Guide to the Human Genome
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Search of human proteins with 164419732

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo
sapiens]
         (483 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sap...   960   0.0  
gi|8922886 DDX19-like protein [Homo sapiens]                          622   e-178
gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H...   620   e-178
gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [...   555   e-158
gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [...   538   e-153
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   265   9e-71
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   264   2e-70
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   256   3e-68
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   211   1e-54
gi|4758112 HLA-B associated transcript 1 [Homo sapiens]               187   2e-47
gi|18375623 HLA-B associated transcript 1 [Homo sapiens]              187   2e-47
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi...   186   4e-47
gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo sapi...   179   7e-45
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   163   4e-40
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   155   8e-38
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   155   8e-38
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         149   4e-36
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          149   4e-36
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   149   6e-36
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   149   6e-36
gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]   149   6e-36
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   147   3e-35
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    146   4e-35
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   145   6e-35
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   145   6e-35
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   145   6e-35
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            143   4e-34
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            143   4e-34
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   142   5e-34
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   142   5e-34

>gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo
           sapiens]
          Length = 483

 Score =  960 bits (2481), Expect = 0.0
 Identities = 483/483 (100%), Positives = 483/483 (100%)

Query: 1   MASLLWGGDAGAAESERLNSHFSNLSQPRKNLWGIKSTAVRNIDGSINNINEDDEEDVVD 60
           MASLLWGGDAGAAESERLNSHFSNLSQPRKNLWGIKSTAVRNIDGSINNINEDDEEDVVD
Sbjct: 1   MASLLWGGDAGAAESERLNSHFSNLSQPRKNLWGIKSTAVRNIDGSINNINEDDEEDVVD 60

Query: 61  LAANSLLNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRP 120
           LAANSLLNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRP
Sbjct: 61  LAANSLLNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRP 120

Query: 121 SKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELA 180
           SKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELA
Sbjct: 121 SKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELA 180

Query: 181 LQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKLKLIDLTK 240
           LQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKLKLIDLTK
Sbjct: 181 LQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKLKLIDLTK 240

Query: 241 IRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAERIIPDPNVI 300
           IRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAERIIPDPNVI
Sbjct: 241 IRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAERIIPDPNVI 300

Query: 301 KLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQ 360
           KLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQ
Sbjct: 301 KLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQ 360

Query: 361 DGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQG 420
           DGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQG
Sbjct: 361 DGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQG 420

Query: 421 EEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLMKIQDHFNSSIKQLNAEDMDEIEK 480
           EEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLMKIQDHFNSSIKQLNAEDMDEIEK
Sbjct: 421 EEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLMKIQDHFNSSIKQLNAEDMDEIEK 480

Query: 481 IDY 483
           IDY
Sbjct: 481 IDY 483


>gi|8922886 DDX19-like protein [Homo sapiens]
          Length = 478

 Score =  622 bits (1603), Expect = e-178
 Identities = 299/429 (69%), Positives = 370/429 (86%), Gaps = 1/429 (0%)

Query: 54  DEEDVVDLAANSLLNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIY 113
           DEE+  D AA SLLNKLI  +LV+++++VEVLQ+DP+SPLYSVK+FEELRLK +LL+G+Y
Sbjct: 48  DEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVY 107

Query: 114 AMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCL 173
           AMGFNRPSKIQE ALPMMLA PPQNLIAQSQSGTGKTAAFVLAMLSRV   + +PQCLCL
Sbjct: 108 AMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVEPSDRYPQCLCL 167

Query: 174 APTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKL 233
           +PTYELALQTG+V+EQMGKF  ++++ YA+RGN++ RG  I++QI+IGTPGTVLDWC KL
Sbjct: 168 SPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKL 227

Query: 234 KLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAERI 293
           K ID  KI+VFVLDEADVMI TQG  D SIRIQR LP  CQMLLFSATFEDSVW FA+++
Sbjct: 228 KFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKV 287

Query: 294 IPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKW 353
           +PDPNVIKL++EE TL+ I+QYYVLC  R +K+QALCN+YG+ITI QA+IFC TR+ A W
Sbjct: 288 VPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASW 347

Query: 354 LTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNF 413
           L  E+ ++GHQV+LLSGE+ VEQRA++I+RFR+GKEKVL+TTNVCARGIDV+QV++V+NF
Sbjct: 348 LAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINF 407

Query: 414 DLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLM-KIQDHFNSSIKQLNA 472
           DLPV +   PD ETYLHRIGRTGRFGK+GLA NM++     +++ +IQ+HFN  I++L+ 
Sbjct: 408 DLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDT 467

Query: 473 EDMDEIEKI 481
           +D+DEIEKI
Sbjct: 468 DDLDEIEKI 476


>gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo
           sapiens]
          Length = 479

 Score =  620 bits (1600), Expect = e-178
 Identities = 298/434 (68%), Positives = 371/434 (85%), Gaps = 1/434 (0%)

Query: 49  NINEDDEEDVVDLAANSLLNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEEL 108
           N  + DEE+  D AA SLLNKLI  +LV+++++VEVLQ+DP+SPLYSVK+FEELRLK +L
Sbjct: 44  NAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQL 103

Query: 109 LKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFP 168
           L+G+YAMGFNRPSKIQE ALP+MLA PPQNLIAQSQSGTGKTAAFVLAMLS+V     +P
Sbjct: 104 LQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYP 163

Query: 169 QCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLD 228
           QCLCL+PTYELALQTG+V+EQMGKF  ++++ YA+RGN++ RG  I++QI+IGTPGTVLD
Sbjct: 164 QCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLD 223

Query: 229 WCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWH 288
           WC KLK ID  KI+VFVLDEADVMI TQG  D SIRIQR LP  CQMLLFSATFEDSVW 
Sbjct: 224 WCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWK 283

Query: 289 FAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTR 348
           FA++++PDPNVIKL++EE TL+ I+QYYVLC  R +K+QALCN+YG+ITI QA+IFC TR
Sbjct: 284 FAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTR 343

Query: 349 RNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVT 408
           + A WL  E+ ++GHQV+LLSGE+ VEQRA++I+RFR+GKEKVL+TTNVCARGIDV+QV+
Sbjct: 344 KTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVS 403

Query: 409 IVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLM-KIQDHFNSSI 467
           +V+NFDLPV +   PD ETYLHRIGRTGRFGK+GLA NM++     +++ +IQ+HFN  I
Sbjct: 404 VVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKI 463

Query: 468 KQLNAEDMDEIEKI 481
           ++L+ +D+DEIEKI
Sbjct: 464 ERLDTDDLDEIEKI 477


>gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2
           [Homo sapiens]
          Length = 448

 Score =  555 bits (1430), Expect = e-158
 Identities = 274/434 (63%), Positives = 343/434 (79%), Gaps = 32/434 (7%)

Query: 49  NINEDDEEDVVDLAANSLLNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEEL 108
           N  + DEE+  D AA SLLNKLI  +LV+++++VEVLQ+DP+SPLYSVK+FEELRL    
Sbjct: 44  NAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRL---- 99

