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Search of human proteins with 166706917
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|166706917 hypothetical protein LOC199920 [Homo sapiens]
(728 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|166706917 hypothetical protein LOC199920 [Homo sapiens] 1476 0.0
gi|42476118 FYN binding protein (FYB-120/130) isoform 1 [Homo sa... 142 8e-34
gi|40788007 FYN binding protein (FYB-120/130) isoform 2 [Homo sa... 134 2e-31
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] 58 4e-08
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int... 49 2e-05
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 46 1e-04
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 46 1e-04
gi|210032580 SET domain containing 1B [Homo sapiens] 44 5e-04
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 43 0.001
gi|18093112 ABT1-associated protein [Homo sapiens] 43 0.001
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 42 0.002
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 42 0.003
gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sa... 42 0.003
gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo s... 42 0.003
gi|22027646 angiomotin like 1 [Homo sapiens] 41 0.003
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 40 0.006
gi|62244004 modulator of estrogen induced transcription isoform ... 40 0.006
gi|63176611 modulator of estrogen induced transcription isoform ... 40 0.006
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 40 0.006
gi|38570058 hypothetical protein LOC80129 [Homo sapiens] 40 0.008
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 40 0.008
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 40 0.008
gi|41055989 M-phase phosphoprotein 8 [Homo sapiens] 40 0.008
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 40 0.008
gi|239047795 pleckstrin homology domain containing, family A mem... 40 0.010
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 40 0.010
gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens] 39 0.013
gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens] 39 0.013
gi|110349719 titin isoform N2-A [Homo sapiens] 39 0.013
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 39 0.013
>gi|166706917 hypothetical protein LOC199920 [Homo sapiens]
Length = 728
Score = 1476 bits (3820), Expect = 0.0
Identities = 728/728 (100%), Positives = 728/728 (100%)
Query: 1 MEGEGVRNFKELRAKFQNLDAPPLPGPIKFPAGVSPKGDIGGTQSTQILANGKPLSSNHK 60
MEGEGVRNFKELRAKFQNLDAPPLPGPIKFPAGVSPKGDIGGTQSTQILANGKPLSSNHK
Sbjct: 1 MEGEGVRNFKELRAKFQNLDAPPLPGPIKFPAGVSPKGDIGGTQSTQILANGKPLSSNHK 60
Query: 61 QRTPYCSSSESQPLQPQKIKLAQKSEIPKCSNSPGPLGKSTVCSATSSQKASLLLEVTQS 120
QRTPYCSSSESQPLQPQKIKLAQKSEIPKCSNSPGPLGKSTVCSATSSQKASLLLEVTQS
Sbjct: 61 QRTPYCSSSESQPLQPQKIKLAQKSEIPKCSNSPGPLGKSTVCSATSSQKASLLLEVTQS 120
Query: 121 NVEIITKEKVMVANSFRNKLWNWEKVSSQKSEMSSALLLANYGSKAIHLEGQKGMGLTPE 180
NVEIITKEKVMVANSFRNKLWNWEKVSSQKSEMSSALLLANYGSKAIHLEGQKGMGLTPE
Sbjct: 121 NVEIITKEKVMVANSFRNKLWNWEKVSSQKSEMSSALLLANYGSKAIHLEGQKGMGLTPE 180
Query: 181 EPRKKLETKGAQTLPSQKHVVAPKILHNVSEDPSFVISQHIRKSWENPPPERSPASSPCQ 240
EPRKKLETKGAQTLPSQKHVVAPKILHNVSEDPSFVISQHIRKSWENPPPERSPASSPCQ
Sbjct: 181 EPRKKLETKGAQTLPSQKHVVAPKILHNVSEDPSFVISQHIRKSWENPPPERSPASSPCQ 240
Query: 241 PIYECELASQAPEKQPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQPAAV 300
PIYECELASQAPEKQPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQPAAV
Sbjct: 241 PIYECELASQAPEKQPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQPAAV 300
Query: 301 PKTQGEVTVEEGSLSPERLFNAEFEEPHNYEATISYLRHSGNSINLCTAKEIADPTYEVG 360
PKTQGEVTVEEGSLSPERLFNAEFEEPHNYEATISYLRHSGNSINLCTAKEIADPTYEVG
Sbjct: 301 PKTQGEVTVEEGSLSPERLFNAEFEEPHNYEATISYLRHSGNSINLCTAKEIADPTYEVG 360
Query: 361 IEELQKPGKNFPYPEPSAKHEDKKMKEKQPCELKPKNTEKEPYSNHVFKVDACEGTPEKI 420
IEELQKPGKNFPYPEPSAKHEDKKMKEKQPCELKPKNTEKEPYSNHVFKVDACEGTPEKI
Sbjct: 361 IEELQKPGKNFPYPEPSAKHEDKKMKEKQPCELKPKNTEKEPYSNHVFKVDACEGTPEKI 420
Query: 421 QMTNVHTGRRNMLAGKQEAMIDIIQTNPCPEGPKLARHSQGHCGHLEVLESTKETPDLGV 480
QMTNVHTGRRNMLAGKQEAMIDIIQTNPCPEGPKLARHSQGHCGHLEVLESTKETPDLGV
Sbjct: 421 QMTNVHTGRRNMLAGKQEAMIDIIQTNPCPEGPKLARHSQGHCGHLEVLESTKETPDLGV 480
Query: 481 SKTSSISEEIYDDVEYSRKEVPKLNYSSSLASSSEENRELYEDVYKTKNNYPKIDLDGKE 540
SKTSSISEEIYDDVEYSRKEVPKLNYSSSLASSSEENRELYEDVYKTKNNYPKIDLDGKE
Sbjct: 481 SKTSSISEEIYDDVEYSRKEVPKLNYSSSLASSSEENRELYEDVYKTKNNYPKIDLDGKE 540
Query: 541 ALKRLQQFFKKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYDDVDLSEKESKDE 600
ALKRLQQFFKKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYDDVDLSEKESKDE
Sbjct: 541 ALKRLQQFFKKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYDDVDLSEKESKDE 600
Query: 601 DKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRERFKYD 660
DKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRERFKYD
Sbjct: 601 DKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRERFKYD 660
Query: 661 KEIIVINTAVACSNNSRNGIFDLPISPGEELEVIDTTEQNLVICRNSKGKYGYVLIEHLD 720
KEIIVINTAVACSNNSRNGIFDLPISPGEELEVIDTTEQNLVICRNSKGKYGYVLIEHLD
Sbjct: 661 KEIIVINTAVACSNNSRNGIFDLPISPGEELEVIDTTEQNLVICRNSKGKYGYVLIEHLD 720
Query: 721 FKHQSWSP 728
FKHQSWSP
Sbjct: 721 FKHQSWSP 728
>gi|42476118 FYN binding protein (FYB-120/130) isoform 1 [Homo
sapiens]
Length = 829
Score = 142 bits (359), Expect = 8e-34
Identities = 146/517 (28%), Positives = 228/517 (44%), Gaps = 82/517 (15%)
Query: 250 QAPEKQPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQPAAVPKTQGEVTV 309
Q+ EK+ ++ PK KPLP + +LGPPPPKP+RPP V+L F + + ++G+ +
Sbjct: 328 QSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSY 387
Query: 310 EEGSLSPERLFNAEFEEP----HNYEATISYLRHSGNSINLCTAKEIADPTYEV---GI- 361
SL P + + P H + + L N+ ++ P E G+
Sbjct: 388 STTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPR----NIKPPFDLKSPVNEDNQDGVT 443
Query: 362 ---------EELQKPGKNFPYPEPSAKHEDKKMK-EKQPCEL-KPKNTEKEPYSNHVFKV 410
EE G+ + E S + E K+ K EK+ EL K + EKE + K
Sbjct: 444 HSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEKEKKEQEIKKK 503
Query: 411 DACEGTPEKIQMTNV---HTGRRNMLAGKQEAMIDIIQTNPCPEGPKLARHSQGHCGHLE 467
G + I + G +N L+ KQ I+II+ PEG L R ++G G+++
Sbjct: 504 FKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYIK 563
