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Search of human proteins with 167614500
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167614500 lymphocyte-activation protein 3 precursor [Homo
sapiens]
(525 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167614500 lymphocyte-activation protein 3 precursor [Homo sap... 1091 0.0
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 58 2e-08
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 52 1e-06
gi|27894334 interleukin 1 receptor, type II precursor [Homo sapi... 48 3e-05
gi|4758598 interleukin 1 receptor, type II precursor [Homo sapiens] 48 3e-05
gi|30089948 protein phosphatase 1E [Homo sapiens] 47 3e-05
gi|139948432 adlican [Homo sapiens] 47 3e-05
gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens] 46 1e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 45 1e-04
gi|68161541 carcinoembryonic antigen-related cell adhesion molec... 45 1e-04
gi|19923195 carcinoembryonic antigen-related cell adhesion molec... 45 1e-04
gi|144226847 obscurin-like 1 [Homo sapiens] 45 2e-04
gi|4505419 nucleolar protein 3 [Homo sapiens] 44 5e-04
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s... 43 6e-04
gi|5730045 solute carrier family 16, member 2 [Homo sapiens] 42 0.001
gi|67188443 CD276 antigen isoform a [Homo sapiens] 42 0.002
gi|13376852 CD276 antigen isoform b [Homo sapiens] 42 0.002
gi|33356556 amelogenin (X chromosome) isoform 3 precursor [Homo ... 42 0.002
gi|33356558 amelogenin (X chromosome) isoform 2 precursor [Homo ... 42 0.002
gi|4502071 amelogenin (X chromosome) isoform 1 precursor [Homo s... 42 0.002
gi|169214048 PREDICTED: hypothetical protein [Homo sapiens] 41 0.002
gi|89057602 PREDICTED: hypothetical protein [Homo sapiens] 41 0.002
gi|37551995 PREDICTED: hypothetical protein [Homo sapiens] 41 0.002
gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 41 0.002
gi|156416026 zinc finger protein 219 [Homo sapiens] 41 0.003
gi|156415998 zinc finger protein 219 [Homo sapiens] 41 0.003
gi|156415996 zinc finger protein 219 [Homo sapiens] 41 0.003
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 40 0.004
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 40 0.004
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 40 0.004
>gi|167614500 lymphocyte-activation protein 3 precursor [Homo
sapiens]
Length = 525
Score = 1091 bits (2821), Expect = 0.0
Identities = 525/525 (100%), Positives = 525/525 (100%)
Query: 1 MWEAQFLGLLFLQPLWVAPVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAG 60
MWEAQFLGLLFLQPLWVAPVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAG
Sbjct: 1 MWEAQFLGLLFLQPLWVAPVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAG 60
Query: 61 VTWQHQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRV 120
VTWQHQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRV
Sbjct: 61 VTWQHQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRV 120
Query: 121 QLDERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLR 180
QLDERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLR
Sbjct: 121 QLDERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLR 180
Query: 181 ASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWG 240
ASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWG
Sbjct: 181 ASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWG 240
Query: 241 CILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTP 300
CILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTP
Sbjct: 241 CILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTP 300
Query: 301 PGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGS 360
PGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGS
Sbjct: 301 PGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGS 360
Query: 361 PGSLGKLLCEVTPVSGQERFVWSSLDTPSQRSFSGPWLEAQEAQLLSQPWQCQLYQGERL 420
PGSLGKLLCEVTPVSGQERFVWSSLDTPSQRSFSGPWLEAQEAQLLSQPWQCQLYQGERL
Sbjct: 361 PGSLGKLLCEVTPVSGQERFVWSSLDTPSQRSFSGPWLEAQEAQLLSQPWQCQLYQGERL 420
Query: 421 LGAAVYFTELSSPGAQRSGRAPGALPAGHLLLFLILGVLSLLLLVTGAFGFHLWRRQWRP 480
LGAAVYFTELSSPGAQRSGRAPGALPAGHLLLFLILGVLSLLLLVTGAFGFHLWRRQWRP
Sbjct: 421 LGAAVYFTELSSPGAQRSGRAPGALPAGHLLLFLILGVLSLLLLVTGAFGFHLWRRQWRP 480
Query: 481 RRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQL 525
RRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQL
Sbjct: 481 RRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQL 525
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 58.2 bits (139), Expect = 2e-08
Identities = 74/262 (28%), Positives = 104/262 (39%), Gaps = 43/262 (16%)
Query: 112 GRLPLQPRVQLDERGRQRGDFSLWLRPA-RRADAGEYRAAVHLRDRALSCRLRLRLGQAS 170
G LP Q R +R D + L PA ADAG Y R+++ + AS
Sbjct: 1994 GSLPPQAR-------SERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSAS 2046
Query: 171 MTASPPGSLRASDWVI-------LNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAE 223
+ PP + +S + LNC + A V W+R RG G +P PH +
Sbjct: 2047 DASPPPVKIESSSPSVTEGQTLDLNCVVAGSAH-AQVTWYR-RG-GSLP----PHTQVHG 2099
Query: 224 SFLFLPQVSPMDSGPWGCILTYRDG-----FNVSIMYN-------LTVLGLEPP---TPL 268
S L LPQVSP DSG + C + G VS+++ V G P P
Sbjct: 2100 SRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPS 2159
Query: 269 TVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQA 328
+ + G + L C +P ++ W GG L LRL V+ A +
Sbjct: 2160 SSHVAEGQTLDLNCVVPG----QAHAQVTWHKRGG--SLPARHQTHGSLLRLHQVTPADS 2213
Query: 329 GTYTCHIHLQEQQLNATVTLAI 350
G Y CH+ L A+V + I
Sbjct: 2214 GEYVCHVVGTSGPLEASVLVTI 2235
Score = 48.9 bits (115), Expect = 1e-05
Identities = 63/247 (25%), Positives = 94/247 (38%), Gaps = 39/247 (15%)
Query: 142 ADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGS------------LRASDWVILNC 189
AD+GEY + AL + + + ++ + S PGS + + + LNC
Sbjct: 2689 ADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNC 2748
Query: 190 SFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCILTYRDG- 248
A V W + RG G +P HH S L L VSP DSG + C + G
Sbjct: 2749 VVPGQAH-AQVTWHK-RG-GSLP----SHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGP 2801
Query: 249 FNVSIMYNLTVLGLE----------PPT---PLTVYAGAGSRVGLPCRLPAGVGTRSFLT 295
S++ + G PP P + G + L C +P ++
Sbjct: 2802 LEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPG----QAHAQ 2857
Query: 296 AKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTP 355
W GG +L LRL VS A +G Y+C + L A+V + I +P
Sbjct: 2858 VTWHKRGG--NLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSP 2915
Query: 356 KSFGSPG 362
+PG
Sbjct: 2916 GPIPAPG 2922
Score = 43.5 bits (101), Expect = 5e-04
Identities = 57/208 (27%), Positives = 86/208 (41%), Gaps = 39/208 (18%)
Query: 174 SPPGSLRASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSP 233
S SL + LNC + P ++ W++ RG G +P R H + S L +PQV+P
Sbjct: 2540 SSSASLANGHTLDLNCLVAS-QAPHTITWYK-RG-GSLPSR----HQIVGSRLRIPQVTP 2592
Query: 234 MDSGPWGC-------------ILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGL 280
DSG + C I+T + + + + +E +P V G + L
