDHVVIKGTTATLHC---GATHDPRVSLRYVWKKDNVALTPSSTSRIVVE 627
Query: 609 PEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYP-APPNVTISRLTYGR 667
+G+ L + D G Y C + GN S+ LEV+ P +P N+ +S
Sbjct: 628 KDGSLLISQTWSGDI----GDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVS--PNSS 681
Query: 668 HRREVQLQWAILGPGN--LTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLGGLDPG 725
H V L W GN + ++V+ L W+ S++ PE G + GL P
Sbjct: 682 HSHAVVLSWVRPFDGNSPILYYIVE-----LSENNSPWKVHLSNVGPEMTGVTVSGLTPA 736
Query: 726 VLYAFRILALNHHTAG----HPSEVKIPADPPFSAYPAVLGAAG 765
Y FR+ A+N G S + +P +PP SA P + A+G
Sbjct: 737 RTYQFRVCAVNEVGRGQYSAETSRLMLPEEPP-SAPPKNIVASG 779
Score = 34.3 bits (77), Expect = 0.51
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 12/92 (13%)
Query: 671 EVQLQWAILGPGNL--TGFLVQRKASALGPGAGAWETAASDIEPESRGRRLG--GLDPGV 726
E+ LQW G+ TG++++ + S G W+ DI + L L GV
Sbjct: 1917 ELTLQWTEGHSGDTPTTGYVIEARPS----DEGLWDMFVKDIPRSATSYTLSLDKLRQGV 1972
Query: 727 LYAFRILALNHHTAGHPSE----VKIPADPPF 754
Y FR++A+N G PS V + PF
Sbjct: 1973 TYEFRVVAVNEAGYGEPSNPSTAVSAQVEAPF 2004
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 61.6 bits (148), Expect = 3e-09
Identities = 98/429 (22%), Positives = 158/429 (36%), Gaps = 88/429 (20%)
Query: 291 ADGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVI 350
A P P +M P+ + +E E + L+C+ + W H + + P++
Sbjct: 2717 AGSPSAPGSSM-PIRIESSSSHVAEGETLDLNCVVPGQAHAQVTW---HKRGGSLPSHHQ 2772
Query: 351 ARAGRVH--------TGLYTCLARNSY--LDTRTQTTVQLT----IYYP-PEGQPSCAVH 395
R R+ +G Y C S L+ T++ + ++ P P G P +
Sbjct: 2773 TRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIE 2832
Query: 396 PSPEAVT------LLCAWPG------------GLPPAQLQWEGPQ------GPGPTAPSN 431
PS V L C PG G PA+ Q GP P + +
Sbjct: 2833 PSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYS 2892
Query: 432 VTWSHAAAQLPSGSVFTCTGQHPALAP-PALCTVMLWEPLGRPTCWSTATMGDQFIMLSC 490
+ ++ L + + T P P P L +P+ S T G Q + L+C
Sbjct: 2893 CQVTGSSGTLEASVLVTIEPSSPGPIPAPGLA-----QPIYIEASSSHVTEG-QTLDLNC 2946
Query: 491 EWPGGEPPATLGWLDEQQQPLGGS--------SSSMAVHLLQAQEDLAGREFTCRGTH-- 540
PG + A + W GGS S + +HL+ + E+ CR
Sbjct: 2947 VVPG-QAHAQVTWYKR-----GGSLPARHQTHGSQLRLHLVSPADS---GEYVCRAASGP 2997
Query: 541 ---------LLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWL 591
+ P +L +P + + P +V +G +A +C + G P L W
Sbjct: 2998 GPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWK 3057
Query: 592 GPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLR 651
Q+ D + P G+ + I P++H GTY+CVA NA G + V L V
Sbjct: 3058 TRNQELED----NVHISPNGSIIT--IVGTRPSNH-GTYRCVASNAYGVAQSVVNLSV-- 3108
Query: 652 YPAPPNVTI 660
PP V++
Sbjct: 3109 -HGPPTVSV 3116
Score = 60.5 bits (145), Expect = 7e-09
Identities = 137/615 (22%), Positives = 208/615 (33%), Gaps = 104/615 (16%)
Query: 118 GHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSK--------PQVRLSNPSPV--EGASVVA 167
G ++C+ G + A+++ V VP S+ P + + PS +G
Sbjct: 2987 GEYVCRAASGPGPEQEASFT-----VTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASF 3041
Query: 168 TCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASN------ 221
C + +G P++ W+ R + + + ++ G Y C ASN
Sbjct: 3042 KCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQ 3101
Query: 222 SVNRLSSDG-----------AFLDVIYLATRTCYK----KKSVSGIRLLDGAGLRRFKER 266
SV LS G ++ V T C + S R+ +
Sbjct: 3102 SVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTY 3161
Query: 267 GRMASYL----------SVFTVAVCGNCELRTVE----------ADGPDKPVITMEPLGL 306
G M S+ T L T + A P P + E L
Sbjct: 3162 GLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAEL 3221
Query: 307 TEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVH-----TGPTYVIARAGRVHTGLY 361
T E TL C A +P W + + + G T +I R + +G Y
Sbjct: 3222 TVEA-----GHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQY 3276
Query: 362 TCLARNSYLDTRTQTTVQLTIYYPPEGQ--PSCAVHPSPEAVTLLCAWPGGLPPAQLQWE 419
C A + + T+ L + PP P A + E V L C G PP QW
Sbjct: 3277 ICNATSPA--GHAEATIILHVESPPYATTVPEHASVQAGETVQLQCL-AHGTPPLTFQWS 3333
Query: 420 --GPQGPG-PTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGR---- 472
G PG TA + + AA SG + C + + A +++ P G
Sbjct: 3334 RVGSSLPGRATARNELLHFERAAPEDSGR-YRCRVTNKVGSAEAFAQLLVQGPPGSLPAT 3392
Query: 473 -------PTCWSTATMGDQFIMLSCEWPGGEPP---ATLGWLDEQQQPLGGSSSSMAVHL 522
PT T + + I S E+ P L W E Q G S V
Sbjct: 3393 SIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLR 3452
Query: 523 LQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGG 582
+Q + +C+GT++ + P Q A + A P SVL ++ + G
Sbjct: 3453 IQNLDQ------SCQGTYICQAHGPWGKAQASAQLVIQALP--SVLINIRTSVQTVVVGH 3504
Query: 583 TPPAQLLWLGPQQQKVDPGTSGFMLHP----EGAQLRLGIYDADPAHHRGTYQCVARNAV 638
+ L LG + +V G L P G +R+ + A G Y+C A NA
Sbjct: 3505 AVEFECLALGDPKPQVTWSKVGGHLRPGIVQSGGVVRIAHVELADA---GQYRCTATNAA 3561
Query: 639 GNSSQSVLLEVLRYP 653
G + VLL V P
Sbjct: 3562 GTTQSHVLLLVQALP 3576
Score = 49.3 bits (116), Expect = 2e-05
Identities = 107/475 (22%), Positives = 170/475 (35%), Gaps = 90/475 (18%)
Query: 306 LTEEGFWASEREEVTLSCLAASNPPSHYVWL-----------RDHTQVHTGPTYVIARAG 354
L E W + VTL C++A P S W R + + + I+ A
Sbjct: 3117 LPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAK 3176
Query: 355 RVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAV------TLLCAWP 408
G Y CLA+N+ + Q V + G P + V TL C+
Sbjct: 3177 PSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSAT 3236
Query: 409 GGLPPAQLQWEGPQGPGPTAPSNVTWSH----------AAAQLPSGSVFTCTGQHPALAP 458
G P + W + P P W H AQ SG + C PA
Sbjct: 3237 GS-PAPTIHWSKLRSPLP-------WQHRLEGDTLIIPRVAQQDSGQ-YICNATSPAGHA 3287
Query: 459 PALCTVMLWEPLGRPTCWSTATM-GDQFIMLSCEWPGGEPPATLGWLD-EQQQPLGGSSS 516
A + + P T A++ + + L C G PP T W P ++
