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Search of human proteins with 16554621
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16554621 WD repeat domain 10 isoform 1 [Homo sapiens]
(1292 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16554621 WD repeat domain 10 isoform 1 [Homo sapiens] 2635 0.0
gi|16554623 WD repeat domain 10 isoform 2 [Homo sapiens] 2504 0.0
gi|16554619 WD repeat domain 10 isoform 3 [Homo sapiens] 2336 0.0
gi|16554625 WD repeat domain 10 isoform 4 [Homo sapiens] 2127 0.0
gi|41146563 PREDICTED: hypothetical protein LOC653712 [Homo sapi... 184 4e-46
gi|169165594 PREDICTED: hypothetical LOC653712 [Homo sapiens] 183 8e-46
gi|88971034 PREDICTED: hypothetical LOC653712 [Homo sapiens] 183 8e-46
gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens] 64 7e-10
gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens] 64 7e-10
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 57 1e-07
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 57 1e-07
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 57 1e-07
gi|26665869 WD repeat domain 51B [Homo sapiens] 57 1e-07
gi|55743151 WD repeat domain 19 [Homo sapiens] 56 2e-07
gi|46358428 selective LIM binding factor homolog [Homo sapiens] 54 1e-06
gi|21071067 TBP-associated factor 5 [Homo sapiens] 53 2e-06
gi|16554629 WD repeat domain 5 [Homo sapiens] 52 3e-06
gi|16554627 WD repeat domain 5 [Homo sapiens] 52 3e-06
gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)... 52 3e-06
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H... 52 5e-06
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho... 52 5e-06
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 51 6e-06
gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo ... 51 6e-06
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 50 1e-05
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 50 1e-05
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 50 1e-05
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 50 1e-05
gi|23199987 WD repeat domain 5B [Homo sapiens] 50 2e-05
gi|32483359 apoptotic peptidase activating factor 1 isoform c [H... 49 4e-05
gi|7108333 apoptotic peptidase activating factor 1 isoform a [Ho... 49 4e-05
>gi|16554621 WD repeat domain 10 isoform 1 [Homo sapiens]
Length = 1292
Score = 2635 bits (6829), Expect = 0.0
Identities = 1292/1292 (100%), Positives = 1292/1292 (100%)
Query: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA
Sbjct: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
Query: 61 YAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKA 120
YAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKA
Sbjct: 61 YAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKA 120
Query: 121 PKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKH 180
PKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKH
Sbjct: 121 PKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKH 180
Query: 181 KSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSSR 240
KSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSSR
Sbjct: 181 KSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSSR 240
Query: 241 WESFWMNRENEDAEDVIVNRYIQEIPSTLKSAVYSSQGSEAEEEEPEEEDDSPRDDNLEE 300
WESFWMNRENEDAEDVIVNRYIQEIPSTLKSAVYSSQGSEAEEEEPEEEDDSPRDDNLEE
Sbjct: 241 WESFWMNRENEDAEDVIVNRYIQEIPSTLKSAVYSSQGSEAEEEEPEEEDDSPRDDNLEE 300
Query: 301 RNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTK 360
RNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTK
Sbjct: 301 RNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTK 360
Query: 361 DGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSM 420
DGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSM
Sbjct: 361 DGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSM 420
Query: 421 TDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEK 480
TDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEK
Sbjct: 421 TDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEK 480
Query: 481 IIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLL 540
IIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLL
Sbjct: 481 IIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLL 540
Query: 541 VGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELL 600
VGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELL
Sbjct: 541 VGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELL 600
Query: 601 FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFS 660
FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFS
Sbjct: 601 FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFS 660
Query: 661 ISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRV 720
ISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRV
Sbjct: 661 ISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRV 720
Query: 721 QDLRYLELISSIEERKKQGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDL 780
QDLRYLELISSIEERKKQGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDL
Sbjct: 721 QDLRYLELISSIEERKKQGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDL 780
Query: 781 CMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGW 840
CMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGW
Sbjct: 781 CMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGW 840
Query: 841 VDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDE 900
VDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDE
Sbjct: 841 VDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDE 900
Query: 901 AFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAES 960
AFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAES
Sbjct: 901 AFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAES 960
Query: 961 RFNDAAYYYWMLSMQCLDIAQDPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVH 1020
RFNDAAYYYWMLSMQCLDIAQDPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVH
Sbjct: 961 RFNDAAYYYWMLSMQCLDIAQDPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVH 1020
Query: 1021 RPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPA 1080
RPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPA
Sbjct: 1021 RPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPA 1080
Query: 1081 RFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYD 1140
RFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYD
Sbjct: 1081 RFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYD 1140
Query: 1141 VLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDP 1200
VLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDP
Sbjct: 1141 VLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDP 1200
Query: 1201 FTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPS 1260
FTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPS
Sbjct: 1201 FTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPS 1260
Query: 1261 CFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1292
CFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP
Sbjct: 1261 CFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1292
>gi|16554623 WD repeat domain 10 isoform 2 [Homo sapiens]
Length = 1241
Score = 2504 bits (6490), Expect = 0.0
Identities = 1240/1292 (95%), Positives = 1241/1292 (96%), Gaps = 51/1292 (3%)
Query: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA
Sbjct: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
Query: 61 YAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKA 120
YAKDGKRFASGSADKSVIIWTSKLEGILKYT
Sbjct: 61 YAKDGKRFASGSADKSVIIWTSKLEGILKYT----------------------------- 91
Query: 121 PKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKH 180
HNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKH
Sbjct: 92 ----------------------HNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKH 129
Query: 181 KSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSSR 240
KSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSSR
Sbjct: 130 KSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSSR 189
Query: 241 WESFWMNRENEDAEDVIVNRYIQEIPSTLKSAVYSSQGSEAEEEEPEEEDDSPRDDNLEE 300
WESFWMNRENEDAEDVIVNRYIQEIPSTLKSAVYSSQGSEAEEEEPEEEDDSPRDDNLEE
Sbjct: 190 WESFWMNRENEDAEDVIVNRYIQEIPSTLKSAVYSSQGSEAEEEEPEEEDDSPRDDNLEE 249
Query: 301 RNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTK 360
RNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTK
Sbjct: 250 RNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTK 309
Query: 361 DGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSM 420
DGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSM
Sbjct: 310 DGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSM 369
Query: 421 TDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEK 480
TDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEK
Sbjct: 370 TDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEK 429
Query: 481 IIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLL 540
IIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLL
Sbjct: 430 IIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLL 489
Query: 541 VGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELL 600
VGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELL
Sbjct: 490 VGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELL 549
Query: 601 FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFS 660
FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFS
Sbjct: 550 FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFS 609
Query: 661 ISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRV 720
ISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRV
Sbjct: 610 ISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRV 669
Query: 721 QDLRYLELISSIEERKKQGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDL 780
QDLRYLELISSIEERKK+GETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDL
Sbjct: 670 QDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDL 729
Query: 781 CMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGW 840
CMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGW
Sbjct: 730 CMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGW 789
Query: 841 VDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDE 900
VDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDE
Sbjct: 790 VDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDE 849
Query: 901 AFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAES 960
AFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAES
Sbjct: 850 AFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAES 909
Query: 961 RFNDAAYYYWMLSMQCLDIAQDPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVH 1020
RFNDAAYYYWMLSMQCLDIAQDPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVH
Sbjct: 910 RFNDAAYYYWMLSMQCLDIAQDPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVH 969
Query: 1021 RPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPA 1080
RPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPA
Sbjct: 970 RPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPA 1029
Query: 1081 RFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYD 1140
RFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYD
Sbjct: 1030 RFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYD 1089
Query: 1141 VLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDP 1200
VLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDP
Sbjct: 1090 VLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDP 1149
Query: 1201 FTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPS 1260
FTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPS
Sbjct: 1150 FTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPS 1209
Query: 1261 CFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1292
CFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP
Sbjct: 1210 CFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1241
>gi|16554619 WD repeat domain 10 isoform 3 [Homo sapiens]
Length = 1182
Score = 2336 bits (6055), Expect = 0.0
Identities = 1174/1292 (90%), Positives = 1177/1292 (91%), Gaps = 110/1292 (8%)
Query: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA
Sbjct: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
Query: 61 YAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKA 120
YAKDGKRFASGSADKSVIIWTSKLEGILKYT
Sbjct: 61 YAKDGKRFASGSADKSVIIWTSKLEGILKYT----------------------------- 91
Query: 121 PKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKH 180
HNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKH
Sbjct: 92 ----------------------HNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKH 129
Query: 181 KSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSSR 240
KSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPI
Sbjct: 130 KSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPI---------- 179
Query: 241 WESFWMNRENEDAEDVIVNRYIQEIPSTLKSAVYSSQGSEAEEEEPEEEDDSPRDDNLEE 300
W W + + EE
Sbjct: 180 WSICW-------------------------------------------------NPSREE 190
Query: 301 RNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTK 360
RNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTK
Sbjct: 191 RNDILAVADWGQKVSFYQLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTK 250
Query: 361 DGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSM 420
DGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSM
Sbjct: 251 DGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSM 310
Query: 421 TDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEK 480
TDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEK
Sbjct: 311 TDVIVQHLITEQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEK 370
Query: 481 IIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLL 540
IIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLL
Sbjct: 371 IIKKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLL 430
Query: 541 VGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELL 600
VGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELL
Sbjct: 431 VGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELL 490
Query: 601 FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFS 660
FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFS
Sbjct: 491 FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFS 550
Query: 661 ISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRV 720
ISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRV
Sbjct: 551 ISAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRV 610
Query: 721 QDLRYLELISSIEERKKQGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDL 780
QDLRYLELISSIEERKK+GETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDL
Sbjct: 611 QDLRYLELISSIEERKKRGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDL 670
Query: 781 CMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGW 840
CMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGW
Sbjct: 671 CMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGW 730
Query: 841 VDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDE 900
VDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDE
Sbjct: 731 VDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDE 790
Query: 901 AFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAES 960
AFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAES
Sbjct: 791 AFALGEKHPEFKDDIYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAES 850
Query: 961 RFNDAAYYYWMLSMQCLDIAQDPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVH 1020
RFNDAAYYYWMLSMQCLDIAQDPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVH
Sbjct: 851 RFNDAAYYYWMLSMQCLDIAQDPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVH 910
Query: 1021 RPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPA 1080
RPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPA
Sbjct: 911 RPETLFNISRFLLHSLPKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPA 970
Query: 1081 RFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYD 1140
RFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYD
Sbjct: 971 RFQKSIELGTLTIRAKPFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYD 1030
Query: 1141 VLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDP 1200
VLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDP
Sbjct: 1031 VLHLVEFYLEEGITDEEAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDP 1090
Query: 1201 FTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPS 1260
FTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPS
Sbjct: 1091 FTAKLSFEQGGSEFVPVVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPS 1150
Query: 1261 CFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1292
CFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP
Sbjct: 1151 CFQMFHSEDYELLVLQHGCCPYCRRCKDDPGP 1182
>gi|16554625 WD repeat domain 10 isoform 4 [Homo sapiens]
Length = 1131
Score = 2127 bits (5511), Expect = 0.0
Identities = 1065/1156 (92%), Positives = 1072/1156 (92%), Gaps = 72/1156 (6%)
Query: 138 QPGQKHNDAIQCVSYNPITHQLASCSSSDFGLWSPEQKSVSKHKSSSKIICCSWTNDGQY 197
