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Search of human proteins with 110578649
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110578649 cache domain containing 1 [Homo sapiens]
(1223 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110578649 cache domain containing 1 [Homo sapiens] 2490 0.0
gi|54112394 calcium channel, voltage-dependent, alpha 2/delta su... 103 1e-21
gi|54112392 calcium channel, voltage-dependent, alpha 2/delta su... 103 1e-21
gi|54112390 calcium channel, voltage-dependent, alpha 2/delta su... 98 5e-20
gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3 ... 91 5e-18
gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subun... 83 1e-15
gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor ... 45 3e-04
gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor... 45 3e-04
gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor... 45 3e-04
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [... 38 0.052
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens] 38 0.068
gi|4826988 ribosomal protein L3-like [Homo sapiens] 37 0.15
gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens] 35 0.34
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula... 35 0.44
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula... 35 0.44
gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens] 34 0.97
gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens] 34 0.97
gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens] 34 0.97
gi|119220564 one cut domain, family member 2 [Homo sapiens] 34 0.97
gi|216548385 dachsous 2 isoform 2 [Homo sapiens] 32 2.8
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 32 3.7
gi|194733735 transient receptor potential cation channel, subfam... 32 3.7
gi|4507687 transient receptor potential cation channel, subfamil... 32 3.7
gi|4505243 myelin protein zero [Homo sapiens] 32 3.7
gi|166295173 kin of IRRE like [Homo sapiens] 32 3.7
gi|110578665 seven in absentia homolog 3 [Homo sapiens] 32 3.7
gi|55770830 chromobox homolog 4 [Homo sapiens] 32 4.8
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 32 4.8
gi|208431827 eukaryotic translation initiation factor 2-alpha ki... 31 6.3
gi|4506103 eukaryotic translation initiation factor 2-alpha kina... 31 6.3
>gi|110578649 cache domain containing 1 [Homo sapiens]
Length = 1223
Score = 2490 bits (6453), Expect = 0.0
Identities = 1223/1223 (100%), Positives = 1223/1223 (100%)
Query: 1 MRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVE 60
MRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVE
Sbjct: 1 MRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVE 60
Query: 61 ASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLN 120
ASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLN
Sbjct: 61 ASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLN 120
Query: 121 SVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVV 180
SVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVV
Sbjct: 121 SVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVV 180
Query: 181 ILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATS 240
ILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATS
Sbjct: 181 ILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATS 240
Query: 241 ETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSK 300
ETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSK
Sbjct: 241 ETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSK 300
Query: 301 DSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVP 360
DSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVP
Sbjct: 301 DSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVP 360
Query: 361 DRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSK 420
DRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSK
Sbjct: 361 DRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSK 420
Query: 421 PCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEP 480
PCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEP
Sbjct: 421 PCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEP 480
