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Search of human proteins with 110611184
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110611184 chromodomain helicase DNA binding protein 2
isoform 2 [Homo sapiens]
(501 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 1014 0.0
gi|110611184 chromodomain helicase DNA binding protein 2 isoform... 1014 0.0
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 470 e-132
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 108 9e-24
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa... 99 1e-20
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 90 4e-18
gi|114326455 chromodomain helicase DNA binding protein 8 [Homo s... 88 2e-17
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 70 3e-12
gi|217330641 IWS1 homolog [Homo sapiens] 70 6e-12
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 68 2e-11
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 68 2e-11
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 67 5e-11
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 67 5e-11
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 64 4e-10
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 63 5e-10
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 62 9e-10
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 62 1e-09
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 61 2e-09
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 61 3e-09
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 61 3e-09
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 60 4e-09
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s... 60 4e-09
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa... 60 4e-09
gi|117676384 splicing factor, arginine/serine-rich 2, interactin... 59 8e-09
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 59 8e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 1e-08
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 59 1e-08
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 59 1e-08
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 59 1e-08
gi|87299628 biorientation of chromosomes in cell division 1-like... 58 2e-08
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 1014 bits (2623), Expect = 0.0
Identities = 501/501 (100%), Positives = 501/501 (100%)
Query: 1 MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60
MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS
Sbjct: 1 MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60
Query: 61 ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS
Sbjct: 61 ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
Query: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP
Sbjct: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
Query: 181 VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET 240
VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET
Sbjct: 181 VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET 240
Query: 241 DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK 300
DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK
Sbjct: 241 DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK 300
Query: 301 DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV 360
DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV
Sbjct: 301 DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV 360
Query: 361 EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL 420
EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL
Sbjct: 361 EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL 420
Query: 421 PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE 480
PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE
Sbjct: 421 PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE 480
Query: 481 NLELRDYQLEGLNWLAHSWCK 501
NLELRDYQLEGLNWLAHSWCK
Sbjct: 481 NLELRDYQLEGLNWLAHSWCK 501
Score = 39.3 bits (90), Expect = 0.008
Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 12/96 (12%)
Query: 145 LKKQEKWKQEPSED-----EQEQGTSAESEPEQKKVKARRPVPR--RTVPKPRVKKQPKT 197
++ +E+ ++ P +D +EQ E E QK+++ +PR + K +
Sbjct: 1029 MEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSD 1088
Query: 198 QRGKRKKQDSS-----DEDDDDDEAPKRQTRRRAAK 228
KR+ Q SS ED DDD+ PKR+ R R+ +
Sbjct: 1089 TESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVR 1124
Score = 36.2 bits (82), Expect = 0.071
Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 10/135 (7%)
Query: 83 KEKPASKKERIADVKKMWEEYPDVYGVRRSN-RSRQEPSRFNIKEEASSGSESGSPKRRG 141
K KP KKE V ++ EE+ G+ S+ R PS E G E K++
Sbjct: 1341 KRKPRVKKEN--KVPRLKEEH----GIELSSPRHSDNPSEEG--EVKDDGLEKSPMKKKQ 1392
Query: 142 QRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGK 201
+++ K+ K KQ S ++E G + + KK K + + + R + G
Sbjct: 1393 KKKENKENKEKQMSSRKDKE-GDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGS 1451
Query: 202 RKKQDSSDEDDDDDE 216
DEDDD D+
Sbjct: 1452 EPVPIGEDEDDDLDQ 1466
Score = 31.2 bits (69), Expect = 2.3
Identities = 27/133 (20%), Positives = 56/133 (42%), Gaps = 5/133 (3%)
Query: 171 EQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDS-SDEDDDDDEAPKRQTRRRAAKN 229
E+ K+K R+P ++ PR+K++ + + D+ S+E + D+ ++ ++ K
Sbjct: 1335 EEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKK 1394
Query: 230 VSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEAN 289
KE+ + + S EG E++ + + EK + S I A
Sbjct: 1395 KENKENKEKQMSS----RKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAG 1450
Query: 290 GDPSGDFDTEKDE 302
+P + E D+
Sbjct: 1451 SEPVPIGEDEDDD 1463
Score = 30.4 bits (67), Expect = 3.9
Identities = 34/156 (21%), Positives = 56/156 (35%), Gaps = 16/156 (10%)
Query: 9 QEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESES 68
+E L S S + SEE D G + + + + E+ E Q S
Sbjct: 1357 EEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQ-------KKKENKENKEKQMSSRK 1409
Query: 69 ESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEA 128
+ G K + + KEKP S + + K + + + EP E+
Sbjct: 1410 DKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHI-------TAGSEPVPIGEDEDD 1462
Query: 129 SSGSESGSPKRRGQRQLKKQEKWKQEPSE--DEQEQ 162
E+ S + R +KK K +P + + QEQ
Sbjct: 1463 DLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQ 1498
>gi|110611184 chromodomain helicase DNA binding protein 2 isoform 2
[Homo sapiens]
Length = 501
Score = 1014 bits (2623), Expect = 0.0
Identities = 501/501 (100%), Positives = 501/501 (100%)
Query: 1 MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60
MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS
Sbjct: 1 MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60
Query: 61 ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS
Sbjct: 61 ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
Query: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP
Sbjct: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
Query: 181 VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET 240
VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET
Sbjct: 181 VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET 240
Query: 241 DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK 300
DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK
Sbjct: 241 DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK 300
Query: 301 DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV 360
DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV
Sbjct: 301 DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV 360
Query: 361 EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL 420
EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL
Sbjct: 361 EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL 420
Query: 421 PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE 480
PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE
Sbjct: 421 PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE 480
Query: 481 NLELRDYQLEGLNWLAHSWCK 501
NLELRDYQLEGLNWLAHSWCK
Sbjct: 481 NLELRDYQLEGLNWLAHSWCK 501
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 470 bits (1210), Expect = e-132
Identities = 247/512 (48%), Positives = 334/512 (65%), Gaps = 45/512 (8%)
Query: 20 SSHSASEEA-SGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQS-ESESES---AGSK 74
+ HS E + S SQS+ + GS GSG GS S SSS+ S SQS S+S+S +GS+
Sbjct: 2 NGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQ 61
Query: 75 SQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRS-----------NRSRQEPSRFN 123
S+ ++E K D + W+ P + V+RS + Q S
Sbjct: 62 SESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSG 121
Query: 124 IKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPV-- 181
+E++SS +S +R+ K E W+ S + G+ +ESE E++K
Sbjct: 122 SEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESD 181
Query: 182 --PRRTVPKPRVKKQPKTQRGKR-----KKQ-DSSDEDDDDDEAP--KRQTRRRAAKNVS 231
P+ V + + + K++ GK+ K+Q DSS+EDDD+++ KR +RR+A NVS
Sbjct: 182 YEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVS 241
Query: 232 YKEDDDFETDSDDLIEMTGEGVDE-QQDNSETIEKVLDSRLGKKGATGASTTVYAIEANG 290
YKED++ +TDSDDL+E+ GE V + +++ ETIE+ +D R+G+KGATGA+TT+YA+EA+G
Sbjct: 242 YKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADG 301
Query: 291 DPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQ 350
DP+ F+ K+ GEIQYLIKWKGWS+IH+TWE+EE+L+QQ V+G+KKL+N+KKK+ E K+
Sbjct: 302 DPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKR 361
Query: 351 WLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNE 410
WL SPEDVEY+NCQQEL +L+KQYQIVER+I AHS + + +
Sbjct: 362 WLKNASPEDVEYYNCQQELTDDLHKQYQIVERII---------------AHSNQKSAAGY 406
Query: 411 PEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVAL 470
P+Y CKW GLPYSECSWED ALI KKFQ CID + SRN SKT P ++CK LKQRPRFVAL
Sbjct: 407 PDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVAL 466
Query: 471 KKQPAYLGG-ENLELRDYQLEGLNWLAHSWCK 501
KKQP+Y+GG E LELRDYQL GLNWLAHSWCK
Sbjct: 467 KKQPSYIGGHEGLELRDYQLNGLNWLAHSWCK 498
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 108 bits (271), Expect = 9e-24
Identities = 111/463 (23%), Positives = 189/463 (40%), Gaps = 98/463 (21%)
Query: 74 KSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRR--SNRSRQEPSRFNIKEEASSG 131
KS LP +++P KK++ + + E+ +G QE +R ++
Sbjct: 582 KSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNRNSLDGSQEEK 641
Query: 132 SESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRV 191
+ K + + K+ K K+EP E + + EP++KK K P P+ + K
Sbjct: 642 KKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSS--KKSS 699
Query: 192 KKQP---------KTQRGKRKKQDSSDED--------DDDDEAPKRQTRR--RAAKNVSY 232
K+P K +GK + ++SD D ++DE P Q RR R K Y
Sbjct: 700 NKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPEEDEDPGVQKRRSSRQVKRKRY 759
Query: 233 KEDDDFETDSDDLIEMTGEGVD--------EQQDNSE----TIEKVLDSRLGKKGATGAS 280
ED +F+ ++ + G D EQQ++ + +EK++ SR KK
Sbjct: 760 TEDLEFKISDEEADDADAAGRDSPSNTSQSEQQESVDAEGPVVEKIMSSRSVKK------ 813
Query: 281 TTVYAIEANGDPSGDFDTEKDEGE----IQYLIKWKGWSYIHSTWESEESLQQQKVKGLK 336
+K+ GE ++ +K+K +SY+H W S E L++ K + +
Sbjct: 814 ------------------QKESGEEVEIEEFYVKYKNFSYLHCQWASIEDLEKDK-RIQQ 854
Query: 337 KLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQT 396
K++ FK K+ + K +L ++ E N Y V+R++ S G+
Sbjct: 855 KIKRFKAKQGQNK-FLSEIEDE-------------LFNPDYVEVDRIMDFARSTDDRGEP 900
Query: 397 DFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTR 456
YL KW LPY + +WE I + + SR
Sbjct: 901 -------------VTHYLVKWCSLPYEDSTWERRQDIDQAKIEEFEKLMSRE-------P 940
Query: 457 ECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSW 499
E + +++ P K + + N +LR+YQLEG+NWL +W
Sbjct: 941 ETERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNW 983
Score = 33.5 bits (75), Expect = 0.46
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 12/77 (15%)
Query: 7 KSQEEDSSLHSNASSHSASEEAS-----------GSDSGSQSESEQGSDPGSGHGSESNS 55
K +EE++ S EAS G+D+GS+S SE+GS+ E +
Sbjct: 2190 KEEEEETDGSGKESKQECEAEASSVKNELKGVEVGADTGSKSISEKGSEEDEEEKLEDDD 2249
Query: 56 SSESSESQSESESESAG 72
SE S SQ E+ + S G
Sbjct: 2250 KSEES-SQPEAGAVSRG 2265
>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
sapiens]
Length = 2715
Score = 98.6 bits (244), Expect = 1e-20
Identities = 116/514 (22%), Positives = 203/514 (39%), Gaps = 123/514 (23%)
Query: 8 SQEEDSSLHSNA-SSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSES 66
++EE ++L +SH+ E++ G +G + + ++ +PG G+ S + + +
Sbjct: 64 AEEEAATLFPRKMTSHNGMEDSGGGGTGVKKKRKK-KEPGDQEGAAKGSKDREPKPKRKR 122
Query: 67 ESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKE 126
E + +P P ++P KE +E G +++ + R+ KE
Sbjct: 123 EPK------EPKEPRKAKEPKKAKEH--------KEPKQKDGAKKARKPREASGTKEAKE 168
Query: 127 EASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTV 186
+ S + K R + +EQG + P +KK K +R T
Sbjct: 169 KRSCTDSAARTKSR----------------KASKEQGPT----PVEKKKKGKR--KSETT 206
Query: 187 PKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDD-- 244
+ Q T R ++S++ D RQ +RR Y ED DF+ DD
Sbjct: 207 VESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRR-----KYNEDLDFKVVDDDGE 261
Query: 245 LIEMTGEG--------------VDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANG 290
I + G G + +D++ IEK+L AS TV +
Sbjct: 262 TIAVLGAGRTSALSASTLAWQAEEPPEDDANIIEKIL-----------ASKTVQEVHPGE 310
Query: 291 DPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQ 350
P FD E + +K++ +SY+H W + E L++ + +K++ F+ K+ ++K
Sbjct: 311 PP---FDLE------LFYVKYRNFSYLHCKWATMEELEKDP-RIAQKIKRFRNKQAQMKH 360
Query: 351 WLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNE 410
+ D + F N Y V+R++ V AH++ E
Sbjct: 361 IF---TEPDEDLF----------NPDYVEVDRILEV-------------AHTKDAETGEE 394
Query: 411 -PEYLCKWMGLPYSECSWEDEALIG----KKFQNCIDSFHSRNNSKTIPTRECKALKQRP 465
YL KW LPY E +WE E + K+F++ + +P +
Sbjct: 395 VTHYLVKWCSLPYEESTWELEEDVDPAKVKEFESL----------QVLPEIKHVERPASD 444