QP + H D + CV+Y + GLWSPEQKSVSKHKSSSKIICCSWTNDGQY
Sbjct: 47 QPLKGHKDTVYCVAY------------AKDGLWSPEQKSVSKHKSSSKIICCSWTNDGQY 94
Query: 198 LALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWNPSSRWESFWMNRENEDAEDVI 257
LALGMFNGIISIRNKNGEEKVKIERPGGSLSPI W W
Sbjct: 95 LALGMFNGIISIRNKNGEEKVKIERPGGSLSPI----------WSICW------------ 132
Query: 258 VNRYIQEIPSTLKSAVYSSQGSEAEEEEPEEEDDSPRDDNLEERNDILAVADWGQKVSFY 317
+ + EERNDILAVADWGQKVSFY
Sbjct: 133 -------------------------------------NPSREERNDILAVADWGQKVSFY 155
Query: 318 QLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRLGTVGEQNSWVWT 377
QLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRLGTVGEQNSWVWT
Sbjct: 156 QLSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRLGTVGEQNSWVWT 215
Query: 378 CQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIK 437
CQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIK
Sbjct: 216 CQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDSMTDVIVQHLITEQKVRIK 275
Query: 438 CKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEKIIKKFECNLLVVCANHI 497
CKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEKIIKKFECNLLVVCANHI
Sbjct: 276 CKELVKKIAIYRNRLAIQLPEKILIYELYSEDLSDMHYRVKEKIIKKFECNLLVVCANHI 335
Query: 498 ILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNLF 557
ILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNLF
Sbjct: 336 ILCQEKRLQCLSFSGVKEREWQMESLIRYIKVIGGPPGREGLLVGLKNGQILKIFVDNLF 395
Query: 558 AIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCED 617
AIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCED
Sbjct: 396 AIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCED 455
Query: 618 MLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQSAPMYQYLD 677
MLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQSAPMYQYLD
Sbjct: 456 MLCFSGGGYLNIKASTFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQSAPMYQYLD 515
Query: 678 RKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKK 737
RKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKK
Sbjct: 516 RKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKK 575
Query: 738 QGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKE 797
+GETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKE
Sbjct: 576 RGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKE 635
Query: 798 TKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAERE 857
TKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAERE
Sbjct: 636 TKMLITKQADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAERE 695
Query: 858 PLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFKDDIYM 917
PLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFKDDIYM
Sbjct: 696 PLLLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFKDDIYM 755
Query: 918 PYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAESRFNDAAYYYWMLSMQCL 977
PYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAESRFNDAAYYYWMLSMQCL
Sbjct: 756 PYAQWLAENDRFEEAQKAFHKAGRQREAVQVLEQLTNNAVAESRFNDAAYYYWMLSMQCL 815
Query: 978 DIAQ-DPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVHRPETLFNISRFLLHSL 1036
DIAQ DPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVHRPETLFNISRFLLHSL
Sbjct: 816 DIAQADPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVHRPETLFNISRFLLHSL 875
Query: 1037 PKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPARFQKSIELGTLTIRAK 1096
PKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPARFQKSIELGTLTIRAK
Sbjct: 876 PKDTPSGISKVKILFTLAKQSKALGAYRLARHAYDKLRGLYIPARFQKSIELGTLTIRAK 935
Query: 1097 PFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYDVLHLVEFYLEEGITDE 1156
PFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYDVLHLVEFYLEEGITDE
Sbjct: 936 PFHDSEELVPLCYRCSTNNPLLNNLGNVCINCRQPFIFSASSYDVLHLVEFYLEEGITDE 995
Query: 1157 EAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDPFTAKLSFEQGGSEFVP 1216
EAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDPFTAKLSFEQGGSEFVP
Sbjct: 996 EAISLIDLEVLRPKRDDRQLEIANNSSQILRLVETKDSIGDEDPFTAKLSFEQGGSEFVP 1055
Query: 1217 VVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQ 1276
VVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQ
Sbjct: 1056 VVVSRLVLRSMSRRDVLIKRWPPPLRWQYFRSLLPDASITMCPSCFQMFHSEDYELLVLQ 1115
Query: 1277 HGCCPYCRRCKDDPGP 1292
HGCCPYCRRCKDDPGP
Sbjct: 1116 HGCCPYCRRCKDDPGP 1131
Score = 145 bits (366), Expect = 2e-34
Identities = 97/251 (38%), Positives = 131/251 (52%), Gaps = 37/251 (14%)
Query: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA
Sbjct: 1 MRAVLTWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVA 60
Query: 61 YAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVM-------SSLHLHL-PFLGLHKTV 112
YAKDG +W+ + + + K+ S S + +L L F G+
Sbjct: 61 YAKDG-------------LWSPEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIR 107
Query: 113 RVTATDKAP-KGQGGRIDCLRPSVQNQPGQKHNDAIQCVSYNPITHQLASCSSSDFGLWS 171
+K + GG + + N ++ ND + + +
Sbjct: 108 NKNGEEKVKIERPGGSLSPIWSICWNPSREERNDILAVADW-----------GQKVSFYQ 156
Query: 172 PEQKSVSKHKSSSKIICC-SWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPI 230
K + K ++ + CC S+ G+Y+ LG + +S+ K+G V++ G S +
Sbjct: 157 LSGKQIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDG---VRLGTVGEQNSWV 213
Query: 231 WSICWNPSSRW 241
W+ P S +
Sbjct: 214 WTCQAKPDSNY 224
>gi|41146563 PREDICTED: hypothetical protein LOC653712 [Homo
sapiens]
Length = 121
Score = 184 bits (468), Expect = 4e-46
Identities = 92/96 (95%), Positives = 92/96 (95%), Gaps = 1/96 (1%)
Query: 573 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKAS 632
MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGG LNIKAS
Sbjct: 1 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGNLNIKAS 60
Query: 633 TFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQ 668
FPVH QKLQGFVVGYNGSKIFCLHVF ISAVEVPQ
Sbjct: 61 IFPVHWQKLQGFVVGYNGSKIFCLHVF-ISAVEVPQ 95
>gi|169165594 PREDICTED: hypothetical LOC653712 [Homo sapiens]
Length = 121
Score = 183 bits (465), Expect = 8e-46
Identities = 91/96 (94%), Positives = 92/96 (95%), Gaps = 1/96 (1%)
Query: 573 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKAS 632
MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGG LNIKAS
Sbjct: 1 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGNLNIKAS 60
Query: 633 TFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQ 668
FPVH QKLQGFVVGYNGSKIFCLHVF ISA+EVPQ
Sbjct: 61 IFPVHWQKLQGFVVGYNGSKIFCLHVF-ISALEVPQ 95
>gi|88971034 PREDICTED: hypothetical LOC653712 [Homo sapiens]
Length = 121
Score = 183 bits (465), Expect = 8e-46
Identities = 91/96 (94%), Positives = 92/96 (95%), Gaps = 1/96 (1%)
Query: 573 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKAS 632
MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGG LNIKAS
Sbjct: 1 MSASRKKLAVVDENDTCLVYDIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGNLNIKAS 60
Query: 633 TFPVHRQKLQGFVVGYNGSKIFCLHVFSISAVEVPQ 668
FPVH QKLQGFVVGYNGSKIFCLHVF ISA+EVPQ
Sbjct: 61 IFPVHWQKLQGFVVGYNGSKIFCLHVF-ISALEVPQ 95
>gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens]
Length = 1170
Score = 64.3 bits (155), Expect = 7e-10
Identities = 90/446 (20%), Positives = 181/446 (40%), Gaps = 37/446 (8%)
Query: 539 LLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTK- 597
L+VG ++G I + + N+ I L ++ + +LA++D + +D+D +
Sbjct: 506 LIVGRESGTIQRYSLPNVGLIQKYSLNCRAYQLSLNCNSSRLAIIDISGVLTFFDLDARV 565
Query: 598 ----------ELL-FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVV 646
ELL + + + W D+ + + + P + G++
Sbjct: 566 TDSTGQQVVGELLKLERRDVWDMKWAKDNPDLFAMMEKTRMYVFRNLDPEEPIQTSGYIC 625
Query: 647 GYNGSKIFCLHVFSI-SAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTD--------- 696
+ +I + + I E P + + R L I +G+ D
Sbjct: 626 NFEDLEIKSVLLDEILKDPEHPNKDYLINFEIRSLRDSRALIEKVGIKDASQFIEDNPHP 685
Query: 697 --WRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKKQGE-TNNDLFLADVFSY 753
WR LA AL+ LD TA++AF+R +D + ++ + K+ G+ + + A+V Y
Sbjct: 686 RLWRLLAEAALQKLDLYTAEQAFVRCKDYQGIKFV------KRLGKLLSESMKQAEVVGY 739
Query: 754 QGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFL--GSGDPKETKMLITKQA--DWA 809
G+F EA + Y +LA+ + L + L GSGD ++ + A D+
Sbjct: 740 FGRFEEAERTYLEMDRRDLAIGLRLKLGDWFRVLQLLKTGSGDADDSLLEQANNAIGDYF 799
Query: 810 RNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKL 869
+ ++ AV+ Y+ + E + L ++A L + + L A ++
Sbjct: 800 ADRQKWLNAVQYYVQGRNQERLAECYYMLEDYEGLENLAISLPE-NHKLLPEIAQMFVRV 858
Query: 870 DSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFK-DDIYMPYAQWLAENDR 928
