Guide to the Human Genome
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Search of human proteins with 161169017

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|161169017 neuron navigator 2 isoform 4 [Homo sapiens]
         (1493 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|161169017 neuron navigator 2 isoform 4 [Homo sapiens]             2940   0.0  
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]             2909   0.0  
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]              2909   0.0  
gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]             2904   0.0  
gi|120953251 neuron navigator 3 [Homo sapiens]                       1720   0.0  
gi|27262622 neuron navigator 1 [Homo sapiens]                        1092   0.0  
gi|169218146 PREDICTED: similar to neuron navigator 3, partial [...  1006   0.0  
gi|239750047 PREDICTED: similar to neuron navigator 2, partial [...   929   0.0  
gi|239747580 PREDICTED: similar to NAV1 protein [Homo sapiens]        542   e-153
gi|16975496 cortactin binding protein 2 [Homo sapiens]                119   2e-26
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    97   1e-19
gi|161016767 mucin 21 [Homo sapiens]                                   74   8e-13
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            73   2e-12
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            73   2e-12
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            73   2e-12
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            73   2e-12
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            73   2e-12
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            73   2e-12
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    72   4e-12
gi|91982772 mucin 17 [Homo sapiens]                                    70   2e-11
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            67   2e-10
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            67   2e-10
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            67   2e-10
gi|167736355 mucin 4 isoform a [Homo sapiens]                          65   6e-10
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  60   2e-08
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        59   5e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        59   5e-08
gi|83367077 mucin 16 [Homo sapiens]                                    58   8e-08
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        58   8e-08
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    57   1e-07

>gi|161169017 neuron navigator 2 isoform 4 [Homo sapiens]
          Length = 1493

 Score = 2940 bits (7622), Expect = 0.0
 Identities = 1493/1493 (100%), Positives = 1493/1493 (100%)

Query: 1    MLWPRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEK 60
            MLWPRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEK
Sbjct: 1    MLWPRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEK 60

Query: 61   HSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQT 120
            HSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQT
Sbjct: 61   HSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQT 120

Query: 121  GSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDA 180
            GSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDA
Sbjct: 121  GSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDA 180

Query: 181  GRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPK 240
            GRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPK
Sbjct: 181  GRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPK 240

Query: 241  SSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI 300
            SSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI
Sbjct: 241  SSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI 300

Query: 301  DSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAA 360
            DSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAA
Sbjct: 301  DSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAA 360

Query: 361  QPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQ 420
            QPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQ
Sbjct: 361  QPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQ 420

Query: 421  QGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAV 480
            QGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAV
Sbjct: 421  QGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAV 480

Query: 481  SKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTL 540
            SKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTL
Sbjct: 481  SKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTL 540

Query: 541  SESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTS 600
            SESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTS
Sbjct: 541  SESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTS 600

Query: 601  PSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSR 660
            PSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSR
Sbjct: 601  PSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSR 660

Query: 661  TMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTT 720
            TMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTT
Sbjct: 661  TMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTT 720

Query: 721  QLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAING 780
            QLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAING
Sbjct: 721  QLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAING 780

Query: 781  VINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWL 840
            VINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWL
Sbjct: 781  VINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWL 840

Query: 841  RSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISE 900
            RSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISE
Sbjct: 841  RSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISE 900

Query: 901  CMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDR 960
            CMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDR
Sbjct: 901  CMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDR 960

Query: 961  LKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGR 1020
            LKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGR
Sbjct: 961  LKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGR 1020

Query: 1021 HVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQL 1080
            HVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQL
Sbjct: 1021 HVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQL 1080

Query: 1081 GLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLI 1140
            GLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLI
Sbjct: 1081 GLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLI 1140

Query: 1141 PKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHK 1200
            PKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHK
Sbjct: 1141 PKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHK 1200

Query: 1201 SSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIG 1260
            SSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIG
Sbjct: 1201 SSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIG 1260

Query: 1261 TMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKII 1320
            TMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKII
Sbjct: 1261 TMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKII 1320

Query: 1321 DWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVR 1380
            DWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVR
Sbjct: 1321 DWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVR 1380

Query: 1381 EGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSK 1440
            EGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSK
Sbjct: 1381 EGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSK 1440

Query: 1441 QMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL 1493
            QMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL
Sbjct: 1441 QMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL 1493


>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
          Length = 2365

 Score = 2909 bits (7542), Expect = 0.0
 Identities = 1485/1507 (98%), Positives = 1485/1507 (98%), Gaps = 22/1507 (1%)

Query: 9    SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS 68
            SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS
Sbjct: 859  SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS 918

Query: 69   LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT 128
            LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT
Sbjct: 919  LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT 978

Query: 129  AQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES 188
            AQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES
Sbjct: 979  AQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES 1038

Query: 189  KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS 248
            KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS
Sbjct: 1039 KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS 1098

Query: 249  AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS
Sbjct: 1099 AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 1158

Query: 309  AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQ 368
            AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQ
Sbjct: 1159 AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQ 1218

Query: 369  TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS 428
            TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS
Sbjct: 1219 TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS 1278

Query: 429  GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQ 488
            GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQ
Sbjct: 1279 GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQ 1338

Query: 489  SVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSES----- 543
            SVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSES     
Sbjct: 1339 SVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSP 1398

Query: 544  -----------------DPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT 586
                             DPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT
Sbjct: 1399 AASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT 1458

Query: 587  AANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDS 646
            AANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDS
Sbjct: 1459 AANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDS 1518

Query: 647  RFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRR 706
            RFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRR
Sbjct: 1519 RFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRR 1578

Query: 707  ELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIEL 766
            ELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIEL
Sbjct: 1579 ELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIEL 1638

Query: 767  LKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSN 826
            LKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSN
Sbjct: 1639 LKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSN 1698

Query: 827  IESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGST 886
            IESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGST
Sbjct: 1699 IESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGST 1758

Query: 887  PLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNR 946
            PLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNR
Sbjct: 1759 PLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNR 1818

Query: 947  MQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLL 1006
            MQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLL
Sbjct: 1819 MQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLL 1878

Query: 1007 DDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRL 1066
            DDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRL
Sbjct: 1879 DDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRL 1938

Query: 1067 FKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGL 1126
            FKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGL
Sbjct: 1939 FKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGL 1998

Query: 1127 AENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRE 1186
            AENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRE
Sbjct: 1999 AENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRE 2058

Query: 1187 LTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNG 1246
            LTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNG
Sbjct: 2059 LTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNG 2118

Query: 1247 LLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETE 1306
            LLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETE
Sbjct: 2119 LLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETE 2178

Query: 1307 ISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDL 1366
            ISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDL
Sbjct: 2179 ISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDL 2238

Query: 1367 WNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVG 1426
            WNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVG
Sbjct: 2239 WNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVG 2298

Query: 1427 FDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILD 1486
            FDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILD
Sbjct: 2299 FDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILD 2358

Query: 1487 SSLESTL 1493
            SSLESTL
Sbjct: 2359 SSLESTL 2365



 Score = 35.4 bits (80), Expect = 0.42
 Identities = 49/174 (28%), Positives = 65/174 (37%), Gaps = 22/174 (12%)

Query: 317 REPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAA--QPVS-SPAQTSLQP 373
           ++P K  L S LP  V+Q     G  S  ++      V V P A  QP   +P Q S   
Sbjct: 131 QQPQKQHLSSPLPPAVSQV---AGAPSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQ 187

Query: 374 GAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSG---S 430
                 +  PT R    G   K    +T  N + S   +N   +         PS     
Sbjct: 188 AEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKE 247

Query: 431 GVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDG 484
            + SS SS P  S N        AS  S + S P       TN S+SSA+ + G
Sbjct: 248 PLASSASSHPGMSDNAP------ASLESGSSSTP-------TNCSTSSAIPQPG 288



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 101/477 (21%), Positives = 163/477 (34%), Gaps = 90/477 (18%)

Query: 13  SSSVSSGISDTIDNLSTDDINT---SSSISSYANTPASSRKNLDVQTDAEKHSQVERN-- 67
           S + + G S T +N  +   N    S  ++S    P+S  K   + + A  H  +  N  
Sbjct: 206 SEAKTRGGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKE-PLASSASSHPGMSDNAP 264

Query: 68  -SLWSGDDVKKSDGGSDSGIKMEPGSK---WRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
            SL SG     ++  + S I  +PG+    WR           KS S K +  +S     
Sbjct: 265 ASLESGSSSTPTNCSTSSAIP-QPGAATKPWR----------SKSLSVKHSATVS----- 308

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGK---TDDAKVSEKGRLSPKASQVKRSPSDA 180
                      M   KP  P     TP   K    +   + EK +L       K      
Sbjct: 309 -----------MLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGPG 357

Query: 181 GRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVT-------VTSRSA 233
            R +  E  + LPS   +    A S       G A+    I   G+        +T++ +
Sbjct: 358 SRDTSCERLETLPSFEESEELEAAS-RMLTTVGPASSSPKIALKGIAQRTFSRALTNKKS 416

Query: 234 TLGKIPKSSALVSRSAGRKSSMDGAQN--------------QDDGYLA---LSSRTNLQY 276
           +L    K      R   ++ S D A+               +D    A   +  +++   
Sbjct: 417 SLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKSSKIA 476

Query: 277 RSLPRPSKSNSRNGAGNRSSTSSIDS----NISSKSAGLPVPKLREPSKTALGSSLPGLV 332
             +P+  K NS        S S I      ++  KS   P P  +E  ++  G    GL 
Sbjct: 477 SFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPS-KEGERSRSGKLSSGLP 535

Query: 333 NQTDKEKGI-SSDNESVASCN-------SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPT 384
            Q  +  G  SS + S+AS         ++  + ++Q VS    T+   G+    V  P 
Sbjct: 536 QQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQ 595

Query: 385 LRRLFGGKPTKQVPI------------ATAENMKNSVVISNPHATMTQQGNLDSPSG 429
            ++ +    T  V               TAE+    V +   H T T Q  L+  +G
Sbjct: 596 PQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTG 652


>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
          Length = 2429

 Score = 2909 bits (7542), Expect = 0.0
 Identities = 1485/1507 (98%), Positives = 1485/1507 (98%), Gaps = 22/1507 (1%)

Query: 9    SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS 68
            SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS
Sbjct: 923  SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS 982

Query: 69   LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT 128
            LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT
Sbjct: 983  LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT 1042

Query: 129  AQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES 188
            AQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES
Sbjct: 1043 AQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES 1102

Query: 189  KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS 248
            KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS
Sbjct: 1103 KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS 1162

Query: 249  AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS
Sbjct: 1163 AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 1222

Query: 309  AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQ 368
            AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQ
Sbjct: 1223 AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQ 1282

Query: 369  TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS 428
            TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS
Sbjct: 1283 TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS 1342

Query: 429  GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQ 488
            GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQ
Sbjct: 1343 GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQ 1402

Query: 489  SVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSES----- 543
            SVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSES     
Sbjct: 1403 SVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSP 1462

Query: 544  -----------------DPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT 586
                             DPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT
Sbjct: 1463 AASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT 1522

Query: 587  AANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDS 646
            AANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDS
Sbjct: 1523 AANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDS 1582

Query: 647  RFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRR 706
            RFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRR
Sbjct: 1583 RFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRR 1642

Query: 707  ELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIEL 766
            ELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIEL
Sbjct: 1643 ELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIEL 1702

Query: 767  LKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSN 826
            LKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSN
Sbjct: 1703 LKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSN 1762

Query: 827  IESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGST 886
            IESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGST
Sbjct: 1763 IESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGST 1822

Query: 887  PLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNR 946
            PLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNR
Sbjct: 1823 PLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNR 1882

Query: 947  MQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLL 1006
            MQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLL
Sbjct: 1883 MQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLL 1942

Query: 1007 DDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRL 1066
            DDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRL
Sbjct: 1943 DDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRL 2002

Query: 1067 FKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGL 1126
            FKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGL
Sbjct: 2003 FKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGL 2062

Query: 1127 AENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRE 1186
            AENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRE
Sbjct: 2063 AENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRE 2122

Query: 1187 LTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNG 1246
            LTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNG
Sbjct: 2123 LTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNG 2182

Query: 1247 LLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETE 1306
            LLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETE
Sbjct: 2183 LLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETE 2242

Query: 1307 ISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDL 1366
            ISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDL
Sbjct: 2243 ISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDL 2302

Query: 1367 WNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVG 1426
            WNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVG
Sbjct: 2303 WNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVG 2362

Query: 1427 FDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILD 1486
            FDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILD
Sbjct: 2363 FDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILD 2422

Query: 1487 SSLESTL 1493
            SSLESTL
Sbjct: 2423 SSLESTL 2429



 Score = 35.4 bits (80), Expect = 0.42
 Identities = 49/174 (28%), Positives = 65/174 (37%), Gaps = 22/174 (12%)

Query: 317 REPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAA--QPVS-SPAQTSLQP 373
           ++P K  L S LP  V+Q     G  S  ++      V V P A  QP   +P Q S   
Sbjct: 195 QQPQKQHLSSPLPPAVSQV---AGAPSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQ 251

Query: 374 GAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSG---S 430
                 +  PT R    G   K    +T  N + S   +N   +         PS     
Sbjct: 252 AEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKE 311

Query: 431 GVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDG 484
            + SS SS P  S N        AS  S + S P       TN S+SSA+ + G
Sbjct: 312 PLASSASSHPGMSDNAP------ASLESGSSSTP-------TNCSTSSAIPQPG 352



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 101/477 (21%), Positives = 163/477 (34%), Gaps = 90/477 (18%)

Query: 13  SSSVSSGISDTIDNLSTDDINT---SSSISSYANTPASSRKNLDVQTDAEKHSQVERN-- 67
           S + + G S T +N  +   N    S  ++S    P+S  K   + + A  H  +  N  
Sbjct: 270 SEAKTRGGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKE-PLASSASSHPGMSDNAP 328

Query: 68  -SLWSGDDVKKSDGGSDSGIKMEPGSK---WRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
            SL SG     ++  + S I  +PG+    WR           KS S K +  +S     
Sbjct: 329 ASLESGSSSTPTNCSTSSAIP-QPGAATKPWR----------SKSLSVKHSATVS----- 372

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGK---TDDAKVSEKGRLSPKASQVKRSPSDA 180
                      M   KP  P     TP   K    +   + EK +L       K      
Sbjct: 373 -----------MLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGPG 421

Query: 181 GRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVT-------VTSRSA 233
            R +  E  + LPS   +    A S       G A+    I   G+        +T++ +
Sbjct: 422 SRDTSCERLETLPSFEESEELEAAS-RMLTTVGPASSSPKIALKGIAQRTFSRALTNKKS 480

Query: 234 TLGKIPKSSALVSRSAGRKSSMDGAQN--------------QDDGYLA---LSSRTNLQY 276
           +L    K      R   ++ S D A+               +D    A   +  +++   
Sbjct: 481 SLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKSSKIA 540

Query: 277 RSLPRPSKSNSRNGAGNRSSTSSIDS----NISSKSAGLPVPKLREPSKTALGSSLPGLV 332
             +P+  K NS        S S I      ++  KS   P P  +E  ++  G    GL 
Sbjct: 541 SFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPS-KEGERSRSGKLSSGLP 599

Query: 333 NQTDKEKGI-SSDNESVASCN-------SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPT 384
            Q  +  G  SS + S+AS         ++  + ++Q VS    T+   G+    V  P 
Sbjct: 600 QQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQ 659

Query: 385 LRRLFGGKPTKQVPI------------ATAENMKNSVVISNPHATMTQQGNLDSPSG 429
            ++ +    T  V               TAE+    V +   H T T Q  L+  +G
Sbjct: 660 PQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTG 716


>gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]
          Length = 2432

 Score = 2904 bits (7528), Expect = 0.0
 Identities = 1485/1510 (98%), Positives = 1485/1510 (98%), Gaps = 25/1510 (1%)

Query: 9    SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS 68
            SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS
Sbjct: 923  SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS 982

Query: 69   LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT 128
            LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT
Sbjct: 983  LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT 1042

Query: 129  AQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES 188
            AQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES
Sbjct: 1043 AQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES 1102

Query: 189  KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS 248
            KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS
Sbjct: 1103 KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS 1162

Query: 249  AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS
Sbjct: 1163 AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 1222

Query: 309  AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQ 368
            AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQ
Sbjct: 1223 AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQ 1282

Query: 369  TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS 428
            TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS
Sbjct: 1283 TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS 1342

Query: 429  GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQ 488
            GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQ
Sbjct: 1343 GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQ 1402

Query: 489  SVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSES----- 543
            SVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSES     
Sbjct: 1403 SVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSP 1462

Query: 544  -----------------DPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT 586
                             DPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT
Sbjct: 1463 AASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT 1522

Query: 587  AANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDS 646
            AANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDS
Sbjct: 1523 AANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDS 1582

Query: 647  RFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRR 706
            RFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRR
Sbjct: 1583 RFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRR 1642

Query: 707  ELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIEL 766
            ELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIEL
Sbjct: 1643 ELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIEL 1702

Query: 767  LKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSN 826
            LKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSN
Sbjct: 1703 LKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSN 1762

Query: 827  IESDSKKKKRKNW---LRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGST 883
            IESDSKKKKRKNW   LRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGST
Sbjct: 1763 IESDSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGST 1822

Query: 884  GSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREA 943
            GSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREA
Sbjct: 1823 GSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREA 1882

Query: 944  MNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLD 1003
            MNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLD
Sbjct: 1883 MNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLD 1942

Query: 1004 MLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVV 1063
            MLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVV
Sbjct: 1943 MLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVV 2002

Query: 1064 RRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTV 1123
            RRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTV
Sbjct: 2003 RRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTV 2062

Query: 1124 KGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLRE 1183
            KGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLRE
Sbjct: 2063 KGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLRE 2122

Query: 1184 GRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEI 1243
            GRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEI
Sbjct: 2123 GRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEI 2182

Query: 1244 FNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLM 1303
            FNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLM
Sbjct: 2183 FNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLM 2242

Query: 1304 ETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWF 1363
            ETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWF
Sbjct: 2243 ETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWF 2302

Query: 1364 TDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPE 1423
            TDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPE
Sbjct: 2303 TDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPE 2362

Query: 1424 DVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDD 1483
            DVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDD
Sbjct: 2363 DVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDD 2422

Query: 1484 ILDSSLESTL 1493
            ILDSSLESTL
Sbjct: 2423 ILDSSLESTL 2432



 Score = 35.4 bits (80), Expect = 0.42
 Identities = 49/174 (28%), Positives = 65/174 (37%), Gaps = 22/174 (12%)

Query: 317 REPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAA--QPVS-SPAQTSLQP 373
           ++P K  L S LP  V+Q     G  S  ++      V V P A  QP   +P Q S   
Sbjct: 195 QQPQKQHLSSPLPPAVSQV---AGAPSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQ 251

Query: 374 GAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSG---S 430
                 +  PT R    G   K    +T  N + S   +N   +         PS     
Sbjct: 252 AEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKE 311

Query: 431 GVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDG 484
            + SS SS P  S N        AS  S + S P       TN S+SSA+ + G
Sbjct: 312 PLASSASSHPGMSDNAP------ASLESGSSSTP-------TNCSTSSAIPQPG 352



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 101/477 (21%), Positives = 163/477 (34%), Gaps = 90/477 (18%)

Query: 13  SSSVSSGISDTIDNLSTDDINT---SSSISSYANTPASSRKNLDVQTDAEKHSQVERN-- 67
           S + + G S T +N  +   N    S  ++S    P+S  K   + + A  H  +  N  
Sbjct: 270 SEAKTRGGSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKE-PLASSASSHPGMSDNAP 328

Query: 68  -SLWSGDDVKKSDGGSDSGIKMEPGSK---WRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
            SL SG     ++  + S I  +PG+    WR           KS S K +  +S     
Sbjct: 329 ASLESGSSSTPTNCSTSSAIP-QPGAATKPWR----------SKSLSVKHSATVS----- 372

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGK---TDDAKVSEKGRLSPKASQVKRSPSDA 180
                      M   KP  P     TP   K    +   + EK +L       K      
Sbjct: 373 -----------MLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAGEGPG 421

Query: 181 GRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVT-------VTSRSA 233
            R +  E  + LPS   +    A S       G A+    I   G+        +T++ +
Sbjct: 422 SRDTSCERLETLPSFEESEELEAAS-RMLTTVGPASSSPKIALKGIAQRTFSRALTNKKS 480

Query: 234 TLGKIPKSSALVSRSAGRKSSMDGAQN--------------QDDGYLA---LSSRTNLQY 276
           +L    K      R   ++ S D A+               +D    A   +  +++   
Sbjct: 481 SLKGNEKEKEKQQREKDKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMPKKSSKIA 540

Query: 277 RSLPRPSKSNSRNGAGNRSSTSSIDS----NISSKSAGLPVPKLREPSKTALGSSLPGLV 332
             +P+  K NS        S S I      ++  KS   P P  +E  ++  G    GL 
Sbjct: 541 SFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPGKSPSAPAPS-KEGERSRSGKLSSGLP 599

Query: 333 NQTDKEKGI-SSDNESVASCN-------SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPT 384
            Q  +  G  SS + S+AS         ++  + ++Q VS    T+   G+    V  P 
Sbjct: 600 QQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQ 659

Query: 385 LRRLFGGKPTKQVPI------------ATAENMKNSVVISNPHATMTQQGNLDSPSG 429
            ++ +    T  V               TAE+    V +   H T T Q  L+  +G
Sbjct: 660 PQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTG 716


>gi|120953251 neuron navigator 3 [Homo sapiens]
          Length = 2363

 Score = 1720 bits (4454), Expect = 0.0
 Identities = 927/1517 (61%), Positives = 1143/1517 (75%), Gaps = 64/1517 (4%)

Query: 9    SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS 68
            SWDDSSSVSSG+SDT+DN+STDD+NT+SS+SSY+N    SRKN  ++TD+EK S  +   
Sbjct: 879  SWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDET- 937

Query: 69   LW-SGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
             W S +++KK +   DS    + G KW+   S + ++ +K+   K +  +SQTGSWRRGM
Sbjct: 938  -WDSPEELKKPEEDFDS--HGDAGGKWKTVSSGLPEDPEKAGQ-KASLSVSQTGSWRRGM 993

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            +AQ G     ++  A   ALKTPG  KTDDAK SEKG+   K S ++RSPSDAG+SSGDE
Sbjct: 994  SAQGGAP---SRQKAGTSALKTPG--KTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDE 1048

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247
             KKP PS     TA + SFGFKK SG  +  AMIT+SG T+TS SATLGKIPKS+A+  +
Sbjct: 1049 GKKP-PSGIGRSTATS-SFGFKKPSGVGSS-AMITSSGATITSGSATLGKIPKSAAIGGK 1105

Query: 248  S-AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRN---GAGNRSSTSSIDSN 303
            S AGRK+S+DG+QNQDD  L +SS+T LQYRSLPRPSKS++       G+RSSTSSIDSN
Sbjct: 1106 SNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPGRGGHRSSTSSIDSN 1165

Query: 304  ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKG--ISSDNESVASCNSVKVNPAAQ 361
            +SSKSAG    KLREP+K   G S P  VNQTDKEK     SD+ESV+   S K +P + 
Sbjct: 1166 VSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPKSSPTSA 1225

Query: 362  PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT-KQVPIATAENMKNSVVISNPHATMTQ 420
                 AQ   QPG+KYPD+ASPT RRLFG K   K       E +K+S V+ +P  T+ +
Sbjct: 1226 SACG-AQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSSSVMPSPSTTLAR 1284

Query: 421  QGNLDSPS-GSGVLSS-----GSSSPLYSKNVDLNQS------PLASSPSSAHSAPSNSL 468
            QG+L+SPS G+G + S     GSSSPL++K  DL          LASSP+S HS  S  L
Sbjct: 1285 QGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLASSPASVHSFTSGGL 1344

Query: 469  TWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLT 528
             W  N SSSSA SKD   +QS++SLHTS ESID+ LS      H S +GL   + +   +
Sbjct: 1345 VWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSH-----HGSLSGLTTGTHEVQ-S 1398

Query: 529  PFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAA 588
              +RT SV++TLSES   LDRNTLPKKGLRYTP+S+   QE+ KEWLRSHS GGLQDT  
Sbjct: 1399 LLMRTGSVRSTLSES-MQLDRNTLPKKGLRYTPSSRQANQEEGKEWLRSHSTGGLQDTGN 1457

Query: 589  NSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRF 648
             SP  S S+++S +  +++FS L SPT ++Q +L  P+M+R++S+   D  +D Y DS+ 
Sbjct: 1458 QSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNSIPAQDSSFDLYDDSQL 1517

Query: 649  RNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSE-IRKLRRE 707
              S+ SL+E+ R +S SGSFRD  EEVHGSSLSLVSSTSS+YST EEK  SE I KLRRE
Sbjct: 1518 CGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYSTAEEKAHSEQIHKLRRE 1577

Query: 708  LDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELL 767
            L ASQEKV+ LT+QL+ANAHLVAAFE+SLGNMT RLQSLTMTAEQK+SEL ELR+TIE+L
Sbjct: 1578 LVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAEQKESELIELRETIEML 1637

Query: 768  KKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNI 827
            K QN+AAQAAI G +N P+   K        DLRIRRQHSS+SVSSINSATSHSS+GS  
Sbjct: 1638 KAQNSAAQAAIQGALNGPDHPPK--------DLRIRRQHSSESVSSINSATSHSSIGSGN 1689

Query: 828  ESDSKKKKRKNW-------LRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHN 880
            ++DSKKKK+KNW       LRSSFKQAFGKKKS K  SSHSDIEE+TDSSLP+SPKLPHN
Sbjct: 1690 DADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPASPKLPHN 1749

Query: 881  GSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQL 940
                 +  ++ S S S I EC ++EAE ++QL++ELR+KE+KLTDIRLEALSSAH LDQ+
Sbjct: 1750 AGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSSAHHLDQI 1809

Query: 941  REAMNRMQSEIEKLKAENDRLKSESQGSGC-SRAPSQVSIS---ASPRQSMGLSQHSLNL 996
            REAMNRMQ+EIE LKAENDRLK+E+  +   +R PS+ S S   +S RQS+GLS ++LN+
Sbjct: 1810 REAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGLSLNNLNI 1869

Query: 997  TESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKW 1056
            TE+ S D+LLDD G+ +  K+G R VKI+VS  +     +D +   +LIG IGVSGKTKW
Sbjct: 1870 TEAVSSDILLDDAGDATGHKDG-RSVKIIVSISKGYGRAKDQKSQAYLIGSIGVSGKTKW 1928

Query: 1057 DVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGEN 1116
            DVLDGV+RRLFKEY+  +D  + LGL+SD +  Y IG++ RS+  E PELLPCGYLVG+N
Sbjct: 1929 DVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLPCGYLVGDN 1988

Query: 1117 TTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLS 1176
              I+V +KG+ ENSLDS VF++LIPKPI QRY +LL+EH RIILSGPSGTGKTYLAN+L+
Sbjct: 1989 NIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGKTYLANKLA 2048

Query: 1177 EYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHH 1236
            EY++ + GR+ T+  IATFNVDHKSSKEL+QYL+NLA+QC+++NN V++P+VIILDNLHH
Sbjct: 2049 EYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVVIILDNLHH 2108

Query: 1237 VSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGR 1296
            V SL +IFNG LNCKY+KCPYIIGTMNQ  SS+PNL+LHHNFRWVLCANHTEPVKGFLGR
Sbjct: 2109 VGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEPVKGFLGR 2168

Query: 1297 FLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDV 1356
            +LRRKL+E EI   +RN +LVKIIDWIPK WHHLN FLE HSSSDVTIGPRLFL CP+DV
Sbjct: 2169 YLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLFLPCPMDV 2228

Query: 1357 DGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPP 1416
            +GSRVWF DLWNYS++PY+LEAVREGLQ+YG+R PWEDP+KWV+DTYPW+++    E P 
Sbjct: 2229 EGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDTYPWSSATLPQESPA 2288

Query: 1417 LLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSN 1476
            LLQLRPEDVG++  +  +E +TSK +P +D EGDPLMNMLM+LQEAANYSS QS DS+  
Sbjct: 2289 LLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSSTQSCDSE-- 2346

Query: 1477 SNSHHDDILDSSLESTL 1493
            S SHH+DILDSSLESTL
Sbjct: 2347 STSHHEDILDSSLESTL 2363



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 183/879 (20%), Positives = 320/879 (36%), Gaps = 124/879 (14%)

Query: 105  SDKSTSGKKNPVISQ----TGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKV 160
            S   +S +  P +S+      S ++ M  +  +   RT    P      P  G  DD   
Sbjct: 358  SPTPSSDRLKPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAF 417

Query: 161  SEKGRL---------------SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANS 205
            SE G +               SPK S  K +P  AG S    +KK L         N + 
Sbjct: 418  SESGEMEGFNSGLNSGGSTNSSPKVSP-KLAPPKAG-SKNLSNKKSLLQPKEKEEKNRDK 475

Query: 206  FGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSS--------ALVSRSAG--RKSSM 255
                 +         +T      TS+ A+L  IPK S        +L+  S+G  +  S 
Sbjct: 476  NKVCTEKPVKEEKDQVTEMAPKKTSKIASL--IPKGSKTTAAKKESLIPSSSGIPKPGSK 533