Query: 466 RFVALKKQPAYLGGENLELRDYQLEGLNWLAHSW 499
+ L+K Y +LR+YQLEG+NWL +W
Sbjct: 445 SWQKLEKSREYKNSN--QLREYQLEGMNWLLFNW 476
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 90.1 bits (222), Expect = 4e-18
Identities = 115/522 (22%), Positives = 208/522 (39%), Gaps = 113/522 (21%)
Query: 12 DSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESA 71
D L +SH + + + + QS++ S H + + + Q S +S
Sbjct: 433 DHDLDRQFTSHLVTRPSDMAQTQLQSQARSWHSSFSNHQHLHDRNHLCLQRQPPSSKKSD 492
Query: 72 GSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSG 131
GS + L + + S+K++ V+ + S+QE + I E +
Sbjct: 493 GSGTYTKLQNTQVRVMSEKKQRKKVE---------------SESKQEKANRIISEAIAKA 537
Query: 132 SESGSPKRRGQRQLKKQEKWKQEPSED----EQEQGTSAESEPEQKKVKARRPVPRRTVP 187
E RG+R + + + P+ E+++G +S+P+ K K + +
Sbjct: 538 KE------RGERNIPRVMSPENFPTASVEGKEEKKGRRMKSKPKDKDSKKTKTCSKLK-E 590
Query: 188 KPRVKKQPKTQRGKRK-KQDSSDEDDDDDEAPKR-------QTRR--RAAKNVSYKEDDD 237
K ++ K T K+K K +SSDE D ++ P+ Q RR R K Y ED +
Sbjct: 591 KTKIGKLIITLGKKQKRKNESSDEISDAEQMPQHTLKDQDSQKRRSNRQIKRKKYAEDIE 650
Query: 238 FETDSDDL----------IEMTGEGV------DEQQDNSETIEKVLDSRLGKKGATGAST 281
+ +++ + GE + ++++ ++K+L SR KK +
Sbjct: 651 GKQSEEEVKGSMKIKKNSAPLPGEQPLQLFVENPSEEDAAIVDKILSSRTVKKEIS---- 706
Query: 282 TVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENF 341
P DTE ++ +K+K +SY+H W +EE L + K + +K++ F
Sbjct: 707 ----------PGVMIDTE------EFFVKYKNYSYLHCEWATEEQLLKDK-RIQQKIKRF 749
Query: 342 KKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAH 401
K ++ + + + E N Y V+RV+ V +
Sbjct: 750 KLRQAQRAHFFADMEEEP-------------FNPDYVEVDRVLEVSFCEDK--------- 787
Query: 402 SRKPAPSNEPE--YLCKWMGLPYSECSWE--DEALIGKKFQNCIDSFHSRNNSKTIPTRE 457
+ EP YL KW LPY + +WE ++ + K I+ F S+ +
Sbjct: 788 -----DTGEPVIYYLVKWCSLPYEDSTWELKEDVDLAK-----IEEFEQLQASRP----D 833
Query: 458 CKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSW 499
+ L + P + K + +LR+YQLEGLNWL +W
Sbjct: 834 TRRLDRPPSNIWKKIDQSRDYKNGNQLREYQLEGLNWLLFNW 875
Score = 49.7 bits (117), Expect = 6e-06
Identities = 35/100 (35%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
Query: 8 SQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESE 67
S E SS S +SS S+S S S SGS S S S S S SSS SS S S E
Sbjct: 2136 SDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEE 2195
Query: 68 SESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVY 107
S+S ++Q A +E +A + +E D +
Sbjct: 2196 SDSDEEEAQK-RESTTHMKAYDEESVASLSTTQDETQDSF 2234
Score = 37.7 bits (86), Expect = 0.025
Identities = 31/107 (28%), Positives = 43/107 (40%), Gaps = 19/107 (17%)
Query: 15 LHSNASSHSASEEASGSDSGSQSESE-------------------QGSDPGSGHGSESNS 55
L N +S GS+S S S+S+ S GS S S+
Sbjct: 2112 LTPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSC 2171
Query: 56 SSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEE 102
SS SS S S + S S+ S S ++ E+ A K+E +K EE
Sbjct: 2172 SSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEE 2218
Score = 30.4 bits (67), Expect = 3.9
Identities = 27/94 (28%), Positives = 34/94 (36%), Gaps = 23/94 (24%)
Query: 147 KQEKWKQEPSEDEQEQGTSAE------SEPEQKKVKA-----------------RRPVPR 183
K E K+EP E+E +S E SEP K RR V
Sbjct: 2048 KSENLKEEPQSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAA 2107
Query: 184 RTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEA 217
RT P K + KR + SSD D D + +
Sbjct: 2108 RTEPLTPNPASKKPRVHKRGSESSSDSDSDSERS 2141
>gi|114326455 chromodomain helicase DNA binding protein 8 [Homo
sapiens]
Length = 2302
Score = 87.8 bits (216), Expect = 2e-17
Identities = 116/495 (23%), Positives = 199/495 (40%), Gaps = 91/495 (18%)
Query: 20 SSHSASEEASGSDSGSQSESEQGSDPGSG--HGSESNSSSESSESQSESESESAGSKSQP 77
SS AS S S SE S P S H E+ + + + E A
Sbjct: 129 SSQGASSGLSVVKVLSASEVAALSSPASSAPHSGGKTGMEENRRLEHQKKQEKANRIVAE 188
Query: 78 VLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSE-SGS 136
+ A+ + R+ + ++ P+ G ++ R++ + +KEE S+ SG+
Sbjct: 189 AIARARARGEQNIPRVLNEDELPSVRPEEEGEKKR---RKKSAGERLKEEKPKKSKTSGA 245
Query: 137 PKRRGQRQL--------KKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPK 188
K +G+ +L KK+++ + D + + E E+ ++ RR
Sbjct: 246 SKTKGKSKLNTITPVVGKKRKRNTSSDNSDVEVMPAQSPREDEESSIQKRRS-------N 298
Query: 189 PRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEM 248
+VK++ T+ K D +E++ D P K + E D + L M
Sbjct: 299 RQVKRKKYTEDLDIKITDDEEEEEVDVTGP--------IKPEPILPEPVQEPDGETLPSM 350
Query: 249 TGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYL 308
+ ++++ ++KVL R+ KK PSG + TE +E +
Sbjct: 351 QFFVENPSEEDAAIVDKVLSMRIVKKEL---------------PSGQY-TEAEE----FF 390
Query: 309 IKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQE 368
+K+K +SY+H W + L++ K + +KL+ FK K +++ + ED E FN
Sbjct: 391 VKYKNYSYLHCEWATISQLEKDK-RIHQKLKRFKTKMAQMRHFFH----EDEEPFN---- 441
Query: 369 LASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPE--YLCKWMGLPYSECS 426
Y V+R++ S + EP YL KW LPY + +
Sbjct: 442 ------PDYVEVDRILDESHSIDK--------------DNGEPVIYYLVKWCSLPYEDST 481
Query: 427 WEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALK-QRPRFVALKKQPAYLGGENL-EL 484
WE + +D R K I +R + + RP+ A KK +N +L
Sbjct: 482 WE--------LKEDVDEGKIRE-FKRIQSRHPELKRVNRPQASAWKKLELSHEYKNRNQL 532
Query: 485 RDYQLEGLNWLAHSW 499
R+YQLEG+NWL +W
Sbjct: 533 REYQLEGVNWLLFNW 547
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 70.5 bits (171), Expect = 3e-12
Identities = 66/295 (22%), Positives = 113/295 (38%), Gaps = 38/295 (12%)
Query: 5 KDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHG--SESNSSSESSES 62
K KS + + + EA + E+ P E S E ++S
Sbjct: 665 KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS 724
Query: 63 QSESESESAGSKSQPVLPEAKEKPASK---KERIADVKKMWEEYPDVYGVRRSNRSRQEP 119
+ E+++ PV EAK +K K + DVK + P R E
Sbjct: 725 PVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEK 784
Query: 120 SRFNIKEEASSGSESGSPKRRG----QRQLKKQEKWKQEPSEDEQEQGTSAESEP----- 170
++ +KEE S ++ SP + ++++ K+E+ K E+E+ Q + P
Sbjct: 785 AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEE 844
Query: 171 ---------EQKKVKARRPVPRRTVPKPRV--KKQPKTQRGKRKKQDSSDEDDDD----- 214
E+KK + P++ PKP+V KK+P ++ K K ++ E+ +D
Sbjct: 845 EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVP 904
Query: 215 ---DEAP-----KRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSE 261
EAP K + + V+ KE DD + E E++D E
Sbjct: 905 TPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKE 959
Score = 62.8 bits (151), Expect = 7e-10
Identities = 59/273 (21%), Positives = 106/273 (38%), Gaps = 33/273 (12%)
Query: 5 KDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSS----SESS 60
K KS ++ + + EEA + E+ P E + S +
Sbjct: 707 KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA 766
Query: 61 ESQSESESESAGSK-----SQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRS 115
++ ++ E+ S K PV E K +K D K +E P V+ +
Sbjct: 767 KTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKE 826
Query: 116 RQEPSRFNIKEEASSGSES---GSPKRRGQRQLKKQEKWKQE-PSEDEQEQGTSAESEPE 171
++P +KE E +PK ++ KK+E K+E P +E+ A +P+
Sbjct: 827 EEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK 886
Query: 172 QKKVKARR---------PVPRRTVP-----KPRVKKQPKTQRGKRKKQDSSDED-----D 212
+ KV+A++ P P + P K K + KT+ K++ D+ ++ +
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAE 946
Query: 213 DDDEAP-KRQTRRRAAKNVSYKEDDDFETDSDD 244
+ AP K+ T+ AK K + + DD
Sbjct: 947 KKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979
Score = 56.6 bits (135), Expect = 5e-08
Identities = 48/235 (20%), Positives = 96/235 (40%), Gaps = 8/235 (3%)
Query: 3 RNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSE-SEQGSDPGSGHGSESNSSSESSE 61
+ ++ +EE++ + +EEA+ + ++S E+ P E + +E
Sbjct: 484 KEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAE 543
Query: 62 SQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSR 121
+S +++S + PEAK + + A+VK + +S + P +
Sbjct: 544 VKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEK 603
Query: 122 FN--IKEEASSGSESGSP---KRRGQRQLKKQEKWKQEPSEDEQ--EQGTSAESEPEQKK 174
+KEEA S +E+ SP + + ++K EK K E+ + E+ S E E +
Sbjct: 604 AKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP 663
Query: 175 VKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKN 229
KA+ PV + K K + +K S +++ + + AK+
Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718
Score = 56.2 bits (134), Expect = 7e-08
Identities = 58/264 (21%), Positives = 108/264 (40%), Gaps = 27/264 (10%)
Query: 26 EEASGSDSGSQSESEQGSDPGSGHG--SESNSSSESSESQSESESESAGSKSQPVLPEAK 83
EEA + E E+ P S E ++S ++E++S PV EAK
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703
Query: 84 EKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQR 143
P K + + K E+ + E ++ +KEEA S ++ SP++
Sbjct: 704 S-PEKAKSPVKEEAKSPEKAKSPV---KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL 759
Query: 144 QLKKQE------KWKQEPSEDEQEQGTSAESEPEQKKVKARRPV------PRRTVPKPR- 190
+K E + + P++ E+ S E + KA+ P+ P + +PK
Sbjct: 760 DVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEE 819
Query: 191 ----VKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKED---DDFETDSD 243
VK++ K Q K K+ E++ PK + ++ + K + K++ E +
Sbjct: 820 VKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKE 879
Query: 244 DLIEMTGEG-VDEQQDNSETIEKV 266
+E E V+ +++ +E +KV
Sbjct: 880 PAVEKPKESKVEAKKEEAEDKKKV 903
Score = 53.5 bits (127), Expect = 4e-07
Identities = 50/232 (21%), Positives = 102/232 (43%), Gaps = 23/232 (9%)
Query: 6 DKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSE 65
+KS++E + +EE + + +++ E+G + G E+ E ++S
Sbjct: 448 EKSEKETVIVEEQTEETQVTEEVTEEEE-KEAKEEEGKEEEGGEEEEAEGGEEETKSPPA 506
Query: 66 SESESAGSKSQ-PVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNI 124
E+ S +++ PV EAK +K + K E +S + P+
Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV--------KSPEKAKSPA---- 554
Query: 125 KEEASSGSESGSPKR---RGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQK---KVKAR 178
KEEA S E+ SP++ + ++K EK K P+++E + A+S + K K +A+
Sbjct: 555 KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAK-SPAKEEAKSPAEAKSPEKAKSPVKEEAK 613
Query: 179 RPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEA--PKRQTRRRAAK 228
P ++ K K + + ++ K + +E ++A P+++ + K
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665
Score = 52.8 bits (125), Expect = 7e-07
Identities = 47/221 (21%), Positives = 85/221 (38%), Gaps = 11/221 (4%)
Query: 24 ASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAK 83
A EEA E E+ P E S E++S +E++S PV EAK
Sbjct: 554 AKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613
Query: 84 EKPASKKERIADVKKMWEEYPDVYGVR---RSNRSRQEPSRFNIKEEASSGSESGSPKR- 139
PA K + + K E + + E ++ KEEA S ++ SP +
Sbjct: 614 -SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA 672
Query: 140 ------RGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKK 193
+ + +K + K ++ +E+ S E K +A+ P ++ K K
Sbjct: 673 EAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT 732
Query: 194 QPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKE 234
K + +++ S ++ ++A + AK + +E
Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 773
Score = 48.5 bits (114), Expect = 1e-05
Identities = 50/238 (21%), Positives = 94/238 (39%), Gaps = 16/238 (6%)
Query: 7 KSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSES 66
KS E+ S + A ++ + + + E S E ++S +
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
Query: 67 ESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKE 126
E++S PV EAK +K A+ K + V +S + P +KE
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP----VKE 714
Query: 127 EASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP---VPR 183
EA S ++ SP + + K EK K P ++E + A+S + K + + P P
Sbjct: 715 EAKSPEKAKSPVK---EEAKTPEKAK-SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPA 770
Query: 184 RTVPKPRVKKQPKTQRGKRKKQDSSDED-----DDDDEAPKRQTRRRAAKNVSYKEDD 236
+ + K P+ + K++ S E +D +AP+++ ++ KE++
Sbjct: 771 KEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEE 828
Score = 41.6 bits (96), Expect = 0.002
Identities = 45/233 (19%), Positives = 90/233 (38%), Gaps = 44/233 (18%)
Query: 36 QSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIAD 95
Q+E Q ++ + + E E + E E+ G + + P A+E + +KE
Sbjct: 460 QTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKE---- 515
Query: 96 VKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKR---RGQRQLKKQEKWK 152
++ +KEEA S +E+ SP++ + ++K EK K
Sbjct: 516 ------------------------AKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK 551
Query: 153 QEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDD 212
P+++E + A+S PE+++ K+ P K P+ + K++ S +
Sbjct: 552 S-PAKEEAKSPPEAKS-PEKEEAKS-----------PAEVKSPEKAKSPAKEEAKSPAEA 598
Query: 213 DDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEK 265
E K + A K E S ++ + ++ +++ EK
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK 651
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 69.7 bits (169), Expect = 6e-12
Identities = 83/361 (22%), Positives = 144/361 (39%), Gaps = 55/361 (15%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEAS---GSDSGSQSESEQGSD---------PGSGHGS 51
N + S E LH S S SEE + SDS ++ ++ GSD PGS +
Sbjct: 76 NLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSEN 135
Query: 52 ESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRR 111
E + +S+S++E + S S+ + E ++ PAS E +K + R
Sbjct: 136 EELLNGHASDSENEDVGKHPASDSE--IEELQKSPASDSETEDALKPQISDSESEEPPRH 193
Query: 112 --SNRSRQEPSRFNIKEEAS--------SGSESGSPKRRGQRQLKKQEKWKQEPSEDEQE 161
S+ +EP + + + S S SES P R + +E K S+ E E
Sbjct: 194 QASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESE 253
Query: 162 ---QGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDED------- 211
+ +++SE E+ +PKPR+ + + DS +E+
Sbjct: 254 DPPRHQASDSENEE-------------LPKPRISDSESEDPPRNQASDSENEELPKPRVS 300
Query: 212 DDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRL 271
