Guide to the Human Genome
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Search of human proteins with 163644283

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|163644283 proteasome (prosome, macropain) activator subunit
4 [Homo sapiens]
         (1843 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|163644283 proteasome (prosome, macropain) activator subunit 4...  3738   0.0  
gi|209915591 ribosomal protein S6 kinase, 52kDa, polypeptide 1 i...    37   0.23 
gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1 is...    37   0.23 
gi|195972866 keratin 10 [Homo sapiens]                                 36   0.40 
gi|239757289 PREDICTED: hypothetical protein [Homo sapiens]            33   2.0  
gi|21314671 transient receptor potential cation channel, subfami...    33   2.0  
gi|117414133 taste receptor, type 2, member 46 [Homo sapiens]          33   2.0  
gi|40354195 keratin 18 [Homo sapiens]                                  33   2.6  
gi|4557888 keratin 18 [Homo sapiens]                                   33   2.6  
gi|32455246 beta isoform of regulatory subunit A, protein phosph...    33   2.6  
gi|32455244 beta isoform of regulatory subunit A, protein phosph...    33   2.6  
gi|45430055 translokin [Homo sapiens]                                  33   2.6  
gi|71274152 hypothetical protein LOC388939 [Homo sapiens]              33   2.6  
gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]              33   3.4  
gi|178056552 non-SMC condensin I complex, subunit D2 [Homo sapiens]    33   3.4  
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      32   4.4  
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap...    32   4.4  
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...    32   4.4  
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...    32   4.4  
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...    32   4.4  
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...    32   4.4  
gi|239757898 PREDICTED: similar to testis expressed sequence 13A...    32   5.7  
gi|239752412 PREDICTED: similar to testis expressed sequence 13A...    32   5.7  
gi|169216868 PREDICTED: similar to testis expressed sequence 13A...    32   5.7  
gi|4557537 developmentally regulated GTP binding protein 2 [Homo...    32   7.5  
gi|83367077 mucin 16 [Homo sapiens]                                    32   7.5  
gi|21359945 chromosome condensation protein G [Homo sapiens]           32   7.5  
gi|55749932 desmin [Homo sapiens]                                      32   7.5  
gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens]     31   9.8  
gi|17530791 zinc finger protein 354B [Homo sapiens]                    31   9.8  

>gi|163644283 proteasome (prosome, macropain) activator subunit 4
            [Homo sapiens]
          Length = 1843

 Score = 3738 bits (9693), Expect = 0.0
 Identities = 1843/1843 (100%), Positives = 1843/1843 (100%)

Query: 1    MEPAERAGVGEPPEPGGRPEPGPRGFVPQKEIVYNKLLPYAERLDAESDLQLAQIKCNLG 60
            MEPAERAGVGEPPEPGGRPEPGPRGFVPQKEIVYNKLLPYAERLDAESDLQLAQIKCNLG
Sbjct: 1    MEPAERAGVGEPPEPGGRPEPGPRGFVPQKEIVYNKLLPYAERLDAESDLQLAQIKCNLG 60

Query: 61   RAVQLQELWPGGLFWTRKLSTYIRLYGRKFSKEDHVLFIKLLYELVSIPKLEISMMQGFA 120
            RAVQLQELWPGGLFWTRKLSTYIRLYGRKFSKEDHVLFIKLLYELVSIPKLEISMMQGFA
Sbjct: 61   RAVQLQELWPGGLFWTRKLSTYIRLYGRKFSKEDHVLFIKLLYELVSIPKLEISMMQGFA 120

Query: 121  RLLINLLKKKELLSRADLELPWRPLYDMVERILYSKTEHLGLNWFPNSVENILKTLVKSC 180
            RLLINLLKKKELLSRADLELPWRPLYDMVERILYSKTEHLGLNWFPNSVENILKTLVKSC
Sbjct: 121  RLLINLLKKKELLSRADLELPWRPLYDMVERILYSKTEHLGLNWFPNSVENILKTLVKSC 180

Query: 181  RPYFPADATAEMLEEWRPLMCPFDVTMQKAITYFEIFLPTSLPPELHHKGFKLWFDELIG 240
            RPYFPADATAEMLEEWRPLMCPFDVTMQKAITYFEIFLPTSLPPELHHKGFKLWFDELIG
Sbjct: 181  RPYFPADATAEMLEEWRPLMCPFDVTMQKAITYFEIFLPTSLPPELHHKGFKLWFDELIG 240

Query: 241  LWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPR 300
            LWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPR
Sbjct: 241  LWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPR 300