A +LK K+ V V +W++A L + H + + YA L E ++
Sbjct: 859 GMCEQAVTAFLKCSQPKAAVDTCVHLNQWNKAVELAKNHSMKEIGSLLARYASHLLEKNK 918
Query: 929 FEEAQKAFHKAGRQREAVQVLEQLTN 954
+A + + KA +A +++ ++ +
Sbjct: 919 TLDAIELYRKANYFFDAAKLMFKIAD 944
>gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens]
Length = 1181
Score = 64.3 bits (155), Expect = 7e-10
Identities = 90/446 (20%), Positives = 181/446 (40%), Gaps = 37/446 (8%)
Query: 539 LLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDENDTCLVYDIDTK- 597
L+VG ++G I + + N+ I L ++ + +LA++D + +D+D +
Sbjct: 517 LIVGRESGTIQRYSLPNVGLIQKYSLNCRAYQLSLNCNSSRLAIIDISGVLTFFDLDARV 576
Query: 598 ----------ELL-FQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGFVV 646
ELL + + + W D+ + + + P + G++
Sbjct: 577 TDSTGQQVVGELLKLERRDVWDMKWAKDNPDLFAMMEKTRMYVFRNLDPEEPIQTSGYIC 636
Query: 647 GYNGSKIFCLHVFSI-SAVEVPQSAPMYQYLDRKLFKEAYQIACLGVTDTD--------- 696
+ +I + + I E P + + R L I +G+ D
Sbjct: 637 NFEDLEIKSVLLDEILKDPEHPNKDYLINFEIRSLRDSRALIEKVGIKDASQFIEDNPHP 696
Query: 697 --WRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIEERKKQGE-TNNDLFLADVFSY 753
WR LA AL+ LD TA++AF+R +D + ++ + K+ G+ + + A+V Y
Sbjct: 697 RLWRLLAEAALQKLDLYTAEQAFVRCKDYQGIKFV------KRLGKLLSESMKQAEVVGY 750
Query: 754 QGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFL--GSGDPKETKMLITKQA--DWA 809
G+F EA + Y +LA+ + L + L GSGD ++ + A D+
Sbjct: 751 FGRFEEAERTYLEMDRRDLAIGLRLKLGDWFRVLQLLKTGSGDADDSLLEQANNAIGDYF 810
Query: 810 RNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKL 869
+ ++ AV+ Y+ + E + L ++A L + + L A ++
Sbjct: 811 ADRQKWLNAVQYYVQGRNQERLAECYYMLEDYEGLENLAISLPE-NHKLLPEIAQMFVRV 869
Query: 870 DSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFK-DDIYMPYAQWLAENDR 928
A +LK K+ V V +W++A L + H + + YA L E ++
Sbjct: 870 GMCEQAVTAFLKCSQPKAAVDTCVHLNQWNKAVELAKNHSMKEIGSLLARYASHLLEKNK 929
Query: 929 FEEAQKAFHKAGRQREAVQVLEQLTN 954
+A + + KA +A +++ ++ +
Sbjct: 930 TLDAIELYRKANYFFDAAKLMFKIAD 955
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 56.6 bits (135), Expect = 1e-07
Identities = 27/72 (37%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 15 INDIAFKPDGTQLILAAG-SRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
+N ++F P G LI A+ S L + D +G LL L GH+ VA+++ G+ FASG +
Sbjct: 194 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGS 253
Query: 74 DKSVIIWTSKLE 85
D+ V++W S +
Sbjct: 254 DEQVMVWKSNFD 265
Score = 42.4 bits (98), Expect = 0.003
Identities = 21/54 (38%), Positives = 29/54 (53%)
Query: 33 SRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEG 86
S L+V+ + GHKD V CV ++ G ASGS DK+V IW ++G
Sbjct: 3 SCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKG 56
Score = 36.2 bits (82), Expect = 0.21
Identities = 46/223 (20%), Positives = 86/223 (38%), Gaps = 16/223 (7%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
+ + F DG + A+ + + V+ T L L H + V C ++ DG+ S S
Sbjct: 68 VRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASD 127
Query: 74 DKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKAPKGQGGRIDCLRP 133
DK+V +W + S+ ++ F + D K R L
Sbjct: 128 DKTVKLWDKSSRECVH--SYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLL- 184
Query: 134 SVQNQPGQKHNDAIQCVSYNPITHQLASCSS-SDFGLWSPEQKSV--SKHKSSSKIICCS 190
Q Q H+ A+ +S++P + L + SS S + + + + H +
Sbjct: 185 ----QHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVA 240
Query: 191 WTNDGQYLALGMFNGIISIRNKNGE-----EKVKIERPGGSLS 228
++ G+Y A G + + + N + E K+ RP +L+
Sbjct: 241 FSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLA 283
Score = 33.9 bits (76), Expect = 1.0
Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 16/90 (17%)
Query: 6 TWRDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKG-------HKDTVYC 58
T A C+N F P G +LA+GSR D + + +KG H TV
Sbjct: 20 TGHKDAVTCVN---FSPSGH--LLASGSR----DKTVRIWVPNVKGESTVFRAHTATVRS 70
Query: 59 VAYAKDGKRFASGSADKSVIIWTSKLEGIL 88
V + DG+ F + S DK+V +W + + L
Sbjct: 71 VHFCSDGQSFVTASDDKTVKVWATHRQKFL 100
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 56.6 bits (135), Expect = 1e-07
Identities = 27/72 (37%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 15 INDIAFKPDGTQLILAAG-SRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
+N ++F P G LI A+ S L + D +G LL L GH+ VA+++ G+ FASG +
Sbjct: 232 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGS 291
Query: 74 DKSVIIWTSKLE 85
D+ V++W S +
Sbjct: 292 DEQVMVWKSNFD 303
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/61 (39%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 29 LAAGSR---LLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLE 85
LA+GS L+V+ + GHKD V CV ++ G ASGS DK+V IW ++
Sbjct: 34 LASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93
Query: 86 G 86
G
Sbjct: 94 G 94
Score = 41.6 bits (96), Expect = 0.005
Identities = 34/138 (24%), Positives = 51/138 (36%), Gaps = 50/138 (36%)
Query: 42 DGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHL 101
D +L + KGH+D V CV ++ + K+ ASGS D +++W K +
Sbjct: 8 DPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQS--------------- 52
Query: 102 HLPFLGLHKTVRVTATDKAPKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSYNPITHQLAS 161
+ R T H DA+ CV+++P H LAS
Sbjct: 53 --------RAYRFTG--------------------------HKDAVTCVNFSPSGHLLAS 78
Query: 162 CS-SSDFGLWSPEQKSVS 178
S +W P K S
Sbjct: 79 GSRDKTVRIWVPNVKGES 96
Score = 36.2 bits (82), Expect = 0.21
Identities = 46/223 (20%), Positives = 86/223 (38%), Gaps = 16/223 (7%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
+ + F DG + A+ + + V+ T L L H + V C ++ DG+ S S
Sbjct: 106 VRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASD 165
Query: 74 DKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKAPKGQGGRIDCLRP 133
DK+V +W + S+ ++ F + D K R L
Sbjct: 166 DKTVKLWDKSSRECVH--SYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLL- 222
Query: 134 SVQNQPGQKHNDAIQCVSYNPITHQLASCSS-SDFGLWSPEQKSV--SKHKSSSKIICCS 190
Q Q H+ A+ +S++P + L + SS S + + + + H +
Sbjct: 223 ----QHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVA 278
Query: 191 WTNDGQYLALGMFNGIISIRNKNGE-----EKVKIERPGGSLS 228
++ G+Y A G + + + N + E K+ RP +L+
Sbjct: 279 FSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLA 321
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 56.6 bits (135), Expect = 1e-07
Identities = 27/72 (37%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 15 INDIAFKPDGTQLILAAG-SRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
+N ++F P G LI A+ S L + D +G LL L GH+ VA+++ G+ FASG +
Sbjct: 232 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGS 291
Query: 74 DKSVIIWTSKLE 85
D+ V++W S +
Sbjct: 292 DEQVMVWKSNFD 303
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/61 (39%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 29 LAAGSR---LLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLE 85
LA+GS L+V+ + GHKD V CV ++ G ASGS DK+V IW ++
Sbjct: 34 LASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93
Query: 86 G 86
G
Sbjct: 94 G 94
Score = 41.6 bits (96), Expect = 0.005
Identities = 34/138 (24%), Positives = 51/138 (36%), Gaps = 50/138 (36%)
Query: 42 DGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHL 101
D +L + KGH+D V CV ++ + K+ ASGS D +++W K +
Sbjct: 8 DPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQS--------------- 52
Query: 102 HLPFLGLHKTVRVTATDKAPKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSYNPITHQLAS 161
+ R T H DA+ CV+++P H LAS
Sbjct: 53 --------RAYRFTG--------------------------HKDAVTCVNFSPSGHLLAS 78
Query: 162 CS-SSDFGLWSPEQKSVS 178
S +W P K S
Sbjct: 79 GSRDKTVRIWVPNVKGES 96
Score = 36.2 bits (82), Expect = 0.21
Identities = 46/223 (20%), Positives = 86/223 (38%), Gaps = 16/223 (7%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
+ + F DG + A+ + + V+ T L L H + V C ++ DG+ S S
Sbjct: 106 VRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASD 165
Query: 74 DKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKAPKGQGGRIDCLRP 133
DK+V +W + S+ ++ F + D K R L
Sbjct: 166 DKTVKLWDKSSRECVH--SYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLL- 222
Query: 134 SVQNQPGQKHNDAIQCVSYNPITHQLASCSS-SDFGLWSPEQKSV--SKHKSSSKIICCS 190
Q Q H+ A+ +S++P + L + SS S + + + + H +
Sbjct: 223 ----QHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVA 278
Query: 191 WTNDGQYLALGMFNGIISIRNKNGE-----EKVKIERPGGSLS 228
++ G+Y A G + + + N + E K+ RP +L+
Sbjct: 279 FSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLA 321
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 56.6 bits (135), Expect = 1e-07