D + E P++ + + + E+D D E GE + Q D+ + DS +
Sbjct: 301 DSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHS-----DSHM 355
Query: 272 GKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQK 331
+K + + E + D D ++ EGE + + K K S E + S ++ +
Sbjct: 356 DRKKFHSSDSEE---EEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSR 412
Query: 332 V 332
V
Sbjct: 413 V 413
Score = 47.4 bits (111), Expect = 3e-05
Identities = 78/355 (21%), Positives = 134/355 (37%), Gaps = 49/355 (13%)
Query: 25 SEEASGSDSG-----SQSESEQGSD--PGSGHGSESNSSSESSESQSESESESAGSK--S 75
+E+ SGSD+G S++E+ D P H ++S + + + S+SESE + S
Sbjct: 34 NEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDS 93
Query: 76 QPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSG---- 131
E E PAS E DV + + S +R+ P + EE +G
Sbjct: 94 DSESEERAEPPASDSEN-EDVNQHGSD-------SESEETRKLPGSDSENEELLNGHASD 145
Query: 132 SESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTS---AESEPEQKKVKARRPVPRRTVPK 188
SE+ + + +E K S+ E E ++SE E+ PK
Sbjct: 146 SENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPK 205
Query: 189 PRVKKQPKTQRGKRKKQDSSDE--------DDDDDEAPKRQTRRRAAKNVSYKEDDDFET 240
PR+ + K + DS E D +++E PK + +++ + D E
Sbjct: 206 PRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSEN 265
Query: 241 D-------SDDLIEMTGEGVDEQQDNSETIE-KVLDSRL--GKKGATGASTTVYAIEANG 290
+ SD E +N E + +V DS +KG S T A
Sbjct: 266 EELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQ 325
Query: 291 DPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKE 345
P D D++++ K + + ++ S+ + ++K E KK+
Sbjct: 326 KPESDDDSDREN-------KGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQ 373
Score = 47.0 bits (110), Expect = 4e-05
Identities = 66/314 (21%), Positives = 121/314 (38%), Gaps = 31/314 (9%)
Query: 8 SQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPG-SGHGSESNSSSESSESQSES 66
S E L S S SEE + S SE+E+ P S SE ++S+S++E
Sbjct: 209 SDSESEELPKPQVSDSESEEPPRHQA-SDSENEELPKPRISDSESEDPPRHQASDSENEE 267
Query: 67 ESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKE 126
+ S S+ P + S+ E + + E S+ ++ SR K
Sbjct: 268 LPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKP 327
Query: 127 EASSGSESGSPKRRGQRQLKK--------QEKWKQEPSEDEQEQGTSAESEPEQKKVKAR 178
E+ S+ + + Q ++K+ SE+E+ + +S+ ++K+ +
Sbjct: 328 ESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEE 387
Query: 179 RPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDD-- 236
+ R+ + + K +K + SD DD D +A ++ +R S E++
Sbjct: 388 KVAKRKAAVLSDSEDEEKASA--KKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAG 445
Query: 237 ----DFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDP 292
D + + DL G D + N E E ++ G+ G E G
Sbjct: 446 KELSDKKNEEKDLF-----GSDSESGNEE--ENLIADIFGESGDEEEE------EFTGFN 492
Query: 293 SGDFDTEKDEGEIQ 306
D + EK E +++
Sbjct: 493 QEDLEEEKGETQVK 506
Score = 37.7 bits (86), Expect = 0.025
Identities = 38/176 (21%), Positives = 75/176 (42%), Gaps = 11/176 (6%)
Query: 4 NKDKSQE-EDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSES 62
NK + E ++ S HS++ +S S+ + + SD G E + +
Sbjct: 337 NKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAV 396
Query: 63 QSESE-SESAGSKSQPVLPEAKEKPASKKERIAD-----VKKMWEEYPDVYGVRRSNRSR 116
S+SE E A +K V+ +A + S + ++D K + + + G S++
Sbjct: 397 LSDSEDEEKASAKKSRVVSDADD---SDSDAVSDKSGKREKTIASDSEEEAGKELSDKKN 453
Query: 117 QEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSED-EQEQGTSAESEPE 171
+E F E+ + E+ G+ +++E++ ED E+E+G + E E
Sbjct: 454 EEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGETQVKEAE 509
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 68.2 bits (165), Expect = 2e-11
Identities = 69/297 (23%), Positives = 128/297 (43%), Gaps = 28/297 (9%)
Query: 21 SHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSES-------SESQSESESESAGS 73
SH+ S+ S S S S+ + Q S H S S++ S S S+S + S+S
Sbjct: 310 SHTRSKSRSSSKSHSRRKRSQ-----SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER 364
Query: 74 KSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFN--IKEEASSG 131
+ +++K +E+I + +++ E+ + R R +++ N +E
Sbjct: 365 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 424
Query: 132 SESGSPKRRGQRQLKK------QEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRT 185
E K R + + K+ +EK K++ E E+E+ S E + ++KK K R PR
Sbjct: 425 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 484
Query: 186 VPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDL 245
R + + +R R++ SS + KR++ R + K+D E + D +
Sbjct: 485 NASRRSRSSSRERR--RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 542
Query: 246 IEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDE 302
E +++ S ++ K + R GK+ ST++ E N +P E D+
Sbjct: 543 SER------RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD 593
Score = 54.3 bits (129), Expect = 3e-07
Identities = 49/203 (24%), Positives = 88/203 (43%), Gaps = 18/203 (8%)
Query: 35 SQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIA 94
+QS +P SG +E S ++S+S S S ++ K + K R
Sbjct: 285 AQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKS--------HSRRKRSQSKHRSR 336
Query: 95 DVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQE 154
+ D RRS ++ S+ + ++ S S S ++ + ++K++E+ K++
Sbjct: 337 SHNRSRSRQKDR---RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEK 393
Query: 155 PSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDD 214
E E+E+ E E E+ K K R + K R K + K + +R+K+ E D D
Sbjct: 394 DREKEREREKEREKEKERGKNKDRD----KEREKDREKDKEKDREREREKEH---EKDRD 446
Query: 215 DEAPKRQTRRRAAKNVSYKEDDD 237
E K Q + + + KE D+
Sbjct: 447 KEKEKEQDKEKEREKDRSKEIDE 469
Score = 39.7 bits (91), Expect = 0.006
Identities = 46/223 (20%), Positives = 85/223 (38%), Gaps = 35/223 (15%)
Query: 3 RNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSES 62
+++DK +E+D E+ D + E EQ E + S+
Sbjct: 415 KDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ--------DKEKEREKDRSKE 466
Query: 63 QSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRF 122
E + S++ P + AS++ R + ++ RR +RS R
Sbjct: 467 IDEKRKKDKKSRTPP-----RSYNASRRSRSSSRERR----------RRRSRSSSRSPRT 511
Query: 123 NIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSE-DEQEQGTSAESEPEQKKVKARRPV 181
+ K S S SP+ R ++ KK+EK + SE E+E+ TS + K +
Sbjct: 512 S-KTIKRKSSRSPSPRSRNKKD-KKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 569
Query: 182 PRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRR 224
++ + K+P S ++ DD +AP+ + +
Sbjct: 570 NSTSLKEKEHNKEP---------DSSVSKEVDDKDAPRTEENK 603
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 68.2 bits (165), Expect = 2e-11
Identities = 69/297 (23%), Positives = 128/297 (43%), Gaps = 28/297 (9%)
Query: 21 SHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSES-------SESQSESESESAGS 73
SH+ S+ S S S S+ + Q S H S S++ S S S+S + S+S
Sbjct: 194 SHTRSKSRSSSKSHSRRKRSQ-----SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRER 248
Query: 74 KSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFN--IKEEASSG 131
+ +++K +E+I + +++ E+ + R R +++ N +E
Sbjct: 249 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 308
Query: 132 SESGSPKRRGQRQLKK------QEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRT 185
E K R + + K+ +EK K++ E E+E+ S E + ++KK K R PR
Sbjct: 309 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 368
Query: 186 VPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDL 245
R + + +R R++ SS + KR++ R + K+D E + D +
Sbjct: 369 NASRRSRSSSRERR--RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHI 426
Query: 246 IEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDE 302
E +++ S ++ K + R GK+ ST++ E N +P E D+
Sbjct: 427 SER------RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDD 477
Score = 54.3 bits (129), Expect = 3e-07
Identities = 49/203 (24%), Positives = 88/203 (43%), Gaps = 18/203 (8%)
Query: 35 SQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIA 94
+QS +P SG +E S ++S+S S S ++ K + K R
Sbjct: 169 AQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKS--------HSRRKRSQSKHRSR 220
Query: 95 DVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQE 154
+ D RRS ++ S+ + ++ S S S ++ + ++K++E+ K++
Sbjct: 221 SHNRSRSRQKDR---RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEK 277
Query: 155 PSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDD 214
E E+E+ E E E+ K K R + K R K + K + +R+K+ E D D
Sbjct: 278 DREKEREREKEREKEKERGKNKDRD----KEREKDREKDKEKDREREREKEH---EKDRD 330
Query: 215 DEAPKRQTRRRAAKNVSYKEDDD 237
E K Q + + + KE D+
Sbjct: 331 KEKEKEQDKEKEREKDRSKEIDE 353
Score = 39.7 bits (91), Expect = 0.006
Identities = 46/223 (20%), Positives = 85/223 (38%), Gaps = 35/223 (15%)
Query: 3 RNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSES 62
+++DK +E+D E+ D + E EQ E + S+
Sbjct: 299 KDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ--------DKEKEREKDRSKE 350
Query: 63 QSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRF 122
E + S++ P + AS++ R + ++ RR +RS R
Sbjct: 351 IDEKRKKDKKSRTPP-----RSYNASRRSRSSSRERR----------RRRSRSSSRSPRT 395
Query: 123 NIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSE-DEQEQGTSAESEPEQKKVKARRPV 181
+ K S S SP+ R ++ KK+EK + SE E+E+ TS + K +
Sbjct: 396 S-KTIKRKSSRSPSPRSRNKKD-KKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 453
Query: 182 PRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRR 224
++ + K+P S ++ DD +AP+ + +
Sbjct: 454 NSTSLKEKEHNKEP---------DSSVSKEVDDKDAPRTEENK 487
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 66.6 bits (161), Expect = 5e-11
Identities = 50/201 (24%), Positives = 97/201 (48%), Gaps = 23/201 (11%)
Query: 26 EEASGSDSGSQSE-SEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKE 84
EE D G++S+ +E+G G + E E+++E+E E A +K + + E E
Sbjct: 534 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSE 593
Query: 85 KPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQ 144
+ A+K+E +AD K V + +++ + ++E+ S + +G+
Sbjct: 594 EVATKEELVADAK-----------VEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 642
Query: 145 LKK---QEKWKQE-PSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRG 200
+ K +EK K P +E+G S S+ ++ KA+ PVP+ P K + + +G
Sbjct: 643 VPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEE-KAKSPVPKS--PVEEAKSKAEVGKG 699
Query: 201 KRKKQDSSDEDDDDDEAPKRQ 221
++K+ +E+ + EAPK +
Sbjct: 700 EQKE----EEEKEVKEAPKEE 716
Score = 58.9 bits (141), Expect = 1e-08
Identities = 55/237 (23%), Positives = 91/237 (38%), Gaps = 16/237 (6%)
Query: 52 ESNSSSESSESQSESESESAGSKSQPV---LPEAKEKPASKKERIADVKKMWEEYPDVYG 108
E ++E E + E+E E +K PV PE KE+ K+E ++ EE +
Sbjct: 487 EKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEE--EEEDEGAK 544
Query: 109 VRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAES 168
++ E + KEE + G+ K+EK +E SE+ +
Sbjct: 545 SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVAD 604
Query: 169 EPEQKKVKARRPVPRRTVP---KPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRR 225
+K KA+ PVP+ V K V K P ++GK S E+ PK +
Sbjct: 605 AKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 664
Query: 226 AAKNVS---YKEDDDFETDSDDLIEM-----TGEGVDEQQDNSETIEKVLDSRLGKK 274
VS +E + E G+G ++++ E E + ++ KK
Sbjct: 665 GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKK 721
Score = 50.8 bits (120), Expect = 3e-06
Identities = 87/399 (21%), Positives = 149/399 (37%), Gaps = 86/399 (21%)
Query: 3 RNKDKSQEEDSSLHSNASSHSASE---EASGSDSGSQSESEQGSDPGSGHGSESNSSSES 59
+ +++ QEE+ A S A E E GS + E E+G G E+ + E
Sbjct: 527 KEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEK 586
Query: 60 SESQSESESESAGSKSQPVLPEAKEKPASKKERI-------------------------- 93
+ E +SE +K + V EKP K +
Sbjct: 587 ---KVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 643
Query: 94 ----------ADVKKMWEEYPDVYGVRRS--NRSRQEPSRFNIKEEASSGSESGSPKRRG 141
+ V K E V +S + P + EEA S +E G +G
Sbjct: 644 PKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVG----KG 699
Query: 142 QRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVP---------KPRVK 192
+++ +++++ K+ P E++ E+ + +KK KA PV V K ++
Sbjct: 700 EQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKK-KAESPVKEEAVAEVVTITKSVKVHLE 758
Query: 193 KQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEG 252
K+ K + GK +Q+ E + + + + AK S KED I + GE
Sbjct: 759 KETK-EEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKG-SRKED----------IAVNGEV 806
Query: 253 VDEQQDNSETIEKVLDSRLGKKG--ATGASTTVYAIEANGDPSGD----------FDTEK 300
+++ ET EK R +KG G + + GD S + +E
Sbjct: 807 EGKEEVEQETKEKG-SGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 865
Query: 301 DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLE 339
+G +Y+ K + E EE+ ++K+ KK+E
Sbjct: 866 GDGATKYIT--KSVTVTQKVEEHEETF-EEKLVSTKKVE 901
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 66.6 bits (161), Expect = 5e-11
Identities = 50/201 (24%), Positives = 97/201 (48%), Gaps = 23/201 (11%)
Query: 26 EEASGSDSGSQSE-SEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKE 84
EE D G++S+ +E+G G + E E+++E+E E A +K + + E E
Sbjct: 158 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSE 217
Query: 85 KPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQ 144
+ A+K+E +AD K V + +++ + ++E+ S + +G+
Sbjct: 218 EVATKEELVADAK-----------VEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 266
Query: 145 LKK---QEKWKQE-PSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRG 200
+ K +EK K P +E+G S S+ ++ KA+ PVP+ P K + + +G
Sbjct: 267 VPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEE-KAKSPVPKS--PVEEAKSKAEVGKG 323
Query: 201 KRKKQDSSDEDDDDDEAPKRQ 221
++K+ +E+ + EAPK +
Sbjct: 324 EQKE----EEEKEVKEAPKEE 340
Score = 58.9 bits (141), Expect = 1e-08
Identities = 55/237 (23%), Positives = 91/237 (38%), Gaps = 16/237 (6%)
Query: 52 ESNSSSESSESQSESESESAGSKSQPV---LPEAKEKPASKKERIADVKKMWEEYPDVYG 108