Query: 301  FLTNAYDIGHAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRL 360
            FLTNAYDIGHAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRL
Sbjct: 301  FLTNAYDIGHAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRL 360

Query: 361  PNSVVRRLHRERYKKPSWLTPVPDSHKLTDQDVTDFVQCIIQPVLLAMFSKTGSLEAAQA 420
            PNSVVRRLHRERYKKPSWLTPVPDSHKLTDQDVTDFVQCIIQPVLLAMFSKTGSLEAAQA
Sbjct: 361  PNSVVRRLHRERYKKPSWLTPVPDSHKLTDQDVTDFVQCIIQPVLLAMFSKTGSLEAAQA 420

Query: 421  LQNLALMRPELVIPPVLERTYPALETLTEPHQLTATLSCVIGVARSLVSGGRWFPEGPTH 480
            LQNLALMRPELVIPPVLERTYPALETLTEPHQLTATLSCVIGVARSLVSGGRWFPEGPTH
Sbjct: 421  LQNLALMRPELVIPPVLERTYPALETLTEPHQLTATLSCVIGVARSLVSGGRWFPEGPTH 480

Query: 481  MLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSVLQERNDLTEVERELCSAT 540
            MLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSVLQERNDLTEVERELCSAT
Sbjct: 481  MLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSVLQERNDLTEVERELCSAT 540

Query: 541  AEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKE 600
            AEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKE
Sbjct: 541  AEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKE 600

Query: 601  IFMVALQKVFNFSTSHIFETRVAGRMVADMCRAAVKCCPEESLKLFVPHCCSVITQLTMN 660
            IFMVALQKVFNFSTSHIFETRVAGRMVADMCRAAVKCCPEESLKLFVPHCCSVITQLTMN
Sbjct: 601  IFMVALQKVFNFSTSHIFETRVAGRMVADMCRAAVKCCPEESLKLFVPHCCSVITQLTMN 660

Query: 661  DDVLNDEELDKELLWNLQLLSEITRVDGRKLLLYREQLVKILQRTLHLTCKQGYTLSCNL 720
            DDVLNDEELDKELLWNLQLLSEITRVDGRKLLLYREQLVKILQRTLHLTCKQGYTLSCNL
Sbjct: 661  DDVLNDEELDKELLWNLQLLSEITRVDGRKLLLYREQLVKILQRTLHLTCKQGYTLSCNL 720

Query: 721  LHHLLRSTTLIYPTEYCSVPGGFDKPPSEYFPIKDWGKPGDLWNLGIQWHVPSSEEVSFA 780
            LHHLLRSTTLIYPTEYCSVPGGFDKPPSEYFPIKDWGKPGDLWNLGIQWHVPSSEEVSFA
Sbjct: 721  LHHLLRSTTLIYPTEYCSVPGGFDKPPSEYFPIKDWGKPGDLWNLGIQWHVPSSEEVSFA 780

Query: 781  FYLLDSFLQPELVKLQHCGDGKLEMSRDDILQSLTIVHNCLIGSGNLLPPLKGEPVTNLV 840
            FYLLDSFLQPELVKLQHCGDGKLEMSRDDILQSLTIVHNCLIGSGNLLPPLKGEPVTNLV
Sbjct: 781  FYLLDSFLQPELVKLQHCGDGKLEMSRDDILQSLTIVHNCLIGSGNLLPPLKGEPVTNLV 840

Query: 841  PSMVSLEETKLYTGLEYDLSRENHREVIATVIRKLLNHILDNSEDDTKSLFLIIKIIGDL 900
            PSMVSLEETKLYTGLEYDLSRENHREVIATVIRKLLNHILDNSEDDTKSLFLIIKIIGDL
Sbjct: 841  PSMVSLEETKLYTGLEYDLSRENHREVIATVIRKLLNHILDNSEDDTKSLFLIIKIIGDL 900

Query: 901  LQFQGSHKHEFDSRWKSFNLVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEY 960
            LQFQGSHKHEFDSRWKSFNLVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEY
Sbjct: 901  LQFQGSHKHEFDSRWKSFNLVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEY 960

Query: 961  KKIHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRQGVT 1020
            KKIHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRQGVT
Sbjct: 961  KKIHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRQGVT 1020

Query: 1021 QQQFKGALYCLLGNHSGVCLANLHDWDCIVQTWPAIVSSGLSQAMSLEKPSIVRLFDDLA 1080
            QQQFKGALYCLLGNHSGVCLANLHDWDCIVQTWPAIVSSGLSQAMSLEKPSIVRLFDDLA
Sbjct: 1021 QQQFKGALYCLLGNHSGVCLANLHDWDCIVQTWPAIVSSGLSQAMSLEKPSIVRLFDDLA 1080