Query: 468 VLESTKETPDLGVSKTS--------SISEEIYDDVEYSRKEVPKLNYSSSLASSSEENRE 519
+ L + K S +E+YDDV E ++ S S
Sbjct: 564 TTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDV----AEQDDISSHSQSGSGGIFPPP 619
Query: 520 LYEDVYKTKNNYPKIDLDGKEALK----------RLQQFFKKEKDRFKIKKTKSK----E 565
+D+Y + + D D L+ + + K + DR K + K K +
Sbjct: 620 PDDDIY---DGIEEEDADDGSTLQVQEKSNTWSWGILKMLKGKDDRKKSIREKPKVSDSD 676
Query: 566 NLSAFSILLPDLELKSQEVIIYDDVDLSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEES 625
N S P +L + +YDDVD S+ + AE S
Sbjct: 677 NNEGSSFPAPPKQLDMGDE-VYDDVDTSD----------------------FPVSSAEMS 713
Query: 626 ESFSPRNFFKTKKQNLEK-NRMKREEKLFRERFKYDKEI-IVINTAVACSNNSRN-GIFD 682
+ + KT++++L+K + ++EEK FR++FKYD EI ++ +T V S S+ G D
Sbjct: 714 QGTNVGK-AKTEEKDLKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRD 772
Query: 683 LPISPGEELEVIDTTEQNLVICRNSKGKYGYVLIEHL 719
L + PGE LEVI TT+ V+CRN +GKYGYVL +L
Sbjct: 773 LQVKPGESLEVIQTTDDTKVLCRNEEGKYGYVLRSYL 809
Score = 44.3 bits (103), Expect = 4e-04
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 17/117 (14%)
Query: 614 KEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRE---RFKYDKEIIVINTAV 670
KE+++K EE K+ LEK K +EK +E +FK I VI+ A
Sbjct: 469 KEREKKREKEEK-----------KRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAK 517
Query: 671 ACSNNSRNGIFDLPISPGEELEVIDTTE--QNLVICRNSKGKYGYVLIEHLDFKHQS 725
AC + + G +L GE++E+I T+ + + R ++G YGY+ ++ + S
Sbjct: 518 ACC-DVKGGKNELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYIKTTAVEIDYDS 573
>gi|40788007 FYN binding protein (FYB-120/130) isoform 2 [Homo
sapiens]
Length = 783
Score = 134 bits (338), Expect = 2e-31
Identities = 137/498 (27%), Positives = 225/498 (45%), Gaps = 90/498 (18%)
Query: 250 QAPEKQPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQPAAVPKTQGEVTV 309
Q+ EK+ ++ PK KPLP + +LGPPPPKP+RPP V+L F + + ++G+ +
Sbjct: 328 QSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSY 387
Query: 310 EEGSLSPERLFNAEFEEP----HNYEATISYLRHSGNSINLCTAKEIADPTYEV---GI- 361
SL P + + P H + + L N+ ++ P E G+
Sbjct: 388 STTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPR----NIKPPFDLKSPVNEDNQDGVT 443
Query: 362 ---------EELQKPGKNFPYPEPSAKHEDKKMK-EKQPCEL-KPKNTEKEPYSNHVFKV 410
EE G+ + E S + E K+ K EK+ EL K + EKE + K
Sbjct: 444 HSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEKEKKEQEIKKK 503
Query: 411 DACEGTPEKIQMTNV---HTGRRNMLAGKQEAMIDIIQTNPCPEGPKLARHSQGHCGHLE 467
G + I + G +N L+ KQ I+II+ PEG L R ++G G++
Sbjct: 504 FKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYI- 562
Query: 468 VLESTKETPDLGVSKTSSISEEIYDDVEYSRKEVPKLNYSSSLASSS---EENRELYEDV 524
KT+++ +++Y ++ K SL + S E+++E+Y+DV
Sbjct: 563 --------------KTTAV------EIDYDSLKLKK----DSLGAPSRPIEDDQEVYDDV 598
Query: 525 YKTKNNYPKIDLDGKEALKRLQQFFKKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEV 584
+ +++ G + F D + ++ F L++ +
Sbjct: 599 AE-QDDISSHSQSGSGGI------FPPPPDDDIYDGIEEEDADDGFPAPPKQLDMGDE-- 649
Query: 585 IIYDDVDLSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKTKKQNLEK- 643
+YDDVD S+ + AE S+ + KT++++L+K
Sbjct: 650 -VYDDVDTSD----------------------FPVSSAEMSQGTNVGK-AKTEEKDLKKL 685
Query: 644 NRMKREEKLFRERFKYDKEI-IVINTAVACSNNSRN-GIFDLPISPGEELEVIDTTEQNL 701
+ ++EEK FR++FKYD EI ++ +T V S S+ G DL + PGE LEVI TT+
Sbjct: 686 KKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGESLEVIQTTDDTK 745
Query: 702 VICRNSKGKYGYVLIEHL 719
V+CRN +GKYGYVL +L
Sbjct: 746 VLCRNEEGKYGYVLRSYL 763
Score = 44.3 bits (103), Expect = 4e-04
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 17/117 (14%)
Query: 614 KEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRE---RFKYDKEIIVINTAV 670
KE+++K EE K+ LEK K +EK +E +FK I VI+ A
Sbjct: 469 KEREKKREKEEK-----------KRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAK 517
Query: 671 ACSNNSRNGIFDLPISPGEELEVIDTTE--QNLVICRNSKGKYGYVLIEHLDFKHQS 725
AC + + G +L GE++E+I T+ + + R ++G YGY+ ++ + S
Sbjct: 518 ACC-DVKGGKNELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYIKTTAVEIDYDS 573
>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
Length = 669
Score = 57.8 bits (138), Expect = 4e-08
Identities = 52/179 (29%), Positives = 83/179 (46%), Gaps = 15/179 (8%)
Query: 545 LQQFFKKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYDDV---DLSEKESKDED 601
+Q F + +++T+S L D+ + + +YDDV D S K D
Sbjct: 466 MQSFRRPSAASIDLRRTRSAAGLHFQDRQPEDIPVPDEIYELYDDVEPRDDSSPSPKGRD 525
Query: 602 KLKMWKPKFLTPKE----KKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRERF 657
+ + P + +KEK+ + + P + K KQ + + +RE FR++F
Sbjct: 526 EAPSVQQAARRPPQDPALRKEKD--PQPQQLPPMDP-KLLKQLRKAEKAERE---FRKKF 579
Query: 658 KYDKEIIVINTAVACSN--NSRNGIFDLPISPGEELEVIDTTEQNLVICRNSKGKYGYV 714
K++ EI+V + N R G L I GE LEVI+ T ++CR+ KGKYGYV
Sbjct: 580 KFEGEIVVHTKMMIDPNAKTRRGGGKHLGIRRGEILEVIEFTSNEEMLCRDPKGKYGYV 638
Score = 45.1 bits (105), Expect = 2e-04
Identities = 22/46 (47%), Positives = 30/46 (65%), Gaps = 1/46 (2%)
Query: 255 QPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPP-IVNLQAFQRQPAA 299
+P +R H P+ +PLP SLG PP KP PP V++Q+F+R AA
Sbjct: 430 RPGLRPSHPPRRRPLPPASSLGHPPAKPPLPPGPVDMQSFRRPSAA 475
Score = 31.6 bits (70), Expect = 2.7
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 11/83 (13%)
Query: 221 IRKSWENPPPERSPASSPCQPIYECELASQAPEKQPDVRHHHLPKTKPLPSID--SLGPP 278
I+ ++ PE P+ P +P + E QP++ H PK PLP SL PP
Sbjct: 18 IKAKFQASQPE--PSDLPKKPP-KPEFGKLKKFSQPELSEH--PKKAPLPEFGAVSLKPP 72
Query: 279 PPK----PSRPPIVNLQAFQRQP 297
PP+ P +PP + ++P
Sbjct: 73 PPEVTDLPKKPPPPEVTDLPKKP 95
Score = 30.4 bits (67), Expect = 6.1
Identities = 35/120 (29%), Positives = 47/120 (39%), Gaps = 20/120 (16%)
Query: 217 ISQHIRKSWENPPPERSPASSPCQPIYECELASQAPEKQPDVRHHHLPKTKPLPSIDSL- 275
+S+H +K+ P PE S P +L P+K P LPK P P + L
Sbjct: 52 LSEHPKKA---PLPEFGAVSLKPPPPEVTDL----PKKPPPPEVTDLPKKPPPPEVTDLP 104
Query: 276 -GPPPP-------KPSRPPIVNLQAFQRQPAAVPKTQGEVTVEEGSLSPERLFNAEFEEP 327
PPPP KPS+ + +L Q A P + + E G E A EP
Sbjct: 105 KKPPPPEVTDLPKKPSKLELSDLSKKFPQLGATPFPRKPLQPEVG----EAPLKASLPEP 160
>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
interacting protein [Homo sapiens]
Length = 1211
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/166 (29%), Positives = 65/166 (39%), Gaps = 21/166 (12%)
Query: 217 ISQHIRKSWENPPPERSPASSPCQPIYECELASQAPEKQPDVRHHHLPKTKPLPSIDSLG 276
