Guide to the Human Genome
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Search of human proteins with 110618253

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110618253 mitochondrial DNA-directed RNA polymerase
precursor [Homo sapiens]
         (1230 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110618253 mitochondrial DNA-directed RNA polymerase precursor...  2490   0.0  
gi|224458301 family with sequence similarity 186, member A [Homo...    39   0.030
gi|221139761 zinc finger protein 853 [Homo sapiens]                    39   0.040
gi|46275820 tetratricopeptide repeat domain 9B [Homo sapiens]          38   0.052
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               35   0.34 
gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Hom...    35   0.34 
gi|39930399 tumor protein p53 inducible nuclear protein 2 [Homo ...    35   0.58 
gi|10092691 tight junction protein 3 [Homo sapiens]                    34   0.75 
gi|210032790 hypothetical protein LOC27146 [Homo sapiens]              34   0.75 
gi|39725952 angiogenic factor VG5Q [Homo sapiens]                      34   0.98 
gi|38158015 mastermind-like 3 [Homo sapiens]                           34   0.98 
gi|151301215 widely-interspaced zinc finger motifs [Homo sapiens]      33   1.3  
gi|118498339 EMI domain containing 2 [Homo sapiens]                    33   1.3  
gi|116292168 KRAB A domain containing 1 [Homo sapiens]                 33   1.7  
gi|124378039 SEC16 homolog A [Homo sapiens]                            32   2.9  
gi|4504465 homeobox B2 [Homo sapiens]                                  32   2.9  
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    32   3.7  
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    32   3.7  
gi|109637771 calpastatin isoform l [Homo sapiens]                      32   3.7  
gi|109637769 calpastatin isoform k [Homo sapiens]                      32   3.7  
gi|109637767 calpastatin isoform j [Homo sapiens]                      32   3.7  
gi|109637765 calpastatin isoform i [Homo sapiens]                      32   3.7  
gi|109637763 calpastatin isoform h [Homo sapiens]                      32   3.7  
gi|109637761 calpastatin isoform g [Homo sapiens]                      32   3.7  
gi|109637759 calpastatin isoform f [Homo sapiens]                      32   3.7  
gi|109637757 calpastatin isoform e [Homo sapiens]                      32   3.7  
gi|27765085 calpastatin isoform b [Homo sapiens]                       32   3.7  
gi|109637753 calpastatin isoform a [Homo sapiens]                      32   3.7  
gi|122114654 methyltransferase 10 domain containing [Homo sapiens]     32   3.7  
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       32   3.7  

>gi|110618253 mitochondrial DNA-directed RNA polymerase precursor
            [Homo sapiens]
          Length = 1230

 Score = 2490 bits (6454), Expect = 0.0
 Identities = 1230/1230 (100%), Positives = 1230/1230 (100%)

Query: 1    MSALCWGRGAAGLKRALRPCGRPGLPGKEGTAGGVCGPRRSSSASPQEQDQDRRKDWGHV 60
            MSALCWGRGAAGLKRALRPCGRPGLPGKEGTAGGVCGPRRSSSASPQEQDQDRRKDWGHV
Sbjct: 1    MSALCWGRGAAGLKRALRPCGRPGLPGKEGTAGGVCGPRRSSSASPQEQDQDRRKDWGHV 60

Query: 61   ELLEVLQARVRQLQAESVSEVVVNRVDVARLPECGSGDGSLQPPRKVQMGAKDATPVPCG 120
            ELLEVLQARVRQLQAESVSEVVVNRVDVARLPECGSGDGSLQPPRKVQMGAKDATPVPCG
Sbjct: 61   ELLEVLQARVRQLQAESVSEVVVNRVDVARLPECGSGDGSLQPPRKVQMGAKDATPVPCG 120

Query: 121  RWAKILEKDKRTQQMRMQRLKAKLQMPFQSGEFKALTRRLQVEPRLLSKQMAGCLEDCTR 180
            RWAKILEKDKRTQQMRMQRLKAKLQMPFQSGEFKALTRRLQVEPRLLSKQMAGCLEDCTR
Sbjct: 121  RWAKILEKDKRTQQMRMQRLKAKLQMPFQSGEFKALTRRLQVEPRLLSKQMAGCLEDCTR 180