E ++E E + E+E E +K PV PE KE+ K+E ++ EE +
Sbjct: 111 EKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEE--EEEDEGAK 168
Query: 109 VRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAES 168
++ E + KEE + G+ K+EK +E SE+ +
Sbjct: 169 SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVAD 228
Query: 169 EPEQKKVKARRPVPRRTVP---KPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRR 225
+K KA+ PVP+ V K V K P ++GK S E+ PK +
Sbjct: 229 AKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 288
Query: 226 AAKNVS---YKEDDDFETDSDDLIEM-----TGEGVDEQQDNSETIEKVLDSRLGKK 274
VS +E + E G+G ++++ E E + ++ KK
Sbjct: 289 GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKK 345
Score = 50.8 bits (120), Expect = 3e-06
Identities = 87/399 (21%), Positives = 149/399 (37%), Gaps = 86/399 (21%)
Query: 3 RNKDKSQEEDSSLHSNASSHSASE---EASGSDSGSQSESEQGSDPGSGHGSESNSSSES 59
+ +++ QEE+ A S A E E GS + E E+G G E+ + E
Sbjct: 151 KEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEK 210
Query: 60 SESQSESESESAGSKSQPVLPEAKEKPASKKERI-------------------------- 93
+ E +SE +K + V EKP K +
Sbjct: 211 ---KVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 267
Query: 94 ----------ADVKKMWEEYPDVYGVRRS--NRSRQEPSRFNIKEEASSGSESGSPKRRG 141
+ V K E V +S + P + EEA S +E G +G
Sbjct: 268 PKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVG----KG 323
Query: 142 QRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVP---------KPRVK 192
+++ +++++ K+ P E++ E+ + +KK KA PV V K ++
Sbjct: 324 EQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKK-KAESPVKEEAVAEVVTITKSVKVHLE 382
Query: 193 KQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEG 252
K+ K + GK +Q+ E + + + + AK S KED I + GE
Sbjct: 383 KETK-EEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKG-SRKED----------IAVNGEV 430
Query: 253 VDEQQDNSETIEKVLDSRLGKKG--ATGASTTVYAIEANGDPSGD----------FDTEK 300
+++ ET EK R +KG G + + GD S + +E
Sbjct: 431 EGKEEVEQETKEKG-SGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 489
Query: 301 DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLE 339
+G +Y+ K + E EE+ ++K+ KK+E
Sbjct: 490 GDGATKYIT--KSVTVTQKVEEHEETF-EEKLVSTKKVE 525
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 63.5 bits (153), Expect = 4e-10
Identities = 55/266 (20%), Positives = 86/266 (32%), Gaps = 5/266 (1%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQ 63
+ D S DSS S++ S S+ E+ SDS S+S+S + S S+S+ SS SS S
Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 64 SESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFN 123
S+S + S + +S +D E + + S N
Sbjct: 667 DSSDSSDSSDSSS----SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN 722
Query: 124 IKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPR 183
+ SS S S + S D + S++S +
Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782
Query: 184 RTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSD 243
+SSD D D + + + N S D +DS
Sbjct: 783 SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS 842
Query: 244 DLIEMTGEGVDEQQDNSETIEKVLDS 269
D + + +G D N DS
Sbjct: 843 DSSD-SSDGSDSDSSNRSDSSNSSDS 867
Score = 62.4 bits (150), Expect = 9e-10
Identities = 62/303 (20%), Positives = 105/303 (34%), Gaps = 4/303 (1%)
Query: 3 RNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSES 62
+ K S + DSS SN+S S S ++ SDS S S+S+ SD S S+S+SS S+ S
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSD-SSDSDSSDSSDSDSSDSSNSS 602
Query: 63 QSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRF 122
S S+S+ S ++K +SK E + + D S+ S S
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSK-SDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 123 NIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVP 182
+ SS S S + S + E S++S +
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Query: 183 RRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRA-AKNVSYKEDDDFETD 241
+ DSSD + D + + + + + S D ++
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 242 SDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKD 301
S D + + NS DS ++ + ++ + +N S D D
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSS-DSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840
Query: 302 EGE 304
+
Sbjct: 841 SSD 843
Score = 60.1 bits (144), Expect = 5e-09
Identities = 57/303 (18%), Positives = 101/303 (33%), Gaps = 12/303 (3%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE-S 62
+ D S + S+ +++S +S+ ++ SDS S+S GSD S + S+S++SS+SS+ S
Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871
Query: 63 QSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRF 122
S + S+S+ S + + S +D S+ S S
Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Query: 123 NIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVP 182
N SS S S S D + +S S+ +
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS----- 986
Query: 183 RRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRA-AKNVSYKEDDDFETD 241
DSSD D D + + + + N S D +D
Sbjct: 987 -----DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Query: 242 SDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKD 301
S D + + +S DS + + ++ + ++ S D D
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101
Query: 302 EGE 304
+
Sbjct: 1102 SSD 1104
Score = 54.3 bits (129), Expect = 3e-07
Identities = 50/269 (18%), Positives = 84/269 (31%), Gaps = 4/269 (1%)
Query: 8 SQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESE 67
S + DSS S++ S +S + SDS S+S SD S S S+SS+S S+S+
Sbjct: 582 SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641
Query: 68 SESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEE 127
S + S ++ + S + + S+ S N E
Sbjct: 642 SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701
Query: 128 A----SSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPR 183
+ SS S+S + S D S++S +
Sbjct: 702 SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 761
Query: 184 RTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSD 243
DS+D + D + + + + S D ++DS
Sbjct: 762 SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821
Query: 244 DLIEMTGEGVDEQQDNSETIEKVLDSRLG 272
+ + + NS DS G
Sbjct: 822 NSSDSSNSSDSSDSSNSSDSSDSSDSSDG 850
Score = 53.5 bits (127), Expect = 4e-07
Identities = 54/296 (18%), Positives = 99/296 (33%), Gaps = 4/296 (1%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQG-SDPGSGHGSESNSSSESSES 62
N D + + S++S +S+ ++ SDS S+S+ S+ S S + SS+SS+S
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS 593
Query: 63 QSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRF 122
S S S+ S ++ + S + +D K + D S+ S S
Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSK-SDSSKSESDSSDSDSKSDSSDSNSSDSSD 652
Query: 123 NIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVP 182
N SS S + S S D + S+ S +
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS 712
Query: 183 RRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDS 242
+ DSS+ D D + + + + S D +DS
Sbjct: 713 SDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSD--SSDS 770
Query: 243 DDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDT 298
D + + ++S DS + + ++ + ++ D S D+
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS 826
Score = 52.4 bits (124), Expect = 1e-06
Identities = 53/260 (20%), Positives = 81/260 (31%), Gaps = 27/260 (10%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQ 63
+ D S DSS SN+S S S ++S S S S S S SNSS S S
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101
Query: 64 SESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFN 123
S S+S+ S + +S +D + S+ S S +
Sbjct: 1102 SSDSSDSSDSSD-----SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDS 1156
Query: 124 IKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPR 183
SS S S + S D + S++S
Sbjct: 1157 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD------------- 1203
Query: 184 RTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRA-AKNVSYKEDDDFETDS 242
DSSD D D + ++ + + + S + +DS
Sbjct: 1204 --------SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255
Query: 243 DDLIEMTGEGVDEQQDNSET 262
D + T + DE S++
Sbjct: 1256 SDSSDSTSDSNDESDSQSKS 1275
Score = 51.2 bits (121), Expect = 2e-06
Identities = 60/301 (19%), Positives = 98/301 (32%), Gaps = 24/301 (7%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGS--QSESEQGSDPGSGHGSESNSSSESSE 61
N D + ++ N S S ++ SDS S S S SD S+SNSSS+S
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDS 582
Query: 62 SQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSR 121
S S+S S+S+ S S + +S +D + D S++S + S
Sbjct: 583 SDSDS-SDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD------SSKSESDSSD 635
Query: 122 FNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPV 181
+ K ++S + S S S D S++S +
Sbjct: 636 SDSKSDSSDSNSSDSS--------------DNSDSSDSSNSSNSSDSSDSSDSSDSSSSS 681
Query: 182 PRRTVPKPRVKKQPKTQRGKRKKQDSSDED-DDDDEAPKRQTRRRAAKNVSYKEDDDFET 240
DSSD D D ++ + + N S D +
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741
Query: 241 DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK 300
DS D + + +S DS + ++++ +N S D
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801
Query: 301 D 301
D
Sbjct: 802 D 802
Score = 47.0 bits (110), Expect = 4e-05
Identities = 26/68 (38%), Positives = 40/68 (58%), Gaps = 2/68 (2%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASG--SDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
+ D S DSS SN+S S S ++S SDS +S+S+ S G+ +GS+S+S SE S+
Sbjct: 1234 SSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSD 1293
Query: 62 SQSESESE 69
S + +
Sbjct: 1294 SNHSTSDD 1301
Score = 45.8 bits (107), Expect = 9e-05
Identities = 58/308 (18%), Positives = 103/308 (33%), Gaps = 18/308 (5%)
Query: 7 KSQEEDSSLHSNASSHSASE----------EASGSDSGSQSESEQGSDPGSGHGSESNSS 56
KS+ + HSN S S S+ G D S ES D S S++NSS
Sbjct: 429 KSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANS--ESDNNSS 486
Query: 57 SESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPD-----VYGVRR 111
S S + ES+ G+ S E + ++ +D D G +
Sbjct: 487 SRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGK 546
Query: 112 SNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPE 171
S+ S + S + ++S S+S S + + S+ + +++ +
Sbjct: 547 SDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD 606
Query: 172 QKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVS 231
+ K K K DSSD + D + + N S
Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 232 YKEDDDFETDSDDLIEMTGEG-VDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANG 290
D +DS + + + D+S + E S ++ +S + + ++
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Query: 291 DPSGDFDT 298
D S D+
Sbjct: 727 DSSNSSDS 734
Score = 45.8 bits (107), Expect = 9e-05
Identities = 52/312 (16%), Positives = 106/312 (33%), Gaps = 39/312 (12%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGS-------------GHG 50
N D + E D++ S + S+E+ + +GS S+ + D S +G
Sbjct: 474 NDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNG 533
Query: 51 SESNSSSESSESQSE-SESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGV 109
++ N S+S + +S+ S+S+S+ S + ++ + +S +D + D
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS 593
Query: 110 RRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESE 169
S+ S N + + S S S K + S D + S++S
Sbjct: 594 DSSDSS-------NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSN 646
Query: 170 PEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKN 229
+ DSSD D D + + + +
Sbjct: 647 SSDSSDNS----------------DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN--SSD 688
Query: 230 VSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEAN 289
S D ++S D + + + D+S + DS + ++++ + ++
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 290 GDPSGDFDTEKD 301
S D D
Sbjct: 749 SSNSSDSSDSSD 760
Score = 43.1 bits (100), Expect = 6e-04
Identities = 75/353 (21%), Positives = 129/353 (36%), Gaps = 81/353 (22%)
Query: 11 EDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESE- 69
ED+ L ++ S S + G+D S D +G+G +S+++S+ E Q + +
Sbjct: 235 EDAGLDNSDGSPSGN----GADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDD 290
Query: 70 ---SAGSKS---QPVLPEAKEKP--------ASKKE-------------RIADVKKMWEE 102
S G S + PE KE P SK E RI D +K+
Sbjct: 291 HDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHR 350
Query: 103 YPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQE- 161
R NR +E + + G E P G R + K+ E ED+ +
Sbjct: 351 ----ESKRVENRITKESETHAVGKSQDKGIEIKGPS-SGNRNITKEVGKGNEGKEDKGQH 405
Query: 162 ------------------QGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRK 203
+G +SEP K + + K+ +G
Sbjct: 406 GMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQG--D 463
Query: 204 KQDSSDEDDDDDEAPKRQTRRRAAK-NVSYK----------------EDDDFETDSD-DL 245
+SSDE + +D+A +++ + SY EDDD ++ SD +
Sbjct: 464 DPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523
Query: 246 IEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDT 298
+ G G + DN ++ DS GK ++ + ++ + ++ S D D+
Sbjct: 524 SDSNGNGNNGNDDNDKS-----DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 63.2 bits (152), Expect = 5e-10
Identities = 64/262 (24%), Positives = 112/262 (42%), Gaps = 16/262 (6%)
Query: 3 RNKDKSQEEDSSLHSNASSHSA-SEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
R++ +S+ S + SS S+ S+ S S SGS+S S+ S S S+ S S+
Sbjct: 193 RSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSK 252
Query: 62 SQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSR 121
+S S S SAG ++K++ K + +V K P + + +RSR + R
Sbjct: 253 EKSRSRSHSAGKSRS----KSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERR 308
Query: 122 FNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPV 181
EE GS S + R Q + +Q + + + + S +++K + R
Sbjct: 309 V---EEEKRGSVS---RGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSRE 362