IS HI PPP SP P P ++ + +S++ + R KPL +
Sbjct: 745 ISDHI------PPPPLSPPPPPPLPFHDAKPSSRSSDGS---RGPAQALAKPLTQLSHPV 795
Query: 277 PPPPKPSRPPIVNLQAFQRQPAAVPKTQGEVTVEEGSLSPERLFNAEFEEPHNYEATI-S 335
PPPP P PP V P + + G E +S +RL +E+ N E TI
Sbjct: 796 PPPPPPPLPPPVPC-----APPMLSRGLGHRRSETSHMSVKRL---RWEQVENSEGTIWG 847
Query: 336 YLRHSGNSINLCTAKEIADPTYEVGIEELQKPGKNFPYPEPSAKHE 381
L + L + D G QKP K P PEP K E
Sbjct: 848 QLGEDSDYDKLSDMVKYLDLELHFG---TQKPAKPVPGPEPFRKKE 890
Score = 33.5 bits (75), Expect = 0.72
Identities = 38/160 (23%), Positives = 58/160 (36%), Gaps = 21/160 (13%)
Query: 233 SPASSPCQPIYECELASQAPEKQPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPPIVNLQA 292
SP+SS P + +S+AP QP P P PP P P+RPP
Sbjct: 621 SPSSSESHPYASLD-SSRAPSPQPG----------PGPICPD-SPPSPDPTRPPSRRKLF 668
Query: 293 FQRQPAAVPKTQGEVTVEEGSLSPERLFNAEFEEPHNYEATISYLRHSGNSIN------- 345
P T + V L P +F P N +S+ G+ +
Sbjct: 669 TFSHPVRSRDTDRFLDVLSEQLGPRVTIVDDFLTPENDYEEMSFHDDQGSFVTNERSSAS 728
Query: 346 --LCTAKEIADPTYEVGIEELQKPGKNFPYPEPSAKHEDK 383
+ +++E + TY + + P + P P P H+ K
Sbjct: 729 DCISSSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDAK 768
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 45.8 bits (107), Expect = 1e-04
Identities = 137/665 (20%), Positives = 239/665 (35%), Gaps = 76/665 (11%)
Query: 41 GGTQSTQILANGKPL----SSNHKQRTPYCSSSESQPLQPQK-----IKLAQKSEIPKCS 91
G +TQ L + PL SS H+ P Q K + +A+ E+
Sbjct: 218 GADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLL 277
Query: 92 NSPGPLGKSTVCSATSSQKASLLLEVTQSNVEIITKEKVMVANSFRNKLWNWEKVSSQKS 151
PL S + S+ N++ T++ ++ S +++ K+
Sbjct: 278 KREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICES--------KQILPSKT 329
Query: 152 EMSSALLLANYGSKAIHLEGQKGM----GLTPEEPRKKLETKGAQT--LPSQKHVVAPKI 205
+ SAL Y K E M + +E RK+ E + +T Q+ PK
Sbjct: 330 PLPSAL--DEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKS 387
Query: 206 LHNVSEDPSFVISQHIRKSWENPPPERSPASSPCQPIYECELASQAPEKQPDVRHHHLPK 265
+ + PS V+ S E + ++S C I E + +K+ V H K
Sbjct: 388 FKSKKQKPSRVLYSSTESSDEEALQNKKISTS-CSVIPETSNSDMQTKKEYVVSGEHKQK 446
Query: 266 TKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQPAAVPKTQGEVTVEEGSLSPERLFNAEFE 325
K + K N + Q + +TV G E+
Sbjct: 447 GKVKRKL--------KNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKT-----R 493
Query: 326 EPHNYEATISYLRHSGNSINLCTAKEIADPTYEVGIEELQKPGKNFPYPEPSAKHEDKKM 385
E N+ + S S++L P + G+ E Q + + +M
Sbjct: 494 EEGNFRKSFS--PKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEM 551
Query: 386 KEKQPCELKPKNTEKEPYSNHVFKVDACEGTPEKIQMTNVHT--GRRNMLAGKQEAMIDI 443
QP ++ NTE E + V +C+ + + H G ++ K E
Sbjct: 552 S-LQPDLVRYDNTESE-FLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPT 609
Query: 444 IQTNPCP------EGPKLARHSQGHCG-----HLEVLESTKETPDLGVSKTSSISEEIYD 492
+ + C EG L +H H H + +E KE KT ++E+
Sbjct: 610 FENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEK-----YKTKDSAKELQR 664
Query: 493 DVEYSRKEVPKLNYSSS-----LASSSEENRELYEDVYKTKNNYPKIDLDGKEALKRLQQ 547
VE+ R E K N+ S L + E E K + N K D KE ++
Sbjct: 665 SVEFDR-EFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNI-KDDKSTKEKHVSKER 722
Query: 548 FFKKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYDDVDLSEKE-SKDEDKLKMW 606
FK+E+D+ K + KS + DL+ + + + D + + S E+ + +
Sbjct: 723 NFKEERDKIKKESEKSFREEK-----IKDLKEERENIPTDKDSEFTSLGMSAIEESIGLH 777
Query: 607 KPKFLTPKEKKEKNGAEESESFSPRNFFKTKK-QNLEKNRMKREEKLFRERFKYDKEIIV 665
+ EK+EK+ E E R+ K K + +E+ ++E+K+ E K +K+ +
Sbjct: 778 LVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEH-KSEKDKLD 836
Query: 666 INTAV 670
++ V
Sbjct: 837 LSECV 841
Score = 33.9 bits (76), Expect = 0.55
Identities = 52/214 (24%), Positives = 85/214 (39%), Gaps = 40/214 (18%)
Query: 469 LESTKETPDLGVSKTSSISEEIYDDVEYSRKEVPKLNYSSSLASSSEENRELYEDVYKTK 528
++ +KE P+ K S I E+ + +E RK K S ++ +L E V K K
Sbjct: 792 IKESKEKPE----KRSQIKEKDIEKME--RKTFEKEKKIKHEHKSEKDKLDLSECVDKIK 845
Query: 529 NNYPKIDLDGKEALKRLQQFFKKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYD 588
D ++ + +K K+ IKKT +E KS+E +
Sbjct: 846 EK----DKLYSHHTEKCHKEGEKSKNTAAIKKTDDRE--------------KSREKM--- 884
Query: 589 DVDLSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKR 648
D +++ + E L K K L K+ K+ + +E S+S +N K K + L+K R
Sbjct: 885 DRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKN--KEKDRELDKKEKSR 942
Query: 649 EEKLFRERFKYDKEIIVINTAVACSNNSRNGIFD 682
DKE I I + ++ I D
Sbjct: 943 -----------DKESINITNSKHIQEEKKSSIVD 965
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 45.8 bits (107), Expect = 1e-04
Identities = 137/665 (20%), Positives = 239/665 (35%), Gaps = 76/665 (11%)
Query: 41 GGTQSTQILANGKPL----SSNHKQRTPYCSSSESQPLQPQK-----IKLAQKSEIPKCS 91
G +TQ L + PL SS H+ P Q K + +A+ E+
Sbjct: 241 GADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLL 300
Query: 92 NSPGPLGKSTVCSATSSQKASLLLEVTQSNVEIITKEKVMVANSFRNKLWNWEKVSSQKS 151
PL S + S+ N++ T++ ++ S +++ K+
Sbjct: 301 KREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICES--------KQILPSKT 352
Query: 152 EMSSALLLANYGSKAIHLEGQKGM----GLTPEEPRKKLETKGAQT--LPSQKHVVAPKI 205
+ SAL Y K E M + +E RK+ E + +T Q+ PK
Sbjct: 353 PLPSAL--DEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKS 410
Query: 206 LHNVSEDPSFVISQHIRKSWENPPPERSPASSPCQPIYECELASQAPEKQPDVRHHHLPK 265
+ + PS V+ S E + ++S C I E + +K+ V H K
Sbjct: 411 FKSKKQKPSRVLYSSTESSDEEALQNKKISTS-CSVIPETSNSDMQTKKEYVVSGEHKQK 469
Query: 266 TKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQPAAVPKTQGEVTVEEGSLSPERLFNAEFE 325
K + K N + Q + +TV G E+
Sbjct: 470 GKVKRKL--------KNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKT-----R 516
Query: 326 EPHNYEATISYLRHSGNSINLCTAKEIADPTYEVGIEELQKPGKNFPYPEPSAKHEDKKM 385
E N+ + S S++L P + G+ E Q + + +M
Sbjct: 517 EEGNFRKSFS--PKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEM 574
Query: 386 KEKQPCELKPKNTEKEPYSNHVFKVDACEGTPEKIQMTNVHT--GRRNMLAGKQEAMIDI 443
QP ++ NTE E + V +C+ + + H G ++ K E
Sbjct: 575 S-LQPDLVRYDNTESE-FLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPT 632
Query: 444 IQTNPCP------EGPKLARHSQGHCG-----HLEVLESTKETPDLGVSKTSSISEEIYD 492
+ + C EG L +H H H + +E KE KT ++E+
Sbjct: 633 FENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEK-----YKTKDSAKELQR 687
Query: 493 DVEYSRKEVPKLNYSSS-----LASSSEENRELYEDVYKTKNNYPKIDLDGKEALKRLQQ 547