Query: 181  QAPESPWEEQLARLLQEAPGKLSLDVEQAPSGQHSQAQLSGQQQRLLAFFKCCLLTDQLP 240
            QAPESPWEEQLARLLQEAPGKLSLDVEQAPSGQHSQAQLSGQQQRLLAFFKCCLLTDQLP
Sbjct: 181  QAPESPWEEQLARLLQEAPGKLSLDVEQAPSGQHSQAQLSGQQQRLLAFFKCCLLTDQLP 240

Query: 241  LAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYA 300
            LAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYA
Sbjct: 241  LAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYA 300

Query: 301  AALQCMGRQDQDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSL 360
            AALQCMGRQDQDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSL
Sbjct: 301  AALQCMGRQDQDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSL 360

Query: 361  PPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKP 420
            PPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKP
Sbjct: 361  PPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKP 420

Query: 421  TLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYPFLCLLDEREVV 480
            TLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYPFLCLLDEREVV
Sbjct: 421  TLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYPFLCLLDEREVV 480

Query: 481  RMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASD 540
            RMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASD
Sbjct: 481  RMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASD 540

Query: 541  AEVPEPCLPRQYWEELGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDKPHRSS 600
            AEVPEPCLPRQYWEELGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDKPHRSS
Sbjct: 541  AEVPEPCLPRQYWEELGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDKPHRSS 600

Query: 601  RLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHS 660
            RLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHS
Sbjct: 601  RLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHS 660

Query: 661  GAFLLSPTKLMRTVEGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQL 720
            GAFLLSPTKLMRTVEGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQL
Sbjct: 661  GAFLLSPTKLMRTVEGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQL 720

Query: 721  FQAKGCPQLGVPAPPSEAPQPPEAHLPHSAAPARKAELRRELAHCQKVAREMHSLRAEAL 780
            FQAKGCPQLGVPAPPSEAPQPPEAHLPHSAAPARKAELRRELAHCQKVAREMHSLRAEAL
Sbjct: 721  FQAKGCPQLGVPAPPSEAPQPPEAHLPHSAAPARKAELRRELAHCQKVAREMHSLRAEAL 780

Query: 781  YRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDW 840
            YRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDW
Sbjct: 781  YRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDW 840

Query: 841  LKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCME 900
            LKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCME
Sbjct: 841  LKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCME 900

Query: 901  VANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVA 960
            VANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVA
Sbjct: 901  VANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVA 960

Query: 961  AQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDF 1020
            AQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDF
Sbjct: 961  AQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDF 1020

Query: 1021 PQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQ 1080
            PQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQ
Sbjct: 1021 PQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQ 1080

Query: 1081 PYRLDSKVKQIGGGIQSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCY 1140
            PYRLDSKVKQIGGGIQSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCY
Sbjct: 1081 PYRLDSKVKQIGGGIQSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCY 1140

Query: 1141 RKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQKILE 1200
            RKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQKILE
Sbjct: 1141 RKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQKILE 1200

Query: 1201 ASQLKETLQAVPKPGAFDLEQVKRSTYFFS 1230
            ASQLKETLQAVPKPGAFDLEQVKRSTYFFS
Sbjct: 1201 ASQLKETLQAVPKPGAFDLEQVKRSTYFFS 1230


>gi|224458301 family with sequence similarity 186, member A [Homo
            sapiens]
          Length = 2351

 Score = 38.9 bits (89), Expect = 0.030
 Identities = 68/307 (22%), Positives = 116/307 (37%), Gaps = 33/307 (10%)

Query: 48   EQDQDRRKDWGHVELLEVLQARVRQLQAESVSEVVVNRVDVARLPECG-----SGDGSLQ 102
            +Q+Q  +K W   E+ +  Q +    QAE   +      +   LP+        G   ++
Sbjct: 874  KQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSLQRLEEGTQKMK 933

Query: 103  PP-----------RKVQMGAKDATPVPCGRWAKILEKDKRTQQMRMQRLKAKLQMPFQSG 151
                         R++Q  AK   P       K  +K +R  +   +++K K QM  +  
Sbjct: 934  TQGLLLEKENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKET 993

Query: 152  EFKALTRRLQVEPRLLSKQMAGCLEDCTRQAPESPWEEQLARLLQEAPGKLSLDVEQAPS 211
            + K L + +   P  LS +    L+D  R      ++  L  L      K  + +   PS
Sbjct: 994  QPKELEKMVIQTPMTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPISITPPPS 1053

Query: 212  GQHS---QAQLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAVM 268
             Q+S      +SGQ        KC  LT Q   A  + +    Q+ + + +TL +  A  
Sbjct: 1054 LQYSLPGALPISGQ-----PLTKCIHLTPQ--QAQEVGITLTPQQAQAQGITLTLQQAQE 1106

Query: 269  LGWARQGAFKELVYVLFMVKDA-----GLTPDLLSYAAALQCMGRQDQDAGTIERCLEQM 323
            LG        + + +LF  + A      LTP   +    +    +QDQ  G I    +Q 
Sbjct: 1107 LGIPLTPQQAQALEILFTPQQAQALGIPLTPQ-QTQVQGITLTPQQDQAPG-ISLTTQQA 1164

Query: 324  SQEGLKL 330
             + G+ L
Sbjct: 1165 QKLGIPL 1171


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 38.5 bits (88), Expect = 0.040
 Identities = 55/248 (22%), Positives = 98/248 (39%), Gaps = 20/248 (8%)

Query: 20  CGRPGLPGKEGTAGGVCGPRRSSSASPQEQDQDRRK-----DWGHVELLEVLQARVRQLQ 74
           C   G PG +  +GG  G        PQE++   ++       G  E+ E  +   R+LQ
Sbjct: 31  CLEDGGPGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQ 90

Query: 75  AESVSEVVVNRVDVARLPECGSGDGSLQPPRKVQMGAKDATPVPCGRWAKILEKDKRTQQ 134
            + + +    + +  + P+    +   QP   +++      P   G+      + ++ Q 
Sbjct: 91  LQQLEQ----QPEPQQQPQ---HEQLQQPQPHLEL---QQQPQQDGQQQLSQLQQEKHQS 140

Query: 135 MRMQRLKAKLQMPFQSGEFKAL----TRRLQVEPRLLSKQMAGCLEDCTRQAPESPWEEQ 190
           +  Q LK +LQ+  Q  + +       +RLQ +   L  Q A   +   +Q  +   + Q
Sbjct: 141 VHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQ-EQQVLQQQEQLQQQVQ 199

Query: 191 LARLLQEAPGKLSLDVEQAPSGQHSQAQLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHH 250
             +LLQ+   +L          Q  Q Q   QQ++L    +  LL  Q  L   LL    
Sbjct: 200 EQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQ 259

Query: 251 GQRQKRKL 258
            Q Q++ L
Sbjct: 260 AQLQQQLL 267



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 44/193 (22%), Positives = 83/193 (43%), Gaps = 15/193 (7%)

Query: 38  PRRSSSASPQEQDQDRRKDWGHVELLEVLQA--RVRQLQAESVSEVVVNRVDVARLPECG 95
           P++       +  Q++ +   H EL   LQ   + +QLQ + V E    +    +L    
Sbjct: 122 PQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQ 181

Query: 96  SGDGS-LQPPRKVQMGAKDATPVPCGRWAKILEKDKRTQQMRMQRLKAKLQMPFQSGEFK 154
           + +   LQ   ++Q   ++          ++L++ +  +Q++ Q+L  + Q   Q  +F+
Sbjct: 182 AQEQQVLQQQEQLQQQVQEQ---------QLLQQQQ--EQLQQQQLLQQ-QEQLQQQQFQ 229