Query: 182 PRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETD 241
R+ + R K + +RG ++ + E R R +++VS KE + +++
Sbjct: 363 ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVS-KEREHAKSE 421
Query: 242 SDDLIEMTGEGVDEQQ-DNSET 262
S + G G E N ET
Sbjct: 422 SS---QREGRGESENAGTNQET 440
Score = 43.1 bits (100), Expect = 6e-04
Identities = 50/207 (24%), Positives = 84/207 (40%), Gaps = 15/207 (7%)
Query: 3 RNKDKSQEEDSSLHSNAS-SHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
+++ +SQE S S S+E S S S+S S+ GS S S+S + +
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358
Query: 62 SQSESESESAGSKSQPVLPEAKEKPASKKE-RIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
E + S+S+ E K SK++ + KK +E D R +RS PS
Sbjct: 359 RSREESRSRSRSRSKS---ERSRKRGSKRDSKAGSSKKKKKEDTD----RSQSRS---PS 408
Query: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
R KE + SES + RG+ + QE + S + P + + +++
Sbjct: 409 RSVSKEREHAKSESSQREGRGE---SENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSA 465
Query: 181 VPRRTVPKPRVKKQPKTQRGKRKKQDS 207
R+ K R + ++ R + S
Sbjct: 466 SKTRSRSKSRSRSASRSPSRSRSRSHS 492
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 62.4 bits (150), Expect = 9e-10
Identities = 71/284 (25%), Positives = 113/284 (39%), Gaps = 48/284 (16%)
Query: 17 SNASSHSASEEASGSDSGSQSESE---QGSDPGSGHGSESNSSSESSESQSESESESAGS 73
+ AS S+SEE+S D + + +G P + ++SS+S S+S SE
Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPP 180
Query: 74 KSQ-----PVLPEAKEK----PASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNI 124
K+Q PV +A+ K PA +IA+ K S+ S S +
Sbjct: 181 KNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSS---------SSSSSSSSSDDSE 231
Query: 125 KEEASSGSESGSPKRRGQRQLKKQEKWKQEPS-EDEQEQGTSAESEPEQKKVKARRPVPR 183
+E+A++ + PK+ Q K K P+ + + +S++ E EQKK +P P
Sbjct: 232 EEKAAATPKKTVPKK--QVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPY 289
Query: 184 RTVPKPRV------------KKQPKTQRGKRKKQDSSDEDDDDDEAPKR----------Q 221
+VP P KK + Q+ +DSSDE D E K+
Sbjct: 290 SSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKAT 349
Query: 222 TRRRAAKNVSYKEDDDFETDS--DDLIEMTGEGVDEQQDNSETI 263
T+ AK + D ++DS DD G + N +
Sbjct: 350 TKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAV 393
Score = 58.2 bits (139), Expect = 2e-08
Identities = 56/225 (24%), Positives = 89/225 (39%), Gaps = 16/225 (7%)
Query: 6 DKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSE 65
+K Q +SS S+ S S+SEE + + P + +ES+S S S+S
Sbjct: 314 EKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDS--- 370
Query: 66 SESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIK 125
SE + A SK + KPA + A + P G + R S +
Sbjct: 371 SEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSS---E 427
Query: 126 EEASSGSESGS--------PKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVK- 176
EE+SS E + PK + L K + S D S+ SE E++K
Sbjct: 428 EESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSK 487
Query: 177 -ARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKR 220
A + P++ K ++GK + +SS DD +E ++
Sbjct: 488 SAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEK 532
Score = 46.2 bits (108), Expect = 7e-05
Identities = 51/237 (21%), Positives = 87/237 (36%), Gaps = 17/237 (7%)
Query: 8 SQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGS------GHGSESNSSSESSE 61
S + DSS A S A + S+ + + P + G G + + S
Sbjct: 365 SSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSS 424
Query: 62 SQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSR 121
S E S S K++ ++ K K +K K+ + G R S+ S
Sbjct: 425 SSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQ------GSRDSSSDSDSSSS 478
Query: 122 FNIKEEASSGSESGSPKR-RGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
+E+ S + P++ G K K+ +E + SE E++K+K +
Sbjct: 479 EEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGS 538
Query: 181 VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEA---PKRQTRRRAAKNVSYKE 234
PR PK Q GK K +E++ A K + ++ +N + KE
Sbjct: 539 -PRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKE 594
Score = 42.4 bits (98), Expect = 0.001
Identities = 47/192 (24%), Positives = 74/192 (38%), Gaps = 26/192 (13%)
Query: 4 NKDKSQEEDSSL---HSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60
++D S + DSS +S SA ++ +G + S+ S G SNSSS
Sbjct: 466 SRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAK-KGKAESSNSSSSDD 524
Query: 61 ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
S+ E E +P P+A A + G N +E
Sbjct: 525 SSEEEEEKLKGKGSPRPQAPKANGTSALTAQN---------------GKAAKNSEEEEEE 569
Query: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
+ K+ A S+SGS K+R Q + K+ + Q Q T P++KK + R
Sbjct: 570 K---KKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTF----PKRKKGEKRAS 622
Query: 181 VPRRTVPKPRVK 192
P R V + ++
Sbjct: 623 SPFRRVREEEIE 634
Score = 40.4 bits (93), Expect = 0.004
Identities = 49/225 (21%), Positives = 80/225 (35%), Gaps = 31/225 (13%)
Query: 103 YPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGS---------------PKRRGQRQLKK 147
YP V G R N+ + ++F A+ + S P+R+ Q
Sbjct: 15 YPLVLGFLRDNQLSEVANKFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPV 74
Query: 148 QEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDS 207
+K K++ S + E + E E + P + VP RV P K + S
Sbjct: 75 AKKAKKKASSSDSEDSSEEEEEVQGP------PAKKAAVPAKRVGLPPGKAAAKASESSS 128
Query: 208 SDED--DDDDEAPKRQTRRRAAK------NVSYKEDDDFETDSDDLIEMTGEGVDEQQDN 259
S+E DDD+E K+Q ++ K K+ ++DSD E E Q+
Sbjct: 129 SEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSE--DEPPKNQKPK 186
Query: 260 SETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGE 304
+ ++ K A A A+ S + D+ E
Sbjct: 187 ITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSE 231
Score = 39.7 bits (91), Expect = 0.006
Identities = 55/246 (22%), Positives = 91/246 (36%), Gaps = 37/246 (15%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQ 63
+ S+EE SS + + + + + P S S+S S SSE +
Sbjct: 422 DSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEE 481
Query: 64 SESESESAGSKSQPVLP--EAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSR 121
E S+SA K + A KPAS K+ G S+ S
Sbjct: 482 EEKTSKSAVKKKPQKVAGGAAPSKPASAKK----------------GKAESSNSSSSDDS 525
Query: 122 FNIKEEASSGSESG---SPKRRGQRQLKKQE-KWKQEPSEDEQEQGTSAESEPEQKKVKA 177
+EE G S +PK G L Q K + E+E+E+ +A + +K
Sbjct: 526 SEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKK 585
Query: 178 RRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTR-RRAAKNVSYKEDD 236
R+ + K+ +T + K+ K + + PKR+ +RA+ ++
Sbjct: 586 RK--------QNEAAKEAETPQAKKIKLQTPNT------FPKRKKGEKRASSPFRRVREE 631
Query: 237 DFETDS 242
+ E DS
Sbjct: 632 EIEVDS 637
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 62.0 bits (149), Expect = 1e-09
Identities = 75/352 (21%), Positives = 134/352 (38%), Gaps = 78/352 (22%)
Query: 8 SQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS------- 60
+QE + H+ S SA E ++ + SE+G G G G E N E++
Sbjct: 1769 AQEREGKTHN--SETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDP 1826
Query: 61 ----------------ESQSESE----------SESAGSKSQP-----VLPEAKEKPASK 89
E+Q ESE ++ A ++QP PEA+ + +
Sbjct: 1827 GQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPE 1886
Query: 90 KERIADVKKMWEEYPDVYGVRRSNRSRQ-EPSRFNIKEEASSGSE----SGSPKRRGQRQ 144
E + + WE P+ G ++ +P +++ + G + G+ + +
Sbjct: 1887 SEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEA 1946
Query: 145 LKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKK 204
++ E Q SE + Q E++PE + V+A ++ + +TQ + +
Sbjct: 1947 AQEAEGQTQPESEVIESQEAEEEAQPESEDVEA-------------LEVEVETQEAEGEA 1993
Query: 205 QDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIE 264
Q S +D EAP+ + + A+ + E D E + EG + Q+ ET +
Sbjct: 1994 QPES----EDVEAPEAEGEMQEAEEEAQPESDGVEA------QPKSEGEEAQEVEGETQK 2043
Query: 265 KVLDSRLGKKGATGASTTVYAIEANGD----------PSGDFDTEKDEGEIQ 306
D++ G A EA G+ S D D ++ EGE Q
Sbjct: 2044 TEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQ 2095
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/321 (20%), Positives = 128/321 (39%), Gaps = 29/321 (9%)
Query: 7 KSQEEDSSLHSNASSHSASEEASGSDSGSQSESE--------QGSDPGSGHGSESNSSSE 58
+++ ED A + A E A ++ +Q ESE + + P S E
Sbjct: 1926 ETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVE 1985
Query: 59 SSESQSESESESA---GSKSQPVLPEAKEKPASKKERI-ADVKKMWEEYPDVYGVRRSNR 114
+ E++ E++ ES +++ + EA+E+ + + + A K EE +V G +
Sbjct: 1986 TQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTE 2045
Query: 115 SRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKK 174
+P + + E+ + + ++++ E SED Q E++PE +
Sbjct: 2046 GDAQP-----ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEG 2100
Query: 175 VKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQ--TRRRAAKNVSY 232
V+A P K + P+T+ + + + + + + EA + A+ +
Sbjct: 2101 VEA--PEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQ 2158
Query: 233 KEDDDFET-DSDDLIEMTGEGVD------EQQDNSETIEKVLDSRLGKKGATGASTTVYA 285
E + E ++++ + EGV+ E Q SE IE + G
Sbjct: 2159 PESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAE 2218
Query: 286 IEANGDPSGDFDTEKDEGEIQ 306
EA +P G +T + EGE Q
Sbjct: 2219 EEAQPEPEG-VETPEAEGEAQ 2238
Score = 38.9 bits (89), Expect = 0.011
Identities = 45/223 (20%), Positives = 86/223 (38%), Gaps = 10/223 (4%)
Query: 2 MRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSES-- 59
+ + + E D+ S+ +EE + G E+E + P S + E+
Sbjct: 2037 VEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQP 2096
Query: 60 -SESQSESESESAGSKSQPV-LPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSN-RSR 116
SE E+E K++ + PE + + + E I + E P+ GV +
Sbjct: 2097 ESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGE 2156
Query: 117 QEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVK 176
+P I EA E P+ G + + E Q SE + E++PE + V+
Sbjct: 2157 AQPESEGI--EAQEAEEEAQPELEGV-EAPEAEGEAQPESEGIEAPEAEGEAQPELEGVE 2213
Query: 177 ARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPK 219
A P+P + P+ + G+ + + + + +P+
Sbjct: 2214 APE-AEEEAQPEPEGVETPEAE-GEAQPESEGETQGEKKGSPQ 2254
Score = 32.3 bits (72), Expect = 1.0
Identities = 59/278 (21%), Positives = 97/278 (34%), Gaps = 47/278 (16%)
Query: 24 ASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSES----------------- 66
A EA ++ E+E + P S G E+ + E+Q ES
Sbjct: 2106 AEGEAQKAEGIEAPETEGEAQPES-EGIEAPEAE--GEAQPESEGVEAQDAEGEAQPESE 2162
Query: 67 --ESESAGSKSQPVL-----PEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQ-E 118
E++ A ++QP L PEA+ + + E I + E P++ GV + +
Sbjct: 2163 GIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQ 2222
Query: 119 PSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKAR 178
P ++ + G P+ G+ Q +K+ Q D Q + S S P +
Sbjct: 2223 PEPEGVETPEAEG--EAQPESEGETQGEKKGS-PQVSLGDGQSEEASESSSPVPEDRPTP 2279
Query: 179 RPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVS------- 231
P P P R Q + + + D +++ TR AK+
Sbjct: 2280 PPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERK 2339
Query: 232 ----YKEDDDFETDSDDLIEMT-----GEGVDEQQDNS 260
Y E E + L T EG D Q+D +
Sbjct: 2340 ATRMYPESSTSEQEEAPLGSRTPEQGASEGYDLQEDQA 2377
Score = 31.6 bits (70), Expect = 1.8
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 13/77 (16%)
Query: 10 EEDSSLHSNAS--SHSASEEASGSDSG---------SQSESEQGSDPGSGHGSESNSSSE 58
EE +S S+AS SH S E G G SQ E+ +G DP S S S+ S+
Sbjct: 528 EEGASSDSSASTGSHEGSSEWGGRPQGCPGKARAETSQQEASEGGDPASPALSLSSLRSD 587
Query: 59 --SSESQSESESESAGS 73
+E+Q + ++ G+
Sbjct: 588 DLQAETQGQGTEQATGA 604
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 61.2 bits (147), Expect = 2e-09
Identities = 50/154 (32%), Positives = 69/154 (44%), Gaps = 7/154 (4%)
Query: 3 RNK-DKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
RNK KS+ SS S++SS ++S S S SGS S S S GS S SS S+
Sbjct: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS 626
Query: 62 SQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYG--VRRSNRSRQEP 119
S SES S S G + K + + ++R D + + G R + S+ +
Sbjct: 627 SSSESRSRSRGRGHN---RDRKHRRSVDRKR-RDTSGLERSHKSSKGGSSRDTKGSKDKN 682
Query: 120 SRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQ 153
SR + K S S SG R +R K K K+
Sbjct: 683 SRSDRKRSISESSRSGKRSSRSERDRKSDRKDKR 716
Score = 38.9 bits (89), Expect = 0.011
Identities = 39/162 (24%), Positives = 65/162 (40%), Gaps = 11/162 (6%)
Query: 22 HSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPE 81
H S+ + + S S+ + + S S+SSS SS S S S S+GS S
Sbjct: 549 HPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSS 608
Query: 82 AKEKP--ASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSG-------S 132
+ +S ++ + E G R NR R+ + K +SG S
Sbjct: 609 SSSSTSGSSSRDSSSSTSSSSESRSRSRG-RGHNRDRKHRRSVDRKRRDTSGLERSHKSS 667
Query: 133 ESGSPK-RRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQK 173
+ GS + +G + + K+ SE + S+ SE ++K
Sbjct: 668 KGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
Score = 37.0 bits (84), Expect = 0.042
Identities = 57/286 (19%), Positives = 108/286 (37%), Gaps = 30/286 (10%)
Query: 1 MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSE-SNSSSES 59
++RN+++ E++ A E ++G+Q + + G E + S++
Sbjct: 297 VVRNEEQKAEQEEG-------KVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDA 349
Query: 60 SESQSESESE---SAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYG---VRRSN 113
+ Q E E + + + + E++++ S+ E + DV +M E V V +N
Sbjct: 350 EKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETN 409
Query: 114 RSRQ-EPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQ 172
R EPS +E E +++ ++ K E E E E+
Sbjct: 410 RVESVEPSENEASKELEPEMEF---------EIEPDKECKSLSPGKENVSALDMEKESEE 460
Query: 173 KKVKARRPVPRRTVPKPRVKKQPKTQRGKRKK---QDSSDEDDDDDEAPKRQTRRRAAKN 229
K+ K P P V +P+ + QP+ Q + + Q +D Q + +
Sbjct: 461 KEEKESEPQP-EPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQE 519
Query: 230 VSY--KEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGK 273
