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Search of human proteins with 166362735
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|166362735 erythrocyte membrane protein band 4.2 isoform 1
[Homo sapiens]
(721 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Ho... 1451 0.0
gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Ho... 1386 0.0
gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens] 379 e-105
gi|16445035 transglutaminase 7 [Homo sapiens] 374 e-103
gi|39777597 transglutaminase 2 isoform a [Homo sapiens] 372 e-103
gi|189458821 transglutaminase 3 precursor [Homo sapiens] 332 7e-91
gi|39777599 transglutaminase 2 isoform b [Homo sapiens] 324 2e-88
gi|148664232 transglutaminase 6 [Homo sapiens] 324 2e-88
gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens] 297 3e-80
gi|4507475 transglutaminase 1 [Homo sapiens] 267 3e-71
gi|156627577 transglutaminase 4 (prostate) [Homo sapiens] 266 7e-71
gi|119395709 coagulation factor XIII A1 subunit precursor [Homo ... 236 6e-62
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 33 0.93
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] 32 1.6
gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] 32 1.6
gi|30520346 A kinase (PRKA) anchor protein 14 isoform a [Homo sa... 32 1.6
gi|118498354 component of oligomeric golgi complex 4 [Homo sapiens] 32 2.7
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 31 3.5
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 31 4.6
gi|56549694 enabled homolog isoform a [Homo sapiens] 30 6.0
gi|39930375 enabled homolog isoform b [Homo sapiens] 30 6.0
gi|56682938 A kinase (PRKA) anchor protein 14 isoform b [Homo sa... 30 6.0
>gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Homo
sapiens]
Length = 721
Score = 1451 bits (3756), Expect = 0.0
Identities = 721/721 (100%), Positives = 721/721 (100%)
Query: 1 MGQGEPSQRSTGLAGLYAAPAASPVFIKGSGMDALGIKSCDFQAARNNEEHHTKALSSRR 60
MGQGEPSQRSTGLAGLYAAPAASPVFIKGSGMDALGIKSCDFQAARNNEEHHTKALSSRR
Sbjct: 1 MGQGEPSQRSTGLAGLYAAPAASPVFIKGSGMDALGIKSCDFQAARNNEEHHTKALSSRR 60
Query: 61 LFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQTGEQPSKINRTQATFPISSLGDRKWW 120
LFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQTGEQPSKINRTQATFPISSLGDRKWW
Sbjct: 61 LFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQTGEQPSKINRTQATFPISSLGDRKWW 120
Query: 121 SAVVEERDAQSWTISVTTPADAVIGHYSLLLQVSGRKQLLLGQFTLLFNPWNREDAVFLK 180
SAVVEERDAQSWTISVTTPADAVIGHYSLLLQVSGRKQLLLGQFTLLFNPWNREDAVFLK
Sbjct: 121 SAVVEERDAQSWTISVTTPADAVIGHYSLLLQVSGRKQLLLGQFTLLFNPWNREDAVFLK 180
Query: 181 NEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQFEGDVIDLSLRLLSKDKQVEKWSQPVH 240
NEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQFEGDVIDLSLRLLSKDKQVEKWSQPVH
Sbjct: 181 NEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQFEGDVIDLSLRLLSKDKQVEKWSQPVH 240
Query: 241 VARVLGALLHFLKEQRVLPTPQTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWV 300
VARVLGALLHFLKEQRVLPTPQTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWV
Sbjct: 241 VARVLGALLHFLKEQRVLPTPQTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWV 300
Query: 301 LAAVACTVLRCLGIPARVVTTFASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTST 360
LAAVACTVLRCLGIPARVVTTFASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTST
Sbjct: 301 LAAVACTVLRCLGIPARVVTTFASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTST 360
Query: 361 ECWMTRPALPQGYDGWQILHPSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAIN 420
ECWMTRPALPQGYDGWQILHPSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAIN
Sbjct: 361 ECWMTRPALPQGYDGWQILHPSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAIN 420
Query: 421 ASCVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLER 480
ASCVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLER
Sbjct: 421 ASCVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLER 480
Query: 481 VEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLA 540
VEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLA
Sbjct: 481 VEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLA 540
Query: 541 IGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATH 600
IGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATH
Sbjct: 541 IGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATH 600
Query: 601 SESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGL 660
SESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGL
Sbjct: 601 SESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGL 660
Query: 661 IHRERSYRFRSVWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTVVAPELS 720
IHRERSYRFRSVWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTVVAPELS
