Search of human proteins with 169184031

Search of human proteins with 169184031

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169184031 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
         (261 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169184031 PREDICTED: similar to potassium channel tetramerisa...   541   e-154
gi|169179790 PREDICTED: similar to potassium channel tetramerisa...   541   e-154
gi|169180181 PREDICTED: similar to potassium channel tetramerisa...   539   e-154
gi|39753959 potassium channel tetramerisation domain containing ...   488   e-138
gi|9506651 potassium channel tetramerisation domain containing 5...    90   2e-18
gi|53829365 potassium channel tetramerisation domain containing ...    86   2e-17
gi|169234778 potassium channel tetramerisation domain containing...    76   3e-14
gi|71143104 potassium channel tetramerisation domain containing ...    57   1e-08
gi|142356950 potassium channel tetramerisation domain containing...    57   2e-08
gi|23308551 potassium channel tetramerisation domain containing ...    52   5e-07
gi|13994353 potassium channel tetramerisation domain containing ...    52   7e-07
gi|189571693 potassium channel tetramerisation domain containing...    52   7e-07
gi|189571691 potassium channel tetramerisation domain containing...    52   7e-07
gi|30578412 potassium channel tetramerisation domain containing ...    51   1e-06
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  50   2e-06
gi|46255026 potassium channel tetramerisation domain containing ...    49   3e-06
gi|19923973 potassium channel tetramerisation domain containing ...    48   8e-06
gi|55926200 potassium channel tetramerisation domain containing ...    48   8e-06
gi|38198663 potassium channel tetramerisation domain containing ...    47   2e-05
gi|146198864 potassium channel tetramerisation domain containing...    47   2e-05
gi|45387953 potassium channel tetramerization domain containing ...    46   3e-05
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...    45   5e-05
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       45   6e-05
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       45   6e-05
gi|194018443 potassium channel tetramerisation domain containing...    42   5e-04
gi|194018441 potassium channel tetramerisation domain containing...    42   5e-04
gi|194018439 potassium channel tetramerisation domain containing...    42   5e-04
gi|218505694 potassium channel tetramerisation domain containing...    39   0.006
gi|209969708 potassium channel tetramerisation domain containing...    39   0.006
gi|40217617 potassium channel tetramerisation domain containing ...    39   0.006

>gi|169184031 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score =  541 bits (1395), Expect = e-154
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGNGGLNDDIVLIRDDD 60
           MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGNGGLNDDIVLIRDDD
Sbjct: 1   MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGNGGLNDDIVLIRDDD 60

Query: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF 120
           VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF
Sbjct: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF 120

Query: 121 KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL 180
           KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL
Sbjct: 121 KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL 180

Query: 181 IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF 240
           IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF
Sbjct: 181 IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF 240

Query: 241 KITNLNCCNLAHANLCCANLE 261
           KITNLNCCNLAHANLCCANLE
Sbjct: 241 KITNLNCCNLAHANLCCANLE 261


>gi|169179790 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score =  541 bits (1395), Expect = e-154
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGNGGLNDDIVLIRDDD 60
           MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGNGGLNDDIVLIRDDD
Sbjct: 1   MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGNGGLNDDIVLIRDDD 60

Query: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF 120
           VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF
Sbjct: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF 120

Query: 121 KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL 180
           KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL
Sbjct: 121 KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL 180

Query: 181 IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF 240
           IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF
Sbjct: 181 IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF 240

Query: 241 KITNLNCCNLAHANLCCANLE 261
           KITNLNCCNLAHANLCCANLE
Sbjct: 241 KITNLNCCNLAHANLCCANLE 261


>gi|169180181 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score =  539 bits (1389), Expect = e-154
 Identities = 260/261 (99%), Positives = 260/261 (99%)

Query: 1   MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGNGGLNDDIVLIRDDD 60
           MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNG GGLNDDIVLIRDDD
Sbjct: 1   MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGKGGLNDDIVLIRDDD 60

Query: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF 120
           VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF
Sbjct: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF 120

Query: 121 KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL 180
           KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL
Sbjct: 121 KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL 180

Query: 181 IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF 240
           IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF
Sbjct: 181 IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF 240

Query: 241 KITNLNCCNLAHANLCCANLE 261
           KITNLNCCNLAHANLCCANLE
Sbjct: 241 KITNLNCCNLAHANLCCANLE 261


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score =  488 bits (1256), Expect = e-138
 Identities = 239/261 (91%), Positives = 248/261 (95%)

Query: 1   MRRVTLFLNGSPKNGKVVAAYGTSCDLLSVASSKLGIKATSVYNGNGGLNDDIVLIRDDD 60
           MRRVTLFLNGSPKNGKVVA YGT  DLLSVASSKLGIKATSVYNG GGL DDI LIRDDD
Sbjct: 1   MRRVTLFLNGSPKNGKVVAVYGTLSDLLSVASSKLGIKATSVYNGKGGLIDDIALIRDDD 60

Query: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF 120
           VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTL+VGG+YFTTT STLVNKEPD MLAHMF
Sbjct: 61  VLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMF 120

Query: 121 KDKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSL 180
           KDKGVWGNKQDHRGAFLID+SPEYFEPILNYLRHGQLIVNDGI+LLGVLEEARFFGIDSL
Sbjct: 121 KDKGVWGNKQDHRGAFLIDRSPEYFEPILNYLRHGQLIVNDGINLLGVLEEARFFGIDSL 180

Query: 181 IEHLKVAIKNSQPPEDHLPISRKEFVRCLLATPTKSEMRCQGLNFSGAELSHLDLRYINF 240
           IEHL+VAIKNSQPPEDH PISRKEFVR LLATPTKSE+RCQGLNFSGA+LS LDLRYINF
Sbjct: 181 IEHLEVAIKNSQPPEDHSPISRKEFVRFLLATPTKSELRCQGLNFSGADLSRLDLRYINF 240

Query: 241 KITNLNCCNLAHANLCCANLE 261
           K+ NL+ CNLAHANLCCANLE
Sbjct: 241 KMANLSRCNLAHANLCCANLE 261


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 51/119 (42%), Positives = 71/119 (59%), Gaps = 6/119 (5%)

Query: 85  GFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEY 144
           G  + W+ L+VGG YF TT  TL  ++P   L  + +      + +D  GA+LID+ P Y
Sbjct: 40  GSVSKWVRLNVGGTYFLTTRQTLC-RDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTY 98

Query: 145 FEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKVAI-----KNSQPPEDHL 198
           F P+LNYLRHG+L++N  +   GVLEEA F+ I SLI+ +K  I     K SQ P  H+
Sbjct: 99  FGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQVPVKHV 157


>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 50/115 (43%), Positives = 69/115 (60%), Gaps = 7/115 (6%)

Query: 90  WLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF-KDKGVWGNKQDHRGAFLIDQSPEYFEPI 148
           W+ L+VGG YF TT  TL  +EP   L  +  ++     + +D  GA+LID+ P YF PI
Sbjct: 73  WVRLNVGGTYFVTTRQTL-GREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPI 131

Query: 149 LNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKN-----SQPPEDHL 198
           LNYLRHG+LI+   +   GVLEEA F+ I SL+  +K  I++     SQ P  H+
Sbjct: 132 LNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPVKHV 186


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 45/114 (39%), Positives = 67/114 (58%), Gaps = 6/114 (5%)

Query: 76  DSKPPEGL----LGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQD 131
           ++ PP G      G    W+ L+VGG  F TT  TL  +E    L+ + + + +  ++ D
Sbjct: 14  EAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLC-REQKSFLSRLCQGEELQSDR-D 71

Query: 132 HRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLK 185
             GA+LID+ P YF PILN+LRHG+L+++  +   GVLEEA F+ I  LI  +K
Sbjct: 72  ETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIK 125


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 4/99 (4%)