Sbjct: 3288 EATIILHVESPPYATTVPEHASVQAGETVQLQC-LAHGTPPLTFQWSRVGSSLPGRATAR 3346
Query: 517 SMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLE 576
+ +H +A + +GR + CR T+ + + + L ++ P + P S+ G ++
Sbjct: 3347 NELLHFERAAPEDSGR-YRCRVTNKVGSAEAFAQLLVQGPPGSL--PATSIPAGSTPTVQ 3403
Query: 577 CSLRGGTPPAQLLWLGPQQQ--KVDPGTSGFMLH--PEGAQLRLG---------IYDADP 623
TP + +G + P G L EG QL G I + D
Sbjct: 3404 V-----TPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQ 3458
Query: 624 AHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQLQWAILGPGN 683
+ +GTY C A G + S L + A P+V I+ R VQ
Sbjct: 3459 S-CQGTYICQAHGPWGKAQASAQLVI---QALPSVLIN------IRTSVQTV-------- 3500
Query: 684 LTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLGG-LDPGVLYAFRILALNH 737
+ G V+ + ALG D +P+ ++GG L PG++ + ++ + H
Sbjct: 3501 VVGHAVEFECLALG-----------DPKPQVTWSKVGGHLRPGIVQSGGVVRIAH 3544
Score = 45.4 bits (106), Expect = 2e-04
Identities = 79/373 (21%), Positives = 119/373 (31%), Gaps = 44/373 (11%)
Query: 320 TLSCLAASNPPSHYVWLRDH--------TQVHTGPTYVIARAGRVHTGLYTCLARNSYLD 371
+L C + +PP ++ W R+ Q H G G+Y C RN +
Sbjct: 1695 SLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICTCRNLHQS 1754
Query: 372 TRTQTTVQLT------IYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQW---EGPQ 422
++ + +T I E Q S +V P + VT +C P L W +
Sbjct: 1755 NTSRAELLVTEAPSKPITVTVEEQRSQSVRPGAD-VTFICTAKSKSPAYTLVWTRLHNGK 1813
Query: 423 GPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTV------MLWEPLGRPTCW 476
P N + QL + CTG + T+ L P+
Sbjct: 1814 LPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPP 1873
Query: 477 STATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVH----LLQAQEDLAGR 532
Q C G P TL W P G + +H L A E
Sbjct: 1874 QLTVQPGQLAEFRCS-ATGSPTPTLEWTG---GPGGQLPAKAQIHGGILRLPAVEPTDQA 1929
Query: 533 EFTCRGTHLLRTPDPHCHLQLE---APQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLL 589
++ CR L + P++ V+ R V G L C G P A +
Sbjct: 1930 QYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCR-AAGVPSATIT 1988
Query: 590 WLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEV 649
W + + G+ E + + A G Y CVA + G + + + V
Sbjct: 1989 W------RKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVV 2042
Query: 650 LRY--PAPPNVTI 660
L +PP V I
Sbjct: 2043 LSASDASPPPVKI 2055
Score = 38.5 bits (88), Expect = 0.027
Identities = 139/637 (21%), Positives = 216/637 (33%), Gaps = 134/637 (21%)
Query: 103 RNSSLVLGELHEGARGHFLCQVLHVAGGQLHA-------AYSHLTLAVLVPVSKPQVRL- 154
R S L L + G ++C+V+ + G L A A + V P P +R+
Sbjct: 2774 RGSRLRLHHVSPADSGEYVCRVMG-SSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIE 2832
Query: 155 -SNPSPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLG 213
S+ EG ++ C V G W R G A V PL +L+ V+ G
Sbjct: 2833 PSSSRVAEGQTLDLKCVV-PGQAHAQVTWHKRG--GNLPARHQVHGPLLRLNQVSPADSG 2889
Query: 214 WYMCSASNSVNRL----------SSDG-----AFLDVIYLATRTCYKKKSVSGIRLLD-- 256
Y C + S L SS G IY+ + + V+ + LD
Sbjct: 2890 EYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSH----VTEGQTLDLN 2945
Query: 257 -------GAGLRRFKERGRMAS---------YLSVFTVAVCGNCELRTVEADGPDK---- 296
A + +K G + + L + + A G R GP++
Sbjct: 2946 CVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASF 3005
Query: 297 ----------------PVITMEPLGLTEEGFWASEREEVTLSCLAASN-PPSHYVW---- 335
PVI+++P T + ++ + CL P W
Sbjct: 3006 TVTVPPSEGSSYRLRSPVISIDPPSST-----VQQGQDASFKCLIHDGAAPISLEWKTRN 3060
Query: 336 --LRDHTQVH-TGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSC 392
L D+ + G I + G Y C+A N+Y Q+ V L+++ G P+
Sbjct: 3061 QELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAY--GVAQSVVNLSVH----GPPTV 3114
Query: 393 AVHPS-------PEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTW----SHAAAQL 441
+V P +AVTL C G P + +W P T+ SHA Q+
Sbjct: 3115 SVLPEGPVWVKVGKAVTLECV-SAGEPRSSARWTRISST-PAKLEQRTYGLMDSHAVLQI 3172
Query: 442 PSGSVFTCTGQHPALAPPALCTVMLWEPL---------GRPTCWS----TATMGDQFIML 488
S + G + LA AL T + G P + L
Sbjct: 3173 SSAKP-SDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATL 3231
Query: 489 SCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLL---QAQEDLAGREFTCRGTHLLRTP 545
C G P T+ W + + PL L+ AQ+D ++ C T
Sbjct: 3232 RCS-ATGSPAPTIHW-SKLRSPLPWQHRLEGDTLIIPRVAQQD--SGQYICNATSPAGHA 3287
Query: 546 DPHCHLQLEAPQLDVAEPRVSVLEGGE-AWLECSLRGGTPPAQLLWLGPQQQKVDPGTSG 604
+ L +E+P P + ++ GE L+C L GTPP W +V G
Sbjct: 3288 EATIILHVESPPYATTVPEHASVQAGETVQLQC-LAHGTPPLTFQW-----SRVGSSLPG 3341
Query: 605 FMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNS 641
A+ L ++ G Y+C N VG++
Sbjct: 3342 ----RATARNELLHFERAAPEDSGRYRCRVTNKVGSA 3374
Score = 37.0 bits (84), Expect = 0.078
Identities = 64/286 (22%), Positives = 105/286 (36%), Gaps = 38/286 (13%)
Query: 387 EGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQL----- 441
E P+ ++ P + +L C G PP W + G PS H ++L
Sbjct: 1680 EVHPARSIVPQGGSHSLRCQVSGS-PPHYFYWS--REDGRPVPSGTQQRHQGSELHFPSV 1736
Query: 442 -PSGS-VFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTATMGDQFIM------LSCEWP 493
PS + V+ CT ++ + + +++ E +P + Q + C
Sbjct: 1737 QPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAK 1796
Query: 494 GGEPPATLGW--LDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHC-- 549
P TL W L + P + + + Q AG + C G+++
Sbjct: 1797 SKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGT-YVCTGSNMFAMDQGTATL 1855
Query: 550 HLQ----LEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGF 605
H+Q L AP + + P+++V G A CS G+P L W G G G
Sbjct: 1856 HVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSAT-GSPTPTLEWTG--------GPGGQ 1906
Query: 606 MLHPEGAQLRLGI--YDADPAHHRGTYQCVARNAVGNSSQSVLLEV 649
+ P AQ+ GI A + Y C A ++ G +L V
Sbjct: 1907 L--PAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHV 1950
