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Search of human proteins with 166706903
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|166706903 guanylate binding protein 1, interferon-inducible,
67kDa [Homo sapiens]
(592 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|166706903 guanylate binding protein 1, interferon-inducible, ... 1167 0.0
gi|112382372 guanylate binding protein 3 [Homo sapiens] 1022 0.0
gi|38327558 guanylate binding protein 2, interferon-inducible [H... 915 0.0
gi|197333737 guanylate-binding protein 5 [Homo sapiens] 774 0.0
gi|16418425 guanylate-binding protein 5 [Homo sapiens] 774 0.0
gi|148234215 guanylate binding protein 4-like [Homo sapiens] 649 0.0
gi|31377634 guanylate binding protein 4 [Homo sapiens] 647 0.0
gi|157671915 guanylate binding protein family, member 6 [Homo sa... 627 e-180
gi|45827806 atlastin 3 [Homo sapiens] 75 1e-13
gi|169160863 PREDICTED: similar to guanylate-binding protein 5 [... 70 7e-12
gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens] 66 1e-10
gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens] 66 1e-10
gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens] 66 1e-10
gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens] 63 9e-10
gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens] 63 9e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 61 3e-09
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 55 2e-07
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 55 2e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 54 3e-07
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 54 3e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 54 3e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 54 4e-07
gi|118498362 kinectin 1 isoform b [Homo sapiens] 54 5e-07
gi|38044112 restin isoform b [Homo sapiens] 54 5e-07
gi|4506751 restin isoform a [Homo sapiens] 54 5e-07
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 54 5e-07
gi|45505178 cancer antigen 1 [Homo sapiens] 52 1e-06
gi|118498356 kinectin 1 isoform a [Homo sapiens] 52 2e-06
gi|118498368 kinectin 1 isoform c [Homo sapiens] 52 2e-06
gi|33620775 kinectin 1 isoform a [Homo sapiens] 52 2e-06
>gi|166706903 guanylate binding protein 1, interferon-inducible,
67kDa [Homo sapiens]
Length = 592
Score = 1167 bits (3019), Expect = 0.0
Identities = 592/592 (100%), Positives = 592/592 (100%)
Query: 1 MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAG 60
MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAG
Sbjct: 1 MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAG 60
Query: 61 KKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV 120
KKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV
Sbjct: 61 KKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV 120
Query: 121 LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVW 180
LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVW
Sbjct: 121 LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVW 180
Query: 181 TLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR 240
TLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR
Sbjct: 181 TLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR 240
Query: 241 PVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTY 300
PVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTY
Sbjct: 241 PVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTY 300
Query: 301 VNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDS 360
VNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDS
Sbjct: 301 VNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDS 360
Query: 361 EREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEE 420
EREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEE
Sbjct: 361 EREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEE 420
Query: 421 EVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQ 480
EVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQ
Sbjct: 421 EVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQ 480
Query: 481 TLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV 540
TLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV
Sbjct: 481 TLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV 540
Query: 541 QLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKACTIS 592
QLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKACTIS
Sbjct: 541 QLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKACTIS 592
>gi|112382372 guanylate binding protein 3 [Homo sapiens]
Length = 595
Score = 1022 bits (2642), Expect = 0.0
Identities = 514/586 (87%), Positives = 551/586 (94%), Gaps = 2/586 (0%)
Query: 1 MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAG 60
MA EIHMTGPMCLIENTNG L+ANPEALKILSAITQP+VVVAIVGLYRTGKSYLMNKLAG
Sbjct: 1 MAPEIHMTGPMCLIENTNGELVANPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAG 60
Query: 61 KKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV 120
K KGFSLGSTV+SHTKGIWMWCVPHPKKP H LVLLDTEGLGDV+KGDNQNDSWIF LAV
Sbjct: 61 KNKGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAV 120
Query: 121 LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVW 180
LLSST VYNS+GTINQQAMDQLYYVTELTHRIRSKSSPDENENE DSADFVSFFPDFVW
Sbjct: 121 LLSSTLVYNSMGTINQQAMDQLYYVTELTHRIRSKSSPDENENE--DSADFVSFFPDFVW 178
Query: 181 TLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR 240
TLRDFSLDLEADGQPLTPDEYL YSLKL +GTSQKD+ FNLPRLCIRKFFPKKKCFVFD
Sbjct: 179 TLRDFSLDLEADGQPLTPDEYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDL 238
Query: 241 PVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTY 300
P+HRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGI+VNGPRLESLVLTY
Sbjct: 239 PIHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTY 298
Query: 301 VNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDS 360
+NAIS GDLPCMENAVLALAQIENSAAVQKAIAHY+QQMGQKVQLP ETLQELLDLHR S
Sbjct: 299 INAISRGDLPCMENAVLALAQIENSAAVQKAIAHYDQQMGQKVQLPAETLQELLDLHRVS 358
Query: 361 EREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEE 420
EREA EV++++SFKDVDHLFQK+LAAQL+KKRDDFCKQNQEASSDRCSALLQVIFSPLEE
Sbjct: 359 EREATEVYMKNSFKDVDHLFQKKLAAQLDKKRDDFCKQNQEASSDRCSALLQVIFSPLEE 418
Query: 421 EVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQ 480
EVKAGIYSKPGGY LF+QKLQDL+KKYYEEPRKGIQAEEILQTYLKSKES+TDAILQTDQ
Sbjct: 419 EVKAGIYSKPGGYCLFIQKLQDLEKKYYEEPRKGIQAEEILQTYLKSKESVTDAILQTDQ 478
Query: 481 TLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV 540
LTEKEKEIEVE VKAESAQASAKM++EMQ K +QMME+KE+SYQEH+KQLTEKME +R
Sbjct: 479 ILTEKEKEIEVECVKAESAQASAKMVEEMQIKYQQMMEEKEKSYQEHVKQLTEKMERERA 538
Query: 541 QLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRR 586
QLL+EQE+TL KLQEQ ++LKE Q ES ++NEIQ LQ ++++
Sbjct: 539 QLLEEQEKTLTSKLQEQARVLKERCQGESTQLQNEIQKLQKTLKKK 584
>gi|38327558 guanylate binding protein 2, interferon-inducible [Homo
sapiens]
Length = 591
Score = 915 bits (2364), Expect = 0.0
Identities = 448/584 (76%), Positives = 525/584 (89%), Gaps = 2/584 (0%)
Query: 1 MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAG 60
MA EI++ GPM LI+NT G+L+ NPEALKILSAITQP+VVVAIVGLYRTGKSYLMNKLAG
Sbjct: 1 MAPEINLPGPMSLIDNTKGQLVVNPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAG 60
Query: 61 KKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV 120
KK GFSLGSTV+SHTKGIWMWCVPHPKKP H LVLLDTEGLGD+EKGDN+NDSWIFALA+
Sbjct: 61 KKNGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAI 120
Query: 121 LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVW 180
LLSSTFVYNS+GTINQQAMDQL+YVTELT RI++ SSP N V+DSADFVSFFP FVW
Sbjct: 121 LLSSTFVYNSMGTINQQAMDQLHYVTELTDRIKANSSP--GNNSVDDSADFVSFFPAFVW 178
Query: 181 TLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR 240
TLRDF+L+LE DG+P+T D+YL SLKL+KGT +K ++FN PRLCIRKFFPK+KCFVFD
Sbjct: 179 TLRDFTLELEVDGEPITADDYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKRKCFVFDW 238
Query: 241 PVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTY 300
P ++ LA LE+L++EEL+P+F++QVA+FCSYI S+S KTLSGGI VNGPRLESLVLTY
Sbjct: 239 PAPKKYLAHLEQLKEEELNPDFIEQVAEFCSYILSHSNVKTLSGGIPVNGPRLESLVLTY 298
Query: 301 VNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDS 360
VNAISSGDLPCMENAVLALAQIENSAAV+KAIAHYEQQMGQKVQLPTETLQELLDLHRDS
Sbjct: 299 VNAISSGDLPCMENAVLALAQIENSAAVEKAIAHYEQQMGQKVQLPTETLQELLDLHRDS 358
Query: 361 EREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEE 420
EREAIEVF+++SFKDVD +FQ++L AQLE +RDDFCKQN +ASSD C ALLQ IF PLEE
Sbjct: 359 EREAIEVFMKNSFKDVDQMFQRKLGAQLEARRDDFCKQNSKASSDCCMALLQDIFGPLEE 418
Query: 421 EVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQ 480
+VK G +SKPGGYRLF QKLQ+LK KYY+ PRKGIQA+E+L+ YL+SKE + DA+LQTDQ
Sbjct: 419 DVKQGTFSKPGGYRLFTQKLQELKNKYYQVPRKGIQAKEVLKKYLESKEDVADALLQTDQ 478
Query: 481 TLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV 540
+L+EKEK IEVER+KAESA+A+ KML+E+Q+KNE+MMEQKE+SYQEH+KQLTEKME DR
Sbjct: 479 SLSEKEKAIEVERIKAESAEAAKKMLEEIQKKNEEMMEQKEKSYQEHVKQLTEKMERDRA 538
Query: 541 QLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMR 584
QL+ EQE+TLALKLQEQE+LLKEGF+ ES+ ++ +I D+Q + +
Sbjct: 539 QLMAEQEKTLALKLQEQERLLKEGFENESKRLQKDIWDIQMRSK 582
>gi|197333737 guanylate-binding protein 5 [Homo sapiens]
Length = 586
Score = 774 bits (1999), Expect = 0.0
Identities = 396/591 (67%), Positives = 474/591 (80%), Gaps = 6/591 (1%)
Query: 1 MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAG 60
MA EIHM+ PMCLIEN N +L N EAL+ILSAITQP+VVVAIVGLYRTGKSYLMNKLAG
Sbjct: 1 MALEIHMSDPMCLIENFNEQLKVNQEALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAG 60
Query: 61 KKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV 120
K KGFS+ STVQSHTKGIW+WCVPHP P H LVLLDTEGLGDVEK DN+ND IFALA+
Sbjct: 61 KNKGFSVASTVQSHTKGIWIWCVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALAL 120
Query: 121 LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVW 180
LLSSTFVYN++ I+Q A+D L+ VTELT +++++SPD + VED AD SFFPD VW
Sbjct: 121 LLSSTFVYNTVNKIDQGAIDLLHNVTELTDLLKARNSPDLDR--VEDPADSASFFPDLVW 178
Query: 181 TLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR 240
TLRDF L LE DGQ +TPDEYL SL+ K+G+ Q+ + FNLPRLCI+KFFPKKKCF+FD
Sbjct: 179 TLRDFCLGLEIDGQLVTPDEYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDL 238
Query: 241 PVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTY 300
P H++KLAQLE L D+EL+PEFVQQV +FCSYIFS+S TKTL GGI VNG RL++LVLTY
Sbjct: 239 PAHQKKLAQLETLPDDELEPEFVQQVTEFCSYIFSHSMTKTLPGGIMVNGSRLKNLVLTY 298
Query: 301 VNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDS 360
VNAISSGDLPC+ENAVLALAQ ENSAAVQKAIAHY+QQMGQKVQLP ETLQELLDLHR S
Sbjct: 299 VNAISSGDLPCIENAVLALAQRENSAAVQKAIAHYDQQMGQKVQLPMETLQELLDLHRTS 358
Query: 361 EREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEE 420
EREAIEVF+++SFKDVD FQKEL L+ K++D CK+N EASSD CSALL+ IF PLEE
Sbjct: 359 EREAIEVFMKNSFKDVDQSFQKELETLLDAKQNDICKRNLEASSDYCSALLKDIFGPLEE 418
Query: 421 EVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQ 480
VK GIYSKPGG+ LF+QK ++LK KYY EPRKGIQAEE+LQ YLKSKES++ AILQTDQ
Sbjct: 419 AVKQGIYSKPGGHNLFIQKTEELKAKYYREPRKGIQAEEVLQKYLKSKESVSHAILQTDQ 478
Query: 481 TLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV 540
LTE EK+ + +VKAE+ +A A+ L +QR+NEQMM+++ER +QE ++Q ME +
Sbjct: 479 ALTETEKKKKEAQVKAEAEKAEAQRLAAIQRQNEQMMQERERLHQEQVRQ----MEIAKQ 534
Query: 541 QLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKACTI 591
L EQ++ ++QEQ L FQ ++R + +E+Q Q + C +
Sbjct: 535 NWLAEQQKMQEQQMQEQAAQLSTTFQAQNRSLLSELQHAQRTVNNDDPCVL 585
>gi|16418425 guanylate-binding protein 5 [Homo sapiens]
Length = 586
Score = 774 bits (1999), Expect = 0.0
Identities = 396/591 (67%), Positives = 474/591 (80%), Gaps = 6/591 (1%)
Query: 1 MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAG 60
MA EIHM+ PMCLIEN N +L N EAL+ILSAITQP+VVVAIVGLYRTGKSYLMNKLAG
Sbjct: 1 MALEIHMSDPMCLIENFNEQLKVNQEALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAG 60
Query: 61 KKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV 120
K KGFS+ STVQSHTKGIW+WCVPHP P H LVLLDTEGLGDVEK DN+ND IFALA+
Sbjct: 61 KNKGFSVASTVQSHTKGIWIWCVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALAL 120
Query: 121 LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVW 180
LLSSTFVYN++ I+Q A+D L+ VTELT +++++SPD + VED AD SFFPD VW
Sbjct: 121 LLSSTFVYNTVNKIDQGAIDLLHNVTELTDLLKARNSPDLDR--VEDPADSASFFPDLVW 178
Query: 181 TLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR 240
TLRDF L LE DGQ +TPDEYL SL+ K+G+ Q+ + FNLPRLCI+KFFPKKKCF+FD
Sbjct: 179 TLRDFCLGLEIDGQLVTPDEYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDL 238
Query: 241 PVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTY 300
P H++KLAQLE L D+EL+PEFVQQV +FCSYIFS+S TKTL GGI VNG RL++LVLTY
Sbjct: 239 PAHQKKLAQLETLPDDELEPEFVQQVTEFCSYIFSHSMTKTLPGGIMVNGSRLKNLVLTY 298
