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Search of human proteins with 167900452
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167900452 phospholipase C-like 1 isoform a [Homo sapiens]
(1095 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167900452 phospholipase C-like 1 isoform a [Homo sapiens] 2196 0.0
gi|167900450 phospholipase C-like 1 isoform b [Homo sapiens] 2001 0.0
gi|221219000 phospholipase C-like 2 isoform 1 [Homo sapiens] 1410 0.0
gi|163644311 phospholipase C-like 2 isoform 2 [Homo sapiens] 1374 0.0
gi|14249340 phospholipase C, delta 4 [Homo sapiens] 480 e-135
gi|90265805 phospholipase C, delta 1 isoform 2 [Homo sapiens] 466 e-131
gi|195972883 phospholipase C, delta 1 isoform 1 [Homo sapiens] 466 e-131
gi|25188201 phospholipase C, zeta 1 [Homo sapiens] 436 e-122
gi|19115964 phospholipase C delta 3 [Homo sapiens] 422 e-117
gi|78499633 phospholipase C, eta 2 [Homo sapiens] 350 4e-96
gi|195972873 phospholipase C eta 1 isoform c [Homo sapiens] 339 1e-92
gi|195972871 phospholipase C eta 1 isoform a [Homo sapiens] 339 1e-92
gi|57863298 phospholipase C eta 1 isoform b [Homo sapiens] 335 1e-91
gi|12083581 phosphoinositide-specific phospholipase C beta 1 iso... 332 2e-90
gi|33356544 phosphoinositide-specific phospholipase C beta 1 iso... 332 2e-90
gi|33469933 phospholipase C beta 4 isoform a [Homo sapiens] 328 1e-89
gi|33469939 phospholipase C beta 4 isoform b [Homo sapiens] 328 1e-89
gi|95147333 phospholipase C, beta 2 [Homo sapiens] 279 9e-75
gi|117320537 phospholipase C, gamma 2 [Homo sapiens] 199 9e-51
gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens] 186 1e-46
gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens] 185 2e-46
gi|11386139 phospholipase C beta 3 [Homo sapiens] 184 3e-46
gi|117168250 phospholipase C, epsilon 1 [Homo sapiens] 162 1e-39
gi|61742814 coiled-coil and C2 domain containing 1B [Homo sapiens] 43 0.001
gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens] 43 0.002
gi|47078261 double C2-like domains, alpha [Homo sapiens] 42 0.002
gi|38201692 RAS p21 protein activator 3 [Homo sapiens] 42 0.004
gi|209447073 synaptotagmin I [Homo sapiens] 40 0.012
gi|5032139 synaptotagmin I [Homo sapiens] 40 0.012
gi|209447070 synaptotagmin I [Homo sapiens] 40 0.012
>gi|167900452 phospholipase C-like 1 isoform a [Homo sapiens]
Length = 1095
Score = 2196 bits (5690), Expect = 0.0
Identities = 1095/1095 (100%), Positives = 1095/1095 (100%)
Query: 1 MAEGAAGREDPAPPDAAGGEDDPRVGPDAAGDCVTAASGGRMRDRRSGVALPGAAGTPAD 60
MAEGAAGREDPAPPDAAGGEDDPRVGPDAAGDCVTAASGGRMRDRRSGVALPGAAGTPAD
Sbjct: 1 MAEGAAGREDPAPPDAAGGEDDPRVGPDAAGDCVTAASGGRMRDRRSGVALPGAAGTPAD 60
Query: 61 SEAGLLEAARATPRRSSIIKDPSNQKCGGRKKTVSFSSMPSEKKISSANDCISFMQAGCE 120
SEAGLLEAARATPRRSSIIKDPSNQKCGGRKKTVSFSSMPSEKKISSANDCISFMQAGCE
Sbjct: 61 SEAGLLEAARATPRRSSIIKDPSNQKCGGRKKTVSFSSMPSEKKISSANDCISFMQAGCE 120
Query: 121 LKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGL 180
LKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGL
Sbjct: 121 LKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGL 180
Query: 181 ADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPR 240
ADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPR
Sbjct: 181 ADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPR 240
Query: 241 FMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTRVTE 300
FMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTRVTE
Sbjct: 241 FMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTRVTE 300
Query: 301 EEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDICLDIIRRY 360
EEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDICLDIIRRY
Sbjct: 301 EEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDICLDIIRRY 360
Query: 361 ELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIED 420
ELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIED
Sbjct: 361 ELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIED 420
Query: 421 QFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIEVINKFAF 480
QFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIEVINKFAF
Sbjct: 421 QFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIEVINKFAF 480
Query: 481 VASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSESYLPSPEKLKRMIIVK 540
VASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSESYLPSPEKLKRMIIVK
Sbjct: 481 VASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSESYLPSPEKLKRMIIVK 540
Query: 541 GKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGEQKQIRLCRELSDLVSICKSVQYRDF 600
GKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGEQKQIRLCRELSDLVSICKSVQYRDF
Sbjct: 541 GKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGEQKQIRLCRELSDLVSICKSVQYRDF 600
Query: 601 ELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFW 660
ELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFW
Sbjct: 601 ELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFW 660
Query: 661 NCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSP 720
NCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSP
Sbjct: 661 NCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSP 720
Query: 721 LALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDE 780
LALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDE
Sbjct: 721 LALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDE 780
Query: 781 TFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVT 840
TFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVT
Sbjct: 781 TFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVT 840
Query: 841 LFVHIAITNRSGGGKAQKRSLSVRMGKKVREYTMLRNIGLKTIDDIFKIAVHPLREAIDM 900
LFVHIAITNRSGGGKAQKRSLSVRMGKKVREYTMLRNIGLKTIDDIFKIAVHPLREAIDM
Sbjct: 841 LFVHIAITNRSGGGKAQKRSLSVRMGKKVREYTMLRNIGLKTIDDIFKIAVHPLREAIDM 900
Query: 901 RENMQNAIVSIKELCGLPPIASLKQCLLTLSSRLITSDNTPSVSLVMKDSFPYLEPLGAI 960
RENMQNAIVSIKELCGLPPIASLKQCLLTLSSRLITSDNTPSVSLVMKDSFPYLEPLGAI
Sbjct: 901 RENMQNAIVSIKELCGLPPIASLKQCLLTLSSRLITSDNTPSVSLVMKDSFPYLEPLGAI 960
Query: 961 PDVQKKMLTAYDLMIQESRFLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKL 1020
PDVQKKMLTAYDLMIQESRFLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKL
Sbjct: 961 PDVQKKMLTAYDLMIQESRFLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKL 1020
Query: 1021 NKATESFAWNITVLKGQGDLLKNAKNEAIENMKQIQLACLSCGLSKAPSSSAEAKSKRSL 1080
NKATESFAWNITVLKGQGDLLKNAKNEAIENMKQIQLACLSCGLSKAPSSSAEAKSKRSL
Sbjct: 1021 NKATESFAWNITVLKGQGDLLKNAKNEAIENMKQIQLACLSCGLSKAPSSSAEAKSKRSL 1080
Query: 1081 EAIEEKESSEENGKL 1095
EAIEEKESSEENGKL
Sbjct: 1081 EAIEEKESSEENGKL 1095
>gi|167900450 phospholipase C-like 1 isoform b [Homo sapiens]
Length = 997
Score = 2001 bits (5185), Expect = 0.0
Identities = 997/997 (100%), Positives = 997/997 (100%)
Query: 99 MPSEKKISSANDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKL 158
MPSEKKISSANDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKL
Sbjct: 1 MPSEKKISSANDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKL 60
Query: 159 DISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGL 218
DISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGL
Sbjct: 61 DISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGL 120
Query: 219 RYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEA 278
RYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEA
Sbjct: 121 RYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEA 180
Query: 279 KIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLF 338
KIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLF
Sbjct: 181 KIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLF 240
Query: 339 LEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQ 398
LEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQ
Sbjct: 241 LEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQ 300
Query: 399 DMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCN 458
DMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCN
Sbjct: 301 DMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCN 360
Query: 459 RNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTE 518
RNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTE
Sbjct: 361 RNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTE 420
Query: 519 APLPSESYLPSPEKLKRMIIVKGKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGEQKQ 578
APLPSESYLPSPEKLKRMIIVKGKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGEQKQ
Sbjct: 421 APLPSESYLPSPEKLKRMIIVKGKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGEQKQ 480
Query: 579 IRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKF 638
IRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKF
Sbjct: 481 IRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKF 540
Query: 639 LSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPS 698
LSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPS
Sbjct: 541 LSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPS 600
Query: 699 IMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIP 758
IMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIP
Sbjct: 601 IMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIP 660
Query: 759 ADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFEC 818
ADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFEC
Sbjct: 661 ADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFEC 720
Query: 819 LQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKVREYTMLRNI 878
LQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKVREYTMLRNI
Sbjct: 721 LQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKVREYTMLRNI 780
Query: 879 GLKTIDDIFKIAVHPLREAIDMRENMQNAIVSIKELCGLPPIASLKQCLLTLSSRLITSD 938
GLKTIDDIFKIAVHPLREAIDMRENMQNAIVSIKELCGLPPIASLKQCLLTLSSRLITSD
Sbjct: 781 GLKTIDDIFKIAVHPLREAIDMRENMQNAIVSIKELCGLPPIASLKQCLLTLSSRLITSD 840
Query: 939 NTPSVSLVMKDSFPYLEPLGAIPDVQKKMLTAYDLMIQESRFLIEMADTVQEKIVQCQKA 998
