Guide to the Human Genome
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Search of human proteins with 169163540

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens]
         (195 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens]          422   e-119
gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens]          419   e-118
gi|4507425 teratocarcinoma-derived growth factor 1 [Homo sapiens]     261   2e-70
gi|14211837 cryptic [Homo sapiens]                                     76   2e-14
gi|118600995 cripto, FRL-1, cryptic family 1B [Homo sapiens]           76   2e-14
gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens]          44   9e-05
gi|148833508 notch1 preproprotein [Homo sapiens]                       40   0.001
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]                40   0.001
gi|134244285 Notch homolog 3 [Homo sapiens]                            40   0.002
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]               40   0.002
gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens]            40   0.002
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]                39   0.002
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]    39   0.004
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s...    38   0.005
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]    37   0.008
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]    37   0.008
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             37   0.011
gi|24430141 fibrillin 1 precursor [Homo sapiens]                       36   0.018
gi|24041035 notch 2 preproprotein [Homo sapiens]                       36   0.018
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti...    36   0.018
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]            36   0.018
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]               36   0.018
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]               36   0.018
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]     36   0.018
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]               36   0.018
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]       36   0.018
gi|41327708 crumbs homolog 1 precursor [Homo sapiens]                  36   0.018
gi|55770876 notch4 preproprotein [Homo sapiens]                        35   0.031
gi|148886654 polydom [Homo sapiens]                                    35   0.031
gi|20127446 integrin, beta 5 [Homo sapiens]                            35   0.040

>gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens]
          Length = 195

 Score =  422 bits (1085), Expect = e-119
 Identities = 195/195 (100%), Positives = 195/195 (100%)

Query: 1   MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE 60
           MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE
Sbjct: 1   MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE 60

Query: 61  GDLAFRDDSIQPQEEPAIRPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF 120
           GDLAFRDDSIQPQEEPAIRPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF
Sbjct: 61  GDLAFRDDSIQPQEEPAIRPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF 120

Query: 121 YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP 180
           YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP
Sbjct: 121 YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP 180

Query: 181 RTPELPPSACTTFIC 195
           RTPELPPSACTTFIC
Sbjct: 181 RTPELPPSACTTFIC 195


>gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens]
          Length = 195

 Score =  419 bits (1077), Expect = e-118
 Identities = 194/195 (99%), Positives = 194/195 (99%)

Query: 1   MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE 60
           MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE
Sbjct: 1   MGFVALETAKQQRDAGAHAQVAPRGPGAQSWEVWLRGRLVATRGSGARGASVLEVSRVKE 60

Query: 61  GDLAFRDDSIQPQEEPAIRPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF 120
           GDLAFRDDSIQPQEEPAI PRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF
Sbjct: 61  GDLAFRDDSIQPQEEPAICPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSF 120

Query: 121 YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP 180
           YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP
Sbjct: 121 YGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAP 180

Query: 181 RTPELPPSACTTFIC 195
           RTPELPPSACTTFIC
Sbjct: 181 RTPELPPSACTTFIC 195


>gi|4507425 teratocarcinoma-derived growth factor 1 [Homo sapiens]
          Length = 188

 Score =  261 bits (668), Expect = 2e-70
 Identities = 121/139 (87%), Positives = 124/139 (89%)

Query: 54  EVSRVKEGDLAFRDDSIQPQEEPAIRPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSF 113
           E +R   G LAFRDDSI PQEEPAIRPRSSQ VPPMGIQ SKE NRTCCLNGGTCMLGSF
Sbjct: 35  EFARPSRGYLAFRDDSIWPQEEPAIRPRSSQRVPPMGIQHSKELNRTCCLNGGTCMLGSF 94

Query: 114 CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVM 173
           CAC PSFYG NCEH VRKENCGSVPHDT LPKKCS+CKCWHGQLRCFPQAFLPGCDGLVM
Sbjct: 95  CACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVM 154

Query: 174 DEHLMAPRTPELPPSACTT 192
           DEHL+A RTPELPPSA TT
Sbjct: 155 DEHLVASRTPELPPSARTT 173


>gi|14211837 cryptic [Homo sapiens]
          Length = 223

 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 31/69 (44%), Positives = 38/69 (55%)

Query: 101 CCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCF 160
           CC NGGTC+LGSFC C   F G  CEH  R+  CG++ H     + C +C+C  G L C 
Sbjct: 90  CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149

Query: 161 PQAFLPGCD 169
           P      CD
Sbjct: 150 PLQTPDRCD 158


>gi|118600995 cripto, FRL-1, cryptic family 1B [Homo sapiens]
          Length = 223

 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 31/69 (44%), Positives = 38/69 (55%)

Query: 101 CCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCF 160
           CC NGGTC+LGSFC C   F G  CEH  R+  CG++ H     + C +C+C  G L C 
Sbjct: 90  CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149

Query: 161 PQAFLPGCD 169
           P      CD
Sbjct: 150 PLQTPDRCD 158


>gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens]
          Length = 379

 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 31/98 (31%), Positives = 36/98 (36%), Gaps = 32/98 (32%)

Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEH-----------------------GVRKENC--GS 136
           C+NGG C+   FC C P FYG NC+                        G+  E C    
Sbjct: 218 CMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISK 277

Query: 137 VPHDTRLPKKC---SMCKC---WHGQLRCFPQAFLPGC 168
            P   R   KC   S CKC   + G L C      PGC
Sbjct: 278 CPQPCRNGGKCIGKSKCKCSKGYQGDL-CSKPVCEPGC 314



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 3/56 (5%)

Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDT-RLPKKCSMCKCWHGQ 156
           C NGG C+  S C C   + G  C   V +  CG+  H T   P KC   + WHG+
Sbjct: 282 CRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGA--HGTCHEPNKCQCQEGWHGR 335



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 12/33 (36%), Positives = 15/33 (45%)

Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC 134
           C NGG C     C C   F+G +CE  +    C
Sbjct: 186 CRNGGFCNERRICECPDGFHGPHCEKALCTPRC 218


>gi|148833508 notch1 preproprotein [Homo sapiens]
          Length = 2555

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 15/80 (18%)