Query: 301 VNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDS 360
VNAISSGDLPC+ENAVLALAQ ENSAAVQKAIAHY+QQMGQKVQLP ETLQELLDLHR S
Sbjct: 299 VNAISSGDLPCIENAVLALAQRENSAAVQKAIAHYDQQMGQKVQLPMETLQELLDLHRTS 358
Query: 361 EREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEE 420
EREAIEVF+++SFKDVD FQKEL L+ K++D CK+N EASSD CSALL+ IF PLEE
Sbjct: 359 EREAIEVFMKNSFKDVDQSFQKELETLLDAKQNDICKRNLEASSDYCSALLKDIFGPLEE 418
Query: 421 EVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQ 480
VK GIYSKPGG+ LF+QK ++LK KYY EPRKGIQAEE+LQ YLKSKES++ AILQTDQ
Sbjct: 419 AVKQGIYSKPGGHNLFIQKTEELKAKYYREPRKGIQAEEVLQKYLKSKESVSHAILQTDQ 478
Query: 481 TLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV 540
LTE EK+ + +VKAE+ +A A+ L +QR+NEQMM+++ER +QE ++Q ME +
Sbjct: 479 ALTETEKKKKEAQVKAEAEKAEAQRLAAIQRQNEQMMQERERLHQEQVRQ----MEIAKQ 534
Query: 541 QLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKACTI 591
L EQ++ ++QEQ L FQ ++R + +E+Q Q + C +
Sbjct: 535 NWLAEQQKMQEQQMQEQAAQLSTTFQAQNRSLLSELQHAQRTVNNDDPCVL 585
>gi|148234215 guanylate binding protein 4-like [Homo sapiens]
Length = 638
Score = 649 bits (1673), Expect = 0.0
Identities = 324/584 (55%), Positives = 440/584 (75%), Gaps = 3/584 (0%)
Query: 1 MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAG 60
MASEIHM GP+CL ENT G L+ N EAL+ILSAITQP+VVVAIVGLYRTGKSYLMNKLAG
Sbjct: 1 MASEIHMPGPVCLTENTKGHLVVNSEALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAG 60
Query: 61 KKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV 120
K KGF LG TV+S TKGIWMWCVPHP KP H L+LLDTEGLGD+EK D ++DSWIFALAV
Sbjct: 61 KNKGFPLGCTVKSETKGIWMWCVPHPSKPNHTLILLDTEGLGDMEKSDPKSDSWIFALAV 120
Query: 121 LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVW 180
LLSS+FVYNS+GTIN QA++QL+YVTELT IR+KS P +EVEDS++FVSFFPDF+W
Sbjct: 121 LLSSSFVYNSMGTINHQALEQLHYVTELTELIRAKSCP--RPDEVEDSSEFVSFFPDFIW 178
Query: 181 TLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR 240
T+RDF+L+L+ DG P+T DEYL +LKL G + + + N PR IR FFPK+KCFVFDR
Sbjct: 179 TVRDFTLELKLDGHPITEDEYLENALKLISGKNPQIQNSNKPREWIRHFFPKQKCFVFDR 238
Query: 241 PVHRRKLA-QLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLT 299
P++ +KL +E++++++LD F Q +FCSYIF+++KTKTL GI V G RL LV T
Sbjct: 239 PINDKKLLLHVEEVREDQLDSNFQMQSENFCSYIFTHAKTKTLREGILVTGNRLGMLVET 298
Query: 300 YVNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRD 359
Y++AI+SG PC+ENA+ LAQ ENSAAVQ+A HY QQM Q+V+ PT+TLQELLD+H
Sbjct: 299 YLDAINSGATPCLENAMAVLAQCENSAAVQRAANHYSQQMAQQVRFPTDTLQELLDVHAV 358
Query: 360 SEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLE 419
EREAI VF+ SFKD FQK+L +EKK++DF QN+EAS+ C A L+ + L
Sbjct: 359 CEREAIAVFMEYSFKDKSQEFQKKLVDTMEKKKEDFVLQNEEASAKYCQAELKRLSELLT 418
Query: 420 EEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTD 479
E + G + PGG+ ++++ + +++ Y PRKG++A+E+LQ++L+S+ + ++ILQ+D
Sbjct: 419 ESISRGTFFVPGGHNIYLEAKKKIEQDYTLVPRKGVKADEVLQSFLQSQVVIEESILQSD 478
Query: 480 QTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDR 539
+ LT EK I ++ K E+A+ ++L++ Q++ +QMME +ERS+QE++ QL +KME +R
Sbjct: 479 KALTAGEKAIAAKQAKKEAAEKEQELLRQKQKEQQQMMEAQERSFQENIAQLKKKMERER 538
Query: 540 VQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKM 583
++E + L+ K++ E+LL EGF++ + EI L+ ++
Sbjct: 539 ENYMRELRKMLSHKMKVLEELLTEGFKEIFESLNEEINRLKEQI 582
>gi|31377634 guanylate binding protein 4 [Homo sapiens]
Length = 640
Score = 647 bits (1668), Expect = 0.0
Identities = 325/586 (55%), Positives = 437/586 (74%), Gaps = 3/586 (0%)
Query: 3 SEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAGKK 62
SE M P+CL+EN +L N +AL+IL I+QP+VVVAIVGLYRTGKSYLMN+LAGK+
Sbjct: 18 SESIMMAPICLVENQEEQLTVNSKALEILDKISQPVVVVAIVGLYRTGKSYLMNRLAGKR 77
Query: 63 KGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLL 122
GF LGSTVQS TKGIWMWCVPH KP H LVLLDTEGLGDVEK + +NDSWIFALAVLL
Sbjct: 78 NGFPLGSTVQSETKGIWMWCVPHLSKPNHTLVLLDTEGLGDVEKSNPKNDSWIFALAVLL 137
Query: 123 SSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTL 182
SS+FVYNS+ TIN QA++QL+YVTEL IR+KS P +E EDS++F SFFPDF+WT+
Sbjct: 138 SSSFVYNSVSTINHQALEQLHYVTELAELIRAKSCP--RPDEAEDSSEFASFFPDFIWTV 195
Query: 183 RDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPV 242
RDF+L+L+ DG P+T DEYL +LKL G + K + N+PR CIR FF K+KCFVFDRP
Sbjct: 196 RDFTLELKLDGNPITEDEYLENALKLIPGKNPKIQNSNMPRECIRHFFRKRKCFVFDRPT 255
Query: 243 HRRK-LAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTYV 301
+ ++ L ++++ +E L+ F+ Q +FCSYIF+++KTKTL GI V G RL +LV+TYV
Sbjct: 256 NDKQYLNHMDEVPEENLERHFLMQSDNFCSYIFTHAKTKTLREGIIVTGKRLGTLVVTYV 315
Query: 302 NAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSE 361
+AI+SG +PC+ENAV ALAQ+EN AAVQ+A HY QQM Q+++LPT+TLQELLD+H E
Sbjct: 316 DAINSGAVPCLENAVTALAQLENPAAVQRAADHYSQQMAQQLRLPTDTLQELLDVHAACE 375
Query: 362 REAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEE 421
REAI VF+ SFKD +H FQK+L +EKK+ DF QN+EAS+ C A L+ + L E
Sbjct: 376 REAIAVFMEHSFKDENHEFQKKLVDTIEKKKGDFVLQNEEASAKYCQAELKRLSEHLTES 435
Query: 422 VKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQT 481
+ GI+S PGG+ L++++ + ++ Y PRKG++A E+LQ +L+S+ + ++ILQ+D+
Sbjct: 436 ILRGIFSVPGGHNLYLEEKKQVEWDYKLVPRKGVKANEVLQNFLQSQVVVEESILQSDKA 495
Query: 482 LTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQ 541
LT EK I ER E+A+ ++L+E Q++ +QMME +ERS+QE++ Q+ +K+E +R
Sbjct: 496 LTAGEKAIAAERAMKEAAEKEQELLREKQKEQQQMMEAQERSFQEYMAQMEKKLEEEREN 555
Query: 542 LLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRK 587
LL+E ER L KL+ QE++LKE FQK+S + EI L+ K+ K
Sbjct: 556 LLREHERLLKHKLKVQEEMLKEEFQKKSEQLNKEINQLKEKIESTK 601
>gi|157671915 guanylate binding protein family, member 6 [Homo
sapiens]
Length = 633
Score = 627 bits (1618), Expect = e-180
Identities = 311/581 (53%), Positives = 429/581 (73%), Gaps = 3/581 (0%)
Query: 1 MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAG 60
M S M P+CL+EN N +L+ N +A++IL I+QP+VVVAIVGLYRTGKSYLMN LAG
Sbjct: 1 MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAG 60
Query: 61 KKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV 120
+ GF LGSTVQS TKGIWMWCVPHP KP H LVLLDTEGLGDVEKGD +NDSWIFALAV
Sbjct: 61 QNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAV 120
Query: 121 LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVW 180
LL STFVYNS+ TIN QA++QL+YVTELT I++KSSP + VEDS +FVSFFPDF+W
Sbjct: 121 LLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSP--RPDGVEDSTEFVSFFPDFLW 178
Query: 181 TLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR 240
T+RDF+L+L+ +G P+T DEYL +LKL +G + + +T N PR CIR+FFPK+KCFVFDR
Sbjct: 179 TVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDR 238
Query: 241 PVHRRKL-AQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLT 299
P + + L A +EK+ +++LDP+F +Q FCSYIF++++TKTL GI V G RL +L +T
Sbjct: 239 PTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVT 298
Query: 300 YVNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRD 359
YV AI+SG +PC+ENAV+ LAQ ENSAAVQ+A +Y QQM Q+V+LPT+TLQELLD+H
Sbjct: 299 YVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAA 358
Query: 360 SEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLE 419
EREAI +F+ SFKD + FQK+ K+ DF QN+E+S C A L + L
Sbjct: 359 CEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLM 418
Query: 420 EEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTD 479
E + AG +S PGG++L+++ + +++ Y++ PRKG++A+E+ Q +L+S+ + ++ILQ+D
Sbjct: 419 ESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSD 478
Query: 480 QTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDR 539
+ LT++EK + V+R K E+A+ ++L++ ++ +Q ME +++S +E++ QL EK++ +R
Sbjct: 479 KALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMER 538
Query: 540 VQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQ 580
LL+EQ L + Q L EGF+K+ M EI +
Sbjct: 539 EHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFK 579
>gi|45827806 atlastin 3 [Homo sapiens]
Length = 541
Score = 75.5 bits (184), Expect = 1e-13
Identities = 98/394 (24%), Positives = 168/394 (42%), Gaps = 53/394 (13%)
Query: 38 MVVVAIVGLYRTGKSYLMN---------KLAGKKK----------GFSLGSTVQSHTKGI 78
+VVV++ G +R GKS++++ K +G GFS T GI
Sbjct: 60 VVVVSVAGAFRKGKSFILDFMLRYLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGI 119
Query: 79 WMWC-VPHPKKPGH---ILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTI 134
+W V +KPG +VL+DT+G D + ++ + IFAL+ + SS +YN I
Sbjct: 120 QIWSEVFTVEKPGGKKVAVVLMDTQGAFD-SQSTVKDCATIFALSTMTSSVQIYNLSQNI 178
Query: 135 NQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLEADGQ 194
+ + QL TE + + DE F F ++ +RD+S E
Sbjct: 179 QEDDLQQLQLFTEY-----GRLAMDE---------IFQKPFQTLMFLVRDWSFPYEYSYG 224
Query: 195 PLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQ 254
+L L++K+ Q +E N+ R I F CF+ P + + +
Sbjct: 225 LQGGMAFLDKRLQVKE--HQHEEIQNV-RNHIHSCFSDVTCFLLPHPGLQVATSPDFDGK 281
Query: 255 DEELDPEFVQQVADFCSYIFSNSKTKTLS-GGIQVNGPRLESLVLTYVNAISSGDLPCME 313
+++ EF +Q+ Y+ + SK G +V L Y+ DLP +
Sbjct: 282 LKDIAGEFKEQLQALIPYVLNPSKLMEKEINGSKVTCRGLLEYFKAYIKIYQGEDLPHPK 341
Query: 314 NAVLALAQIENSAAVQKAIAHYEQQM-----GQKVQLPTETLQELLDLHRDSEREAIEVF 368
+ + A A+ N AA A Y M G+K L + L+E H + ++ A++ F
Sbjct: 342 SMLQATAEANNLAAAASAKDIYYNNMEEVCGGEKPYLSPDILEE---KHCEFKQLALDHF 398
Query: 369 IRS---SFKDVDHLFQKELAAQLEKKRDDFCKQN 399
++ KD +Q+EL ++++ ++FCK N
Sbjct: 399 KKTKKMGGKDFSFRYQQELEEEIKELYENFCKHN 432
>gi|169160863 PREDICTED: similar to guanylate-binding protein 5
[Homo sapiens]
Length = 112
Score = 69.7 bits (169), Expect = 7e-12
Identities = 37/74 (50%), Positives = 50/74 (67%), Gaps = 1/74 (1%)
Query: 317 LALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDV 376
+ LAQ ENS A+Q+A HY QQM Q+++ PT+ LQELLD+H EREAI VF+ S +
Sbjct: 1 MTLAQRENSVALQRAANHYSQQMAQRMRFPTDMLQELLDMHTACEREAIAVFMEHS-RGE 59
Query: 377 DHLFQKELAAQLEK 390
+ FQK+L + K
Sbjct: 60 NQEFQKKLMSHWGK 73
>gi|189181742 atlastin GTPase 1 isoform b [Homo sapiens]
Length = 553
Score = 65.9 bits (159), Expect = 1e-10
Identities = 88/388 (22%), Positives = 157/388 (40%), Gaps = 58/388 (14%)
Query: 38 MVVVAIVGLYRTGKSYLMNKLAGKK----------------KGFSLGSTVQSHTKGIWMW 81
+V V++ G +R GKS+LM+ + GFS + T GI +W
Sbjct: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
Query: 82 C----VPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQ 137
+ P ++L+DT+G D + ++ + +FAL+ ++SS VYN + +
Sbjct: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
Query: 138 AMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLE----ADG 193
+ L TE ++ F+ F ++ +RD+S E ADG
Sbjct: 186 DLQHLQLFTEYGRLAMEET--------------FLKPFQSLIFLVRDWSFPYEFSYGADG 231
Query: 194 QPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKL 253
++ +LK +Q +E N+ R I F CF+ P +
Sbjct: 232 GAKFLEK------RLKVSGNQHEELQNV-RKHIHSCFTNISCFLLPHPGLKVATNPNFDG 284
Query: 254 QDEELDPEFVQQVADFCSYIFS--NSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPC 311
+ +E+D EF++ + ++ S + K ++G ++ L Y+ +LP
Sbjct: 285 KLKEIDDEFIKNLKILIPWLLSPESLDIKEINGN-KITCRGLVEYFKAYIKIYQGEELPH 343
Query: 312 MENAVLALAQIENSAAVQKAIAHYEQQM-----GQKVQLPTETLQELLDLHRDSEREAIE 366
++ + A A+ N AAV A Y ++M G K L LQ H + E+++
Sbjct: 344 PKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQ---TKHLQLKEESVK 400
Query: 367 VFIRSSFKDVDHLFQKELAAQLEKKRDD 394
+F R K F + QLE + D+
Sbjct: 401 LF-RGVKKMGGEEFSRRYLQQLESEIDE 427
>gi|74024917 atlastin GTPase 1 isoform b [Homo sapiens]
Length = 553
Score = 65.9 bits (159), Expect = 1e-10
Identities = 88/388 (22%), Positives = 157/388 (40%), Gaps = 58/388 (14%)
Query: 38 MVVVAIVGLYRTGKSYLMNKLAGKK----------------KGFSLGSTVQSHTKGIWMW 81
+V V++ G +R GKS+LM+ + GFS + T GI +W
Sbjct: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
Query: 82 C----VPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQ 137
+ P ++L+DT+G D + ++ + +FAL+ ++SS VYN + +
Sbjct: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
Query: 138 AMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLE----ADG 193
+ L TE ++ F+ F ++ +RD+S E ADG
Sbjct: 186 DLQHLQLFTEYGRLAMEET--------------FLKPFQSLIFLVRDWSFPYEFSYGADG 231
Query: 194 QPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKL 253
++ +LK +Q +E N+ R I F CF+ P +
Sbjct: 232 GAKFLEK------RLKVSGNQHEELQNV-RKHIHSCFTNISCFLLPHPGLKVATNPNFDG 284
Query: 254 QDEELDPEFVQQVADFCSYIFS--NSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPC 311
+ +E+D EF++ + ++ S + K ++G ++ L Y+ +LP
Sbjct: 285 KLKEIDDEFIKNLKILIPWLLSPESLDIKEINGN-KITCRGLVEYFKAYIKIYQGEELPH 343
Query: 312 MENAVLALAQIENSAAVQKAIAHYEQQM-----GQKVQLPTETLQELLDLHRDSEREAIE 366
++ + A A+ N AAV A Y ++M G K L LQ H + E+++
Sbjct: 344 PKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQ---TKHLQLKEESVK 400
Query: 367 VFIRSSFKDVDHLFQKELAAQLEKKRDD 394
+F R K F + QLE + D+
Sbjct: 401 LF-RGVKKMGGEEFSRRYLQQLESEIDE 427
>gi|19923445 atlastin GTPase 1 isoform a [Homo sapiens]
Length = 558
Score = 65.9 bits (159), Expect = 1e-10
Identities = 88/388 (22%), Positives = 157/388 (40%), Gaps = 58/388 (14%)
