Guide to the Human Genome
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Search of human proteins with 169172508

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169172508 PREDICTED: hypothetical protein [Homo sapiens]
         (402 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169172508 PREDICTED: hypothetical protein [Homo sapiens]           828   0.0  
gi|169173078 PREDICTED: hypothetical protein [Homo sapiens]           825   0.0  
gi|169173306 PREDICTED: hypothetical protein [Homo sapiens]           383   e-106
gi|239749426 PREDICTED: hypothetical protein XP_002347042 [Homo ...   153   2e-37
gi|239743560 PREDICTED: hypothetical protein XP_002342893 [Homo ...   153   2e-37
gi|239754887 PREDICTED: hypothetical protein XP_002346152 [Homo ...   153   3e-37
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   8e-06
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap...    49   1e-05
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap...    49   1e-05
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               49   1e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      48   1e-05
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    48   2e-05
gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]            48   2e-05
gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]            48   2e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    47   2e-05
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 47   3e-05
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    46   7e-05
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     45   9e-05
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       45   9e-05
gi|239756845 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|169211031 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    45   1e-04
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    45   1e-04
gi|13129104 coiled-coil domain containing 86 [Homo sapiens]            45   1e-04
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      45   2e-04
gi|239747641 PREDICTED: hypothetical protein XP_002347916 [Homo ...    45   2e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   2e-04
gi|169211844 PREDICTED: hypothetical protein [Homo sapiens]            44   2e-04
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             44   2e-04
gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I...    44   3e-04

>gi|169172508 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 402

 Score =  828 bits (2138), Expect = 0.0
 Identities = 402/402 (100%), Positives = 402/402 (100%)

Query: 1   MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQR 60
           MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQR
Sbjct: 1   MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQR 60

Query: 61  PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS 120
           PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS
Sbjct: 61  PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS 120

Query: 121 CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS 180
           CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS
Sbjct: 121 CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS 180

Query: 181 SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR 240
           SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR
Sbjct: 181 SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR 240

Query: 241 HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP 300
           HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP
Sbjct: 241 HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP 300

Query: 301 NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS 360
           NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS
Sbjct: 301 NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS 360

Query: 361 IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402
           IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR
Sbjct: 361 IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402


>gi|169173078 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 402

 Score =  825 bits (2132), Expect = 0.0
 Identities = 401/402 (99%), Positives = 401/402 (99%)

Query: 1   MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQR 60
           MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGG GAGVRPEPCAGQR
Sbjct: 1   MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQR 60

Query: 61  PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS 120
           PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS
Sbjct: 61  PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS 120

Query: 121 CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS 180
           CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS
Sbjct: 121 CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS 180

Query: 181 SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR 240
           SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR
Sbjct: 181 SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR 240

Query: 241 HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP 300
           HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP
Sbjct: 241 HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP 300

Query: 301 NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS 360
           NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS
Sbjct: 301 NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS 360

Query: 361 IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402
           IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR
Sbjct: 361 IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402


>gi|169173306 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 281

 Score =  383 bits (983), Expect = e-106
 Identities = 189/190 (99%), Positives = 189/190 (99%)

Query: 213 PGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAP 272
           P RRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAP
Sbjct: 92  PRRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAP 151

Query: 273 KPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGA 332
           KPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGA
Sbjct: 152 KPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGA 211

Query: 333 SSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLP 392
           SSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLP
Sbjct: 212 SSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLP 271

Query: 393 SEESLSQRSR 402
           SEESLSQRSR
Sbjct: 272 SEESLSQRSR 281



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 31/111 (27%), Positives = 42/111 (37%), Gaps = 6/111 (5%)

Query: 265 APGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATL 324
           +P LPR   P+ G        R  ++  +L G P P    R  P   H   +       L
Sbjct: 32  SPALPRPGFPAPGFPALRLPRRRAQLGVKLGGGPSPASGARPSP---HLEGAGCETRPWL 88

Query: 325 RAPPGRGASSETMWP--TENLSSRRRAPPQR-RRTRAPSIARSLPGSGRLQ 372
              P R  +     P     L  R  A P R RR RAP +A  + G  R++
Sbjct: 89  GPRPRRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIR 139


>gi|239749426 PREDICTED: hypothetical protein XP_002347042 [Homo
           sapiens]
          Length = 517

 Score =  153 bits (387), Expect = 2e-37
 Identities = 139/348 (39%), Positives = 163/348 (46%), Gaps = 90/348 (25%)

Query: 9   RDLRLAAGAGQAW-------------------GSAGRGRRGPAPRGQTGTQGVGSGGGGA 49
           RDLR+A GAG+                     G  GRG+R    R +  T  V      A
Sbjct: 196 RDLRVAVGAGRRAVPGHRGGEESRVGVHAVQRGRVGRGQRVAVERRRAQTLAVAVVA--A 253

Query: 50  GVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANGW--GTVLVSGLVPQDPRAAPPPGGR 107
            VR +    QR AGG+AL GE +AQA  G+AAA G   G + +S  V +       P   
Sbjct: 254 HVRRQ----QRRAGGEALLGELEAQAVHGHAAALGAQRGRLRLSQAVQEAALHPLQP--- 306

Query: 108 QLLLLRPPRWV-------------PSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQ 154
            L LL PPR V             P C  + +   + Q  R P                 
Sbjct: 307 -LHLLAPPRPVLVVGVVLHVLHAQPLCLLH-EGPLLRQRQRLP----------------- 347

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRP----TWKAPDARLALGSA 210
                   R      A  GV + W      + RQPLAL L P      + PD  LALGSA
Sbjct: 348 --------RLACTHLAQLGVVQVWI-----LLRQPLALVLSPHHESVHRPPDTGLALGSA 394

Query: 211 RGPGR------RLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHG 264
           RGPGR      RLALHL VP+GA++LGP  GAQP  HR QRA GLALVVTGVSRIR AHG
Sbjct: 395 RGPGRCSAVRRRLALHLHVPDGAQRLGPGAGAQPGHHRGQRALGLALVVTGVSRIRAAHG 454

Query: 265 APGLPRAPKPSAGRGGK--EGGERGTEMLR---RLRGSPRPNRHPRSG 307
           APGLPR+P+PSAGR      G   G+E LR      G P  +R P SG
Sbjct: 455 APGLPRSPQPSAGRAASPDPGEGVGSEALRCPEGCAGLPARSRRPCSG 502


>gi|239743560 PREDICTED: hypothetical protein XP_002342893 [Homo
           sapiens]
          Length = 517

 Score =  153 bits (387), Expect = 2e-37
 Identities = 139/348 (39%), Positives = 163/348 (46%), Gaps = 90/348 (25%)

Query: 9   RDLRLAAGAGQAW-------------------GSAGRGRRGPAPRGQTGTQGVGSGGGGA 49
           RDLR+A GAG+                     G  GRG+R    R +  T  V      A
Sbjct: 196 RDLRVAVGAGRRAVPGHRGGEESRVGVHAVQRGRVGRGQRVAVERRRAQTLAVAVVA--A 253

Query: 50  GVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANGW--GTVLVSGLVPQDPRAAPPPGGR 107
            VR +    QR AGG+AL GE +AQA  G+AAA G   G + +S  V +       P   
Sbjct: 254 HVRRQ----QRRAGGEALLGELEAQAVHGHAAALGAQRGRLRLSQAVQEAALHPLQP--- 306

Query: 108 QLLLLRPPRWV-------------PSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQ 154
            L LL PPR V             P C  + +   + Q  R P                 
Sbjct: 307 -LHLLAPPRPVLVVGVVLHVLHAQPLCLLH-EGPLLRQRQRLP----------------- 347

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRP----TWKAPDARLALGSA 210
                   R      A  GV + W      + RQPLAL L P      + PD  LALGSA
Sbjct: 348 --------RLACTHLAQLGVVQVWI-----LLRQPLALVLSPHHESVHRPPDTGLALGSA 394

Query: 211 RGPGR------RLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHG 264
           RGPGR      RLALHL VP+GA++LGP  GAQP  HR QRA GLALVVTGVSRIR AHG
Sbjct: 395 RGPGRCSAVRRRLALHLHVPDGAQRLGPGAGAQPGHHRGQRALGLALVVTGVSRIRAAHG 454

Query: 265 APGLPRAPKPSAGRGGK--EGGERGTEMLR---RLRGSPRPNRHPRSG 307
           APGLPR+P+PSAGR      G   G+E LR      G P  +R P SG
Sbjct: 455 APGLPRSPQPSAGRAASPDPGEGVGSEALRCPEGCAGLPARSRRPCSG 502


>gi|239754887 PREDICTED: hypothetical protein XP_002346152 [Homo
           sapiens]
          Length = 517

 Score =  153 bits (386), Expect = 3e-37
 Identities = 139/348 (39%), Positives = 162/348 (46%), Gaps = 90/348 (25%)

Query: 9   RDLRLAAGAGQAW-------------------GSAGRGRRGPAPRGQTGTQGVGSGGGGA 49
           RDLR+A GAG+                     G  GRG+R    R +  T  V      A
Sbjct: 196 RDLRVAVGAGRRAVPGHRGGEESRVGVHAVQRGRVGRGQRVAVERRRAQTLAVAVVA--A 253

Query: 50  GVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANGW--GTVLVSGLVPQDPRAAPPPGGR 107
            VR +    QR AGG+AL GE +AQA  G+AAA G   G + +S  V +       P   
Sbjct: 254 HVRRQ----QRRAGGEALLGELEAQAVHGHAAALGAQRGRLRLSQAVQEAALHPLQP--- 306

Query: 108 QLLLLRPPRWV-------------PSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQ 154
            L LL PPR V             P C  + +   + Q  R P                 
Sbjct: 307 -LHLLAPPRPVLVVGVVLHVLHAQPLCLLH-EGPLLRQRQRLP----------------- 347

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRP----TWKAPDARLALGSA 210
                   R      A  GV + W      + RQPLAL L P      + PD  LALGSA
Sbjct: 348 --------RLACTHLAQLGVVQVWI-----LLRQPLALVLSPHHESVHRPPDTGLALGSA 394

Query: 211 RGPGR------RLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHG 264
           RGPGR      RLALHL VP+GA++LGP  GAQP  HR QRA GLALVVTGVSRIR AHG
Sbjct: 395 RGPGRCSAVRRRLALHLHVPDGAQRLGPGAGAQPGHHRGQRALGLALVVTGVSRIRAAHG 454

Query: 265 APGLPRAPKPSAGRGGK--EGGERGTEMLR---RLRGSPRPNRHPRSG 307
           APGLPR+P+PSAGR      G   G E LR      G P  +R P SG
Sbjct: 455 APGLPRSPQPSAGRAASPDPGEGVGNEALRCPEGCAGLPARSRRPCSG 502


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 77/312 (24%), Positives = 106/312 (33%), Gaps = 41/312 (13%)

Query: 95  PQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQ 154
           P+ P+ AP PG  + +              S S          AKR  +H + P      
Sbjct: 438 PESPKPAPAPGSHREI--------------SSSPTSKNRSHGRAKRDKSHSHTPS----- 478

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPG 214
               R   R  SP +A  G  RS   +  G  R        P W+   +    G +R P 
Sbjct: 479 ----RRMGRSRSPATAKRGRSRSRTPTKRGHSRSR-----SPQWRRSRSAQRWGRSRSPQ 529