Query: 481 PLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYA 540
PLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYA
Sbjct: 481 PLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYA 540
Query: 541 WKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLE 600
WKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLE
Sbjct: 541 WKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLE 600
Query: 601 SPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHV 660
SPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHV
Sbjct: 601 SPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHV 660
Query: 661 TDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLIS 720
TDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLIS
Sbjct: 661 TDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLIS 720
Query: 721 LTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQD 780
LTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQD
Sbjct: 721 LTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQD 780
Query: 781 GGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCN 840
GGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCN
Sbjct: 781 GGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCN 840
Query: 841 SFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCAC 900
SFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCAC
Sbjct: 841 SFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCAC 900
Query: 901 SMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPG 960
SMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPG
Sbjct: 901 SMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPG 960
Query: 961 LQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLDKPYCAPQKECFGGIVGAK 1020
LQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLDKPYCAPQKECFGGIVGAK
Sbjct: 961 LQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLDKPYCAPQKECFGGIVGAK 1020
Query: 1021 SPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSP 1080
SPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSP
Sbjct: 1021 SPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSP 1080
Query: 1081 LAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGT 1140
LAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGT
Sbjct: 1081 LAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGT 1140
Query: 1141 ESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRSH 1200
ESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRSH
Sbjct: 1141 ESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRSH 1200
Query: 1201 HPTLHHSHHLQAAVTVHTVDAEC 1223
HPTLHHSHHLQAAVTVHTVDAEC
Sbjct: 1201 HPTLHHSHHLQAAVTVHTVDAEC 1223
>gi|54112394 calcium channel, voltage-dependent, alpha 2/delta
subunit 2 isoform b [Homo sapiens]
Length = 1143
Score = 103 bits (256), Expect = 1e-21
Identities = 147/665 (22%), Positives = 276/665 (41%), Gaps = 98/665 (14%)
Query: 88 DGNFNTNVSRTISCDRLST------TVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSE 141
D NF V+ + + ++ T TV N L +V +N + +P + WQ F S
Sbjct: 194 DPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLWQVFGSA 253
Query: 142 EGIFTVFPAHKFRCKGS---YEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKD 198
G+ +PA +R Y+ R RP Y+ K +V+I+D SV+ L++ K
Sbjct: 254 TGVTRYYPATPWRAPKKIDLYDVRRRPWYIQGAS-SPKDMVIIVDVSGSVSGLTLKLMKT 312
Query: 199 AAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDS 258
+ +L + + D ++V + + + S C+ T L A K+ V + + +
Sbjct: 313 SVCEMLDTLSDDDYVNVASFNEKAQPVS---CF-THLVQANVRNKKVFKEAVQGMVAKGT 368
Query: 259 PTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKATLQVINEEN 318
T + GF+ AF ++++N +AN + +I+ + G ED+ +Q + E+
Sbjct: 369 -TGYKAGFEYAFDQLQNSNIT---RANCNKMIMMFTDG-------GEDR---VQDVFEKY 414
Query: 319 SFLNNSVMILTYAL--MNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSMMVLN 376
++ N +V + T+++ N VT L+ +A N G Y +P I G++ +
Sbjct: 415 NWPNRTVRVFTFSVGQHNYDVTPLQWMACA------NKGYY-----FEIPSI-GAIRINT 462
Query: 377 QLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYF----------GN 426
Q +GR L + + ++ + D +G GL++T + P +
Sbjct: 463 Q--EYLDVLGRPMV-LAGKEAKQVQWTNVYEDALGLGLVVTGTLPVFNLTQDGPGEKKNQ 519