Sbjct: 661 IHRERSYRFRSVWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTVVAPELS 720
Query: 721 A 721
A
Sbjct: 721 A 721
>gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Homo
sapiens]
Length = 691
Score = 1386 bits (3588), Expect = 0.0
Identities = 688/688 (100%), Positives = 688/688 (100%)
Query: 34 ALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTA 93
ALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTA
Sbjct: 4 ALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTA 63
Query: 94 QTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQV 153
QTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQV
Sbjct: 64 QTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQV 123
Query: 154 SGRKQLLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQ 213
SGRKQLLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQ
Sbjct: 124 SGRKQLLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQ 183
Query: 214 FEGDVIDLSLRLLSKDKQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQATQEGALLN 273
FEGDVIDLSLRLLSKDKQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQATQEGALLN
Sbjct: 184 FEGDVIDLSLRLLSKDKQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQATQEGALLN 243
Query: 274 KRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTGGRLL 333
KRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTGGRLL
Sbjct: 244 KRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTGGRLL 303
Query: 334 IDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPNGGGVLGSC 393
IDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPNGGGVLGSC
Sbjct: 304 IDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPNGGGVLGSC 363
Query: 394 DLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVGNNISTKGV 453
DLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVGNNISTKGV
Sbjct: 364 DLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVGNNISTKGV 423
Query: 454 GSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLETASPLYLLLKAPS 513
GSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLETASPLYLLLKAPS
Sbjct: 424 GSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLETASPLYLLLKAPS 483
Query: 514 SLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKII 573
SLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKII
Sbjct: 484 SLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKII 543
Query: 574 TIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQP 633
TIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQP
Sbjct: 544 TIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQP 603
Query: 634 LTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENTMCAKFQFTPTHVGLQR 693
LTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENTMCAKFQFTPTHVGLQR
Sbjct: 604 LTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENTMCAKFQFTPTHVGLQR 663
Query: 694 LTVEVDCNMFQNLTNYKSVTVVAPELSA 721
LTVEVDCNMFQNLTNYKSVTVVAPELSA
Sbjct: 664 LTVEVDCNMFQNLTNYKSVTVVAPELSA 691
>gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens]
Length = 720
Score = 379 bits (973), Expect = e-105
Identities = 232/715 (32%), Positives = 357/715 (49%), Gaps = 38/715 (5%)
Query: 35 LGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQ 94
L + D Q++RNN HHT+ ++ L VRRGQ F + LYFR R+F P L + +
Sbjct: 5 LEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRN--RSFQPGLDNIIFVVE 62
Query: 95 TGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQVS 154
TG P T+A F ++ W A +E A S +S+ P A +G Y L + +
Sbjct: 63 TGPLPDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIHID 122
Query: 155 GRKQLL----LGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWD 210
+ + LG+F LLFNPW EDAV+L +E QR EY++N G IY G+ + I+ W+
Sbjct: 123 SFQGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWN 182
Query: 211 FGQFEGDVIDLSLRLLSKDKQVEK--------WSQPVHVARVLGALLHFLKEQRVLPTPQ 262
+GQFE +ID+ L+LL K + PV+V+RV+ A+++ + VL
Sbjct: 183 YGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNW 242
Query: 263 TQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTF 322
++ +GA + GSV IL+QW +PV GQ WV AAV CTV+RCLGIP RV+T F
Sbjct: 243 SENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNF 302
Query: 323 ASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPS 382
S T G L+IDEYY+ G G ++ IW F ECWM R LP Y GWQ+L +
Sbjct: 303 DSGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDAT 362
Query: 383 APNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTK 442
+ C VRA+KEG + L +F+ +NA C+ W + G + +T
Sbjct: 363 PQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSW-LVQGGKEQKLHQDTS 421
Query: 443 YVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLETA 502
VGN ISTK + SD +DIT+NYKY EGSLQE++V + ++ R R L+ +
Sbjct: 422 SVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPS 481