Query: 215 RR-LALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIR-PAHGAPGLPRAP 272
           RR  +   Q P  +R    +   +    RR R+   +    G SR R PA       R P
Sbjct: 530 RRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTP 589

Query: 273 --KPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGR 330
             + S  R       R     RR R   R     RS         S     +  R+P  R
Sbjct: 590 ARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR------TRSPVRRRSRSRSPARR 643

Query: 331 GASSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQGLIFPSTGKNVQRHKSPP 390
              S +  P     SR R P +R R+R+ + AR    SGR +       G++  R     
Sbjct: 644 SGRSRSRTPARRGRSRSRTPARRGRSRSRTPARR---SGRSRSRTPARRGRSRSRTPRRG 700

Query: 391 LPSEESLSQRSR 402
                SL +R R
Sbjct: 701 RSRSRSLVRRGR 712



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 95/417 (22%), Positives = 142/417 (34%), Gaps = 46/417 (11%)

Query: 9    RDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQR------PA 62
            +D   AA   Q+   +    + PAPR        GS   G G  PE  +         P 
Sbjct: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPK 1664

Query: 63   GGKALRG-----EGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRW 117
               A RG     E + ++       +   +  ++       R+       +     PPR 
Sbjct: 1665 SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH 1724

Query: 118  VPSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRS 177
              S  P+  S + +++ R   +RR           + P     SRR  SP     G+ RS
Sbjct: 1725 RRS--PSVSSPEPAEKSRSSRRRRSA---------SSPRTKTTSRRGRSPSPKPRGLQRS 1773

Query: 178  WASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRL-----ALHLQVPEGARQLGP 232
             + S     R     D   + ++   R     +R    R        H + P  ARQ   
Sbjct: 1774 RSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP--ARQESS 1831

Query: 233  RTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLR 292
            RT ++  R R +  P         SR  PA       RA  P+  R  +      +    
Sbjct: 1832 RTSSRRRRGRSRTPPTSRK--RSRSRTSPAPWKRSRSRA-SPATHRRSRSRTPLISRRRS 1888

Query: 293  RLRGSPRPNRHPRSGPVPAHGVASAAAGPATLR-----APPGRGASSETMWPTENLSSRR 347
            R R SP   R  RS        + + A P + R      PP     S +  PT    SR 
Sbjct: 1889 RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRS 1948

Query: 348  RAPP---QRRRTRAPSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRS 401
            R PP   +R R+R P + R      R +    P T +   R ++ P+    S S+ S
Sbjct: 1949 RTPPVTRRRSRSRTPPVTRR-----RSRSRTSPITRRR-SRSRTSPVTRRRSRSRTS 1999



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 69/303 (22%), Positives = 102/303 (33%), Gaps = 37/303 (12%)

Query: 13   LAAGAGQAWGSAGRGRRG----PAPRGQTGTQGVGSGGGGAGVRPEPCAGQRPAGGKALR 68
            L++GA     S+     G    PAP       G      GA  +P   A  +PA  +   
Sbjct: 2475 LSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQ-QPSALAALQPAKERRSS 2533

Query: 69   GEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSA 128
                + ++   ++++   +   SG    D   +  P   ++ L R P   P+  P     
Sbjct: 2534 SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA--PKEAVR 2591

Query: 129  DISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQ 188
            +    +  PAKR+           +  S    S    S  S+S     S +SS +  P  
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS- 2650

Query: 189  PLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPG 248
                   P    P A     S + P          P   R   PR      R  R     
Sbjct: 2651 -------PAKPGPQALPKPASPKKPP---------PGERRSRSPRKPIDSLRDSR----- 2689

Query: 249  LALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERG-----TEMLRRLRGSPRPNRH 303
             +L  + V R RP+      PR  + S+   G   G+RG     +   RR   SPRP RH
Sbjct: 2690 -SLSYSPVERRRPSPQPS--PRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRH 2746

Query: 304  PRS 306
              S
Sbjct: 2747 RSS 2749



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 35/125 (28%), Positives = 50/125 (40%), Gaps = 11/125 (8%)

Query: 124  NSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWA 183
            +S S+  S     PAK  P     P   K  P   R SR   SPR     +  S + S++
Sbjct: 2638 SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR---SPRKPIDSLRDSRSLSYS 2694

Query: 184  GVPRQPLALDLRPT-WKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHR 242
             V R+      RP+   +P  + +  S RG  R      + P   R+       +P RHR
Sbjct: 2695 PVERR------RPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRR-RETPSPRPMRHR 2747

Query: 243  RQRAP 247
              R+P
Sbjct: 2748 SSRSP 2752


>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
           sapiens]
          Length = 1038

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 74/313 (23%), Positives = 103/313 (32%), Gaps = 75/313 (23%)

Query: 98  PRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRR---------PTHFYHP 148
           P  A PP   +  L  PP+       ++Q+A+I Q  ++   R+         P+     
Sbjct: 674 PEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGSPAPSPSPGG 733

Query: 149 DEHKAQPSHVRGSRRPGSPR-SASPGV-GRSWASSWAGV-------PRQPLALDLRPTWK 199
           D+    P  V    RP  P    SP   G    S W G        PR+PL+        
Sbjct: 734 DDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVPPREPLS-------- 785

Query: 200 APDARLALGSARGPGRRLALHLQVPEGARQLGPRT--GAQPSRHRRQRAPGLALVVTGVS 257
                                   P+G+R   P    G+ P   R   +PG  +  T   
Sbjct: 786 ------------------------PQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSF 821

Query: 258 RIRPAHGAPGLPRAPKPSAG-------RGGKEGG--------------ERGTEMLRRLRG 296
              P +  P + +AP P AG       R GK+                ER    LR  + 
Sbjct: 822 ASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQS 881

Query: 297 SPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRT 356
              P   P    +P     + AA  AT+R  P      +  + T N +   R PP R   
Sbjct: 882 PEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRATA 941

Query: 357 RAPSIARSLPGSG 369
           R P   R  PG G
Sbjct: 942 RLPQ--RGCPGDG 952


>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sapiens]
          Length = 1086

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 74/313 (23%), Positives = 103/313 (32%), Gaps = 75/313 (23%)

Query: 98   PRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRR---------PTHFYHP 148
            P  A PP   +  L  PP+       ++Q+A+I Q  ++   R+         P+     
Sbjct: 752  PEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGSPAPSPSPGG 811

Query: 149  DEHKAQPSHVRGSRRPGSPR-SASPGV-GRSWASSWAGV-------PRQPLALDLRPTWK 199
            D+    P  V    RP  P    SP   G    S W G        PR+PL+        
Sbjct: 812  DDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVPPREPLS-------- 863

Query: 200  APDARLALGSARGPGRRLALHLQVPEGARQLGPRT--GAQPSRHRRQRAPGLALVVTGVS 257
                                    P+G+R   P    G+ P   R   +PG  +  T   
Sbjct: 864  ------------------------PQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSF 899

Query: 258  RIRPAHGAPGLPRAPKPSAG-------RGGKEGG--------------ERGTEMLRRLRG 296
               P +  P + +AP P AG       R GK+                ER    LR  + 
Sbjct: 900  ASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQS 959

Query: 297  SPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRT 356
               P   P    +P     + AA  AT+R  P      +  + T N +   R PP R   
Sbjct: 960  PEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRATA 1019

Query: 357  RAPSIARSLPGSG 369
            R P   R  PG G
Sbjct: 1020 RLPQ--RGCPGDG 1030


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 101/379 (26%), Positives = 140/379 (36%), Gaps = 76/379 (20%)

Query: 22  GSAGRGRRGPA-PRGQTGTQGVGSGGGGAGVRPE--------PCAGQRP---AGGKALRG 69
           GS+  GR GP+ PRG   ++   S G  +   PE        P +   P   AGG A  G
Sbjct: 142 GSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSA--G 199

Query: 70  EGQAQAAQGYAAANGWGTVL-VSGLVPQDPRAAPPP---------GGRQL-----LLLRP 114
                +A+  A A  + T   +  +  + PR    P          GR L      LLR 
Sbjct: 200 PEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRR 259

Query: 115 PRWVPSCFPNSQ--SADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASP 172
            R   +  P +    AD     +   ++RP     P    A+P+      R G   ++  
Sbjct: 260 RRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDA-SPSPGSARPAREPSLERVGGHPTSPA 318

Query: 173 GVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGP 232
            + R+WASSW          +  P   AP A  +   +   GR   +  Q   GA+    
Sbjct: 319 ALSRAWASSWES--------EAAPEPAAPPAAPSPPDSPAEGR--LVKAQYIPGAQ---A 365

Query: 233 RTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLR 292
            T   P R  R++ P L       +R R    +P  PR    +AGR G+     G     
Sbjct: 366 ATRGLPGRAARRKPPPL-------TRGRSVEQSP--PRERPRAAGRRGRMAEASGR---- 412

Query: 293 RLRGSPRPNRHPRS-GPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPP 351
             RGSPR  +  RS       G ASA         PP         +PT      R  PP
Sbjct: 413 --RGSPRARKASRSQSETSLLGRASAVPS-----GPP--------KYPTAEREEPR--PP 455

Query: 352 QRRRTRAPSIARSLPGSGR 370
           + RR  AP++A    GS R
Sbjct: 456 RPRRGPAPTLAAQAAGSCR 474



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 102/383 (26%), Positives = 127/383 (33%), Gaps = 72/383 (18%)

Query: 1   MRGLRACSR---DLRLAAGAGQ---AWGSAGRGRRGPAPRGQTGTQGVGSGGGGA---GV 51
           MR  R C R   D   A GAG+    + SA   RR     GQ  T   G+ GG      V
Sbjct: 226 MRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSV 285

Query: 52  RPEPC------AGQRPAGGKALR---GEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAP 102
           R  P          RPA   +L    G   + AA   A A+ W +       P  P AAP
Sbjct: 286 RQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPE--PAAPPAAP 343

Query: 103 -PPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGS 161
            PP       L   +++P     +Q+A      R  A+R+P         +  P   R  
Sbjct: 344 SPPDSPAEGRLVKAQYIPG----AQAATRGLPGRA-ARRKPPPLTRGRSVEQSPPRER-- 396

Query: 162 RRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHL 221
                PR+A      + AS   G PR       R   ++      LG A           
Sbjct: 397 -----PRAAGRRGRMAEASGRRGSPRA------RKASRSQSETSLLGRASA--------- 436

Query: 222 QVPEGARQL--GPRTGAQPSRHRRQRAPGLALVVTGVSR-------IRPAHGAPGLPRAP 272
            VP G  +     R   +P R RR  AP LA    G  R       I  A G    PRAP
Sbjct: 437 -VPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAP 495

Query: 273 KPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPV----PAHGV----------ASAA 318
                  G         +L    GS       R GP+    PA GV          AS  
Sbjct: 496 AARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGESESSASEG 555

Query: 319 AGPATLRAPPGRGASSETMWPTE 341
             PA   A      S   +WP +
Sbjct: 556 ESPAFSSASSDSDGSGGLVWPQQ 578


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 86/338 (25%), Positives = 108/338 (31%), Gaps = 81/338 (23%)

Query: 26  RGRRGP-APRGQTGTQGVGSGGGGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANG 84
           +G  GP  PRG  G  G     G  G+ P P     P G   L G    Q + GY   + 
Sbjct: 114 KGDTGPRGPRGPAGPPGRDGIPGQPGL-PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKST 172