Query: 427 LLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDI 486
L+LG++G+DV L I Y Y F ID GY L+HP+L P+ D
Sbjct: 520 LILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTNFREPVTLDF 579
Query: 487 IHYE-NIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQ 545
+ E E +R++++ G + I V S +I+++ +Y W ++
Sbjct: 580 LDAELEDENKEEIRRSMIDGNKGHKQIRTLVKSLDERYIDEVTR--------NYTWVPIR 631
Query: 546 DTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIM 605
T++ L +V +P Y + +L Q +F+ L P+
Sbjct: 632 STNYSLGLV----------------LPPYSTFYLQANLSDQILQVKYFEFLL----PSSF 671
Query: 606 LSAGS-FSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEW 664
S G F +P E+ ++ T +L + L+ N + + + D
Sbjct: 672 ESEGHVFIAPREYCKDLNAS---DNNTEFLKNFIELMEKVTPDSKQCNNFLLHNLILDTG 728
Query: 665 MTQMEM------SSLNTY-IVRRYIATPNGVLRIYPGSLMD---KAFDPTRRQWYLHAVA 714
+TQ + LNTY ++ + AT G+ R++P + + +P +Y ++
Sbjct: 729 ITQQLVERVWRDQDLNTYSLLAVFAATDGGITRVFPNKAAEDWTENPEPFNASFYRRSLD 788
Query: 715 NPGLI 719
N G +
Sbjct: 789 NHGYV 793
>gi|54112392 calcium channel, voltage-dependent, alpha 2/delta
subunit 2 isoform a [Homo sapiens]
Length = 1145
Score = 103 bits (256), Expect = 1e-21
Identities = 147/665 (22%), Positives = 276/665 (41%), Gaps = 98/665 (14%)
Query: 88 DGNFNTNVSRTISCDRLST------TVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSE 141
D NF V+ + + ++ T TV N L +V +N + +P + WQ F S
Sbjct: 194 DPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLWQVFGSA 253
Query: 142 EGIFTVFPAHKFRCKGS---YEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKD 198
G+ +PA +R Y+ R RP Y+ K +V+I+D SV+ L++ K
Sbjct: 254 TGVTRYYPATPWRAPKKIDLYDVRRRPWYIQGAS-SPKDMVIIVDVSGSVSGLTLKLMKT 312
Query: 199 AAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDS 258
+ +L + + D ++V + + + S C+ T L A K+ V + + +
Sbjct: 313 SVCEMLDTLSDDDYVNVASFNEKAQPVS---CF-THLVQANVRNKKVFKEAVQGMVAKGT 368
Query: 259 PTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKATLQVINEEN 318
T + GF+ AF ++++N +AN + +I+ + G ED+ +Q + E+
Sbjct: 369 -TGYKAGFEYAFDQLQNSNIT---RANCNKMIMMFTDG-------GEDR---VQDVFEKY 414
Query: 319 SFLNNSVMILTYAL--MNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSMMVLN 376
++ N +V + T+++ N VT L+ +A N G Y +P I G++ +
Sbjct: 415 NWPNRTVRVFTFSVGQHNYDVTPLQWMACA------NKGYY-----FEIPSI-GAIRINT 462
Query: 377 QLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYF----------GN 426
Q +GR L + + ++ + D +G GL++T + P +
Sbjct: 463 Q--EYLDVLGRPMV-LAGKEAKQVQWTNVYEDALGLGLVVTGTLPVFNLTQDGPGEKKNQ 519
Query: 427 LLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDI 486
L+LG++G+DV L I Y Y F ID GY L+HP+L P+ D
Sbjct: 520 LILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTNFREPVTLDF 579
Query: 487 IHYE-NIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQ 545
+ E E +R++++ G + I V S +I+++ +Y W ++
Sbjct: 580 LDAELEDENKEEIRRSMIDGNKGHKQIRTLVKSLDERYIDEVTR--------NYTWVPIR 631
Query: 546 DTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIM 605
T++ L +V +P Y + +L Q +F+ L P+
Sbjct: 632 STNYSLGLV----------------LPPYSTFYLQANLSDQILQVKYFEFLL----PSSF 671
Query: 606 LSAGS-FSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEW 664
S G F +P E+ ++ T +L + L+ N + + + D
Sbjct: 672 ESEGHVFIAPREYCKDLNAS---DNNTEFLKNFIELMEKVTPDSKQCNNFLLHNLILDTG 728
Query: 665 MTQMEM------SSLNTY-IVRRYIATPNGVLRIYPGSLMD---KAFDPTRRQWYLHAVA 714
+TQ + LNTY ++ + AT G+ R++P + + +P +Y ++
Sbjct: 729 ITQQLVERVWRDQDLNTYSLLAVFAATDGGITRVFPNKAAEDWTENPEPFNASFYRRSLD 788
Query: 715 NPGLI 719
N G +
Sbjct: 789 NHGYV 793
>gi|54112390 calcium channel, voltage-dependent, alpha 2/delta
subunit 1 [Homo sapiens]
Length = 1091
Score = 97.8 bits (242), Expect = 5e-20
Identities = 159/767 (20%), Positives = 310/767 (40%), Gaps = 112/767 (14%)
Query: 80 IPPSMMEFDGNFNTNVSRTISCDRLST------TVNSRAFNPGRDLNSVLADNLKSNPGI 133
I P +E D NF +S + + T T+ N L+ V N + +P +
Sbjct: 145 IKPVFIE-DANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNREEDPSL 203
Query: 134 KWQYFSSEEGIFTVFPAHKFRCKGS-------YEHRSRPIYVSTVRPQSKHIVVILDHGA 186
WQ F S G+ +PA + Y+ R RP Y+ K +++++D
Sbjct: 204 LWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAA-SPKDMLILVDVSG 262