Sbjct: 2593 ADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVV---EGQTLDL 2649
Query: 281 PC---RLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHL 337
C R P + T W GG L LRL +S A +G Y C +
Sbjct: 2650 NCVVARQPQAIIT-------WYKRGG--SLPSRHQTHGSHLRLHQMSVADSGEYVCRANN 2700
Query: 338 QEQQLNATVTLAIITVTPKSFGSPGSLG 365
L A++ +I+V+P S GSP + G
Sbjct: 2701 NIDALEASI---VISVSP-SAGSPSAPG 2724
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/180 (28%), Positives = 73/180 (40%), Gaps = 31/180 (17%)
Query: 198 ASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCILTYRDGFNVSIMYNL 257
A V W++ RG G +P R H + S L++ Q SP D+G + C + +G SI +
Sbjct: 2274 AQVTWYK-RG-GSLPAR----HQVRGSRLYIFQASPADAGQYVCRAS--NGMEASITVTV 2325
Query: 258 T---------VLGLEPPT---PLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTPPGGGP 305
T G P P + G + L C +P +S W GG
Sbjct: 2326 TGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPG----QSHAQVTWHKRGGS- 2380
Query: 306 DLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGSPGSLG 365
L V LRL S A +G Y C + L A+V ++T+ P GS +LG
Sbjct: 2381 -LPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASV---LVTIEPA--GSVPALG 2434
Score = 42.0 bits (97), Expect = 0.001
Identities = 60/216 (27%), Positives = 84/216 (38%), Gaps = 34/216 (15%)
Query: 176 PGSLRASDWVILNCSFSRPDRP-ASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPM 234
P S R ++ L+ P + A V W + RG G +P R H L L L QVSP
Sbjct: 2833 PSSSRVAEGQTLDLKCVVPGQAHAQVTWHK-RG-GNLPARHQVHGPL----LRLNQVSPA 2886
Query: 235 DSGPWGCILTYRDG-FNVSIMYNLTVLGLEP------PTPLTVYAGA-----GSRVGLPC 282
DSG + C +T G S++ + P P+ + A + G + L C
Sbjct: 2887 DSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNC 2946
Query: 283 RLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHL---QE 339
+P ++ W GG L LRL VS A +G Y C E
Sbjct: 2947 VVPG----QAHAQVTWYKRGGS--LPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPE 3000
Query: 340 QQLNATVTLAIITVTPKSFGSPGSLGKLLCEVTPVS 375
Q+ + TVT+ P S GS L + + P S
Sbjct: 3001 QEASFTVTV------PPSEGSSYRLRSPVISIDPPS 3030
Score = 40.8 bits (94), Expect = 0.003
Identities = 62/252 (24%), Positives = 98/252 (38%), Gaps = 37/252 (14%)
Query: 119 RVQLDERGRQRGDFSLWLRPARRADAGEY--RAAVHLRDRALSCRLRLRLGQASMTASPP 176
R L + R GD + R A++ D+G+Y A + L + + T
Sbjct: 3249 RSPLPWQHRLEGDTLIIPRVAQQ-DSGQYICNATSPAGHAEATIILHVESPPYATTVPEH 3307
Query: 177 GSLRASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDS 236
S++A + V L C + P + W +R +P R + + L L + +P DS
Sbjct: 3308 ASVQAGETVQLQC-LAHGTPPLTFQW--SRVGSSLPGRATARNEL----LHFERAAPEDS 3360
Query: 237 GPWGCILTYRDGFNVSIMYNLTVLGLEPPTPLT-VYAGA---------------GSRVGL 280
G + C +T + G + L V G P T + AG+ G+ V
Sbjct: 3361 GRYRCRVTNKVG-SAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEF 3419
Query: 281 PCRLPAGVGT--RSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQ 338
C +P+ GT R F PPG D LR++++ Q+ GTY C H
Sbjct: 3420 HCAVPSDRGTQLRWFKEGGQLPPGHSVQ--------DGVLRIQNLDQSCQGTYICQAHGP 3471
Query: 339 EQQLNATVTLAI 350
+ A+ L I
Sbjct: 3472 WGKAQASAQLVI 3483
Score = 40.4 bits (93), Expect = 0.004
Identities = 70/267 (26%), Positives = 103/267 (38%), Gaps = 36/267 (13%)
Query: 110 RSGRLPLQPRVQLDERGRQRGDFSLWLRPARRADAGEY--RAAVHLRDRAL-------SC 160
R G LP + +V RG + L++ A ADAG+Y RA+ +
Sbjct: 2281 RGGSLPARHQV----RGSR-----LYIFQASPADAGQYVCRASNGMEASITVTVTGTQGA 2331
Query: 161 RLRLRLGQASMTASPPGSLRASDWVILNCSFSRPDRP-ASVHWFRNRGQGRVPVRESPHH 219
L G P S + ++ L+ + P + A V W + RG G +PVR H
Sbjct: 2332 NLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHK-RG-GSLPVRHQTHG 2389
Query: 220 HLAESFLFLPQVSPMDSGPWGC-ILTYRDGFNVSIMYNLTVLGLEPP---TPLTVYAGAG 275
S L L Q SP DSG + C +L S++ + G P TP +
Sbjct: 2390 ----SLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSS 2445
Query: 276 SRV--GLPCRLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTC 333
S+V G L V ++ W GG L LRL V+ A +G Y C
Sbjct: 2446 SQVAEGQTLDLNCLVAGQAHAQVTWHKRGGS--LPARHQVHGSRLRLLQVTPADSGEYVC 2503
Query: 334 HIHLQEQQLNATVTLAIITVTPKSFGS 360
+ A+V ++T+ + GS
Sbjct: 2504 RVVGSSGTQEASV---LVTIQQRLSGS 2527
Score = 36.2 bits (82), Expect = 0.075
Identities = 44/174 (25%), Positives = 65/174 (37%), Gaps = 16/174 (9%)
Query: 198 ASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCILTYRDGFNVSIMYNL 257
A++ W R G P S +A L +P ++ D+G + C+ T G +
Sbjct: 1985 ATITW-RKEGGSLPPQARSERTDIAT--LLIPAITTADAGFYLCVATSPAG-TAQARIQV 2040
Query: 258 TVLGLEPPTPLTVYAGAGS---RVGLPCRLPAGVGTRSFLTAKWTPPGGG--PDLLVTGD 312
VL +P V + S G L V + W GG P V G
Sbjct: 2041 VVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGS 2100
Query: 313 NGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVT---PKSFGSPGS 363
LRL VS A +G Y C + A++T++++ T P PGS
Sbjct: 2101 R----LRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGS 2150
Score = 35.0 bits (79), Expect = 0.17
Identities = 33/109 (30%), Positives = 44/109 (40%), Gaps = 10/109 (9%)
Query: 142 ADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLR--ASDWVILNCSFSRPDRPAS 199
ADAG+YR + L L QA S P +R A + C S P
Sbjct: 3548 ADAGQYRCTATNAAGTTQSHVLL-LVQALPQISMPQEVRVPAGSAAVFPCIASGYPTP-D 3605
Query: 200 VHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCILTYRDG 248
+ W ++ G +P P L + L LP V P D+G + C T R G
Sbjct: 3606 ISW--SKLDGSLP----PDSRLENNMLMLPSVRPQDAGTYVCTATNRQG 3648
Score = 34.3 bits (77), Expect = 0.29
Identities = 47/191 (24%), Positives = 68/191 (35%), Gaps = 20/191 (10%)
Query: 197 PASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCILTYRDGFNVSIMYN 256
P +W R G+ PV S L P V P D+G + C N S
Sbjct: 1705 PHYFYWSREDGR---PVPSGTQQRHQGSELHFPSVQPSDAGVYICTCRNLHQSNTSRAEL 1761
Query: 257 LTVLGLEPPTPLTV--YAGAGSRVGLPCRLPAGVGTRS-FLTAKWTPPGGGPDLLVTGD- 312
L P +TV R G ++S T WT G D
Sbjct: 1762 LVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDF 1821
Query: 313 NGDFTLRLEDVSQAQAGTYTC---HIHLQEQ-------QLNATVTLAIITVTPKSFG-SP 361
NG T+R +V + AGTY C ++ +Q Q + T++ ++++ P P
Sbjct: 1822 NGILTIR--NVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQP 1879
Query: 362 GSLGKLLCEVT 372
G L + C T
Sbjct: 1880 GQLAEFRCSAT 1890
Score = 31.6 bits (70), Expect = 1.9
Identities = 57/220 (25%), Positives = 88/220 (40%), Gaps = 27/220 (12%)
Query: 134 LWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQA----SMTASPPGSLRASDWVI--- 186
L L A AD+GEY V L + + + A ++ +P + +S +
Sbjct: 2392 LRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEG 2451
Query: 187 ----LNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCI 242
LNC + A V W + RG G +P R H + S L L QV+P DSG + C
Sbjct: 2452 QTLDLNCLVAGQAH-AQVTWHK-RG-GSLPAR----HQVHGSRLRLLQVTPADSGEYVCR 2504
Query: 243 LTYRDGFN-----VSIMYNLTVLGLEPPT-PLTVYAGAGSRV-GLPCRLPAGVGTRSFLT 295
+ G V+I L+ + P+ + + + S G L V +++ T
Sbjct: 2505 VVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHT 2564
Query: 296 AKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHI 335
W GG L LR+ V+ A +G Y CH+
Sbjct: 2565 ITWYKRGG--SLPSRHQIVGSRLRIPQVTPADSGEYVCHV 2602
Score = 30.8 bits (68), Expect = 3.2
Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 7/79 (8%)
Query: 261 GLEPPTPLT-----VYAGAGSRVGLPCRLPAGVGTRSF-LTAKWTPPGGGPDLLVTGDNG 314
G PP +T + A G V C + GV T W P + VT + G
Sbjct: 402 GCMPPQVVTPPRESIQASRGQTVTFTC-VAIGVPTPIINWRLNWGHIPSHPRVTVTSEGG 460
Query: 315 DFTLRLEDVSQAQAGTYTC 333
TL + DV ++ G YTC
Sbjct: 461 RGTLIIRDVKESDQGAYTC 479
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 52.0 bits (123), Expect = 1e-06
Identities = 59/221 (26%), Positives = 90/221 (40%), Gaps = 25/221 (11%)
Query: 178 SLRASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSG 237
++ D V+ C P P S W R G+ + +R + L S L + V+ DSG
Sbjct: 251 AIEGKDAVLECCVSGYP--PPSFTWLR--GEEVIQLRSKKYSLLGGSNLLISNVTDDDSG 306
Query: 238 PWGCILTYRDGFNVSIMYNLTVLGLEPP----TPLTVYAGAGSRVGLPCRLPAGVGTRSF 293
+ C++TY++ N+S LTV L PP P +YA + C V +
Sbjct: 307 MYTCVVTYKNE-NISASAELTV--LVPPWFLNHPSNLYAYESMDIEFECT----VSGKPV 359
Query: 294 LTAKWTPPGGGPDLLVTGDN----GDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLA 349
T W G D+++ D G LR+ V ++ G Y C + E + T A
Sbjct: 360 PTVNWMKNG---DVVIPSDYFQIVGGSNLRILGVVKSDEGFYQC---VAENEAGNAQTSA 413
Query: 350 IITVTPKSFGSPGSLGKLLCEVTPVSGQERFVWSSLDTPSQ 390
+ V + S L +V PV RFV S P++
Sbjct: 414 QLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAE 454
>gi|27894334 interleukin 1 receptor, type II precursor [Homo
sapiens]
Length = 398
Score = 47.8 bits (112), Expect = 3e-05
Identities = 64/267 (23%), Positives = 101/267 (37%), Gaps = 54/267 (20%)
Query: 80 LAPGPHPAAPSSWGPRPRRYTV---LSVGPGGLRSGRLP------LQPRVQL-------- 122
L P H A S R R Y L P LR ++P + PR+ L
Sbjct: 16 LQPAAHTGAARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSA 75
Query: 123 ------DERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASP- 175
+E D +LWL PA + D+G Y + LR+ + + P
Sbjct: 76 RTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPF 135
Query: 176 ---PGSLRASDWVILNC----SFSRPDRPASVHWFRNR------GQGRVPVRESPHHHLA 222
P L S +L C F+R + W+++ + + VR + H
Sbjct: 136 ISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTH---- 191
Query: 223 ESFLFLPQVSPMDSGPWGCILTYR---DGFNVSIMYNLTVLGLEPPT------PL-TVYA 272
L + V+ D+G + C+LT+ +N++ L + + T PL T+ A
Sbjct: 192 ---LLVHDVALEDAGYYRCVLTFAHEGQQYNITRSIELRIKKKKEETIPVIISPLKTISA 248
Query: 273 GAGSRVGLPCRLPAGVGTRSFLTAKWT 299
GSR+ +PC++ G GT WT
Sbjct: 249 SLGSRLTIPCKVFLGTGTPLTTMLWWT 275
>gi|4758598 interleukin 1 receptor, type II precursor [Homo sapiens]
Length = 398
Score = 47.8 bits (112), Expect = 3e-05
Identities = 64/267 (23%), Positives = 101/267 (37%), Gaps = 54/267 (20%)
Query: 80 LAPGPHPAAPSSWGPRPRRYTV---LSVGPGGLRSGRLP------LQPRVQL-------- 122
L P H A S R R Y L P LR ++P + PR+ L
Sbjct: 16 LQPAAHTGAARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSA 75
Query: 123 ------DERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASP- 175
+E D +LWL PA + D+G Y + LR+ + + P
Sbjct: 76 RTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPF 135
Query: 176 ---PGSLRASDWVILNC----SFSRPDRPASVHWFRNR------GQGRVPVRESPHHHLA 222
P L S +L C F+R + W+++ + + VR + H
Sbjct: 136 ISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTH---- 191
Query: 223 ESFLFLPQVSPMDSGPWGCILTYR---DGFNVSIMYNLTVLGLEPPT------PL-TVYA 272
L + V+ D+G + C+LT+ +N++ L + + T PL T+ A
Sbjct: 192 ---LLVHDVALEDAGYYRCVLTFAHEGQQYNITRSIELRIKKKKEETIPVIISPLKTISA 248
Query: 273 GAGSRVGLPCRLPAGVGTRSFLTAKWT 299
GSR+ +PC++ G GT WT
Sbjct: 249 SLGSRLTIPCKVFLGTGTPLTTMLWWT 275
>gi|30089948 protein phosphatase 1E [Homo sapiens]
Length = 755
Score = 47.4 bits (111), Expect = 3e-05
Identities = 20/23 (86%), Positives = 20/23 (86%)
Query: 501 ELEQEPEPEPEPEPEPEPEPEPE 523
E E EPEPEPEPEPE EPEPEPE
Sbjct: 30 EPEPEPEPEPEPEPESEPEPEPE 52
>gi|139948432 adlican [Homo sapiens]
Length = 2828
Score = 47.4 bits (111), Expect = 3e-05
Identities = 69/267 (25%), Positives = 106/267 (39%), Gaps = 37/267 (13%)
Query: 130 GDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASP----PGSLR----A 181
G+ SL +R R++D+ + R+ RL L+L P P S + A
Sbjct: 2499 GNGSLDIRSLRKSDS--VQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKITAMA 2556
Query: 182 SDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGC 241
+ LNCS + P+ V N + + +H A+ L + +S +D+G + C
Sbjct: 2557 GHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRC 2616
Query: 242 ILTYRDGFNVSIMYNLTVLGLEPPTPL----TVYAGAGSRVGLPCRLPAGVGTRSFLTAK 297
+ G + + +L V GL+P V G + LPC P G G F
Sbjct: 2617 VARNAAG-HTERLVSLKV-GLKPEANKQYHNLVSIINGETLKLPC-TPPGAGQGRF---S 2670
Query: 298 WTPPGG----GPDLL---VTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAI 350
WT P G GP L DNG T+R + S GTY C + + ++ + +
Sbjct: 2671 WTLPNGMHLEGPQTLGRVSLLDNGTLTVR--EASVFDRGTYVCRMETEYGPSVTSIPVIV 2728
Query: 351 ITV--------TPKSFGSPGSLGKLLC 369
I TP + PG+ KL C
Sbjct: 2729 IAYPPRITSEPTPVIYTRPGNTVKLNC 2755
Score = 36.2 bits (82), Expect = 0.075
Identities = 57/220 (25%), Positives = 85/220 (38%), Gaps = 31/220 (14%)
Query: 167 GQASMTASPPGSLRASDWVI------LNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHH 220
G++ + P G+++ V+ L+C+ + P S+ W G + P
Sbjct: 473 GRSWVMIEPSGAVQRDQTVLEGGPCQLSCNVKASESP-SIFWVLPDGSILKAPMDDPDSK 531
Query: 221 ---LAESFLFLPQVSPMDSGPWGCILTYRDGFNVSIMYNLTVL--GLEPPTPLTVYAG-- 273
L+ +L + + P DSG + CI RD + ++Y + V +P TV G
Sbjct: 532 FSILSSGWLRIKSMEPSDSGLYQCIAQVRDEMD-RMVYRVLVQSPSTQPAEKDTVTIGKN 590
Query: 274 AGSRVGLPCRLPAGVGTRSFLTAKWTPPGGG--PDLLVTG-----DNGDFTLRLEDVSQA 326
G V LPC A W P DL T NG TL + V +
Sbjct: 591 PGESVTLPCNALAIPEAH----LSWILPNRRIINDLANTSHVYMLPNG--TLSIPKVQVS 644
Query: 327 QAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGSPGSLGK 366
+G Y C Q+ + TV ITVT K G P G+
Sbjct: 645 DSGYYRCVAVNQQGADHFTVG---ITVTKKGSGLPSKRGR 681
Score = 29.3 bits (64), Expect = 9.2
Identities = 57/260 (21%), Positives = 95/260 (36%), Gaps = 46/260 (17%)
Query: 133 SLWLRPARRADAGEYRAA----VHLRDRALSCRLRLRLGQASMTASPPG--SLRASDWVI 186
+L++R D+G Y V R + ++ A +T + P +R +
Sbjct: 2106 TLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLK 2165
Query: 187 LNCSFSRPDRPASVHWFRNRGQGRVPVR---------ESPHHHLAESFLFLPQVSPMDSG 237
L+CS S P + W R+P + +S A L + V+ D+G
Sbjct: 2166 LDCSASGDPWPR-ILW-------RLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAG 2217
Query: 238 PWGCILTYRDG-----FNVSIMYNLTVLGLEPPTPLTVYAGAGSRV-----GLP-----C 282
+ C+ + G V ++ + + V+ G +V GLP
Sbjct: 2218 DYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISW 2277
Query: 283 RLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQ---- 338
LP G SF+ + GG V +NG TL +V + G YTC Q
Sbjct: 2278 SLPDGSLVNSFMQSD--DSGGRTKRYVVFNNG--TLYFNEVGMREEGDYTCFAENQVGKD 2333
Query: 339 EQQLNATVTLAIITVTPKSF 358
E ++ V A T+ K++
Sbjct: 2334 EMRVRVKVVTAPATIRNKTY 2353
>gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens]
Length = 1247
Score = 45.8 bits (107), Expect = 1e-04
Identities = 18/21 (85%), Positives = 19/21 (90%)
Query: 503 EQEPEPEPEPEPEPEPEPEPE 523
E EPEPEPEPEP PEPEPEP+
Sbjct: 12 EPEPEPEPEPEPAPEPEPEPK 32
Score = 44.7 bits (104), Expect = 2e-04