NTPSVSLVMKDSFPYLEPLGAIPDVQKKMLTAYDLMIQESRFLIEMADTVQEKIVQCQKA
Sbjct: 841 NTPSVSLVMKDSFPYLEPLGAIPDVQKKMLTAYDLMIQESRFLIEMADTVQEKIVQCQKA 900
Query: 999 GMEFHEELHNLGAKEGLKGRKLNKATESFAWNITVLKGQGDLLKNAKNEAIENMKQIQLA 1058
GMEFHEELHNLGAKEGLKGRKLNKATESFAWNITVLKGQGDLLKNAKNEAIENMKQIQLA
Sbjct: 901 GMEFHEELHNLGAKEGLKGRKLNKATESFAWNITVLKGQGDLLKNAKNEAIENMKQIQLA 960
Query: 1059 CLSCGLSKAPSSSAEAKSKRSLEAIEEKESSEENGKL 1095
CLSCGLSKAPSSSAEAKSKRSLEAIEEKESSEENGKL
Sbjct: 961 CLSCGLSKAPSSSAEAKSKRSLEAIEEKESSEENGKL 997
>gi|221219000 phospholipase C-like 2 isoform 1 [Homo sapiens]
Length = 1127
Score = 1410 bits (3649), Expect = 0.0
Identities = 713/1122 (63%), Positives = 859/1122 (76%), Gaps = 40/1122 (3%)
Query: 4 GAAGREDPAPPDAA-------------GGEDDPRVGPDAA---------GDCVTAASGGR 41
GAAG P P A GG R+G A GDC SG
Sbjct: 8 GAAGGALPTSPGPALGAKGALKAGVGEGGGGGGRLGHGRARYDSGGVSNGDCSLGVSGDE 67
Query: 42 MRDRRS----GVALPGAAGTPADSEAGLLEAAR--ATPRRSSIIKDPSNQKCGGRKKTVS 95
R + GVAL A TP+ L ++ PRRSSIIKD + QK RKKTVS
Sbjct: 68 ARASPTRGPRGVAL---APTPSAVVCTLPRESKPGGLPRRSSIIKDGTKQK-RERKKTVS 123
Query: 96 FSSMPSEKKISSANDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEK 155
FSSMP+EKKISSA+DCI+ M G ELKKVR NSRIY+R+F LD D+Q+LRWEPSKKD EK
Sbjct: 124 FSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEK 183
Query: 156 AKLDISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWV 215
AK+DI +IKE+R GKNT+ FR+NG++DQI EDCAFS+++GENYESLDLVANSADVANIWV
Sbjct: 184 AKIDIKSIKEVRTGKNTDIFRSNGISDQISEDCAFSVIYGENYESLDLVANSADVANIWV 243
Query: 216 SGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTL 275
+GLRYL+S K LD +E +Q+ R W+ +F DVD G + +V+ I+ LNP L
Sbjct: 244 TGLRYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNAVQCIRNLNPGL 303
Query: 276 KEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDL 335
K +KI LKFKE+ KSK+K T VT+EEF E F ELCTRPE+YFLLVQ S NKE+LD DL
Sbjct: 304 KTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELCTRPEIYFLLVQFSSNKEFLDTKDL 363
Query: 336 MLFLEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKK 395
M+FLEAEQGV HI E+I L+II +YE S+EG++KG+L+IDGFT YL+S +C IFDPE KK
Sbjct: 364 MMFLEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKK 423
Query: 396 VAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPI 455
V QDM QPLSHY+IN+SHNTYLIEDQFRGP+DI GYIRALKMGCRSVELDV DG DNEP+
Sbjct: 424 VCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPV 483
Query: 456 LCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKL 515
+ + MT+ + FRSVI++INK+AF ASEYPLILCL NHCS+ QQKVM Q MKK+ G+KL
Sbjct: 484 IYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKLLGDKL 543
Query: 516 YTEAPLPSESYLPSPEKLKRMIIVKGKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGE 575
YT +P ESYLPSP+ LK I++K KKL S+ +EG+VTDEDE AEMS+RM + N E
Sbjct: 544 YTTSPNVEESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDEGAEMSQRMGKE-NME 602
Query: 576 Q------KQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPE 629
Q K+ +LC+ELS+LVSICKSVQ+++F++S + Q YWE+CSF+E AS+ ANE P
Sbjct: 603 QPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPG 662
Query: 630 DFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNG 689
DFVNYNK+FL+R++PS MRIDSSN+NPQDFW CGCQIVAMNFQTPG MMDL+ GWF QNG
Sbjct: 663 DFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNG 722
Query: 690 GCGYVLRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPY 749
CGYVLRP+IMR+EVS+FSANTK +PGVSP LHIKIISGQNFPKPKG+ AKGDV+DPY
Sbjct: 723 NCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPY 782
Query: 750 VCIEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIGDEFI 809
V +EIHGIPADC+EQRTKTV QN D PIFDE+FEFQ+NLPELAM+RFVVLDDDYIGDEFI
Sbjct: 783 VYVEIHGIPADCAEQRTKTVHQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGDEFI 842
Query: 810 GQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKV 869
GQYTIPFECLQ GYRHVPL+S G+++ H +LFVH+AITNR GGGK KR LSVR GKK
Sbjct: 843 GQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKS 902
Query: 870 REYTMLRNIGLKTIDDIFKIAVHPLREAIDMRENMQNAIVSIKELCGLPPIASLKQCLLT 929
REY LR + +KT+D++FK A P+R+A D+RENMQNA+VS KELCGL +A+L QC+L
Sbjct: 903 REYASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLA 962
Query: 930 LSSRLITSDNTPSVSLVMKDSFPYLEPLGAIPDVQKKMLTAYDLMIQESRFLIEMADTVQ 989
+S R + DNTP V L + + +P +E G +P+V KK++T YD+MIQ + LIE AD V
Sbjct: 963 VSPRFLGPDNTPLVVLNLSEQYPTMELQGIVPEVLKKIVTTYDMMIQSLKALIENADAVY 1022
Query: 990 EKIVQCQKAGMEFHEELHNLGAKEGLKGRKLNKATESFAWNITVLKGQGDLLKNAKNEAI 1049
EKIV CQKA MEFHE LH++G KEGLK RKL KA ESF WNIT+LKGQ DLLK AKNE +
Sbjct: 1023 EKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETL 1082
Query: 1050 ENMKQIQLACLSCGLSKAPSSSAEA-KSKRSLEAIEEKESSE 1090
EN+KQI A +SCGL+K + +A+ K +RSLE I EK + E
Sbjct: 1083 ENLKQIHFAAVSCGLNKPGTENADVQKPRRSLEVIPEKANDE 1124
>gi|163644311 phospholipase C-like 2 isoform 2 [Homo sapiens]
Length = 1001
Score = 1374 bits (3556), Expect = 0.0
Identities = 667/999 (66%), Positives = 807/999 (80%), Gaps = 8/999 (0%)
Query: 99 MPSEKKISSANDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKL 158
MP+EKKISSA+DCI+ M G ELKKVR NSRIY+R+F LD D+Q+LRWEPSKKD EKAK+
Sbjct: 1 MPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEKAKI 60
Query: 159 DISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGL 218
DI +IKE+R GKNT+ FR+NG++DQI EDCAFS+++GENYESLDLVANSADVANIWV+GL
Sbjct: 61 DIKSIKEVRTGKNTDIFRSNGISDQISEDCAFSVIYGENYESLDLVANSADVANIWVTGL 120
Query: 219 RYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEA 278
RYL+S K LD +E +Q+ R W+ +F DVD G + +V+ I+ LNP LK +
Sbjct: 121 RYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNAVQCIRNLNPGLKTS 180
Query: 279 KIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLF 338
KI LKFKE+ KSK+K T VT+EEF E F ELCTRPE+YFLLVQ S NKE+LD DLM+F
Sbjct: 181 KIELKFKELHKSKDKAGTEVTKEEFIEVFHELCTRPEIYFLLVQFSSNKEFLDTKDLMMF 240
Query: 339 LEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQ 398
LEAEQGV HI E+I L+II +YE S+EG++KG+L+IDGFT YL+S +C IFDPE KKV Q
Sbjct: 241 LEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQ 300
Query: 399 DMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCN 458
DM QPLSHY+IN+SHNTYLIEDQFRGP+DI GYIRALKMGCRSVELDV DG DNEP++
Sbjct: 301 DMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYT 360
Query: 459 RNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTE 518
+ MT+ + FRSVI++INK+AF ASEYPLILCL NHCS+ QQKVM Q MKK+ G+KLYT
Sbjct: 361 GHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKLLGDKLYTT 420
Query: 519 APLPSESYLPSPEKLKRMIIVKGKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGEQ-- 576
+P ESYLPSP+ LK I++K KKL S+ +EG+VTDEDE AEMS+RM + N EQ
Sbjct: 421 SPNVEESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDEGAEMSQRMGKE-NMEQPN 479
Query: 577 ----KQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPEDFV 632
K+ +LC+ELS+LVSICKSVQ+++F++S + Q YWE+CSF+E AS+ ANE P DFV
Sbjct: 480 NVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDFV 539
Query: 633 NYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCG 692
NYNK+FL+R++PS MRIDSSN+NPQDFW CGCQIVAMNFQTPG MMDL+ GWF QNG CG
Sbjct: 540 NYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCG 599
Query: 693 YVLRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCI 752
YVLRP+IMR+EVS+FSANTK +PGVSP LHIKIISGQNFPKPKG+ AKGDV+DPYV +
Sbjct: 600 YVLRPAIMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYV 659
Query: 753 EIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIGDEFIGQY 812
EIHGIPADC+EQRTKTV QN D PIFDE+FEFQ+NLPELAM+RFVVLDDDYIGDEFIGQY
Sbjct: 660 EIHGIPADCAEQRTKTVHQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGDEFIGQY 719
Query: 813 TIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKVREY 872
TIPFECLQ GYRHVPL+S G+++ H +LFVH+AITNR GGGK KR LSVR GKK REY
Sbjct: 720 TIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKSREY 779
Query: 873 TMLRNIGLKTIDDIFKIAVHPLREAIDMRENMQNAIVSIKELCGLPPIASLKQCLLTLSS 932
LR + +KT+D++FK A P+R+A D+RENMQNA+VS KELCGL +A+L QC+L +S
Sbjct: 780 ASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSP 839
Query: 933 RLITSDNTPSVSLVMKDSFPYLEPLGAIPDVQKKMLTAYDLMIQESRFLIEMADTVQEKI 992
R + DNTP V L + + +P +E G +P+V KK++T YD+MIQ + LIE AD V EKI
Sbjct: 840 RFLGPDNTPLVVLNLSEQYPTMELQGIVPEVLKKIVTTYDMMIQSLKALIENADAVYEKI 899
Query: 993 VQCQKAGMEFHEELHNLGAKEGLKGRKLNKATESFAWNITVLKGQGDLLKNAKNEAIENM 1052
V CQKA MEFHE LH++G KEGLK RKL KA ESF WNIT+LKGQ DLLK AKNE +EN+
Sbjct: 900 VHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETLENL 959
Query: 1053 KQIQLACLSCGLSKAPSSSAEA-KSKRSLEAIEEKESSE 1090
KQI A +SCGL+K + +A+ K +RSLE I EK + E
Sbjct: 960 KQIHFAAVSCGLNKPGTENADVQKPRRSLEVIPEKANDE 998
>gi|14249340 phospholipase C, delta 4 [Homo sapiens]
Length = 762
Score = 480 bits (1236), Expect = e-135
Identities = 288/753 (38%), Positives = 426/753 (56%), Gaps = 37/753 (4%)
Query: 115 MQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTET 174
MQ G ++KVR S R+F L D + + K IS ++ IR G ++E
Sbjct: 18 MQEGMPMRKVRSKSWKKLRYFRLQNDGMTVWHARQARGSAKPSFSISDVETIRNGHDSEL 77
Query: 175 FRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEG 234
R+ LA+++ + F+I+ +LDL+ANS + A IW+ GL+ LV D +
Sbjct: 78 LRS--LAEELPLEQGFTIVFHGRRSNLDLMANSVEEAQIWMRGLQLLV-------DLVTS 128
Query: 235 NQNTPRF-MWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEK 293
+ R WL F+ D + +G M L+ +N + + F Q +
Sbjct: 129 MDHQERLDQWLSDWFQRGDKNQDGKMSFQEVQRLLHLMNVEMDQ---EYAFSLFQAADTS 185
Query: 294 LTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDIC 353
+ + EEF + + L R EV L S + + L + + FL+ EQ T ++
Sbjct: 186 QSGTLEGEEFVQFYKALTKRAEVQELFESFSADGQKLTLLEFLDFLQEEQKERDCTSELA 245
Query: 354 LDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASH 413
L++I RYE S+ G+ + L++DGF YL S + DIF+P + QDMTQPL+HY+I +SH
Sbjct: 246 LELIDRYEPSDSGKLRHVLSMDGFLSYLCSKDGDIFNPACLPIYQDMTQPLNHYFICSSH 305
Query: 414 NTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIE 473
NTYL+ DQ G + + GYIRALK GCR VE+DV DG EP++ + + +T+ + F+ V+
Sbjct: 306 NTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVWDGPSGEPVVYHGHTLTSRILFKDVVA 365
