Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 11067749
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11067749 bromodomain containing protein 3 [Homo sapiens]
(726 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 1444 0.0
gi|164419758 bromodomain containing 2 [Homo sapiens] 864 0.0
gi|4826806 bromodomain containing 2 [Homo sapiens] 864 0.0
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 751 0.0
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 751 0.0
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 647 0.0
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 647 0.0
gi|119943102 CREB binding protein isoform b [Homo sapiens] 92 2e-18
gi|119943104 CREB binding protein isoform a [Homo sapiens] 92 2e-18
gi|50345997 E1A binding protein p300 [Homo sapiens] 91 3e-18
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 83 1e-15
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 80 9e-15
gi|38788260 bromodomain PHD finger transcription factor isoform ... 78 3e-14
gi|38788274 bromodomain PHD finger transcription factor isoform ... 78 3e-14
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 76 1e-13
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 74 6e-13
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 72 2e-12
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 71 3e-12
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 71 3e-12
gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens] 70 5e-12
gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens] 70 5e-12
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 70 7e-12
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 70 7e-12
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 70 9e-12
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 70 9e-12
gi|125656165 THO complex 2 [Homo sapiens] 69 1e-11
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 69 2e-11
gi|104526627 triadin [Homo sapiens] 67 4e-11
gi|51173722 bromodomain and PHD finger-containing protein 1 isof... 67 4e-11
gi|51173720 bromodomain and PHD finger-containing protein 1 isof... 67 6e-11
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 1444 bits (3737), Expect = 0.0
Identities = 726/726 (100%), Positives = 726/726 (100%)
Query: 1 MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY 60
MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY
Sbjct: 1 MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY 60
Query: 61 QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD 120
QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD
Sbjct: 61 QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD 120
Query: 121 DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA 180
DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA
Sbjct: 121 DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA 180
Query: 181 TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK 240
TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK
Sbjct: 181 TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK 240
Query: 241 GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ 300
GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ
Sbjct: 241 GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ 300
Query: 301 HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST 360
HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST
Sbjct: 301 HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST 360
Query: 361 VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV 420
VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV
Sbjct: 361 VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV 420
Query: 421 EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL 480
EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL
Sbjct: 421 EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL 480
Query: 481 SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA 540
SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA
Sbjct: 481 SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA 540
Query: 541 NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ 600
NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ
Sbjct: 541 NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ 600
Query: 601 SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL 660
SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL
Sbjct: 601 SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL 660
Query: 661 AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS 720
AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS
Sbjct: 661 AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS 720
Query: 721 DSSDSE 726
DSSDSE
Sbjct: 721 DSSDSE 726
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 864 bits (2233), Expect = 0.0
Identities = 482/772 (62%), Positives = 549/772 (71%), Gaps = 76/772 (9%)
Query: 10 AGIPATP-GPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKL 68
A +PA P NPPPPEVSNP KPGR TNQLQY+ VV+K LWKHQFAWPF QPVDA+KL
Sbjct: 49 ASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKL 108
Query: 69 NLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQA 128
LPDYHKIIK PMDMGTIK+RLENNYYW+ASECMQDFNTMFTNCYIYNKPTDDIVLMAQ
Sbjct: 109 GLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQT 168
Query: 129 LEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGT----QQVAAVSSVSPATPFQ 184
LEKIFLQKVA MPQEE EL+ PK +K A A G+ QV AVSSVS +
Sbjct: 169 LEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALY- 227
Query: 185 SVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPP--------PPATPIVPVVPPTPPV 236
TP P I V ++P P + P P V PP P+
Sbjct: 228 --------------TPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPL 273
Query: 237 VKKKGVKRKADTTTPTTSAITASRSESPPPLS-DPKQAKVVARRESGGRPIKPPKKDLED 295
KKKGVKRKADTTTPT +AI A S + PP S +PK A++ R GRPIKPP+KDL D
Sbjct: 274 AKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPD 333
Query: 296 GEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHP 355
+ + KKGKLSE L++C+ IL+E+LSKKHAAYAWPFYKPVDA AL LHDYHDIIKHP
Sbjct: 334 SQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHP 393
Query: 356 MDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKM 415
MDLSTVKRKM+ R+Y DAQ FAADVRLMFSNCYKYNPPDH+VVAMARKLQDVFE R+AKM
Sbjct: 394 MDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKM 453
Query: 416 PDEPVEAPALPAPAA--PMVSKGAESSRSSEESSSDSG------------------SSDS 455
PDEP+E LP A P ++K + S SSEESSS+S SSDS
Sbjct: 454 PDEPLEPGPLPVSTAMPPGLAKSSSES-SSEESSSESSSEEEEEEDEEDEEEEESESSDS 512
Query: 456 EEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKA 515
EEERA RLAELQEQL+AVHEQLAALSQ P++KPK+K+EKKEK+KK+K EK + + A
Sbjct: 513 EEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRK---AEKHRGRAGA 569
Query: 516 EEEKKAKVAP-PAKQAQQKKAPAKKANSTTT----------AGRQL-KKGGKQA----SA 559
+E+ K AP P + + KKA S +G +L KK K A
Sbjct: 570 DEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPT 629
Query: 560 SYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFE 619
YDSEEEEE PMSYDEKRQLSLDIN+LPGEKLGRVVHIIQ+REPSLRDSNP+EIEIDFE
Sbjct: 630 GYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFE 689
Query: 620 TLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQL 679
TLKP+TLRELERYV SCL+KK RKP++ KK K+KEELA EKK+ELEKRLQDVSGQL
Sbjct: 690 TLKPSTLRELERYVLSCLRKKPRKPYTI--KKPVGKTKEELALEKKRELEKRLQDVSGQL 747
Query: 680 SSSKKPAR----KEKPGSAPSGGPSRLS-SSSSSESGSSSSSGSSSDSSDSE 726
+S+KKP + K + SA SRLS SSSSS+S SSSSS SSSD+SDS+
Sbjct: 748 NSTKKPPKKANEKTESSSAQQVAVSRLSASSSSSDSSSSSSSSSSSDTSDSD 799
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 864 bits (2233), Expect = 0.0
Identities = 482/772 (62%), Positives = 549/772 (71%), Gaps = 76/772 (9%)
Query: 10 AGIPATP-GPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKL 68
A +PA P NPPPPEVSNP KPGR TNQLQY+ VV+K LWKHQFAWPF QPVDA+KL
Sbjct: 49 ASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKL 108
Query: 69 NLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQA 128
LPDYHKIIK PMDMGTIK+RLENNYYW+ASECMQDFNTMFTNCYIYNKPTDDIVLMAQ
Sbjct: 109 GLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQT 168
Query: 129 LEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGT----QQVAAVSSVSPATPFQ 184
LEKIFLQKVA MPQEE EL+ PK +K A A G+ QV AVSSVS +
Sbjct: 169 LEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALY- 227
Query: 185 SVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPP--------PPATPIVPVVPPTPPV 236
TP P I V ++P P + P P V PP P+
Sbjct: 228 --------------TPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPL 273
Query: 237 VKKKGVKRKADTTTPTTSAITASRSESPPPLS-DPKQAKVVARRESGGRPIKPPKKDLED 295
KKKGVKRKADTTTPT +AI A S + PP S +PK A++ R GRPIKPP+KDL D
Sbjct: 274 AKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPD 333
Query: 296 GEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHP 355
+ + KKGKLSE L++C+ IL+E+LSKKHAAYAWPFYKPVDA AL LHDYHDIIKHP
Sbjct: 334 SQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHP 393
Query: 356 MDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKM 415
MDLSTVKRKM+ R+Y DAQ FAADVRLMFSNCYKYNPPDH+VVAMARKLQDVFE R+AKM
Sbjct: 394 MDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKM 453
Query: 416 PDEPVEAPALPAPAA--PMVSKGAESSRSSEESSSDSG------------------SSDS 455
PDEP+E LP A P ++K + S SSEESSS+S SSDS
Sbjct: 454 PDEPLEPGPLPVSTAMPPGLAKSSSES-SSEESSSESSSEEEEEEDEEDEEEEESESSDS 512
Query: 456 EEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKA 515
EEERA RLAELQEQL+AVHEQLAALSQ P++KPK+K+EKKEK+KK+K EK + + A
Sbjct: 513 EEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRK---AEKHRGRAGA 569
Query: 516 EEEKKAKVAP-PAKQAQQKKAPAKKANSTTT----------AGRQL-KKGGKQA----SA 559
+E+ K AP P + + KKA S +G +L KK K A
Sbjct: 570 DEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPT 629
Query: 560 SYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFE 619
YDSEEEEE PMSYDEKRQLSLDIN+LPGEKLGRVVHIIQ+REPSLRDSNP+EIEIDFE
Sbjct: 630 GYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFE 689
Query: 620 TLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQL 679
TLKP+TLRELERYV SCL+KK RKP++ KK K+KEELA EKK+ELEKRLQDVSGQL
Sbjct: 690 TLKPSTLRELERYVLSCLRKKPRKPYTI--KKPVGKTKEELALEKKRELEKRLQDVSGQL 747
Query: 680 SSSKKPAR----KEKPGSAPSGGPSRLS-SSSSSESGSSSSSGSSSDSSDSE 726
+S+KKP + K + SA SRLS SSSSS+S SSSSS SSSD+SDS+
Sbjct: 748 NSTKKPPKKANEKTESSSAQQVAVSRLSASSSSSDSSSSSSSSSSSDTSDSD 799
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 751 bits (1939), Expect = 0.0
Identities = 422/743 (56%), Positives = 490/743 (65%), Gaps = 90/743 (12%)
Query: 13 PATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPD 72
PA NPPPPE SNP+KP R+TNQLQY+ VV+KTLWKHQFAWPF QPVDA+KLNLPD
Sbjct: 37 PANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPD 96
Query: 73 YHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKI 132
Y+KIIK PMDMGTIKKRLENNYYW+A EC+QDFNTMFTNCYIYNKP DDIVLMA+ALEK+
Sbjct: 97 YYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKL 156
Query: 133 FLQKVAQMPQEEVELLPPAPKGKGR-KPAAGAQSAGTQQVAAVSSVS----PATPFQSVP 187
FLQK+ ++P EE E++ KG+GR + G G V + S TP Q P
Sbjct: 157 FLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTP-QPNP 215
Query: 188 PTVSQTP---------VIAATPVPTITAN---VTSVPVPPAAAPPP-----PATPIVPVV 230
P V TP +I TPV T+ T PVPP PPP P P++
Sbjct: 216 PPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPII 275
Query: 231 PPTP-PVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPP 289
TP PV KKGVKRKADTTTPTT PP +PK K+ RRES RP+KPP
Sbjct: 276 AATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPP---EPKTTKLGQRRES-SRPVKPP 331
Query: 290 KKDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYH 349
KKD+ D + K K+SE L+ C IL+EM +KKHAAYAWPFYKPVD EAL LHDY
Sbjct: 332 KKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYC 391
Query: 350 DIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFE 409
DIIKHPMD+ST+K K++ REY DAQ F ADVRLMFSNCYKYNPPDHEVVAMARKLQDVFE
Sbjct: 392 DIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFE 451
