Guide to the Human Genome
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Search of human proteins with 164664518

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
         (483 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   963   0.0  
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   277   2e-74
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   276   2e-74
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   273   3e-73
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi...   245   7e-65
gi|4758112 HLA-B associated transcript 1 [Homo sapiens]               244   1e-64
gi|18375623 HLA-B associated transcript 1 [Homo sapiens]              244   1e-64
gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo sapi...   225   8e-59
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   215   8e-56
gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sap...   211   1e-54
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   205   8e-53
gi|8922886 DDX19-like protein [Homo sapiens]                          204   2e-52
gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H...   203   3e-52
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   196   3e-50
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   195   7e-50
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   195   7e-50
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   193   3e-49
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   193   3e-49
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   193   3e-49
gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [...   189   6e-48
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         185   9e-47
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          185   9e-47
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi...   185   9e-47
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   183   3e-46
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   183   3e-46
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   183   3e-46
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...   181   1e-45
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   181   1e-45
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi...   181   2e-45
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   180   2e-45

>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  963 bits (2489), Expect = 0.0
 Identities = 483/483 (100%), Positives = 483/483 (100%)

Query: 1   MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ 60
           MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ
Sbjct: 1   MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQ 60

Query: 61  SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS 120
           SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS
Sbjct: 61  SMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPS 120

Query: 121 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV 180
           PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV
Sbjct: 121 PIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQV 180

Query: 181 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV 240
           SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV
Sbjct: 181 SQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHV 240

Query: 241 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL 300
           QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL
Sbjct: 241 QMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL 300

Query: 301 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS 360
           MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS
Sbjct: 301 MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYS 360

Query: 361 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH 420
           CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH
Sbjct: 361 CFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLH 420

Query: 421 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED 480
           RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED
Sbjct: 421 RIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVED 480

Query: 481 EKP 483
           EKP
Sbjct: 481 EKP 483


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  277 bits (708), Expect = 2e-74
 Identities = 144/372 (38%), Positives = 232/372 (62%), Gaps = 4/372 (1%)

Query: 96  NEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL 155
           + F+D  L   LL GI+  G+EKPS IQ+ +I   + G D++A+A++GTGK+  + I +L
Sbjct: 32  DSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISIL 91

Query: 156 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLD-D 214
           ++++L     QA+V+ PTRELA Q+ ++ + +  +MG A   A  GGTN+R ++ +L  +
Sbjct: 92  QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMG-ASCHACIGGTNVRAEVQKLQME 150

Query: 215 TVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQIL 274
             H+++ TPGR+ D++ +      +++M VLDEAD++LS+ F   + DI   L  N Q++
Sbjct: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV 210

Query: 275 LYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVT-ERQKVHCLNTLFSRL 332
           L SAT P  V +     ++ P  I +  EELTL+G+ Q+Y  V  E  K+  L  L+  L
Sbjct: 211 LLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 270

Query: 333 QINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 392
            I Q++IF N+ ++V+ L +K+    ++   +H  M Q+ R+ +  +FR+G  R L+ TD
Sbjct: 271 TITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTD 330

Query: 393 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQ 452
           L  RGID+Q V++VIN+D P   E Y+HRIGR GRFG  G+AIN++T +D+  L+ IE  
Sbjct: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETF 390

Query: 453 LGTEIKPIPSNI 464
             T I+ +P N+
Sbjct: 391 YNTSIEEMPLNV 402


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  276 bits (707), Expect = 2e-74
 Identities = 143/378 (37%), Positives = 237/378 (62%), Gaps = 7/378 (1%)

Query: 89  DVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSG 148
           DVT T    F+   L+ +LL GI+  G+EKPS IQ+ +I   + GRD++A++++GTGK+ 
Sbjct: 35  DVTPT----FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTA 90

Query: 149 AYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDD 208
            + I +L+ LD++    QA+++ PTRELA+Q+ +  + +  +M   +  A  GGTN+ +D
Sbjct: 91  TFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMN-VQCHACIGGTNVGED 149

Query: 209 IMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLP 268
           I +LD   HVV  TPGR+ D+I++   +   ++M+VLDEAD++L++ F + + D+   LP
Sbjct: 150 IRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLP 209

Query: 269 KNRQILLYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVT-ERQKVHCLN 326
              Q++L SAT P  + +  N  +  P  I +  +ELTL+G+ Q++  V  E  K   L 
Sbjct: 210 PATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLC 269

Query: 327 TLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCR 386
            L+  L I Q++IFCN+ ++V+ L +K+ +  ++   +H  M Q+ R  +  +FR+G  R
Sbjct: 270 DLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASR 329

Query: 387 NLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNL 446
            L+ TD++ RG+D+  V+++IN+D P   E Y+HRIGRSGR+G  G+AIN +  DD   L
Sbjct: 330 VLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRIL 389

Query: 447 KSIEEQLGTEIKPIPSNI 464
           + IE+   T+I  +P N+
Sbjct: 390 RDIEQYYSTQIDEMPMNV 407


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  273 bits (698), Expect = 3e-73
 Identities = 143/372 (38%), Positives = 233/372 (62%), Gaps = 4/372 (1%)

Query: 96  NEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL 155
           + F+D  LK  LL GI+  G+EKPS IQ+ +I   + G D++A+A++GTGK+  + I +L
Sbjct: 33  DNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISIL 92

Query: 156 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLD-D 214
           ++L+++    QA+V+ PTRELA Q+ ++ + +  +MG A   A  GGTN+R+++ +L  +
Sbjct: 93  QQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMG-ATCHACIGGTNVRNEMQKLQAE 151

Query: 215 TVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQIL 274
             H+V+ TPGR+ D++ +       ++M VLDEAD++LS+ F   + +I   L  + Q++
Sbjct: 152 APHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVV 211

Query: 275 LYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVT-ERQKVHCLNTLFSRL 332
           L SAT P  V +     ++ P  I +  EELTL+G+ Q+Y  V  E  K+  L  L+  L
Sbjct: 212 LLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETL 271

Query: 333 QINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 392
            I Q++IF N+ ++V+ L +K+    ++   +H  M Q+ R+ +  +FR+G  R L+ TD
Sbjct: 272 TITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTD 331

Query: 393 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQ 452
           L  RGID+Q V++VIN+D P   E Y+HRIGR GRFG  G+AIN +T +D+  L+ IE  
Sbjct: 332 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETF 391