+ E DF +S L E+ E V S++ K G+
Sbjct: 520 QGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGR 565
Score = 33.5 bits (75), Expect = 0.46
Identities = 55/271 (20%), Positives = 95/271 (35%), Gaps = 44/271 (16%)
Query: 10 EEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSES-------NSSSESSES 62
+E SL + SA + S+ + ESE +P + +S + S +S
Sbjct: 437 KECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQS 496
Query: 63 QSESESESAG-SKSQP----------VLPEAKEKPA-SKKERIADVKKMWEEYPDVYGV- 109
Q S+ E + QP +LPE K+ P S K V+ + +P+
Sbjct: 497 QPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKT 556
Query: 110 -----------RRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSED 158
++++SR S + +S+ S SGS G + S
Sbjct: 557 KTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGS 616
Query: 159 EQEQGTSAESEPEQKKV-----------KARRPVPRRTVPKPRVKKQPKTQRG--KRKKQ 205
+S+ S + + K RR V R+ +++ K+ +G R +
Sbjct: 617 SSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTK 676
Query: 206 DSSDEDDDDDEAPKRQTRRRAAKNVSYKEDD 236
S D++ D R+ K S E D
Sbjct: 677 GSKDKNSRSDRKRSISESSRSGKRSSRSERD 707
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 60.8 bits (146), Expect = 3e-09
Identities = 58/306 (18%), Positives = 117/306 (38%), Gaps = 19/306 (6%)
Query: 12 DSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESA 71
D + S + S E G + E+GS E E + + E E
Sbjct: 632 DKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE 691
Query: 72 GSKSQPVLPEAKEKPASK-----------KERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
G K E K++ + KER ++++ EE +R +E
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEK 751
Query: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARR- 179
KEE G ++ + K++ K+E E+E +QG E E E + +
Sbjct: 752 EGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEG 811
Query: 180 -PVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDF 238
V V + + +++ + + G+ ++++ E+++ + + + + + +++
Sbjct: 812 GEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEG 871
Query: 239 ETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDT 298
E + E GEG E++ E E+ + G++ G E G+ G+ +
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE-GEEEGEGEGE-----EEEGEGKGEEEG 925
Query: 299 EKDEGE 304
E+ EGE
Sbjct: 926 EEGEGE 931
Score = 54.3 bits (129), Expect = 3e-07
Identities = 59/304 (19%), Positives = 108/304 (35%), Gaps = 44/304 (14%)
Query: 10 EEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESE 69
E++ + E G E E+G + G G E E E + E E +
Sbjct: 698 EKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDRE-EEEEKEGEGK 756
Query: 70 SAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEAS 129
G + KE+ KKE A ++ EE D +E + +E+
Sbjct: 757 EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGD------QGEGEEEETEGRGEEKEE 810
Query: 130 SGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKP 189
G G G+ + +++E E E E+E+G E E E ++
Sbjct: 811 GGEVEGGEVEEGKGEREEEE----EEGEGEEEEGEGEEEEGEGEE--------------- 851
Query: 190 RVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMT 249
+ G+ K ++ +E + ++E + + + E + E + E
Sbjct: 852 --------EEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG----EGEGEEEGEGEGEEEE 899
Query: 250 GEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLI 309
GEG E++ E E+ + + ++G G G+ + E++EGE
Sbjct: 900 GEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE----- 954
Query: 310 KWKG 313
W+G
Sbjct: 955 -WEG 957
Score = 52.0 bits (123), Expect = 1e-06
Identities = 50/291 (17%), Positives = 106/291 (36%), Gaps = 6/291 (2%)
Query: 6 DKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSE 65
++ +EE+ EE G + + + E+ + G G E E + E
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 66 SESESAG---SKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRF 122
E E G + + E +E+ + E K EE + G E
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG 944
Query: 123 NIKEEASSGSESGSPKR-RGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPV 181
+ E G G + G+ + + + + ++ E E+E+G E E ++
Sbjct: 945 EGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE 1004
Query: 182 PRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETD 241
+++ G+ + ++ E ++++ + + R + + + + + E +
Sbjct: 1005 GEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEE 1064
Query: 242 SDDLIEMTGEGVDEQQDNSE--TIEKVLDSRLGKKGATGASTTVYAIEANG 290
+ + TGE +E+QD E + K+ S K T +V + NG
Sbjct: 1065 EEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNG 1115
Score = 50.8 bits (120), Expect = 3e-06
Identities = 63/344 (18%), Positives = 128/344 (37%), Gaps = 26/344 (7%)
Query: 9 QEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESES 68
+EE EE G + + E E+G + E + E
Sbjct: 740 EEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEE 799
Query: 69 ESAG---SKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIK 125
E+ G K + E E K ER EE + G +E +
Sbjct: 800 ETEGRGEEKEEGGEVEGGEVEEGKGER-------EEEEEEGEGEEEEGEGEEEEGEGEEE 852
Query: 126 EEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRT 185
E G E G + + + + ++E E E E+ E E E+ + +
Sbjct: 853 EGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEG-------- 904
Query: 186 VPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDL 245
+ + + + + G+ K ++ +E + + E + + + +E+ ++E + +
Sbjct: 905 --EEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE-- 960
Query: 246 IEMTGEGVDEQQDNSETIEKVLDSRLGK-KGATGASTTVYAIEANGDPSGDFD-TEKDEG 303
E GEG +E + E E + G+ +G E G+ G+ + E++EG
Sbjct: 961 -EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEG 1019
Query: 304 EIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDE 347
E++ ++ + E EE ++++ +G + EN + +E+E
Sbjct: 1020 EVEGEVEGEEGEGEGEEEEGEEEGEEREKEG-EGEENRRNREEE 1062
Score = 46.6 bits (109), Expect = 5e-05
Identities = 52/291 (17%), Positives = 106/291 (36%), Gaps = 24/291 (8%)
Query: 3 RNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHG------------ 50
+ +++ +E + EE + + E E + G G G
Sbjct: 857 KGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Query: 51 SESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVR 110
E E E + E E E + + E +E+ + + + EE + G
Sbjct: 917 GEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEE 976
Query: 111 RSNRSRQEPSRFNIKEE--ASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAES 168
+E +EE G E G + G+ + +++E+ + E E E E+G
Sbjct: 977 GEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVE-GEVEGEEGEGEGE 1035
Query: 169 EPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAK 228
E E ++ R R +++ + + GK ++ + + D E K+ ++ +
Sbjct: 1036 EEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKG-- 1093
Query: 229 NVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGA 279
+V Y + ++ S + G G +++ V RL K G +G+
Sbjct: 1094 SVKYGKHKTYQKKS--VTNTQGNGKEQRSK-----MPVQSKRLLKNGPSGS 1137
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 60.8 bits (146), Expect = 3e-09
Identities = 81/371 (21%), Positives = 150/371 (40%), Gaps = 39/371 (10%)
Query: 20 SSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVL 79
S H AS SGS+S S SD S G + S S + + E +S+
Sbjct: 5 SRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR--- 61
Query: 80 PEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKR 139
++++ ++ R + + E RR +RSR SR +S G++S +
Sbjct: 62 --SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSR---SRGRRSRSSSPGNKSKKTEN 116
Query: 140 RGQRQLK-------KQEKWKQEPSEDEQEQGTSA----ESEPEQKKVKARRPVPRRTVPK 188
R + + K K++K ++ EDE+E+ + E E +K K R R K
Sbjct: 117 RSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRK 176
Query: 189 PRV-------KKQPKTQRGKR-KKQDSSDEDDDDDEAPKRQTRRRAAK---NVSYKEDDD 237
+ K+ + ++GK+ +D D++DD EA K + +Y E+
Sbjct: 177 KAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVK 236
Query: 238 FETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFD 297
E ++ + G G +E++ + T+ KV+ KK + + N + ++
Sbjct: 237 EEVKKFNMRSVKGGGGNEKK-SGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYS 295
Query: 298 TEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSP 357
+E++E ++Q + + + L + G + E F+K L K+S
Sbjct: 296 SEEEEVDLQ--------TALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQ 347
Query: 358 EDVEYFNCQQE 368
E+V F + E
Sbjct: 348 EEVNVFRLEME 358
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 60.5 bits (145), Expect = 4e-09
Identities = 61/276 (22%), Positives = 116/276 (42%), Gaps = 43/276 (15%)
Query: 80 PEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKR 139
P+ KE+ +E + + K+ +E P + EP NI + S E K
Sbjct: 415 PKVKEEKKDLEESMEEALKLDQEMP-------LTEVKSEPEE-NIDSNSESEREEIELKS 466
Query: 140 -RGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRV--KKQPK 196
RG+R++ + ++ E+E+ + +++ E K V + + + K PK
Sbjct: 467 PRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPK 526
Query: 197 TQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQ 256
+ K KKQ+ SD+D D++E ++ +E+ + + DS EG +++
Sbjct: 527 QKEKKIKKQEDSDKDSDEEEEKSQE-----------REETESKCDS--------EGEEDE 567
Query: 257 QDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSY 316
+D + +++ K G + +Y TE D+GE+ YL+ + GW+
Sbjct: 568 EDMEPCL---TGTKVKVKYGRGKTQKIYEASIK-------STEIDDGEVLYLVHYYGWNV 617
Query: 317 IHSTWESEESLQQQKVKG---LKKLENFKKKEDEIK 349
+ W + + KG K+ + K KED K
Sbjct: 618 RYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEK 653
Score = 37.7 bits (86), Expect = 0.025
Identities = 43/220 (19%), Positives = 82/220 (37%), Gaps = 32/220 (14%)
Query: 38 ESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPA---SKKERIA 94
+ ++ SD S E + E +ES+ +SE E +P L K K K ++I
Sbjct: 533 KKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIY 592
Query: 95 DVKKMWEEYPD--------VYG--VRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQ 144
+ E D YG VR + + + + + G PK++ +++
Sbjct: 593 EASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPL--------DKGGPKKKQKKK 644
Query: 145 LKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKK 204
K +E +++ DE E++K K RP + T+ KT + K
Sbjct: 645 AKNKEDSEKDEKRDE-----------ERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS 693
Query: 205 QDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDD 244
S + + +D K + +++++ D D
Sbjct: 694 DSCSSDSETEDALEKNLINEELSLKDELEKNENLNDDKLD 733
>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
sapiens]
Length = 1203
Score = 60.5 bits (145), Expect = 4e-09
Identities = 61/276 (22%), Positives = 116/276 (42%), Gaps = 43/276 (15%)
Query: 80 PEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKR 139
P+ KE+ +E + + K+ +E P + EP NI + S E K
Sbjct: 415 PKVKEEKKDLEESMEEALKLDQEMP-------LTEVKSEPEE-NIDSNSESEREEIELKS 466
Query: 140 -RGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRV--KKQPK 196
RG+R++ + ++ E+E+ + +++ E K V + + + K PK
Sbjct: 467 PRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPK 526
Query: 197 TQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQ 256
+ K KKQ+ SD+D D++E ++ +E+ + + DS EG +++
Sbjct: 527 QKEKKIKKQEDSDKDSDEEEEKSQE-----------REETESKCDS--------EGEEDE 567
Query: 257 QDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSY 316
+D + +++ K G + +Y TE D+GE+ YL+ + GW+
Sbjct: 568 EDMEPCL---TGTKVKVKYGRGKTQKIYEASIK-------STEIDDGEVLYLVHYYGWNV 617
Query: 317 IHSTWESEESLQQQKVKG---LKKLENFKKKEDEIK 349
+ W + + KG K+ + K KED K
Sbjct: 618 RYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEK 653
Score = 37.7 bits (86), Expect = 0.025
Identities = 43/220 (19%), Positives = 82/220 (37%), Gaps = 32/220 (14%)
Query: 38 ESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPA---SKKERIA 94
+ ++ SD S E + E +ES+ +SE E +P L K K K ++I
Sbjct: 533 KKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIY 592
Query: 95 DVKKMWEEYPD--------VYG--VRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQ 144
+ E D YG VR + + + + + G PK++ +++
Sbjct: 593 EASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPL--------DKGGPKKKQKKK 644
Query: 145 LKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKK 204
K +E +++ DE E++K K RP + T+ KT + K
Sbjct: 645 AKNKEDSEKDEKRDE-----------ERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS 693
Query: 205 QDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDD 244
S + + +D K + +++++ D D
Sbjct: 694 DSCSSDSETEDALEKNLINEELSLKDELEKNENLNDDKLD 733
>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
sapiens]
Length = 1257
Score = 60.5 bits (145), Expect = 4e-09
Identities = 61/276 (22%), Positives = 116/276 (42%), Gaps = 43/276 (15%)
Query: 80 PEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKR 139
P+ KE+ +E + + K+ +E P + EP NI + S E K
Sbjct: 415 PKVKEEKKDLEESMEEALKLDQEMP-------LTEVKSEPEE-NIDSNSESEREEIELKS 466
Query: 140 -RGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRV--KKQPK 196
RG+R++ + ++ E+E+ + +++ E K V + + + K PK
Sbjct: 467 PRGRRRIARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPK 526
Query: 197 TQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQ 256
+ K KKQ+ SD+D D++E ++ +E+ + + DS EG +++
Sbjct: 527 QKEKKIKKQEDSDKDSDEEEEKSQE-----------REETESKCDS--------EGEEDE 567
Query: 257 QDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSY 316
+D + +++ K G + +Y TE D+GE+ YL+ + GW+
Sbjct: 568 EDMEPCL---TGTKVKVKYGRGKTQKIYEASIK-------STEIDDGEVLYLVHYYGWNV 617
Query: 317 IHSTWESEESLQQQKVKG---LKKLENFKKKEDEIK 349
+ W + + KG K+ + K KED K
Sbjct: 618 RYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEK 653
Score = 37.7 bits (86), Expect = 0.025
Identities = 43/220 (19%), Positives = 82/220 (37%), Gaps = 32/220 (14%)
Query: 38 ESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPA---SKKERIA 94
+ ++ SD S E + E +ES+ +SE E +P L K K K ++I
Sbjct: 533 KKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIY 592
Query: 95 DVKKMWEEYPD--------VYG--VRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQ 144
+ E D YG VR + + + + + G PK++ +++
Sbjct: 593 EASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPL--------DKGGPKKKQKKK 644