Identities = 27/72 (37%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
+N I+F P G LI A+ L + D +G L+ L+GH V+ V+++K G+ FASG A
Sbjct: 231 VNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGA 290
Query: 74 DKSVIIWTSKLE 85
D V++W + +
Sbjct: 291 DTQVLLWRTNFD 302
Score = 40.0 bits (92), Expect = 0.014
Identities = 37/172 (21%), Positives = 68/172 (39%), Gaps = 9/172 (5%)
Query: 15 INDIAFKPDGTQLILAAGSR-LLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
I + P+G QL A+ L++++ GHKD V V ++ G AS S
Sbjct: 21 ITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASR 80
Query: 74 DKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKAPKGQGGRIDCLRP 133
D++V +W G K++ + ++ + F + + + DK+ K
Sbjct: 81 DRTVRLWIPDKRG--KFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLY 138
Query: 134 SVQNQPGQKHNDAIQCVSYNPITHQLASCS-SSDFGLWSPEQKSVSKHKSSS 184
S+ +H ++C ++P + SCS +W K + S S
Sbjct: 139 SL-----YRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDS 185
Score = 39.7 bits (91), Expect = 0.019
Identities = 36/151 (23%), Positives = 63/151 (41%), Gaps = 8/151 (5%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
+ + F DG L A+ + + V+ L L H V C ++ DG+ S S
Sbjct: 105 VRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSE 164
Query: 74 DKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKAPKGQGGRIDCLRP 133
DK++ IW + + + S SV + + G T A Q ++ +R
Sbjct: 165 DKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSG-------TCIASAGSDQTVKVWDVRV 217
Query: 134 SVQNQPGQKHNDAIQCVSYNPITHQLASCSS 164
+ Q Q H+ + C+S++P + L + SS
Sbjct: 218 NKLLQHYQVHSGGVNCISFHPSGNYLITASS 248
Score = 36.2 bits (82), Expect = 0.21
Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 14/102 (13%)
Query: 2 RAVLTWRDKAEHCINDIA----------FKPDGTQLILAAGS--RLLVYDTSDGTLLQPL 49
+ + W + C+N+ + F P GT I +AGS + V+D LLQ
Sbjct: 166 KTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGT-CIASAGSDQTVKVWDVRVNKLLQHY 224
Query: 50 KGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYT 91
+ H V C+++ G + S+D ++ I LEG L YT
Sbjct: 225 QVHSGGVNCISFHPSGNYLITASSDGTLKI-LDLLEGRLIYT 265
Score = 30.8 bits (68), Expect = 8.8
Identities = 14/44 (31%), Positives = 24/44 (54%)
Query: 40 TSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSK 83
T D L + KGHK + + + +GK+ A+ S D +++W K
Sbjct: 5 TEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFK 48
>gi|55743151 WD repeat domain 19 [Homo sapiens]
Length = 1342
Score = 56.2 bits (134), Expect = 2e-07
Identities = 132/670 (19%), Positives = 256/670 (38%), Gaps = 85/670 (12%)
Query: 360 KDGVRLGTVGEQNSWVWTCQAKPDSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRDS 419
KD + + E+N + T D + + Q G++ + + R AY S
Sbjct: 307 KDMYVILNLDEENKGLGTLSWTDDGQLLALSTQRGSLHVFLTKLPILGDACSTRIAYLTS 366
Query: 420 MTDVIVQHLIT-EQKVRIKCKELVKKIAIYRNRLAIQLPEKILIYELYS---EDLSDMHY 475
+ +V V + + E + + +A+ LA+ + + Y L + L DM Y
Sbjct: 367 LLEVTVANPVEGELPITVSVDVEPNFVAVGLYHLAVGMNNRAWFYVLGENAVKKLKDMEY 426
Query: 476 RVKEKII--------KKFECNLLVVCANHIILCQEKRLQCLSFSGVKEREWQMESLIRYI 527
I FE + + IL ++ + F V ++
Sbjct: 427 LGTVASICLHSDYAAALFEGKVQLHLIESEILDAQEERETRLFPAVDDK----------C 476
Query: 528 KVIGGPPGREGLLVGLKNGQILKIFVDNLFAIVLLKQATAVRCLDMSASRKKLAVVDEND 587
+++ + L+ G G + ++++ + + +V+ + + +L +DE
Sbjct: 477 RILCHALTSDFLIYGTDTGVVQYFYIEDWQFVNDYRHPVSVKKIFPDPNGTRLVFIDEKS 536
Query: 588 TCLVY---DIDTKELLFQEPNANSVAWNTQCEDMLCFSGGGYLNIKASTFPVHRQKLQGF 644
VY + T E+ P V W D F Y + K T+ H+ +QG
Sbjct: 537 DGFVYCPVNDATYEIPDFSPTIKGVLWENWPMDKGVFIA--YDDDKVYTYVFHKDTIQGA 594
Query: 645 VVGYNGS---------------KIFC-------------LHVF--SISAVEVPQSAPMY- 673
V GS ++ C H F ++ + PM
Sbjct: 595 KVILAGSTKVPFAHKPLLLYNGELTCQTQSGKVNNIYLSTHGFLSNLKDTGPDELRPMLA 654
Query: 674 QYLDRKLFKEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRVQDLRYLELISSIE 733
Q L K F +A+++ + + W ELA L ++ E A + + R+ ++ ++ S+E
Sbjct: 655 QNLMLKRFSDAWEMCRILNDEAAWNELARACLHHMEVEFAIRVYRRIGNVG---IVMSLE 711
Query: 734 ERKKQGETNNDLFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSG 793
+ K G + +L + + ++ A LY S ALEM DL ++ A
Sbjct: 712 QIK--GIEDYNLLAGHLAMFTNDYNLAQDLYLASSCPIAALEMRRDLQHWDSALQLAKHL 769
Query: 794 DPKETKMLITK---QADWARNIKEPKAAVEMYISAGEHVKAIEICGDHGWVDMLI---DI 847
P + + + Q ++A + A E I+ G++ + E C G M I DI
Sbjct: 770 APDQIPFISKEYAIQLEFAGDYVNALAHYEKGIT-GDNKEHDEACLA-GVAQMSIRMGDI 827
Query: 848 ARKLDKAEREPLLL----CATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFA 903
R +++A + P + C L+ + AA+ Y K +++ ++ W +
Sbjct: 828 RRGVNQALKHPSRVLKRDCGAILENMKQFSEAAQLYEKGLYYDKAASVYIRSKNWAK--- 884
Query: 904 LGEKHPEFKDD-IYMPYAQWLAENDRFEEAQKAFHKAGRQREAVQV-LEQLTN-----NA 956
+G+ P I++ YA+ + R++EA A+ A + + +++ L+ L N N
Sbjct: 885 VGDLLPHVSSPKIHLQYAKAKEADGRYKEAVVAYENAKQWQSVIRIYLDHLNNPEKAVNI 944
Query: 957 VAESRFNDAA 966
V E++ D A
Sbjct: 945 VRETQSLDGA 954
Score = 38.5 bits (88), Expect = 0.042
Identities = 46/204 (22%), Positives = 83/204 (40%), Gaps = 29/204 (14%)
Query: 756 KFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEP 815
+F EAA+LY++ + + A +Y + D L + + K + KE
Sbjct: 855 QFSEAAQLYEKGLYYDKAASVYIRSKNWAKVGDLLPHVSSPKIHLQYAKAKEADGRYKE- 913
Query: 816 KAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYA 875
AV Y +A + I I DH L+ E+ ++ T + LD
Sbjct: 914 --AVVAYENAKQWQSVIRIYLDH------------LNNPEKAVNIVRET--QSLDGAKMV 957
Query: 876 AETYLKMGDLKSLVQLHVETQRWDEAFALGEKHPEFK------------DDIYMPYAQWL 923
A +L++GD S +Q V ++ +EAF L ++H + + ++ Y A +
Sbjct: 958 ARFFLQLGDYGSAIQFLVMSKCNNEAFTLAQQHNKMEIYADIIGSEDTTNEDYQSIALYF 1017
Query: 924 AENDRFEEAQKAFHKAGRQREAVQ 947
R+ +A K F G+ A++
Sbjct: 1018 EGEKRYLQAGKFFLLCGQYSRALK 1041
>gi|46358428 selective LIM binding factor homolog [Homo sapiens]
Length = 1749
Score = 53.5 bits (127), Expect = 1e-06
Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 22/235 (9%)
Query: 707 GLDFETAKKAFIRVQDLRYLELISSIEERKKQGETNNDLFLADVFSYQGKFHEAAKLYKR 766
GL + A+ R + L EL+ I +GE + A L+++
Sbjct: 777 GLPAKAARLVLTREELLANTELVEHITAALIKGEL---------------YERAGDLFEK 821
Query: 767 SGHENLALEMYTDLCMFEYAKDFLGSGDPKETKMLITKQADWARNIKEPKAAVEMYISAG 826
+ ALE Y F A + P E L D K+ AA+ YI A
Sbjct: 822 IHNPQKALECYRKGNAFMKAVELARLAFPVEVVKLEEAWGDHLVQQKQLDAAINHYIEAR 881
Query: 827 EHVKAIEIC-GDHGW--VDMLIDIARKLDKAEREPLLLCATYLKKLDSPGYAAETYLKMG 883
+KAIE G W ++D+ + ++ PL+ A + L A E Y K
Sbjct: 882 CSIKAIEAALGARQWKKAIYILDLQDRNTASKYYPLV--AQHYASLQEYEIAEELYTKGD 939
Query: 884 DLKSLVQLHVETQRWDEAFALGEK--HPEFKDDIYMPYAQWLAENDRFEEAQKAF 936
K + ++ + RW++A L K PE +Y+ AQ + + ++ EA++ +
Sbjct: 940 RTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQAQEMEKQGKYREAERLY 994
Score = 52.8 bits (125), Expect = 2e-06
Identities = 52/208 (25%), Positives = 91/208 (43%), Gaps = 31/208 (14%)
Query: 754 QGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDP---KETKMLITKQADWAR 810
QGK+ EA +LY +LA+ MY +++ +G P +T + + K+ +
Sbjct: 984 QGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELEAEG 1043
Query: 811 NIKEP----------KAAVEMYISAGEHVKAIEICGDHGWVDMLIDIARKLDKAEREPLL 860
++E KA V MY ++G +A + G + +A
Sbjct: 1044 RLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVARTQGGANAHKHVA------------ 1091
Query: 861 LCATYLKKLDSPGYAAETYL-KMGDLKSLVQLHVETQRWDEAFALGEKHPEFKD-DIYMP 918
YL G AA L K+G L++ V + ++ AF L + K ++++
Sbjct: 1092 ----YLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHLK 1147
Query: 919 YAQWLAENDRFEEAQKAFHKAGRQREAV 946
YA +L + +FEEA+ F +AG+ +EAV
Sbjct: 1148 YAMFLEDEGKFEEAEAEFIRAGKPKEAV 1175
Score = 35.0 bits (79), Expect = 0.46
Identities = 54/252 (21%), Positives = 102/252 (40%), Gaps = 33/252 (13%)
Query: 710 FETAKKAFIRVQDLRYLELI----SSIEERKKQGETNNDLFLADVFSYQGK-------FH 758
FE A+ FIR + L+ E ++ E ++ +A+V Q + F
Sbjct: 1158 FEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQ 1217
Query: 759 EAAKLYKRSGHENLALEMYTDLCMFEYA----KDFLGS---GDPKETKMLITKQADWARN 811
+A L R+ LAL Y + ++ A KD++ S +E + TK+ AR
Sbjct: 1218 KAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQEEYEREATKKG--ARG 1275
Query: 812 IKEPKAAVEMYISAGEHVKAIEI------CGDHGWVDMLIDIARKLD------KAEREPL 859
++ + AGE+ +A++ G+ G + A +L + E +
Sbjct: 1276 VEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAELSIKFLPPQRNMEVV 1335
Query: 860 LLCATYLKKLDSPGYAAETYLKMGDLKSLVQLHVETQRWDEAFALG-EKHPEFKDDIYMP 918
L L + AAE YL + +K + +E + W++A + E P ++D +
Sbjct: 1336 LAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYEDYVDQH 1395
Query: 919 YAQWLAENDRFE 930
Y ++L + +
Sbjct: 1396 YKEFLKNQGKVD 1407
Score = 31.6 bits (70), Expect = 5.1
Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 879 YLKMGDLKSLVQLHVETQRWDEAFALGEK--HPEFKDDIYMPYAQWLAENDRFEEAQKAF 936