Query: 102  CLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSM--------C 150
            C N GTC+  +G + C C P F G  CE  V +  C S P D R  + C          C
Sbjct: 1238 CFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNE--CLSNPCDARGTQNCVQRVNDFHCEC 1295

Query: 151  KCWHGQLRCFPQAFLPGCDG 170
            +  H   RC  ++ + GC G
Sbjct: 1296 RAGHTGRRC--ESVINGCKG 1313



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 29/77 (37%), Positives = 34/77 (44%), Gaps = 14/77 (18%)

Query: 102  CLNGGTCMLG--SF-CACLPSFYGWNCEHGVRKENCGSVP--HDTRLPKKCSMCKCWHGQ 156
            C NGGTC+ G  SF C C P F G  C+H V +  C S P  H       C   +C    
Sbjct: 992  CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNE--CDSQPCLHGGTCQDGCGSYRC---- 1045

Query: 157  LRCFPQAFL-PGCDGLV 172
                PQ +  P C  LV
Sbjct: 1046 --TCPQGYTGPNCQNLV 1060



 Score = 36.6 bits (83), Expect = 0.014
 Identities = 24/61 (39%), Positives = 29/61 (47%), Gaps = 9/61 (14%)

Query: 93  DSKEPNRTCCLNGGTCMLG---SFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSM 149
           D   PN   C NGG+C  G   +FC CLP F G  CE  + +  C S P   R    C+ 
Sbjct: 909 DDCRPNP--CHNGGSCTDGINTAFCDCLPGFRGTFCEEDINE--CASDP--CRNGANCTD 962

Query: 150 C 150
           C
Sbjct: 963 C 963



 Score = 36.2 bits (82), Expect = 0.018
 Identities = 16/32 (50%), Positives = 18/32 (56%), Gaps = 4/32 (12%)

Query: 102 CLNGGTCM----LGSFCACLPSFYGWNCEHGV 129
           C NGGTC     +   CACLP F G NCE  +
Sbjct: 227 CQNGGTCRPTGDVTHECACLPGFTGQNCEENI 258



 Score = 34.3 bits (77), Expect = 0.069
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 7/56 (12%)

Query: 102 CLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP--HDTRLPKKCSMCKC 152
           C N  TC+  +G F C C+P + G +CE  V  + C S P  H+ R   K +  +C
Sbjct: 461 CQNDATCLDQIGEFQCICMPGYEGVHCE--VNTDECASSPCLHNGRCLDKINEFQC 514



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 8/65 (12%)

Query: 102 CLNGGTCM---LGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLR 158
           C NGG C+       C C PSF+G  C   V +  CG  P    L +    C    G  R
Sbjct: 149 CANGGQCLPFEASYICHCPPSFHGPTCRQDVNE--CGQKP---GLCRHGGTCHNEVGSYR 203

Query: 159 CFPQA 163
           C  +A
Sbjct: 204 CVCRA 208



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 14/72 (19%)

Query: 93   DSKEPNRTCCLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSM 149
            D  E +   CL+GGTC    GS+ C C   + G NC++ V    C S P         + 
Sbjct: 1021 DVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHW--CDSSPCK-------NG 1071

Query: 150  CKCW--HGQLRC 159
             KCW  H Q RC
Sbjct: 1072 GKCWQTHTQYRC 1083



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 9/60 (15%)

Query: 88   PMGIQDSKEPN--RTC----CLNGGTCMLG---SFCACLPSFYGWNCEHGVRKENCGSVP 138
            P G + +   N  RTC    CLNGGTC+ G     C CL  F G  C+        G  P
Sbjct: 1337 PAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNP 1396



 Score = 32.3 bits (72), Expect = 0.26
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 5/40 (12%)

Query: 102 CLNGGTCM---LGSFCACLPSFYGWNCEHGVRKENCGSVP 138
           C+NGGTC     G  C C   F G NC+  + +  C S P
Sbjct: 762 CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINE--CASNP 799



 Score = 32.3 bits (72), Expect = 0.26
 Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 8/42 (19%)

Query: 102  CLNGGTCMLGS------FCACLPSFYGWNCEHGVRKENCGSV 137
            C NGGTC + S       C C   F G  CE+  R   CGS+
Sbjct: 1316 CKNGGTCAVASNTARGFICKCPAGFEGATCENDAR--TCGSL 1355



 Score = 28.9 bits (63), Expect = 2.9
 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 5/40 (12%)

Query: 102  CLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
            C NG TC   LG + C C+  ++G NC   +  + C S P
Sbjct: 1154 CQNGATCTDYLGGYSCKCVAGYHGVNCSEEI--DECLSHP 1191


>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
          Length = 1541

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 29/81 (35%), Positives = 34/81 (41%), Gaps = 14/81 (17%)

Query: 102 CLNGGTC-MLGSFCACLPSFYGWNCEHGV----------RKENCGSVPHDTRLPKKCSMC 150
           C NGGTC  +   C C P   G NCE G           +K NC +     RL   C   
Sbjct: 570 CQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCD 629

Query: 151 KCWHGQ---LRCFPQAFLPGC 168
              +G+   L C P AF PGC
Sbjct: 630 PGLYGRFCHLTCPPWAFGPGC 650



 Score = 36.2 bits (82), Expect = 0.018
 Identities = 34/98 (34%), Positives = 45/98 (45%), Gaps = 16/98 (16%)

Query: 65  FRDDSIQPQEEPA-IRPRSSQLVPPMGIQDS--KEPNRTC--CLNGGTCMLG-SFCACLP 118
           F+DD +   EE A +R   +     + + DS   + + TC  C NGGTC+LG   C C  
Sbjct: 485 FQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPE 544

Query: 119 SFYGWNCEHGVRKENCGSVPHDTRLPKKCSM-CKCWHG 155
            + G  C      E C   P DT   K CS  C C +G
Sbjct: 545 GWTGLIC-----NETC---PPDT-FGKNCSFSCSCQNG 573



 Score = 33.9 bits (76), Expect = 0.090
 Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 15/88 (17%)

Query: 99   RTCCLNGGTCM-LGSFCACLPSFYGWNCEH----GVRKENC-------GSVPHDTRLPKK 146
            R  C  G  C  +   C C P F G  CE     G   E+C       G  P        
Sbjct: 1131 RCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGT 1190