Score = 33.5 bits (75), Expect = 0.87
Identities = 27/127 (21%), Positives = 46/127 (36%), Gaps = 18/127 (14%)
Query: 102 LRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNP--SP 159
L +L++ + + G ++C AG H +++ V P + P +
Sbjct: 3258 LEGDTLIIPRVAQQDSGQYICNATSPAG--------HAEATIILHVESPPYATTVPEHAS 3309
Query: 160 VEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVG---VTEPLFQLDPVNRTHLGWYM 216
V+ V + GT P+TF W +G +L G L + G Y
Sbjct: 3310 VQAGETVQLQCLAHGTPPLTFQWSR-----VGSSLPGRATARNELLHFERAAPEDSGRYR 3364
Query: 217 CSASNSV 223
C +N V
Sbjct: 3365 CRVTNKV 3371
Score = 31.6 bits (70), Expect = 3.3
Identities = 50/236 (21%), Positives = 73/236 (30%), Gaps = 48/236 (20%)
Query: 288 TVEADGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVW------LRDHTQ 341
T++ G P+ + E + + L+C+ A P + W L Q
Sbjct: 2616 TIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQ 2675
Query: 342 VHTGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSP--- 398
H G + + +G Y C A N+ + ++ P G PS P
Sbjct: 2676 TH-GSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVS---PSAGSPSAPGSSMPIRI 2731
Query: 399 ----------EAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQLPS----- 443
E + L C PG A + VTW LPS
Sbjct: 2732 ESSSSHVAEGETLDLNCVVPG-----------------QAHAQVTWHKRGGSLPSHHQTR 2774
Query: 444 GSVFTCTGQHPALAPPALCTVM-LWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPP 498
GS PA + +C VM PL + G + + PGG PP
Sbjct: 2775 GSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPA--PGGAPP 2828
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 60.8 bits (146), Expect = 5e-09
Identities = 109/471 (23%), Positives = 175/471 (37%), Gaps = 63/471 (13%)
Query: 318 EVTLSCLAASNPPSHYVWLRDHTQVHTGPTYV--------IARAGRVHTGLYTCLARNSY 369
++ L C+A+ P W + + + I +G Y CLA N
Sbjct: 274 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 333
Query: 370 LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAP 429
R +V++ +P + E L+C G P +QW P +AP
Sbjct: 334 GSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCR-ANGNPKPTVQWMVNGEPLQSAP 392
Query: 430 SNVTWSHAA-------AQLPSGSVFTC--TGQHPALAPPALCTVMLWEP-LGRPTCWSTA 479
N A Q+ S +V+ C + +H L A +V+ P + P
Sbjct: 393 PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIR 452
Query: 480 TMGDQFIMLSCEWPGGEPPATLGWLDEQQQPL--GGS-----SSSMAVHLLQAQEDLAGR 532
+ L C + G P TL W Q GG+ + S+ + +++ ++
Sbjct: 453 VILYNRTRLDCPF-FGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI-- 509
Query: 533 EFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEA-WLECSLRGGTPPAQLL-- 589
+TC T++L + L+++ P P V G LEC ++ P +L
Sbjct: 510 -YTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHD-PSLKLTVS 567
Query: 590 WLGPQQQKVDPGTSGFMLHPEGAQLRL-GIYDADPAHHRGTYQCVARNAVGNSSQSVLLE 648
WL + P G + E L + G+ + D +G+Y CVA + L
Sbjct: 568 WLKDDE----PLYIGNRMKKEDDSLTIFGVAERD----QGSYTCVASTELDQDLAKAYLT 619
Query: 649 VLRYPAPPNVTISRLTYGRH------------RREVQLQWAILGPGN---LTGFLVQRKA 693
VL A P ++ L GR R V+L W I G N +T ++VQ +
Sbjct: 620 VLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW-IPGDANNSPITDYVVQFEE 678
Query: 694 SALGPGAGAWETAASDIEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPS 744
PG W + P S + L P V Y FR++A+N + HPS
Sbjct: 679 DQFQPGV--WHDHSK--YPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPS 725
Score = 37.0 bits (84), Expect = 0.078
Identities = 33/139 (23%), Positives = 50/139 (35%), Gaps = 19/139 (13%)
Query: 316 REEVTLSCLAASNPPSHYVWLRD------------HTQVHTGPTYVIARAG---RVHTGL 360
R+ + + C A NP + W R+ + +G + R+G + G
Sbjct: 50 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 109
Query: 361 YTCLARNSY---LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQ 417
Y C ARN + L R + V + +P E V +TL C P GLP +
Sbjct: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEG-APLTLQCNPPPGLPSPVIF 168
Query: 418 WEGPQGPGPTAPSNVTWSH 436
W T V+ H
Sbjct: 169 WMSSSMEPITQDKRVSQGH 187
>gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
Length = 1240
Score = 60.8 bits (146), Expect = 5e-09
Identities = 109/471 (23%), Positives = 175/471 (37%), Gaps = 63/471 (13%)
Query: 318 EVTLSCLAASNPPSHYVWLRDHTQVHTGPTYV--------IARAGRVHTGLYTCLARNSY 369
++ L C+A+ P W + + + I +G Y CLA N
Sbjct: 263 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 322
Query: 370 LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAP 429
R +V++ +P + E L+C G P +QW P +AP
Sbjct: 323 GSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCR-ANGNPKPTVQWMVNGEPLQSAP 381
Query: 430 SNVTWSHAA-------AQLPSGSVFTC--TGQHPALAPPALCTVMLWEP-LGRPTCWSTA 479
N A Q+ S +V+ C + +H L A +V+ P + P
Sbjct: 382 PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIR 441
Query: 480 TMGDQFIMLSCEWPGGEPPATLGWLDEQQQPL--GGS-----SSSMAVHLLQAQEDLAGR 532
+ L C + G P TL W Q GG+ + S+ + +++ ++
Sbjct: 442 VILYNRTRLDCPF-FGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI-- 498
Query: 533 EFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEA-WLECSLRGGTPPAQLL-- 589
+TC T++L + L+++ P P V G LEC ++ P +L
Sbjct: 499 -YTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHD-PSLKLTVS 556
Query: 590 WLGPQQQKVDPGTSGFMLHPEGAQLRL-GIYDADPAHHRGTYQCVARNAVGNSSQSVLLE 648
WL + P G + E L + G+ + D +G+Y CVA + L
Sbjct: 557 WLKDDE----PLYIGNRMKKEDDSLTIFGVAERD----QGSYTCVASTELDQDLAKAYLT 608
Query: 649 VLRYPAPPNVTISRLTYGRH------------RREVQLQWAILGPGN---LTGFLVQRKA 693
VL A P ++ L GR R V+L W I G N +T ++VQ +
Sbjct: 609 VLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW-IPGDANNSPITDYVVQFEE 667
Query: 694 SALGPGAGAWETAASDIEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPS 744
PG W + P S + L P V Y FR++A+N + HPS