Query: 453 LGTEIKPIPSNI 464
             T ++ +P N+
Sbjct: 392 YNTTVEEMPMNV 403


>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
           sapiens]
          Length = 427

 Score =  245 bits (625), Expect = 7e-65
 Identities = 141/399 (35%), Positives = 227/399 (56%), Gaps = 8/399 (2%)

Query: 79  PPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILA 138
           P KD++       S   + F D+ LK ELL  I + G+E PS +Q E IP A+ G D+L 
Sbjct: 30  PKKDIK---GSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLC 86

Query: 139 RAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMA 198
           +AK+G GK+  +++  L++++     +  +V+  TRELA Q+S+   + SK+M   KV  
Sbjct: 87  QAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSV 146

Query: 199 TTGGTNLR-DDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DF 256
             GG +++ D+ +   +  HVV+ TPGRIL L++     + +V+  VLDE DK+L Q D 
Sbjct: 147 FFGGLSIKKDEEVLKKNCPHVVVGTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDM 206

Query: 257 VQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEE--LTLKGVTQYYA 314
            + +++I    P  +Q +++SAT    ++      +Q P E+ + +E  LTL G+ QYY 
Sbjct: 207 RRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYV 266

Query: 315 YVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRN 374
            + + +K   L  L   L+ NQ IIF  S QR   LA+ + +  +    IH  M QE R 
Sbjct: 267 KLKDSEKNRKLFDLLDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERL 326

Query: 375 RVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLA 434
             +  F++   R LV T+LF RG+DI+ VN+V N+D P+ ++TYLHR+ R+GRFG  GLA
Sbjct: 327 SRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLA 386

Query: 435 INLIT-YDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAE 472
           I  ++  +D   L  ++++    +  +P  ID S Y+ +
Sbjct: 387 ITFVSDENDAKILNDVQDRFEVNVAELPEEIDISTYIEQ 425


>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  244 bits (624), Expect = 1e-64
 Identities = 145/429 (33%), Positives = 234/429 (54%), Gaps = 11/429 (2%)

Query: 49  NTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELL 108
           N ++N           T   GD  +   K   KD++       S   + F D+ LK ELL
Sbjct: 4   NDVDNELLDYEDDEVETAAGGDGAEAPAK---KDVK---GSYVSIHSSGFRDFLLKPELL 57

Query: 109 MGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAM 168
             I + G+E PS +Q E IP A+ G D+L +AK+G GK+  +++  L++L+     +  +
Sbjct: 58  RAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVL 117

Query: 169 VIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLR-DDIMRLDDTVHVVIATPGRIL 227
           V+  TRELA Q+S+   + SK+M   KV    GG +++ D+ +   +  H+V+ TPGRIL
Sbjct: 118 VMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRIL 177

Query: 228 DLIKKGVAKVDHVQMIVLDEADKLLSQ-DFVQIMEDIILTLPKNRQILLYSATFPLSVQK 286
            L +     + H++  +LDE DK+L Q D  + +++I    P  +Q++++SAT    ++ 
Sbjct: 178 ALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRP 237

Query: 287 FMNSHLQKPYEINLMEE--LTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSS 344
                +Q P EI + +E  LTL G+ QYY  + + +K   L  L   L+ NQ +IF  S 
Sbjct: 238 VCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSV 297

Query: 345 QRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVN 404
           QR   LA+ + +  +    IH  M QE R   +  F++   R LV T+LF RG+DI+ VN
Sbjct: 298 QRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVN 357

Query: 405 VVINFDFPKLAETYLHRIGRSGRFGHLGLAINLIT-YDDRFNLKSIEEQLGTEIKPIPSN 463
           +  N+D P+ ++TYLHR+ R+GRFG  GLAI  ++  +D   L  ++++    I  +P  
Sbjct: 358 IAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDE 417

Query: 464 IDKSLYVAE 472
           ID S Y+ +
Sbjct: 418 IDISSYIEQ 426


>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  244 bits (624), Expect = 1e-64
 Identities = 145/429 (33%), Positives = 234/429 (54%), Gaps = 11/429 (2%)

Query: 49  NTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELL 108
           N ++N           T   GD  +   K   KD++       S   + F D+ LK ELL
Sbjct: 4   NDVDNELLDYEDDEVETAAGGDGAEAPAK---KDVK---GSYVSIHSSGFRDFLLKPELL 57

Query: 109 MGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAM 168
             I + G+E PS +Q E IP A+ G D+L +AK+G GK+  +++  L++L+     +  +
Sbjct: 58  RAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVL 117

Query: 169 VIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLR-DDIMRLDDTVHVVIATPGRIL 227
           V+  TRELA Q+S+   + SK+M   KV    GG +++ D+ +   +  H+V+ TPGRIL
Sbjct: 118 VMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRIL 177

Query: 228 DLIKKGVAKVDHVQMIVLDEADKLLSQ-DFVQIMEDIILTLPKNRQILLYSATFPLSVQK 286
            L +     + H++  +LDE DK+L Q D  + +++I    P  +Q++++SAT    ++ 
Sbjct: 178 ALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRP 237

Query: 287 FMNSHLQKPYEINLMEE--LTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSS 344
                +Q P EI + +E  LTL G+ QYY  + + +K   L  L   L+ NQ +IF  S 
Sbjct: 238 VCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSV 297

Query: 345 QRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVN 404
           QR   LA+ + +  +    IH  M QE R   +  F++   R LV T+LF RG+DI+ VN
Sbjct: 298 QRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVN 357

Query: 405 VVINFDFPKLAETYLHRIGRSGRFGHLGLAINLIT-YDDRFNLKSIEEQLGTEIKPIPSN 463
           +  N+D P+ ++TYLHR+ R+GRFG  GLAI  ++  +D   L  ++++    I  +P  
Sbjct: 358 IAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDE 417

Query: 464 IDKSLYVAE 472
           ID S Y+ +
Sbjct: 418 IDISSYIEQ 426


>gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo
           sapiens]
          Length = 824

 Score =  225 bits (573), Expect = 8e-59
 Identities = 134/396 (33%), Positives = 212/396 (53%), Gaps = 12/396 (3%)

Query: 84  RIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNG 143
           R +T DV   +  +FE   L R +L G+   G+E+PSP+Q ++IP+   G D++ +AK+G
Sbjct: 50  RTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSG 109