Query: 1081 EKIHRQYETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGIKRQQEKNADAL 1140
            EKIHRQYETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGIKRQQEKNADAL
Sbjct: 1081 EKIHRQYETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGIKRQQEKNADAL 1140

Query: 1141 RNYENLVDTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLPLRAIRFFVENLNHDAIVV 1200
            RNYENLVDTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLPLRAIRFFVENLNHDAIVV
Sbjct: 1141 RNYENLVDTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLPLRAIRFFVENLNHDAIVV 1200

Query: 1201 RKMAISAVAGILKQLKRTHKKLTINPCEISGCPKPTQIIAGDRPDNHWLHYDSKTIPRTK 1260
            RKMAISAVAGILKQLKRTHKKLTINPCEISGCPKPTQIIAGDRPDNHWLHYDSKTIPRTK
Sbjct: 1201 RKMAISAVAGILKQLKRTHKKLTINPCEISGCPKPTQIIAGDRPDNHWLHYDSKTIPRTK 1260

Query: 1261 KEWESSCFVEKTHWGYYTWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIFDHFSDPKFVE 1320
            KEWESSCFVEKTHWGYYTWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIFDHFSDPKFVE
Sbjct: 1261 KEWESSCFVEKTHWGYYTWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIFDHFSDPKFVE 1320

Query: 1321 QLITFLSLEDRKGKDKFNPRRFCLFKGIFRNFDDAFLPVLKPHLEHLVADSHESTQRCVA 1380
            QLITFLSLEDRKGKDKFNPRRFCLFKGIFRNFDDAFLPVLKPHLEHLVADSHESTQRCVA
Sbjct: 1321 QLITFLSLEDRKGKDKFNPRRFCLFKGIFRNFDDAFLPVLKPHLEHLVADSHESTQRCVA 1380

Query: 1381 EIIAGLIRGSKHWTFEKVEKLWELLCPLLRTALSNITVETYNDWGACIATSCESRDPRKL 1440
            EIIAGLIRGSKHWTFEKVEKLWELLCPLLRTALSNITVETYNDWGACIATSCESRDPRKL
Sbjct: 1381 EIIAGLIRGSKHWTFEKVEKLWELLCPLLRTALSNITVETYNDWGACIATSCESRDPRKL 1440

Query: 1441 HWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKN 1500
            HWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKN
Sbjct: 1441 HWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKN 1500

Query: 1501 VRERIGSVLTYIFMIDVSLPNTTPTISPHVPEFTARILEKLKPLMDVDEEIQNHVMEENG 1560
            VRERIGSVLTYIFMIDVSLPNTTPTISPHVPEFTARILEKLKPLMDVDEEIQNHVMEENG
Sbjct: 1501 VRERIGSVLTYIFMIDVSLPNTTPTISPHVPEFTARILEKLKPLMDVDEEIQNHVMEENG 1560

Query: 1561 IGEEDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKR 1620
            IGEEDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKR
Sbjct: 1561 IGEEDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKR 1620

Query: 1621 DAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNE 1680
            DAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNE
Sbjct: 1621 DAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNE 1680

Query: 1681 DAVKDIRWLVISLLEDEQLEVREMAATTLSGLLQCNFLTMDSPMQIHFEQLCKTKLPKKR 1740
            DAVKDIRWLVISLLEDEQLEVREMAATTLSGLLQCNFLTMDSPMQIHFEQLCKTKLPKKR
Sbjct: 1681 DAVKDIRWLVISLLEDEQLEVREMAATTLSGLLQCNFLTMDSPMQIHFEQLCKTKLPKKR 1740

Query: 1741 KRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSPYDVPTWMPQLLMNLSAHLNDPQPIEM 1800
            KRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSPYDVPTWMPQLLMNLSAHLNDPQPIEM
Sbjct: 1741 KRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSPYDVPTWMPQLLMNLSAHLNDPQPIEM 1800

Query: 1801 TVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA 1843
            TVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA
Sbjct: 1801 TVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA 1843


>gi|209915591 ribosomal protein S6 kinase, 52kDa, polypeptide 1
            isoform b [Homo sapiens]
          Length = 1054

 Score = 36.6 bits (83), Expect = 0.23
 Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 25/162 (15%)

Query: 1047 DCIVQTWPAIVSSGLSQ-----AMSLEKPSIVRLFDDLAEKIHRQYETIGLDFTIPKSCV 1101
            D ++ T+P   + G S      +++++  S+  L D +A   +    T GL+ +   S +
Sbjct: 133  DSLIDTFPECSTEGFSSDSDLVSLTVDVDSLAELDDGMASNQNSPIRTFGLNLSSDSSAL 192