Identities = 18/22 (81%), Positives = 19/22 (86%)
Query: 501 ELEQEPEPEPEPEPEPEPEPEP 522
E E EPEPEPEP PEPEPEP+P
Sbjct: 12 EPEPEPEPEPEPAPEPEPEPKP 33
Score = 43.9 bits (102), Expect = 4e-04
Identities = 17/18 (94%), Positives = 17/18 (94%)
Query: 506 PEPEPEPEPEPEPEPEPE 523
PEPEPEPEPEPEP PEPE
Sbjct: 11 PEPEPEPEPEPEPAPEPE 28
Score = 41.2 bits (95), Expect = 0.002
Identities = 16/18 (88%), Positives = 16/18 (88%)
Query: 506 PEPEPEPEPEPEPEPEPE 523
P PEPEPEPEPEPEP PE
Sbjct: 9 PGPEPEPEPEPEPEPAPE 26
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/208 (25%), Positives = 83/208 (39%), Gaps = 21/208 (10%)
Query: 141 RADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLRASD-----WVILNCSFSRPD 195
+ D+GEY V SC+ R+ + + S L+ D ++ L C +
Sbjct: 4643 KKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAG-S 4701
Query: 196 RPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCILTYRDGFNVSIMY 255
P S+ WF++ + + H +FL + Q+ DSG + C T + G N
Sbjct: 4702 HPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHN-QCSG 4760
Query: 256 NLTVLGLEPP----TPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTPPG----GGPDL 307
+LTV EPP P + +RV +L A VG + +T KW G
Sbjct: 4761 HLTV--KEPPYFVEKPQSQDVNPNTRV----QLKALVGGTAPMTIKWFKDNKELHSGAAR 4814
Query: 308 LVTGDNGDFTLRLEDVSQAQAGTYTCHI 335
V D+ +L L +GTY C +
Sbjct: 4815 SVWKDDTSTSLELFAAKATDSGTYICQL 4842
Score = 34.3 bits (77), Expect = 0.29
Identities = 60/232 (25%), Positives = 88/232 (37%), Gaps = 41/232 (17%)
Query: 142 ADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLRASDW-----VILNCS-FSRPD 195
+D+G Y V SC L++ ++ S L+ ++ V++ C + P
Sbjct: 7651 SDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSP- 7709
Query: 196 RPASVHWFRNRGQ---GRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCILTYRDGFNVS 252
P SV WF + GR + A L + + DSG + CI T G +
Sbjct: 7710 -PISVSWFHEGNEISSGRKYQTTLTDNTCA---LTVNMLEESDSGDYTCIATNMAGSD-- 7763
Query: 253 IMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTA--KWTPPGG-----GP 305
E PLTV S V P + GT T+ K TPP G
Sbjct: 7764 ----------ECSAPLTVREPP-SFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGS 7812
Query: 306 DLLVTGDNGDFTLR-------LEDVSQAQAGTYTCHIHLQEQQLNATVTLAI 350
LV GD + +L L DV +Q+G YTC + + + + T L I
Sbjct: 7813 SELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYI 7864
Score = 33.5 bits (75), Expect = 0.49
Identities = 49/237 (20%), Positives = 91/237 (38%), Gaps = 42/237 (17%)
Query: 142 ADAGEY--RAAVHLRDRALSCRLRLR--------LGQASMTASPPGSLRASDWVILNCSF 191
+D GEY +A + C ++L+ L ++ A P L+AS
Sbjct: 5582 SDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQAS--------- 5632
Query: 192 SRPDRPASVHWFRNRGQGRVPVRESPHHHLA----ESFLFLPQVSPMDSGPWGCILTYRD 247
+P V W + + + +RES + + + L + P ++G + C +
Sbjct: 5633 IEGAQPIFVQWLKEKEE---VIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDG 5689
Query: 248 GFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTPPGGGPDL 307
G ++ T++ LEP + VG C L V L+ +W G L
Sbjct: 5690 GMRENMA---TLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDG---KL 5743
Query: 308 LVTGDNGDFT-------LRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKS 357
L + F+ LR+ V + AGTYT + + + + A++ V+ ++
Sbjct: 5744 LTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQV---QNNVGKSSCTAVVDVSDRA 5797
Score = 32.7 bits (73), Expect = 0.83
Identities = 44/220 (20%), Positives = 85/220 (38%), Gaps = 19/220 (8%)
Query: 143 DAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPG---SLRASDWVILNCSFSRPDRPAS 199
D+G+Y H + S L++ + + P +L+ +D V L C P
Sbjct: 7372 DSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGAD-VHLECELQGTP-PFH 7429
Query: 200 VHWFRNRGQGRVPVRESPHHHLAESFL---FLPQVSPMDSGPWGCILTYRDGFNVSIMYN 256
V W++++ + R + + ++E+FL + V D G + C T G + +
Sbjct: 7430 VSWYKDKRELRSGKK---YKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVG-- 7484
Query: 257 LTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTPPGG-----GPDLLVTG 311
++ PP + + + VG +L + ++ W G ++ ++
Sbjct: 7485 -SIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISY 7543
Query: 312 DNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAII 351
TL+ V A AG YTC I TL+++
Sbjct: 7544 SENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVL 7583
Score = 31.2 bits (69), Expect = 2.4
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 11/89 (12%)
Query: 10 LFLQPLWVAPVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAGVTWQHQPDS 69
++ +P +AP + + P E PV A+E P P P +P + ++ V +P++
Sbjct: 10803 VYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPP--PAVPEEPKKIIPEKKVPVIKKPEA 10860
Query: 70 GPPAAAPGH---------PLAPGPHPAAP 89
PP P P P PA P
Sbjct: 10861 PPPKEPEPEKVIEKPKLKPRPPPPPPAPP 10889
Score = 30.8 bits (68), Expect = 3.2
Identities = 60/275 (21%), Positives = 103/275 (37%), Gaps = 39/275 (14%)
Query: 133 SLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLRASDWVI-----L 187
S ++ + D+G+Y V + SC LR+ ++ S L D V+ +
Sbjct: 5197 SFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHM 5256
Query: 188 NCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCILTYRD 247
C S P S WF++ + + H L + + D+ + C ++
Sbjct: 5257 ECKVSG-SLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVA 5315
Query: 248 GFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTPPG----- 302
G + LTV EPP+ L G + +P + V ++ L K TPP
Sbjct: 5316 GDDACSGI-LTVK--EPPSFLVK---PGRQQAIP---DSTVEFKAIL--KGTPPFKIKWF 5364
Query: 303 -------GGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTP 355
GP + + L L V ++ G YTCH+ + ++ T+ ++T P
Sbjct: 5365 KDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHV-TNDVGSDSCTTMLLVTEPP 5423
Query: 356 K--------SFGSPGSLGKLLCEVTPVSGQERFVW 382
K G +L C++ S + R VW
Sbjct: 5424 KFVKKLEASKIVKAGDSSRLECKIAG-SPEIRVVW 5457
Score = 30.4 bits (67), Expect = 4.1
Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 6/75 (8%)
Query: 312 DNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGSPGSLGKLLCEV 371
D D L + DV + AG YTC + L ++ +T L ++ P F + L EV
Sbjct: 11169 DGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKL-VVEELPVRF-----VKTLEEEV 11222
Query: 372 TPVSGQERFVWSSLD 386
T V GQ ++ L+
Sbjct: 11223 TVVKGQPLYLSCELN 11237
Score = 30.0 bits (66), Expect = 5.4
Identities = 41/206 (19%), Positives = 77/206 (37%), Gaps = 20/206 (9%)
Query: 139 ARRADAGEYRAAVHLRDRALSCRLRLRLGQASM---TASPPGSLRASDWVILNCSFSRPD 195
AR ++G Y SC + L++ + P ++ SD V L C +
Sbjct: 4924 ARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSD-VELECEVTGTP 4982
Query: 196 RPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCILTYRDGFNVSIMY 255
P V W +N + R + + ++ L + + P D+G + CI++ G S
Sbjct: 4983 -PFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGG---SCSC 5038
Query: 256 NLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGD 315
+ V EPP+ + + + + V ++ W D ++ D+
Sbjct: 5039 STRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLK----DDQILDEDDNV 5094
Query: 316 F--------TLRLEDVSQAQAGTYTC 333
+ TL++ V +G YTC
Sbjct: 5095 YISFVDSVATLQIRSVDNGHSGRYTC 5120