Query: 155 ALTRRLQVEPRLLSKQMAGCLEDCTRQAPESPWEEQLARLLQEAPGKLSLDVEQAPSGQH 214
               +LQ + +LL  Q  G L+    Q  ++  ++QL    Q    +  L  +Q    Q 
Sbjct: 230 QQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQ 289

Query: 215 SQAQLSGQQQRLL 227
            Q QL  QQQ  L
Sbjct: 290 QQQQLLQQQQEQL 302


>gi|46275820 tetratricopeptide repeat domain 9B [Homo sapiens]
          Length = 239

 Score = 38.1 bits (87), Expect = 0.052
 Identities = 46/145 (31%), Positives = 61/145 (42%), Gaps = 16/145 (11%)

Query: 711 GRVLDLVLQLFQAKGCPQLGVPAPPSEAPQPPEAHLPHSAAPARKAELRRELAHCQKVAR 770
           G+    +LQL  A+G    G+PAP   AP P       S  PAR +E +R L    +V  
Sbjct: 86  GKYHRALLQLKAAQGARPSGLPAP---APGPTS-----SPGPARLSEEQRRLVESTEV-- 135

Query: 771 EMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGR---TYPCPPHFNHLGSDVARALLEF 827
           E +      L +  L  + R R + L      +G    TY     F HLG D ARAL   
Sbjct: 136 ECYDSLTACLLQSELVNYERVREYCLKVLEKQQGNFKATYRAGIAFYHLG-DYARALRYL 194

Query: 828 AQGRPLGPHGLDWLKIHLVNLTGLK 852
            + R   P   D   +  + LT LK
Sbjct: 195 QEARSREP--TDTNVLRYIQLTQLK 217


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 35.4 bits (80), Expect = 0.34
 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 5/52 (9%)

Query: 9    GAAGLKRALRPCGRPGLPGKEGTAG--GVCGPRRSSSASPQEQDQDRRKDWG 58
            G  G K    P G PGL GKEG  G  G+ GP   S     + D+  R DWG
Sbjct: 1550 GDIGFKGIQGPRGPPGLMGKEGIVGPLGILGP---SGLPGPKGDKGSRGDWG 1598



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 14/26 (53%), Positives = 18/26 (69%)

Query: 8    RGAAGLKRALRPCGRPGLPGKEGTAG 33
            +G+ GLK    P GRPG PG++G AG
Sbjct: 1077 QGSRGLKGPPGPQGRPGRPGQQGVAG 1102


>gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Homo
           sapiens]
          Length = 1551

 Score = 35.4 bits (80), Expect = 0.34
 Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 40/172 (23%)

Query: 394 KTLQCLFEKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRA----- 448
           + LQCL ++++ +   SR    ++  PT   +E++  RK ++TLRD+  + L        
Sbjct: 417 RKLQCLEQEKVEL---SRKHQEALHAPT-DHRELEQLRKEVQTLRDRLPEMLRDKASLSQ 472

Query: 449 --------------LRETKNRLEREVYEGRFSLYPFLCLLDEREVVRM------LLQVLQ 488
                         LR+  +RL RE+ EGR  L        E+E+ R       LLQ LQ
Sbjct: 473 TDGPPAGSPGQDSDLRQELDRLHRELAEGRAGLQ-----AQEQELCRAQGQQEELLQRLQ 527

Query: 489 ALPAQGESFTTLARELSARTFSRHVVQRQ------RVSGQVQALQNHYRKYL 534
               +  +  +  R LS++       QR+       +S QV  LQ  + + L
Sbjct: 528 EAQEREAATASQTRALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRL 579


>gi|39930399 tumor protein p53 inducible nuclear protein 2 [Homo
           sapiens]
          Length = 220

 Score = 34.7 bits (78), Expect = 0.58
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 89  ARLPECGSGDGSLQPPRKVQMGAKDATPVPCGRWAKILEKDKRTQQMRMQRLKAKLQMPF 148
           A LP+    +G L P R+    A+ A P+P    A +LEK  + ++++  R +A+ +   
Sbjct: 128 AALPDGDLSEGELTPARREPRAARHAAPLPAR--AALLEKAGQVRRLQRARQRAE-RHAL 184