Query: 147  CSMCKCWHG---QLRCFPQAFLPGCDGL 171
            CS    +HG   Q RC P  + PGC+ L
Sbjct: 1191 CSCAAGYHGPSCQQRCPPGRYGPGCEQL 1218



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 6/67 (8%)

Query: 94  SKEPNRTCCLNGGTCMLGSF--CACLPSFYGWNCEHGV---RKENCGSVPHDTRLPKKCS 148
           S E + + C +GG C+ GS   C C P F G  C++ V   R  N G        P    
Sbjct: 125 SAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGS-Y 183

Query: 149 MCKCWHG 155
           +C+C  G
Sbjct: 184 LCECKPG 190



 Score = 32.3 bits (72), Expect = 0.26
 Identities = 31/111 (27%), Positives = 42/111 (37%), Gaps = 21/111 (18%)

Query: 84  QLVPPMGIQDSKEPNRTCCLNGGTCMLGS-FCACLPSFYGWNCEHGVRKENCGSVPHDTR 142
           Q V P G        R  C N G C   +  C+C P + G++C+   R  + G    D  
Sbjct: 814 QDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQ---RACDTGHWGPDCS 870

Query: 143 LPKKCS-----------MCKCWHGQL--RCFPQA----FLPGCDGLVMDEH 176
            P  CS           +C C  G +  RC  Q     F PGC+     +H
Sbjct: 871 HPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQH 921



 Score = 32.3 bits (72), Expect = 0.26
 Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 14/102 (13%)

Query: 81   RSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGS-FCACLPSFYGWNCEH----GVRKENCG 135
            R  +L  P G   +       C N  TC   +  C C P FYG  CEH    G     C 
Sbjct: 1329 RHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQ 1388

Query: 136  SV---PHDTRLPKKCSMCKC---WHG---QLRCFPQAFLPGC 168
             +    H          C C   +HG   +  C P +F  GC
Sbjct: 1389 GLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGC 1430



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 22/84 (26%), Positives = 31/84 (36%), Gaps = 20/84 (23%)

Query: 102  CLNGGTC------------MLGSFC--ACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKC 147
            C NG +C             +G  C  AC    YG NC H    +N G+      +   C
Sbjct: 1005 CFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC---DPVSGHC 1061

Query: 148  SMCKCWHG---QLRCFPQAFLPGC 168
            +  + W G   +  C P+    GC
Sbjct: 1062 ACPEGWAGLACEKECLPRDVRAGC 1085



 Score = 28.5 bits (62), Expect = 3.8
 Identities = 21/68 (30%), Positives = 25/68 (36%), Gaps = 8/68 (11%)

Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG-SVPHDTRLPKKCSMCKCW------- 153
           C    TC +G  C  +    G  C  G + E+CG   P  T      S C C        
Sbjct: 695 CWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGV 754

Query: 154 HGQLRCFP 161
            GQ RC P
Sbjct: 755 TGQCRCPP 762



 Score = 28.5 bits (62), Expect = 3.8
 Identities = 14/40 (35%), Positives = 18/40 (45%), Gaps = 1/40 (2%)

Query: 88   PMGIQDSKEPNRTCCLNGGTC-MLGSFCACLPSFYGWNCE 126
            P G+      +   C NGGTC  +   CAC   + G  CE
Sbjct: 1034 PAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACE 1073


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 32/102 (31%), Positives = 42/102 (41%), Gaps = 19/102 (18%)

Query: 92  QDSKEPNRTCCLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCS 148
           QD  + +   CLNGG+C   +GSF C+CLP F G  C   V          D  L   C 
Sbjct: 848 QDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDV----------DECLSNPCG 897

Query: 149 MCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAPRTPELPPSAC 190
              C    +  F     PG  G   ++ L     P+  PS+C
Sbjct: 898 PGTC-TDHVASFTCTCPPGYGGFHCEQDL-----PDCSPSSC 933



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 5/40 (12%)

Query: 102  CLNGGTC---MLGSFCACLPSFYGWNCEHGVRKENCGSVP 138
            C +GGTC   M G  C CLP + G NCE  V  + C S P
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDV--DECASQP 1130



 Score = 37.0 bits (84), Expect = 0.011
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 16/74 (21%)

Query: 92  QDSKEPNRTCCLNGGTCMLG--SF-CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKC- 147
           QD  + + + C NGGTC+ G  SF C C P + G +C+H            D  L + C 
Sbjct: 923 QDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEA----------DPCLSRPCL 972

Query: 148 --SMCKCWHGQLRC 159
              +C   H   RC
Sbjct: 973 HGGVCSAAHPGFRC 986



 Score = 36.2 bits (82), Expect = 0.018
 Identities = 18/32 (56%), Positives = 18/32 (56%), Gaps = 4/32 (12%)

Query: 102 CLNGGTCM----LGSFCACLPSFYGWNCEHGV 129
           C NGGTC     L   CACLP F G NCE  V
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNV 237



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 3/38 (7%)

Query: 102  CLNGGTC--MLGSF-CACLPSFYGWNCEHGVRKENCGS 136
            CL+ GTC  ++G F C C P + G  CE  + +   G+
Sbjct: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGA 1213



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 10/64 (15%)

Query: 102  CLNGGTCML---GSFCACLPSFYGWNCEHGVRKENCGSVP--HDTRLPKKCSMCKC---W 153
            CL+GG C     G  C CL SF G  C+  V  + C   P  +  R  +  + C C   W
Sbjct: 971  CLHGGVCSAAHPGFRCTCLESFTGPQCQTLV--DWCSRQPCQNGGRCVQTGAYCLCPPGW 1028

Query: 154  HGQL 157
             G+L
Sbjct: 1029 SGRL 1032



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 26/72 (36%), Positives = 29/72 (40%), Gaps = 21/72 (29%)

Query: 102 CLNGGTCM---LGSFCACLPSFYGWN-----------CEHGVRKENCGSVPHDTRLPKKC 147
           C  GGTC    +G  C C P   G             CEHG R   C S P   +LP  C
Sbjct: 743 CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGR---CESAP--GQLP-VC 796