Query: 145 LKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKK 204
K +E +++ DE E++K K RP + T+ KT + K
Sbjct: 645 AKNKEDSEKDEKRDE-----------ERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS 693
Query: 205 QDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDD 244
S + + +D K + +++++ D D
Sbjct: 694 DSCSSDSETEDALEKNLINEELSLKDELEKNENLNDDKLD 733
>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
protein [Homo sapiens]
Length = 1463
Score = 59.3 bits (142), Expect = 8e-09
Identities = 49/230 (21%), Positives = 98/230 (42%), Gaps = 11/230 (4%)
Query: 5 KDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNS-SSESSESQ 63
K S++ + + S + + S + ++ +Q ++ H SE+N SS+ ++ +
Sbjct: 707 KHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEK 766
Query: 64 SESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFN 123
E+ S+ + S + + +KP +++ R W D + + Q PS
Sbjct: 767 VETVSQPSESPKDTI--DKTKKPRTRRSRFHSPSTTWSPNKD---TPQEKKRPQSPSPRR 821
Query: 124 IKEEASSGSESGSPKR---RGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
+ S S+S SPK RG+++ + Q K E Q Q S + + ++ ++
Sbjct: 822 ETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESL 881
Query: 181 VPRRTVPKPRVKKQPKTQRGK--RKKQDSSDEDDDDDEAPKRQTRRRAAK 228
PRR + + QP+ + K + S E + D + +R+ RR K
Sbjct: 882 SPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRK 931
Score = 50.4 bits (119), Expect = 4e-06
Identities = 55/265 (20%), Positives = 102/265 (38%), Gaps = 16/265 (6%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQ 63
N S D + + + + ++ ++ + P + ++ E Q
Sbjct: 756 NMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQ 815
Query: 64 SESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYP--DVYGVRRSNRSRQEPSR 121
S S G +S+ + P+ K E KK + P D+ RR ++SR P R
Sbjct: 816 SPSPRRETGKESRK-----SQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRS-PKR 869
Query: 122 FNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPV 181
+E S SES SP+R R+ K+ + ++ S E+ + S E E ++ + R
Sbjct: 870 DTTRE--SRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERER 927
Query: 182 PRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTR------RRAAKNVSYKED 235
R + R + ++ + K S D D +P+ + R R N Y+++
Sbjct: 928 RTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKN 987
Query: 236 DDFETDSDDLIEMTGEGVDEQQDNS 260
D + + + E +D NS
Sbjct: 988 DPEKQNENTRKEKNDIHLDADDPNS 1012
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 59.3 bits (142), Expect = 8e-09
Identities = 74/302 (24%), Positives = 114/302 (37%), Gaps = 70/302 (23%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQ 63
++D E+D S+ ++ E S +S S S SG S S S SES S
Sbjct: 389 SEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSS 448
Query: 64 SESESESAGSKSQPVLPEAKEKPASK-----------KERIADVKKMWEEYPDVYGVRRS 112
S+SE A SQ PE + P +K +++ + P G ++
Sbjct: 449 SDSE---ANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKE 505
Query: 113 NRSRQEPSRF----NIKEEASS-----------GSESGSPKRRGQRQL----------KK 147
R + + + KE +S+ GSESG +++ Q KK
Sbjct: 506 GREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKK 565
Query: 148 QEKWKQEPSEDEQEQGTSAESE---------PEQKKVKA----RRP--------VPRRTV 186
Q K ++ + +E G ESE P + A R+P PR T
Sbjct: 566 QPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTA 625
Query: 187 PKPRVKKQPKTQRGKRK--KQDSSDEDDDDDEA--PKRQT------RRRAAKNVSYKEDD 236
K + K K+ + R+ + D+S D D+ E+ P QT R K S +E+D
Sbjct: 626 EKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEED 685
Query: 237 DF 238
F
Sbjct: 686 SF 687
Score = 43.5 bits (101), Expect = 4e-04
Identities = 56/292 (19%), Positives = 102/292 (34%), Gaps = 36/292 (12%)
Query: 3 RNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSES 62
++ + E S + S S E +D+ S E S P S + S+ +
Sbjct: 618 KSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVK 677
Query: 63 QSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRF 122
S E E + + + P +KE ++ + + + YP + + + +R P +
Sbjct: 678 PSSVEEEDSFFRQRMF------SPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRI-PGKP 730
Query: 123 NIKEEASSGSESGSPKR---------------RGQRQLKKQE-----KWKQEPSEDEQEQ 162
+ E G + P++ +G+R+ K ++ + K+ +ED+
Sbjct: 731 YKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSA 790
Query: 163 GTSAESEPEQKKVKARR-----PVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEA 217
G S E K A + P P VP K PKT+ G RK+ S
Sbjct: 791 GHKPSSNRESSKQSAAKEKDLLPSPAGPVPS----KDPKTEHGSRKRTISQSSSLKSSSN 846
Query: 218 PKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDS 269
++T + + S + E + + E N LDS
Sbjct: 847 SNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDS 898
Score = 41.2 bits (95), Expect = 0.002
Identities = 81/395 (20%), Positives = 151/395 (38%), Gaps = 59/395 (14%)
Query: 7 KSQEEDSSLHSNASSHSASEEASGSDSGSQS-----ESEQGSDPGSG------HGSESNS 55
+SQ+ S L S HS+ ++GS SG+ S + E ++ GS HGSE +
Sbjct: 119 QSQKRSSGLQSG---HSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSK 175
Query: 56 SSESS--ESQSESESESAGSKSQPVLPEAKEKPASKKERIADV-------------KKMW 100
S SS + Q+ S S+ S+S +KE SK R D +
Sbjct: 176 SRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHST 235
Query: 101 EEYPDVYGVRRSNRSRQEPSRF--------NIKEEASSGSESGSPKRRGQRQLKKQEKWK 152
+ +P + +SN Q+P+ + +++ + SS S +LK K
Sbjct: 236 QSFPPSL-MSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAH 294
Query: 153 ----QEPSE--DEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQD 206
+ PS+ D G + + K++ P P + P K +P K+
Sbjct: 295 LTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTP-CKTEPSKFPFPTKESQ 353
Query: 207 SSDEDDDDDEA--PKRQTRRRAAKN-------VSYKEDDDFETDSDDLIEMT--GEGVDE 255
S+ + + P + + +K+ +S ED D E D D + + G +
Sbjct: 354 QSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEP 413
Query: 256 QQDNSETIEKVLD---SRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWK 312
NSE + D S G + ++G+ + + ++ + + + E E KW+
Sbjct: 414 SHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQ 473
Query: 313 GWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDE 347
++++ + S + + +KK+ E
Sbjct: 474 LDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGRE 508
Score = 31.2 bits (69), Expect = 2.3
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 11/83 (13%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQ 63
++ ++ + SSL S+++S+ +E SGS S S S+Q +E +SS S E +
Sbjct: 830 SRKRTISQSSSLKSSSNSN---KETSGSSKNSSSTSKQKK-------TEGKTSSSSKEVK 879
Query: 64 SESESESAGSK-SQPVLPEAKEK 85
++ S S+ S P L +K +
Sbjct: 880 EKAPSSSSNCPPSAPTLDSSKPR 902
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 58.9 bits (141), Expect = 1e-08
Identities = 56/327 (17%), Positives = 142/327 (43%), Gaps = 23/327 (7%)
Query: 61 ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
E ++ E E K + + E +EK ++ +K+WE+ QE
Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ---------EKMQEQEEK 454
Query: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEK----WKQEPSEDEQEQGTSAESEPEQKKVK 176
+ +E+ E +++ RQ K +E+ W+QE +QEQ + E ++ +
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
Query: 177 ARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDD 236
R R + ++ +Q + R ++K Q+ + D +E + + R R + +E++
Sbjct: 515 RLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR-EREKKMREEE 573
Query: 237 DFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDF 296
+ + ++ ++ E + EQ++ E+ + + K ++ E +
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK---------MWEQEEKMWEQEEE 624
Query: 297 DTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVS 356
D +++ E+ + + K WE EE +++Q+ K ++ E + +E+++++ K+
Sbjct: 625 DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Query: 357 PEDVEYFNCQQELASELNKQYQIVERV 383
++ + ++++ + K + E++
Sbjct: 685 GQEEKMREQEEKMRGQEEKMWGQEEKM 711
Score = 43.9 bits (102), Expect = 3e-04
Identities = 53/286 (18%), Positives = 120/286 (41%), Gaps = 23/286 (8%)
Query: 81 EAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRR 140
E +EK +++R+ + +K E ++ R ++E ++E+ E R
Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEE----QMQEQEEKMWEQEEKMRE 328
Query: 141 GQRQLKKQEK--WKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQ 198
+ ++ +QE+ W+QE EQEQ + E ++ + R R + ++ +Q +
Sbjct: 329 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKM 388
Query: 199 RGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQD 258
+ + + ++ + +++E + Q + + + E ++ E L E E + EQ+
Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK-EKLWEQEK 447
Query: 259 NSETIEKVLDSR---LGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWS 315
E EK+ + ++ G ++ E + ++++ Q + K W
Sbjct: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ---EQKMWD 504
Query: 316 YIHSTWESEESL--QQQKVKGLKKL--------ENFKKKEDEIKQW 351
WE +E L ++++++ KK+ E K +E E K W
Sbjct: 505 QEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
Score = 41.6 bits (96), Expect = 0.002
Identities = 61/339 (17%), Positives = 137/339 (40%), Gaps = 51/339 (15%)
Query: 68 SESAGSKSQPVLPEAKEKPASKKERIADVK------KMWEEYPDVYGVRRSNRSRQEP-- 119
+ES S+ Q + E K K K + V+ +MW + ++ + R ++E
Sbjct: 199 AESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMW 258
Query: 120 -SRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSE---------DEQEQGTSAESE 169
++E+ E RR +++L++QEK +E + +++EQ E +
Sbjct: 259 RQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEK 318
Query: 170 PEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKN 229
+++ K R + + R+ +Q K R + +K +E + + R+ R +
Sbjct: 319 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 378
Query: 230 VSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEAN 289
E ++ + + + E + +E++ E EK+
Sbjct: 379 EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM----------------------Q 416
Query: 290 GDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKED--- 346
++ E+ E + Q L + K WE +E +Q+Q+ K ++ E + +E+
Sbjct: 417 KQEENMWEQEEKEWQQQRLPEQK-----EKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWG 470
Query: 347 -EIKQW-LGKVSPEDVEYFNCQQELASELNKQYQIVERV 383
E K W K+ ++ + + ++++ + K + ER+
Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 509
Score = 39.7 bits (91), Expect = 0.006
Identities = 35/183 (19%), Positives = 68/183 (37%), Gaps = 12/183 (6%)
Query: 2 MRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSS-ESS 60
MR +++ +E + + EE E E+ E E
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 61 ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEP- 119
E E E E + + ++ E +EK ++E KMWE+ + R ++E
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE------KMWEQEEKMREQEEKMREQEEKM 669
Query: 120 ----SRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKV 175
+ +EE G E ++ + + ++++ W QE QE+ + E +K+
Sbjct: 670 QGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEE 729
Query: 176 KAR 178
+ R
Sbjct: 730 RIR 732
Score = 37.4 bits (85), Expect = 0.032
Identities = 39/211 (18%), Positives = 84/211 (39%), Gaps = 26/211 (12%)
Query: 2 MRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
MR + K +++ + + E+ + E E+ + E E E
Sbjct: 523 MREQKKMWQQEEKMREEKKTQE-QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 581
Query: 62 SQSESESESAGSKSQPVLPEAKEKPASKKERIADVK-KMWEEYPDVYGVRRSNRSRQEPS 120
E E + + + + E +EK ++E++ + + KMWE+ +E
Sbjct: 582 KMQEQEEKMREQEEK--MWEQEEKMQEQEEKMWEQEEKMWEQ--------------EEED 625
Query: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQ-KKVKARR 179
+ +EE E + Q ++++ W+QE EQE+ + E Q ++ K R
Sbjct: 626 KMQEQEEMMWEQEE-------KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRE 678
Query: 180 PVPRRTVPKPRVKKQPKTQRGKRKKQDSSDE 210
+ + ++++Q + RG+ +K +E
Sbjct: 679 QEEKMQGQEEKMREQEEKMRGQEEKMWGQEE 709
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 58.9 bits (141), Expect = 1e-08
Identities = 63/317 (19%), Positives = 134/317 (42%), Gaps = 24/317 (7%)
Query: 8 SQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSS--------SES 59
++EE+ S A S+ EE D +Q E + G+ ++ ++
Sbjct: 127 AKEENPRRASKAVEESSDEERQ-RDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKA 185
Query: 60 SESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEP 119
S S+ ++ ES S+++PV AK+ +K + +K+ +E + ++ + +E
Sbjct: 186 SVSRKQAREESEESEAEPVQRTAKKVEGNKGTK--SLKESEQESEEEILAQKKEQREEEV 243
Query: 120 SRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARR 179
+E+ G + G+R+ ++E+ ++ S+ ++ G S E +++ +
Sbjct: 244 EEEEKEEDEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGD 303
Query: 180 PVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDD---EAPKRQTRRRAAKNVSYKEDD 236
R P + K + +TQ K+ S ED++D E + +R+ A + E+
Sbjct: 304 DSGRDREPPVQRKSEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTSGEES 363
Query: 237 DFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGAT--GASTTVYAIEANGDPSG 294
D E + D G G ++ N + + +KG T +S++ + EA G +G
Sbjct: 364 DLEREVSD--SEAGGGPQGERKNRSS------KKSSRKGRTRSSSSSSDGSPEAKGGKAG 415
Query: 295 DFDTEKDEGEIQYLIKW 311
+D + L ++
Sbjct: 416 SGRRGEDHPAVMRLKRY 432
Score = 52.0 bits (123), Expect = 1e-06
Identities = 55/238 (23%), Positives = 106/238 (44%), Gaps = 39/238 (16%)
Query: 57 SESSESQSESESESAGSK--SQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNR 114
+ S S E E + A + + +L ++ AS+++++ D+ K + P +
Sbjct: 35 AHSGRSHLEPEEKQALKRLVEEELLKMQVDEAASREDKL-DLTKKGKRPP-------TPC 86
Query: 115 SRQEPSRFNIKEEASSGSESGSPKRRG---------------QRQLKKQEKWKQEPSEDE 159
S E RF E+ SGSE+ SP G + ++ K +E S++E
Sbjct: 87 SDPERKRFRFNSESESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEESSDEE 146
Query: 160 QEQGTSAE-----SEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDD 214
+++ A+ SE E+K K +T KP VKKQ + +KQ + +E ++
Sbjct: 147 RQRDLPAQRGEESSEEEEKGYKG------KTRKKPVVKKQAPGKASVSRKQ-AREESEES 199
Query: 215 DEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLG 272
+ P ++T ++ N K + E +S++ E+ + +++++ E EK D G