+L+ ++ + ++ E RWDE A+ E HP + + Y QWL + + E A +
Sbjct: 702 FLEQNAVEEAMGMYQELHRWDECIAVAEAKGHPAL-EKLRRSYYQWLMDTQQEERAGELQ 760
Query: 937 HKAGRQREAVQV 948
G A+ +
Sbjct: 761 ESQGDGLAAISL 772
Score = 31.6 bits (70), Expect = 5.1
Identities = 29/107 (27%), Positives = 44/107 (41%), Gaps = 17/107 (15%)
Query: 745 LFLADVFSYQGKFHEAAKLYKRSGHENLALEMYTDLCMFEYAKDFLGSGDPKETKMLITK 804
+FL D +GKF EA + R+G A+ M+ +E A+ + DP ++
Sbjct: 1150 MFLED----EGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVG 1205
Query: 805 QADWARNIKE-------------PKAAVEMYISAGEHVKAIEICGDH 838
QA A K+ P A+ Y AG A+ IC D+
Sbjct: 1206 QARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDY 1252
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 53.1 bits (126), Expect = 2e-06
Identities = 26/67 (38%), Positives = 41/67 (61%), Gaps = 1/67 (1%)
Query: 15 INDIAFKPDGTQLILAA-GSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
I+ + F P+G L A R+L++D G ++ LKGH DTV + +++DG+ ASGS
Sbjct: 672 IHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSM 731
Query: 74 DKSVIIW 80
D +V +W
Sbjct: 732 DNTVRLW 738
Score = 37.4 bits (85), Expect = 0.094
Identities = 15/67 (22%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
+N F P+ + + R + ++D +G ++ GHK ++ + ++ +G+ A+G+
Sbjct: 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 689
Query: 74 DKSVIIW 80
D V++W
Sbjct: 690 DGRVLLW 696
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 52.4 bits (124), Expect = 3e-06
Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
I+D+A+ D L+ A+ + L ++D S G L+ LKGH + V+C + SGS
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSF 149
Query: 74 DKSVIIWTSKLEGILK 89
D+SV IW K LK
Sbjct: 150 DESVRIWDVKTGKCLK 165
Score = 41.2 bits (95), Expect = 0.006
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Query: 15 INDIAFKPDGTQLILAA-GSRLLVYDTSDGTLLQPLKGHKDTVYCV---AYAKDGKRFAS 70
++ + F P+G ++ A + L ++D S G L+ GHK+ YC+ GK S
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 276
Query: 71 GSADKSVIIWTSKLEGILK 89
GS D V IW + + I++
Sbjct: 277 GSEDNLVYIWNLQTKEIVQ 295
Score = 39.7 bits (91), Expect = 0.019
Identities = 19/67 (28%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
++ + F P+G L ++ +L+ ++ DG + + GHK + VA++ D S S
Sbjct: 48 VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD 107
Query: 74 DKSVIIW 80
DK++ IW
Sbjct: 108 DKTLKIW 114
Score = 32.0 bits (71), Expect = 3.9
Identities = 17/53 (32%), Positives = 23/53 (43%)
Query: 37 VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILK 89
++D G L+ L H D V V + +DG S S D IW + LK
Sbjct: 155 IWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLK 207
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 52.4 bits (124), Expect = 3e-06
Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
I+D+A+ D L+ A+ + L ++D S G L+ LKGH + V+C + SGS
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSF 149
Query: 74 DKSVIIWTSKLEGILK 89
D+SV IW K LK
Sbjct: 150 DESVRIWDVKTGKCLK 165
Score = 41.2 bits (95), Expect = 0.006
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Query: 15 INDIAFKPDGTQLILAA-GSRLLVYDTSDGTLLQPLKGHKDTVYCV---AYAKDGKRFAS 70
++ + F P+G ++ A + L ++D S G L+ GHK+ YC+ GK S
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 276
Query: 71 GSADKSVIIWTSKLEGILK 89
GS D V IW + + I++
Sbjct: 277 GSEDNLVYIWNLQTKEIVQ 295
Score = 39.7 bits (91), Expect = 0.019
Identities = 19/67 (28%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
++ + F P+G L ++ +L+ ++ DG + + GHK + VA++ D S S
Sbjct: 48 VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD 107
Query: 74 DKSVIIW 80
DK++ IW
Sbjct: 108 DKTLKIW 114
Score = 32.0 bits (71), Expect = 3.9
Identities = 17/53 (32%), Positives = 23/53 (43%)
Query: 37 VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILK 89
++D G L+ L H D V V + +DG S S D IW + LK
Sbjct: 155 IWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLK 207
>gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)
[Homo sapiens]
Length = 906
Score = 52.4 bits (124), Expect = 3e-06
Identities = 116/546 (21%), Positives = 211/546 (38%), Gaps = 88/546 (16%)
Query: 5 LTWRDKAEHCINDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAK 63
L +K +CI D D LI A RL+ ++D + T +Q L+GH V C ++
Sbjct: 181 LEGHEKGVNCI-DYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHP 239
Query: 64 DGKRFASGSADKSVIIW---TSKLEGILKY---TSWSVMSSLHLHLPFLGLHK-TVRVTA 116
+ +GS D +V IW T +LE L Y W V S + LG + ++ V
Sbjct: 240 ELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIVKL 299
Query: 117 TDKAP----KGQGGRIDCLRPSVQNQPGQKHNDA---------------------IQCVS 151
+ P G I VQ + DA Q +
Sbjct: 300 GREEPAMSMDANGKIIWAKHSEVQQANLKAMGDAEIKDGERLPLAVKDMGSCEIYPQTIQ 359
Query: 152 YNPITHQLASCSSSDFGLWSPEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISIRN 211
+NP + C ++ +++ ++KS +W +D A+ N I+ I
Sbjct: 360 HNPNGRFVVVCGDGEYIIYT---AMALRNKSFGSAQEFAWAHDSSEYAIRESNSIVKI-F 415
Query: 212 KNGEEKVKIERP--------GGSLSPIWSICWNPSSRWESFWMNRENE-DAEDVIVNRYI 262
KN +EK K +P GG L + S+ W++ + R E + + +
Sbjct: 416 KNFKEK-KSFKPDFGAESIYGGFLLGVRSVNGLAFYDWDNTELIRRIEIQPKHIFWSDSG 474
Query: 263 QEIPSTLKSAVYSSQGSEAEEEEPEEEDDSPRDDNLEERNDILAVADWGQKVSFYQLSGK 322
+ + + + + + + +E + +D +E+ ++L ++ +G
Sbjct: 475 ELVCIATEESFFILKYLSEKVLAAQETHEGVTEDGIEDAFEVLG------EIQEIVKTGL 528
Query: 323 QIGKDRALNFDPCCISYFTKGEYILLGGSDKQVSLFTKDGVRLGTVGEQNSWVWTCQAKP 382
+G ++Y+ GE + + D+ + L LG + P
Sbjct: 529 WVGDCFIYTSSVNRLNYYVGGEIVTIAHLDRTMYL-------LGYI-------------P 568
Query: 383 DSNYVVVGCQDGTISFYQLIFSTVHGLYKDRYAYRD-SMTDVIVQHLITEQKVRIKC--- 438
N + +G ++ I Y L+ S + Y+ RD SM D ++ + EQ+ R+
Sbjct: 569 KDNRLYLGDKELNIISYSLLVSVLE--YQTAVMRRDFSMADKVLPTIPKEQRTRVAHFLE 626
Query: 439 KELVKKIAI-------YRNRLAIQLPEKILIYELYSEDLSDMHYR-VKEKIIKKFECNLL 490
K+ K+ A+ +R LA+QL E + Y+L E S+ ++ + E I K + L
Sbjct: 627 KQGFKQQALTVSTDPEHRFELALQLGELKIAYQLAVEAESEQKWKQLAELAISKCQFGLA 686
Query: 491 VVCANH 496
C +H
Sbjct: 687 QECLHH 692
Score = 31.6 bits (70), Expect = 5.1
Identities = 24/97 (24%), Positives = 43/97 (44%), Gaps = 12/97 (12%)
Query: 682 KEAYQIACLGVTDTDWRELAMEALEGLDFETAKKAFIRVQDLRYL----------ELISS 731
K AYQ+A ++ W++LA A+ F A++ QD L +++
Sbjct: 655 KIAYQLAVEAESEQKWKQLAELAISKCQFGLAQECLHHAQDYGGLLLLATASGNANMVNK 714
Query: 732 IEERKKQGETNNDLFLADVFSYQGKFHEAAKLYKRSG 768
+ E ++ NN F++ + QGK +L R+G
Sbjct: 715 LAEGAERDGKNNVAFMS--YFLQGKVDACLELLIRTG 749
>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
sapiens]
Length = 1205
Score = 51.6 bits (122), Expect = 5e-06
Identities = 59/241 (24%), Positives = 98/241 (40%), Gaps = 37/241 (15%)
Query: 20 FKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVI 78
F DG ++ + L V+ G L +K H+D V C A++ D + A+ S DK V
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVK 682
Query: 79 IWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKAPKGQGGRIDC-LRPSVQN 137
IW S + G L +T ++ H + T G DC L+ N
Sbjct: 683 IWNS-MTGELVHTYDEHSEQVNCCHFTNSSHHLLLAT----------GSSDCFLKLWDLN 731
Query: 138 QPGQK-----HNDAIQCVSYNPITHQLASCSS-SDFGLW----SPEQKSVS--------- 178
Q + H +++ ++P LASCS+ LW + E+KS++
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE 791
Query: 179 --KHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWN 236
+ + CCSW+ DG + + N I N + + K+ G LS + + ++
Sbjct: 792 DPQEDMEVIVKCCSWSADGARIMVAAKNKIFL---WNTDSRSKVADCRGHLSWVHGVMFS 848
Query: 237 P 237
P
Sbjct: 849 P 849
Score = 43.1 bits (100), Expect = 0.002
Identities = 17/76 (22%), Positives = 44/76 (57%)
Query: 8 RDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKR 67
++ E + ++ DG ++++AA +++ +++T + + +GH V+ V ++ DG
Sbjct: 794 QEDMEVIVKCCSWSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 853
Query: 68 FASGSADKSVIIWTSK 83
F + S D+++ +W +K
Sbjct: 854 FLTSSDDQTIRLWETK 869
Score = 33.5 bits (75), Expect = 1.4
Identities = 38/166 (22%), Positives = 68/166 (40%), Gaps = 12/166 (7%)
Query: 49 LKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGL 108
++ H D VY +++DG+R AS ADK++ ++ K E K L F
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVF--KAETGEKLLEIKAHEDEVLCCAFSTD 668
Query: 109 HKTVRVTATDKAPKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSY-NPITHQLASCSSSD- 166
+ + + DK K L + +H++ + C + N H L + SSD
Sbjct: 669 DRFIATCSVDKKVKIWNSMTGELVHTY-----DEHSEQVNCCHFTNSSHHLLLATGSSDC 723
Query: 167 -FGLWSPEQKSV--SKHKSSSKIICCSWTNDGQYLALGMFNGIISI 209
LW QK + ++ + C ++ D + LA +G + +
Sbjct: 724 FLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKL 769
>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