Query: 144 TGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGT 203
           TGK+  +    L+ L L+  + Q +++ PTRE+A+Q+  +   +   M G +     GGT
Sbjct: 110 TGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGT 169

Query: 204 NLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DFVQIMED 262
            L  D  RL    H+ + +PGRI  LI+        +++ +LDEADKLL +  F + +  
Sbjct: 170 PLSQDKTRLKKC-HIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINW 228

Query: 263 IILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL-MEELTLKGVTQYYAYVTE--- 318
           I  +LP ++Q+L  SAT+P  +   +  +++ P  + L   + +L G+ QYY  V     
Sbjct: 229 IYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPL 288

Query: 319 -----RQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHR 373
                 +K   L  LFSR+  NQ+++F N   R + LA  +S  G+    I   M Q  R
Sbjct: 289 AHKVFEEKTQHLQELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQR 348

Query: 374 NRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGL 433
                  ++  CR L+ TDL +RGID + VN+V+N D P   ETY+HRIGR+GRFG LGL
Sbjct: 349 LDAMAKLKHFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGL 408

Query: 434 AINLITYDDRFN-LKSIEEQLGTEIKPIPSNIDKSL 468
            +      +  N +  I ++    + P+P  I   L
Sbjct: 409 TVTYCCRGEEENMMMRIAQKCNINLLPLPDPIPSGL 444


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  215 bits (547), Expect = 8e-56
 Identities = 123/382 (32%), Positives = 214/382 (56%), Gaps = 5/382 (1%)

Query: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 157
           F+D  +   L     ++GW KP+ IQ E+IP+AL GRDI+  A+ G+GK+GA+ +P+L  
Sbjct: 26  FKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNA 85

Query: 158 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 217
           L      + A+V+ PTRELA Q+S+    +   +G  +     GG +     + L    H
Sbjct: 86  LLETPQRLFALVLTPTRELAFQISEQFEALGSSIG-VQSAVIVGGIDSMSQSLALAKKPH 144

Query: 218 VVIATPGRILDLIK--KGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILL 275
           ++IATPGR++D ++  KG   +  ++ +V+DEAD++L+ DF   ++ I+  +P++R+  L
Sbjct: 145 IIIATPGRLIDHLENTKGF-NLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFL 203

Query: 276 YSATFPLSVQKFMNSHLQKPYEINLMEEL-TLKGVTQYYAYVTERQKVHCLNTLFSRLQI 334
           +SAT    VQK   + L+ P +  +  +  T++ + QYY ++  + K   L  + + L  
Sbjct: 204 FSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG 263

Query: 335 NQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLF 394
           N  +IFC++    +  A  +  LG++   +H +M Q  R    + F+      L+ TD+ 
Sbjct: 264 NSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVA 323

Query: 395 TRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLG 454
           +RG+DI  V+VV+NFD P  ++ Y+HR+GR+ R G  G AI  +T  D    + IE  +G
Sbjct: 324 SRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIG 383

Query: 455 TEIKPIPSNIDKSLYVAEYHSE 476
            ++   P+  D+ + + E  +E
Sbjct: 384 KKLPGFPTQDDEVMMLTERVAE 405


>gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo
           sapiens]
          Length = 483

 Score =  211 bits (537), Expect = 1e-54
 Identities = 132/375 (35%), Positives = 210/375 (56%), Gaps = 15/375 (4%)

Query: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSG--RDILARAKNGTGKSGAYLIPLL 155
           FE+  LK ELL GI+ MG+ +PS IQE ++P+ L+   ++++A++++GTGK+ A+++ +L
Sbjct: 99  FEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAML 158

Query: 156 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDT 215
            R++  +   Q + + PT ELALQ  ++  Q+ K     +VM    G  +       D T
Sbjct: 159 SRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGT---DIT 215

Query: 216 VHVVIATPGRILD-LIKKGVAKVDHVQMIVLDEADKLL-SQDFVQIMEDIILTLPKNRQI 273
             ++I TPG +LD   K  +  +  +++ VLDEAD ++ +Q F      I   LP   Q+
Sbjct: 216 KQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQM 275

Query: 274 LLYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVTERQ-KVHCLNTLFSR 331
           LL+SATF  SV  F    +  P  I L  EELTL  + QYY     R+ K   L  ++  
Sbjct: 276 LLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGS 335

Query: 332 LQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCT 391
           + I Q+IIFC + +  + L  ++ Q G+    +  ++  E R  +   FR+G  + L+ T
Sbjct: 336 ITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITT 395

Query: 392 DLFTRGIDIQAVNVVINFDFPKLA------ETYLHRIGRSGRFGHLGLAINLITYDDRFN 445
           ++  RGID++ V +V+NFD P         ETYLHRIGR+GRFG  GLA N+I  D+  +
Sbjct: 396 NVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPS 455

Query: 446 LKSIEEQLGTEIKPI 460
           L  I++   + IK +
Sbjct: 456 LMKIQDHFNSSIKQL 470


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  205 bits (521), Expect = 8e-53
 Identities = 117/374 (31%), Positives = 206/374 (55%), Gaps = 11/374 (2%)

Query: 103 LKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKK 162
           +  ++L  + + G+EKP+PIQ ++IP  +SGRD++  AK G+GK+ A+L+P+   +  ++
Sbjct: 379 ISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQR 438

Query: 163 DNIQ-----AMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 217
              +     A+++ PTRELALQ+++ C + SK +G  +V+   GGT + + I  L     
Sbjct: 439 SLEEGEGPIAVIMTPTRELALQITKECKKFSKTLG-LRVVCVYGGTGISEQIAELKRGAE 497

Query: 218 VVIATPGRILDLIKKGVAKVDH---VQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQIL 274
           +++ TPGR++D++     +V +   V  +VLDEAD++    F   +  I+  +  +RQ +
Sbjct: 498 IIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTV 557

Query: 275 LYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVTERQKVHCLNTLFSRLQ 333
           ++SATFP +++      L KP E+ +    +    V Q    + E +K   L  L    Q
Sbjct: 558 MFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQ 617

Query: 334 INQS-IIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 392
            + S IIF +  +  + L K + +  Y C  +H  + Q  R+ + +DF+NG C+ LV T 
Sbjct: 618 ESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATS 677

Query: 393 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQ 452
           +  RG+D++ + +V+N+  P   E Y+HR GR+GR G+ G A   IT D       I + 
Sbjct: 678 VAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKA 737