Query: 1102 ----------------EIAELLQQSKNPSINQ---ILLSPEKIKEGIKRQQEKNADALRN 1142
                            E   L   S  P + +   +  + E IK  +K+++E + +A  +
Sbjct: 193  GAVASDSEQSKTEEERESRSLFPGSLKPKLGKRDYLEKAGELIKLALKKEEEDDYEAASD 252

Query: 1143 -YENLVDTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLPL 1183
             Y   VD LL+GV+  + P + E +       L+R + +  L
Sbjct: 253  FYRKGVDLLLEGVQGESSPTRREAVKRRTAEYLMRAESISSL 294


>gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1 isoform
            a [Homo sapiens]
          Length = 1066

 Score = 36.6 bits (83), Expect = 0.23
 Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 25/162 (15%)

Query: 1047 DCIVQTWPAIVSSGLSQ-----AMSLEKPSIVRLFDDLAEKIHRQYETIGLDFTIPKSCV 1101
            D ++ T+P   + G S      +++++  S+  L D +A   +    T GL+ +   S +
Sbjct: 145  DSLIDTFPECSTEGFSSDSDLVSLTVDVDSLAELDDGMASNQNSPIRTFGLNLSSDSSAL 204

Query: 1102 ----------------EIAELLQQSKNPSINQ---ILLSPEKIKEGIKRQQEKNADALRN 1142
                            E   L   S  P + +   +  + E IK  +K+++E + +A  +
Sbjct: 205  GAVASDSEQSKTEEERESRSLFPGSLKPKLGKRDYLEKAGELIKLALKKEEEDDYEAASD 264

Query: 1143 -YENLVDTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLPL 1183
             Y   VD LL+GV+  + P + E +       L+R + +  L
Sbjct: 265  FYRKGVDLLLEGVQGESSPTRREAVKRRTAEYLMRAESISSL 306


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 35.8 bits (81), Expect = 0.40
 Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 2/89 (2%)

Query: 900 LLQFQGSHKHEFDSRWKSFNLV--KKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEG 957
           LLQ   +     D R K  N V  ++S+E  ++G ++ +  L + +  L+ ++ +LT E 
Sbjct: 221 LLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEEL 280

Query: 958 CEYKKIHQDMIRDLLRLSTSSYSQVRNKA 986
              KK H++ ++DL  +ST   +   N A
Sbjct: 281 AYLKKNHEEEMKDLRNVSTGDVNVEMNAA 309


>gi|239757289 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 545

 Score = 33.5 bits (75), Expect = 2.0
 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 21/100 (21%)

Query: 1694 LEDEQLEVREMAATTLSGLLQCNFLTMDSPMQIHFEQLCKTKLPKKRKRDPGSVGDTIPS 1753
            LE  ++E  E+     SG          SP+Q+  + L + + PK  +   GS+   +  
Sbjct: 209  LEGGEVEDPEITGDASSG--------QSSPVQVSQQPLGQAQAPKHPQGGIGSIHHGV-- 258

Query: 1754 AELVKRHAG-VLGLGACV----------LSSPYDVPTWMP 1782
            A+ V+  AG VLG+GA +          LS P   PTW P
Sbjct: 259  AQAVQEAAGSVLGVGADIGDQARLPPELLSKPKSCPTWTP 298


>gi|21314671 transient receptor potential cation channel, subfamily
           M, member 4 [Homo sapiens]
          Length = 1214

 Score = 33.5 bits (75), Expect = 2.0
 Identities = 27/119 (22%), Positives = 51/119 (42%)

Query: 860 SRENHREVIATVIRKLLNHILDNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFDSRWKSFN 919
           S E+  E   T++ K L     +SE       L + +  + +    S     D +W+SF+
Sbjct: 365 SSEDGSEEFETIVLKALVKACGSSEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFH 424

Query: 920 LVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKKIHQDMIRDLLRLSTSS 978
           L    M+  L+ + + +R L+   + L H L  + +           +IR+LL  ++ S
Sbjct: 425 LEASLMDALLNDRPEFVRLLISHGLSLGHFLTPMRLAQLYSAAPSNSLIRNLLDQASHS 483


>gi|117414133 taste receptor, type 2, member 46 [Homo sapiens]
          Length = 309

 Score = 33.5 bits (75), Expect = 2.0
 Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 33/152 (21%)