Sbjct: 668 DQFQPGV--WHDHSK--YPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPS 714
Score = 39.3 bits (90), Expect = 0.016
Identities = 91/431 (21%), Positives = 142/431 (32%), Gaps = 71/431 (16%)
Query: 316 REEVTLSCLAASNPPSHYVWLRD------------HTQVHTGPTYVIARAG---RVHTGL 360
R+ + + C A NP + W R+ + +G + R+G + G
Sbjct: 56 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 115
Query: 361 YTCLARNSY---LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQ 417
Y C ARN + L R + V + +P E V +TL C P GLP +
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEG-APLTLQCNPPPGLPSPVIF 174
Query: 418 WEGPQGPGPTAPSNVTWSHAAAQLPSGSV---------------FTCTGQHP-------- 454
W T V+ H S + FT T Q
Sbjct: 175 WMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVL 234
Query: 455 ALAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWL----DEQQQP 510
A T P G T S + ++L C G P + W D
Sbjct: 235 TTRGVAERTPSFMYPQG--TASSQMVLRGMDLLLEC-IASGVPTPDIAWYKKGGDLPSDK 291
Query: 511 LGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEG 570
+ + A+ + E+ +G E+ C ++ + + ++++A + EP+ +L
Sbjct: 292 AKFENFNKALRITNVSEEDSG-EYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAP 350
Query: 571 GEAWLECSLRGGTPPAQLLWL--GPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRG 628
GE G P + W+ G Q P + G + I+ R
Sbjct: 351 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPN---REVAGDTI---IFRDTQISSRA 404
Query: 629 TYQCVARNAVGNSSQSVLLEVLRYP----APPNVTISRLTYGRHRREV--------QLQW 676
YQC N G + + VL P +P N I + Y R R + L+W
Sbjct: 405 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRW 464
Query: 677 AILGPG-NLTG 686
G G NL G
Sbjct: 465 FKNGQGSNLDG 475
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 59.3 bits (142), Expect = 1e-08
Identities = 107/460 (23%), Positives = 175/460 (38%), Gaps = 56/460 (12%)
Query: 318 EVTLSCLAASNPPSHYVWLRDHTQVHTGPTYV--------IARAGRVHTGLYTCLARNSY 369
++ L C+A+ P W + + + I +G Y CLA N
Sbjct: 274 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 333
Query: 370 LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAP 429
R +V++ +P + E L+C G P +QW P +AP
Sbjct: 334 GSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCR-ANGNPKPTVQWMVNGEPLQSAP 392
Query: 430 SNVTWSHAA-------AQLPSGSVFTC--TGQHPALAPPALCTVMLWEP-LGRPTCWSTA 479
N A Q+ S +V+ C + +H L A +V+ P + P
Sbjct: 393 PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIR 452
Query: 480 TMGDQFIMLSCEWPGGEPPATLGWLDEQQQPL--GGS-----SSSMAVHLLQAQEDLAGR 532
+ L C + G P TL W Q GG+ + S+ + +++ ++
Sbjct: 453 VILYNRTRLDCPF-FGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI-- 509
Query: 533 EFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEA-WLECSLRGGTPPAQLL-- 589
+TC T++L + L+++ P P V G LEC ++ P +L
Sbjct: 510 -YTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHD-PSLKLTVS 567
Query: 590 WLGPQQQKVDPGTSGFMLHPEGAQLRL-GIYDADPAHHRGTYQCVARNAVGNSSQSVLLE 648
WL + P G + E L + G+ + D +G+Y CVA + L
Sbjct: 568 WLKDDE----PLYIGNRMKKEDDSLTIFGVAERD----QGSYTCVASTELDQDLAKAYLT 619
Query: 649 VLRYP-APPNVTISRLTYGRHRREVQLQWAILGPGN---LTGFLVQRKASALGPGAGAWE 704
VL P P ++ ++ L R V+L W I G N +T ++VQ + PG W
Sbjct: 620 VLGRPDRPRDLELTDLA----ERSVRLTW-IPGDANNSPITDYVVQFEEDQFQPGV--WH 672
Query: 705 TAASDIEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPS 744
+ P S + L P V Y FR++A+N + HPS
Sbjct: 673 DHSK--YPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPS 710
Score = 37.0 bits (84), Expect = 0.078
Identities = 33/139 (23%), Positives = 50/139 (35%), Gaps = 19/139 (13%)
Query: 316 REEVTLSCLAASNPPSHYVWLRD------------HTQVHTGPTYVIARAG---RVHTGL 360
R+ + + C A NP + W R+ + +G + R+G + G
Sbjct: 50 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 109
Query: 361 YTCLARNSY---LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQ 417
Y C ARN + L R + V + +P E V +TL C P GLP +
Sbjct: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEG-APLTLQCNPPPGLPSPVIF 168
Query: 418 WEGPQGPGPTAPSNVTWSH 436
W T V+ H
Sbjct: 169 WMSSSMEPITQDKRVSQGH 187
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 59.3 bits (142), Expect = 1e-08
Identities = 107/460 (23%), Positives = 175/460 (38%), Gaps = 56/460 (12%)
Query: 318 EVTLSCLAASNPPSHYVWLRDHTQVHTGPTYV--------IARAGRVHTGLYTCLARNSY 369
++ L C+A+ P W + + + I +G Y CLA N
Sbjct: 274 DLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKM 333
Query: 370 LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAP 429
R +V++ +P + E L+C G P +QW P +AP
Sbjct: 334 GSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCR-ANGNPKPTVQWMVNGEPLQSAP 392
Query: 430 SNVTWSHAA-------AQLPSGSVFTC--TGQHPALAPPALCTVMLWEP-LGRPTCWSTA 479
N A Q+ S +V+ C + +H L A +V+ P + P
Sbjct: 393 PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIR 452
Query: 480 TMGDQFIMLSCEWPGGEPPATLGWLDEQQQPL--GGS-----SSSMAVHLLQAQEDLAGR 532
+ L C + G P TL W Q GG+ + S+ + +++ ++
Sbjct: 453 VILYNRTRLDCPF-FGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGI-- 509
Query: 533 EFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEA-WLECSLRGGTPPAQLL-- 589
+TC T++L + L+++ P P V G LEC ++ P +L
Sbjct: 510 -YTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHD-PSLKLTVS 567
Query: 590 WLGPQQQKVDPGTSGFMLHPEGAQLRL-GIYDADPAHHRGTYQCVARNAVGNSSQSVLLE 648
WL + P G + E L + G+ + D +G+Y CVA + L
Sbjct: 568 WLKDDE----PLYIGNRMKKEDDSLTIFGVAERD----QGSYTCVASTELDQDLAKAYLT 619
Query: 649 VLRYP-APPNVTISRLTYGRHRREVQLQWAILGPGN---LTGFLVQRKASALGPGAGAWE 704
VL P P ++ ++ L R V+L W I G N +T ++VQ + PG W
Sbjct: 620 VLGRPDRPRDLELTDLA----ERSVRLTW-IPGDANNSPITDYVVQFEEDQFQPGV--WH 672
Query: 705 TAASDIEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPS 744
+ P S + L P V Y FR++A+N + HPS
Sbjct: 673 DHSK--YPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPS 710