Query: 453 LGTEIKPIPSNIDK 466
           L      +P +++K
Sbjct: 738 LELSGTAVPPDLEK 751


>gi|8922886 DDX19-like protein [Homo sapiens]
          Length = 478

 Score =  204 bits (518), Expect = 2e-52
 Identities = 135/380 (35%), Positives = 215/380 (56%), Gaps = 18/380 (4%)

Query: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSG--RDILARAKNGTGKSGAYLIPLL 155
           FE+  LK +LL G++ MG+ +PS IQE ++P+ L+   ++++A++++GTGK+ A+++ +L
Sbjct: 93  FEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAML 152

Query: 156 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDT 215
            R++      Q + + PT ELALQ  ++  Q+ K     K+     G  L     ++ + 
Sbjct: 153 SRVEPSDRYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG-QKISE- 210

Query: 216 VHVVIATPGRILDLIKKGVAKVD--HVQMIVLDEADKLLSQDFVQIME-DIILTLPKNRQ 272
             +VI TPG +LD   K +  +D   +++ VLDEAD +++    Q     I   LP+N Q
Sbjct: 211 -QIVIGTPGTVLDWCSK-LKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQ 268

Query: 273 ILLYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVTER-QKVHCLNTLFS 330
           +LL+SATF  SV KF    +  P  I L  EE TL  + QYY   + R +K   L  L+ 
Sbjct: 269 MLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYG 328

Query: 331 RLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVC 390
            + I Q++IFC++ +    LA ++S+ G+    +  +M  E R  V   FR G  + LV 
Sbjct: 329 AITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVT 388

Query: 391 TDLFTRGIDIQAVNVVINFDFP------KLAETYLHRIGRSGRFGHLGLAINLITYDDRF 444
           T++  RGID++ V+VVINFD P         ETYLHRIGR+GRFG  GLA+N++      
Sbjct: 389 TNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSM 448

Query: 445 N-LKSIEEQLGTEIKPIPSN 463
           N L  I+E    +I+ + ++
Sbjct: 449 NILNRIQEHFNKKIERLDTD 468


>gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo
           sapiens]
          Length = 479

 Score =  203 bits (516), Expect = 3e-52
 Identities = 134/380 (35%), Positives = 215/380 (56%), Gaps = 18/380 (4%)

Query: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSG--RDILARAKNGTGKSGAYLIPLL 155
           FE+  LK +LL G++ MG+ +PS IQE ++P+ L+   ++++A++++GTGK+ A+++ +L
Sbjct: 94  FEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAML 153

Query: 156 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDT 215
            +++      Q + + PT ELALQ  ++  Q+ K     K+     G  L     ++ + 
Sbjct: 154 SQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG-QKISE- 211

Query: 216 VHVVIATPGRILDLIKKGVAKVD--HVQMIVLDEADKLLSQDFVQIME-DIILTLPKNRQ 272
             +VI TPG +LD   K +  +D   +++ VLDEAD +++    Q     I   LP+N Q
Sbjct: 212 -QIVIGTPGTVLDWCSK-LKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQ 269

Query: 273 ILLYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVTER-QKVHCLNTLFS 330
           +LL+SATF  SV KF    +  P  I L  EE TL  + QYY   + R +K   L  L+ 
Sbjct: 270 MLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYG 329

Query: 331 RLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVC 390
            + I Q++IFC++ +    LA ++S+ G+    +  +M  E R  V   FR G  + LV 
Sbjct: 330 AITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVT 389

Query: 391 TDLFTRGIDIQAVNVVINFDFP------KLAETYLHRIGRSGRFGHLGLAINLITYDDRF 444
           T++  RGID++ V+VVINFD P         ETYLHRIGR+GRFG  GLA+N++      
Sbjct: 390 TNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSM 449

Query: 445 N-LKSIEEQLGTEIKPIPSN 463
           N L  I+E    +I+ + ++
Sbjct: 450 NILNRIQEHFNKKIERLDTD 469


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  196 bits (499), Expect = 3e-50
 Identities = 121/381 (31%), Positives = 201/381 (52%), Gaps = 8/381 (2%)

Query: 97  EFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLE 156
           +FE   L   L   + + G+E P+PIQ + IP+ L GRDILA A  G+GK+ A+L+P++ 
Sbjct: 204 DFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIM 263

Query: 157 RLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTV 216
           R   +     A+++ PTRELA+Q+ +   ++   +   K +   GG  L   + RL   V
Sbjct: 264 RALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHV 323

Query: 217 HVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLY 276
            V+IATPGR+LD+IK+   ++  V+++V+DEAD +L   F Q + DI+  +P + Q +L 
Sbjct: 324 KVIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILV 383

Query: 277 SATFPLSVQKFMNSHLQKPYEINLMEE-LTLKGVTQYYAYVTERQKVHCLNTLFSRLQIN 335
           SAT P S+++  +  L  P  I   E+ L    V Q   +V +  K   L  + +  ++ 
Sbjct: 384 SATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLF 443

Query: 336 QS--IIFCNSSQRVELLAKKISQL-GYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 392
           +   ++F +     +LL++ + ++ G     IH++  Q  R  +      G    +V T 
Sbjct: 444 KPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTG 503

Query: 393 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQ 452
           +  RG+D+ +V +V+NFD P   + Y+H+IGR GR G  G AI  I      N K +   
Sbjct: 504 VLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINN----NSKRLFWD 559

Query: 453 LGTEIKPIPSNIDKSLYVAEY 473
           +   +KP  S +   L  + Y
Sbjct: 560 IAKRVKPTGSILPPQLLNSPY 580


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  195 bits (496), Expect = 7e-50
 Identities = 129/414 (31%), Positives = 216/414 (52%), Gaps = 45/414 (10%)

Query: 73  KKTLKLPPKDLRIKTSDVT-STKGNE-------FEDYCLKRELLMGIFEMGWEKPSPIQE 124
           KK  ++  +D RI   D + +TKG +       ++D  L   +L  I + G+++P+PIQ 
Sbjct: 360 KKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQR 419

Query: 125 ESIPIALSGRDILARAKNGTGKSGAYLIPLL---------ERLDLKKDNIQAMVIVPTRE 175
           ++IPI L  RDI+  A+ G+GK+ A+LIPLL         +R++       A+++ PTRE
Sbjct: 420 QAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRE 479

Query: 176 LALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVA 235
           LA Q+ +  I+  K +G  + +A  GG +  D   RL     +VIATPGR++D+++    
Sbjct: 480 LAQQIEEETIKFGKPLG-IRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYL 538