Query: 1519 LPNTTPTISPHVPEFTARILEKLKPLMDVDEEIQNHVMEENGIGEEDERTQ-GIKLLKTI 1577
            L NTT TI  ++  FT  ++  L  +  + + ++   M+ +G G +D   +  IK L+T+
Sbjct: 174  LSNTTVTILANLVPFTLTLISFLLLICSLCKHLKK--MQLHGKGSQDPSMKVHIKALQTV 231

Query: 1578 LKWLMASAGRSFSTAVT----EQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGL 1633
              +L+  A    S  ++    E L+  P+F                     C ++     
Sbjct: 232  TSFLLLCAIYFLSIIMSVWSFESLENKPVFM-------------------FCEAI---AF 269

Query: 1634 LYPHQVPLVL----QVLKQTARSSSWHARYTV 1661
             YP   P +L    + LKQT  S  WH RY V
Sbjct: 270  SYPSTHPFILIWGNKKLKQTFLSVLWHVRYWV 301


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score = 33.1 bits (74), Expect = 2.6
 Identities = 19/69 (27%), Positives = 38/69 (55%)

Query: 910 EFDSRWKSFNLVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKKIHQDMIR 969
           +F  ++++   +++S+EN +HG ++ I    I R+ L+ E+  L  E    KK H++ ++
Sbjct: 163 DFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVK 222

Query: 970 DLLRLSTSS 978
            L     SS
Sbjct: 223 GLQAQIASS 231


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score = 33.1 bits (74), Expect = 2.6
 Identities = 19/69 (27%), Positives = 38/69 (55%)

Query: 910 EFDSRWKSFNLVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKKIHQDMIR 969
           +F  ++++   +++S+EN +HG ++ I    I R+ L+ E+  L  E    KK H++ ++
Sbjct: 163 DFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVK 222

Query: 970 DLLRLSTSS 978
            L     SS
Sbjct: 223 GLQAQIASS 231


>gi|32455246 beta isoform of regulatory subunit A, protein phosphatase
            2 isoform a [Homo sapiens]
          Length = 601

 Score = 33.1 bits (74), Expect = 2.6
 Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 9/109 (8%)

Query: 1598 QLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSSWHA 1657
            +++PLF  +A  E D S   L  +A  C+S+ +Q L       LV+  L+Q A   SW  
Sbjct: 216  EIVPLFTSLASDEQD-SVRLLAVEA--CVSI-AQLLSQDDLETLVMPTLRQAAEDKSWRV 271

Query: 1658 RYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLVISLLEDEQLEVREMAA 1706
            RY V        F  L   +  +  + D+     +LL+D + EVR  AA
Sbjct: 272  RYMVADR-----FSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAA 315


>gi|32455244 beta isoform of regulatory subunit A, protein phosphatase
            2 isoform b [Homo sapiens]
          Length = 667

 Score = 33.1 bits (74), Expect = 2.6
 Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 9/109 (8%)

Query: 1598 QLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSSWHA 1657
            +++PLF  +A  E D S   L  +A  C+S+ +Q L       LV+  L+Q A   SW  
Sbjct: 216  EIVPLFTSLASDEQD-SVRLLAVEA--CVSI-AQLLSQDDLETLVMPTLRQAAEDKSWRV 271

Query: 1658 RYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLVISLLEDEQLEVREMAA 1706
            RY V        F  L   +  +  + D+     +LL+D + EVR  AA
Sbjct: 272  RYMVADR-----FSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAA 315


>gi|45430055 translokin [Homo sapiens]
          Length = 500

 Score = 33.1 bits (74), Expect = 2.6
 Identities = 22/91 (24%), Positives = 47/91 (51%), Gaps = 6/91 (6%)

Query: 923  KSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKKIHQDMIRDLLRLSTSSYSQV 982
            +++ + L   +  IR L ++R+  +  ++TL+ E  EYKK+  + I++      +S ++ 
Sbjct: 67   RAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQE----RENSKNEE 122

Query: 983  RNKAQQTFFAALGAYNFCCRDIIPLVLEFLR 1013
                Q+     L A N C  +++   LE++R
Sbjct: 123  SKHNQELTSQLLAAENKC--NLLEKQLEYMR 151


>gi|71274152 hypothetical protein LOC388939 [Homo sapiens]
          Length = 1288

 Score = 33.1 bits (74), Expect = 2.6
 Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 9/112 (8%)

Query: 1480 PELLHRLLKYLEPKLTQVYKNVRERIGSVL----TYIFMIDVSLPNTTPTISPHVPEFTA 1535
            P LL +LL+Y   KL  +   V    GS L    +Y+      L N   T   +V E   
Sbjct: 264  PNLLQQLLQYTVSKLQVLNGTVASLTGSFLEGSSSYLHSTATHLENKLST-KRNVDERLL 322