Query: 109 LKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFP 168
                                      PQNLIAQSQSGTGKTAAFVLAMLS+V     +P
Sbjct: 100 ---------------------------PQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYP 132

Query: 169 QCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLD 228
           QCLCL+PTYELALQTG+V+EQMGKF  ++++ YA+RGN++ RG  I++QI+IGTPGTVLD
Sbjct: 133 QCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLD 192

Query: 229 WCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWH 288
           WC KLK ID  KI+VFVLDEADVMI TQG  D SIRIQR LP  CQMLLFSATFEDSVW 
Sbjct: 193 WCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWK 252

Query: 289 FAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTR 348
           FA++++PDPNVIKL++EE TL+ I+QYYVLC  R +K+QALCN+YG+ITI QA+IFC TR
Sbjct: 253 FAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTR 312

Query: 349 RNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVT 408
           + A WL  E+ ++GHQV+LLSGE+ VEQRA++I+RFR+GKEKVL+TTNVCARGIDV+QV+
Sbjct: 313 KTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVS 372

Query: 409 IVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLM-KIQDHFNSSI 467
           +V+NFDLPV +   PD ETYLHRIGRTGRFGK+GLA NM++     +++ +IQ+HFN  I
Sbjct: 373 VVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKI 432

Query: 468 KQLNAEDMDEIEKI 481
           ++L+ +D+DEIEKI
Sbjct: 433 ERLDTDDLDEIEKI 446


>gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3
           [Homo sapiens]
          Length = 370

 Score =  538 bits (1385), Expect = e-153
 Identities = 256/368 (69%), Positives = 315/368 (85%), Gaps = 1/368 (0%)

Query: 115 MGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRVNALELFPQCLCLA 174
           MGFNRPSKIQE ALP+MLA PPQNLIAQSQSGTGKTAAFVLAMLS+V     +PQCLCL+
Sbjct: 1   MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60

Query: 175 PTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQIIIGTPGTVLDWCFKLK 234
           PTYELALQTG+V+EQMGKF  ++++ YA+RGN++ RG  I++QI+IGTPGTVLDWC KLK
Sbjct: 61  PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLK 120

Query: 235 LIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAERII 294
            ID  KI+VFVLDEADVMI TQG  D SIRIQR LP  CQMLLFSATFEDSVW FA++++
Sbjct: 121 FIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVV 180

Query: 295 PDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWL 354
           PDPNVIKL++EE TL+ I+QYYVLC  R +K+QALCN+YG+ITI QA+IFC TR+ A WL
Sbjct: 181 PDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWL 240

Query: 355 TVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFD 414
             E+ ++GHQV+LLSGE+ VEQRA++I+RFR+GKEKVL+TTNVCARGIDV+QV++V+NFD
Sbjct: 241 AAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD 300

Query: 415 LPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLM-KIQDHFNSSIKQLNAE 473
           LPV +   PD ETYLHRIGRTGRFGK+GLA NM++     +++ +IQ+HFN  I++L+ +
Sbjct: 301 LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 360

Query: 474 DMDEIEKI 481
           D+DEIEKI
Sbjct: 361 DLDEIEKI 368


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  265 bits (676), Expect = 9e-71
 Identities = 143/376 (38%), Positives = 237/376 (63%), Gaps = 14/376 (3%)

Query: 98  TFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAM 157
           TF+ + L+E+LL+GIYA GF +PS IQ+ A+  ++    +++IAQSQSGTGKTA F +++
Sbjct: 39  TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISV 96

Query: 158 LSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIP---RGTDI 214
           L  ++      Q L LAPT ELA+Q  + +  +G + ++VQ    I G  +    R  D 
Sbjct: 97  LQCLDIQVRETQALILAPTRELAVQIQKGLLALGDY-MNVQCHACIGGTNVGEDIRKLDY 155

Query: 215 TKQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQ 274
            + ++ GTPG V D   + + +    I++ VLDEAD M++ +GF +    + R LP   Q
Sbjct: 156 GQHVVAGTPGRVFDM-IRRRSLRTRAIKMLVLDEADEMLN-KGFKEQIYDVYRYLPPATQ 213

Query: 275 MLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYG 334
           ++L SAT    +     + + DP  I ++++ELTL  I+Q++V  E  + K+  LC++Y 
Sbjct: 214 VVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYD 273

Query: 335 SITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLIT 394
           ++TI QA+IFC T+R   WLT +M +    VS + G++  ++R SI++ FR G  +VLI+
Sbjct: 274 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIS 333

Query: 395 TNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELP 454
           T+V ARG+DV QV++++N+DLP  +      E Y+HRIGR+GR+G+KG+A N ++ D++ 
Sbjct: 334 TDVWARGLDVPQVSLIINYDLPNNR------ELYIHRIGRSGRYGRKGVAINFVKNDDIR 387

Query: 455 SLMKIQDHFNSSIKQL 470
            L  I+ ++++ I ++
Sbjct: 388 ILRDIEQYYSTQIDEM 403


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  264 bits (674), Expect = 2e-70
 Identities = 157/387 (40%), Positives = 235/387 (60%), Gaps = 19/387 (4%)

Query: 96  VKTFEELRLKEELLKGIYAMGFNRPSKIQEMA-LPMMLAHPPQNLIAQSQSGTGKTAAFV 154
           V +F+++ L E LL+GIYA GF +PS IQ+ A LP +  +   ++IAQ+QSGTGKTA F 
Sbjct: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGY---DVIAQAQSGTGKTATFA 87

Query: 155 LAMLSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDI 214
           +++L ++       Q L LAPT ELA Q  +VV  +G + +       I G  +      
Sbjct: 88  ISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDY-MGASCHACIGGTNVRAEVQK 146

Query: 215 TKQ----IIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALP 270
            +     II+GTPG V D   + + +    I++FVLDEAD M+ ++GF D    I + L 
Sbjct: 147 LQMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEML-SRGFKDQIYDIFQKLN 204

Query: 271 SECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALC 330
           S  Q++L SAT    V    ++ + DP  I ++KEELTL  IRQ+Y+  E  + K   LC
Sbjct: 205 SNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLC 264

Query: 331 NIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEK 390
           ++Y ++TI QA+IF  TRR   WLT +M      VS + G++  ++R  I++ FR G  +
Sbjct: 265 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 324

Query: 391 VLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEV 450
           VLITT++ ARGIDV+QV++V+N+DLP  +      E Y+HRIGR GRFG+KG+A NM+  
Sbjct: 325 VLITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINMVTE 378

Query: 451 DELPSLMKIQDHFNSSIKQ--LNAEDM 475
           ++  +L  I+  +N+SI++  LN  D+
Sbjct: 379 EDKRTLRDIETFYNTSIEEMPLNVADL 405


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  256 bits (654), Expect = 3e-68
 Identities = 149/380 (39%), Positives = 231/380 (60%), Gaps = 17/380 (4%)