Query: 474 VINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYT---EAPLPSESYLPSP 530
+ ++AF S+YP+IL L HCS QQ+ MA+ + ++ G +L + + LP++ LPSP
Sbjct: 366 TVAQYAFQTSDYPVILSLETHCSWEQQQTMARHLTEILGEQLLSTTLDGVLPTQ--LPSP 423
Query: 531 EKLKRMIIVKGKKLPSDPDV--LEGEVTDEDEEAEMSRRMSVDYNGEQKQIR-------- 580
E+L+R I+VKGKKL + D+ E E E EE+E++ + E ++
Sbjct: 424 EELRRKILVKGKKLTLEEDLEYEEEEAEPELEESELALESQFETEPEPQEQNLQNKDKKK 483
Query: 581 -----LCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYN 635
LC LS LV KSV +R F S + +++E+ SFSET+A R+ E +FV +N
Sbjct: 484 KSKPILCPALSSLVIYLKSVSFRSFTHSKEHYHFYEISSFSETKAKRLIKEAGNEFVQHN 543
Query: 636 KKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVL 695
LSR+YPS +R DSSN NPQ+ WN GCQ+VAMN QT G MD+ G F QNGGCGYVL
Sbjct: 544 TWQLSRVYPSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGGCGYVL 603
Query: 696 RPSIMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIH 755
+P +RD S F K I P L I++ISGQ PK +G ++DP V ++I
Sbjct: 604 KPDFLRDIQSSFHPE-KPISP-FKAQTLLIQVISGQQLPK-VDKTKEGSIVDPLVKVQIF 660
Query: 756 GIPADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIG-DEFIGQYTI 814
G+ D + Q T V+ N NP + +T F+V +PELAM+RFVV+D D+ ++FIGQYT+
Sbjct: 661 GVRLDTARQETNYVENNGFNPYWGQTLCFRVLVPELAMLRFVVMDYDWKSRNDFIGQYTL 720
Query: 815 PFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAI 847
P+ C+Q GYRH+ L S G + ++FV+I I
Sbjct: 721 PWTCMQQGYRHIHLLSKDGISLRPASIFVYICI 753
>gi|90265805 phospholipase C, delta 1 isoform 2 [Homo sapiens]
Length = 756
Score = 466 bits (1199), Expect = e-131
Identities = 291/745 (39%), Positives = 412/745 (55%), Gaps = 30/745 (4%)
Query: 118 GCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDL---EKAKLDISAIKEIRLGKNTET 174
G +L KV+ +S RF+ L D + + W+ S+K + E I I+E+R+G TE
Sbjct: 25 GSQLLKVKSSSWRRERFYKLQEDCKTI-WQESRKVMRTPESQLFSIEDIQEVRMGHRTEG 83
Query: 175 FRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEG 234
A + ED FSI+ + +LDL+A S A WV GL ++ S M+
Sbjct: 84 LEK--FARDVPEDRCFSIVFKDQRNTLDLIAPSPADAQHWVLGLHKIIHHSGS----MDQ 137
Query: 235 NQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKL 294
Q W+ + AD + + M +K+LN + ++ R F+E S+
Sbjct: 138 RQKLQH--WIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSYARKIFRECDHSQ--- 192
Query: 295 TTRVTEEEFCEAFCELCT-RPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDIC 353
T E+E EAF ++ T R E+ + + + E L + L+ FL+ +Q +
Sbjct: 193 -TDSLEDEEIEAFYKMLTQRVEIDRTFAEAAGSGETLSVDQLVTFLQHQQREEAAGPALA 251
Query: 354 LDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASH 413
L +I RYE SE + + + DGF YLLS++ F ++V QDM QPLSHY +++SH
Sbjct: 252 LSLIERYEPSETAKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQPLSHYLVSSSH 311
Query: 414 NTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIE 473
NTYL+EDQ GP+ YIRAL GCR +ELD DG + EPI+ + T+ + F V+
Sbjct: 312 NTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLR 371
Query: 474 VINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSESYLPSPEKL 533
I +AF AS YP+IL L NHC+L QQ+VMA+ + + G L + LPSPE+L
Sbjct: 372 AIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILGPMLLNRPLDGVTNSLPSPEQL 431
Query: 534 KRMIIVKGKKLPS-DPDVLEG-----EVTDEDEEAEM---SRRMSVDYNGEQKQIRLCRE 584
K I++KGKKL P EG V+DEDE AEM + R V + ++ ++RL +E
Sbjct: 432 KGKILLKGKKLGGLLPPGGEGGPEATVVSDEDEAAEMEDEAVRSRVQHKPKEDKLRLAQE 491
Query: 585 LSDLVSICKSVQYRDFEL-SMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIY 643
LSD+V CKSV + F Q ++EM SFSE A R+ E FV +N LSRIY
Sbjct: 492 LSDMVIYCKSVHFGGFSSPGTPGQAFYEMASFSENRALRLLQESGNGFVRHNVGHLSRIY 551
Query: 644 PSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDE 703
P+ R DSSN +P + WN GCQIVA+NFQTPGP MD++ G F NG CGYVL+P+ +RD
Sbjct: 552 PAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQGRFQDNGACGYVLKPAFLRDP 611
Query: 704 VSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSE 763
F+ P + L+I++ISGQ PK K ++DP V +EIHG+ D +
Sbjct: 612 NGTFNPRALAQGPWWARKRLNIRVISGQQLPKVNK--NKNSIVDPKVTVEIHGVSRDVAS 669
Query: 764 QRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIG-DEFIGQYTIPFECLQPG 822
++T + N NP +D F F+V +P+LA+IRF+V D D ++FIGQ TIP L+ G
Sbjct: 670 RQTAVITNNGFNPWWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIPLNSLKQG 729
Query: 823 YRHVPLRSFVGDIMEHVTLFVHIAI 847
YRHV L S GD TLFV I++
Sbjct: 730 YRHVHLMSKNGDQHPSATLFVKISL 754
>gi|195972883 phospholipase C, delta 1 isoform 1 [Homo sapiens]
Length = 777
Score = 466 bits (1199), Expect = e-131
Identities = 291/745 (39%), Positives = 412/745 (55%), Gaps = 30/745 (4%)
Query: 118 GCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDL---EKAKLDISAIKEIRLGKNTET 174
G +L KV+ +S RF+ L D + + W+ S+K + E I I+E+R+G TE
Sbjct: 46 GSQLLKVKSSSWRRERFYKLQEDCKTI-WQESRKVMRTPESQLFSIEDIQEVRMGHRTEG 104
Query: 175 FRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEG 234
A + ED FSI+ + +LDL+A S A WV GL ++ S M+
Sbjct: 105 LEK--FARDVPEDRCFSIVFKDQRNTLDLIAPSPADAQHWVLGLHKIIHHSGS----MDQ 158
Query: 235 NQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKL 294
Q W+ + AD + + M +K+LN + ++ R F+E S+
Sbjct: 159 RQKLQH--WIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSYARKIFRECDHSQ--- 213
Query: 295 TTRVTEEEFCEAFCELCT-RPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDIC 353
T E+E EAF ++ T R E+ + + + E L + L+ FL+ +Q +
Sbjct: 214 -TDSLEDEEIEAFYKMLTQRVEIDRTFAEAAGSGETLSVDQLVTFLQHQQREEAAGPALA 272
Query: 354 LDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASH 413
L +I RYE SE + + + DGF YLLS++ F ++V QDM QPLSHY +++SH
Sbjct: 273 LSLIERYEPSETAKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQPLSHYLVSSSH 332
Query: 414 NTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIE 473
NTYL+EDQ GP+ YIRAL GCR +ELD DG + EPI+ + T+ + F V+
Sbjct: 333 NTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLR 392
Query: 474 VINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSESYLPSPEKL 533
I +AF AS YP+IL L NHC+L QQ+VMA+ + + G L + LPSPE+L
Sbjct: 393 AIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILGPMLLNRPLDGVTNSLPSPEQL 452
Query: 534 KRMIIVKGKKLPS-DPDVLEG-----EVTDEDEEAEM---SRRMSVDYNGEQKQIRLCRE 584
K I++KGKKL P EG V+DEDE AEM + R V + ++ ++RL +E
Sbjct: 453 KGKILLKGKKLGGLLPPGGEGGPEATVVSDEDEAAEMEDEAVRSRVQHKPKEDKLRLAQE 512
Query: 585 LSDLVSICKSVQYRDFEL-SMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIY 643
LSD+V CKSV + F Q ++EM SFSE A R+ E FV +N LSRIY
Sbjct: 513 LSDMVIYCKSVHFGGFSSPGTPGQAFYEMASFSENRALRLLQESGNGFVRHNVGHLSRIY 572
Query: 644 PSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDE 703
P+ R DSSN +P + WN GCQIVA+NFQTPGP MD++ G F NG CGYVL+P+ +RD
Sbjct: 573 PAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQGRFQDNGACGYVLKPAFLRDP 632
Query: 704 VSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSE 763
F+ P + L+I++ISGQ PK K ++DP V +EIHG+ D +
Sbjct: 633 NGTFNPRALAQGPWWARKRLNIRVISGQQLPKVNK--NKNSIVDPKVTVEIHGVSRDVAS 690
Query: 764 QRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIG-DEFIGQYTIPFECLQPG 822
++T + N NP +D F F+V +P+LA+IRF+V D D ++FIGQ TIP L+ G
Sbjct: 691 RQTAVITNNGFNPWWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIPLNSLKQG 750
Query: 823 YRHVPLRSFVGDIMEHVTLFVHIAI 847
YRHV L S GD TLFV I++
Sbjct: 751 YRHVHLMSKNGDQHPSATLFVKISL 775
>gi|25188201 phospholipase C, zeta 1 [Homo sapiens]
Length = 608
Score = 436 bits (1120), Expect = e-122
Identities = 240/602 (39%), Positives = 377/602 (62%), Gaps = 18/602 (2%)
Query: 252 DVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELC 311
D G I LE T L+++L+ ++ FK+ + K+ R+T EEF + +
Sbjct: 13 DFRGGKINLEKTQ-RLLEKLDIRCSYIHVKQIFKDNDRLKQG---RITIEEFRAIYRIIT 68
Query: 312 TRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDICLDIIRRYELSEEGRQKGF 371
R E+ + S+N++ L A++L FL EQ +++ I +II++YE EE R+
Sbjct: 69 HREEIIEIFNTYSENRKILLASNLAQFLTQEQYAAEMSKAIAFEIIQKYEPIEEVRKAHQ 128
Query: 372 LAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGY 431
++++GFT+Y+ S EC +F E +KV QDMT PL+ Y+I++SHNTYL+ DQ GP+D+ GY
Sbjct: 129 MSLEGFTRYMDSRECLLFKNECRKVYQDMTHPLNDYFISSSHNTYLVSDQLLGPSDLWGY 188
Query: 432 IRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCL 491
+ AL GCR +E+D DG+ NEP++ + +T+ + F++VI+ I+K+AF+ S+YP++L L
Sbjct: 189 VSALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSL 248
Query: 492 GNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSESYLPSPEKLKRMIIVKGKKLPSDPDVL 551
NHCS QQ+VMA ++ FG L ++ LPSPE LK I+VK KK+ + +
Sbjct: 249 ENHCSTAQQEVMADNLQATFGESLLSDMLDDFPDTLPSPEALKFKILVKNKKIGTLKETH 308
Query: 552 EGEVTD-----EDEEAEMSRRMSVDYNGEQK--QIRLCRELSDLVSICKSVQYRDFELSM 604
E + +D +D+E + + V ++K ++++ LSDLV K+ +++ F+ S
Sbjct: 309 ERKGSDKRGDNQDKETGVKKLPGVMLFKKKKTRKLKIALALSDLVIYTKAEKFKSFQHSR 368
Query: 605 KSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGC 664
Q + E S ET+A +++ +F+ + +KF++RIYP A R DSSN NPQ+FWN GC
Sbjct: 369 LYQQFNENNSIGETQARKLSKLRVHEFIFHTRKFITRIYPKATRADSSNFNPQEFWNIGC 428
Query: 665 QIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSPLALH 724
Q+VA+NFQTPG MDL G FL NGG GY+L+P +R+ SYF N I G+ P+ L
Sbjct: 429 QMVALNFQTPGLPMDLQNGKFLDNGGSGYILKPHFLRESKSYF--NPSNIKEGM-PITLT 485
Query: 725 IKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETFEF 784
I++ISG P + KGD + V IE+ G+P D +Q+T+ +++N+ +P ++ETF F
Sbjct: 486 IRLISGIQLPLTHSSSNKGDSL---VIIEVFGVPNDQMKQQTRVIKKNAFSPRWNETFTF 542
Query: 785 QVNLPELAMIRFVVLDDDYI-GDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFV 843
+++PELA+IRFVV I G+EF+GQYT+P C+ GYR +PL S +G+ +E +LFV
Sbjct: 543 IIHVPELALIRFVVEGQGLIAGNEFLGQYTLPLLCMNKGYRRIPLFSRMGESLEPASLFV 602
Query: 844 HI 845
++
Sbjct: 603 YV 604
>gi|19115964 phospholipase C delta 3 [Homo sapiens]
Length = 789
Score = 422 bits (1084), Expect = e-117
Identities = 279/790 (35%), Positives = 407/790 (51%), Gaps = 56/790 (7%)
Query: 79 IKDPSNQKCGGRKKTVSFSSMPSEKKISSAND-CISFMQAGCELKKVRPNSRIYNRFFTL 137
+ P GG K+ + + KK+ D + M G L+K+R + R + L
Sbjct: 32 LPSPPTPSDGGTKRP----GLRALKKMGLTEDEDVRAMLRGSRLRKIRSRTWHKERLYRL 87