Query: 1536 RILEKLKPLMD--VDEEIQNHVM--EENGIGEEDERTQGIKLLKTILKWLMA 1583
            R L +L+ L     D  +Q   +  E++GIG ++E  Q +  L     W +A
Sbjct: 323  RALRQLESLASGCGDPGVQGLPLCSEDSGIGADNESVQSVDKLGKQTSWDLA 374


>gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]
          Length = 991

 Score = 32.7 bits (73), Expect = 3.4
 Identities = 25/72 (34%), Positives = 30/72 (41%), Gaps = 13/72 (18%)

Query: 5   ERAGVGEPP--------EPGGRPEPGPRGFVPQKEIVYNKLLPYAERLDAESDLQLAQIK 56
           ER G  EPP        E G  P PGPRG VP     Y    P  +   +     LA+  
Sbjct: 686 ERGGEHEPPSRPCGLLDEDGSEPLPGPRGEVPGGSAHYGGPSPEKKAKSSSGGSSLAK-- 743

Query: 57  CNLGRAVQLQEL 68
              GRA + Q+L
Sbjct: 744 ---GRASKKQQL 752


>gi|178056552 non-SMC condensin I complex, subunit D2 [Homo sapiens]
          Length = 1401

 Score = 32.7 bits (73), Expect = 3.4
 Identities = 49/188 (26%), Positives = 79/188 (42%), Gaps = 31/188 (16%)

Query: 1429 ATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLK 1488
            AT C+S+    L  LF +L +SPL       +    L V  G LA    R P L+     
Sbjct: 1049 ATFCDSQ----LRLLFTMLEKSPLP------IVRSNLMVATGDLAI---RFPNLVDPWTP 1095

Query: 1489 YLEPKLTQVYKNVRERIGSVLTYIFMID------------VSLPNTTPTISPHVPEFTAR 1536
            +L  +L    + VR+  G V+T++ + D            V L +  P I+     F   
Sbjct: 1096 HLYARLRDPAQQVRKTAGLVMTHLILKDMVKVKGQVSEMAVLLIDPEPQIAALAKNFFNE 1155

Query: 1537 ILEKLKPLMDVDEEIQNHVME-ENGIGEEDERTQGIKLLKTILK-----WLMASAGRSFS 1590
            +  K   + ++  +I + + + E G+ EE   T   +LL  I K      L+    + F 
Sbjct: 1156 LSHKGNAIYNLLPDIISRLSDPELGVEEEPFHTIMKQLLSYITKDKQTESLVEKLCQRFR 1215

Query: 1591 TAVTEQLQ 1598
            T+ TE+ Q
Sbjct: 1216 TSRTERQQ 1223


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 32.3 bits (72), Expect = 4.4
 Identities = 13/23 (56%), Positives = 15/23 (65%)

Query: 3   PAERAGVGEPPEPGGRPEPGPRG 25
           P  R G GEP + G + EPGPRG
Sbjct: 425 PGLRGGAGEPGKNGAKGEPGPRG 447


>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sapiens]
          Length = 432

 Score = 32.3 bits (72), Expect = 4.4
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 1081 EKIHRQYETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGIKRQQEKNADAL 1140
            E++H Q E   L     + C +   L +Q K P   ++L   EK+ E  +RQ+E+  + L
Sbjct: 213  ERLHEQEER--LCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQ--ERL 268

Query: 1141 RNYENLVDTLLDGVEQRNLPWKFEHI 1166
               E L+D + + +EQ  L  + E +
Sbjct: 269  LERERLLDEVEELLEQERLRQQDERL 294


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sapiens]
          Length = 479

 Score = 32.3 bits (72), Expect = 4.4
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 1081 EKIHRQYETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGIKRQQEKNADAL 1140
            E++H Q E   L     + C +   L +Q K P   ++L   EK+ E  +RQ+E+  + L
Sbjct: 248  ERLHEQEER--LCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQ--ERL 303

Query: 1141 RNYENLVDTLLDGVEQRNLPWKFEHI 1166
               E L+D + + +EQ  L  + E +
Sbjct: 304  LERERLLDEVEELLEQERLRQQDERL 329


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
           sapiens]
          Length = 828

 Score = 32.3 bits (72), Expect = 4.4
 Identities = 13/24 (54%), Positives = 15/24 (62%)