Query: 96  VKTFEELRLKEELLKGIYAMGFNRPSKIQEMAL-PMMLAHPPQNLIAQSQSGTGKTAAFV 154
           V  F+++ LKE LL+GIYA GF +PS IQ+ A+ P +  +   ++IAQ+QSGTGKTA F 
Sbjct: 32  VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGY---DVIAQAQSGTGKTATFA 88

Query: 155 LAMLSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRG----NRIPR 210
           +++L ++       Q L LAPT ELA Q  +V+  +G + +       I G    N + +
Sbjct: 89  ISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDY-MGATCHACIGGTNVRNEMQK 147

Query: 211 GTDITKQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALP 270
                  I++GTPG V D   + + +    I++FVLDEAD M+ ++GF D    I + L 
Sbjct: 148 LQAEAPHIVVGTPGRVFDMLNR-RYLSPKWIKMFVLDEADEML-SRGFKDQIYEIFQKLN 205

Query: 271 SECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALC 330
           +  Q++L SAT    V    ++ + DP  I ++KEELTL  I+Q+Y+  E  + K   LC
Sbjct: 206 TSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLC 265

Query: 331 NIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEK 390
           ++Y ++TI QA+IF  TRR   WLT +M      VS L G++  ++R  I++ FR G  +
Sbjct: 266 DLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSR 325

Query: 391 VLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEV 450
           VLITT++ ARGIDV+QV++V+N+DLP  +      E Y+HRIGR GRFG+KG+A N +  
Sbjct: 326 VLITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINFVTE 379

Query: 451 DELPSLMKIQDHFNSSIKQL 470
           ++   L  I+  +N++++++
Sbjct: 380 EDKRILRDIETFYNTTVEEM 399


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  211 bits (537), Expect = 1e-54
 Identities = 132/375 (35%), Positives = 210/375 (56%), Gaps = 15/375 (4%)

Query: 99  FEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAML 158
           FE+  LK ELL GI+ MG+ +PS IQE ++P+ L+   ++++A++++GTGK+ A+++ +L
Sbjct: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSG--RDILARAKNGTGKSGAYLIPLL 155

Query: 159 SRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGT---DIT 215
            R++  +   Q + + PT ELALQ  ++  Q+ K     +VM    G  +       D T
Sbjct: 156 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDT 215

Query: 216 KQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQM 275
             ++I TPG +LD   K  +  +  +++ VLDEAD ++ +Q F      I   LP   Q+
Sbjct: 216 VHVVIATPGRILD-LIKKGVAKVDHVQMIVLDEADKLL-SQDFVQIMEDIILTLPKNRQI 273

Query: 276 LLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGS 335
           LL+SATF  SV  F    +  P  I L  EELTL  + QYY     R+ K   L  ++  
Sbjct: 274 LLYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVTERQ-KVHCLNTLFSR 331

Query: 336 ITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITT 395
           + I Q+IIFC + +  + L  ++ Q G+    +  ++  E R  +   FR+G  + L+ T
Sbjct: 332 LQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCT 391

Query: 396 NVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPS 455
           ++  RGID++ V +V+NFD P         ETYLHRIGR+GRFG  GLA N+I  D+  +
Sbjct: 392 DLFTRGIDIQAVNVVINFDFPKLA------ETYLHRIGRSGRFGHLGLAINLITYDDRFN 445

Query: 456 LMKIQDHFNSSIKQL 470
           L  I++   + IK +
Sbjct: 446 LKSIEEQLGTEIKPI 460


>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  187 bits (475), Expect = 2e-47
 Identities = 124/406 (30%), Positives = 211/406 (51%), Gaps = 22/406 (5%)

Query: 86  QKDPSSPLYSVKT--FEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQS 143
           +KD      S+ +  F +  LK ELL+ I   GF  PS++Q   +P  +     +++ Q+
Sbjct: 32  KKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILG--MDVLCQA 89

Query: 144 QSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAI 203
           +SG GKTA FVLA L ++  +      L +  T ELA Q  +  E+  K+  +V+V    
Sbjct: 90  KSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFF 149

Query: 204 RGNRIPRGTDITKQ----IIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFS 259
            G  I +  ++ K+    I++GTPG +L    + K ++L  I+ F+LDE D M++     
Sbjct: 150 GGLSIKKDEEVLKKNCPHIVVGTPGRILALA-RNKSLNLKHIKHFILDECDKMLEQLDMR 208

Query: 260 DHSIRIQRALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKE-ELTLNNIRQYYVL 318
                I R  P E Q+++FSAT    +     + + DP  I +  E +LTL+ ++QYYV 
Sbjct: 209 RDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVK 268

Query: 319 CEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRA 378
            +   +K + L ++   +   Q +IF ++ +    L   +++       +   +  E+R 
Sbjct: 269 LKD-NEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERL 327

Query: 379 SIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRF 438
           S  Q+F+D + ++L+ TN+  RG+D+++V I  N+D+P       D +TYLHR+ R GRF
Sbjct: 328 SRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMP------EDSDTYLHRVARAGRF 381

Query: 439 GKKGLAFNMI-EVDELPSLMKIQDHFNSSIKQLNAEDMDEIEKIDY 483
           G KGLA   + + ++   L  +QD F  +I +L     DEI+   Y
Sbjct: 382 GTKGLAITFVSDENDAKILNDVQDRFEVNISEL----PDEIDISSY 423


>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  187 bits (475), Expect = 2e-47
 Identities = 124/406 (30%), Positives = 211/406 (51%), Gaps = 22/406 (5%)

Query: 86  QKDPSSPLYSVKT--FEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQS 143
           +KD      S+ +  F +  LK ELL+ I   GF  PS++Q   +P  +     +++ Q+
Sbjct: 32  KKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILG--MDVLCQA 89

Query: 144 QSGTGKTAAFVLAMLSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAI 203
           +SG GKTA FVLA L ++  +      L +  T ELA Q  +  E+  K+  +V+V    
Sbjct: 90  KSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFF 149

Query: 204 RGNRIPRGTDITKQ----IIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFS 259
            G  I +  ++ K+    I++GTPG +L    + K ++L  I+ F+LDE D M++     
Sbjct: 150 GGLSIKKDEEVLKKNCPHIVVGTPGRILALA-RNKSLNLKHIKHFILDECDKMLEQLDMR 208

Query: 260 DHSIRIQRALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKE-ELTLNNIRQYYVL 318
                I R  P E Q+++FSAT    +     + + DP  I +  E +LTL+ ++QYYV 
Sbjct: 209 RDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVK 268

Query: 319 CEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRA 378
            +   +K + L ++   +   Q +IF ++ +    L   +++       +   +  E+R 
Sbjct: 269 LKD-NEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERL 327

Query: 379 SIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRF 438
           S  Q+F+D + ++L+ TN+  RG+D+++V I  N+D+P       D +TYLHR+ R GRF
Sbjct: 328 SRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMP------EDSDTYLHRVARAGRF 381