Query: 88  TDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEP 147
           +D +TL+VGG+ +TT+ +TL +  PD ML  MF  K     K+D +G   ID+  + F  
Sbjct: 2   SDPITLNVGGKLYTTSLATLTSF-PDSMLGAMFSGK--MPTKRDSQGNCFIDRDGKVFRY 58

Query: 148 ILNYLRHGQLIVNDGIDLLGVL-EEARFFGIDSLIEHLK 185
           ILN+LR   L + +    +G+L  EA F+ +  LIE L+
Sbjct: 59  ILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQ 97


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 47/125 (37%), Positives = 61/125 (48%), Gaps = 14/125 (11%)

Query: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPILNYL 152
           L+VGG++ TTT  TL  K P   LA MF          D  G F ID+   YF PIL+YL
Sbjct: 37  LNVGGEFHTTTLGTL-RKFPGSKLAEMFSSLAKAST--DAEGRFFIDRPSTYFRPILDYL 93

Query: 153 RHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQPPEDHLPISRKEFVRCLLAT 212
           R GQ+       +  V  EA+F+ I  L++ L+       P      +SRK+F   LL  
Sbjct: 94  RTGQVPTQ---HIPEVYREAQFYEIKPLVKLLE-----DMPQIFGEQVSRKQF---LLQV 142

Query: 213 PTKSE 217
           P  SE
Sbjct: 143 PGYSE 147


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 42/131 (32%), Positives = 65/131 (49%), Gaps = 14/131 (10%)

Query: 68  EPFIDPQTDSKPPEG-----LLGFHTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKD 122
           + F++P T +    G     L     + + L++GG +FTT  STL   E D MLA MF  
Sbjct: 25  DDFLEPATPTATQAGHALPLLPQEFPEVVPLNIGGAHFTTRLSTLRCYE-DTMLAAMFSG 83

Query: 123 KGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIE 182
           +       D  G + ID+   +F  +LN+LR G L   + +    V +EA+++ I  L+E
Sbjct: 84  RHYIPT--DSEGRYFIDRDGTHFGDVLNFLRSGDLPPRERV--RAVYKEAQYYAIGPLLE 139

Query: 183 HLKVAIKNSQP 193
            L    +N QP
Sbjct: 140 QL----ENMQP 146


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)

Query: 90  WLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPIL 149
           ++ L+VGG  + TT  TL  +  D ML  MF   G      D  G  LID+  ++F  IL
Sbjct: 33  YVKLNVGGALYYTTMQTLTKQ--DTMLKAMFS--GRMEVLTDSEGWILIDRCGKHFGTIL 88

Query: 150 NYLRHGQL-IVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQPPEDHLPI----SRKE 204
           NYLR G + +     ++  +L EA+++ +  L+E  + A++N    E    +    S KE
Sbjct: 89  NYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKE 148

Query: 205 FVRCLLATPTKSEMR 219
             + L+AT  K  ++
Sbjct: 149 EQK-LIATSNKPAVK 162


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 36/98 (36%), Positives = 56/98 (57%), Gaps = 4/98 (4%)

Query: 88  TDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEP 147
           TD +TL+VGG  +TT+ +TL  + PD ML  MF   G +   +D +G + ID+    F  
Sbjct: 11  TDPVTLNVGGHLYTTSLTTL-TRYPDSMLGAMF--GGDFPTARDPQGNYFIDRDGPLFRY 67

Query: 148 ILNYLRHGQLIVNDGIDLLGVL-EEARFFGIDSLIEHL 184
           +LN+LR  +L +        +L +EA F+ I+ LI+ L
Sbjct: 68  VLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 36/98 (36%), Positives = 56/98 (57%), Gaps = 4/98 (4%)

Query: 88  TDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEP 147
           TD +TL+VGG  +TT+ +TL  + PD ML  MF   G +   +D +G + ID+    F  
Sbjct: 11  TDPVTLNVGGHLYTTSLTTL-TRYPDSMLGAMF--GGDFPTARDPQGNYFIDRDGPLFRY 67