Query: 2   EPAERAGVGEPPEPGGRPEPGPRG 25
           EP  +   GEP +PG   EPGPRG
Sbjct: 547 EPGRKGEKGEPADPGPPGEPGPRG 570


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
           sapiens]
          Length = 918

 Score = 32.3 bits (72), Expect = 4.4
 Identities = 13/24 (54%), Positives = 15/24 (62%)

Query: 2   EPAERAGVGEPPEPGGRPEPGPRG 25
           EP  +   GEP +PG   EPGPRG
Sbjct: 547 EPGRKGEKGEPADPGPPGEPGPRG 570


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
           sapiens]
          Length = 1019

 Score = 32.3 bits (72), Expect = 4.4
 Identities = 13/24 (54%), Positives = 15/24 (62%)

Query: 2   EPAERAGVGEPPEPGGRPEPGPRG 25
           EP  +   GEP +PG   EPGPRG
Sbjct: 547 EPGRKGEKGEPADPGPPGEPGPRG 570


>gi|239757898 PREDICTED: similar to testis expressed sequence 13A
           [Homo sapiens]
          Length = 652

 Score = 32.0 bits (71), Expect = 5.7
 Identities = 19/64 (29%), Positives = 29/64 (45%)

Query: 365 VRRLHRERYKKPSWLTPVPDSHKLTDQDVTDFVQCIIQPVLLAMFSKTGSLEAAQALQNL 424
           +RR   E  K+P W  P+ DS     ++  +  Q I+       +S+ GS E AQ +  L
Sbjct: 430 IRRCKPEGPKRPQWTVPLGDSRSHIKEEGPEGPQRIVLQGDNRSYSQEGSPERAQGMATL 489

Query: 425 ALMR 428
              R
Sbjct: 490 VFSR 493


>gi|239752412 PREDICTED: similar to testis expressed sequence 13A
           [Homo sapiens]
          Length = 652

 Score = 32.0 bits (71), Expect = 5.7
 Identities = 19/64 (29%), Positives = 29/64 (45%)

Query: 365 VRRLHRERYKKPSWLTPVPDSHKLTDQDVTDFVQCIIQPVLLAMFSKTGSLEAAQALQNL 424
           +RR   E  K+P W  P+ DS     ++  +  Q I+       +S+ GS E AQ +  L
Sbjct: 430 IRRCKPEGPKRPQWTVPLGDSRSHIKEEGPEGPQRIVLQGDNRSYSQEGSPERAQGMATL 489

Query: 425 ALMR 428
              R
Sbjct: 490 VFSR 493


>gi|169216868 PREDICTED: similar to testis expressed sequence 13A
           [Homo sapiens]
          Length = 714

 Score = 32.0 bits (71), Expect = 5.7
 Identities = 19/64 (29%), Positives = 29/64 (45%)

Query: 365 VRRLHRERYKKPSWLTPVPDSHKLTDQDVTDFVQCIIQPVLLAMFSKTGSLEAAQALQNL 424
           +RR   E  K+P W  P+ DS     ++  +  Q I+       +S+ GS E AQ +  L
Sbjct: 430 IRRCKPEGPKRPQWTVPLGDSRSHIKEEGPEGPQRIVLQGDNRSYSQEGSPERAQGMATL 489

Query: 425 ALMR 428
              R
Sbjct: 490 VFSR 493


>gi|4557537 developmentally regulated GTP binding protein 2 [Homo
           sapiens]
          Length = 364

 Score = 31.6 bits (70), Expect = 7.5
 Identities = 40/182 (21%), Positives = 74/182 (40%), Gaps = 35/182 (19%)

Query: 539 ATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVEL-----GLSSTFSTI 593
           A A   D ++  +D   G ++ S LE+  E        H  ++        G+S   +  
Sbjct: 135 AVARTADVIIMMLDATKGEVQRSLLEKELESVGIRLNKHKPNIYFKPKKGGGISFNSTVT 194

Query: 594 LTQCSKEIFMVALQKVFNFSTSHIFETRVAGRMVADMCRAAVKCCPEESLKLFVPH---- 649
           LTQCS+++  + L +   F+   +F                  C P+E + + V +    
Sbjct: 195 LTQCSEKLVQLILHEYKIFNAEVLFRE---------------DCSPDEFIDVIVGNRVYM 239

Query: 650 -CCSVITQLTMNDDVLNDEELDKELLWNLQLLSEITRVDGRKLLLYREQLVKILQRTLHL 708
            C  V  ++    D ++ EE+D+      +  + +    G KL L  + L+++L   L L
Sbjct: 240 PCLYVYNKI----DQISMEEVDR----LARKPNSVVISCGMKLNL--DYLLEMLWEYLAL 289