Query: 410 MRFAKMPDEP------VEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRL 463
MRFAKMPDEP V +PA+P P + + S S S SDS + DSEEERA RL
Sbjct: 452 MRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRL 511
Query: 464 AELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKV 523
AELQEQLKAVHEQLAALSQ NKPKK KEK KK+K+KEK K K + EE KK+K
Sbjct: 512 AELQEQLKAVHEQLAALSQPQQNKPKK------KEKDKKEKKKEKHKRKEEVEENKKSK- 564
Query: 524 APPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLD 583
AK+ KK ++++ + ++ + +Y+SEEE++ PMSY+EKRQLSLD
Sbjct: 565 ---AKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLD 621
Query: 584 INRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRK 643
IN+LPGEKLGRVVHIIQSREPSL++SNPDEIEIDFETLKP+TLRELERYV SCL+KK RK
Sbjct: 622 INKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK-RK 680
Query: 644 PFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLS 703
P Q +K ++ G S++
Sbjct: 681 P-----------------QAEKVDV---------------------------IAGSSKMK 696
Query: 704 SSSSSESGSSSSSGSSSDSSDSE 726
SSSES SSS S SSSDS DSE
Sbjct: 697 GFSSSESESSSES-SSSDSEDSE 718
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 751 bits (1939), Expect = 0.0
Identities = 420/742 (56%), Positives = 489/742 (65%), Gaps = 88/742 (11%)
Query: 13 PATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPD 72
PA NPPPPE SNP+KP R+TNQLQY+ VV+KTLWKHQFAWPF QPVDA+KLNLPD
Sbjct: 37 PANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPD 96
Query: 73 YHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKI 132
Y+KIIK PMDMGTIKKRLENNYYW+A EC+QDFNTMFTNCYIYNKP DDIVLMA+ALEK+
Sbjct: 97 YYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKL 156
Query: 133 FLQKVAQMPQEEVELLPPAPKGKGR-KPAAGAQSAGTQQVAAVSSVSPATPFQSV---PP 188
FLQK+ ++P EE E++ KG+GR + G G V + S Q+ PP
Sbjct: 157 FLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPP 216
Query: 189 TVSQTP---------VIAATPVPTITANV---TSVPVPPAAAPPPPATPIV-----PVVP 231
V TP +I TPV T+ T PVPP PPP P P++
Sbjct: 217 PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIA 276
Query: 232 PTP-PVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPK 290
TP PV KKGVKRKADTTTPTT PP +PK K+ RRES RP+KPPK
Sbjct: 277 ATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPP---EPKTTKLGQRRESS-RPVKPPK 332
Query: 291 KDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHD 350
KD+ D + K K+SE L+ C IL+EM +KKHAAYAWPFYKPVD EAL LHDY D
Sbjct: 333 KDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCD 392
Query: 351 IIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 410
IIKHPMD+ST+K K++ REY DAQ F ADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM
Sbjct: 393 IIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 452
Query: 411 RFAKMPDEP------VEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLA 464
RFAKMPDEP V +PA+P P + + S S S SDS + DSEEERA RLA
Sbjct: 453 RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
Query: 465 ELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVA 524
ELQEQLKAVHEQLAALSQ NKPKKK EK KK+K+KEK K K + EE KK+K
Sbjct: 513 ELQEQLKAVHEQLAALSQPQQNKPKKK------EKDKKEKKKEKHKRKEEVEENKKSK-- 564
Query: 525 PPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDI 584
AK+ KK ++++ + ++ + +Y+SEEE++ PMSY+EKRQLSLDI
Sbjct: 565 --AKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDI 622
Query: 585 NRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKP 644
N+LPGEKLGRVVHIIQSREPSL++SNPDEIEIDFETLKP+TLRELERYV SCL+KK RKP
Sbjct: 623 NKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK-RKP 681
Query: 645 FSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSS 704
Q +K ++ G S++
Sbjct: 682 -----------------QAEKVDV---------------------------IAGSSKMKG 697
Query: 705 SSSSESGSSSSSGSSSDSSDSE 726
SSSES SSS S SSSDS DSE
Sbjct: 698 FSSSESESSSES-SSSDSEDSE 718
Score = 52.8 bits (125), Expect = 1e-06
Identities = 104/522 (19%), Positives = 182/522 (34%), Gaps = 89/522 (17%)
Query: 133 FLQKVAQMPQEEVELLPPAPKGKGRKP---------------AAGAQSAGTQQVAAVSSV 177
F Q + +PQ E+ P P P A Q + AA
Sbjct: 823 FTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPP 882
Query: 178 SPATPFQSVPPTVSQTPVIAATPV---PTITANVTSVPVPPAAA--------------PP 220
PA P +V P ++QTP++ P+ P + P PP + PP
Sbjct: 883 KPARP-PAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941
Query: 221 PPATPIV-------PVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLS----- 268
P P V P +PP P ++ ++++ P + PPP
Sbjct: 942 TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQP 1001
Query: 269 ----------DPKQAKVVARRESGGRPIKP----PKKDLEDGEVPQHAGKKGKLSEHLRY 314
P Q + G +P P P++ ++ P+H + HLR
Sbjct: 1002 MQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLRE 1061
Query: 315 CDSILR----EMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREY 370
S L +M + + P + V + EL + P L VK +
Sbjct: 1062 APSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAAS--VVQPQPLVVVKEEKIHSPI 1119
Query: 371 PDAQGFAADVRLMFSNCYKYNPPDH-EVVAMARKLQDVFEMRFAKMPDEPVEAPA--LPA 427
++ F+ +R PP H E + L EM+ + + P P
Sbjct: 1120 IRSEPFSPSLRP--------EPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPP 1171
Query: 428 PAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQ---AP 484
P AP K + E + + D + + A L ++ A S
Sbjct: 1172 PGAPDKDK-----QKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQ 1226
Query: 485 VNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTT 544
+ ++KE++EK K + + EKEK +++ E + + +QA++ A++
Sbjct: 1227 FRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQ 1286
Query: 545 TAGRQLKKGGKQ----ASASYDSEEEEEGLPMS-YDEKRQLS 581
RQ ++ +Q A A+ + + + P S D++R+L+
Sbjct: 1287 QQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELA 1328
Score = 32.7 bits (73), Expect = 1.2
Identities = 75/369 (20%), Positives = 133/369 (36%), Gaps = 60/369 (16%)
Query: 206 ANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPP 265
A + P P A PA P PPT V +D+++ + S+ S E
Sbjct: 455 AKMPDEPEEPVVAVSSPAVP-----PPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQ 509
Query: 266 PLSD-PKQAKVVARRE---SGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRYC------ 315
L++ +Q K V + S + KP KK+ + E + K+ + E +
Sbjct: 510 RLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPP 569
Query: 316 ------DSILREMLSKKHAAYAW----PFYKPVDAEALELHDYHDIIKHPMDLSTVKRKM 365
++ +SKK A P Y+ + + + Y + + +D++ + +
Sbjct: 570 PKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEK 629
Query: 366 DGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM---------RFAKMP 416
GR Q ++ NP + E+ K + E+ + K
Sbjct: 630 LGRVVHIIQSREPSLK-------NSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQ 682
Query: 417 DEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAEL----QEQLKA 472
E V+ A + S +ESS S S S S DSE E A + + +EQ K
Sbjct: 683 AEKVDVIAGSSKMKGFSSSESESSSES----SSSDSEDSETEMAPKSKKKGHPGREQKKH 738
Query: 473 VHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQ 532
H + QAP P++ ++ +++++ PP Q
Sbjct: 739 HHHHHQQMQQAPAPVPQQPPPPPQQPPPPP-----------PPQQQQQPPPPPPPPSMPQ 787
Query: 533 KKAPAKKAN 541
+ APA K++
Sbjct: 788 QAAPAMKSS 796
Score = 31.2 bits (69), Expect = 3.5
Identities = 40/160 (25%), Positives = 59/160 (36%), Gaps = 16/160 (10%)
Query: 149 PPAPKGKGRKPAAGAQSAGTQQVA-AVSSVSPATPFQSVPPTVSQTPVIAATPVPTITAN 207
PP P+ + + P + QQ A A+ S P VP Q P P+ T
Sbjct: 767 PPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQP 826
Query: 208 VTSVPVP--PAAAPPPPATPIVPVVPPTPPVVKKKGV--KRKADTTTPTTSAITASRSES 263
+ +P P P P PP TPP + + V P + ++R+ +
Sbjct: 827 ILHLPQPELPPHLPQPPE-------HSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAA 879
Query: 264 PPPLSDPKQAKVVARRESGGRP----IKPPKKDLEDGEVP 299
PP A A ++ P +PP+ LED E P
Sbjct: 880 LPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPP 919
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 647 bits (1668), Expect = 0.0
Identities = 371/716 (51%), Positives = 458/716 (63%), Gaps = 69/716 (9%)
Query: 19 VNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIK 78
VNPPPPE N K GR TNQLQY+Q VV+K LWKH F+WPF +PVDA+KL LPDY+ IIK
Sbjct: 12 VNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIK 71
Query: 79 NPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVA 138
NPMD+ TIKKRLEN YY ASEC++DFNTMF+NCY+YNKP DDIVLMAQALEK+F+QK++
Sbjct: 72 NPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLS 131
Query: 139 QMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAA 198
QMPQEE + K + +K GTQQ AVSS + + Q + +
Sbjct: 132 QMPQEEQVV---GVKERIKK--------GTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV 180
Query: 199 TPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITA 258
P +++ + V A+ + V KGVKRKADTTTP TSA+ A
Sbjct: 181 FP----KTSISPLNVVQGASVNSSSQTAAQVT---------KGVKRKADTTTPATSAVKA 227
Query: 259 SRSESPPPLSDPKQAKVVARRESGGRPIKP--PKKDLEDGEVPQHAGKKGKLSEHLRYCD 316
S SE P ++ A PIK PK L D + + K K++E LR+C
Sbjct: 228 S-SEFSPTFTEKSVAL---------PPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCS 277
Query: 317 SILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGF 376
IL+EML+KKH +YAWPFY PVD AL LH+Y+D++K+PMDL T+K KMD +EY DA F
Sbjct: 278 EILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKF 337
Query: 377 AADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVSKG 436
AADVRLMF NCYKYNPPDHEVV MAR LQDVFE F+K+P EPVE+ L +++
Sbjct: 338 AADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIPIEPVESMPL-CYIKTDITET 396
Query: 437 AESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKE 496
++E SS + S DSE+ER RLA+LQEQLKAVH+QL LSQ P K KKKEK +
Sbjct: 397 TGRENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSK 456
Query: 497 KEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQ 556
KEKKK+ E + E+ + K+ ++ P K+ KQ
Sbjct: 457 KEKKKEKVNNSNENPRKMCEQMR-------LKEKSKRNQPKKR---------------KQ 494
Query: 557 ASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEI 616
SE+E+ PM+YDEKRQLSL+IN+LPG+KLGRVVHIIQSREPSL +SNPDEIEI
Sbjct: 495 QFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNPDEIEI 554
Query: 617 DFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVS 676
DFETLK +TLRELE+YV +CL+K+ KP K+ SKEEL +KK+ELEKRL DV+
Sbjct: 555 DFETLKASTLRELEKYVSACLRKRPLKP----PAKKIMMSKEELHSQKKQELEKRLLDVN 610
Query: 677 GQLSSSKKPARKEK--PGSAPSG----GPSRLSSSSSSESGSSSSSGSSSDSSDSE 726
QL+S K+ + +K P A S SSSSSSES SSSS SSSDSSDSE
Sbjct: 611 NQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSDSE 666
Score = 30.0 bits (66), Expect = 7.9
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 25/83 (30%)
Query: 426 PAPAAPMVSKGAESSRSS------EESSSD---SGSSDSEEERATRLAELQEQLKAVHEQ 476
P+ A VS+ +ESS SS E SSSD S SSDSE E + E++
Sbjct: 627 PSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSDSESEMFPKFTEVK--------- 677
Query: 477 LAALSQAPVNKPKKKKEKKEKEK 499
P + P K+ KK K +
Sbjct: 678 -------PNDSPSKENVKKMKNE 693
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 647 bits (1668), Expect = 0.0
Identities = 371/716 (51%), Positives = 458/716 (63%), Gaps = 69/716 (9%)
Query: 19 VNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIK 78
VNPPPPE N K GR TNQLQY+Q VV+K LWKH F+WPF +PVDA+KL LPDY+ IIK
Sbjct: 12 VNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIK 71
Query: 79 NPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVA 138
NPMD+ TIKKRLEN YY ASEC++DFNTMF+NCY+YNKP DDIVLMAQALEK+F+QK++
Sbjct: 72 NPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLS 131
Query: 139 QMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAA 198
QMPQEE + K + +K GTQQ AVSS + + Q + +
Sbjct: 132 QMPQEEQVV---GVKERIKK--------GTQQNIAVSSAKEKSSPSATEKVFKQQEIPSV 180
Query: 199 TPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITA 258
P +++ + V A+ + V KGVKRKADTTTP TSA+ A
Sbjct: 181 FP----KTSISPLNVVQGASVNSSSQTAAQVT---------KGVKRKADTTTPATSAVKA 227
Query: 259 SRSESPPPLSDPKQAKVVARRESGGRPIKP--PKKDLEDGEVPQHAGKKGKLSEHLRYCD 316
S SE P ++ A PIK PK L D + + K K++E LR+C
Sbjct: 228 S-SEFSPTFTEKSVAL---------PPIKENMPKNVLPDSQQQYNVVKTVKVTEQLRHCS 277
Query: 317 SILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGF 376