Query: 187 SVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKM 246
SV+ L++ + + +L + + D ++V + + S C++ L A K+ +
Sbjct: 263 SVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVS---CFQ-HLVQANVRNKKVL 318
Query: 247 STFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEED 306
V+++ ++ T + GF AF+ + + N + +AN + +I+ + D EE
Sbjct: 319 KDAVNNI-TAKGITDYKKGFSFAFEQLLNYNVS---RANCNKIIMLFT------DGGEER 368
Query: 307 KKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALP 366
+ ++ N+ N + V + T+++ + ++ +A +N G Y +P
Sbjct: 369 AQ---EIFNKYNK--DKKVRVFTFSVGQHNY----DRGPIQWMACENKGYY-----YEIP 414
Query: 367 VIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCY--- 423
I G++ + Q +GR L + ++ + D + GL++T + P +
Sbjct: 415 SI-GAIRINTQ--EYLDVLGRPMV-LAGDKAKQVQWTNVYLDALELGLVITGTLPVFNIT 470
Query: 424 --FGN-------LLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRP 474
F N L+LG++GVDV+L I + Y F ID GY L+HP+L
Sbjct: 471 GQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPK 530
Query: 475 YLLSEPPLHTDII--HYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGK 532
S+ P+ D + EN K E +R ++ G + V S +I+K
Sbjct: 531 NPKSQEPVTLDFLDAELENDIKVE-IRNKMIDGESGEKTFRTLVKSQDERYIDK------ 583
Query: 533 EAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLH 592
N +Y W V T + L +V+ + K T+ ++ ++
Sbjct: 584 --GNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARSKKGKM----------- 630
Query: 593 FKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLI-----ANPGLK 647
K TL+ S +F +P ++ + ++ ++ T +L + I NP
Sbjct: 631 -KDSETLKPDNFEESGYTFIAPRDYCND---LKISDNNTEFLLNFNEFIDRKTPNNPSCN 686
Query: 648 FSVRNEVMATSHVTDE-----WMTQMEMSSLNTYIVRRYIATPNGVLRIYP---GSLMDK 699
+ N V+ + T+E W Q + + R++ T G+ R+YP G +
Sbjct: 687 ADLINRVLLDAGFTNELVQNYWSKQKNIKGVKA----RFVVTDGGITRVYPKEAGENWQE 742
Query: 700 AFDPTRRQWYLHAVANPGLISLTGPYLDVGG-----AGYVVTISHTIHSSSTQLSSGHTV 754
+ +Y ++ N + T PY + G +G +V+ + I+ L
Sbjct: 743 NPETYEDSFYKRSLDNDNYV-FTAPYFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVG 801
Query: 755 AVMGIDFTLRYFYKVLMD---LLPVCN-QDGGNKIRCFIMEDRGYLV 797
+ ++ + F K + PVC+ + + + C I++D G+L+
Sbjct: 802 IKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLL 848
>gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
subunit [Homo sapiens]
Length = 1091
Score = 91.3 bits (225), Expect = 5e-18
Identities = 113/521 (21%), Positives = 209/521 (40%), Gaps = 76/521 (14%)
Query: 1 MRRLAAEELGVVTMQRIFNSF---VYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQ 57
++ +AA+ G +Q+ + + V E+I +G V++LAK + E F++ + V R
Sbjct: 53 IKSIAAKYSGSQLLQKKYKEYEKDVAIEEI-DGLQLVKKLAKNMEEMFHKKSEAVRR--- 108
Query: 58 VVEASYTAHLTSPLTA---IQDCCTIPPSMMEFDGNFN--------------TNVSRTIS 100
+VEA+ AHL A + + + + DGNF N+ IS
Sbjct: 109 LVEAAEEAHLKHEFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNIS 168
Query: 101 CDRLSTTVNSRAFNPG--------RDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHK 152
+ N +P LN V DN +P + WQYF S +G F +P K
Sbjct: 169 LSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIK 228
Query: 153 FRCKGS----YEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAID 208
+ + ++ R+R Y+ K +V+++D S+ +L IAK IL +
Sbjct: 229 WEPDENGVIAFDCRNRKWYIQAAT-SPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLG 287
Query: 209 EHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQK 268
+ D +++ + + ++ C L A K + + + + +
Sbjct: 288 DDDFFNIIAYNEELHY--VEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLD-IALNE 344
Query: 269 AFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDS-----SEEDKKATL--QVINEENSFL 321
AF ++ N+ + + +++ + + D+ + D+K + +I E +F
Sbjct: 345 AFNILSDFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFA 404
Query: 322 NNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSMMVLNQLSNL 381
+N + A N G +++ L D+ E V R V++Q ++
Sbjct: 405 DN---LKWMACANKGF--FTQISTLADVQENVMEYLHVLSRPK---------VIDQEHDV 450
Query: 382 ETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGN-------LLLGIVGV 434
T + LP +D+ G L+ TV+ P + +LLG+VG
Sbjct: 451 VWTEAYIDSTLPQAQ--------KLTDDQGPVLMTTVAMPVFSKQNETRSKGILLGVVGT 502
Query: 435 DVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPY 475