>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 2 precursor [Homo sapiens]
Length = 464
Score = 45.4 bits (106), Expect = 1e-04
Identities = 65/274 (23%), Positives = 105/274 (38%), Gaps = 37/274 (13%)
Query: 114 LPLQPRVQLDERGRQRGDFSLWLRPARRADAGEYRAAVH---LRDRALSCRLRLRLGQAS 170
LP+ PR+QL G+ +L L R D G Y + +R+ L + G +
Sbjct: 185 LPVSPRLQLSN-----GNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDT 239
Query: 171 MTASPPGSL-RASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLP 229
T SP + R + L+C ++ + PA W N G + +E LF+P
Sbjct: 240 PTISPSDTYYRPGANLSLSC-YAASNPPAQYSWLIN-GTFQQSTQE----------LFIP 287
Query: 230 QVSPMDSGPWGCILTYR-DGFNVSIMYNLTVLGLEP-------PTPLTVYAGAGSRVGLP 281
++ +SG + C G N + + + V L P T G V L
Sbjct: 288 NITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLT 347
Query: 282 CRL-PAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIH--LQ 338
C G+ R F + P L G+ TL + V + AGTY C + +
Sbjct: 348 CSTNDTGISIRWFFKNQSLPSSERMKL----SQGNTTLSINPVKREDAGTYWCEVFNPIS 403
Query: 339 EQQLNATVTLAIITVTPKSFG-SPGSLGKLLCEV 371
+ Q + + P+ G SPG++ ++ V
Sbjct: 404 KNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGV 437
>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 1 precursor [Homo sapiens]
Length = 526
Score = 45.4 bits (106), Expect = 1e-04
Identities = 65/274 (23%), Positives = 105/274 (38%), Gaps = 37/274 (13%)
Query: 114 LPLQPRVQLDERGRQRGDFSLWLRPARRADAGEYRAAVH---LRDRALSCRLRLRLGQAS 170
LP+ PR+QL G+ +L L R D G Y + +R+ L + G +
Sbjct: 185 LPVSPRLQLSN-----GNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDT 239
Query: 171 MTASPPGSL-RASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLP 229
T SP + R + L+C ++ + PA W N G + +E LF+P
Sbjct: 240 PTISPSDTYYRPGANLSLSC-YAASNPPAQYSWLIN-GTFQQSTQE----------LFIP 287
Query: 230 QVSPMDSGPWGCILTYR-DGFNVSIMYNLTVLGLEP-------PTPLTVYAGAGSRVGLP 281
++ +SG + C G N + + + V L P T G V L
Sbjct: 288 NITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLT 347
Query: 282 CRL-PAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIH--LQ 338
C G+ R F + P L G+ TL + V + AGTY C + +
Sbjct: 348 CSTNDTGISIRWFFKNQSLPSSERMKL----SQGNTTLSINPVKREDAGTYWCEVFNPIS 403
Query: 339 EQQLNATVTLAIITVTPKSFG-SPGSLGKLLCEV 371
+ Q + + P+ G SPG++ ++ V
Sbjct: 404 KNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGV 437
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 44.7 bits (104), Expect = 2e-04
Identities = 45/175 (25%), Positives = 67/175 (38%), Gaps = 21/175 (12%)
Query: 182 SDWVILNCSFSRPDRPASVHWFRNRGQGR-----VPVRESPHHHLAESFLFLPQVSPMDS 236
S+ V+L C R D P V W+++ + V E PH L LP P D
Sbjct: 822 SECVMLACEVDREDAP--VRWYKDGQEVEESDFVVLENEGPHRRLV-----LPATQPSDG 874
Query: 237 GPWGCILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTA 296
G + C+ + + +++ + P + V A RV L C L R +
Sbjct: 875 GEFQCVAGDECAYFTVTITDVSSWIVYPSGKVYVAAVRLERVVLTCEL-----CRPWAEV 929
Query: 297 KWTPPGG----GPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVT 347
+WT G P LL+ ++ L L V +G Y C I + TVT
Sbjct: 930 RWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVT 984
>gi|4505419 nucleolar protein 3 [Homo sapiens]
Length = 208
Score = 43.5 bits (101), Expect = 5e-04
Identities = 19/33 (57%), Positives = 26/33 (78%), Gaps = 1/33 (3%)
Query: 493 PQAQSKIE-ELEQEPEPEPEPEPEPEPEPEPEQ 524
P+ + ++E E E EPEPE EPEP+PEPEP+ E+
Sbjct: 169 PEPEPELEPEAEAEPEPELEPEPDPEPEPDFEE 201
Score = 42.4 bits (98), Expect = 0.001
Identities = 23/49 (46%), Positives = 29/49 (59%), Gaps = 6/49 (12%)
Query: 480 PRRFSALEQGIHPPQAQSKIE-----ELEQEPEPEPEPEPEPEPEPEPE 523
P A++ G P + + ++E E E EPEPEPE EPE E EPEPE
Sbjct: 139 PEGSEAVQSGT-PEEPEPELEAEASKEAEPEPEPEPELEPEAEAEPEPE 186
Score = 38.5 bits (88), Expect = 0.015
Identities = 19/27 (70%), Positives = 19/27 (70%)
Query: 497 SKIEELEQEPEPEPEPEPEPEPEPEPE 523
SK E E EPEPE EPE E EPEPE E
Sbjct: 162 SKEAEPEPEPEPELEPEAEAEPEPELE 188
Score = 33.9 bits (76), Expect = 0.37
Identities = 16/31 (51%), Positives = 22/31 (70%), Gaps = 1/31 (3%)
Query: 493 PQAQSKIEELEQEPEPEPEPEPEPEPEPEPE 523
P+A+++ E E EPEP+PEPEP+ E E E
Sbjct: 177 PEAEAEPEP-ELEPEPDPEPEPDFEERDESE 206
>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
sapiens]
Length = 486
Score = 43.1 bits (100), Expect = 6e-04
Identities = 23/47 (48%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 480 PRRFSALEQGIHPPQAQSKIEE---LEQEPEPEPEPEPEPEPEPEPE 523
P R + E PP + E +E+EP E EPEPEPEPEPEPE
Sbjct: 329 PIRQTLPEDNEEPPALPPRTLEGLQVEEEPVYEAEPEPEPEPEPEPE 375
Score = 34.7 bits (78), Expect = 0.22
Identities = 15/28 (53%), Positives = 18/28 (64%)
Query: 496 QSKIEELEQEPEPEPEPEPEPEPEPEPE 523
+ + E E EPEPEPEPEPE + E E
Sbjct: 356 EEPVYEAEPEPEPEPEPEPENDYEDVEE 383
>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
Length = 613
Score = 42.4 bits (98), Expect = 0.001
Identities = 19/39 (48%), Positives = 26/39 (66%), Gaps = 3/39 (7%)
Query: 487 EQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQL 525
++ + P+ +S E E EPEPEP P P PEP+PEP+ L
Sbjct: 97 QEPVGSPEPES---EPEPEPEPEPVPVPPPEPQPEPQPL 132
Score = 40.8 bits (94), Expect = 0.003
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 14/63 (22%)
Query: 475 RRQWRPRRFSALEQGIHPPQAQS--------------KIEELEQEPEPEPEPEPEPEPEP 520
R +++P+ S+ PP A + + ++ +QEP PEPE EPEPEP
Sbjct: 54 RNKYQPQSGSSGPSSHSPPAAMALQSQASEEAKGPWQEADQEQQEPVGSPEPESEPEPEP 113
Query: 521 EPE 523
EPE
Sbjct: 114 EPE 116
Score = 40.0 bits (92), Expect = 0.005
Identities = 17/29 (58%), Positives = 20/29 (68%)
Query: 494 QAQSKIEELEQEPEPEPEPEPEPEPEPEP 522
+A + +E PEPE EPEPEPEPEP P
Sbjct: 91 EADQEQQEPVGSPEPESEPEPEPEPEPVP 119
Score = 40.0 bits (92), Expect = 0.005
Identities = 17/30 (56%), Positives = 19/30 (63%)
Query: 494 QAQSKIEELEQEPEPEPEPEPEPEPEPEPE 523
+ Q + E E EPEPEPEPEP P P PE
Sbjct: 95 EQQEPVGSPEPESEPEPEPEPEPVPVPPPE 124
Score = 32.3 bits (72), Expect = 1.1
Identities = 12/19 (63%), Positives = 15/19 (78%)
Query: 505 EPEPEPEPEPEPEPEPEPE 523
EP+PEP+P P+P P PE E
Sbjct: 124 EPQPEPQPLPDPAPLPELE 142
Score = 29.6 bits (65), Expect = 7.1
Identities = 12/21 (57%), Positives = 15/21 (71%)
Query: 503 EQEPEPEPEPEPEPEPEPEPE 523
E +PEP+P P+P P PE E E
Sbjct: 124 EPQPEPQPLPDPAPLPELEFE 144
>gi|67188443 CD276 antigen isoform a [Homo sapiens]
Length = 534
Score = 41.6 bits (96), Expect = 0.002
Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 129 RGDFSLWLRPARRADAGEYRAAVHLRD---RALSCRLRLRLGQASMTASPPGSLRASDWV 185
+G+ SL L+ R AD G + V +RD A+S ++ + SMT P LR D V
Sbjct: 320 QGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTV 379
Query: 186 ILNCSFSRPDRPASVHWFRNRG 207
+ CS R A V W +G
Sbjct: 380 TITCSSYRGYPEAEVFWQDGQG 401
Score = 40.0 bits (92), Expect = 0.005
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 129 RGDFSLWLRPARRADAGEYRAAVHLRD---RALSCRLRLRLGQASMTASPPGSLRASDWV 185
+G+ SL L+ R AD G + V +RD A+S ++ + SMT P LR D V
Sbjct: 102 QGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTV 161
Query: 186 ILNCSFSRPDRPASVHWFRNRG 207
+ CS + A V W +G
Sbjct: 162 TITCSSYQGYPEAEVFWQDGQG 183