Query: 256  DGAQNQDDGYLALSSRTNLQYRSLP-RPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVP 314
                 Q     + +S+ + ++R+    PS+S S+     ++S SS  + +  + AG   P
Sbjct: 534  VPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASP 593

Query: 315  K---LREPSKTALGSSLPGLVNQTDKEKGISSDNESVA-------SCNSVKVNPAAQPVS 364
                    ++++  S+  G V    +++    +  +VA       S N     P+A   +
Sbjct: 594  SGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRAHSENEGTALPSADSCT 653

Query: 365  SPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKN-----SVVISNPHATMT 419
            SP +  L     Y   A   L  + G  P  +  + T +N+ +        +S+   T  
Sbjct: 654  SPTKMDL----SYSKTAKQCLEEISGEDPETR-RMRTVKNIADLRQNLEETMSSLRGTQI 708

Query: 420  QQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPL------ASSPSSAHSAPSNSLTWGTN 473
                L++   S V +  +   +   N+    +P+      A     A  APS    +   
Sbjct: 709  SHSTLETTFDSTVTTEVNGRTI--PNLTSRPTPMTWRLGQACPRLQAGDAPSLGAGY-PR 765

Query: 474  ASSSSAVSKDGLGFQSVSSLHTSCES-------IDISLSSGGVPSHNSSTGLIASSKD-D 525
            + +S  +  D   F   + L  +  S       ID+S  +      +S   +     D D
Sbjct: 766  SGTSRFIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMSSEVDVGGYMSDGD 825

Query: 526  SLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQE-------DAKEWLRSH 578
             L   +RT+ + +    +D  L+  T     +  T TS+   Q        DA  W  S 
Sbjct: 826  ILGKSLRTDDINSGYM-TDGGLNLYTRSLNRIPDTATSRDIIQRGVHDVTVDADSWDDSS 884

Query: 579  S-AGGLQDTAAN---------SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTML 628
            S + GL DT  N         S  SS S++T PS         +   + T  +  +P  L
Sbjct: 885  SVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQLRTDSEKRSTTDETWDSPEEL 944

Query: 629  RT-----HSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHG------ 677
            +       S  +A G++   +     +   +  + S ++S++GS+R G     G      
Sbjct: 945  KKPEEDFDSHGDAGGKWKTVSSGLPEDPEKAGQKASLSVSQTGSWRRGMSAQGGAPSRQK 1004

Query: 678  ---SSLSLVSSTSSVYSTPEEKCQSEIRKLRRE-LDASQ------EKVSALTTQLTANAH 727
               S+L     T    ++ + K   +   L+R   DA +      +K  +   + TA + 
Sbjct: 1005 AGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSDAGKSSGDEGKKPPSGIGRSTATSS 1064

Query: 728  LVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPE- 786
                    +G+  + + S   T     + L ++ K+  +  K NA  + +++G  N  + 
Sbjct: 1065 FGFKKPSGVGSSAM-ITSSGATITSGSATLGKIPKSAAIGGKSNAGRKTSLDGSQNQDDV 1123

Query: 787  -LNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKK---RKNWLRS 842
             L+     T Q   L    + S  S S I     H S  S+I+S+   K      + LR 
Sbjct: 1124 VLHVSSKTTLQYRSL---PRPSKSSTSGIPGRGGHRSSTSSIDSNVSSKSAGATTSKLRE 1180

Query: 843  SFKQAFGKKKSPKSASSHSDIEEMTDS-----SLPSSPK 876
              K   G+        +  + E++  S     SL  SPK
Sbjct: 1181 PTKIGSGRSSPVTVNQTDKEKEKVAVSDSESVSLSGSPK 1219


>gi|27262622 neuron navigator 1 [Homo sapiens]
          Length = 1874

 Score = 1092 bits (2824), Expect = 0.0
 Identities = 665/1539 (43%), Positives = 935/1539 (60%), Gaps = 125/1539 (8%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDV--QTDAEKHSQVE 65
            T WD+SSS+SSG+SD  DNLS+++ N SSS++S  +TP +SR+N  +  +TD+EK S  E
Sbjct: 408  TGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAE 467

Query: 66   RNSLWSGDDVKKS------DGGSDSGIKMEPG-SKWRRNPSDVSDESDKSTSGKKNPVIS 118
                W  +  +K+      D GS   +KMEPG SKWRR   +  D+S K    KK   + 
Sbjct: 468  SGLSWFSESEEKAPKKLEYDSGS---LKMEPGTSKWRRERPESCDDSSKGGELKKPISLG 524

Query: 119  QTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPS 178
              GS ++G T  V +T P T  +    ALK  G     + K ++KG+L+ K + ++RS S
Sbjct: 525  HPGSLKKGKTPPVAVTSPITHTAQ--SALKVAGK---PEGKATDKGKLAVKNTGLQRSSS 579

Query: 179  DAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKI 238
            DAGR    ++KKP PS    P+ +  SFG+KK    A G A +  +G      SATL KI
Sbjct: 580  DAGRDRLSDAKKP-PSGIARPSTSG-SFGYKKPP-PATGTATVMQTG-----GSATLSKI 631

Query: 239  PKSSAL-VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSS- 296
             KSS + V    GRK+S+D + + + G+LA  +R+N+QYRSLPRP+KS+S +  G R   
Sbjct: 632  QKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGP 691

Query: 297  ---TSSID-SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCN 352
               +SSID S +S+K  GL   +L+EP+K A G + P  VNQTD+EK  +         +
Sbjct: 692  RPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSD 751

Query: 353  SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412
            ++ +     P S+P   +  P A       PT  R            ATA++      ++
Sbjct: 752  NISLKSIGSPESTPKNQASHPTATKLAELPPTPLR------------ATAKSFVKPPSLA 799

Query: 413  NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLAS----SPSSAHSAPSNSL 468
            N         +LD PS S    +     L++ +   +  PL S    SP+   +  S S 
Sbjct: 800  N--LDKVNSNSLDLPSSSDTTHASKVPDLHATS-SASGGPLPSCFTPSPAPILNINSASF 856

Query: 469  TWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLS-------SGGVPSHNSSTGLIAS 521
            + G    S  +V K+   +  +S LH S ES+ + +S       S  VP+  +       
Sbjct: 857  SQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTE 916

Query: 522  SKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAG 581
             + + LT    + S +    +S+   DRNTLPKKGLRY    QL++QE+ KE   SH+ G
Sbjct: 917  EETEELT---WSGSPRAGQLDSNQR-DRNTLPKKGLRY----QLQSQEETKERRHSHTIG 968

Query: 582  GLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYD 641
            GL ++   S   S  ++      +   + + SPT  T      P + R++S+   +  ++
Sbjct: 969  GLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAAT-----TPRITRSNSIPTHEAAFE 1023

Query: 642  PYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSE- 700
             Y+ S+   S++SL E+ + M RSGSFRD  ++VHGS LSL SS SS YS+ EE+ QSE 
Sbjct: 1024 LYSGSQM-GSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQ 1082

Query: 701  IRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNEL 760
            IRKLRREL++SQEKV+ LT+QL+ANA+LVAAFEQSL NMT RL+ L  TAE+KD+EL +L
Sbjct: 1083 IRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDL 1142

Query: 761  RKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSH 820
            R+TI+ LKK+N+ AQA I G +N  E   K        +LRI+RQ+SSDS+SS+NS TSH
Sbjct: 1143 RETIDFLKKKNSEAQAVIQGALNASETTPK--------ELRIKRQNSSDSISSLNSITSH 1194

Query: 821  SSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMT--DSSLPSSPKLP 878
            SS+GS+ ++D+KKKK+K+WLRSSF +AF  KK PKSASS+SDIEE+   DSS PSSPKL 
Sbjct: 1195 SSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQ 1254

Query: 879  HNGSTGSTPLLRNSHSNSL-------------------ISECMDSEAETVMQLRNELRDK 919
            H  +  ++P +++S S+S+                    +E  + E + V +LR+EL +K
Sbjct: 1255 HGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEK 1314

Query: 920  EMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLK---SESQGSGCSRAPSQ 976
            EMKLTDIRLEAL+SAHQLDQLRE M+ MQ E++ LKAENDRLK     S GS   + P  
Sbjct: 1315 EMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGS 1374

Query: 977  VSISASPRQSMGLS-QHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWK 1035
             ++S SPR+S+GL+  HS   + + +    +D    C  ++E    +++VV    +   K
Sbjct: 1375 SALS-SPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVT--LRVVVRMPPQHIIK 1431

Query: 1036 EDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEI 1095
             D +   F +GC  VSGK  W +LD  V ++FK+YI  +DP S LGL+++S+ GYSI  +
Sbjct: 1432 GDLKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHV 1491

Query: 1096 KRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEH 1155
            KR   +E PE+ PC   V     ISV++KGL E  +DSLVFE+LIPKP++Q Y+SLL++H
Sbjct: 1492 KRVLDAEPPEMPPCRRGVNN---ISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKH 1548

Query: 1156 RRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQ 1215
            RR++LSGPSGTGKTYL NRL+EY+V R GRE+T+G+++TFN+  +S K+L+ YLSNLA+Q
Sbjct: 1549 RRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQ 1608

Query: 1216 CNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLH 1275
             + E    D+PLVI+LD+L    S+ E+ NG L CKYHKCPYIIGT NQ    TPN  LH
Sbjct: 1609 IDRETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLH 1668

Query: 1276 HNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLE 1335
             +FR +  +N+ EP  GFL R+LRRKL+E++        EL++++DW+PK+W+HL+ FLE
Sbjct: 1669 LSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLE 1728

Query: 1336 AHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDP 1395
             HS+SD  IGP  FLSCPI ++  R WF DLWN SIIPYL E  ++G++++G++A WEDP
Sbjct: 1729 KHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDP 1788

Query: 1396 AKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNM 1455
             +WV DT PW ++  Q +   L  L P  VG    + P E  T K   PS  + DPLM M
Sbjct: 1789 VEWVRDTLPWPSA--QQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAM 1846

Query: 1456 LMRLQEAANY-SSPQSYDSDSNSNSHHDDILDSSLESTL 1493
            L++LQEAANY  SP             + ILD +L++TL
Sbjct: 1847 LLKLQEAANYIESPD-----------RETILDPNLQATL 1874


>gi|169218146 PREDICTED: similar to neuron navigator 3, partial [Homo
            sapiens]
          Length = 733

 Score = 1006 bits (2601), Expect = 0.0
 Identities = 498/744 (66%), Positives = 606/744 (81%), Gaps = 22/744 (2%)

Query: 761  RKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSH 820
            R+TIE+LK QN+AAQAAI G +N P+   K        DLRIRRQHSS+SVSSINSATSH
Sbjct: 1    RETIEMLKAQNSAAQAAIQGALNGPDHPPK--------DLRIRRQHSSESVSSINSATSH 52

Query: 821  SSVGSNIESDSKKKKRKNW-------LRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPS 873
            SS+GS  ++DSKKKK+KNW       LRSSFKQAFGKKKS K  SSHSDIEE+TDSSLP+
Sbjct: 53   SSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELTDSSLPA 112

Query: 874  SPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSS 933
            SPKLPHN     +  ++ S S S I EC ++EAE ++QL++ELR+KE+KLTDIRLEALSS
Sbjct: 113  SPKLPHNAGDCGSASMKPSQSASAICECTEAEAEIILQLKSELREKELKLTDIRLEALSS 172

Query: 934  AHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGC-SRAPSQVSIS---ASPRQSMGL 989
            AH LDQ+REAMNRMQ+EIE LKAENDRLK+E+  +   +R PS+ S S   +S RQS+GL
Sbjct: 173  AHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSSSTSSSSSRQSLGL 232

Query: 990  SQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIG 1049
            S ++LN+TE+ S D+LLDD G+ +  K+G R VKI+VS  +     +D +   +LIG IG
Sbjct: 233  SLNNLNITEAVSSDILLDDAGDATGHKDG-RSVKIIVSISKGYGRAKDQKSQAYLIGSIG 291

Query: 1050 VSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPC 1109
            VSGKTKWDVLDGV+RRLFKEY+  +D  + LGL+SD +  Y IG++ RS+  E PELLPC
Sbjct: 292  VSGKTKWDVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIRSHNLEVPELLPC 351

Query: 1110 GYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKT 1169
            GYLVG+N  I+V +KG+ ENSLDS VF++LIPKPI QRY +LL+EH RIILSGPSGTGKT
Sbjct: 352  GYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHRIILSGPSGTGKT 411

Query: 1170 YLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVI 1229
            YLAN+L+EY++ + GR+ T+  IATFNVDHKSSKEL+QYL+NLA+QC+++NN V++P+VI
Sbjct: 412  YLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCSADNNGVELPVVI 471

Query: 1230 ILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEP 1289
            ILDNLHHV SL +IFNG LNCKY+KCPYIIGTMNQ  SS+PNL+LHHNFRWVLCANHTEP
Sbjct: 472  ILDNLHHVGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHNFRWVLCANHTEP 531

Query: 1290 VKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLF 1349
            VKGFLGR+LRRKL+E EI   +RN +LVKIIDWIPK WHHLN FLE HSSSDVTIGPRLF
Sbjct: 532  VKGFLGRYLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETHSSSDVTIGPRLF 591

Query: 1350 LSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASP 1409
            L CP+DV+GSRVWF DLWNYS++PY+LEAVREGLQ+YG+R PWEDP+KWV+DTYPW+++ 
Sbjct: 592  LPCPMDVEGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSKWVLDTYPWSSAT 651

Query: 1410 QQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQ 1469
               E P LLQLRPEDVG++  +  +E +TSK +P +D EGDPLMNMLM+LQEAANYSS Q
Sbjct: 652  LPQESPALLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLMKLQEAANYSSTQ 711

Query: 1470 SYDSDSNSNSHHDDILDSSLESTL 1493
            S DS+  S SHH+DILDSSLESTL
Sbjct: 712  SCDSE--STSHHEDILDSSLESTL 733


>gi|239750047 PREDICTED: similar to neuron navigator 2, partial [Homo
            sapiens]
          Length = 453

 Score =  929 bits (2402), Expect = 0.0
 Identities = 453/453 (100%), Positives = 453/453 (100%)

Query: 1041 HLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNT 1100
            HLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNT
Sbjct: 1    HLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNT 60

Query: 1101 SETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIIL 1160
            SETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIIL
Sbjct: 61   SETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIIL 120

Query: 1161 SGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSEN 1220
            SGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSEN
Sbjct: 121  SGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSEN 180

Query: 1221 NAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRW 1280
            NAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRW
Sbjct: 181  NAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRW 240

Query: 1281 VLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSS 1340
            VLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSS
Sbjct: 241  VLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSS 300

Query: 1341 DVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVM 1400
            DVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVM
Sbjct: 301  DVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVM 360

Query: 1401 DTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQ 1460
            DTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQ
Sbjct: 361  DTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQ 420

Query: 1461 EAANYSSPQSYDSDSNSNSHHDDILDSSLESTL 1493
            EAANYSSPQSYDSDSNSNSHHDDILDSSLESTL
Sbjct: 421  EAANYSSPQSYDSDSNSNSHHDDILDSSLESTL 453


>gi|239747580 PREDICTED: similar to NAV1 protein [Homo sapiens]
          Length = 559

 Score =  542 bits (1396), Expect = e-153
 Identities = 284/578 (49%), Positives = 386/578 (66%), Gaps = 24/578 (4%)

Query: 921  MKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLK---SESQGSGCSRAPSQV 977
            MKLTDIRLEAL+SAHQLDQLRE M+ MQ E++ LKAENDRLK     S GS   + P   
Sbjct: 1    MKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSS 60

Query: 978  SISASPRQSMGLS-QHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKE 1036
            ++S SPR+S+GL+  HS   + + +    +D    C  ++E    +++VV    +   K 
Sbjct: 61   ALS-SPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVT--LRVVVRMPPQHIIKG 117

Query: 1037 DSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIK 1096
            D +   F +GC  VSGK  W +LD  V ++FK+YI  +DP S LGL+++S+ GYSI  +K
Sbjct: 118  DLKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVK 177

Query: 1097 RSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHR 1156
            R   +E PE+ PC   V     ISV++KGL E  +DSLVFE+LIPKP++Q Y+SLL++HR
Sbjct: 178  RVLDAEPPEMPPCRRGVNN---ISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHR 234

Query: 1157 RIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQC 1216
            R++LSGPSGTGKTYL NRL+EY+V R GRE+T+G+++TFN+  +S K+L+ YLSNLA+Q 
Sbjct: 235  RLVLSGPSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQI 294

Query: 1217 NSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHH 1276
            + E    D+PLVI+LD+L    S+ E+ NG L CKYHKCPYIIGT NQ    TPN  LH 
Sbjct: 295  DRETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHL 354

Query: 1277 NFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEA 1336
            +FR +  +N+ EP  GFL R+LRRKL+E++        EL++++DW+PK+W+HL+ FLE 
Sbjct: 355  SFRMLTFSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEK 414

Query: 1337 HSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPA 1396
            HS+SD  IGP  FLSCPI ++  R WF DLWN SIIPYL E  ++G++++G++A WEDP 
Sbjct: 415  HSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPV 474

Query: 1397 KWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNML 1456
            +WV DT PW ++  Q +   L  L P  VG    + P E  T K   PS  + DPLM ML
Sbjct: 475  EWVRDTLPWPSA--QQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAML 532

Query: 1457 MRLQEAANY-SSPQSYDSDSNSNSHHDDILDSSLESTL 1493
            ++LQEAANY  SP             + ILD +L++TL
Sbjct: 533  LKLQEAANYIESPD-----------RETILDPNLQATL 559


>gi|16975496 cortactin binding protein 2 [Homo sapiens]
          Length = 1663

 Score =  119 bits (298), Expect = 2e-26
 Identities = 93/331 (28%), Positives = 159/331 (48%), Gaps = 32/331 (9%)

Query: 1078 SQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTT-ISVTVKGLAENSLDSLVF 1136
            S +GL++ S+   ++G +  S   ++    P  ++       I+V + G  E  L S+ +
Sbjct: 1043 SNIGLSARSIRSITLGNVPWS-VGQSFAQSPWDFMRKNKAEHITVLLSGPQEGCLSSVTY 1101

Query: 1137 ESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFN 1196
             S+IP  ++Q Y+ L+ ++  +I  GP G+ + Y+ ++L+  +  R+        I    
Sbjct: 1102 ASMIPLQMMQNYLRLVEQYHNVIFHGPEGSLQDYIVHQLALCLKHRQMAAGFSCEIVRAE 1161

Query: 1197 VDHKSSKE-LRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIF----------- 1244
            VD   SKE L     + A     + +     ++IIL+NL   SSL E+            
Sbjct: 1162 VDAGFSKEQLLDLFISSACLIPVKQSPSKKKIIIILENLEK-SSLSELLRDFLAPLENRS 1220

Query: 1245 ----------NGLLNCKY-HKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGF 1293
                      NGL  C Y H+  +++GT+ +A     +L +  +FRWV      EP++G 
Sbjct: 1221 TESPCTFQKGNGLSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGL 1280

Query: 1294 LGRFLRRKLMETEISGRVRNM--ELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLS 1351
            L RFLRRK++  +  G+  +    + KI+DW   VW  LN  L    + +  +GP+ FLS
Sbjct: 1281 LQRFLRRKVV-NKFKGQAPSPCDPVCKIVDWALSVWRQLNSCLARLGTPEALLGPKYFLS 1339

Query: 1352 CPIDVDGSRV---WFTDLWNYSIIPYLLEAV 1379
            CP+    ++V   W + LWN  I P + EA+
Sbjct: 1340 CPVVPGHAQVTVKWMSKLWNGVIAPRVQEAI 1370



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 78/375 (20%), Positives = 132/375 (35%), Gaps = 62/375 (16%)

Query: 168 PKASQVKRS-PSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV 226
           P A++++ + PS         S  PLPS++  PTA     G   Q+  A  +  + +   
Sbjct: 376 PSANKIEENGPSTGSTPDPTSSTPPLPSNAAPPTAQTP--GIAPQNSQAPPMHSLHS--- 430

Query: 227 TVTSRSATLGKIPKSSALVSRSAGRKSSMD----GAQNQDDGYLALSSRTNLQYRSLPRP 282
              + S   G  P+  A   R  G  +  D      Q+     ++ +SR NL  + L   
Sbjct: 431 PCANTSLHPGLNPRIQAARFRFQGNANDPDQNGNTTQSPPSRDVSPTSRDNLVAKQLA-- 488

Query: 283 SKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGIS 342
                      R++ +   S  +S  AG P              S PG+    D      
Sbjct: 489 -----------RNTVTQALSRFTSPQAGAP--------------SRPGVPPTGDVGTHPP 523

Query: 343 SDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATA 402
               S+ +    +V+    P   P +  L   ++ P    P L+ +            T 
Sbjct: 524 VGRTSLKTHGVARVDRGNPPPIPPKKPGL---SQTPSPPHPQLKVIIDSSRASN----TG 576

Query: 403 ENMKNSVVISNPHATMTQQGNLDSPSGSGVLSS----GSSSPLY--SKNVDLNQSPLASS 456
             + N  V S P +          P G+ V++      SSSP      ++DL  +P   +
Sbjct: 577 AKVDNKTVASTPSSL---------PQGNRVINEENLPKSSSPQLPPKPSIDLTVAPAGCA 627

Query: 457 PSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSST 516
            S+  ++   +    T   +  A S   L   +  +    C SI+   +S   P  + S 
Sbjct: 628 VSALATSQVGAWPAATPGLNQPACSDSSLVIPTTIAF---CSSINPVSASSCRPGASDSL 684

Query: 517 GLIASSKDDSLTPFV 531
            + AS    SLTP +
Sbjct: 685 LVTASGWSPSLTPLL 699


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 185/903 (20%), Positives = 346/903 (38%), Gaps = 55/903 (6%)

Query: 17   SSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVK 76
            ++G     D   + D +  S      N+   S  N D  ++++ +S    ++ ++ D+ K
Sbjct: 440  NTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESK 499

Query: 77   KSDGGSDS---------GIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
             +  GSDS                S    N ++ +D++DKS SGK     S + S     
Sbjct: 500  DNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSN 559

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPS-DAGRSSGD 186
            ++    +       + + +        + D+  S+    S  +     S S D+  SS  
Sbjct: 560  SSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS 619

Query: 187  ESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVS 246
               K   S S + +++++S      S S+       +S  + +S S+       SS   S
Sbjct: 620  SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679

Query: 247  RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
             S    SS D + + D    + SS ++    S    S  +S + + +  S++S DS+ SS
Sbjct: 680  SSDSSNSS-DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738

Query: 307  KSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSP 366
             S+        + S ++  S      N +D     S  ++S  S NS   N ++    S 
Sbjct: 739  NSSDSSDSS--DSSNSSDSSDSSDSSNSSDSSDS-SDSSDSSDSSNSSDSNDSSNSSDSS 795

Query: 367  AQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDS 426
              ++    +   D +  +               ++  +  NS   SN   +     + DS
Sbjct: 796  DSSNSSDSSNSSDSSDSS--------------DSSDSDSSNSSDSSNSSDSSDSSNSSDS 841

Query: 427  PSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLG 486
             S S   S GS S   +++   N S  + S  S++S+ S+  +  +N SS+S+ S D   
Sbjct: 842  -SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS-DSNESSNSSDSSD--- 896

Query: 487  FQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPH 546
                SS  +  +S D S SS    S NSS    +S+  D+      +NS  ++ S    +
Sbjct: 897  ----SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952

Query: 547  LDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT-AANSPFSSGSSVTSPSGTR 605
               ++        + +S   + + +     S S+     + +++S  SS SS +S S   
Sbjct: 953  SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012

Query: 606  FNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRS 665
             + S  +  +  +  S S+ +   + S  ++D   D    S   NSS S D    + S  
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSNSSDSSDSSDSSDSSD 1071

Query: 666  GSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTAN 725
             S      +   SS S  SS SS  S   +   S         D+S    S+ ++  + +
Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS--------DSSDSSDSSDSSDSSNS 1123

Query: 726  AHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTP 785
            +    + + S  + +      + ++E  DS  +            + ++ ++ +   +  
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183

Query: 786  ELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWLRSSFK 845
              +   + ++ S+D       SSDS  S +S+ S  S  S+  SDS      N   SS  
Sbjct: 1184 SDSSDSSDSSDSSD----SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN--ESSDS 1237

Query: 846  QAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSE 905
                      ++S  SD  + +DS+  S+ +      +G+     N   +   SE  DS 
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGN--NNGSDSDSDSEGSDSN 1295

Query: 906  AET 908
              T
Sbjct: 1296 HST 1298



 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 150/691 (21%), Positives = 269/691 (38%), Gaps = 30/691 (4%)

Query: 9    SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS 68
            S D +SS  S  SD+  + S+D  ++ SS SS ++  + S  + D    ++  S   ++ 
Sbjct: 571  SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630

Query: 69   LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT 128
              S D   KSD  SDS            N SD SD SD S S   +   + + S     +
Sbjct: 631  SDSSDSDSKSD-SSDS------------NSSDSSDNSDSSDSSNSS---NSSDSSDSSDS 674

Query: 129  AQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES 188
            +    +   +  S  + +  +  + ++ D+  S     S  +     + SD+  S+  +S
Sbjct: 675  SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734

Query: 189  KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS 248
                 SS  + ++++++      S  ++  +  + S  +  S  ++       S+  S S
Sbjct: 735  SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794

Query: 249  AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            +   +S D + + D    + SS ++    S      SNS + + + +S+ S DS+ SS  
Sbjct: 795  SDSSNSSDSSNSSDSSDSSDSSDSDSSNSS----DSSNSSDSSDSSNSSDSSDSSDSSDG 850

Query: 309  AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQ 368
            +        + S ++  S      N +D      S+  S +S +S   N +    S  + 
Sbjct: 851  SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910

Query: 369  TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS 428
            +S    +     +S +         +     + + N  +S   S+   +     + DS +
Sbjct: 911  SSDSSDSSNSSDSSES------SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964

Query: 429  GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQ 488
             S    S SS    S N   +     SS SS  S  SNS    ++ SS S+ S +     
Sbjct: 965  SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS--DSSDSSDSSDSSNSSDSS 1022

Query: 489  SVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLD 548
            + S    S +S D S SS    S +SS    +S+  DS      ++S  ++ S       
Sbjct: 1023 NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082

Query: 549  RNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNF 608
             ++        + +S      D+ +   S  +    D ++NS  SS SS +S S    N 
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD-SSNSSDSSDSSDSSDSSDSSNS 1141

Query: 609  SQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSF 668
            S  +  +  +  S S+ +   + S  ++D   D    S   +SS S D    + S   S 
Sbjct: 1142 SDSSDSSESSDSSDSSDSSDSSDSSDSSDSS-DSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200

Query: 669  RDGFEEVHGSSLSLVSSTSSVYSTPEEKCQS 699
                 +   SS S  SS SS  S   +   S
Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 154/699 (22%), Positives = 250/699 (35%), Gaps = 21/699 (3%)

Query: 9    SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS 68
            S D  SS SS  SD+ D  S+D  ++S S  S  +   SS+   D      K    + NS
Sbjct: 590  SSDSDSSDSSNSSDSSD--SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS 647

Query: 69   LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPS---DVSDESDKSTSGKKNPVISQTGSWRR 125
              S D+   SD  + S       S    + S   D S+ SD S S       S   S   
Sbjct: 648  SDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD-----SSNSSESS 702

Query: 126  GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
              +         +  S+ + +  +  +  +D +  S     S  +     S S     S 
Sbjct: 703  DSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762

Query: 186  DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALV 245
            + S     S S   + ++NS      S S+       +S  + +S S+       S +  
Sbjct: 763  NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822

Query: 246  SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNIS 305
            S  +   S    + N  D   +  S       S  R   SNS + + +  S++S DS+ S
Sbjct: 823  SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882

Query: 306  SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSS 365
            S S           S  +  S      N +D     +S + S +S +S   N +    SS
Sbjct: 883  SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942

Query: 366  PAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNS--VVISNPHATMTQQGN 423
             +  S           S           +     + + N  +S     S+  +  +   N
Sbjct: 943  DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002

Query: 424  LDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKD 483
                S S   S  S+S   S + D + S  +S  S +  +  +S +  ++ SS+S+ S D
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062

Query: 484  GLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSES 543
                   S    S +S D S SS    S NSS    +S   DS      ++S  ++ S  
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS------SDSSDSSDSSD 1116

Query: 544  DPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSG 603
                  ++        + +S      D+ +   S  +    D++ +S  SS SS +S S 
Sbjct: 1117 SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD-SSDSSDSSDSS 1175

Query: 604  TRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADG--QYDPYTDSRFRNSSMSLDEKSRT 661
               N S  +  +  +  S S+ +   + S  ++D     D    S   +SS S D    +
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235

Query: 662  MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSE 700
             S   S          SS S  SS S+  S  E   QS+
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274



 Score = 87.4 bits (215), Expect = 9e-17
 Identities = 148/695 (21%), Positives = 259/695 (37%), Gaps = 24/695 (3%)

Query: 11   DDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQT-DAEKHSQVERNSL 69
            +D S    G SD+ D+ S+D  N+S S  S  +  + S  + D  + D++     + +S 
Sbjct: 537  NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596

Query: 70   WSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTA 129
             S +    SD    S       S   ++ S  S ESD S S  K+       S       
Sbjct: 597  DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS-ESDSSDSDSKSDSSDSNSS------- 648