Query: 138 DTDLQALRWEPSKKDLEKAKLD----ISAIKEIRLGKNTETFRNNG--LADQICEDCAFS 191
D ++ ++ + + +A + I+ +R G +E R G A C AF
Sbjct: 88 QEDGLSVWFQ---RRIPRAPSQHIFFVQHIEAVREGHQSEGLRRFGGAFAPARCLTIAFK 144
Query: 192 ILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAA 251
++LDL A +A+ A WV GL L +R LD M + W+ + A
Sbjct: 145 ----GRRKNLDLAAPTAEEAQRWVRGLTKLRAR----LDAMSQRERLDH--WIHSYLHRA 194
Query: 252 DVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELC 311
D + + M L++ +N + + L FKE S EEF L
Sbjct: 195 DSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECDHSNNDRLEGAEIEEFLR---RLL 251
Query: 312 TRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDICLDIIRRYELSEEGRQKGF 371
RPE+ + Q S L A +L+ FLE +QG T +I+ YEL+E +Q
Sbjct: 252 KRPELEEIFHQYSGEDRVLSAPELLEFLE-DQGEEGATLARAQQLIQTYELNETAKQHEL 310
Query: 372 LAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGY 431
+ +DGF YLLS E D V QDM QPL+HY+I++SHNTYL + Q GP+ Y
Sbjct: 311 MTLDGFMMYLLSPEGAALDNTHTCVFQDMNQPLAHYFISSSHNTYLTDSQIGGPSSTEAY 370
Query: 432 IRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCL 491
+RA GCR VELD +G EP++ + + +T+ + FR V++ + AF S YP+IL L
Sbjct: 371 VRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSL 430
Query: 492 GNHCSLPQQKVMAQQMKKVFGNKLYTEA-PLPSESYLPSPEKLKRMIIVKGKKLPSD--- 547
NHC L QQ MA+ + + G+ L T+A P+ LPSPE+LK ++VKGKKLP+
Sbjct: 431 ENHCGLEQQAAMARHLCTILGDMLVTQALDSPNPEELPSPEQLKGRVLVKGKKLPAARSE 490
Query: 548 -----PDVLEGEVTDEDEEAEM----SRRMSVDYNGEQKQIRLCRELSDLVSICKSVQYR 598
D E E DE+EE E+ RR++ KQI ELS L C + + R
Sbjct: 491 DGRALSDREEEEEDDEEEEEEVEAAAQRRLA-------KQI--SPELSALAVYCHATRLR 541
Query: 599 DFELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQD 658
+ + ++ S SE +A ++ E FV +N + L+R+YP +R++S+N +PQ+
Sbjct: 542 TLHPAPNAPQPCQVSSLSERKAKKLIREAGNSFVRHNARQLTRVYPLGLRMNSANYSPQE 601
Query: 659 FWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGV 718
WN GCQ+VA+NFQTPG MDL+ G FL NG CGYVL+P+ +R S F PG
Sbjct: 602 MWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPACLRQPDSTFDPE----YPGP 657
Query: 719 SPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIF 778
L I++++ Q PK A ++DP V IEIHG+PADC+ Q T V N NP +
Sbjct: 658 PRTTLSIQVLTAQQLPK-LNAEKPHSIVDPLVRIEIHGVPADCARQETDYVLNNGFNPRW 716
Query: 779 DETFEFQVNLPELAMIRFVVLDDDYIG-DEFIGQYTIPFECLQPGYRHVPLRSFVGDIME 837
+T +FQ+ PELA++RFVV D D ++F+GQ+T+P L+ GYRH+ L S G +
Sbjct: 717 GQTLQFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLSSLKQGYRHIHLLSKDGASLS 776
Query: 838 HVTLFVHIAI 847
TLF+ I I
Sbjct: 777 PATLFIQIRI 786
>gi|78499633 phospholipase C, eta 2 [Homo sapiens]
Length = 1416
Score = 350 bits (898), Expect = 4e-96
Identities = 202/499 (40%), Positives = 299/499 (59%), Gaps = 17/499 (3%)
Query: 111 CISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGK 170
C+ MQ G ++ K+R S+ RF+ LD +RW PS+K+ EKAK+ I +I+E+ G+
Sbjct: 45 CMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKN-EKAKISIDSIQEVSEGR 103
Query: 171 NTETFRN--NGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQP 228
+E F+ +G D +C FSI HG + ESLDLV+ S++VA WV+GLRYL++
Sbjct: 104 QSEVFQRYPDGSFDP---NCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDE 160
Query: 229 LDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQ 288
D + Q T R WLK F+ AD +G+G + ++L+ +LN L +++ F+E
Sbjct: 161 -DSLARRQRT-RDQWLKQTFDEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREAD 218
Query: 289 KSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHI 348
+ T EEFC + + TR ++Y L++ S +K++LDA L FL+ EQ + +
Sbjct: 219 TDDHQGTLGF--EEFCAFYKMMSTRRDLYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGV 276
Query: 349 TEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYY 408
T + C DII ++E E + KG L IDGFT Y S DIF+PE V QDMTQPLSHY+
Sbjct: 277 TLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYF 336
Query: 409 INASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSF 468
I +SHNTYL+ DQ + ++ Y L+ GCR VE+D DG D EPI+ + +T+ + F
Sbjct: 337 ITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILF 396
Query: 469 RSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKL-YTEAPLPSESYL 527
+ VIE INK+AF+ +EYP+IL + NHCS+ QQK MAQ + + G+KL + + L
Sbjct: 397 KDVIETINKYAFIKNEYPVILSIENHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATTL 456
Query: 528 PSPEKLKRMIIVKGKKLPSD--PDVLEGEVTDEDEEAEMS---RRMSVDYNGEQKQIRLC 582
PSP+ LK I+VKGKKLP++ D EGEV+DED E+ + ++ D + +K++
Sbjct: 457 PSPQMLKGKILVKGKKLPANISEDAEEGEVSDEDSADEIDDDCKLLNGDASTNRKRVENT 516
Query: 583 RELSDLVSICKSVQYRDFE 601
+ L S+ K + RD E
Sbjct: 517 AK-RKLDSLIKESKIRDCE 534
Score = 264 bits (675), Expect = 3e-70
Identities = 140/315 (44%), Positives = 200/315 (63%), Gaps = 16/315 (5%)
Query: 540 KGKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGEQKQIRLCRELSDLVSICKSVQYRD 599
KG KL V EG DE + S ++K ++L R LSDLV KSV D
Sbjct: 586 KGSKLKKAASVEEG-----DEGQDSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHD 640
Query: 600 FELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDF 659
E M++ + W++ SFSET+A +I + P ++ +N++ LSRIYPS+ R+DSSN NPQ F
Sbjct: 641 IE--MEAASSWQVSSFSETKAHQILQQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPF 698
Query: 660 WNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVS 719
WN GCQ+VA+N+Q+ G M+ L+ F NGGCGYVL+P M V F+ N++ LPG
Sbjct: 699 WNAGCQMVALNYQSEGRMLQLNRAKFSANGGCGYVLKPGCMCQGV--FNPNSEDPLPGQL 756
Query: 720 PLALHIKIISGQNFPKPKGACA--KGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPI 777
L ++IISGQ PKP+ + +G++IDP+V +EI G+P DCS ++T+ V N NP
Sbjct: 757 KKQLVLRIISGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPT 816
Query: 778 FDETFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIME 837
++ET F V++PE+A++RF+V D D IG +FIGQ T+ F + PGYRHV L ME
Sbjct: 817 WEETLVFMVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEG-----ME 871
Query: 838 HVTLFVHIAITNRSG 852
++FVH+A+++ SG
Sbjct: 872 EASIFVHVAVSDISG 886
>gi|195972873 phospholipase C eta 1 isoform c [Homo sapiens]
Length = 1002
Score = 339 bits (869), Expect = 1e-92
Identities = 196/497 (39%), Positives = 293/497 (58%), Gaps = 12/497 (2%)
Query: 111 CISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGK 170
C+S MQ+G ++ K++ ++ R F LD LRW PS+K EKAK+ I +I ++ G+
Sbjct: 18 CMSVMQSGTQMIKLKRGTKGLVRLFYLDEHRTRLRWRPSRKS-EKAKILIDSIYKVTEGR 76
Query: 171 NTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLD 230
+E F + C F+I HG + ESLDL+ ++ + A W++GL+YL++ D
Sbjct: 77 QSEIFHRQAEGN-FDPSCCFTIYHGNHMESLDLITSNPEEARTWITGLKYLMAGISDE-D 134
Query: 231 FMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKS 290
+ Q T W+K FE AD +G+G++ + +L+ +LN L K+R F+E
Sbjct: 135 SLAKRQRT-HDQWVKQTFEEADKNGDGLLNIEEIHQLMHKLNVNLPRRKVRQMFQEADTD 193
Query: 291 KEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITE 350
+ + T +T EEFC + + R ++Y LL+ S K++L +L FL+ EQ + ++T
Sbjct: 194 ENQGT--LTFEEFCVFYKMMSLRRDLYLLLLSYSDKKDHLTVEELAQFLKVEQKMNNVTT 251
Query: 351 DICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYIN 410
D CLDII+++E+SEE + K L I+GFT ++ S CDIF+P +V QDM QPL +YYI
Sbjct: 252 DYCLDIIKKFEVSEENKVKNVLGIEGFTNFMRSPACDIFNPLHHEVYQDMDQPLCNYYIA 311
Query: 411 ASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRS 470
+SHNTYL DQ + ++ Y R L+ GCR VE+D DG D EP++ + +T+ + FR
Sbjct: 312 SSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDGEPVVHHGYTLTSKILFRD 371
Query: 471 VIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSE-SYLPS 529
V+E INK AFV +E+P+IL + NHCS+ QQ+ +AQ +K +FG+KL + E LPS
Sbjct: 372 VVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKGIFGDKLDLSSVDTGECKQLPS 431
Query: 530 PEKLKRMIIVKGKKLP--SDPDVLEGEVTDED--EEAEMSRRMSVDY-NGEQKQIRLCRE 584
P+ LK I+VKGKKLP D EGEV+DED +E E + + Y NG +
Sbjct: 432 PQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEIEDECKFKLHYSNGTTEHQVESFI 491
Query: 585 LSDLVSICKSVQYRDFE 601
L S+ K Q RD E
Sbjct: 492 RKKLESLLKESQIRDKE 508
Score = 233 bits (594), Expect = 7e-61
Identities = 129/304 (42%), Positives = 182/304 (59%), Gaps = 18/304 (5%)
Query: 556 TDEDEEAEMSRRMS----VDYNGEQKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWE 611
TD++E+ + S +K ++LCRELSDLV SV +D + N
Sbjct: 568 TDDEEDTQQSTGKEGGQLYRLGRRRKTMKLCRELSDLVVYTNSVAAQDIVDDGTTGN--- 624
Query: 612 MCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNF 671
+ SFSET A ++ + E F+ YN+K L+RIYPSA RIDSSN NP +WN GCQ+VA+N+
Sbjct: 625 VLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNY 684
Query: 672 QTPGPMMDLHTGWFLQNGGCGYVLRPSIM-RDEVSYFSANTKGILPGVSPLALHIKIISG 730
Q+ G MM L+ F NG CGYVL+P M + + FS + LP L +K+ISG
Sbjct: 685 QSEGRMMQLNRAKFKANGNCGYVLKPQQMCKGTFNPFSGDP---LPANPKKQLILKVISG 741
Query: 731 QNFPKPKGAC--AKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNL 788
Q PKP + +G++IDP+V +EI G+P DC + +T+ V N NP+++ET F V++
Sbjct: 742 QQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHM 801
Query: 789 PELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAIT 848
PE+A++RF+V D D IG +F+GQ T+ F L PGYRHV L + ++FVHI I
Sbjct: 802 PEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYRHVYLEG-----LTEASIFVHITIN 856
Query: 849 NRSG 852
G
Sbjct: 857 EIYG 860
>gi|195972871 phospholipase C eta 1 isoform a [Homo sapiens]
Length = 1693
Score = 339 bits (869), Expect = 1e-92
Identities = 196/497 (39%), Positives = 293/497 (58%), Gaps = 12/497 (2%)
Query: 111 CISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGK 170
C+S MQ+G ++ K++ ++ R F LD LRW PS+K EKAK+ I +I ++ G+
Sbjct: 18 CMSVMQSGTQMIKLKRGTKGLVRLFYLDEHRTRLRWRPSRKS-EKAKILIDSIYKVTEGR 76
Query: 171 NTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLD 230
+E F + C F+I HG + ESLDL+ ++ + A W++GL+YL++ D
Sbjct: 77 QSEIFHRQAEGN-FDPSCCFTIYHGNHMESLDLITSNPEEARTWITGLKYLMAGISDE-D 134
Query: 231 FMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKS 290
+ Q T W+K FE AD +G+G++ + +L+ +LN L K+R F+E
Sbjct: 135 SLAKRQRT-HDQWVKQTFEEADKNGDGLLNIEEIHQLMHKLNVNLPRRKVRQMFQEADTD 193
Query: 291 KEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITE 350