Query: 149 QSGEFKALTRRLQVEPRLLSKQMAGCLEDCTRQ 181
            +   +   R  +  PR    Q +   + C RQ
Sbjct: 185 SAKAVQRQNRARESRPRRSKNQSSFIYQPCQRQ 217


>gi|10092691 tight junction protein 3 [Homo sapiens]
          Length = 952

 Score = 34.3 bits (77), Expect = 0.75
 Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 12/87 (13%)

Query: 713 VLDLVLQLFQAKGCPQLGVPAPPSEAPQPPEAHLPHSAAPARKAELRRELAHCQKVAREM 772
           + DL  +L QA   P   +P PP  A + PEA    + +P     LRRE +   +   E 
Sbjct: 327 ISDLASELSQA---PPSHIPPPPRHAQRSPEA--SQTDSPVESPRLRRESSVDSRTISEP 381

Query: 773 HSLRAEA-------LYRLSLAQHLRDR 792
              R+E        +YR+  +Q + DR
Sbjct: 382 DEQRSELPRESSYDIYRVPSSQSMEDR 408


>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
          Length = 1060

 Score = 34.3 bits (77), Expect = 0.75
 Identities = 37/161 (22%), Positives = 73/161 (45%), Gaps = 6/161 (3%)

Query: 401 EKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRL--ER 458
           + Q+H+++  ++  ++     L +++   A  +++ LR+  ++ L  A+ ETK RL  E+
Sbjct: 31  DPQMHVKMCKKIAQLTKVIYALNTRQ-DEAEASMEALREAHQEELQNAVAETKARLLQEQ 89

Query: 459 EVYEGRFSLYPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQR 518
              E    L     L    E+ + L +  +AL A+  S     +E   R  + H  +   
Sbjct: 90  GCAEEEALLQRIQALESALELQKRLTE--EAL-AESASCRLETKERELRVEAEHAERVLT 146

Query: 519 VSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEELGAP 559
           +S ++  L+  Y + L  L S    P+  LP++  E    P
Sbjct: 147 LSREMLELKADYERRLQHLTSHEATPQGRLPQESPETKSEP 187


>gi|39725952 angiogenic factor VG5Q [Homo sapiens]
          Length = 714

 Score = 33.9 bits (76), Expect = 0.98
 Identities = 27/67 (40%), Positives = 34/67 (50%), Gaps = 6/67 (8%)

Query: 732 PAPPSEAPQPPEAHLPHSAAPARKAE-LRRELAHCQKVAREMHSL--RAEALYR--LSLA 786
           P+PP   P PP +  P  A   RK E L REL  C++  RE+  L    E LY+   S  
Sbjct: 6   PSPPRS-PPPPTSPEPELAQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNN 64

Query: 787 QHLRDRV 793
           Q LR +V
Sbjct: 65  QELRTQV 71


>gi|38158015 mastermind-like 3 [Homo sapiens]
          Length = 1133

 Score = 33.9 bits (76), Expect = 0.98
 Identities = 44/157 (28%), Positives = 63/157 (40%), Gaps = 23/157 (14%)

Query: 2   SALCWGRGAAGLKRALRPCGRPGLPGKEGTAGGVC----GPRRSSSASPQEQ---DQDRR 54
           S+L    G AG+     P   P  P     A G C    GP   S+A P+     ++ R+
Sbjct: 20  SSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQ 79

Query: 55  KDWG----HVEL-LEVLQARVRQLQAESVSEV-VVNRVDVARLPECGSGDGSLQPPRKVQ 108
           +  G    HV       QA+V QL+ E    V +  R    R  + G+G G  Q P K Q
Sbjct: 80  RIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQRAKKSGAGTGKQQHPSKPQ 139