Query: 439 GKKGLAFNMI-EVDELPSLMKIQDHFNSSIKQLNAEDMDEIEKIDY 483
           G KGLA   + + ++   L  +QD F  +I +L     DEI+   Y
Sbjct: 382 GTKGLAITFVSDENDAKILNDVQDRFEVNISEL----PDEIDISSY 423


>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
           sapiens]
          Length = 427

 Score =  186 bits (472), Expect = 4e-47
 Identities = 116/381 (30%), Positives = 198/381 (51%), Gaps = 16/381 (4%)

Query: 99  FEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAML 158
           F +  LK ELL+ I   GF  PS++Q   +P  +     +++ Q++SG GKTA FVLA L
Sbjct: 46  FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILG--MDVLCQAKSGMGKTAVFVLATL 103

Query: 159 SRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQ- 217
            ++  +      L +  T ELA Q  +  E+  K+   V+V     G  I +  ++ K+ 
Sbjct: 104 QQIEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKN 163

Query: 218 ---IIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQ 274
              +++GTPG +L    + +   L  ++ FVLDE D M++          I R  P E Q
Sbjct: 164 CPHVVVGTPGRILA-LVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQ 222

Query: 275 MLLFSATFEDSVWHFAERIIPDPNVIKLRKE-ELTLNNIRQYYVLCEHRKDKYQALCNIY 333
            ++FSAT    +     + + DP  + +  E +LTL+ ++QYYV  +   +K + L ++ 
Sbjct: 223 CMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKD-SEKNRKLFDLL 281

Query: 334 GSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLI 393
             +   Q IIF ++ +    L   +++       +   +  E+R S  Q+F+D + ++L+
Sbjct: 282 DVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILV 341

Query: 394 TTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMI-EVDE 452
            TN+  RG+D+++V IV N+D+P       D +TYLHR+ R GRFG KGLA   + + ++
Sbjct: 342 ATNLFGRGMDIERVNIVFNYDMP------EDSDTYLHRVARAGRFGTKGLAITFVSDEND 395

Query: 453 LPSLMKIQDHFNSSIKQLNAE 473
              L  +QD F  ++ +L  E
Sbjct: 396 AKILNDVQDRFEVNVAELPEE 416


>gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo
           sapiens]
          Length = 824

 Score =  179 bits (453), Expect = 7e-45
 Identities = 116/354 (32%), Positives = 187/354 (52%), Gaps = 18/354 (5%)

Query: 99  FEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAML 158
           FE L L   +L+G+ A GF RPS +Q  A+P  L     +LI Q++SGTGKT  F    L
Sbjct: 64  FESLLLSRPVLEGLRAAGFERPSPVQLKAIP--LGRCGLDLIVQAKSGTGKTCVFSTIAL 121

Query: 159 SRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQ- 217
             +    L  Q L LAPT E+A+Q   V+  +G     ++    I G  + +     K+ 
Sbjct: 122 DSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKKC 181

Query: 218 -IIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQML 276
            I +G+PG +     +L  ++   IR+F+LDEAD +++   F +    I  +LP+  QML
Sbjct: 182 HIAVGSPGRIKQ-LIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQML 240

Query: 277 LFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCE-----HR--KDKYQAL 329
             SAT+ + + +   + + DP  ++L   + +L  ++QYY +       H+  ++K Q L
Sbjct: 241 AVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHL 300

Query: 330 CNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKE 389
             ++  I   QA++F      A+ L   +   G     +SG +   QR   + + +    
Sbjct: 301 QELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHC 360

Query: 390 KVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGL 443
           +VLI+T++ +RGID ++V +VVN D+P+      D+ETY+HRIGR GRFG  GL
Sbjct: 361 RVLISTDLTSRGIDAEKVNLVVNLDVPL------DWETYMHRIGRAGRFGTLGL 408


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  163 bits (412), Expect = 4e-40
 Identities = 119/399 (29%), Positives = 201/399 (50%), Gaps = 24/399 (6%)

Query: 98  TFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAM 157
           +F+++ L   LLK I AMGF +P+ IQ+  +P+ L    +++ A + +GTGKTAAF L +
Sbjct: 219 SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLG--KDICACAATGTGKTAAFALPV 276

Query: 158 LSRV---NALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDI 214
           L R+          + L L PT EL +Q   V  Q+ +FC ++    A+ G  +      
Sbjct: 277 LERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFC-NITTCLAVGGLDVKSQEAA 335

Query: 215 TK---QIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPS 271
            +    I+I TPG ++D         L+ I V +LDEAD M+D + F +    I R    
Sbjct: 336 LRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLD-EYFEEQMKEIIRMCSH 394

Query: 272 ECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRK--DKYQAL 329
             Q +LFSAT  D V   A   + +P  I +         +RQ ++     +  D+   +
Sbjct: 395 HRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIV 454

Query: 330 CNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKE 389
             +         ++F QT++ A  + + +   G QV  L G L+  QR   ++RF+D + 
Sbjct: 455 AALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQI 514

Query: 390 KVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIE 449
            +L+ T+V ARG+D++ V  V+NF +P         + Y+HR+GRT R G+ G + +++ 
Sbjct: 515 DILVATDVAARGLDIEGVKTVINFTMP------NTIKHYVHRVGRTARAGRAGRSVSLVG 568

Query: 450 VDELPSLMKIQDHFNSSIK-QLNAEDM-----DEIEKID 482
            DE   L +I     + +K ++  +D+     D+IEK++
Sbjct: 569 EDERKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKME 607


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  155 bits (392), Expect = 8e-38
 Identities = 112/368 (30%), Positives = 193/368 (52%), Gaps = 22/368 (5%)

Query: 96  VKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVL 155
           +K++ +  +  ++L  +   G+ +P+ IQ  A+P +++   ++LI  +++G+GKT AF+L
Sbjct: 371 IKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSG--RDLIGIAKTGSGKTIAFLL 428

Query: 156 AMLSRV---NALELF--PQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPR 210
            M   +    +LE    P  + + PT ELALQ  +  ++  K  + ++V+    G  I  
Sbjct: 429 PMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSK-TLGLRVVCVYGGTGISE 487

Query: 211 GTDITK---QIIIGTPGTVLDWCFKL--KLIDLTKIRVFVLDEADVMIDTQGFSDHSIRI 265
                K   +II+ TPG ++D       ++ +L ++   VLDEAD M D  GF    +RI
Sbjct: 488 QIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFD-MGFEPQVMRI 546

Query: 266 QRALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDK 325
              +  + Q ++FSATF  ++   A RI+  P  +++    +  +++ Q  ++ E  K K
Sbjct: 547 VDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEK-K 605

Query: 326 YQALCNIYGSIT-IGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRF 384
           +  L  + G     G  IIF   + +A  L  ++++  +    L G +    R SII  F
Sbjct: 606 FLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDF 665

Query: 385 RDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLA 444
           ++G  K+L+ T+V ARG+DVK + +VVN+  P        YE Y+HR GRTGR G KG A
Sbjct: 666 KNGTCKLLVATSVAARGLDVKHLILVVNYSCP------NHYEDYVHRAGRTGRAGNKGYA 719