Query: 236 KVDHVQMIVLDEADKLLSQDFVQIMEDIILTLP--------------------------K 269
            +     +VLDEAD+++   F   ++ I+  +P                          K
Sbjct: 539 VLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHK 598

Query: 270 NRQILLYSATFPLSVQKFMNSHLQKPYEINLMEE-LTLKGVTQYYAYVTERQKVHCLNTL 328
            RQ ++++AT P +V++   S+L++P  + +       + V Q    ++E +K   L  +
Sbjct: 599 YRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAI 658

Query: 329 FSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNL 388
             +      IIF N  +  ++LAK + ++GY+   +H    QE R     + + G    L
Sbjct: 659 LEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDIL 718

Query: 389 VCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDD 442
           V TD+  RGIDIQ V++V+N+D  K  E Y+HRIGR+GR G  G+AI  +T +D
Sbjct: 719 VATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKED 772


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  195 bits (496), Expect = 7e-50
 Identities = 118/355 (33%), Positives = 196/355 (55%), Gaps = 10/355 (2%)

Query: 113 EMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVP 172
           ++G ++P+P+Q   IP  L GRD L  AK G+GK+ A+++P+L++L      I  +V+ P
Sbjct: 19  QLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPYGIFCLVLTP 78

Query: 173 TRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKK 232
           TRELA Q+++    + K +G  K     GG ++    + L    HVVIATPGR+ D ++ 
Sbjct: 79  TRELAYQIAEQFRVLGKPLG-LKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRS 137

Query: 233 G-VAKVDHVQMIVLDEADKLLSQ---DFVQIMEDIILTLPKNRQILLYSATFPLSVQKFM 288
                +  ++ +V+DEAD+LL Q   DF   +E I+  +P  RQ LL+SAT   ++++  
Sbjct: 138 SNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLLFSATLTDTLRELQ 197

Query: 289 NSHLQKPYEINLMEEL-TLKGVTQYYAYVTERQKVHCLNTLFSRLQINQS----IIFCNS 343
                +P+       + T++ + Q Y  V E+ K   L  L  R Q        IIF N+
Sbjct: 198 GLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNT 257

Query: 344 SQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAV 403
            +  ++L   + +  +    +H+ M+Q+ R      F++ + R L+ TD+ +RG+DI  V
Sbjct: 258 CKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTV 317

Query: 404 NVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIK 458
            VVIN + P L + Y+HR+GR+ R G  G AI L+T  D   + +IEEQ+  +++
Sbjct: 318 QVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAIEEQIKKKLE 372


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  193 bits (491), Expect = 3e-49
 Identities = 122/361 (33%), Positives = 193/361 (53%), Gaps = 14/361 (3%)

Query: 91  TSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAY 150
           T T  + F+ Y    E++  I + G++KP+PIQ ++ PI L G D++  A+ GTGK+  Y
Sbjct: 240 TCTFDDAFQCY---PEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCY 296

Query: 151 LIP------LLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTN 204
           L+P      L   L  +++    +V+ PTRELALQV   C + S    G + +   GG N
Sbjct: 297 LMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYK--GLRSVCVYGGGN 354

Query: 205 LRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDII 264
             + I  L   V ++IATPGR+ DL       + ++  +VLDEADK+L   F   +  I+
Sbjct: 355 RDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKIL 414

Query: 265 LTLPKNRQILLYSATFPLSVQKFMNSHLQKPY--EINLMEELTLKGVTQYYAYVTERQK- 321
           L +  +RQ ++ SAT+P SV +   S+L++P    +  ++ + +  V Q     TE +K 
Sbjct: 415 LDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKW 474

Query: 322 VHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFR 381
            H    L S    ++ I+F +     + L+  +     S   +H    Q  R +   +F+
Sbjct: 475 SHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFK 534

Query: 382 NGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYD 441
            G  R L+ TDL +RG+D+  V  V NFDFP+  E Y+HRIGR+GR G  G++I  +T +
Sbjct: 535 TGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRN 594

Query: 442 D 442
           D
Sbjct: 595 D 595


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  193 bits (490), Expect = 3e-49
 Identities = 112/363 (30%), Positives = 191/363 (52%), Gaps = 6/363 (1%)

Query: 85  IKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGT 144
           ++  +    K   F+   L   +  GI + G++ P+PIQ ++IP+ L G+D++A A+ G+
Sbjct: 85  VRAQNKKKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGS 144

Query: 145 GKSGAYLIPLLERLDLK--KDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGG 202
           GK+  +L+P+ ERL     +   +A+++ PTRELALQ  +   ++ K  G  K     GG
Sbjct: 145 GKTACFLLPMFERLKTHSAQTGARALILSPTRELALQTLKFTKELGKFTG-LKTALILGG 203

Query: 203 TNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMED 262
             + D    L +   ++IATPGR++ +  +   K+  V+ +V DEAD+L    F + +++
Sbjct: 204 DRMEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQE 263

Query: 263 IILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTL-KGVTQYYAYVTERQK 321
           II  LP   Q +L+SAT P  + +F  + L +P  I L  +  L + +   +  V E  K
Sbjct: 264 IIARLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTK 323

Query: 322 VHCLNTLFSRL--QINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHD 379
              L  L   +    +Q+++F  +    E L + ++    SC +I++ +    R      
Sbjct: 324 AAVLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAK 383

Query: 380 FRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLIT 439
           F  G C  L+ TDL  RG+DI  ++ VIN+ FP   + +LHR+GR  R G  G A +L+ 
Sbjct: 384 FTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVA 443

Query: 440 YDD 442
            D+
Sbjct: 444 PDE 446


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  193 bits (490), Expect = 3e-49
 Identities = 112/363 (30%), Positives = 191/363 (52%), Gaps = 6/363 (1%)

Query: 85  IKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGT 144
           ++  +    K   F+   L   +  GI + G++ P+PIQ ++IP+ L G+D++A A+ G+
Sbjct: 85  VRAQNKKKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGS 144

Query: 145 GKSGAYLIPLLERLDLK--KDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGG 202
           GK+  +L+P+ ERL     +   +A+++ PTRELALQ  +   ++ K  G  K     GG
Sbjct: 145 GKTACFLLPMFERLKTHSAQTGARALILSPTRELALQTLKFTKELGKFTG-LKTALILGG 203