Query: 130  QVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESK 189
                +   +  S  + +  +  +  + D+  S     S  +S    S   +  S   +S 
Sbjct: 649  ---DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS 705

Query: 190  KPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSA 249
                S S   + ++NS      S +++  +  + S  +  S  ++       S+  S S+
Sbjct: 706  DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765

Query: 250  GRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSA 309
                S D + + D    + S+ ++    S    + S+S N + +  S+ S DS+ S+ S 
Sbjct: 766  DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825

Query: 310  GLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQT 369
                    + S ++  S      + +D +    SD+ S +S +S   + +    SS +  
Sbjct: 826  SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS-SNSSDSSDSSDSSNSSDSSDSSD 884

Query: 370  SLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSG 429
            S +         S           +     + + N  +S   SN         + +S   
Sbjct: 885  SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944

Query: 430  SGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQS 489
            S    S +SS   + +   N S  + S SS  S  SNS     + SS S+ S D      
Sbjct: 945  SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS-----SDSSDSSDSSDSSDSSD 999

Query: 490  VSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDR 549
             S+   S +S D S SS    S NSS    +S   DS      ++S  ++ S    +   
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059

Query: 550  NTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT-----AANSPFSSGSSVTSPSGT 604
            ++        + +S      D+ E   S  +    D+     +++S  SS SS +S S  
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119

Query: 605  RFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSR 664
              N S  +  +  +  S S+ +   + S  ++D   D    S   +SS S D    + S 
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS-DSSDSSDSSDSSDSSDSSDSSDSS 1178

Query: 665  SGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQS 699
            + S      +   SS S  SS SS  S   +   S
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 139/665 (20%), Positives = 254/665 (38%), Gaps = 12/665 (1%)

Query: 9    SWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNS 68
            S D  S  S   SD+ D+ S  D + S+S  S  N+ +S   N    +D+   S    +S
Sbjct: 619  SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678

Query: 69   LWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKS-TSGKKNPVISQTGSWRRGM 127
              S  D   S   SDS    +  +    + S  S +SD S +S   N   S + S     
Sbjct: 679  --SSSDSSNSSDSSDSS---DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD 733

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            ++    +   +  S  + +  +  +  + ++  S     S  +S    S      S+  +
Sbjct: 734  SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSS-ALVS 246
            S     SS  + +++++       S S+       +S  + +S S+       SS    S
Sbjct: 794  SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS 853

Query: 247  RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
             S+ R  S + + + D    + SS ++    S    + S+S + + +  S SS  SN S 
Sbjct: 854  DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913

Query: 307  KSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSP 366
             S         E S ++  S+     N +D      S N S +S +S   N +    S+ 
Sbjct: 914  SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973

Query: 367  AQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDS 426
            + +S    +     +S +         +     + + +  +S   S+   +     + DS
Sbjct: 974  SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033

Query: 427  PSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLG 486
               S    S  SS     +   N S  + S  S+ S+ S+  +  ++ SS S+ S D   
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS-DSSDSSESSDSSDSSN 1092

Query: 487  FQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPH 546
                S    S +S D S SS    S +SS    +S   DS      +NS  ++ S     
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152

Query: 547  LDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDT--AANSPFSSGSSVTSPSGT 604
               ++        + +S      D+     S  +    D+  +++S  SS SS +S S  
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212

Query: 605  RFNFSQLASPTTVTQMSLSNPTMLRTHSLSNAD--GQYDPYTDSRFRNSSMSLDEKSRTM 662
              + S  +  +  +  S SN +   + S  ++D     D    S   +S+   +++S + 
Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272

Query: 663  SRSGS 667
            S+SG+
Sbjct: 1273 SKSGN 1277



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 218/1048 (20%), Positives = 392/1048 (37%), Gaps = 83/1048 (7%)

Query: 12   DSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWS 71
            DSS+ S G  +  D+   DD ++S   +S       S++  D +   + H++V+      
Sbjct: 272  DSSNNSKG-QEGQDHGKEDDHDSSIGQNS------DSKEYYDPEGKEDPHNEVD------ 318

Query: 72   GDDVKKSDGGSDSGIKMEPGSKW------------RRNPSDVSDESDKSTSGK---KNPV 116
            GD   KS+  S +GI  + GS+             +R  + ++ ES+    GK   K   
Sbjct: 319  GDKTSKSEENS-AGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIE 377

Query: 117  ISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKG--RLSPKASQVK 174
            I    S  R +T +VG      +     G +   G  KT    V+ +G  + S   ++V 
Sbjct: 378  IKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVG 437

Query: 175  RSPSDA-----GRSSGDESKKPL----PSSSRTPTANANSFGFKKQSGSAAGLAMITASG 225
             S + +     G  S D   K +    P+SS     N ++      + S+ G A   +  
Sbjct: 438  HSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDE 497

Query: 226  VTVTSR-SATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSK 284
                   S + G     S   S +    S+ +G    DD   + S +             
Sbjct: 498  SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557

Query: 285  SNSRNGAGNRSSTSSIDSNISSKSAGLPVPKL-REPSKTALGSSLPGLVNQTDKEKGISS 343
            SNS + + +  S SS DSN SS S            S ++  S+     + +D      S
Sbjct: 558  SNSSDSSDSSDSDSS-DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616

Query: 344  DNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVA-----SPTLRRLFGGKPTKQVP 398
             + S +  +S K    +    S + +S    +   D +     S +         +    
Sbjct: 617  SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676

Query: 399  IATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPS 458
             +++ +  NS   S+   +     + DS   S   SS SS    S + D + S  + S  
Sbjct: 677  SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736

Query: 459  SAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGL 518
            S++S+ S+  +  +N+S SS  S D       S    S +S D S SS    S NSS   
Sbjct: 737  SSNSSDSSDSSDSSNSSDSSD-SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS 795

Query: 519  IASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSH 578
             +S+  DS      ++S  ++ S+S    D +         + +S      D+ +   S 
Sbjct: 796  DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS-------SDSSDSSNSSDSSD--SSD 846

Query: 579  SAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSL----- 633
            S+ G    ++N   SS SS +S S    N S  +  +   + S S+ +   ++S      
Sbjct: 847  SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906

Query: 634  --SNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYS 691
              SN+    D    S    SS S D  + + S + S      +   SS S  SS SS  S
Sbjct: 907  DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966

Query: 692  TPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAE 751
               +   S+        D+S    S+ ++  + +++   + + S  + +      + +++
Sbjct: 967  DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD 1026

Query: 752  QKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSV 811
              +S  ++   + +     +++  +  +   N+ + +   + ++ S+D       SSDS 
Sbjct: 1027 SSNS--SDSSDSSDSSDSSDSSDSSDSSDSSNSSD-SSDSSDSSDSSD-------SSDSS 1076

Query: 812  SSINSATSHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSL 871
             S +S+ S  S  S+  SDS      +    S   +     S  S SS S     +  S 
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136

Query: 872  PSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEAL 931
             SS     + S+ S+    +S S+        S++       N     +        ++ 
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS------DSS 1190

Query: 932  SSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQ 991
             S+   D    + +   S+       +D   S+S  S  S   ++ S S+    S   S 
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248

Query: 992  HSLNLTESTSLDMLLDDTGECSARKEGG 1019
             S +   S S D   D   E  ++ + G
Sbjct: 1249 SSDSSDSSDSSDSTSDSNDESDSQSKSG 1276



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 124/599 (20%), Positives = 225/599 (37%), Gaps = 14/599 (2%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            +S    SS SS  SD+ D  S+D  ++ SS SS +N+  S   N    +D+        N
Sbjct: 689  SSDSSDSSNSSESSDSSD--SSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS-------N 739

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S  S D    S+    S       S    + SD SD SD S S   N   + + S     
Sbjct: 740  SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            ++        +  S+ +       +  + D+  S     S  +S    S   +  S  D 
Sbjct: 800  SSD----SSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS 855

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKS-SALVS 246
            S +   S+S   + +++S      S S+       +S  + +S S+       S S+  S
Sbjct: 856  SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915

Query: 247  RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
             S+    S + + + D+   + SS ++    S    + S+S N + + +S+ S DSN S 
Sbjct: 916  DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD 975

Query: 307  KSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSP 366
             S         + S ++  S      N +D      S + S +S +S   + +    SS 
Sbjct: 976  SSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 1035

Query: 367  AQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDS 426
            +  S           S           +     ++  +  +    S+  +  +   N   
Sbjct: 1036 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095

Query: 427  PSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLG 486
             S S   S  S S   S + D + S  +S  S +  +  +S +  ++ SS S+ S D   
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155

Query: 487  FQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPH 546
                S    S +S D S SS    S +SS    +S   DS      ++S  ++ S     
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215

Query: 547  LDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTR 605
               ++        + +++     D+ +   S ++    D++ +S  +S S+  S S ++
Sbjct: 1216 SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 122/553 (22%), Positives = 213/553 (38%), Gaps = 32/553 (5%)

Query: 8    TSWDDSSSVSSGISDTIDNL-STDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVER 66
            +S    SS SS  SD+ D+  S+D  ++S+S  S  ++ +S   +    +D+   S    
Sbjct: 752  SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811

Query: 67   NSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRG 126
            +S  S  D   S   S+S    +  +    + SD SD SD S S   N   S   S    
Sbjct: 812  SSDSSDSDSSNSSDSSNSSDSSDSSNS--SDSSDSSDSSDGSDSDSSNRSDSSNSS---- 865

Query: 127  MTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGD 186
                       +  S  + +  +  +  ++++  S     S  +S    S S     S D
Sbjct: 866  ---------DSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916

Query: 187  ESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKS-SALV 245
             S     S S   + N+NS      S S+       +S  + +S S+       S S+  
Sbjct: 917  SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976

Query: 246  SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNIS 305
            S S+    S D + + D    + SS ++    S      SNS + + +  S++S DS+ S
Sbjct: 977  SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 1036

Query: 306  SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSS 365
            S S+        + S ++  S      N +D      S + S +S +S   + +    SS
Sbjct: 1037 SDSS--------DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088

Query: 366  PAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLD 425
             +  S          +S +         +     + + N  +S   S+   +     + D
Sbjct: 1089 DSSNSSDSSD-----SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143

Query: 426  SPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNA--SSSSAVSKD 483
            S   S    S  SS     +   + S  + S  S++S+ S+  +  +++  SS S+ S D
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203

Query: 484  GLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSES 543
                   S    S +S D S SS    S+ SS    +S   DS      ++S  ++ S S
Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263

Query: 544  DPHLDRNTLPKKG 556
            D + + ++  K G
Sbjct: 1264 DSNDESDSQSKSG 1276



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 113/527 (21%), Positives = 193/527 (36%), Gaps = 34/527 (6%)

Query: 6    NLTSWDDSSSVSSGISDTIDNLSTDDINTS----SSISSYANTPASSRKNLDVQTDAEKH 61
            N +   DSS  S     +  + S D  N+S    SS SS ++  + S  + D       +
Sbjct: 763  NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822

Query: 62   SQVERNSLWSGDDVKKSDG--GSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQ 119
            S    NS  S D    SD    SDS    +  S  R + S+ SD SD S S   +     
Sbjct: 823  SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882

Query: 120  TGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSD 179
            + S               +  S+ +          + D+  S     S  +S    S + 
Sbjct: 883  SDS-------------NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929

Query: 180  AGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIP 239
            +  S+  +S     SS  + ++N++       S +++  +   +S  + +S S+      
Sbjct: 930  SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS------ 983

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              S+  S S+    S D + + D    + SS ++    S      SNS + + +  S+ S
Sbjct: 984  -DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042

Query: 300  IDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPA 359
             DS+ SS S+        + S ++  S      + +D      S + S +S +S   N +
Sbjct: 1043 SDSSDSSDSS--------DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094

Query: 360  AQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMT 419
                SS +  S           S           +     ++  +  +    S+  +  +
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154

Query: 420  QQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSA 479
               +    S S   S  S S   S + D + S  +S  S +  +  +S +  ++ SS S+
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214

Query: 480  VSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDS 526
             S D       S    S ES D S SS    S NSS    +S   DS
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDS 1261



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 107/507 (21%), Positives = 196/507 (38%), Gaps = 33/507 (6%)

Query: 13   SSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWS- 71
            +SS SS  SD+ D+ ++ D + SS  S  +++ +S+R +    +D+   S    +S  S 
Sbjct: 822  NSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSD 881

Query: 72   ---GDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT 128
                ++   S   SDS    +  S    N SD SD S+ S S + +     + S     +
Sbjct: 882  SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS 941

Query: 129  AQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES 188
            +    +   +  S  + +  +  +  + D+  S+    S  +     S S     S D S
Sbjct: 942  SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001

Query: 189  KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS 248
                 S S   + ++NS      S S+       +S  + +S S+        S+  S S
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS-------DSSDSSDS 1054

Query: 249  AGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            +    S D + + D    + SS ++    S      SNS + + +  S+ S DS+ SS S
Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1114

Query: 309  AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQ 368
                       S ++  S+     + +D      S N S +S +S   + +    SS + 
Sbjct: 1115 -----------SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163

Query: 369  TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS 428
             S          +S +         +     + + +  +S   S+   +     + DS  
Sbjct: 1164 DSSD--------SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215

Query: 429  GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQ 488
             S    S  SS     N   + S  + S  S++S+ S+     +++S S++ S D    Q
Sbjct: 1216 SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD---SSDSSDSTSDSNDESDSQ 1272

Query: 489  SVSSLHTSCESIDISLSSGGVPSHNSS 515
            S S    +  S   S S G   +H++S
Sbjct: 1273 SKSGNGNNNGSDSDSDSEGSDSNHSTS 1299



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 2/97 (2%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            +S    SS SS  SD+ D+  + D N SS  S  +++  SS  N    +D+   S    +
Sbjct: 1207 SSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSS--NSSDSSDSSDSSDSTSD 1264

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDE 104
            S    D   KS  G+++G   +  S+   +    SD+
Sbjct: 1265 SNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 31.6 bits (70), Expect = 6.0
 Identities = 38/167 (22%), Positives = 64/167 (38%), Gaps = 15/167 (8%)

Query: 784 TPELNCKGNGTAQSADLRIRRQ----HSSDSVSSINSATSHSSVGSNIESDSKK---KKR 836
           TP++N K NGT ++       +     +SD   S N A      GS  + D +    K  
Sbjct: 214 TPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDS 273

Query: 837 KNWLRSSFKQAFGKKKS-PKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSN 895
            N  +    Q  GK+     S   +SD +E  D   P   + PHN   G     + S S 
Sbjct: 274 SNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYD---PEGKEDPHNEVDGD----KTSKSE 326

Query: 896 SLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLRE 942
              +   +      ++   +L  +E K  + R+   S  H + + ++
Sbjct: 327 ENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQD 373


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 74.3 bits (181), Expect = 8e-13
 Identities = 94/436 (21%), Positives = 185/436 (42%), Gaps = 22/436 (5%)

Query: 183 SSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSS 242
           ++ +E+     + S   ++ A++      S +++G++  T SG +VTS   +   I  +S
Sbjct: 22  TNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVS---IVTNS 78

Query: 243 ALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDS 302
              + S+G  ++ +   +     +++++ +     S    + +NS +   +  ++++ +S
Sbjct: 79  EFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNS 138

Query: 303 NISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGIS----SDNESVASCNSVKVNP 358
           + S+ S+G       + S T+  +S       +    G S    S++ +V+S  S   N 
Sbjct: 139 DSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNS 198

Query: 359 AAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATM 418
            +   SS A T+    ++     + T         T     +TA N ++S   S+   T 
Sbjct: 199 ESSTTSSGASTATNSESRTTSNGAGTATN--SESSTTSSGASTATNSESSTP-SSGAGTA 255

Query: 419 TQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSS 478
           T   +  + SG+G  ++  SS + S  +    +  +S+PSS  +  +NS +  T++ +++
Sbjct: 256 TNSESSTTSSGAGTATNSESSTV-SSGISTVTNSESSTPSSGANTATNSESSTTSSGANT 314

Query: 479 AVSKDGLGFQSVSSLHTSCESIDISL-------SSGGVPSHNSSTGLIASSKDDSLTPFV 531
           A + D     S +S  T+ ES   S        S     S  +ST   + S   S     
Sbjct: 315 ATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTST 374

Query: 532 RTNSVKTTLSE--SDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
            TNS  +T+S   S      ++    G      S+  T         ++S      + AN
Sbjct: 375 ATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGAS-TATNSESSTTSSGAN 433

Query: 590 SPFSSGSSVTSP-SGT 604
           +  +SGSSVTS  SGT
Sbjct: 434 TATNSGSSVTSAGSGT 449



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 107/511 (20%), Positives = 197/511 (38%), Gaps = 57/511 (11%)

Query: 23  TIDNLSTDDINTSSS-ISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGG 81
           T  N ++   NT SS ISS A+T  +S  ++         S     +  SG  V      
Sbjct: 22  TNSNETSTSANTGSSVISSGASTATNSGSSVT--------SSGVSTATISGSSV------ 67

Query: 82  SDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPS 141
           + +G+ +   S++    S +S  ++   S   + +   T S     T+    T   ++ S
Sbjct: 68  TSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNS-ESSTTSSGASTATNSESS 126

Query: 142 APAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTA 201
            P+    T       D+  +  G  +   S    + S+A  ++  ES     S + T T 
Sbjct: 127 TPSSGAST---ATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTT-SSGASTATN 182

Query: 202 NANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQ 261
           + +S    + S +    +  T+SG +  + S         S   S  AG  ++ + +   
Sbjct: 183 SESSTVSSRASTATNSESSTTSSGASTATNS--------ESRTTSNGAGTATNSESSTTS 234

Query: 262 DDGYLALSSRTNLQYRSLPRPSKS-NSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPS 320
                A +S ++         + S +S   +G  ++T+S  S +SS  + +   +   PS
Sbjct: 235 SGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPS 294

Query: 321 KTA-LGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPD 379
             A   ++       +      +SD+ + +S  S   N  +   SS A T+    +    
Sbjct: 295 SGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTS 354

Query: 380 VASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSS 439
             + T      G  T     +TA N ++S V S      T + +  S   S   +S SS+
Sbjct: 355 SGASTATN--SGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESST 412

Query: 440 PLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCES 499
                 V    S   +S SS  S+ +N+ T     +S S+V+  G G  +++ +HT+   
Sbjct: 413 ------VSSGASTATNSESSTTSSGANTAT-----NSGSSVTSAGSGTAALTGMHTT--- 458

Query: 500 IDISLSSGGVPSHNSSTGLIASSKDDSLTPF 530
                      SH++ST +  +    SL P+
Sbjct: 459 -----------SHSASTAVSEAKPGGSLVPW 478



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 92/428 (21%), Positives = 166/428 (38%), Gaps = 22/428 (5%)

Query: 416 ATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNAS 475
           AT + + +  + +GS V+SSG+S+   S +  +  S ++++  S  S  SN ++  TN  
Sbjct: 21  ATNSNETSTSANTGSSVISSGASTATNSGS-SVTSSGVSTATISGSSVTSNGVSIVTN-- 77

Query: 476 SSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP----FV 531
           S    +  G+   + S   T    I I+ +S    S  +S+G   ++  +S TP      
Sbjct: 78  SEFHTTSSGISTATNSEFSTVSSGISIATNS---ESSTTSSGASTATNSESSTPSSGAST 134

Query: 532 RTNSVKTTLS---ESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSA--GGLQDT 586
            TNS  +T S    +  + D +T   +    T +    T   A     S S+       T
Sbjct: 135 ATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRAST 194

Query: 587 AAN---SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPY 643
           A N   S  SSG+S  + S +R   +   + T     + S+     T+S S+        
Sbjct: 195 ATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSS-GAG 253

Query: 644 TDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRK 703
           T +   +S+ S    + T S S +   G   V  S  S  SS ++  +  E    S    
Sbjct: 254 TATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGAN 313

Query: 704 LRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKT 763
                D+S     A T   + ++   +    +  + +    S   TA    S       +
Sbjct: 314 TATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTS 373

Query: 764 IELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSV 823
                + +  +  A     +       G  TA +++       SS + ++ NS +S +S 
Sbjct: 374 TATNSESSTVSSGASTATTSESSTTSSGASTATNSE---SSTVSSGASTATNSESSTTSS 430

Query: 824 GSNIESDS 831
           G+N  ++S
Sbjct: 431 GANTATNS 438



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 80/401 (19%), Positives = 157/401 (39%), Gaps = 24/401 (5%)

Query: 6   NLTSWDDSSSVSSGISDTIDNLS----TDDINTSSSISSYANTPASS-RKNLDVQTDAEK 60
           ++TS   S++  SG S T + +S    ++   TSS IS+  N+  S+    + + T++E 
Sbjct: 51  SVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSES 110

Query: 61  HSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSK-------WRRNPSDVSDESDKSTSGKK 113
            +     S  +  +      G+ +    +  +           + S  S E+  +T+ + 
Sbjct: 111 STTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSES 170

Query: 114 NPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQV 173
           +   S   +     ++ V         S  +       T    +++ +  G  +  A+  
Sbjct: 171 STTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNG--AGTATNS 228

Query: 174 KRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMIT-ASGV-TVTSR 231
           + S + +G S+   S+   PSS      N+ S      +G+A      T +SG+ TVT+ 
Sbjct: 229 ESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNS 288

Query: 232 SATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPS----KSNS 287
            ++      ++A  S S+   S  + A N D    +  + T     S    S     +NS
Sbjct: 289 ESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNS 348

Query: 288 RNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGIS----S 343
            +   +  ++++ +S  S+ S+G       E S  + G+S       +    G S    S
Sbjct: 349 ESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNS 408

Query: 344 DNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPT 384
           ++ +V+S  S   N  +   SS A T+   G+      S T
Sbjct: 409 ESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGT 449



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 92/475 (19%), Positives = 170/475 (35%), Gaps = 45/475 (9%)

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKN----- 407
           S   N  +  +SS A T+   G+        T         +  V I T           
Sbjct: 28  STSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGI 87

Query: 408 SVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNS 467
           S   ++  +T++   ++ + S S   SSG+S+   S++         S+PSS  S  +NS
Sbjct: 88  STATNSEFSTVSSGISIATNSESSTTSSGASTATNSES---------STPSSGASTATNS 138

Query: 468 LTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSL 527
            +  T++ +S+A + D     S +S  T+ ES   + SSG   + NS +  ++S    + 
Sbjct: 139 DSSTTSSGASTATNSDSSTTSSEASTATNSES--STTSSGASTATNSESSTVSSRASTA- 195

Query: 528 TPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTA 587
                TNS  +T S              G      S+ RT  +      +  +      A
Sbjct: 196 -----TNSESSTTS-------------SGASTATNSESRTTSNGAGTATNSESSTTSSGA 237

Query: 588 ANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSR 647
           + +  S  S+ +S +GT  N     S ++ T       T   + ++S+        T + 
Sbjct: 238 STATNSESSTPSSGAGTATN-----SESSTTSSGAGTATNSESSTVSSGIS-----TVTN 287

Query: 648 FRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRE 707
             +S+ S    + T S S +   G      S  S  SS +S  +  E    S        
Sbjct: 288 SESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATN 347

Query: 708 LDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELL 767
            ++S     A T   + ++   +    +  + +  + S   TA   +S       +    
Sbjct: 348 SESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATN 407

Query: 768 KKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSS 822
            + +  +  A     +       G  TA ++   +    S  +  +    TSHS+
Sbjct: 408 SESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSA 462


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 152/824 (18%), Positives = 307/824 (37%), Gaps = 51/824 (6%)

Query: 14   SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
            ++ +S     +  +ST    T++  +  + T A+S    +  T +   S+    S    +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 74   DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
                S  GS++       S+     ++ S+ +  ST+  +  ++S TGS  R +T+  G 
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS-ERTITSTEGS 671

Query: 134  TMPRTKPSAPAGALKTPGTGKTDDAKV-SEKGRLSPKASQVKRSPSDAGR---SSGDESK 189
                   +     + T G+G T  +   SE  ++S   S+   + ++      +S   S+
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 190  KPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSA 249
                S+  + T  A++ G +  S S  G    TAS    TS   T+  I  S   ++ + 
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTAS---TTSSETTMASIMGSETTMASTI 788

Query: 250  GRKSS-MDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            G +++ +  A ++       +S T +   +    +  ++       +ST+  ++  ++ +
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTST 848

Query: 309  AGLPVPKLR-EPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
             G        E S+T   S+     ++T     I S+  + ++  S     + +   S  
Sbjct: 849  EGSETTTASTEGSETTTASTES---SETTTATTIGSETTTASTEGSETTTTSTE--GSET 903

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T+   G++   V++             +   A+ E  + + V +    T+T        
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSET 963

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            +    + S +++   + +     S   S  ++A    S + T  +  S ++ VS  G   
Sbjct: 964  TTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTET 1023

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
               S+  +   ++  + S         S     S++    T    T S  TT S +D  L
Sbjct: 1024 TITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTAD--L 1081

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFN 607
            +  T+   G   T T+     E    ++      G + T A++  S  ++V++ S     
Sbjct: 1082 ETTTVSTSGSG-TTTASTAGSETTTVYIT-----GSKTTTASTEGSEATTVSTTSSETTT 1135

Query: 608  FSQLASPTTVTQMSLSNPTMLRT----HSLSNADGQY--DPYTDSRFRNSSMSLDEKSRT 661
             S   S  T    ++S  T + T     + S+A G       T+     ++ +   ++ T
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTT 1195

Query: 662  MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQ 721
             S +GS         GS  +   +T S  STP                A  E  +A    
Sbjct: 1196 ASTAGS-ETTTASTSGSETNTACTTGSETSTPSS--------------AGSETNTAFIIG 1240

Query: 722  LTANAHLVAAFEQSLGNMT-IRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAING 780
              +     A+ E +  ++T     ++++TA    +    +  T  +L K   A   +I  
Sbjct: 1241 SESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK---ATDVSIQP 1297

Query: 781  VINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVG 824
            + NTP    +  GT  +A   +      D  +   SA SH+  G
Sbjct: 1298 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTA---SAASHTVPG 1338



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 137/699 (19%), Positives = 257/699 (36%), Gaps = 46/699 (6%)

Query: 14  SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
           ++V+          ST    T++ +   + T  +S    +  T +   SQ    S+   +
Sbjct: 5   TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE 64

Query: 74  DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
               S  GS++      GS      S    E+  ST+G +   +S TG+    ++A    
Sbjct: 65  ITTTSTAGSENTTVSSAGSG-TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 134 TMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGR------SSGDE 187
           T   +  S+      T G+  T  + V  +   +  A     + S  G       ++G E
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE 183

Query: 188 SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV-TVTSRSATLGKIPKSSALVS 246
           +  P  + S T T   ++ G +  + S  G    TAS   + T+ ++T+G    S     
Sbjct: 184 TITPSTAGSETTT--VSTAGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKV 237

Query: 247 RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
            +AG ++++  A ++        S TN  +    + + +++       +ST+  +  ++S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 307 KSAGLPVPKLR---EPSKTALGSSLPGLV----NQTDKEKGISSDNESVASCNSVKVNPA 359
                         E +K +  SS    V    ++T +   + S+  +V++  S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS--ETTT 355

Query: 360 AQPVSSPAQTSLQPGAKYPDVA---SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHA 416
           A  + S   T    G++    +   S T      G     V    +E    S+  S    
Sbjct: 356 ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTT 415

Query: 417 TMTQQGNLDSPSGS---GVLSSGSSSPLYSKNVDLNQSPLASSPSS----AHSAPSNSLT 469
           T T+   + + S +      +S   S +   +   +++  AS+  S      +A S + T
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475

Query: 470 WGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP 529
             T  S ++  S  GL   +V ++ +   +     S     S   S     S++    T 
Sbjct: 476 AYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTT 535

Query: 530 FVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
              T S  TT+S +   L+  T   +G      S++ T         + S  G   TAA+
Sbjct: 536 VSTTGSETTTVSTTG--LETTTTSTEG------SEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 590 SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFR 649
           +  S  ++V++        S   S TT    + S  T   T S           T+    
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS----TEGSET 643

Query: 650 NSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSS 688
            +  + D ++  +S +GS R       GS  + VS+T S
Sbjct: 644 TTVSTTDSETTMVSTTGSERT-ITSTEGSETTTVSATGS 681



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 116/635 (18%), Positives = 230/635 (36%), Gaps = 60/635 (9%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++VS+  S+TI           +S +    T  +S +  +  T + + S+    
Sbjct: 817  TTASETTTVSTAGSETI----------PASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S  S +    +  GS++      GS+     ++ S+ +  ST G +   +S TGS     
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            + +   T   T  S     L T  T  ++   VS +G  +   + +  S +    ++G E
Sbjct: 927  STEGSET---TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM-GSETTTASTAGSE 982

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247
            +     + S T TA+          GS       T S  T  S + T       + + S 
Sbjct: 983  TTTVSTAGSETTTASI--------EGSETTTVSSTGSETTTVSTTGT------ETTITST 1028

Query: 248  SAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSK 307
                 +++  A ++        S T            + S  G+   + +++     ++ 
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETT-----------TTSTEGSETTTVSTTGSETTTAS 1077

Query: 308  SAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
            +A L    +         +S  G    T    G  +   S     +  V+  +   ++ +
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAS 1137

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T  +    +  V+  T     G + T     A +E    S   S      T      + 
Sbjct: 1138 TTGSEMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTEGSETTTASTAGSETTTA 1196

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            S +G  ++ +S+     N         S+PSSA S  + +   G+ ++ +S  S +    
Sbjct: 1197 STAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTA- 1255