sapiens]
Length = 1194
Score = 51.6 bits (122), Expect = 5e-06
Identities = 59/241 (24%), Positives = 98/241 (40%), Gaps = 37/241 (15%)
Query: 20 FKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVI 78
F DG ++ + L V+ G L +K H+D V C A++ D + A+ S DK V
Sbjct: 612 FSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVK 671
Query: 79 IWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKAPKGQGGRIDC-LRPSVQN 137
IW S + G L +T ++ H + T G DC L+ N
Sbjct: 672 IWNS-MTGELVHTYDEHSEQVNCCHFTNSSHHLLLAT----------GSSDCFLKLWDLN 720
Query: 138 QPGQK-----HNDAIQCVSYNPITHQLASCSS-SDFGLW----SPEQKSVS--------- 178
Q + H +++ ++P LASCS+ LW + E+KS++
Sbjct: 721 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE 780
Query: 179 --KHKSSSKIICCSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWN 236
+ + CCSW+ DG + + N I N + + K+ G LS + + ++
Sbjct: 781 DPQEDMEVIVKCCSWSADGARIMVAAKNKIFL---WNTDSRSKVADCRGHLSWVHGVMFS 837
Query: 237 P 237
P
Sbjct: 838 P 838
Score = 43.1 bits (100), Expect = 0.002
Identities = 17/76 (22%), Positives = 44/76 (57%)
Query: 8 RDKAEHCINDIAFKPDGTQLILAAGSRLLVYDTSDGTLLQPLKGHKDTVYCVAYAKDGKR 67
++ E + ++ DG ++++AA +++ +++T + + +GH V+ V ++ DG
Sbjct: 783 QEDMEVIVKCCSWSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSS 842
Query: 68 FASGSADKSVIIWTSK 83
F + S D+++ +W +K
Sbjct: 843 FLTSSDDQTIRLWETK 858
Score = 33.5 bits (75), Expect = 1.4
Identities = 38/166 (22%), Positives = 68/166 (40%), Gaps = 12/166 (7%)
Query: 49 LKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGL 108
++ H D VY +++DG+R AS ADK++ ++ K E K L F
Sbjct: 600 VRPHTDAVYHACFSEDGQRIASCGADKTLQVF--KAETGEKLLEIKAHEDEVLCCAFSTD 657
Query: 109 HKTVRVTATDKAPKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSY-NPITHQLASCSSSD- 166
+ + + DK K L + +H++ + C + N H L + SSD
Sbjct: 658 DRFIATCSVDKKVKIWNSMTGELVHTY-----DEHSEQVNCCHFTNSSHHLLLATGSSDC 712
Query: 167 -FGLWSPEQKSV--SKHKSSSKIICCSWTNDGQYLALGMFNGIISI 209
LW QK + ++ + C ++ D + LA +G + +
Sbjct: 713 FLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKL 758
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 51.2 bits (121), Expect = 6e-06
Identities = 54/220 (24%), Positives = 88/220 (40%), Gaps = 44/220 (20%)
Query: 15 INDIAFKPDGTQLILAAGSR---LLVYDTSD-GTLLQPLKGHKDTVYCVAYAKDGKRFAS 70
+ D+ F PDG+ LIL + SR L V+D D G +++ L+GH++ VY A++ D S
Sbjct: 173 VRDLTFAPDGS-LILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCS 231
Query: 71 GSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKAPKG------- 123
A K+V +W KYT + H V A D +P G
Sbjct: 232 VGASKAVFLWNMD-----KYTMIRKLEGHHHD-----------VVACDFSPDGALLATAS 275
Query: 124 ----------QGGRI-----DCLRPSVQNQPGQKHNDAIQCVSYNPITHQLASCSSSDF- 167
G I P G ++ ++ VS++ +AS +
Sbjct: 276 YDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMV 335
Query: 168 GLWSPEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGII 207
W ++ + S +CC+++ DG LA G +G +
Sbjct: 336 RFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSV 375
Score = 38.5 bits (88), Expect = 0.042
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
Query: 9 DKAEHCINDI--AFKPDGTQLILAAG---SRLLVYDTSDGTLLQPLKGHKDTVYCVAYAK 63
+K C+N F+ QL+LA G R+ ++D G LL L H + V + +A
Sbjct: 121 EKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAP 180
Query: 64 DGKR-FASGSADKSVIIWTSKLEG 86
DG S S DK++ +W K +G
Sbjct: 181 DGSLILVSASRDKTLRVWDLKDDG 204
>gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo
sapiens]
Length = 275
Score = 51.2 bits (121), Expect = 6e-06
Identities = 54/220 (24%), Positives = 88/220 (40%), Gaps = 44/220 (20%)
Query: 15 INDIAFKPDGTQLILAAGSR---LLVYDTSD-GTLLQPLKGHKDTVYCVAYAKDGKRFAS 70
+ D+ F PDG+ LIL + SR L V+D D G +++ L+GH++ VY A++ D S
Sbjct: 27 VRDLTFAPDGS-LILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCS 85
Query: 71 GSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKAPKG------- 123
A K+V +W KYT + H V A D +P G
Sbjct: 86 VGASKAVFLWNMD-----KYTMIRKLEGHHHD-----------VVACDFSPDGALLATAS 129
Query: 124 ----------QGGRI-----DCLRPSVQNQPGQKHNDAIQCVSYNPITHQLASCSSSDF- 167
G I P G ++ ++ VS++ +AS +
Sbjct: 130 YDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMV 189
Query: 168 GLWSPEQKSVSKHKSSSKIICCSWTNDGQYLALGMFNGII 207
W ++ + S +CC+++ DG LA G +G +
Sbjct: 190 RFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSV 229
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 50.4 bits (119), Expect = 1e-05
Identities = 73/288 (25%), Positives = 107/288 (37%), Gaps = 72/288 (25%)
Query: 13 HCI----NDIAFKPDGTQL-------ILAAGSRLLVYD------TSDGTLLQPLKGHKDT 55
HCI +D+ D T L +LA GS YD T DG L L HK
Sbjct: 225 HCIREGGHDVPSNKDVTSLDWNTNGTLLATGS----YDGFARIWTEDGNLASTLGQHKGP 280
Query: 56 VYCVAYAKDGKRFASGSADKSVIIW---TSKLEGILKYTS-------W-------SVMSS 98
++ + + + G S DK+ IIW T + + + S W S +
Sbjct: 281 IFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTD 340
Query: 99 LHLHLPFLGLHKTVR--------VTATDKAPKGQ---------GGRIDCLRPSVQNQPGQ 141
+ +H+ LG + V+ V A P G +I ++ V Q
Sbjct: 341 MCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQ 400
Query: 142 KHNDAIQCVSYNPI---------THQLASCS-SSDFGLWSPEQKSVSKH---KSSSKIIC 188
HN I + ++P LAS S S LW E + V H K +
Sbjct: 401 AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIE-RGVCTHTLTKHQEPVYS 459
Query: 189 CSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWN 236
+++ DG+YLA G F+ + I N V R G I+ +CWN
Sbjct: 460 VAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGG---IFEVCWN 504
Score = 47.4 bits (111), Expect = 9e-05
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 20/97 (20%)
Query: 7 WRDKAEHCIND----------IAFKPDG-------TQLILAAGS---RLLVYDTSDGTLL 46
W K E CI+D I + P G + ++LA+ S + ++D G
Sbjct: 388 WSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCT 447
Query: 47 QPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSK 83
L H++ VY VA++ DGK ASGS DK V IW ++
Sbjct: 448 HTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQ 484
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 50.4 bits (119), Expect = 1e-05
Identities = 73/288 (25%), Positives = 107/288 (37%), Gaps = 72/288 (25%)
Query: 13 HCI----NDIAFKPDGTQL-------ILAAGSRLLVYD------TSDGTLLQPLKGHKDT 55
HCI +D+ D T L +LA GS YD T DG L L HK
Sbjct: 225 HCIREGGHDVPSNKDVTSLDWNTNGTLLATGS----YDGFARIWTEDGNLASTLGQHKGP 280
Query: 56 VYCVAYAKDGKRFASGSADKSVIIW---TSKLEGILKYTS-------W-------SVMSS 98
++ + + + G S DK+ IIW T + + + S W S +
Sbjct: 281 IFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTD 340
Query: 99 LHLHLPFLGLHKTVR--------VTATDKAPKGQ---------GGRIDCLRPSVQNQPGQ 141
+ +H+ LG + V+ V A P G +I ++ V Q
Sbjct: 341 MCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQ 400
Query: 142 KHNDAIQCVSYNPI---------THQLASCS-SSDFGLWSPEQKSVSKH---KSSSKIIC 188
HN I + ++P LAS S S LW E + V H K +
Sbjct: 401 AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIE-RGVCTHTLTKHQEPVYS 459
Query: 189 CSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWN 236
+++ DG+YLA G F+ + I N V R G I+ +CWN
Sbjct: 460 VAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGG---IFEVCWN 504
Score = 47.4 bits (111), Expect = 9e-05
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 20/97 (20%)
Query: 7 WRDKAEHCIND----------IAFKPDG-------TQLILAAGS---RLLVYDTSDGTLL 46
W K E CI+D I + P G + ++LA+ S + ++D G
Sbjct: 388 WSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCT 447
Query: 47 QPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSK 83
L H++ VY VA++ DGK ASGS DK V IW ++
Sbjct: 448 HTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQ 484
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 50.4 bits (119), Expect = 1e-05
Identities = 73/288 (25%), Positives = 107/288 (37%), Gaps = 72/288 (25%)
Query: 13 HCI----NDIAFKPDGTQL-------ILAAGSRLLVYD------TSDGTLLQPLKGHKDT 55
HCI +D+ D T L +LA GS YD T DG L L HK
Sbjct: 276 HCIREGGHDVPSNKDVTSLDWNTNGTLLATGS----YDGFARIWTEDGNLASTLGQHKGP 331
Query: 56 VYCVAYAKDGKRFASGSADKSVIIW---TSKLEGILKYTS-------W-------SVMSS 98
++ + + + G S DK+ IIW T + + + S W S +
Sbjct: 332 IFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTD 391
Query: 99 LHLHLPFLGLHKTVR--------VTATDKAPKGQ---------GGRIDCLRPSVQNQPGQ 141
+ +H+ LG + V+ V A P G +I ++ V Q
Sbjct: 392 MCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQ 451
Query: 142 KHNDAIQCVSYNPI---------THQLASCS-SSDFGLWSPEQKSVSKH---KSSSKIIC 188
HN I + ++P LAS S S LW E + V H K +
Sbjct: 452 AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIE-RGVCTHTLTKHQEPVYS 510
Query: 189 CSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWN 236