Query: 85  WGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRRPTH 144
            G  +   + P  PR  P P                                P    P  
Sbjct: 173 GGISVPGPMGPSGPRGLPGP--------------------------------PGAPGPQG 200

Query: 145 FYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDAR 204
           F  P     +P    G+  P  PR      G++     AG P +P     R       AR
Sbjct: 201 FQGPPGEPGEP----GASGPMGPRGPPGPPGKNGDDGEAGKPGRP---GERGPPGPQGAR 253

Query: 205 LALGSARGPGRRLALHLQVPEGAR----------------------QLGPRTGAQPSRHR 242
              G+A  PG +        +GA+                      Q+GPR    P    
Sbjct: 254 GLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPR--GLPGERG 311

Query: 243 RQRAPGLALVVTGVSRIRPAHGAPGL--PRAPKPSAGRGGKEG-----GERGTEMLRRLR 295
           R  APG A    G      A G PG   P  P    G  G +G     G RG+E  + +R
Sbjct: 312 RPGAPGPA-GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR 370

Query: 296 GSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGAS 333
           G P P       P PA G A  A  P     P  +GA+
Sbjct: 371 GEPGP-------PGPA-GAAGPAGNPGADGQPGAKGAN 400



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 95/332 (28%), Positives = 116/332 (34%), Gaps = 48/332 (14%)

Query: 26  RGRRGPA-PRGQTGTQGVGSGGGGAGVRPEPCAGQRPA--GGKALRGEGQAQAAQGYAAA 82
           +G  GPA P+G+ G+ G     G  G R  P    RP   G    RG   A  A G    
Sbjct: 277 KGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGP 336

Query: 83  NG-------WGTVLVSGLV-PQDPRAAPPPGGRQLLLLR----PPRWVPSCFPNSQSADI 130
            G        G V   G   PQ PR +  P G     +R    PP    +  P       
Sbjct: 337 TGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQG-----VRGEPGPPGPAGAAGPAGNPGAD 391

Query: 131 SQEDRKPAKRRPTHFYHPDEHKAQ-PSHVRGSRRPGSPR--SASPGVGRSWASSWAGVPR 187
            Q   K A   P     P    A+ PS  +G   P  P+  S  PG   S   + A    
Sbjct: 392 GQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEP 451

Query: 188 QPLALDLRPTWKAPDARLALGSARG-PGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRA 246
            P+ +   P    P        ARG PG      L  P G R  GP +   P       A
Sbjct: 452 GPVGVQGPP---GPAGEEGKRGARGEPG---PTGLPGPPGERG-GPGSRGFPG------A 498

Query: 247 PGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSP-RPNRHPR 305
            G+A    G        G+PG P  PK S G  G+  GE G    + L GSP  P    +
Sbjct: 499 DGVA----GPKGPAGERGSPG-PAGPKGSPGEAGRP-GEAGLPGAKGLTGSPGSPGPDGK 552

Query: 306 SGPVPAHGVASAAAGPATLRAPPGRGASSETM 337
           +GP P         GP     PPG    +  M
Sbjct: 553 TGP-PGPAGQDGRPGPP---GPPGARGQAGVM 580



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 114/389 (29%), Positives = 133/389 (34%), Gaps = 88/389 (22%)

Query: 22  GSAGR-GRRGP----APRGQTGTQGV----GSGG--GGAGVR--PEPCAGQRPAGGKALR 68
           G AG+ GR GP      RGQ G  G     G+ G  G AG R  P P     PAG     
Sbjct: 557 GPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD--- 613

Query: 69  GEGQAQAAQGYAAANGW-------GTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSC 121
           GE  AQ   G A   G        G+    GL    P  A PPG              + 
Sbjct: 614 GEAGAQGPPGPAGPAGERGEQGPAGSPGFQGL----PGPAGPPG-------------EAG 656

Query: 122 FPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASS 181
            P  Q          P+  R    + P E   Q     G   P  PR A+   G   A  
Sbjct: 657 KPGEQGVPGDLGAPGPSGARGERGF-PGERGVQ-----GPPGPAGPRGANGAPGNDGAKG 710

Query: 182 WAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGAR-QLGPRTGAQPSR 240
            AG P             AP ++ A G    PG R A  L  P+G R   GP+ GA  S 
Sbjct: 711 DAGAP------------GAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPK-GADGS- 756

Query: 241 HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAP--KPSAGRGGKEG--GERGTEMLRRLRG 296
                 PG      GV  +    G PG   AP  K  +G  G  G  G RG    R   G
Sbjct: 757 ------PG----KDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPG 806

Query: 297 SPRPNRHPRSGPVPAHGVASAAAGPATLRA-----PPGRGASSETMWPTENLSSRRRAPP 351
            P P     +GP  A G   A   P    A     PPG    +    P  N+     AP 
Sbjct: 807 PPGPAGF--AGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVG----APG 860

Query: 352 QR--RRTRAPSIARSLPGSGRLQGLIFPS 378
            +  R +  P  A   PG+    G   PS
Sbjct: 861 AKGARGSAGPPGATGFPGAAGRVGPPGPS 889



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 92/339 (27%), Positives = 114/339 (33%), Gaps = 71/339 (20%)

Query: 16  GAGQAWGSAGR-GRRGPAPRGQTGTQGVGSGGGGAGVRPEPCA-GQRPAGG----KALRG 69
           GA    G+AG  G +G   RG +G  G     G AG + EP + G+  A G    + L G
Sbjct: 251 GARGLPGTAGLPGMKGH--RGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG 308

Query: 70  EGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSAD 129
           E     A G A A G      +   P     A PPG                FP +  A 
Sbjct: 309 ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG----------------FPGAVGA- 351

Query: 130 ISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQP 189
                               + +A P   RGS  P   R      G + A+  AG P   
Sbjct: 352 --------------------KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP--- 388

Query: 190 LALDLRPTWKAPDARLALGSARG-PGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPG 248
              D +P  K  +    +  A G PG R       P G +  GP  G  P        PG
Sbjct: 389 -GADGQPGAKGANGAPGIAGAPGFPGAR------GPSGPQ--GP--GGPPGPKGNSGEPG 437

Query: 249 LALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEG--GERGTEMLRRLRGSPRPNRHPRS 306
                 G      A G PG P   +   G  G+EG  G RG      L G P     P S
Sbjct: 438 ----APGSKGDTGAKGEPG-PVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGS 492

Query: 307 GPVPAHGVASAAAGPATLRAPPG----RGASSETMWPTE 341
              P     +   GPA  R  PG    +G+  E   P E
Sbjct: 493 RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE 531



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 98/336 (29%), Positives = 113/336 (33%), Gaps = 75/336 (22%)

Query: 17   AGQAWGSAGRGRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQRPAGGKALRGEGQAQAA 76
            AG+  G   RG  GPA  G+ G  G     G AG +  P A   PAG     G       
Sbjct: 901  AGKEGGKGPRGETGPA--GRPGEVGPPGPPGPAGEKGSPGA-DGPAGAPGTPGP------ 951

Query: 77   QGYAAANGWGTVLVSGLVPQDPRAAPP--PGGRQLLLLRPPRWVPSCFPNSQS-ADISQE 133
            QG A   G     V GL  Q      P  PG             PS  P  Q  +  S E
Sbjct: 952  QGIAGQRG-----VVGLPGQRGERGFPGLPG-------------PSGEPGKQGPSGASGE 993

Query: 134  DRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGV----GRSWASSWAGVPRQP 189
               P    P     P     +         PG  R  SPG     G +  +   G P  P
Sbjct: 994  RGPPGPMGPPGLAGPPGESGREGAPGAEGSPG--RDGSPGAKGDRGETGPAGPPGAPGAP 1051

Query: 190  LALD-LRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPR-----TGAQPSR--- 240
             A   + P  K+ D R   G A   G    +  + P G +  GPR     TG Q  R   
Sbjct: 1052 GAPGPVGPAGKSGD-RGETGPAGPAGPVGPVGARGPAGPQ--GPRGDKGETGEQGDRGIK 1108

Query: 241  -HRR----QRAPGLALVVTGVSRIRPAHGA--PGLPRAPKPSAGRGGKEGGERGTEMLRR 293
             HR     Q  PG      G    +   GA  P  PR P  SAG  GK+G          
Sbjct: 1109 GHRGFSGLQGPPG----PPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDG---------- 1154

Query: 294  LRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPG 329
            L G P P      GP    G  +  AGP     PPG
Sbjct: 1155 LNGLPGP-----IGPPGPRG-RTGDAGPVGPPGPPG 1184



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 37/137 (27%), Positives = 44/137 (32%), Gaps = 34/137 (24%)

Query: 264 GAPGLPRAPKPSA-----GRGGKEG------------------GERGTEMLRRLRGSP-R 299
           G PGLP  P P       G GG                     G  G    R L G P  
Sbjct: 136 GQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGA 195

Query: 300 PNRHPRSGPV--PAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTR 357
           P      GP   P    AS   GP     PPG+          ++  + +   P  R   
Sbjct: 196 PGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNG--------DDGEAGKPGRPGERGPP 247

Query: 358 APSIARSLPGSGRLQGL 374
            P  AR LPG+  L G+
Sbjct: 248 GPQGARGLPGTAGLPGM 264


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 91/368 (24%), Positives = 119/368 (32%), Gaps = 63/368 (17%)

Query: 25  GRGRRGPAPRGQTGTQG-----VGSGG--GGAGVRPEPCAGQRPAGGKALRGEGQAQAAQ 77
           G+  R P P+GQ G  G     VG  G  G  G    P   Q P G +  +GE  A   +
Sbjct: 25  GQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQG----PAGEQGPRGDRGDKGEKGAPGPR 80

Query: 78  GYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKP 137
           G     G          P +P    PPG         P   P    N  +      D K 
Sbjct: 81  GRDGEPG---------TPGNPGPPGPPG---------PPGPPGLGGNFAAQMAGGFDEKA 122

Query: 138 AKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLR-- 195
                          AQ   ++G   P  PR      G      + G P +P    +   
Sbjct: 123 GG-------------AQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGP 169

Query: 196 --------PTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAP 247
                   P  K  D     G A  PG+        P+GAR   P T   P     +  P
Sbjct: 170 MGPRGPPGPPGKPGDD----GEAGKPGKAGERGPPGPQGARGF-PGTPGLPGVKGHRGYP 224

Query: 248 GL--ALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPR 305
           GL  A    G   ++   G+PG   +P P   RG    GERG        G+   +  P 
Sbjct: 225 GLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP--GERGRTGPAGAAGARGNDGQP- 281

Query: 306 SGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIARSL 365
            GP    G    A GP    AP  +G +  T       +   R  P    +  P+ A   
Sbjct: 282 -GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 340

Query: 366 PGSGRLQG 373
           PG+  + G
Sbjct: 341 PGTDGIPG 348



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 102/381 (26%), Positives = 123/381 (32%), Gaps = 101/381 (26%)

Query: 14  AAGAGQAWGSAGR----GRRGP----------APRGQTGTQGVGSGGGGAGVRPEPCAGQ 59
           A G+  A G AG     G RGP           P+GQTG  G+    G  G + EP    
Sbjct: 349 AKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP---- 404

Query: 60  RPAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVP 119
            PAG +   G    +  +G     G     V  + P   R AP   G             
Sbjct: 405 GPAGPQGAPGPAGEEGKRGARGEPGG----VGPIGPPGERGAPGNRG------------- 447