DV + +L+ + Y+ + Y F I + GY L HP L Y
Sbjct: 503 DVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELRLLY 543
Score = 30.8 bits (68), Expect = 8.3
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 11/76 (14%)
Query: 677 IVRRYIATPNGVLRIYPGSLMDK------AFDPTRRQWYLHAVANPGLISLTGPYLDVGG 730
++ +Y + G R YPG + AFD R+WY+ A +P + + +DV G
Sbjct: 209 LIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVI---LVDVSG 265
Query: 731 A--GYVVTISHTIHSS 744
+ G +TI+ SS
Sbjct: 266 SMKGLRLTIAKQTVSS 281
>gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subunit
[Homo sapiens]
Length = 1137
Score = 83.2 bits (204), Expect = 1e-15
Identities = 116/503 (23%), Positives = 212/503 (42%), Gaps = 69/503 (13%)
Query: 84 MMEFDGNF-NTNVSRTISCDRLSTTVNSR------AFNPGRDLNSVLADNLKSNPGIKWQ 136
++E + +F N V+ +IS +L T V ++ LN+V +N + +P + WQ
Sbjct: 188 LLESNAHFSNLPVNTSISSVQLPTNVYNKDPDILNGVYMSEALNAVFVENFQRDPTLTWQ 247
Query: 137 YFSSEEGIFTVFPAHKFRCKG----SYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQ 192
YF S G F ++P K+ +++ R+R Y+ K IV+++D S+ +
Sbjct: 248 YFGSATGFFRIYPGIKWTPDENGVITFDCRNRGWYIQAA-TSPKDIVILVDVSGSMKGLR 306
Query: 193 LQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSS 252
+ IAK IL + E+D I+++ D V ++ C+K L A + + V
Sbjct: 307 MTIAKHTITTILDTLGENDFINIIAYNDYVH--YIEPCFKGILVQADRDNREHFKLLVEE 364
Query: 253 --VKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKAT 310
VK Q ++AFQ+++ K + + I+ +S D + ED
Sbjct: 365 LMVKGVGVVDQ---ALREAFQILKQF-QEAKQGSLCNQAIMLIS------DGAVED---- 410
Query: 311 LQVINEENSFLNNSVMILTYALMNDGVTGLKELAF---LRDLAEQNSGKYGVPDRMALPV 367
+ + E+ ++ + V + TY + +E++F ++ +A N G Y +A
Sbjct: 411 YEPVFEKYNWPDCKVRVFTYLIG-------REVSFADRMKWIACNNKGYYTQISTLA-DT 462
Query: 368 IKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCY---- 423
+ M L+ LS +D + S S L+ TV+ P +
Sbjct: 463 QENVMEYLHVLSRPMVINHDHDIIWTEAYMDSKLLS---SQAQSLTLLTTVAMPVFSKKN 519
Query: 424 ---FGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPY----- 475
+LLG+VG DV L +++ Y+ + Y FL + GY L HP L Y
Sbjct: 520 ETRSHGILLGVVGSDVALRELMKLAPRYKLGVHGYAFLNTNNGYILSHPDLRPLYREGKK 579
Query: 476 LLSEPPLHT-DIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEA 534
L +P ++ D+ E + E +R +++ G +LS + + GK
Sbjct: 580 LKPKPNYNSVDLSEVEWEDQAESLRTAMINRETG----------TLSMDVKVPMDKGKRV 629
Query: 535 YNVS--YAWKMVQDTSFILCIVV 555
++ Y + + DT F L +V+
Sbjct: 630 LFLTNDYFFTDISDTPFSLGVVL 652
Score = 34.3 bits (77), Expect = 0.75
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 12/121 (9%)
Query: 680 RYIATPNGVLRIYPGSLMDK------AFDPTRRQWYLHAVANPGLISLTGPYLDVGGA-- 731
+Y + G RIYPG FD R WY+ A +P I + +DV G+
Sbjct: 247 QYFGSATGFFRIYPGIKWTPDENGVITFDCRNRGWYIQAATSPKDIVI---LVDVSGSMK 303
Query: 732 GYVVTIS-HTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIM 790
G +TI+ HTI + L + ++ + + Y +L ++D + +
Sbjct: 304 GLRMTIAKHTITTILDTLGENDFINIIAYNDYVHYIEPCFKGILVQADRDNREHFKLLVE 363
Query: 791 E 791
E
Sbjct: 364 E 364
>gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 3 [Homo sapiens]
Length = 702
Score = 45.4 bits (106), Expect = 3e-04
Identities = 40/183 (21%), Positives = 79/183 (43%), Gaps = 17/183 (9%)
Query: 173 PQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYK 232
P K++V +LD AS+ T+L+ KDA IL + D+ S++ ++ ++ +K
Sbjct: 291 PLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKV------WK 344
Query: 233 TFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIY 292
L T ++ R ++ + S T Q+A +L+ ++ + +I++
Sbjct: 345 DHLISVTPDSIRDGKVYIHHM-SPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVF 403
Query: 293 LSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQ 352
L+ G + + TL+++N V I T + ND + L L+ +
Sbjct: 404 LTDGKPTVGETH-----TLKILNNTREAARGQVCIFTIGIGND-----VDFRLLEKLSLE 453
Query: 353 NSG 355
N G
Sbjct: 454 NCG 456
>gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 1 [Homo sapiens]
Length = 956
Score = 45.4 bits (106), Expect = 3e-04
Identities = 40/183 (21%), Positives = 79/183 (43%), Gaps = 17/183 (9%)
Query: 173 PQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYK 232
P K++V +LD AS+ T+L+ KDA IL + D+ S++ ++ ++ +K