Query: 148 SMCKCWHGQLRC 159
           S  + W G  RC
Sbjct: 797 SCPQGWQGP-RC 807



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 12/30 (40%), Positives = 18/30 (60%), Gaps = 1/30 (3%)

Query: 98   NRTCCLNGGTCM-LGSFCACLPSFYGWNCE 126
            +R  C NGG C+  G++C C P + G  C+
Sbjct: 1005 SRQPCQNGGRCVQTGAYCLCPPGWSGRLCD 1034



 Score = 28.1 bits (61), Expect = 4.9
 Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 3/31 (9%)

Query: 102 CLNGGTCMLG---SFCACLPSFYGWNCEHGV 129
           CLNGGTC+ G     C C P + G  C   V
Sbjct: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDV 275


>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
          Length = 1044

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 16/84 (19%)

Query: 98  NRTCCLNGGTCM-LGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSM-CKCWHG 155
           NR  C NG  C  +   C C   F GW CE     E C    H     K C + C+C HG
Sbjct: 144 NRCQCQNGALCNPITGACVCAAGFRGWRCE-----ELCAPGTHG----KGCQLPCQCRHG 194

Query: 156 QLRCFPQA----FLPGCDGLVMDE 175
              C P+A      PG  G+  +E
Sbjct: 195 -ASCDPRAGECLCAPGYTGVYCEE 217



 Score = 27.7 bits (60), Expect = 6.5
 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 11/57 (19%)

Query: 106 GTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCS-MCKCWHGQLRCFP 161
           G C+    C C P + G +C  G   ++ G  PH       CS  C+C +G L C P
Sbjct: 110 GRCVSPDTCHCEPGWGGPDCSSGCDSDHWG--PH-------CSNRCQCQNGAL-CNP 156



 Score = 27.7 bits (60), Expect = 6.5
 Identities = 12/31 (38%), Positives = 16/31 (51%), Gaps = 2/31 (6%)

Query: 98  NRTC-CLNGGTCM-LGSFCACLPSFYGWNCE 126
           N +C C NG  C  +   C+C P + G  CE
Sbjct: 490 NESCTCANGAACSPIDGSCSCTPGWLGDTCE 520


>gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens]
          Length = 4349

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 10/65 (15%)

Query: 98   NRTCCLNGGTCM----LGSFCACLPSFYGWNCEHGVRKENCGSVP----HDTRLPKKCSM 149
            ++  CLNGG C      G  C C P F G +CE G  +ENC   P        L  K + 
Sbjct: 3952 SQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQG--RENCTFAPCLEGGTCILSPKGAS 4009

Query: 150  CKCWH 154
            C C H
Sbjct: 4010 CNCPH 4014


>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
          Length = 3144

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 18/84 (21%)

Query: 96   EPNRTCCLNGGTCMLGS----FCACLPSFYGWNCEHGVRKENCGSVP--HDTRLPKKCS- 148
            E N   CLNGG C+ G      C CLP F G  CE  + +  C S P  H        + 
Sbjct: 1125 ELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININE--CSSSPCLHGADCEDHING 1182

Query: 149  -MCKC---WHG-----QLRCFPQA 163
             +CKC   W G     +L C P +
Sbjct: 1183 YVCKCQPGWSGHHCENELECIPNS 1206



 Score = 28.9 bits (63), Expect = 2.9
 Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 7/41 (17%)

Query: 94  SKEPNRTCCLNGGTCMLGS---FCACLPSFYGWNCEHGVRK 131
           S EP    C N GTC+  +   FC C P ++G  CE  V K
Sbjct: 933 SSEP----CKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNK 969



 Score = 27.3 bits (59), Expect = 8.4
 Identities = 12/31 (38%), Positives = 14/31 (45%), Gaps = 3/31 (9%)

Query: 102  CLNGGTCMLGSF---CACLPSFYGWNCEHGV 129
            C NGG C +      C CLP + G  C   V
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSV 2914


>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
          Length = 1590

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 78   IRPRSSQLVPPMGIQDSKEPN-RTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGS 136
            I+P   Q +P  G     E +    C +GGTC+ G+ C C   F G  CE  V   +C +
Sbjct: 1341 IKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCEN 1400

Query: 137  VPHDTRLPKKCSMCKCWHG 155
                   P  C     W+G
Sbjct: 1401 -GGQCLTPDICQCKPGWYG 1418



 Score = 35.8 bits (81), Expect = 0.024
 Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 13/100 (13%)

Query: 102  CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQL-RCF 160
            CLNGG+C   + C C   F+G +C++      C +  H  R     ++C C  G   R F
Sbjct: 1430 CLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMR----NNVCVCREGYTGRRF 1485

Query: 161  PQAFLPGCDGLVMD-EHLMAPRTPELPP----SACTTFIC 195
             ++    CD   M+    + P T   P       C T IC
Sbjct: 1486 QKSI---CDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPIC 1522



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 12/46 (26%)

Query: 102  CLNGGTCML------GS---FCACLPSFYGWNCE---HGVRKENCG 135
            CLNGG+C+       GS    C CLP F+G  CE    G +   CG
Sbjct: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCG 1228



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 23/105 (21%)

Query: 102  CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFP 161
            C N G C+  + C CLP   G  C+    +E+C         P       C  G L   P
Sbjct: 1334 CKNHGKCIKPNICQCLPGHGGATCD----EEHCN--------PPCQHGGTCLAGNLCTCP 1381

Query: 162  QAFL-PGCDGLVMDEH------LMAPRTPELPPS----ACTTFIC 195
              F+ P C+ +V + H       + P   +  P      C+T +C
Sbjct: 1382 YGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALC 1426



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 4/54 (7%)

Query: 102  CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHG 155
            C NGG C+    C C P +YG  C   +    C  V  +     K + C C +G
Sbjct: 1398 CENGGQCLTPDICQCKPGWYGPTCSTAL----CDPVCLNGGSCNKPNTCLCPNG 1447



 Score = 32.7 bits (73), Expect = 0.20
 Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 2/67 (2%)

Query: 102  CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFP 161
            C+NGG C+  S C+C   + G  C   +  + C +   +   P  C     W G +RC  
Sbjct: 1494 CMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKN-GGECIAPSICHCPSSWEG-VRCQI 1551

