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Search of human proteins with 110825961
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110825961 poly (ADP-ribose) polymerase family, member 2
isoform 1 [Homo sapiens]
(583 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110825961 poly (ADP-ribose) polymerase family, member 2 isofo... 1186 0.0
gi|110825963 poly (ADP-ribose) polymerase family, member 2 isofo... 1150 0.0
gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo... 386 e-107
gi|158634482 poly (ADP-ribose) polymerase family, member 3 isofo... 265 9e-71
gi|158634478 poly (ADP-ribose) polymerase family, member 3 isofo... 265 9e-71
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo... 103 3e-22
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 43 0.001
gi|24432009 poly (ADP-ribose) polymerase family, member 8 [Homo ... 41 0.003
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 40 0.008
gi|94536838 poly (ADP-ribose) polymerase family, member 6 [Homo ... 39 0.013
gi|154354979 myosin X [Homo sapiens] 38 0.023
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 35 0.15
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] 35 0.15
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 35 0.15
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 35 0.25
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 34 0.42
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 34 0.42
gi|30794488 kinesin family member 27 [Homo sapiens] 34 0.42
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 33 0.55
gi|221219020 NYD-SP11 protein [Homo sapiens] 33 0.72
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa... 33 0.72
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa... 33 0.72
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 33 0.95
gi|122937211 KIAA0368 protein [Homo sapiens] 32 1.2
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 32 1.6
gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Hom... 32 1.6
gi|4505531 oxysterol binding protein [Homo sapiens] 32 1.6
gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo sap... 32 2.1
gi|42476024 THUMP domain containing 1 [Homo sapiens] 32 2.1
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 31 2.8
>gi|110825961 poly (ADP-ribose) polymerase family, member 2 isoform
1 [Homo sapiens]
Length = 583
Score = 1186 bits (3068), Expect = 0.0
Identities = 583/583 (100%), Positives = 583/583 (100%)
Query: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60
MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD
Sbjct: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60
Query: 61 RTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN 120
RTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN
Sbjct: 61 RTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN 120
Query: 121 QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF 180
QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF
Sbjct: 121 QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF 180
Query: 181 LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE 240
LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE
Sbjct: 181 LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE 240
Query: 241 LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME 300
LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME
Sbjct: 241 LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME 300
Query: 301 ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ 360
ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ
Sbjct: 301 ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ 360
Query: 361 HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL 420
HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL
Sbjct: 361 HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL 420
Query: 421 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK 480
HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK
Sbjct: 421 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK 480
Query: 481 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP 540
NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP
Sbjct: 481 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP 540
Query: 541 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 583
ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW
Sbjct: 541 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 583
>gi|110825963 poly (ADP-ribose) polymerase family, member 2 isoform
2 [Homo sapiens]
Length = 570
Score = 1150 bits (2974), Expect = 0.0
Identities = 570/583 (97%), Positives = 570/583 (97%), Gaps = 13/583 (2%)
Query: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60
MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD
Sbjct: 1 MAARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKD 60
Query: 61 RTEDKQDGMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN 120
RTEDKQD ESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN
Sbjct: 61 RTEDKQD-------------ESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLN 107
Query: 121 QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF 180
QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF
Sbjct: 108 QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF 167
Query: 181 LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE 240
LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE
Sbjct: 168 LDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQE 227
Query: 241 LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME 300
LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME
Sbjct: 228 LIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME 287
Query: 301 ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ 360
ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ
Sbjct: 288 ACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQ 347
Query: 361 HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL 420
HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL
Sbjct: 348 HYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFREDL 407
Query: 421 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK 480
HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK
Sbjct: 408 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK 467
Query: 481 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP 540
NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP
Sbjct: 468 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP 527
Query: 541 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 583
ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW
Sbjct: 528 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQFNFLQLW 570
>gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo
sapiens]
Length = 1014
Score = 386 bits (991), Expect = e-107
Identities = 215/508 (42%), Positives = 317/508 (62%), Gaps = 16/508 (3%)
Query: 80 SESVKALLLKGKAPVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQLLED 139
SE L LKG A VDP+ + AHV +G V+ L ++ N YY +QLLED
Sbjct: 519 SEKRMKLTLKGGAAVDPDSGLE-HSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLED 577
Query: 140 DAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPG 199
D + + ++ WGRVG + + + + A E F K + +KT N W + F K P
Sbjct: 578 DKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKN-FTKYPK 636
Query: 200 KYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMK 259
K+ L++DY QDEE KK L +S+L VQ+LIK+I +V++M++ M+E +
Sbjct: 637 KFYPLEIDYG---QDEEAVKK---LTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYE 690
Query: 260 YNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPP 319
