Search of human proteins with 165905601

Search of human proteins with 165905601

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|165905601 proline-serine-threonine phosphatase interacting
protein 2 [Homo sapiens]
         (334 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|165905601 proline-serine-threonine phosphatase interacting pr...   674   0.0  
gi|20149528 proline-serine-threonine phosphatase interacting pro...   292   3e-79
gi|226371723 FCH domain only 2 isoform a [Homo sapiens]                92   8e-19
gi|239049457 FCH domain only 1 isoform b [Homo sapiens]                90   2e-18
gi|29789054 FCH domain only 1 isoform b [Homo sapiens]                 90   2e-18
gi|239049440 FCH domain only 1 isoform a [Homo sapiens]                90   2e-18
gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]         83   4e-16
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]          83   4e-16
gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens]          83   4e-16
gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]          83   4e-16
gi|226371725 FCH domain only 2 isoform b [Homo sapiens]                81   1e-15
gi|148747351 protein kinase C and casein kinase substrate in neu...    69   6e-12
gi|24308229 protein kinase C and casein kinase substrate in neur...    65   1e-10
gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo sap...    62   7e-10
gi|19224660 protein kinase C and casein kinase substrate in neur...    62   7e-10
gi|239049540 FCH domain only 1 isoform c [Homo sapiens]                61   1e-09
gi|38524622 formin binding protein 1 [Homo sapiens]                    58   1e-08
gi|122937396 coiled-coil domain containing 150 [Homo sapiens]          50   2e-06
gi|71061468 centromere protein E [Homo sapiens]                        49   8e-06
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    46   5e-05
gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens]     45   7e-05
gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens]     45   7e-05
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    44   2e-04
gi|22027646 angiomotin like 1 [Homo sapiens]                           44   3e-04
gi|11342676 thyroid hormone receptor interactor 10 [Homo sapiens]      44   3e-04
gi|219803769 trichoplein [Homo sapiens]                                42   6e-04
gi|14150056 trichoplein [Homo sapiens]                                 42   6e-04
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     42   8e-04
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    42   8e-04
gi|157785548 PAS domain containing 1 [Homo sapiens]                    42   8e-04

>gi|165905601 proline-serine-threonine phosphatase interacting
           protein 2 [Homo sapiens]
          Length = 334

 Score =  674 bits (1739), Expect = 0.0
 Identities = 334/334 (100%), Positives = 334/334 (100%)

Query: 1   MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLS 60
           MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLS
Sbjct: 1   MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLS 60

Query: 61  RKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTE 120
           RKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTE
Sbjct: 61  RKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTE 120

Query: 121 LIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATS 180
           LIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATS
Sbjct: 121 LIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATS 180

Query: 181 KTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQ 240
           KTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQ
Sbjct: 181 KTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQ 240

Query: 241 QCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKNAVPAGKA 300
           QCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKNAVPAGKA
Sbjct: 241 QCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKNAVPAGKA 300

Query: 301 TGPNLARRGPLPIPKSSPDDPNYSLVDDYSLLYQ 334
           TGPNLARRGPLPIPKSSPDDPNYSLVDDYSLLYQ
Sbjct: 301 TGPNLARRGPLPIPKSSPDDPNYSLVDDYSLLYQ 334


>gi|20149528 proline-serine-threonine phosphatase interacting
           protein 1 [Homo sapiens]
          Length = 416

 Score =  292 bits (747), Expect = 3e-79
 Identities = 143/304 (47%), Positives = 199/304 (65%), Gaps = 1/304 (0%)

Query: 1   MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLS 60
           M +  FK  FW  D  +  GY+ ++Q L +GRK CK+ E+ L++RA  EERYGK+L+ ++
Sbjct: 2   MPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIA 61

Query: 61  RKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTE 120
           RK   GQ+EIN+L+ + +  KQQ++NV   HIQLA +LREE R +EEFRE+QK QRKK E
Sbjct: 62  RKAG-GQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE 120

Query: 121 LIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATS 180
            +MD + K K   +KK M++KK YEQKCRD D+AEQA  R +   + KQ EK   K    
Sbjct: 121 AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQC 180

Query: 181 KTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQ 240
           K +  ++++ Y   I  L+KVR EW+ EH   CEAF+ QE +R+   RNALW+H NQLS 
Sbjct: 181 KDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSM 240

Query: 241 QCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKNAVPAGKA 300
           QCV  DE+YE+VR +LE CSI  DI+ F+  + TG  PPAP+ Y+N+Y  +   + +   
Sbjct: 241 QCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPG 300

Query: 301 TGPN 304
             P+
Sbjct: 301 IQPS 304


>gi|226371723 FCH domain only 2 isoform a [Homo sapiens]
          Length = 810

 Score = 91.7 bits (226), Expect = 8e-19
 Identities = 64/288 (22%), Positives = 138/288 (47%), Gaps = 20/288 (6%)

Query: 1   MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLS 60
           M  + F  NFW        G+D +  ++ +G+ + KE  DF++ERA IEE Y + +  L+
Sbjct: 1   MVMAYFVENFWGE---KNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57

Query: 61  RKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKT- 119
            K     S++ T     +VFK   + +A CH+ L + L+E  ++++++ E+Q    KKT 
Sbjct: 58  -KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTK 116

Query: 120 ELIMDAIHKQKSLQ--FKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKL 177
           E +   +   +++Q   +    +K+NY  KC +++  ++  +        ++ EK  VK 
Sbjct: 117 EEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGA------TQREIEKAAVK- 169

Query: 178 ATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQ 237
             SK A +     Y L++      + +++ +  +  + F+  E   +   +  +    N 
Sbjct: 170 --SKKATD----TYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNA 223

Query: 238 LSQQCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYE 285
           + +  +   +++E+   ++   +++  I+ F   + TG+  P  I +E
Sbjct: 224 IKEIHLQIGQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFE 271


>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
          Length = 889

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 70/324 (21%), Positives = 146/324 (45%), Gaps = 25/324 (7%)

Query: 4   SLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKK 63
           S F  +FW        G++ +   +  G  + KE  DF++ERA IEE Y K +  LS+  
Sbjct: 2   SYFGEHFWGE---KNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLA 58

Query: 64  PCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQ-KLQRKKTELI 122
             G + + T     EVF+   D +A CH++L + L++  + +  + E+Q K  +K  E +
Sbjct: 59  SNG-TPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEV 117

Query: 123 MDAIHKQKSLQFKKTM--DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATS 180
           +  +   + L     +   +++NY  +C D++   +         + K+ +K   K   +
Sbjct: 118 VSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRR------ESTSQKEMDKAETKTKKA 171

Query: 181 KTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQ 240
             ++  S + Y       +  R +++ + + +   F+A E   +   +  L  + + +  
Sbjct: 172 AESLRRSVEKY-------NSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVED 224

Query: 241 QCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENF-----YSSQKNAV 295
             V   +++E+ ++++E  S++  +  F   + TG+  P P+ +E +       + K   
Sbjct: 225 THVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLR 284

Query: 296 PAGKATGPNLARRGPLPIPKSSPD 319
            A     P L+RR   P P ++ D
Sbjct: 285 GAKAFRLPGLSRREREPEPPAAVD 308


>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
          Length = 889

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 70/324 (21%), Positives = 146/324 (45%), Gaps = 25/324 (7%)