Query: 162  QAFLPGC 168
                P C
Sbjct: 1552 PICNPKC 1558



 Score = 32.0 bits (71), Expect = 0.34
 Identities = 16/67 (23%), Positives = 25/67 (37%), Gaps = 2/67 (2%)

Query: 102  CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFP 161
            C     C+  + C C P + G NC+  +   +C +  H   +      C   HG   C  
Sbjct: 1302 CGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKN--HGKCIKPNICQCLPGHGGATCDE 1359

Query: 162  QAFLPGC 168
            +   P C
Sbjct: 1360 EHCNPPC 1366



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 10/29 (34%), Positives = 16/29 (55%)

Query: 102  CLNGGTCMLGSFCACLPSFYGWNCEHGVR 130
            CL GG C+  + C+C   + G  CE  ++
Sbjct: 1558 CLYGGRCIFPNVCSCRTEYSGVKCEKKIQ 1586


>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
           sapiens]
          Length = 1037

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 10/66 (15%)

Query: 88  PMGIQDSKEPNRTCCLNGGTCML-GSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKK 146
           P G+      N   C NGGTC+     C C P F G +C+   +    G         K+
Sbjct: 568 PEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYG---------KR 618

Query: 147 CSMCKC 152
           C  CKC
Sbjct: 619 CVPCKC 624



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 16/66 (24%)

Query: 114 CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQL--------RCFPQAFL 165
           C+CLP + G +C      E+C   P DT  P     C C HG +        +C P    
Sbjct: 380 CSCLPGWAGLHC-----NESC---PQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTG 431

Query: 166 PGCDGL 171
           P C  L
Sbjct: 432 PHCASL 437



 Score = 27.7 bits (60), Expect = 6.5
 Identities = 20/85 (23%), Positives = 33/85 (38%), Gaps = 9/85 (10%)

Query: 106 GTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFL 165
           G C+  + C C+P + G +C        C       +  K CS   C +    C P++ +
Sbjct: 112 GRCVAPNQCQCVPGWRGDDC-----SSECAPGMWGPQCDKPCS---CGNNS-SCDPKSGV 162

Query: 166 PGCDGLVMDEHLMAPRTPELPPSAC 190
             C   +   + + P TP     AC
Sbjct: 163 CSCPSGLQPPNCLQPCTPGYYGPAC 187


>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
          Length = 814

 Score = 37.4 bits (85), Expect = 0.008
 Identities = 19/52 (36%), Positives = 21/52 (40%), Gaps = 1/52 (1%)

Query: 144 PKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAPRTPELPPSACTTFIC 195
           P  C+ C C  G   C PQA LP C G   +            P ACTT  C
Sbjct: 111 PDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYG-NGETFSPDACTTCRC 161



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 9/20 (45%), Positives = 12/20 (60%)

Query: 147 CSMCKCWHGQLRCFPQAFLP 166
           C +C CW G + C P+A  P
Sbjct: 743 CHLCLCWEGSVSCEPKACAP 762


>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
          Length = 1503

 Score = 37.4 bits (85), Expect = 0.008
 Identities = 19/52 (36%), Positives = 21/52 (40%), Gaps = 1/52 (1%)

Query: 144 PKKCSMCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAPRTPELPPSACTTFIC 195
           P  C+ C C  G   C PQA LP C G   +            P ACTT  C
Sbjct: 111 PDACTACVCQDGAAHCGPQAHLPHCRGCSQNGQTYG-NGETFSPDACTTCRC 161



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 9/20 (45%), Positives = 12/20 (60%)

Query: 147 CSMCKCWHGQLRCFPQAFLP 166
           C +C CW G + C P+A  P
Sbjct: 682 CHLCLCWEGSVSCEPKACAP 701



 Score = 28.9 bits (63), Expect = 2.9
 Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 17/81 (20%)

Query: 93  DSKEPNRTCCLNGGTCMLGSF------CA--------CLPSFYGWNCEHGVRKENCGSVP 138
           D +EP   C   GG    G        C+        C P+  G    HGV   +  ++P
Sbjct: 734 DPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGCRY-HGVTTASGETLP 792

Query: 139 HDTRLPKKCSMCKCWHGQLRC 159
               L   CS+C C  G +RC
Sbjct: 793 DP--LDPTCSLCTCQEGSMRC 811


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 37.0 bits (84), Expect = 0.011
 Identities = 16/30 (53%), Positives = 19/30 (63%), Gaps = 1/30 (3%)

Query: 99   RTCCLNGGTCMLGSFCACLPSFYGWNCEHG 128
            R  CL+GGTC  G+ C CLP F G  C+ G
Sbjct: 4150 REPCLHGGTCQ-GTRCLCLPGFSGPRCQQG 4178



 Score = 28.1 bits (61), Expect = 4.9
 Identities = 22/69 (31%), Positives = 25/69 (36%), Gaps = 11/69 (15%)

Query: 102  CLNGGTC----MLGSFCACLPSFYGWNCEHG----VRKENCGSVPHDTRLPK-KCSMCKC 152
            C NGG C         C C   F G  CEH        E CG        P  +   C+C
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRGYTCRC 3912

Query: 153  WHGQ--LRC 159
              G+  LRC
Sbjct: 3913 HLGRSGLRC 3921


>gi|24430141 fibrillin 1 precursor [Homo sapiens]
          Length = 2871

 Score = 36.2 bits (82), Expect = 0.018
 Identities = 16/36 (44%), Positives = 19/36 (52%)

Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSV 137
           CLNGG C+  + CAC   F G  CE   R   C +V
Sbjct: 154 CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTV 189


>gi|24041035 notch 2 preproprotein [Homo sapiens]
          Length = 2471

 Score = 36.2 bits (82), Expect = 0.018
 Identities = 31/122 (25%), Positives = 39/122 (31%), Gaps = 32/122 (26%)

Query: 102  CLNGGTCML------GSFCACLPSFYGWNCEHGVRKENCGS--------------VPHDT 141
            CLNGGTC +      G  C C P F G  C+    +  C                 P   
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPR 1372

Query: 142  RLPKKCSMCKCWHGQLRCFPQ--------AFLPGCDGLVMDEHLMAPRTPELPPSACTTF 193
                 C+   C HG   C PQ           P   G   + +   P T   PP+ C + 
Sbjct: 1373 DCESGCASSPCQHGG-SCHPQRQPPYYSCQCAPPFSGSRCELYTAPPST---PPATCLSQ 1428