VE+ R E K N+ S L + E E K + N K D KE ++
Sbjct: 688 SVEFDR-EFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNI-KDDKSTKEKHVSKER 745
Query: 548 FFKKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYDDVDLSEKE-SKDEDKLKMW 606
FK+E+D+ K + KS + DL+ + + + D + + S E+ + +
Sbjct: 746 NFKEERDKIKKESEKSFREEK-----IKDLKEERENIPTDKDSEFTSLGMSAIEESIGLH 800
Query: 607 KPKFLTPKEKKEKNGAEESESFSPRNFFKTKK-QNLEKNRMKREEKLFRERFKYDKEIIV 665
+ EK+EK+ E E R+ K K + +E+ ++E+K+ E K +K+ +
Sbjct: 801 LVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEH-KSEKDKLD 859
Query: 666 INTAV 670
++ V
Sbjct: 860 LSECV 864
Score = 33.9 bits (76), Expect = 0.55
Identities = 52/214 (24%), Positives = 85/214 (39%), Gaps = 40/214 (18%)
Query: 469 LESTKETPDLGVSKTSSISEEIYDDVEYSRKEVPKLNYSSSLASSSEENRELYEDVYKTK 528
++ +KE P+ K S I E+ + +E RK K S ++ +L E V K K
Sbjct: 815 IKESKEKPE----KRSQIKEKDIEKME--RKTFEKEKKIKHEHKSEKDKLDLSECVDKIK 868
Query: 529 NNYPKIDLDGKEALKRLQQFFKKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYD 588
D ++ + +K K+ IKKT +E KS+E +
Sbjct: 869 EK----DKLYSHHTEKCHKEGEKSKNTAAIKKTDDRE--------------KSREKM--- 907
Query: 589 DVDLSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKR 648
D +++ + E L K K L K+ K+ + +E S+S +N K K + L+K R
Sbjct: 908 DRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKN--KEKDRELDKKEKSR 965
Query: 649 EEKLFRERFKYDKEIIVINTAVACSNNSRNGIFD 682
DKE I I + ++ I D
Sbjct: 966 -----------DKESINITNSKHIQEEKKSSIVD 988
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 43.9 bits (102), Expect = 5e-04
Identities = 72/298 (24%), Positives = 113/298 (37%), Gaps = 51/298 (17%)
Query: 99 KSTVCSATSSQKASLLLEVTQSNVEIITKEKVMVANSFRNKLWNWEKVSSQKSEMSSALL 158
K+ S++ S ++S ++S+ E+ +VA E+ ++ EM +
Sbjct: 1106 KAEATSSSESSESSEFESSSESSPSSSEDEEEVVARE--------EEEEEEEEEMVAEES 1157
Query: 159 LANYGSKAIHLEGQKGMGLTPEEPRKKLETKGAQT-LPSQKHVVAPKILHNVSEDPSFVI 217
+A+ G + +G++ L P P +++ G + + + VAP+ ++ ++P +
Sbjct: 1158 MASAGPEDFEQDGEEA-ALAPGAPA--VDSLGMEEEVDIETEAVAPEERPSMLDEPPLPV 1214
Query: 218 SQHIRKSWENPPPERSPAS------SPCQPIYECELASQ-APEKQPDVRHHHL------P 264
PP E + SP P E E +PE+ P+ H L P
Sbjct: 1215 GVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPE---HDLEVEPEPP 1271
Query: 265 KTKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQPAAVPKTQGEVTVEEGSLSPERLFNAEF 324
PLP L PPP+P RPP P P+T S+ PE L AE
Sbjct: 1272 MMLPLPLQPPL--PPPRPPRPP---------SPPPEPET---TDASHPSVPPEPL--AED 1315
Query: 325 EEPHNYEATISYLRHSGNSINLCTAKEIADPTYEVGIEEL-----QKPGKNFPYPEPS 377
PH S + S A +P G L Q PG F YP PS
Sbjct: 1316 HPPHTPGLCGSLAK--SQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPS 1371
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 43.1 bits (100), Expect = 0.001
Identities = 47/238 (19%), Positives = 103/238 (43%), Gaps = 27/238 (11%)
Query: 451 EGPKLARHSQGHCGHLEVLESTKETPDLGVSKTSSISEEIYDDVEYSRKEVPKLNYSSSL 510
EG + +H H KE +S+ + Y+ + +K + + L
Sbjct: 625 EGKVVKKHKTKH------KHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDL 678
Query: 511 ASSSEENRELYE-DVYKTKNNYPKIDLDGKEALKRLQQFFKKEKDRFK-----IKKTKSK 564
++ ++ ++ D +K + K+ L+ KE L + ++ K+ KD K ++ K +
Sbjct: 679 STENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDR 738
Query: 565 ENLSAFSILLPDLELKSQEVIIYDDVDLSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEE 624
N + L + K +++ +Y + E++ K +D+ P + ++KN +E
Sbjct: 739 SNKAEKERSLKEKSPKEEKLRLYKE----ERKKKSKDR----------PSKLEKKNDLKE 784
Query: 625 SE-SFSPRNFFKTKKQNLEKNRMKREEKLFRERFKYDKEIIVINTAVACSNNSRNGIF 681
+ S FK K+ L+K ++ RE+ F E ++ + +T + S++ R+ F
Sbjct: 785 DKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWF 842
>gi|18093112 ABT1-associated protein [Homo sapiens]
Length = 851
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/161 (24%), Positives = 76/161 (47%), Gaps = 31/161 (19%)
Query: 495 EYSRKEVPKLNYSSSLASSSEENRELYEDVYKTKNNYPKIDLDGKEALKRLQQFFKKEKD 554
++ ++E+ +++ + LASSSE+ E+ E++ ++ ++ DGK K +KD
Sbjct: 525 KFKKEELLDMDFQAYLASSSEDEEEIEEELQG--DDGVNVEEDGKTK--------KSQKD 574
Query: 555 RFKIKKTKSKENLSAFSILLPDLELKSQEVIIYDDVDLSEKESKDEDKLKMWKPKFLTPK 614
+E ++ + LL ++ K ++ KE+ E ++K W P
Sbjct: 575 --------DEEQIAKYRQLLQVIQEKEKK----------GKENDMEMEIK-WVPGLKESA 615
Query: 615 EKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRE 655
E+ KN E + +P F KK+ EK R+KR++K E
Sbjct: 616 EEMVKNKLEGKDKLTPWEQFLEKKK--EKKRLKRKQKALAE 654
Score = 30.0 bits (66), Expect = 7.9
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 21/142 (14%)
Query: 518 RELYEDVYKTKNNYPKIDLDGKEALKRLQQFFKKEKDRFKIK-KTKSKENLSAFSILLPD 576
+E E++ K K L+GK+ L +QF +K+K++ ++K K K+ ++ L D
Sbjct: 612 KESAEEMVKNK-------LEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSD 664
Query: 577 LELK----SQEVIIYDDVDLSEKESKD----EDKLKMWKPK-----FLTPKEKKEKNGAE 623
++L ++EV S K +KD E+++++ + K + +++ K
Sbjct: 665 VDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFN 724
Query: 624 ESESFSPRNFFKTKKQNLEKNR 645
++ +N K KK+ L K +
Sbjct: 725 YNKIVEHQNLSKKKKKQLMKKK 746
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 42.4 bits (98), Expect = 0.002
Identities = 76/360 (21%), Positives = 126/360 (35%), Gaps = 53/360 (14%)
Query: 223 KSWENPPPERSPASSPCQPIYECELASQAP-----EKQPDVRHHHLPKTKPLP------S 271
K PPP P P P + +L Q P + QP + H P +P+ S
Sbjct: 949 KVQSQPPP---PLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFS 1005
Query: 272 IDSLGPPPPKPSRPPIVNLQAFQRQPAAVPKTQGEVTVEEGSLSPERLFNAEFEEPHNYE 331
PPPP+ +PP + Q+ P P +V S P + + H E
Sbjct: 1006 THIQQPPPPQGQQPP--HPPPGQQPPPPQPAKPQQVIQHHHS--PRHHKSDPYSTGHLRE 1061
Query: 332 ATISYLRHSGNSINLCTAKEIADPTYEVGIEELQKPGKNFPYPEPSAKHEDKKMKEK--Q 389
A + HS + + P V ++ + + P+P +++K+ +
Sbjct: 1062 APSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIR 1121
Query: 390 PCELKPKNTEKEPYSNHVFKVDACEGTPEKIQMTNVHTGRRNMLAGKQEAMIDIIQTNPC 449
P + P H + A P++ +M V GR + +Q A P
Sbjct: 1122 SEPFSPSLRPEPP--KHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNA--------PP 1171
Query: 450 PEGPKLARHSQGHCGHLEVLESTKETPDLGVSKTSSISEEIYDDVEYSRKEVPKLNYSSS 509
P P + Q E DL + S + + P SS
Sbjct: 1172 PGAPDKDKQKQ------EPKTPVAPKKDLKIKNMGS-----WASLVQKHPTTP-----SS 1215
Query: 510 LASSSEENRELYEDVYKTKNNYPKIDLDGKEALKRLQQFFKKEKDRFKIKKTKSKENLSA 569
A SS ++ E + + K K ALK + +KEK+R + ++ +S+E+ A