Query: 38 MVVVAIVGLYRTGKSYLMNKLAGKK----------------KGFSLGSTVQSHTKGIWMW 81
+V V++ G +R GKS+LM+ + GFS + T GI +W
Sbjct: 67 VVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIW 126
Query: 82 C----VPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQ 137
+ P ++L+DT+G D + ++ + +FAL+ ++SS VYN + +
Sbjct: 127 SEIFLINKPDGKKVAVLLMDTQGTFD-SQSTLRDSATVFALSTMISSIQVYNLSQNVQED 185
Query: 138 AMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLE----ADG 193
+ L TE ++ F+ F ++ +RD+S E ADG
Sbjct: 186 DLQHLQLFTEYGRLAMEET--------------FLKPFQSLIFLVRDWSFPYEFSYGADG 231
Query: 194 QPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKL 253
++ +LK +Q +E N+ R I F CF+ P +
Sbjct: 232 GAKFLEK------RLKVSGNQHEELQNV-RKHIHSCFTNISCFLLPHPGLKVATNPNFDG 284
Query: 254 QDEELDPEFVQQVADFCSYIFS--NSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPC 311
+ +E+D EF++ + ++ S + K ++G ++ L Y+ +LP
Sbjct: 285 KLKEIDDEFIKNLKILIPWLLSPESLDIKEINGN-KITCRGLVEYFKAYIKIYQGEELPH 343
Query: 312 MENAVLALAQIENSAAVQKAIAHYEQQM-----GQKVQLPTETLQELLDLHRDSEREAIE 366
++ + A A+ N AAV A Y ++M G K L LQ H + E+++
Sbjct: 344 PKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQ---TKHLQLKEESVK 400
Query: 367 VFIRSSFKDVDHLFQKELAAQLEKKRDD 394
+F R K F + QLE + D+
Sbjct: 401 LF-RGVKKMGGEEFSRRYLQQLESEIDE 427
>gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens]
Length = 583
Score = 62.8 bits (151), Expect = 9e-10
Identities = 91/390 (23%), Positives = 162/390 (41%), Gaps = 48/390 (12%)
Query: 38 MVVVAIVGLYRTGKSYLM--------NK-----LAGKKK---GFSLGSTVQSHTKGIWMW 81
+VVV++ G +R GKS+L+ NK + G + GF+ + T GI +W
Sbjct: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153
Query: 82 ----CVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQ 137
+ P ++L+DT+G D + ++ + +FAL+ + SS VYN I +
Sbjct: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212
Query: 138 AMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLEADGQPLT 197
+ L TE + + F ++ +RD+S E
Sbjct: 213 DLQHLQLFTEY--------------GRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEG 258
Query: 198 PDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQDEE 257
++L L++K+ +Q +E N+ R I F CF+ P + + ++
Sbjct: 259 GKQFLEKRLQVKQ--NQHEELQNV-RKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKD 315
Query: 258 LDPEFVQQVADFCSYIFS--NSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENA 315
+D +F +++ + + + N K +SG +V L Y+ +LP ++
Sbjct: 316 IDEDFKRELRNLVPLLLAPENLVEKEISGS-KVTCRDLVEYFKAYIKIYQGEELPHPKSM 374
Query: 316 VLALAQIENSAAVQKAIAHYEQQMGQKV--QLPTETLQELLDLHRDSEREAIEVFIRSSF 373
+ A A+ N AAV A Y + M Q P +L H D + AI+ F RS
Sbjct: 375 LQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQF-RSVK 433
Query: 374 K----DVDHLFQKELAAQLEKKRDDFCKQN 399
K + +Q +L A++E+ +F K N
Sbjct: 434 KMGGDEFCRRYQDQLEAEIEETYANFIKHN 463
>gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens]
Length = 579
Score = 62.8 bits (151), Expect = 9e-10
Identities = 91/390 (23%), Positives = 162/390 (41%), Gaps = 48/390 (12%)
Query: 38 MVVVAIVGLYRTGKSYLM--------NK-----LAGKKK---GFSLGSTVQSHTKGIWMW 81
+VVV++ G +R GKS+L+ NK + G + GF+ + T GI +W
Sbjct: 94 IVVVSVAGAFRKGKSFLLDFMLRYMYNKDSQSWIGGNNEPLTGFTWRGGCERETTGIQVW 153
Query: 82 ----CVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQ 137
+ P ++L+DT+G D + ++ + +FAL+ + SS VYN I +
Sbjct: 154 NEVFVIDRPNGTKVAVLLMDTQGAFD-SQSTIKDCATVFALSTMTSSVQVYNLSQNIQED 212
Query: 138 AMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLEADGQPLT 197
+ L TE + + F ++ +RD+S E
Sbjct: 213 DLQHLQLFTEY--------------GRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEG 258
Query: 198 PDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQDEE 257
++L L++K+ +Q +E N+ R I F CF+ P + + ++
Sbjct: 259 GKQFLEKRLQVKQ--NQHEELQNV-RKHIHNCFSNLGCFLLPHPGLKVATNPSFDGRLKD 315
Query: 258 LDPEFVQQVADFCSYIFS--NSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENA 315
+D +F +++ + + + N K +SG +V L Y+ +LP ++
Sbjct: 316 IDEDFKRELRNLVPLLLAPENLVEKEISGS-KVTCRDLVEYFKAYIKIYQGEELPHPKSM 374
Query: 316 VLALAQIENSAAVQKAIAHYEQQMGQKV--QLPTETLQELLDLHRDSEREAIEVFIRSSF 373
+ A A+ N AAV A Y + M Q P +L H D + AI+ F RS
Sbjct: 375 LQATAEANNLAAVAGARDTYCKSMEQVCGGDKPYIAPSDLERKHLDLKEVAIKQF-RSVK 433
Query: 374 K----DVDHLFQKELAAQLEKKRDDFCKQN 399
K + +Q +L A++E+ +F K N
Sbjct: 434 KMGGDEFCRRYQDQLEAEIEETYANFIKHN 463
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 60.8 bits (146), Expect = 3e-09
Identities = 55/246 (22%), Positives = 119/246 (48%), Gaps = 29/246 (11%)
Query: 350 LQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSA 409
LQE L L +SE+ I++ + KEL +LE+ + +Q +A +D
Sbjct: 214 LQEKLQLV-ESEKSEIQLNV------------KELKRKLERAKLLLPQQQLQAEADHLGK 260
Query: 410 LLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKE 469
LQ + + L+ +V+ L+ + Q ++K + + K + EE +Q +
Sbjct: 261 ELQSVSAKLQAQVEEN--------ELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIR 312
Query: 470 SMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLK 529
+ + + ++ + EKE+++ + + + L+E + E++ EQ+E+ +E
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 372
Query: 530 QLTEKMENDRVQLLKEQE--RTLALKLQEQEQLLKE-----GFQKESR-IMKNEIQDLQT 581
+ EK + ++ +++E R K++EQE++++E G Q+E + E+Q+ +
Sbjct: 373 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 582 KMRRRK 587
KMRR++
Sbjct: 433 KMRRQE 438
Score = 48.5 bits (114), Expect = 2e-05
Identities = 28/130 (21%), Positives = 69/130 (53%), Gaps = 2/130 (1%)
Query: 438 QKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAE 497
+K+++ +KK E+ K + EE++Q + + + + + E+E+++ + K
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Query: 498 SAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQ 557
+ + +E R+ E+MM+++E E +++ E + +++Q +E+ R K++EQ
Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE--QEEKMQEQEEKMRRQEEKMREQ 556
Query: 558 EQLLKEGFQK 567
E L++ +K
Sbjct: 557 EVRLRQQEEK 566
Score = 48.1 bits (113), Expect = 2e-05
Identities = 42/212 (19%), Positives = 105/212 (49%), Gaps = 14/212 (6%)
Query: 381 QKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPL--EEEVKAGIYSKPGGYRLFVQ 438
Q+E + EK R+ +Q QEA R ++ + +EE+ K G +
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQE---E 418
Query: 439 KLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAES 498
K+ + +++ E+ K + EE ++ K + I + ++ + E+E+++ + K
Sbjct: 419 KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478
Query: 499 AQASAKMLQEMQRKNEQMMEQKE---RSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQ 555
+A + +E R+ E+ + ++E R +E +++ E M+ ++ +++E K+
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE-----KMC 533
Query: 556 EQEQLLKEGFQKESRIMKNEIQDLQTKMRRRK 587
EQE+ ++E +K R + ++++ + ++R+++
Sbjct: 534 EQEEKMQEQEEKMRR-QEEKMREQEVRLRQQE 564
Score = 37.7 bits (86), Expect = 0.030
Identities = 40/209 (19%), Positives = 90/209 (43%), Gaps = 35/209 (16%)
Query: 321 QIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLF 380
Q E ++ + E++MG++ + E +E+ + R+ E IR
Sbjct: 395 QEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ--EEKIREQ-------- 444
Query: 381 QKELAAQLEKKRD--DFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQ 438
+K++ Q EK R+ + ++ +E ++ + + E+E K R +
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKM---------RRQEE 495
Query: 439 KLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAES 498
K+++ +KK E+ K + EE++Q + ++ + E+E+++ + K +
Sbjct: 496 KIREQEKKIREQEEKIREQEEMMQ--------------EQEEKMWEQEEKMCEQEEKMQE 541
Query: 499 AQASAKMLQEMQRKNEQMMEQKERSYQEH 527
+ + +E R+ E + Q+E QEH
Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 33.9 bits (76), Expect = 0.43
Identities = 35/192 (18%), Positives = 84/192 (43%), Gaps = 8/192 (4%)
Query: 398 QNQEASSDRCSALLQVI--FSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGI 455
Q+QEA A +Q I + + E++ +Y + + +DL + ++ +
Sbjct: 104 QHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 163
Query: 456 QAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQ 515
+ E+ L K+ I + LT++ + +E + K ++ Q
Sbjct: 164 ELEQALSAVATQKKKADRYI----EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 219
Query: 516 MMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNE 575
++E ++ Q ++K+L K+E ++ L ++Q + A L ++ Q + Q +++ +NE
Sbjct: 220 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ--AQVEENE 277
Query: 576 IQDLQTKMRRRK 587
+ + + + K
Sbjct: 278 LWNRLNQQQEEK 289
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 54.7 bits (130), Expect = 2e-07
Identities = 64/272 (23%), Positives = 119/272 (43%), Gaps = 36/272 (13%)
Query: 323 ENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLH-RDSEREAIEVFIRSSFKDVDHLFQ 381
E + +A +++ M + P T E H +DS +AIE KD + LF
Sbjct: 699 EKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIE-----KMKDREALFN 753
Query: 382 KELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEE--EVKAGIYSKPGGYRLFVQK 439
+ +AA +K+++D + ++ SD L +VK + S P +
Sbjct: 754 EFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSS 813
Query: 440 L-QDLKKKYYEEPRKGIQAEEI--LQTYLKSKESMTDAILQTDQTLTEKEKEIEVERV-- 494
+ +DL K+Y E+ K + +E+ L+ + + S+ + + + +E+ KEI+ ER
Sbjct: 814 MREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQH 873
Query: 495 -KAESAQASAKMLQEMQRKNEQMM---------------------EQKERSYQEHLKQLT 532
+ E+ Q +L +M R ++ E+KE+ + EH++ LT
Sbjct: 874 KREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALT 933
Query: 533 EKMENDRVQLLKEQER-TLALKLQEQEQLLKE 563
+K QLL E TL +E ++++KE
Sbjct: 934 KKKREHFRQLLDETSAITLTSTWKEVKKIIKE 965
Score = 32.7 bits (73), Expect = 0.96
Identities = 32/161 (19%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 440 LQDLKKKYYEEPRK-GIQAEEILQTYLKSKESMTDAILQTDQTLTEK-----------EK 487
+++LKK + P IQ + + +K ++ + + I + + +K EK
Sbjct: 560 MEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEK 619
Query: 488 EIEVE-RVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQ 546
E +E +KA +A + M++ + ++E+ ++ K+L + + + R LL +
Sbjct: 620 EAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPK 679
Query: 547 ERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRK 587
ER + + +E +K+++IM+ + +D + M K
Sbjct: 680 ERKQVFDQYVKTRAEEERREKKNKIMQAK-EDFKKMMEEAK 719
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 54.7 bits (130), Expect = 2e-07
Identities = 64/272 (23%), Positives = 119/272 (43%), Gaps = 36/272 (13%)
Query: 323 ENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLH-RDSEREAIEVFIRSSFKDVDHLFQ 381
E + +A +++ M + P T E H +DS +AIE KD + LF
Sbjct: 720 EKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIE-----KMKDREALFN 774
Query: 382 KELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEE--EVKAGIYSKPGGYRLFVQK 439
+ +AA +K+++D + ++ SD L +VK + S P +
Sbjct: 775 EFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSS 834
Query: 440 L-QDLKKKYYEEPRKGIQAEEI--LQTYLKSKESMTDAILQTDQTLTEKEKEIEVERV-- 494
+ +DL K+Y E+ K + +E+ L+ + + S+ + + + +E+ KEI+ ER
Sbjct: 835 MREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQH 894
Query: 495 -KAESAQASAKMLQEMQRKNEQMM---------------------EQKERSYQEHLKQLT 532
+ E+ Q +L +M R ++ E+KE+ + EH++ LT
Sbjct: 895 KREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALT 954
Query: 533 EKMENDRVQLLKEQER-TLALKLQEQEQLLKE 563
+K QLL E TL +E ++++KE
Sbjct: 955 KKKREHFRQLLDETSAITLTSTWKEVKKIIKE 986
Score = 32.7 bits (73), Expect = 0.96
Identities = 32/161 (19%), Positives = 74/161 (45%), Gaps = 14/161 (8%)
Query: 440 LQDLKKKYYEEPRK-GIQAEEILQTYLKSKESMTDAILQTDQTLTEK-----------EK 487
+++LKK + P IQ + + +K ++ + + I + + +K EK
Sbjct: 581 MEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEK 640
Query: 488 EIEVE-RVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQ 546
E +E +KA +A + M++ + ++E+ ++ K+L + + + R LL +
Sbjct: 641 EAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPK 700
Query: 547 ERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRK 587
ER + + +E +K+++IM+ + +D + M K
Sbjct: 701 ERKQVFDQYVKTRAEEERREKKNKIMQAK-EDFKKMMEEAK 740
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 54.3 bits (129), Expect = 3e-07
Identities = 57/252 (22%), Positives = 128/252 (50%), Gaps = 19/252 (7%)
Query: 336 EQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKE--LAAQLEKKRD 393
++Q+ +++Q L+++ DLH +E+ + +R + ++ L Q + + A+ +++
Sbjct: 320 QEQLDERLQ----ELEKIKDLHM-AEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMH 374
Query: 394 DFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRK 453
+ + +E + S + Q+ EE + S+ + + L +K EE R+
Sbjct: 375 ETLEMKEEEIAQLRSRIKQMTTQG-EELREQKEKSERAAFEELEKALSTAQKT--EEARR 431
Query: 454 GIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKML--QEMQR 511
++AE Q K S + I + K++ ++V + +E A + L +E+ R
Sbjct: 432 KLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR 491
Query: 512 KNEQM---MEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKE 568
K +++ ++ +ER +QE +K EK +++ +++ +E+E+ +L L+E E L K+ E