Score = 37.0 bits (84), Expect = 0.078
Identities = 33/139 (23%), Positives = 50/139 (35%), Gaps = 19/139 (13%)
Query: 316 REEVTLSCLAASNPPSHYVWLRD------------HTQVHTGPTYVIARAG---RVHTGL 360
R+ + + C A NP + W R+ + +G + R+G + G
Sbjct: 50 RDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 109
Query: 361 YTCLARNSY---LDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQ 417
Y C ARN + L R + V + +P E V +TL C P GLP +
Sbjct: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEG-APLTLQCNPPPGLPSPVIF 168
Query: 418 WEGPQGPGPTAPSNVTWSH 436
W T V+ H
Sbjct: 169 WMSSSMEPITQDKRVSQGH 187
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 59.3 bits (142), Expect = 1e-08
Identities = 67/229 (29%), Positives = 89/229 (38%), Gaps = 27/229 (11%)
Query: 535 TCRGTHLLRTPDPHCHLQLEAPQLDVAEP--RVSVLEGGEAWLECSLRGGTPPAQLLWLG 592
+CR T L L + +L++ EP +V G +A C+L P + W
Sbjct: 4409 SCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWY- 4467
Query: 593 PQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRY 652
V P S + + +G+ L + A P HH G R+AV S L VL
Sbjct: 4468 INGAAVQPDDSDWTVTADGSHHALLLRSAQP-HHAGEVTFACRDAVA----SARLTVLGL 4522
Query: 653 PAPPNVTISRLTYGRHRREVQLQWAIL---GPGNLTGFLVQRKASALGPGAGAWETAASD 709
P PP R V L WA G G L G+ V+ K A G E
Sbjct: 4523 PDPPE---DAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPG- 4578
Query: 710 IEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPSEVKIP-----ADPP 753
PE + GL PG Y FR+ A+ AG P V +P A+PP
Sbjct: 4579 --PECV---VDGLAPGETYRFRVAAVGPVGAGEP--VHLPQTVRLAEPP 4620
Score = 38.1 bits (87), Expect = 0.035
Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 12/86 (13%)
Query: 295 DKPVITMEPLGLTE-EGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARA 353
D+P + P LT + F S ++ TLSC NP W +D V G + +A+
Sbjct: 2 DQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQD 61
Query: 354 GRVH-----------TGLYTCLARNS 368
G ++ +G Y C ARN+
Sbjct: 62 GDLYRLTILDLALGDSGQYVCRARNA 87
Score = 38.1 bits (87), Expect = 0.035
Identities = 50/203 (24%), Positives = 80/203 (39%), Gaps = 22/203 (10%)
Query: 488 LSCEWPGGEPPATLGWLDEQQQPLGGSSSSMA----VHLLQAQEDLAGR--EFTCRGTHL 541
LSC+ G P + W +QQ G+ +A ++ L + G ++ CR +
Sbjct: 29 LSCQIVGNPTPQ-VSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNA 87
Query: 542 LRTPDPHCHLQLEA--------PQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGP 593
+ LQ++A P + + V EG EA C + GG+P + W
Sbjct: 88 IGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRV-GGSPRPAVSWSKD 146
Query: 594 QQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYP 653
++ +P + G L I A P GTY+ A N +G +S + L V
Sbjct: 147 GRRLGEPDGPRVRVEELGEASALRIRAARP-RDGGTYEVRAENPLGAASAAAALVVDSDA 205
Query: 654 A-----PPNVTISRLTYGRHRRE 671
A P T + L + + RRE
Sbjct: 206 ADTASRPGTSTAALLAHLQRRRE 228
Score = 38.1 bits (87), Expect = 0.035
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 6/113 (5%)
Query: 545 PDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQK----VDP 600
P H QL P++ V +G + G P + WL + ++ + P
Sbjct: 5360 PASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPT-VHWLREEAERGVLWIGP 5418
Query: 601 GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYP 653
T G+ + Q L + D H+GTY C+A NA G + S L V P
Sbjct: 5419 DTPGYTVASSAQQHSLVLLDVG-RQHQGTYTCIASNAAGQALCSASLHVSGLP 5470
Score = 37.0 bits (84), Expect = 0.078
Identities = 43/152 (28%), Positives = 59/152 (38%), Gaps = 7/152 (4%)
Query: 508 QQPLGGSSSSMAVHLLQAQEDLAGREFTCRGT---HLLRTPDPHCHLQLEAPQLDVAEPR 564
+ PLG +S++ A+ + D A R T HL R + A
Sbjct: 187 ENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRT 246
Query: 565 VSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPA 624
+V EG A L C + G P + +W Q V G + L I +
Sbjct: 247 CTVTEGKHARLSCYVTG-EPKPETVWK-KDGQLVTEGRRHVVYEDAQENFVLKILFCKQS 304
Query: 625 HHRGTYQCVARNAVGNSSQSVLLEVLRYPAPP 656
RG Y C A N VG + SVL+ V+R PA P
Sbjct: 305 D-RGLYTCTASNLVGQTYSSVLV-VVREPAVP 334
Score = 36.2 bits (82), Expect = 0.13
Identities = 32/91 (35%), Positives = 43/91 (47%), Gaps = 5/91 (5%)
Query: 560 VAEPRVSVLE-GGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGI 618
+ P+ V+ G +A L C + G P Q+ W QQ V G F L +G RL I
Sbjct: 13 LTRPKAFVVSVGKDATLSCQIVGNPTP-QVSW-EKDQQPVAAGAR-FRLAQDGDLYRLTI 69
Query: 619 YDADPAHHRGTYQCVARNAVGNSSQSVLLEV 649
D G Y C ARNA+G + +V L+V
Sbjct: 70 LDL-ALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 34.7 bits (78), Expect = 0.39
Identities = 37/128 (28%), Positives = 52/128 (40%), Gaps = 24/128 (18%)
Query: 237 YLATRTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDK 296
+LA R ++SG+R D +GL FK G S V T +
Sbjct: 2123 HLAVRGPMHTLTLSGLRPED-SGLMVFKAEGVHTSARLVVT-----------------EL 2164
Query: 297 PVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV 356
PV PL + +E+E+VTL C S P WL+D ++ G T IA G
Sbjct: 2165 PVSFSRPL----QDVVTTEKEKVTLEC-ELSRPNVDVRWLKDGVELRAGKTMAIAAQGAC 2219
Query: 357 HT-GLYTC 363
+ +Y C
Sbjct: 2220 RSLTIYRC 2227
Score = 32.7 bits (73), Expect = 1.5
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 16/79 (20%)
Query: 296 KPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQ---------VHTGP 346
KPV+ ++ L + A ER + L C S+P +H VW +D Q +HT
Sbjct: 2645 KPVVFLKAL----DDLSAEERGTLALQC-EVSDPEAHVVWRKDGVQLGPSDKYDFLHTAG 2699
Query: 347 T--YVIARAGRVHTGLYTC 363
T V+ GLYTC
Sbjct: 2700 TRGLVVHDVSPEDAGLYTC 2718
Score = 32.7 bits (73), Expect = 1.5
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 9/90 (10%)
Query: 565 VSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPA 624
+ VLEGG A L C L P + + + PG + L EGA L L + + P
Sbjct: 3194 LEVLEGGAATLRCVLSSVAAPVKWCY---GNNVLRPGDK-YSLRQEGAMLELVVRNLRP- 3248
Query: 625 HHRGTYQCVARNAVGNSSQSVLLEVLRYPA 654