Query: 503 SPLYLLLKAPSSL---PLRGDAQISVTL--------------------VNHSEQEKAVQL 539
P L +P SL LR + V+L +N S Q K +++
Sbjct: 482 RPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKV 541
Query: 540 AIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMAT 599
+ Q++ ++G + W+ +TLS K + +S + + + +R++A+
Sbjct: 542 NLSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGE 601
Query: 600 HSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRG 659
S + I + P + I + A QPL+ V N L +EDCV+++ G G
Sbjct: 602 EKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSG 661
Query: 660 LIHRERSYRFRSVWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 714
L +++ + P++ + P G +++ + N F+++ Y++V V
Sbjct: 662 LFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYV 716
>gi|16445035 transglutaminase 7 [Homo sapiens]
Length = 710
Score = 374 bits (960), Expect = e-103
Identities = 229/701 (32%), Positives = 362/701 (51%), Gaps = 24/701 (3%)
Query: 35 LGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQ 94
L ++S D Q++RNN+EHHT+ + +RL VRRGQPF + L F P F + A+
Sbjct: 7 LRLESVDLQSSRNNKEHHTQEMGVKRLTVRRGQPFYLRLSFSRP---FQSQNDHITFVAE 63
Query: 95 TGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQVS 154
TG +PS++ T+ATF ++ + WSA D+ S +S+ TPA+AVIGHY+L +++S
Sbjct: 64 TGPKPSELLGTRATFFLTRVQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYTLKIEIS 123
Query: 155 -GRKQLL---LGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWD 210
G+ + LG F LLFNPW+ ED V+L +E EY++ G +Y G I + W+
Sbjct: 124 QGQGHSVTYPLGTFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERFITSWPWN 183
Query: 211 FGQFEGDVIDLSLRLLSKD--------KQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQ 262
+GQFE D+ID+ +L+K K + + V+V RV+ A+++ + VL
Sbjct: 184 YGQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDNGVLQGNW 243
Query: 263 TQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTF 322
+ +G + +GSV IL+QW G+PV GQ WV A+V CTV+RCLG+P RVV+ F
Sbjct: 244 GEDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVPTRVVSNF 303
Query: 323 ASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPS 382
SA L ID YY+ +R +IW F ECWM R LP GY+GWQ+L P+
Sbjct: 304 RSAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPGYNGWQVLDPT 363
Query: 383 APNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTK 442
L C V+A++EG + L ++A +NA V+W + E+ NT
Sbjct: 364 PQQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGDGQAQEILAHNTS 423
Query: 443 YVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLETA 502
+G ISTK VGSD+ + IT +YKYPEGS +E+ V + ++ + ++ + LE+
Sbjct: 424 SIGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLGPQRASLPFLDLLESG 483
Query: 503 ----SPLYLLLKAPSSLPLRGDAQISVTL-----VNHSEQEKAVQLAIGVQAVHYNGVLA 553
P L L D Q+ + + H + + QA+ + G
Sbjct: 484 GLRDQPAQLQLHLARIPEWGQDLQLLLRIQRVPDSTHPRGPIGLVVRFCAQALLHGGGTQ 543
Query: 554 AKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDI 613
WR + + L E + L +SN+ + +R++ +A E+ S +DI
Sbjct: 544 KPFWRHTVRMNLDFGKETQWPLLLPYSNYRNKLTDEKLIRVSGIAEVEETGRSMLVLKDI 603
Query: 614 AICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVW 673
+ PHL+I++ E+AE + L V+L N+L + C + + G GLI+ + + ++
Sbjct: 604 CLEPPHLSIEVSERAEVGKALRVHVTLTNTLMVALSSCTMVLEGSGLINGQIAKDLGTLV 663
Query: 674 PENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 714
+T+ + PT G ++L V + N + + YK + V
Sbjct: 664 AGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDIFV 704
>gi|39777597 transglutaminase 2 isoform a [Homo sapiens]
Length = 687
Score = 372 bits (954), Expect = e-103
Identities = 230/695 (33%), Positives = 352/695 (50%), Gaps = 26/695 (3%)
Query: 33 DALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALT 92
+ L ++ CD + N +HHT L +L VRRGQPF + L+F R + ++ + +
Sbjct: 3 EELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEG--RNYEASVDSLTFS 60
Query: 93 AQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQ 152
TG PS+ T+A FP+ + W+A V ++ + ++ +TTPA+A IG Y L L+
Sbjct: 61 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 120
Query: 153 VSGRKQ---LLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESW 209
S Q +LG F LLFN W DAV+L +E +R EY+L Q G IY G+A I+ W
Sbjct: 121 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 180
Query: 210 DFGQFEGDVIDLSLRLLSKD--------KQVEKWSQPVHVARVLGALLHFLKEQRVLPTP 261
+FGQFE ++D+ L LL + + + S PV+V RV+ +++ +Q VL
Sbjct: 181 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 240
Query: 262 QTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTT 321
+G GSV ILR+W + V GQ WV AAVACTVLRCLGIP RVVT
Sbjct: 241 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 300
Query: 322 FASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHP 381
+ SA LLI+ + NE G G+ IW F E WMTRP L GY+GWQ L P
Sbjct: 301 YNSAHDQNSNLLIEYFRNEFGEIQGDKSE-MIWNFHCWVESWMTRPDLQPGYEGWQALDP 359