+ +K PLGKL+ QI+A Y L +++ + G +++ N FYT IPHDFG++ PP
Sbjct: 691 IDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPP 750
Query: 320 LIRTQKELSEKIQLLEALGDIEIAIKLVKTELQ-SPEHPLDQHYRNLHCALRPLDHESYE 378
L+ + K+++L+ L DIE+A L++ S + P+D +Y L ++ +D +S E
Sbjct: 751 LLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEE 810
Query: 379 FKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFR--EDLHNRMLLWHGSRMSNWV 436
++I +Y+++THA TH+ Y + ++D+F++E++GE + ++ + LHNR LLWHGSR +N+
Sbjct: 811 AEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFA 870
Query: 437 GILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCN 496
GILS GLRIAPPEAP+TGYMFGKGIYFADM SKSANYC S+ GL+LL EVALG
Sbjct: 871 GILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMY 930
Query: 497 ELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGPASDTGILNPDGYTLNY 556
EL A+ ++ L +GKHS KGLGK P + ++L+G VPLG +G+ + +L Y
Sbjct: 931 ELKHASHISK-LPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGV---NDTSLLY 986
Query: 557 NEYIVYNPNQVRMRYLLKVQFNF-LQLW 583
NEYIVY+ QV ++YLLK++FNF LW
Sbjct: 987 NEYIVYDIAQVNLKYLLKLKFNFKTSLW 1014
>gi|158634482 poly (ADP-ribose) polymerase family, member 3 isoform
b [Homo sapiens]
Length = 533
Score = 265 bits (677), Expect = 9e-71
Identities = 180/518 (34%), Positives = 283/518 (54%), Gaps = 35/518 (6%)
Query: 77 KRVSESVKALLLKGKA-PVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQ 135
+ +E++KA+ + + VDP C E Y+ LNQTN++ NNNK+Y+IQ
Sbjct: 30 RSTAEALKAIPAEKRIIRVDPTCPLSSNPGTQVYED---YNCTLNQTNIENNNNKFYIIQ 86
Query: 136 LLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFE 195
LL+D + R F+ W WGRVG++GQ S + L AK+ F+KKF +KTKNNW +R+ F
Sbjct: 87 LLQD-SNRFFTCWNHWGRVGEVGQ-SKINHFTRLEDAKKDFEKKFREKTKNNWAERDHFV 144
Query: 196 KVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQ------LDLRVQELIKLICNVQ 249
PGKY ++++ +DE + + + P++ ++ LD Q+LI I + +
Sbjct: 145 SHPGKYTLIEV----QAEDEAQEAVVKVDRGPVRTVTKRVQPCSLDPATQKLITNIFSKE 200
Query: 250 AMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRA-GQHGRALMEACNEFYTR 308
+ M M + KK PLGKL+ QI G+++L+ +E+ ++ G++L E + FYT
Sbjct: 201 MFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTV 260
Query: 309 IPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEI--AIKLVKTELQSPE---HPLDQHYR 363
IPH+FG PP I + + L K +L L DIE+ A++ V + ++ E HPLD+ Y+
Sbjct: 261 IPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEVPHPLDRDYQ 320
Query: 364 NLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFR--EDLH 421
L C L+ LD + E+KVI YL+ T + + TL +++V ++GE++ F+ L
Sbjct: 321 LLKCQLQLLDSGAPEYKVIQTYLEQTGS---NHRCPTLQHIWKVNQEGEEDRFQAHSKLG 377
Query: 422 NRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASR--L 479
NR LLWHG+ M+ IL+ GLRI P +G GKGIYFA +SKSA Y +
Sbjct: 378 NRKLLWHGTNMAVVAAILTSGLRIMPH----SGGRVGKGIYFASENSKSAGYVIGMKCGA 433
Query: 480 KNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHS--TKGLGKMAPSSAHFVTLNGSTVP 537
+ G + L EVALG+ + + NP + G S +G + P+ + L+G V
Sbjct: 434 HHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDGQQVV 493
Query: 538 LGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKV 575
+ T + +EY++Y +Q R+RYLL+V
Sbjct: 494 VPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEV 531
>gi|158634478 poly (ADP-ribose) polymerase family, member 3 isoform
a [Homo sapiens]
Length = 540
Score = 265 bits (677), Expect = 9e-71
Identities = 180/518 (34%), Positives = 283/518 (54%), Gaps = 35/518 (6%)
Query: 77 KRVSESVKALLLKGKA-PVDPECTAKVGKAHVYCEGNDVYDVMLNQTNLQFNNNKYYLIQ 135
+ +E++KA+ + + VDP C E Y+ LNQTN++ NNNK+Y+IQ
Sbjct: 37 RSTAEALKAIPAEKRIIRVDPTCPLSSNPGTQVYED---YNCTLNQTNIENNNNKFYIIQ 93
Query: 136 LLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFE 195
LL+D + R F+ W WGRVG++GQ S + L AK+ F+KKF +KTKNNW +R+ F