Query: 120 SCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGS------PRSASP- 172
             FP      ++     P +R P+    P      P        PG+      P  A P 
Sbjct: 448 --FPGQDG--LAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQ 503

Query: 173 -GVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQL- 230
             VG S A    G P  P     R            G+   PG+     L    G R L 
Sbjct: 504 GKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLP 563

Query: 231 ---------GPRTGAQPSRHR-RQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGG 280
                    GP   A P+  R  Q APG               G  GLP  P P  G GG
Sbjct: 564 GKDGETGAAGPPGPAGPAGERGEQGAPG-------------PSGFQGLPGPPGP-PGEGG 609

Query: 281 KEG-----------------------GERGTEMLRRLRGSPR--PNRHPRSGPVPAHGVA 315
           K G                       GERG+   + L+G PR  P      GP  A G A
Sbjct: 610 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG-PRGLPGTPGTDGPKGASGPA 668

Query: 316 S--AAAGPATLRAPPG-RGAS 333
               A GP  L+  PG RGA+
Sbjct: 669 GPPGAQGPPGLQGMPGERGAA 689



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 99/423 (23%), Positives = 131/423 (30%), Gaps = 81/423 (19%)

Query: 18  GQAWGSAGRGRRG-PAPRGQTGTQGVGSGGG-----GAGVRPEPCAGQRPAGGKALRGEG 71
           G A  +  RG  G P P G  G  G   G G     GA     P   + P G +  RGE 
Sbjct: 267 GPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEP 326

Query: 72  QAQAAQGYAAANG----------WGTVLVSGLV----------PQDPRAAPPPGGRQLLL 111
               + G A A+G           G+    G+           P  P+ A  P G +   
Sbjct: 327 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 386

Query: 112 LRP----------PRWVPS-CFPNSQSADISQEDRKPAKRRP----------------TH 144
             P          P+  P    P        +E ++ A+  P                  
Sbjct: 387 GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNR 446

Query: 145 FYHPDEHKAQPSHVRGSRRP---GSPRSASPGVGRSWASSWAGVPRQPLALDL--RPTWK 199
            +   +  A P    G R P     P+ A+   GR       G P  P A  L  RP   
Sbjct: 447 GFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR------PGEPGLPGARGLTGRPGDA 500

Query: 200 APDARLALGSARGPGRRLALHLQVPEGARQL-------GPR-TGAQPSRHRRQRAPGLAL 251
            P  +  +G +  PG         P+GAR         GP+    +P +   +  PG   
Sbjct: 501 GPQGK--VGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPG--- 555

Query: 252 VVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPA 311
              G+  +    G  G    P P+   G  E GE+G       +G P P   P  G  P 
Sbjct: 556 -APGLRGLPGKDGETGAAGPPGPAGPAG--ERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 612

Query: 312 -HGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGR 370
             GV   A  P  +     RG   E   P        R  P    T  P  A    G   
Sbjct: 613 DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPG 672

Query: 371 LQG 373
            QG
Sbjct: 673 AQG 675



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 89/320 (27%), Positives = 108/320 (33%), Gaps = 61/320 (19%)

Query: 17   AGQAWGSAGRGRRGP----APRGQTGTQGVGSGGGGAGVRPEPCAGQRPAGGKALRGEGQ 72
            AG+       G  GP     P G+ G +G     G  G   EP   Q PAG    +GE  
Sbjct: 833  AGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL-QGPAGPPGEKGEPG 891

Query: 73   AQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQ 132
                 G     G       GL  Q      P  G++     P    PS  P  Q A  + 
Sbjct: 892  DDGPSGAEGPPG-----PQGLAGQRGIVGLP--GQRGERGFPGLPGPSGEPGKQGAPGAS 944

Query: 133  EDR-KPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLA 191
             DR  P    P     P     +P       R GSP +  P  GR  A+   G       
Sbjct: 945  GDRGPPGPVGPPGLTGP---AGEPG------REGSPGADGPP-GRDGAAGVKG------- 987

Query: 192  LDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLAL 251
             D   T        A+G+   PG         P G+      TG Q  R        +  
Sbjct: 988  -DRGETG-------AVGAPGAPG---------PPGSPGPAGPTGKQGDRGEAGAQGPMG- 1029

Query: 252  VVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEG--GERGTEMLRRLRGSPRPNRHPRSGPV 309
              +G +  R   G  G PR  K  AG  G+ G  G RG   L+ L G P        GP 
Sbjct: 1030 -PSGPAGARGIQGPQG-PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP--------GPS 1079

Query: 310  PAHGVASAAAGPATLRAPPG 329
               G AS  AGP+  R PPG
Sbjct: 1080 GDQG-ASGPAGPSGPRGPPG 1098



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 34/105 (32%), Positives = 41/105 (39%), Gaps = 10/105 (9%)

Query: 13   LAAGAGQAWGSAGRGRRGPAPR-GQTGTQGVG--SGGGGAGVRPEPCAGQRPAGGKALRG 69
            L   AG+       G  GP  R G  G +G    +G  GA   P P     PAG    +G
Sbjct: 958  LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017

Query: 70   EGQAQAAQGYAAANG-WGTVLVSGLVPQDPRA----APPPGGRQL 109
            +     AQG    +G  G   + G  PQ PR     A  PG R L
Sbjct: 1018 DRGEAGAQGPMGPSGPAGARGIQG--PQGPRGDKGEAGEPGERGL 1060


>gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 114/445 (25%), Positives = 149/445 (33%), Gaps = 80/445 (17%)

Query: 2   RGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTG---TQGVGSGGGGAGVRPEPCAG 58
           R  RA    L  A  A    G+   G  GPAP        TQ   SGGGG G    P AG
Sbjct: 109 RSRRAAGPGLDCAGSAPAPSGAQSCG--GPAPASALRRPLTQWDASGGGGRGSHSGPRAG 166

Query: 59  QRPAGGKALRG----------------EGQAQAAQGYAAANGWGTVLVSGLVPQDPRA-- 100
             P GG++ R                 +G ++  QG  ++  WG    SG  P  PRA  
Sbjct: 167 -TPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSS--WGG---SG-TPPPPRALW 219

Query: 101 ---APPPGGRQLLLLRPPRWVP-SCFPNSQ--SADISQEDRKPAKRRPTHFYHPDEHKAQ 154
                  G R  +     R  P S  P S   +  +    R     +   F  P  H   
Sbjct: 220 NRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTS 279

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPG 214
                G R  G   S  P +  S A+  + +P   +A    P+  A   RL  G  +   
Sbjct: 280 -----GGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTV 334

Query: 215 RRLALHLQV-------PEGARQLGPRTGAQP-SRHRRQRAPGLALVVTGVSRIRPAHGAP 266
            + A+   +       P   R L P  G++  +R  R      A  +   SR RP   AP
Sbjct: 335 LKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAP 394

Query: 267 GLPRAPKPSAGRGGKEGGER--------------GTEMLRRLRGSPRPNRHPRSGPVPAH 312
                P    G GG  G  +              GT  L   RGS  P        VP  
Sbjct: 395 RGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHF 454

Query: 313 GVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRA-PSIARSLP----- 366
              S+ A  +  R+P  R            L + R + PQ  R  A P IA   P     
Sbjct: 455 RPLSSPAPQSPPRSPSVRAFG-------PRLGAGRLSCPQAPRAAALPGIAVLAPSPAHD 507

Query: 367 -GSGRLQGL---IFPSTGKNVQRHK 387
            G  R +G      P  G+  +R K
Sbjct: 508 WGGQRCEGCGGGSQPFAGRRAERGK 532


>gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 114/445 (25%), Positives = 149/445 (33%), Gaps = 80/445 (17%)

Query: 2   RGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTG---TQGVGSGGGGAGVRPEPCAG 58
           R  RA    L  A  A    G+   G  GPAP        TQ   SGGGG G    P AG
Sbjct: 109 RSRRAAGPGLDCAGSAPAPSGAQSCG--GPAPASALRRPLTQWDASGGGGRGSHSGPRAG 166

Query: 59  QRPAGGKALRG----------------EGQAQAAQGYAAANGWGTVLVSGLVPQDPRA-- 100
             P GG++ R                 +G ++  QG  ++  WG    SG  P  PRA  
Sbjct: 167 -TPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSS--WGG---SG-TPPPPRALW 219

Query: 101 ---APPPGGRQLLLLRPPRWVP-SCFPNSQ--SADISQEDRKPAKRRPTHFYHPDEHKAQ 154
                  G R  +     R  P S  P S   +  +    R     +   F  P  H   
Sbjct: 220 NRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTS 279

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPG 214
                G R  G   S  P +  S A+  + +P   +A    P+  A   RL  G  +   
Sbjct: 280 -----GGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTV 334

Query: 215 RRLALHLQV-------PEGARQLGPRTGAQP-SRHRRQRAPGLALVVTGVSRIRPAHGAP 266
            + A+   +       P   R L P  G++  +R  R      A  +   SR RP   AP
Sbjct: 335 LKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAP 394

Query: 267 GLPRAPKPSAGRGGKEGGER--------------GTEMLRRLRGSPRPNRHPRSGPVPAH 312
                P    G GG  G  +              GT  L   RGS  P        VP  
Sbjct: 395 RGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHF 454

Query: 313 GVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRA-PSIARSLP----- 366
              S+ A  +  R+P  R            L + R + PQ  R  A P IA   P     
Sbjct: 455 RPLSSPAPQSPPRSPSVRAFG-------PRLGAGRLSCPQAPRAAALPGIAVLAPSPAHD 507

Query: 367 -GSGRLQGL---IFPSTGKNVQRHK 387
            G  R +G      P  G+  +R K
Sbjct: 508 WGGQRCEGCGGGSQPFAGRRAERGK 532


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 89/364 (24%), Positives = 114/364 (31%), Gaps = 66/364 (18%)

Query: 20  AWGSAGRGRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGY 79
           A G+ G      +P G  G        G  G  PEP     P  G+A  G G  Q     
Sbjct: 54  AAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEP-----PPAGRARPGGGGPQRP--- 105

Query: 80  AAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAK 139
              +    ++ +G  P   +  PPP G             SC P   +A ++    +PA 
Sbjct: 106 GPPSPRRPLVPAGPAPPAAKLRPPPEGS----------AGSCAPVPAAAAVA-AGPEPAP 154

Query: 140 RRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWK 199
             P          A P+ +     PG      PG G          P +P       T  
Sbjct: 155 AGPA-------KPAGPAALAARAGPGPGPGPGPGPGPG--------PGKPAGPGAAQTLN 199

Query: 200 APDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGV--S 257
              A L    A  P   L     V  G   L P          +  APG  +       +
Sbjct: 200 GSAALLNSHHAAAPAVSL-----VNNGPAALLPLP--------KPAAPGTVIQTPPFVGA 246

Query: 258 RIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPR--PNRHPRSGPV------ 309
              PA  AP  P AP P+A              L R  G P   P   P   P       
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306

Query: 310 ----PAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIARSL 365
                A   A AA GPA +   PG GA++    P     S     P+R    AP  A++L
Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAES-----PKRVVQAAPPAAQTL 361

Query: 366 PGSG 369
             SG
Sbjct: 362 AASG 365


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 99/394 (25%), Positives = 125/394 (31%), Gaps = 85/394 (21%)