Query: 4   SLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKK 63
           S F  +FW        G++ +   +  G  + KE  DF++ERA IEE Y K +  LS+  
Sbjct: 2   SYFGEHFWGE---KNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLA 58

Query: 64  PCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQ-KLQRKKTELI 122
             G + + T     EVF+   D +A CH++L + L++  + +  + E+Q K  +K  E +
Sbjct: 59  SNG-TPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEV 117

Query: 123 MDAIHKQKSLQFKKTM--DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATS 180
           +  +   + L     +   +++NY  +C D++   +         + K+ +K   K   +
Sbjct: 118 VSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRR------ESTSQKEMDKAETKTKKA 171

Query: 181 KTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQ 240
             ++  S + Y       +  R +++ + + +   F+A E   +   +  L  + + +  
Sbjct: 172 AESLRRSVEKY-------NSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVED 224

Query: 241 QCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENF-----YSSQKNAV 295
             V   +++E+ ++++E  S++  +  F   + TG+  P P+ +E +       + K   
Sbjct: 225 THVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLR 284

Query: 296 PAGKATGPNLARRGPLPIPKSSPD 319
            A     P L+RR   P P ++ D
Sbjct: 285 GAKAFRLPGLSRREREPEPPAAVD 308


>gi|239049440 FCH domain only 1 isoform a [Homo sapiens]
          Length = 891

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 70/324 (21%), Positives = 146/324 (45%), Gaps = 25/324 (7%)

Query: 4   SLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKK 63
           S F  +FW        G++ +   +  G  + KE  DF++ERA IEE Y K +  LS+  
Sbjct: 2   SYFGEHFWGE---KNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLA 58

Query: 64  PCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQ-KLQRKKTELI 122
             G + + T     EVF+   D +A CH++L + L++  + +  + E+Q K  +K  E +
Sbjct: 59  SNG-TPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEV 117

Query: 123 MDAIHKQKSLQFKKTM--DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATS 180
           +  +   + L     +   +++NY  +C D++   +         + K+ +K   K   +
Sbjct: 118 VSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRR------ESTSQKEMDKAETKTKKA 171

Query: 181 KTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQ 240
             ++  S + Y       +  R +++ + + +   F+A E   +   +  L  + + +  
Sbjct: 172 AESLRRSVEKY-------NSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVED 224

Query: 241 QCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENF-----YSSQKNAV 295
             V   +++E+ ++++E  S++  +  F   + TG+  P P+ +E +       + K   
Sbjct: 225 THVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLR 284

Query: 296 PAGKATGPNLARRGPLPIPKSSPD 319
            A     P L+RR   P P ++ D
Sbjct: 285 GAKAFRLPGLSRREREPEPPAAVD 308


>gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]
          Length = 412

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 65/261 (24%), Positives = 116/261 (44%), Gaps = 9/261 (3%)

Query: 20  GYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEV 79
           G++ ++Q    G++  KE  +F++ER  IEE Y K+L  LS+     Q E  +L  A   
Sbjct: 155 GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEE-GSLGEAWAQ 213

Query: 80  FKQQVDNVAQCHIQLAQSLREEARK-MEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTM 138
            K+ + + A+ H++ +  L  E  K +  FRE  K   KK +  +  + KQ + ++    
Sbjct: 214 VKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVE 273

Query: 139 DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTL 198
            A+K   ++ RD +   Q +     L N  +++   +K A  K+     D   M  +   
Sbjct: 274 KARKALTERQRDLEMKTQQL--EIKLSNKTEED---IKKARRKSTQAGDD--LMRCVDLY 326

Query: 199 DKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLEM 258
           ++ + +W  E +      E  E ER+   R  L  +     +  + +    E V + L  
Sbjct: 327 NQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRK 386

Query: 259 CSIQRDIEYFVNQRKTGQIPP 279
               +D E +V + KTG I P
Sbjct: 387 VDPAKDRELWVREHKTGNIRP 407


>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
          Length = 476

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 65/261 (24%), Positives = 116/261 (44%), Gaps = 9/261 (3%)

Query: 20  GYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEV 79
           G++ ++Q    G++  KE  +F++ER  IEE Y K+L  LS+     Q E  +L  A   
Sbjct: 219 GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEE-GSLGEAWAQ 277

Query: 80  FKQQVDNVAQCHIQLAQSLREEARK-MEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTM 138
            K+ + + A+ H++ +  L  E  K +  FRE  K   KK +  +  + KQ + ++    
Sbjct: 278 VKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVE 337

Query: 139 DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTL 198
            A+K   ++ RD +   Q +     L N  +++   +K A  K+     D   M  +   
Sbjct: 338 KARKALTERQRDLEMKTQQL--EIKLSNKTEED---IKKARRKSTQAGDD--LMRCVDLY 390

Query: 199 DKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLEM 258
           ++ + +W  E +      E  E ER+   R  L  +     +  + +    E V + L  
Sbjct: 391 NQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRK 450

Query: 259 CSIQRDIEYFVNQRKTGQIPP 279
               +D E +V + KTG I P
Sbjct: 451 VDPAKDRELWVREHKTGNIRP 471


>gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens]
          Length = 416

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 65/261 (24%), Positives = 116/261 (44%), Gaps = 9/261 (3%)

Query: 20  GYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEV 79
           G++ ++Q    G++  KE  +F++ER  IEE Y K+L  LS+     Q E  +L  A   
Sbjct: 159 GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEE-GSLGEAWAQ 217

Query: 80  FKQQVDNVAQCHIQLAQSLREEARK-MEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTM 138
            K+ + + A+ H++ +  L  E  K +  FRE  K   KK +  +  + KQ + ++    
Sbjct: 218 VKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVE 277

Query: 139 DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTL 198
            A+K   ++ RD +   Q +     L N  +++   +K A  K+     D   M  +   
Sbjct: 278 KARKALTERQRDLEMKTQQL--EIKLSNKTEED---IKKARRKSTQAGDD--LMRCVDLY 330

Query: 199 DKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLEM 258
           ++ + +W  E +      E  E ER+   R  L  +     +  + +    E V + L  
Sbjct: 331 NQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRK 390

Query: 259 CSIQRDIEYFVNQRKTGQIPP 279
               +D E +V + KTG I P
Sbjct: 391 VDPAKDRELWVREHKTGNIRP 411


>gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]
          Length = 336

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 65/261 (24%), Positives = 116/261 (44%), Gaps = 9/261 (3%)

Query: 20  GYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEV 79
           G++ ++Q    G++  KE  +F++ER  IEE Y K+L  LS+     Q E  +L  A   
Sbjct: 79  GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEE-GSLGEAWAQ 137

Query: 80  FKQQVDNVAQCHIQLAQSLREEARK-MEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTM 138
            K+ + + A+ H++ +  L  E  K +  FRE  K   KK +  +  + KQ + ++    
Sbjct: 138 VKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVE 197

Query: 139 DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTL 198
            A+K   ++ RD +   Q +     L N  +++   +K A  K+     D   M  +   
Sbjct: 198 KARKALTERQRDLEMKTQQL--EIKLSNKTEED---IKKARRKSTQAGDD--LMRCVDLY 250

Query: 199 DKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLEM 258
           ++ + +W  E +      E  E ER+   R  L  +     +  + +    E V + L  
Sbjct: 251 NQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRK 310