Sbjct: 94 LLQD-SNRFFTCWNHWGRVGEVGQ-SKINHFTRLEDAKKDFEKKFREKTKNNWAERDHFV 151
Query: 196 KVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQ------LDLRVQELIKLICNVQ 249
PGKY ++++ +DE + + + P++ ++ LD Q+LI I + +
Sbjct: 152 SHPGKYTLIEV----QAEDEAQEAVVKVDRGPVRTVTKRVQPCSLDPATQKLITNIFSKE 207
Query: 250 AMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRA-GQHGRALMEACNEFYTR 308
+ M M + KK PLGKL+ QI G+++L+ +E+ ++ G++L E + FYT
Sbjct: 208 MFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTV 267
Query: 309 IPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEI--AIKLVKTELQSPE---HPLDQHYR 363
IPH+FG PP I + + L K +L L DIE+ A++ V + ++ E HPLD+ Y+
Sbjct: 268 IPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEVPHPLDRDYQ 327
Query: 364 NLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFR--EDLH 421
L C L+ LD + E+KVI YL+ T + + TL +++V ++GE++ F+ L
Sbjct: 328 LLKCQLQLLDSGAPEYKVIQTYLEQTGS---NHRCPTLQHIWKVNQEGEEDRFQAHSKLG 384
Query: 422 NRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASR--L 479
NR LLWHG+ M+ IL+ GLRI P +G GKGIYFA +SKSA Y +
Sbjct: 385 NRKLLWHGTNMAVVAAILTSGLRIMPH----SGGRVGKGIYFASENSKSAGYVIGMKCGA 440
Query: 480 KNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHS--TKGLGKMAPSSAHFVTLNGSTVP 537
+ G + L EVALG+ + + NP + G S +G + P+ + L+G V
Sbjct: 441 HHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDGQQVV 500
Query: 538 LGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKV 575
+ T + +EY++Y +Q R+RYLL+V
Sbjct: 501 VPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEV 538
>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
sapiens]
Length = 1724
Score = 103 bits (258), Expect = 3e-22
Identities = 90/351 (25%), Positives = 148/351 (42%), Gaps = 52/351 (14%)
Query: 232 SQLDLRVQELIKLICN--VQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCI 289
S L V +L+++I + +E M+++ P+ ++++ + L ++ +
Sbjct: 257 STLSQEVSDLVEMIWAEALGHLEHMLLK--------PVNRISLNDVSKAEGILLLVKAAL 308
Query: 290 RAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKT 349
+ G+ L + EFY IPH T P L++K L + + D+ + + +T
Sbjct: 309 KNGETAEQLQKMMTEFYRLIPHK---GTMPKEVNLGLLAKKADLCQLIRDM---VNVCET 362
Query: 350 ELQSPEHPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEK 409
L P P YR L C + ++ + EF + + + H HS + +L +F V +
Sbjct: 363 NLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNH---HSKSPVDVLQIFRVGR 419
Query: 410 DGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYM------FGKGIYF 463
E F L N L HGS + N VGIL GL + P G G GIYF
Sbjct: 420 VNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGL-LLPKVVEDRGVQRTDVGNLGSGIYF 478
Query: 464 ADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAP 523
+D S S Y T LLL+ +VALG+C +L E + G S G+ + A
Sbjct: 479 SDSLSTSIKYSHPGETDGTRLLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTAS 538
Query: 524 SSAHFVTLNGSTVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLK 574
+ F +E++VY NQV+M+Y++K
Sbjct: 539 VTTDF--------------------------EDDEFVVYKTNQVKMKYIIK 563
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 42.7 bits (99), Expect = 0.001
Identities = 47/156 (30%), Positives = 60/156 (38%), Gaps = 23/156 (14%)
Query: 421 HNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLK 480
HN +L+HGS N I+ G G MFG GIYFA+ SSKS Y +
Sbjct: 1177 HNERMLFHGSPFIN--AIIHKGF---DERHAYIGGMFGAGIYFAENSSKSNQYVYGIG-G 1230
Query: 481 NTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGSTVPLGP 540
TG + + C+ Q LGK S F T+ + P G
Sbjct: 1231 GTGCPTHKDRSCYICHR------------QMLFCRVTLGK---SFLQFSTMKMAHAPPGH 1275
Query: 541 ASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQ 576
S G P L Y EY++Y Q YL+ Q
Sbjct: 1276 HSVIG--RPSVNGLAYAEYVIYRGEQAYPEYLITYQ 1309
>gi|24432009 poly (ADP-ribose) polymerase family, member 8 [Homo
sapiens]
Length = 854