Query: 109 MGAKDATPVPCGRWAKILEKDKRTQQMRMQRLKAKLQ 145
             A+ A+           E+   T  M  + +K KL+
Sbjct: 140 QDAEAAS----------AEQRNHTLIMLQETVKRKLE 166


>gi|151301215 widely-interspaced zinc finger motifs [Homo sapiens]
          Length = 794

 Score = 33.5 bits (75), Expect = 1.3
 Identities = 34/136 (25%), Positives = 51/136 (37%), Gaps = 30/136 (22%)

Query: 654 PWTSPHSGAFLLSPTKLMRTVEGATQHQ-----ELLETCPPTALHGALDALTQLGNCAWR 708
           PW +P      ++P  L    E     +     E  E     + H A   L Q+G   W 
Sbjct: 347 PWGAPRED---MTPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSH-ARSHLRQMGVTEWS 402

Query: 709 VNGRVLDLVLQLFQAKG--------------CPQLGVPAPPSEAPQPPEAHLPHSAAPAR 754
           VNG  +D + ++ + K                P L    PP+ AP P ++ LP S    R
Sbjct: 403 VNGSPIDTLREILKKKSKPCLIKKEPPAGDLAPALAEDGPPTVAPGPVQSPLPLSPLAGR 462

Query: 755 -------KAELRRELA 763
                   A++ REL+
Sbjct: 463 PGKPGAGPAQVPRELS 478


>gi|118498339 EMI domain containing 2 [Homo sapiens]
          Length = 439

 Score = 33.5 bits (75), Expect = 1.3
 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 17/118 (14%)

Query: 19  PCGRPGLPGKEGTAG--GVCGPRRSSSASPQEQDQDRRKDWGHV----ELLEVLQARVRQ 72
           P G PG PG +G AG  G  GP        +E ++    +   V    E L++L  RV  
Sbjct: 319 PPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQQLREALKILAERV-- 376

Query: 73  LQAESVSEVVVNRVDVARLPECGSG-DGSLQPPRKVQMGAKDATPVPCGRWAKILEKD 129
                + E ++   D    PE GSG D +L+   K++ G       P G  A +L  D
Sbjct: 377 ----LILEHMIGIHDPLASPEGGSGQDAALRANLKMKRGGAQ----PDGVLAALLGPD 426


>gi|116292168 KRAB A domain containing 1 [Homo sapiens]
          Length = 1030

 Score = 33.1 bits (74), Expect = 1.7
 Identities = 27/67 (40%), Positives = 35/67 (52%), Gaps = 10/67 (14%)

Query: 724 KGCPQLGVPAPPSEAPQPPEAHLPHSAAPARKAELRRELAHCQK-VAREMHSL---RAEA 779
           +G P+L   +PP E P PPEA     A P   A   +   HC K + +E+HSL    AE 
Sbjct: 760 QGPPELPSESPPPELP-PPEA-----APPVLPASSLQPPCHCGKPLQQELHSLGAALAEK 813

Query: 780 LYRLSLA 786
           L RL+ A
Sbjct: 814 LDRLATA 820


>gi|124378039 SEC16 homolog A [Homo sapiens]
          Length = 2357

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 18/59 (30%), Positives = 25/59 (42%)

Query: 757  ELRRELAHCQKVAREMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNH 815
            E+ R   H +  AR +HS  + A  R SL+ H      +  HN+       P PP   H
Sbjct: 1342 EVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIYRSHNVAAGSYEAPLPPGSFH 1400


>gi|4504465 homeobox B2 [Homo sapiens]
          Length = 356

 Score = 32.3 bits (72), Expect = 2.9
 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 21/96 (21%)

Query: 868 MDDILDSADQPLTGRKWWMGAEEPWQTLACCM--EVANAVRASDPAAYVSHLPVHQDGSC 925
           ++DI D A++P         +   W+  ACC   EV     ++DP      L V  +G+ 
Sbjct: 218 LEDICDPAEEPAASPGGPSASRAAWE--ACCHPPEVVPGALSADPRP----LAVRLEGA- 270