Query: 194  IC 195
             C
Sbjct: 1429 YC 1430



 Score = 35.4 bits (80), Expect = 0.031
 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 3/33 (9%)

Query: 102  CLNGGTCM--LGSF-CACLPSFYGWNCEHGVRK 131
            CLNGG CM  +G + C CLP F G  CE  + +
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINE 1267



 Score = 34.7 bits (78), Expect = 0.053
 Identities = 16/32 (50%), Positives = 18/32 (56%), Gaps = 4/32 (12%)

Query: 102 CLNGGTC-MLGSF---CACLPSFYGWNCEHGV 129
           C+NGGTC   G F   C CLP F G  CE  +
Sbjct: 230 CVNGGTCRQTGDFTFECNCLPGFEGSTCERNI 261



 Score = 33.9 bits (76), Expect = 0.090
 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 5/49 (10%)

Query: 93  DSKEPNRTCCLNGGTC---MLGSFCACLPSFYGWNCEHGVRKENCGSVP 138
           D  E     C NGGTC   + G  C C   F G+NC+  V  + C S P
Sbjct: 757 DKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ--VNIDECASNP 803



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 13/79 (16%)

Query: 102 CLNGGTCMLGS---FCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLR 158
           C NGG+CM G     C CLP F G  C+  + +  C S P      K    C  +     
Sbjct: 920 CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNE--CLSEP-----CKNGGTCSDYVNSYT 972

Query: 159 CFPQAFLPGCDGLVMDEHL 177
           C  QA   G DG+  + ++
Sbjct: 973 CKCQA---GFDGVHCENNI 988



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 5/40 (12%)

Query: 102  CLNGGTC--MLGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
            C +G TC   +G + C C+P + G NCE+ V  + C + P
Sbjct: 1158 CQHGATCSDFIGGYRCECVPGYQGVNCEYEV--DECQNQP 1195



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 5/49 (10%)

Query: 93  DSKEPNRTCCLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
           D  E +   C N  TC+  +G F C C+P F G +CE  + +  C S P
Sbjct: 456 DINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINE--CQSNP 502



 Score = 30.4 bits (67), Expect = 1.00
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 5/46 (10%)

Query: 96   EPNRTCCLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
            E   + C NGGTC+  + SF C C   F G  C H + +  C S P
Sbjct: 990  ECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINE--CSSHP 1033



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 5/40 (12%)

Query: 102 CLNGGTCM---LGSFCACLPSFYGWNCEHGVRKENCGSVP 138
           CLN G C+    G  C C P   G NCE  +  ++C S P
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCE--INFDDCASNP 653



 Score = 28.1 bits (61), Expect = 4.9
 Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 7/60 (11%)

Query: 102 CLNGGTCMLGS----FCACLPSFYGWNCE--HGVRKENCGSVPHDTRLPKKCSMCKCWHG 155
           CLNGGTC + S     C C   F G  C+         C +    T +  + S CKC  G
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFS-CKCLTG 173



 Score = 28.1 bits (61), Expect = 4.9
 Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 3/31 (9%)

Query: 102 CLNGGTC--MLGSF-CACLPSFYGWNCEHGV 129
           C+N G C    GS+ C C P F G +CE  +
Sbjct: 882 CMNHGLCHNTQGSYMCECPPGFSGMDCEEDI 912



 Score = 27.3 bits (59), Expect = 8.4
 Identities = 14/33 (42%), Positives = 16/33 (48%), Gaps = 3/33 (9%)

Query: 102 CLNGGTC--MLGSF-CACLPSFYGWNCEHGVRK 131
           C NG TC  +   F C CL  F G  CE  V +
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 185


>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
           [Homo sapiens]
          Length = 909

 Score = 36.2 bits (82), Expect = 0.018
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 81  RSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG 135
           R++++   M  Q +       C NGGT   G  CACLP F G  C+   R +N G
Sbjct: 826 RTTRITSQMTTQSTLTTTAGTCDNGGTWEQGQ-CACLPGFSGDRCQLQTRCQNGG 879



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 1/37 (2%)

Query: 99  RTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG 135
           +T C NGG    G  C C  +FYG +CE  V + + G
Sbjct: 872 QTRCQNGGQWD-GLKCQCPSTFYGSSCEFAVEQVDLG 907


>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
          Length = 1486

 Score = 36.2 bits (82), Expect = 0.018
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 81   RSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG 135
            R++++   M  Q +       C NGGT   G  CACLP F G  C+   R +N G
Sbjct: 1100 RTTRITSQMTTQSTLTTTAGTCDNGGTWEQGQ-CACLPGFSGDRCQLQTRCQNGG 1153



 Score = 27.7 bits (60), Expect = 6.5
 Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)

Query: 99   RTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRK 131
            +T C NGG    G  C C  +FYG +CE  V +
Sbjct: 1146 QTRCQNGGQWD-GLKCQCPSTFYGSSCEFAVEQ 1177


>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
          Length = 839

 Score = 36.2 bits (82), Expect = 0.018
 Identities = 16/41 (39%), Positives = 23/41 (56%)

Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTR 142
           C NGG C+  + CAC   F G +CE  + + + G V  D+R
Sbjct: 552 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSR 592



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 14/78 (17%)

Query: 93  DSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC-------GSVPHDTRL-- 143
           +S E    C     +C   + C  L   Y   C HG   +NC       G V H+ ++  
Sbjct: 621 ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG---KNCTGDCIHDGKVKHNGQIWV 677

Query: 144 --PKKCSMCKCWHGQLRC 159
               +CS+C C +G + C
Sbjct: 678 LENDRCSVCSCQNGFVMC 695


>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
          Length = 815

 Score = 36.2 bits (82), Expect = 0.018
 Identities = 16/41 (39%), Positives = 23/41 (56%)

Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTR 142
           C NGG C+  + CAC   F G +CE  + + + G V  D+R
Sbjct: 528 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSR 568



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 14/78 (17%)

Query: 93  DSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC-------GSVPHDTRL-- 143
           +S E    C     +C   + C  L   Y   C HG   +NC       G V H+ ++  
Sbjct: 597 ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG---KNCTGDCIHDGKVKHNGQIWV 653