Query: 259 CSIQRDIEYFVNQRKTGQIPP 279
               +D E +V + KTG I P
Sbjct: 311 VDPAKDRELWVREHKTGNIRP 331


>gi|226371725 FCH domain only 2 isoform b [Homo sapiens]
          Length = 777

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 55/196 (28%), Positives = 99/196 (50%), Gaps = 15/196 (7%)

Query: 1   MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLS 60
           M  + F  NFW        G+D +  ++ +G+ + KE  DF++ERA IEE Y + +  L+
Sbjct: 1   MVMAYFVENFWGE---KNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57

Query: 61  RKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKT- 119
            K     S++ T     +VFK   + +A CH+ L + L+E  ++++++ E+Q    KKT 
Sbjct: 58  -KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTK 116

Query: 120 ELIMDAIHKQKSLQ--FKKTMDAKKNYEQKCRDKD--EAEQAVSRSANLVNPKQQE---- 171
           E +   +   +++Q   +    +K+NY  KC +++  + E A  R       K ++    
Sbjct: 117 EEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDT 176

Query: 172 -KLFV-KLATSKTAVE 185
            KL+V K A +K   E
Sbjct: 177 YKLYVEKYALAKADFE 192


>gi|148747351 protein kinase C and casein kinase substrate in
           neurons 2 [Homo sapiens]
          Length = 486

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 67/280 (23%), Positives = 124/280 (44%), Gaps = 30/280 (10%)

Query: 12  SADILSTIG-YDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSR-------KK 63
           S+D    +G Y   ++ +++G + C +  + L ERA IE+ Y + L   +R       K 
Sbjct: 14  SSDSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKG 73

Query: 64  PCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSL-REEARKM-----EEFREKQKLQRK 117
           P    +  T+++A   F  + + V++ H+++  SL  ++  K+     E F ++     K
Sbjct: 74  P----QYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFK 129

Query: 118 KTELIMDAIHKQKSLQFKKTMD---AKKNYEQKCRDKDEAEQAVSRSAN-----LVNPKQ 169
           +T+   D   K +    KK  +   AKK +   C+   E + A+SR AN      +NP+Q
Sbjct: 130 ETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACK---EEKLAISREANSKADPSLNPEQ 186

Query: 170 QEKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRN 229
            +KL  K+   K  V  + + Y   +  LD+   ++     +  E  +  E +R+ FFR 
Sbjct: 187 LKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFRE 246

Query: 230 ALWLHVNQLSQQCVTS-DEMYEQVRKSLEMCSIQRDIEYF 268
            L      L    V     +Y  + +S+       D+ +F
Sbjct: 247 VLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWF 286


>gi|24308229 protein kinase C and casein kinase substrate in neurons
           1 [Homo sapiens]
          Length = 444

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 59/277 (21%), Positives = 123/277 (44%), Gaps = 41/277 (14%)

Query: 9   NFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLN-------LSR 61
           +FW         Y   ++ +++G + C +  + ++ERA IE+ YG+ L +       L  
Sbjct: 18  SFWEVG-----NYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLIE 72

Query: 62  KKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQS-LREEARKMEEFREKQKLQR---- 116
           K P    +  +L+RA      + D V++ H ++  + L E+  K++ +++    ++    
Sbjct: 73  KGP----QYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQIMGG 128

Query: 117 -KKTELIMDAIHKQKSLQFKKTMD---AKKNYEQKCRDKDEA--EQAVSRSANLVNPKQQ 170
            K+T+   D   K +    KK  +   AKK Y   C+++  A   +  S++   V P+QQ
Sbjct: 129 FKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTEQSVTPEQQ 188

Query: 171 EKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEW---QSEHIKACEAFEAQEC------ 221
           +KL  K+   K  V+ + + Y   +  + K   ++     +  + C+ FE +        
Sbjct: 189 KKLQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKEV 248

Query: 222 -----ERINFFRNALWLHVNQLSQQCVTSDEMYEQVR 253
                  +N   N+ ++HV +  +Q +   +  E +R
Sbjct: 249 LLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLR 285


>gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo
           sapiens]
          Length = 506

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 56/251 (22%), Positives = 106/251 (42%), Gaps = 7/251 (2%)

Query: 21  YDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRK--KPCGQSEINTLKRALE 78
           Y N+ +   NG   CK+    L++RA +E  Y K L  L+ K  K    +  + +  A  
Sbjct: 14  YKNLKEFSQNGENFCKQVTSVLQQRANLEISYAKGLQKLASKLSKALQNTRKSCVSSAWA 73

Query: 79  VFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSL---QFK 135
              + + + A  H +L +++  EA  ++   +   +Q KK + + + + K  +L    + 
Sbjct: 74  WASEGMKSTADLHQKLGKAIELEA--IKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWN 131

Query: 136 KTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHI 195
           + + AKK      +  +   Q V  S   +  K++ KL  KL  S   +E  D+ Y    
Sbjct: 132 QQIKAKKKLMVSTKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKN 191

Query: 196 GTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRKS 255
                 R +W++      ++    E ERI    N L  +   +S    T    + Q+  +
Sbjct: 192 MAGYSTRLKWENTLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCA 251

Query: 256 LEMCSIQRDIE 266
           +    I++DI+
Sbjct: 252 ISKIDIEKDIQ 262


>gi|19224660 protein kinase C and casein kinase substrate in neurons
           3 [Homo sapiens]
          Length = 424

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 67/347 (19%), Positives = 141/347 (40%), Gaps = 30/347 (8%)

Query: 8   GNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRK---KP 64
           G+FW A       Y   +Q + +G + C +     +ERA IE+ Y + L + +RK     
Sbjct: 14  GSFWEAG-----NYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGTV 68

Query: 65  CGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQR------KK 118
               +  TL++A   F    + ++  H+++ + L+ +  +     ++    R      ++
Sbjct: 69  EKGPQYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAFHRPVLGGFRE 128

Query: 119 TELIMDAIHKQKSLQFKKTMD---AKKNYEQKCRDKDEAE--QAVSRSANLVNPKQQEKL 173
           +    D   K +    K+  +   +KK+Y    +D+  A+  ++ +++ + V+ +Q  KL
Sbjct: 129 SRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAVSQEQLRKL 188

Query: 174 FVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRN-ALW 232
             ++       E +   Y   +  L +    +  +  +A E  +A E +R+ FF++  L 
Sbjct: 189 QERVERCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAAERQRLLFFKDMLLT 248

Query: 233 LHVNQLSQQCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQK 292
           LH +          E++  + + +E  S + D+ ++ +    G     P   E    +Q+
Sbjct: 249 LHQHLDLSSSEKFHELHRDLHQGIEAASDEEDLRWWRSTHGPGMAMNWPQFEEWSLDTQR 308

Query: 293 NAVPAGKA---------TGPNLARRGPLPIPKSSPDDPNYSLVDDYS 330
                 K          T     R G  P P  SP  P     +++S
Sbjct: 309 TISRKEKGGRSPDEVTLTSIVPTRDGTAP-PPQSPGSPGTGQDEEWS 354


>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
          Length = 839

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 48/250 (19%), Positives = 113/250 (45%), Gaps = 21/250 (8%)

Query: 78  EVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQ-KLQRKKTELIMDAIHKQKSLQFKK 136
           EVF+   D +A CH++L + L++  + +  + E+Q K  +K  E ++  +   + L    
Sbjct: 22  EVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVSTLDAVQVLSGVS 81

Query: 137 TM--DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLH 194
            +   +++NY  +C D++   +  +      + K+ +K   K   +  ++  S + Y   
Sbjct: 82  QLLPKSRENYLNRCMDQERLRREST------SQKEMDKAETKTKKAAESLRRSVEKY--- 132