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
             S++   T+  SI  S ++    + +S+T ++  + D S+ P   T    T  + +    
Sbjct: 1256 TSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA 1315

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGG--LQDTAANSPFSSGSSVTSPSGTR 605
              +     G+ +T ++             SH+  G  L  +   +     SS TS  G R
Sbjct: 1316 SSSVTMAPGMDFTASA------------ASHTVPGIVLNTSGLGTSTMGASSTTSAHGVR 1363

Query: 606  FNFSQLASPTTVT-----QMSLSNPTMLRTHSLSN 635
                    PT+ T      +S+   T+  +H+ +N
Sbjct: 1364 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTN 1398



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 150/814 (18%), Positives = 301/814 (36%), Gaps = 77/814 (9%)

Query: 6   NLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVE 65
           N T+  +++  S+  S+T   +ST    T+++ ++ + T A+S    ++ T     S+  
Sbjct: 127 NSTTSSETTVTSTAGSETT-TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185

Query: 66  RNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR 125
             S    +    S  GS++      GS+     +  S+ +  ST G +   +S  GS   
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 126 GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
             TA    T   T+ S          T  T+D+K +       + +    + S+   +S 
Sbjct: 246 VSTAGSETTAASTEDS-------ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 186 DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALV 245
             S+  + S+    T   ++   +  +  AAG   I AS  TV S + T+      +   
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS--TVGSETTTVSTTGSETTTA 356

Query: 246 SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI-DSNI 304
           S   G ++S D     +      S+  +    +    S++ + +  G+ ++T SI DS  
Sbjct: 357 S-IMGSETSTDSTTGSET--TTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 305 S------SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKE------KGISSDNESVASCN 352
           +      S+   +        + +  GS +  + + +D E      +G  +   + A   
Sbjct: 414 TTTCTEGSEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT------KQVPIATAENMK 406
           +          ++ + T L+    +   +  T     G + T       ++   + E  +
Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 407 NSVVISNPHATMT-------------------------QQGNLDSPSGSGVL---SSGSS 438
           N+ V +    T T                          +   DS  GSG     ++GS 
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 439 SPLYS--KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTS 496
           +   S   + +   S   S  +SA +  S + T  T +S ++  S +G    +VS+  + 
Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 497 CESIDISLSSGGVPS-HNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKK 555
              +  + S   + S   S T  ++++  ++      + +   +++ S+      T  + 
Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSET 712

Query: 556 GLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPT 615
               T  S++ T         + S  G + T A++  S  +S ++        S  +S T
Sbjct: 713 TTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772

Query: 616 TVTQMSLSNPTML-----RTHSLSNADGQYDP-YTDSRFRNSSMSLDEKSRTMSRSGSFR 669
           T+  +  S  TM       T  +S A  +    +T++     + +   ++ T+S +GS  
Sbjct: 773 TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-- 830

Query: 670 DGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLV 729
              E +  S+    S T++  ST   +  +   +      AS E     T     +    
Sbjct: 831 ---ETIPASTAG--SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 730 AAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKT 763
           A+ E S    T    S T TA  + SE+  +  T
Sbjct: 886 ASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 919



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 136/748 (18%), Positives = 273/748 (36%), Gaps = 64/748 (8%)

Query: 4   PRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQ 63
           P   ++    ++++S I      +ST     ++  ++ + T  +S    +  T +   S+
Sbjct: 293 PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSE 352

Query: 64  VERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
               S+   +    S  GS++      GS+     ++ S+ +  ST+G +   +S T S 
Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS- 411

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRS 183
               T   G  M     +A +  +    T  T+ ++++         +    S +    +
Sbjct: 412 ETTTTCTEGSEM-----TAVSTTVFETTTASTEGSEIT--------IASTSDSETTTAST 458

Query: 184 SGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSA 243
            G E+     + S T TA         ++ +A+   + T +  T+ S + T       + 
Sbjct: 459 EGSETTTVTTAGSETKTAYTTG----SETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 244 LVSRSAGRKS--SMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
            VS +    +  S +G++N        S  T +    L   + S   +     S+T +  
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTG-SETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 302 SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
           +  S++ +G           T + ++       ++     ++D+E+ ++  +      A 
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTA------DSENTTASTADSETTSASTTGSETTTAS 627

Query: 362 PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQ 421
             SS   T+   G++   V++             +  I + E  + + V +    T    
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV-- 685

Query: 422 GNLDSPSGSG---VLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASS 476
               S  GSG   V  +GS +   S   +     S   S  ++A    S + T  T  S 
Sbjct: 686 ----STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 477 SSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSV 536
           ++  S +  G ++ S+  T  E+   S +S    S  +   ++ S    + T    T  V
Sbjct: 742 TTTASTE--GSETTSASTTGSETTTASTTS----SETTMASIMGSETTMASTIGSETTKV 795

Query: 537 KTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 596
            T  S+       N+  +  +  T  S+  T   A       S  G + T   S   S +
Sbjct: 796 STASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 597 SVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLD 656
           +  S  G+    +   S  T T  ++ + T     + ++ +G     T +    ++ +  
Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGSET-----TTASTEGSETTTTSTEGSETTTAST 908

Query: 657 EKSR--TMSRSGS-----FRDGFE----EVHGSSLSLVSSTSS--VYSTPEEKCQSEIRK 703
           E S   T+S +GS       +G E       GS L+ VS+T S  +  + E    + +  
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968

Query: 704 LRRELDASQEKVSALTTQLTANAHLVAA 731
           +  E   +    S  TT  TA +    A
Sbjct: 969 MGSETTTASTAGSETTTVSTAGSETTTA 996



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 113/591 (19%), Positives = 219/591 (37%), Gaps = 42/591 (7%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++ +S         ST+   T+++ +  + T  ++    +  T + + S+    
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT 896

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S    +    S  GS+       GS+     ++ S+ +  ST G +   +S TGS    +
Sbjct: 897  STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            +A+   T   T  +       T  T  ++   VS  G  +  AS ++ S +    S+G E
Sbjct: 957  SAEGSET---TTVTTMGSETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVSSTGSE 1012

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAG---LAMITASGVTVT-----SRSATLGKIP 239
            +     S++ T T   ++ G +  + + AG    A+ T    T T     S + T+    
Sbjct: 1013 T--TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              +   S +    +++  + +         S T   Y +  + + +++        ST+S
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 300  IDSNISSKSAGLPVPKLREPSKT---------ALGSSLPGLVNQTDKEKGISSDNESVAS 350
             ++  +S +           S+T         A  SS  G    T   +G  +   S A 
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 351  CNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVV 410
              +   + A    ++ A TS           S T      G  T    I  +E+   S  
Sbjct: 1191 SETTTASTAGSETTT-ASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTA 1249

Query: 411  ISNPHATMTQQGNLD----SPSGSGVLSSGSSSPLY--SKNVDLNQSPLASSPSSAHSAP 464
               P AT            + SG+   S+  SS  +  +K  D++  P+ ++P S     
Sbjct: 1250 SLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309

Query: 465  SNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKD 524
               LT     +SSS     G+ F + ++ HT      I L++ G+ +         S+  
Sbjct: 1310 GTRLT-----ASSSVTMAPGMDFTASAASHT---VPGIVLNTSGLGTSTMGASSTTSAHG 1361

Query: 525  DSLTPFVRTNSVKTTLSESDP-HLDRNTLPKKGLRYTPTSQLRTQEDAKEW 574
               T         +T  E+ P  +  NT+    + +TPT+ ++     + W
Sbjct: 1362 VRTTTGSTREPTSSTFQETGPVSMGTNTV---SMSHTPTNVIKPSGYLQPW 1409



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 137/738 (18%), Positives = 260/738 (35%), Gaps = 89/738 (12%)

Query: 5    RNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQV 64
            R +TS + S + +   + +   +ST+   T++   + + T   S    +  T + + S++
Sbjct: 663  RTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWR 124
               S+   +    S  GS++      GS+     +  S+ +  ST+  +  + S  GS  
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS-E 781

Query: 125  RGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSS 184
              M + +G     TK S  +  + T  T  ++    S              S +    ++
Sbjct: 782  TTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS-----------TTASETTTVSTA 828

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
            G E+     + S T T  +   G +  + S  G    TAS  +  + +AT      ++A 
Sbjct: 829  GSETIPASTAGSETTTTTSTE-GSETTTASTEGSETTTASTESSETTTATTIGSETTTAS 887

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSN- 303
               S    +S +G++                  +    S+  + +  G+ ++T+S + + 
Sbjct: 888  TEGSETTTTSTEGSETT---------------TASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 304  -ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQP 362
              ++ + G  +  +       +  S  G    T    G  +   S A   +  V+ A   
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA--- 989

Query: 363  VSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQG 422
              S   T+   G++   V+S        G  T  V     E    S   S    T+T  G
Sbjct: 990  -GSETTTASIEGSETTTVSST-------GSETTTVSTTGTETTITSTEGSET-TTVTTAG 1040

Query: 423  NLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSK 482
            +      + V ++GS +   S           S  ++  +  S + T  T    ++ VS 
Sbjct: 1041 S----ETTAVYTTGSETTTTSTE--------GSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 483  DGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSE 542
             G G  + S+  +   ++ I+ S     S   S     S+     T    T S  TT+  
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV-- 1146

Query: 543  SDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPS 602
                            +T  S+  T         + SA G + T  ++  S  ++ ++  
Sbjct: 1147 ----------------FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 603  GTRFNFSQLASPTTVTQMSLSNP-TMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRT 661
                  S   S TT    S S   T   T S ++        T++ F   S S      T
Sbjct: 1191 SETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSES------T 1244

Query: 662  MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVS----- 716
            ++ + S       + GS  + VS T+S  +       S    L +  D S + ++     
Sbjct: 1245 IASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304

Query: 717  ---ALTTQLTANAHLVAA 731
                  T+LTA++ +  A
Sbjct: 1305 GTRTTGTRLTASSSVTMA 1322



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 123/739 (16%), Positives = 258/739 (34%), Gaps = 77/739 (10%)

Query: 173 VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRS 232
           +K S +    ++G E+  P P+ S+T   + +  G +  + S AG    T S        
Sbjct: 30  IKASETTTASTAGSETTTPSPTGSQTTIVSIS--GSEITTTSTAGSENTTVSS---AGSG 84

Query: 233 ATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAG 292
            T   +  S   VS +    +++     +     A+ S T     +    S++   + AG
Sbjct: 85  TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTT---SSETTVTSTAG 141

Query: 293 NRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCN 352
           + ++T S        + G               +S  G    T    G  +   S A   
Sbjct: 142 SETTTVS--------TVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412
           +  V+ A    ++ + T  +        +  T     G + TK   ++TA    +   +S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK---VSTA---GSETTVS 247

Query: 413 NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGT 472
              +  T     DS + +       ++   +   +       ++ S+  S P+ + T G+
Sbjct: 248 TAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE------TTAASTTGSEPTMASTMGS 301

Query: 473 NASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVR 532
             + +S +  +       + + T+   +    ++G      S+ G               
Sbjct: 302 ETTMASTIGPE------TTKVSTASSEVTTVFAAGSETIRASTVG-------------SE 342

Query: 533 TNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPF 592
           T +V TT SE+       T    G      S+  T         + S  G + T A++  
Sbjct: 343 TTTVSTTGSET------TTASIMG------SETSTDSTTGSETTTASTEGSETTTASTEG 390

Query: 593 SSGSSVTSPSGTRFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSNADGQYDPYTDSR 647
           S  ++V++        S   S TT T     +M+  + T+  T + S    +    + S 
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 648 FRNSSMSLD-EKSRTMSRSGS-----FRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEI 701
              ++ S +  ++ T++ +GS     +  G E    S+  L ++T     +      +E 
Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG 510

Query: 702 RKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDS---ELN 758
            +    + A+  +++ ++T+ + N  +     ++    T  L++ T + E  +       
Sbjct: 511 SE-TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569

Query: 759 ELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSAT 818
               T +  +     A +       T       N TA +AD       ++ S ++  S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629

Query: 819 SHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLP 878
           S  +  ++ E             ++     G   S ++ +S    E  T S+  S   + 
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTG---SERTITSTEGSETTTVSATGSETTVS 686

Query: 879 HNGSTGSTPLLRNSHSNSL 897
             GS  +T  +  S +  +
Sbjct: 687 TEGSGTTTVSITGSETTKV 705


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 152/824 (18%), Positives = 306/824 (37%), Gaps = 51/824 (6%)

Query: 14   SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
            ++ +S     +  +ST    T++  +  + T A+S    +  T +   S+    S    +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 74   DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
                S  GS++       S+     ++ S+ +  ST+  +  ++S TGS  R +T+  G 
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS-ERTITSTEGS 671

Query: 134  TMPRTKPSAPAGALKTPGTGKTDDAKV-SEKGRLSPKASQVKRSPSDAGR---SSGDESK 189
                   +     + T G+G T  +   SE  ++S   S+   + ++      +S   S+
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 190  KPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSA 249
                S+  + T  A++ G +  S S  G    TAS    TS   T+  I  S   ++ + 
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTAS---TTSSETTMASIMGSETTMASTI 788

Query: 250  GRKSS-MDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            G +++ +  A ++       +S T +   +    +  ++       +ST+  ++  ++ +
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTST 848

Query: 309  AGLPVPKLR-EPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
             G        E S+T   S+     ++T     I S+  + ++  S     + +   S  
Sbjct: 849  EGSETTTASTEGSETTTASTES---SETTTATTIGSETTTASTEGSETTTTSTE--GSET 903

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T+   G++   V++             +   A+ E  + + V +    T+T        
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSET 963

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            +    + S +++   + +     S   S  ++A    S + T  +  S ++ VS  G   
Sbjct: 964  TTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTET 1023

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
               S+  +   ++  + S         S     S++    T    T S  TT S +D  L
Sbjct: 1024 TITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTAD--L 1081

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFN 607
            +  T+   G   T T+     E    ++      G + T A++  S  ++V++ S     
Sbjct: 1082 ETTTVSTSGSG-TTTASTAGSETTTVYIT-----GSKTTTASTEGSEATTVSTTSSETTT 1135

Query: 608  FSQLASPTTVTQMSLSNPTMLRT----HSLSNADGQY--DPYTDSRFRNSSMSLDEKSRT 661
             S   S  T    ++S  T + T     + S+A G       T+     ++ +   ++ T
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTT 1195

Query: 662  MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQ 721
             S +GS         GS  +   +T S  STP                A  E  +A    
Sbjct: 1196 ASTAGS-ETTTASTSGSETNTACTTGSETSTPSS--------------AGSETNTAFIIG 1240

Query: 722  LTANAHLVAAFEQSLGNMT-IRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAING 780
                    A+ E +  ++T     ++++TA    +    +  T  +L K   A   +I  
Sbjct: 1241 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK---ATDVSIQP 1297

Query: 781  VINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVG 824
            + NTP    +  GT  +A   +      D  +   SA SH+  G
Sbjct: 1298 ITNTPMSGTRTTGTRPTASSSVTMAPGMDFTA---SAASHTVPG 1338



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 117/635 (18%), Positives = 230/635 (36%), Gaps = 60/635 (9%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++VS+  S+TI           +S +    T  +S +  +  T + + S+    
Sbjct: 817  TTASETTTVSTAGSETI----------PASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S  S +    +  GS++      GS+     ++ S+ +  ST G +   +S TGS     
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            + +   T   T  S     L T  T  ++   VS +G  +   + +  S +    ++G E
Sbjct: 927  STEGSET---TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM-GSETTTASTAGSE 982

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247
            +     + S T TA+          GS       T S  T  S + T       + + S 
Sbjct: 983  TTTVSTAGSETTTASI--------EGSETTTVSSTGSETTTVSTTGT------ETTITST 1028

Query: 248  SAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSK 307
                 +++  A ++        S T            + S  G+   + +++     ++ 
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETT-----------TTSTEGSETTTVSTTGSETTTAS 1077

Query: 308  SAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
            +A L    +         +S  G    T    G  +   S     +  V+  +   ++ +
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAS 1137

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T  +    +  V+  T     G + T     A +E    S   S      T      + 
Sbjct: 1138 TTGSEMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTEGSETTTASTAGSETTTA 1196

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            S +G  ++ +S+     N         S+PSSA S  + +   G+  + +S  S +    
Sbjct: 1197 STAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTA- 1255

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
             S++   T+  SI  S ++    + +S+T ++  + D S+ P   T    T  + + P  
Sbjct: 1256 TSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTA 1315

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGG--LQDTAANSPFSSGSSVTSPSGTR 605
              +     G+ +T ++             SH+  G  L  +   +     SS TS  G R
Sbjct: 1316 SSSVTMAPGMDFTASA------------ASHTVPGIVLNTSGLGTSTMGASSTTSAHGVR 1363

Query: 606  FNFSQLASPTTVT-----QMSLSNPTMLRTHSLSN 635
                    PT+ T      +S+   T+  +H+ +N
Sbjct: 1364 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTN 1398



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 137/699 (19%), Positives = 257/699 (36%), Gaps = 46/699 (6%)

Query: 14  SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
           ++V+          ST    T++ +   + T  +S    +  T +   SQ    S+   +
Sbjct: 5   TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE 64

Query: 74  DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
               S  GS++      GS      S    E+  ST+G +   +S TG+    ++A    
Sbjct: 65  ITTTSTAGSENTTVSSAGSG-TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 134 TMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGR------SSGDE 187
           T   +  S+      T G+  T  + V  +   +  A     + S  G       ++G E
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE 183

Query: 188 SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV-TVTSRSATLGKIPKSSALVS 246
           +  P  + S T T   ++ G +  + S  G    TAS   + T+ ++T+G    S     
Sbjct: 184 TITPSTAGSETTT--VSTAGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKV 237

Query: 247 RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
            +AG ++++  A ++        S TN  +    + + +++       +ST+  +  ++S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 307 KSAGLPVPKLR---EPSKTALGSSLPGLV----NQTDKEKGISSDNESVASCNSVKVNPA 359
                         E +K +  SS    V    ++T +   + S+  +V++  S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS--ETTT 355

Query: 360 AQPVSSPAQTSLQPGAKYPDVA---SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHA 416
           A  + S   T    G++    +   S T      G     V    +E    S+  S    
Sbjct: 356 ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTT 415

Query: 417 TMTQQGNLDSPSGS---GVLSSGSSSPLYSKNVDLNQSPLASSPSS----AHSAPSNSLT 469
           T T+   + + S +      +S   S +   +   +++  AS+  S      +A S + T
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475

Query: 470 WGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP 529
             T  S ++  S  GL   +V ++ +   +     S     S   S     S++    T 
Sbjct: 476 AYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTT 535

Query: 530 FVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
              T S  TT+S +   L+  T   +G      S++ T         + S  G   TAA+
Sbjct: 536 VSTTGSETTTVSTTG--LETTTTSTEG------SEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 590 SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFR 649
           +  S  ++V++        S   S TT    + S  T   T S           T+    
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS----TEGSET 643

Query: 650 NSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSS 688
            +  + D ++  +S +GS R       GS  + VS+T S
Sbjct: 644 TTVSTTDSETTMVSTTGSERT-ITSTEGSETTTVSATGS 681



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 150/814 (18%), Positives = 301/814 (36%), Gaps = 77/814 (9%)

Query: 6   NLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVE 65
           N T+  +++  S+  S+T   +ST    T+++ ++ + T A+S    ++ T     S+  
Sbjct: 127 NSTTSSETTVTSTAGSETT-TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185

Query: 66  RNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR 125
             S    +    S  GS++      GS+     +  S+ +  ST G +   +S  GS   
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 126 GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
             TA    T   T+ S          T  T+D+K +       + +    + S+   +S 
Sbjct: 246 VSTAGSETTAASTEDS-------ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 186 DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALV 245
             S+  + S+    T   ++   +  +  AAG   I AS  TV S + T+      +   
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS--TVGSETTTVSTTGSETTTA 356

Query: 246 SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI-DSNI 304
           S   G ++S D     +      S+  +    +    S++ + +  G+ ++T SI DS  
Sbjct: 357 S-IMGSETSTDSTTGSET--TTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 305 S------SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKE------KGISSDNESVASCN 352
           +      S+   +        + +  GS +  + + +D E      +G  +   + A   
Sbjct: 414 TTTCTEGSEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT------KQVPIATAENMK 406
           +          ++ + T L+    +   +  T     G + T       ++   + E  +
Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 407 NSVVISNPHATMT-------------------------QQGNLDSPSGSGVL---SSGSS 438
           N+ V +    T T                          +   DS  GSG     ++GS 
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 439 SPLYS--KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTS 496
           +   S   + +   S   S  +SA +  S + T  T +S ++  S +G    +VS+  + 
Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 497 CESIDISLSSGGVPS-HNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKK 555
              +  + S   + S   S T  ++++  ++      + +   +++ S+      T  + 
Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSET 712

Query: 556 GLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPT 615
               T  S++ T         + S  G + T A++  S  +S ++        S  +S T
Sbjct: 713 TTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772

Query: 616 TVTQMSLSNPTML-----RTHSLSNADGQYDP-YTDSRFRNSSMSLDEKSRTMSRSGSFR 669
           T+  +  S  TM       T  +S A  +    +T++     + +   ++ T+S +GS  
Sbjct: 773 TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-- 830

Query: 670 DGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLV 729
              E +  S+    S T++  ST   +  +   +      AS E     T     +    
Sbjct: 831 ---ETIPASTAG--SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 730 AAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKT 763
           A+ E S    T    S T TA  + SE+  +  T
Sbjct: 886 ASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 919



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 136/748 (18%), Positives = 273/748 (36%), Gaps = 64/748 (8%)

Query: 4   PRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQ 63
           P   ++    ++++S I      +ST     ++  ++ + T  +S    +  T +   S+
Sbjct: 293 PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSE 352

Query: 64  VERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
               S+   +    S  GS++      GS+     ++ S+ +  ST+G +   +S T S 
Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS- 411

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRS 183
               T   G  M     +A +  +    T  T+ ++++         +    S +    +
Sbjct: 412 ETTTTCTEGSEM-----TAVSTTVFETTTASTEGSEIT--------IASTSDSETTTAST 458

Query: 184 SGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSA 243
            G E+     + S T TA         ++ +A+   + T +  T+ S + T       + 
Sbjct: 459 EGSETTTVTTAGSETKTAYTTG----SETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 244 LVSRSAGRKS--SMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
            VS +    +  S +G++N        S  T +    L   + S   +     S+T +  
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTG-SETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 302 SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
           +  S++ +G           T + ++       ++     ++D+E+ ++  +      A 
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTA------DSENTTASTADSETTSASTTGSETTTAS 627

Query: 362 PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQ 421
             SS   T+   G++   V++             +  I + E  + + V +    T    
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV-- 685

Query: 422 GNLDSPSGSG---VLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASS 476
               S  GSG   V  +GS +   S   +     S   S  ++A    S + T  T  S 
Sbjct: 686 ----STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 477 SSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSV 536
           ++  S +  G ++ S+  T  E+   S +S    S  +   ++ S    + T    T  V
Sbjct: 742 TTTASTE--GSETTSASTTGSETTTASTTS----SETTMASIMGSETTMASTIGSETTKV 795

Query: 537 KTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 596
            T  S+       N+  +  +  T  S+  T   A       S  G + T   S   S +
Sbjct: 796 STASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 597 SVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLD 656
           +  S  G+    +   S  T T  ++ + T     + ++ +G     T +    ++ +  
Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGSET-----TTASTEGSETTTTSTEGSETTTAST 908

Query: 657 EKSR--TMSRSGS-----FRDGFE----EVHGSSLSLVSSTSS--VYSTPEEKCQSEIRK 703
           E S   T+S +GS       +G E       GS L+ VS+T S  +  + E    + +  
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968

Query: 704 LRRELDASQEKVSALTTQLTANAHLVAA 731
           +  E   +    S  TT  TA +    A
Sbjct: 969 MGSETTTASTAGSETTTVSTAGSETTTA 996



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 114/592 (19%), Positives = 223/592 (37%), Gaps = 44/592 (7%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++ +S         ST+   T+++ +  + T  ++    +  T + + S+    
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT 896

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S    +    S  GS+       GS+     ++ S+ +  ST G +   +S TGS    +
Sbjct: 897  STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            +A+   T   T  +       T  T  ++   VS  G  +  AS ++ S +    S+G E
Sbjct: 957  SAEGSET---TTVTTMGSETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVSSTGSE 1012

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAG---LAMITASGVTVT-----SRSATLGKIP 239
            +     S++ T T   ++ G +  + + AG    A+ T    T T     S + T+    
Sbjct: 1013 T--TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              +   S +    +++  + +         S T   Y +  + + +++        ST+S
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 300  IDSNISSKSAGLPVPKLREPSKT---------ALGSSLPGLVNQTDKEKGISSDNESVAS 350
             ++  +S +           S+T         A  SS  G    T   +G  +   S A 
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 351  CNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVV 410
              +   + A    ++ A TS           S T      G  T    I  +E    S  
Sbjct: 1191 SETTTASTAGSETTT-ASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTA 1249

Query: 411  ISNPHATMTQQGNLD----SPSGSGVLSSGSSSPLY--SKNVDLNQSPLASSPSSAHSAP 464
               P AT            + SG+   S+  SS  +  +K  D++  P+ ++P       
Sbjct: 1250 SLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPM------ 1303

Query: 465  SNSLTWGTNASSSSAVS-KDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSK 523
            S + T GT  ++SS+V+   G+ F + ++ HT      I L++ G+ +         S+ 
Sbjct: 1304 SGTRTTGTRPTASSSVTMAPGMDFTASAASHT---VPGIVLNTSGLGTSTMGASSTTSAH 1360

Query: 524  DDSLTPFVRTNSVKTTLSESDP-HLDRNTLPKKGLRYTPTSQLRTQEDAKEW 574
                T         +T  E+ P  +  NT+    + +TPT+ ++     + W
Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTV---SMSHTPTNVIKPSGYLQPW 1409



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 123/638 (19%), Positives = 232/638 (36%), Gaps = 62/638 (9%)

Query: 5    RNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQV 64
            R +TS + S + +   + +   +ST+   T++   + + T   S    +  T + + S++
Sbjct: 663  RTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWR 124
               S+   +    S  GS++      GS+     +  S+ +  ST+  +  + S  GS  
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS-E 781

Query: 125  RGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSS 184
              M + +G     TK S  +  + T  T  ++    S              S +    ++
Sbjct: 782  TTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS-----------TTASETTTVSTA 828

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
            G E+     + S T T  +   G +  + S  G    TAS  +  + +AT      ++A 
Sbjct: 829  GSETIPASTAGSETTTTTSTE-GSETTTASTEGSETTTASTESSETTTATTIGSETTTAS 887

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSN- 303
               S    +S +G++                  +    S+  + +  G+ ++T+S + + 
Sbjct: 888  TEGSETTTTSTEGSETT---------------TASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 304  -ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQP 362
              ++ + G  +  +       +  S  G    T    G  +   S A   +  V+ A   
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA--- 989

Query: 363  VSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQG 422
              S   T+   G++   V+S        G  T  V     E    S   S    T+T  G
Sbjct: 990  -GSETTTASIEGSETTTVSST-------GSETTTVSTTGTETTITSTEGSET-TTVTTAG 1040

Query: 423  NLDSPSGSGVLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAV 480
            +      + V ++GS +   S   +     S   S  ++A +A   + T  T+ S ++  
Sbjct: 1041 S----ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTA 1096

Query: 481  SKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTL 540
            S  G    +V    +   +     S     S  SS    AS+    +T    T S  TT+
Sbjct: 1097 STAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTV 1156

Query: 541  SESDPHLDRNTLPKKGLRYTPT--SQLRTQEDAKEWLRSHSAGGLQDTAA-------NSP 591
            S        ++        T T  S+  T   A     + S  G + T A       N+ 
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216

Query: 592  FSSGSSVTSPS--GTRFNFS-QLASPTTVTQMSLSNPT 626
             ++GS  ++PS  G+  N +  + S TT+   +   PT
Sbjct: 1217 CTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPT 1254



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 123/739 (16%), Positives = 258/739 (34%), Gaps = 77/739 (10%)

Query: 173 VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRS 232
           +K S +    ++G E+  P P+ S+T   + +  G +  + S AG    T S        
Sbjct: 30  IKASETTTASTAGSETTTPSPTGSQTTIVSIS--GSEITTTSTAGSENTTVSS---AGSG 84

Query: 233 ATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAG 292
            T   +  S   VS +    +++     +     A+ S T     +    S++   + AG
Sbjct: 85  TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTT---SSETTVTSTAG 141

Query: 293 NRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCN 352
           + ++T S        + G               +S  G    T    G  +   S A   
Sbjct: 142 SETTTVS--------TVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412
           +  V+ A    ++ + T  +        +  T     G + TK   ++TA    +   +S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK---VSTA---GSETTVS 247

Query: 413 NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGT 472
              +  T     DS + +       ++   +   +       ++ S+  S P+ + T G+
Sbjct: 248 TAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE------TTAASTTGSEPTMASTMGS 301

Query: 473 NASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVR 532
             + +S +  +       + + T+   +    ++G      S+ G               
Sbjct: 302 ETTMASTIGPE------TTKVSTASSEVTTVFAAGSETIRASTVG-------------SE 342

Query: 533 TNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPF 592
           T +V TT SE+       T    G      S+  T         + S  G + T A++  
Sbjct: 343 TTTVSTTGSET------TTASIMG------SETSTDSTTGSETTTASTEGSETTTASTEG 390

Query: 593 SSGSSVTSPSGTRFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSNADGQYDPYTDSR 647
           S  ++V++        S   S TT T     +M+  + T+  T + S    +    + S 
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 648 FRNSSMSLD-EKSRTMSRSGS-----FRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEI 701
              ++ S +  ++ T++ +GS     +  G E    S+  L ++T     +      +E 
Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG 510

Query: 702 RKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDS---ELN 758
            +    + A+  +++ ++T+ + N  +     ++    T  L++ T + E  +       
Sbjct: 511 SE-TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569

Query: 759 ELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSAT 818
               T +  +     A +       T       N TA +AD       ++ S ++  S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629

Query: 819 SHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLP 878
           S  +  ++ E             ++     G   S ++ +S    E  T S+  S   + 
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTG---SERTITSTEGSETTTVSATGSETTVS 686

Query: 879 HNGSTGSTPLLRNSHSNSL 897
             GS  +T  +  S +  +
Sbjct: 687 TEGSGTTTVSITGSETTKV 705


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 152/824 (18%), Positives = 306/824 (37%), Gaps = 51/824 (6%)

Query: 14   SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
            ++ +S     +  +ST    T++  +  + T A+S    +  T +   S+    S    +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 74   DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
                S  GS++       S+     ++ S+ +  ST+  +  ++S TGS  R +T+  G 
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS-ERTITSTEGS 671

Query: 134  TMPRTKPSAPAGALKTPGTGKTDDAKV-SEKGRLSPKASQVKRSPSDAGR---SSGDESK 189
                   +     + T G+G T  +   SE  ++S   S+   + ++      +S   S+
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 190  KPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSA 249
                S+  + T  A++ G +  S S  G    TAS    TS   T+  I  S   ++ + 
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTAS---TTSSETTMASIMGSETTMASTI 788

Query: 250  GRKSS-MDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            G +++ +  A ++       +S T +   +    +  ++       +ST+  ++  ++ +
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTST 848

Query: 309  AGLPVPKLR-EPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
             G        E S+T   S+     ++T     I S+  + ++  S     + +   S  
Sbjct: 849  EGSETTTASTEGSETTTASTES---SETTTATTIGSETTTASTEGSETTTTSTE--GSET 903

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T+   G++   V++             +   A+ E  + + V +    T+T        
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSET 963

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            +    + S +++   + +     S   S  ++A    S + T  +  S ++ VS  G   
Sbjct: 964  TTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTET 1023

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
               S+  +   ++  + S         S     S++    T    T S  TT S +D  L
Sbjct: 1024 TITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTAD--L 1081

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFN 607
            +  T+   G   T T+     E    ++      G + T A++  S  ++V++ S     
Sbjct: 1082 ETTTVSTSGSG-TTTASTAGSETTTVYIT-----GSKTTTASTEGSEATTVSTTSSETTT 1135

Query: 608  FSQLASPTTVTQMSLSNPTMLRT----HSLSNADGQY--DPYTDSRFRNSSMSLDEKSRT 661
             S   S  T    ++S  T + T     + S+A G       T+     ++ +   ++ T
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTT 1195

Query: 662  MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQ 721
             S +GS         GS  +   +T S  STP                A  E  +A    
Sbjct: 1196 ASTAGS-ETTTASTSGSETNTACTTGSETSTPSS--------------AGSETNTAFIIG 1240

Query: 722  LTANAHLVAAFEQSLGNMT-IRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAING 780
                    A+ E +  ++T     ++++TA    +    +  T  +L K   A   +I  
Sbjct: 1241 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK---ATDVSIQP 1297

Query: 781  VINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVG 824
            + NTP    +  GT  +A   +      D  +   SA SH+  G
Sbjct: 1298 ITNTPMSGTRTTGTRPTASSSVTMAPGMDFTA---SAASHTVPG 1338



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 117/635 (18%), Positives = 230/635 (36%), Gaps = 60/635 (9%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++VS+  S+TI           +S +    T  +S +  +  T + + S+    
Sbjct: 817  TTASETTTVSTAGSETI----------PASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S  S +    +  GS++      GS+     ++ S+ +  ST G +   +S TGS     
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            + +   T   T  S     L T  T  ++   VS +G  +   + +  S +    ++G E
Sbjct: 927  STEGSET---TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM-GSETTTASTAGSE 982

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247
            +     + S T TA+          GS       T S  T  S + T       + + S 
Sbjct: 983  TTTVSTAGSETTTASI--------EGSETTTVSSTGSETTTVSTTGT------ETTITST 1028

Query: 248  SAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSK 307
                 +++  A ++        S T            + S  G+   + +++     ++ 
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETT-----------TTSTEGSETTTVSTTGSETTTAS 1077

Query: 308  SAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
            +A L    +         +S  G    T    G  +   S     +  V+  +   ++ +
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAS 1137

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T  +    +  V+  T     G + T     A +E    S   S      T      + 
Sbjct: 1138 TTGSEMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTEGSETTTASTAGSETTTA 1196

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            S +G  ++ +S+     N         S+PSSA S  + +   G+  + +S  S +    
Sbjct: 1197 STAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTA- 1255

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
             S++   T+  SI  S ++    + +S+T ++  + D S+ P   T    T  + + P  
Sbjct: 1256 TSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTA 1315

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGG--LQDTAANSPFSSGSSVTSPSGTR 605
              +     G+ +T ++             SH+  G  L  +   +     SS TS  G R
Sbjct: 1316 SSSVTMAPGMDFTASA------------ASHTVPGIVLNTSGLGTSTMGASSTTSAHGVR 1363

Query: 606  FNFSQLASPTTVT-----QMSLSNPTMLRTHSLSN 635
                    PT+ T      +S+   T+  +H+ +N
Sbjct: 1364 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTN 1398



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 137/699 (19%), Positives = 257/699 (36%), Gaps = 46/699 (6%)

Query: 14  SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
           ++V+          ST    T++ +   + T  +S    +  T +   SQ    S+   +
Sbjct: 5   TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE 64

Query: 74  DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
               S  GS++      GS      S    E+  ST+G +   +S TG+    ++A    
Sbjct: 65  ITTTSTAGSENTTVSSAGSG-TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 134 TMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGR------SSGDE 187
           T   +  S+      T G+  T  + V  +   +  A     + S  G       ++G E
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE 183

Query: 188 SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV-TVTSRSATLGKIPKSSALVS 246
           +  P  + S T T   ++ G +  + S  G    TAS   + T+ ++T+G    S     
Sbjct: 184 TITPSTAGSETTT--VSTAGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKV 237

Query: 247 RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
            +AG ++++  A ++        S TN  +    + + +++       +ST+  +  ++S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 307 KSAGLPVPKLR---EPSKTALGSSLPGLV----NQTDKEKGISSDNESVASCNSVKVNPA 359
                         E +K +  SS    V    ++T +   + S+  +V++  S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS--ETTT 355

Query: 360 AQPVSSPAQTSLQPGAKYPDVA---SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHA 416
           A  + S   T    G++    +   S T      G     V    +E    S+  S    
Sbjct: 356 ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTT 415

Query: 417 TMTQQGNLDSPSGS---GVLSSGSSSPLYSKNVDLNQSPLASSPSS----AHSAPSNSLT 469
           T T+   + + S +      +S   S +   +   +++  AS+  S      +A S + T
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475

Query: 470 WGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP 529
             T  S ++  S  GL   +V ++ +   +     S     S   S     S++    T 
Sbjct: 476 AYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTT 535

Query: 530 FVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
              T S  TT+S +   L+  T   +G      S++ T         + S  G   TAA+
Sbjct: 536 VSTTGSETTTVSTTG--LETTTTSTEG------SEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 590 SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFR 649
           +  S  ++V++        S   S TT    + S  T   T S           T+    
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS----TEGSET 643

Query: 650 NSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSS 688
            +  + D ++  +S +GS R       GS  + VS+T S
Sbjct: 644 TTVSTTDSETTMVSTTGSERT-ITSTEGSETTTVSATGS 681



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 150/814 (18%), Positives = 301/814 (36%), Gaps = 77/814 (9%)

Query: 6   NLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVE 65
           N T+  +++  S+  S+T   +ST    T+++ ++ + T A+S    ++ T     S+  
Sbjct: 127 NSTTSSETTVTSTAGSETT-TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185

Query: 66  RNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR 125
             S    +    S  GS++      GS+     +  S+ +  ST G +   +S  GS   
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 126 GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
             TA    T   T+ S          T  T+D+K +       + +    + S+   +S 
Sbjct: 246 VSTAGSETTAASTEDS-------ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 186 DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALV 245
             S+  + S+    T   ++   +  +  AAG   I AS  TV S + T+      +   
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS--TVGSETTTVSTTGSETTTA 356

Query: 246 SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI-DSNI 304
           S   G ++S D     +      S+  +    +    S++ + +  G+ ++T SI DS  
Sbjct: 357 S-IMGSETSTDSTTGSET--TTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 305 S------SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKE------KGISSDNESVASCN 352
           +      S+   +        + +  GS +  + + +D E      +G  +   + A   
Sbjct: 414 TTTCTEGSEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT------KQVPIATAENMK 406
           +          ++ + T L+    +   +  T     G + T       ++   + E  +
Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 407 NSVVISNPHATMT-------------------------QQGNLDSPSGSGVL---SSGSS 438
           N+ V +    T T                          +   DS  GSG     ++GS 
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 439 SPLYS--KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTS 496
           +   S   + +   S   S  +SA +  S + T  T +S ++  S +G    +VS+  + 
Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 497 CESIDISLSSGGVPS-HNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKK 555
              +  + S   + S   S T  ++++  ++      + +   +++ S+      T  + 
Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSET 712

Query: 556 GLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPT 615
               T  S++ T         + S  G + T A++  S  +S ++        S  +S T
Sbjct: 713 TTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772

Query: 616 TVTQMSLSNPTML-----RTHSLSNADGQYDP-YTDSRFRNSSMSLDEKSRTMSRSGSFR 669
           T+  +  S  TM       T  +S A  +    +T++     + +   ++ T+S +GS  
Sbjct: 773 TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-- 830

Query: 670 DGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLV 729
              E +  S+    S T++  ST   +  +   +      AS E     T     +    
Sbjct: 831 ---ETIPASTAG--SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 730 AAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKT 763
           A+ E S    T    S T TA  + SE+  +  T
Sbjct: 886 ASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 919



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 136/748 (18%), Positives = 273/748 (36%), Gaps = 64/748 (8%)

Query: 4   PRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQ 63
           P   ++    ++++S I      +ST     ++  ++ + T  +S    +  T +   S+
Sbjct: 293 PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSE 352

Query: 64  VERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
               S+   +    S  GS++      GS+     ++ S+ +  ST+G +   +S T S 
Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS- 411

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRS 183
               T   G  M     +A +  +    T  T+ ++++         +    S +    +
Sbjct: 412 ETTTTCTEGSEM-----TAVSTTVFETTTASTEGSEIT--------IASTSDSETTTAST 458

Query: 184 SGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSA 243
            G E+     + S T TA         ++ +A+   + T +  T+ S + T       + 
Sbjct: 459 EGSETTTVTTAGSETKTAYTTG----SETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 244 LVSRSAGRKS--SMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
            VS +    +  S +G++N        S  T +    L   + S   +     S+T +  
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTG-SETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 302 SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
           +  S++ +G           T + ++       ++     ++D+E+ ++  +      A 
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTA------DSENTTASTADSETTSASTTGSETTTAS 627

Query: 362 PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQ 421
             SS   T+   G++   V++             +  I + E  + + V +    T    
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV-- 685

Query: 422 GNLDSPSGSG---VLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASS 476
               S  GSG   V  +GS +   S   +     S   S  ++A    S + T  T  S 
Sbjct: 686 ----STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 477 SSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSV 536
           ++  S +  G ++ S+  T  E+   S +S    S  +   ++ S    + T    T  V
Sbjct: 742 TTTASTE--GSETTSASTTGSETTTASTTS----SETTMASIMGSETTMASTIGSETTKV 795

Query: 537 KTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 596
            T  S+       N+  +  +  T  S+  T   A       S  G + T   S   S +
Sbjct: 796 STASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 597 SVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLD 656
           +  S  G+    +   S  T T  ++ + T     + ++ +G     T +    ++ +  
Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGSET-----TTASTEGSETTTTSTEGSETTTAST 908

Query: 657 EKSR--TMSRSGS-----FRDGFE----EVHGSSLSLVSSTSS--VYSTPEEKCQSEIRK 703
           E S   T+S +GS       +G E       GS L+ VS+T S  +  + E    + +  
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968

Query: 704 LRRELDASQEKVSALTTQLTANAHLVAA 731
           +  E   +    S  TT  TA +    A
Sbjct: 969 MGSETTTASTAGSETTTVSTAGSETTTA 996



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 114/592 (19%), Positives = 223/592 (37%), Gaps = 44/592 (7%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++ +S         ST+   T+++ +  + T  ++    +  T + + S+    
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT 896

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S    +    S  GS+       GS+     ++ S+ +  ST G +   +S TGS    +
Sbjct: 897  STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            +A+   T   T  +       T  T  ++   VS  G  +  AS ++ S +    S+G E
Sbjct: 957  SAEGSET---TTVTTMGSETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVSSTGSE 1012

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAG---LAMITASGVTVT-----SRSATLGKIP 239
            +     S++ T T   ++ G +  + + AG    A+ T    T T     S + T+    
Sbjct: 1013 T--TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              +   S +    +++  + +         S T   Y +  + + +++        ST+S
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 300  IDSNISSKSAGLPVPKLREPSKT---------ALGSSLPGLVNQTDKEKGISSDNESVAS 350
             ++  +S +           S+T         A  SS  G    T   +G  +   S A 
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 351  CNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVV 410
              +   + A    ++ A TS           S T      G  T    I  +E    S  
Sbjct: 1191 SETTTASTAGSETTT-ASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTA 1249

Query: 411  ISNPHATMTQQGNLD----SPSGSGVLSSGSSSPLY--SKNVDLNQSPLASSPSSAHSAP 464
               P AT            + SG+   S+  SS  +  +K  D++  P+ ++P       
Sbjct: 1250 SLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPM------ 1303

Query: 465  SNSLTWGTNASSSSAVS-KDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSK 523
            S + T GT  ++SS+V+   G+ F + ++ HT      I L++ G+ +         S+ 
Sbjct: 1304 SGTRTTGTRPTASSSVTMAPGMDFTASAASHT---VPGIVLNTSGLGTSTMGASSTTSAH 1360

Query: 524  DDSLTPFVRTNSVKTTLSESDP-HLDRNTLPKKGLRYTPTSQLRTQEDAKEW 574
                T         +T  E+ P  +  NT+    + +TPT+ ++     + W
Sbjct: 1361 GVRTTTGSTREPTSSTFQETGPVSMGTNTV---SMSHTPTNVIKPSGYLQPW 1409



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 123/638 (19%), Positives = 232/638 (36%), Gaps = 62/638 (9%)

Query: 5    RNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQV 64
            R +TS + S + +   + +   +ST+   T++   + + T   S    +  T + + S++
Sbjct: 663  RTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWR 124
               S+   +    S  GS++      GS+     +  S+ +  ST+  +  + S  GS  
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS-E 781

Query: 125  RGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSS 184
              M + +G     TK S  +  + T  T  ++    S              S +    ++
Sbjct: 782  TTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS-----------TTASETTTVSTA 828

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
            G E+     + S T T  +   G +  + S  G    TAS  +  + +AT      ++A 
Sbjct: 829  GSETIPASTAGSETTTTTSTE-GSETTTASTEGSETTTASTESSETTTATTIGSETTTAS 887

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSN- 303
               S    +S +G++                  +    S+  + +  G+ ++T+S + + 
Sbjct: 888  TEGSETTTTSTEGSETT---------------TASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 304  -ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQP 362
              ++ + G  +  +       +  S  G    T    G  +   S A   +  V+ A   
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA--- 989

Query: 363  VSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQG 422
              S   T+   G++   V+S        G  T  V     E    S   S    T+T  G
Sbjct: 990  -GSETTTASIEGSETTTVSST-------GSETTTVSTTGTETTITSTEGSET-TTVTTAG 1040

Query: 423  NLDSPSGSGVLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAV 480
            +      + V ++GS +   S   +     S   S  ++A +A   + T  T+ S ++  
Sbjct: 1041 S----ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTA 1096

Query: 481  SKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTL 540
            S  G    +V    +   +     S     S  SS    AS+    +T    T S  TT+
Sbjct: 1097 STAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTV 1156

Query: 541  SESDPHLDRNTLPKKGLRYTPT--SQLRTQEDAKEWLRSHSAGGLQDTAA-------NSP 591
            S        ++        T T  S+  T   A     + S  G + T A       N+ 
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216

Query: 592  FSSGSSVTSPS--GTRFNFS-QLASPTTVTQMSLSNPT 626
             ++GS  ++PS  G+  N +  + S TT+   +   PT
Sbjct: 1217 CTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPT 1254



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 123/739 (16%), Positives = 258/739 (34%), Gaps = 77/739 (10%)

Query: 173 VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRS 232
           +K S +    ++G E+  P P+ S+T   + +  G +  + S AG    T S        
Sbjct: 30  IKASETTTASTAGSETTTPSPTGSQTTIVSIS--GSEITTTSTAGSENTTVSS---AGSG 84

Query: 233 ATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAG 292
            T   +  S   VS +    +++     +     A+ S T     +    S++   + AG
Sbjct: 85  TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTT---SSETTVTSTAG 141

Query: 293 NRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCN 352
           + ++T S        + G               +S  G    T    G  +   S A   
Sbjct: 142 SETTTVS--------TVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412
           +  V+ A    ++ + T  +        +  T     G + TK   ++TA    +   +S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK---VSTA---GSETTVS 247

Query: 413 NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGT 472
              +  T     DS + +       ++   +   +       ++ S+  S P+ + T G+
Sbjct: 248 TAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE------TTAASTTGSEPTMASTMGS 301

Query: 473 NASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVR 532
             + +S +  +       + + T+   +    ++G      S+ G               
Sbjct: 302 ETTMASTIGPE------TTKVSTASSEVTTVFAAGSETIRASTVG-------------SE 342

Query: 533 TNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPF 592
           T +V TT SE+       T    G      S+  T         + S  G + T A++  
Sbjct: 343 TTTVSTTGSET------TTASIMG------SETSTDSTTGSETTTASTEGSETTTASTEG 390

Query: 593 SSGSSVTSPSGTRFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSNADGQYDPYTDSR 647
           S  ++V++        S   S TT T     +M+  + T+  T + S    +    + S 
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 648 FRNSSMSLD-EKSRTMSRSGS-----FRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEI 701
              ++ S +  ++ T++ +GS     +  G E    S+  L ++T     +      +E 
Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG 510

Query: 702 RKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDS---ELN 758
            +    + A+  +++ ++T+ + N  +     ++    T  L++ T + E  +       
Sbjct: 511 SE-TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569

Query: 759 ELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSAT 818
               T +  +     A +       T       N TA +AD       ++ S ++  S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629

Query: 819 SHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLP 878
           S  +  ++ E             ++     G   S ++ +S    E  T S+  S   + 
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTG---SERTITSTEGSETTTVSATGSETTVS 686

Query: 879 HNGSTGSTPLLRNSHSNSL 897
             GS  +T  +  S +  +
Sbjct: 687 TEGSGTTTVSITGSETTKV 705


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 152/824 (18%), Positives = 307/824 (37%), Gaps = 51/824 (6%)

Query: 14   SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
            ++ +S     +  +ST    T++  +  + T A+S    +  T +   S+    S    +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 74   DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
                S  GS++       S+     ++ S+ +  ST+  +  ++S TGS  R +T+  G 
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS-ERTITSTEGS 671

Query: 134  TMPRTKPSAPAGALKTPGTGKTDDAKV-SEKGRLSPKASQVKRSPSDAGR---SSGDESK 189
                   +     + T G+G T  +   SE  ++S   S+   + ++      +S   S+
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 190  KPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSA 249
                S+  + T  A++ G +  S S  G    TAS    TS   T+  I  S   ++ + 
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTAS---TTSSETTMASIMGSETTMASTI 788

Query: 250  GRKSS-MDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            G +++ +  A ++       +S T +   +    +  ++       +ST+  ++  ++ +
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTST 848

Query: 309  AGLPVPKLR-EPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
             G        E S+T   S+     ++T     I S+  + ++  S     + +   S  
Sbjct: 849  EGSETTTASTEGSETTTASTES---SETTTATTIGSETTTASTEGSETTTTSTE--GSET 903

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T+   G++   V++             +   A+ E  + + V +    T+T        
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSET 963

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            +    + S +++   + +     S   S  ++A    S + T  +  S ++ VS  G   
Sbjct: 964  TTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTET 1023

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
               S+  +   ++  + S         S     S++    T    T S  TT S +D  L
Sbjct: 1024 TITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTAD--L 1081

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFN 607
            +  T+   G   T T+     E    ++      G + T A++  S  ++V++ S     
Sbjct: 1082 ETTTVSTSGSG-TTTASTAGSETTTVYIT-----GSKTTTASTEGSEATTVSTTSSETTT 1135

Query: 608  FSQLASPTTVTQMSLSNPTMLRT----HSLSNADGQY--DPYTDSRFRNSSMSLDEKSRT 661
             S   S  T    ++S  T + T     + S+A G       T+     ++ +   ++ T
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTT 1195

Query: 662  MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQ 721
             S +GS         GS  +   +T S  STP                A  E  +A    
Sbjct: 1196 ASTAGS-ETTTASTSGSETNTACTTGSETSTPSS--------------AGSETNTAFIIG 1240

Query: 722  LTANAHLVAAFEQSLGNMT-IRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAING 780
              +     A+ E +  ++T     ++++TA    +    +  T  +L K   A   +I  
Sbjct: 1241 SESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK---ATDVSIQP 1297

Query: 781  VINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVG 824
            + NTP    +  GT  +A   +      D  +   SA SH+  G
Sbjct: 1298 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTA---SAASHTVPG 1338



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 137/699 (19%), Positives = 257/699 (36%), Gaps = 46/699 (6%)

Query: 14  SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
           ++V+          ST    T++ +   + T  +S    +  T +   SQ    S+   +
Sbjct: 5   TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE 64

Query: 74  DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
               S  GS++      GS      S    E+  ST+G +   +S TG+    ++A    
Sbjct: 65  ITTTSTAGSENTTVSSAGSG-TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 134 TMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGR------SSGDE 187
           T   +  S+      T G+  T  + V  +   +  A     + S  G       ++G E
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE 183

Query: 188 SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV-TVTSRSATLGKIPKSSALVS 246
           +  P  + S T T   ++ G +  + S  G    TAS   + T+ ++T+G    S     
Sbjct: 184 TITPSTAGSETTT--VSTAGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKV 237

Query: 247 RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
            +AG ++++  A ++        S TN  +    + + +++       +ST+  +  ++S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 307 KSAGLPVPKLR---EPSKTALGSSLPGLV----NQTDKEKGISSDNESVASCNSVKVNPA 359
                         E +K +  SS    V    ++T +   + S+  +V++  S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS--ETTT 355

Query: 360 AQPVSSPAQTSLQPGAKYPDVA---SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHA 416
           A  + S   T    G++    +   S T      G     V    +E    S+  S    
Sbjct: 356 ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTT 415

Query: 417 TMTQQGNLDSPSGS---GVLSSGSSSPLYSKNVDLNQSPLASSPSS----AHSAPSNSLT 469
           T T+   + + S +      +S   S +   +   +++  AS+  S      +A S + T
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475

Query: 470 WGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP 529
             T  S ++  S  GL   +V ++ +   +     S     S   S     S++    T 
Sbjct: 476 AYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTT 535

Query: 530 FVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
              T S  TT+S +   L+  T   +G      S++ T         + S  G   TAA+
Sbjct: 536 VSTTGSETTTVSTTG--LETTTTSTEG------SEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 590 SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFR 649
           +  S  ++V++        S   S TT    + S  T   T S           T+    
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS----TEGSET 643

Query: 650 NSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSS 688
            +  + D ++  +S +GS R       GS  + VS+T S
Sbjct: 644 TTVSTTDSETTMVSTTGSERT-ITSTEGSETTTVSATGS 681



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 116/635 (18%), Positives = 230/635 (36%), Gaps = 60/635 (9%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++VS+  S+TI           +S +    T  +S +  +  T + + S+    
Sbjct: 817  TTASETTTVSTAGSETI----------PASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S  S +    +  GS++      GS+     ++ S+ +  ST G +   +S TGS     
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            + +   T   T  S     L T  T  ++   VS +G  +   + +  S +    ++G E
Sbjct: 927  STEGSET---TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM-GSETTTASTAGSE 982

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247
            +     + S T TA+          GS       T S  T  S + T       + + S 
Sbjct: 983  TTTVSTAGSETTTASI--------EGSETTTVSSTGSETTTVSTTGT------ETTITST 1028

Query: 248  SAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSK 307
                 +++  A ++        S T            + S  G+   + +++     ++ 
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETT-----------TTSTEGSETTTVSTTGSETTTAS 1077

Query: 308  SAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
            +A L    +         +S  G    T    G  +   S     +  V+  +   ++ +
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAS 1137

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T  +    +  V+  T     G + T     A +E    S   S      T      + 
Sbjct: 1138 TTGSEMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTEGSETTTASTAGSETTTA 1196

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            S +G  ++ +S+     N         S+PSSA S  + +   G+ ++ +S  S +    
Sbjct: 1197 STAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTA- 1255

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
             S++   T+  SI  S ++    + +S+T ++  + D S+ P   T    T  + +    
Sbjct: 1256 TSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA 1315

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGG--LQDTAANSPFSSGSSVTSPSGTR 605
              +     G+ +T ++             SH+  G  L  +   +     SS TS  G R
Sbjct: 1316 SSSVTMAPGMDFTASA------------ASHTVPGIVLNTSGLGTSTMGASSTTSAHGVR 1363

Query: 606  FNFSQLASPTTVT-----QMSLSNPTMLRTHSLSN 635
                    PT+ T      +S+   T+  +H+ +N
Sbjct: 1364 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTN 1398



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 150/814 (18%), Positives = 301/814 (36%), Gaps = 77/814 (9%)

Query: 6   NLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVE 65
           N T+  +++  S+  S+T   +ST    T+++ ++ + T A+S    ++ T     S+  
Sbjct: 127 NSTTSSETTVTSTAGSETT-TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185

Query: 66  RNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR 125
             S    +    S  GS++      GS+     +  S+ +  ST G +   +S  GS   
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 126 GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
             TA    T   T+ S          T  T+D+K +       + +    + S+   +S 
Sbjct: 246 VSTAGSETTAASTEDS-------ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 186 DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALV 245
             S+  + S+    T   ++   +  +  AAG   I AS  TV S + T+      +   
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS--TVGSETTTVSTTGSETTTA 356

Query: 246 SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI-DSNI 304
           S   G ++S D     +      S+  +    +    S++ + +  G+ ++T SI DS  
Sbjct: 357 S-IMGSETSTDSTTGSET--TTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 305 S------SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKE------KGISSDNESVASCN 352
           +      S+   +        + +  GS +  + + +D E      +G  +   + A   
Sbjct: 414 TTTCTEGSEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT------KQVPIATAENMK 406
           +          ++ + T L+    +   +  T     G + T       ++   + E  +
Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 407 NSVVISNPHATMT-------------------------QQGNLDSPSGSGVL---SSGSS 438
           N+ V +    T T                          +   DS  GSG     ++GS 
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 439 SPLYS--KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTS 496
           +   S   + +   S   S  +SA +  S + T  T +S ++  S +G    +VS+  + 
Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 497 CESIDISLSSGGVPS-HNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKK 555
              +  + S   + S   S T  ++++  ++      + +   +++ S+      T  + 
Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSET 712

Query: 556 GLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPT 615
               T  S++ T         + S  G + T A++  S  +S ++        S  +S T
Sbjct: 713 TTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772

Query: 616 TVTQMSLSNPTML-----RTHSLSNADGQYDP-YTDSRFRNSSMSLDEKSRTMSRSGSFR 669
           T+  +  S  TM       T  +S A  +    +T++     + +   ++ T+S +GS  
Sbjct: 773 TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-- 830

Query: 670 DGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLV 729
              E +  S+    S T++  ST   +  +   +      AS E     T     +    
Sbjct: 831 ---ETIPASTAG--SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 730 AAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKT 763
           A+ E S    T    S T TA  + SE+  +  T
Sbjct: 886 ASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 919



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 136/748 (18%), Positives = 273/748 (36%), Gaps = 64/748 (8%)

Query: 4   PRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQ 63
           P   ++    ++++S I      +ST     ++  ++ + T  +S    +  T +   S+
Sbjct: 293 PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSE 352

Query: 64  VERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
               S+   +    S  GS++      GS+     ++ S+ +  ST+G +   +S T S 
Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS- 411

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRS 183
               T   G  M     +A +  +    T  T+ ++++         +    S +    +
Sbjct: 412 ETTTTCTEGSEM-----TAVSTTVFETTTASTEGSEIT--------IASTSDSETTTAST 458

Query: 184 SGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSA 243
            G E+     + S T TA         ++ +A+   + T +  T+ S + T       + 
Sbjct: 459 EGSETTTVTTAGSETKTAYTTG----SETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 244 LVSRSAGRKS--SMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
            VS +    +  S +G++N        S  T +    L   + S   +     S+T +  
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTG-SETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 302 SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
           +  S++ +G           T + ++       ++     ++D+E+ ++  +      A 
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTA------DSENTTASTADSETTSASTTGSETTTAS 627