Query: 148 ILNYLRHGQLIVNDGIDLLGVL-EEARFFGIDSLIEHL 184
           +LN+LR  +L +        +L +EA F+ I+ LI+ L
Sbjct: 68  VLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 5/107 (4%)

Query: 87  HTDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFE 146
           ++ ++ L+VGG    TT  TL  +  D ML  MF   G      D  G  LID+S  +F 
Sbjct: 39  NSKYVKLNVGGSLHYTTLRTLTGQ--DTMLKAMFS--GRVEVLTDAGGWVLIDRSGRHFG 94

Query: 147 PILNYLRHGQLIVNDGIDLLG-VLEEARFFGIDSLIEHLKVAIKNSQ 192
            ILNYLR G + + +    LG +L EAR++ +  LIE  ++A++  +
Sbjct: 95  TILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKR 141


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 33/94 (35%), Positives = 51/94 (54%), Gaps = 4/94 (4%)

Query: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPILNYL 152
           L+VGG+ F+T+  TL    PD   + +    G     +D  GA  ID+ P  F PILN+L
Sbjct: 23  LNVGGKRFSTSRQTLT-WIPDSFFSSLLS--GRISTLKDETGAIFIDRDPTVFAPILNFL 79

Query: 153 RHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKV 186
           R  +L    G+    +L EA+F+G+  L+  L++
Sbjct: 80  RTKELDPR-GVHGSSLLHEAQFYGLTPLVRRLQL 112


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPILNYL 152
           L+VGG  F+T+  TL+   PD   + +    G     +D  GA  ID+ P  F PILN+L
Sbjct: 22  LNVGGTRFSTSRQTLM-WIPDSFFSSLLS--GRISTLRDETGAIFIDRDPAAFAPILNFL 78

Query: 153 RHGQLIVNDGIDLLGVLEEARFFGIDSLIEHL 184
           R  +L +  G+ +  +  EA F+GI  L+  L
Sbjct: 79  RTKELDLR-GVSINVLRHEAEFYGITPLVRRL 109


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 2/97 (2%)

Query: 89  DWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPI 148
           D + L+VGGQ + T   T+V+  PD +L  MF  +      +D +G F +D+    F  I
Sbjct: 34  DIVELNVGGQVYVTRRCTVVSV-PDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYI 92

Query: 149 LNYLRHGQLIVNDGIDLLGVLE-EARFFGIDSLIEHL 184
           L+YLR  QL++ D       L+ EA +F +  L+  L
Sbjct: 93  LDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 4/95 (4%)

Query: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNK--QDHRGAFLIDQSPEYFEPILN 150
           L+VGGQ + T  STL++  P  +L  MF  K    N   +D +G F ID+    F  IL+
Sbjct: 29  LNVGGQVYFTRHSTLISI-PHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILD 87

Query: 151 YLRHGQLIVNDGIDLLGVLE-EARFFGIDSLIEHL 184
           YLR  Q+++ D     G L+ EA +F +  L++ L
Sbjct: 88  YLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 11/109 (10%)

Query: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQ-------DHRGAFLIDQSPEYF 145
           L+VGGQ + T  STL++  PD  LA MF      G  +       D R  F ID+    F
Sbjct: 48  LNVGGQVYVTKHSTLLSV-PDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLF 106

Query: 146 EPILNYLRHGQLIVNDGI-DLLGVLEEARFFGIDSLIEHL--KVAIKNS 191
             +L+YLR  QL + +   +   +L EA +F +  L++ L  KV  +NS
Sbjct: 107 RYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNS 155


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 33/96 (34%), Positives = 51/96 (53%), Gaps = 4/96 (4%)

Query: 91  LTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPILN 150
           +TL+VGG  + T   TL  K PD  L  +   K +     D  G + ID+    F  +LN
Sbjct: 35  MTLNVGGYLYITQKQTLT-KYPDTFLEGIVNGKILCPFDAD--GHYFIDRDGLLFRHVLN 91