Query: 203 TNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMED 262
             + D    L +   ++IATPGR++ +  +   K+  V+ +V DEAD+L    F + +++
Sbjct: 204 DRMEDQFAALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQE 263

Query: 263 IILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTL-KGVTQYYAYVTERQK 321
           II  LP   Q +L+SAT P  + +F  + L +P  I L  +  L + +   +  V E  K
Sbjct: 264 IIARLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTK 323

Query: 322 VHCLNTLFSRL--QINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHD 379
              L  L   +    +Q+++F  +    E L + ++    SC +I++ +    R      
Sbjct: 324 AAVLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAK 383

Query: 380 FRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLIT 439
           F  G C  L+ TDL  RG+DI  ++ VIN+ FP   + +LHR+GR  R G  G A +L+ 
Sbjct: 384 FTLGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVA 443

Query: 440 YDD 442
            D+
Sbjct: 444 PDE 446


>gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3
           [Homo sapiens]
          Length = 370

 Score =  189 bits (479), Expect = 6e-48
 Identities = 127/364 (34%), Positives = 204/364 (56%), Gaps = 18/364 (4%)

Query: 114 MGWEKPSPIQEESIPIALSG--RDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIV 171
           MG+ +PS IQE ++P+ L+   ++++A++++GTGK+ A+++ +L +++      Q + + 
Sbjct: 1   MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60

Query: 172 PTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIK 231
           PT ELALQ  ++  Q+ K     K+     G  L     ++ +   +VI TPG +LD   
Sbjct: 61  PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERG-QKISE--QIVIGTPGTVLDWCS 117

Query: 232 KGVAKVD--HVQMIVLDEADKLLSQDFVQIME-DIILTLPKNRQILLYSATFPLSVQKFM 288
           K +  +D   +++ VLDEAD +++    Q     I   LP+N Q+LL+SATF  SV KF 
Sbjct: 118 K-LKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFA 176

Query: 289 NSHLQKPYEINLM-EELTLKGVTQYYAYVTER-QKVHCLNTLFSRLQINQSIIFCNSSQR 346
              +  P  I L  EE TL  + QYY   + R +K   L  L+  + I Q++IFC++ + 
Sbjct: 177 QKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKT 236

Query: 347 VELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVV 406
              LA ++S+ G+    +  +M  E R  V   FR G  + LV T++  RGID++ V+VV
Sbjct: 237 ASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVV 296

Query: 407 INFDFP------KLAETYLHRIGRSGRFGHLGLAINLITYDDRFN-LKSIEEQLGTEIKP 459
           INFD P         ETYLHRIGR+GRFG  GLA+N++      N L  I+E    +I+ 
Sbjct: 297 INFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIER 356

Query: 460 IPSN 463
           + ++
Sbjct: 357 LDTD 360


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  185 bits (469), Expect = 9e-47
 Identities = 118/381 (30%), Positives = 197/381 (51%), Gaps = 14/381 (3%)

Query: 81  KDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARA 140
           K++ ++  DV       F      + ++  + +  + +P+PIQ +  P+ALSGRD++  A
Sbjct: 156 KEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIA 215

Query: 141 KNGTGKSGAYLIPLLERLDLKK-----DNIQAMVIVPTRELALQVSQICIQVSKHMGGAK 195
           + G+GK+ AYL+P +  ++ +      D    +V+ PTRELA QV Q+     K     K
Sbjct: 216 QTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK-CSRLK 274

Query: 196 VMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQD 255
                GG      I  L+  V + IATPGR++D ++ G   +     +VLDEAD++L   
Sbjct: 275 STCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMG 334

Query: 256 FVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL--MEELTLKGVTQYY 313
           F   +  I+  +  +RQ L++SAT+P  V++     L+   +IN+  +E      + Q  
Sbjct: 335 FEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIV 394

Query: 314 AYVTERQKVHCLNTLFSRLQI---NQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQ 370
               E +K H L  L   +     N++IIF  + +R + L +++ + G+    IH    Q
Sbjct: 395 DVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQ 454

Query: 371 EHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGH 430
             R+ V ++FR+G    L+ TD+ +RG+D++ V  VIN+D+P  +E Y+HRIGR+ R  +
Sbjct: 455 PERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTN 514

Query: 431 LGLAINLITYDDRFNLKSIEE 451
            G A    T     NLK   E
Sbjct: 515 KGTAYTFFTPG---NLKQARE 532


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  185 bits (469), Expect = 9e-47
 Identities = 118/381 (30%), Positives = 197/381 (51%), Gaps = 14/381 (3%)

Query: 81  KDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARA 140
           K++ ++  DV       F      + ++  + +  + +P+PIQ +  P+ALSGRD++  A
Sbjct: 156 KEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIA 215

Query: 141 KNGTGKSGAYLIPLLERLDLKK-----DNIQAMVIVPTRELALQVSQICIQVSKHMGGAK 195
           + G+GK+ AYL+P +  ++ +      D    +V+ PTRELA QV Q+     K     K
Sbjct: 216 QTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK-CSRLK 274

Query: 196 VMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQD 255
                GG      I  L+  V + IATPGR++D ++ G   +     +VLDEAD++L   
Sbjct: 275 STCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMG 334

Query: 256 FVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINL--MEELTLKGVTQYY 313
           F   +  I+  +  +RQ L++SAT+P  V++     L+   +IN+  +E      + Q  
Sbjct: 335 FEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIV 394

Query: 314 AYVTERQKVHCLNTLFSRLQI---NQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQ 370
               E +K H L  L   +     N++IIF  + +R + L +++ + G+    IH    Q
Sbjct: 395 DVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQ 454

Query: 371 EHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGH 430
             R+ V ++FR+G    L+ TD+ +RG+D++ V  VIN+D+P  +E Y+HRIGR+ R  +
Sbjct: 455 PERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTN 514

Query: 431 LGLAINLITYDDRFNLKSIEE 451
            G A    T     NLK   E
Sbjct: 515 KGTAYTFFTPG---NLKQARE 532


>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
           sapiens]
          Length = 875

 Score =  185 bits (469), Expect = 9e-47
 Identities = 132/456 (28%), Positives = 234/456 (51%), Gaps = 19/456 (4%)

Query: 26  KPTGGPGGGGTQTQ-QQMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLR 84
           K    PG G      +  N+ K  ++     ++Q +      +   + +   +L     +
Sbjct: 3   KTANSPGSGARPDPVRSFNRWKKKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNYEK 62