IL+EML+KKH +YAWPFY PVD AL LH+Y+D++K+PMDL T+K KMD +EY DA F
Sbjct: 278 EILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKF 337
Query: 377 AADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVSKG 436
AADVRLMF NCYKYNPPDHEVV MAR LQDVFE F+K+P EPVE+ L +++
Sbjct: 338 AADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKIPIEPVESMPL-CYIKTDITET 396
Query: 437 AESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKE 496
++E SS + S DSE+ER RLA+LQEQLKAVH+QL LSQ P K KKKEK +
Sbjct: 397 TGRENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSK 456
Query: 497 KEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQ 556
KEKKK+ E + E+ + K+ ++ P K+ KQ
Sbjct: 457 KEKKKEKVNNSNENPRKMCEQMR-------LKEKSKRNQPKKR---------------KQ 494
Query: 557 ASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEI 616
SE+E+ PM+YDEKRQLSL+IN+LPG+KLGRVVHIIQSREPSL +SNPDEIEI
Sbjct: 495 QFIGLKSEDEDNAKPMNYDEKRQLSLNINKLPGDKLGRVVHIIQSREPSLSNSNPDEIEI 554
Query: 617 DFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVS 676
DFETLK +TLRELE+YV +CL+K+ KP K+ SKEEL +KK+ELEKRL DV+
Sbjct: 555 DFETLKASTLRELEKYVSACLRKRPLKP----PAKKIMMSKEELHSQKKQELEKRLLDVN 610
Query: 677 GQLSSSKKPARKEK--PGSAPSG----GPSRLSSSSSSESGSSSSSGSSSDSSDSE 726
QL+S K+ + +K P A S SSSSSSES SSSS SSSDSSDSE
Sbjct: 611 NQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSDSE 666
Score = 30.0 bits (66), Expect = 7.9
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 25/83 (30%)
Query: 426 PAPAAPMVSKGAESSRSS------EESSSD---SGSSDSEEERATRLAELQEQLKAVHEQ 476
P+ A VS+ +ESS SS E SSSD S SSDSE E + E++
Sbjct: 627 PSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSDSESEMFPKFTEVK--------- 677
Query: 477 LAALSQAPVNKPKKKKEKKEKEK 499
P + P K+ KK K +
Sbjct: 678 -------PNDSPSKENVKKMKNE 693
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 92.0 bits (227), Expect = 2e-18
Identities = 90/315 (28%), Positives = 122/315 (38%), Gaps = 57/315 (18%)
Query: 147 LLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITA 206
+ PP P +P+ S+G SV AT QS P TV TP P
Sbjct: 839 MTPPQPAAP-TQPSTPVSSSGQTPTPTPGSVPSATQTQSTP-TVQAAAQAQVTPQPQTPV 896
Query: 207 NVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESP-- 264
SV P ++ P TP+ P TP + + T + SA T S+ P
Sbjct: 897 QPPSVATPQSSQQQP--TPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDV 954
Query: 265 PPLS------------DPKQAKVVARRE------SGGRPIK-----------PPKKDLED 295
P L DP ++K R E G +K P + D +
Sbjct: 955 PVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKK 1014
Query: 296 GEV---------------------PQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPF 334
EV P KK E LR E L ++ + PF
Sbjct: 1015 PEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPE-SLPF 1073
Query: 335 YKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPD 394
+PVD + L + DY DI+K+PMDLST+KRK+D +Y + + DV LMF+N + YN
Sbjct: 1074 RQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKT 1133
Query: 395 HEVVAMARKLQDVFE 409
V KL +VFE
Sbjct: 1134 SRVYKFCSKLAEVFE 1148
Score = 74.7 bits (182), Expect = 3e-13
Identities = 39/127 (30%), Positives = 69/127 (54%), Gaps = 4/127 (3%)
Query: 20 NPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLW----KHQFAWPFYQPVDAIKLNLPDYHK 75
N + ++PS+P +K + + ++ ++ TL + + PF QPVD L +PDY
Sbjct: 1030 NGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFD 1089
Query: 76 IIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQ 135
I+KNPMD+ TIK++L+ Y + + D MF N ++YN+ T + L ++F Q
Sbjct: 1090 IVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQ 1149
Query: 136 KVAQMPQ 142
++ + Q
Sbjct: 1150 EIDPVMQ 1156
Score = 42.0 bits (97), Expect = 0.002
Identities = 43/167 (25%), Positives = 69/167 (41%), Gaps = 31/167 (18%)
Query: 154 GKGRKPAAGAQSAGTQQVAAVSS----VSPATPFQSVPPTVSQTPVIAATPVPTITANVT 209
G G+ PA S G AA+ + + P PP V+Q+P+ P + A +
Sbjct: 771 GMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPP-VTQSPLHPTPPPASTAAGMP 829
Query: 210 SVP--VPPAAAPPPPAT---PIVPVVPPTPPVVKKKGVKRKADTTTPTTSAI-TASRSES 263
S+ PP PP PA P P V T TPT ++ +A++++S
Sbjct: 830 SLQHTTPPGMTPPQPAAPTQPSTP-------------VSSSGQTPTPTPGSVPSATQTQS 876
Query: 264 PPPLSDPKQAKVVARRESGGRPIKPPK----KDLEDGEVPQHAGKKG 306
P + QA+V + ++ P++PP + + P HA G
Sbjct: 877 TPTVQAAAQAQVTPQPQT---PVQPPSVATPQSSQQQPTPVHAQPPG 920
Score = 39.3 bits (90), Expect = 0.013
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 3/84 (3%)
Query: 200 PVPTITANVTSVPVPPAAAPPPPATPIVPVVP-PTPPVVKKKGVKRKADTTTPTT--SAI 256
P ++ + ++ P P P P TP P P P+P + G A T PTT +
Sbjct: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGK 1899
Query: 257 TASRSESPPPLSDPKQAKVVARRE 280
S+ +PPP + P A V A R+
Sbjct: 1900 PTSQVPAPPPPAQPPPAAVEAARQ 1923
Score = 35.4 bits (80), Expect = 0.19
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 12/92 (13%)
Query: 159 PAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPV----IAATPVPTITANVTSVPVP 214
P+ + GT + +P P Q P VS +P +A T PT + T P
Sbjct: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVS--TGKPTS 1902
Query: 215 PAAAPPPPATPIVPVVPPTPPVVKKKGVKRKA 246
APPPPA PP V + ++R+A
Sbjct: 1903 QVPAPPPPAQ------PPPAAVEAARQIEREA 1928
Score = 32.7 bits (73), Expect = 1.2
Identities = 27/114 (23%), Positives = 52/114 (45%), Gaps = 18/114 (15%)
Query: 426 PAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPV 485
P P P++ E+ +E++ D G S E +E+ E E L SQ
Sbjct: 950 PGPDVPVLEMKTETQ--AEDTEPDPGESKGEPR-----SEMME------EDLQGASQV-- 994
Query: 486 NKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKK 539
K++ + E++ + + +++K + KV+ +EE+++ A Q+ P KK
Sbjct: 995 ---KEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKK 1045
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 92.0 bits (227), Expect = 2e-18
Identities = 90/315 (28%), Positives = 122/315 (38%), Gaps = 57/315 (18%)
Query: 147 LLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITA 206
+ PP P +P+ S+G SV AT QS P TV TP P
Sbjct: 877 MTPPQPAAP-TQPSTPVSSSGQTPTPTPGSVPSATQTQSTP-TVQAAAQAQVTPQPQTPV 934
Query: 207 NVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESP-- 264
SV P ++ P TP+ P TP + + T + SA T S+ P
Sbjct: 935 QPPSVATPQSSQQQP--TPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDV 992
Query: 265 PPLS------------DPKQAKVVARRE------SGGRPIK-----------PPKKDLED 295
P L DP ++K R E G +K P + D +
Sbjct: 993 PVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKK 1052
Query: 296 GEV---------------------PQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPF 334
EV P KK E LR E L ++ + PF
Sbjct: 1053 PEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPE-SLPF 1111
Query: 335 YKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPD 394
+PVD + L + DY DI+K+PMDLST+KRK+D +Y + + DV LMF+N + YN
Sbjct: 1112 RQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKT 1171
Query: 395 HEVVAMARKLQDVFE 409
V KL +VFE
Sbjct: 1172 SRVYKFCSKLAEVFE 1186
Score = 74.7 bits (182), Expect = 3e-13
Identities = 39/127 (30%), Positives = 69/127 (54%), Gaps = 4/127 (3%)
Query: 20 NPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLW----KHQFAWPFYQPVDAIKLNLPDYHK 75
N + ++PS+P +K + + ++ ++ TL + + PF QPVD L +PDY
Sbjct: 1068 NGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFD 1127
Query: 76 IIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQ 135
I+KNPMD+ TIK++L+ Y + + D MF N ++YN+ T + L ++F Q
Sbjct: 1128 IVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQ 1187
Query: 136 KVAQMPQ 142
++ + Q
Sbjct: 1188 EIDPVMQ 1194
Score = 42.0 bits (97), Expect = 0.002
Identities = 43/167 (25%), Positives = 69/167 (41%), Gaps = 31/167 (18%)
Query: 154 GKGRKPAAGAQSAGTQQVAAVSS----VSPATPFQSVPPTVSQTPVIAATPVPTITANVT 209
G G+ PA S G AA+ + + P PP V+Q+P+ P + A +
Sbjct: 809 GMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPP-VTQSPLHPTPPPASTAAGMP 867
Query: 210 SVP--VPPAAAPPPPAT---PIVPVVPPTPPVVKKKGVKRKADTTTPTTSAI-TASRSES 263
S+ PP PP PA P P V T TPT ++ +A++++S
Sbjct: 868 SLQHTTPPGMTPPQPAAPTQPSTP-------------VSSSGQTPTPTPGSVPSATQTQS 914
Query: 264 PPPLSDPKQAKVVARRESGGRPIKPPK----KDLEDGEVPQHAGKKG 306
P + QA+V + ++ P++PP + + P HA G
Sbjct: 915 TPTVQAAAQAQVTPQPQT---PVQPPSVATPQSSQQQPTPVHAQPPG 958
Score = 39.3 bits (90), Expect = 0.013
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 3/84 (3%)
Query: 200 PVPTITANVTSVPVPPAAAPPPPATPIVPVVP-PTPPVVKKKGVKRKADTTTPTT--SAI 256
P ++ + ++ P P P P TP P P P+P + G A T PTT +
Sbjct: 1878 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGK 1937
Query: 257 TASRSESPPPLSDPKQAKVVARRE 280
S+ +PPP + P A V A R+
Sbjct: 1938 PTSQVPAPPPPAQPPPAAVEAARQ 1961
Score = 35.4 bits (80), Expect = 0.19
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 12/92 (13%)
Query: 159 PAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPV----IAATPVPTITANVTSVPVP 214
P+ + GT + +P P Q P VS +P +A T PT + T P
Sbjct: 1883 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVS--TGKPTS 1940
Query: 215 PAAAPPPPATPIVPVVPPTPPVVKKKGVKRKA 246
APPPPA PP V + ++R+A
Sbjct: 1941 QVPAPPPPAQ------PPPAAVEAARQIEREA 1966
Score = 32.7 bits (73), Expect = 1.2
Identities = 27/114 (23%), Positives = 52/114 (45%), Gaps = 18/114 (15%)
Query: 426 PAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPV 485
P P P++ E+ +E++ D G S E +E+ E E L SQ
Sbjct: 988 PGPDVPVLEMKTETQ--AEDTEPDPGESKGEPR-----SEMME------EDLQGASQV-- 1032
Query: 486 NKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKK 539
K++ + E++ + + +++K + KV+ +EE+++ A Q+ P KK
Sbjct: 1033 ---KEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKK 1083
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 91.3 bits (225), Expect = 3e-18
Identities = 81/334 (24%), Positives = 133/334 (39%), Gaps = 67/334 (20%)
Query: 139 QMPQEEVELLPPAPKGKGRK------PAAGAQSAGTQQVAAVSSVSPATP----FQSVPP 188
Q+PQ + P+P P+ GAQ + A PA P Q++ P
Sbjct: 821 QLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPAMPPGPQSQALHP 880
Query: 189 TVSQTPVIAATPVPTITANVTSVPVPP---------------AAAPPPPATPIVPVVPPT 233
QTP T +P S+P P AA+ P P P++P P T
Sbjct: 881 PPRQTPTPPTTQLPQQVQ--PSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPAT 938
Query: 234 PPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRE-SGGRPIKPPKKD 292
P + + V + + P +++ T S++ ++ K+ A+ E P +D
Sbjct: 939 P--LSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPED 996
Query: 293 LEDGEVP--------------------------------QHAGKKGKLSEHLRYCDSILR 320
+ + +V Q + G+ + + + + +
Sbjct: 997 ISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQ 1056
Query: 321 EMLSKKHAAY-----AWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQG 375
++ A Y + PF +PVD + L + DY DI+K PMDLST+KRK+D +Y +
Sbjct: 1057 ALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQ 1116
Query: 376 FAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFE 409
+ D+ LMF+N + YN V KL +VFE
Sbjct: 1117 YVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFE 1150
Score = 70.1 bits (170), Expect = 7e-12
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 3/131 (2%)
Query: 13 PATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQ-FAWPFYQPVDAIKLNLP 71
P+T + P P S K K +L+ ++ L++ + PF QPVD L +P
Sbjct: 1030 PSTSATQSSPAPGQSK--KKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP 1087
Query: 72 DYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEK 131
DY I+K+PMD+ TIK++L+ Y + + D MF N ++YN+ T + L +
Sbjct: 1088 DYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSE 1147
Query: 132 IFLQKVAQMPQ 142
+F Q++ + Q
Sbjct: 1148 VFEQEIDPVMQ 1158
Score = 34.3 bits (77), Expect = 0.42
Identities = 38/119 (31%), Positives = 46/119 (38%), Gaps = 22/119 (18%)
Query: 157 RKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPA 216
R+ A+ ++ Q + S +PATP PT Q P TP PT S P P
Sbjct: 1830 RRMASMQRTGVVGQQQGLPSPTPATP---TTPT-GQQPTTPQTPQPT------SQPQP-- 1877
Query: 217 AAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKV 275
PP P +P PV + K A TP T TA PPL P A V
Sbjct: 1878 -TPPNSMPPYLPRTQAAGPVSQGKA----AGQVTPPTPPQTAQ-----PPLPGPPPAAV 1926
Score = 33.5 bits (75), Expect = 0.71
Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 7/103 (6%)