Query: 382 SAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNT 441
+ C VPVRA+KEG L +FA +NA V W +DG++ + + +
Sbjct: 360 TPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRS 419
Query: 442 KYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLET 501
VG ISTK VG D EDIT YKYPEGS +E+E R EK+
Sbjct: 420 LIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEE--------- 470
Query: 502 ASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRK-K 560
+ + + ++ S+ + D + + N++ +E +L + + V YNG+L + K
Sbjct: 471 -TGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYL 529
Query: 561 LHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHL 620
L+L L EK + + + + + E+ +++ A+ N A+ D+ + P +
Sbjct: 530 LNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEI 589
Query: 621 AIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRS-VWPENTMC 679
I++ + +Q + L A VSLQN L +E C ++ G GL +++ V +
Sbjct: 590 KIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVK 649
Query: 680 AKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 714
+ P H+GL +L V + + + + +++V +
Sbjct: 650 VRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVII 684
>gi|189458821 transglutaminase 3 precursor [Homo sapiens]
Length = 693
Score = 332 bits (851), Expect = 7e-91
Identities = 212/698 (30%), Positives = 337/698 (48%), Gaps = 22/698 (3%)
Query: 32 MDALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVAL 91
M ALG++S ++Q A N + HHT SS+ L +RRGQ F +++ L + +++
Sbjct: 1 MAALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKG----LGSNERLEF 56
Query: 92 TAQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLL 151
TG PS+ T+A FP+S+ G WSAV++ + + TIS+++PA A IG Y++ L
Sbjct: 57 IVSTGPYPSESAMTKAVFPLSN-GSSGGWSAVLQASNGNTLTISISSPASAPIGRYTMAL 115
Query: 152 QV---SGRKQLLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAES 208
Q+ G + LG F LLFNPW D+VF+ N A+R EY+ G+I++G+ + I
Sbjct: 116 QIFSQGGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIG 175
Query: 209 WDFGQFEGDVIDLSLRLLSKD--------KQVEKWSQPVHVARVLGALLHFLKEQRVLPT 260
W+FGQFE D++ + L +L + V + P +V RVL A+++ + VL
Sbjct: 176 WNFGQFEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAG 235
Query: 261 PQTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVT 320
+ G GSV IL+ W PV GQ WV A T LR LGIP+RV+T
Sbjct: 236 NWSGTYTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVIT 295
Query: 321 TFASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILH 380
F SA T L +D YY+ G +G +W F E W R L Y GWQ+L
Sbjct: 296 NFNSAHDTDRNLSVDVYYDPMGNPLDKGS-DSVWNFHVWNEGWFVRSDLGPSYGGWQVLD 354
Query: 381 PSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDS- 439
+ + C V V+EG + L + +FA +NA + W + +S
Sbjct: 355 ATPQERSQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSV 414
Query: 440 NTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSL 499
N+ +G ISTK VGS+ D+T YKYPEGS QE++V ++ + L
Sbjct: 415 NSHTIGRYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGL 474
Query: 500 ETAS---PLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKL 556
ET + LK L + + + + L N S K V + + + YNG L ++
Sbjct: 475 ETEEQEPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAWTIIYNGTLVHEV 534
Query: 557 WRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAIC 616
W+ ++L E I + ++ +E+ + +R+TA+ + + + DI +
Sbjct: 535 WKDSATMSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDES-EVVVERDIILD 593
Query: 617 RPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPEN 676
P L +++ +A +P+ + N LD P+ DCV+ + G GL+ ++ P+
Sbjct: 594 NPTLTLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNLKIDVPTLGPKE 653
Query: 677 TMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 714
+F P+ G ++L + CN F + S+ V
Sbjct: 654 GSRVRFDILPSRSGTKQLLADFSCNKFPAIKAMLSIDV 691
>gi|39777599 transglutaminase 2 isoform b [Homo sapiens]
Length = 548
Score = 324 bits (831), Expect = 2e-88
Identities = 201/549 (36%), Positives = 286/549 (52%), Gaps = 27/549 (4%)
Query: 33 DALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALT 92
+ L ++ CD + N +HHT L +L VRRGQPF + L+F R + ++ + +
Sbjct: 3 EELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEG--RNYEASVDSLTFS 60
Query: 93 AQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQ 152
TG PS+ T+A FP+ + W+A V ++ + ++ +TTPA+A IG Y L L+
Sbjct: 61 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 120
Query: 153 VSGRKQ---LLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESW 209
S Q +LG F LLFN W DAV+L +E +R EY+L Q G IY G+A I+ W
Sbjct: 121 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 180
Query: 210 DFGQFEGDVIDLSLRLLSKD--------KQVEKWSQPVHVARVLGALLHFLKEQRVLPTP 261
+FGQFE ++D+ L LL + + + S PV+V RV+ +++ +Q VL
Sbjct: 181 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 240