G Y C + G+ + S L V PA
Sbjct: 3249 QDSGRYSC----SFGDQTTSATLTVTALPA 3274
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 59.3 bits (142), Expect = 1e-08
Identities = 67/229 (29%), Positives = 89/229 (38%), Gaps = 27/229 (11%)
Query: 535 TCRGTHLLRTPDPHCHLQLEAPQLDVAEP--RVSVLEGGEAWLECSLRGGTPPAQLLWLG 592
+CR T L L + +L++ EP +V G +A C+L P + W
Sbjct: 4409 SCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWY- 4467
Query: 593 PQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRY 652
V P S + + +G+ L + A P HH G R+AV S L VL
Sbjct: 4468 INGAAVQPDDSDWTVTADGSHHALLLRSAQP-HHAGEVTFACRDAVA----SARLTVLGL 4522
Query: 653 PAPPNVTISRLTYGRHRREVQLQWAIL---GPGNLTGFLVQRKASALGPGAGAWETAASD 709
P PP R V L WA G G L G+ V+ K A G E
Sbjct: 4523 PDPPE---DAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPG- 4578
Query: 710 IEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPSEVKIP-----ADPP 753
PE + GL PG Y FR+ A+ AG P V +P A+PP
Sbjct: 4579 --PECV---VDGLAPGETYRFRVAAVGPVGAGEP--VHLPQTVRLAEPP 4620
Score = 38.1 bits (87), Expect = 0.035
Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 12/86 (13%)
Query: 295 DKPVITMEPLGLTE-EGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARA 353
D+P + P LT + F S ++ TLSC NP W +D V G + +A+
Sbjct: 2 DQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQD 61
Query: 354 GRVH-----------TGLYTCLARNS 368
G ++ +G Y C ARN+
Sbjct: 62 GDLYRLTILDLALGDSGQYVCRARNA 87
Score = 38.1 bits (87), Expect = 0.035
Identities = 50/203 (24%), Positives = 80/203 (39%), Gaps = 22/203 (10%)
Query: 488 LSCEWPGGEPPATLGWLDEQQQPLGGSSSSMA----VHLLQAQEDLAGR--EFTCRGTHL 541
LSC+ G P + W +QQ G+ +A ++ L + G ++ CR +
Sbjct: 29 LSCQIVGNPTPQ-VSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNA 87
Query: 542 LRTPDPHCHLQLEA--------PQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGP 593
+ LQ++A P + + V EG EA C + GG+P + W
Sbjct: 88 IGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRV-GGSPRPAVSWSKD 146
Query: 594 QQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYP 653
++ +P + G L I A P GTY+ A N +G +S + L V
Sbjct: 147 GRRLGEPDGPRVRVEELGEASALRIRAARP-RDGGTYEVRAENPLGAASAAAALVVDSDA 205
Query: 654 A-----PPNVTISRLTYGRHRRE 671
A P T + L + + RRE
Sbjct: 206 ADTASRPGTSTAALLAHLQRRRE 228
Score = 38.1 bits (87), Expect = 0.035
Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 6/113 (5%)
Query: 545 PDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQK----VDP 600
P H QL P++ V +G + G P + WL + ++ + P
Sbjct: 5360 PASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPT-VHWLREEAERGVLWIGP 5418
Query: 601 GTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYP 653
T G+ + Q L + D H+GTY C+A NA G + S L V P
Sbjct: 5419 DTPGYTVASSAQQHSLVLLDVG-RQHQGTYTCIASNAAGQALCSASLHVSGLP 5470
Score = 37.0 bits (84), Expect = 0.078
Identities = 43/152 (28%), Positives = 59/152 (38%), Gaps = 7/152 (4%)
Query: 508 QQPLGGSSSSMAVHLLQAQEDLAGREFTCRGT---HLLRTPDPHCHLQLEAPQLDVAEPR 564
+ PLG +S++ A+ + D A R T HL R + A
Sbjct: 187 ENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRT 246
Query: 565 VSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPA 624
+V EG A L C + G P + +W Q V G + L I +
Sbjct: 247 CTVTEGKHARLSCYVTG-EPKPETVWK-KDGQLVTEGRRHVVYEDAQENFVLKILFCKQS 304
Query: 625 HHRGTYQCVARNAVGNSSQSVLLEVLRYPAPP 656
RG Y C A N VG + SVL+ V+R PA P
Sbjct: 305 D-RGLYTCTASNLVGQTYSSVLV-VVREPAVP 334
Score = 36.2 bits (82), Expect = 0.13
Identities = 32/91 (35%), Positives = 43/91 (47%), Gaps = 5/91 (5%)
Query: 560 VAEPRVSVLE-GGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGI 618
+ P+ V+ G +A L C + G P Q+ W QQ V G F L +G RL I
Sbjct: 13 LTRPKAFVVSVGKDATLSCQIVGNPTP-QVSW-EKDQQPVAAGAR-FRLAQDGDLYRLTI 69
Query: 619 YDADPAHHRGTYQCVARNAVGNSSQSVLLEV 649
D G Y C ARNA+G + +V L+V
Sbjct: 70 LDL-ALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 34.7 bits (78), Expect = 0.39
Identities = 37/128 (28%), Positives = 52/128 (40%), Gaps = 24/128 (18%)
Query: 237 YLATRTCYKKKSVSGIRLLDGAGLRRFKERGRMASYLSVFTVAVCGNCELRTVEADGPDK 296
+LA R ++SG+R D +GL FK G S V T +
Sbjct: 2123 HLAVRGPMHTLTLSGLRPED-SGLMVFKAEGVHTSARLVVT-----------------EL 2164
Query: 297 PVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRV 356
PV PL + +E+E+VTL C S P WL+D ++ G T IA G
Sbjct: 2165 PVSFSRPL----QDVVTTEKEKVTLEC-ELSRPNVDVRWLKDGVELRAGKTMAIAAQGAC 2219
Query: 357 HT-GLYTC 363
+ +Y C
Sbjct: 2220 RSLTIYRC 2227
Score = 32.7 bits (73), Expect = 1.5
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 16/79 (20%)
Query: 296 KPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQ---------VHTGP 346
KPV+ ++ L + A ER + L C S+P +H VW +D Q +HT
Sbjct: 2645 KPVVFLKAL----DDLSAEERGTLALQC-EVSDPEAHVVWRKDGVQLGPSDKYDFLHTAG 2699
Query: 347 T--YVIARAGRVHTGLYTC 363
T V+ GLYTC
Sbjct: 2700 TRGLVVHDVSPEDAGLYTC 2718
Score = 32.7 bits (73), Expect = 1.5
Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 9/90 (10%)
Query: 565 VSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPA 624
+ VLEGG A L C L P + + + PG + L EGA L L + + P
Sbjct: 3194 LEVLEGGAATLRCVLSSVAAPVKWCY---GNNVLRPGDK-YSLRQEGAMLELVVRNLRP- 3248
Query: 625 HHRGTYQCVARNAVGNSSQSVLLEVLRYPA 654
G Y C + G+ + S L V PA
Sbjct: 3249 QDSGRYSC----SFGDQTTSATLTVTALPA 3274
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 59.3 bits (142), Expect = 1e-08
Identities = 96/395 (24%), Positives = 142/395 (35%), Gaps = 55/395 (13%)
Query: 288 TVEADGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVW--------LRDH 339
TVE P IT EP + V +C A NP +W L D
Sbjct: 225 TVEEFNCQSPRITFEPQDVE-----VPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDD 279
Query: 340 TQVHT--GPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPS 397