Query: 926 NGLQHYAALGRDSVGAA---SVNLEPSDVPQDVYSG 958
                    G  S G A   +  LEP  +P+DV+SG
Sbjct: 271 ---------GASSPGCALRGAGGLEPGPLPEDVFSG 297


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 22/137 (16%)

Query: 329 KLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVNTSKLLRDVYAKDGRVSYPK 388
           K Q L    +L E +     +  H+++   +LP  LPP + T                 K
Sbjct: 333 KPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRT-----------------K 375

Query: 389 LHLPLKTLQCL-FEKQLHMELASRVCVVSVEKPTLPSKEVKHA-RKTLKTLR--DQWEKA 444
             + LK L+ L F++QL  E+ + +   +  +  L SK  K + R+TL+  R  ++ EK 
Sbjct: 376 ATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQ 435

Query: 445 LCRALRETKNRLEREVY 461
             +  +E K R + + Y
Sbjct: 436 Q-KIEQERKRRQKHQEY 451


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 22/137 (16%)

Query: 329 KLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVNTSKLLRDVYAKDGRVSYPK 388
           K Q L    +L E +     +  H+++   +LP  LPP + T                 K
Sbjct: 333 KPQGLDPVEILQEREYRLQARIAHRIQELENLPGSLPPDLRT-----------------K 375

Query: 389 LHLPLKTLQCL-FEKQLHMELASRVCVVSVEKPTLPSKEVKHA-RKTLKTLR--DQWEKA 444
             + LK L+ L F++QL  E+ + +   +  +  L SK  K + R+TL+  R  ++ EK 
Sbjct: 376 ATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQ 435

Query: 445 LCRALRETKNRLEREVY 461
             +  +E K R + + Y
Sbjct: 436 Q-KIEQERKRRQKHQEY 451


>gi|109637771 calpastatin isoform l [Homo sapiens]
          Length = 654

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 42  SSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAE------SVSEVVVNRVDVARLPECG 95
           S+A PQE+ +   KD    + LE L A +   QAE      S+ EV   +    +L +CG
Sbjct: 216 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 275

Query: 96  SGDGSLQPPRKVQMGA-KDATPV 117
             D ++    +++    KD  P+
Sbjct: 276 EDDETIPSEYRLKPATDKDGKPL 298


>gi|109637769 calpastatin isoform k [Homo sapiens]
          Length = 673

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 42  SSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAE------SVSEVVVNRVDVARLPECG 95
           S+A PQE+ +   KD    + LE L A +   QAE      S+ EV   +    +L +CG
Sbjct: 235 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 294

Query: 96  SGDGSLQPPRKVQMGA-KDATPV 117
             D ++    +++    KD  P+
Sbjct: 295 EDDETIPSEYRLKPATDKDGKPL 317


>gi|109637767 calpastatin isoform j [Homo sapiens]
          Length = 667

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 42  SSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAE------SVSEVVVNRVDVARLPECG 95
           S+A PQE+ +   KD    + LE L A +   QAE      S+ EV   +    +L +CG
Sbjct: 229 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 288

Query: 96  SGDGSLQPPRKVQMGA-KDATPV 117
             D ++    +++    KD  P+
Sbjct: 289 EDDETIPSEYRLKPATDKDGKPL 311


>gi|109637765 calpastatin isoform i [Homo sapiens]
          Length = 708

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 42  SSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAE------SVSEVVVNRVDVARLPECG 95
           S+A PQE+ +   KD    + LE L A +   QAE      S+ EV   +    +L +CG
Sbjct: 270 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 329

Query: 96  SGDGSLQPPRKVQMGA-KDATPV 117
             D ++    +++    KD  P+
Sbjct: 330 EDDETIPSEYRLKPATDKDGKPL 352


>gi|109637763 calpastatin isoform h [Homo sapiens]
          Length = 769

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 42  SSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAE------SVSEVVVNRVDVARLPECG 95
           S+A PQE+ +   KD    + LE L A +   QAE      S+ EV   +    +L +CG
Sbjct: 331 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 390