Query: 445 FNMIEVDE 452
           +  I  D+
Sbjct: 720 YTFITEDQ 727


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  155 bits (392), Expect = 8e-38
 Identities = 111/389 (28%), Positives = 193/389 (49%), Gaps = 23/389 (5%)

Query: 97  KTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLA 156
           KTF++L + + L +    +G+ +P+KIQ  A+P+ L    +++I  +++G+GKT AF L 
Sbjct: 24  KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQG--RDIIGLAETGSGKTGAFALP 81

Query: 157 MLSRVNALELFPQ---CLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRG-NRIPRGT 212
           +L   NAL   PQ    L L PT ELA Q     E +G   + VQ    + G + + +  
Sbjct: 82  IL---NALLETPQRLFALVLTPTRELAFQISEQFEALGS-SIGVQSAVIVGGIDSMSQSL 137

Query: 213 DITKQ--IIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALP 270
            + K+  III TPG ++D     K  +L  ++  V+DEAD +++   F     +I + +P
Sbjct: 138 ALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMD-FETEVDKILKVIP 196

Query: 271 SECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHR-KDKYQAL 329
            + +  LFSAT    V       + +P    +  +  T+  ++QYY+    + KD Y  L
Sbjct: 197 RDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTY--L 254

Query: 330 CNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKE 389
             I   +     +IFC T  N +   + +   G     L G+++  +R   + +F+    
Sbjct: 255 VYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKAR 314

Query: 390 KVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIE 449
            +L+ T+V +RG+D+  V +VVNFD+P         + Y+HR+GRT R G+ G A   + 
Sbjct: 315 SILLATDVASRGLDIPHVDVVVNFDIPTHS------KDYIHRVGRTARAGRSGKAITFVT 368

Query: 450 VDELPSLMKIQDHFNSSIKQLNAEDMDEI 478
             ++    +I+      +     +D DE+
Sbjct: 369 QYDVELFQRIEHLIGKKLPGFPTQD-DEV 396


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  149 bits (377), Expect = 4e-36
 Identities = 121/388 (31%), Positives = 187/388 (48%), Gaps = 29/388 (7%)

Query: 96  VKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVL 155
           V  F      + ++  +    F  P+ IQ    P+ L+   ++++  +Q+G+GKT A++L
Sbjct: 170 VFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSG--RDMVGIAQTGSGKTLAYLL 227

Query: 156 AMLSRVNALELF-----PQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPR 210
             +  +N          P CL LAPT ELA Q  +V +  GK C  ++      G   P+
Sbjct: 228 PAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK-CSRLKSTCIYGG--APK 284

Query: 211 GTDITK-----QIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRI 265
           G  I       +I I TPG ++D+    K  +L +    VLDEAD M+D  GF     +I
Sbjct: 285 GPQIRDLERGVEICIATPGRLIDFLESGKT-NLRRCTYLVLDEADRMLD-MGFEPQIRKI 342

Query: 266 QRALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLN-NIRQYYVLC-EHRK 323
              +  + Q L++SAT+   V   AE  + D   I +   EL+ N NI Q   +C E  K
Sbjct: 343 VDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEK 402

Query: 324 D-KYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQ 382
           D K   L     +    + IIF +T+R    LT  M +DG     + G+ +  +R  ++ 
Sbjct: 403 DHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLN 462

Query: 383 RFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKG 442
            FR GK  +LI T+V +RG+DV+ V  V+N+D P         E Y+HRIGRT R   KG
Sbjct: 463 EFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSS------EDYVHRIGRTARSTNKG 516

Query: 443 LAFNMI---EVDELPSLMKIQDHFNSSI 467
            A+       + +   L+K+ +  N +I
Sbjct: 517 TAYTFFTPGNLKQARELIKVLEEANQAI 544


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  149 bits (377), Expect = 4e-36
 Identities = 121/388 (31%), Positives = 187/388 (48%), Gaps = 29/388 (7%)

Query: 96  VKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVL 155
           V  F      + ++  +    F  P+ IQ    P+ L+   ++++  +Q+G+GKT A++L
Sbjct: 170 VFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSG--RDMVGIAQTGSGKTLAYLL 227

Query: 156 AMLSRVNALELF-----PQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPR 210
             +  +N          P CL LAPT ELA Q  +V +  GK C  ++      G   P+
Sbjct: 228 PAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK-CSRLKSTCIYGG--APK 284

Query: 211 GTDITK-----QIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRI 265
           G  I       +I I TPG ++D+    K  +L +    VLDEAD M+D  GF     +I
Sbjct: 285 GPQIRDLERGVEICIATPGRLIDFLESGKT-NLRRCTYLVLDEADRMLD-MGFEPQIRKI 342

Query: 266 QRALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLN-NIRQYYVLC-EHRK 323
              +  + Q L++SAT+   V   AE  + D   I +   EL+ N NI Q   +C E  K
Sbjct: 343 VDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEK 402

Query: 324 D-KYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQ 382
           D K   L     +    + IIF +T+R    LT  M +DG     + G+ +  +R  ++ 
Sbjct: 403 DHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLN 462

Query: 383 RFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKG 442
            FR GK  +LI T+V +RG+DV+ V  V+N+D P         E Y+HRIGRT R   KG
Sbjct: 463 EFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSS------EDYVHRIGRTARSTNKG 516

Query: 443 LAFNMI---EVDELPSLMKIQDHFNSSI 467
            A+       + +   L+K+ +  N +I
Sbjct: 517 TAYTFFTPGNLKQARELIKVLEEANQAI 544


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  149 bits (376), Expect = 6e-36
 Identities = 120/381 (31%), Positives = 193/381 (50%), Gaps = 50/381 (13%)

Query: 96  VKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVL 155
           ++ F ++ + E ++  I    + RP+ +Q+ A+P++     ++L+A +Q+G+GKTAAF+L
Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGK--RDLMACAQTGSGKTAAFLL 234

Query: 156 AMLSRV------NALEL------------FPQCLCLAPTYELALQTGRVVEQMGKFCVDV 197
            +LS++       AL+             +P  L LAPT ELA+Q   + E+  KF    
Sbjct: 235 PILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQ---IYEEARKFSYRS 291

Query: 198 QVMYAIRGNRIPRGTDITKQI---------IIGTPGTVLDWCFKLKLIDLTKIRVFVLDE 248
           +V   +    +  G DI +QI         ++ TPG ++D   + K I L   +  VLDE
Sbjct: 292 RVRPCV----VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDE 346

Query: 249 ADVMIDTQGFSDHSIRI--QRALPSEC--QMLLFSATFEDSVWHFAERIIPDPNVIKLRK 304
           AD M+D  GF     RI  Q  +P +     ++FSATF   +   A   + +   + + +
Sbjct: 347 ADRMLD-MGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGR 405