Query: 85  IKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGT 144
           I  +++T      F D+ L ++ L G+ E  +   + IQ+++I +AL G+D+L  AK G+
Sbjct: 63  INVNEIT-----RFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGS 117

Query: 145 GKSGAYLIPLLERLD----LKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATT 200
           GK+ A+L+P+LE L        D +  ++I PTRELA Q  ++  +V K+   +  +   
Sbjct: 118 GKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLII- 176

Query: 201 GGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVA-KVDHVQMIVLDEADKLLSQDFVQI 259
           GG +L+ +  R+++ +++++ TPGR+L  + + V+     +QM+VLDEAD++L   F   
Sbjct: 177 GGKDLKHEAERINN-INILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADT 235

Query: 260 MEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEEL---TLKGVTQYYAYV 316
           M  +I  LPK RQ LL+SAT   SV+      L+ P  + + E+    T   + Q Y   
Sbjct: 236 MNAVIENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVC 295

Query: 317 TERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQL--GYSCFYIHAKMRQEHRN 374
             +QK+  L +        +SI+F +S + V+ L +   +L  G S   +H + +Q  R 
Sbjct: 296 ELQQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRM 355

Query: 375 RVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLA 434
            V+++F       L  TD+  RG+D  AVN V+ FD P+ A TY+HR GR+ R+   G A
Sbjct: 356 EVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEA 415

Query: 435 INLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYV 470
           + ++   ++  ++ +  Q    +K I  N +K + V
Sbjct: 416 LLILLPSEKAMVQQL-LQKKVPVKEIKINPEKLIDV 450


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  183 bits (465), Expect = 3e-46
 Identities = 119/358 (33%), Positives = 191/358 (53%), Gaps = 24/358 (6%)

Query: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 157
           FE+  L + L   I + G+ K +P+Q+ SIPI L+GRD++A A+ G+GK+ A+L+P+L  
Sbjct: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAH 349

Query: 158 LDLKKDNIQA-----------MVIVPTRELALQVSQICIQVSKHMGGAKVMATT--GGTN 204
           +    D I A           +++ PTREL   V+QI ++  K   G  V A    GGT 
Sbjct: 350 M--MHDGITASRFKELQEPECIIVAPTREL---VNQIYLEARKFSFGTCVRAVVIYGGTQ 404

Query: 205 LRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDII 264
           L   I ++    +++ ATPGR++D+I K    +  ++ +VLDEAD++L   F   M+ +I
Sbjct: 405 LGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 464

Query: 265 ----LTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEEL--TLKGVTQYYAYVTE 318
               +   + RQ L++SATFP  +Q+     L+  Y    + ++    + V Q    V +
Sbjct: 465 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQ 524

Query: 319 RQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFH 378
             K   L  +   +   ++++F  + ++ + +A  + Q   S   IH    Q  R +   
Sbjct: 525 FSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALG 584

Query: 379 DFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAIN 436
           DFR G C  LV T +  RG+DI+ V  VINFD P   + Y+HRIGR+GR G+ G AI+
Sbjct: 585 DFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  183 bits (465), Expect = 3e-46
 Identities = 119/358 (33%), Positives = 191/358 (53%), Gaps = 24/358 (6%)

Query: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 157
           FE+  L + L   I + G+ K +P+Q+ SIPI L+GRD++A A+ G+GK+ A+L+P+L  
Sbjct: 290 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAH 349

Query: 158 LDLKKDNIQA-----------MVIVPTRELALQVSQICIQVSKHMGGAKVMATT--GGTN 204
           +    D I A           +++ PTREL   V+QI ++  K   G  V A    GGT 
Sbjct: 350 M--MHDGITASRFKELQEPECIIVAPTREL---VNQIYLEARKFSFGTCVRAVVIYGGTQ 404

Query: 205 LRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDII 264
           L   I ++    +++ ATPGR++D+I K    +  ++ +VLDEAD++L   F   M+ +I
Sbjct: 405 LGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 464

Query: 265 ----LTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEEL--TLKGVTQYYAYVTE 318
               +   + RQ L++SATFP  +Q+     L+  Y    + ++    + V Q    V +
Sbjct: 465 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQ 524

Query: 319 RQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFH 378
             K   L  +   +   ++++F  + ++ + +A  + Q   S   IH    Q  R +   
Sbjct: 525 FSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALG 584

Query: 379 DFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAIN 436
           DFR G C  LV T +  RG+DI+ V  VINFD P   + Y+HRIGR+GR G+ G AI+
Sbjct: 585 DFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  183 bits (465), Expect = 3e-46
 Identities = 119/358 (33%), Positives = 191/358 (53%), Gaps = 24/358 (6%)

Query: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 157
           FE+  L + L   I + G+ K +P+Q+ SIPI L+GRD++A A+ G+GK+ A+L+P+L  
Sbjct: 256 FEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAH 315

Query: 158 LDLKKDNIQA-----------MVIVPTRELALQVSQICIQVSKHMGGAKVMATT--GGTN 204
           +    D I A           +++ PTREL   V+QI ++  K   G  V A    GGT 
Sbjct: 316 M--MHDGITASRFKELQEPECIIVAPTREL---VNQIYLEARKFSFGTCVRAVVIYGGTQ 370

Query: 205 LRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDII 264
           L   I ++    +++ ATPGR++D+I K    +  ++ +VLDEAD++L   F   M+ +I
Sbjct: 371 LGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLI 430

Query: 265 ----LTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEEL--TLKGVTQYYAYVTE 318
               +   + RQ L++SATFP  +Q+     L+  Y    + ++    + V Q    V +
Sbjct: 431 SCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVGQ 490

Query: 319 RQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFH 378
             K   L  +   +   ++++F  + ++ + +A  + Q   S   IH    Q  R +   
Sbjct: 491 FSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALG 550

Query: 379 DFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAIN 436
           DFR G C  LV T +  RG+DI+ V  VINFD P   + Y+HRIGR+GR G+ G AI+
Sbjct: 551 DFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 608


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score =  181 bits (459), Expect = 1e-45
 Identities = 111/346 (32%), Positives = 182/346 (52%), Gaps = 11/346 (3%)

Query: 106 ELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLK---- 161
           +LL  I  +G  KP+PIQ ++ PI L G D++  A+ GTGK+ +YL+P    LD +    
Sbjct: 232 DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISR 291