+ + T +T EEFC + + R ++Y LL+ S K++L +L FL+ EQ + ++T
Sbjct: 194 ENQGT--LTFEEFCVFYKMMSLRRDLYLLLLSYSDKKDHLTVEELAQFLKVEQKMNNVTT 251
Query: 351 DICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYIN 410
D CLDII+++E+SEE + K L I+GFT ++ S CDIF+P +V QDM QPL +YYI
Sbjct: 252 DYCLDIIKKFEVSEENKVKNVLGIEGFTNFMRSPACDIFNPLHHEVYQDMDQPLCNYYIA 311
Query: 411 ASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRS 470
+SHNTYL DQ + ++ Y R L+ GCR VE+D DG D EP++ + +T+ + FR
Sbjct: 312 SSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDGEPVVHHGYTLTSKILFRD 371
Query: 471 VIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSE-SYLPS 529
V+E INK AFV +E+P+IL + NHCS+ QQ+ +AQ +K +FG+KL + E LPS
Sbjct: 372 VVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKGIFGDKLDLSSVDTGECKQLPS 431
Query: 530 PEKLKRMIIVKGKKLP--SDPDVLEGEVTDED--EEAEMSRRMSVDY-NGEQKQIRLCRE 584
P+ LK I+VKGKKLP D EGEV+DED +E E + + Y NG +
Sbjct: 432 PQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEIEDECKFKLHYSNGTTEHQVESFI 491
Query: 585 LSDLVSICKSVQYRDFE 601
L S+ K Q RD E
Sbjct: 492 RKKLESLLKESQIRDKE 508
Score = 233 bits (594), Expect = 7e-61
Identities = 129/304 (42%), Positives = 182/304 (59%), Gaps = 18/304 (5%)
Query: 556 TDEDEEAEMSRRMS----VDYNGEQKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWE 611
TD++E+ + S +K ++LCRELSDLV SV +D + N
Sbjct: 568 TDDEEDTQQSTGKEGGQLYRLGRRRKTMKLCRELSDLVVYTNSVAAQDIVDDGTTGN--- 624
Query: 612 MCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNF 671
+ SFSET A ++ + E F+ YN+K L+RIYPSA RIDSSN NP +WN GCQ+VA+N+
Sbjct: 625 VLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNY 684
Query: 672 QTPGPMMDLHTGWFLQNGGCGYVLRPSIM-RDEVSYFSANTKGILPGVSPLALHIKIISG 730
Q+ G MM L+ F NG CGYVL+P M + + FS + LP L +K+ISG
Sbjct: 685 QSEGRMMQLNRAKFKANGNCGYVLKPQQMCKGTFNPFSGDP---LPANPKKQLILKVISG 741
Query: 731 QNFPKPKGAC--AKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNL 788
Q PKP + +G++IDP+V +EI G+P DC + +T+ V N NP+++ET F V++
Sbjct: 742 QQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHM 801
Query: 789 PELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAIT 848
PE+A++RF+V D D IG +F+GQ T+ F L PGYRHV L + ++FVHI I
Sbjct: 802 PEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYRHVYLEG-----LTEASIFVHITIN 856
Query: 849 NRSG 852
G
Sbjct: 857 EIYG 860
>gi|57863298 phospholipase C eta 1 isoform b [Homo sapiens]
Length = 1655
Score = 335 bits (860), Expect = 1e-91
Identities = 195/496 (39%), Positives = 292/496 (58%), Gaps = 12/496 (2%)
Query: 112 ISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKN 171
+S MQ+G ++ K++ ++ R F LD LRW PS+K EKAK+ I +I ++ G+
Sbjct: 1 MSVMQSGTQMIKLKRGTKGLVRLFYLDEHRTRLRWRPSRKS-EKAKILIDSIYKVTEGRQ 59
Query: 172 TETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDF 231
+E F + C F+I HG + ESLDL+ ++ + A W++GL+YL++ D
Sbjct: 60 SEIFHRQAEGN-FDPSCCFTIYHGNHMESLDLITSNPEEARTWITGLKYLMAGISDE-DS 117
Query: 232 MEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSK 291
+ Q T W+K FE AD +G+G++ + +L+ +LN L K+R F+E +
Sbjct: 118 LAKRQRT-HDQWVKQTFEEADKNGDGLLNIEEIHQLMHKLNVNLPRRKVRQMFQEADTDE 176
Query: 292 EKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITED 351
+ T +T EEFC + + R ++Y LL+ S K++L +L FL+ EQ + ++T D
Sbjct: 177 NQGT--LTFEEFCVFYKMMSLRRDLYLLLLSYSDKKDHLTVEELAQFLKVEQKMNNVTTD 234
Query: 352 ICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINA 411
CLDII+++E+SEE + K L I+GFT ++ S CDIF+P +V QDM QPL +YYI +
Sbjct: 235 YCLDIIKKFEVSEENKVKNVLGIEGFTNFMRSPACDIFNPLHHEVYQDMDQPLCNYYIAS 294
Query: 412 SHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSV 471
SHNTYL DQ + ++ Y R L+ GCR VE+D DG D EP++ + +T+ + FR V
Sbjct: 295 SHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDGEPVVHHGYTLTSKILFRDV 354
Query: 472 IEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSE-SYLPSP 530
+E INK AFV +E+P+IL + NHCS+ QQ+ +AQ +K +FG+KL + E LPSP
Sbjct: 355 VETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKGIFGDKLDLSSVDTGECKQLPSP 414
Query: 531 EKLKRMIIVKGKKLP--SDPDVLEGEVTDED--EEAEMSRRMSVDY-NGEQKQIRLCREL 585
+ LK I+VKGKKLP D EGEV+DED +E E + + Y NG +
Sbjct: 415 QSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEIEDECKFKLHYSNGTTEHQVESFIR 474
Query: 586 SDLVSICKSVQYRDFE 601
L S+ K Q RD E
Sbjct: 475 KKLESLLKESQIRDKE 490
Score = 234 bits (597), Expect = 3e-61
Identities = 135/329 (41%), Positives = 190/329 (57%), Gaps = 19/329 (5%)
Query: 556 TDEDEEAEMSRRMS----VDYNGEQKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWE 611
TD++E+ + S +K ++LCRELSDLV SV +D + N
Sbjct: 550 TDDEEDTQQSTGKEGGQLYRLGRRRKTMKLCRELSDLVVYTNSVAAQDIVDDGTTGN--- 606
Query: 612 MCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNF 671
+ SFSET A ++ + E F+ YN+K L+RIYPSA RIDSSN NP +WN GCQ+VA+N+
Sbjct: 607 VLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNY 666
Query: 672 QTPGPMMDLHTGWFLQNGGCGYVLRPSIM-RDEVSYFSANTKGILPGVSPLALHIKIISG 730
Q+ G MM L+ F NG CGYVL+P M + + FS + LP L +K+ISG
Sbjct: 667 QSEGRMMQLNRAKFKANGNCGYVLKPQQMCKGTFNPFSGDP---LPANPKKQLILKVISG 723
Query: 731 QNFPKPKGAC--AKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNL 788
Q PKP + +G++IDP+V +EI G+P DC + +T+ V N NP+++ET F V++
Sbjct: 724 QQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHM 783
Query: 789 PELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAIT 848
PE+A++RF+V D D IG +F+GQ T+ F L PGYRHV L + ++FVHI I
Sbjct: 784 PEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYRHVYLEG-----LTEASIFVHITI- 837
Query: 849 NRSGGGKAQKRSLSVRMGKKVREYTMLRN 877
N G Q + L K R + N
Sbjct: 838 NEIYGKNRQLQGLKGLFNKNPRHSSSENN 866
>gi|12083581 phosphoinositide-specific phospholipase C beta 1
isoform a [Homo sapiens]
Length = 1216
Score = 332 bits (850), Expect = 2e-90
Identities = 238/775 (30%), Positives = 384/775 (49%), Gaps = 86/775 (11%)
Query: 137 LDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQI-------CEDCA 189
L TD Q + + ++ E LD+S +K+ R G++ + ++ L + + E
Sbjct: 43 LRTDPQGFFFYWTDQNKETELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRM 102
Query: 190 FSILHGE---NYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKT 246
++++G N L+LVA +VA W + + L + + + N + F+
Sbjct: 103 ITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLAT------NLLAQNMSRDAFLEKAY 156
Query: 247 VFEAADVDGNG-IMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTR--VTEEEF 303
V G I L++ + + + K + L+ + S+ + T E +
Sbjct: 157 TKLKLQVTPEGRIPLKN----IYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVY 212
Query: 304 CEAFCELCTRPEVYFLLVQI-SKNKEYLDANDLMLFLEAEQGVTHITEDICLDI------ 356
LC RPE+ + + +K+K YL + +M F+ +Q + E + +
Sbjct: 213 RVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQ 272
Query: 357 --IRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHN 414
I +YE + +KG +++DGF +YL E + PE+ + +DM+QPLSHY+IN+SHN
Sbjct: 273 VLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHN 332
Query: 415 TYLIEDQFRGPADINGYIRALKMGCRSVELDVSDG--SDNEPILCNRNNMTTHVSFRSVI 472
TYL Q G + + Y + L GCR VELD G ++ EP++ + MTT +SF+ VI
Sbjct: 333 TYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVI 392
Query: 473 EVINKFAFVASEYPLILCLGNHCSLPQQKV-MAQQMKKVFGNKLYTEA----PLPSESYL 527
E I + AF S +P++L NH P+Q+ MA+ + +FG+ L E PL S L
Sbjct: 393 EAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPL 452
Query: 528 PSPEKLKRMIIVKGKKL-----------------------------PSDPDVLEGEV-TD 557
PSP L I+VK KK PS P E + +D
Sbjct: 453 PSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEADTESD 512
Query: 558 EDEEAEMSRRMSVDYNGEQKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSE 617
+D++ + ++ S+D + E+S+LV+ + V++ FE+S K +EM SF E
Sbjct: 513 DDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVE 572
Query: 618 TEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPM 677
T+ + P +FV YNK LSRIYP R+DSSN PQ FWN GCQ+VA+NFQT
Sbjct: 573 TKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLA 632
Query: 678 MDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPK 737
M ++ G + NG GY L+P MR +F T+GI+ G+ L +KIISGQ K
Sbjct: 633 MQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKK 692
Query: 738 GACAKGDVIDPYVCIEIHGIPADCSEQ--RTKTVQQNSDNPIFDE---TFEFQVNLPELA 792
+ YV +++ G+P D + +TKT Q N+ NP+++E F+ +V LP LA
Sbjct: 693 --------VGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFK-KVVLPTLA 743
Query: 793 MIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAI 847
+R V ++ G +FIG +P + ++PGY ++ LR+ + +FV+I +
Sbjct: 744 CLRIAVYEE---GGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEV 795
>gi|33356544 phosphoinositide-specific phospholipase C beta 1
isoform b [Homo sapiens]
Length = 1173
Score = 332 bits (850), Expect = 2e-90
Identities = 238/775 (30%), Positives = 384/775 (49%), Gaps = 86/775 (11%)
Query: 137 LDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQI-------CEDCA 189
L TD Q + + ++ E LD+S +K+ R G++ + ++ L + + E
Sbjct: 43 LRTDPQGFFFYWTDQNKETELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRM 102
Query: 190 FSILHGE---NYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKT 246
++++G N L+LVA +VA W + + L + + + N + F+
Sbjct: 103 ITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLAT------NLLAQNMSRDAFLEKAY 156
Query: 247 VFEAADVDGNG-IMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTR--VTEEEF 303
V G I L++ + + + K + L+ + S+ + T E +
Sbjct: 157 TKLKLQVTPEGRIPLKN----IYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVY 212
Query: 304 CEAFCELCTRPEVYFLLVQI-SKNKEYLDANDLMLFLEAEQGVTHITEDICLDI------ 356
LC RPE+ + + +K+K YL + +M F+ +Q + E + +
Sbjct: 213 RVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQ 272
Query: 357 --IRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHN 414
I +YE + +KG +++DGF +YL E + PE+ + +DM+QPLSHY+IN+SHN
Sbjct: 273 VLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHN 332
Query: 415 TYLIEDQFRGPADINGYIRALKMGCRSVELDVSDG--SDNEPILCNRNNMTTHVSFRSVI 472
TYL Q G + + Y + L GCR VELD G ++ EP++ + MTT +SF+ VI
Sbjct: 333 TYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVI 392