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 427 WHGSRMSNWVGILSHGLRIAP-PEAPITGYMFGKGIYFADMSSKSANY 473
+HGS + NW IL +GL +A + G M+G GIY + MSS S Y
Sbjct: 696 FHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSSISFGY 743
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 39.7 bits (91), Expect = 0.008
Identities = 55/222 (24%), Positives = 84/222 (37%), Gaps = 40/222 (18%)
Query: 372 LDHESYEFKVISQYLQST----HAPTHSDYTMTLLDLFEVEKDGEKEAFREDLH------ 421
L + EF+ + + +QST H+ ++ +++K K+ + H
Sbjct: 958 LSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVS 1017
Query: 422 -------NRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANYC 474
N +L+HGS N I+ G G MFG GIYFA+ SSKS Y
Sbjct: 1018 EENHNHANERMLFHGSPFVN--AIIHKGF---DERHAYIGGMFGAGIYFAENSSKSNQYV 1072
Query: 475 FASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHFVTLNGS 534
+ TG + + + C+ L LGK S F + +
Sbjct: 1073 YGIG-GGTGCPVHKDRSCYICHRQL------------LFCRVTLGK---SFLQFSAMKMA 1116
Query: 535 TVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRYLLKVQ 576
P G S TG + +G L EY++Y Q YL+ Q
Sbjct: 1117 HSPPGHHSVTGRPSVNGLAL--AEYVIYRGEQAYPEYLITYQ 1156
>gi|94536838 poly (ADP-ribose) polymerase family, member 6 [Homo
sapiens]
Length = 630
Score = 38.9 bits (89), Expect = 0.013
Identities = 40/158 (25%), Positives = 60/158 (37%), Gaps = 25/158 (15%)
Query: 322 RTQKELSEKIQLLEALGDIEIAIKLVKTELQSPEHPLDQHY---RNLHCALRPLDHESYE 378
R QK L + + E + IK +L HPL Q H PL +
Sbjct: 381 RLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQWIISSNRSHIVKLPLSRLKF- 439
Query: 379 FKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFR--EDLHNRMLLWHGSRMSNWV 436
H+ + LL ++ FR + L+ +HGS + NW
Sbjct: 440 --------------MHTSHQFLLLS----SPPAKEARFRTAKKLYGSTFAFHGSHIENWH 481
Query: 437 GILSHGL-RIAPPEAPITGYMFGKGIYFADMSSKSANY 473
IL +GL + + + G +GKGIY + +SS S Y
Sbjct: 482 SILRNGLVNASYTKLQLHGAAYGKGIYLSPISSISFGY 519
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 38.1 bits (87), Expect = 0.023
Identities = 27/123 (21%), Positives = 61/123 (49%), Gaps = 14/123 (11%)
Query: 182 DKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDL----- 236
+K K E+++K E+ + + + + Q EEET+K++ L++ K + + +L
Sbjct: 820 EKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELE 879
Query: 237 ------RVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIR 290
+V+E+++L ++ ++ M + + + +A L KL Q + + + E+ R
Sbjct: 880 KQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKL---QERRDQELRRLEEEACR 936
Query: 291 AGQ 293
A Q
Sbjct: 937 AAQ 939
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 35.4 bits (80), Expect = 0.15
Identities = 32/138 (23%), Positives = 59/138 (42%), Gaps = 23/138 (16%)
Query: 189 EDREKFEKVPGKYDMLQMDYATNTQDEEETKKEE---------SLKSPLKPESQLDLRVQ 239
EDRE+F K + ++L D ++ ++E LK+ + Q D ++
Sbjct: 1449 EDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIE 1508
Query: 240 ELIKLICNVQAMEEMMMEMK-YNTKKAPLGKLTVAQIKAGYQ-SLKKIEDCIRAGQHGRA 297
+L ++I +E +M++K A KL + ++ S KIED G
Sbjct: 1509 QLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIED-------GSV 1561
Query: 298 LMEAC-----NEFYTRIP 310
++++C N+ TR P
Sbjct: 1562 VLDSCEVSTENDQSTRFP 1579
>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
Length = 1226
Score = 35.4 bits (80), Expect = 0.15
Identities = 34/144 (23%), Positives = 70/144 (48%), Gaps = 21/144 (14%)
Query: 181 LDKTKNNWEDREKFEKVPGKYDM-------LQMDYATNTQDEEETKKEESLKSPL----- 228
L ++++ ED E+ E G DM ++D+ TN +++ +K+E++ S L
Sbjct: 621 LQASESSAEDSEQ-EDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKV 679
Query: 229 -------KPESQLDLRVQELIKLIC-NVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQ 280
KP S+ R+++ I+++ + E+ + + + + KK K + QIK G +
Sbjct: 680 HADLVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTKKRKDVKKDTTDKSSKPQIKRGKR 739
Query: 281 SLKKIEDCIRAGQHGRALMEACNE 304
E+C++ G G+ +A N+