T+++ T +I G+Y C+ARNS + +TQ+ + Y +PS + P
Sbjct: 280 TRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSA--MLRYSSLPAKPSFVIQPQ 337
Query: 398 PEAV-----TLLCAWPGGLPPAQLQWEGP-----QGPGPTAPSNVTWSHAAAQLPSGSVF 447
V T L G P + W G A S+ + Q G F
Sbjct: 338 DTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGR-F 396
Query: 448 TCTGQHPALAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLS------CEWPGGEPPATL 501
TC + A +++ P T T DQ ++ CE G PP +
Sbjct: 397 TCHANNSHGTVQAAANIIVQAP-----PQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIV 451
Query: 502 GWLDEQQQPLGGSSSSMAVHLLQ----AQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQ 557
Q P+ G + ++ L+ AQ D ++ C+ L L ++
Sbjct: 452 WTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQG--QYECQAVSSLGVKKVSVQLTVKPKA 509
Query: 558 LDV---AEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQL 614
L V SV G + C +G P + W Q + G F + EG
Sbjct: 510 LAVFTQLPQDTSVEVGKNINISCHAQGEPQPI-ITWNKEGVQITESGK--FHVDDEGT-- 564
Query: 615 RLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEV 649
L IYDA +G Y+CVARN+ G + ++ L V
Sbjct: 565 -LTIYDAG-FPDQGRYECVARNSFGLAVTNMFLTV 597
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 54.7 bits (130), Expect = 4e-07
Identities = 76/324 (23%), Positives = 117/324 (36%), Gaps = 22/324 (6%)
Query: 339 HTQVHTGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSP 398
H Q ++ I RA + G Y C A + R + + +T PP+ P+ V SP
Sbjct: 471 HFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDP-PPQLVPAPNVTVSP 529
Query: 399 EAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAP 458
+L G P L W P + V + SG + T G++ +A
Sbjct: 530 GETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVAS 589
Query: 459 PA--LCTVMLWEPLGRPTCWSTATMGDQF-----IMLSCEWPGGEPPATLGWLDEQQQPL 511
A + +W + S T F + +SC G P + W E Q
Sbjct: 590 NANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCS-ASGYPTPHISWSRESQALQ 648
Query: 512 GGSS---SSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQL-EAPQLDVAEPRVSV 567
S + ++Q ++C+ T+ + T L + P + V V
Sbjct: 649 EDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLV 708
Query: 568 LEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHR 627
G EA L C G PP +++W G +L PEG+ A
Sbjct: 709 AVGEEAVLVCEAS-GVPPPRVIWY--------RGGLEMILAPEGSSSGKLRIPAAQERDA 759
Query: 628 GTYQCVARNAVGNSSQSVLLEVLR 651
GTY C A N +G++S + L V R
Sbjct: 760 GTYTCRAVNELGDASAEIQLAVGR 783
Score = 38.1 bits (87), Expect = 0.035
Identities = 36/99 (36%), Positives = 46/99 (46%), Gaps = 9/99 (9%)
Query: 556 PQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLR 615
PQL V P V+V G A L C + G P L W+ + +V P ++G + L
Sbjct: 517 PQL-VPAPNVTVSPGETAVLSCRVLGEAP-YNLTWV--RDWRVLPASTGRVAQLADLSLE 572
Query: 616 L-GIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYP 653
+ GI D G YQCVA NA G + SV L V P
Sbjct: 573 ISGIIPTDG----GRYQCVASNANGVTRASVWLLVREAP 607
Score = 36.2 bits (82), Expect = 0.13
Identities = 54/238 (22%), Positives = 90/238 (37%), Gaps = 23/238 (9%)
Query: 431 NVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGR--PTCWSTATMGDQFIML 488
N +W A + CT A A +++ +P + P T + G+ + L
Sbjct: 477 NSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAV-L 535
Query: 489 SCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPH 548
SC G E P L W+ + + + +S+ L +++G T G + + +
Sbjct: 536 SCRVLG-EAPYNLTWVRDWR--VLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNAN 592
Query: 549 -------CHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPG 601
L EAPQ+ + +G E + CS G P + W Q +
Sbjct: 593 GVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSA-SGYPTPHISWSRESQALQED- 650
Query: 602 TSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVT 659
S + +G + G+ D G Y C A N VG ++V L Y PP+V+
Sbjct: 651 -SRIHVDAQGTLIIQGVAPEDA----GNYSCQATNEVGTDQETV---TLYYTDPPSVS 700
Score = 36.2 bits (82), Expect = 0.13
Identities = 41/150 (27%), Positives = 60/150 (40%), Gaps = 18/150 (12%)
Query: 314 SEREEVTLSCLAASNPPSHYVW------LRDHTQVHTGP--TYVIARAGRVHTGLYTCLA 365
S+ EV +SC A+ P H W L++ +++H T +I G Y+C A
Sbjct: 619 SQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA 678
Query: 366 RNSYLDTRTQTTVQLTIYY--PPEGQPSCAV--HPSPEAVTLLCAWPGGLPPAQLQWEG- 420
N + T +T +T+YY PP AV E L+C G PP + + G
Sbjct: 679 TNE-VGTDQET---VTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGG 734
Query: 421 -PQGPGPTAPSNVTWSHAAAQLPSGSVFTC 449
P S+ AAQ +TC
Sbjct: 735 LEMILAPEGSSSGKLRIPAAQERDAGTYTC 764
>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
Length = 2986
Score = 53.9 bits (128), Expect = 6e-07
Identities = 55/209 (26%), Positives = 93/209 (44%), Gaps = 25/209 (11%)
Query: 551 LQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGF---ML 607
+Q AP+ V V+ L G L+C + G P + W GP Q +D S +
Sbjct: 2466 IQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPT-ITWKGPDQNILDTDNSSATYTVS 2524
Query: 608 HPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGR 667
+ ++ L I + P G Y C+A N G +S S ++V PA PN I++ R
Sbjct: 2525 SCDSGEITLKICNLMP-QDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQ---ER 2580
Query: 668 HRREVQLQW---AILGPGNLTGFLVQRKASALGPGAGAW-ETAASDIEPESRGRRLGGLD 723
V L+W + G ++G+ V+ + G+ W ++ AS ++ + L
Sbjct: 2581 SCTSVILRWLPPSSTGNCTISGYTVEYREE----GSQIWQQSVASTLDTY---LVIEDLS 2633
Query: 724 PGVLYAFRILALNHHTAGHPSEVKIPADP 752
PG Y FR+ +A +P + +P++P
Sbjct: 2634 PGCPYQFRV------SASNPWGISLPSEP 2656
>gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]
Length = 1289
Score = 53.9 bits (128), Expect = 6e-07
Identities = 55/209 (26%), Positives = 93/209 (44%), Gaps = 25/209 (11%)
Query: 551 LQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGF---ML 607
+Q AP+ V V+ L G L+C + G P + W GP Q +D S +