Query: 96  SGDGSLQPPRKVQMGA-KDATPV 117
             D ++    +++    KD  P+
Sbjct: 391 EDDETIPSEYRLKPATDKDGKPL 413


>gi|109637761 calpastatin isoform g [Homo sapiens]
          Length = 772

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 42  SSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAE------SVSEVVVNRVDVARLPECG 95
           S+A PQE+ +   KD    + LE L A +   QAE      S+ EV   +    +L +CG
Sbjct: 334 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 393

Query: 96  SGDGSLQPPRKVQMGA-KDATPV 117
             D ++    +++    KD  P+
Sbjct: 394 EDDETIPSEYRLKPATDKDGKPL 416


>gi|109637759 calpastatin isoform f [Homo sapiens]
          Length = 750

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 42  SSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAE------SVSEVVVNRVDVARLPECG 95
           S+A PQE+ +   KD    + LE L A +   QAE      S+ EV   +    +L +CG
Sbjct: 312 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 371

Query: 96  SGDGSLQPPRKVQMGA-KDATPV 117
             D ++    +++    KD  P+
Sbjct: 372 EDDETIPSEYRLKPATDKDGKPL 394


>gi|109637757 calpastatin isoform e [Homo sapiens]
          Length = 756

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 42  SSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAE------SVSEVVVNRVDVARLPECG 95
           S+A PQE+ +   KD    + LE L A +   QAE      S+ EV   +    +L +CG
Sbjct: 318 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 377

Query: 96  SGDGSLQPPRKVQMGA-KDATPV 117
             D ++    +++    KD  P+
Sbjct: 378 EDDETIPSEYRLKPATDKDGKPL 400


>gi|27765085 calpastatin isoform b [Homo sapiens]
          Length = 686

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 42  SSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAE------SVSEVVVNRVDVARLPECG 95
           S+A PQE+ +   KD    + LE L A +   QAE      S+ EV   +    +L +CG
Sbjct: 248 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 307

Query: 96  SGDGSLQPPRKVQMGA-KDATPV 117
             D ++    +++    KD  P+
Sbjct: 308 EDDETIPSEYRLKPATDKDGKPL 330


>gi|109637753 calpastatin isoform a [Homo sapiens]
          Length = 791

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 42  SSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAE------SVSEVVVNRVDVARLPECG 95
           S+A PQE+ +   KD    + LE L A +   QAE      S+ EV   +    +L +CG
Sbjct: 353 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 412

Query: 96  SGDGSLQPPRKVQMGA-KDATPV 117
             D ++    +++    KD  P+
Sbjct: 413 EDDETIPSEYRLKPATDKDGKPL 435


>gi|122114654 methyltransferase 10 domain containing [Homo sapiens]
          Length = 562

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 8/67 (11%)

Query: 19  PCGRPGLPGKEGTAGGVCGPRRSSSASPQEQ-----DQDRRKDWGHVELLEVLQARVRQL 73
           PCG P L  +EG A  V GP  S  +  QE+     + +R ++ G VE+LE  Q      
Sbjct: 431 PCG-PAL--REGEAAAVEGPCPSQESLSQEENPEPTEDERSEEKGGVEVLESCQGSSNGA 487

Query: 74  QAESVSE 80
           Q +  SE
Sbjct: 488 QDQEASE 494


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 32.0 bits (71), Expect = 3.7
 Identities = 25/57 (43%), Positives = 29/57 (50%), Gaps = 5/57 (8%)

Query: 831 RPLGPHG--LD--WLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRK 883
           RPL  H   LD  W KIHL NL   +  E L+ R      V+D +LD   Q LTG K
Sbjct: 455 RPLNSHATLLDKYWTKIHLDNLDKRELNEVLQSRYPSLLAVVDHLLDIYIQ-LTGEK 510


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,522,217
Number of Sequences: 37866
Number of extensions: 2381119
Number of successful extensions: 12397
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 12018
Number of HSP's gapped (non-prelim): 421
length of query: 1230
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1116
effective length of database: 13,930,794
effective search space: 15546766104
effective search space used: 15546766104
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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