Query: 362 PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQ 421
             SS   T+   G++   V++             +  I + E  + + V +    T    
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV-- 685

Query: 422 GNLDSPSGSG---VLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASS 476
               S  GSG   V  +GS +   S   +     S   S  ++A    S + T  T  S 
Sbjct: 686 ----STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 477 SSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSV 536
           ++  S +  G ++ S+  T  E+   S +S    S  +   ++ S    + T    T  V
Sbjct: 742 TTTASTE--GSETTSASTTGSETTTASTTS----SETTMASIMGSETTMASTIGSETTKV 795

Query: 537 KTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 596
            T  S+       N+  +  +  T  S+  T   A       S  G + T   S   S +
Sbjct: 796 STASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 597 SVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLD 656
           +  S  G+    +   S  T T  ++ + T     + ++ +G     T +    ++ +  
Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGSET-----TTASTEGSETTTTSTEGSETTTAST 908

Query: 657 EKSR--TMSRSGS-----FRDGFE----EVHGSSLSLVSSTSS--VYSTPEEKCQSEIRK 703
           E S   T+S +GS       +G E       GS L+ VS+T S  +  + E    + +  
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968

Query: 704 LRRELDASQEKVSALTTQLTANAHLVAA 731
           +  E   +    S  TT  TA +    A
Sbjct: 969 MGSETTTASTAGSETTTVSTAGSETTTA 996



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 113/591 (19%), Positives = 219/591 (37%), Gaps = 42/591 (7%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++ +S         ST+   T+++ +  + T  ++    +  T + + S+    
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT 896

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S    +    S  GS+       GS+     ++ S+ +  ST G +   +S TGS    +
Sbjct: 897  STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            +A+   T   T  +       T  T  ++   VS  G  +  AS ++ S +    S+G E
Sbjct: 957  SAEGSET---TTVTTMGSETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVSSTGSE 1012

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAG---LAMITASGVTVT-----SRSATLGKIP 239
            +     S++ T T   ++ G +  + + AG    A+ T    T T     S + T+    
Sbjct: 1013 T--TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              +   S +    +++  + +         S T   Y +  + + +++        ST+S
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 300  IDSNISSKSAGLPVPKLREPSKT---------ALGSSLPGLVNQTDKEKGISSDNESVAS 350
             ++  +S +           S+T         A  SS  G    T   +G  +   S A 
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 351  CNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVV 410
              +   + A    ++ A TS           S T      G  T    I  +E+   S  
Sbjct: 1191 SETTTASTAGSETTT-ASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTA 1249

Query: 411  ISNPHATMTQQGNLD----SPSGSGVLSSGSSSPLY--SKNVDLNQSPLASSPSSAHSAP 464
               P AT            + SG+   S+  SS  +  +K  D++  P+ ++P S     
Sbjct: 1250 SLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309

Query: 465  SNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKD 524
               LT     +SSS     G+ F + ++ HT      I L++ G+ +         S+  
Sbjct: 1310 GTRLT-----ASSSVTMAPGMDFTASAASHT---VPGIVLNTSGLGTSTMGASSTTSAHG 1361

Query: 525  DSLTPFVRTNSVKTTLSESDP-HLDRNTLPKKGLRYTPTSQLRTQEDAKEW 574
               T         +T  E+ P  +  NT+    + +TPT+ ++     + W
Sbjct: 1362 VRTTTGSTREPTSSTFQETGPVSMGTNTV---SMSHTPTNVIKPSGYLQPW 1409



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 137/738 (18%), Positives = 260/738 (35%), Gaps = 89/738 (12%)

Query: 5    RNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQV 64
            R +TS + S + +   + +   +ST+   T++   + + T   S    +  T + + S++
Sbjct: 663  RTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWR 124
               S+   +    S  GS++      GS+     +  S+ +  ST+  +  + S  GS  
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS-E 781

Query: 125  RGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSS 184
              M + +G     TK S  +  + T  T  ++    S              S +    ++
Sbjct: 782  TTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS-----------TTASETTTVSTA 828

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
            G E+     + S T T  +   G +  + S  G    TAS  +  + +AT      ++A 
Sbjct: 829  GSETIPASTAGSETTTTTSTE-GSETTTASTEGSETTTASTESSETTTATTIGSETTTAS 887

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSN- 303
               S    +S +G++                  +    S+  + +  G+ ++T+S + + 
Sbjct: 888  TEGSETTTTSTEGSETT---------------TASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 304  -ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQP 362
              ++ + G  +  +       +  S  G    T    G  +   S A   +  V+ A   
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA--- 989

Query: 363  VSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQG 422
              S   T+   G++   V+S        G  T  V     E    S   S    T+T  G
Sbjct: 990  -GSETTTASIEGSETTTVSST-------GSETTTVSTTGTETTITSTEGSET-TTVTTAG 1040

Query: 423  NLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSK 482
            +      + V ++GS +   S           S  ++  +  S + T  T    ++ VS 
Sbjct: 1041 S----ETTAVYTTGSETTTTSTE--------GSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 483  DGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSE 542
             G G  + S+  +   ++ I+ S     S   S     S+     T    T S  TT+  
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV-- 1146

Query: 543  SDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPS 602
                            +T  S+  T         + SA G + T  ++  S  ++ ++  
Sbjct: 1147 ----------------FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 603  GTRFNFSQLASPTTVTQMSLSNP-TMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRT 661
                  S   S TT    S S   T   T S ++        T++ F   S S      T
Sbjct: 1191 SETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSES------T 1244

Query: 662  MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVS----- 716
            ++ + S       + GS  + VS T+S  +       S    L +  D S + ++     
Sbjct: 1245 IASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304

Query: 717  ---ALTTQLTANAHLVAA 731
                  T+LTA++ +  A
Sbjct: 1305 GTRTTGTRLTASSSVTMA 1322



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 123/739 (16%), Positives = 258/739 (34%), Gaps = 77/739 (10%)

Query: 173 VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRS 232
           +K S +    ++G E+  P P+ S+T   + +  G +  + S AG    T S        
Sbjct: 30  IKASETTTASTAGSETTTPSPTGSQTTIVSIS--GSEITTTSTAGSENTTVSS---AGSG 84

Query: 233 ATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAG 292
            T   +  S   VS +    +++     +     A+ S T     +    S++   + AG
Sbjct: 85  TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTT---SSETTVTSTAG 141

Query: 293 NRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCN 352
           + ++T S        + G               +S  G    T    G  +   S A   
Sbjct: 142 SETTTVS--------TVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412
           +  V+ A    ++ + T  +        +  T     G + TK   ++TA    +   +S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK---VSTA---GSETTVS 247

Query: 413 NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGT 472
              +  T     DS + +       ++   +   +       ++ S+  S P+ + T G+
Sbjct: 248 TAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE------TTAASTTGSEPTMASTMGS 301

Query: 473 NASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVR 532
             + +S +  +       + + T+   +    ++G      S+ G               
Sbjct: 302 ETTMASTIGPE------TTKVSTASSEVTTVFAAGSETIRASTVG-------------SE 342

Query: 533 TNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPF 592
           T +V TT SE+       T    G      S+  T         + S  G + T A++  
Sbjct: 343 TTTVSTTGSET------TTASIMG------SETSTDSTTGSETTTASTEGSETTTASTEG 390

Query: 593 SSGSSVTSPSGTRFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSNADGQYDPYTDSR 647
           S  ++V++        S   S TT T     +M+  + T+  T + S    +    + S 
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 648 FRNSSMSLD-EKSRTMSRSGS-----FRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEI 701
              ++ S +  ++ T++ +GS     +  G E    S+  L ++T     +      +E 
Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG 510

Query: 702 RKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDS---ELN 758
            +    + A+  +++ ++T+ + N  +     ++    T  L++ T + E  +       
Sbjct: 511 SE-TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569

Query: 759 ELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSAT 818
               T +  +     A +       T       N TA +AD       ++ S ++  S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629

Query: 819 SHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLP 878
           S  +  ++ E             ++     G   S ++ +S    E  T S+  S   + 
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTG---SERTITSTEGSETTTVSATGSETTVS 686

Query: 879 HNGSTGSTPLLRNSHSNSL 897
             GS  +T  +  S +  +
Sbjct: 687 TEGSGTTTVSITGSETTKV 705


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 152/824 (18%), Positives = 306/824 (37%), Gaps = 51/824 (6%)

Query: 14   SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
            ++ +S     +  +ST    T++  +  + T A+S    +  T +   S+    S    +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 74   DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
                S  GS++       S+     ++ S+ +  ST+  +  ++S TGS  R +T+  G 
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS-ERTITSTEGS 671

Query: 134  TMPRTKPSAPAGALKTPGTGKTDDAKV-SEKGRLSPKASQVKRSPSDAGR---SSGDESK 189
                   +     + T G+G T  +   SE  ++S   S+   + ++      +S   S+
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 190  KPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSA 249
                S+  + T  A++ G +  S S  G    TAS    TS   T+  I  S   ++ + 
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTAS---TTSSETTMASIMGSETTMASTI 788

Query: 250  GRKSS-MDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            G +++ +  A ++       +S T +   +    +  ++       +ST+  ++  ++ +
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTST 848

Query: 309  AGLPVPKLR-EPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
             G        E S+T   S+     ++T     I S+  + ++  S     + +   S  
Sbjct: 849  EGSETTTASTEGSETTTASTES---SETTTATTIGSETTTASTEGSETTTTSTE--GSET 903

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T+   G++   V++             +   A+ E  + + V +    T+T        
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSET 963

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            +    + S +++   + +     S   S  ++A    S + T  +  S ++ VS  G   
Sbjct: 964  TTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTET 1023

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
               S+  +   ++  + S         S     S++    T    T S  TT S +D  L
Sbjct: 1024 TITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTAD--L 1081

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFN 607
            +  T+   G   T T+     E    ++      G + T A++  S  ++V++ S     
Sbjct: 1082 ETTTVSTSGSG-TTTASTAGSETTTVYIT-----GSKTTTASTEGSEATTVSTTSSETTT 1135

Query: 608  FSQLASPTTVTQMSLSNPTMLRT----HSLSNADGQY--DPYTDSRFRNSSMSLDEKSRT 661
             S   S  T    ++S  T + T     + S+A G       T+     ++ +   ++ T
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTT 1195

Query: 662  MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQ 721
             S +GS         GS  +   +T S  STP                A  E  +A    
Sbjct: 1196 ASTAGS-ETTTASTSGSETNTACTTGSETSTPSS--------------AGSETNTAFIIG 1240

Query: 722  LTANAHLVAAFEQSLGNMT-IRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAING 780
                    A+ E +  ++T     ++++TA    +    +  T  +L K   A   +I  
Sbjct: 1241 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK---ATDVSIQP 1297

Query: 781  VINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVG 824
            + NTP    +  GT  +A   +      D  +   SA SH+  G
Sbjct: 1298 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTA---SAASHTVPG 1338



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 137/699 (19%), Positives = 257/699 (36%), Gaps = 46/699 (6%)

Query: 14  SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
           ++V+          ST    T++ +   + T  +S    +  T +   SQ    S+   +
Sbjct: 5   TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE 64

Query: 74  DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
               S  GS++      GS      S    E+  ST+G +   +S TG+    ++A    
Sbjct: 65  ITTTSTAGSENTTVSSAGSG-TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 134 TMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGR------SSGDE 187
           T   +  S+      T G+  T  + V  +   +  A     + S  G       ++G E
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE 183

Query: 188 SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV-TVTSRSATLGKIPKSSALVS 246
           +  P  + S T T   ++ G +  + S  G    TAS   + T+ ++T+G    S     
Sbjct: 184 TITPSTAGSETTT--VSTAGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKV 237

Query: 247 RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
            +AG ++++  A ++        S TN  +    + + +++       +ST+  +  ++S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 307 KSAGLPVPKLR---EPSKTALGSSLPGLV----NQTDKEKGISSDNESVASCNSVKVNPA 359
                         E +K +  SS    V    ++T +   + S+  +V++  S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS--ETTT 355

Query: 360 AQPVSSPAQTSLQPGAKYPDVA---SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHA 416
           A  + S   T    G++    +   S T      G     V    +E    S+  S    
Sbjct: 356 ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTT 415

Query: 417 TMTQQGNLDSPSGS---GVLSSGSSSPLYSKNVDLNQSPLASSPSS----AHSAPSNSLT 469
           T T+   + + S +      +S   S +   +   +++  AS+  S      +A S + T
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475

Query: 470 WGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP 529
             T  S ++  S  GL   +V ++ +   +     S     S   S     S++    T 
Sbjct: 476 AYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTT 535

Query: 530 FVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
              T S  TT+S +   L+  T   +G      S++ T         + S  G   TAA+
Sbjct: 536 VSTTGSETTTVSTTG--LETTTTSTEG------SEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 590 SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFR 649
           +  S  ++V++        S   S TT    + S  T   T S           T+    
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS----TEGSET 643

Query: 650 NSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSS 688
            +  + D ++  +S +GS R       GS  + VS+T S
Sbjct: 644 TTVSTTDSETTMVSTTGSERT-ITSTEGSETTTVSATGS 681



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 116/635 (18%), Positives = 229/635 (36%), Gaps = 60/635 (9%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++VS+  S+TI           +S +    T  +S +  +  T + + S+    
Sbjct: 817  TTASETTTVSTAGSETI----------PASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S  S +    +  GS++      GS+     ++ S+ +  ST G +   +S TGS     
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            + +   T   T  S     L T  T  ++   VS +G  +   + +  S +    ++G E
Sbjct: 927  STEGSET---TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM-GSETTTASTAGSE 982

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247
            +     + S T TA+          GS       T S  T  S + T       + + S 
Sbjct: 983  TTTVSTAGSETTTASI--------EGSETTTVSSTGSETTTVSTTGT------ETTITST 1028

Query: 248  SAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSK 307
                 +++  A ++        S T            + S  G+   + +++     ++ 
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETT-----------TTSTEGSETTTVSTTGSETTTAS 1077

Query: 308  SAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
            +A L    +         +S  G    T    G  +   S     +  V+  +   ++ +
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAS 1137

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T  +    +  V+  T     G + T     A +E    S   S      T      + 
Sbjct: 1138 TTGSEMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTEGSETTTASTAGSETTTA 1196

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            S +G  ++ +S+     N         S+PSSA S  + +   G+  + +S  S +    
Sbjct: 1197 STAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTA- 1255

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
             S++   T+  SI  S ++    + +S+T ++  + D S+ P   T    T  + +    
Sbjct: 1256 TSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA 1315

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGG--LQDTAANSPFSSGSSVTSPSGTR 605
              +     G+ +T ++             SH+  G  L  +   +     SS TS  G R
Sbjct: 1316 SSSVTMAPGMDFTASA------------ASHTVPGIVLNTSGLGTSTMGASSTTSAHGVR 1363

Query: 606  FNFSQLASPTTVT-----QMSLSNPTMLRTHSLSN 635
                    PT+ T      +S+   T+  +H+ +N
Sbjct: 1364 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTN 1398



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 150/814 (18%), Positives = 301/814 (36%), Gaps = 77/814 (9%)

Query: 6   NLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVE 65
           N T+  +++  S+  S+T   +ST    T+++ ++ + T A+S    ++ T     S+  
Sbjct: 127 NSTTSSETTVTSTAGSETT-TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185

Query: 66  RNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR 125
             S    +    S  GS++      GS+     +  S+ +  ST G +   +S  GS   
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 126 GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
             TA    T   T+ S          T  T+D+K +       + +    + S+   +S 
Sbjct: 246 VSTAGSETTAASTEDS-------ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 186 DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALV 245
             S+  + S+    T   ++   +  +  AAG   I AS  TV S + T+      +   
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS--TVGSETTTVSTTGSETTTA 356

Query: 246 SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI-DSNI 304
           S   G ++S D     +      S+  +    +    S++ + +  G+ ++T SI DS  
Sbjct: 357 S-IMGSETSTDSTTGSET--TTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 305 S------SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKE------KGISSDNESVASCN 352
           +      S+   +        + +  GS +  + + +D E      +G  +   + A   
Sbjct: 414 TTTCTEGSEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT------KQVPIATAENMK 406
           +          ++ + T L+    +   +  T     G + T       ++   + E  +
Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 407 NSVVISNPHATMT-------------------------QQGNLDSPSGSGVL---SSGSS 438
           N+ V +    T T                          +   DS  GSG     ++GS 
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 439 SPLYS--KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTS 496
           +   S   + +   S   S  +SA +  S + T  T +S ++  S +G    +VS+  + 
Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 497 CESIDISLSSGGVPS-HNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKK 555
              +  + S   + S   S T  ++++  ++      + +   +++ S+      T  + 
Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSET 712

Query: 556 GLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPT 615
               T  S++ T         + S  G + T A++  S  +S ++        S  +S T
Sbjct: 713 TTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772

Query: 616 TVTQMSLSNPTML-----RTHSLSNADGQYDP-YTDSRFRNSSMSLDEKSRTMSRSGSFR 669
           T+  +  S  TM       T  +S A  +    +T++     + +   ++ T+S +GS  
Sbjct: 773 TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-- 830

Query: 670 DGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLV 729
              E +  S+    S T++  ST   +  +   +      AS E     T     +    
Sbjct: 831 ---ETIPASTAG--SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 730 AAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKT 763
           A+ E S    T    S T TA  + SE+  +  T
Sbjct: 886 ASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 919



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 136/748 (18%), Positives = 273/748 (36%), Gaps = 64/748 (8%)

Query: 4   PRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQ 63
           P   ++    ++++S I      +ST     ++  ++ + T  +S    +  T +   S+
Sbjct: 293 PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSE 352

Query: 64  VERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
               S+   +    S  GS++      GS+     ++ S+ +  ST+G +   +S T S 
Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS- 411

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRS 183
               T   G  M     +A +  +    T  T+ ++++         +    S +    +
Sbjct: 412 ETTTTCTEGSEM-----TAVSTTVFETTTASTEGSEIT--------IASTSDSETTTAST 458

Query: 184 SGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSA 243
            G E+     + S T TA         ++ +A+   + T +  T+ S + T       + 
Sbjct: 459 EGSETTTVTTAGSETKTAYTTG----SETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 244 LVSRSAGRKS--SMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
            VS +    +  S +G++N        S  T +    L   + S   +     S+T +  
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTG-SETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 302 SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
           +  S++ +G           T + ++       ++     ++D+E+ ++  +      A 
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTA------DSENTTASTADSETTSASTTGSETTTAS 627

Query: 362 PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQ 421
             SS   T+   G++   V++             +  I + E  + + V +    T    
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV-- 685

Query: 422 GNLDSPSGSG---VLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASS 476
               S  GSG   V  +GS +   S   +     S   S  ++A    S + T  T  S 
Sbjct: 686 ----STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 477 SSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSV 536
           ++  S +  G ++ S+  T  E+   S +S    S  +   ++ S    + T    T  V
Sbjct: 742 TTTASTE--GSETTSASTTGSETTTASTTS----SETTMASIMGSETTMASTIGSETTKV 795

Query: 537 KTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 596
            T  S+       N+  +  +  T  S+  T   A       S  G + T   S   S +
Sbjct: 796 STASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 597 SVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLD 656
           +  S  G+    +   S  T T  ++ + T     + ++ +G     T +    ++ +  
Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGSET-----TTASTEGSETTTTSTEGSETTTAST 908

Query: 657 EKSR--TMSRSGS-----FRDGFE----EVHGSSLSLVSSTSS--VYSTPEEKCQSEIRK 703
           E S   T+S +GS       +G E       GS L+ VS+T S  +  + E    + +  
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968

Query: 704 LRRELDASQEKVSALTTQLTANAHLVAA 731
           +  E   +    S  TT  TA +    A
Sbjct: 969 MGSETTTASTAGSETTTVSTAGSETTTA 996



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 113/591 (19%), Positives = 218/591 (36%), Gaps = 42/591 (7%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++ +S         ST+   T+++ +  + T  ++    +  T + + S+    
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT 896

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S    +    S  GS+       GS+     ++ S+ +  ST G +   +S TGS    +
Sbjct: 897  STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            +A+   T   T  +       T  T  ++   VS  G  +  AS ++ S +    S+G E
Sbjct: 957  SAEGSET---TTVTTMGSETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVSSTGSE 1012

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAG---LAMITASGVTVT-----SRSATLGKIP 239
            +     S++ T T   ++ G +  + + AG    A+ T    T T     S + T+    
Sbjct: 1013 T--TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              +   S +    +++  + +         S T   Y +  + + +++        ST+S
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 300  IDSNISSKSAGLPVPKLREPSKT---------ALGSSLPGLVNQTDKEKGISSDNESVAS 350
             ++  +S +           S+T         A  SS  G    T   +G  +   S A 
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 351  CNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVV 410
              +   + A    ++ A TS           S T      G  T    I  +E    S  
Sbjct: 1191 SETTTASTAGSETTT-ASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTA 1249

Query: 411  ISNPHATMTQQGNLD----SPSGSGVLSSGSSSPLY--SKNVDLNQSPLASSPSSAHSAP 464
               P AT            + SG+   S+  SS  +  +K  D++  P+ ++P S     
Sbjct: 1250 SLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309

Query: 465  SNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKD 524
               LT     +SSS     G+ F + ++ HT      I L++ G+ +         S+  
Sbjct: 1310 GTRLT-----ASSSVTMAPGMDFTASAASHT---VPGIVLNTSGLGTSTMGASSTTSAHG 1361

Query: 525  DSLTPFVRTNSVKTTLSESDP-HLDRNTLPKKGLRYTPTSQLRTQEDAKEW 574
               T         +T  E+ P  +  NT+    + +TPT+ ++     + W
Sbjct: 1362 VRTTTGSTREPTSSTFQETGPVSMGTNTV---SMSHTPTNVIKPSGYLQPW 1409



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 123/638 (19%), Positives = 232/638 (36%), Gaps = 62/638 (9%)

Query: 5    RNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQV 64
            R +TS + S + +   + +   +ST+   T++   + + T   S    +  T + + S++
Sbjct: 663  RTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWR 124
               S+   +    S  GS++      GS+     +  S+ +  ST+  +  + S  GS  
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS-E 781

Query: 125  RGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSS 184
              M + +G     TK S  +  + T  T  ++    S              S +    ++
Sbjct: 782  TTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS-----------TTASETTTVSTA 828

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
            G E+     + S T T  +   G +  + S  G    TAS  +  + +AT      ++A 
Sbjct: 829  GSETIPASTAGSETTTTTSTE-GSETTTASTEGSETTTASTESSETTTATTIGSETTTAS 887

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSN- 303
               S    +S +G++                  +    S+  + +  G+ ++T+S + + 
Sbjct: 888  TEGSETTTTSTEGSETT---------------TASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 304  -ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQP 362
              ++ + G  +  +       +  S  G    T    G  +   S A   +  V+ A   
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA--- 989

Query: 363  VSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQG 422
              S   T+   G++   V+S        G  T  V     E    S   S    T+T  G
Sbjct: 990  -GSETTTASIEGSETTTVSST-------GSETTTVSTTGTETTITSTEGSET-TTVTTAG 1040

Query: 423  NLDSPSGSGVLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAV 480
            +      + V ++GS +   S   +     S   S  ++A +A   + T  T+ S ++  
Sbjct: 1041 S----ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTA 1096

Query: 481  SKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTL 540
            S  G    +V    +   +     S     S  SS    AS+    +T    T S  TT+
Sbjct: 1097 STAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTV 1156

Query: 541  SESDPHLDRNTLPKKGLRYTPT--SQLRTQEDAKEWLRSHSAGGLQDTAA-------NSP 591
            S        ++        T T  S+  T   A     + S  G + T A       N+ 
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216

Query: 592  FSSGSSVTSPS--GTRFNFS-QLASPTTVTQMSLSNPT 626
             ++GS  ++PS  G+  N +  + S TT+   +   PT
Sbjct: 1217 CTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPT 1254



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 123/739 (16%), Positives = 258/739 (34%), Gaps = 77/739 (10%)

Query: 173 VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRS 232
           +K S +    ++G E+  P P+ S+T   + +  G +  + S AG    T S        
Sbjct: 30  IKASETTTASTAGSETTTPSPTGSQTTIVSIS--GSEITTTSTAGSENTTVSS---AGSG 84

Query: 233 ATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAG 292
            T   +  S   VS +    +++     +     A+ S T     +    S++   + AG
Sbjct: 85  TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTT---SSETTVTSTAG 141

Query: 293 NRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCN 352
           + ++T S        + G               +S  G    T    G  +   S A   
Sbjct: 142 SETTTVS--------TVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412
           +  V+ A    ++ + T  +        +  T     G + TK   ++TA    +   +S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK---VSTA---GSETTVS 247

Query: 413 NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGT 472
              +  T     DS + +       ++   +   +       ++ S+  S P+ + T G+
Sbjct: 248 TAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE------TTAASTTGSEPTMASTMGS 301

Query: 473 NASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVR 532
             + +S +  +       + + T+   +    ++G      S+ G               
Sbjct: 302 ETTMASTIGPE------TTKVSTASSEVTTVFAAGSETIRASTVG-------------SE 342

Query: 533 TNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPF 592
           T +V TT SE+       T    G      S+  T         + S  G + T A++  
Sbjct: 343 TTTVSTTGSET------TTASIMG------SETSTDSTTGSETTTASTEGSETTTASTEG 390

Query: 593 SSGSSVTSPSGTRFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSNADGQYDPYTDSR 647
           S  ++V++        S   S TT T     +M+  + T+  T + S    +    + S 
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 648 FRNSSMSLD-EKSRTMSRSGS-----FRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEI 701
              ++ S +  ++ T++ +GS     +  G E    S+  L ++T     +      +E 
Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG 510

Query: 702 RKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDS---ELN 758
            +    + A+  +++ ++T+ + N  +     ++    T  L++ T + E  +       
Sbjct: 511 SE-TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569

Query: 759 ELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSAT 818
               T +  +     A +       T       N TA +AD       ++ S ++  S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629

Query: 819 SHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLP 878
           S  +  ++ E             ++     G   S ++ +S    E  T S+  S   + 
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTG---SERTITSTEGSETTTVSATGSETTVS 686

Query: 879 HNGSTGSTPLLRNSHSNSL 897
             GS  +T  +  S +  +
Sbjct: 687 TEGSGTTTVSITGSETTKV 705


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 152/824 (18%), Positives = 306/824 (37%), Gaps = 51/824 (6%)

Query: 14   SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
            ++ +S     +  +ST    T++  +  + T A+S    +  T +   S+    S    +
Sbjct: 574  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 633

Query: 74   DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
                S  GS++       S+     ++ S+ +  ST+  +  ++S TGS  R +T+  G 
Sbjct: 634  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS-ERTITSTEGS 692

Query: 134  TMPRTKPSAPAGALKTPGTGKTDDAKV-SEKGRLSPKASQVKRSPSDAGR---SSGDESK 189
                   +     + T G+G T  +   SE  ++S   S+   + ++      +S   S+
Sbjct: 693  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 752

Query: 190  KPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSA 249
                S+  + T  A++ G +  S S  G    TAS    TS   T+  I  S   ++ + 
Sbjct: 753  TTTASTEGSETTTASTEGSETTSASTTGSETTTAS---TTSSETTMASIMGSETTMASTI 809

Query: 250  GRKSS-MDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            G +++ +  A ++       +S T +   +    +  ++       +ST+  ++  ++ +
Sbjct: 810  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTST 869

Query: 309  AGLPVPKLR-EPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
             G        E S+T   S+     ++T     I S+  + ++  S     + +   S  
Sbjct: 870  EGSETTTASTEGSETTTASTES---SETTTATTIGSETTTASTEGSETTTTSTE--GSET 924

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T+   G++   V++             +   A+ E  + + V +    T+T        
Sbjct: 925  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSET 984

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            +    + S +++   + +     S   S  ++A    S + T  +  S ++ VS  G   
Sbjct: 985  TTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTET 1044

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
               S+  +   ++  + S         S     S++    T    T S  TT S +D  L
Sbjct: 1045 TITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTAD--L 1102

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFN 607
            +  T+   G   T T+     E    ++      G + T A++  S  ++V++ S     
Sbjct: 1103 ETTTVSTSGSG-TTTASTAGSETTTVYIT-----GSKTTTASTEGSEATTVSTTSSETTT 1156

Query: 608  FSQLASPTTVTQMSLSNPTMLRT----HSLSNADGQY--DPYTDSRFRNSSMSLDEKSRT 661
             S   S  T    ++S  T + T     + S+A G       T+     ++ +   ++ T
Sbjct: 1157 ASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTT 1216

Query: 662  MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQ 721
             S +GS         GS  +   +T S  STP                A  E  +A    
Sbjct: 1217 ASTAGS-ETTTASTSGSETNTACTTGSETSTPSS--------------AGSETNTAFIIG 1261

Query: 722  LTANAHLVAAFEQSLGNMT-IRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAING 780
                    A+ E +  ++T     ++++TA    +    +  T  +L K   A   +I  
Sbjct: 1262 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK---ATDVSIQP 1318

Query: 781  VINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVG 824
            + NTP    +  GT  +A   +      D  +   SA SH+  G
Sbjct: 1319 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTA---SAASHTVPG 1359



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 116/635 (18%), Positives = 229/635 (36%), Gaps = 60/635 (9%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++VS+  S+TI           +S +    T  +S +  +  T + + S+    
Sbjct: 838  TTASETTTVSTAGSETI----------PASTAGSETTTTTSTEGSETTTASTEGSETTTA 887