Sbjct: 492 KEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELE-LQKKAILTE 550
Query: 569 SRIMKNEIQDLQ 580
S +N+++DLQ
Sbjct: 551 S---ENKLRDLQ 559
Score = 52.0 bits (123), Expect = 2e-06
Identities = 51/268 (19%), Positives = 120/268 (44%), Gaps = 31/268 (11%)
Query: 323 ENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQK 382
E ++Q+ ++ +Q++ ++ +E L + E E + + + FQ+
Sbjct: 450 EERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQE 509
Query: 383 ELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQD 442
++ LEK + ++ K +QE AL + LE + KA + KL+D
Sbjct: 510 QMKVALEKSQSEYLKISQEKEQQESLALEE-----LELQKKAILTESEN-------KLRD 557
Query: 443 LKKKYYEEPRKGIQAEEILQTYLKSKESMTDAI---LQTDQTLTEKEKEIEVERVKAESA 499
L+++ + ++ E L+ L+ ++ + + L+ ++ KE + VE+ K E
Sbjct: 558 LQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTE-- 615
Query: 500 QASAKMLQEMQRKNEQMMEQK----ERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQ 555
L+ ++ + + + +K ++ YQ +++L EK E ++ LLK++E ++
Sbjct: 616 ------LESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIE 669
Query: 556 EQEQLLKEGFQKESRIMKNEIQDLQTKM 583
E + E + + E++ L +++
Sbjct: 670 EMNEKTLEKLD----VKQTELESLSSEL 693
Score = 49.3 bits (116), Expect = 1e-05
Identities = 64/303 (21%), Positives = 138/303 (45%), Gaps = 48/303 (15%)
Query: 312 MENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRS 371
+E + +I Q+++A E ++ QK + TE+ +L DL +++E R+
Sbjct: 515 LEKSQSEYLKISQEKEQQESLALEELEL-QKKAILTESENKLRDLQQEAET------YRT 567
Query: 372 SFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPG 431
+++ +K L + +D + EA ++ + + V+ + E+++ + +
Sbjct: 568 RILELESSLEKSLQENKNQSKD--LAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 625
Query: 432 GYRLFVQKLQDLKKKYYEEPRK-GIQAEEILQTYLKSKESMTDAILQ--TDQTLTEKE-K 487
L+ +KLQ LK++Y E K + E+ +T LK KE + A ++ ++TL + + K
Sbjct: 626 ---LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVK 682
Query: 488 EIEVERVKAESAQA-----------------SAKMLQEMQRKNEQMMEQKERSYQEHLK- 529
+ E+E + +E ++ + KM QE++ K ++ ++ +K
Sbjct: 683 QTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKE 742
Query: 530 -----QLTEKMENDRVQ----LLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQ 580
Q TEK D++ LLKE+++ L ++ Q E + + + + E+Q
Sbjct: 743 HEVSIQRTEKALKDQINQLELLLKERDKHL-----KEHQAHVENLEADIKRSEGELQQAS 797
Query: 581 TKM 583
K+
Sbjct: 798 AKL 800
Score = 46.6 bits (109), Expect = 6e-05
Identities = 69/294 (23%), Positives = 120/294 (40%), Gaps = 37/294 (12%)
Query: 323 ENSAAVQKAIAHYEQQMGQKVQLPTETLQELLD-------LHRDSEREAIEVFIRSSFKD 375
E+ ++Q+ + Q+ Q L E + L + L D +R E+ S+ D
Sbjct: 742 EHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 801
Query: 376 VDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRL 435
V +Q Q + + + Q+ +L E K + ++ +++
Sbjct: 802 VFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKI 861
Query: 436 FVQKL-QDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKE-------- 486
VQ L Q L+K+ E +K + + Q Y E QT Q L EKE
Sbjct: 862 QVQDLMQQLEKQNSEMEQK---VKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMRE 918
Query: 487 ---KEIEVERVKAESAQASAKMLQE-------MQRKNEQMMEQKERSYQEHLKQLTEKME 536
KEIE+ K + + S +L E Q K + ++QK + QE LK +K+
Sbjct: 919 GQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLK---KKLL 975
Query: 537 NDRVQLLKEQERTLALKLQEQEQ----LLKEGFQKESRIMKNEIQDLQTKMRRR 586
+ +L KE E T AL+L ++E+ + E Q S + + + L+T + +
Sbjct: 976 DQEAKLKKELENT-ALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQ 1028
Score = 42.0 bits (97), Expect = 0.002
Identities = 60/255 (23%), Positives = 110/255 (43%), Gaps = 44/255 (17%)
Query: 350 LQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQ------NQEAS 403
L E+L E E S KD ++EL A+++++++ +Q E S
Sbjct: 693 LSEVLKARHKLEEEL------SVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 746
Query: 404 SDRCSALLQVIFSPLE-----------------EEVKAGIYSKPGGYRLFVQKLQDLKKK 446
R L+ + LE E ++A I G + KL D+ +
Sbjct: 747 IQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKL-DVFQS 805
Query: 447 YYEEPRKGIQA--EEILQTYLKSKESMTDAILQTDQTL-TEKEKEIEVERVKAESAQASA 503
Y + +A E++ Q K + T+ IL T Q E +K+ + A Q
Sbjct: 806 YQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQ- 864
Query: 504 KMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLL-- 561
++Q+++++N +M EQK +K LT+ E+ KEQE+T + ++++ +L
Sbjct: 865 DLMQQLEKQNSEM-EQK-------VKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQM 916
Query: 562 KEGFQKESRIMKNEI 576
+EG +KE I+ ++
Sbjct: 917 REGQKKEIEILTQKL 931
Score = 41.2 bits (95), Expect = 0.003
Identities = 46/151 (30%), Positives = 70/151 (46%), Gaps = 17/151 (11%)
Query: 418 LEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQ 477
L E +K K ++ VQKLQ ++ E+ + +AEE + T SM A L+
Sbjct: 1544 LNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMK-AELE 1602
Query: 478 TDQ------TLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQL 531
T + L+ K KE E++ ++ SA L E++RK EQ + + KQL
Sbjct: 1603 TKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIK-------KQL 1655
Query: 532 TEKMENDRVQLLKEQERTLA---LKLQEQEQ 559
+ME Q K E L+ KLQE+E+
Sbjct: 1656 LSQMEEKEEQYKKGTESHLSELNTKLQERER 1686
Score = 39.7 bits (91), Expect = 0.008
Identities = 42/177 (23%), Positives = 77/177 (43%), Gaps = 28/177 (15%)
Query: 384 LAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDL 443
L + +++R++ KQ QE + ++ L+ + ++ QK Q+L
Sbjct: 1967 LKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQL--------------AQKEQEL 2012
Query: 444 KKKYYEEPRKGIQAE-EILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQAS 502
+ E K + E E+L+++ + + I + D L K E E + A + +
Sbjct: 2013 EMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYE-EILDAREEEMT 2071
Query: 503 AKM------LQEMQRKNEQMMEQKER------SYQEHLKQLTEKMENDRVQLLKEQE 547
AK+ L+E+Q+K +Q +EQ+E + E QL +K LKEQE
Sbjct: 2072 AKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQE 2128
Score = 38.9 bits (89), Expect = 0.013
Identities = 50/211 (23%), Positives = 97/211 (45%), Gaps = 29/211 (13%)
Query: 398 QNQEASSDRCSALLQVIFSPLEEEVK------AGIYSKPGGYRLFVQKLQDLKKKYYEEP 451
++ EA +++ + LEE+ K A K GG + +Q Q+L+ +++
Sbjct: 1781 EHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGG-KNNIQAKQNLEN-VFDDV 1838
Query: 452 RKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQR 511
+K +Q +E+ L+ K I + D L +++ VE + S + LQ+M
Sbjct: 1839 QKTLQEKELTCQILEQK------IKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDG 1892
Query: 512 KN------EQMMEQKERSYQEHLKQLT--EKMENDRVQLLKEQERTLA------LKLQEQ 557
+N E+ E+K +S+ K L+ E ND L ER ++LQ+
Sbjct: 1893 RNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKD 1952
Query: 558 EQLLKEGFQKESRIMKNEI-QDLQTKMRRRK 587
++L++ Q+E I+K E Q+ + K+++ +
Sbjct: 1953 LRMLRKEHQQELEILKKEYDQEREEKIKQEQ 1983
Score = 38.5 bits (88), Expect = 0.018
Identities = 54/252 (21%), Positives = 103/252 (40%), Gaps = 17/252 (6%)
Query: 348 ETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQ------LEKKRDDFCKQNQE 401
E L EL L + +R+ E + S K D FQ ++ LE K +F K ++E
Sbjct: 1155 EQLVELKMLAEEDKRKVSE--LTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1212
Query: 402 ASS--DRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYE----EPRKGI 455
+ D C + + E+ SK + Q K E +
Sbjct: 1213 LAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVS 1272
Query: 456 QAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQ 515
+ E L+ + + ++ + Q L EKE +I+ + ES + LQ+ +Q
Sbjct: 1273 ELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQ 1332
Query: 516 MMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQE-QEQLLKEGFQKESRIMKN 574
+KE + K+L+E + + V L+KE+ + +++ +QL Q ++ I +
Sbjct: 1333 AASEKESCITQLKKELSENI--NAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLS 1390
Query: 575 EIQDLQTKMRRR 586
E + + +R++
Sbjct: 1391 EKEAAISSLRKQ 1402
Score = 38.5 bits (88), Expect = 0.018
Identities = 38/166 (22%), Positives = 78/166 (46%), Gaps = 36/166 (21%)
Query: 437 VQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKE----KEIEVE 492
++ L ++ K Y ++ K I+ +E++Q LQ Q L E++ KE E +
Sbjct: 1541 IESLNEVLKNYNQQ--KDIEHKELVQK------------LQHFQELGEEKDNRVKEAEEK 1586
Query: 493 RVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERT--- 549
+ E+ S K E ++K + + +S +E LK L +++E++ L E +R
Sbjct: 1587 ILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQ 1646
Query: 550 --------LALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRK 587
L +++E+E+ K+G ++ + +L TK++ R+
Sbjct: 1647 KIAAIKKQLLSQMEEKEEQYKKG-------TESHLSELNTKLQERE 1685
Score = 37.7 bits (86), Expect = 0.030
Identities = 49/199 (24%), Positives = 90/199 (45%), Gaps = 21/199 (10%)
Query: 384 LAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDL 443
+ A+LE K+ + N S L+ + LE E A + R QK+ +
Sbjct: 1597 MKAELETKKKELEHVNLSVKSKEEE--LKALEDRLESESAAKLAELK---RKAEQKIAAI 1651
Query: 444 KKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEV--ERVKA-ESAQ 500
KK+ Q EE + Y K ES + + + L E+E+E+ + E++K+ ES+Q
Sbjct: 1652 KKQLLS------QMEEKEEQYKKGTESH---LSELNTKLQEREREVHILEEKLKSVESSQ 1702
Query: 501 ASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQL 560
+ ++ + EQ+E Q +++ E+ + + L E+E+ L QE+E+
Sbjct: 1703 SETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEET 1762
Query: 561 LKEGF----QKESRIMKNE 575
+ F Q + R++K E
Sbjct: 1763 VSSHFEMRCQYQERLIKLE 1781
Score = 37.4 bits (85), Expect = 0.039
Identities = 75/312 (24%), Positives = 139/312 (44%), Gaps = 53/312 (16%)
Query: 305 SSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQ--LPTETLQELLDLHRDSER 362
S G+L +A L + Q SA ++ A YE+Q+ Q Q L ET + +L + +E
Sbjct: 789 SEGELQ-QASAKLDVFQSYQSATHEQTKA-YEEQLAQLQQKLLDLET-ERILLTKQVAEV 845
Query: 363 EAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEV 422
EA + + + D + ++L QLEK QN E + +L QV S LE+
Sbjct: 846 EAQKKDVCTEL-DAHKIQVQDLMQQLEK-------QNSEMEQ-KVKSLTQVYESKLEDGN 896
Query: 423 KAGIYSKPGGYRLFVQK------LQDLKKKYYEEPRKGIQAEE----IL----QTYLKSK 468
K +K ++ V+K +++ +KK E + + A+E IL +T K++
Sbjct: 897 KEQEQTK----QILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQ 952
Query: 469 ESMTDAILQTDQTLTE--------------KEKEIEVERVKAESAQASAKMLQEMQRKN- 513
E + + Q + + E KE E + + Q +AKML+ Q +
Sbjct: 953 EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSA 1012
Query: 514 --EQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRI 571
+ + E + +E ++ LTE + ++ E+ KL +Q + L+E + + +
Sbjct: 1013 GISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEK----KLNQQAEELQEIHEIQLQE 1068
Query: 572 MKNEIQDLQTKM 583
+ E+ +L+ K+
Sbjct: 1069 KEQEVAELKQKI 1080
Score = 35.4 bits (80), Expect = 0.15
Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 12/110 (10%)
Query: 484 EKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLL 543
E+E++I+ E+ E S L+++ R+ + QKE+ + +K+ K + +LL
Sbjct: 1974 EREEKIKQEQEDLELKHNST--LKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELL 2031
Query: 544 ---KEQERTLALKLQEQEQLLKEGFQKESRI-------MKNEIQDLQTKM 583
+E+ L K+ E++ LK ++ I M +++DLQT++
Sbjct: 2032 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQL 2081
Score = 35.0 bits (79), Expect = 0.19
Identities = 62/320 (19%), Positives = 129/320 (40%), Gaps = 41/320 (12%)
Query: 291 PRLESLVLTYVNAISSGDLPCMEN------AVLALAQIENSAAVQKAIAHYEQQMGQKVQ 344
PR V Y + C++ +VL E +Q+ E+ + +
Sbjct: 1709 PRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFE 1768
Query: 345 LPTETLQELLDLH----RDSEREAIEVFIRSSFKDVDHLFQKELAAQLEK---KRDDFCK 397
+ + + L+ L + E +++ ++ ++ + + +A +EK K + K
Sbjct: 1769 MRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAK 1828
Query: 398 QNQEASSDRCSALLQ---VIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKG 454
QN E D LQ + LE+++K + ++++L KY E +
Sbjct: 1829 QNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKY--EKLQA 1886
Query: 455 IQA-------EEILQ--TYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKM 505
+Q E+L+ T KSK + L ++ + E ++ + E + ++
Sbjct: 1887 LQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEI 1946
Query: 506 ------LQEMQRKNEQMMEQKERSY----QEHLKQLTEKME----NDRVQLLKEQERTLA 551
L+ ++++++Q +E ++ Y +E +KQ E +E + QL++E LA
Sbjct: 1947 VRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLA 2006
Query: 552 LKLQEQEQLLKEGFQKESRI 571
K QE E +KE K +
Sbjct: 2007 QKEQELEMTIKETINKAQEV 2026
Score = 33.1 bits (74), Expect = 0.74
Identities = 57/275 (20%), Positives = 110/275 (40%), Gaps = 40/275 (14%)
Query: 322 IENSAAVQKAIAHYEQQMGQKVQLPTETLQELLD------LHRDSEREAIEVFIRSSFKD 375
+ A+QK + +Q +K T+ +EL + L ++ +E +V I S K
Sbjct: 1317 VTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEK-KVEISSLSKQ 1375
Query: 376 VDHL-FQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYR 434
+ L Q + + L +K ++ ++C L QV + K SK
Sbjct: 1376 LTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQV----QDLSFKVDTLSKEKISA 1431
Query: 435 LFVQKLQDLKKKYYEEPRKGIQA---------EEILQTYLKSKESMTDAILQTDQTLTEK 485