Query: 305 EELTLNNIRQYYVLCEHRKDKYQALCNIYGSI-TIGQAIIFCQTRRNAKWLTVEMIQDGH 363
              T  NI Q  V  E   DK   L +I G+  +    ++F +T++ A  L   +  +G+
Sbjct: 406 VGSTSENITQKVVWVEDL-DKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGY 464

Query: 364 QVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEP 423
             + + G+ +   R   + +FR GK  +L+ T V ARG+D+  V  V+NFDLP       
Sbjct: 465 ACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLP------S 518

Query: 424 DYETYLHRIGRTGRFGKKGLA 444
           D E Y+HRIGRTGR G  GLA
Sbjct: 519 DIEEYVHRIGRTGRVGNLGLA 539


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  149 bits (376), Expect = 6e-36
 Identities = 120/381 (31%), Positives = 193/381 (50%), Gaps = 50/381 (13%)

Query: 96  VKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVL 155
           ++ F ++ + E ++  I    + RP+ +Q+ A+P++     ++L+A +Q+G+GKTAAF+L
Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGK--RDLMACAQTGSGKTAAFLL 234

Query: 156 AMLSRV------NALEL------------FPQCLCLAPTYELALQTGRVVEQMGKFCVDV 197
            +LS++       AL+             +P  L LAPT ELA+Q   + E+  KF    
Sbjct: 235 PILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQ---IYEEARKFSYRS 291

Query: 198 QVMYAIRGNRIPRGTDITKQI---------IIGTPGTVLDWCFKLKLIDLTKIRVFVLDE 248
           +V   +    +  G DI +QI         ++ TPG ++D   + K I L   +  VLDE
Sbjct: 292 RVRPCV----VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDE 346

Query: 249 ADVMIDTQGFSDHSIRI--QRALPSEC--QMLLFSATFEDSVWHFAERIIPDPNVIKLRK 304
           AD M+D  GF     RI  Q  +P +     ++FSATF   +   A   + +   + + +
Sbjct: 347 ADRMLD-MGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGR 405

Query: 305 EELTLNNIRQYYVLCEHRKDKYQALCNIYGSI-TIGQAIIFCQTRRNAKWLTVEMIQDGH 363
              T  NI Q  V  E   DK   L +I G+  +    ++F +T++ A  L   +  +G+
Sbjct: 406 VGSTSENITQKVVWVEDL-DKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGY 464

Query: 364 QVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEP 423
             + + G+ +   R   + +FR GK  +L+ T V ARG+D+  V  V+NFDLP       
Sbjct: 465 ACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLP------S 518

Query: 424 DYETYLHRIGRTGRFGKKGLA 444
           D E Y+HRIGRTGR G  GLA
Sbjct: 519 DIEEYVHRIGRTGRVGNLGLA 539


>gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]
          Length = 547

 Score =  149 bits (376), Expect = 6e-36
 Identities = 119/403 (29%), Positives = 198/403 (49%), Gaps = 49/403 (12%)

Query: 99  FEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAML 158
           FE + L   LL+ +  +G++RP+ IQE A+P  LA   ++L+A++++G+GKTAA+ + ML
Sbjct: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIP--LALEGKDLLARARTGSGKTAAYAIPML 66

Query: 159 SRV-------NALELFPQCLCLAPTYELALQTGRVVEQMGKFCV-DVQV--MYAIRGNRI 208
             +         +E   + L L PT ELA Q   +++Q+  +C  DV+V  + A   +  
Sbjct: 67  QLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVS 126

Query: 209 PRGTDITK-QIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQR 267
            R   + K  +++GTP  +L    +  L     + + V+DEAD++  + GF +    +  
Sbjct: 127 QRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLF-SFGFEEELKSLLC 185

Query: 268 ALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELT-LNNIRQYYVLCEHRKDKY 326
            LP   Q  L SATF + V    E I+ +P  +KL++ +L   + ++Q+ V+CE  +DK+
Sbjct: 186 HLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKF 245

Query: 327 QALCNIYG-SITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFR 385
             L  +   S+  G++++F  T   +  L + + Q      +L+GEL +  R  II +F 
Sbjct: 246 LLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFN 305

Query: 386 DGKEKVLITTNV---------------------------CARGIDVKQVTIVVNFDLPVK 418
            G    +I T+                             ARGID   V+ V+NFDLP  
Sbjct: 306 QGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLP-- 363

Query: 419 QGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLMKIQD 461
               P  E Y+HR GRT R    G+    +   E   L KI++
Sbjct: 364 ----PTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEE 402


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  147 bits (370), Expect = 3e-35
 Identities = 114/380 (30%), Positives = 189/380 (49%), Gaps = 48/380 (12%)

Query: 96  VKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVL 155
           +++F ++ + E ++  I    + RP+ +Q+ A+P++     ++L+A +Q+G+GKTAAF+L
Sbjct: 179 IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPII--KEKRDLMACAQTGSGKTAAFLL 236

Query: 156 AMLSRVNA------------------LELFPQCLCLAPTYELALQTGRVVEQMGKFCVDV 197
            +LS++ +                   + +P  L LAPT ELA+Q   + E+  KF    
Sbjct: 237 PILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQ---IYEEARKFSYRS 293

Query: 198 QVMYAIRGNRIPRGTDITKQI---------IIGTPGTVLDWCFKLKLIDLTKIRVFVLDE 248
           +V   +    +  G DI +QI         ++ TPG ++D   + K I L   +  VLDE
Sbjct: 294 RVRPCV----VYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK-IGLDFCKYLVLDE 348

Query: 249 ADVMIDTQGFSDHSIRI--QRALPSEC--QMLLFSATFEDSVWHFAERIIPDPNVIKLRK 304
           AD M+D  GF     RI  Q  +P +     ++FSATF   +   A   + +   + + +
Sbjct: 349 ADRMLD-MGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGR 407

Query: 305 EELTLNNIRQYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQ 364
              T  NI Q  V  E    +   L  +  +      ++F +T++ A  L   +  +G+ 
Sbjct: 408 VGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYA 467

Query: 365 VSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPD 424
            + + G+ +   R   + +FR GK  +L+ T V ARG+D+  V  V+NFDLP       D
Sbjct: 468 CTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLP------SD 521

Query: 425 YETYLHRIGRTGRFGKKGLA 444
            E Y+HRIGRTGR G  GLA
Sbjct: 522 IEEYVHRIGRTGRVGNLGLA 541


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  146 bits (369), Expect = 4e-35
 Identities = 117/381 (30%), Positives = 191/381 (50%), Gaps = 30/381 (7%)

Query: 96  VKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVL 155
           V  F E      ++  I    F  P+ IQ    P+ L+    +++  +Q+G+GKT +++L
Sbjct: 93  VLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSG--LDMVGVAQTGSGKTLSYLL 150

Query: 156 AMLSRVNALELF-----PQCLCLAPTYELALQTGRVVEQMGKFC-VDVQVMY--AIRGNR 207
             +  +N          P CL LAPT ELA Q  +V  +  + C +    +Y  A +G +
Sbjct: 151 PAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQ 210