Query: 262 QTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTT 321
+G GSV ILR+W + V GQ WV AAVACTVLRCLGIP RVVT
Sbjct: 241 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 300
Query: 322 FASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHP 381
+ SA LLI+ + NE G G+ IW F E WMTRP L GY+GWQ L P
Sbjct: 301 YNSAHDQNSNLLIEYFRNEFGEIQGDKSE-MIWNFHCWVESWMTRPDLQPGYEGWQALDP 359
Query: 382 SAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNT 441
+ C VPVRA+KEG L +FA +NA V W +DG++ + + +
Sbjct: 360 TPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRS 419
Query: 442 KYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLET 501
VG ISTK VG D EDIT YKYPEGS +E+E R EK+
Sbjct: 420 LIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEE--------- 470
Query: 502 ASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRKKL 561
+ + + ++ S+ + D + + N++ +E +L + + V YNG+L + K L
Sbjct: 471 -TGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYL 529
Query: 562 HLTLSANLE 570
L+ NLE
Sbjct: 530 ---LNLNLE 535
>gi|148664232 transglutaminase 6 [Homo sapiens]
Length = 706
Score = 324 bits (831), Expect = 2e-88
Identities = 214/711 (30%), Positives = 352/711 (49%), Gaps = 37/711 (5%)
Query: 32 MDALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVAL 91
M + + D+Q +RN HHT+ L VRRGQ F++ L + L + +
Sbjct: 1 MAGIRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTL----ELSRALDCEEILIF 56
Query: 92 TAQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLL 151
T +TG + S+ T+A F S L + W+A E + ++ T+S+ +P AVIG Y L +
Sbjct: 57 TMETGPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSI 116
Query: 152 QVSGRKQ---LLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAES 208
++S ++ LG+F LLFNPW ED VFL +E +R EY+L+ +G+I+ G I+A+
Sbjct: 117 RLSSHRKHSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQG 176
Query: 209 WDFGQFEGDVIDLSLRLLSKDK--------QVEKWSQPVHVARVLGALLHFLKEQRVLPT 260
W++GQFE D++++ L +L + V P++V RV+ A+++ ++ V+
Sbjct: 177 WNYGQFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQG 236
Query: 261 PQTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVT 320
G RGSV IL++WL GR +PV GQ WV A V CTVLRCLGI RVV+
Sbjct: 237 QWQGKYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVS 296
Query: 321 TFASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILH 380
F SA T L +D+Y + G + +W F E W R L Y+GWQ+L
Sbjct: 297 NFNSAHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLD 356
Query: 381 PSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSN 440
+ + C V A++EG + L +FA +NA + W ED + E SN
Sbjct: 357 ATPQEESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSN 416
Query: 441 TKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMERE----------- 489
TK +G ISTK VGSD DIT YKYPEGS +E++V + E
Sbjct: 417 TKKIGRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIRRA 476
Query: 490 ------KDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGV 543
+D+ + P + + + + +L+ P L D ++++ L N + + + V++ +
Sbjct: 477 GGRCLWRDDLLEPATKPSIAGKFKVLEPPM---LGHDLRLALCLANLTSRAQRVRVNLSG 533
Query: 544 QAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSES 603
+ Y A++ + + L EK I I + +S ++ + E+ + L AM ++
Sbjct: 534 ATILYTRKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKG 593
Query: 604 NLSCFAQEDIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHR 663
++DI + + IK+ A +T V++ N L ++DC + + G GL+
Sbjct: 594 E-KLLVEKDITL-EDFITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQE 651
Query: 664 ERSYRFRSVWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 714
+ S ++ P+ +F TP+ G ++L V++ F ++ + V V
Sbjct: 652 QLSIDVPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHV 702
>gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens]
Length = 638
Score = 297 bits (760), Expect = 3e-80
Identities = 182/572 (31%), Positives = 285/572 (49%), Gaps = 32/572 (5%)
Query: 174 EDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQFEGDVIDLSLRLLSKDKQVE 233
EDAV+L +E QR EY++N G IY G+ + I+ W++GQFE +ID+ L+LL K +
Sbjct: 64 EDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQ 123
Query: 234 K--------WSQPVHVARVLGALLHFLKEQRVLPTPQTQATQEGALLNKRRGSVPILRQW 285
PV+V+RV+ A+++ + VL ++ +GA + GSV IL+QW
Sbjct: 124 TDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQW 183
Query: 286 LTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTGGRLLIDEYYNEEGLQN 345
+PV GQ WV AAV CTV+RCLGIP RV+T F S T G L+IDEYY+ G
Sbjct: 184 NATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRIL 243
Query: 346 GEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPNGGGVLGSCDLVPVRAVKEGT 405
G ++ IW F ECWM R LP Y GWQ+L + + C VRA+KEG
Sbjct: 244 GNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGE 303
Query: 406 LGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCEDITQNY 465