L +++ D K+ E +K E +Q LKSKE+ EK
Sbjct: 1432 L--EQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAY------------EK 1477
Query: 486 EKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKE 545
+++I + + + + L+ ++ ME+KE + + LK T R+ L++
Sbjct: 1478 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTA-----RIMELED 1532
Query: 546 QERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQ 580
++++ ++LK Q++ K +Q LQ
Sbjct: 1533 HITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQ 1567
Score = 30.8 bits (68), Expect = 3.7
Identities = 47/206 (22%), Positives = 82/206 (39%), Gaps = 17/206 (8%)
Query: 369 IRSSFKDVDHLFQKEL---AAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAG 425
++ D + +KEL A +L +K F + E + + + + S LE K
Sbjct: 970 LKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAV-SRLETNQKEQ 1028
Query: 426 IYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKE--SMTDAILQTDQTLT 483
I S +R + + + +K + + +Q +Q K +E + IL
Sbjct: 1029 IESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKE 1088
Query: 484 EKEKEIEVERVKAESAQASAKMLQEMQRKNE---QMMEQKERSYQEHLKQLTEKMENDRV 540
E KEI + + + LQE ++ + Q E + HL EK+E D
Sbjct: 1089 EMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHL----EKLEVDLN 1144
Query: 541 QLLKE----QERTLALKLQEQEQLLK 562
+ LKE QE+ + LK+ +E K
Sbjct: 1145 KSLKENTFLQEQLVELKMLAEEDKRK 1170
Score = 29.6 bits (65), Expect = 8.2
Identities = 40/204 (19%), Positives = 88/204 (43%), Gaps = 27/204 (13%)
Query: 389 EKKRDDFCKQNQEASSDRCSALLQVIFSP------LEEEVKAGIYSKPGGYRLFVQKLQD 442
+KK Q+Q+ S R + L + + L+EE A + K + ++
Sbjct: 171 KKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSL 230
Query: 443 LKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQAS 502
LK++ R G ++L+ L E + + + ++ E +E ++ +
Sbjct: 231 LKQRL----RNGPMNVDVLKP-LPQLEPQAEVFTKEENPESDGEPVVE-----DGTSVKT 280
Query: 503 AKMLQEMQRKNEQMMEQKERSYQEHLKQLT------EKMENDRVQLLKEQERTLALKLQE 556
+ LQ+ ++ E ++++ + + Q H +Q T E ++ + L+E E+ L + E
Sbjct: 281 LETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAE 340
Query: 557 QEQLLKEGFQKESRIMKNEIQDLQ 580
+ +L+ + R KN I+ L+
Sbjct: 341 KTKLI-----TQLRDAKNLIEQLE 359
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 54.3 bits (129), Expect = 3e-07
Identities = 40/155 (25%), Positives = 79/155 (50%), Gaps = 8/155 (5%)
Query: 438 QKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAE 497
++L+++K K E RK +QA E ++ + K+ + TEK KE + KA+
Sbjct: 565 RRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 624
Query: 498 SAQASAKMLQEMQRKNEQMME-------QKERSYQEHLKQLTEKMENDRVQLLKEQERTL 550
+A+AK ++E++ + +Q E Q+E + H + L +K E ++ +L K E
Sbjct: 625 K-KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR 683
Query: 551 ALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRR 585
+ +EQE+ +E ++E R + Q+ + + R+
Sbjct: 684 LAEQREQERREQERREQERREQERREQERREQERQ 718
Score = 44.7 bits (104), Expect = 2e-04
Identities = 62/263 (23%), Positives = 119/263 (45%), Gaps = 54/263 (20%)
Query: 368 FIRSSFKDVDHLFQKELAAQLEKKR--DDFCKQNQEASSDRCSALLQVI-----FSPLEE 420
F+ + +++L +KE A QL +++ +D ++ +E R L +V+ ++E
Sbjct: 534 FVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKE 593
Query: 421 EVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQA-----EEILQTYLKSKESMTDAI 475
E K I K + +K + K++ E + +A EE+ + +E+
Sbjct: 594 EKKKQIEQK---FAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRW 650
Query: 476 LQTD------QTLTEKEKEIEVERV-KAESAQASAKMLQEMQRKNE-------------- 514
LQ + Q L +K+KE E ER+ KA A+ A+ ++ +R+ E
Sbjct: 651 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 710
Query: 515 -------QMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQK 567
Q+ EQ+ R QE L+ E L+E+E+ L L+ ++ ++ L+E +K
Sbjct: 711 ERREQERQLAEQERRREQERLQAERE---------LQEREKALRLQKEQLQRELEEKKKK 761
Query: 568 E--SRIMKNEIQDLQTKMRRRKA 588
E R+ + ++Q+ Q K + A
Sbjct: 762 EEQQRLAERQLQEEQEKKAKEAA 784
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 54.3 bits (129), Expect = 3e-07
Identities = 40/155 (25%), Positives = 79/155 (50%), Gaps = 8/155 (5%)
Query: 438 QKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAE 497
++L+++K K E RK +QA E ++ + K+ + TEK KE + KA+
Sbjct: 561 RRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 620
Query: 498 SAQASAKMLQEMQRKNEQMME-------QKERSYQEHLKQLTEKMENDRVQLLKEQERTL 550
+A+AK ++E++ + +Q E Q+E + H + L +K E ++ +L K E
Sbjct: 621 K-KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR 679
Query: 551 ALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRR 585
+ +EQE+ +E ++E R + Q+ + + R+
Sbjct: 680 LAEQREQERREQERREQERREQERREQERREQERQ 714
Score = 44.3 bits (103), Expect = 3e-04
Identities = 52/262 (19%), Positives = 111/262 (42%), Gaps = 38/262 (14%)
Query: 336 EQQMGQKVQLPTETLQELLDLHRDSE-------REAIEVFIRSSFKDVDHLFQKELAAQL 388
EQ QKV+ E + L R+ RE +E K ++ F AQ+
Sbjct: 548 EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF-----AQI 602
Query: 389 EKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYY 448
++K + ++ + A + + EEV+A + RL ++
Sbjct: 603 DEKTEKAKEERLAEEKAKKKAAAKKM-----EEVEARRKQEEEARRL----------RWL 647
Query: 449 EEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQE 508
++ + + +E+LQ + ++ + + ++E+E + + + + + QE
Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707
Query: 509 MQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKE 568
+ + Q+ EQ+ R QE L+ E L+E+E+ L L+ ++ ++ L+E +KE
Sbjct: 708 RREQERQLAEQERRREQERLQAERE---------LQEREKALRLQKEQLQRELEEKKKKE 758
Query: 569 --SRIMKNEIQDLQTKMRRRKA 588
R+ + ++Q+ Q K + A
Sbjct: 759 EQQRLAERQLQEEQEKKAKEAA 780
Score = 33.1 bits (74), Expect = 0.74
Identities = 29/140 (20%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
Query: 455 IQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKML--QEMQRK 512
+Q ++L T + S+ + ++ + L KE E +R++ + A+ L Q+++
Sbjct: 499 VQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEED 558
Query: 513 NEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQ-----ERTLALKLQEQEQLLKEGFQK 567
+ +E+ + +E L+++ + E RV+ +KE+ E+ A ++ E+ +E +
Sbjct: 559 KRRRLEEVKLKREERLRKVLQARE--RVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAE 616
Query: 568 ESRIMKNEIQDLQTKMRRRK 587
E K + ++ RRK
Sbjct: 617 EKAKKKAAAKKMEEVEARRK 636
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 53.9 bits (128), Expect = 4e-07
Identities = 51/256 (19%), Positives = 121/256 (47%), Gaps = 31/256 (12%)
Query: 350 LQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSA 409
LQE L L +SE+ I++ + KEL +LE+ + +Q +A +D
Sbjct: 287 LQEKLQLV-ESEKSEIQLNV------------KELKRKLERAKLLLPQQQLQAEADHLGK 333
Query: 410 LLQVIFSPLEEEVKAG-------------IYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQ 456
LQ + + L+ +V+ ++ + + + +K+Q+ ++K E+ K +
Sbjct: 334 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 393
Query: 457 AEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQM 516
EE ++ + + + + ++ + EKE+++ + + + L+E + E++
Sbjct: 394 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 453
Query: 517 MEQKERSYQEHLKQLTEKMENDRVQLLKEQE--RTLALKLQEQEQLL---KEGFQKESRI 571
EQ+E+ +E + EK + ++ +++E R K++EQE+ + +E ++ +I
Sbjct: 454 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKI 513
Query: 572 MKNEIQDLQTKMRRRK 587
+ E + Q +M R++
Sbjct: 514 REEEKRQEQEEMWRQE 529
Score = 47.0 bits (110), Expect = 5e-05
Identities = 27/130 (20%), Positives = 69/130 (53%), Gaps = 2/130 (1%)
Query: 438 QKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAE 497
+K+++ ++K E+ K + EE+ Q + + + + ++ + E+E+++ + K
Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644
Query: 498 SAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQ 557
+ + +E R+ E+MM+++E E +++ E + +++Q +E+ R K+ EQ
Sbjct: 645 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE--QEEKMQEQEEKMRRQEEKMWEQ 702
Query: 558 EQLLKEGFQK 567
E L++ +K
Sbjct: 703 EVRLRQQEEK 712
Score = 46.2 bits (108), Expect = 8e-05
Identities = 45/212 (21%), Positives = 100/212 (47%), Gaps = 23/212 (10%)
Query: 381 QKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEV---KAGIYSKPGGYRLFV 437
Q+E + EK R++ +Q QE + + + +EE+ K I+ + R
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE------QEEIWRQKEKIHEQEEKIRKQE 556
Query: 438 QKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAE 497
+K+ ++K +++ K + EE + + + I + ++ + E+E+ + + K
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616
Query: 498 SAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQ--LLKEQERTLALKLQ 555
+ +E ++ E+ M ++E +E K++ E+ E R Q +++EQE K+
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE----KMW 672
Query: 556 EQEQLLKEGFQKESRIMKNEIQDLQTKMRRRK 587
EQE+ + E + ++Q+ + KMRR++
Sbjct: 673 EQEEKMCE--------QEEKMQEQEEKMRRQE 696
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/152 (20%), Positives = 85/152 (55%), Gaps = 7/152 (4%)
Query: 438 QKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAE 497
+K++ ++ +E+ K + EE++ + + + + + ++ ++EK E E+++ +
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 498 S--AQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQ 555
+ AKM ++ ++ EQ E+K R +E + + EK+ +++ ++ +E++R ++
Sbjct: 470 EKRQEQEAKMWRQEEKIREQ--EEKIREQEEKMWRQEEKI-HEQEKIREEEKRQEQEEMW 526
Query: 556 EQEQLLKEGFQKESRIMKNEIQDLQTKMRRRK 587
QE+ ++E Q+E K +I + + K+R+++
Sbjct: 527 RQEEKIRE--QEEIWRQKEKIHEQEEKIRKQE 556
Score = 41.2 bits (95), Expect = 0.003
Identities = 37/162 (22%), Positives = 83/162 (51%), Gaps = 26/162 (16%)
Query: 438 QKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAE 497
+K+++ +K+ +E + Q E+I + K +E Q ++ ++EK E E+++ E
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-------QEEKMWRQEEKIHEQEKIREE 516
Query: 498 SAQASAKMLQEMQRKNEQMMEQKER-SYQEHLKQLTEKMENDRVQLLKEQERTLAL--KL 554
E +++ E+M Q+E+ QE + + EK+ ++ K++E+ K+
Sbjct: 517 ----------EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKM 566
Query: 555 QEQEQLLKEGFQK----ESRIMKNE--IQDLQTKMRRRKACT 590
+QE+ ++E +K E +I + E I++ + K+R ++ T
Sbjct: 567 HDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMT 608
Score = 38.5 bits (88), Expect = 0.018
Identities = 32/157 (20%), Positives = 81/157 (51%), Gaps = 10/157 (6%)
Query: 438 QKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAE 497
+K++ ++ +E+ K + EE + K +E + Q ++ + E+EK E E
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ--EEKRQEEEKIREQEKRQEQEAKMWR 481
Query: 498 SAQASAKMLQEMQRKNEQMMEQKERSY-QEHLKQLTEKMENDRV----QLLKEQERTLAL 552
+ + ++++ + E+M Q+E+ + QE +++ ++ E + + + ++EQE
Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541
Query: 553 K--LQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRK 587
K + EQE+ +++ +K R + ++ D + K+R ++
Sbjct: 542 KEKIHEQEEKIRKQEEKMWR-QEEKMHDQEEKIREQE 577
Score = 36.2 bits (82), Expect = 0.087
Identities = 24/101 (23%), Positives = 51/101 (50%), Gaps = 7/101 (6%)
Query: 438 QKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEI-EVERVKA 496
+K+ + ++K E+ K + EE ++ K + I + ++ + E+E+++ E E
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 679
Query: 497 ESAQASAKMLQEMQRKNEQMMEQK------ERSYQEHLKQL 531
E + + ++M+R+ E+M EQ+ E QEH + L
Sbjct: 680 EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 32.7 bits (73), Expect = 0.96
Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 25/105 (23%)
Query: 438 QKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAE 497
+K+++ +KK E+ K + EE++Q ++EK E E E
Sbjct: 641 EKIREQEKKIREQEEKIREQEEMMQ--------------------EQEEKMWEQEEKMCE 680
Query: 498 SAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQL 542
+ + ++M+R+ E+M EQ+ R L+Q EKM+ + L
Sbjct: 681 QEEKMQEQEEKMRRQEEKMWEQEVR-----LRQQEEKMQEHQEHL 720
Score = 32.0 bits (71), Expect = 1.6
Identities = 34/192 (17%), Positives = 83/192 (43%), Gaps = 8/192 (4%)
Query: 398 QNQEASSDRCSALLQVI--FSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGI 455
Q+QEA A + I + + E++ +Y + + +DL + ++ +
Sbjct: 177 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 236
Query: 456 QAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQ 515
+ E+ L K+ I + LT++ + +E + K ++ Q
Sbjct: 237 ELEQALSAVATQKKKADRYI----EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQ 292
Query: 516 MMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNE 575
++E ++ Q ++K+L K+E ++ L ++Q + A L ++ Q + Q +++ +NE
Sbjct: 293 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ--AQVEENE 350
Query: 576 IQDLQTKMRRRK 587
+ + + + K
Sbjct: 351 LWNRLNQQQEEK 362
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 53.5 bits (127), Expect = 5e-07
Identities = 72/312 (23%), Positives = 144/312 (46%), Gaps = 58/312 (18%)
Query: 321 QIENSAAVQKAIAHYEQQMGQKVQLPTET---LQELLDLHRDSEREAIEVF------IRS 371
+++ A Q A AH ++M Q V + + L+E L ++ E ++ ++S
Sbjct: 653 KLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKS 712
Query: 372 SFKDVDHLFQ----KELAAQLEK---KRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKA 424