Query: 473 EVINKFAFVASEYPLILCLGNHCSLPQQKV-MAQQMKKVFGNKLYTEA----PLPSESYL 527
E I + AF S +P++L NH P+Q+ MA+ + +FG+ L E PL S L
Sbjct: 393 EAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPL 452
Query: 528 PSPEKLKRMIIVKGKKL-----------------------------PSDPDVLEGEV-TD 557
PSP L I+VK KK PS P E + +D
Sbjct: 453 PSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEADTESD 512
Query: 558 EDEEAEMSRRMSVDYNGEQKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSE 617
+D++ + ++ S+D + E+S+LV+ + V++ FE+S K +EM SF E
Sbjct: 513 DDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVE 572
Query: 618 TEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPM 677
T+ + P +FV YNK LSRIYP R+DSSN PQ FWN GCQ+VA+NFQT
Sbjct: 573 TKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLA 632
Query: 678 MDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPK 737
M ++ G + NG GY L+P MR +F T+GI+ G+ L +KIISGQ K
Sbjct: 633 MQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKK 692
Query: 738 GACAKGDVIDPYVCIEIHGIPADCSEQ--RTKTVQQNSDNPIFDE---TFEFQVNLPELA 792
+ YV +++ G+P D + +TKT Q N+ NP+++E F+ +V LP LA
Sbjct: 693 --------VGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFK-KVVLPTLA 743
Query: 793 MIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAI 847
+R V ++ G +FIG +P + ++PGY ++ LR+ + +FV+I +
Sbjct: 744 CLRIAVYEE---GGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEV 795
>gi|33469933 phospholipase C beta 4 isoform a [Homo sapiens]
Length = 1194
Score = 328 bits (842), Expect = 1e-89
Identities = 251/831 (30%), Positives = 397/831 (47%), Gaps = 121/831 (14%)
Query: 113 SFMQAGCELKKVRPNSRIY--NRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLG- 169
SF+Q G + S ++ N F +D L W K E L+ S I IR G
Sbjct: 15 SFLQEGTVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGK--EGQVLECSLINSIRSGA 72
Query: 170 -----KNTETFRNNGLADQICEDCAFSILHGENYESLD---LVANSADVANIWVSGLRYL 221
K G ++ E + G + ++ +VA + +V WV GLR +
Sbjct: 73 IPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSI 132
Query: 222 V----SRSKQPLDFMEGNQNTPRFMWLKTVFEA---ADVDGNGIMLEDTSVELIKQLNPT 274
+ + + P+ ++ + W+K F + I S + K +
Sbjct: 133 IHNFRANNVSPMTCLKKH-------WMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQA 185
Query: 275 LKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNK-EYLDAN 333
LKE + K+ E T + E+F E ++C R ++ L +I+ +K +YL +
Sbjct: 186 LKELGL-----PSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD 240
Query: 334 DLMLFLEAEQGVTHITEDI--------CLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSE 385
L+ FL Q + E + + II YE E+ ++KG ++ DGF +YL+S E
Sbjct: 241 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE 300
Query: 386 CDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELD 445
++ ++ Q+M PL+HY+I++SHNTYL QF G + + Y + L GCR VELD
Sbjct: 301 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD 360
Query: 446 VSD--GSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVM 503
D G D EPI+ + M T + F+ VI+ I + AFV SEYP+IL NHCS QQ M
Sbjct: 361 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM 420
Query: 504 AQQMKKVFGNKLYTEA----PLPSESYLPSPEKLKRMIIVKGKKL--------------- 544
++ + +FG+ L +A PL LPSP LKR I++K K+L
Sbjct: 421 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM 480
Query: 545 ------PSDPDVLEG------EVTDEDEEA----EMSRRMSVDYNGEQKQI--------- 579
S ++LE E D++EEA + +S D G ++ +
Sbjct: 481 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV 540
Query: 580 -------------------RLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEA 620
+ LS +++ + V+++ F ++ + ++ M SF+E+
Sbjct: 541 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG 600
Query: 621 SRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDL 680
+ +FVNYNK+ +SRIYP R+DSSN PQ FWN GCQ+V++N+QTP M L
Sbjct: 601 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL 660
Query: 681 HTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGAC 740
+ G F NG CGY+L+P MR F ++ + GV +++ISGQ K
Sbjct: 661 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKK--- 717
Query: 741 AKGDVIDPYVCIEIHGIPADC--SEQRTKTVQQNSDNPIF-DETFEF-QVNLPELAMIRF 796
I YV ++++G+P D E RT+ V N NP++ +E+F F +V LP+LA++R
Sbjct: 718 -----IGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRI 772
Query: 797 VVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAI 847
V DD+ ++ IGQ +P + LQ GYRH+ LR+ + T+F +I +
Sbjct: 773 AVYDDN---NKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVL 820
>gi|33469939 phospholipase C beta 4 isoform b [Homo sapiens]
Length = 1175
Score = 328 bits (842), Expect = 1e-89
Identities = 251/831 (30%), Positives = 397/831 (47%), Gaps = 121/831 (14%)
Query: 113 SFMQAGCELKKVRPNSRIY--NRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLG- 169
SF+Q G + S ++ N F +D L W K E L+ S I IR G
Sbjct: 15 SFLQEGTVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGK--EGQVLECSLINSIRSGA 72
Query: 170 -----KNTETFRNNGLADQICEDCAFSILHGENYESLD---LVANSADVANIWVSGLRYL 221
K G ++ E + G + ++ +VA + +V WV GLR +
Sbjct: 73 IPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSI 132
Query: 222 V----SRSKQPLDFMEGNQNTPRFMWLKTVFEA---ADVDGNGIMLEDTSVELIKQLNPT 274
+ + + P+ ++ + W+K F + I S + K +
Sbjct: 133 IHNFRANNVSPMTCLKKH-------WMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQA 185
Query: 275 LKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNK-EYLDAN 333
LKE + K+ E T + E+F E ++C R ++ L +I+ +K +YL +
Sbjct: 186 LKELGL-----PSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD 240
Query: 334 DLMLFLEAEQGVTHITEDI--------CLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSE 385
L+ FL Q + E + + II YE E+ ++KG ++ DGF +YL+S E
Sbjct: 241 QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDE 300
Query: 386 CDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELD 445
++ ++ Q+M PL+HY+I++SHNTYL QF G + + Y + L GCR VELD
Sbjct: 301 NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD 360
Query: 446 VSD--GSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVM 503
D G D EPI+ + M T + F+ VI+ I + AFV SEYP+IL NHCS QQ M
Sbjct: 361 CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM 420
Query: 504 AQQMKKVFGNKLYTEA----PLPSESYLPSPEKLKRMIIVKGKKL--------------- 544
++ + +FG+ L +A PL LPSP LKR I++K K+L
Sbjct: 421 SKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSM 480
Query: 545 ------PSDPDVLEG------EVTDEDEEA----EMSRRMSVDYNGEQKQI--------- 579
S ++LE E D++EEA + +S D G ++ +
Sbjct: 481 MEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLV 540
Query: 580 -------------------RLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEA 620
+ LS +++ + V+++ F ++ + ++ M SF+E+
Sbjct: 541 TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVG 600
Query: 621 SRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDL 680
+ +FVNYNK+ +SRIYP R+DSSN PQ FWN GCQ+V++N+QTP M L
Sbjct: 601 LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL 660
Query: 681 HTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGAC 740
+ G F NG CGY+L+P MR F ++ + GV +++ISGQ K
Sbjct: 661 NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKK--- 717
Query: 741 AKGDVIDPYVCIEIHGIPADC--SEQRTKTVQQNSDNPIF-DETFEF-QVNLPELAMIRF 796
I YV ++++G+P D E RT+ V N NP++ +E+F F +V LP+LA++R
Sbjct: 718 -----IGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRI 772
Query: 797 VVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAI 847
V DD+ ++ IGQ +P + LQ GYRH+ LR+ + T+F +I +
Sbjct: 773 AVYDDN---NKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVL 820
>gi|95147333 phospholipase C, beta 2 [Homo sapiens]
Length = 1185
Score = 279 bits (714), Expect = 9e-75
Identities = 238/807 (29%), Positives = 368/807 (45%), Gaps = 106/807 (13%)
Query: 144 LRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQICEDC--------AFSILHG 195
L W K++E LDI++I++ R GK + ++ L D D +++ G
Sbjct: 47 LYWTYQSKEMEF--LDITSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSG 104
Query: 196 ENYESL---DLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAAD 252
+ L + V+ +V W + LV K PL N R +L +
Sbjct: 105 PDMVDLTFHNFVSYKENVGKAWAEDVLALV---KHPL-----TANASRSTFLDKILVKLK 156
Query: 253 VDGNGIMLEDTSVELIKQLNPT-LKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEA----- 306
+ N V+ Q+ P K + L + K K + E+F E
Sbjct: 157 MQLNSE--GKIPVKNFFQMFPADRKRVEAALSACHLPKGKNDA---INPEDFPEPVYKSF 211
Query: 307 FCELCTRPEVYFLLVQI-SKNKEYLDANDLMLFLEAEQGVTHITE--------DICLDII 357
LC RPE+ + +K K Y+ L F+ +Q + + D +I
Sbjct: 212 LMSLCPRPEIDEIFTSYHAKAKPYMTKEHLTKFINQKQRDSRLNSLLFPPARPDQVQGLI 271
Query: 358 RRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHNTYL 417
+YE S Q+G L+ +G +L E + ++ + DMTQPL+HY+IN+SHNTYL
Sbjct: 272 DKYEPSGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYL 331
Query: 418 IEDQFRGPADINGYIRALKMGCRSVELDVSDGS--DNEPILCNRNNMTTHVSFRSVIEVI 475
QF G + Y + L GCR VELD G D EPI+ + MTT + F+ IE I
Sbjct: 332 TAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAI 391
Query: 476 NKFAFVASEYPLILCLGNHCSLPQQKV-MAQQMKKVFGNKLYTEA----PLPSESYLPSP 530
+ AF S YP+IL NH P+Q+ MA+ + +FG+ L TE PL LPSP
Sbjct: 392 AESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSP 451
Query: 531 EKLKRMIIVKGKKL---------------------PSDP-------------DVLEGEVT 556
E L+ I++K KK PS P ++ E EV
Sbjct: 452 EDLRGKILIKNKKNQFSGPTSSSKDTGGEAEGSSPPSAPAGEGTVWAGEEGTELEEEEVE 511
Query: 557 DEDEEA------EMSRRMSVDYNGEQKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYW 610
+E+EE E ++M D ++ E+S LV+ + ++ FE S + +
Sbjct: 512 EEEEEESGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSY 571
Query: 611 EMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMN 670
+ SF+E +A + ++ FV+YNK+ +SRIYP R+DSSN PQ FWN GCQ+VA+N
Sbjct: 572 VISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALN 631
Query: 671 FQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISG 730
FQT M + F NG GY+L+ MR F+ + + V L I +ISG
Sbjct: 632 FQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISG 691