Query: 139 QMPQEEVELLPPAPKGKGRKPAAGAQSAGT----QQVAAVSSVSPATPFQSVPPTVSQTP 194
QM Q + + P+ G + A Q+ QQ+ + +P +P Q + P +Q+P
Sbjct: 2233 QMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSP 2292
Query: 195 VIAATPVPTITANVTSVPVP---PAAAPPPPATPIVPVVPPTP 234
+ +P +N P P P PP + P + P P
Sbjct: 2293 HLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQP 2335
Score = 30.4 bits (67), Expect = 6.1
Identities = 23/85 (27%), Positives = 30/85 (35%), Gaps = 7/85 (8%)
Query: 164 QSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPA 223
Q T Q +S TP S+PP + +T VT P A PP P
Sbjct: 1861 QQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPG 1920
Query: 224 TPIVPVVPPTPPVVKKKGVKRKADT 248
PP V ++R A+T
Sbjct: 1921 -------PPPAAVEMAMQIQRAAET 1938
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 82.8 bits (203), Expect = 1e-15
Identities = 42/116 (36%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Query: 24 PEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDM 83
P SK R +QL +++ + HQ AWPF +PV + P Y+++I+ PMD+
Sbjct: 713 PSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVK--RTEAPGYYEVIRFPMDL 770
Query: 84 GTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQ 139
T+ +RL+N YY S M D +FTNC YN P + A LEK F K+ +
Sbjct: 771 KTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
Score = 66.6 bits (161), Expect = 8e-11
Identities = 35/92 (38%), Positives = 56/92 (60%), Gaps = 5/92 (5%)
Query: 317 SILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGF 376
SIL+++ K H + AWPF +PV + E Y+++I+ PMDL T+ ++ R Y + F
Sbjct: 734 SILQQV--KSHQS-AWPFMEPV--KRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLF 788
Query: 377 AADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 408
AD++ +F+NC +YNPP+ E A L+ F
Sbjct: 789 MADLQRVFTNCKEYNPPESEYYKCANILEKFF 820
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 79.7 bits (195), Expect = 9e-15
Identities = 128/617 (20%), Positives = 235/617 (38%), Gaps = 73/617 (11%)
Query: 120 DDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSP 179
+ +++ Q E ++V + ++E + + G + A T+ A + SP
Sbjct: 453 ETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASP 512
Query: 180 ATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKK 239
+S +++P A +P + V P A P P +P +K
Sbjct: 513 EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP---EK 569
Query: 240 KGVKRKADTTTPTTSAITASR-SESPPPLSDPKQAKVVARRESGG-----RPIKPPKKDL 293
+ K A+ +P + A ++SP P++AK + E+ P+K K
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSP 629
Query: 294 EDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIK 353
+ + P+ A K E + + + K+ A PV AEA +K
Sbjct: 630 AEVKSPEKA--KSPTKEEAKSPEKA--KSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVK 685
Query: 354 HPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFA 413
S K K +E + A +P E + + V E A
Sbjct: 686 AEAK-SPEKAKSPVKEEAKSPEKAK------------SPVKEEAKSPEKAKSPVKEE--A 730
Query: 414 KMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAV 473
K P E ++P +P +K E +++ + S ++ + EE R+ ++ V
Sbjct: 731 KTP-EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPV 789
Query: 474 HEQLAALSQAPVNKPKKKKEKKEKEKKKKDKE---KEKEKHKVKAEEE-KKAKVAPPAKQ 529
E+ V P+K K +++ K +KE KE+ K VK EE+ ++ KV P K+
Sbjct: 790 KEE--------VKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK 841
Query: 530 AQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPG 589
A+++KAPA ++ + K+A E++E + ++ ++ ++ +
Sbjct: 842 AEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAV----EKPKESKVEAKKEEA 897
Query: 590 EKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASG 649
E +V P+ P ++E+ E KP E+ + K K ++P +
Sbjct: 898 EDKKKV--------PTPEKEAPAKVEVK-EDAKPKEKTEVAK--KEPDDAKAKEPSKPAE 946
Query: 650 KKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSE 709
KK+AA K++ +EK +KKP K K + LS S
Sbjct: 947 KKEAAPEKKDTKEEK-----------------AKKPEEKPKTEAKAKEDDKTLSKEPSKP 989
Query: 710 SGSSSSSGSSSDSSDSE 726
+ SS+D DS+
Sbjct: 990 KAEKAEKSSSTDQKDSK 1006
Score = 58.2 bits (139), Expect = 3e-08
Identities = 73/338 (21%), Positives = 136/338 (40%), Gaps = 29/338 (8%)
Query: 398 VAMARKLQDVFEMR--FAKMPDE-PVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSD 454
+A RKL + E R F +P P P +P+ + + K E + E+S ++ +
Sbjct: 399 IAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVE 458
Query: 455 S-------------EEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKK 501
EEE+ + E +E+ E+ + + P ++ EKE K
Sbjct: 459 EQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKS 518
Query: 502 KDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASY 561
KE+ K + K+ E+++AK K ++ K+PAK+ + + +K ++ A
Sbjct: 519 PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV 578
Query: 562 DSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETL 621
S E+ + K + EK V +++ P+ S E E
Sbjct: 579 KSPEKAKS-----PAKEEAKSPAEAKSPEKAKSPVK-EEAKSPAEAKSPVKE-----EAK 627
Query: 622 KPTTLRELERYVKSCLQKKQRKPFSA-SGKKQAAKSKEELAQEKKKELEKRLQDVSGQLS 680
P ++ E+ KS +++ + P A S +K+ AKS E+ K E + + S +
Sbjct: 628 SPAEVKSPEK-AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA 686
Query: 681 SSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGS 718
+K P + + P + P + S E+ S + S
Sbjct: 687 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS 724
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 77.8 bits (190), Expect = 3e-14
Identities = 35/92 (38%), Positives = 55/92 (59%), Gaps = 2/92 (2%)
Query: 46 VVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDF 105
V+++L H+ AWPF +PVD + PDY+ +IK PMD+ T+++R++ YY +E + D
Sbjct: 2796 VLRSLQAHKMAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADM 2853
Query: 106 NTMFTNCYIYNKPTDDIVLMAQALEKIFLQKV 137
+F NC YN A+ LE F+QK+
Sbjct: 2854 TKIFDNCRYYNPSDSPFYQCAEVLESFFVQKL 2885
Score = 73.2 bits (178), Expect = 8e-13
Identities = 67/242 (27%), Positives = 103/242 (42%), Gaps = 26/242 (10%)
Query: 190 VSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVP-PTPPVVKKKGV------ 242
++Q +AA P P +T + P PP + PPPPA ++ PT P +K
Sbjct: 2643 LAQATAVAA-PCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKD 2701
Query: 243 -------KRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESG--GR--PIKPPKK 291
K+ TT+ T T P + K R ++ GR I +
Sbjct: 2702 SSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEA 2761
Query: 292 DLEDGEV-PQHAGKKGKLSEHL----RYCDSILREMLSKKHAAYAWPFYKPVDAEALELH 346
+L D V PQ + ++ + + + R + S + AWPF +PVD +
Sbjct: 2762 ELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPN--DAP 2819
Query: 347 DYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQD 406
DY+ +IK PMDL+T++ ++ R Y F AD+ +F NC YNP D A L+
Sbjct: 2820 DYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLES 2879
Query: 407 VF 408
F
Sbjct: 2880 FF 2881
Score = 30.8 bits (68), Expect = 4.6
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 8/156 (5%)
Query: 435 KGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEK 494
K A R EES S + + + L + +EQL+A + AL + +++ K
Sbjct: 2570 KQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELK 2629
Query: 495 KE-KEKKKKDKEKEKEKHKVKA--EEEKKAKVAPPAKQAQQKKAPAKK-----ANSTTTA 546
++ K KK+KD + + V A A APPA PA + + T A
Sbjct: 2630 RDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPA 2689
Query: 547 GRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSL 582
Q +K ++ +S S++++ S + K+ L
Sbjct: 2690 ASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKL 2725
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 77.8 bits (190), Expect = 3e-14
Identities = 35/92 (38%), Positives = 55/92 (59%), Gaps = 2/92 (2%)
Query: 46 VVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDF 105
V+++L H+ AWPF +PVD + PDY+ +IK PMD+ T+++R++ YY +E + D
Sbjct: 2813 VLRSLQAHKMAWPFLEPVDPN--DAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADM 2870
Query: 106 NTMFTNCYIYNKPTDDIVLMAQALEKIFLQKV 137
+F NC YN A+ LE F+QK+
Sbjct: 2871 TKIFDNCRYYNPSDSPFYQCAEVLESFFVQKL 2902
Score = 73.2 bits (178), Expect = 8e-13
Identities = 67/242 (27%), Positives = 103/242 (42%), Gaps = 26/242 (10%)
Query: 190 VSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVP-PTPPVVKKKGV------ 242
++Q +AA P P +T + P PP + PPPPA ++ PT P +K
Sbjct: 2660 LAQATAVAA-PCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKD 2718
Query: 243 -------KRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESG--GR--PIKPPKK 291
K+ TT+ T T P + K R ++ GR I +
Sbjct: 2719 SSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEA 2778
Query: 292 DLEDGEV-PQHAGKKGKLSEHL----RYCDSILREMLSKKHAAYAWPFYKPVDAEALELH 346
+L D V PQ + ++ + + + R + S + AWPF +PVD +
Sbjct: 2779 ELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPN--DAP 2836
Query: 347 DYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQD 406
DY+ +IK PMDL+T++ ++ R Y F AD+ +F NC YNP D A L+
Sbjct: 2837 DYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLES 2896
Query: 407 VF 408
F
Sbjct: 2897 FF 2898
Score = 30.8 bits (68), Expect = 4.6
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 8/156 (5%)
Query: 435 KGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEK 494
K A R EES S + + + L + +EQL+A + AL + +++ K
Sbjct: 2587 KQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELK 2646
Query: 495 KE-KEKKKKDKEKEKEKHKVKA--EEEKKAKVAPPAKQAQQKKAPAKK-----ANSTTTA 546
++ K KK+KD + + V A A APPA PA + + T A
Sbjct: 2647 RDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPA 2706
Query: 547 GRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSL 582
Q +K ++ +S S++++ S + K+ L
Sbjct: 2707 ASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKL 2742
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 75.9 bits (185), Expect = 1e-13
Identities = 97/355 (27%), Positives = 140/355 (39%), Gaps = 71/355 (20%)
Query: 421 EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL 480
+AP PA AAP ++ G +S SS SSS S S DSEEE+A + K V +
Sbjct: 197 KAPPKPARAAPKIANGKAAS-SSSSSSSSSSSDDSEEEKAAATPKKTVPKKQV------V 249
Query: 481 SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKK---APA 537
++APV K + E+E++K +K + + V PP+ +K P
Sbjct: 250 AKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPP 309
Query: 538 KKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVH 597
KKA +Q + + +S DS EEE P + K +S + P K
Sbjct: 310 KKA----VEKQQPVESSEDSSDESDSSSEEEKKPPT---KAVVSKATTKPPPAK------ 356
Query: 598 IIQSREPSLRDSNPDEIEIDFETLKP--TTLRELER--------YVKSCLQKKQ------ 641
++ E S S+ D E D KP TT + VK KQ
Sbjct: 357 --KAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQ 414
Query: 642 ----RKPFSASGKKQAAKSKEE-----LAQEKKKELEKRL------------QDVSGQLS 680
RK S+S +++++ S+EE +A K K K +D S
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474
Query: 681 SS---------KKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSSDSSDSE 726
SS K A K+KP G +S+ SS+S SS DSS+ E
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEE 529
Score = 65.5 bits (158), Expect = 2e-10
Identities = 109/471 (23%), Positives = 174/471 (36%), Gaps = 88/471 (18%)
Query: 149 PPAPKGKGRKPAAGAQSAGTQQVAAVSSV-------SPATPFQSVPP--TVSQTPVIAAT 199
PP P K A G ++ + ++ SS + ATP ++VP V++ PV AAT
Sbjct: 199 PPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAAT 258
Query: 200 PVPTITAN----------------VTSVPVPPAAAPPPPATP---IVPVVPPTPPVVKKK 240
PT ++ + + P P ++ PPP A P + PP V K++
Sbjct: 259 -TPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQ 317
Query: 241 GVKRKADTT-----------TPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPP 289
V+ D++ P T A+ + + PPP AK A S
Sbjct: 318 PVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPP------AKKAAESSSD----SSD 367
Query: 290 KKDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYH 349
ED E P K S +K P KP A +
Sbjct: 368 SDSSEDDEAPSKPAGTTKNSS-------------NKPAVTTKSPAVKPAAAPKQPVGGGQ 414
Query: 350 DIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFE 409
++ D S+ + + E + A + + + P + +R +
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474
Query: 410 MRFAKMPDEPVEAPA-------LPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATR 462