+ + L K++ Q+EK ++D+ K +E + L+QV + EEE+ A
Sbjct: 713 EVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLE---TGLIQV--ATKEEELNA 767
Query: 425 -------------GIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYL---KSK 468
+ +K F +++LKK +E+ K EE+L+ L +K
Sbjct: 768 IRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANK 827
Query: 469 E-----SMTDAILQTDQTLTEKEKEIEVERVKAESAQA----SAKMLQEMQRKNEQMMEQ 519
E S+T + + L KE+++ + E + + K LQ++Q +NE +
Sbjct: 828 EKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 887
Query: 520 KERSYQEHLKQLTEKMENDRVQL-LKEQE---RTLALKLQEQE-------QLLKEGFQKE 568
+ Q +LK+ + + + +++ LKE+E + L L+E+E QLL++ Q E
Sbjct: 888 VQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQD-VQDE 946
Query: 569 SRIMKNEIQDLQ 580
+++ K++I+ L+
Sbjct: 947 NKLFKSQIEQLK 958
Score = 41.6 bits (96), Expect = 0.002
Identities = 63/310 (20%), Positives = 127/310 (40%), Gaps = 61/310 (19%)
Query: 328 VQKAIAHYEQQMG--------QKVQLPTETLQELLDLHRDSER---EAIEVFIRSSFKDV 376
++ IAH +Q+ G QL ++ EL L +D R E E + ++V
Sbjct: 415 MEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEV 474
Query: 377 DHLFQKELAAQLEKKRDDFCKQNQEASS---------DRCSALLQVIFSPLEEEVKAGIY 427
++ A QL+ + + ++ +E S + LQ F E EV++ ++
Sbjct: 475 QKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQS-LH 533
Query: 428 SKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKS-------------------- 467
SK + Q+L+ + E +K + EE LQ ++
Sbjct: 534 SKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIA 593
Query: 468 --------KESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQ--------EMQR 511
E + I + D+ + + E + ER + S + K +Q E+Q+
Sbjct: 594 AQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQK 653
Query: 512 KNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRI 571
EQ +++ Q + +++D+++LL+EQ + E+ ++L + +++
Sbjct: 654 LQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND----QNKA 709
Query: 572 MKNEIQDLQT 581
+K+E+Q LQT
Sbjct: 710 LKSEVQKLQT 719
Score = 39.7 bits (91), Expect = 0.008
Identities = 53/219 (24%), Positives = 94/219 (42%), Gaps = 47/219 (21%)
Query: 412 QVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAE-----EILQTYLK 466
QV F+ L EE+K I+ K G + V++L + + K +Q + LQ LK
Sbjct: 789 QVSFASLVEELKKVIHEKDGKIKS-VEELLEAELLKVANKEKTVQLSITSKVQELQNLLK 847
Query: 467 SKESMTDAILQTDQTLTEKEKEI------------EVERVKA---ESAQ------ASAKM 505
KE + + L EKEK++ E E +KA E AQ +SA
Sbjct: 848 GKEEQMNTM---KAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQ 904
Query: 506 LQEMQ----------RKNEQMMEQKERSYQEHLKQLTE-----KMENDRVQLLKEQERTL 550
+E++ ++ E M++++E + L + K+ +++ LK+Q
Sbjct: 905 FEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQ 964
Query: 551 ALKLQEQEQLLKEGFQKESRI--MKNEIQDLQTKMRRRK 587
A E+LLK ++E I + NE+ L+ + ++
Sbjct: 965 ASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQR 1003
Score = 35.8 bits (81), Expect = 0.11
Identities = 48/218 (22%), Positives = 96/218 (44%), Gaps = 31/218 (14%)
Query: 353 LLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQ 412
L DL ++E +++ ++V KE ++ + + + + +E R A+L+
Sbjct: 874 LQDLQEENES------LKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLK 927
Query: 413 VIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMT 472
S L + + + +LF +++ LK++ Y++ EE+L+
Sbjct: 928 ERESDLSSKTQL-LQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKV--------- 977
Query: 473 DAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLT 532
++E+EKEI + +S + + E QRK + +K E L T
Sbjct: 978 ---------ISEREKEISGLWNELDSLKDAV----EHQRKKNNDLREKNWEAMEALAS-T 1023
Query: 533 EKMENDRV-QLLKEQERTLALKLQEQEQLLKEGFQKES 569
EKM D+V + KE+++ + E +++LK+ F K S
Sbjct: 1024 EKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVS 1061
Score = 35.0 bits (79), Expect = 0.19
Identities = 36/194 (18%), Positives = 82/194 (42%), Gaps = 23/194 (11%)
Query: 328 VQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQ 387
+Q+++ E + KV +T++++ SE+E +RS KD+++L ++ +
Sbjct: 1130 LQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER--LRSENKDIENLRREREHLE 1187
Query: 388 LEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKY 447
+E ++ + + A L + L E Q+ ++K
Sbjct: 1188 MELEKAEMERSTYVTEVRELKAQLNETLTKLRTE-------------------QNERQKV 1228
Query: 448 YEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQ 507
+ K Q+ E++Q+ + T I +D ++ + + E E + Q ++ Q
Sbjct: 1229 AGDLHKAQQSLELIQSKIVKAAGDTTVIENSD--VSPETESSEKETMSVSLNQTVTQLQQ 1286
Query: 508 EMQRKNEQMMEQKE 521
+Q N+Q+ ++KE
Sbjct: 1287 LLQAVNQQLTKEKE 1300
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 53.5 bits (127), Expect = 5e-07
Identities = 73/302 (24%), Positives = 135/302 (44%), Gaps = 32/302 (10%)
Query: 321 QIENSAAVQKAIAHYEQQMGQKVQLPT------------ETLQELLDLHRDSEREAIEVF 368
+IE +A KA + + G++++L ETL++ L + ++ EA E
Sbjct: 762 EIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEA 821
Query: 369 I---RSSFKDVDHLFQKE-----LAAQLEKKRDDFCKQNQE-ASSDRCSALLQVIFSPLE 419
+ RS + V+ L QKE L++ LEK R++ + D L LE
Sbjct: 822 VSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLE 881
Query: 420 EEVKAGIYSKPGGYRLFVQKLQD---LKKKYYEEPR-KGIQAEEILQTYLKSKESMTDAI 475
++ A I G + K+ D LK++ EE + K +A E KS E MT
Sbjct: 882 NDI-AEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKA 940
Query: 476 LQTDQTLTEK--EKEIEVERVKAE---SAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQ 530
Q+ Q +K E++ E+ER ++ + S QE++ + E+ + + ++E L+
Sbjct: 941 EQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQN 1000
Query: 531 LTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKACT 590
L + + + +L +E L LQE E+L K+ + ++ + + +M + K T
Sbjct: 1001 LQKTLLDTEDKLKGAREENSGL-LQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTET 1059
Query: 591 IS 592
++
Sbjct: 1060 LA 1061
Score = 41.2 bits (95), Expect = 0.003
Identities = 63/276 (22%), Positives = 123/276 (44%), Gaps = 38/276 (13%)
Query: 313 ENAVLALAQIENSAA-VQKAIAHYEQQ---MGQKVQLPTETLQEL-LDLHRDSEREAIEV 367
E + A ++EN A + K Q M +++L ++EL L L + +E +
Sbjct: 871 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS--- 927
Query: 368 FIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIY 427
F++ S +D + + E+ + + K+++E + L+ S LE++++
Sbjct: 928 FLQKSIED--------MTVKAEQSQQEAAKKHEEEKKE-----LERKLSDLEKKMETSH- 973
Query: 428 SKPGGYRLFVQKLQDLKKKYYEEPRKG-IQAEEILQTYLKSKESMTDAILQTDQTLTEKE 486
+ Q+LK +Y + + EEILQ K+ D + + +
Sbjct: 974 ----------NQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLL 1023
Query: 487 KEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQ--EHLKQLTEKMENDRVQLLK 544
+E+E R +A+ A+A A+ ++ + EQM ++K + E KQ K++N+ + LK
Sbjct: 1024 QELEELRKQADKAKA-AQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNE-LDTLK 1081
Query: 545 EQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQ 580
E +L + ++LL QK K EI+ L+
Sbjct: 1082 ENNLKNVEELNKSKELLTVENQKMEEFRK-EIETLK 1116
Score = 38.1 bits (87), Expect = 0.023
Identities = 78/329 (23%), Positives = 143/329 (43%), Gaps = 45/329 (13%)
Query: 245 RKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTYVNAI 304
RKL+ LEK E Q++ Y + S+TKT I L++L T ++
Sbjct: 960 RKLSDLEKKM--ETSHNQCQELK--ARYERATSETKTKHEEI------LQNLQKTLLDTE 1009
Query: 305 SSGDLPCMENAVLA--LAQIENSAAVQKAIAHYE---QQMGQKVQLPTETLQELLDLHRD 359
EN+ L L ++ A KA E Q M Q + TETL L D +
Sbjct: 1010 DKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQT 1069
Query: 360 SER--EAIEVFIRSSFKDVDHLFQ-KELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFS 416
+ + ++ ++ K+V+ L + KEL +K ++F K+ E + Q + +
Sbjct: 1070 NAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEI-ETLKQAAAQKSQQLSA 1128
Query: 417 PLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKS----KESMT 472
EE VK + + G R V Q L+++ + ++ ++ ++K K S+
Sbjct: 1129 LQEENVK--LAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQ 1186
Query: 473 DAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLT 532
+I T LTEK+ E+E + +NE + + E + + L +
Sbjct: 1187 KSISITSALLTEKDAELE-------------------KLRNEVTVLRGENASAKSLHSVV 1227
Query: 533 EKMENDRVQLLKEQERTLALKLQEQEQLL 561
+ +E+D+V+ L+ + + L L+L+E ++ L
Sbjct: 1228 QTLESDKVK-LELKVKNLELQLKENKRQL 1255
Score = 33.9 bits (76), Expect = 0.43
Identities = 53/227 (23%), Positives = 95/227 (41%), Gaps = 29/227 (12%)
Query: 348 ETLQELLDLH-RDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDR 406
+TL +L + + E E ++ K +D+ F +L A EK D ++ASS+
Sbjct: 684 DTLNKLQEAEIKVKELEVLQAKCNEQTKVIDN-FTSQLKATEEKLLD--LDALRKASSEG 740
Query: 407 CSAL--LQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTY 464
S + L+ E+++K L ++K + K + +Q E+ T
Sbjct: 741 KSEMKKLRQQLEAAEKQIK----------HLEIEKNAESSKA--SSITRELQGRELKLTN 788
Query: 465 LKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSY 524
L+ S + Q +TL EKE+++ + K A A +Q ++ + QKE +
Sbjct: 789 LQENLS---EVSQVKETL---EKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQF 842
Query: 525 QEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRI 571
L + EN L + E K + +EQL+K + E+ I
Sbjct: 843 NMLSSDLEKLREN-----LADMEAKFREKDEREEQLIKAKEKLENDI 884
Score = 30.8 bits (68), Expect = 3.7
Identities = 54/255 (21%), Positives = 116/255 (45%), Gaps = 31/255 (12%)
Query: 349 TLQELLDLHR-DSEREAIEVFIRSSFKDVDHLFQKEL-----AAQLEKKRDDFCKQNQEA 402
+LQE L++ R D +RE ++ F + QKE+ A + K ++ K E
Sbjct: 508 SLQEKLEVTRTDHQREITS--LKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEH 565
Query: 403 SSDRCSALLQVIFSPLE----------EEVKA----GIYSKPGGYRLFVQKLQDLKKKYY 448
++ S ++ + S LE EE+K G+ ++ + +++ ++ Y
Sbjct: 566 ANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQ 625
Query: 449 EEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQE 508
E + +Q ++ + +KE L+ KEKE +E ++++ +A + L E
Sbjct: 626 HEI-ENLQNQQDSERAAHAKEMEA---LRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVE 681
Query: 509 MQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKE 568
M+ ++ E + + + L+ L K N++ +++ T LK E++ L + +K
Sbjct: 682 MEDTLNKLQEAEIK--VKELEVLQAKC-NEQTKVI--DNFTSQLKATEEKLLDLDALRKA 736
Query: 569 SRIMKNEIQDLQTKM 583
S K+E++ L+ ++
Sbjct: 737 SSEGKSEMKKLRQQL 751
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 53.5 bits (127), Expect = 5e-07
Identities = 73/302 (24%), Positives = 135/302 (44%), Gaps = 32/302 (10%)
Query: 321 QIENSAAVQKAIAHYEQQMGQKVQLPT------------ETLQELLDLHRDSEREAIEVF 368
+IE +A KA + + G++++L ETL++ L + ++ EA E
Sbjct: 797 EIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEA 856
Query: 369 I---RSSFKDVDHLFQKE-----LAAQLEKKRDDFCKQNQE-ASSDRCSALLQVIFSPLE 419
+ RS + V+ L QKE L++ LEK R++ + D L LE
Sbjct: 857 VSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLE 916
Query: 420 EEVKAGIYSKPGGYRLFVQKLQD---LKKKYYEEPR-KGIQAEEILQTYLKSKESMTDAI 475
++ A I G + K+ D LK++ EE + K +A E KS E MT
Sbjct: 917 NDI-AEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKA 975
Query: 476 LQTDQTLTEK--EKEIEVERVKAE---SAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQ 530
Q+ Q +K E++ E+ER ++ + S QE++ + E+ + + ++E L+
Sbjct: 976 EQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQN 1035
Query: 531 LTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKACT 590
L + + + +L +E L LQE E+L K+ + ++ + + +M + K T
Sbjct: 1036 LQKTLLDTEDKLKGAREENSGL-LQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTET 1094
Query: 591 IS 592
++
Sbjct: 1095 LA 1096
Score = 41.2 bits (95), Expect = 0.003
Identities = 63/276 (22%), Positives = 123/276 (44%), Gaps = 38/276 (13%)
Query: 313 ENAVLALAQIENSAA-VQKAIAHYEQQ---MGQKVQLPTETLQEL-LDLHRDSEREAIEV 367
E + A ++EN A + K Q M +++L ++EL L L + +E +
Sbjct: 906 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS--- 962
Query: 368 FIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIY 427
F++ S +D + + E+ + + K+++E + L+ S LE++++
Sbjct: 963 FLQKSIED--------MTVKAEQSQQEAAKKHEEEKKE-----LERKLSDLEKKMETSH- 1008
Query: 428 SKPGGYRLFVQKLQDLKKKYYEEPRKG-IQAEEILQTYLKSKESMTDAILQTDQTLTEKE 486
+ Q+LK +Y + + EEILQ K+ D + + +
Sbjct: 1009 ----------NQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLL 1058
Query: 487 KEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQ--EHLKQLTEKMENDRVQLLK 544
+E+E R +A+ A+A A+ ++ + EQM ++K + E KQ K++N+ + LK
Sbjct: 1059 QELEELRKQADKAKA-AQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNE-LDTLK 1116
Query: 545 EQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQ 580
E +L + ++LL QK K EI+ L+
Sbjct: 1117 ENNLKNVEELNKSKELLTVENQKMEEFRK-EIETLK 1151
Score = 38.1 bits (87), Expect = 0.023
Identities = 78/329 (23%), Positives = 143/329 (43%), Gaps = 45/329 (13%)
Query: 245 RKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTYVNAI 304
RKL+ LEK E Q++ Y + S+TKT I L++L T ++
Sbjct: 995 RKLSDLEKKM--ETSHNQCQELK--ARYERATSETKTKHEEI------LQNLQKTLLDTE 1044
Query: 305 SSGDLPCMENAVLA--LAQIENSAAVQKAIAHYE---QQMGQKVQLPTETLQELLDLHRD 359
EN+ L L ++ A KA E Q M Q + TETL L D +
Sbjct: 1045 DKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQT 1104