Query: 731 QNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQ-RTK-TVQQNSDNPIF-DETFEFQ-V 786
Q + + YV +E+ G+P D + RTK + NS NP++ +E F F+ +
Sbjct: 692 QFLSERS--------VRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKI 743
Query: 787 NLPELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIA 846
+PELA +R V+++ G++F+G IP L GY H+ L S + LF+ +
Sbjct: 744 LMPELASLRVAVMEE---GNKFLGHRIIPINALNSGYHHLCLHSESNMPLTMPALFIFLE 800
Query: 847 ITNRSGGGKAQKRSLSVRMGKKVREYT 873
+ + G A L+V + ++ ++
Sbjct: 801 MKDYIPGAWA---DLTVALANPIKFFS 824
>gi|117320537 phospholipase C, gamma 2 [Homo sapiens]
Length = 1265
Score = 199 bits (507), Expect = 9e-51
Identities = 154/457 (33%), Positives = 232/457 (50%), Gaps = 41/457 (8%)
Query: 140 DLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENY- 198
+ + + W + +E LDI IKEIR GKN++ F Q EDC F+IL+G +
Sbjct: 48 ETRQVAWSKTADKIE-GFLDIMEIKEIRPGKNSKDFERAKAVRQK-EDCCFTILYGTQFV 105
Query: 199 -ESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPRFM--WL-KTVFEAADVD 254
+L L A+S + A W+SGL+ L + N +TP + WL K ++
Sbjct: 106 LSTLSLAADSKEDAVNWLSGLKILHQEAM--------NASTPTIIESWLRKQIYSVDQTR 157
Query: 255 GNGIMLEDTSVELIKQLNPTLKEAK-IRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTR 313
N I L + ++ +N + AK ++ KF EI K++L+ E+F + +L
Sbjct: 158 RNSISLRELKT-ILPLINFKVSSAKFLKDKFVEIGAHKDELSF----EQFHLFYKKLMFE 212
Query: 314 PEVYFL-------LVQISKNKEYLDAN-----DLMLFLEAEQGVTHITEDICLDIIRRYE 361
+ L V I N + DA+ D FL EQ H +D+ R +
Sbjct: 213 QQKSILDEFKKDSSVFILGNTDRPDASAVYLHDFQRFLIHEQQ-EHWAQDLNKVRERMTK 271
Query: 362 LSEEGRQKG---FLAIDGFTQYLLSSECDIFDPEQKKV-AQDMTQPLSHYYINASHNTYL 417
++ ++ FL +D F YL S E I+D + V QDM PLSHY+I++SHNTYL
Sbjct: 272 FIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYL 331
Query: 418 IEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIEVINK 477
DQ R + YIR L+MGCR +ELD DG D +P++ + TT + F V++ I
Sbjct: 332 TGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKD 391
Query: 478 FAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSESYLPSPEKLKRMI 537
AFV S +P+IL + HCS+ QQ+ MA+ K+VFG+ L T+ S LPSP +L+ I
Sbjct: 392 HAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVFGDLLLTKPTEASADQLPSPSQLREKI 451
Query: 538 IVKGKKLPSDPDV---LEGEVTDEDEEAEMSRRMSVD 571
I+K KKL DV +E + + ++ E+ S+D
Sbjct: 452 IIKHKKLGPRGDVDVNMEDKKDEHKQQGELYMWDSID 488
Score = 145 bits (367), Expect = 2e-34
Identities = 106/333 (31%), Positives = 164/333 (49%), Gaps = 31/333 (9%)
Query: 528 PSPEKLKRMIIVKGKKLPSDPDVLEGEVTDEDEEA--------EMSRRMSVDYNGE---Q 576
P + K + + K DP V TD EE E++ ++ N +
Sbjct: 864 PQGKNQKSFVFILEPKQQGDPPV--EFATDRVEELFEWFQSIREITWKIDTKENNMKYWE 921
Query: 577 KQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYNK 636
K + ELSDLV CK L ++ ++ E+ SF ET+A I + P D + YN+
Sbjct: 922 KNQSIAIELSDLVVYCKPTSKTKDNL--ENPDFREIRSFVETKADSIIRQKPVDLLKYNQ 979
Query: 637 KFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLR 696
K L+R+YP R+DSSN +P W CG Q+VA+NFQT M ++ F NG GYVL+
Sbjct: 980 KGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQ 1039
Query: 697 PSIMRDEV--SYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEI 754
P MR E + + IL + L +K++ ++ PK + P+V +EI
Sbjct: 1040 PESMRTEKYDPMPPESQRKIL-----MTLTVKVLGARHLPK-----LGRSIACPFVEVEI 1089
Query: 755 HGIPADCSEQRTKTVQQNSDNPIFDETFE---FQVNLPELAMIRFVVLDDDYIGD-EFIG 810
G D ++ +T V N +PI+ T E F++ P LA +RFVV ++D D F+
Sbjct: 1090 CGAEYDNNKFKTTVVNDNGLSPIWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLA 1149
Query: 811 QYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFV 843
T P + ++ G+R VPL++ + +E +L V
Sbjct: 1150 HATYPIKAVKSGFRSVPLKNGYSEDIELASLLV 1182
>gi|33598948 phospholipase C, gamma 1 isoform a [Homo sapiens]
Length = 1291
Score = 186 bits (472), Expect = 1e-46
Identities = 109/299 (36%), Positives = 172/299 (57%), Gaps = 14/299 (4%)
Query: 576 QKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYP-EDFVNY 634
+++ ++ ELS+LV C+ V + + ++ + Y +M SF ET+A + N+ + F+ Y
Sbjct: 944 ERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQY 1003
Query: 635 NKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYV 694
N+ LSRIYP R+DSSN +P W CG Q+VA+NFQTP M ++ F+ CGYV
Sbjct: 1004 NRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYV 1063
Query: 695 LRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEI 754
L+PS MRDE F K L G+ P A+ I+++ ++ PK +G ++ P+V IE+
Sbjct: 1064 LQPSTMRDEA--FDPFDKSSLRGLEPCAISIEVLGARHLPKN----GRG-IVCPFVEIEV 1116
Query: 755 HGIPADCSEQRTKTVQQNSDNPIFD-ETFEFQVNLPELAMIRFVVLDDDYIGDE-FIGQY 812
G D ++Q+T+ V N NP++ + F FQ++ PE A +RFVV ++D D+ F+ Q
Sbjct: 1117 AGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQA 1176
Query: 813 TIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKVRE 871
T P + L+ GYR VPL++ + +E +L + I I K + LS G +RE
Sbjct: 1177 TFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIF----PAKQENGDLSPFSGTSLRE 1231
Score = 185 bits (469), Expect = 2e-46
Identities = 137/448 (30%), Positives = 217/448 (48%), Gaps = 50/448 (11%)
Query: 125 RPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQI 184
+ + R + F + + + + W +E A +DI IKEIR GK + F D+
Sbjct: 41 KKSQRPERKTFQVKLETRQITWSRGADKIEGA-IDIREIKEIRPGKTSRDF------DRY 93
Query: 185 CEDCAFS--------ILHGENY--ESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEG 234
ED AF IL+G + ++L L A S D N+W+ GL +L+ + Q ++
Sbjct: 94 QEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQI 153
Query: 235 NQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLN---PTLKEAKIRL--------- 282
+ WL+ F + D + + ++ Q+N P ++ + RL
Sbjct: 154 ER------WLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGD 207
Query: 283 ----KFKEIQKSKEKLTTRVTEEEFCEAFC-ELCTRPEVYFLLVQISKNKEYLDANDLML 337
+F ++ +S + + F EA RPE+ V + + +++L L
Sbjct: 208 ITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPEL--CRVSLPEFQQFLLDYQGEL 265
Query: 338 FLEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVA 397
+ V D +R E + + +D F +L S E +++ + V
Sbjct: 266 WAVDRLQVQEFMLSFLRDPLREIE-------EPYFFLDEFVTFLFSKENSVWNSQLDAVC 318
Query: 398 QD-MTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPIL 456
D M PLSHY+I++SHNTYL DQF + + Y R L+MGCR +ELD DG D P++
Sbjct: 319 PDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVI 378
Query: 457 CNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLY 516
+ + +TT + F V+ I + AFVASEYP+IL + +HCS+ QQ+ MAQ KKV G+ L
Sbjct: 379 YHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLL 438
Query: 517 TEAPLPSESYLPSPEKLKRMIIVKGKKL 544
T+ S LPSP +LKR I++K KKL
Sbjct: 439 TKPVEISADGLPSPNQLKRKILIKHKKL 466
>gi|33598946 phospholipase C, gamma 1 isoform b [Homo sapiens]
Length = 1290
Score = 185 bits (470), Expect = 2e-46
Identities = 109/299 (36%), Positives = 171/299 (57%), Gaps = 15/299 (5%)
Query: 576 QKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYP-EDFVNY 634
+++ ++ ELS+LV C+ V + + ++ + Y +M SF ET+A + N+ + F+ Y
Sbjct: 944 ERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQY 1003
Query: 635 NKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYV 694
N+ LSRIYP R+DSSN +P W CG Q+VA+NFQTP M ++ F+ CGYV
Sbjct: 1004 NRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYV 1063
Query: 695 LRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEI 754
L+PS MRDE F K L G+ P A+ I+++ ++ PK +G ++ P+V IE+
Sbjct: 1064 LQPSTMRDEA--FDPFDKSSLRGLEPCAISIEVLGARHLPKN----GRG-IVCPFVEIEV 1116
Query: 755 HGIPADCSEQRTKTVQQNSDNPIFD-ETFEFQVNLPELAMIRFVVLDDDYIGDE-FIGQY 812
G D ++Q+T+ V N NP++ + F FQ++ PE A +RFVV ++D D+ F+ Q
Sbjct: 1117 AGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQA 1176
Query: 813 TIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKVRE 871
T P + L+ GYR VPL++ + +E +L + I I G LS G +RE
Sbjct: 1177 TFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENG-----DLSPFSGTSLRE 1230
Score = 185 bits (469), Expect = 2e-46
Identities = 137/448 (30%), Positives = 217/448 (48%), Gaps = 50/448 (11%)
Query: 125 RPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQI 184
+ + R + F + + + + W +E A +DI IKEIR GK + F D+
Sbjct: 41 KKSQRPERKTFQVKLETRQITWSRGADKIEGA-IDIREIKEIRPGKTSRDF------DRY 93
Query: 185 CEDCAFS--------ILHGENY--ESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEG 234
ED AF IL+G + ++L L A S D N+W+ GL +L+ + Q ++
Sbjct: 94 QEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQI 153
Query: 235 NQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLN---PTLKEAKIRL--------- 282
+ WL+ F + D + + ++ Q+N P ++ + RL
Sbjct: 154 ER------WLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGD 207
Query: 283 ----KFKEIQKSKEKLTTRVTEEEFCEAFC-ELCTRPEVYFLLVQISKNKEYLDANDLML 337
+F ++ +S + + F EA RPE+ V + + +++L L
Sbjct: 208 ITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPEL--CRVSLPEFQQFLLDYQGEL 265
Query: 338 FLEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVA 397
+ V D +R E + + +D F +L S E +++ + V
Sbjct: 266 WAVDRLQVQEFMLSFLRDPLREIE-------EPYFFLDEFVTFLFSKENSVWNSQLDAVC 318
Query: 398 QD-MTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPIL 456
D M PLSHY+I++SHNTYL DQF + + Y R L+MGCR +ELD DG D P++
Sbjct: 319 PDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVI 378
Query: 457 CNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLY 516
+ + +TT + F V+ I + AFVASEYP+IL + +HCS+ QQ+ MAQ KKV G+ L
Sbjct: 379 YHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLL 438
Query: 517 TEAPLPSESYLPSPEKLKRMIIVKGKKL 544
T+ S LPSP +LKR I++K KKL
Sbjct: 439 TKPVEISADGLPSPNQLKRKILIKHKKL 466
>gi|11386139 phospholipase C beta 3 [Homo sapiens]
Length = 1234
Score = 184 bits (468), Expect = 3e-46
Identities = 109/283 (38%), Positives = 160/283 (56%), Gaps = 15/283 (5%)
Query: 552 EGEVTDEDEEAEMS-RRMSVDYNGEQKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYW 610
E E DE+EE + ++ + D ++ E+S LV+ + V+++ FE + K +
Sbjct: 556 EDEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIEPVKFKSFEAARKRNKCF 615
Query: 611 EMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMN 670