Sbjct: 740 RYCNTEECLKTGSPGKKEEKAKNK 763
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 35.4 bits (80), Expect = 0.15
Identities = 34/144 (23%), Positives = 70/144 (48%), Gaps = 21/144 (14%)
Query: 181 LDKTKNNWEDREKFEKVPGKYDM-------LQMDYATNTQDEEETKKEESLKSPL----- 228
L ++++ ED E+ E G DM ++D+ TN +++ +K+E++ S L
Sbjct: 707 LQASESSAEDSEQ-EDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKV 765
Query: 229 -------KPESQLDLRVQELIKLIC-NVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQ 280
KP S+ R+++ I+++ + E+ + + + + KK K + QIK G +
Sbjct: 766 HADLVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTKKRKDVKKDTTDKSSKPQIKRGKR 825
Query: 281 SLKKIEDCIRAGQHGRALMEACNE 304
E+C++ G G+ +A N+
Sbjct: 826 RYCNTEECLKTGSPGKKEEKAKNK 849
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 34.7 bits (78), Expect = 0.25
Identities = 18/63 (28%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 5 RRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGGKANKDRTED 64
RRRS R R+ + S+ SSP K+++ + + K GG+++K++ +D
Sbjct: 82 RRRSRSRDRRRSRSRSR-----GRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKD 136
Query: 65 KQD 67
K D
Sbjct: 137 KDD 139
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 33.9 bits (76), Expect = 0.42
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 191 REKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQA 250
+E E P K + ++ DY+ + + E+ T KEE K P + LD + ++ +
Sbjct: 1063 KEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK------RKRK 1116
Query: 251 MEEMMMEMKYNTKKAPLGKLTVAQI 275
EE ++ + + + KL V +I
Sbjct: 1117 TEEKGVDKDFESSSMKISKLEVTEI 1141
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 33.9 bits (76), Expect = 0.42
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 191 REKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQA 250
+E E P K + ++ DY+ + + E+ T KEE K P + LD + ++ +
Sbjct: 1097 KEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEK------RKRK 1150
Query: 251 MEEMMMEMKYNTKKAPLGKLTVAQI 275
EE ++ + + + KL V +I
Sbjct: 1151 TEEKGVDKDFESSSMKISKLEVTEI 1175
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 33.9 bits (76), Expect = 0.42
Identities = 34/167 (20%), Positives = 73/167 (43%), Gaps = 23/167 (13%)
Query: 203 MLQMDYATNTQDEEETKKEES---------LKSP-----------LKPESQLDLRVQELI 242
+L ++ N+ DEE +E+S ++ P + E+Q E +
Sbjct: 637 VLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDL 696
Query: 243 KLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKK-IEDCIRAGQHGRALMEA 301
K+ C ++ E + ++K + + K + ++ + + I++ I+ G +++ +
Sbjct: 697 KIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQ 756
Query: 302 CNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVK 348
+ T++ HD LI TQK+L E + L D+ + +KL K
Sbjct: 757 YSLKVTKLEHDAEQAKVELIETQKQLQELEN--KDLSDVAMKVKLQK 801
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 33.5 bits (75), Expect = 0.55
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 9/83 (10%)
Query: 5 RRRSTGGGRARALNESK-------RVNNGNTAPEDSSPAKKTRRCQRQESKKMPVAGG-- 55
R RS GG R+R+ + SK R + + S K+ R +++ SK+ AG
Sbjct: 333 RSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK 392
Query: 56 KANKDRTEDKQDGMPGRSWASKR 78
K K+ T+ Q P RS + +R
Sbjct: 393 KKKKEDTDRSQSRSPSRSVSKER 415
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 33.1 bits (74), Expect = 0.72
Identities = 30/132 (22%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Query: 133 LIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKF--LDKTKNN--W 188
L Q E AQ+ + +W +V + + L G L + K I +K L + + N W
Sbjct: 1651 LSQEAEKLAQKRKKLAKKWEKVARE-EEKLAKKGGKLAEVKNILAQKVEELPQREQNLDW 1709
Query: 189 EDREKFEKVPG-KYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICN 247
+++E +++ ++DM ++ + ++EE K E K + E L + ++L +
Sbjct: 1710 QEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETK 1769