Sbjct: 291 PLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKV------WK 344
Query: 233 TFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIY 292
L T ++ R ++ + S T Q+A +L+ ++ + +I++
Sbjct: 345 DHLISVTPDSIRDGKVYIHHM-SPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVF 403
Query: 293 LSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQ 352
L+ G + + TL+++N V I T + ND + L L+ +
Sbjct: 404 LTDGKPTVGETH-----TLKILNNTREAARGQVCIFTIGIGND-----VDFRLLEKLSLE 453
Query: 353 NSG 355
N G
Sbjct: 454 NCG 456
>gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 2 [Homo sapiens]
Length = 742
Score = 45.4 bits (106), Expect = 3e-04
Identities = 40/183 (21%), Positives = 79/183 (43%), Gaps = 17/183 (9%)
Query: 173 PQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYK 232
P K++V +LD AS+ T+L+ KDA IL + D+ S++ ++ ++ +K
Sbjct: 77 PLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKV------WK 130
Query: 233 TFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIY 292
L T ++ R ++ + S T Q+A +L+ ++ + +I++
Sbjct: 131 DHLISVTPDSIRDGKVYIHHM-SPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVF 189
Query: 293 LSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQ 352
L+ G + + TL+++N V I T + ND + L L+ +
Sbjct: 190 LTDGKPTVGETH-----TLKILNNTREAARGQVCIFTIGIGND-----VDFRLLEKLSLE 239
Query: 353 NSG 355
N G
Sbjct: 240 NCG 242
>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
[Homo sapiens]
Length = 890
Score = 38.1 bits (87), Expect = 0.052
Identities = 28/132 (21%), Positives = 56/132 (42%), Gaps = 7/132 (5%)
Query: 176 KHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFL 235
K++ ++D S+ +L+ K+A IL + E D ++ + + V T +K L
Sbjct: 283 KNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVST------WKEHL 336
Query: 236 SPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSA 295
AT E ++ TFV S++ T G + ++ + + ++I L+
Sbjct: 337 VQATPENLQEARTFVKSMEDK-GMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTD 395
Query: 296 GITSKDSSEEDK 307
G + S +K
Sbjct: 396 GDANVGESRPEK 407
>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
Length = 1313
Score = 37.7 bits (86), Expect = 0.068
Identities = 16/50 (32%), Positives = 32/50 (64%)
Query: 173 PQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTV 222
P K++V ++D +S+ T+++ K A VILS + +D ++++ +DTV
Sbjct: 279 PMEKNVVFVIDVSSSMFGTKMEQTKTAMNVILSDLQANDYFNIISFSDTV 328
>gi|4826988 ribosomal protein L3-like [Homo sapiens]
Length = 407
Score = 36.6 bits (83), Expect = 0.15
Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 9/96 (9%)
Query: 614 PYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSL 673
P + SQP Y A ++ R + PGLK S R EV E +T +E L
Sbjct: 33 PRDDPSQPVHLTAFLGYKAGMTHTLREVHRPGLKISKREEV--------EAVTIVETPPL 84
Query: 674 NTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWY 709
V Y+ATP G LR + + D RR++Y
Sbjct: 85 VVVGVVGYVATPRG-LRSFKTIFAEHLSDECRRRFY 119
>gi|169646754 angiopoietin 2 isoform c precursor [Homo sapiens]
Length = 444
Score = 35.4 bits (80), Expect = 0.34
Identities = 32/166 (19%), Positives = 69/166 (41%), Gaps = 16/166 (9%)
Query: 230 CYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKF------- 282
C TFL P + S +VS+ D+P ++ Q+ L NNT++
Sbjct: 41 CSYTFLLPEMDNCRSSSSPYVSNAVQRDAPLEYDDSVQRLQVLENIMENNTQWLMKVLNQ 100
Query: 283 QANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKE 342
++ ++ S + D+ + + + ++NSFL V+ A+ + + L+
Sbjct: 101 TTRLELQLLEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKKVL----AMEDKHIIQLQS 156
Query: 343 LAFLRD-----LAEQNSGKYGVPDRMALPVIKGSMMVLNQLSNLET 383
+ +D +++QNS + ++ + S++ Q +ET
Sbjct: 157 IKEEKDQLQVLVSKQNSIIEELEKKIVTATVNNSVLQKQQHDLMET 202
>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 2 [Homo sapiens]
Length = 754
Score = 35.0 bits (79), Expect = 0.44
Identities = 38/134 (28%), Positives = 51/134 (38%), Gaps = 38/134 (28%)
Query: 1091 SNLENDRDERDDDSHEDRGIISNTRFIAAV--IERHAHSPERRRRY---WGRSGTESDHG 1145
S N R D +H+ R S F AAV ++ HSP+ R+++ G SGTE+
Sbjct: 510 SGTSNSGRARSDPTHQHRH--SGGHFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAP-- 565
Query: 1146 YSTMSPQEDSENPPCNNDPLSAGVDVGNHD-EDLDLDTPPQTAALLSH----KFHHYRSH 1200