Query: 195 IGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRK 254
               +  R +++ + + +   F+A E   +   +  L  + + +    V   +++E+ ++
Sbjct: 133 ----NSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQ 188

Query: 255 SLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENF-----YSSQKNAVPAGKATGPNLARRG 309
           ++E  S++  +  F   + TG+  P P+ +E +       + K    A     P L+RR 
Sbjct: 189 NIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRE 248

Query: 310 PLPIPKSSPD 319
             P P ++ D
Sbjct: 249 REPEPPAAVD 258


>gi|38524622 formin binding protein 1 [Homo sapiens]
          Length = 617

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 59/286 (20%), Positives = 123/286 (43%), Gaps = 12/286 (4%)

Query: 21  YDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRK---KPCGQSEINTLKRAL 77
           +DN+ +H   G    +++  F+KER  IE  Y K L NLS+K   K   + E      + 
Sbjct: 11  FDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEYKYTSC 70

Query: 78  EVF---KQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQ- 133
           + F     ++++ A  H  +++++  +   ++  R  Q+L++++     D    Q+ ++ 
Sbjct: 71  KAFISNLNEMNDYAGQHEVISENMASQI-IVDLARYVQELKQERKSNFHDGRKAQQHIET 129

Query: 134 -FKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQ--EKLFVKLATSKTAVEDSDKA 190
            +K+   +K+ +E+ C++ D A+Q   +    +N  +   EK   +        EDS   
Sbjct: 130 CWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRHQMAEDSKAD 189

Query: 191 YMLHIGTLDKVREEWQSEHI-KACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMY 249
           Y   +   +  + E+   HI    +  +  E  RI     ++  +     Q      +  
Sbjct: 190 YSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCL 249

Query: 250 EQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKNAV 295
           + + K+ E    + D +  +   K+G  PP  I +E++    K  V
Sbjct: 250 DGIVKAAESIDQKNDSQLVIEAYKSGFEPPGDIEFEDYTQPMKRTV 295


>gi|122937396 coiled-coil domain containing 150 [Homo sapiens]
          Length = 1101

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 61/249 (24%), Positives = 103/249 (41%), Gaps = 45/249 (18%)

Query: 32   RKNCKEFEDFLKERAAIEERYGKDLLNLSRK---------KPCGQSEINTLKRALEVFKQ 82
            R+N + F+D + E + +E     + +   RK         K   Q E+  LK+AL+    
Sbjct: 803  RQNLETFKDRMTEESKVEAELHAERIEALRKQFQTERETTKKVAQREVAELKKALDEANF 862

Query: 83   QVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDA-------------IHKQ 129
            +   V++ + +L Q L E  + +E  +EK K Q+ + +L + A             I K+
Sbjct: 863  RSVEVSRTNRELRQKLAELEKILESNKEKIKNQKTQIKLHLSAKANNAQNIERMKQIEKE 922

Query: 130  -KSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSD 188
             K ++  K    KKNYEQ        ++ V    NL      +K    LA S+      +
Sbjct: 923  LKQMELIKDQYQKKNYEQSL----SIQRFVCEMTNL------QKEMQMLAKSQYDASVRN 972

Query: 189  KAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEM 248
            K   LH+    K+R+E ++     C+  E    E +   +       N L +  V S   
Sbjct: 973  KQQELHLEAERKIRQELENR----CQELE----ETVRHLKKCKEATENTLKEASVES--- 1021

Query: 249  YEQVRKSLE 257
             EQ+  +LE
Sbjct: 1022 -EQITANLE 1029



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 36/163 (22%), Positives = 71/163 (43%), Gaps = 26/163 (15%)

Query: 41  FLKERA-AIEERYGKDL-------LNL-------SRKKPCGQSEINTLKRALEVFKQQVD 85
           FLK+R  AI+E + KDL       +NL         ++   Q E+  L   L++  Q   
Sbjct: 134 FLKDRLNAIQEEHSKDLKLLHLEVMNLRQQLRAVKEEEDKAQDEVQRLTATLKIASQTKK 193

Query: 86  NVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTMDAKKNYE 145
           N A    +L  + R+   K++E R     Q  + + + +++ K  S    K  +     E
Sbjct: 194 NAAIIEEELKTTKRKMNLKIQELRR----QLAQEKYLRESLEKSASAMLLKIQEMGSTVE 249

Query: 146 QKCRDKDEAEQ-------AVSRSANLVNPKQQEKLFVKLATSK 181
            + +     +Q       ++  +  L+  +Q++K  +++ATS+
Sbjct: 250 VERKQVHILQQNCIALRDSIQSAQELLAQEQKKKEELEIATSQ 292


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 45/191 (23%), Positives = 89/191 (46%), Gaps = 11/191 (5%)

Query: 21  YDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRAL--- 77
           YDN++      R   +E E  LKE+  ++E    +      ++     EI+ LK  +   
Sbjct: 507 YDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHA 566

Query: 78  EVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQFKKT 137
           EV+ Q ++N     ++L +   ++ +K++E+ + QKL+  K    MD  +  +S++  K 
Sbjct: 567 EVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIK----MDLSYSLESIEDPKQ 622

Query: 138 MDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGT 197
           M       +      + E A  RS NL   + +EK+  +LAT+   +E+  + Y   +  
Sbjct: 623 MKQTLFDAETVALDAKRESAFLRSENL---ELKEKM-KELATTYKQMENDIQLYQSQLEA 678

Query: 198 LDKVREEWQSE 208
             K++ + + E
Sbjct: 679 KKKMQVDLEKE 689



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 53/266 (19%), Positives = 115/266 (43%), Gaps = 46/266 (17%)

Query: 21   YDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVF 80
            Y +  Q   N +    +FE   K      ER  ++++NLS++     S +  LK  L   
Sbjct: 812  YKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYK 871

Query: 81   KQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTMDA 140
             Q++        +  + ++E   +ME+ +E    Q +  +  +  + ++K+L  +K    
Sbjct: 872  TQELQ-------EKTREVQERLNEMEQLKE----QLENRDSTLQTVEREKTLITEKLQQT 920

Query: 141  KKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLDK 200
             +  +   ++KD+ +Q             QE L ++    K+ + D+     ++I T ++
Sbjct: 921  LEEVKTLTQEKDDLKQL------------QESLQIERDQLKSDIHDT---VNMNIDTQEQ 965

Query: 201  VREEWQS--EHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQV-----R 253
            +R   +S  +H +     +++  E ++  RN   LH+ + + +  T DE  +++     +
Sbjct: 966  LRNALESLKQHQETINTLKSKISEEVS--RN---LHMEENTGE--TKDEFQQKMVGIDKK 1018

Query: 254  KSLEMCSIQ------RDIEYFVNQRK 273
            + LE  + Q      +D E    QRK
Sbjct: 1019 QDLEAKNTQTLTADVKDNEIIEQQRK 1044



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 37/155 (23%), Positives = 75/155 (48%), Gaps = 14/155 (9%)

Query: 37   EFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEIN---TLKRALEVFKQQVDNVAQCHIQ 93
            E E+ LKE++   +   + LLN+  +    Q +IN    LK  L+  +  ++++    ++
Sbjct: 1124 EVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLE 1183