Sbjct: 1216 TAKSSSDSFEQFRRAAREKEEREK-------ALKAQAEHAEKEKERLRQERMRSREDEDA 1268
Score = 36.2 bits (82), Expect = 0.11
Identities = 42/149 (28%), Positives = 57/149 (38%), Gaps = 31/149 (20%)
Query: 196 SQKHVVAPKILHN-VSEDPSFVISQHIRKSWENPPPERSPASSPCQPIYECELASQAPEK 254
+Q VV+P LHN + + PS + R + P P R PA SP + + L Q P
Sbjct: 852 NQHAVVSPPALHNALPQQPSRPSN---RAAALPPKPARPPAVSPA--LTQTPLLPQPPMA 906
Query: 255 QP--------------------DVRHHHLPKTKP----LPSIDSLG-PPPPKPSRPPIVN 289
QP + L K +P LPS+ PPPP P P
Sbjct: 907 QPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSV 966
Query: 290 LQAFQRQPAAVPKTQGEVTVEEGSLSPER 318
Q Q+QP P Q + ++ P R
Sbjct: 967 QQQLQQQPPPPPPPQPQPPPQQQHQPPPR 995
Score = 31.6 bits (70), Expect = 2.7
Identities = 29/110 (26%), Positives = 43/110 (39%), Gaps = 18/110 (16%)
Query: 226 ENPPPERSPASSPCQPIYECE------LASQAPEKQPD--------VRHHHLPKTK-PLP 270
+ PPP P S P Q + +A+Q P +P + H P P P
Sbjct: 774 QQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQP 833
Query: 271 SIDSLGPPPPKPSRPPIVNLQAFQRQPA---AVPKTQGEVTVEEGSLSPE 317
+ P PP+ S PP +N A PA A+P+ + +L P+
Sbjct: 834 ELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPK 883
Score = 30.0 bits (66), Expect = 7.9
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 6/75 (8%)
Query: 233 SPASSPCQPIYECELASQAPEK------QPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPP 286
S +SS E E+A ++ +K Q HHH + + P+ PPPP PP
Sbjct: 707 SESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPP 766
Query: 287 IVNLQAFQRQPAAVP 301
Q Q+ P P
Sbjct: 767 PPPPQQQQQPPPPPP 781
Score = 30.0 bits (66), Expect = 7.9
Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 7/77 (9%)
Query: 231 ERSPASSPCQPIYECELASQAPEKQPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPPIVNL 290
+++PA P QP + Q P P + P P PS+ P K S PP +
Sbjct: 747 QQAPAPVPQQPPPPPQ---QPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIAT 803
Query: 291 QAFQRQPAAVPKTQGEV 307
Q P P+ G V
Sbjct: 804 QV----PVLEPQLPGSV 816
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 41.6 bits (96), Expect = 0.003
Identities = 121/613 (19%), Positives = 232/613 (37%), Gaps = 97/613 (15%)
Query: 52 GKP--LSSNHKQR---TPYCSSSESQPLQPQKIKLAQKSEIPKCSNSPGPLGKSTVCSAT 106
GKP ++S H+QR + SS S L+P ++K A S+ C L S S
Sbjct: 1897 GKPENVASQHEQRIAGSVQLDSSSSNELRPGQLKAAVSSKDHTCEVRKQVLPHSAEESHL 1956
Query: 107 SSQKASLLLEVTQSNVEIIT---------------KEKVMVANSFRNKLWNWEKVSSQKS 151
SSQ+A L+ + N E ++ K V+ N RN E S +S
Sbjct: 1957 SSQEAVSALDTSSGNTETLSSKSYSSEEVKLAEEPKSLVLAGNVERNIAEGKEIHSLMES 2016
Query: 152 E---MSSALLLANYGSKAIHLEGQKGMGLTPEEP-RKKLETKGAQTLPSQKHVVAPKILH 207
E + A ++ SK + Q+ + L PE +K + + + S+ + K H
Sbjct: 2017 ESLLLEKANTELSWPSKE---DSQEKIKLPPERFFQKPVSGLSVEQVKSETISSSVKTAH 2073
Query: 208 NVSEDPSFVISQHIRKSWENPP-PERSPASSPCQPIYECELASQAPE-KQPDVRHHHLPK 265
+E + PP PE P + + ++ A E K+P +
Sbjct: 2074 FPAEGVEPALGNEKEAHRSTPPFPEEKPLEE--SKMVQSKVIDDADEGKKPSPEVKIPTQ 2131
Query: 266 TKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQPAA--VPKTQGEVTVEE----------GS 313
KP+ SI + P P P + Q + A +P+ +G+ + GS
Sbjct: 2132 RKPISSIHAR--EPQSPESPEVTQNPPTQPKVAKPDLPEEKGKKGISSFKSWMSSLFFGS 2189
Query: 314 LSPERLF----NAEFEEPHNYEATISYLRHSGNSINLCTAKEIADPTYEVGIEELQKPGK 369
+P+ + E + + E ++ + G + T +A+ + + E++
Sbjct: 2190 STPDNKVAEQEDLETQPSPSVEKAVTVIDPEGT---IPTNFNVAEKPADHSLSEVKLKTA 2246
Query: 370 NFPYPEPSAKHEDKKMKEKQPCELKPKNTEKEPYSNHVFKVDACEGTPEKIQMTNVHTGR 429
+ P + + +KEK ++ ++ + + V + D G+
Sbjct: 2247 DEPRGTLVKSGDGQNVKEKSMILSNVEDLQQPKFISEVSREDY---------------GK 2291
Query: 430 RNMLAGKQEAMIDIIQTNPCPEGPKLARHSQGHCGHLEVLESTKETPDLGVSKTSSISEE 489
+ + +E I+ + T+ +G L S G V+E K V+ + + +
Sbjct: 2292 KEISGDSEEMNINSVVTSA--DGENLEIQSYSLIGEKLVMEEAKTIVPPHVTDSKRVQKP 2349
Query: 490 IYDDVEYSRKEVPKLNYSSSLASSSEENRELYEDVYKTKNNYPKIDLDGKEALKRLQQFF 549
++A S+ N ++++ + +++ + L + + ++ Q
Sbjct: 2350 -------------------AIAPPSKWNISIFKE--EPRSDQKQKSLLSFDVVDKVPQQP 2388
Query: 550 KKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYDDVDLSEKESKDEDKLKM---- 605
K F K +KE+ SI+LP E K +I D +KE ++ LK+
Sbjct: 2389 KSASSNFASKNI-TKESEKPESIILPVEESKGS--LIDFSEDRLKKEMQNPTSLKISEEE 2445
Query: 606 WKPKFLTPKEKKE 618
K + ++P EKK+
Sbjct: 2446 TKLRSVSPTEKKD 2458
>gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo
sapiens]
Length = 529
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/234 (20%), Positives = 99/234 (42%), Gaps = 34/234 (14%)
Query: 430 RNMLAGKQEAMIDIIQTNPCPEGPKLARHSQGHCGHLEVLESTKETPDLGVSKTSSISEE 489
RN GK M ++++ P ++ +H + + L + E KE+ + +K EE
Sbjct: 262 RNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREE 321
Query: 490 IYDDVEYSRKEVPKLNYSSSLASSSEENRELYEDVYKTKNNYPKIDLDGKEALKRLQQFF 549
I+ K K + + L + +E+ + ++ + K K+ ++ + K ++
Sbjct: 322 IF-------KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQ---KLAVEAWKKQKSIEMSM 371
Query: 550 K-----KEKDRFKIKKTKSKENLSAFSILLPDL--ELKSQEVIIYDDVDLSEKESKDEDK 602
K KE++ + K K ++ +LL + K QE + + ++ EK K E
Sbjct: 372 KCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAE-- 429
Query: 603 LKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRER 656
K KN A+E F R+ K + + L++ + K +EK ++R
Sbjct: 430 --------------KRKNAADEISRFQERDLHKLELKILDR-QAKEDEKSQKQR 468
>gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo
sapiens]
Length = 446
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/234 (20%), Positives = 99/234 (42%), Gaps = 34/234 (14%)
Query: 430 RNMLAGKQEAMIDIIQTNPCPEGPKLARHSQGHCGHLEVLESTKETPDLGVSKTSSISEE 489
RN GK M ++++ P ++ +H + + L + E KE+ + +K EE
Sbjct: 179 RNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREE 238
Query: 490 IYDDVEYSRKEVPKLNYSSSLASSSEENRELYEDVYKTKNNYPKIDLDGKEALKRLQQFF 549
I+ K K + + L + +E+ + ++ + K K+ ++ + K ++
Sbjct: 239 IF-------KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQ---KLAVEAWKKQKSIEMSM 288
Query: 550 K-----KEKDRFKIKKTKSKENLSAFSILLPDL--ELKSQEVIIYDDVDLSEKESKDEDK 602
K KE++ + K K ++ +LL + K QE + + ++ EK K E
Sbjct: 289 KCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAE-- 346
Query: 603 LKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRER 656
K KN A+E F R+ K + + L++ + K +EK ++R
Sbjct: 347 --------------KRKNAADEISRFQERDLHKLELKILDR-QAKEDEKSQKQR 385
>gi|22027646 angiomotin like 1 [Homo sapiens]
Length = 956
Score = 41.2 bits (95), Expect = 0.003