++ +E A + AAP SK A + + ESS+ S S DS EE
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAP--SKPASAKKGKAESSNSSSSDDSSEEE--- 529
Query: 463 LAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKV-----KAEE 517
+E+LK + + QAP + + K +E+E+EK K K+
Sbjct: 530 ----EEKLKG---KGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGS 582
Query: 518 EKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEE 568
KK K AK+A+ +A K + T ++ KKG K+AS+ + EEE
Sbjct: 583 LKKRKQNEAAKEAETPQAKKIKLQTPNTFPKR-KKGEKRASSPFRRVREEE 632
Score = 63.9 bits (154), Expect = 5e-10
Identities = 79/333 (23%), Positives = 136/333 (40%), Gaps = 40/333 (12%)
Query: 397 VVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSE 456
V A+K + + +E V+ P A P G +++ ++S S S +S
Sbjct: 74 VAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESS 133
Query: 457 EERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAE 516
++ + Q K V Q A P K K + + +D+ + +K K+
Sbjct: 134 DDDDEEDQKKQPVQKGVKPQAKAAKAPP---KKAKSSDSDSDSSSEDEPPKNQKPKITPV 190
Query: 517 EEKKAKVAPP-AKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEE-EGLPMSY 574
K APP +A K A K A+S++++ +S+S DSEEE+ P
Sbjct: 191 TVKAQTKAPPKPARAAPKIANGKAASSSSSS--------SSSSSSDDSEEEKAAATPKKT 242
Query: 575 DEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVK 634
K+Q+ + + P + + S DS+ DE E E KP
Sbjct: 243 VPKKQV---VAKAP----VKAATTPTRKSSSSEDSSSDEEE---EQKKP----------- 281
Query: 635 SCLQKKQRKPFSASGKKQAAKSKEEL-AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGS 693
K + P+S+ A K+ L Q KK +EK+ S + SS + + E+
Sbjct: 282 ---MKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKK 338
Query: 694 APSGGPSRLSSSSSSESGSSSSSGSSSDSSDSE 726
P+ + +S +++ + ++ SSSDSSDS+
Sbjct: 339 PPT--KAVVSKATTKPPPAKKAAESSSDSSDSD 369
Score = 60.1 bits (144), Expect = 7e-09
Identities = 118/561 (21%), Positives = 208/561 (37%), Gaps = 98/561 (17%)
Query: 152 PKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSV 211
P KG KP A A A ++ A SS S + P +Q P I TPV T+ A +
Sbjct: 145 PVQKGVKPQAKAAKAPPKK--AKSSDSDSDSSSEDEPPKNQKPKI--TPV-TVKAQTKAP 199
Query: 212 PVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPK 271
P P AAP K + A +++ ++S+ ++ SE + PK
Sbjct: 200 PKPARAAP-------------------KIANGKAASSSSSSSSSSSSDDSEEEKAAATPK 240
Query: 272 QAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYA 331
+ V ++ P+K + + + + ++ + K Y+
Sbjct: 241 KT-VPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQ---------KKPMKNKPGPYS 290
Query: 332 W--PFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYK 389
P P ++L ++ + + + D + + + + S
Sbjct: 291 SVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATT 350
Query: 390 YNPPDHEVVAMARKLQDVFEMRFAKMPDEPV--------------EAPALPAPAAPMVSK 435
PP + + D + P +P ++PA+ AAP
Sbjct: 351 KPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPV 410
Query: 436 GAES---SRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKK 492
G +R ++ SSS+ SS SEEE+ ++ + KA + AALS P+ +
Sbjct: 411 GGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKP-KATAK--AALSLPAKQAPQGSR 467
Query: 493 EKKEKEKKKKDKEKEKEKHK--VKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQL 550
+ +E+E++ K VK + +K A A P+K A KK A+ +NS
Sbjct: 468 DSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNS-------- 519
Query: 551 KKGGKQASASYDSEEEEE------GLPMSYDEKRQLSLDINRLPG---------EKLGRV 595
S+S DS EEEE G P K + + G E+ +
Sbjct: 520 -------SSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKK 572
Query: 596 VHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAK 655
++ S+ SL+ +E + ET + ++ LQ P G+K+A+
Sbjct: 573 AAVVVSKSGSLKKRKQNEAAKEAETPQAKKIK---------LQTPNTFPKRKKGEKRAS- 622
Query: 656 SKEELAQEKKKELEKRLQDVS 676
S +E++ E++ R+ D S
Sbjct: 623 SPFRRVREEEIEVDSRVADNS 643
Score = 52.4 bits (124), Expect = 1e-06
Identities = 77/325 (23%), Positives = 125/325 (38%), Gaps = 53/325 (16%)
Query: 415 MPDEPVEAPALPAPAAPMVSKGAESS------------RSSEESSSDSGSSDSEEERATR 462
M ++P ++P P+AP K + SSE+SS +S SS EE++
Sbjct: 282 MKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPT 341
Query: 463 LAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAK 522
A + + A ++ P P KK + + D ++ E A K +
Sbjct: 342 KAVVSK----------ATTKPP---PAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSS 388
Query: 523 VAPPAKQAQQKKAPAKKANSTTTAGRQLKKGG-KQASASYDSEEEEEGLPMSYDEKRQLS 581
P A K+PA K A +Q GG K + DS EE S +EK +
Sbjct: 389 NKP----AVTTKSPAVK---PAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKM 441
Query: 582 LDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQ 641
+ + + + RDS+ D E E E+ KS ++KK
Sbjct: 442 VATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSE-------EEEEKTSKSAVKKKP 494
Query: 642 RKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSR 701
+K A G AA SK A++ K E S SSS + +E+ G P
Sbjct: 495 QK--VAGG---AAPSKPASAKKGKAE--------SSNSSSSDDSSEEEEEKLKGKGSPRP 541
Query: 702 LSSSSSSESGSSSSSGSSSDSSDSE 726
+ ++ S ++ +G ++ +S+ E
Sbjct: 542 QAPKANGTSALTAQNGKAAKNSEEE 566
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 73.6 bits (179), Expect = 6e-13
Identities = 49/178 (27%), Positives = 81/178 (45%), Gaps = 23/178 (12%)
Query: 238 KKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAK---VVARRESGGRPIKPPKKDLE 294
K K V DT +++ ++S L K + + ++ +K PK+D
Sbjct: 2004 KGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEENTSINLSKQESFTSVKKPKRDD- 2062
Query: 295 DGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKH 354
S+ L C IL EM + + A WPF PV+ + + Y +IK
Sbjct: 2063 --------------SKDLALCSMILTEMETHEDA---WPFLLPVNLKLVP--GYKKVIKK 2103
Query: 355 PMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF 412
PMD ST++ K+ +YP+ + FA DVRL+F NC +N D ++ ++ FE ++
Sbjct: 2104 PMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKW 2161
Score = 62.0 bits (149), Expect = 2e-09
Identities = 34/106 (32%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
Query: 31 KPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRL 90
KP R ++ + ++++ + H+ AWPF PV+ +KL +P Y K+IK PMD TI+++L
Sbjct: 2057 KPKRDDSKDLALCSMILTEMETHEDAWPFLLPVN-LKL-VPGYKKVIKKPMDFSTIREKL 2114
Query: 91 ENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQK 136
+ Y + D +F NC +N+ DI + K F +K
Sbjct: 2115 SSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
Score = 36.6 bits (83), Expect = 0.084
Identities = 33/133 (24%), Positives = 63/133 (47%), Gaps = 6/133 (4%)
Query: 462 RLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKA 521
R + QEQ + E A Q + ++K+++KE+ K K +EK K +++ E+E +A
Sbjct: 905 RKLQKQEQARVAKE---AKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRA 961
Query: 522 KVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEE---EEGLPMSYDEKR 578
+ AK+ ++++A K ++ + +QA E E + + M E R
Sbjct: 962 QQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEAR 1021
Query: 579 QLSLDINRLPGEK 591
+ + + RL EK
Sbjct: 1022 KKAEEKERLKQEK 1034
Score = 33.1 bits (74), Expect = 0.93
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Query: 641 QRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPS 700
Q K S+ G + + Q K + L+ R+ + KKP +K S+ S S
Sbjct: 199 QTKSTSSGGGNRKCNQE----QSKNQPLDARVDKIK-----DKKPRKKAMESSSNSDSDS 249
Query: 701 RLSSSSSSESGSSSSSGSSSDSSDSE 726
SS +SSE SSS S + + E
Sbjct: 250 GTSSDTSSEGISSSDSDDLEEDEEEE 275
Score = 30.8 bits (68), Expect = 4.6
Identities = 38/177 (21%), Positives = 71/177 (40%), Gaps = 32/177 (18%)
Query: 439 SSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVN-KPKKKKEKKEK 497
SS+ SE+S+ D D EE+ E E ++ Q + S + + + ++++ +K
Sbjct: 600 SSKDSEDSNEDEEEDDEEEDE-----EDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654
Query: 498 EKKKKDKEKEKEKHKVKAEEE----------------------KKAKVAPPAKQAQQKKA 535
++ + D + E EK +K + KA + PA + ++
Sbjct: 655 DQDESDSDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQS 714
Query: 536 PAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDI--NRLPGE 590
PA S++T G + D E E +P+ Y +R+ + RL GE
Sbjct: 715 PAFLGTSSSTLTSSPHSGTSKRRRVTD--ERELRIPLEYGWQRETRIRNFGGRLQGE 769
Score = 30.8 bits (68), Expect = 4.6
Identities = 35/147 (23%), Positives = 62/147 (42%), Gaps = 24/147 (16%)
Query: 438 ESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQ--LAALSQAPVNKPKKKKEKK 495
E +R ++E+ +EE+R + EQ+K + +Q + + Q + K + ++
Sbjct: 911 EQARVAKEAKKQQAIMAAEEKRKQK-----EQIKIMKQQEKIKRIQQIRMEKELRAQQIL 965
Query: 496 EKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA----NSTTTAGRQLK 551
E +KKKK EE AK+ K+ ++K+ ++A + RQ
Sbjct: 966 EAKKKKK-------------EEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHM 1012
Query: 552 KGGKQASASYDSEEEEEGLPMSYDEKR 578
K A +EE+E DEKR
Sbjct: 1013 MLMKAMEARKKAEEKERLKQEKRDEKR 1039
Score = 30.0 bits (66), Expect = 7.9
Identities = 38/207 (18%), Positives = 89/207 (42%), Gaps = 20/207 (9%)
Query: 498 EKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQA 557
++++ +E + K + A+ A +K A++ + L+K KQ
Sbjct: 852 DRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQE 911
Query: 558 SASYDSEEEEEGLPMSYDEKR----QLSL--------DINRLPGEKLGRVVHIIQSREPS 605
A E +++ M+ +EKR Q+ + I ++ EK R I+++++
Sbjct: 912 QARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKK 971
Query: 606 LRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKP----FSASGKKQAAKSKEELA 661
++ ++ + +K +R + + ++++R+ A ++ A+ KE L
Sbjct: 972 KEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLK 1031
Query: 662 QEKKKE----LEKRLQDVSGQLSSSKK 684
QEK+ E E++L+ +L +K+
Sbjct: 1032 QEKRDEKRLNKERKLEQRRLELEMAKE 1058
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 71.6 bits (174), Expect = 2e-12
Identities = 61/181 (33%), Positives = 89/181 (49%), Gaps = 25/181 (13%)
Query: 235 PVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVAR-RESGGRPIKPPKKDL 293
P K+G KRK S + + SE D ++ +V+ R RES P P+
Sbjct: 1736 PGFPKRGQKRK--------SGYSLNFSEG-----DGRRRRVLLRGRES---PAAGPRYS- 1778
Query: 294 EDGEVPQHAGKKGKLSEH--LRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDI 351
E+G P + + H L +C+ IL EM S H A AWPF +PV+ + Y I
Sbjct: 1779 EEGLSPSKRRRLSMRNHHSDLTFCEIILMEMES--HDA-AWPFLEPVNPRLVS--GYRRI 1833
Query: 352 IKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMR 411
IK+PMD ST++ ++ Y ++ FAAD L+F NC +N D EV ++ FE R
Sbjct: 1834 IKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESR 1893
Query: 412 F 412
+
Sbjct: 1894 W 1894
Score = 57.4 bits (137), Expect = 5e-08
Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
Query: 45 VVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQD 104
+++ + H AWPF +PV+ ++ Y +IIKNPMD T+++RL Y S+ E D
Sbjct: 1804 IILMEMESHDAAWPFLEPVNPRLVS--GYRRIIKNPMDFSTMRERLLRGGYTSSEEFAAD 1861
Query: 105 FNTMFTNCYIYNKPTDDIVLMAQALEKIF 133
+F NC +N+ ++ + + F
Sbjct: 1862 ALLVFDNCQTFNEDDSEVGKAGHIMRRFF 1890
Score = 53.1 bits (126), Expect = 9e-07
Identities = 102/437 (23%), Positives = 165/437 (37%), Gaps = 42/437 (9%)
Query: 159 PAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAA 218
PAA + + AA + VSPA F V P S + VP +TA+VTS P A+
Sbjct: 443 PAASPEISPEVCPAASTVVSPAV-FSVVSPASSAVLPAVSLEVP-LTASVTS----PKAS 496
Query: 219 PPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVAR 278
P P P V ++ AD T +TAS S +V
Sbjct: 497 PVTSPAAAFPTASPANKDVSSF-LETTADVEEITGEGLTASGSGDVMRRRIATPEEVRLP 555
Query: 279 RESGGRPIKPPKKDLE--DGEVPQHA--GKKGK-LSEHLRYCDSILREMLSKKHAAYAWP 333
+ G R KK GE + GK+ K E ++Y + + ++H +++
Sbjct: 556 LQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRNVVHSVRREHFSFS-- 613
Query: 334 FYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPP 393
+ + D+ + P L V+ + E P R N K
Sbjct: 614 -------PRMPVGDFFEERDTPEGLQWVQ--LSAEEIPSRIQAITGKRGRPRNTEKAKTK 664
Query: 394 DHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSS 453
+ V R + P + P+ A+ + + E+ + + S
Sbjct: 665 EVPKVKRGR----------GRPPKVKITELLNKTDNRPLKKLEAQETLNEEDKAKIAKSK 714
Query: 454 DSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEK-EKHK 512
++ R E Q ++ A + K K+KE K+K K +K+K K K EK K
Sbjct: 715 KKMRQKVQR-GECQTTIQGQ----ARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLK 769
Query: 513 VKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPM 572