V V H ++ PQ AL H HH+ H
Sbjct: 566 ---------------------TQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHH 604
Query: 1201 HPTLHHSHHLQAAV 1214
H HH HH Q A+
Sbjct: 605 H---HHHHHGQQAL 615
>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 1 [Homo sapiens]
Length = 763
Score = 35.0 bits (79), Expect = 0.44
Identities = 38/134 (28%), Positives = 51/134 (38%), Gaps = 38/134 (28%)
Query: 1091 SNLENDRDERDDDSHEDRGIISNTRFIAAV--IERHAHSPERRRRY---WGRSGTESDHG 1145
S N R D +H+ R S F AAV ++ HSP+ R+++ G SGTE+
Sbjct: 519 SGTSNSGRARSDPTHQHRH--SGGHFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAP-- 574
Query: 1146 YSTMSPQEDSENPPCNNDPLSAGVDVGNHD-EDLDLDTPPQTAALLSH----KFHHYRSH 1200
V V H ++ PQ AL H HH+ H
Sbjct: 575 ---------------------TQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHH 613
Query: 1201 HPTLHHSHHLQAAV 1214
H HH HH Q A+
Sbjct: 614 H---HHHHHGQQAL 624
>gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]
Length = 1805
Score = 33.9 bits (76), Expect = 0.97
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 20/84 (23%)
Query: 906 LCLNCHRMEQNECECP-------CECPLEVNEC---TGNLTNAENRNPS--CEVHQEP-- 951
LC + R +C C C+CPL C G + N C HQ+
Sbjct: 550 LCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLY 609
Query: 952 ------VTYTAIDPGLQDALHQCV 969
+ Y+AI PGL + L CV
Sbjct: 610 TDTICEINYSAIHPGLCEDLRSCV 633
>gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]
Length = 1822
Score = 33.9 bits (76), Expect = 0.97
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 20/84 (23%)
Query: 906 LCLNCHRMEQNECECP-------CECPLEVNEC---TGNLTNAENRNPS--CEVHQEP-- 951
LC + R +C C C+CPL C G + N C HQ+
Sbjct: 550 LCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLY 609
Query: 952 ------VTYTAIDPGLQDALHQCV 969
+ Y+AI PGL + L CV
Sbjct: 610 TDTICEINYSAIHPGLCEDLRSCV 633
>gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]
Length = 1752
Score = 33.9 bits (76), Expect = 0.97
Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 20/84 (23%)
Query: 906 LCLNCHRMEQNECECP-------CECPLEVNEC---TGNLTNAENRNPS--CEVHQEP-- 951
LC + R +C C C+CPL C G + N C HQ+
Sbjct: 550 LCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGRCHCHQQSLY 609
Query: 952 ------VTYTAIDPGLQDALHQCV 969
+ Y+AI PGL + L CV
Sbjct: 610 TDTICEINYSAIHPGLCEDLRSCV 633
>gi|119220564 one cut domain, family member 2 [Homo sapiens]
Length = 504
Score = 33.9 bits (76), Expect = 0.97
Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
Query: 1151 PQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHH-YRSHHPTLHHSHH 1209
P + + C++ P G+ + N L P + +S KFHH + HHP HH HH
Sbjct: 126 PLHHAMSMSCDSSP--PGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHH 183
Query: 1210 LQ 1211
Q
Sbjct: 184 HQ 185
>gi|216548385 dachsous 2 isoform 2 [Homo sapiens]
Length = 1369
Score = 32.3 bits (72), Expect = 2.8
Identities = 27/118 (22%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 302 SSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPD 361
S++ + L+ +N+ + N S + + + ++ G + + L +Q+SG YG
Sbjct: 752 SAQAFVRVDLEDVNDNHPVFNPSTYVTS--ISDETQPGTEIINVLA--TDQDSGIYGT-- 805
Query: 362 RMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVS 419
+A +I G++ + L +++T G Y LP ++ SL S + G GL ++
Sbjct: 806 -VAYELIPGNV---SSLFTIDSTTGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVIN 859
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 32.0 bits (71), Expect = 3.7
Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Query: 293 LSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQ 352
+++ + S+ SSE D A IN + LN+S +++ L N+ + LA DL +
Sbjct: 194 VTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMN-GLRNNQRKAKRSLAPRFDLPDM 252
Query: 353 NSGKYGVPDRMALPVIK 369
KY V R A +K
Sbjct: 253 KETKYTVDKRKAEREVK 269
>gi|194733735 transient receptor potential cation channel, subfamily
C, member 3 isoform a [Homo sapiens]
Length = 921
Score = 32.0 bits (71), Expect = 3.7
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Query: 823 VANDILNHPNFV-KKNLCNSFSDRTVQR--FYKFN---TSLAGDLTNLVHGSHCSKYRLA 876
+ ILNHP F K L S ++ +Q FY ++ T + D+T ++ +HC KY +
Sbjct: 190 IVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVV 249