Query: 208 IPRGTDITKQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQR 267
           I R  +   +I I TPG ++D+  +    +L +    VLDEAD M+D  GF     +I  
Sbjct: 211 I-RDLERGVEICIATPGRLIDF-LECGKTNLRRTTYLVLDEADRMLD-MGFEPQIRKIVD 267

Query: 268 ALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLN-NIRQYYVLCEHRKDKY 326
            +  + Q L++SAT+   V   AE  + D   I +   EL+ N NI Q   +C H  +K 
Sbjct: 268 QIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVC-HDVEKD 326

Query: 327 QALCNIYGSITI---GQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQR 383
           + L  +   I      + I+F +T+R    LT +M +DG     + G+ + ++R  ++  
Sbjct: 327 EKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNE 386

Query: 384 FRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGL 443
           F+ GK  +LI T+V +RG+DV+ V  V+N+D P         E Y+HRIGRT R  K G 
Sbjct: 387 FKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSS------EDYIHRIGRTARSTKTGT 440

Query: 444 AF------NMIEVDELPSLMK 458
           A+      N+ +V +L S+++
Sbjct: 441 AYTFFTPNNIKQVSDLISVLR 461


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  145 bits (367), Expect = 6e-35
 Identities = 107/357 (29%), Positives = 182/357 (50%), Gaps = 19/357 (5%)

Query: 99  FEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAML 158
           FE   L E L   +   G+  P+ IQ   +P+ L    ++++A + +G+GKTAAF+L ++
Sbjct: 205 FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLG--RDILASADTGSGKTAAFLLPVI 262

Query: 159 SRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQ- 217
            R       P  L L PT ELA+Q  R  +++      ++ +  + G  +P      +Q 
Sbjct: 263 MRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQH 322

Query: 218 --IIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQM 275
             +II TPG +LD   K   ++L  +++ V+DEAD M+   GF    + I   +P++CQ 
Sbjct: 323 VKVIIATPGRLLD-IIKQSSVELCGVKIVVVDEADTML-KMGFQQQVLDILENIPNDCQT 380

Query: 276 LLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEH--RKDKYQALCNIY 333
           +L SAT   S+   A +++ +P  I   ++ L   N+RQ  +  E   +K K   + N  
Sbjct: 381 ILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILN-D 439

Query: 334 GSITIGQAIIFCQTRRNAKWLT--VEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKV 391
             +     ++F   +  A  L+  V+ I     +S+ S +  +E R +I++   +G  +V
Sbjct: 440 KKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIE-RKNILKGLLEGDYEV 498

Query: 392 LITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMI 448
           +++T V  RG+D+  V +VVNFD+P    E      Y+H+IGR GR G+ G A   I
Sbjct: 499 VVSTGVLGRGLDLISVRLVVNFDMPSSMDE------YVHQIGRVGRLGQNGTAITFI 549


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  145 bits (367), Expect = 6e-35
 Identities = 105/369 (28%), Positives = 190/369 (51%), Gaps = 21/369 (5%)

Query: 99  FEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAML 158
           F+ + L   + KGI   G+  P+ IQ   +P++L    ++++A +++G+GKTA F+L M 
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVIL--DGKDVVAMARTGSGKTACFLLPMF 155

Query: 159 SRV--NALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIP---RGTD 213
            R+  ++ +   + L L+PT ELALQT +  +++GKF   ++    + G+R+        
Sbjct: 156 ERLKTHSAQTGARALILSPTRELALQTLKFTKELGKF-TGLKTALILGGDRMEDQFAALH 214

Query: 214 ITKQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSEC 273
               III TPG ++    ++ L  L  +   V DEAD + +  GF++    I   LP   
Sbjct: 215 ENPDIIIATPGRLVHVAVEMSL-KLQSVEYVVFDEADRLFE-MGFAEQLQEIIARLPGGH 272

Query: 274 QMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKD-KYQALCNI 332
           Q +LFSAT    +  FA   + +P +I+L  +      ++  + L   R+D K   L ++
Sbjct: 273 QTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLV--REDTKAAVLLHL 330

Query: 333 YGSITI--GQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEK 390
             ++     Q ++F  T+ +A++LT  +       + +   L    R   + +F  GK  
Sbjct: 331 LHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCS 390

Query: 391 VLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEV 450
            LI T++ ARG+D+  +  V+N+  P K       + +LHR+GR  R G+ G A++++  
Sbjct: 391 TLIVTDLAARGLDIPLLDNVINYSFPAKG------KLFLHRVGRVARAGRSGTAYSLVAP 444

Query: 451 DELPSLMKI 459
           DE+P L+ +
Sbjct: 445 DEIPYLLDL 453


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  145 bits (367), Expect = 6e-35
 Identities = 105/369 (28%), Positives = 190/369 (51%), Gaps = 21/369 (5%)

Query: 99  FEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAML 158
           F+ + L   + KGI   G+  P+ IQ   +P++L    ++++A +++G+GKTA F+L M 
Sbjct: 98  FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVIL--DGKDVVAMARTGSGKTACFLLPMF 155

Query: 159 SRV--NALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIP---RGTD 213
            R+  ++ +   + L L+PT ELALQT +  +++GKF   ++    + G+R+        
Sbjct: 156 ERLKTHSAQTGARALILSPTRELALQTLKFTKELGKF-TGLKTALILGGDRMEDQFAALH 214

Query: 214 ITKQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSEC 273
               III TPG ++    ++ L  L  +   V DEAD + +  GF++    I   LP   
Sbjct: 215 ENPDIIIATPGRLVHVAVEMSL-KLQSVEYVVFDEADRLFE-MGFAEQLQEIIARLPGGH 272

Query: 274 QMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKD-KYQALCNI 332
           Q +LFSAT    +  FA   + +P +I+L  +      ++  + L   R+D K   L ++
Sbjct: 273 QTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLV--REDTKAAVLLHL 330

Query: 333 YGSITI--GQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEK 390
             ++     Q ++F  T+ +A++LT  +       + +   L    R   + +F  GK  
Sbjct: 331 LHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCS 390

Query: 391 VLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEV 450
            LI T++ ARG+D+  +  V+N+  P K       + +LHR+GR  R G+ G A++++  
Sbjct: 391 TLIVTDLAARGLDIPLLDNVINYSFPAKG------KLFLHRVGRVARAGRSGTAYSLVAP 444

Query: 451 DELPSLMKI 459
           DE+P L+ +
Sbjct: 445 DEIPYLLDL 453


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  143 bits (360), Expect = 4e-34
 Identities = 112/397 (28%), Positives = 190/397 (47%), Gaps = 33/397 (8%)

Query: 67  LNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEM 126
           +  L  Q L++  H++  L+   ++P     +F      E+L+  I    + +P+ IQ  
Sbjct: 224 ITNLTPQQLIDLRHKLN-LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQ 282

Query: 127 ALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRV-NALELFPQ----CLCLAPTYELAL 181
            +P+ L+   +++I  +++G+GKTAAF+  ML  + +  EL P      + + PT EL  
Sbjct: 283 GVPVALSG--RDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQ 340