Identities = 72/309 (23%), Positives = 116/309 (37%), Gaps = 48/309 (15%)
Query: 228 PPPERSPASSPCQPIYECELASQAP-EKQPDVRHHHLPKTK-PLPSIDSLGPPPPKPSRP 285
PPPE S PCQ + + +P Q L PLP +LG P P P+
Sbjct: 366 PPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQPPPAAS 425
Query: 286 PIVNL--QAFQRQPAAVPKTQG--EVTVEEGSLSPERL--FNAEFEEPHNYEATISYLRH 339
P L AF A V + Q E+ EE + + L + ++ H +E + +
Sbjct: 426 PSQQLGPDAF----AIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISE 481
Query: 340 SGNSINLCTAKEIADPTYEVGIEELQKPGKNFPYPEPSAKHE-DKKMKEKQPCELKPKNT 398
+ S+ T K E L K +N E H+ ++ ++++ E +
Sbjct: 482 AYESLVKSTTKR----------ESLDKAMRNKLEGEIRRLHDFNRDLRDR--LETANRQL 529
Query: 399 EKEPYSNHVFKVDACEGTPEKIQMTNVHTGRRNMLAGKQEAMIDIIQTNPCPEGPKLARH 458
Y H K A EG H +N K++ +++ E +
Sbjct: 530 SSREYEGHEDK--AAEG----------HYASQNKEFLKEKEKLEM-------ELAAVRTA 570
Query: 459 SQGHCGHLEVLESTKETPDLGVSKTSSISEEIYDDVEYSRKEVPKLNYSSSLASSSEENR 518
S+ H H+E+L+ V K + EE+ + Y K V KL + + S+ E R
Sbjct: 571 SEDHRRHIEILDQALSNAQARVIK---LEEELREKQAYVEK-VEKLQQALTQLQSACEKR 626
Query: 519 ELYEDVYKT 527
E E +T
Sbjct: 627 EQMERRLRT 635
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 40.4 bits (93), Expect = 0.006
Identities = 85/354 (24%), Positives = 134/354 (37%), Gaps = 46/354 (12%)
Query: 68 SSESQPLQPQKIKLAQKSEIP--KCSNSPGPLGKSTVCSATSSQK----ASLLLEVTQSN 121
SS+ + QK + QK P K + +P KS+ + SS + + ++T
Sbjct: 132 SSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVT 191
Query: 122 VEIITKEKVMVANSFRNKLWNWEKVSSQKSEMSSALLLANYGSKAIHLEGQKGMGLTPEE 181
V+ TK A + K+ N + SS S SS S + E +K TP++
Sbjct: 192 VKAQTKAPPKPARA-APKIANGKAASSSSSSSSS--------SSSDDSEEEKAAA-TPKK 241
Query: 182 --PRKKLETKG---AQTLPSQKHVVAPKILHNVSEDPSFVISQHIRKSWENPPPERSPAS 236
P+K++ K A T P++K + SED S + +K +N P S
Sbjct: 242 TVPKKQVVAKAPVKAATTPTRKS--------SSSEDSSSDEEEEQKKPMKNKPGPYSSVP 293
Query: 237 SPCQPIYECELASQAPEKQPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQ 296
P P + L +Q P+K + + DS KP +V+ +
Sbjct: 294 PPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPP 353
Query: 297 PAAVPKTQGEVTVEEGSLSPERLFNAEFEEPHNYEATISYLRHSGNSINLCT----AKEI 352
PA + E S S + + + E P T ++S N + T K
Sbjct: 354 PA-------KKAAESSSDSSDSDSSEDDEAPSKPAGT---TKNSSNKPAVTTKSPAVKPA 403
Query: 353 ADPTYEVGIEE--LQKPGKNFPYPEPSAKHEDKKMKEKQPCELKPKNTEKEPYS 404
A P VG + L + + E S+ E++K K K KPK T K S
Sbjct: 404 AAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTK-KMVATTKPKATAKAALS 456
Score = 30.8 bits (68), Expect = 4.6
Identities = 63/310 (20%), Positives = 106/310 (34%), Gaps = 48/310 (15%)
Query: 25 PGP---IKFPAGVSPKGDIGGTQSTQILANGKPLSSNHKQRTPYCSSSESQPLQPQKIKL 81
PGP + P+ PK +G + + +P+ S+ SS ES ++ K
Sbjct: 286 PGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSED------SSDESDSSSEEEKKP 339
Query: 82 AQKSEIPKCSNSPGPLGKSTVCSATSSQKASLLLEVTQSNVEIITKEK------------ 129
K+ + K + P P K+ S+ SS S + S TK
Sbjct: 340 PTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPA 399
Query: 130 VMVANSFRNKLWNWEKVSSQKSEMSSALLLANYGSKAIHLEGQKGMGLTPEEPRKKLETK 189
V A + + + +K+ ++K++ SS + S + E K M T + K K
Sbjct: 400 VKPAAAPKQPVGGGQKLLTRKADSSS----SEEESSSSEEEKTKKMVAT---TKPKATAK 452
Query: 190 GAQTLPSQKHVVAPKILHNVSEDPSFVISQHIRKSWENPPPERSPASSPCQPIYECELAS 249
A +LP+++ AP+ + S D S+ + ++ P +
Sbjct: 453 AALSLPAKQ---APQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKP---------QKVAGG 500
Query: 250 QAPEKQPDVRHHHLPKTKPLPSIDS--------LGPPPPKPSRPPIVNLQAFQRQPAAVP 301
AP K + + S DS G P+P P A Q
Sbjct: 501 AAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAA 560
Query: 302 KTQGEVTVEE 311
K E E+
Sbjct: 561 KNSEEEEEEK 570
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 40.4 bits (93), Expect = 0.006
Identities = 36/146 (24%), Positives = 75/146 (51%), Gaps = 25/146 (17%)
Query: 518 RELYEDVYKTKNNYPKIDLDGKEALKRLQQFFKKEKDRF-KIKKTKSKENLSAFSILLPD 576
R YE ++ + LD K R + + +KE F K+K+ + +E+L F L
Sbjct: 555 RGRYEKIHGRSKEKERASLDKK----RDKDYRRKEILPFEKMKEQRLREHLVRFERLRRA 610
Query: 577 LELKSQEVIIYDDVDLSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKT 636
+EL+ + +++E+E ++ +++++ + +E++E+ E R +
Sbjct: 611 MELRRRR-------EIAERERRERERIRI-----IREREERERLQRE-------RERLEI 651
Query: 637 KKQNLEKNRMKREEKLFRERFKYDKE 662
++Q LE+ RM+R E+L RER + ++E
Sbjct: 652 ERQKLERERMER-ERLERERIRIEQE 676
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 40.4 bits (93), Expect = 0.006
Identities = 36/146 (24%), Positives = 75/146 (51%), Gaps = 25/146 (17%)
Query: 518 RELYEDVYKTKNNYPKIDLDGKEALKRLQQFFKKEKDRF-KIKKTKSKENLSAFSILLPD 576
R YE ++ + LD K R + + +KE F K+K+ + +E+L F L
Sbjct: 573 RGRYEKIHGRSKEKERASLDKK----RDKDYRRKEILPFEKMKEQRLREHLVRFERLRRA 628
Query: 577 LELKSQEVIIYDDVDLSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKT 636
+EL+ + +++E+E ++ +++++ + +E++E+ E R +
Sbjct: 629 MELRRRR-------EIAERERRERERIRI-----IREREERERLQRE-------RERLEI 669
Query: 637 KKQNLEKNRMKREEKLFRERFKYDKE 662
++Q LE+ RM+R E+L RER + ++E
Sbjct: 670 ERQKLERERMER-ERLERERIRIEQE 694
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 40.4 bits (93), Expect = 0.006
Identities = 43/195 (22%), Positives = 79/195 (40%), Gaps = 21/195 (10%)
Query: 473 KETPDLGVSKTSSISEEIYDDVEYSRKEVPKLNYSSSLASSSEENRELYEDVYKTKNNYP 532
K P K + E+ + + + SS ++SS E + + + +P
Sbjct: 254 KSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFP 313
Query: 533 KIDLDGKEALKRL-QQFFKKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYDDVD 591
L+R+ ++F K ++ K++ + +E L L + E K + +
Sbjct: 314 T-----STPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEK-------LK 361
Query: 592 LSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFKTKKQN--------LEK 643
K +K+E K K + K L KE++EK +E E + + +++ LE+
Sbjct: 362 EEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEE 421
Query: 644 NRMKREEKLFRERFK 658
R K EEK RE K
Sbjct: 422 KRKKEEEKRLREEEK 436
>gi|38570058 hypothetical protein LOC80129 [Homo sapiens]
Length = 715
Score = 40.0 bits (92), Expect = 0.008
Identities = 42/208 (20%), Positives = 90/208 (43%), Gaps = 17/208 (8%)
Query: 469 LESTKETPDLGVSKTSSISEEIYD-DVEYSRKEVPKLNYSSSLASSSEENRELYEDVYKT 527
+ES KE S +S+ + + + + E + K+ + ++ +EN+EL + V +
Sbjct: 84 MESYKENNARKSSLLTSLRDRVQELEEESAALSTSKIRTEITAHAAIKENQELKKKVVEL 143
Query: 528 KNNYPKIDLDGKEALKRL-------QQFFKKEKDRFKIKKTKSKENLSAFSILLPDLE-- 578
K + +E K++ ++F + +D + K + + L DL