Query: 248 VQAMEEMMMEMK 259
+ EE++++ K
Sbjct: 1770 LAQEEELLIQEK 1781
Score = 29.6 bits (65), Expect = 8.0
Identities = 24/74 (32%), Positives = 34/74 (45%), Gaps = 7/74 (9%)
Query: 173 KEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESL-------K 225
KE +KK K K E +EK E K +++ + + DEEE ++ SL K
Sbjct: 2282 KEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341
Query: 226 SPLKPESQLDLRVQ 239
LK E Q L+ Q
Sbjct: 2342 EILKKEKQFKLQEQ 2355
>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
sapiens]
Length = 1690
Score = 33.1 bits (74), Expect = 0.72
Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 17/132 (12%)
Query: 230 PESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLG-----KLTVAQIKAGYQSLKK 284
PE+ L ++++ +K ++ ++++ K +++P KLTV ++KA Q L
Sbjct: 776 PENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFS 835
Query: 285 IEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGD---IE 341
+ I + + L++ EF+ R TP S K+Q+L +G +E
Sbjct: 836 LPCVISQARQVKNLLDDVEEFHERAQEAMMDETPD--------SSKLQMLIDMGSSLYVE 887
Query: 342 I-AIKLVKTELQ 352
+ + +K ELQ
Sbjct: 888 LPELPRLKQELQ 899
>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
sapiens]
Length = 1641
Score = 33.1 bits (74), Expect = 0.72
Identities = 31/132 (23%), Positives = 61/132 (46%), Gaps = 17/132 (12%)
Query: 230 PESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLG-----KLTVAQIKAGYQSLKK 284
PE+ L ++++ +K ++ ++++ K +++P KLTV ++KA Q L
Sbjct: 776 PENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFS 835
Query: 285 IEDCIRAGQHGRALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGD---IE 341
+ I + + L++ EF+ R TP S K+Q+L +G +E
Sbjct: 836 LPCVISQARQVKNLLDDVEEFHERAQEAMMDETPD--------SSKLQMLIDMGSSLYVE 887
Query: 342 I-AIKLVKTELQ 352
+ + +K ELQ
Sbjct: 888 LPELPRLKQELQ 899
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 32.7 bits (73), Expect = 0.95
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 5/72 (6%)
Query: 2 AARRRRSTGGGRARALNESKRVNNGNTAPEDSSPAKKTRRCQRQE-----SKKMPVAGGK 56
+A +S GGG + L E+KR +G P +P ++ ++ + SKK G K
Sbjct: 374 SAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPK 433
Query: 57 ANKDRTEDKQDG 68
A K R + G
Sbjct: 434 AAKSRGGKSRSG 445
>gi|122937211 KIAA0368 protein [Homo sapiens]
Length = 2017
Score = 32.3 bits (72), Expect = 1.2
Identities = 71/306 (23%), Positives = 117/306 (38%), Gaps = 99/306 (32%)
Query: 68 GMPGRSWASKRVSESVKALLLKGKAPVDPECTAKVGKAHVYCEG-NDVYDVMLNQTNLQF 126
G+ GR+WA K LLK A V C+A++ K+ N++ +L + + +
Sbjct: 1748 GLAGRTWAGKEE-------LLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKE- 1799
Query: 127 NNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKN 186
N KY ++ ++C+ ++ KA +
Sbjct: 1800 -NVKYKIVA---------------------------ISCAADILKATK------------ 1819
Query: 187 NWEDR-EKFEKVPG---KYDMLQMDYATNTQDEEETKKEESLKS--------------PL 228
EDR ++F + K + L+ T++EEE +KE+ L+ P
Sbjct: 1820 --EDRFQEFSNIVIPLIKKNSLESSGVRTTKNEEENEKEKELQLEYLLGAFESLGKAWPR 1877
Query: 229 KPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDC 288
E+Q R QEL KL+C +K +T K LG L + A +Q L +E+
Sbjct: 1878 NAETQRCYR-QELCKLMCE---------RLKLSTWKVQLGVL--QSMNAFFQGLMLLEE- 1924
Query: 289 IRAGQHG--RALMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKL 346
+H AL E E I + +T +RT EAL IE+ +K
Sbjct: 1925 ----EHADPEALAEILLETCKSITYSLENKTYSSVRT-----------EALSVIELLLKK 1969
Query: 347 VKTELQ 352
++ Q
Sbjct: 1970 LEESKQ 1975
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 32.0 bits (71), Expect = 1.6
Identities = 29/126 (23%), Positives = 58/126 (46%), Gaps = 11/126 (8%)
Query: 182 DKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQEL 241
DK K N + RE + + LQ +YA+ ++ E +KE S K + Q+L
Sbjct: 1472 DKQKENDKLRESLSRKTVSLEHLQREYASVKEENERLQKEGSEK---------ERHNQQL 1522