+++ DG+YLA G F+ + I N V R G I+ +CWN
Sbjct: 511 VAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGG---IFEVCWN 555
Score = 47.4 bits (111), Expect = 9e-05
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 20/97 (20%)
Query: 7 WRDKAEHCIND----------IAFKPDG-------TQLILAAGS---RLLVYDTSDGTLL 46
W K E CI+D I + P G + ++LA+ S + ++D G
Sbjct: 439 WSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCT 498
Query: 47 QPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSK 83
L H++ VY VA++ DGK ASGS DK V IW ++
Sbjct: 499 HTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQ 535
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 50.4 bits (119), Expect = 1e-05
Identities = 73/288 (25%), Positives = 107/288 (37%), Gaps = 72/288 (25%)
Query: 13 HCI----NDIAFKPDGTQL-------ILAAGSRLLVYD------TSDGTLLQPLKGHKDT 55
HCI +D+ D T L +LA GS YD T DG L L HK
Sbjct: 276 HCIREGGHDVPSNKDVTSLDWNTNGTLLATGS----YDGFARIWTEDGNLASTLGQHKGP 331
Query: 56 VYCVAYAKDGKRFASGSADKSVIIW---TSKLEGILKYTS-------W-------SVMSS 98
++ + + + G S DK+ IIW T + + + S W S +
Sbjct: 332 IFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTD 391
Query: 99 LHLHLPFLGLHKTVR--------VTATDKAPKGQ---------GGRIDCLRPSVQNQPGQ 141
+ +H+ LG + V+ V A P G +I ++ V Q
Sbjct: 392 MCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQ 451
Query: 142 KHNDAIQCVSYNPI---------THQLASCS-SSDFGLWSPEQKSVSKH---KSSSKIIC 188
HN I + ++P LAS S S LW E + V H K +
Sbjct: 452 AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIE-RGVCTHTLTKHQEPVYS 510
Query: 189 CSWTNDGQYLALGMFNGIISIRNKNGEEKVKIERPGGSLSPIWSICWN 236
+++ DG+YLA G F+ + I N V R G I+ +CWN
Sbjct: 511 VAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGG---IFEVCWN 555
Score = 47.4 bits (111), Expect = 9e-05
Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 20/97 (20%)
Query: 7 WRDKAEHCIND----------IAFKPDG-------TQLILAAGS---RLLVYDTSDGTLL 46
W K E CI+D I + P G + ++LA+ S + ++D G
Sbjct: 439 WSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCT 498
Query: 47 QPLKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSK 83
L H++ VY VA++ DGK ASGS DK V IW ++
Sbjct: 499 HTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQ 535
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 49.7 bits (117), Expect = 2e-05
Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Query: 15 INDIAFKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
I+D+A+ D ++L+ A+ + L ++D G L+ LKGH + V+C + SGS
Sbjct: 86 ISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSF 145
Query: 74 DKSVIIWTSKLEGILKYTS 92
D++V IW K LK S
Sbjct: 146 DETVKIWEVKTGKCLKTLS 164
Score = 41.2 bits (95), Expect = 0.006
Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Query: 15 INDIAFKPDGTQLILAAGSRLLV-YDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSA 73
++ + F P+G L ++ RL++ + DG + L GH + VA++ D R S S
Sbjct: 44 VSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASD 103
Query: 74 DKSVIIWTSKLEGILK 89
DK++ +W + LK
Sbjct: 104 DKTLKLWDVRSGKCLK 119
Score = 40.8 bits (94), Expect = 0.008
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Query: 15 INDIAFKPDGTQLILAA-GSRLLVYDTSDGTLLQPLKGHKDTVYCV---AYAKDGKRFAS 70
++ + F P+G ++ A + L ++D S G L+ GHK+ YC+ GK S
Sbjct: 213 VSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVS 272
Query: 71 GSADKSVIIWTSKLEGILK 89
GS D V IW + + I++
Sbjct: 273 GSEDNLVYIWNLQTKEIVQ 291
Score = 34.7 bits (78), Expect = 0.61
Identities = 40/170 (23%), Positives = 76/170 (44%), Gaps = 22/170 (12%)
Query: 49 LKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGL 108
L GH + V V ++ +G+ AS SAD+ +IIW +G KY +L +
Sbjct: 37 LVGHTEAVSSVKFSPNGEWLASSSADRLIIIW-GAYDG--KYEKTLYGHNLEISDVAWSS 93
Query: 109 HKTVRVTATD----KAPKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSYNPITHQLASCSS 164
+ V+A+D K + G+ CL+ + H++ + C ++NP ++ + S S
Sbjct: 94 DSSRLVSASDDKTLKLWDVRSGK--CLKTL------KGHSNYVFCCNFNPPSNLIISGSF 145
Query: 165 SD-FGLWSPEQ----KSVSKHKSSSKIICCSWTNDGQYLALGMFNGIISI 209
+ +W + K++S H S + + G + G ++G+ I
Sbjct: 146 DETVKIWEVKTGKCLKTLSAH--SDPVSAVHFNCSGSLIVSGSYDGLCRI 193
>gi|32483359 apoptotic peptidase activating factor 1 isoform c [Homo
sapiens]
Length = 1248
Score = 48.5 bits (114), Expect = 4e-05
Identities = 53/210 (25%), Positives = 85/210 (40%), Gaps = 34/210 (16%)
Query: 20 FKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVI 78
F DG ++ + L V+ G L +K H+D V C A++ D + A+ S DK V
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVK 682
Query: 79 IWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKAPKGQGGRIDC-LRPSVQN 137
IW S + G L +T ++ H + T G DC L+ N
Sbjct: 683 IWNS-MTGELVHTYDEHSEQVNCCHFTNSSHHLLLAT----------GSSDCFLKLWDLN 731
Query: 138 QPGQK-----HNDAIQCVSYNPITHQLASCSS-SDFGLW----SPEQKSVS--------- 178
Q + H +++ ++P LASCS+ LW + E+KS++
Sbjct: 732 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE 791
Query: 179 --KHKSSSKIICCSWTNDGQYLALGMFNGI 206
+ + CCSW+ DG + + N I
Sbjct: 792 DPQEDMEVIVKCCSWSADGARIMVAAKNKI 821
Score = 33.5 bits (75), Expect = 1.4
Identities = 38/166 (22%), Positives = 68/166 (40%), Gaps = 12/166 (7%)
Query: 49 LKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGL 108
++ H D VY +++DG+R AS ADK++ ++ K E K L F
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVF--KAETGEKLLEIKAHEDEVLCCAFSTD 668
Query: 109 HKTVRVTATDKAPKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSY-NPITHQLASCSSSD- 166
+ + + DK K L + +H++ + C + N H L + SSD
Sbjct: 669 DRFIATCSVDKKVKIWNSMTGELVHTY-----DEHSEQVNCCHFTNSSHHLLLATGSSDC 723
Query: 167 -FGLWSPEQKSV--SKHKSSSKIICCSWTNDGQYLALGMFNGIISI 209
LW QK + ++ + C ++ D + LA +G + +
Sbjct: 724 FLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKL 769
Score = 32.0 bits (71), Expect = 3.9
Identities = 15/65 (23%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 20 FKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVI 78
F P ++A + +++T + + +GH V+ V ++ DG F + S D+++
Sbjct: 848 FSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIR 907
Query: 79 IWTSK 83
+W +K
Sbjct: 908 LWETK 912
>gi|7108333 apoptotic peptidase activating factor 1 isoform a [Homo
sapiens]
Length = 1237
Score = 48.5 bits (114), Expect = 4e-05
Identities = 53/210 (25%), Positives = 85/210 (40%), Gaps = 34/210 (16%)
Query: 20 FKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVI 78
F DG ++ + L V+ G L +K H+D V C A++ D + A+ S DK V
Sbjct: 612 FSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVK 671
Query: 79 IWTSKLEGILKYTSWSVMSSLHLHLPFLGLHKTVRVTATDKAPKGQGGRIDC-LRPSVQN 137
IW S + G L +T ++ H + T G DC L+ N
Sbjct: 672 IWNS-MTGELVHTYDEHSEQVNCCHFTNSSHHLLLAT----------GSSDCFLKLWDLN 720
Query: 138 QPGQK-----HNDAIQCVSYNPITHQLASCSS-SDFGLW----SPEQKSVS--------- 178
Q + H +++ ++P LASCS+ LW + E+KS++
Sbjct: 721 QKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLE 780
Query: 179 --KHKSSSKIICCSWTNDGQYLALGMFNGI 206
+ + CCSW+ DG + + N I
Sbjct: 781 DPQEDMEVIVKCCSWSADGARIMVAAKNKI 810
Score = 33.5 bits (75), Expect = 1.4
Identities = 38/166 (22%), Positives = 68/166 (40%), Gaps = 12/166 (7%)
Query: 49 LKGHKDTVYCVAYAKDGKRFASGSADKSVIIWTSKLEGILKYTSWSVMSSLHLHLPFLGL 108
++ H D VY +++DG+R AS ADK++ ++ K E K L F
Sbjct: 600 VRPHTDAVYHACFSEDGQRIASCGADKTLQVF--KAETGEKLLEIKAHEDEVLCCAFSTD 657
Query: 109 HKTVRVTATDKAPKGQGGRIDCLRPSVQNQPGQKHNDAIQCVSY-NPITHQLASCSSSD- 166
+ + + DK K L + +H++ + C + N H L + SSD
Sbjct: 658 DRFIATCSVDKKVKIWNSMTGELVHTY-----DEHSEQVNCCHFTNSSHHLLLATGSSDC 712
Query: 167 -FGLWSPEQKSV--SKHKSSSKIICCSWTNDGQYLALGMFNGIISI 209
LW QK + ++ + C ++ D + LA +G + +
Sbjct: 713 FLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKL 758
Score = 32.0 bits (71), Expect = 3.9
Identities = 15/65 (23%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 20 FKPDGTQLILAAGSRLL-VYDTSDGTLLQPLKGHKDTVYCVAYAKDGKRFASGSADKSVI 78
F P ++A + +++T + + +GH V+ V ++ DG F + S D+++
Sbjct: 837 FSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIR 896
Query: 79 IWTSK 83
+W +K
Sbjct: 897 LWETK 901
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,544,650
Number of Sequences: 37866
Number of extensions: 2294177
Number of successful extensions: 10725
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 104
Number of HSP's that attempted gapping in prelim test: 9490
Number of HSP's gapped (non-prelim): 1154
length of query: 1292
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1178
effective length of database: 13,930,794
effective search space: 16410475332
effective search space used: 16410475332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.