Sbjct: 144 NEKLQKCSKENEENKKQVSKNCRKHEEFLTQLRDCLDPDERNDKASDEDLILKLRDLRKE 203
Query: 579 ---LKSQEVIIYDDVDLSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEESESFSPRNFFK 635
+K Q VI+ + +++ E E+K + M + ++KK + EE E +
Sbjct: 204 NEFVKGQIVILEETINVHEMEAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSA 263
Query: 636 TKKQNLEKNRMKREEKLFRERFKYDKEI 663
+ K ++RE K+F+ER +++
Sbjct: 264 VE----AKEALEREVKIFQERLLAGQQV 287
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 40.0 bits (92), Expect = 0.008
Identities = 45/208 (21%), Positives = 89/208 (42%), Gaps = 21/208 (10%)
Query: 467 EVLESTKETPDLGVSKTSSISEEIYDDVEYSRKEVPKL----------NYSSSLASSSEE 516
E+ E P L +S+ E++ D+ ++ R+EV L N + SL S ++
Sbjct: 277 ELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQK 336
Query: 517 NR-----ELYEDVYKTKNNYPKIDLDGKEALKRLQQFFKKEKDRFKIKKTKSKENLSAFS 571
R E+ + + + + E L+ Q+ +++ +R ++K + +
Sbjct: 337 QRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGER--LRKQEQRLRKQEER 394
Query: 572 ILLPDLELKSQEVIIYDDVDLSEKESKDEDKLKMWKPKF-LTPKEKKEKNGAEESESFSP 630
+ + L+ QE ++D E+ K E++L+ + + L+ K +K AE SF
Sbjct: 395 LRKEEERLQKQEKRLWDQ---EERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFED 451
Query: 631 RNFFKTKKQNLEKNRMKREEKLFRERFK 658
N K LE+ + +EKL E +
Sbjct: 452 LNNEKKSALQLEQQVKELQEKLDEEHLE 479
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 40.0 bits (92), Expect = 0.008
Identities = 45/208 (21%), Positives = 89/208 (42%), Gaps = 21/208 (10%)
Query: 467 EVLESTKETPDLGVSKTSSISEEIYDDVEYSRKEVPKL----------NYSSSLASSSEE 516
E+ E P L +S+ E++ D+ ++ R+EV L N + SL S ++
Sbjct: 277 ELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQK 336
Query: 517 NR-----ELYEDVYKTKNNYPKIDLDGKEALKRLQQFFKKEKDRFKIKKTKSKENLSAFS 571
R E+ + + + + E L+ Q+ +++ +R ++K + +
Sbjct: 337 QRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGER--LRKQEQRLRKQEER 394
Query: 572 ILLPDLELKSQEVIIYDDVDLSEKESKDEDKLKMWKPKF-LTPKEKKEKNGAEESESFSP 630
+ + L+ QE ++D E+ K E++L+ + + L+ K +K AE SF
Sbjct: 395 LRKEEERLQKQEKRLWDQ---EERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFED 451
Query: 631 RNFFKTKKQNLEKNRMKREEKLFRERFK 658
N K LE+ + +EKL E +
Sbjct: 452 LNNEKKSALQLEQQVKELQEKLDEEHLE 479
>gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]
Length = 860
Score = 40.0 bits (92), Expect = 0.008
Identities = 40/166 (24%), Positives = 76/166 (45%), Gaps = 21/166 (12%)
Query: 498 RKEVPKLNYSSSLASSSEENRELYEDVYKTKNNYPKIDLDGKEALKRLQQFFKKEKDRFK 557
RK++ +L+ ++ + ++ ++ + E K D K+ K+L+Q +K D K
Sbjct: 119 RKDIQRLSLNNDIFEANSDSDQQSET---------KEDTSPKKKKKKLRQREEKSPDDLK 169
Query: 558 IKKTK-------SKENL-SAFSILLPDLELKSQEVIIYDDVDLSEKESKDEDKLKMWKPK 609
KK K SK +L S+ L+ DL K + +++ S+K KDE K + K
Sbjct: 170 KKKAKAGKLKDKSKPDLESSLESLVFDLRTKKRISEAKEELKESKKPKKDEVK----ETK 225
Query: 610 FLTPKEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRE 655
L +K E + P+ KTKK+ +++++ E + +
Sbjct: 226 ELKKVKKGEIRDLKTKTREDPKENRKTKKEKFVESQVESESSVLND 271
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 40.0 bits (92), Expect = 0.008
Identities = 45/208 (21%), Positives = 89/208 (42%), Gaps = 21/208 (10%)
Query: 467 EVLESTKETPDLGVSKTSSISEEIYDDVEYSRKEVPKL----------NYSSSLASSSEE 516
E+ E P L +S+ E++ D+ ++ R+EV L N + SL S ++
Sbjct: 277 ELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQK 336
Query: 517 NR-----ELYEDVYKTKNNYPKIDLDGKEALKRLQQFFKKEKDRFKIKKTKSKENLSAFS 571
R E+ + + + + E L+ Q+ +++ +R ++K + +
Sbjct: 337 QRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGER--LRKQEQRLRKQEER 394
Query: 572 ILLPDLELKSQEVIIYDDVDLSEKESKDEDKLKMWKPKF-LTPKEKKEKNGAEESESFSP 630
+ + L+ QE ++D E+ K E++L+ + + L+ K +K AE SF
Sbjct: 395 LRKEEERLQKQEKRLWDQ---EERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFED 451
Query: 631 RNFFKTKKQNLEKNRMKREEKLFRERFK 658
N K LE+ + +EKL E +
Sbjct: 452 LNNEKKSALQLEQQVKELQEKLDEEHLE 479
>gi|239047795 pleckstrin homology domain containing, family A member
7 [Homo sapiens]
Length = 1121
Score = 39.7 bits (91), Expect = 0.010
Identities = 32/90 (35%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 224 SWENPPPERSPASSPCQPIYECELASQAPEKQPDVRHH-HLPK-TKPLPSIDSLGPP--P 279
S PPP+ SP +SP + E L Q P H L K T PL S P
Sbjct: 858 SESKPPPQPSPPTSPVRTPLEVRLFPQLQTYVPYRPHPPQLRKVTSPLQSPTKAKPKVED 917
Query: 280 PKPSRPPIVNLQAFQRQPAAVPKTQGEVTV 309
P RPP+ L + + QP AVP E T+
Sbjct: 918 EAPPRPPLPELYSPEDQPPAVPPLPREATI 947
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 39.7 bits (91), Expect = 0.010
Identities = 35/180 (19%), Positives = 77/180 (42%), Gaps = 25/180 (13%)
Query: 482 KTSSISEEIYDDVEYSRKEVPKLNYSSSLASSSEENRELYEDVYKTKNNYPKIDLDGKEA 541
K E+I + E R++ K+ + EE E++ K +E
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK----------EEK 364
Query: 542 LKRLQQFFKKEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYDDVDLSEKESKDED 601
++RL++ +++++ + + K E +++ QE ++ + E+E + E
Sbjct: 365 MRRLEEMMWEKEEKIRELEEKMHEQE----------KIREQEEKRQEEEKIREQEKRQEQ 414
Query: 602 KLKMWK--PKFLTPKEK---KEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRER 656
+ KMW+ K +EK +EK + E + + +++ E+ M R+E+ RE+
Sbjct: 415 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 474
Score = 32.0 bits (71), Expect = 2.1
Identities = 37/166 (22%), Positives = 78/166 (46%), Gaps = 28/166 (16%)
Query: 515 EENRELYEDVYKTKNNYPKIDLDGKEALKRL--------QQFFKKEKDRFKIKKTKSKEN 566
E+N +L E + ++ +I L+ KE ++L QQ + E D K ++
Sbjct: 221 EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG----KELQS 276
Query: 567 LSAFSILLPDLELKSQEVIIYDDVDLSEKES--KDEDKLKMWKPKFLTPKEK----KEKN 620
+SA L+ + +E +++ ++ ++E + E+K++ W+ K +EK +EK
Sbjct: 277 VSA------KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 621 GAEESESFSPRNFFKTKKQNL---EKNRMKREEKLFR-ERFKYDKE 662
+E + K++ + E+ ++EEK+ R E ++KE
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE 376
>gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]
Length = 498
Score = 39.3 bits (90), Expect = 0.013
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 17/105 (16%)
Query: 182 PRKKLETKGAQTLPSQKHVVAPKILHNVSEDPSFVIS---QHIRKSWENPPPERSPASSP 238
P KK +T+ ++ K VV P ++ + E + RKS E+ P RS +
Sbjct: 314 PIKKRKTRETVSI-EVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSS--- 369
Query: 239 CQPIYECELASQAPEKQPDVRHHHLPKTK-PLPSIDSLGPPPPKP 282