Score = 29.6 bits (65), Expect = 7.1
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 10/72 (13%)
Query: 305 PDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQE-------QQLNATVTLAIITVTPKS 357
PDLL G+ +LRL+ V A G++TC + +++ Q+ A + +T+ P
Sbjct: 97 PDLLA---QGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNK 153
Query: 358 FGSPGSLGKLLC 369
PG + C
Sbjct: 154 DLRPGDTVTITC 165
Score = 29.6 bits (65), Expect = 7.1
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 10/72 (13%)
Query: 305 PDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQE-------QQLNATVTLAIITVTPKS 357
PDLL G+ +LRL+ V A G++TC + +++ Q+ A + +T+ P
Sbjct: 315 PDLLA---QGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNK 371
Query: 358 FGSPGSLGKLLC 369
PG + C
Sbjct: 372 DLRPGDTVTITC 383
>gi|13376852 CD276 antigen isoform b [Homo sapiens]
Length = 316
Score = 41.6 bits (96), Expect = 0.002
Identities = 28/82 (34%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 129 RGDFSLWLRPARRADAGEYRAAVHLRD---RALSCRLRLRLGQASMTASPPGSLRASDWV 185
+G+ SL L+ R AD G + V +RD A+S ++ + SMT P LR D V
Sbjct: 102 QGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTV 161
Query: 186 ILNCSFSRPDRPASVHWFRNRG 207
+ CS R A V W +G
Sbjct: 162 TITCSSYRGYPEAEVFWQDGQG 183
Score = 29.6 bits (65), Expect = 7.1
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 10/72 (13%)
Query: 305 PDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQE-------QQLNATVTLAIITVTPKS 357
PDLL G+ +LRL+ V A G++TC + +++ Q+ A + +T+ P
Sbjct: 97 PDLLA---QGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNK 153
Query: 358 FGSPGSLGKLLC 369
PG + C
Sbjct: 154 DLRPGDTVTITC 165
>gi|33356556 amelogenin (X chromosome) isoform 3 precursor [Homo
sapiens]
Length = 205
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 8/100 (8%)
Query: 19 PVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAGVTWQHQPDSGPPAAAPGH 78
P LQP +PVV PAQ P P P+ + HQP+ PPA P
Sbjct: 89 PTHTLQPHHHIPVV------PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQ 142
Query: 79 PLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQP 118
P P P P P+P + + + P P+QP
Sbjct: 143 PQPVQPQPHQPMQ--PQPPVHPMQPLPPQPPLPPMFPMQP 180
>gi|33356558 amelogenin (X chromosome) isoform 2 precursor [Homo
sapiens]
Length = 175
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 8/100 (8%)
Query: 19 PVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAGVTWQHQPDSGPPAAAPGH 78
P LQP +PVV PAQ P P P+ + HQP+ PPA P
Sbjct: 59 PTHTLQPHHHIPVV------PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQ 112
Query: 79 PLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQP 118
P P P P P+P + + + P P+QP
Sbjct: 113 PQPVQPQPHQPMQ--PQPPVHPMQPLPPQPPLPPMFPMQP 150
>gi|4502071 amelogenin (X chromosome) isoform 1 precursor [Homo
sapiens]
Length = 191
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 8/100 (8%)
Query: 19 PVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAGVTWQHQPDSGPPAAAPGH 78
P LQP +PVV PAQ P P P+ + HQP+ PPA P
Sbjct: 75 PTHTLQPHHHIPVV------PAQQPVIPQQPMMPVPGQHSMTPIQHHQPNLPPPAQQPYQ 128
Query: 79 PLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQP 118
P P P P P+P + + + P P+QP
Sbjct: 129 PQPVQPQPHQPMQ--PQPPVHPMQPLPPQPPLPPMFPMQP 166
>gi|169214048 PREDICTED: hypothetical protein [Homo sapiens]
Length = 881
Score = 41.2 bits (95), Expect = 0.002
Identities = 86/325 (26%), Positives = 115/325 (35%), Gaps = 54/325 (16%)
Query: 58 RAGVTWQ-HQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGG-----LRS 111
RAGV+ Q H+ G P + P A + G R L GPG R
Sbjct: 283 RAGVSQQTHEFTVGVYEPLPQLSVQP---KAPETEEGAAELRLRCLGWGPGRGELSWSRD 339
Query: 112 GRLPLQPRVQLDERGRQR--GDFSLWLRPARRADAGEYRAAVHL----RDRALSCRLRLR 165
GR + E R R GD L +RP R +D Y V R+ A +
Sbjct: 340 GRALEAAESEGAETPRMRSEGDQLLIVRPVR-SDHARYTCRVRSPFGHREAAADVSVFYG 398
Query: 166 LGQASMT------ASPPGSLRASDWVILNCSF-SRPDRPASVHW-FRNRGQGRVPVRESP 217
++T A+P + A V L C+ SRP PA + W + + VP
Sbjct: 399 PDPPTITVSSDRDAAPARFVTAGSNVTLRCAAASRP--PADITWSLADPAEAAVP----- 451
Query: 218 HHHLAESFLFLPQVSPMDSGPWGCILTY-RDGFNVSIMYNLTVLGLEPPTPLTVYAGAGS 276
A S L LP V P +G + C+ R G + NLTV L P P
Sbjct: 452 ----AGSRLLLPAVGPGHAGTYACLAANPRTGRRRRSLLNLTVADLPPGAP--------- 498
Query: 277 RVGLPCRLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIH 336
C + G G RS L + + PGG P + +R VS H
Sbjct: 499 ----QCSVEGGPGDRS-LRFRCSWPGGAPAASLQFQGLPEGIRAGPVSSVLLAAVPAHPR 553
Query: 337 LQEQQLNA----TVTLAIITVTPKS 357
L + V TVTP++
Sbjct: 554 LSGVPITCLARHLVATRTCTVTPEA 578
Score = 33.9 bits (76), Expect = 0.37
Identities = 77/302 (25%), Positives = 102/302 (33%), Gaps = 57/302 (18%)
Query: 66 QPDSGPPAAAPGH----PLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRVQ 121
Q GP A G PL P P+P P+S R VL+ G G P P +
Sbjct: 193 QQVGGPLAVLVGTTIRLPLVPIPNPGPPTSLVVWRRGSKVLAAG------GLGPGAPLIS 246
Query: 122 LDERGRQRGDFS-----LWLRPARRADAGEY-----RAAVHLRDRALSCRLRLRLGQASM 171
LD R F L L A+ DAG Y RA V + + + L Q S+
Sbjct: 247 LDPAHRDHLRFDQARGVLELASAQLDDAGVYTAEVIRAGVSQQTHEFTVGVYEPLPQLSV 306
Query: 172 TASPPGSLRASDWVILNCSFSRPDRPASVHWFRNRGQGRV------PVRESPHHHLAESF 225
P + + + L C P R + W R+ GR E+P
Sbjct: 307 QPKAPETEEGAAELRLRCLGWGPGR-GELSWSRD---GRALEAAESEGAETPRMRSEGDQ 362
Query: 226 LFLPQVSPMDSGPWGCILTYRDGFNVSIMYNLTVLGLEPPTPLTV----------YAGAG 275
L + + D + C + G + G +PPT +TV + AG
Sbjct: 363 LLIVRPVRSDHARYTCRVRSPFGHREAAADVSVFYGPDPPT-ITVSSDRDAAPARFVTAG 421
Query: 276 SRVGLPC----RLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTY 331
S V L C R PA + A+ P G L L V AGTY
Sbjct: 422 SNVTLRCAAASRPPADITWSLADPAEAAVPAGS------------RLLLPAVGPGHAGTY 469
Query: 332 TC 333
C
Sbjct: 470 AC 471
>gi|89057602 PREDICTED: hypothetical protein [Homo sapiens]
Length = 881
Score = 41.2 bits (95), Expect = 0.002
Identities = 86/325 (26%), Positives = 115/325 (35%), Gaps = 54/325 (16%)
Query: 58 RAGVTWQ-HQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGG-----LRS 111
RAGV+ Q H+ G P + P A + G R L GPG R
Sbjct: 283 RAGVSQQTHEFTVGVYEPLPQLSVQP---KAPETEEGAAELRLRCLGWGPGRGELSWSRD 339
Query: 112 GRLPLQPRVQLDERGRQR--GDFSLWLRPARRADAGEYRAAVHL----RDRALSCRLRLR 165
GR + E R R GD L +RP R +D Y V R+ A +
Sbjct: 340 GRALEAAESEGAETPRMRSEGDQLLIVRPVR-SDHARYTCRVRSPFGHREAAADVSVFYG 398
Query: 166 LGQASMT------ASPPGSLRASDWVILNCSF-SRPDRPASVHW-FRNRGQGRVPVRESP 217
++T A+P + A V L C+ SRP PA + W + + VP
Sbjct: 399 PDPPTITVSSDRDAAPARFVTAGSNVTLRCAAASRP--PADITWSLADPAEAAVP----- 451
Query: 218 HHHLAESFLFLPQVSPMDSGPWGCILTY-RDGFNVSIMYNLTVLGLEPPTPLTVYAGAGS 276
A S L LP V P +G + C+ R G + NLTV L P P
Sbjct: 452 ----AGSRLLLPAVGPGHAGTYACLAANPRTGRRRRSLLNLTVADLPPGAP--------- 498
Query: 277 RVGLPCRLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIH 336
C + G G RS L + + PGG P + +R VS H
Sbjct: 499 ----QCSVEGGPGDRS-LRFRCSWPGGAPAASLQFQGLPEGIRAGPVSSVLLAAVPAHPR 553
Query: 337 LQEQQLNA----TVTLAIITVTPKS 357
L + V TVTP++
Sbjct: 554 LSGVPITCLARHLVATRTCTVTPEA 578
Score = 33.9 bits (76), Expect = 0.37
Identities = 77/302 (25%), Positives = 102/302 (33%), Gaps = 57/302 (18%)