Query: 144 --PKKCSMCKCWHGQLRC 159
               +CS+C C +G + C
Sbjct: 654 LENDRCSVCSCQNGFVMC 671


>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
          Length = 816

 Score = 36.2 bits (82), Expect = 0.018
 Identities = 16/41 (39%), Positives = 23/41 (56%)

Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTR 142
           C NGG C+  + CAC   F G +CE  + + + G V  D+R
Sbjct: 529 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSR 569



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 14/78 (17%)

Query: 93  DSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC-------GSVPHDTRL-- 143
           +S E    C     +C   + C  L   Y   C HG   +NC       G V H+ ++  
Sbjct: 598 ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG---KNCTGDCIHDGKVKHNGQIWV 654

Query: 144 --PKKCSMCKCWHGQLRC 159
               +CS+C C +G + C
Sbjct: 655 LENDRCSVCSCQNGFVMC 672


>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
          Length = 866

 Score = 36.2 bits (82), Expect = 0.018
 Identities = 16/41 (39%), Positives = 23/41 (56%)

Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTR 142
           C NGG C+  + CAC   F G +CE  + + + G V  D+R
Sbjct: 579 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSR 619



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 14/78 (17%)

Query: 93  DSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC-------GSVPHDTRL-- 143
           +S E    C     +C   + C  L   Y   C HG   +NC       G V H+ ++  
Sbjct: 648 ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG---KNCTGDCIHDGKVKHNGQIWV 704

Query: 144 --PKKCSMCKCWHGQLRC 159
               +CS+C C +G + C
Sbjct: 705 LENDRCSVCSCQNGFVMC 722


>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
          Length = 816

 Score = 36.2 bits (82), Expect = 0.018
 Identities = 16/41 (39%), Positives = 23/41 (56%)

Query: 102 CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTR 142
           C NGG C+  + CAC   F G +CE  + + + G V  D+R
Sbjct: 529 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDSR 569



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 14/78 (17%)

Query: 93  DSKEPNRTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENC-------GSVPHDTRL-- 143
           +S E    C     +C   + C  L   Y   C HG   +NC       G V H+ ++  
Sbjct: 598 ESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHG---KNCTGDCIHDGKVKHNGQIWV 654

Query: 144 --PKKCSMCKCWHGQLRC 159
               +CS+C C +G + C
Sbjct: 655 LENDRCSVCSCQNGFVMC 672


>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
          Length = 1406

 Score = 36.2 bits (82), Expect = 0.018
 Identities = 19/40 (47%), Positives = 23/40 (57%), Gaps = 5/40 (12%)

Query: 102 CLNGGTCM--LGS-FCACLPSFYGWNCEHGVRKENCGSVP 138
           CLNG TC   LG+ FC C P F G +CE  +  + C S P
Sbjct: 233 CLNGATCQDALGAYFCDCAPGFLGDHCE--LNTDECASQP 270



 Score = 27.7 bits (60), Expect = 6.5
 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 5/49 (10%)

Query: 93  DSKEPNRTCCLNGGTC---MLGSFCACLPSFYGWNCEHGVRKENCGSVP 138
           D  E   + C NG  C   + G  C C+P + G +C+  +  + C S P
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCD--LEVDECASDP 194


>gi|55770876 notch4 preproprotein [Homo sapiens]
          Length = 2003

 Score = 35.4 bits (80), Expect = 0.031
 Identities = 26/67 (38%), Positives = 29/67 (43%), Gaps = 11/67 (16%)

Query: 102  CLNGGTCML---GSFCACLPSFYGWNCEHGVRKENCGSVP---HDTRLPKKCSM-CKCWH 154
            C NG TCM    G  C C P + G NC   +  + C S P   H T  PK     C C  
Sbjct: 939  CQNGATCMAQPSGYLCQCAPGYDGQNCSKEL--DACQSQPCHNHGTCTPKPGGFHCACPP 996

Query: 155  G--QLRC 159
            G   LRC
Sbjct: 997  GFVGLRC 1003



 Score = 32.3 bits (72), Expect = 0.26
 Identities = 18/42 (42%), Positives = 20/42 (47%), Gaps = 9/42 (21%)

Query: 102 CLNGGTCML-------GSFCACLPSFYGWNCEHGVRKENCGS 136
           C NGGTC L          C C P F G +CE  V  +NC S
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE--VNPDNCVS 282



 Score = 32.0 bits (71), Expect = 0.34
 Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 3/41 (7%)

Query: 102 CLNGGTCMLGS---FCACLPSFYGWNCEHGVRKENCGSVPH 139
           C NGGTC  G     C C  ++ GW+C   V +      PH
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPH 325



 Score = 32.0 bits (71), Expect = 0.34
 Identities = 32/102 (31%), Positives = 35/102 (34%), Gaps = 29/102 (28%)

Query: 102  CLNGGTCM------LGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHG 155
            C +GGTC       LG  C C   F G  C H              R P  C    C HG
Sbjct: 1055 CFHGGTCEATAGSPLGFICHCPKGFEGPTCSH--------------RAP-SCGFHHCHHG 1099

Query: 156  QLRCFPQ---AFLPGCDGL--VMDEHLMAPRTPE--LPPSAC 190
             L C P     F P C  L        + P  P+   PPS C
Sbjct: 1100 GL-CLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC 1140



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 36/127 (28%), Positives = 45/127 (35%), Gaps = 38/127 (29%)

Query: 85  LVPPMGIQDSKEPNRTCCLNGGTCMLGSF----CACLPSFYGWN------CEHGVRKENC 134
           +V P G+     P    C NGGTC+  S     C C P F G        C++    +N 
Sbjct: 20  VVRPRGLLCGSFPEP--CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNG 77

Query: 135 GS----VPHDTRLPKKCS------MCKCWHGQLRCFPQAFLPGCDGLVMDEHLMAPRTPE 184
           GS    +P    LP   S      +C C            LPG  G    E   A     
Sbjct: 78  GSCQALLPAPLGLPSSPSPLTPSFLCTC------------LPGFTG----ERCQAKLEDP 121