Query: 360 SER--EAIEVFIRSSFKDVDHLFQ-KELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFS 416
+ + ++ ++ K+V+ L + KEL +K ++F K+ E + Q + +
Sbjct: 1105 NAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEI-ETLKQAAAQKSQQLSA 1163
Query: 417 PLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKS----KESMT 472
EE VK + + G R V Q L+++ + ++ ++ ++K K S+
Sbjct: 1164 LQEENVK--LAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQ 1221
Query: 473 DAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLT 532
+I T LTEK+ E+E + +NE + + E + + L +
Sbjct: 1222 KSISITSALLTEKDAELE-------------------KLRNEVTVLRGENASAKSLHSVV 1262
Query: 533 EKMENDRVQLLKEQERTLALKLQEQEQLL 561
+ +E+D+V+ L+ + + L L+L+E ++ L
Sbjct: 1263 QTLESDKVK-LELKVKNLELQLKENKRQL 1290
Score = 33.9 bits (76), Expect = 0.43
Identities = 53/227 (23%), Positives = 95/227 (41%), Gaps = 29/227 (12%)
Query: 348 ETLQELLDLH-RDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDR 406
+TL +L + + E E ++ K +D+ F +L A EK D ++ASS+
Sbjct: 719 DTLNKLQEAEIKVKELEVLQAKCNEQTKVIDN-FTSQLKATEEKLLD--LDALRKASSEG 775
Query: 407 CSAL--LQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTY 464
S + L+ E+++K L ++K + K + +Q E+ T
Sbjct: 776 KSEMKKLRQQLEAAEKQIK----------HLEIEKNAESSKA--SSITRELQGRELKLTN 823
Query: 465 LKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSY 524
L+ S + Q +TL EKE+++ + K A A +Q ++ + QKE +
Sbjct: 824 LQENLS---EVSQVKETL---EKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQF 877
Query: 525 QEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRI 571
L + EN L + E K + +EQL+K + E+ I
Sbjct: 878 NMLSSDLEKLREN-----LADMEAKFREKDEREEQLIKAKEKLENDI 919
Score = 30.8 bits (68), Expect = 3.7
Identities = 54/255 (21%), Positives = 116/255 (45%), Gaps = 31/255 (12%)
Query: 349 TLQELLDLHR-DSEREAIEVFIRSSFKDVDHLFQKEL-----AAQLEKKRDDFCKQNQEA 402
+LQE L++ R D +RE ++ F + QKE+ A + K ++ K E
Sbjct: 543 SLQEKLEVTRTDHQREITS--LKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEH 600
Query: 403 SSDRCSALLQVIFSPLE----------EEVKA----GIYSKPGGYRLFVQKLQDLKKKYY 448
++ S ++ + S LE EE+K G+ ++ + +++ ++ Y
Sbjct: 601 ANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQ 660
Query: 449 EEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQE 508
E + +Q ++ + +KE L+ KEKE +E ++++ +A + L E
Sbjct: 661 HEI-ENLQNQQDSERAAHAKEMEA---LRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVE 716
Query: 509 MQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKE 568
M+ ++ E + + + L+ L K N++ +++ T LK E++ L + +K
Sbjct: 717 MEDTLNKLQEAEIK--VKELEVLQAKC-NEQTKVI--DNFTSQLKATEEKLLDLDALRKA 771
Query: 569 SRIMKNEIQDLQTKM 583
S K+E++ L+ ++
Sbjct: 772 SSEGKSEMKKLRQQL 786
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 53.5 bits (127), Expect = 5e-07
Identities = 92/391 (23%), Positives = 152/391 (38%), Gaps = 66/391 (16%)
Query: 243 HRRKLAQLEKLQ----DEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVL 298
H +++++LEK Q +E+L+ E +QQ++ K ++ ES L
Sbjct: 1719 HDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRAL 1778
Query: 299 -TYVNAISSGDLPCMENAVL---ALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELL 354
+ V +S E + LAQ + A + + EQ +K++L LQ+ L
Sbjct: 1779 QSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQEL 1838
Query: 355 D--------LHRD---------SEREAIEVFIRSSFKDVDHL-FQKELAAQLEKKRDDFC 396
D LH D +REA+ DHL K+ K +D
Sbjct: 1839 DQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLL 1898
Query: 397 KQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQ 456
+ D + EEE K Q+LQ L+ + E K +Q
Sbjct: 1899 SEQTRLQKDISEWANRFEDCQKEEETKQ-------------QQLQVLQNEIEENKLKLVQ 1945
Query: 457 AEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERV-----------KAESAQASAKM 505
E + Q K +ES + + TL E++ ++E E K +A+ +
Sbjct: 1946 QEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRT 2005
Query: 506 LQEMQR---KNEQMMEQKERSYQEHLKQLTEK--------MENDRVQ----LLKEQERTL 550
LQE +R E+ + Q +R E +QL EK E D ++ LL+ Q T
Sbjct: 2006 LQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTE 2065
Query: 551 ALKLQEQEQLLKEGFQ-KESRIMKNEIQDLQ 580
K ++Q LKE + + S++ KN ++ Q
Sbjct: 2066 RKKAEKQVASLKEALKIQRSQLEKNLLEQKQ 2096
Score = 41.2 bits (95), Expect = 0.003
Identities = 55/266 (20%), Positives = 109/266 (40%), Gaps = 24/266 (9%)
Query: 337 QQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSS-------------FKDVDHLFQKE 383
+Q+ ++QL + QE LDL E++ E+ + KD H K
Sbjct: 496 KQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKA 555
Query: 384 LAAQLEKKRDDFCKQNQEASSDRCSALLQVI-----FSPLEEEVKAGIYSKPGGYRLFVQ 438
+ E++ D KQ Q+ S L ++ LEE++ G + + ++
Sbjct: 556 QKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLE 615
Query: 439 KLQDLKKKYYEEPR-KGIQAEEILQTYLKSKESMTDAILQTDQTLTEKE-KEIEVERVKA 496
+ ++Y + + QA+ + KE++ + + +Q + E ++ E ++
Sbjct: 616 GVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRK 675
Query: 497 ESAQASAKMLQEMQRKNEQMMEQKE--RSYQEHLKQLTEKMENDRVQLLKEQERTLALKL 554
E A+ + LQE N + + + +Y+ L+ + + QL +E E+ L
Sbjct: 676 ELAELESA-LQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQ 734
Query: 555 QEQEQLLKEGFQKESRIMKNEIQDLQ 580
EQ L E +KE + +KN + Q
Sbjct: 735 LEQSALQAE-LEKERQALKNALGKAQ 759
Score = 37.4 bits (85), Expect = 0.039
Identities = 53/283 (18%), Positives = 118/283 (41%), Gaps = 42/283 (14%)
Query: 305 SSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREA 364
+ GDL E A++E ++ A A+ ++ +KV T+ Q L + ER+A
Sbjct: 697 TQGDLSAYE------AELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQA 750
Query: 365 IEVFI-RSSFKDVDHLFQKELAAQLEKKRDD--FCKQNQEASSDRCSALLQVIFSPLE-- 419
++ + ++ F + EL A+L+ +DD KQ + + + ++ + P E
Sbjct: 751 LKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVA 810
Query: 420 ---EEVKAGIYSKPGGYRLFV------QKLQDLKKKYYE-------------------EP 451
+E++ + G + + L DL+K++ E +
Sbjct: 811 ARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQE 870
Query: 452 RKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAES--AQASAKMLQEM 509
+Q E+ L T + + L+ +++ E +++++ E Q + K ++E+
Sbjct: 871 EMALQQEK-LATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEI 929
Query: 510 QRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLAL 552
Q + +++ + + L QL E + +++ K QE+ L
Sbjct: 930 QGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGL 972
Score = 34.7 bits (78), Expect = 0.25
Identities = 43/204 (21%), Positives = 85/204 (41%), Gaps = 24/204 (11%)
Query: 397 KQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQD---LKKKYYEEPRK 453
++++ +DR A + S +E+ K + R +Q D L+++ E
Sbjct: 1431 RRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVN 1490
Query: 454 GIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKN 513
++A++ L++ + + ++ ++ L E K + + + + L E +K
Sbjct: 1491 LVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKL 1550
Query: 514 EQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKE--GFQKESRI 571
++ +E ER+ HL Q+LKE E L K E E+L + Q+E +
Sbjct: 1551 QKDIEMAERNEDHHL------------QVLKESEVLLQAKRAELEKLKSQVTSQQQEMAV 1598
Query: 572 M-------KNEIQDLQTKMRRRKA 588
+ K E+ LQ M + KA
Sbjct: 1599 LDRQLGHKKEELHLLQGSMVQAKA 1622
Score = 34.7 bits (78), Expect = 0.25
Identities = 48/230 (20%), Positives = 95/230 (41%), Gaps = 29/230 (12%)
Query: 348 ETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCK---------- 397
E + + L R+SE +E + + K+ H +KEL Q K K
Sbjct: 1947 EMMFQRLQKERESEESKLETS-KVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRT 2005
Query: 398 -QNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQD--------LKKKYY 448
Q +E + L L E + + + G L +QK D L+ ++
Sbjct: 2006 LQEEERWCESLEKTLSQTKRQLSEREQQLV--EKSGELLALQKEADSMRADFSLLRNQFL 2063
Query: 449 EEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQE 508
E +K + L+ LK + S Q ++ L E+++E + + + + A+ E
Sbjct: 2064 TERKKAEKQVASLKEALKIQRS------QLEKNLLEQKQENSCIQKEMATIELVAQDNHE 2117
Query: 509 MQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQL-LKEQERTLALKLQEQ 557
R+ + + Q + Y E KQ+ + + +R Q+ + + RTL +++++
Sbjct: 2118 RARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDE 2167
Score = 32.7 bits (73), Expect = 0.96
Identities = 51/282 (18%), Positives = 123/282 (43%), Gaps = 23/282 (8%)
Query: 320 AQIENSAAVQKAIAHYEQQM----GQKVQLPTETLQELLDLHRDSEREAIEVF--IRSSF 373
+Q + A + + + H ++++ G VQ + LQE L L E ++S
Sbjct: 1591 SQQQEMAVLDRQLGHKKEELHLLQGSMVQAKAD-LQEALRLGETEVTEKCNHIREVKSLL 1649
Query: 374 KDVDHLFQK-ELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGG 432
+++ FQK EL Q+ +++ QE + + LQV+ + + K + +
Sbjct: 1650 EELS--FQKGELNVQISERKTQLTLIKQEIEKEEEN--LQVVLRQMSKH-KTELKNILDM 1704
Query: 433 YRLFVQKLQDLKKKY------YEEPRKGIQAEEI-LQTYLKSKESMTDAILQTDQTLTEK 485
+L +LQ LK ++ E+ + + E++ L+ + + I Q L
Sbjct: 1705 LQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERD 1764
Query: 486 EKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKE 545
++EIE ++ + Q+ + L + + ++ + E+ + + L EN +++
Sbjct: 1765 KREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNL 1824
Query: 546 QERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRK 587
++ L ++ +QE + ++ + N+I +Q +++ ++
Sbjct: 1825 EKLELNVRKLQQE---LDQLNRDKLSLHNDISAMQQQLQEKR 1863
>gi|45505178 cancer antigen 1 [Homo sapiens]
Length = 641
Score = 52.4 bits (124), Expect = 1e-06
Identities = 37/142 (26%), Positives = 75/142 (52%), Gaps = 17/142 (11%)
Query: 458 EEILQTYLKSKESMTDAILQTDQTLTEKEKEIE-VERVKAESAQASAKMLQEMQRKNE-- 514
+E T ++ K L+ D+TL++KE+E+E ++++K E +A+A L ++R+ E
Sbjct: 285 QERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQ 344
Query: 515 -----------QMMEQKERSYQEHLKQLTEKM--ENDRVQLLKEQERTLALKLQEQ-EQL 560
Q +E++ ++ LK EK+ + +Q + E ERT +KLQ+Q ++
Sbjct: 345 EQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEV 404
Query: 561 LKEGFQKESRIMKNEIQDLQTK 582
E + + ++ ++E Q+ K
Sbjct: 405 KNENAKLKQQVARSEEQNYVPK 426
Score = 44.7 bits (104), Expect = 2e-04
Identities = 51/218 (23%), Positives = 100/218 (45%), Gaps = 30/218 (13%)
Query: 388 LEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKY 447
L+K + KQ +CS L LE+ VK + K ++F+ + LK+
Sbjct: 173 LQKLKHTNRKQEVRIQELQCSNLY------LEKRVKE-LQMKITKQQVFIDVINKLKENV 225
Query: 448 YE--EPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEV-----ERVKAESAQ 500
E E + I E+ K+ +++ + + T + L E + E+ +++KA
Sbjct: 226 EELIEDKYKIILEK--NDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVC 283
Query: 501 ASAKMLQEMQRKNEQMME--------QKERSYQEHLKQLTEKMEN------DRVQLLKEQ 546
+ + EMQ+KN+ + + K+ E L+QL +++E D ++ KE
Sbjct: 284 LQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEA 343
Query: 547 ERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMR 584
+ L LQE+ Q L++ +E + +K+ ++ L T++R
Sbjct: 344 QEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVR 381
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/194 (25%), Positives = 99/194 (51%), Gaps = 26/194 (13%)
Query: 412 QVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDL------KKKYYEEPRKGIQA--EEILQT 463
QV F+ L EE+K I+ K G + + L+ K+K ++ ++ I+A EEI
Sbjct: 789 QVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNV 848
Query: 464 YLKSKE--SMTDAILQTDQTLTEKEKEIEVERVKAESAQA----SAKMLQEMQRKNEQMM 517
L+ + S+T + + L KE+++ + E + + K LQ++Q +NE +
Sbjct: 849 QLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Query: 518 EQKERSYQEHLKQLTEKMENDRVQL-LKEQE---RTLALKLQEQE-------QLLKEGFQ 566
+ Q +LK+ + + + +++ LKE+E + L L+E+E QLL++ Q
Sbjct: 909 AHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQD-VQ 967
Query: 567 KESRIMKNEIQDLQ 580
E+++ K++I+ L+
Sbjct: 968 DENKLFKSQIEQLK 981
Score = 41.6 bits (96), Expect = 0.002
Identities = 63/310 (20%), Positives = 127/310 (40%), Gaps = 61/310 (19%)
Query: 328 VQKAIAHYEQQMG--------QKVQLPTETLQELLDLHRDSER---EAIEVFIRSSFKDV 376
++ IAH +Q+ G QL ++ EL L +D R E E + ++V
Sbjct: 415 MEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEV 474
Query: 377 DHLFQKELAAQLEKKRDDFCKQNQEASS---------DRCSALLQVIFSPLEEEVKAGIY 427
++ A QL+ + + ++ +E S + LQ F E EV++ ++
Sbjct: 475 QKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQS-LH 533
Query: 428 SKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKS-------------------- 467
SK + Q+L+ + E +K + EE LQ ++
Sbjct: 534 SKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIA 593
Query: 468 --------KESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQ--------EMQR 511
E + I + D+ + + E + ER + S + K +Q E+Q+
Sbjct: 594 AQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQK 653
Query: 512 KNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRI 571
EQ +++ Q + +++D+++LL+EQ + E+ ++L + +++
Sbjct: 654 LQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND----QNKA 709
Query: 572 MKNEIQDLQT 581
+K+E+Q LQT
Sbjct: 710 LKSEVQKLQT 719
Score = 38.1 bits (87), Expect = 0.023
Identities = 52/265 (19%), Positives = 116/265 (43%), Gaps = 40/265 (15%)