Query: 66 QPDSGPPAAAPGH----PLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRVQ 121
Q GP A G PL P P+P P+S R VL+ G G P P +
Sbjct: 193 QQVGGPLAVLVGTTIRLPLVPIPNPGPPTSLVVWRRGSKVLAAG------GLGPGAPLIS 246
Query: 122 LDERGRQRGDFS-----LWLRPARRADAGEY-----RAAVHLRDRALSCRLRLRLGQASM 171
LD R F L L A+ DAG Y RA V + + + L Q S+
Sbjct: 247 LDPAHRDHLRFDQARGVLELASAQLDDAGVYTAEVIRAGVSQQTHEFTVGVYEPLPQLSV 306
Query: 172 TASPPGSLRASDWVILNCSFSRPDRPASVHWFRNRGQGRV------PVRESPHHHLAESF 225
P + + + L C P R + W R+ GR E+P
Sbjct: 307 QPKAPETEEGAAELRLRCLGWGPGR-GELSWSRD---GRALEAAESEGAETPRMRSEGDQ 362
Query: 226 LFLPQVSPMDSGPWGCILTYRDGFNVSIMYNLTVLGLEPPTPLTV----------YAGAG 275
L + + D + C + G + G +PPT +TV + AG
Sbjct: 363 LLIVRPVRSDHARYTCRVRSPFGHREAAADVSVFYGPDPPT-ITVSSDRDAAPARFVTAG 421
Query: 276 SRVGLPC----RLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTY 331
S V L C R PA + A+ P G L L V AGTY
Sbjct: 422 SNVTLRCAAASRPPADITWSLADPAEAAVPAGS------------RLLLPAVGPGHAGTY 469
Query: 332 TC 333
C
Sbjct: 470 AC 471
>gi|37551995 PREDICTED: hypothetical protein [Homo sapiens]
Length = 867
Score = 41.2 bits (95), Expect = 0.002
Identities = 86/325 (26%), Positives = 115/325 (35%), Gaps = 54/325 (16%)
Query: 58 RAGVTWQ-HQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGG-----LRS 111
RAGV+ Q H+ G P + P A + G R L GPG R
Sbjct: 283 RAGVSQQTHEFTVGVYEPLPQLSVQP---KAPETEEGAAELRLRCLGWGPGRGELSWSRD 339
Query: 112 GRLPLQPRVQLDERGRQR--GDFSLWLRPARRADAGEYRAAVHL----RDRALSCRLRLR 165
GR + E R R GD L +RP R +D Y V R+ A +
Sbjct: 340 GRALEAAESEGAETPRMRSEGDQLLIVRPVR-SDHARYTCRVRSPFGHREAAADVSVFYG 398
Query: 166 LGQASMT------ASPPGSLRASDWVILNCSF-SRPDRPASVHW-FRNRGQGRVPVRESP 217
++T A+P + A V L C+ SRP PA + W + + VP
Sbjct: 399 PDPPTITVSSDRDAAPARFVTAGSNVTLRCAAASRP--PADITWSLADPAEAAVP----- 451
Query: 218 HHHLAESFLFLPQVSPMDSGPWGCILTY-RDGFNVSIMYNLTVLGLEPPTPLTVYAGAGS 276
A S L LP V P +G + C+ R G + NLTV L P P
Sbjct: 452 ----AGSRLLLPAVGPGHAGTYACLAANPRTGRRRRSLLNLTVADLPPGAP--------- 498
Query: 277 RVGLPCRLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIH 336
C + G G RS L + + PGG P + +R VS H
Sbjct: 499 ----QCSVEGGPGDRS-LRFRCSWPGGAPAASLQFQGLPEGIRAGPVSSVLLAAVPAHPR 553
Query: 337 LQEQQLNA----TVTLAIITVTPKS 357
L + V TVTP++
Sbjct: 554 LSGVPITCLARHLVATRTCTVTPEA 578
Score = 33.9 bits (76), Expect = 0.37
Identities = 77/302 (25%), Positives = 102/302 (33%), Gaps = 57/302 (18%)
Query: 66 QPDSGPPAAAPGH----PLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRVQ 121
Q GP A G PL P P+P P+S R VL+ G G P P +
Sbjct: 193 QQVGGPLAVLVGTTIRLPLVPIPNPGPPTSLVVWRRGSKVLAAG------GLGPGAPLIS 246
Query: 122 LDERGRQRGDFS-----LWLRPARRADAGEY-----RAAVHLRDRALSCRLRLRLGQASM 171
LD R F L L A+ DAG Y RA V + + + L Q S+
Sbjct: 247 LDPAHRDHLRFDQARGVLELASAQLDDAGVYTAEVIRAGVSQQTHEFTVGVYEPLPQLSV 306
Query: 172 TASPPGSLRASDWVILNCSFSRPDRPASVHWFRNRGQGRV------PVRESPHHHLAESF 225
P + + + L C P R + W R+ GR E+P
Sbjct: 307 QPKAPETEEGAAELRLRCLGWGPGR-GELSWSRD---GRALEAAESEGAETPRMRSEGDQ 362
Query: 226 LFLPQVSPMDSGPWGCILTYRDGFNVSIMYNLTVLGLEPPTPLTV----------YAGAG 275
L + + D + C + G + G +PPT +TV + AG
Sbjct: 363 LLIVRPVRSDHARYTCRVRSPFGHREAAADVSVFYGPDPPT-ITVSSDRDAAPARFVTAG 421
Query: 276 SRVGLPC----RLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTY 331
S V L C R PA + A+ P G L L V AGTY
Sbjct: 422 SNVTLRCAAASRPPADITWSLADPAEAAVPAGS------------RLLLPAVGPGHAGTY 469
Query: 332 TC 333
C
Sbjct: 470 AC 471
>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
Length = 713
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/104 (29%), Positives = 44/104 (42%), Gaps = 2/104 (1%)
Query: 262 LEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLE 321
+EPPT L V G + L CR + + ++LT T G + D TL
Sbjct: 367 VEPPTDLNVTEGMAAE--LKCRTGTSMTSVNWLTPNGTLMTHGSYRVRISVLHDGTLNFT 424
Query: 322 DVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGSPGSLG 365
+V+ G YTC + A+ TL + V P + G GS G
Sbjct: 425 NVTVQDTGQYTCMVTNSAGNTTASATLNVSAVDPVAAGGTGSGG 468
>gi|156416026 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 40.8 bits (94), Expect = 0.003
Identities = 20/45 (44%), Positives = 24/45 (53%), Gaps = 5/45 (11%)
Query: 480 PRRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQ 524
P R A PPQ Q + P+PEP P+PEPEPEPE+
Sbjct: 215 PERPLAATSAAPPPQPQP-----QPPPQPEPRSVPQPEPEPEPER 254
Score = 30.8 bits (68), Expect = 3.2
Identities = 9/18 (50%), Positives = 14/18 (77%)
Query: 508 PEPEPEPEPEPEPEPEQL 525
P P+P+P+P P+PEP +
Sbjct: 226 PPPQPQPQPPPQPEPRSV 243
Score = 29.3 bits (64), Expect = 9.2
Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 492 PPQAQSK-IEELEQEPEPEPEPEPEPEPEPEPE 523
PPQ + + + + E EPEPE E P P P E
Sbjct: 235 PPQPEPRSVPQPEPEPEPEREATPTPAPAAPEE 267
>gi|156415998 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 40.8 bits (94), Expect = 0.003
Identities = 20/45 (44%), Positives = 24/45 (53%), Gaps = 5/45 (11%)
Query: 480 PRRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQ 524
P R A PPQ Q + P+PEP P+PEPEPEPE+
Sbjct: 215 PERPLAATSAAPPPQPQP-----QPPPQPEPRSVPQPEPEPEPER 254
Score = 30.8 bits (68), Expect = 3.2
Identities = 9/18 (50%), Positives = 14/18 (77%)
Query: 508 PEPEPEPEPEPEPEPEQL 525
P P+P+P+P P+PEP +
Sbjct: 226 PPPQPQPQPPPQPEPRSV 243
Score = 29.3 bits (64), Expect = 9.2
Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 492 PPQAQSK-IEELEQEPEPEPEPEPEPEPEPEPE 523
PPQ + + + + E EPEPE E P P P E
Sbjct: 235 PPQPEPRSVPQPEPEPEPEREATPTPAPAAPEE 267
>gi|156415996 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 40.8 bits (94), Expect = 0.003
Identities = 20/45 (44%), Positives = 24/45 (53%), Gaps = 5/45 (11%)
Query: 480 PRRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQ 524
P R A PPQ Q + P+PEP P+PEPEPEPE+
Sbjct: 215 PERPLAATSAAPPPQPQP-----QPPPQPEPRSVPQPEPEPEPER 254
Score = 30.8 bits (68), Expect = 3.2
Identities = 9/18 (50%), Positives = 14/18 (77%)
Query: 508 PEPEPEPEPEPEPEPEQL 525
P P+P+P+P P+PEP +
Sbjct: 226 PPPQPQPQPPPQPEPRSV 243
Score = 29.3 bits (64), Expect = 9.2
Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 492 PPQAQSK-IEELEQEPEPEPEPEPEPEPEPEPE 523
PPQ + + + + E EPEPE E P P P E
Sbjct: 235 PPQPEPRSVPQPEPEPEPEREATPTPAPAAPEE 267
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 40.4 bits (93), Expect = 0.004
Identities = 53/231 (22%), Positives = 86/231 (37%), Gaps = 16/231 (6%)
Query: 125 RGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLRASDW 184
R Q D SL + D G Y+ + + L + +A + S S
Sbjct: 446 RVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQG 505
Query: 185 VILNCSFSRPDRPAS-VHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCIL 243
V + S S P + W R + + +S H A+ L + V+P D+G + C
Sbjct: 506 VEVKVSCSASGYPTPHISWSR---ESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA 562
Query: 244 TYRDGFNVSIMYNLTVLGLEPPTPLTVYA----GAGSRVGLPCRLPAGVGTRSFLTAKWT 299
T G + +T+ +PP+ V A G L C +GV + +
Sbjct: 563 TNEVGTDQE---TVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEA-SGVPPPRVIWYR-- 616