Query: 151 YLRHGQLIVNDGIDLLGVL-EEARFFGIDSLIEHLK 185
           +LR+G+L++ +G     +L +EA FF +  L E +K
Sbjct: 92  FLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVK 127


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 39/100 (39%), Positives = 55/100 (55%), Gaps = 8/100 (8%)

Query: 89  DWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPI 148
           D L L+VGG  +T    +L   + D MLA MF   G +  K D  GA +ID+    F+ +
Sbjct: 12  DVLRLNVGGCIYTARRESLCRFK-DSMLASMFS--GRFPLKTDESGACVIDRDGRLFKYL 68

Query: 149 LNYLRHGQL-IVNDGIDLLGVLEEARFFGID---SLIEHL 184
           L+YL HG++ I  D    + + EEA +FGI    SL +HL
Sbjct: 69  LDYL-HGEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHL 107


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 49/160 (30%), Positives = 78/160 (48%), Gaps = 18/160 (11%)

Query: 67  GEPFIDPQTDSKPPEGLLGFH-----TDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFK 121
           G+  + P + +KP   L GF        ++ L+VGG  + TT   L     D ML  MF 
Sbjct: 3   GDTCLCPASGAKPK--LSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRH--DTMLKAMFS 58

Query: 122 DKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQL-IVNDGIDLLGVLEEARFFGIDSL 180
             G      D  G  LID+  ++F  ILNYLR   + +  +  ++  ++ EA+++ I  L
Sbjct: 59  --GRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGL 116

Query: 181 IEHLKVAI---KNSQPPEDHLPI--SRKEFVRCLLATPTK 215
           +   + A+   K+S  P  ++PI  S KE  R L+ + TK
Sbjct: 117 VNMCQSALQDKKDSYQPVCNIPIITSLKEEER-LIESSTK 155


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 10/107 (9%)

Query: 91  LTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHR---GAFLIDQSPEYFEP 147
           +TL+VGG+ FTT +ST + + P   LA M       G  Q+ +   G   +D+  + F  
Sbjct: 7   VTLNVGGKIFTTRFST-IKQFPASRLARMLD-----GRDQEFKMVGGQIFVDRDGDLFSF 60

Query: 148 ILNYLR-HGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQP 193
           IL++LR H  L+  +  D L +  EA F+ + SL++ L   +   +P
Sbjct: 61  ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRP 107


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 10/107 (9%)

Query: 91  LTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHR---GAFLIDQSPEYFEP 147
           +TL+VGG+ FTT +ST + + P   LA M       G  Q+ +   G   +D+  + F  
Sbjct: 7   VTLNVGGKIFTTRFST-IKQFPASRLARMLD-----GRDQEFKMVGGQIFVDRDGDLFSF 60

Query: 148 ILNYLR-HGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQP 193
           IL++LR H  L+  +  D L +  EA F+ + SL++ L   +   +P
Sbjct: 61  ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRP 107


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 17/148 (11%)

Query: 41  SVYNGNGGLNDDIVLIRDDDVLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYF 100
           S     GG    + L R        +G P     T S  P      H D     VGG  +
Sbjct: 18  STGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAP-----VHID-----VGGHMY 67

Query: 101 TTTWSTLVNKEPDIMLAHMFK--DKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLI 158
           T++ +TL  K PD  ++ +F   +  V  + + H   + ID+  E F  +L++LR  +L+
Sbjct: 68  TSSLATLT-KYPDSRISRLFNGTEPIVLDSLKQH---YFIDRDGEIFRYVLSFLRTSKLL 123

Query: 159 VNDGI-DLLGVLEEARFFGIDSLIEHLK 185
           + D   D   + EEAR++ +  ++  L+
Sbjct: 124 LPDDFKDFSLLYEEARYYQLQPMVRELE 151


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 17/148 (11%)