+ L +F+ +NA C+ W + G + +T VGN ISTK + SD +DIT+NY
Sbjct: 304 VDLNYDTPFVFSMVNADCMSW-LVQGGKEQKLHQDTSSVGNFISTKSIQSDERDDITENY 362
Query: 466 KYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSL---PLRGDAQ 522
KY EGSLQE++V + ++ R R L+ + P L +P SL LR
Sbjct: 363 KYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDV 422
Query: 523 ISVTL--------------------VNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRKKLH 562
+ V+L +N S Q K +++ + Q++ ++G + W+
Sbjct: 423 VQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAF 482
Query: 563 LTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHLAI 622
+TLS K + +S + + + +R++A+ S + I + P + I
Sbjct: 483 ITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITI 542
Query: 623 KMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENTMCAKF 682
+ A QPL+ V N L +EDCV+++ G GL +++ + P++
Sbjct: 543 NVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIIL 602
Query: 683 QFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 714
+ P G +++ + N F+++ Y++V V
Sbjct: 603 ETVPFKSGQRQIQANMRSNKFKDIKGYRNVYV 634
Score = 50.8 bits (120), Expect = 4e-06
Identities = 25/61 (40%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
Query: 35 LGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQ 94
L + D Q++RNN HHT+ ++ L VRRGQ F + LYFR R+F P L + +
Sbjct: 5 LEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRN--RSFQPGLDNIIFVVE 62
Query: 95 T 95
T
Sbjct: 63 T 63
>gi|4507475 transglutaminase 1 [Homo sapiens]
Length = 817
Score = 267 bits (682), Expect = 3e-71
Identities = 198/720 (27%), Positives = 320/720 (44%), Gaps = 40/720 (5%)
Query: 3 QGEPSQRSTGLAGLYAAPAASPVFIKGSGMDALG----------IKSCDFQAAR---NNE 49
+G S T G + + PV +GSG++A G + D ++R N
Sbjct: 69 RGRGSSSGTRRPGSRGSDSRRPVS-RGSGVNAAGDGTIREGMLVVNGVDLLSSRSDQNRR 127
Query: 50 EHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQTGEQPSKINRTQATF 109
EHHT L VRRGQPF ++L + ++ L G P T
Sbjct: 128 EHHTDEYEYDELIVRRGQPFHMLLLLSRTYESS----DRITLELLIGNNPEVGKGTHVII 183
Query: 110 PISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQV---SGRKQLLL---GQ 163
P+ G W A V + Q+ + V T +A+IG + ++ +G QL +
Sbjct: 184 PVGK-GGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDPRNE 242
Query: 164 FTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQFEGDVIDLSL 223
+LFNPW ED V++ +E R EY+LN++G IY GT I +W++GQF+ V+D L
Sbjct: 243 IYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACL 302
Query: 224 RLLSK-DKQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQATQEGALLNKRRGSVPIL 282
+L + PV+V+RV+ A+++ L + VL + G + GSV IL
Sbjct: 303 YILDRRGMPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVEIL 362
Query: 283 RQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTGGRLLIDEYYNEEG 342
+L G V GQ WV A V TVLRCLG+ R VT F SA T L +D Y++E
Sbjct: 363 LSYLR-TGYSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENM 421
Query: 343 LQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPNGGGVLGSCDLVPVRAVK 402
+W F +CWM RP LP G+DGWQ++ + + C V ++K
Sbjct: 422 KPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESIK 481
Query: 403 EGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCEDIT 462
G + + +FA +N+ V W+ +DG+ ++ K +G I TK + S+ EDIT
Sbjct: 482 NGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAISSNMREDIT 541
Query: 463 QNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRP---PSLETASPLYLLLKAPSSLPLRG 519
YK+PEGS E++ +E +G +P + +A + + ++A ++ +
Sbjct: 542 YLYKHPEGS--------DAERKAVETAAAHGSKPNVYANRGSAEDVAMQVEAQDAV-MGQ 592
Query: 520 DAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFF 579
D +SV L+NHS + V+L + + Y GV K + L+ +T+ + +
Sbjct: 593 DLMVSVMLINHSSSRRTVKLHLYLSVTFYTGVSGTIFKETKKEVELAPGASDRVTMPVAY 652
Query: 580 SNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLTASVS 639
+ + + + L ES Q + P L++ + A Q +
Sbjct: 653 KEYRPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIV 712
Query: 640 LQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENTMCAKFQFTPTHVGLQRLTVEVD 699
+N L + + V + G GL R + + T+ + F P G ++L +D
Sbjct: 713 FKNPLPVTLTNVVFRLEGSGL-QRPKILNVGDIGGNETVTLRQSFVPVRPGPRQLIASLD 771
>gi|156627577 transglutaminase 4 (prostate) [Homo sapiens]
Length = 684
Score = 266 bits (679), Expect = 7e-71
Identities = 203/703 (28%), Positives = 321/703 (45%), Gaps = 42/703 (5%)
Query: 32 MDA---LGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKK 88
MDA L + DF N HHT + RRGQ F + L P++++ +
Sbjct: 2 MDASKELQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSY----HQ 57
Query: 89 VALTAQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYS 148
+ L TG PS T + D W A ++ + T++VT+ +A++G Y
Sbjct: 58 LKLEFSTGPNPSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQ 117