Query: 26  RGRRGP-APRGQTGTQGVGSGGG-GAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAAN 83
           RGR GP  PRG+ G  G G  G  GA   P P       G    +G   +   QG     
Sbjct: 623 RGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPV 682

Query: 84  GW----GTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAK 139
           G     G V + G V  D     PPG +     + PR +                 +P  
Sbjct: 683 GLQGLRGEVGLPG-VKGDKGPMGPPGPKGDQGEKGPRGLTG---------------EPGM 726

Query: 140 RR-PTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTW 198
           R  P     P          +G+  P  P       G    +   G+   P         
Sbjct: 727 RGLPGAVGEPG--------AKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPP--------- 769

Query: 199 KAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSR 258
                    G +  PG+      Q P+G     P T  +P       APG  +   G S 
Sbjct: 770 ---------GPSGDPGKPGLTGPQGPQGL----PGTPGRPGIKGEPGAPGKIVTSEGSSM 816

Query: 259 IRP--------AHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVP 310
           +          A G PG P AP P AG  G  G +     +  L+G P P   PR  P P
Sbjct: 817 LTVPGPPGPPGAMGPPGPPGAPGP-AGPAGLPGHQE----VLNLQGPPGPPG-PRGPPGP 870

Query: 311 AHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRR---------APPQRRRTRAPSI 361
           +        GP   R PPG G       P   LS+             PP  +  + P  
Sbjct: 871 S------IPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG 924

Query: 362 ARSLPGSGRLQGLI---FPSTGKNVQRHKSPPLP 392
            R   G   L G       S G N+Q    PP P
Sbjct: 925 PRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGP 958



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 85/323 (26%), Positives = 102/323 (31%), Gaps = 54/323 (16%)

Query: 22  GSAG-RGRRGPAP----RGQTGTQGVGSGGGGAGVRPEPCAGQRPAGGKALRGEGQAQAA 76
           GS G +G  GP      RG+ G  GV    G  G  P P   Q   G + L GE   +  
Sbjct: 671 GSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGP-PGPKGDQGEKGPRGLTGEPGMRGL 729

Query: 77  QGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRK 136
            G     G        + P  P     P G Q L   P    P       S D       
Sbjct: 730 PGAVGEPG----AKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPP----GPSGD------- 774

Query: 137 PAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRP 196
           P K   T    P      P        PG+P       G    SS   VP  P       
Sbjct: 775 PGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEG----SSMLTVPGPPGPPGAMG 830

Query: 197 TWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGV 256
               P A    G A  PG +  L+LQ P G    GPR    PS       PG        
Sbjct: 831 PPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPP--GPRGPPGPSI---PGPPG-------- 877

Query: 257 SRIRPAHGAPGLPRAPKPS--------AGRGGKEG--GERGTEMLRRLRGSPRPNRHPRS 306
            R  P  G PG P  P           +G  G  G  G +G +      G P P  H   
Sbjct: 878 PRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQ------GPPGPRGHQGE 931

Query: 307 GPVPAHGVASAAAGPATLRAPPG 329
             +P    + +++    L+ PPG
Sbjct: 932 QGLPGFSTSGSSSFGLNLQGPPG 954



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 30/90 (33%), Positives = 37/90 (41%), Gaps = 11/90 (12%)

Query: 26   RGRRGP-APRGQTGTQGV------GSGGGGAGVR--PEPCAGQRPAGGKALRG-EGQAQA 75
            +G +GP  PRG  G QG+      GS   G  ++  P P   Q P G K   G  G    
Sbjct: 917  KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGI 976

Query: 76   AQGYAAANGWGTVLVSGLVPQDPRAAPPPG 105
              G +      T+ VSG  P  P    PPG
Sbjct: 977  PSGPSEGGSSSTMYVSG-PPGPPGPPGPPG 1005



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 8/80 (10%)

Query: 13   LAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGGGA------GVRPEPCAGQRPAGGKA 66
            L+  A  + GS+         RG + +  + +GGGGA      G   E    + P G   
Sbjct: 1282 LSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDI 1341

Query: 67   LRGEGQAQAAQG--YAAANG 84
              G G   AA+G  YA   G
Sbjct: 1342 GPGGGYGAAAEGGMYAGNGG 1361


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 94/386 (24%), Positives = 122/386 (31%), Gaps = 76/386 (19%)

Query: 7   CSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQG-----VGSGG--GGAGVRPEPCAGQ 59
           C  DL  A+G              P P+GQ G  G     VG  G  G  G    P   Q
Sbjct: 89  CPTDLATASGQ-------------PGPKGQKGEPGDIKDIVGPKGPPGPQG----PAGEQ 131

Query: 60  RPAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVP 119
            P G +  +GE  A   +G     G          P +P    PPG         P   P
Sbjct: 132 GPRGDRGDKGEKGAPGPRGRDGEPG---------TPGNPGPPGPPG---------PPGPP 173

Query: 120 SCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWA 179
               N  +      D K                AQ   ++G   P  PR      G    
Sbjct: 174 GLGGNFAAQMAGGFDEKAGG-------------AQLGVMQGPMGPMGPRGPPGPAGAPGP 220

Query: 180 SSWAGVPRQPLALDLR----------PTWKAPDARLALGSARGPGRRLALHLQVPEGARQ 229
             + G P +P    +           P  K  D     G A  PG+        P+GAR 
Sbjct: 221 QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDD----GEAGKPGKAGERGPPGPQGARG 276

Query: 230 LGPRTGAQPSRHRRQRAPGL--ALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERG 287
             P T   P     +  PGL  A    G   ++   G+PG   +P P   RG    GERG
Sbjct: 277 F-PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP--GERG 333

Query: 288 TEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRR 347
                   G+   +  P  GP    G    A GP    AP  +G +  T       +   
Sbjct: 334 RTGPAGAAGARGNDGQP--GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 391

Query: 348 RAPPQRRRTRAPSIARSLPGSGRLQG 373
           R  P    +  P+ A   PG+  + G
Sbjct: 392 RGEPGTPGSPGPAGASGNPGTDGIPG 417



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 102/381 (26%), Positives = 123/381 (32%), Gaps = 101/381 (26%)

Query: 14  AAGAGQAWGSAGR----GRRGP----------APRGQTGTQGVGSGGGGAGVRPEPCAGQ 59
           A G+  A G AG     G RGP           P+GQTG  G+    G  G + EP    
Sbjct: 418 AKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP---- 473

Query: 60  RPAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVP 119
            PAG +   G    +  +G     G     V  + P   R AP   G             
Sbjct: 474 GPAGPQGAPGPAGEEGKRGARGEPGG----VGPIGPPGERGAPGNRG------------- 516

Query: 120 SCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGS------PRSASP- 172
             FP      ++     P +R P+    P      P        PG+      P  A P 
Sbjct: 517 --FPGQDG--LAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQ 572

Query: 173 -GVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQL- 230
             VG S A    G P  P     R            G+   PG+     L    G R L 
Sbjct: 573 GKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLP 632

Query: 231 ---------GPRTGAQPSRHR-RQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGG 280
                    GP   A P+  R  Q APG               G  GLP  P P  G GG
Sbjct: 633 GKDGETGAAGPPGPAGPAGERGEQGAPG-------------PSGFQGLPGPPGP-PGEGG 678

Query: 281 KEG-----------------------GERGTEMLRRLRGSPR--PNRHPRSGPVPAHGVA 315
           K G                       GERG+   + L+G PR  P      GP  A G A
Sbjct: 679 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQG-PRGLPGTPGTDGPKGASGPA 737

Query: 316 S--AAAGPATLRAPPG-RGAS 333
               A GP  L+  PG RGA+
Sbjct: 738 GPPGAQGPPGLQGMPGERGAA 758



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 89/320 (27%), Positives = 108/320 (33%), Gaps = 61/320 (19%)

Query: 17   AGQAWGSAGRGRRGP----APRGQTGTQGVGSGGGGAGVRPEPCAGQRPAGGKALRGEGQ 72
            AG+       G  GP     P G+ G +G     G  G   EP   Q PAG    +GE  
Sbjct: 902  AGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL-QGPAGPPGEKGEPG 960

Query: 73   AQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQ 132
                 G     G       GL  Q      P  G++     P    PS  P  Q A  + 
Sbjct: 961  DDGPSGAEGPPG-----PQGLAGQRGIVGLP--GQRGERGFPGLPGPSGEPGKQGAPGAS 1013

Query: 133  EDR-KPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLA 191
             DR  P    P     P     +P       R GSP +  P  GR  A+   G       
Sbjct: 1014 GDRGPPGPVGPPGLTGP---AGEPG------REGSPGADGPP-GRDGAAGVKG------- 1056

Query: 192  LDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLAL 251
             D   T        A+G+   PG         P G+      TG Q  R        +  
Sbjct: 1057 -DRGETG-------AVGAPGAPG---------PPGSPGPAGPTGKQGDRGEAGAQGPMG- 1098

Query: 252  VVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEG--GERGTEMLRRLRGSPRPNRHPRSGPV 309
              +G +  R   G  G PR  K  AG  G+ G  G RG   L+ L G P        GP 
Sbjct: 1099 -PSGPAGARGIQGPQG-PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP--------GPS 1148

Query: 310  PAHGVASAAAGPATLRAPPG 329
               G AS  AGP+  R PPG
Sbjct: 1149 GDQG-ASGPAGPSGPRGPPG 1167



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 34/105 (32%), Positives = 41/105 (39%), Gaps = 10/105 (9%)

Query: 13   LAAGAGQAWGSAGRGRRGPAPR-GQTGTQGVG--SGGGGAGVRPEPCAGQRPAGGKALRG 69
            L   AG+       G  GP  R G  G +G    +G  GA   P P     PAG    +G
Sbjct: 1027 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086

Query: 70   EGQAQAAQGYAAANG-WGTVLVSGLVPQDPRA----APPPGGRQL 109
            +     AQG    +G  G   + G  PQ PR     A  PG R L
Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQG--PQGPRGDKGEAGEPGERGL 1129


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 85/320 (26%), Positives = 106/320 (33%), Gaps = 76/320 (23%)

Query: 22  GSAG-RGRRG----PAPRGQTGTQGVGSGGGGAGVRPEPCAGQR----PAGGKALRGEGQ 72
           G AG RG  G    P P+G TG  G     G AG+     AG R    P G    +G   
Sbjct: 481 GPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGL-----AGARGAPGPDGNNGAQGPPG 535

Query: 73  AQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQ 132
            Q  QG     G                  PPG        PP +     P+  + ++  
Sbjct: 536 PQGVQGGKGEQG------------------PPG--------PPGFQGLPGPSGPAGEVG- 568

Query: 133 EDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLAL 192
              KP +R      H +     P+  RG R P     A+   G   +   +G P      
Sbjct: 569 ---KPGERG----LHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPP------ 615

Query: 193 DLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQ--PSRHRRQRAPGLA 250
                   PD     G+   PG   A+    P G   L    GA   P     +  PGL 
Sbjct: 616 -------GPD-----GNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLR 663

Query: 251 LVVTGVSRIRPAHGAPGLPRAPKPSAGRGGK-EGGERGTEMLRRLRGSPRPNRHPRSGPV 309
             +    R   A GAPG   AP P+   G + E G  G       RGS  P      GP 
Sbjct: 664 GEIGNPGR-DGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGS--PGERGEVGPA 720

Query: 310 PAHGVASAAAGPATLRAPPG 329
             +G     AGPA     PG
Sbjct: 721 GPNGF----AGPAGAAGQPG 736



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 105/396 (26%), Positives = 127/396 (32%), Gaps = 87/396 (21%)