Query: 182 QTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQ---------IIIGTPGTVLDWCFK 232
           Q     ++ GK        Y +R   +  G  + +Q         I++ TPG ++D   K
Sbjct: 341 QIHAECKRFGK-------AYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHV-K 392

Query: 233 LKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAER 292
            K  +L ++   V DEAD M D  GF      I   +  + Q LLFSATF   +   A  
Sbjct: 393 KKATNLQRVSYLVFDEADRMFD-MGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARD 451

Query: 293 IIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITI-GQAIIFCQTRRNA 351
           I+ DP  +          ++ Q   +      K+  L       T  G  ++F   + NA
Sbjct: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANA 511

Query: 352 KWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVV 411
           + L   + Q+GH + LL G++   +R  +I  F+     VL+ T+V ARG+D+  +  V+
Sbjct: 512 EELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVI 571

Query: 412 NFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMI 448
           N+D+        D +T+ HRIGRTGR G+KG+A+ ++
Sbjct: 572 NYDV------ARDIDTHTHRIGRTGRAGEKGVAYTLL 602


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  143 bits (360), Expect = 4e-34
 Identities = 112/397 (28%), Positives = 190/397 (47%), Gaps = 33/397 (8%)

Query: 67  LNKLIHQSLVESSHRVEVLQKDPSSPLYSVKTFEELRLKEELLKGIYAMGFNRPSKIQEM 126
           +  L  Q L++  H++  L+   ++P     +F      E+L+  I    + +P+ IQ  
Sbjct: 224 ITNLTPQQLIDLRHKLN-LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQ 282

Query: 127 ALPMMLAHPPQNLIAQSQSGTGKTAAFVLAMLSRV-NALELFPQ----CLCLAPTYELAL 181
            +P+ L+   +++I  +++G+GKTAAF+  ML  + +  EL P      + + PT EL  
Sbjct: 283 GVPVALSG--RDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQ 340

Query: 182 QTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDITKQ---------IIIGTPGTVLDWCFK 232
           Q     ++ GK        Y +R   +  G  + +Q         I++ TPG ++D   K
Sbjct: 341 QIHAECKRFGK-------AYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHV-K 392

Query: 233 LKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALPSECQMLLFSATFEDSVWHFAER 292
            K  +L ++   V DEAD M D  GF      I   +  + Q LLFSATF   +   A  
Sbjct: 393 KKATNLQRVSYLVFDEADRMFD-MGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARD 451

Query: 293 IIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALCNIYGSITI-GQAIIFCQTRRNA 351
           I+ DP  +          ++ Q   +      K+  L       T  G  ++F   + NA
Sbjct: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANA 511

Query: 352 KWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVV 411
           + L   + Q+GH + LL G++   +R  +I  F+     VL+ T+V ARG+D+  +  V+
Sbjct: 512 EELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVI 571

Query: 412 NFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMI 448
           N+D+        D +T+ HRIGRTGR G+KG+A+ ++
Sbjct: 572 NYDV------ARDIDTHTHRIGRTGRAGEKGVAYTLL 602


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  142 bits (359), Expect = 5e-34
 Identities = 117/378 (30%), Positives = 192/378 (50%), Gaps = 37/378 (9%)

Query: 95  SVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFV 154
           ++ TFEE  L + L   I   G+ + + +Q+ ++P++LA   ++L+A +Q+G+GKTAAF+
Sbjct: 286 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAG--RDLMACAQTGSGKTAAFL 343

Query: 155 LAML----------SRVNALELFPQCLCLAPTYELALQTGRVVEQMGKF----CVDVQVM 200
           L +L          SR   L+  P+C+ +APT EL  Q   +  +  KF    CV   V+
Sbjct: 344 LPILAHMMHDGITASRFKELQE-PECIIVAPTRELVNQ---IYLEARKFSFGTCVRAVVI 399

Query: 201 YAIRGNRIPRGTDITKQ---IIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQG 257
           Y   G ++        Q   I+  TPG ++D   K K I L +I+  VLDEAD M+D  G
Sbjct: 400 YG--GTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLD-MG 455

Query: 258 FSDHSIRIQRA--LPS--ECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIR 313
           F     ++     +PS  + Q L+FSATF + +   A   +    +     +        
Sbjct: 456 FGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDV 515

Query: 314 QYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELT 373
           Q  VL   +  K + L  I  +I   + ++F +T++ A ++   + Q+    + + G+  
Sbjct: 516 QQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDRE 575

Query: 374 VEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIG 433
             +R   +  FR GK  VL+ T+V ARG+D++ V  V+NFDLP         + Y+HRIG
Sbjct: 576 QREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLP------STIDEYVHRIG 629

Query: 434 RTGRFGKKGLAFNMIEVD 451
           RTGR G  G A +  +++
Sbjct: 630 RTGRCGNTGRAISFFDLE 647


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  142 bits (359), Expect = 5e-34
 Identities = 117/378 (30%), Positives = 192/378 (50%), Gaps = 37/378 (9%)

Query: 95  SVKTFEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFV 154
           ++ TFEE  L + L   I   G+ + + +Q+ ++P++LA   ++L+A +Q+G+GKTAAF+
Sbjct: 286 AILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAG--RDLMACAQTGSGKTAAFL 343

Query: 155 LAML----------SRVNALELFPQCLCLAPTYELALQTGRVVEQMGKF----CVDVQVM 200
           L +L          SR   L+  P+C+ +APT EL  Q   +  +  KF    CV   V+
Sbjct: 344 LPILAHMMHDGITASRFKELQE-PECIIVAPTRELVNQ---IYLEARKFSFGTCVRAVVI 399

Query: 201 YAIRGNRIPRGTDITKQ---IIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQG 257
           Y   G ++        Q   I+  TPG ++D   K K I L +I+  VLDEAD M+D  G
Sbjct: 400 YG--GTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK-IGLKQIKYLVLDEADRMLD-MG 455

Query: 258 FSDHSIRIQRA--LPS--ECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIR 313
           F     ++     +PS  + Q L+FSATF + +   A   +    +     +        
Sbjct: 456 FGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDV 515

Query: 314 QYYVLCEHRKDKYQALCNIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELT 373
           Q  VL   +  K + L  I  +I   + ++F +T++ A ++   + Q+    + + G+  
Sbjct: 516 QQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDRE 575

Query: 374 VEQRASIIQRFRDGKEKVLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIG 433
             +R   +  FR GK  VL+ T+V ARG+D++ V  V+NFDLP         + Y+HRIG
Sbjct: 576 QREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLP------STIDEYVHRIG 629

Query: 434 RTGRFGKKGLAFNMIEVD 451
           RTGR G  G A +  +++
Sbjct: 630 RTGRCGNTGRAISFFDLE 647


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,895,589
Number of Sequences: 37866
Number of extensions: 700561
Number of successful extensions: 2098
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1827
Number of HSP's gapped (non-prelim): 96
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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