Query: 149 LLLQVSGRKQLLLGQ---FTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQ 205
L V +L + LLFNPW +ED VF+ +E +R EY+LN G Y+G A I+
Sbjct: 118 L--NVKTGNHILKSEENILYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIK 175
Query: 206 AESWDFGQFEGDVIDLSLRLLSKD--KQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQT 263
+ W+FGQFE +V+D + LL++ K ++ PV V R + A++ F K Q VL T
Sbjct: 176 CKPWNFGQFEKNVLDCCISLLTESSLKPTDR-RDPVLVCRAMCAMMSFEKGQGVLIGNWT 234
Query: 264 QATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFA 323
+ G K GS PIL+Q+ + + V GQ WV A + TVLR LGIPAR VT F
Sbjct: 235 GDYEGGTAPYKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGFD 293
Query: 324 SAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSA 383
SA T L +D Y NE G + +W F T+ WM RP LP+GYDGWQ + +
Sbjct: 294 SAHDTERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATP 353
Query: 384 PNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVW---KCCEDGTLELTDSN 440
+ C P+ A+++G + + +F+ +N ++W L +
Sbjct: 354 QERSQGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISME 413
Query: 441 TKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERV------EKEKMEREKDNGI 494
T +G NISTK VG DR DIT YKYPEGS +E++V++ E+E K+N
Sbjct: 414 TTSIGKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAFLLLSSEREHRRPVKEN-- 471
Query: 495 RPPSLETASPLYLLLKAPSSLPLRGDA-QISVTLVNHSEQEKAVQLAIGVQAVHYNGVLA 553
+L + S L G++ +V L + + V + + Y G
Sbjct: 472 -----------FLHMSVQSDDVLLGNSVNFTVILKRKTAALQNVNILGSFELQLYTGKKM 520
Query: 554 AKLWRKKLHLTLSANLEKI-ITI-GLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQE 611
AKL + + ++ +T+ + N + +R +A ES ++
Sbjct: 521 AKLCDLNKTSQIQGQVSEVTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIMASEV 580
Query: 612 DIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRS 671
+ P +I++P Q L + +N+L P+ D S+ G+ + S +
Sbjct: 581 FTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTS-DHGT 639
Query: 672 VWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 714
V P T+ ++ + TP G ++ V++ + + K V +
Sbjct: 640 VQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIVLI 682
>gi|119395709 coagulation factor XIII A1 subunit precursor [Homo
sapiens]
Length = 732
Score = 236 bits (602), Expect = 6e-62
Identities = 172/643 (26%), Positives = 291/643 (45%), Gaps = 24/643 (3%)
Query: 47 NNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQTGEQPSKINRTQ 106
N +HHT + +L VRRGQ F + + F P + P + G P + T
Sbjct: 61 NKVDHHTDKYENNKLIVRRGQSFYVQIDFSRP---YDPRRDLFRVEYVIGRYPQENKGTY 117
Query: 107 ATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQVSGRKQLLLGQFT- 165
PI S W A + R+ +S +S+ + ++G + + + V +L
Sbjct: 118 IPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSRNP 177
Query: 166 -----LLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQFEGDVID 220
+LFNPW +DAV+L NE +R EY+LN G+I+ G + I+ SW +GQFE ++D
Sbjct: 178 ETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILD 237
Query: 221 LSLRLLSKDKQ-VEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQATQEGALLNKRRGSV 279
L ++ + + + P+ V+RV A+++ ++ VL G + GSV
Sbjct: 238 TCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSV 297
Query: 280 PILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTGGRLLIDEYYN 339
IL ++ + PV GQ WV A V T LRCLGIPAR+VT + SA L +D +
Sbjct: 298 DILLEYRSSEN-PVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLE 356
Query: 340 EEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPNGGGVLGSCDLVPVR 399
E+G N + + +W + E WMTRP LP G+ GWQ + + + C V+
Sbjct: 357 EDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQ 416
Query: 400 AVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCE 459
A+K G + +FA +N+ + +DGT + + + ++G I TK +G D
Sbjct: 417 AIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVENVDATHIGKLIVTKQIGGDGMM 476
Query: 460 DITQNYKYPEGSLQEKEVLERV----EKEKMEREKDNGIRPPSLETASPLYLLLKAPSSL 515
DIT YK+ EG +E+ LE K+ + E G+ +++ S + + + +++
Sbjct: 477 DITDTYKFQEGQEEERLALETALMYGAKKPLNTE---GV----MKSRSNVDMDFEVENAV 529
Query: 516 PLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITI 575
L D ++S+T N+S + + Y GV A+ ++ +TL K +
Sbjct: 530 -LGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAV 588
Query: 576 GLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLT 635
+ + E L A +E+ Q+ + P + IK+ +T
Sbjct: 589 LIQAGEYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMT 648
Query: 636 ASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENTM 678
+V N L + + + + G G + R FR + P +T+
Sbjct: 649 VTVEFTNPLKETLRNVWVHLDGPG-VTRPMKKMFREIRPNSTV 690
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 33.1 bits (74), Expect = 0.93
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 446 NNISTKGVGSDRCED-ITQNYKYPEGSLQEKEVLERVEKEKMEREKDNG 493
N + T +G+ C+D +T+ ++ EG+++ V E EK+ ER+ G