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S  S +    +  GS++      GS+     ++ S+ +  ST G +   +S TGS     
Sbjct: 888  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 947

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            + +   T   T  S     L T  T  ++   VS +G  +   + +  S +    ++G E
Sbjct: 948  STEGSET---TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM-GSETTTASTAGSE 1003

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247
            +     + S T TA+          GS       T S  T  S + T       + + S 
Sbjct: 1004 TTTVSTAGSETTTASI--------EGSETTTVSSTGSETTTVSTTGT------ETTITST 1049

Query: 248  SAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSK 307
                 +++  A ++        S T            + S  G+   + +++     ++ 
Sbjct: 1050 EGSETTTVTTAGSETTAVYTTGSETT-----------TTSTEGSETTTVSTTGSETTTAS 1098

Query: 308  SAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
            +A L    +         +S  G    T    G  +   S     +  V+  +   ++ +
Sbjct: 1099 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAS 1158

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T  +    +  V+  T     G + T     A +E    S   S      T      + 
Sbjct: 1159 TTGSEMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTEGSETTTASTAGSETTTA 1217

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            S +G  ++ +S+     N         S+PSSA S  + +   G+  + +S  S +    
Sbjct: 1218 STAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTA- 1276

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
             S++   T+  SI  S ++    + +S+T ++  + D S+ P   T    T  + +    
Sbjct: 1277 TSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA 1336

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGG--LQDTAANSPFSSGSSVTSPSGTR 605
              +     G+ +T ++             SH+  G  L  +   +     SS TS  G R
Sbjct: 1337 SSSVTMAPGMDFTASA------------ASHTVPGIVLNTSGLGTSTMGASSTTSAHGVR 1384

Query: 606  FNFSQLASPTTVT-----QMSLSNPTMLRTHSLSN 635
                    PT+ T      +S+   T+  +H+ +N
Sbjct: 1385 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTN 1419



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 150/814 (18%), Positives = 301/814 (36%), Gaps = 77/814 (9%)

Query: 6   NLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVE 65
           N T+  +++  S+  S+T   +ST    T+++ ++ + T A+S    ++ T     S+  
Sbjct: 148 NSTTSSETTVTSTAGSETT-TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 206

Query: 66  RNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR 125
             S    +    S  GS++      GS+     +  S+ +  ST G +   +S  GS   
Sbjct: 207 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 266

Query: 126 GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
             TA    T   T+ S          T  T+D+K +       + +    + S+   +S 
Sbjct: 267 VSTAGSETTAASTEDS-------ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 319

Query: 186 DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALV 245
             S+  + S+    T   ++   +  +  AAG   I AS  TV S + T+      +   
Sbjct: 320 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS--TVGSETTTVSTTGSETTTA 377

Query: 246 SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI-DSNI 304
           S   G ++S D     +      S+  +    +    S++ + +  G+ ++T SI DS  
Sbjct: 378 S-IMGSETSTDSTTGSET--TTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 434

Query: 305 S------SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKE------KGISSDNESVASCN 352
           +      S+   +        + +  GS +  + + +D E      +G  +   + A   
Sbjct: 435 TTTCTEGSEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGSE 493

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT------KQVPIATAENMK 406
           +          ++ + T L+    +   +  T     G + T       ++   + E  +
Sbjct: 494 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 553

Query: 407 NSVVISNPHATMT-------------------------QQGNLDSPSGSGVL---SSGSS 438
           N+ V +    T T                          +   DS  GSG     ++GS 
Sbjct: 554 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 613

Query: 439 SPLYS--KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTS 496
           +   S   + +   S   S  +SA +  S + T  T +S ++  S +G    +VS+  + 
Sbjct: 614 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 673

Query: 497 CESIDISLSSGGVPS-HNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKK 555
              +  + S   + S   S T  ++++  ++      + +   +++ S+      T  + 
Sbjct: 674 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSET 733

Query: 556 GLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPT 615
               T  S++ T         + S  G + T A++  S  +S ++        S  +S T
Sbjct: 734 TTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET 793

Query: 616 TVTQMSLSNPTML-----RTHSLSNADGQYDP-YTDSRFRNSSMSLDEKSRTMSRSGSFR 669
           T+  +  S  TM       T  +S A  +    +T++     + +   ++ T+S +GS  
Sbjct: 794 TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-- 851

Query: 670 DGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLV 729
              E +  S+    S T++  ST   +  +   +      AS E     T     +    
Sbjct: 852 ---ETIPASTAG--SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 906

Query: 730 AAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKT 763
           A+ E S    T    S T TA  + SE+  +  T
Sbjct: 907 ASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 940



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 136/748 (18%), Positives = 273/748 (36%), Gaps = 64/748 (8%)

Query: 4    PRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQ 63
            P   ++    ++++S I      +ST     ++  ++ + T  +S    +  T +   S+
Sbjct: 314  PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSE 373

Query: 64   VERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
                S+   +    S  GS++      GS+     ++ S+ +  ST+G +   +S T S 
Sbjct: 374  TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS- 432

Query: 124  RRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRS 183
                T   G  M     +A +  +    T  T+ ++++         +    S +    +
Sbjct: 433  ETTTTCTEGSEM-----TAVSTTVFETTTASTEGSEIT--------IASTSDSETTTAST 479

Query: 184  SGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSA 243
             G E+     + S T TA         ++ +A+   + T +  T+ S + T       + 
Sbjct: 480  EGSETTTVTTAGSETKTAYTTG----SETTTASNTGLETTTVFTIGSDTTTASTEGSETT 535

Query: 244  LVSRSAGRKS--SMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
             VS +    +  S +G++N        S  T +    L   + S   +     S+T +  
Sbjct: 536  AVSATGSEMTTVSTEGSENTTVSTTG-SETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 594

Query: 302  SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
            +  S++ +G           T + ++       ++     ++D+E+ ++  +      A 
Sbjct: 595  TTDSTEGSGTTAASTAGSETTTVSTA------DSENTTASTADSETTSASTTGSETTTAS 648

Query: 362  PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQ 421
              SS   T+   G++   V++             +  I + E  + + V +    T    
Sbjct: 649  TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV-- 706

Query: 422  GNLDSPSGSG---VLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASS 476
                S  GSG   V  +GS +   S   +     S   S  ++A    S + T  T  S 
Sbjct: 707  ----STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 762

Query: 477  SSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSV 536
            ++  S +  G ++ S+  T  E+   S +S    S  +   ++ S    + T    T  V
Sbjct: 763  TTTASTE--GSETTSASTTGSETTTASTTS----SETTMASIMGSETTMASTIGSETTKV 816

Query: 537  KTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 596
             T  S+       N+  +  +  T  S+  T   A       S  G + T   S   S +
Sbjct: 817  STASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 874

Query: 597  SVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLD 656
            +  S  G+    +   S  T T  ++ + T     + ++ +G     T +    ++ +  
Sbjct: 875  TTASTEGSETTTASTESSETTTATTIGSET-----TTASTEGSETTTTSTEGSETTTAST 929

Query: 657  EKSR--TMSRSGS-----FRDGFE----EVHGSSLSLVSSTSS--VYSTPEEKCQSEIRK 703
            E S   T+S +GS       +G E       GS L+ VS+T S  +  + E    + +  
Sbjct: 930  EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 989

Query: 704  LRRELDASQEKVSALTTQLTANAHLVAA 731
            +  E   +    S  TT  TA +    A
Sbjct: 990  MGSETTTASTAGSETTTVSTAGSETTTA 1017



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 113/591 (19%), Positives = 218/591 (36%), Gaps = 42/591 (7%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++ +S         ST+   T+++ +  + T  ++    +  T + + S+    
Sbjct: 858  TAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT 917

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S    +    S  GS+       GS+     ++ S+ +  ST G +   +S TGS    +
Sbjct: 918  STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 977

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            +A+   T   T  +       T  T  ++   VS  G  +  AS ++ S +    S+G E
Sbjct: 978  SAEGSET---TTVTTMGSETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVSSTGSE 1033

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAG---LAMITASGVTVT-----SRSATLGKIP 239
            +     S++ T T   ++ G +  + + AG    A+ T    T T     S + T+    
Sbjct: 1034 T--TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1091

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              +   S +    +++  + +         S T   Y +  + + +++        ST+S
Sbjct: 1092 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1151

Query: 300  IDSNISSKSAGLPVPKLREPSKT---------ALGSSLPGLVNQTDKEKGISSDNESVAS 350
             ++  +S +           S+T         A  SS  G    T   +G  +   S A 
Sbjct: 1152 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1211

Query: 351  CNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVV 410
              +   + A    ++ A TS           S T      G  T    I  +E    S  
Sbjct: 1212 SETTTASTAGSETTT-ASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTA 1270

Query: 411  ISNPHATMTQQGNLD----SPSGSGVLSSGSSSPLY--SKNVDLNQSPLASSPSSAHSAP 464
               P AT            + SG+   S+  SS  +  +K  D++  P+ ++P S     
Sbjct: 1271 SLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1330

Query: 465  SNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKD 524
               LT     +SSS     G+ F + ++ HT      I L++ G+ +         S+  
Sbjct: 1331 GTRLT-----ASSSVTMAPGMDFTASAASHT---VPGIVLNTSGLGTSTMGASSTTSAHG 1382

Query: 525  DSLTPFVRTNSVKTTLSESDP-HLDRNTLPKKGLRYTPTSQLRTQEDAKEW 574
               T         +T  E+ P  +  NT+    + +TPT+ ++     + W
Sbjct: 1383 VRTTTGSTREPTSSTFQETGPVSMGTNTV---SMSHTPTNVIKPSGYLQPW 1430



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 141/722 (19%), Positives = 264/722 (36%), Gaps = 72/722 (9%)

Query: 18  SGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGDDVKK 77
           +G   T  + +   + T+SS+SS      ++  N    T +   S+     + + +    
Sbjct: 2   AGSEATTTSTADSKVITASSMSSETTVAPAAGSN--TTTASTTGSETTTILIKASETTTA 59

Query: 78  SDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR------------ 125
           S  GS++      GS+        S+ +  ST+G +N  +S  GS               
Sbjct: 60  STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTIS 119

Query: 126 ---GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKV-----SEKGRLSPKASQVKR-- 175
                T  V IT   T   +  G+  T  +  + +  V     SE   +S   S+     
Sbjct: 120 TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 179

Query: 176 ---SPSDAGRSSGDE--------SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITAS 224
              S + A  ++G E        S+   PS++ + T   ++ G +  + S  G    TAS
Sbjct: 180 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAS 239

Query: 225 GV-TVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPS 283
              + T+ ++T+G    S      +AG ++++  A ++        S TN  +    + +
Sbjct: 240 TAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTT 295

Query: 284 KSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLR---EPSKTALGSSLPGLV----NQTD 336
            +++       +ST+  +  ++S              E +K +  SS    V    ++T 
Sbjct: 296 TASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 355

Query: 337 KEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVA---SPTLRRLFGGKP 393
           +   + S+  +V++  S      A  + S   T    G++    +   S T      G  
Sbjct: 356 RASTVGSETTTVSTTGS--ETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 413

Query: 394 TKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGS---GVLSSGSSSPLYSKNVDLNQ 450
              V    +E    S+  S    T T+   + + S +      +S   S +   +   ++
Sbjct: 414 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 473

Query: 451 SPLASSPSS----AHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSS 506
           +  AS+  S      +A S + T  T  S ++  S  GL   +V ++ +   +     S 
Sbjct: 474 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSE 533

Query: 507 GGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLR 566
               S   S     S++    T    T S  TT+S +   L+  T   +G      S++ 
Sbjct: 534 TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG--LETTTTSTEG------SEMT 585

Query: 567 TQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPT 626
           T         + S  G   TAA++  S  ++V++        S   S TT    + S  T
Sbjct: 586 TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 645

Query: 627 MLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSST 686
              T S           T+     +  + D ++  +S +GS R       GS  + VS+T
Sbjct: 646 TASTTSSETTTAS----TEGSETTTVSTTDSETTMVSTTGSERT-ITSTEGSETTTVSAT 700

Query: 687 SS 688
            S
Sbjct: 701 GS 702



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 123/638 (19%), Positives = 232/638 (36%), Gaps = 62/638 (9%)

Query: 5    RNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQV 64
            R +TS + S + +   + +   +ST+   T++   + + T   S    +  T + + S++
Sbjct: 684  RTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 743

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWR 124
               S+   +    S  GS++      GS+     +  S+ +  ST+  +  + S  GS  
Sbjct: 744  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS-E 802

Query: 125  RGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSS 184
              M + +G     TK S  +  + T  T  ++    S              S +    ++
Sbjct: 803  TTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS-----------TTASETTTVSTA 849

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
            G E+     + S T T  +   G +  + S  G    TAS  +  + +AT      ++A 
Sbjct: 850  GSETIPASTAGSETTTTTSTE-GSETTTASTEGSETTTASTESSETTTATTIGSETTTAS 908

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSN- 303
               S    +S +G++                  +    S+  + +  G+ ++T+S + + 
Sbjct: 909  TEGSETTTTSTEGSETT---------------TASTEGSEITTVSTTGSETTTASTEGSE 953

Query: 304  -ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQP 362
              ++ + G  +  +       +  S  G    T    G  +   S A   +  V+ A   
Sbjct: 954  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA--- 1010

Query: 363  VSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQG 422
              S   T+   G++   V+S        G  T  V     E    S   S    T+T  G
Sbjct: 1011 -GSETTTASIEGSETTTVSST-------GSETTTVSTTGTETTITSTEGSET-TTVTTAG 1061

Query: 423  NLDSPSGSGVLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAV 480
            +      + V ++GS +   S   +     S   S  ++A +A   + T  T+ S ++  
Sbjct: 1062 S----ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTA 1117

Query: 481  SKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTL 540
            S  G    +V    +   +     S     S  SS    AS+    +T    T S  TT+
Sbjct: 1118 STAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTV 1177

Query: 541  SESDPHLDRNTLPKKGLRYTPT--SQLRTQEDAKEWLRSHSAGGLQDTAA-------NSP 591
            S        ++        T T  S+  T   A     + S  G + T A       N+ 
Sbjct: 1178 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1237

Query: 592  FSSGSSVTSPS--GTRFNFS-QLASPTTVTQMSLSNPT 626
             ++GS  ++PS  G+  N +  + S TT+   +   PT
Sbjct: 1238 CTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPT 1275


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 152/824 (18%), Positives = 306/824 (37%), Gaps = 51/824 (6%)

Query: 14   SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
            ++ +S     +  +ST    T++  +  + T A+S    +  T +   S+    S    +
Sbjct: 553  TTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 74   DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
                S  GS++       S+     ++ S+ +  ST+  +  ++S TGS  R +T+  G 
Sbjct: 613  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGS-ERTITSTEGS 671

Query: 134  TMPRTKPSAPAGALKTPGTGKTDDAKV-SEKGRLSPKASQVKRSPSDAGR---SSGDESK 189
                   +     + T G+G T  +   SE  ++S   S+   + ++      +S   S+
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSE 731

Query: 190  KPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSA 249
                S+  + T  A++ G +  S S  G    TAS    TS   T+  I  S   ++ + 
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTAS---TTSSETTMASIMGSETTMASTI 788

Query: 250  GRKSS-MDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS 308
            G +++ +  A ++       +S T +   +    +  ++       +ST+  ++  ++ +
Sbjct: 789  GSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTST 848

Query: 309  AGLPVPKLR-EPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
             G        E S+T   S+     ++T     I S+  + ++  S     + +   S  
Sbjct: 849  EGSETTTASTEGSETTTASTES---SETTTATTIGSETTTASTEGSETTTTSTE--GSET 903

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T+   G++   V++             +   A+ E  + + V +    T+T        
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSET 963

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            +    + S +++   + +     S   S  ++A    S + T  +  S ++ VS  G   
Sbjct: 964  TTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTET 1023

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
               S+  +   ++  + S         S     S++    T    T S  TT S +D  L
Sbjct: 1024 TITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTAD--L 1081

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFN 607
            +  T+   G   T T+     E    ++      G + T A++  S  ++V++ S     
Sbjct: 1082 ETTTVSTSGSG-TTTASTAGSETTTVYIT-----GSKTTTASTEGSEATTVSTTSSETTT 1135

Query: 608  FSQLASPTTVTQMSLSNPTMLRT----HSLSNADGQY--DPYTDSRFRNSSMSLDEKSRT 661
             S   S  T    ++S  T + T     + S+A G       T+     ++ +   ++ T
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTT 1195

Query: 662  MSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQ 721
             S +GS         GS  +   +T S  STP                A  E  +A    
Sbjct: 1196 ASTAGS-ETTTASTSGSETNTACTTGSETSTPSS--------------AGSETNTAFIIG 1240

Query: 722  LTANAHLVAAFEQSLGNMT-IRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAING 780
                    A+ E +  ++T     ++++TA    +    +  T  +L K   A   +I  
Sbjct: 1241 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTK---ATDVSIQP 1297

Query: 781  VINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVG 824
            + NTP    +  GT  +A   +      D  +   SA SH+  G
Sbjct: 1298 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTA---SAASHTVPG 1338



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 137/699 (19%), Positives = 257/699 (36%), Gaps = 46/699 (6%)

Query: 14  SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
           ++V+          ST    T++ +   + T  +S    +  T +   SQ    S+   +
Sbjct: 5   TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE 64

Query: 74  DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
               S  GS++      GS      S    E+  ST+G +   +S TG+    ++A    
Sbjct: 65  ITTTSTAGSENTTVSSAGSG-TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 134 TMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGR------SSGDE 187
           T   +  S+      T G+  T  + V  +   +  A     + S  G       ++G E
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE 183

Query: 188 SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV-TVTSRSATLGKIPKSSALVS 246
           +  P  + S T T   ++ G +  + S  G    TAS   + T+ ++T+G    S     
Sbjct: 184 TITPSTAGSETTT--VSTAGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKV 237

Query: 247 RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
            +AG ++++  A ++        S TN  +    + + +++       +ST+  +  ++S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 307 KSAGLPVPKLR---EPSKTALGSSLPGLV----NQTDKEKGISSDNESVASCNSVKVNPA 359
                         E +K +  SS    V    ++T +   + S+  +V++  S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS--ETTT 355

Query: 360 AQPVSSPAQTSLQPGAKYPDVA---SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHA 416
           A  + S   T    G++    +   S T      G     V    +E    S+  S    
Sbjct: 356 ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTT 415

Query: 417 TMTQQGNLDSPSGS---GVLSSGSSSPLYSKNVDLNQSPLASSPSS----AHSAPSNSLT 469
           T T+   + + S +      +S   S +   +   +++  AS+  S      +A S + T
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475

Query: 470 WGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP 529
             T  S ++  S  GL   +V ++ +   +     S     S   S     S++    T 
Sbjct: 476 AYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTT 535

Query: 530 FVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
              T S  TT+S +   L+  T   +G      S++ T         + S  G   TAA+
Sbjct: 536 VSTTGSETTTVSTTG--LETTTTSTEG------SEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 590 SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFR 649
           +  S  ++V++        S   S TT    + S  T   T S           T+    
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS----TEGSET 643

Query: 650 NSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSS 688
            +  + D ++  +S +GS R       GS  + VS+T S
Sbjct: 644 TTVSTTDSETTMVSTTGSERT-ITSTEGSETTTVSATGS 681



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 116/635 (18%), Positives = 229/635 (36%), Gaps = 60/635 (9%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++VS+  S+TI           +S +    T  +S +  +  T + + S+    
Sbjct: 817  TTASETTTVSTAGSETI----------PASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S  S +    +  GS++      GS+     ++ S+ +  ST G +   +S TGS     
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            + +   T   T  S     L T  T  ++   VS +G  +   + +  S +    ++G E
Sbjct: 927  STEGSET---TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM-GSETTTASTAGSE 982

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247
            +     + S T TA+          GS       T S  T  S + T       + + S 
Sbjct: 983  TTTVSTAGSETTTASI--------EGSETTTVSSTGSETTTVSTTGT------ETTITST 1028

Query: 248  SAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSK 307
                 +++  A ++        S T            + S  G+   + +++     ++ 
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETT-----------TTSTEGSETTTVSTTGSETTTAS 1077

Query: 308  SAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPA 367
            +A L    +         +S  G    T    G  +   S     +  V+  +   ++ +
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTAS 1137

Query: 368  QTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSP 427
             T  +    +  V+  T     G + T     A +E    S   S      T      + 
Sbjct: 1138 TTGSEMTTVFTTVSETTTVSTIGSEATTS-SAAGSEATTTSTEGSETTTASTAGSETTTA 1196

Query: 428  SGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGF 487
            S +G  ++ +S+     N         S+PSSA S  + +   G+  + +S  S +    
Sbjct: 1197 STAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTA- 1255

Query: 488  QSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHL 547
             S++   T+  SI  S ++    + +S+T ++  + D S+ P   T    T  + +    
Sbjct: 1256 TSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA 1315

Query: 548  DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGG--LQDTAANSPFSSGSSVTSPSGTR 605
              +     G+ +T ++             SH+  G  L  +   +     SS TS  G R
Sbjct: 1316 SSSVTMAPGMDFTASA------------ASHTVPGIVLNTSGLGTSTMGASSTTSAHGVR 1363

Query: 606  FNFSQLASPTTVT-----QMSLSNPTMLRTHSLSN 635
                    PT+ T      +S+   T+  +H+ +N
Sbjct: 1364 TTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTN 1398



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 150/814 (18%), Positives = 302/814 (37%), Gaps = 77/814 (9%)

Query: 6   NLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVE 65
           N T+  +++  S+  S+T   +ST    T+++ ++ + T A+S    ++ T     S+  
Sbjct: 127 NSTTSSETTVTSTAGSETT-TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185

Query: 66  RNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR 125
             S    +    S  GS++      GS+     +  S+ +  ST G +   +S  GS   
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 126 GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
             TA    T   T+ S          T  T+D+K +       + +    + S+   +S 
Sbjct: 246 VSTAGSETTAASTEDS-------ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 186 DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALV 245
             S+  + S+    T   ++   +  +  AAG   I AS  TV S + T+      +   
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS--TVGSETTTVSTTGSETTTA 356

Query: 246 SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI-DSNI 304
           S   G ++S D     +      S+  +    +    S++ + +  G+ ++T SI DS  
Sbjct: 357 S-IMGSETSTDSTTGSET--TTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 305 S------SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKE------KGISSDNESVASCN 352
           +      S+   +        + +  GS +  + + +D E      +G  +   + A   
Sbjct: 414 TTTCTEGSEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT------KQVPIATAENMK 406
           +          ++ + T L+    +   +  T     G + T       ++   + E  +
Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 407 NSVVISNPHATMT-------------------------QQGNLDSPSGSGVL---SSGSS 438
           N+ V +    T T                          +   DS  GSG     ++GS 
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 439 SPLYS--KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTS 496
           +   S   + +   S   S  +SA +  S + T  T +S ++  S +G    +VS+  + 
Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 497 CESIDISLSSGGVPS-HNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKK 555
              +  + S   + S   S T  ++++  ++      + +   +++ S+      T  + 
Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSET 712

Query: 556 GLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPT 615
            +  T  S++ T         + S  G + T A++  S  +S ++        S  +S T
Sbjct: 713 TITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772

Query: 616 TVTQMSLSNPTML-----RTHSLSNADGQYDP-YTDSRFRNSSMSLDEKSRTMSRSGSFR 669
           T+  +  S  TM       T  +S A  +    +T++     + +   ++ T+S +GS  
Sbjct: 773 TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-- 830

Query: 670 DGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLV 729
              E +  S+    S T++  ST   +  +   +      AS E     T     +    
Sbjct: 831 ---ETIPASTAG--SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 730 AAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKT 763
           A+ E S    T    S T TA  + SE+  +  T
Sbjct: 886 ASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 919



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 132/750 (17%), Positives = 276/750 (36%), Gaps = 68/750 (9%)

Query: 4   PRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQ 63
           P   ++    ++++S I      +ST     ++  ++ + T  +S    +  T +   S+
Sbjct: 293 PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSE 352

Query: 64  VERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
               S+   +    S  GS++      GS+     ++ S+ +  ST+G +   +S T S 
Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS- 411

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRS 183
               T   G  M     +A +  +    T  T+ ++++         +    S +    +
Sbjct: 412 ETTTTCTEGSEM-----TAVSTTVFETTTASTEGSEIT--------IASTSDSETTTAST 458

Query: 184 SGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSA 243
            G E+     + S T TA         ++ +A+   + T +  T+ S + T       + 
Sbjct: 459 EGSETTTVTTAGSETKTAYTTG----SETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 244 LVSRSAGRKS--SMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
            VS +    +  S +G++N        S  T +    L   + S   +     S+T +  
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTG-SETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 302 SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
           +  S++ +G           T + ++       ++     ++D+E+ ++  +      A 
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTA------DSENTTASTADSETTSASTTGSETTTAS 627

Query: 362 PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVV-ISNPHATMTQ 420
             SS   T+   G++   V++             +  I + E  + + V  +    T++ 
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVST 687

Query: 421 QG------NLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNA 474
           +G      ++     + V ++GS + + S           S  ++A    S + T  T  
Sbjct: 688 EGSGTTTVSITGSETTKVSTTGSETTITSTE--------GSEITTASITGSETTTASTEG 739

Query: 475 SSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTN 534
           S ++  S +  G ++ S+  T  E+   S +S    S  +   ++ S    + T    T 
Sbjct: 740 SETTTASTE--GSETTSASTTGSETTTASTTS----SETTMASIMGSETTMASTIGSETT 793

Query: 535 SVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSS 594
            V T  S+       N+  +  +  T  S+  T   A       S  G + T   S   S
Sbjct: 794 KVSTASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 595 GSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMS 654
            ++  S  G+    +   S  T T  ++ + T     + ++ +G     T +    ++ +
Sbjct: 852 ETTTASTEGSETTTASTESSETTTATTIGSET-----TTASTEGSETTTTSTEGSETTTA 906

Query: 655 LDEKSR--TMSRSGS-----FRDGFE----EVHGSSLSLVSSTSS--VYSTPEEKCQSEI 701
             E S   T+S +GS       +G E       GS L+ VS+T S  +  + E    + +
Sbjct: 907 STEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTV 966

Query: 702 RKLRRELDASQEKVSALTTQLTANAHLVAA 731
             +  E   +    S  TT  TA +    A
Sbjct: 967 TTMGSETTTASTAGSETTTVSTAGSETTTA 996



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 113/591 (19%), Positives = 218/591 (36%), Gaps = 42/591 (7%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++ +S         ST+   T+++ +  + T  ++    +  T + + S+    
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT 896

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S    +    S  GS+       GS+     ++ S+ +  ST G +   +S TGS    +
Sbjct: 897  STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            +A+   T   T  +       T  T  ++   VS  G  +  AS ++ S +    S+G E
Sbjct: 957  SAEGSET---TTVTTMGSETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVSSTGSE 1012

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAG---LAMITASGVTVT-----SRSATLGKIP 239
            +     S++ T T   ++ G +  + + AG    A+ T    T T     S + T+    
Sbjct: 1013 T--TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              +   S +    +++  + +         S T   Y +  + + +++        ST+S
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 300  IDSNISSKSAGLPVPKLREPSKT---------ALGSSLPGLVNQTDKEKGISSDNESVAS 350
             ++  +S +           S+T         A  SS  G    T   +G  +   S A 
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 351  CNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVV 410
              +   + A    ++ A TS           S T      G  T    I  +E    S  
Sbjct: 1191 SETTTASTAGSETTT-ASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTA 1249

Query: 411  ISNPHATMTQQGNLD----SPSGSGVLSSGSSSPLY--SKNVDLNQSPLASSPSSAHSAP 464
               P AT            + SG+   S+  SS  +  +K  D++  P+ ++P S     
Sbjct: 1250 SLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTT 1309

Query: 465  SNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKD 524
               LT     +SSS     G+ F + ++ HT      I L++ G+ +         S+  
Sbjct: 1310 GTRLT-----ASSSVTMAPGMDFTASAASHT---VPGIVLNTSGLGTSTMGASSTTSAHG 1361

Query: 525  DSLTPFVRTNSVKTTLSESDP-HLDRNTLPKKGLRYTPTSQLRTQEDAKEW 574
               T         +T  E+ P  +  NT+    + +TPT+ ++     + W
Sbjct: 1362 VRTTTGSTREPTSSTFQETGPVSMGTNTV---SMSHTPTNVIKPSGYLQPW 1409



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 122/638 (19%), Positives = 231/638 (36%), Gaps = 62/638 (9%)

Query: 5    RNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQV 64
            R +TS + S + +   + +   +ST+   T++   + + T   S    +    + + S++
Sbjct: 663  RTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEI 722

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWR 124
               S+   +    S  GS++      GS+     +  S+ +  ST+  +  + S  GS  
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS-E 781

Query: 125  RGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSS 184
              M + +G     TK S  +  + T  T  ++    S              S +    ++
Sbjct: 782  TTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS-----------TTASETTTVSTA 828

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
            G E+     + S T T  +   G +  + S  G    TAS  +  + +AT      ++A 
Sbjct: 829  GSETIPASTAGSETTTTTSTE-GSETTTASTEGSETTTASTESSETTTATTIGSETTTAS 887

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSN- 303
               S    +S +G++                  +    S+  + +  G+ ++T+S + + 
Sbjct: 888  TEGSETTTTSTEGSETT---------------TASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 304  -ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQP 362
              ++ + G  +  +       +  S  G    T    G  +   S A   +  V+ A   
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA--- 989