Query: 31  PAPRGQTGTQGVGSG------GGGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANG 84
           P P G  G  G+G        G G G+ P P     P G     G    Q  QG A    
Sbjct: 62  PGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGE-- 119

Query: 85  WGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAK-RRPT 143
                     P +P    P G R           P+  P       + ED  P K  RP 
Sbjct: 120 ----------PGEPGQTGPAGARG----------PAGPPGK-----AGEDGHPGKPGRP- 153

Query: 144 HFYHPDEHKAQPSHVRGSRRPGSPRSASPGV-GRSWASSWAGVPRQPLALDLRPTWKAPD 202
                +     P   RG   PG+P    PG  G    +   G+  QP A  ++    AP 
Sbjct: 154 ----GERGVVGPQGARGF--PGTP--GLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPG 205

Query: 203 ARLALG--SARG-PGRRLALHLQVPEGAR----QLGPRTGAQPSRHRR----QRAPGLAL 251
                G   ARG PG R  +    P GAR     +GP   A P           APG   
Sbjct: 206 ENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKG 265

Query: 252 VVTGVSRIRPAH--------GAPGL--PRAPKPSAGRGGKEG--GERGTEMLRRLRGSPR 299
            +  V    PA         G PGL  P  P  + G  G  G  G  G   +    G P 
Sbjct: 266 EIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPG 325

Query: 300 PNRHPRSGPVPAHGVASAAA-----GPATLRAPPGR-------------GASSETMWPTE 341
           P   P  GPV A G   A       GPA  +   G              G S E      
Sbjct: 326 PRGIP--GPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGP 383

Query: 342 NLSSRRRAPPQRRRTRAPSIARSLPGSGRLQGLIFP 377
           N  +    PP     R    +R LPG+    G++ P
Sbjct: 384 NGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGP 419



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 88/315 (27%), Positives = 113/315 (35%), Gaps = 57/315 (18%)

Query: 22   GSAGR-GRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQR-PAGGKALRGEGQAQAAQGY 79
            G AG+ G RGP  RG  G   VG  G    V P   AG++ P+G     G       QG 
Sbjct: 811  GPAGKEGLRGP--RGDQGP--VGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGL 866

Query: 80   AAANGW----------GTVLVSGLV--PQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQS 127
              A G           G   V+G V  P     A PPG R      PP  V S   N   
Sbjct: 867  LGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARG-----PPGAVGSPGVNGAP 921

Query: 128  ADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPR 187
             +  + D  P    P           QP H +G R  G P +  P VG + A    G P 
Sbjct: 922  GEAGR-DGNPGNDGPPG------RDGQPGH-KGER--GYPGNIGP-VGAAGAPGPHG-PV 969

Query: 188  QPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAP 247
             P           P   +    A GP        + P G + +    G +P     +  P
Sbjct: 970  GPAGKHGNRGETGPSGPVGPAGAVGP--------RGPSGPQGIRGDKG-EPGEKGPRGLP 1020

Query: 248  GLA-----LVVTGVSRIRPAHGAPGL-----PRAPKPSAGRGGKEG--GERGTEMLRRLR 295
            GL        + G++      GAPG      PR P   +G  GK+G  G  GT     +R
Sbjct: 1021 GLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIR 1080

Query: 296  GSPRPNRHPRSGPVP 310
            G P+ ++ P   P P
Sbjct: 1081 G-PQGHQGPAGPPGP 1094


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 96/384 (25%), Positives = 118/384 (30%), Gaps = 65/384 (16%)

Query: 3    GLRACSRDLRLAAGAGQAWGSAGRGRRGP-APRGQTGTQGVGSGGGGAGV--RPEPCAGQ 59
            GLR    D  L    G        G  GP  P G  G +G     G  G+  RP P    
Sbjct: 1054 GLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPP 1113

Query: 60   RPAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVP 119
             PAG K   GE   +  QG A  +G           Q P   P P G     + PP    
Sbjct: 1114 GPAGEKGAPGE---KGPQGPAGRDGL----------QGPVGLPGPAGP----VGPPG--- 1153

Query: 120  SCFPNSQSADISQEDRKPAK-----RRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGV 174
                +    +I +  +K +K     + P     P     QP        PG PR      
Sbjct: 1154 ---EDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG-PRGQQGLF 1209

Query: 175  GRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGA----RQL 230
            G+       G P  P  + L+     P  +   G     G       + P GA       
Sbjct: 1210 GQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQ 1269

Query: 231  GPRTG-AQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTE 289
            GP  G   P     +  PG A             G PGLP    P   +G  E GE+G  
Sbjct: 1270 GPPGGIGNPGAVGEKGEPGEA-------------GEPGLPGEGGPPGPKG--ERGEKGES 1314

Query: 290  MLRRLRGSPRPNRHP-------RSGPV--PAHGVASAAAGPATLRAPPG----RGASSET 336
                  G P P   P         GPV  P         GPA    PPG     G   +T
Sbjct: 1315 GPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQT 1374

Query: 337  MWPTENLSSRRRAPPQRRRTRAPS 360
              P          PP +R    P+
Sbjct: 1375 GSPGPTGEPGPSGPPGKRGPPGPA 1398



 Score = 35.8 bits (81), Expect = 0.070
 Identities = 74/298 (24%), Positives = 93/298 (31%), Gaps = 52/298 (17%)

Query: 25   GRGRRG-PAPRGQTGTQGVGSGGGGAGVRPEP-----CAGQRPAGGKALRGEGQAQAAQG 78
            GRG  G P PRGQ G  G     G  G+  +P       G  PAG    RG    Q   G
Sbjct: 899  GRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTG 958

Query: 79   YAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPA 138
            +                  P+  P P G+  L   P +   + F             K  
Sbjct: 959  FPG----------------PKGPPGPPGKDGLPGHPGQRGETGFQG-----------KTG 991

Query: 139  KRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPG-VGRSWASSWAGVPRQPLALDLRPT 197
               P     P     +   +     PG P    PG  G    +   G    P    L   
Sbjct: 992  PPGPPGVVGPQGPTGETGPMGERGHPGPP--GPPGEQGLPGLAGKEGTKGDPGPAGLPGK 1049

Query: 198  WKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVS 257
               P  R   G    PG   AL L+  E     GP     P+    +R P  A    G+ 
Sbjct: 1050 DGPPGLRGFPGDRGLPGPVGALGLKGNE-----GPPGPPGPAGSPGERGPAGAAGPIGI- 1103

Query: 258  RIRPAHGAPGLPRAPKPSAGRGGKEG--GERGTEMLRRLRGSPRPNRHPRSGPVPAHG 313
               P    P  P  P    G  G++G  G  G + L+   G P P     +GPV   G
Sbjct: 1104 ---PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGP-----AGPVGPPG 1153



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 8/89 (8%)

Query: 18   GQAWGSAGRGRRGP-APRGQTGTQGVGSGGGGAGVRPEPCAGQRPAGGKALRGEGQAQAA 76
            G+   S   G+RGP  P G  G QG     G AG+   P     P G +   G+      
Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPP-GKTGPIGPQGAPGKPGPDGL 1439

Query: 77   QGYAAANGWGTVLVSGLVPQDPRAAPPPG 105
            +G       G V   GL P  P    PPG
Sbjct: 1440 RGIP-----GPVGEQGL-PGSPGPDGPPG 1462


>gi|239756845 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 257

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 64/251 (25%), Positives = 85/251 (33%), Gaps = 63/251 (25%)

Query: 25  GRGRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANG 84
           G G   P P G    +G  +GGGG G+     + QR AG  A R  G A +        G
Sbjct: 20  GDGDEAPGPGGG---EGAAAGGGGGGLGSGGRSAQRRAGAGARRPIGAAPSVGPGGELQG 76

Query: 85  WGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSC---FPNSQSADISQEDRKPAKR- 140
           WG    SG  P  P      GGR+L    PPR   +     P +Q+A   +  R P+ R 
Sbjct: 77  WGR--KSGCRPPGPEGW--AGGRKLRRWLPPRRFSNFCCRSPCAQTAVRRRRRRAPSPRG 132

Query: 141 -----------------------------------RPTHFYHPDEHKAQPSHVRGSRR-- 163
                                               P H    +  +A+P   R  RR  
Sbjct: 133 AGWREGAGAGRGTPATMAGGEWAAEPLHLPQRGRPAPLHLPEREATEARPRRRRARRRLR 192

Query: 164 ---PGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGP------G 214
              P  P     G+GR W     G+    L   +   + AP       +AR P      G
Sbjct: 193 VLEPHPPARLGRGIGRVWVK---GITAWGLEGHI---FSAPRISATASTARRPTVVQRWG 246

Query: 215 RRLALHLQVPE 225
            R A   +VP+
Sbjct: 247 ARAAFPSRVPD 257


>gi|169211031 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 257

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 64/251 (25%), Positives = 85/251 (33%), Gaps = 63/251 (25%)

Query: 25  GRGRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANG 84
           G G   P P G    +G  +GGGG G+     + QR AG  A R  G A +        G
Sbjct: 20  GDGDEAPGPGGG---EGAAAGGGGGGLGSGGRSAQRRAGAGARRPIGAAPSVGPGGELQG 76

Query: 85  WGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSC---FPNSQSADISQEDRKPAKR- 140
           WG    SG  P  P      GGR+L    PPR   +     P +Q+A   +  R P+ R 
Sbjct: 77  WGR--KSGCRPPGPEGW--AGGRKLRRWLPPRRFSNFCCRSPCAQTAVRRRRRRAPSPRG 132

Query: 141 -----------------------------------RPTHFYHPDEHKAQPSHVRGSRR-- 163
                                               P H    +  +A+P   R  RR  
Sbjct: 133 AGWREGAGAGRGTPATMAGGEWAAEPLHLPQRGRPAPLHLPEREATEARPRRRRARRRLR 192

Query: 164 ---PGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGP------G 214
              P  P     G+GR W     G+    L   +   + AP       +AR P      G
Sbjct: 193 VLEPHPPARLGRGIGRVWVK---GITAWGLEGHI---FSAPRISATASTARRPTVVQRWG 246

Query: 215 RRLALHLQVPE 225
            R A   +VP+
Sbjct: 247 ARAAFPSRVPD 257


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 104/418 (24%), Positives = 139/418 (33%), Gaps = 99/418 (23%)

Query: 16  GAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGGG---------AGV--------RPEPCAG 58
           GAG   G  G G  G    G  G  G   GGGG         AG+        R     G
Sbjct: 64  GAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGG 123

Query: 59  QRPAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWV 118
            RP     L   G++ +A+ ++  +G G   V        R+ PP   R    + PPR  
Sbjct: 124 SRP---PLLPPGGRSTSAKPFSPPSGPGRFPVPS---PGHRSGPPEPQRN--RMPPPR-- 173

Query: 119 PSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRR-PGSPRSASPGV--- 174
               P+  S   S     P+  RP              H RGS   PG PR  SPG    
Sbjct: 174 ----PDVGSKPDSIPPPVPSTPRPIQ---------SSPHNRGSPPVPGGPRQPSPGPTPP 220

Query: 175 ----GRSWASSWAGVPRQPLA----LDLRPTWKAPDARLALGSARGP-----GRRLALHL 221
                R  A     + + PL+       RP      +R AL     P     G R ++H 
Sbjct: 221 PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR-ALDDKPPPPPPPVGNRPSIHR 279