Sbjct: 1080 NELETASLGARTCDDDLTEQHEEAEGAIKPTAVAEDDEKDTSERDNSEG 1128
>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
Length = 600
Score = 32.3 bits (72), Expect = 1.6
Identities = 31/130 (23%), Positives = 61/130 (46%), Gaps = 9/130 (6%)
Query: 478 LERVEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAV 537
+ R++KEK+ EK + +L+ L ++L+ PS D+Q+SV+ ++ SE +
Sbjct: 395 VHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILE-PSYNHSGCDSQMSVSEMSCSESTSSC 453
Query: 538 QLAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAM 597
Q ++ + V ++ L+ + L + G F N N P NT+++LT +
Sbjct: 454 Q------SLEHGSV--PEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLL 505
Query: 598 ATHSESNLSC 607
+ + C
Sbjct: 506 NSMGQEMSKC 515
>gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
Length = 555
Score = 32.3 bits (72), Expect = 1.6
Identities = 31/130 (23%), Positives = 61/130 (46%), Gaps = 9/130 (6%)
Query: 478 LERVEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAV 537
+ R++KEK+ EK + +L+ L ++L+ PS D+Q+SV+ ++ SE +
Sbjct: 350 VHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILE-PSYNHSGCDSQMSVSEMSCSESTSSC 408
Query: 538 QLAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAM 597
Q ++ + V ++ L+ + L + G F N N P NT+++LT +
Sbjct: 409 Q------SLEHGSV--PEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLL 460
Query: 598 ATHSESNLSC 607
+ + C
Sbjct: 461 NSMGQEMSKC 470
>gi|30520346 A kinase (PRKA) anchor protein 14 isoform a [Homo
sapiens]
Length = 197
Score = 32.3 bits (72), Expect = 1.6
Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 5/52 (9%)
Query: 635 TASVSLQNSLDAPMEDCVISILG--RGLIHRERSYRFRSVWPENTMCAKFQF 684
T VS DAP+ V+S +G + L+HR RFR W +N AK+ F
Sbjct: 138 TMKVSKTKPPDAPI---VVSYVGDHQALVHRPGMVRFRENWQKNLTDAKYSF 186
>gi|118498354 component of oligomeric golgi complex 4 [Homo sapiens]
Length = 789
Score = 31.6 bits (70), Expect = 2.7
Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 438 DSNTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKE-VLERV--EKEKMEREKDNGI 494
DS K G ++GVG RC +I+ LQE E V ER+ E++ +ERE D +
Sbjct: 9 DSPPKLSGVQQPSEGVGGGRCSEISAELIRSLTELQELEAVYERLCGEEKVVERELDALL 68
Query: 495 RPPSLETASPLYLLLKAPSSLPLRGDAQ 522
+ + + L P+ + GDA+
Sbjct: 69 EQQNTIESKMVTLHRMGPNLQLIEGDAK 96
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 31.2 bits (69), Expect = 3.5
Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 8/73 (10%)
Query: 459 EDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSLP-- 516
E++ + K +EKE+LER+EK+K R +D + +L P + L+ P LP
Sbjct: 552 EELKKKLKEKAKERREKEMLERLEKQK--RYEDQELTGKNL----PAFRLVDTPEGLPNT 605
Query: 517 LRGDAQISVTLVN 529
L GD + V ++
Sbjct: 606 LFGDVAMVVEFLS 618
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 30.8 bits (68), Expect = 4.6
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 426 WKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEK 485
W + T+++ D + +S+KG+ S +T+ K E ++KE LE+ EKE+
Sbjct: 631 WSKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKE-LEKSEKEE 689
Query: 486 ME 487
E
Sbjct: 690 DE 691
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 30.4 bits (67), Expect = 6.0
Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 473 QEKEVLERVEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSE 532
QE+E LER+E+E+ ERE+ + LE + + ++ P + ++ L + S
Sbjct: 230 QERERLERLERERQERERQEQLEREQLEWERERRI---SSAAAPASVETPLNSVLGDSSA 286
Query: 533 QEKAVQLA 540
E +Q A
Sbjct: 287 SEPGLQAA 294
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 30.4 bits (67), Expect = 6.0
Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 473 QEKEVLERVEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSE 532
QE+E LER+E+E+ ERE+ + LE + + ++ P + ++ L + S
Sbjct: 230 QERERLERLERERQERERQEQLEREQLEWERERRI---SSAAAPASVETPLNSVLGDSSA 286
Query: 533 QEKAVQLA 540
E +Q A
Sbjct: 287 SEPGLQAA 294
>gi|56682938 A kinase (PRKA) anchor protein 14 isoform b [Homo
sapiens]
Length = 137
Score = 30.4 bits (67), Expect = 6.0
Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 5/42 (11%)
Query: 645 DAPMEDCVISILG--RGLIHRERSYRFRSVWPENTMCAKFQF 684
DAP+ V+S +G + L+HR RFR W +N AK+ F
Sbjct: 88 DAPI---VVSYVGDHQALVHRPGMVRFRENWQKNLTDAKYSF 126
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,165,834
Number of Sequences: 37866
Number of extensions: 1326882
Number of successful extensions: 3405
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 3319
Number of HSP's gapped (non-prelim): 43
length of query: 721
length of database: 18,247,518
effective HSP length: 110
effective length of query: 611
effective length of database: 14,082,258
effective search space: 8604259638
effective search space used: 8604259638
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.