Query: 336 EQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRS-SFKDVDHLFQKELAAQLEK---- 390
+QQ+ Q++ E+ Q+ ++ + + ++ ++ + K F ++AAQ
Sbjct: 543 KQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLA 602
Query: 391 --------KRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQD 442
++D KQ +++ + L + EEE+K I + + VQKLQ
Sbjct: 603 EELHKVIAEKDKQIKQTEDSLASERDRL-----TSKEEELK-DIQNMNFLLKAEVQKLQA 656
Query: 443 LKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQAS 502
L E+ + E++ Q+ + + Q ++ K +E ++ + ++ ++
Sbjct: 657 LAN---EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSE 713
Query: 503 AKMLQEM--QRKNEQMMEQKERSYQEH---LKQLTEKMENDRVQLLKEQERTLALKLQEQ 557
+ LQ + ++ N+ ++EQ E+ QE LK + E +E +Q+ ++E A++
Sbjct: 714 VQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIR---- 769
Query: 558 EQLLKEGFQKESRIMKNEIQDLQTK 582
E+ + E+QDL+ K
Sbjct: 770 ---------TENSSLTKEVQDLKAK 785
Score = 36.6 bits (83), Expect = 0.067
Identities = 59/269 (21%), Positives = 118/269 (43%), Gaps = 50/269 (18%)
Query: 327 AVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSERE--AIEVFIRSSFKDVDHLFQ--- 381
A+++ I + + + Q++ + T +QEL +L + E + ++ + KD+ + +
Sbjct: 840 ALKEEIGNVQLEKAQQLSI-TSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQ 898
Query: 382 --KELAAQLEKKRDDFCKQN-QEASSDRCSALLQVIFSPLEEEVK----------AGIYS 428
+E L+ + + N +EASS L+++ E E+K + + S
Sbjct: 899 DLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSS 958
Query: 429 KP-------GGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQT 481
K +LF +++ LK++ Y++ EE+L+
Sbjct: 959 KTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKV------------------ 1000
Query: 482 LTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV- 540
++E+EKEI + +S + + E QRK + +K E L TEKM D+V
Sbjct: 1001 ISEREKEISGLWNELDSLKDAV----EHQRKKNNDLREKNWEAMEALAS-TEKMLQDKVN 1055
Query: 541 QLLKEQERTLALKLQEQEQLLKEGFQKES 569
+ KE+++ + E +++LK+ F K S
Sbjct: 1056 KTSKERQQQVEAVELEAKEVLKKLFPKVS 1084
Score = 35.0 bits (79), Expect = 0.19
Identities = 38/203 (18%), Positives = 85/203 (41%), Gaps = 13/203 (6%)
Query: 328 VQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQ 387
+Q+++ E + KV +T++++ SE+E +RS KD+++L ++ +
Sbjct: 1153 LQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER--LRSENKDIENLRREREHLE 1210
Query: 388 LEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKY 447
+E ++ + + LL + L++ + L Q + L K
Sbjct: 1211 MELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLR 1270
Query: 448 YEEPR---------KGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAES 498
E+ K Q+ E++Q+ + T I +D ++ + + E E +
Sbjct: 1271 TEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSD--VSPETESSEKETMSVSL 1328
Query: 499 AQASAKMLQEMQRKNEQMMEQKE 521
Q ++ Q +Q N+Q+ ++KE
Sbjct: 1329 NQTVTQLQQLLQAVNQQLTKEKE 1351
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/194 (25%), Positives = 99/194 (51%), Gaps = 26/194 (13%)
Query: 412 QVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDL------KKKYYEEPRKGIQA--EEILQT 463
QV F+ L EE+K I+ K G + + L+ K+K ++ ++ I+A EEI
Sbjct: 789 QVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNV 848
Query: 464 YLKSKE--SMTDAILQTDQTLTEKEKEIEVERVKAESAQA----SAKMLQEMQRKNEQMM 517
L+ + S+T + + L KE+++ + E + + K LQ++Q +NE +
Sbjct: 849 QLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Query: 518 EQKERSYQEHLKQLTEKMENDRVQL-LKEQE---RTLALKLQEQE-------QLLKEGFQ 566
+ Q +LK+ + + + +++ LKE+E + L L+E+E QLL++ Q
Sbjct: 909 AHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQD-VQ 967
Query: 567 KESRIMKNEIQDLQ 580
E+++ K++I+ L+
Sbjct: 968 DENKLFKSQIEQLK 981
Score = 41.6 bits (96), Expect = 0.002
Identities = 63/310 (20%), Positives = 127/310 (40%), Gaps = 61/310 (19%)
Query: 328 VQKAIAHYEQQMG--------QKVQLPTETLQELLDLHRDSER---EAIEVFIRSSFKDV 376
++ IAH +Q+ G QL ++ EL L +D R E E + ++V
Sbjct: 415 MEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEV 474
Query: 377 DHLFQKELAAQLEKKRDDFCKQNQEASS---------DRCSALLQVIFSPLEEEVKAGIY 427
++ A QL+ + + ++ +E S + LQ F E EV++ ++
Sbjct: 475 QKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQS-LH 533
Query: 428 SKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKS-------------------- 467
SK + Q+L+ + E +K + EE LQ ++
Sbjct: 534 SKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIA 593
Query: 468 --------KESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQ--------EMQR 511
E + I + D+ + + E + ER + S + K +Q E+Q+
Sbjct: 594 AQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQK 653
Query: 512 KNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRI 571
EQ +++ Q + +++D+++LL+EQ + E+ ++L + +++
Sbjct: 654 LQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND----QNKA 709
Query: 572 MKNEIQDLQT 581
+K+E+Q LQT
Sbjct: 710 LKSEVQKLQT 719
Score = 38.1 bits (87), Expect = 0.023
Identities = 52/265 (19%), Positives = 116/265 (43%), Gaps = 40/265 (15%)
Query: 336 EQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRS-SFKDVDHLFQKELAAQLEK---- 390
+QQ+ Q++ E+ Q+ ++ + + ++ ++ + K F ++AAQ
Sbjct: 543 KQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLA 602
Query: 391 --------KRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQD 442
++D KQ +++ + L + EEE+K I + + VQKLQ
Sbjct: 603 EELHKVIAEKDKQIKQTEDSLASERDRL-----TSKEEELK-DIQNMNFLLKAEVQKLQA 656
Query: 443 LKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQAS 502
L E+ + E++ Q+ + + Q ++ K +E ++ + ++ ++
Sbjct: 657 LAN---EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSE 713
Query: 503 AKMLQEM--QRKNEQMMEQKERSYQEH---LKQLTEKMENDRVQLLKEQERTLALKLQEQ 557
+ LQ + ++ N+ ++EQ E+ QE LK + E +E +Q+ ++E A++
Sbjct: 714 VQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIR---- 769
Query: 558 EQLLKEGFQKESRIMKNEIQDLQTK 582
E+ + E+QDL+ K
Sbjct: 770 ---------TENSSLTKEVQDLKAK 785
Score = 35.0 bits (79), Expect = 0.19
Identities = 36/194 (18%), Positives = 82/194 (42%), Gaps = 23/194 (11%)
Query: 328 VQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQ 387
+Q+++ E + KV +T++++ SE+E +RS KD+++L ++ +
Sbjct: 1124 LQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER--LRSENKDIENLRREREHLE 1181
Query: 388 LEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKY 447
+E ++ + + A L + L E Q+ ++K
Sbjct: 1182 MELEKAEMERSTYVTEVRELKAQLNETLTKLRTE-------------------QNERQKV 1222
Query: 448 YEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQ 507
+ K Q+ E++Q+ + T I +D ++ + + E E + Q ++ Q
Sbjct: 1223 AGDLHKAQQSLELIQSKIVKAAGDTTVIENSD--VSPETESSEKETMSVSLNQTVTQLQQ 1280
Query: 508 EMQRKNEQMMEQKE 521
+Q N+Q+ ++KE
Sbjct: 1281 LLQAVNQQLTKEKE 1294
Score = 31.2 bits (69), Expect = 2.8
Identities = 46/234 (19%), Positives = 102/234 (43%), Gaps = 44/234 (18%)
Query: 327 AVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSERE--AIEVFIRSSFKDVDHLFQ--- 381
A+++ I + + + Q++ + T +QEL +L + E + ++ + KD+ + +
Sbjct: 840 ALKEEIGNVQLEKAQQLSI-TSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQ 898
Query: 382 --KELAAQLEKKRDDFCKQN-QEASSDRCSALLQVIFSPLEEEVK----------AGIYS 428
+E L+ + + N +EASS L+++ E E+K + + S
Sbjct: 899 DLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSS 958
Query: 429 KP-------GGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQT 481
K +LF +++ LK++ Y++ EE+L+
Sbjct: 959 KTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKV------------------ 1000
Query: 482 LTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKM 535
++E+EKEI + +S + + + ++ + +Q +E E +E LK+L K+
Sbjct: 1001 ISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKV 1054
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/194 (25%), Positives = 99/194 (51%), Gaps = 26/194 (13%)
Query: 412 QVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDL------KKKYYEEPRKGIQA--EEILQT 463
QV F+ L EE+K I+ K G + + L+ K+K ++ ++ I+A EEI
Sbjct: 789 QVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNV 848
Query: 464 YLKSKE--SMTDAILQTDQTLTEKEKEIEVERVKAESAQA----SAKMLQEMQRKNEQMM 517
L+ + S+T + + L KE+++ + E + + K LQ++Q +NE +
Sbjct: 849 QLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Query: 518 EQKERSYQEHLKQLTEKMENDRVQL-LKEQE---RTLALKLQEQE-------QLLKEGFQ 566
+ Q +LK+ + + + +++ LKE+E + L L+E+E QLL++ Q
Sbjct: 909 AHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQD-VQ 967
Query: 567 KESRIMKNEIQDLQ 580
E+++ K++I+ L+
Sbjct: 968 DENKLFKSQIEQLK 981
Score = 41.6 bits (96), Expect = 0.002
Identities = 63/310 (20%), Positives = 127/310 (40%), Gaps = 61/310 (19%)
Query: 328 VQKAIAHYEQQMG--------QKVQLPTETLQELLDLHRDSER---EAIEVFIRSSFKDV 376
++ IAH +Q+ G QL ++ EL L +D R E E + ++V
Sbjct: 415 MEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEV 474
Query: 377 DHLFQKELAAQLEKKRDDFCKQNQEASS---------DRCSALLQVIFSPLEEEVKAGIY 427
++ A QL+ + + ++ +E S + LQ F E EV++ ++
Sbjct: 475 QKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQS-LH 533
Query: 428 SKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKS-------------------- 467
SK + Q+L+ + E +K + EE LQ ++
Sbjct: 534 SKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIA 593
Query: 468 --------KESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQ--------EMQR 511
E + I + D+ + + E + ER + S + K +Q E+Q+
Sbjct: 594 AQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQK 653
Query: 512 KNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRI 571
EQ +++ Q + +++D+++LL+EQ + E+ ++L + +++
Sbjct: 654 LQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND----QNKA 709
Query: 572 MKNEIQDLQT 581
+K+E+Q LQT
Sbjct: 710 LKSEVQKLQT 719
Score = 38.1 bits (87), Expect = 0.023
Identities = 52/265 (19%), Positives = 116/265 (43%), Gaps = 40/265 (15%)
Query: 336 EQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRS-SFKDVDHLFQKELAAQLEK---- 390
+QQ+ Q++ E+ Q+ ++ + + ++ ++ + K F ++AAQ
Sbjct: 543 KQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLA 602
Query: 391 --------KRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQD 442
++D KQ +++ + L + EEE+K I + + VQKLQ
Sbjct: 603 EELHKVIAEKDKQIKQTEDSLASERDRL-----TSKEEELK-DIQNMNFLLKAEVQKLQA 656
Query: 443 LKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQAS 502
L E+ + E++ Q+ + + Q ++ K +E ++ + ++ ++
Sbjct: 657 LAN---EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSE 713
Query: 503 AKMLQEM--QRKNEQMMEQKERSYQEH---LKQLTEKMENDRVQLLKEQERTLALKLQEQ 557
+ LQ + ++ N+ ++EQ E+ QE LK + E +E +Q+ ++E A++
Sbjct: 714 VQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIR---- 769
Query: 558 EQLLKEGFQKESRIMKNEIQDLQTK 582
E+ + E+QDL+ K
Sbjct: 770 ---------TENSSLTKEVQDLKAK 785
Score = 36.6 bits (83), Expect = 0.067
Identities = 59/269 (21%), Positives = 118/269 (43%), Gaps = 50/269 (18%)
Query: 327 AVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSERE--AIEVFIRSSFKDVDHLFQ--- 381
A+++ I + + + Q++ + T +QEL +L + E + ++ + KD+ + +
Sbjct: 840 ALKEEIGNVQLEKAQQLSI-TSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQ 898
Query: 382 --KELAAQLEKKRDDFCKQN-QEASSDRCSALLQVIFSPLEEEVK----------AGIYS 428
+E L+ + + N +EASS L+++ E E+K + + S
Sbjct: 899 DLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSS 958
Query: 429 KP-------GGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQT 481
K +LF +++ LK++ Y++ EE+L+
Sbjct: 959 KTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKV------------------ 1000
Query: 482 LTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV- 540
++E+EKEI + +S + + E QRK + +K E L TEKM D+V
Sbjct: 1001 ISEREKEISGLWNELDSLKDAV----EHQRKKNNDLREKNWEAMEALAS-TEKMLQDKVN 1055
Query: 541 QLLKEQERTLALKLQEQEQLLKEGFQKES 569
+ KE+++ + E +++LK+ F K S
Sbjct: 1056 KTSKERQQQVEAVELEAKEVLKKLFPKVS 1084
Score = 35.0 bits (79), Expect = 0.19
Identities = 38/203 (18%), Positives = 85/203 (41%), Gaps = 13/203 (6%)
Query: 328 VQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQ 387
+Q+++ E + KV +T++++ SE+E +RS KD+++L ++ +
Sbjct: 1153 LQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER--LRSENKDIENLRREREHLE 1210
Query: 388 LEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKY 447
+E ++ + + LL + L++ + L Q + L K
Sbjct: 1211 MELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLR 1270
Query: 448 YEEPR---------KGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAES 498
E+ K Q+ E++Q+ + T I +D ++ + + E E +
Sbjct: 1271 TEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSD--VSPETESSEKETMSVSL 1328
Query: 499 AQASAKMLQEMQRKNEQMMEQKE 521
Q ++ Q +Q N+Q+ ++KE
Sbjct: 1329 NQTVTQLQQLLQAVNQQLTKEKE 1351
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,183,534
Number of Sequences: 37866
Number of extensions: 963740
Number of successful extensions: 10511
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 233
Number of HSP's successfully gapped in prelim test: 884
Number of HSP's that attempted gapping in prelim test: 5330
Number of HSP's gapped (non-prelim): 3657
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.