EM SF ET+A + P +FV YNK+ LSRIYP R+DSSN PQ FWN GCQ+VA+N
Sbjct: 616 EMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALN 675
Query: 671 FQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISG 730
FQT M L+ G F NG GY+L+P MR F T+ I+ G+ AL +K+ISG
Sbjct: 676 FQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGIVANALRVKVISG 735
Query: 731 QNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQ-RTKTVQQNSDNPIFD-ETFEF-QVN 787
Q K + YV +++ G+P D + RT+T Q NS NP++D E F+F +V
Sbjct: 736 QFLSDRK--------VGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEPFDFPKVV 787
Query: 788 LPELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRS 830
LP LA +R ++ G +F+G +P ++ GY +V LR+
Sbjct: 788 LPTLASLRIAAFEE---GGKFVGHRILPVSAIRSGYHYVCLRN 827
Score = 153 bits (387), Expect = 7e-37
Identities = 128/424 (30%), Positives = 202/424 (47%), Gaps = 44/424 (10%)
Query: 152 DLEKAKLDISAIKEIRLGKNTETFRNN--------GLADQICEDCAFSILHGE---NYES 200
++E LDIS+I++ R G+ ++ G D E+ +++ G N
Sbjct: 58 NMEVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVSGPDPVNTVF 117
Query: 201 LDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIML 260
L+ +A D A +W L L QN R +L+ + + N
Sbjct: 118 LNFMAVQDDTAKVWSEELFKLAMNILA--------QNASRNTFLRKAYTKLKLQVN---- 165
Query: 261 EDTSV---ELIKQLNPTLKEAKIRLKFKEIQKSK-EKLTTRVTEEEFCEAFC-ELCTRPE 315
+D + ++K + K + L+ ++ ++ E + E E F +LC RP+
Sbjct: 166 QDGRIPVKNILKMFSADKKRVETALESCGLKFNRSESIRPDEFSLEIFERFLNKLCLRPD 225
Query: 316 VYFLLVQI-SKNKEYLDANDLMLFLEAEQGVTHITEDICLDI--------IRRYELSEEG 366
+ +L++I +K K YL LM F+ +Q + E + + I +YE +++
Sbjct: 226 IDKILLEIGAKGKPYLTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQF 285
Query: 367 RQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPA 426
++ ++++GF++YL E I E ++ DMTQPLS Y+IN+SHNTYL Q G +
Sbjct: 286 LERDQMSMEGFSRYLGGEENGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTS 345
Query: 427 DINGYIRALKMGCRSVELDVSDG--SDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASE 484
+ Y +AL GCR VELDV G + EP + + MTT V R V+E I + AF S
Sbjct: 346 SVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSP 405
Query: 485 YPLILCLGNHC-SLPQQKVMAQQMKKVFGNKLYTEA----PLPSESYLPSPEKLKRMIIV 539
YP+IL NH S QQ MA+ + +FG+ L E PL LPSP+ L I+V
Sbjct: 406 YPVILSFENHVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQDLMGRILV 465
Query: 540 KGKK 543
K KK
Sbjct: 466 KNKK 469
>gi|117168250 phospholipase C, epsilon 1 [Homo sapiens]
Length = 2302
Score = 162 bits (411), Expect = 1e-39
Identities = 86/221 (38%), Positives = 134/221 (60%), Gaps = 11/221 (4%)
Query: 330 LDANDLMLFLEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSE--CD 387
L ND ++ + E H T D L II+++E S +G ++ +GF ++L+ E
Sbjct: 1327 LQLNDFLVNCQGE----HCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFAS 1382
Query: 388 IFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVS 447
D Q+ + +++ PLS+YYI +SHNTYL Q +G + + Y + L GCRSVELD
Sbjct: 1383 KNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCW 1441
Query: 448 DGSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQM 507
DG D PI+ + + +TT + F+ V+E I++ AF+ S+ P+I+ + NHCSLPQQ+ MA+
Sbjct: 1442 DGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIF 1501
Query: 508 KKVFGNKLYT----EAPLPSESYLPSPEKLKRMIIVKGKKL 544
K VFG KL T E + LPSP++L++ +++K KKL
Sbjct: 1502 KTVFGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKL 1542
Score = 145 bits (365), Expect = 3e-34
Identities = 82/261 (31%), Positives = 135/261 (51%), Gaps = 13/261 (4%)
Query: 604 MKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCG 663
+++ + + S +E A R+ Y + + L R YP+A RIDSSN NP FW G
Sbjct: 1749 IRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHG 1808
Query: 664 CQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDE----VSYFSANTKGILPGVS 719
Q+VA+N+QT + L+ F NGGCGYVL+P ++ D+ FS + L +
Sbjct: 1809 IQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERD-LDSMD 1867
Query: 720 PLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFD 779
P + I+SGQN C + P + +++ G+P D RTK + +N+ NP+++
Sbjct: 1868 PAVYSLTIVSGQN------VCPSNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWN 1921
Query: 780 ETFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHV 839
E F F V+ +L +RF V++++ Q IP + L+ GYRH+ LR+ +++E
Sbjct: 1922 EQFLFHVHFEDLVFLRFAVVENN--SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEIS 1979
Query: 840 TLFVHIAITNRSGGGKAQKRS 860
+LF++ + G S
Sbjct: 1980 SLFINSRRMEENSSGNTMSAS 2000
>gi|61742814 coiled-coil and C2 domain containing 1B [Homo sapiens]
Length = 858
Score = 43.1 bits (100), Expect = 0.001
Identities = 22/77 (28%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 711 TKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQ 770
T I ++ +H+ I+ G N P P G D +D +V E H +D +++ V
Sbjct: 689 TVRIFSELNSTEMHLIIVRGMNLPAPPGVTP--DDLDAFVRFEFHYPNSDQAQKSKTAVV 746
Query: 771 QNSDNPIFDETFEFQVN 787
+N+++P FD+ F+ +N
Sbjct: 747 KNTNSPEFDQLFKLNIN 763
>gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens]
Length = 749
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/80 (31%), Positives = 44/80 (55%), Gaps = 5/80 (6%)
Query: 744 DVIDPYVCIEIHGIPADCSEQRTKTVQQNSD-NPIFDETFEFQVNLPELAMIRFVVLDDD 802
D DPYV + I P + R +T N+D NP+++ETFEF ++ + ++ ++D +
Sbjct: 40 DTPDPYVELFISTTP----DSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDAN 95
Query: 803 YIGDEFIGQYTIPFECLQPG 822
Y+ DE +G T ++ G
Sbjct: 96 YVMDETLGTATFTVSSMKVG 115
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/98 (30%), Positives = 51/98 (52%), Gaps = 16/98 (16%)
Query: 747 DPYVCIEIHGIPADCSEQRTKT-VQQNSDNPIFDETFEFQ-VNLPELA--MIRFVVLDDD 802
DPYV ++H +P C + KT Q+N+ NP+++E + + ++ ++R V D+D
Sbjct: 126 DPYV--KLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDED 183
Query: 803 YIG-DEFIGQYTIPFECLQPGY---------RHVPLRS 830
+ +EFIG+ +P L+P R VPL S
Sbjct: 184 KLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLAS 221
>gi|38201692 RAS p21 protein activator 3 [Homo sapiens]
Length = 834
Score = 41.6 bits (96), Expect = 0.004
Identities = 36/122 (29%), Positives = 54/122 (44%), Gaps = 26/122 (21%)
Query: 717 GVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNP 776
GV L +I+ Q P G C DPY + + G P ++TK V++ ++NP
Sbjct: 141 GVVCHKLATRIVECQGLPIVNGQC------DPYATVTLAG-PFRSEAKKTK-VKRKTNNP 192
Query: 777 IFDETFEFQVNLP----ELAMIRFVVLDDDYI--------------GDEFIGQYTIPFEC 818
FDE F F+V P + + F D D + GDEF+G+ IP +
Sbjct: 193 QFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLKV 252
Query: 819 LQ 820
L+
Sbjct: 253 LR 254
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 40.0 bits (92), Expect = 0.012
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 743 GDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFV--VLD 800
G + DPYV I + +++T T+++N+ NP ++E+F F+V ++ ++ V VLD
Sbjct: 306 GGLSDPYVKIHLMQNGKRLKKKKT-TIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLD 364
Query: 801 DDYIG-DEFIGQYTIPFECLQPGYRH 825
D IG ++ IG+ + + RH
Sbjct: 365 YDKIGKNDAIGKVFVGYNSTGAELRH 390
Score = 35.0 bits (79), Expect = 0.39
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 10/104 (9%)
Query: 723 LHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETF 782
L + II P A G DPYV + + +P + TK V + + NP+F+E F
Sbjct: 159 LLVGIIQAAELP----ALDMGGTSDPYVKVFL--LPDKKKKFETK-VHRKTLNPVFNEQF 211
Query: 783 EFQVNLPEL---AMIRFVVLDDDYIGDEFIGQYTIPFECLQPGY 823
F+V EL ++ V D + + IG++ +P + G+
Sbjct: 212 TFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGH 255
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 40.0 bits (92), Expect = 0.012
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 743 GDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFV--VLD 800
G + DPYV I + +++T T+++N+ NP ++E+F F+V ++ ++ V VLD
Sbjct: 306 GGLSDPYVKIHLMQNGKRLKKKKT-TIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLD 364
Query: 801 DDYIG-DEFIGQYTIPFECLQPGYRH 825
D IG ++ IG+ + + RH
Sbjct: 365 YDKIGKNDAIGKVFVGYNSTGAELRH 390
Score = 35.0 bits (79), Expect = 0.39
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 10/104 (9%)
Query: 723 LHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETF 782
L + II P A G DPYV + + +P + TK V + + NP+F+E F
Sbjct: 159 LLVGIIQAAELP----ALDMGGTSDPYVKVFL--LPDKKKKFETK-VHRKTLNPVFNEQF 211
Query: 783 EFQVNLPEL---AMIRFVVLDDDYIGDEFIGQYTIPFECLQPGY 823
F+V EL ++ V D + + IG++ +P + G+
Sbjct: 212 TFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGH 255
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 40.0 bits (92), Expect = 0.012
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 743 GDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFV--VLD 800
G + DPYV I + +++T T+++N+ NP ++E+F F+V ++ ++ V VLD
Sbjct: 306 GGLSDPYVKIHLMQNGKRLKKKKT-TIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLD 364
Query: 801 DDYIG-DEFIGQYTIPFECLQPGYRH 825
D IG ++ IG+ + + RH
Sbjct: 365 YDKIGKNDAIGKVFVGYNSTGAELRH 390
Score = 35.0 bits (79), Expect = 0.39
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 10/104 (9%)
Query: 723 LHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETF 782
L + II P A G DPYV + + +P + TK V + + NP+F+E F
Sbjct: 159 LLVGIIQAAELP----ALDMGGTSDPYVKVFL--LPDKKKKFETK-VHRKTLNPVFNEQF 211
Query: 783 EFQVNLPEL---AMIRFVVLDDDYIGDEFIGQYTIPFECLQPGY 823
F+V EL ++ V D + + IG++ +P + G+
Sbjct: 212 TFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGH 255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,619,781
Number of Sequences: 37866
Number of extensions: 1911087
Number of successful extensions: 6317
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 78
Number of HSP's that attempted gapping in prelim test: 6088
Number of HSP's gapped (non-prelim): 183
length of query: 1095
length of database: 18,247,518
effective HSP length: 113
effective length of query: 982
effective length of database: 13,968,660
effective search space: 13717224120
effective search space used: 13717224120
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.