Query: 877 RI 878
+
Sbjct: 250 HM 251
>gi|4507687 transient receptor potential cation channel, subfamily
C, member 3 isoform b [Homo sapiens]
Length = 848
Score = 32.0 bits (71), Expect = 3.7
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Query: 823 VANDILNHPNFV-KKNLCNSFSDRTVQR--FYKFN---TSLAGDLTNLVHGSHCSKYRLA 876
+ ILNHP F K L S ++ +Q FY ++ T + D+T ++ +HC KY +
Sbjct: 117 IVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVV 176
Query: 877 RI 878
+
Sbjct: 177 HM 178
>gi|4505243 myelin protein zero [Homo sapiens]
Length = 258
Score = 32.0 bits (71), Expect = 3.7
Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 7/97 (7%)
Query: 1035 ITLNMIKSAP------VGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSV 1088
+TL + + P +G V GG++G +++L+L Y R+ RR L+A E
Sbjct: 152 VTLYVFEKVPTRYGVVLGAVIGGVLGVVLLLLLLFYVVRYCWLRRQAALQRRLSAMEKG- 210
Query: 1089 RMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHA 1125
++ D +R + ++ ++R AV E+ A
Sbjct: 211 KLHKPGKDASKRGRQTPVLYAMLDHSRSTKAVSEKKA 247
>gi|166295173 kin of IRRE like [Homo sapiens]
Length = 757
Score = 32.0 bits (71), Expect = 3.7
Identities = 19/91 (20%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Query: 1031 GDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRM 1090
G +I L + PVG +AG +G ++L+ A ++RR + +++ +++
Sbjct: 481 GTAIIQLEEREVLPVGIIAGATIGASILLIFFFIALVFFLYRRRKGSRKDVTLRKLDIKV 540
Query: 1091 SNLENDRDERDDDSHEDRGIISN-TRFIAAV 1120
+ + D +D +S TR + A+
Sbjct: 541 ETVNREPLTMHSDREDDTASVSTATRVMKAI 571
>gi|110578665 seven in absentia homolog 3 [Homo sapiens]
Length = 269
Score = 32.0 bits (71), Expect = 3.7
Identities = 11/28 (39%), Positives = 16/28 (57%)
Query: 1192 HKFHHYRSHHPTLHHSHHLQAAVTVHTV 1219
H+ HH+ HH HH HH +A + + V
Sbjct: 75 HRHHHHLRHHAHPHHLHHQEAGLHANPV 102
>gi|55770830 chromobox homolog 4 [Homo sapiens]
Length = 560
Score = 31.6 bits (70), Expect = 4.8
Identities = 28/108 (25%), Positives = 40/108 (37%), Gaps = 18/108 (16%)
Query: 1120 VIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDS--ENPPCNNDPLSAGV------DV 1171
V E A SP ++R +D + + E+ E PP + +GV D
Sbjct: 284 VAEGEARSPSHKKRAADERHPPADRTFKKAAGAEEKKVEAPPKRREEEVSGVSDPQPQDA 343
Query: 1172 GNH----------DEDLDLDTPPQTAALLSHKFHHYRSHHPTLHHSHH 1209
G+ ++ L L T P A + H SHHP H HH
Sbjct: 344 GSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARNTHPPSHHPHPHPHHH 391
>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
Length = 1073
Score = 31.6 bits (70), Expect = 4.8
Identities = 11/29 (37%), Positives = 15/29 (51%)
Query: 1183 PPQTAALLSHKFHHYRSHHPTLHHSHHLQ 1211
P Q + + H+ HH +HH HHLQ
Sbjct: 205 PQQNVVINGNAHPHHLHHHHQIHHGHHLQ 233
>gi|208431827 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform a [Homo sapiens]
Length = 551
Score = 31.2 bits (69), Expect = 6.3
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 293 LSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQ 352
+++ + S+ SSE D A IN + LN+S +++ L N+ + LA DL +
Sbjct: 194 VTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMN-GLRNNQRKAKRSLAPRFDLPDM 252
Query: 353 NSGKYGVPDRMAL 365
KY V R +
Sbjct: 253 KETKYTVDKRFGM 265
>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
2 isoform a [Homo sapiens]
Length = 551
Score = 31.2 bits (69), Expect = 6.3
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 293 LSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQ 352
+++ + S+ SSE D A IN + LN+S +++ L N+ + LA DL +
Sbjct: 194 VTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMN-GLRNNQRKAKRSLAPRFDLPDM 252
Query: 353 NSGKYGVPDRMAL 365
KY V R +
Sbjct: 253 KETKYTVDKRFGM 265
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,841,275
Number of Sequences: 37866
Number of extensions: 2173012
Number of successful extensions: 5601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 5521
Number of HSP's gapped (non-prelim): 60
length of query: 1223
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1109
effective length of database: 13,930,794
effective search space: 15449250546
effective search space used: 15449250546
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.