AS P+K+ HHH K P+P + L PPPP+P
Sbjct: 370 ---------ASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEP 405
>gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]
Length = 486
Score = 39.3 bits (90), Expect = 0.013
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 17/105 (16%)
Query: 182 PRKKLETKGAQTLPSQKHVVAPKILHNVSEDPSFVIS---QHIRKSWENPPPERSPASSP 238
P KK +T+ ++ K VV P ++ + E + RKS E+ P RS +
Sbjct: 302 PIKKRKTRETVSI-EVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSS--- 357
Query: 239 CQPIYECELASQAPEKQPDVRHHHLPKTK-PLPSIDSLGPPPPKP 282
AS P+K+ HHH K P+P + L PPPP+P
Sbjct: 358 ---------ASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEP 393
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 39.3 bits (90), Expect = 0.013
Identities = 33/112 (29%), Positives = 53/112 (47%), Gaps = 7/112 (6%)
Query: 179 PEEPRKKLETKGAQTLPSQKHVVAPKILHNVSED--PSFVISQHIRKSWENPPPERSPAS 236
PE P++ + K P +K V P + V + P + + I E+PPPE A
Sbjct: 10526 PEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEA- 10584
Query: 237 SPCQPIYECELASQAPEKQPDVRHHHLPKT--KPLPSIDSLGPPPPKPSRPP 286
P + + E ++ + AP K+P+V +P+ + +P PPP KP PP
Sbjct: 10585 -PKEVVPEKKVPA-APPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPP 10634
Score = 38.5 bits (88), Expect = 0.022
Identities = 86/420 (20%), Positives = 155/420 (36%), Gaps = 50/420 (11%)
Query: 10 KELRAKFQNLDAPPLPGPIKFPA-----GVSPKGDIGGTQSTQILANGKPLSSNHKQRTP 64
+++ AK APP P IK P S + + Q T++ K + RTP
Sbjct: 9163 RKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTP 9222
Query: 65 YCSSSESQPLQPQKIKLAQKSEIPKCSNSPGPLGKSTVCSATSSQKASLLLEVTQSNVEI 124
+Q + I++ ++P + + + A+ +++ + + V + EI
Sbjct: 9223 ---------VQEEVIEV----KVPAVHTKKMVISEEKMFFASHTEE-EVSVTVPEVQKEI 9268
Query: 125 ITKEKVMVANSFRNKLWNWEKVSSQKSEMSSALLLANYGSKAIHLEGQKGMGLTPEEPRK 184
+T+EK+ VA S R + + E+ I + + PE P+K
Sbjct: 9269 VTEEKIHVAISKR------VEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKK 9322
Query: 185 KL-ETKGAQTLPSQKHVVAPKILHNVSED-PSFVISQHIRKSWENPPPERSPASSPCQPI 242
+ E K +P ++ PK+ + P I + K E PP +
Sbjct: 9323 PVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTE 9382
Query: 243 YECELASQAPEKQP----DVRHHHLPKT-KPLPSIDSLGPPPPK-PSRP--PIVNLQAFQ 294
+ + +Q E P ++ +P+ KP+P + PPPPK P+ P P+ +
Sbjct: 9383 EKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAV 9442
Query: 295 RQPAAVPKTQGEVTVEEGSLSPERLFNAE----FEEPHNYEATISYL----------RHS 340
P A V + ++ E+ F AE F P E T +
Sbjct: 9443 PVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEE 9502
Query: 341 GNSINLCTAKEIADPTYEVGIEELQKPGKNFPYPEPSAKHEDKKMKEKQPCELKPKNTEK 400
G SI++ +E + E + E + + Y H K E +P E+ + +K
Sbjct: 9503 GVSISVYREEE-REEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKK 9561
Score = 35.4 bits (80), Expect = 0.19
Identities = 54/232 (23%), Positives = 87/232 (37%), Gaps = 23/232 (9%)
Query: 179 PEEPRKK-LETKGAQTLPSQKHVVAPKILHNVSE-DPSFVISQHIRKSW---ENPPPERS 233
PE P+K LE K A +P + P++ E P I+ K E PE
Sbjct: 10776 PEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVP 10835
Query: 234 PASSPCQPIYECELASQAPEKQPDVRHHHLPKTKPLPSIDSLGP-PPPKPSRPPIVNLQA 292
P + P +P K+P+ P+ + + L P PPP P PP +++
Sbjct: 10836 PPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKE 10895
Query: 293 FQRQPAAVPKTQGEVTVEEGSLSPERLFNAEFEEPHNYEATISYLRHSGNSINLCTAKEI 352
Q A+PK + V E PE++ E T + + +
Sbjct: 10896 KIFQLKAIPKKK----VPEKPQVPEKV-----------ELTPLKVPGGEKKVRKLLPERK 10940
Query: 353 ADPTYEVGIEEL--QKPGKNFPYPEPSAKHEDKKMKEKQPCELKPKNTEKEP 402
+P EV ++ + ++P + P EP + KK +P KP + P
Sbjct: 10941 PEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVP 10992
Score = 33.1 bits (74), Expect = 0.94
Identities = 42/162 (25%), Positives = 62/162 (38%), Gaps = 28/162 (17%)
Query: 179 PEEPRKKLETKGAQTL--PSQKHVVAPKILHNVSEDPSFVISQHIRKSWENPPPERSPAS 236
PEE K+E K + + P+ PK + V E P+ +++ RK P P + P
Sbjct: 10957 PEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV-EVPT--VTKRERKI---PEPTKVPEI 11010
Query: 237 SPCQPIYECELASQAPEKQPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQ 296
P P+ APE PK KP + ++ PPP +P PI A
Sbjct: 11011 KPAIPL-------PAPE----------PKPKPEAEVKTIKPPPVEPEPTPIA---APVTV 11050
Query: 297 PAAVPKTQGEVTVEEGSLSPERLFNAEFEEPHNYEATISYLR 338
P K + + EE + + + P EA LR
Sbjct: 11051 PVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLR 11092
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 39.3 bits (90), Expect = 0.013
Identities = 42/172 (24%), Positives = 71/172 (41%), Gaps = 10/172 (5%)
Query: 497 SRKEVPKLNYSSSLASSSEENRELYEDVYKTKNNYPKIDLDG------KEALKRLQQFFK 550
+RKE K S E + E + K K + G +E KR ++
Sbjct: 47 TRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKEN 106
Query: 551 KEKDRFKIKKTKSKENLSAFSILLPDLELKSQEVIIYDDVDLSEKESKDEDKLKMWKPKF 610
KE + + +K K K+ S + E K + + E+E K E++ K + K
Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKEER----KREERKERERKKEEREKERERKE 162
Query: 611 LTPKEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRERFKYDKE 662
+E+K+ EE R K +++N ++ + +RE K RER K K+
Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Score = 36.2 bits (82), Expect = 0.11
Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 15/149 (10%)
Query: 514 SEENRELYEDVYKTKNNYPKIDLDGKEALKRLQQFFKKEKDRFKIKKTKSKENLSAFSIL 573
++E E + K K + +GKE ++ ++ ++ K+R + K+ + KE
Sbjct: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER------- 158
Query: 574 LPDLELKSQEVIIYDDVDLSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEESESFSPRNF 633
E K ++ V E+E K++++ + K + + KKE+ E E R
Sbjct: 159 ----ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK- 213
Query: 634 FKTKKQNLEKNRMKREEKLFRERFKYDKE 662
KK+ +K R K + +RE+ + +E
Sbjct: 214 ---KKEERKKERQKDRQTNWREKERGKRE 239
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,975,248
Number of Sequences: 37866
Number of extensions: 1840973
Number of successful extensions: 10250
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 427
Number of HSP's that attempted gapping in prelim test: 8640
Number of HSP's gapped (non-prelim): 1643
length of query: 728
length of database: 18,247,518
effective HSP length: 110
effective length of query: 618
effective length of database: 14,082,258
effective search space: 8702835444
effective search space used: 8702835444
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.