Sbjct: 769 IQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPT-ITWKGPDQNILDTDNSSATYTVS 827
Query: 608 HPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGR 667
+ ++ L I + P G Y C+A N G +S S ++V PA PN I++ R
Sbjct: 828 SCDSGEITLKICNLMP-QDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQ---ER 883
Query: 668 HRREVQLQW---AILGPGNLTGFLVQRKASALGPGAGAW-ETAASDIEPESRGRRLGGLD 723
V L+W + G ++G+ V+ + G+ W ++ AS ++ + L
Sbjct: 884 SCTSVILRWLPPSSTGNCTISGYTVEYREE----GSQIWQQSVASTLDTY---LVIEDLS 936
Query: 724 PGVLYAFRILALNHHTAGHPSEVKIPADP 752
PG Y FR+ +A +P + +P++P
Sbjct: 937 PGCPYQFRV------SASNPWGISLPSEP 959
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 53.1 bits (126), Expect = 1e-06
Identities = 108/494 (21%), Positives = 179/494 (36%), Gaps = 90/494 (18%)
Query: 317 EEVTLSCLAASNPPSHYV-WLRDHTQVHTGPTYVIARAGRV--------HTGLYTCLARN 367
E L C P + W +D ++ + R G++ G+YTC+ N
Sbjct: 164 EPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTN 223
Query: 368 SYLDTRTQTTVQLTIYYPPE--GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPG 425
+ R +LT++ P +P V EAV C G P ++W+
Sbjct: 224 M-VGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGD-PQPTVRWKKDDADL 281
Query: 426 PTAPSNV----TWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEP---LGRPTCWST 478
P ++ T + C ++ A T+ + P + RP
Sbjct: 282 PRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIV 341
Query: 479 ATMGDQFIMLSCEWPGGEPPAT---------LGWLDEQQQPLGGSSSSMA--VHLLQAQE 527
A + + CE G PA L + ++ QQP S S + + Q
Sbjct: 342 AQ--GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQR 399
Query: 528 DLAG----REFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEG---------GEAW 574
AG + T G+ L + QLE + P +L+G G A
Sbjct: 400 SDAGYYICQALTVAGSILAKA-------QLEVTDVLTDRPPPIILQGPANQTLAVDGTAL 452
Query: 575 LECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLR---LGIYDADPAHHRGTYQ 631
L+C G P + WL ++ PG E L+ L I D GTY
Sbjct: 453 LKCKATGDPLPV-ISWL--KEGFTFPGRDPRATIQEQGTLQIKNLRISDT------GTYT 503
Query: 632 CVARNAVGNSSQSVLLEVLR-------------YPAPPN-VTISRLTYGRHRREVQLQWA 677
CVA ++ G +S S +L+V P PP+ ++ +T + V L W
Sbjct: 504 CVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVT----KNSVTLSWQ 559
Query: 678 ILGPGNL--TGFLVQRKASALGPGAGAWETAASDIEPESRGRRLGGLDPGVLYAFRILAL 735
PG L + ++++ + ++ + +W+T A+ ++ R GL P +Y F + A+
Sbjct: 560 PGTPGTLPASAYIIEAFSQSV---SNSWQTVANHVKTTLYTVR--GLRPNTIYLFMVRAI 614
Query: 736 NHHTAGHPSEVKIP 749
N PS + P
Sbjct: 615 NPQGLSDPSPMSDP 628
Score = 43.5 bits (101), Expect = 8e-04
Identities = 74/317 (23%), Positives = 108/317 (34%), Gaps = 67/317 (21%)
Query: 384 YPPE--GQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQL 441
+PP PS + E TL C G P ++W G + SH L
Sbjct: 45 FPPRIVEHPSDVIVSKGEPTTLNCK-AEGRPTPTIEWY-KDGERVETDKDDPRSHRML-L 101
Query: 442 PSGSVFTCTGQHPALAPPA----LCTVM--LWEPLGRPTCWSTATMGDQF---------- 485
PSGS+F H + P +C L E + R A + D F
Sbjct: 102 PSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVA 161
Query: 486 ----IMLSCEWPGGEPPATLGW------LDEQQQPLGGSSSSMAVHLLQAQEDLAGREFT 535
+L C+ P G P T+ W +D++++ + + + + + AG +T
Sbjct: 162 AGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSD--AGM-YT 218
Query: 536 CRGTHLL--RTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGP 593
C GT+++ R DP E P VLE C ++G P + W
Sbjct: 219 CVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPT-VRW--- 274
Query: 594 QQQKVDPGTSGFMLHPEGAQLRLGIYDADPAH----------HRGTYQCVARNAVGNSSQ 643
+ A L G YD + GTY C+A N VG
Sbjct: 275 --------------KKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEA 320
Query: 644 SVLLEVLRYPAPPNVTI 660
S L V APP +
Sbjct: 321 SATLTV---RAPPQFVV 334
Score = 40.8 bits (94), Expect = 0.005
Identities = 76/374 (20%), Positives = 125/374 (33%), Gaps = 46/374 (12%)
Query: 314 SEREEVTLSCLAASNPPSHYVWLRDHTQVHTGP------------------TYVIARAGR 355
S+ E TL+C A P W +D +V T V R +
Sbjct: 59 SKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSK 118
Query: 356 VHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEG---QPSCAVHPSPEAVTLLCAWPGGLP 412
G Y C+ARN YL L + + P+ V + E L C P G P
Sbjct: 119 PDEGSYVCVARN-YLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHP 177
Query: 413 PAQLQWEGPQGPGPTAPSNVTWSHAAAQLPS-----GSVFTCTGQH---PALAPPALCTV 464
+ W+ + ++ + + ++TC G + + PA TV
Sbjct: 178 EPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTV 237
Query: 465 MLWEP-LGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLL 523
L RP + + ++ + C+ G+P T+ W + G + L
Sbjct: 238 FERPTFLRRPI--NQVVLEEEAVEFRCQ-VQGDPQPTVRWKKDDADLPRGRYDIKDDYTL 294
Query: 524 QAQEDLAGRE--FTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVL-EGGEAWLECSLR 580
+ ++ ++ E + C + + + L + AP V PR ++ +G C +
Sbjct: 295 RIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETK 354
Query: 581 GGTPPAQLLWLGPQQQKVDPG-----TSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVAR 635
G PA Q + P S + P G I +D G Y C A
Sbjct: 355 GNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSD----AGYYICQAL 410
Query: 636 NAVGNSSQSVLLEV 649
G+ LEV
Sbjct: 411 TVAGSILAKAQLEV 424
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,868,531
Number of Sequences: 37866
Number of extensions: 2243343
Number of successful extensions: 9267
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 260
Number of HSP's that attempted gapping in prelim test: 6882
Number of HSP's gapped (non-prelim): 2025
length of query: 859
length of database: 18,247,518
effective HSP length: 111
effective length of query: 748
effective length of database: 14,044,392
effective search space: 10505205216
effective search space used: 10505205216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.