Query: 94   LAQSLREEARKMEEFREKQKLQR---KKTELIMDAIH------KQKSLQFKKTMD-AKKN 143
            LAQ L E   +++   +++K+ +   K  E   D +       +   LQ K+ +  A  +
Sbjct: 1184 LAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIH 1243

Query: 144  YEQKCRDKDEAEQAVS-RSANLVNPKQQEKLFVKL 177
             ++     DE  ++VS ++A ++N +  EK   KL
Sbjct: 1244 LKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKL 1278



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 44/261 (16%), Positives = 115/261 (44%), Gaps = 31/261 (11%)

Query: 28   LNNGRKNCKEFEDF---LKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQV 84
            +N  +K   E E     +K+++    +   + LNL++K      E+ ++ +  +  ++  
Sbjct: 1839 VNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVE 1898

Query: 85   DNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTMDAKKNY 144
            + +     QL +SL+E   +  E +++ K  R  ++   + + K +    +KT+      
Sbjct: 1899 ETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQ 1958

Query: 145  EQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREE 204
            +   + KDE ++ +         ++ +K  ++L   K  V  S K     I  +++++++
Sbjct: 1959 KDLDKSKDELQKKI---------QELQKKELQLLRVKEDVNMSHK----KINEMEQLKKQ 2005

Query: 205  WQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLEMCSIQRD 264
            ++++++       + +  R++ F+    LH +    + V  +   +++R+  E   ++RD
Sbjct: 2006 FEAQNL-------SMQSVRMDNFQLTKKLHESLEEIRIVAKER--DELRRIKESLKMERD 2056

Query: 265  ------IEYFVNQRKTGQIPP 279
                   E     R+  Q+ P
Sbjct: 2057 QFIATLREMIARDRQNHQVKP 2077



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 45/238 (18%), Positives = 100/238 (42%), Gaps = 34/238 (14%)

Query: 36   KEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLA 95
            K+F++  K + +  +     +L L+ +    Q EI  + +  E  K+  + +     QL 
Sbjct: 1551 KQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLK 1610

Query: 96   QSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAE 155
            ++ +E   KM+E +EK+                    QF K     +  E+ C  +   E
Sbjct: 1611 ENTKEIVAKMKESQEKE-------------------YQFLKMTAVNETQEKMCEIEHLKE 1651

Query: 156  QAVSRSANLVNPKQQ-----EKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHI 210
            Q  ++  NL N + +     + L   L   ++  ++ D   +  +    KV  +   E++
Sbjct: 1652 QFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDD--LRSVEETLKVERDQLKENL 1709

Query: 211  KACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQV-RKSLEMCSIQRDIEY 267
            +     + ++ E +        +H++ L +   T D++   V  K+ E+ ++Q+D+E+
Sbjct: 1710 RETITRDLEKQEELKI------VHMH-LKEHQETIDKLRGIVSEKTNEISNMQKDLEH 1760



 Score = 28.9 bits (63), Expect = 6.7
 Identities = 18/63 (28%), Positives = 31/63 (49%)

Query: 51   RYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFRE 110
            R   + L L+ K    Q EI +L +  +  K   + +   H QL + +RE   K++E + 
Sbjct: 1325 RIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQS 1384

Query: 111  KQK 113
            KQ+
Sbjct: 1385 KQE 1387


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 59/236 (25%), Positives = 93/236 (39%), Gaps = 59/236 (25%)

Query: 30   NGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQVDNVAQ 89
            N  K C+  ED L E     E   + L  L+ +K   Q+E   L R LE  +  V  +++
Sbjct: 1245 NLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSR 1304

Query: 90   CHIQLAQSLREEARKMEE---------------------FRE--------KQKLQRK--- 117
                  Q   E  R++EE                      RE        K +LQR    
Sbjct: 1305 SKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSK 1364

Query: 118  --------KTELIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAV-SRSANLVNPK 168
                    +T+   DAI + + L+     +AKK   Q+ +D +E  +AV ++ A+L   K
Sbjct: 1365 ANSEVAQWRTKYETDAIQRTEELE-----EAKKKLAQRLQDSEEQVEAVNAKCASLEKTK 1419

Query: 169  QQ-----EKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQ 219
            Q+     E L V +  + +     DK         DKV  EW+++    CE  +A+
Sbjct: 1420 QRLQGEVEDLMVDVERANSLAAALDKKQR----NFDKVLAEWKTK----CEESQAE 1467



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 34/147 (23%), Positives = 70/147 (47%), Gaps = 28/147 (19%)

Query: 68   SEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTEL-IMDAI 126
            +E+ +   A+ + K+   ++ +  IQL+ + R+ A  ++  R  Q  Q K T+L + DA+
Sbjct: 1604 AEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQG-QLKDTQLHLDDAL 1662

Query: 127  HKQKSLQ-----------------------FKKTMDAKKNYEQKCRDKDEAEQAV-SRSA 162
              Q+ L+                        ++T  A+K  EQ+  D +E  Q + +++ 
Sbjct: 1663 RGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNT 1722

Query: 163  NLVNPKQQEKLFVKLATSKTAVEDSDK 189
            +L++ K  +KL   L   ++ VED+ +
Sbjct: 1723 SLIHTK--KKLETDLMQLQSEVEDASR 1747



 Score = 32.0 bits (71), Expect = 0.79
 Identities = 60/259 (23%), Positives = 104/259 (40%), Gaps = 39/259 (15%)

Query: 44   ERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEAR 103
            ERA  EE    +L    RK     SE+      LE+   +V+          ++L EE  
Sbjct: 925  ERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELS 984

Query: 104  KMEE-----FREKQKLQRKKTELIMD---------AIHKQKSLQFKKTMDAKKNYEQKCR 149
             ++E      REK+ LQ    + + D         +++K KS   ++  D + + EQ+ +
Sbjct: 985  GLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKK 1044

Query: 150  DKDEAEQ-----------AVSRSANLVNPKQQ-----EKLFVKLATSKTAVEDSDKAYML 193
             + + E+           A     +L N KQQ     +K   +    ++ VED      L
Sbjct: 1045 LRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQ---TL 1101

Query: 194  HIGTLDKVRE-----EWQSEHIKACEAFEAQ-ECERINFFRNALWLHVNQLSQQCVTSDE 247
             +    K++E     E   E I+A  A  A+ E +R ++ R    L         VTS +
Sbjct: 1102 GLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQ 1161

Query: 248  MYEQVRKSLEMCSIQRDIE 266
            +    ++  E   ++RD+E
Sbjct: 1162 IELNKKREAEFLKLRRDLE 1180



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 48/259 (18%), Positives = 105/259 (40%), Gaps = 40/259 (15%)

Query: 32   RKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQVDNVAQCH 91
            ++  ++ +D L +  A  +   + L+ L ++K   Q ++      L   +++ D + +  
Sbjct: 854  KEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAK 913

Query: 92   IQLAQSLREEARKMEEFRE--------KQKLQRKKTELIMDA---------IHKQKSLQF 134
             QL   ++E   + E+  E        K+KL+ + +EL  D          + K+K    
Sbjct: 914  FQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK---- 969

Query: 135  KKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLH 194
              T +  KN  ++    DE    ++R    +    Q+ L            D  +A    
Sbjct: 970  HATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQAL------------DDLQAEEDK 1017

Query: 195  IGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVN-QLSQQCVTSDEMYEQ-- 251
            + +L+K + + + +      + E ++  R++  RN   L  + +L+Q+ +   E  +Q  
Sbjct: 1018 VNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQL 1077