K + EKK KV K+ K PA KA+ T R+L++ +Q + ++ E + +
Sbjct: 770 EKVKREKKEKVKMKEKEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCL 829
Query: 573 SYDEKRQLSLDINRLPG 589
+ Q D +R+PG
Sbjct: 830 T---DHQPLPDFSRVPG 843
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 71.2 bits (173), Expect = 3e-12
Identities = 40/122 (32%), Positives = 66/122 (54%), Gaps = 13/122 (10%)
Query: 23 PPEVSN-----PSKPGRKTNQLQYMQN------VVVKTLWKHQFAWPFYQPVDAIKLNLP 71
PPE+S+ P + +KT L + + V+ + H+ +WPF +PVD + P
Sbjct: 412 PPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVD--ESYAP 469
Query: 72 DYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEK 131
+Y++IIK PMD+ +++K+L Y + E + D TMF NC YN + + M+ LE+
Sbjct: 470 NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLER 529
Query: 132 IF 133
F
Sbjct: 530 CF 531
Score = 63.5 bits (153), Expect = 6e-10
Identities = 41/131 (31%), Positives = 62/131 (47%), Gaps = 9/131 (6%)
Query: 288 PPKKDLEDGEVPQHAGKKGK----LSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEAL 343
PP+ D P KK K L + +L + + K + WPF +PVD
Sbjct: 412 PPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDS---WPFLEPVDESYA 468
Query: 344 ELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARK 403
+Y+ IIK PMD+S++++K++G Y + F D++ MF NC KYN E M+
Sbjct: 469 P--NYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDN 526
Query: 404 LQDVFEMRFAK 414
L+ F K
Sbjct: 527 LERCFHRAMMK 537
Score = 32.7 bits (73), Expect = 1.2
Identities = 41/195 (21%), Positives = 88/195 (45%), Gaps = 19/195 (9%)
Query: 502 KDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASAS- 560
++ E +K + + K+ P K+ Q++ ++K + A + G Q
Sbjct: 182 RESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQG 241
Query: 561 -----YDSEEEEEGLPMSYDEKRQL-SLDINRLPGEK-LGRVVHIIQSR----EPSLRDS 609
+EEE + S+ E+ L + +L E L + ++I + + + +
Sbjct: 242 TWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAEL 301
Query: 610 NPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEE----LAQEKK 665
+P + D ++KP +++ E V + ++K++RK + A K+E L +E+K
Sbjct: 302 HPRWMS-DHLSIKP--VKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERK 358
Query: 666 KELEKRLQDVSGQLS 680
+ELE++++ V G S
Sbjct: 359 RELEEKVKAVEGMCS 373
>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
sapiens]
Length = 1826
Score = 71.2 bits (173), Expect = 3e-12
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 14/160 (8%)
Query: 42 MQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASEC 101
+ N+V + + +WPF+ PV+ K +PDY+K+I NP+D+ TI+K + + Y S
Sbjct: 1530 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESF 1587
Query: 102 MQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAA 161
+ D N + N YN P AQ + I Q + + + +L K
Sbjct: 1588 LDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQL---------EKDIC 1638
Query: 162 GAQSAGTQQVAAVSSVSPAT--PFQSVPPTVSQTPVIAAT 199
A+ A ++ A + S+ P T P+ S PP + T +T
Sbjct: 1639 TAKEAALEE-AELESLDPMTPGPYTSQPPDMYDTNTSLST 1677
Score = 58.2 bits (139), Expect = 3e-08
Identities = 47/216 (21%), Positives = 97/216 (44%), Gaps = 10/216 (4%)
Query: 318 ILREMLSKKHAAY--AWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQG 375
IL ++++K A +WPF+ PV+ + + DY+ +I +P+DL T+++ + +Y +
Sbjct: 1529 ILDNIVTQKMMAVPDSWPFHHPVNKKFVP--DYYKMIVNPVDLETIRKNISKHKYQSRES 1586
Query: 376 FAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE--PVEAPALPAPAAPMV 433
F DV L+ +N KYN P+ + A+++ ++ + + +E A A +
Sbjct: 1587 FLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQLEKDICTAKEAALE 1646
Query: 434 SKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKE 493
ES S D + T L+ ++ E ++ P+K+
Sbjct: 1647 EAELESLDPMTPGPYTSQPPDMYDTN-TSLSTSRDASVFQDESNLSVLDISTATPEKQMC 1705
Query: 494 KKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQ 529
+ + ++D + + E + +EE+ K PPA +
Sbjct: 1706 QGQGRLGEEDSDVDVEGYD---DEEEDGKPKPPAPE 1738
Score = 52.8 bits (125), Expect = 1e-06
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Query: 333 PFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNP 392
PF+ PV+A+ ++ DY+ II PMDL T++ + YP + F + L+ N YN
Sbjct: 1423 PFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
Query: 393 PDHEVVAMARKLQDVFEMRFAKMPDE 418
P H + +++ + D+ + + + D+
Sbjct: 1481 PKHSLTQISQSMLDLCDEKLKEKEDK 1506
Score = 43.5 bits (101), Expect = 7e-04
Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Query: 58 PFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNK 117
PF+ PV+A + DY+KII PMD+ T+++ + Y S E + + N YN
Sbjct: 1423 PFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
Query: 118 PTDDIVLMAQALEKIFLQKVAQ 139
P + ++Q++ + +K+ +
Sbjct: 1481 PKHSLTQISQSMLDLCDEKLKE 1502
>gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]
Length = 1235
Score = 70.5 bits (171), Expect = 5e-12
Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 9/150 (6%)
Query: 38 QLQYMQNVVVKTLWK----HQFAWPFYQPV-DAIKLNLPDYHKIIKNPMDMGTIKKRLEN 92
Q Q + + +W+ H++A F QPV D I P YH I++ PMD+ TIKK +EN
Sbjct: 707 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 763
Query: 93 NYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAP 152
S +E +D MF N +YN D+ MA +++ L+++ Q ++ ++ +
Sbjct: 764 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQL-IMQTSE 822
Query: 153 KGKGRKPAAGAQSAGTQQVAAVSSVSPATP 182
G K G S Q + SV +P
Sbjct: 823 SGISAKSLRGRDSTRKQDASEKDSVPMGSP 852
Score = 60.1 bits (144), Expect = 7e-09
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 4/122 (3%)
Query: 330 YAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYK 389
YA F +PV + YH I++ PMDLST+K+ ++ F D+ LMF N
Sbjct: 728 YANVFLQPVTDDIAP--GYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVM 785
Query: 390 YNPPDHEVVAMARKLQ-DVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSS 448
YN DH+V MA ++Q DV E + + + + +A + +G +S+R + S
Sbjct: 786 YNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSL-RGRDSTRKQDASEK 844
Query: 449 DS 450
DS
Sbjct: 845 DS 846
Score = 54.3 bits (129), Expect = 4e-07
Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 308 LSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDG 367
+ +HL + ++L ++ PF KPV + Y D++K PMDL+++KR +
Sbjct: 1102 VQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSER--QAPGYKDVVKRPMDLTSLKRNLSK 1159
Query: 368 REYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQ 405
F D+ LMF N YN DH V MA +++
Sbjct: 1160 GRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMR 1197
Score = 50.8 bits (120), Expect = 4e-06
Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query: 46 VVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDF 105
V K + H+F+ PF +PV + P Y ++K PMD+ ++K+ L + ++ ++D
Sbjct: 1115 VWKMIASHRFSSPFLKPVS--ERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDL 1172
Query: 106 NTMFTNCYIYNKPTDDIVLMAQALEKIFLQKV 137
MF N +YN + MA + + L+++
Sbjct: 1173 MLMFQNAVMYNDSDHHVYHMAVEMRREVLEQI 1204
>gi|34452705 bromodomain containing 8 isoform 1 [Homo sapiens]
Length = 951
Score = 70.5 bits (171), Expect = 5e-12
Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 9/150 (6%)
Query: 38 QLQYMQNVVVKTLWK----HQFAWPFYQPV-DAIKLNLPDYHKIIKNPMDMGTIKKRLEN 92
Q Q + + +W+ H++A F QPV D I P YH I++ PMD+ TIKK +EN
Sbjct: 780 QAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIA---PGYHSIVQRPMDLSTIKKNIEN 836
Query: 93 NYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAP 152
S +E +D MF N +YN D+ MA +++ L+++ Q ++ ++ +
Sbjct: 837 GLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQL-IMQTSE 895
Query: 153 KGKGRKPAAGAQSAGTQQVAAVSSVSPATP 182
G K G S Q + SV +P
Sbjct: 896 SGISAKSLRGRDSTRKQDASEKDSVPMGSP 925
Score = 60.1 bits (144), Expect = 7e-09
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 4/122 (3%)
Query: 330 YAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYK 389
YA F +PV + YH I++ PMDLST+K+ ++ F D+ LMF N
Sbjct: 801 YANVFLQPVTDDIAP--GYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVM 858
Query: 390 YNPPDHEVVAMARKLQ-DVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSS 448
YN DH+V MA ++Q DV E + + + + +A + +G +S+R + S
Sbjct: 859 YNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSL-RGRDSTRKQDASEK 917
Query: 449 DS 450
DS
Sbjct: 918 DS 919
Score = 33.5 bits (75), Expect = 0.71
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 174 VSSVSPAT--PFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVP 231
+ S SP P + PT + TP + VTS P P PP A P+ P
Sbjct: 189 IDSASPGGDYPLGDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTP 248
Query: 232 PTPPVVKKKGVKRKADTTTPTTSAI 256
T +KK + +KA TP S +
Sbjct: 249 VTDDSPQKKMLGQKA---TPPPSPL 270
>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
Length = 1872
Score = 70.1 bits (170), Expect = 7e-12
Identities = 43/154 (27%), Positives = 72/154 (46%), Gaps = 14/154 (9%)
Query: 42 MQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASEC 101
+ N+V + + +WPF+ PV+ K +PDY+K+I NPMD+ TI+K + + Y S
Sbjct: 1511 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESF 1568
Query: 102 MQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAA 161
+ D N + N YN P AQ + + Q + + + +L K
Sbjct: 1569 LDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQL---------EKDIC 1619
Query: 162 GAQSAGTQQVAAVSSVSPAT--PFQSVPPTVSQT 193
A+ A ++ A + S+ P T P+ PP + T
Sbjct: 1620 TAKEAALEE-AELESLDPMTPGPYTPQPPDLYDT 1652
Score = 59.7 bits (143), Expect = 9e-09
Identities = 29/92 (31%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Query: 318 ILREMLSKKHAAY--AWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQG 375
IL ++++K A +WPF+ PV+ + + DY+ +I +PMDL T+++ + +Y +
Sbjct: 1510 ILDNIVTQKMMAVPDSWPFHHPVNKKFVP--DYYKVIVNPMDLETIRKNISKHKYQSRES 1567
Query: 376 FAADVRLMFSNCYKYNPPDHEVVAMARKLQDV 407
F DV L+ +N KYN P+ + A+++ +V
Sbjct: 1568 FLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1599
Score = 57.4 bits (137), Expect = 5e-08
Identities = 29/103 (28%), Positives = 56/103 (54%), Gaps = 5/103 (4%)
Query: 316 DSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQG 375
+SI+ +M + +PF+ PV+A+ ++ DY+ II PMDL T++ + R YP +
Sbjct: 1390 ESIINDM---RDLPNTYPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSREE 1444
Query: 376 FAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 418
F + L+ N YN P H + +++ + D+ + + + D+
Sbjct: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDK 1487
Score = 45.4 bits (106), Expect = 2e-04
Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
Query: 57 WPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYN 116
+PF+ PV+A + DY+KII PMD+ T+++ + Y S E + + N YN
Sbjct: 1403 YPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYN 1460
Query: 117 KPTDDIVLMAQALEKIFLQKVAQ 139
P + ++Q++ + +K+ +
Sbjct: 1461 GPKHSLTQISQSMLDLCDEKLKE 1483
>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
Length = 1893
Score = 70.1 bits (170), Expect = 7e-12
Identities = 43/154 (27%), Positives = 72/154 (46%), Gaps = 14/154 (9%)
Query: 42 MQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASEC 101
+ N+V + + +WPF+ PV+ K +PDY+K+I NPMD+ TI+K + + Y S
Sbjct: 1532 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESF 1589
Query: 102 MQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAA 161
+ D N + N YN P AQ + + Q + + + +L K
Sbjct: 1590 LDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQL---------EKDIC 1640
Query: 162 GAQSAGTQQVAAVSSVSPAT--PFQSVPPTVSQT 193
A+ A ++ A + S+ P T P+ PP + T
Sbjct: 1641 TAKEAALEE-AELESLDPMTPGPYTPQPPDLYDT 1673
Score = 59.7 bits (143), Expect = 9e-09
Identities = 29/92 (31%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Query: 318 ILREMLSKKHAAY--AWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQG 375
IL ++++K A +WPF+ PV+ + + DY+ +I +PMDL T+++ + +Y +
Sbjct: 1531 ILDNIVTQKMMAVPDSWPFHHPVNKKFVP--DYYKVIVNPMDLETIRKNISKHKYQSRES 1588
Query: 376 FAADVRLMFSNCYKYNPPDHEVVAMARKLQDV 407
F DV L+ +N KYN P+ + A+++ +V
Sbjct: 1589 FLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1620
Score = 57.4 bits (137), Expect = 5e-08
Identities = 29/103 (28%), Positives = 56/103 (54%), Gaps = 5/103 (4%)