Query: 242 IKLI-CNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHG-RALM 299
I+ + C+ Q + + E+K + + ++ ++ +K+++ R + G + M
Sbjct: 1523 IQEVRCSGQELSRVQEEVKLRQQLLSQNDKLLQSLRVELKAYEKLDEEHRRLRDGDKYPM 1582
Query: 300 EACNEF 305
E+ N F
Sbjct: 1583 ESDNSF 1588
>gi|194328777 poly (ADP-ribose) polymerase family, member 11 [Homo
sapiens]
Length = 338
Score = 32.0 bits (71), Expect = 1.6
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 15/129 (11%)
Query: 357 PLDQHYRNLHCA----LRPLDHESYEFKVISQYLQSTHAPTHSDYTMTL--LDLFEV--- 407
P+ H+ N++ L PL ++++E+ ++ T + LDL+E
Sbjct: 124 PMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEFFCR 183
Query: 408 EKDGEKEAFREDLHNRMLLWHGSRMSNWVGILSHGL--RIAPPEAPITGYMFGKGIYFAD 465
+K K+ N +L+HG+ I H RI I G +FGKG YFA
Sbjct: 184 KKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRING----IHGAVFGKGTYFAR 239
Query: 466 MSSKSANYC 474
++ S+ +C
Sbjct: 240 DAAYSSRFC 248
>gi|4505531 oxysterol binding protein [Homo sapiens]
Length = 807
Score = 32.0 bits (71), Expect = 1.6
Identities = 30/122 (24%), Positives = 51/122 (41%), Gaps = 9/122 (7%)
Query: 155 GKMGQHSLVACSGNLNKAKEIFQKKFLDKTK-----NNWEDREKFEKVPGKYDMLQMDYA 209
G +G CSG + + E + +F D + N + + G + +D
Sbjct: 334 GNVGSGKDQCCSGKGDMSDEDDENEFFDAPEIITMPENLGHKRTGSNISGASSDISLDEQ 393
Query: 210 TNTQDEEETKKEESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGK 269
Q EETKKE+ + P KP L+L I C + + ++ M + +N + L +
Sbjct: 394 YKHQ-LEETKKEKRTRIPYKPNYSLNL---WSIMKNCIGKELSKIPMPVNFNEPLSMLQR 449
Query: 270 LT 271
LT
Sbjct: 450 LT 451
>gi|38524594 TCDD-inducible poly(ADP-ribose) polymerase [Homo
sapiens]
Length = 657
Score = 31.6 bits (70), Expect = 2.1
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 417 REDLHNRMLLWHGSRMSNWVGILSHGL--RIAPPEAPITGYMFGKGIYFADMSSKSANYC 474
R+ + N L+HG+ GI H R+ A MFG+G YFA +S S N+
Sbjct: 521 RDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHAT----MFGQGSYFAKKASYSHNFS 576
Query: 475 FASRLKNTGLLLLSEVALGQ 494
S K + L++V G+
Sbjct: 577 KKSS-KGVHFMFLAKVLTGR 595
>gi|42476024 THUMP domain containing 1 [Homo sapiens]
Length = 353
Score = 31.6 bits (70), Expect = 2.1
Identities = 33/133 (24%), Positives = 58/133 (43%), Gaps = 14/133 (10%)
Query: 178 KKFLDKTKNNWED-REKFEKVPGKYDMLQMDYATNTQD----EEETKKEESLKSPLKPES 232
K FL+ K E E + K P K Q+ Y + EE ++ + L E+
Sbjct: 170 KAFLEDMKKYAETFLEPWFKAPNK-GTFQIVYKSRNNSHVNREEVIRELAGIVCTLNSEN 228
Query: 233 QLDLR------VQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQI--KAGYQSLKK 284
++DL V E+IK +C + +++ M+ KYN ++ +Q+ K G K
Sbjct: 229 KVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAK 288
Query: 285 IEDCIRAGQHGRA 297
+E ++ Q+ A
Sbjct: 289 LESADKSDQNNTA 301
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 31.2 bits (69), Expect = 2.8
Identities = 29/124 (23%), Positives = 56/124 (45%), Gaps = 16/124 (12%)
Query: 182 DKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKKEESLKSPLKPESQLDLRVQEL 241
DK K N + RE + + LQ +YA+ ++ E +KE S K + Q+L
Sbjct: 1472 DKQKENDKLRESLSRKTVSLEHLQREYASVKEENERLQKEGSEK---------ERHNQQL 1522
Query: 242 IKLI-CNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALME 300
I+ + C+ Q + + E+K + + ++ ++ +K+++ +H R L E
Sbjct: 1523 IQEVRCSGQELSRVQEEVKLRQQLLSQNDKLLQSLRVELKAYEKLDE-----EH-RRLRE 1576
Query: 301 ACNE 304
A E
Sbjct: 1577 ASGE 1580
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,557,237
Number of Sequences: 37866
Number of extensions: 1031746
Number of successful extensions: 3873
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 3802
Number of HSP's gapped (non-prelim): 82
length of query: 583
length of database: 18,247,518
effective HSP length: 108
effective length of query: 475
effective length of database: 14,157,990
effective search space: 6725045250
effective search space used: 6725045250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.