Query: 252  ----VRKSLEMCSIQRDIE 266
                 +K  E C +Q  +E
Sbjct: 1078 DERLKKKDFEYCQLQSKVE 1096



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 25/172 (14%)

Query: 39   EDFLKERAAIEERYGK-----------DLLNLSRKKPCGQSEINTLKRALEVFKQQVDNV 87
            ++ LKE+ AI ER               L    R +   + E+      +++   Q  ++
Sbjct: 1665 QEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSL 1724

Query: 88   AQCHIQLAQSLREEARKMEEF-REKQKLQRKKTELIMDAIHKQKSLQFKKTMDA-----K 141
                 +L   L +   ++E+  R+ +  + K  + I DA    + L+ ++   A     K
Sbjct: 1725 IHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1784

Query: 142  KNYEQKCRD----KDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDK 189
            KN EQ  +D     DEAEQ   +       KQ +KL  ++   +  +E   K
Sbjct: 1785 KNLEQTVKDLQHRLDEAEQLALKGGK----KQIQKLETRIRELEFELEGEQK 1832


>gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens]
          Length = 551

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 53/292 (18%), Positives = 116/292 (39%), Gaps = 41/292 (14%)

Query: 21  YDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRK---KPCGQSE---INTLK 74
           +D++ +H   G    + +  F+KER  IE+ Y K L NL +K   K   + E     +  
Sbjct: 11  FDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEEPRFTSCV 70

Query: 75  RALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQF 134
               +  +  D   Q  +   +       ++  +    K +RK          +   + +
Sbjct: 71  AFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCW 130

Query: 135 KKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLH 194
           K+  ++KK +E++CR+ ++A+Q+  R  N  N             +K  VE + +   L 
Sbjct: 131 KQMDNSKKKFERECREAEKAQQSYERLDNDTN------------ATKADVEKAKQQLNLR 178

Query: 195 IGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQ-QCVTSDEMY---- 249
               D+ + E+ ++     + F  ++ +        ++  + ++ + + +   E Y    
Sbjct: 179 THMADENKNEYAAQ----LQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFA 234

Query: 250 EQVRKSLEMCS--------------IQRDIEYFVNQRKTGQIPPAPIMYENF 287
           +  RK + + S               +RD +  V+  K+G  PP    +E++
Sbjct: 235 DSERKVIPIISKCLEGMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDY 286


>gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens]
          Length = 547

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 53/292 (18%), Positives = 116/292 (39%), Gaps = 41/292 (14%)

Query: 21  YDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRK---KPCGQSE---INTLK 74
           +D++ +H   G    + +  F+KER  IE+ Y K L NL +K   K   + E     +  
Sbjct: 11  FDSLDKHTQWGIDFLERYAKFVKERIEIEQNYAKQLRNLVKKYCPKRSSKDEEPRFTSCV 70

Query: 75  RALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQF 134
               +  +  D   Q  +   +       ++  +    K +RK          +   + +
Sbjct: 71  AFFNILNELNDYAGQREVVAEEMAHRVYGELMRYAHDLKTERKMHLQEGRKAQQYLDMCW 130

Query: 135 KKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLH 194
           K+  ++KK +E++CR+ ++A+Q+  R  N  N             +K  VE + +   L 
Sbjct: 131 KQMDNSKKKFERECREAEKAQQSYERLDNDTN------------ATKADVEKAKQQLNLR 178

Query: 195 IGTLDKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQ-QCVTSDEMY---- 249
               D+ + E+ ++     + F  ++ +        ++  + ++ + + +   E Y    
Sbjct: 179 THMADENKNEYAAQ----LQNFNGEQHKHFYVVIPQIYKQLQEMDERRTIKLSECYRGFA 234

Query: 250 EQVRKSLEMCS--------------IQRDIEYFVNQRKTGQIPPAPIMYENF 287
           +  RK + + S               +RD +  V+  K+G  PP    +E++
Sbjct: 235 DSERKVIPIISKCLEGMILAAKSVDERRDSQMVVDSFKSGFEPPGDFPFEDY 286


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 55/251 (21%), Positives = 102/251 (40%), Gaps = 55/251 (21%)

Query: 18   TIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRAL 77
            T   + II+   N  K C+  ED + E  +  E   + + +L+ ++   Q+E   L R L
Sbjct: 1232 TSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQL 1291

Query: 78   EVFKQQVDNVAQCHIQLAQSLREEARKMEE---------------------FRE------ 110
            +  +  +  + +  +   Q L +  R++EE                      RE      
Sbjct: 1292 DEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEET 1351

Query: 111  --KQKLQRK-----------KTELIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQA 157
              K +LQR            +T+   DAI + + L+     +AKK   Q+ ++ +EA +A
Sbjct: 1352 EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE-----EAKKKLAQRLQEAEEAVEA 1406

Query: 158  V-SRSANLVNPKQQ-----EKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIK 211
            V ++ ++L   K +     E L V +  S  A    DK         DK+  EW+ ++ +
Sbjct: 1407 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR----NFDKILAEWKQKYEE 1462

Query: 212  ACEAFEAQECE 222
            +    E+ + E
Sbjct: 1463 SQSELESSQKE 1473



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 45/180 (25%), Positives = 84/180 (46%), Gaps = 27/180 (15%)

Query: 43   KERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEA 102
            KE+ A++E + + L +L  +    + ++NTL +A    +QQVD+       L  SL +E 
Sbjct: 994  KEKKALQEAHQQALDDLQAE----EDKVNTLTKAKVKLEQQVDD-------LEGSLEQEK 1042

Query: 103  R-KMEEFREKQKLQ---RKKTELIMDAIHKQKSLQFKKTMDAKKNYEQKCRD-KDEAEQA 157
            + +M+  R K+KL+   +   E IMD  + ++ L  +     KK++E    + + E EQA
Sbjct: 1043 KVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERL---KKKDFELNALNARIEDEQA 1099

Query: 158  VSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFE 217
            +          Q +K   +L      +E+  +A       ++K+R +   E  +  E  E
Sbjct: 1100 LG--------SQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLE 1151



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 13/119 (10%)

Query: 97  SLREEARKMEEFREKQKLQRKKTELIMDAIHKQKS---LQFKKTMDAKKNYEQKC----R 149
           S++EE  +++E  EK + +RK+ E  M ++ ++K+   LQ +   D   + E++C    +
Sbjct: 851 SMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIK 910

Query: 150 DKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIG----TLDKVREE 204
           +K + E  V      +  + +E++  +L   K  +ED        I     TL KV +E
Sbjct: 911 NKIQLEAKVKEMNERL--EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKE 967



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 26/144 (18%)

Query: 68   SEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIH 127
            +E  +   AL V K+   ++ +  IQL+ + R  A   ++ +  Q L +     + DA+ 
Sbjct: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVR 1662

Query: 128  KQKSLQFKKTMDAKKN-------------YEQKCRDKDEAEQAV-----------SRSAN 163
                L+    +  ++N              EQ  R +  AEQ +           S++ +
Sbjct: 1663 ANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTS 1722

Query: 164  LVNPKQQEKLFVKLATSKTAVEDS 187
            L+N  Q++K+   L+  +T VE++
Sbjct: 1723 LIN--QKKKMDADLSQLQTEVEEA 1744



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 39/171 (22%), Positives = 67/171 (39%), Gaps = 25/171 (14%)