Query: 316 DSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQG 375
+SI+ +M + +PF+ PV+A+ ++ DY+ II PMDL T++ + R YP +
Sbjct: 1411 ESIINDM---RDLPNTYPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSREE 1465
Query: 376 FAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 418
F + L+ N YN P H + +++ + D+ + + + D+
Sbjct: 1466 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDK 1508
Score = 45.4 bits (106), Expect = 2e-04
Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
Query: 57 WPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYN 116
+PF+ PV+A + DY+KII PMD+ T+++ + Y S E + + N YN
Sbjct: 1424 YPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYN 1481
Query: 117 KPTDDIVLMAQALEKIFLQKVAQ 139
P + ++Q++ + +K+ +
Sbjct: 1482 GPKHSLTQISQSMLDLCDEKLKE 1504
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 69.7 bits (169), Expect = 9e-12
Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 16/134 (11%)
Query: 339 DAEALELHDYHDIIKHPMDLSTVKRKM--DGREYPDAQGFAADVRLMFSNCYKYNPPDHE 396
D L + DY+ IIK+PMDLST+K+++ D Y + F AD RL+F NC ++N PD E
Sbjct: 926 DPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSE 985
Query: 397 VVAMARKLQDVFEMRFAKM-PDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDS 455
V KL++ FE + P++ P + S + SD D
Sbjct: 986 VANAGIKLENYFEELLKNLYPEKRFPKPEF-------------RNESEDNKFSDDSDDDF 1032
Query: 456 EEERATRLAELQEQ 469
+ R RL ++E+
Sbjct: 1033 VQPRKKRLKSIEER 1046
Score = 68.6 bits (166), Expect = 2e-11
Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 5/97 (5%)
Query: 50 LWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNY--YWSASECMQDFNT 107
L+ H+ + F PV L +PDY+KIIKNPMD+ TIKKRL+ +Y Y + + DF
Sbjct: 915 LYCHEMSLAFQDPVP---LTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRL 971
Query: 108 MFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEE 144
+F NC +N+P ++ LE F + + + E+
Sbjct: 972 IFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEK 1008
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 69.7 bits (169), Expect = 9e-12
Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 16/134 (11%)
Query: 339 DAEALELHDYHDIIKHPMDLSTVKRKM--DGREYPDAQGFAADVRLMFSNCYKYNPPDHE 396
D L + DY+ IIK+PMDLST+K+++ D Y + F AD RL+F NC ++N PD E
Sbjct: 892 DPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSE 951
Query: 397 VVAMARKLQDVFEMRFAKM-PDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDS 455
V KL++ FE + P++ P + S + SD D
Sbjct: 952 VANAGIKLENYFEELLKNLYPEKRFPKPEF-------------RNESEDNKFSDDSDDDF 998
Query: 456 EEERATRLAELQEQ 469
+ R RL ++E+
Sbjct: 999 VQPRKKRLKSIEER 1012
Score = 68.6 bits (166), Expect = 2e-11
Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 5/97 (5%)
Query: 50 LWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNY--YWSASECMQDFNT 107
L+ H+ + F PV L +PDY+KIIKNPMD+ TIKKRL+ +Y Y + + DF
Sbjct: 881 LYCHEMSLAFQDPVP---LTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRL 937
Query: 108 MFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEE 144
+F NC +N+P ++ LE F + + + E+
Sbjct: 938 IFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEK 974
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 69.3 bits (168), Expect = 1e-11
Identities = 80/334 (23%), Positives = 139/334 (41%), Gaps = 47/334 (14%)
Query: 429 AAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKP 488
A+ KG S+ +S +S+ + + +E+ + E +E+ A + L + KP
Sbjct: 1244 ASSTTPKGNSSNGNSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKEKP 1303
Query: 489 KKK---KEKKEKEKK----KKDKEKEKEKHKVKAEEEKKAKVAPPAK-QAQQKKAPAKKA 540
K++ K++K +E K K DKEKEK K + KA++EK P A+ ++ Q++ K+
Sbjct: 1304 KEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEP 1363
Query: 541 NSTTTAGRQLK-----KGGKQA--SASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLG 593
+ +++K KGG++ S S S +P E+++ +D + P
Sbjct: 1364 SRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSHSST 1423
Query: 594 RVVHIIQSREPSLRD---------SNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKP 644
+I+ +E S + S E E+D + L + R ER K +K+RK
Sbjct: 1424 VKDSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKR 1483
Query: 645 FSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPAR------------KEKPG 692
++ + E +L KR ++ +G + SK + KEK
Sbjct: 1484 DHSNNDR-----------EVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKEKNK 1532
Query: 693 SAPSGGPSRLSSSSSSESGSSSSSGSSSDSSDSE 726
S SG S S + SS G D E
Sbjct: 1533 SKSSGKEKGSDSFKSEKMDKISSGGKKESRHDKE 1566
Score = 62.8 bits (151), Expect = 1e-09
Identities = 75/326 (23%), Positives = 131/326 (40%), Gaps = 44/326 (13%)
Query: 433 VSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKK 492
V+K + ++ S+ +SGS+ ++ + + +E+ K E+ A + K K
Sbjct: 1241 VNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGK 1300
Query: 493 EKKEKEK--------------KKKDKEKEKEKHKVKAEEEKKAKVAPPAK-QAQQKKAPA 537
EK ++E+ K DKEKEK K + KA++EK P A+ ++ Q++
Sbjct: 1301 EKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQERERE 1360
Query: 538 KKANSTTTAGRQLK-----KGGKQ--ASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGE 590
K+ + +++K KGG++ S S S +P E+++ +D + P
Sbjct: 1361 KEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTHPSPSH 1420
Query: 591 KLGRVVHIIQSREPSLR---------DSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQ 641
+I+ +E S + S E E+D + L + R ER K +K+
Sbjct: 1421 SSTVKDSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKE 1480
Query: 642 RKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARK--EKPGSAPSGGP 699
RK + +E +L KR ++ +G + SK + E P
Sbjct: 1481 RK-----------RDHSNNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPYPNEKDKE 1529
Query: 700 SRLSSSSSSESGSSSSSGSSSDSSDS 725
S SS E GS S D S
Sbjct: 1530 KNKSKSSGKEKGSDSFKSEKMDKISS 1555
Score = 42.7 bits (99), Expect = 0.001
Identities = 76/317 (23%), Positives = 122/317 (38%), Gaps = 46/317 (14%)
Query: 421 EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL 480
+ P A A+ G S SS S+S S S +EE +R Q +KAV++ A
Sbjct: 1190 DPPPRNAVASVQNGPGGGPSSSSIGSASKSDESSTEETDKSR-ERSQCGVKAVNK---AS 1245
Query: 481 SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA 540
S P K K KE +KEK K K +E+K +K PA
Sbjct: 1246 STTP--KGNSSNGNSGSNSNKAVKENDKEKGKEKEKEKK-------------EKTPA--- 1287
Query: 541 NSTTTAGRQLKKGGKQ------ASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGR 594
TT R L K GK+ + + E +E P S EK + + + EK
Sbjct: 1288 --TTPEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFKKE-EKAKDEKFKT 1344
Query: 595 VVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAA 654
V +S+ R+ + P+ R++ + +KS K + SG ++
Sbjct: 1345 TVPNAESKSTQEREREKE----------PSRERDIAKEMKSKENVKGGEKTPVSGSLKSP 1394
Query: 655 KSKEELAQEKKKELEKRLQ-DVSGQLSSSKKPARKE-KPGSAP---SGGPSRLSSSSSSE 709
+ ++ + ++++ +++ S SS+ K + E K SA + P LS S E
Sbjct: 1395 VPRSDIPEPEREQKRRKIDTHPSPSHSSTVKDSLIELKESSAKLYINHTPPPLSKSKERE 1454
Query: 710 SGSSSSSGSSSDSSDSE 726
S S + E
Sbjct: 1455 MDKKDLDKSRERSRERE 1471
Score = 33.9 bits (76), Expect = 0.55
Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 1/77 (1%)
Query: 481 SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA 540
S++P P ++ KEK K K KEK K+E+ K + K+ KK
Sbjct: 1514 SESPCESPYPNEKDKEKNKSKS-SGKEKGSDSFKSEKMDKISSGGKKESRHDKEKIEKKE 1572
Query: 541 NSTTTAGRQLKKGGKQA 557
++ G++ KK K +
Sbjct: 1573 KRDSSGGKEEKKHHKSS 1589
Score = 30.8 bits (68), Expect = 4.6
Identities = 38/253 (15%), Positives = 105/253 (41%), Gaps = 18/253 (7%)
Query: 437 AESSRSSEESSSDSGSSD-SEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKK 495
++S++ E S D ++E ++ + E+ + + ++ + +P+++++++
Sbjct: 1351 SKSTQEREREKEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRR 1410
Query: 496 EKEKKKKDKEKEKEKHKVKAEEEKKAKV-----APPAKQAQQKKAPAKKANSTTTAGRQL 550
+ + K + +E AK+ PP ++++++ K + + R+
Sbjct: 1411 KIDTHPSPSHSSTVKDSLIELKESSAKLYINHTPPPLSKSKEREMDKKDLDKSRERSRER 1470
Query: 551 KKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSN 610
+K D ++ +E + R++ D+ + E+ G + E
Sbjct: 1471 EKK--------DEKDRKERKRDHSNNDREVPPDLTKRRKEENGTMGVSKHKSESPCESPY 1522
Query: 611 PDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEK 670
P+E + + K + + KS ++ S+ GKK++ KE++ +++K++
Sbjct: 1523 PNEKDKEKNKSKSSGKEKGSDSFKS----EKMDKISSGGKKESRHDKEKIEKKEKRDSSG 1578
Query: 671 RLQDVSGQLSSSK 683
++ SS K
Sbjct: 1579 GKEEKKHHKSSDK 1591
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 68.6 bits (166), Expect = 2e-11
Identities = 47/166 (28%), Positives = 73/166 (43%), Gaps = 7/166 (4%)
Query: 256 ITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGE-VPQHAGKKGKLSEHLRY 314
I S PP ++ +P PP D E E V Q + S L+
Sbjct: 1288 IRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQK 1347
Query: 315 CDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQ 374
C+ IL +++ + ++WPF +PV + E DY+D+I HPMD TV+ K Y Q
Sbjct: 1348 CEEILHKIVKYR---FSWPFREPVTRD--EAEDYYDVITHPMDFQTVQNKCSCGSYRSVQ 1402
Query: 375 GFAADVRLMFSNCYKYN-PPDHEVVAMARKLQDVFEMRFAKMPDEP 419
F D++ +F+N YN H + M + Q + + +P P
Sbjct: 1403 EFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALLHKHLPGHP 1448
Score = 55.1 bits (131), Expect = 2e-07
Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 3/83 (3%)
Query: 34 RKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENN 93
R++ +LQ + ++ K + K++F+WPF +PV + DY+ +I +PMD T++ +
Sbjct: 1340 RQSLELQKCEEILHKIV-KYRFSWPFREPVTRDEAE--DYYDVITHPMDFQTVQNKCSCG 1396
Query: 94 YYWSASECMQDFNTMFTNCYIYN 116
Y S E + D +FTN +YN
Sbjct: 1397 SYRSVQEFLTDMKQVFTNAEVYN 1419
Score = 38.5 bits (88), Expect = 0.022
Identities = 51/217 (23%), Positives = 86/217 (39%), Gaps = 54/217 (24%)
Query: 414 KMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAV 473
++PD + PA A S+G + S S+ SD EE
Sbjct: 1220 EVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESDEEE---------------- 1263
Query: 474 HEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQK 533
E++E+E++++D E + + + K V PPA A+
Sbjct: 1264 -------------------EEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPA--ARSG 1302
Query: 534 KAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLG 593
+ P KK +ST ++ +A D+E +E L +RQ SL++ + E L
Sbjct: 1303 RRPGKKPHST-------RRSQPKAPPVDDAEVDELVLQTKRSSRRQ-SLELQKCE-EILH 1353
Query: 594 RVVHIIQS---REPSLRDSNPDEIEI-----DFETLK 622
++V S REP RD D ++ DF+T++
Sbjct: 1354 KIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQ 1390
Score = 33.9 bits (76), Expect = 0.55
Identities = 68/279 (24%), Positives = 109/279 (39%), Gaps = 27/279 (9%)
Query: 411 RFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESS-SDSGSSDSEEERATRLAELQEQ 469
R + P + + AL A +K E RS+ S + S E+RA EL+
Sbjct: 462 RTSSKPHKHLPPAALHLIAYYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSL 521
Query: 470 LKAVHEQLAALSQAPVNKPKKKKE---KKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPP 526
++ +E L + +++KE KK +E KKK KEK KE+ + + E + +
Sbjct: 522 VQKRYELLEHKKRWASMSEEQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYE 581
Query: 527 AKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINR 586
++ K PA + T G + S LP + +SL +
Sbjct: 582 DQELTGKNLPAFRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSL-MEA 640
Query: 587 LPGEK-----LGRVVHIIQSREPSLRDSNPDEIEIDFETLK------PTTLRELERYVKS 635
L +K L RV+ I+ L+ DEI D+ L P TL + V+
Sbjct: 641 LSADKGGFLYLNRVLVIL------LQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRL 694
Query: 636 CL-----QKKQRKPFSASGKKQAAKSKEELAQEKKKELE 669
CL Q++ + K AA E+ E ++LE
Sbjct: 695 CLRRSDVQEESEGSDTDDNKDSAAFEDNEVQDEFLEKLE 733
Score = 30.8 bits (68), Expect = 4.6
Identities = 54/261 (20%), Positives = 93/261 (35%), Gaps = 16/261 (6%)
Query: 449 DSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEK 508
+S +S S EE + ++ K P KP K +K K K +
Sbjct: 355 NSKNSKSPEEHLEEMMKMMSPNKLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNG 414
Query: 509 EKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEE 568
+K ++ KK P K Q K T + G + S+
Sbjct: 415 QKSTGNSKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSKPHKHLPPA 474
Query: 569 GLPM-SYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDE----IEIDFETL-- 621