Query: 709 TC 710
           TC
Sbjct: 290 TC 291


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 31.6 bits (70), Expect = 7.5
 Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 13/128 (10%)

Query: 727  STTLIYPTEYCSVPGGFDKPPSEYFPIKDWGKPGDLWNLGIQWHV-PSSEEVSFAFYLLD 785
            STTL     + +V  GF  P SE   ++    PGD     + W   P  EE S  F    
Sbjct: 5585 STTLFQGGTHSTVSQGF--PHSEITTLRS-RTPGD-----VSWMTTPPVEETSSGF---- 5632

Query: 786  SFLQPELVKLQHCGDGKLEMSRDDILQSLTIVHNCLIGSGNLLPPLKGEPVTNLVPSMVS 845
            S + P +           E      L    ++ + L+ + N+L     EPVT+  P++ S
Sbjct: 5633 SLMSPSMTSPSPVSSTSPESIPSSPLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPNLSS 5692

Query: 846  LEETKLYT 853
              + +L T
Sbjct: 5693 PTQERLTT 5700


>gi|21359945 chromosome condensation protein G [Homo sapiens]
          Length = 1015

 Score = 31.6 bits (70), Expect = 7.5
 Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 9/119 (7%)

Query: 1446 LLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPKLTQVYKNVRERI 1505
            +LL+  L+    +   A + ++LQG L   E  + ELLHRL        ++V  +V   +
Sbjct: 248  MLLQQGLNDRSDAVKQAMQKHLLQGWLRFSEGNILELLHRL---DVENSSEVAVSVLNAL 304

Query: 1506 GSVLTYIFMIDVSLPN------TTPTISPHVPEFTARILEKLKPLMDVDEEIQNHVMEE 1558
             S+     ++ +   N         T++P +  +   + E LK   D  EE    ++ E
Sbjct: 305  FSITPLSELVGLCKNNDGRKLIPVETLTPEIALYWCALCEYLKSKGDEGEEFLEQILPE 363


>gi|55749932 desmin [Homo sapiens]
          Length = 470

 Score = 31.6 bits (70), Expect = 7.5
 Identities = 15/51 (29%), Positives = 28/51 (54%)

Query: 921 VKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKKIHQDMIRDL 971
           +K+  EN L   +  + A  + R+ L+  + +L  E    KK+H++ IR+L
Sbjct: 200 LKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIREL 250


>gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens]
          Length = 1651

 Score = 31.2 bits (69), Expect = 9.8
 Identities = 29/125 (23%), Positives = 60/125 (48%), Gaps = 5/125 (4%)

Query: 871  VIRKLLNHILDNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFDSRWKSFNLVKKSMENRLH 930
            ++ ++L +  + +E+  K L   + +I D++       +E++   K   ++ K +EN+ +
Sbjct: 1009 LVERILQYTKERTEEH-KDLRKALCLIKDMIATVDLKVNEYEKNQKWLEILNK-IENKTY 1066

Query: 931  GKKQHIRALLIDRVMLQHELRTLTVEGCEYKKIHQDMIRDLLR-LSTSSYSQVRNKAQQT 989
             K ++    +  +  L  E RTL  +G  Y K      +D+L  L T     ++ K Q+ 
Sbjct: 1067 TKLKN--GHVFRKQALMSEERTLLYDGLVYWKTATGRFKDILALLLTDVLLFLQEKDQKY 1124

Query: 990  FFAAL 994
             FAA+
Sbjct: 1125 IFAAV 1129


>gi|17530791 zinc finger protein 354B [Homo sapiens]
          Length = 612

 Score = 31.2 bits (69), Expect = 9.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 13/97 (13%)

Query: 1070 PSIVRLFDDLAEKIHRQYETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGI 1129
            PS   L+ D+  + +R   ++GL FT PK    +  LLQQ ++P         EK   G+
Sbjct: 33   PSQRNLYRDVMLENYRNLVSLGLSFTKPK----VISLLQQGEDP------WEVEKDSSGV 82

Query: 1130 KRQQEKNADALRNYENLVDTLLDGVE---QRNLPWKF 1163
                 K+   +       D+  + +    +R+ PW F
Sbjct: 83   SSLGCKSTPKMTKSTQTQDSFQEQIRKRLKRDEPWNF 119


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,068,295
Number of Sequences: 37866
Number of extensions: 3282409
Number of successful extensions: 10143
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 10038
Number of HSP's gapped (non-prelim): 128
length of query: 1843
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1726
effective length of database: 13,817,196
effective search space: 23848480296
effective search space used: 23848480296
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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