Query: 300 PPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAI 350
GG +L + LR+ + AGTYTC + +A + LA+
Sbjct: 617 --GGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 665
Score = 30.8 bits (68), Expect = 3.2
Identities = 65/244 (26%), Positives = 91/244 (37%), Gaps = 38/244 (15%)
Query: 109 LRSGRLPLQPRVQLDERGRQRGDFSLWLRPARRADAGEYR------AAVHLRDRALSCRL 162
L+ GR PL P R R D SL L A + AG Y A RD L ++
Sbjct: 803 LKDGR-PLPP----GSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQV 857
Query: 163 RLRLGQASMTASPPGSLRASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLA 222
R+ + + AS L C S P ++ W + + PH++++
Sbjct: 858 PPRIHPTATHHITNEGVPAS----LPCVASGVPAP-TITWTK---ETNALTSRGPHYNVS 909
Query: 223 -ESFLFLPQVSPMDSGPWGCILTYRDGFNVSIMYNLTVL---------GLEPPTPLTVYA 272
E L + Q S D+G + C T GF+ M L+V PL V A
Sbjct: 910 KEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEM-RLSVNTKPRIHMNGSRNANVPLQVTA 968
Query: 273 GAGSRVGLPCRL---PAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAG 329
AG V L C P + T + + P LL +G +LRL V +G
Sbjct: 969 KAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSG-----SLRLAQVQVGDSG 1023
Query: 330 TYTC 333
Y C
Sbjct: 1024 HYEC 1027
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 40.4 bits (93), Expect = 0.004
Identities = 53/231 (22%), Positives = 86/231 (37%), Gaps = 16/231 (6%)
Query: 125 RGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLRASDW 184
R Q D SL + D G Y+ + + L + +A + S S
Sbjct: 563 RVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQG 622
Query: 185 VILNCSFSRPDRPAS-VHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCIL 243
V + S S P + W R + + +S H A+ L + V+P D+G + C
Sbjct: 623 VEVKVSCSASGYPTPHISWSR---ESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA 679
Query: 244 TYRDGFNVSIMYNLTVLGLEPPTPLTVYA----GAGSRVGLPCRLPAGVGTRSFLTAKWT 299
T G + +T+ +PP+ V A G L C +GV + +
Sbjct: 680 TNEVGTDQE---TVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEA-SGVPPPRVIWYR-- 733
Query: 300 PPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAI 350
GG +L + LR+ + AGTYTC + +A + LA+
Sbjct: 734 --GGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782
Score = 34.7 bits (78), Expect = 0.22
Identities = 54/234 (23%), Positives = 90/234 (38%), Gaps = 23/234 (9%)
Query: 110 RSGRLPLQPRVQLDERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQA 169
R R+PL PR R + SL ++P DAG Y + LR+ +
Sbjct: 3707 RKDRVPLDPR---SPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEP 3763
Query: 170 SMTASPPGSLR--ASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLF 227
A P +L A +L C S +P V W+++ + +++ + L + L
Sbjct: 3764 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVV-WWKDGQKLDFRLQQGAYRLLPSNALL 3822
Query: 228 LPQVSPMDSGPWGCILTYRDG-----FNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPC 282
L P DS + C+++ G + V++ T+ + +T+ A V L C
Sbjct: 3823 LTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMA----PVVLTC 3878
Query: 283 R---LPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTC 333
+PA + S A+ G G + +G L + AG YTC
Sbjct: 3879 HSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG-----ALEIGQALPIHAGRYTC 3927
Score = 34.3 bits (77), Expect = 0.29
Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 18/177 (10%)
Query: 193 RPDRPASVHWFRNRGQGRVPVRESP-HHHLAESFLFLPQVSPMDSGPWGCILTYRDGFN- 250
R D +HW ++ +P+R S H L L + + D+G + C+ G
Sbjct: 4243 RGDPVPDIHWIKDG----LPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAK 4298
Query: 251 ---VSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTPPGGGPDL 307
+ ++ + V +EP +TV +G V L C+ G T + + P
Sbjct: 4299 KVVILVLQSAPVFQVEPQD-MTVRSG--DDVALRCQA-TGEPTPTIEWLQAGQPLRASRR 4354
Query: 308 LVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGSPGSL 364
L T +G +L LE+V AGTY C H L + A + V + GS GS+
Sbjct: 4355 LRTLPDG--SLWLENVETGDAGTYDCVAH---NLLGSATARAFLVVRGEPQGSWGSM 4406
Score = 33.9 bits (76), Expect = 0.37
Identities = 55/209 (26%), Positives = 82/209 (39%), Gaps = 17/209 (8%)
Query: 134 LWLRPARRADAGEYR--AAVHLRDRALSCRLRLRLGQASMTASPPGSLRASDWVILNCSF 191
L L AR +D+G Y A + + L++ + + + S+ A++ V L C
Sbjct: 2035 LTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQ- 2093
Query: 192 SRPDRPASVHWFRNRGQGRVPVRESPHHHLA--ESFLFLPQVSPMDSGPWGCILTYRDGF 249
S P + W+++ GR P+ P HL+ ++ L + + D+G + C + G
Sbjct: 2094 SHAMPPPVLSWWKD---GR-PLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGH 2149
Query: 250 NVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTP-----PGGG 304
+ YNL V + P PL R G P L F W PG G
Sbjct: 2150 SEK-HYNLNVW-VAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEG 2207
Query: 305 PDLLVTGDNGDFTLRLEDVSQAQAGTYTC 333
L G L L AQ GTYTC
Sbjct: 2208 AGLQHVSAVGRL-LYLGQAQLAQEGTYTC 2235
Score = 33.1 bits (74), Expect = 0.64
Identities = 60/236 (25%), Positives = 95/236 (40%), Gaps = 16/236 (6%)
Query: 130 GDFSLWLRPARRADAGEYRA-AVHLRDR-----ALSCRLRLRLGQASMTASPPGSLRASD 183
G +L L AR +D+G Y A++ R LS + QA +R D
Sbjct: 2989 GTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGD 3048
Query: 184 WVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCIL 243
+L+C P +V W+++ GQ V + + + L + + D G + C +
Sbjct: 3049 KAVLSCETDALPEP-TVTWYKD-GQPLVLAQRTQALRGGQR-LEIQEAQVSDKGLYSCKV 3105
Query: 244 TYRDGFNVSIMYNLTVL---GLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTP 300
+ G V + LTV E P TV AGS + L C + +GV + K
Sbjct: 3106 SNVAGEAVRT-FTLTVQVPPTFENPKTETVSQVAGSPLVLTCDV-SGVPAPTVTWLKDRM 3163
Query: 301 PGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPK 356
P + G L+L + AQAGTYTC + + +A++ V P+
Sbjct: 3164 PVESSAVHGVVSRGG-RLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVL-VAPR 3217
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 40.4 bits (93), Expect = 0.004
Identities = 53/231 (22%), Positives = 86/231 (37%), Gaps = 16/231 (6%)
Query: 125 RGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLRASDW 184
R Q D SL + D G Y+ + + L + +A + S S
Sbjct: 562 RVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQG 621
Query: 185 VILNCSFSRPDRPAS-VHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCIL 243
V + S S P + W R + + +S H A+ L + V+P D+G + C
Sbjct: 622 VEVKVSCSASGYPTPHISWSR---ESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQA 678
Query: 244 TYRDGFNVSIMYNLTVLGLEPPTPLTVYA----GAGSRVGLPCRLPAGVGTRSFLTAKWT 299
T G + +T+ +PP+ V A G L C +GV + +
Sbjct: 679 TNEVGTDQE---TVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEA-SGVPPPRVIWYR-- 732
Query: 300 PPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAI 350
GG +L + LR+ + AGTYTC + +A + LA+
Sbjct: 733 --GGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 781
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,091,736
Number of Sequences: 37866
Number of extensions: 1763001
Number of successful extensions: 18050
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 411
Number of HSP's that attempted gapping in prelim test: 14769
Number of HSP's gapped (non-prelim): 3073
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.