Query: 40   DFLKERAAIEERYGKDLL-----------NLSRKKPCGQSEINTLKRALEVFKQQVDNVA 88
            D LKE  AI ER    L               R +   + E+      +++   Q  ++ 
Sbjct: 1665 DDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLI 1724

Query: 89   QCHIQLAQSLREEARKMEE-FREKQKLQRKKTELIMDAIHKQKSLQFKKTMDA-----KK 142
                ++   L +   ++EE  +E +  + K  + I DA    + L+ ++   A     KK
Sbjct: 1725 NQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1784

Query: 143  NYEQKCRD----KDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDK 189
            N EQ  +D     DEAEQ   +       KQ +KL  ++   +  +E   K
Sbjct: 1785 NMEQTIKDLQHRLDEAEQIALKGGK----KQLQKLEARVRELENELEAEQK 1831


>gi|22027646 angiomotin like 1 [Homo sapiens]
          Length = 956

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 52/211 (24%), Positives = 92/211 (43%), Gaps = 30/211 (14%)

Query: 77  LEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHK-----QKS 131
           L  F++++  +++ +    +SL +   K E      K  R K E  +  +H      +  
Sbjct: 469 LHKFEKELQRISEAY----ESLVKSTTKRESL---DKAMRNKLEGEIRRLHDFNRDLRDR 521

Query: 132 LQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAY 191
           L+      + + YE     +D+A +    S N    K++EKL ++LA  +TA ED    +
Sbjct: 522 LETANRQLSSREYEGH---EDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASED----H 574

Query: 192 MLHIGTLDKVREEWQSEHIKACEAFEAQEC--ERINFFRNALWLHVNQLSQQCVTSDEMY 249
             HI  LD+     Q+  IK  E    ++   E++   + AL     QL   C   ++M 
Sbjct: 575 RRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQAL----TQLQSACEKREQME 630

Query: 250 EQVRKSLEMCSIQRDIEYFVNQRKTGQIPPA 280
            ++R  LE     R+++    Q+K G   PA
Sbjct: 631 RRLRTWLE-----RELDALRTQQKHGNGQPA 656


>gi|11342676 thyroid hormone receptor interactor 10 [Homo sapiens]
          Length = 545

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 59/316 (18%), Positives = 125/316 (39%), Gaps = 39/316 (12%)

Query: 21  YDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRK-------KPCGQSEINTL 73
           ++ + +H   G      +  F+KER  +E+ Y K L +L +K       K   +S+ +  
Sbjct: 11  FEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQ 70

Query: 74  KRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQ 133
           +  +++ ++  D   Q  +           ++ ++ ++ K +RK          +Q    
Sbjct: 71  QSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENG 130

Query: 134 FKKTMDAKKNYEQKCRDKDEAEQAVSR--------SANLVNPKQQEKLFVKLATSKTAVE 185
           FK+  ++K+ +E+ CR+ ++A Q   R         A++   KQQ  L   +A      E
Sbjct: 131 FKQLENSKRKFERDCREAEKAAQTAERLDQDINATKADVEKAKQQAHLRSHMA------E 184

Query: 186 DSDKAYMLHIGTLDKVREEW----QSEHIKACEAFEAQECERINFFRNAL---WLHVNQL 238
           +S   Y   +   ++ +  +      +     +  + +   R+      L    L V  +
Sbjct: 185 ESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPI 244

Query: 239 SQQCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKNAVPAG 298
             +C+      E ++ +      + D    +   K+G   P  + +E+F S   N  P+ 
Sbjct: 245 IAKCL------EGMKVAANAVDPKNDSHVLIELHKSGFARPGDVEFEDF-SQPMNRAPSD 297

Query: 299 KATG-PNLAR---RGP 310
            + G P+  R   RGP
Sbjct: 298 SSLGTPSDGRPELRGP 313


>gi|219803769 trichoplein [Homo sapiens]
          Length = 498

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 43/206 (20%), Positives = 91/206 (44%), Gaps = 19/206 (9%)

Query: 25  IQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQV 84
           ++ L   RK  + F    +    +  +Y   L   SR+    Q E+   +R L+   ++ 
Sbjct: 251 LERLEEERKQMEAFRQKAELGRFLRHQYNAQL---SRRTQQIQEELEADRRILQALLEKE 307

Query: 85  DNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTMDAKKNY 144
           D   + H+   + +  +   M++  E+Q    +  E  +  + ++++ +  +  +A+   
Sbjct: 308 DESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEMWEKREAEWAR 367

Query: 145 EQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLDKV--- 201
           E+  RD+  +E    R         Q+++  K+  ++ A E+S K     I  L++V   
Sbjct: 368 ERSARDRLMSEVLTGR---------QQQIQEKIEQNRRAQEESLKHREQLIRNLEEVREL 418

Query: 202 --REEWQSEHIKAC--EAFEAQECER 223
             RE+ +SE +K+   +  EAQ  ER
Sbjct: 419 ARREKEESEKLKSARKQELEAQVAER 444



 Score = 28.5 bits (62), Expect = 8.8
 Identities = 38/167 (22%), Positives = 74/167 (44%), Gaps = 23/167 (13%)

Query: 99  REEARKMEEFREKQKLQRKKTELIMDAIHK------QKSLQFKKTMDAKKNYEQKCRDKD 152
           R E  ++EE R++ +  R+K EL     H+      +++ Q ++ ++A +   Q   +K+
Sbjct: 248 RWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEKE 307

Query: 153 EAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKA 212
           +  Q +  +       ++E++   +A  K A+E+  +        L  +  E      +A
Sbjct: 308 DESQRLHLA-------RREQVMADVAWMKQAIEEQLQLERAREAELQMLLRE------EA 354

Query: 213 CEAFEAQECE--RINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLE 257
            E +E +E E  R    R+ L   V    QQ +   E  EQ R++ E
Sbjct: 355 KEMWEKREAEWARERSARDRLMSEVLTGRQQQI--QEKIEQNRRAQE 399


>gi|14150056 trichoplein [Homo sapiens]
          Length = 498

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 43/206 (20%), Positives = 91/206 (44%), Gaps = 19/206 (9%)

Query: 25  IQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQV 84
           ++ L   RK  + F    +    +  +Y   L   SR+    Q E+   +R L+   ++ 
Sbjct: 251 LERLEEERKQMEAFRQKAELGRFLRHQYNAQL---SRRTQQIQEELEADRRILQALLEKE 307

Query: 85  DNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTMDAKKNY 144
           D   + H+   + +  +   M++  E+Q    +  E  +  + ++++ +  +  +A+   
Sbjct: 308 DESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEMWEKREAEWAR 367

Query: 145 EQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLDKV--- 201
           E+  RD+  +E    R         Q+++  K+  ++ A E+S K     I  L++V   
Sbjct: 368 ERSARDRLMSEVLTGR---------QQQIQEKIEQNRRAQEESLKHREQLIRNLEEVREL 418

Query: 202 --REEWQSEHIKAC--EAFEAQECER 223
             RE+ +SE +K+   +  EAQ  ER
Sbjct: 419 ARREKEESEKLKSARKQELEAQVAER 444



 Score = 28.5 bits (62), Expect = 8.8
 Identities = 38/167 (22%), Positives = 74/167 (44%), Gaps = 23/167 (13%)