Query: 41  SVYNGNGGLNDDIVLIRDDDVLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYF 100
           S     GG    + L R        +G P     T S  P      H D     VGG  +
Sbjct: 18  STGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAP-----VHID-----VGGHMY 67

Query: 101 TTTWSTLVNKEPDIMLAHMFK--DKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLI 158
           T++ +TL  K PD  ++ +F   +  V  + + H   + ID+  E F  +L++LR  +L+
Sbjct: 68  TSSLATLT-KYPDSRISRLFNGTEPIVLDSLKQH---YFIDRDGEIFRYVLSFLRTSKLL 123

Query: 159 VNDGI-DLLGVLEEARFFGIDSLIEHLK 185
           + D   D   + EEAR++ +  ++  L+
Sbjct: 124 LPDDFKDFSLLYEEARYYQLQPMVRELE 151


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 17/148 (11%)

Query: 41  SVYNGNGGLNDDIVLIRDDDVLFVCEGEPFIDPQTDSKPPEGLLGFHTDWLTLHVGGQYF 100
           S     GG    + L R        +G P     T S  P      H D     VGG  +
Sbjct: 18  STGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAP-----VHID-----VGGHMY 67

Query: 101 TTTWSTLVNKEPDIMLAHMFK--DKGVWGNKQDHRGAFLIDQSPEYFEPILNYLRHGQLI 158
           T++ +TL  K PD  ++ +F   +  V  + + H   + ID+  E F  +L++LR  +L+
Sbjct: 68  TSSLATLT-KYPDSRISRLFNGTEPIVLDSLKQH---YFIDRDGEIFRYVLSFLRTSKLL 123

Query: 159 VNDGI-DLLGVLEEARFFGIDSLIEHLK 185
           + D   D   + EEAR++ +  ++  L+
Sbjct: 124 LPDDFKDFSLLYEEARYYQLQPMVRELE 151


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 26/92 (28%), Positives = 50/92 (54%), Gaps = 7/92 (7%)

Query: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFK--DKGVWGNKQDHRGAFLIDQSPEYFEPILN 150
           + VGG  +T++ +TL  K P+  +  +F   +  V  + + H   + ID+  + F  ILN
Sbjct: 642 IDVGGHMYTSSLATLT-KYPESRIGRLFDGTEPIVLDSLKQH---YFIDRDGQMFRYILN 697

Query: 151 YLRHGQLIVNDGI-DLLGVLEEARFFGIDSLI 181
           +LR  +L++ D   D   + EEA++F +  ++
Sbjct: 698 FLRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 729


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 26/92 (28%), Positives = 50/92 (54%), Gaps = 7/92 (7%)

Query: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFK--DKGVWGNKQDHRGAFLIDQSPEYFEPILN 150
           + VGG  +T++ +TL  K P+  +  +F   +  V  + + H   + ID+  + F  ILN
Sbjct: 34  IDVGGHMYTSSLATLT-KYPESRIGRLFDGTEPIVLDSLKQH---YFIDRDGQMFRYILN 89

Query: 151 YLRHGQLIVNDGI-DLLGVLEEARFFGIDSLI 181
           +LR  +L++ D   D   + EEA++F +  ++
Sbjct: 90  FLRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 26/92 (28%), Positives = 50/92 (54%), Gaps = 7/92 (7%)

Query: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFK--DKGVWGNKQDHRGAFLIDQSPEYFEPILN 150
           + VGG  +T++ +TL  K P+  +  +F   +  V  + + H   + ID+  + F  ILN
Sbjct: 34  IDVGGHMYTSSLATLT-KYPESRIGRLFDGTEPIVLDSLKQH---YFIDRDGQMFRYILN 89

Query: 151 YLRHGQLIVNDGI-DLLGVLEEARFFGIDSLI 181
           +LR  +L++ D   D   + EEA++F +  ++
Sbjct: 90  FLRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.140    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,708,581
Number of Sequences: 37866
Number of extensions: 483734
Number of successful extensions: 881
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 837
Number of HSP's gapped (non-prelim): 58
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.