Query: 162 --KDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVV 219
             ++    +V+ PTRELAL V   C + S    G K +   GG N    I  +   V ++
Sbjct: 292 EQRNGPGMLVLTPTRELALHVEAECSKYSYK--GLKSICIYGGRNRNGQIEDISKGVDII 349

Query: 220 IATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSAT 279
           IATPGR+ DL       +  +  +V+DEADK+L  +F   +  I+L +  +RQ ++ SAT
Sbjct: 350 IATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSAT 409

Query: 280 FPLSVQKFMNSHLQKPYEINL--MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQS 337
           +P +V++   S+L+ P  + +  +  + +  V Q     TE++K          +  N  
Sbjct: 410 WPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDK 469

Query: 338 IIFCNSSQRV-ELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTR 396
           +I   S + + + L+   +  G S   +H    Q  + R   DF++G  + L+ TD+ +R
Sbjct: 470 VIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSR 529

Query: 397 GIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDD 442
           G+D+  V  V N+DFP+  + Y+HR+G  GR G  G ++ LIT  D
Sbjct: 530 GLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRD 575


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  181 bits (459), Expect = 1e-45
 Identities = 121/393 (30%), Positives = 204/393 (51%), Gaps = 26/393 (6%)

Query: 106 ELLMGIFEMG-WEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL--------- 155
           E++MG  E+  + +P+P+Q+ +IPI    RD++A A+ G+GK+ A+L+P+L         
Sbjct: 189 EIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPG 248

Query: 156 ERLDLKKDNIQ---------AMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLR 206
           E L   K+N +         ++V+ PTRELA+Q+ +   + S +    +     GG ++ 
Sbjct: 249 EALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFS-YRSRVRPCVVYGGADIG 307

Query: 207 DDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIIL- 265
             I  L+   H+++ATPGR++D++++G   +D  + +VLDEAD++L   F   +  I+  
Sbjct: 308 QQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQ 367

Query: 266 -TLPKN--RQILLYSATFPLSVQKFMNSHLQKPYEINLMEE-LTLKGVTQYYAYVTERQK 321
            T+P    R  +++SATFP  +Q      L +   + +     T + +TQ   +V E  K
Sbjct: 368 DTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDK 427

Query: 322 VHCLNTLFSRL-QINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDF 380
              L  L +   + + +++F  + +  + L   +   GY+C  IH    Q  R    H F
Sbjct: 428 RSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQF 487

Query: 381 RNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITY 440
           R+G    LV T +  RG+DI  V  VINFD P   E Y+HRIGR+GR G+LGLA +    
Sbjct: 488 RSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNE 547

Query: 441 DDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEY 473
            +    K + + L    + +PS ++   Y   Y
Sbjct: 548 RNINITKDLLDLLVEAKQEVPSWLENMAYEHHY 580


>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
           sapiens]
          Length = 600

 Score =  181 bits (458), Expect = 2e-45
 Identities = 113/355 (31%), Positives = 188/355 (52%), Gaps = 23/355 (6%)

Query: 103 LKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERL---- 158
           L  ++L  + E+G+   +P+Q  +IP+ +  +D+ A A  G+GK+ A++IP+LE L    
Sbjct: 16  LHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRRE 75

Query: 159 -DLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTV- 216
             LKK  + A++I PTRELA+Q+ ++    +KH      +   GG N  +D+ R      
Sbjct: 76  EKLKKSQVGAIIITPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPGEDVERFKQQGG 135

Query: 217 HVVIATPGRILDLIKKGVAKVD------HVQMIVLDEADKLLSQDFVQIMEDIILTLPKN 270
           ++++ATPGR+ D+ ++    +D       + ++VLDEAD+LL   F   +  I+  LPK 
Sbjct: 136 NIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLPKQ 195

Query: 271 RQILLYSATFPLSVQKFMNSHLQKPYEINLME--------ELTLKGVTQYYAYVTERQKV 322
           R+  L+SAT    V+  + + L+ P  +++ E        + T   +  YY      +K 
Sbjct: 196 RRTGLFSATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTPSRLENYYMVCKADEKF 255

Query: 323 HCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQL--GYSCFYIHAKMRQEHRNRVFHDF 380
           + L       +  + ++F ++   VE   K +  L  G     IH KM+ + RN++F +F
Sbjct: 256 NQLVHFLRNHKQEKHLVFFSTCACVEYYGKALEVLVKGVKIMCIHGKMKYK-RNKIFMEF 314

Query: 381 RNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAI 435
           R      LVCTD+  RGIDI  VN V+ +D P  A  ++HR GR+ R GH G A+
Sbjct: 315 RKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSAL 369


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  180 bits (457), Expect = 2e-45
 Identities = 120/393 (30%), Positives = 204/393 (51%), Gaps = 26/393 (6%)

Query: 106 ELLMGIFEMG-WEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL--------- 155
           E++MG  E+  + +P+P+Q+ +IPI    RD++A A+ G+GK+ A+L+P+L         
Sbjct: 187 EIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPG 246

Query: 156 ERLDLKKDNIQ---------AMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLR 206
           E L   K+N +         ++V+ PTRELA+Q+ +   + S +    +     GG ++ 
Sbjct: 247 EALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFS-YRSRVRPCVVYGGADIG 305

Query: 207 DDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIIL- 265
             I  L+   H+++ATPGR++D++++G   +D  + +VLDEAD++L   F   +  I+  
Sbjct: 306 QQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQ 365

Query: 266 -TLPKN--RQILLYSATFPLSVQKFMNSHLQKPYEINL-MEELTLKGVTQYYAYVTERQK 321
            T+P    R  +++SATFP  +Q      L +   + +     T + +TQ   +V +  K
Sbjct: 366 DTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDK 425

Query: 322 -VHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDF 380
               L+ L +    + +++F  + +  + L   +   GY+C  IH    Q  R    H F
Sbjct: 426 RSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQF 485

Query: 381 RNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITY 440
           R+G    LV T +  RG+DI  V  VINFD P   E Y+HRIGR+GR G+LGLA +    
Sbjct: 486 RSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNE 545

Query: 441 DDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEY 473
            +    K + + L    + +PS ++   Y   Y
Sbjct: 546 KNMNITKDLLDLLVEAKQEVPSWLENMAYEHHY 578


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,692,924
Number of Sequences: 37866
Number of extensions: 776028
Number of successful extensions: 2607
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 72
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2336
Number of HSP's gapped (non-prelim): 126
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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