Query: 222 QV--PEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRG 279
           +   P   +   P   + P      +AP             P    PG P  P P +  G
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPP----------PPPSRPGPP--PLPPSSSG 327

Query: 280 GKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWP 339
             E        L     +P      RSGP+P      +   P  +R PPGR         
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPP---PPSERPPPPVRDPPGRSGP------ 378

Query: 340 TENLSSRRRAPPQRRRTRAPSIARSLPGSGRL---QGLIFPSTGKNVQRHKSPPLPSE 394
                     PP    +R  S +R+LP + +L    G+  P +G        PPLP +
Sbjct: 379 ---------LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR------PPLPPD 421


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 104/418 (24%), Positives = 139/418 (33%), Gaps = 99/418 (23%)

Query: 16  GAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGGG---------AGV--------RPEPCAG 58
           GAG   G  G G  G    G  G  G   GGGG         AG+        R     G
Sbjct: 64  GAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGG 123

Query: 59  QRPAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWV 118
            RP     L   G++ +A+ ++  +G G   V        R+ PP   R    + PPR  
Sbjct: 124 SRP---PLLPPGGRSTSAKPFSPPSGPGRFPVPS---PGHRSGPPEPQRN--RMPPPR-- 173

Query: 119 PSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRR-PGSPRSASPGV--- 174
               P+  S   S     P+  RP              H RGS   PG PR  SPG    
Sbjct: 174 ----PDVGSKPDSIPPPVPSTPRPIQ---------SSPHNRGSPPVPGGPRQPSPGPTPP 220

Query: 175 ----GRSWASSWAGVPRQPLA----LDLRPTWKAPDARLALGSARGP-----GRRLALHL 221
                R  A     + + PL+       RP      +R AL     P     G R ++H 
Sbjct: 221 PFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR-ALDDKPPPPPPPVGNRPSIHR 279

Query: 222 QV--PEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRG 279
           +   P   +   P   + P      +AP             P    PG P  P P +  G
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPP----------PPPSRPGPP--PLPPSSSG 327

Query: 280 GKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWP 339
             E        L     +P      RSGP+P      +   P  +R PPGR         
Sbjct: 328 NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPP---PPSERPPPPVRDPPGRSGP------ 378

Query: 340 TENLSSRRRAPPQRRRTRAPSIARSLPGSGRL---QGLIFPSTGKNVQRHKSPPLPSE 394
                     PP    +R  S +R+LP + +L    G+  P +G        PPLP +
Sbjct: 379 ---------LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR------PPLPPD 421


>gi|13129104 coiled-coil domain containing 86 [Homo sapiens]
          Length = 360

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 57/231 (24%), Positives = 90/231 (38%), Gaps = 37/231 (16%)

Query: 156 SHVRGSRRPGSPRS---ASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARG 212
           S+   +R PGSP S   A  G       +  G PR      L      P+       A  
Sbjct: 37  SNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEP-----GAAS 91

Query: 213 PGRRLALHLQVPEGARQLGP---RTGAQPSRHRRQRAPGLALVVTGVSRIR-------PA 262
           P R+  LHL+ P+   +  P   R   +PS    + +    ++ + +++ +       P 
Sbjct: 92  PQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQ 151

Query: 263 HGAPGLPRAPKPSAGRG--GKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAG 320
           H  P +P +P+P  G+   G E  +   E+  R  GSPR  +H  S P PA    +   G
Sbjct: 152 HQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPR-GQHEPSKPPPAGETVTGGFG 210

Query: 321 PATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRL 371
                A   +G+SS+             A  +  +   P I +  P SGR+
Sbjct: 211 -----AKKRKGSSSQA-----------PASKKLNKEELPVIPKGKPKSGRV 245


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 89/332 (26%), Positives = 117/332 (35%), Gaps = 40/332 (12%)

Query: 6   ACSRDLRLAAGAGQAWGSAG-RGRRG----PAPRGQTGTQGVGSGGGGAGVRPEPCAGQR 60
           +C    + A G  Q  G  G RG  G    P  RG+ G QG+    G  G    P A   
Sbjct: 234 SCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA--- 290

Query: 61  PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAP--PPG--GRQLLLLRPPR 116
             G   +RGE   Q  +G     G     + G   +   A P  PPG  G   L    PR
Sbjct: 291 -PGFPGVRGEKGDQGEKGELGLPG-----LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPR 344

Query: 117 WVPSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSA-SPGV- 174
                 P  +  D         + RP     P      P         G+P +A +PG  
Sbjct: 345 MPGEQGPKGEKGDPGLPGEPGLQGRPGEL-GPQGPTGPPGAKGQEGAHGAPGAAGNPGAP 403

Query: 175 GRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQL-GPR 233
           G   A   +G P    A  LR T      R   G+A   G    +  +   GA  L GP 
Sbjct: 404 GHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPP 463

Query: 234 TGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAP----KPSAGRGGKEG-----G 284
              +      + +PGL     G    +   GAPG+P +P     P  G  G  G     G
Sbjct: 464 GKGKDGEPGLRGSPGLP----GPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 519

Query: 285 ERGTEMLRRLRGSPRPNRHPRSGPVPAHGVAS 316
           ++G+   R L G P P      GP    G++S
Sbjct: 520 DKGSPGSRGLPGFPGP-----QGPAGRDGLSS 546



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 81/319 (25%), Positives = 105/319 (32%), Gaps = 49/319 (15%)

Query: 31  PAPRGQTGTQGVGSGGGGAGV-----RPEPCAGQRPAGGKALRGEGQAQAAQGYAAANGW 85
           P  +GQ G  G     G  G       P P       G   LRG       +G   A G 
Sbjct: 382 PGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAG- 440

Query: 86  GTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRRPTHF 145
                          +P P G        PR  P   P         +D +P  R     
Sbjct: 441 ------------EEGSPGPVG--------PRGDPGA-PGLPGPPGKGKDGEPGLRGSPGL 479

Query: 146 YHPDEHKAQPSHVRGSRR-PGSPRS-ASPGVGRSWASSWAGVPRQPLALDLR-----PTW 198
             P   K      RG+   PGSP S   PG+G +     +G P    +   R     P  
Sbjct: 480 PGPLGTKGD----RGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 535

Query: 199 KAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSR 258
           + P  R  L S   PG    L   V        P     P     +  PG      G   
Sbjct: 536 QGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP-GREGTEG 594

Query: 259 IRPAHGAPGLP-----RAPKPSAGRGGKEG--GERGTEMLRRLRGSPRPNRHPRSGPVPA 311
            +   G PGLP       P+ S G  G +G  G++G +    + G   P  +P  GP  A
Sbjct: 595 KKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP--GPPGA 652

Query: 312 HGVASAAAGPATLRAPPGR 330
            G+A  AAGP  ++  PG+
Sbjct: 653 DGIA-GAAGPPGIQGSPGK 670



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 80/341 (23%), Positives = 105/341 (30%), Gaps = 70/341 (20%)

Query: 26  RGRRG-PAPRGQTGTQGVGSGGGGAGVRPEP--CAGQRPAGGKALRGEGQAQAAQGYAAA 82
           +G +G P   G+ GT+G     G  G+   P     Q   G +   GE   +  QG+   
Sbjct: 578 KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGV 637

Query: 83  NGWGTVLVSGLVPQDPRAAP-PPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRR 141
            G+            P   P PPG   +     P       P  Q +        P K  
Sbjct: 638 PGF----------MGPPGNPGPPGADGIAGAAGP-------PGIQGS--------PGKEG 672

Query: 142 PTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLR--PTWK 199
           P     P      P       R G P       G       AG P  P     R  P +K
Sbjct: 673 PPGPQGPSGLPGIPGEEGKEGRDGKP-------GPPGEPGKAGEPGLPGPEGARGPPGFK 725

Query: 200 APDARLALGSARGPGRRLALHLQ--VPEGARQLGPRTGAQ--------PSRHRRQRAPGL 249
                      RG    + L  Q  +P      GP TG Q        P ++    +PG 
Sbjct: 726 GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGP-TGPQGPQGPRGPPGKNGSPGSPGE 784

Query: 250 A--LVVTGVSRIRPAHGAPGLP-----RAPKPSAGRGG---KEG-----------GERGT 288
                  G    +  +G+PGLP     R P    G  G   KEG           GERG 
Sbjct: 785 PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD 844

Query: 289 EMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPG 329
             ++  +G P     P    +P H   +   GP  L    G
Sbjct: 845 PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENG 885


>gi|239747641 PREDICTED: hypothetical protein XP_002347916 [Homo
           sapiens]
          Length = 193

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/158 (30%), Positives = 56/158 (35%), Gaps = 37/158 (23%)

Query: 219 LHLQVP----EGARQLGPRTGAQPSRHRRQ------RAPGLALVVTGVSRIRPAHGAPGL 268
           L LQVP    EG   L  +   +P + +RQ      R+P  A     V  +R     P  
Sbjct: 35  LQLQVPLSGAEGKELLAAQAAHRPRQQQRQQQRPRPRSPDPAARGQHVPELRSRKPGPAA 94

Query: 269 ---------------PRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHG 313
                          P  P P     G  GGER  E     R  PRP   PR  P+ A G
Sbjct: 95  RTEEGGDVTGRPWQPPLLPPPGVPTPGNRGGERRGER----RAPPRPAGAPRGSPMAARG 150

Query: 314 VASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPP 351
            A   A P  L    G GA      P     S+R APP
Sbjct: 151 RARGEAEPPAL----GAGACDSRNQP----DSQRTAPP 180


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 69/266 (25%), Positives = 86/266 (32%), Gaps = 48/266 (18%)

Query: 94   VPQDPRAAPPPGGRQLL-------LLRPPRWVPSCFPNSQSADISQED------RKPAKR 140
            +P  P A PPP     L       L  PP   P   P S SA +          + P   
Sbjct: 776  LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835

Query: 141  RPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKA 200
                   P    A P+ ++  RRP +P   +   G     + A  P  P +     T   
Sbjct: 836  AAPLLQVPPSPPASPT-LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 894

Query: 201  PDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQ-----PSRHRRQRAPGLALVVTG 255
            PD      SA      L  +   PEG     P   A+     P+   R  AP LA     
Sbjct: 895  PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF---- 950

Query: 256  VSRIRPAHGAPGLPRAPKPSAGRGGKEG-----GERGTEMLRRLRGSPRPNRHPRSGPVP 310
                    GAPG P    P+ G G  +G        G E      G+  P      GP P
Sbjct: 951  -------RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP------GPSP 997

Query: 311  AHGVASAAAGPATLRAPPGRGASSET 336
                  AAAG        G GASS +
Sbjct: 998  GTSGGKAAAG-------AGAGASSRS 1016



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 77/270 (28%), Positives = 99/270 (36%), Gaps = 46/270 (17%)

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPG 214
           P+  RG R P + ++ SPG   S   + +G  R P  L  +    + +  +A G A    
Sbjct: 95  PASGRGERAPPA-KNTSPGPVSSPGRA-SGTTR-PGPLGQKGLRISAEETVARGKATEAP 151

Query: 215 RRLALHLQVPEGARQ--LGPRTGA-QPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRA 271
           +R AL      GAR+   GP  G   P+  RR RA G     T V   RPA  A   P  
Sbjct: 152 KRSALSA----GARRDTSGPTPGTPSPAMARRSRAAG-----TEVGLPRPAPSARPRPPT 202