Sbjct: 200 EAEPVQRTAKKVEGNKGTKSLKESEQESEE--EILAQKKEQREEEVEEEEKEEDEEKG 255
Score = 31.2 bits (69), Expect = 2.3
Identities = 66/317 (20%), Positives = 122/317 (38%), Gaps = 35/317 (11%)
Query: 141 GQRQLKKQEKWKQEPSEDEQ------EQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQ 194
G+ L+ +EK + +E+ ++ S E + + K K +RP P P +
Sbjct: 38 GRSHLEPEEKQALKRLVEEELLKMQVDEAASREDKLDLTK-KGKRP------PTPCSDPE 90
Query: 195 PKTQRGKRKKQDSSDEDDDDDEAP-------------KRQTRRRAAKNVSYKEDDDFETD 241
K R + + S+ D P K + RRA+K V D++ + D
Sbjct: 91 RKRFRFNSESESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEESSDEERQRD 150
Query: 242 SDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKD 301
L GE E+++ K + KK A G ++ + + + S + + E
Sbjct: 151 ---LPAQRGEESSEEEEKGYK-GKTRKKPVVKKQAPGKASV--SRKQAREESEESEAEPV 204
Query: 302 EGEIQYLIKWKGWSYI-HSTWESEES-LQQQKVKGLKKLENFKKKEDEIK-QWLGKVSPE 358
+ + + KG + S ESEE L Q+K + +++E +K+EDE K W +
Sbjct: 205 QRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSN 264
Query: 359 DVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWM 418
++ + ++ +++ + + K D R+P + E +
Sbjct: 265 GRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLK 324
Query: 419 GLPYSECSWEDEALIGK 435
G S EDE GK
Sbjct: 325 GGKRLSGSSEDEEDSGK 341
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 58.9 bits (141), Expect = 1e-08
Identities = 86/410 (20%), Positives = 155/410 (37%), Gaps = 93/410 (22%)
Query: 10 EEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESE 69
+ + S+H+++SS S+S +S S S S S S S S+SSS SS S S S S
Sbjct: 141 DPNRSIHTSSSSSSSSSSSSSSSSSSSSSSS----------SSSSSSSSSSSSSSSSSSS 190
Query: 70 SAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEAS 129
++ SK ++ E KEKP S SR+ S F
Sbjct: 191 TSFSKPHKLMKEHKEKP-------------------------SKDSREHKSAF------- 218
Query: 130 SGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEP-EQKKVKARRPVPRRTVPK 188
+EPS D + + +P E K +K + VP+ +
Sbjct: 219 -----------------------KEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKE 255
Query: 189 PR-VKKQPKTQ-------RGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET 240
P+ + K+PK G+ KK S D E + R++++ +K F +
Sbjct: 256 PKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFK---SFSS 312
Query: 241 DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK 300
++ + D++Q ++ K+ ++ + + +T+ + DP+ D D E+
Sbjct: 313 APPLILTCS---ADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPN-DSDVEE 368
Query: 301 D---EGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSP 357
+ + + + S S++ ++ QQ ++ + K + E+E
Sbjct: 369 NISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEE---------S 419
Query: 358 EDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAP 407
++VE + E+ +N+ RV S S P H P P
Sbjct: 420 DEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPP 469
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 58.9 bits (141), Expect = 1e-08
Identities = 54/247 (21%), Positives = 103/247 (41%), Gaps = 25/247 (10%)
Query: 4 NKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGH--GSESNSSSESSE 61
NK+K + + + + + + + S S + S + S P G S+SNSSS SS+
Sbjct: 109 NKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSD 168
Query: 62 SQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSR 121
S S SE E E +E A +++M E+ + R + R
Sbjct: 169 SDSSSEDEEFHD-------GYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRR 221
Query: 122 FNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKK------- 174
F IK++ + + +++ +++ +++E+ K++ ++ ++ Q TS E K+
Sbjct: 222 FEIKKKLKTAKKK---EKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKK 278
Query: 175 ------VKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAK 228
+KA R + + KKQP + +EDD E R +R ++
Sbjct: 279 SQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSD 338
Query: 229 NVSYKED 235
KE+
Sbjct: 339 EEEEKEE 345
Score = 40.8 bits (94), Expect = 0.003
Identities = 78/379 (20%), Positives = 150/379 (39%), Gaps = 35/379 (9%)
Query: 130 SGSESGSPK--RRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVP 187
+G + GSP RRG R +K K D + + ++ +Q+ + + +R
Sbjct: 22 AGGQEGSPGGGRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLS----LAKRKRS 77
Query: 188 KPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIE 247
K+ P +Q ++SD DD+ + ++ A+ + K + ++
Sbjct: 78 DSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKK--GTMKKQANKTAS 135
Query: 248 MTGEGVDEQQDNSETIE-KVLDSRLGKKGATGASTTVYAIEANGDPSGD--FDTEKDEGE 304
D ++S E +V DS ++ S + E D G+ E+D
Sbjct: 136 SGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRAR 195
Query: 305 IQYLIKWKGWSYIHSTWESEESLQQQ-KVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYF 363
++ + + + + + E E L+++ ++K KKL+ KKKE + K+ + E +
Sbjct: 196 LEQMTEKEREQELFNRIEKREVLKRRFEIK--KKLKTAKKKEKKEKKKKQEEEQEKKKLT 253
Query: 364 NCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYS 423
Q+ + NK+ + K K + + A R+ + E L K L S
Sbjct: 254 QIQESQVTSHNKERRSKR---DEKLDKKSQAMEELKA-EREKRKNRTAELLAKKQPLKTS 309
Query: 424 ECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE--N 481
E +DE ++ ++ S S +S+T + E + ++ P K QP L E
Sbjct: 310 EVYSDDE----EEEEDDKSSEKSDRSSRTSSSDEEEEKEEIPP----KSQPVSLPEELNR 361
Query: 482 LELRDYQLEGLNWLAHSWC 500
+ L ++LE WC
Sbjct: 362 VRLSRHKLE-------RWC 373
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 57.8 bits (138), Expect = 2e-08
Identities = 59/269 (21%), Positives = 119/269 (44%), Gaps = 17/269 (6%)
Query: 10 EEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESE 69
E +SL+ AS+ AS E S + + ++ + S P + ++ +SE + +S ++
Sbjct: 206 ETITSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTAD 265
Query: 70 SAGS--KSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEE 127
S G ++ P E + P +E +K +E+ ++ + N+ Q+ S +
Sbjct: 266 SGGEGLETAPKSEEFSDLPCPVEE----IKNYTKEHNNLILL---NKDVQQESSEQKNKS 318
Query: 128 ASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVP 187
G + +G+R+ +K+EK +++ ++ + T + +Q K K V +P
Sbjct: 319 TDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEK---EVESLKLP 375
Query: 188 KPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNV-SYKEDDDFETDSDDLI 246
+ + KT G K+D S D D D ++ S++ED + E + D +
Sbjct: 376 SEKNSNKAKTVEG--TKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSM 433
Query: 247 EMTGEGVDEQQDN--SETIEKVLDSRLGK 273
E D+++ N ++T + DS GK
Sbjct: 434 EEGEITSDDEEKNKQNKTKTQTSDSSEGK 462
Score = 40.0 bits (92), Expect = 0.005
Identities = 64/294 (21%), Positives = 113/294 (38%), Gaps = 61/294 (20%)
Query: 5 KDKSQEEDSSLHSNASSHSASEEASGSDS----GSQSESEQGSDPGSGHGSESNSSSESS 60
K+ +EE H S E D+ S+ E+ Q P + +S
Sbjct: 2759 KEVEEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDL 2818
Query: 61 ESQSESESESAGSKSQPVLPEAKEKPASK------KERIADVKKMWEEYPDVYGVRRSNR 114
E ++ SE+ + S+ V+ E E +S+ ++ D K EE + R+ R
Sbjct: 2819 EELPKTSSETNSTTSR-VMEEKDEYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGR 2877
Query: 115 SRQEPSRFNIKEEASSGSESG------SPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAES 168
R+ P +K + S +++G SP + ++ E K+ + + QE+ S +
Sbjct: 2878 PRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKE--TANLQERSISNDD 2935
Query: 169 EPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAK 228
E+ RR RG++ K+ + DD + P+R+ + K
Sbjct: 2936 GEEKIVTSVRR-------------------RGRKPKRSLTVSDDAESSEPERKRQ----K 2972
Query: 229 NVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTT 282
+VS +D E +SD+ E +E++D GAT STT
Sbjct: 2973 SVSDPVEDKKEQESDE------EEEEEEEDE-------------PSGATTRSTT 3007
Score = 39.7 bits (91), Expect = 0.006
Identities = 70/382 (18%), Positives = 148/382 (38%), Gaps = 55/382 (14%)
Query: 13 SSLHSNASS---HSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQ------ 63
SS+H++ S EE SDS + E + + +S+SSE +
Sbjct: 409 SSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRH 468
Query: 64 -------------SESESE-SAGSKSQPVLPEAKEKPASK---KERIADVKKMWEE---Y 103
S+S+ E + + Q + E +E+ + +E++ + +K E
Sbjct: 469 AYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKS 528
Query: 104 PDVYGVRRSNRSRQEPSRFNIKEEASSGSE-------------SGSPKRRGQRQLKKQEK 150
G RS+ +E S +++ +A+ E +++ R +++ K
Sbjct: 529 SKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSK 588
Query: 151 WKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDE 210
KQ+ ED +E ++E E++K+ + + + K +P ++ +R +
Sbjct: 589 KKQQYEEDSKETLKTSE-HCEKEKISSSKELKH-----VHAKSEP-SKPARRLSESLHVV 641
Query: 211 DDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDL---IEMTGEGVDEQQDNSETIEKVL 267
D++ +E+ + +R E ETD+ D+ +E + +E Q T++
Sbjct: 642 DENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEK 701
Query: 268 DSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESL 327
+ + + + + + E ++ K+KG +H T +E+
Sbjct: 702 HLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKG-DCMHKT--GDETE 758
Query: 328 QQQKVKGLKKLENFKKKEDEIK 349
KGLK EN +K+ + K
Sbjct: 759 LHSSEKGLKVEENIQKQSQQTK 780
Score = 38.5 bits (88), Expect = 0.014
Identities = 44/248 (17%), Positives = 97/248 (39%), Gaps = 27/248 (10%)
Query: 56 SSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRS 115
S E+ ++ E E S + AK +P+ R+++ + +E N++
Sbjct: 597 SKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDE----------NKN 646
Query: 116 RQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKV 175
+ R + + ++ G + R +K+Q + + +E+ Q+Q ++ ++E KK
Sbjct: 647 ESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKD 706
Query: 176 KARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKED 235
+ P + + K + K +R K +D K + + + +K
Sbjct: 707 DSETPHLKSLLKKEVKSSKEKPEREKTPSED------------KLSVKHKYKGDCMHKTG 754
Query: 236 DDFETDSDDLIEMTGEGVDEQ-QDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSG 294
D+ E S + G V+E Q S+ + D + +K + + +G P
Sbjct: 755 DETELHSSE----KGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVS 810
Query: 295 DFDTEKDE 302
++ + DE
Sbjct: 811 EYIIKTDE 818
Score = 33.9 bits (76), Expect = 0.35
Identities = 46/247 (18%), Positives = 94/247 (38%), Gaps = 38/247 (15%)
Query: 10 EEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESE-- 67
+E++S ++SE S + + + E S +G E N ++ +SQ E +
Sbjct: 2811 KEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDD-DTIKSQEEDQPI 2869
Query: 68 ------------------SESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGV 109
SK+ + ++ P+S K ++ + +E ++
Sbjct: 2870 IIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKETANLQER 2929
Query: 110 RRSNRSRQEPSRFNIKEEA---------SSGSESGSPKRRGQRQLKK--QEKWKQEPSED 158
SN +E +++ S +ES P+R+ Q+ + ++K +QE E+
Sbjct: 2930 SISNDDGEEKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEE 2989
Query: 159 EQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVK-KQPKTQRGKRKKQDSSDEDDDDDEA 217
E+E+ S + +T P +K K+ + G R + E EA
Sbjct: 2990 EEEEEEDEPSGATTRSTTRSEAQRSKTQLSPSIKRKREVSPPGARTRGQQRVE-----EA 3044
Query: 218 PKRQTRR 224
P ++ +R
Sbjct: 3045 PVKKAKR 3051
Score = 32.0 bits (71), Expect = 1.3
Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 8/64 (12%)
Query: 8 SQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESE 67
SQE D S++ SA S +E G P S GSE +S + S+SE
Sbjct: 1774 SQEGDGSVNDGTEGESAVT--------STGITEDGEGPASCTGSEDSSEGFAISSESEEN 1825
Query: 68 SESA 71
ESA
Sbjct: 1826 GESA 1829
Score = 31.6 bits (70), Expect = 1.8
Identities = 70/317 (22%), Positives = 116/317 (36%), Gaps = 63/317 (19%)
Query: 10 EEDSSLHSNAS---SHSASEEASGSDSGSQSESEQGSDPGSGHGSESN----SSSESSES 62
E+D ++ ++ S + AS E +G D+ ++ + D SE N + ES +
Sbjct: 2600 EQDLTIKNDYSGKWTDQASAEKTGDDNSTRKSFPEEGDIMVTVSSEENVCDIGNEESPLN 2659
Query: 63 QSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRS------- 115
A K + +P +EK E +A + + P G+ R
Sbjct: 2660 VLGGLKLKANLKMEAYVPSEEEKNG---EILAPPESLCGGKPS--GIAELQREPLLVNES 2714
Query: 116 -RQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKK 174
E S F EE S S + G++ E G S E++P++ +
Sbjct: 2715 LNVENSGFRTNEEIHSESYNKGEISSGRKD------------NAEAISGHSVEADPKEVE 2762
Query: 175 VKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKE 234
+ R +P+R KRK+ S ED+ DD +R A+ +
Sbjct: 2763 EEERH-MPKR----------------KRKQHYLSSEDEPDDNPDVLDSRIETAQRQCPET 2805
Query: 235 D--DDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDP 292
+ D E +S DL E+ + S +E+ K + + TT E N D
Sbjct: 2806 EPHDTKEENSRDLEELPKTSSETNSTTSRVMEE-------KDEYSSSETTGEKPEQNDD- 2857
Query: 293 SGDFDTEKDEGEIQYLI 309
DT K + E Q +I
Sbjct: 2858 ----DTIKSQEEDQPII 2870
Score = 31.2 bits (69), Expect = 2.3
Identities = 51/273 (18%), Positives = 105/273 (38%), Gaps = 29/273 (10%)
Query: 52 ESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRR 111
+S +E + +SE+ S + + +KEKP +K D + +Y +
Sbjct: 694 KSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKT 753
Query: 112 SNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPE 171
+ + S +K E + +S K + +++ K + E + SE
Sbjct: 754 GDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSE-- 811
Query: 172 QKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVS 231
+K V + K R KT+ + ++ S + D K+ ++ S
Sbjct: 812 -YIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSES 870
Query: 232 YKEDD-DFETDSDDLIEMTGEGVDEQQDNSETI-----------------EKVLDSRLGK 273
Y ED D ++ + D E V +++ ++++ KV+++ L +
Sbjct: 871 YSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETEL-Q 929
Query: 274 KGATGASTTVYAIEANGDPSGDFDTEKDEGEIQ 306
+GAT +TT P + +TE+++ E Q
Sbjct: 930 EGATKQATT-------PKPDKEKNTEENDSEKQ 955
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.122 0.344
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,526,866
Number of Sequences: 37866
Number of extensions: 1135186
Number of successful extensions: 18277
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 543
Number of HSP's successfully gapped in prelim test: 1076
Number of HSP's that attempted gapping in prelim test: 8754
Number of HSP's gapped (non-prelim): 6300
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.