L + +Y ++ + D + + ++ S + R P+E ++ +E L
Sbjct: 475 ALHLIAYYKENKDREDKRSALSCVISKTARLLSSED---RARLPEELRSLVQKRYELLEH 531
Query: 622 KPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSS 681
K E K L+KK+ + KK K+KE +E + LEK+ + +L+
Sbjct: 532 KKRWASMSEEQRKEYLKKKREE----LKKKLKEKAKERREKEMLERLEKQKRYEDQELTG 587
Query: 682 SKKPARKEKPGSAPSGGPSRL 702
PA + P G P+ L
Sbjct: 588 KNLPAFRLV--DTPEGLPNTL 606
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 67.4 bits (163), Expect = 4e-11
Identities = 82/348 (23%), Positives = 138/348 (39%), Gaps = 54/348 (15%)
Query: 416 PDEPVEAPALPAPAAPMVS------KGAESSRSSEESSSDSGSSDSEEERATRL-AELQE 468
P P E + P PA+P + K AE +SE + + E+ T + E +E
Sbjct: 292 PPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKE 351
Query: 469 QLKAVHEQLAAL---SQAPVNKPKKKKEKK------EKEKKKKDKEKEKEKHKVKAEEEK 519
KA + + +QA K +KK++ K E E+ K K+++KEKH A+ K
Sbjct: 352 PGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPK 411
Query: 520 KAKVAPPAKQAQ---------------QKKAPAKKANSTTTAGRQ---LKKGGKQASASY 561
K P KQ + +K P KK TT Q +K GK +S
Sbjct: 412 KEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILK 471
Query: 562 DSEE---EEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDF 618
D E +EE +P S EK + EK+ + ++ + P L+ ++ E
Sbjct: 472 DKEPIKGKEEKVPASLKEK-----EPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQI 526
Query: 619 ETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEK--KKELEKRLQDVS 676
+ + E + K + K ++ +++ K + + EK K + K+ +
Sbjct: 527 KKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHRE 586
Query: 677 GQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSSDSSD 724
+ S K +KP P G +S +ESG + S +S +
Sbjct: 587 REPPSIK----TDKPKPTPKG------TSEVTESGKKKTEISEKESKE 624
Score = 65.5 bits (158), Expect = 2e-10
Identities = 68/284 (23%), Positives = 123/284 (43%), Gaps = 40/284 (14%)
Query: 442 SSEESSSDSGSSDSE----EERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEK--- 494
SSE+ D G D++ +E R E+ + E+ Q V +K+K K
Sbjct: 115 SSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKV 174
Query: 495 KEKEK-------KKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAG 547
+EKEK K+K ++KEK + K A+E+KKAK A +++ +K+ K
Sbjct: 175 REKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTA 234
Query: 548 RQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLS-----LDI----NRLPGEKLGRVVHI 598
++K+ K S + E++E+ +++K Q + +DI + PG+
Sbjct: 235 AKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQS-----PA 289
Query: 599 IQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKE 658
I P+ + S P E K ++ E+ V S +KK+++ +K+ A E
Sbjct: 290 IPPPLPTEQASRPTPASPALEE-KEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVE 348
Query: 659 ELAQEKKKELEKRLQDVSGQLSS-----------SKKPARKEKP 691
+ K E ++ ++ Q ++ +KKPA E+P
Sbjct: 349 KKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQP 392
Score = 39.3 bits (90), Expect = 0.013
Identities = 65/313 (20%), Positives = 122/313 (38%), Gaps = 66/313 (21%)
Query: 441 RSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKK 500
+ E+ + E++AT +++++ K + LA Q +K +EK +KE K
Sbjct: 165 KEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAK-EQKKAKTAEKSEEKTKKEVK 223
Query: 501 ---------------------KKDKEKE-KEKHKVKAEEEK------------------- 519
K KEKE KEK V E+K
Sbjct: 224 GGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLK 283
Query: 520 --KAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEK 577
++ PP +Q P + + + KK K+ ++ +E+E+ + +
Sbjct: 284 PGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKED---IKKKSE 340
Query: 578 RQLSLDINRL-PGE----KLGRVVHIIQS---REPSLRDSNPDEIEIDFETLKPTTLREL 629
++ ++D+ + PG+ K G V Q+ ++ DS + + E K +
Sbjct: 341 KETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKK 400
Query: 630 ERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEK------KKELEKRLQDVSGQLSSSK 683
E++V+ K +K S KQ K+K E A+E+ KK + + ++ + + +
Sbjct: 401 EKHVEPA--KSPKKEHSVPSDKQ-VKAKTERAKEEIGAVSIKKAVPGKKEEKT--TKTVE 455
Query: 684 KPARKEKPGSAPS 696
+ RKEK G S
Sbjct: 456 QEIRKEKSGKTSS 468
Score = 39.3 bits (90), Expect = 0.013
Identities = 91/403 (22%), Positives = 148/403 (36%), Gaps = 79/403 (19%)
Query: 215 PAAAPPPPATPIVPVVPPTPPVVKKKGVKRKAD--TTTPT--------------TSAITA 258
PA PP P P +P + +K+G K+KA+ T+ T +AI
Sbjct: 288 PAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDV 347
Query: 259 SRSESPPPLSDPKQAKVVARRESGGR---PIKPPKKDLEDGEVPQHAGKK-GKLSEHLRY 314
+ E P S+ KQ V ++ + + KK + EV Q GKK K +H+
Sbjct: 348 EKKE-PGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEP 406
Query: 315 CDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDG-REYPDA 373
S +E ++ P K V A+ + K + ++K+ + G +E
Sbjct: 407 AKSPKKE--------HSVPSDKQVKAKT-------ERAKEEIGAVSIKKAVPGKKEEKTT 451
Query: 374 QGFAADVRL----MFSNCYKYNPP---DHEVVAMARKLQDVFEMRFAKM----------- 415
+ ++R S+ K P E V + K ++ + KM
Sbjct: 452 KTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKP 511
Query: 416 -----PDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQL 470
E P + A P +S+ + + + S EE+ + Q+
Sbjct: 512 PQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLK------QV 565
Query: 471 KAVHEQLAALSQAPVNKPKKKKEKKEKEKK--KKDKEKEKEKHKVKAEEEKKAKVAPPAK 528
KAV + + KP KK E +E+E K DK K K + E K K K
Sbjct: 566 KAV-----TIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEK 620
Query: 529 QAQQK---KAPAKKANSTTTAGRQL---KKGGKQASASYDSEE 565
++++K K ++ ST QL K K A S D E+
Sbjct: 621 ESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVED 663
>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform 2
[Homo sapiens]
Length = 1214
Score = 67.4 bits (163), Expect = 4e-11
Identities = 97/402 (24%), Positives = 166/402 (41%), Gaps = 46/402 (11%)
Query: 334 FYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPP 393
F +PV E+ DY D IK PMD T+K+ ++ Y + F D L+ SNC KYN
Sbjct: 653 FSEPVPLS--EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAK 710
Query: 394 DHEVVAMARKL--QDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSG 451
D A +L Q +R A+ E + P G E++ +E++
Sbjct: 711 DTIFYRAAVRLREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA----- 765
Query: 452 SSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKH 511
+EEER L E Q+ L V EQL L + +++ K+ + ++ K +KE
Sbjct: 766 ---AEEERLV-LLENQKHL-PVEEQLKLLLER-LDEVNASKQSVGRSRRAKMIKKE---- 815
Query: 512 KVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLP 571
+ A K A + ++ P+ + S T K G+ SA+ +S +E
Sbjct: 816 -MTALRRKLAHQRETGRDGPERHGPSSR-GSLTPHPAACDKDGQTDSAAEESSSQE---- 869
Query: 572 MSYDEKRQLSLDINRLPGEKLGRVVHIIQSRE------PSLRDSNPDEIEIDFETLK--P 623
+ L +++ P ++GR ++ S++ P R P + T
Sbjct: 870 ----TSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRESQMTPSHGG 925
Query: 624 TTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSK 683
+ + + + S L++++R G+ S + +K E + + + S
Sbjct: 926 SPVGPPQLPIMSSLRQRKR------GRSPRPSSSSDSDSDKSTE-DPPMDLPANGFSGGN 978
Query: 684 KPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSSDSSDS 725
+P +K S SSS SES SSSSS ++SD + +
Sbjct: 979 QPVKKS--FLVYRNDCSLPRSSSDSESSSSSSSSAASDRTST 1018
Score = 43.1 bits (100), Expect = 0.001
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Query: 59 FYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYN 116
F +PV ++ PDY IK PMD T+K+ LE Y + + +DFN + +NC YN
Sbjct: 653 FSEPVPLSEV--PDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYN 708
Score = 32.3 bits (72), Expect = 1.6
Identities = 40/152 (26%), Positives = 58/152 (38%), Gaps = 22/152 (14%)
Query: 150 PAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVT 209
P+ +G A G AA S S T + + P +S TP A V T+ +
Sbjct: 839 PSSRGSLTPHPAACDKDGQTDSAAEESSSQETS-KGLGPNMSSTP---AHEVGRRTSVLF 894
Query: 210 SVPVPPAAAPP-----PPA------TPI---VPVVPPTPPVVKKKGVKRKADTTTPTTSA 255
S P A PP PP TP PV PP P++ +++ + P++S
Sbjct: 895 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSS- 953
Query: 256 ITASRSESPPPLSDPKQAKVVARRESGGRPIK 287
S S+S DP G +P+K
Sbjct: 954 ---SDSDSDKSTEDPPMDLPANGFSGGNQPVK 982
Score = 31.2 bits (69), Expect = 3.5
Identities = 27/107 (25%), Positives = 37/107 (34%), Gaps = 17/107 (15%)
Query: 423 PALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQ--------------- 467
P P KG +S ++++S S S S S A+ Q
Sbjct: 52 PPQQTPLRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRIS 111
Query: 468 --EQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHK 512
+ L V E A +AP N K+ + K K K KEK K
Sbjct: 112 IFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRK 158
>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform 1
[Homo sapiens]
Length = 1220
Score = 67.0 bits (162), Expect = 6e-11
Identities = 94/392 (23%), Positives = 162/392 (41%), Gaps = 44/392 (11%)
Query: 344 ELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARK 403
E+ DY D IK PMD T+K+ ++ Y + F D L+ SNC KYN D A +
Sbjct: 667 EVPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVR 726
Query: 404 L--QDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERAT 461
L Q +R A+ E + P G E++ +E++ +EEER
Sbjct: 727 LREQGGAVLRQARRQAEKMGIDFETGMHIPHSLAGDEATHHTEDA--------AEEERLV 778
Query: 462 RLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKA 521
L E Q+ L V EQL L + +++ K+ + ++ K +KE + A K A
Sbjct: 779 -LLENQKHL-PVEEQLKLLLER-LDEVNASKQSVGRSRRAKMIKKE-----MTALRRKLA 830
Query: 522 KVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLS 581
+ ++ P+ + S T K G+ SA+ +S +E + L
Sbjct: 831 HQRETGRDGPERHGPSSR-GSLTPHPAACDKDGQTDSAAEESSSQE--------TSKGLG 881
Query: 582 LDINRLPGEKLGRVVHIIQSRE------PSLRDSNPDEIEIDFETLK--PTTLRELERYV 633
+++ P ++GR ++ S++ P R P + T + + + +
Sbjct: 882 PNMSSTPAHEVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPI 941
Query: 634 KSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGS 693
S L++++R G+ S + +K E + + + S +P +K
Sbjct: 942 MSSLRQRKR------GRSPRPSSSSDSDSDKSTE-DPPMDLPANGFSGGNQPVKKS--FL 992
Query: 694 APSGGPSRLSSSSSSESGSSSSSGSSSDSSDS 725
S SSS SES SSSSS ++SD + +
Sbjct: 993 VYRNDCSLPRSSSDSESSSSSSSSAASDRTST 1024
Score = 42.7 bits (99), Expect = 0.001
Identities = 20/47 (42%), Positives = 28/47 (59%)
Query: 70 LPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYN 116
+PDY IK PMD T+K+ LE Y + + +DFN + +NC YN
Sbjct: 668 VPDYLDHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYN 714
Score = 32.3 bits (72), Expect = 1.6
Identities = 40/152 (26%), Positives = 58/152 (38%), Gaps = 22/152 (14%)
Query: 150 PAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVT 209
P+ +G A G AA S S T + + P +S TP A V T+ +
Sbjct: 845 PSSRGSLTPHPAACDKDGQTDSAAEESSSQETS-KGLGPNMSSTP---AHEVGRRTSVLF 900
Query: 210 SVPVPPAAAPP-----PPA------TPI---VPVVPPTPPVVKKKGVKRKADTTTPTTSA 255
S P A PP PP TP PV PP P++ +++ + P++S
Sbjct: 901 SKKNPKTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRSPRPSSS- 959
Query: 256 ITASRSESPPPLSDPKQAKVVARRESGGRPIK 287
S S+S DP G +P+K
Sbjct: 960 ---SDSDSDKSTEDPPMDLPANGFSGGNQPVK 988
Score = 31.2 bits (69), Expect = 3.5
Identities = 27/107 (25%), Positives = 37/107 (34%), Gaps = 17/107 (15%)
Query: 423 PALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQ--------------- 467
P P KG +S ++++S S S S S A+ Q
Sbjct: 52 PPQQTPLRKHKKKGRQSRPANKQSPSPSEVSQSPGREVMSYAQAQRMVEVDLHGRVHRIS 111
Query: 468 --EQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHK 512
+ L V E A +AP N K+ + K K K KEK K
Sbjct: 112 IFDNLDVVSEDEEAPEEAPENGSNKENTETPAATPKSGKHKNKEKRK 158
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,507,896
Number of Sequences: 37866
Number of extensions: 1956357
Number of successful extensions: 65284
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1073
Number of HSP's successfully gapped in prelim test: 1882
Number of HSP's that attempted gapping in prelim test: 21979
Number of HSP's gapped (non-prelim): 22224
length of query: 726
length of database: 18,247,518
effective HSP length: 110
effective length of query: 616
effective length of database: 14,082,258
effective search space: 8674670928
effective search space used: 8674670928
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.