Query: 272 -----------------PKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHP-RSGP----- 308
                            P P+A R    GG       R L  S  P   P RSGP     
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262

Query: 309 --VPAHGVASAAAGPATLRAP---PGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIAR 363
              PAH       G   LR P   P R  ++  + P   LSS   A P    T+A  +  
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSSPLATPSPSGTKARPVPP 319

Query: 364 SLPGSGRLQGLIFPSTGKNVQRHKSPPLPS 393
               +  L   + PS         +PP PS
Sbjct: 320 PDNAATPLPATLPPSPPLATPLPLAPPSPS 349



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 48/165 (29%), Positives = 64/165 (38%), Gaps = 30/165 (18%)

Query: 245 RAPGLALVVTGVSRIRPAHGAPGLPRAPKPSA-------GRGGKEGGERGTEMLRRLRGS 297
           RAPGL          RP    PG PR P P         G  G  G +   E    + G+
Sbjct: 20  RAPGLLTP-------RP----PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68

Query: 298 PRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTR 357
             P   PR+GP  + G +S    PA+     GRG   E   P +N S    + P R    
Sbjct: 69  TIPESAPRAGPTRSAGTSS--RNPASRPPASGRG---ERAPPAKNTSPGPVSSPGR---- 119

Query: 358 APSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402
             +   + PG    +GL   S  + V R K+   P   +LS  +R
Sbjct: 120 --ASGTTRPGPLGQKGLRI-SAEETVARGKATEAPKRSALSAGAR 161



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 88/400 (22%), Positives = 139/400 (34%), Gaps = 47/400 (11%)

Query: 13  LAAGAGQAWGSAGRGRRGPAPRGQTGTQG----VGSGGGGAGVRPEPCAGQRP-AGGKAL 67
           +A  +  A    G  R  P+ R +  T+G    V S    +   P P A +RP AGG   
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235

Query: 68  RGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVP------SC 121
           R   ++ ++     ++   +   +   P+ P     P  + L  LRPP+  P        
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295

Query: 122 FPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASS 181
                S+ ++       K RP     P ++ A P     +  P SP  A+P         
Sbjct: 296 LGPLSSSPLATPSPSGTKARPV---PPPDNAATP---LPATLPPSPPLATP--------- 340

Query: 182 WAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRH 241
              +P  P +    P+ +   +  A   ++ P       +Q P   + + P         
Sbjct: 341 ---LPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397

Query: 242 RRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPN 301
              +AP   L ++ + +   + G+P L       A         R T+    L    RP 
Sbjct: 398 PSLQAPPSPLALSSL-QATTSLGSPTL------QATHSFLTMSPRQTQ--ASLTSPSRPA 448

Query: 302 RHPRSGPVPAHGVASAAAGP--ATLRAPPGRGASSE-TMWPTENLSSRRRAPPQRRRTRA 358
             P   P P     S  A P   T  +P     SS  T+ P + LSS     PQ     A
Sbjct: 449 STPPDSP-PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ-----A 502

Query: 359 PSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLS 398
           P  +  +P       L  PS         +PPL +  SL+
Sbjct: 503 PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 75/308 (24%), Positives = 94/308 (30%), Gaps = 58/308 (18%)

Query: 95  PQDPRAAPPPGGRQLLLLRPPRWVPS---------------CFPNSQSADISQEDRKPAK 139
           P  P A PPP     L L P +  PS                 PN+ +  + Q    P  
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669

Query: 140 RRPTH--FYHPDEHKAQPSHVRGSRRPGS----PRSASPGVGRSWASSWAGVP------- 186
             P    F  P      PS    S+ P S    P    P    S   S +  P       
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729

Query: 187 --RQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQ 244
               PL +   P    P +  A    R P    A  LQVP       P +   P      
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS---PLAKPPP 786

Query: 245 RAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHP 304
           +AP             PA   P L   P P A   G+            L  SP     P
Sbjct: 787 QAP-------------PALATPPLQALPSPPASFPGQAPFSPSAS----LPMSPLATPPP 829

Query: 305 RSGPVPAHGVASAAAGP---ATLRA---PPGRGASSETMWPTENLSSRRRAPPQRRRTRA 358
           ++ PV A  +      P    TL+A   PP  G  +    P   L+     PP    +R+
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP--PSRS 887

Query: 359 PSIARSLP 366
           PS   S P
Sbjct: 888 PSSTLSGP 895


>gi|169211844 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 193

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 51/165 (30%), Positives = 64/165 (38%), Gaps = 24/165 (14%)

Query: 25  GRGRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANG 84
           G G   P P G    +G  +GGGG G+     + QR AG  A R  G A +        G
Sbjct: 20  GDGDEAPGPGGG---EGAAAGGGGGGLGSGGRSAQRRAGAGARRPIGAAPSVGPGGELQG 76

Query: 85  WGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSC---FPNSQSADISQEDRKP---- 137
           WG    SG  P  P      GGR+L    PPR   +     P +Q+A   +  R P    
Sbjct: 77  WGR--KSGCRPPGPEGW--AGGRKLRRWLPPRRFSNFCCRSPCAQTAVRRRRRRAPSPRG 132

Query: 138 --------AKRRPTHFYHPDEHKAQPSHV--RGSRRPGSPRSASP 172
                   A R         E  A+P H+  RG RR  + RS  P
Sbjct: 133 AGWREGAGAGRGTPATMAGGEWAAEPLHLPQRGRRRRFTCRSGRP 177


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 82/321 (25%), Positives = 107/321 (33%), Gaps = 44/321 (13%)

Query: 26  RGRRGPAPRGQTGTQGVGS-GGGGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANG 84
           RG+  P+PR    +QG G    GGAG R      +R    +  R    A   +G      
Sbjct: 359 RGKESPSPRSAPSSQGRGGRAAGGAGRR-----RRRRRRRRRSRSSASAPRRRG------ 407

Query: 85  WGTVLVSGLVPQDPRAAPPPG-GRQLLLLRPP------RWVPSCFPNSQSADISQEDRKP 137
                      + PR APP G  R L   R        R  P   P   S        K 
Sbjct: 408 ----------RRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKR 457

Query: 138 AKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGV-GRSWASSWAGVPRQPLALDLRP 196
           AK RP          +  +H R     G   S SPG   RSW+SS +    +  + + RP
Sbjct: 458 AKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRP 517

Query: 197 --TWKAPDARLALGSAR-GPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVV 253
               ++P  +  L   + G GR  A H +  E  R         P R RR+ +P      
Sbjct: 518 HSPSRSPSPKKPLSRDKDGEGR--ARHSEA-EATRARRRSRSYSPIRKRRRDSPSF---- 570

Query: 254 TGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHG 313
               RI  A   P     P PS+               R    SP P     S    +HG
Sbjct: 571 MEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSR----SPSPGHSHGSYSSRSHG 626

Query: 314 VASAAAGPATLRAPPGRGASS 334
             S    P+   +P     SS
Sbjct: 627 TRSRTRSPSRTPSPSYHSRSS 647



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 67/286 (23%), Positives = 92/286 (32%), Gaps = 42/286 (14%)

Query: 137 PAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRP 196
           P +R   H        +  SH   SR P          GR   S  +   R P       
Sbjct: 248 PGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSP------- 300

Query: 197 TWKAPDARLALGSAR---GPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVV 253
              +P      GS +   G G+R   H   P G+    P   + PS   R +A   A   
Sbjct: 301 ---SPSGGSGWGSPQRNGGSGQRSGAHGGRP-GSAHSPPDKPSSPSPRVRDKAAAAAPTP 356

Query: 254 TGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGS---------------- 297
               +  P+      PR+   S GRGG+  G  G    RR R                  
Sbjct: 357 PARGKESPS------PRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRR 410

Query: 298 PRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTR 357
           PRP     S    +   +S+ +G       PG    SE         ++ R P  R  + 
Sbjct: 411 PRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAST 470

Query: 358 APSIARSLPGS-GRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402
           +PS     PG+ GR  G    S+ ++   H      S      RSR
Sbjct: 471 SPS-----PGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSR 511



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 67/265 (25%), Positives = 89/265 (33%), Gaps = 45/265 (16%)

Query: 125 SQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAG 184
           S+S+   ++++   K+RP        H   P   R S R  S  S SP +   ++ S   
Sbjct: 226 SRSSKCKRKEKNKEKKRP--------HTESPG--RRSHRHSSGSSHSPSLSSHYSDS--- 272

Query: 185 VPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQ 244
             R P  L  +               R  GR+     Q   G+R   P  G+     +R 
Sbjct: 273 --RSPSRLSPKH--------------RDEGRKTGS--QRSSGSRSPSPSGGSGWGSPQRN 314

Query: 245 RAPGLALVVTGVSRIRPAHGAPGLPRAPKP----SAGRGGKEGGERGTEMLRRLRGSPRP 300
              G      G  R   AH  P  P +P P     A         RG E       SP P
Sbjct: 315 GGSGQRSGAHG-GRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKE-------SPSP 366

Query: 301 NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS 360
              P S      G A+  AG    R    R + S    P      R R  P R  +R+ S
Sbjct: 367 RSAPSSQG--RGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLS 424

Query: 361 IARSLPGSGRLQGLIFPSTGKNVQR 385
            ARS   SG  +G   P      +R
Sbjct: 425 RARSSSDSGSGRGAPGPGPEPGSER 449


>gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I
            subunit isoform b [Homo sapiens]
          Length = 2188

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 65/271 (23%), Positives = 92/271 (33%), Gaps = 49/271 (18%)

Query: 117  WVPSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGR 176
            W+      +  +  S +   P    P  F+HP    +Q    +G+     P+ A  G   
Sbjct: 1901 WLKHDSSQAPPSPFSPDASSPLLPMPAEFFHPAVSASQKGPEKGTGTGTLPKIALQG--- 1957

Query: 177  SWASSWAGVPR-----------QPLALDLRPTWKAPDARLALGS----ARGPGRRLALHL 221
            SWAS  +  PR              +LD  P+  A   +  L      +  P R L    
Sbjct: 1958 SWASLRS--PRVNCTLLRQATGSDTSLDASPSSSAGSLQTTLEDSLTLSDSPRRALGPPA 2015

Query: 222  QVPEGARQLGPRTGAQPSRHRRQRAPGLALV-VTGVSRIRPAHGAPGLPRA--------- 271
              P      GPR G  P+  RR    G  L  + G+   + +H + G             
Sbjct: 2016 PAP------GPRAGLSPAARRRLSLRGRGLFSLRGLRAHQRSHSSGGSTSPGCTHHDSMD 2069

Query: 272  PKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLR-APPGR 330
            P    GRGG  GG  G+E    L      +      P PA G+  A    +T   A PGR
Sbjct: 2070 PSDEEGRGGAGGGGAGSEHSETLSSLSLTSLFCPPPPPPAPGLTPARKFSSTSSLAAPGR 2129

Query: 331  --------GASSETMWPTENLSSRRRAPPQR 353
                    G +    W  +    R + PP R
Sbjct: 2130 PHAAALAHGLARSPSWAAD----RSKDPPGR 2156


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,130,970
Number of Sequences: 37866
Number of extensions: 1487607
Number of successful extensions: 11154
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 992
Number of HSP's that attempted gapping in prelim test: 7930
Number of HSP's gapped (non-prelim): 3523
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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