Query: 185 LPPSACT 191
            PPS C+
Sbjct: 122 CPPSFCS 128



 Score = 31.6 bits (70), Expect = 0.45
 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 5/50 (10%)

Query: 92  QDSKEPNRTCCLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
           +D  E   + C NGG C    G+F C CLP F G  C+  V  + C S P
Sbjct: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV--DECLSDP 597



 Score = 31.2 bits (69), Expect = 0.58
 Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 5/40 (12%)

Query: 102 CLNGGTC--MLGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
           CLN   C  +L  F C CLP F G  CE  +  + C S P
Sbjct: 522 CLNHADCHDLLNGFQCICLPGFSGTRCEEDI--DECRSSP 559



 Score = 30.8 bits (68), Expect = 0.76
 Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 4/40 (10%)

Query: 102 CLNGGTCM--LGSF-CACLPSFYGWNCEHGVRKENCGSVP 138
           C NGGTC+   G+F C C   F G  CE G  + +C   P
Sbjct: 776 CFNGGTCVNRPGTFSCLCAMGFQGPRCE-GKLRPSCADSP 814



 Score = 30.4 bits (67), Expect = 1.00
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 5/40 (12%)

Query: 102 CLNGGTCML---GSFCACLPSFYGWNCEHGVRKENCGSVP 138
           CLNGG+C     G +C C PS  G  C+     + C S P
Sbjct: 738 CLNGGSCNPSPGGYYCTCPPSHTGPQCQ--TSTDYCVSAP 775



 Score = 30.4 bits (67), Expect = 1.00
 Identities = 23/64 (35%), Positives = 27/64 (42%), Gaps = 8/64 (12%)

Query: 102  CLNGGTCML---GSFCACLPSFYGWNCEHGVRKENCGSVP-HDTRLPKKCSMCKCWHGQL 157
            C N GTC     G  CAC P F G  CE  V  + C   P H T      S+   ++ Q 
Sbjct: 977  CHNHGTCTPKPGGFHCACPPGFVGLRCEGDV--DECLDQPCHPTGTAACHSLANAFYCQ- 1033

Query: 158  RCFP 161
             C P
Sbjct: 1034 -CLP 1036



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 7/57 (12%)

Query: 102 CLNGGTCMLGSF----CACLPSFYGWNCEHGVRK--ENCGSVPHDTRLPKKCSMCKC 152
           C+NGG C L ++    C C P F G  CE  V +  ++ G  P  T         +C
Sbjct: 165 CVNGGVC-LATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC 220



 Score = 27.3 bits (59), Expect = 8.4
 Identities = 16/40 (40%), Positives = 18/40 (45%), Gaps = 5/40 (12%)

Query: 102 CLNGGTCMLGS---FCACLPSFYGWNCEHGVRKENCGSVP 138
           C NGG C+      FC C P F G  C+  V    C S P
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNP--CESRP 938


>gi|148886654 polydom [Homo sapiens]
          Length = 3571

 Score = 35.4 bits (80), Expect = 0.031
 Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 1/54 (1%)

Query: 102  CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHG 155
            CLNGG C+    C C P + G  C   V +  C +     R P +C     W G
Sbjct: 3508 CLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVR-PNRCHCLSSWTG 3560



 Score = 33.9 bits (76), Expect = 0.090
 Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 3/34 (8%)

Query: 102  CLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCG 135
            CLNGG C+  + C CL S+ G NC    RK   G
Sbjct: 3540 CLNGGKCVRPNRCHCLSSWTGHNCS---RKRRTG 3570



 Score = 30.4 bits (67), Expect = 1.00
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 11/93 (11%)

Query: 92   QDSKEPNRTCCLNGGTCM---LGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCS 148
            ++  E + + CLN G C+    G  C C+  F G +CE  V +  C S P         +
Sbjct: 1268 ENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNE--CQSNPCLNN-----A 1320

Query: 149  MCKCWHGQLRC-FPQAFLPGCDGLVMDEHLMAP 180
            +C+   G   C  P  FL    G  +DE L  P
Sbjct: 1321 VCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQP 1353



 Score = 27.7 bits (60), Expect = 6.5
 Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 21/101 (20%)

Query: 99   RTCCLNGGTCMLGSFCACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLR 158
            R+ CL  GT      C  +  F    C++G   +           P  CS  + W G+L 
Sbjct: 3453 RSVCLENGTWTSPPICRAVCRF---PCQNGGICQR----------PNACSCPEGWMGRLC 3499

Query: 159  CFPQAFLPGCDGLVMDEHLMAPRTPELPP----SACTTFIC 195
              P   LP  +G       +AP   + PP    S C T +C
Sbjct: 3500 EEPICILPCLNG----GRCVAPYQCDCPPGWTGSRCHTAVC 3536


>gi|20127446 integrin, beta 5 [Homo sapiens]
          Length = 799

 Score = 35.0 bits (79), Expect = 0.040
 Identities = 32/138 (23%), Positives = 51/138 (36%), Gaps = 30/138 (21%)

Query: 58  VKEGDLAFRDDSIQPQEEPAIRPRSSQLVPPMGIQDSKE----------------PNRTC 101
           +K GD A  + S++ +  P+        + P+G +DS E                PN   
Sbjct: 416 LKIGDTASFEVSLEARSCPSRHTEHVFALRPVGFRDSLEVGVTYNCTCGCSVGLEPNSAR 475

Query: 102 CLNGGTCMLGSFCACLPSFYGWNCE----------HGVRKENCGSVPHDTRLPKKCSMCK 151
           C   GT + G  C C P + G  CE            + +E  G      R    C+ C 
Sbjct: 476 CNGSGTYVCG-LCECSPGYLGTRCECQDGENQSVYQNLCREAEGKPLCSGRGDCSCNQCS 534

Query: 152 CWHGQLRCFPQAFLPGCD 169
           C+  +   F + + P C+
Sbjct: 535 CFESE---FGKIYGPFCE 549


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.464 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,364,072
Number of Sequences: 37866
Number of extensions: 459068
Number of successful extensions: 1708
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 1329
Number of HSP's gapped (non-prelim): 441
length of query: 195
length of database: 18,247,518
effective HSP length: 97
effective length of query: 98
effective length of database: 14,574,516
effective search space: 1428302568
effective search space used: 1428302568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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