Query: 99  REEARKMEEFREKQKLQRKKTELIMDAIHK------QKSLQFKKTMDAKKNYEQKCRDKD 152
           R E  ++EE R++ +  R+K EL     H+      +++ Q ++ ++A +   Q   +K+
Sbjct: 248 RWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRILQALLEKE 307

Query: 153 EAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKA 212
           +  Q +  +       ++E++   +A  K A+E+  +        L  +  E      +A
Sbjct: 308 DESQRLHLA-------RREQVMADVAWMKQAIEEQLQLERAREAELQMLLRE------EA 354

Query: 213 CEAFEAQECE--RINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLE 257
            E +E +E E  R    R+ L   V    QQ +   E  EQ R++ E
Sbjct: 355 KEMWEKREAEWARERSARDRLMSEVLTGRQQQI--QEKIEQNRRAQE 399


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 30/115 (26%), Positives = 63/115 (54%), Gaps = 9/115 (7%)

Query: 68   SEINTLKRALEV----FKQQVDNVAQCHIQLAQSLREEARKMEEFR-EKQKLQRKKTELI 122
            S++NT+K  LE      ++ +++  Q  +QL QSL+E+ ++M+EFR + +++    T+L 
Sbjct: 899  SQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLF 958

Query: 123  MDAIHKQKSLQFK----KTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKL 173
            ++   + KSLQ      KT   ++  + +  + D  ++   +S N+ N  ++  L
Sbjct: 959  LEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDL 1013



 Score = 28.5 bits (62), Expect = 8.8
 Identities = 25/109 (22%), Positives = 47/109 (43%), Gaps = 3/109 (2%)

Query: 69  EINTLKRALEVFKQQVD-NVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIH 127
           E NT+   L++ K +++  +     +L +   +  + +EE    + L     +L  + + 
Sbjct: 706 EKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLI 765

Query: 128 KQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVK 176
           K    +  +  + KKN EQ   D  E +  +S S  L   KQ  +L  K
Sbjct: 766 KLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSS--LEEQKQLTQLINK 812


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 62/274 (22%), Positives = 104/274 (37%), Gaps = 67/274 (24%)

Query: 30   NGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSE--------------INTLKR 75
            N  K C+  ED L E    EE   + + +L+ ++   Q+E              ++ L R
Sbjct: 1248 NLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSR 1307

Query: 76   ALEVFKQQVDNV-------AQCHIQLAQSLREEARKMEEFRE--------KQKLQRK--- 117
              + F QQ++ +        +    LA +L+      +  RE        K +LQR    
Sbjct: 1308 GKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSK 1367

Query: 118  --------KTELIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAV-SRSANLVNPK 168
                    +T+   DAI + + L+     +AKK   Q+ +D +E  +AV ++ A+L   K
Sbjct: 1368 ANSEVAQWRTKYETDAIQRTEELE-----EAKKKLAQRLQDAEEHVEAVNAKCASLEKTK 1422

Query: 169  QQ-----EKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECER 223
            Q+     E L + +  +  A    DK         DK+  EW+            Q+CE 
Sbjct: 1423 QRLQNEVEDLMIDVERTNAACAALDKKQR----NFDKILAEWK------------QKCEE 1466

Query: 224  INFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLE 257
             +    A       LS +       YE+    LE
Sbjct: 1467 THAELEASQKESRSLSTELFKIKNAYEESLDQLE 1500



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 36/121 (29%), Positives = 62/121 (51%), Gaps = 19/121 (15%)

Query: 43   KERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEA 102
            KE+ A++E + + L +L  +    + ++NTL +A    +QQVD+       L  SL +E 
Sbjct: 998  KEKKALQEAHQQTLDDLQAE----EDKVNTLTKAKIKLEQQVDD-------LEGSLEQEK 1046

Query: 103  R-KMEEFREKQKLQ---RKKTELIMDAIHKQKSLQFKKTMDAKKNYEQK-CRDKDEAEQA 157
            + +M+  R K+KL+   +   E  MD  + ++ L  K     KK +E    + K E EQA
Sbjct: 1047 KIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKL---KKKEFEMSGLQSKIEDEQA 1103

Query: 158  V 158
            +
Sbjct: 1104 L 1104



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 35/172 (20%), Positives = 74/172 (43%), Gaps = 18/172 (10%)

Query: 36   KEFEDFLKERAAIEERYGKD------LLNLSRKKPCGQSEINTLKRALEVFKQQVD-NVA 88
            K+  D  +E   I ER  +        + +++K+   ++E   ++R LE    Q +   A
Sbjct: 1138 KQRSDLSRELEEISERLEEAGGATSAQIEMNKKR---EAEFQKMRRDLEEATLQHEATAA 1194

Query: 89   QCHIQLAQSLREEARKMEEF-REKQKLQRKKTELIMDAIHKQKSLQFKKTMDAKKNYEQK 147
                + A S+ E   +++   R KQKL+++K+E+ M+      +++      AK N E+ 
Sbjct: 1195 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNME--TVSKAKGNLEKM 1252

Query: 148  CRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLD 199
            CR  ++    +         ++Q++L   L   +  ++     Y   +   D
Sbjct: 1253 CRALEDQLSEIK-----TKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKD 1299



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 25/172 (14%)

Query: 39   EDFLKERAAIEERYGK-----------DLLNLSRKKPCGQSEINTLKRALEVFKQQVDNV 87
            ++ LKE+ A+ ER               L    R +   + E+      +++   Q  ++
Sbjct: 1668 QEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSL 1727

Query: 88   AQCHIQLAQSLREEARKMEEF-REKQKLQRKKTELIMDAIHKQKSLQFKKTMDA-----K 141
                 +L   + +   +ME+  +E +  + K  + I DA    + L+ ++   A     K
Sbjct: 1728 INTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1787

Query: 142  KNYEQKCRD----KDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDK 189
            KN EQ  +D     DEAEQ   +       KQ +KL  ++   +  VE   K
Sbjct: 1788 KNLEQTVKDLQHRLDEAEQLALKGGK----KQIQKLEARVRELEGEVESEQK 1835



 Score = 28.9 bits (63), Expect = 6.7
 Identities = 28/119 (23%), Positives = 54/119 (45%), Gaps = 13/119 (10%)

Query: 97  SLREEARKMEEFREKQKLQRKKTELIMDAIHKQKS---LQFKKTMDAKKNYEQKC----R 149
           +++EE  K +E   K + +RK+ E  M  + ++K+   LQ +   D+  + E++C    +
Sbjct: 855 NMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIK 914

Query: 150 DKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIG----TLDKVREE 204
            K + E  +         + +E++  +L   K  +ED        I     TL KV +E
Sbjct: 915 TKIQLEAKIKEVTE--RAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 971


>gi|157785548 PAS domain containing 1 [Homo sapiens]
          Length = 773

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 30/112 (26%), Positives = 58/112 (51%), Gaps = 10/112 (8%)

Query: 65  CGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEE----FREKQKLQRKKTE 120
           CG S  N+LK   E+ +  V    Q  +Q  Q L+E+ R++ E     RE++K+Q++K  
Sbjct: 456 CGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQK-- 513

Query: 121 LIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEK 172
                + ++K LQ +K  + KK  EQ+ + K + ++       ++  + +E+
Sbjct: 514 ----KMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEE 561


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.130    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,172,852
Number of Sequences: 37866
Number of extensions: 542687
Number of successful extensions: 3962
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 367
Number of HSP's that attempted gapping in prelim test: 3054
Number of HSP's gapped (non-prelim): 1042
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.