Query: 363  VSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQG 422
              S   T+   G++   V+S        G  T  V     E    S   S    T+T  G
Sbjct: 990  -GSETTTASIEGSETTTVSST-------GSETTTVSTTGTETTITSTEGSET-TTVTTAG 1040

Query: 423  NLDSPSGSGVLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAV 480
            +      + V ++GS +   S   +     S   S  ++A +A   + T  T+ S ++  
Sbjct: 1041 S----ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTA 1096

Query: 481  SKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTL 540
            S  G    +V    +   +     S     S  SS    AS+    +T    T S  TT+
Sbjct: 1097 STAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTV 1156

Query: 541  SESDPHLDRNTLPKKGLRYTPT--SQLRTQEDAKEWLRSHSAGGLQDTAA-------NSP 591
            S        ++        T T  S+  T   A     + S  G + T A       N+ 
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTA 1216

Query: 592  FSSGSSVTSPS--GTRFNFS-QLASPTTVTQMSLSNPT 626
             ++GS  ++PS  G+  N +  + S TT+   +   PT
Sbjct: 1217 CTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPT 1254



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 123/739 (16%), Positives = 258/739 (34%), Gaps = 77/739 (10%)

Query: 173 VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRS 232
           +K S +    ++G E+  P P+ S+T   + +  G +  + S AG    T S        
Sbjct: 30  IKASETTTASTAGSETTTPSPTGSQTTIVSIS--GSEITTTSTAGSENTTVSS---AGSG 84

Query: 233 ATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAG 292
            T   +  S   VS +    +++     +     A+ S T     +    S++   + AG
Sbjct: 85  TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTT---SSETTVTSTAG 141

Query: 293 NRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCN 352
           + ++T S        + G               +S  G    T    G  +   S A   
Sbjct: 142 SETTTVS--------TVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412
           +  V+ A    ++ + T  +        +  T     G + TK   ++TA    +   +S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK---VSTA---GSETTVS 247

Query: 413 NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGT 472
              +  T     DS + +       ++   +   +       ++ S+  S P+ + T G+
Sbjct: 248 TAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE------TTAASTTGSEPTMASTMGS 301

Query: 473 NASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVR 532
             + +S +  +       + + T+   +    ++G      S+ G               
Sbjct: 302 ETTMASTIGPE------TTKVSTASSEVTTVFAAGSETIRASTVG-------------SE 342

Query: 533 TNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPF 592
           T +V TT SE+       T    G      S+  T         + S  G + T A++  
Sbjct: 343 TTTVSTTGSET------TTASIMG------SETSTDSTTGSETTTASTEGSETTTASTEG 390

Query: 593 SSGSSVTSPSGTRFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSNADGQYDPYTDSR 647
           S  ++V++        S   S TT T     +M+  + T+  T + S    +    + S 
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 648 FRNSSMSLD-EKSRTMSRSGS-----FRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEI 701
              ++ S +  ++ T++ +GS     +  G E    S+  L ++T     +      +E 
Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG 510

Query: 702 RKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDS---ELN 758
            +    + A+  +++ ++T+ + N  +     ++    T  L++ T + E  +       
Sbjct: 511 SE-TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569

Query: 759 ELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSAT 818
               T +  +     A +       T       N TA +AD       ++ S ++  S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629

Query: 819 SHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLP 878
           S  +  ++ E             ++     G   S ++ +S    E  T S+  S   + 
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTG---SERTITSTEGSETTTVSATGSETTVS 686

Query: 879 HNGSTGSTPLLRNSHSNSL 897
             GS  +T  +  S +  +
Sbjct: 687 TEGSGTTTVSITGSETTKV 705


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 233/1093 (21%), Positives = 414/1093 (37%), Gaps = 138/1093 (12%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINT----SSSISSYANTPASSRKNLDVQTDAEKHSQ 63
            T+ D +S  +S  S+    L++  ++T    SS  ++ + TP  S+  +   T+A   + 
Sbjct: 1556 TTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTT 1615

Query: 64   VERNSLW-----SGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVIS 118
             E +S+       G  +  S   S + +     S     P D +     ST    +P  +
Sbjct: 1616 AEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPA 1675

Query: 119  Q-----TGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDA---KVSEKGRLSPKA 170
            +     T ++  G T    IT+ RT P A + A+ T  T   D++     S + R SP  
Sbjct: 1676 EGTSMPTSTYTEGRTPLTSITV-RTTPVA-SSAISTLSTTPVDNSTPVTTSTEARSSPTT 1733

Query: 171  SQVKRSPSDAGRSSGDESKKPLPS---------SSRTPTANANSFGFKK--QSGSAAGLA 219
            S+    P+    S+  E   PL S         SS   T +A          + + A  +
Sbjct: 1734 SEGTSMPN----STPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSS 1789

Query: 220  MITASGVTVTSRSATLGKIPKSSALVSRS--AGRKSSMDGAQNQDDGYLALSSRTNLQYR 277
              TA G ++ + + + G  P +S  VS +  A  ++S       D     +   T+    
Sbjct: 1790 PTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVV---TSTAVS 1846

Query: 278  SLPRPSK----SNSRNGAGNRSSTS---------SIDSNISSKSAGL---PVPKLREPSK 321
            S P P++    + S    G+ + TS         S ++N  S +  +   PV    + S 
Sbjct: 1847 SSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSS 1906

Query: 322  ---TALGSSLPGLVNQTDKE-----KGISSDNESVASCN----SVKVNPAAQPVSSPAQT 369
               TA GSS+P     T +E       I     +VAS      S  +     PV++ +Q 
Sbjct: 1907 SPTTADGSSMP---TSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQA 1963

Query: 370  SLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSG 429
            S  P       + PT     G  P   +P++T      ++V+S+  +T++    +D+ + 
Sbjct: 1964 SSSP-TTADGTSMPTPAYSEGSTPLTSMPLST------TLVVSSEASTLSTT-PVDTSTP 2015

Query: 430  SGVLSSGSSSPLYSKNVDLNQS-------PLASSPSSAHSAPSNSLTWGTNASSSSAVSK 482
            +   + GSSSP  +    +  S       PLA  P S     S+    G   S++   SK
Sbjct: 2016 ATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSE---GNTLSTTPVDSK 2072

Query: 483  DGLGFQSVSSLHTSCE--SIDISLSSGGVPSHNS---STGLIASSKDDSL-TPFVRTNSV 536
              +   + +S   + E  S+ IS  S G P   S   ST  +AS +  +L T  V +NS 
Sbjct: 2073 TQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSP 2132

Query: 537  KTTLSESDPHLDRNTLPKKG--LRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSS 594
              T +E    +  + +P +G  ++ +  S  RT   +     +  A     T + +P  +
Sbjct: 2133 VITSTE----VSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDT 2188

Query: 595  GSSVTSPSGTRFNFSQLASPTTV--TQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSS 652
             + VT+ +  R      +SPTT   T M  S P+   T   ++      P   S     S
Sbjct: 2189 STPVTNSTEAR------SSPTTSEGTSMPTSTPSEGST-PFTSMPVSTMPVVTSEASTLS 2241

Query: 653  MSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQ 712
             +  + S  ++ S           G+S+   +ST S  +TP          +   L A+ 
Sbjct: 2242 ATPVDTSTPVTTSTEATSSPTTAEGTSIP--TSTLSEGTTPLTSI-----PVSHTLVANS 2294

Query: 713  EKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSL-TMTAEQKDSELNELRKTIELLKKQN 771
            E  +  TT + +N     + E S    T    S+ T T+ + ++ L  +  +  ++    
Sbjct: 2295 EVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFE 2354

Query: 772  AAAQAAINGVINTP--ELNCKGNGTAQSADLRIRRQHSSDS--------VSSINSATSHS 821
             +  +      +TP    +  G+    + D  +     S+         VS++   +S +
Sbjct: 2355 TSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEA 2414

Query: 822  SVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNG 881
            S  S    D+      +   SS          P S  S      +    + ++P +    
Sbjct: 2415 STHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEG-TTPLASMPVSTTPVVSSEA 2473

Query: 882  STGSTPLLRNSHSNSLISECMDS--EAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQ 939
             T ST  +  S   +  +E   S   AE ++   +   +    LT I +     A     
Sbjct: 2474 GTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASP--- 2530

Query: 940  LREAMNRMQSEIEK---LKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNL 996
              EA     + ++    +    +   S +   G S   S  S  ++P +SM +S   L  
Sbjct: 2531 --EASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLAS 2588

Query: 997  TESTSLDMLLDDT 1009
            +E+++L     DT
Sbjct: 2589 SEASTLSTTPVDT 2601



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 159/745 (21%), Positives = 277/745 (37%), Gaps = 116/745 (15%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINT----SSSISSYANTPASSRKNLDVQTDAEKHSQ 63
            T+ +D+S  +S  S+    L++  ++T    SS  S+ + TP  S+  +   T+A     
Sbjct: 435  TTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPP 494

Query: 64   V-ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGS 122
              E NS+ +    + S   +   +   P +         S+ S  ST+    PV + T  
Sbjct: 495  TAEVNSMPTSTPSEGSTPLTSMSVSTMPVAS--------SEASTLSTT----PVDTSTP- 541

Query: 123  WRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTD--DAKVSEKGRLSPKASQVKRSPSDA 180
                +T     +   T P   +    TP  G T   +  VS +  +S +AS    +P+D+
Sbjct: 542  ----VTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADS 597

Query: 181  GRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSA-TLGKIP 239
                   S+    +SS + TA   S      S     +  ++ S   V S  A TL   P
Sbjct: 598  NTFVTTSSE----ASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTP 653

Query: 240  -KSSALVSRSAGRKSSMDGAQNQD-------DGYLALSS---RTNLQYRS---------- 278
              S+  V+ S    SS   A+          +G   L+S    T L   S          
Sbjct: 654  VDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPV 713

Query: 279  ------LPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLV 332
                        S+S   A   S  +S  S  S+    +PV      SKT L SS    +
Sbjct: 714  DTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPV------SKTLLTSSEASTL 767

Query: 333  NQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGK 392
            + T  +        + ASC+       + P+S+P++             SP L  +    
Sbjct: 768  STTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSE------------GSPLLTSI---- 811

Query: 393  PTKQVPIAT--AENMKNSVVISN-PHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLN 449
            P    P+ +  A  +  + V SN P  T T+  +  +P      + G+S P  +      
Sbjct: 812  PVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTP------AEGTSMP--TSTYSEG 863

Query: 450  QSPLASSP-----------SSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCE 498
            ++PL S P           S+  + P ++ T  TN++ + +      G    +S      
Sbjct: 864  RTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGS 923

Query: 499  SIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLR 558
            +   S+     P  +S    ++++  D+ TP   +    ++ + ++      + P +G  
Sbjct: 924  TPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEG-- 981

Query: 559  YTPTSQLRTQEDAKEWLRSHSAGGLQDTA--ANSPFSSGSSVTSPSGTRFNFSQLAS--- 613
               T+ L +   +   + +  A  L  T   +N+P ++ +  +SP  T    S   S   
Sbjct: 982  ---TTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPS 1038

Query: 614  --PTTVTQMSLSNPTM----LRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGS 667
               T +T+M +S   +      T S + AD      T S+  +SS + D  S   S    
Sbjct: 1039 EGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSE 1098

Query: 668  FRDGFEEVHGSSLSLVSSTSSVYST 692
                   V  S+  +VSS +S  ST
Sbjct: 1099 GSTPLTSVPVSTRLVVSSEASTLST 1123



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 150/732 (20%), Positives = 277/732 (37%), Gaps = 93/732 (12%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+ + +S  +S  S+    L++  ++T+  +SS A T +++   +D  T     ++   +
Sbjct: 2439 TTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTP--VDTSTPMTTSTEAS-S 2495

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTS--GKKNPVISQTGSWRR 125
            S  + +D+      +  G  +         P    + S  ST+     +PV++ T     
Sbjct: 2496 SPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSS 2555

Query: 126  GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
              +A+ G +MP +  S  +  L++          VS K   S +AS +  +P D      
Sbjct: 2556 ATSAE-GTSMPTSTYSEGSTPLRS--------MPVSTKPLASSEASTLSTTPVDTSIPVT 2606

Query: 186  DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSA-TLGKIPKSS-A 243
              ++    +SS   TA   S      S  +  L  I  S + V S  A TL   P  +  
Sbjct: 2607 TSTE----TSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRT 2662

Query: 244  LVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSN 303
            LV+ S G  SS   A+           R+      L   S +   N   +  ST+ +D++
Sbjct: 2663 LVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILV--STTLLANSEASTLSTTPVDTS 2720

Query: 304  --ISSKSAGLPVPKLRE--------------PSKTALGSSLP------GLVNQTDKEKGI 341
              +++ +     P   E              P  + L S+LP        V+ T  +  I
Sbjct: 2721 TPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSI 2780

Query: 342  SSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIAT 401
                 + AS +       + P S+P++TS                      P    P+A+
Sbjct: 2781 PVTTSTEASSSPTTAEVTSMPTSTPSETSTP----------------LTSMPVNHTPVAS 2824

Query: 402  AE--NMKNSVVISNPHATMTQQGNLDSPSGSGV---LSSGSSSPLYSKNVDLNQSPLASS 456
            +E   +  + V ++   T + + +    +  G+   +S+ S       ++ ++ +P+ASS
Sbjct: 2825 SEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASS 2884

Query: 457  PSSAHSA----PSNSLTWGTNASSSSAVSK-DGLGFQSVSSLHTSCESIDISLSSGGVPS 511
             +S  S      S  +T  T  SSS   ++   +   + S + T   SI +S     VP 
Sbjct: 2885 EASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVST----VPV 2940

Query: 512  HNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDA 571
              S    ++++  D+ TP   T S + + S +        +   G R TP + +      
Sbjct: 2941 AGSEASTLSTTPVDTRTPV--TTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMP 2998

Query: 572  KEWLRSHSAGGLQDTAAN------SPFSSGSSVTSPSGTRFNF---SQLASPTTVTQMSL 622
               + S  A  L  T A+      +   + SS T+  GT       S+ ++P T   +S 
Sbjct: 2999 ---VASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVST 3055

Query: 623  SNPTMLRTHSLSN--ADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSL 680
            +   +    +LS    D      T +   +S    +  S  +S   ++ +G   + G  +
Sbjct: 3056 TPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPIS---TYSEGSTPLTGVPV 3112

Query: 681  SLVSSTSSVYST 692
            S    TSS  ST
Sbjct: 3113 STTPVTSSAIST 3124



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 153/714 (21%), Positives = 264/714 (36%), Gaps = 122/714 (17%)

Query: 149 TPGTGKTDDAKVSEKGRLSPKASQVKRSPS-----DAGRSSGDE----SKKPLPSSSRTP 199
           TP   +T     S+   L P +++   SP+     D   S+  E    S     S++  P
Sbjct: 111 TPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLP 170

Query: 200 TANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQ 259
           +  A +    K   S        AS    T  S T+ K   S      ++   S+M  A 
Sbjct: 171 SFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVAS 230

Query: 260 NQDDGYLA----------LSSRTNLQYRSLPRPSKSNSRNGAGNRSST----------SS 299
           ++    L           +S++ +    +   PS SNS    G+   T          SS
Sbjct: 231 SEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSS 290

Query: 300 IDSNISSKSAGLPVPKLREPSK-----TALGSSLPGLVNQTDKEKGISSDNES------- 347
             S +S+  A   +P +          TA G+S+P     T+    ++S   S       
Sbjct: 291 EASTLSTTPAATNIPVITSTEASSSPTTAEGTSIP-TSTYTEGSTPLTSTPASTMPVATS 349

Query: 348 -VASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMK 406
            +++ +   V+ +    +S   +SL   A+   + + TL    G  P   +P++T     
Sbjct: 350 EMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSE--GSTPLTNMPVST----- 402

Query: 407 NSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDL-------NQSPLASSPSS 459
             +++++  A+ T    +DS +     S  SSSP  +++  +         +PL S P S
Sbjct: 403 --ILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVS 460

Query: 460 ----AHSAPSN----------SLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESID---- 501
               A S  SN           +T  T ASSS   ++       V+S+ TS  S      
Sbjct: 461 TTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAE-------VNSMPTSTPSEGSTPL 513

Query: 502 ISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKG---LR 558
            S+S   +P  +S    ++++  D+ TP   ++   ++ +  +      + P +G   L 
Sbjct: 514 TSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLT 573

Query: 559 YTPTS-----------QLRTQEDAKEWLRSHSAGGLQDTAA---NSPFSS----GSSVTS 600
             P S              T  D+  ++ + S      T A   + P S+    G+++TS
Sbjct: 574 NMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITS 633

Query: 601 PS-GTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSN---ADGQYDP---YTDSRFRNSSM 653
            S  T    S  AS  + T +  + P    T + S+   A+G   P   YT+     +SM
Sbjct: 634 MSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSM 693

Query: 654 ----SLDEKSRTMSRSGSFRDGFEEV-----HGSSLSLVSSTSSVYSTPEE-KCQSEIRK 703
               +L   S   + S +  D    V       SS +     S   STP E         
Sbjct: 694 PVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMP 753

Query: 704 LRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSEL 757
           + + L  S E  +  TT L  + H+  + E S    T    S+ ++   + S L
Sbjct: 754 VSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPL 807



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 162/781 (20%), Positives = 293/781 (37%), Gaps = 117/781 (14%)

Query: 7    LTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVER 66
            ++++ + S+  +G+      +ST  + TSS+IS+ + TP  +  +  V T  E HS    
Sbjct: 3097 ISTYSEGSTPLTGVP-----VSTTPV-TSSAISTLSTTPVDT--STPVTTSTEAHSSPTT 3148

Query: 67   NSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRG 126
            +   S      S+G +   +   P S      S+ S  S         PV + T +    
Sbjct: 3149 SEGTSMPTSTPSEGSTP--LTYMPVSTMLVVSSEDSTLSATPVD-TSTPVTTSTEA--TS 3203

Query: 127  MTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGD 186
             T   G ++P + PS         G        VS     S +AS +  +P D+      
Sbjct: 3204 STTAEGTSIPTSTPSE--------GMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTT 3255

Query: 187  ESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTV-TSRSATLGKIPKSSALV 245
             ++    +SS  PTA   S      S  +  L  +  S  TV +S ++TL   P  ++  
Sbjct: 3256 STE----ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTP 3311

Query: 246  SRSAGRKSSM----DGAQNQDDGYLALSSR-TNLQYRSLPRPSKSNSRNGAGNRSSTSSI 300
              +  + SS     DG       Y   S+  TN+ + + P  S   S        ST+ +
Sbjct: 3312 VTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEAST------LSTTPV 3365

Query: 301  DSNISSKSAGLPVPKLREPS---KTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVN 357
            D++        PV    E S    TA G+S+P   + ++    ++S   S     S +VN
Sbjct: 3366 DTST-------PVTTSTEASLSPTTAEGTSIP-TSSPSEGTTPLASMPVSTTPVVSSEVN 3417

Query: 358  P-AAQPV-SSPAQTSLQPGAKYPDVAS----PTLRRLFGGKPTKQVPIATAENMKNSVVI 411
              +  PV S+   T+    +  P +A     PT     G  P   +P++T          
Sbjct: 3418 TLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLST---------- 3467

Query: 412  SNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAH--SAPSNSLT 469
                          +P  S   S+ S++P+ +       SP  SSP++A   S P+++  
Sbjct: 3468 --------------TPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAG 3513

Query: 470  WGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP 529
             G+   ++  VS   +     S+L T+    +  ++S    S + +T  + + +    TP
Sbjct: 3514 EGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMR--MSTP 3571

Query: 530  FVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
               ++S+ T L  S               Y  +S+  T           S      T +N
Sbjct: 3572 SEGSSSLTTMLLSS--------------TYVTSSEASTPSTPSV---DRSTPVTTSTQSN 3614

Query: 590  SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLR--THSLSNADGQYDPYTDSR 647
            S  +    +T P  T    S++++P T+  +S ++ T+    T S    D      T ++
Sbjct: 3615 STPTPPEVITLPMSTP---SEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQ 3671

Query: 648  FRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRE 707
              +S ++ +  +  +            +  S+  + SS  S  STP     + +      
Sbjct: 3672 VSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEA 3731

Query: 708  LDASQE------------KVSALTTQLTANAHLVAAF-EQSLGNMTIRLQSLTMTAEQKD 754
            + +S              ++S L T +  +   V  F E S  ++     S++MT   + 
Sbjct: 3732 ISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEG 3791

Query: 755  S 755
            S
Sbjct: 3792 S 3792



 Score = 34.7 bits (78), Expect = 0.71
 Identities = 94/474 (19%), Positives = 167/474 (35%), Gaps = 53/474 (11%)

Query: 451 SPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVP 510
           +P  S  +S  ++ S +L   +   +SS  + +G      +    S  S    +S+  +P
Sbjct: 111 TPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLP 170

Query: 511 SHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQED 570
           S  + T L  + K D  TP   T S + + S + P  +  T+PK            T  +
Sbjct: 171 SFEAYTSL--TYKVDMSTPL--TTSTQASSSPTTP--ESTTIPKS-----------TNSE 213

Query: 571 AKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRT 630
               L S  A  ++  ++ +     + +T+P        ++++P T++  + S+PT    
Sbjct: 214 GSTPLTSMPASTMKVASSEAI----TLLTTPV-------EISTPVTISAQASSSPTTAEG 262

Query: 631 HSLSNA--DGQYDPYTDSRF--------RNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSL 680
            SLSN+   G   P T              S++S    +  +    S             
Sbjct: 263 PSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGT 322

Query: 681 SLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMT 740
           S+ +ST +  STP     +    +      S+    ++T   T+     +    SL    
Sbjct: 323 SIPTSTYTEGSTPLTSTPASTMPVA----TSEMSTLSITPVDTSTLVTTSTEPSSLPTTA 378

Query: 741 IRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAI----NGVINTPELNCKGNGTAQ 796
                LT T  +  + L  +  +  L+    A+  + I       + T         TA+
Sbjct: 379 EATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAE 438

Query: 797 SADLRIRRQH------SSDSVSSINSATSHSSVGSNIESDSKKKKRKNWLRSSFKQAFGK 850
              +            +S  VS+   A+S +S  S    DSK +   +   SS       
Sbjct: 439 DTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEV 498

Query: 851 KKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDS 904
              P S  S      +T  S+ + P      ST ST  +  S   +  SE   S
Sbjct: 499 NSMPTSTPSEGS-TPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSS 551


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 137/699 (19%), Positives = 257/699 (36%), Gaps = 46/699 (6%)

Query: 14  SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
           ++V+          ST    T++ +   + T  +S    +  T +   SQ    S+   +
Sbjct: 5   TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE 64

Query: 74  DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
               S  GS++      GS      S    E+  ST+G +   +S TG+    ++A    
Sbjct: 65  ITTTSTAGSENTTVSSAGSG-TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 134 TMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGR------SSGDE 187
           T   +  S+      T G+  T  + V  +   +  A     + S  G       ++G E
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE 183

Query: 188 SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV-TVTSRSATLGKIPKSSALVS 246
           +  P  + S T T   ++ G +  + S  G    TAS   + T+ ++T+G    S     
Sbjct: 184 TITPSTAGSETTT--VSTAGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKV 237

Query: 247 RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
            +AG ++++  A ++        S TN  +    + + +++       +ST+  +  ++S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 307 KSAGLPVPKLR---EPSKTALGSSLPGLV----NQTDKEKGISSDNESVASCNSVKVNPA 359
                         E +K +  SS    V    ++T +   + S+  +V++  S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS--ETTT 355

Query: 360 AQPVSSPAQTSLQPGAKYPDVA---SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHA 416
           A  + S   T    G++    +   S T      G     V    +E    S+  S    
Sbjct: 356 ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTT 415

Query: 417 TMTQQGNLDSPSGS---GVLSSGSSSPLYSKNVDLNQSPLASSPSS----AHSAPSNSLT 469
           T T+   + + S +      +S   S +   +   +++  AS+  S      +A S + T
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475

Query: 470 WGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP 529
             T  S ++  S  GL   +V ++ +   +     S     S   S     S++    T 
Sbjct: 476 AYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTT 535

Query: 530 FVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
              T S  TT+S +   L+  T   +G      S++ T         + S  G   TAA+
Sbjct: 536 VSTTGSETTTVSTTG--LETTTTSTEG------SEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 590 SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFR 649
           +  S  ++V++        S   S TT    + S  T   T S           T+    
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS----TEGSET 643

Query: 650 NSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSS 688
            +  + D ++  +S +GS R       GS  + VS+T S
Sbjct: 644 TTVSTTDSETTMVSTTGSERT-ITSTEGSETTTVSATGS 681



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 113/636 (17%), Positives = 227/636 (35%), Gaps = 52/636 (8%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++VS+  S+TI           +S +    T  +S +  +  T + + S+    
Sbjct: 817  TTASETTTVSTAGSETI----------PASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S  S +    +  GS++      GS+     ++ S+ +  ST G +   +S TGS     
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            + +   T   T  S     L T  T  ++   VS +G  +   + +  S +    ++G E
Sbjct: 927  STEGSET---TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM-GSETTTASTAGSE 982

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247
            +     + S T TA+          GS       T S  T  S + T       + + S 
Sbjct: 983  TTTVSTAGSETTTASI--------EGSETTTVSSTGSETTTVSTTGT------ETTITST 1028

Query: 248  SAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID-SNISS 306
                 +++  A ++        S T          +  ++       +ST+ ++ + +S+
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 307  KSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSP 366
              +G           T +   + G    T   +G  +   S  S  +   +     +++ 
Sbjct: 1089 SGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT- 1145

Query: 367  AQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDS 426
              T++        + S        G          +E    S   S      T      +
Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTT 1205

Query: 427  PSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLG 486
             S +G  ++ +S+     N         S+PSSA S  + +   G+  + +S  S +   
Sbjct: 1206 ASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTA 1265

Query: 487  FQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPH 546
              S++   T+  SI  S ++    + +S+T ++  + D S+ P   T    T  + +   
Sbjct: 1266 -TSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLT 1324

Query: 547  LDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGG--LQDTAANSPFSSGSSVTSPSGT 604
               +     G+ +T ++             SH+  G  L  +   +     SS TS  G 
Sbjct: 1325 ASSSVTMAPGMDFTASA------------ASHTVPGIVLNTSGLGTSTMGASSTTSAHGV 1372

Query: 605  RFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSN 635
            R        PT+ T      +S+   T+  +H+ +N
Sbjct: 1373 RTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTN 1408



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 150/814 (18%), Positives = 301/814 (36%), Gaps = 77/814 (9%)

Query: 6   NLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVE 65
           N T+  +++  S+  S+T   +ST    T+++ ++ + T A+S    ++ T     S+  
Sbjct: 127 NSTTSSETTVTSTAGSETT-TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185

Query: 66  RNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR 125
             S    +    S  GS++      GS+     +  S+ +  ST G +   +S  GS   
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 126 GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
             TA    T   T+ S          T  T+D+K +       + +    + S+   +S 
Sbjct: 246 VSTAGSETTAASTEDS-------ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 186 DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALV 245
             S+  + S+    T   ++   +  +  AAG   I AS  TV S + T+      +   
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS--TVGSETTTVSTTGSETTTA 356

Query: 246 SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI-DSNI 304
           S   G ++S D     +      S+  +    +    S++ + +  G+ ++T SI DS  
Sbjct: 357 S-IMGSETSTDSTTGSET--TTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 305 S------SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKE------KGISSDNESVASCN 352
           +      S+   +        + +  GS +  + + +D E      +G  +   + A   
Sbjct: 414 TTTCTEGSEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT------KQVPIATAENMK 406
           +          ++ + T L+    +   +  T     G + T       ++   + E  +
Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 407 NSVVISNPHATMT-------------------------QQGNLDSPSGSGVL---SSGSS 438
           N+ V +    T T                          +   DS  GSG     ++GS 
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 439 SPLYS--KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTS 496
           +   S   + +   S   S  +SA +  S + T  T +S ++  S +G    +VS+  + 
Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 497 CESIDISLSSGGVPS-HNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKK 555
              +  + S   + S   S T  ++++  ++      + +   +++ S+      T  + 
Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSET 712

Query: 556 GLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPT 615
               T  S++ T         + S  G + T A++  S  +S ++        S  +S T
Sbjct: 713 TTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772

Query: 616 TVTQMSLSNPTML-----RTHSLSNADGQYDP-YTDSRFRNSSMSLDEKSRTMSRSGSFR 669
           T+  +  S  TM       T  +S A  +    +T++     + +   ++ T+S +GS  
Sbjct: 773 TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-- 830

Query: 670 DGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLV 729
              E +  S+    S T++  ST   +  +   +      AS E     T     +    
Sbjct: 831 ---ETIPASTAG--SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 730 AAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKT 763
           A+ E S    T    S T TA  + SE+  +  T
Sbjct: 886 ASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 919



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 136/748 (18%), Positives = 273/748 (36%), Gaps = 64/748 (8%)

Query: 4   PRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQ 63
           P   ++    ++++S I      +ST     ++  ++ + T  +S    +  T +   S+
Sbjct: 293 PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSE 352

Query: 64  VERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
               S+   +    S  GS++      GS+     ++ S+ +  ST+G +   +S T S 
Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS- 411

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRS 183
               T   G  M     +A +  +    T  T+ ++++         +    S +    +
Sbjct: 412 ETTTTCTEGSEM-----TAVSTTVFETTTASTEGSEIT--------IASTSDSETTTAST 458

Query: 184 SGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSA 243
            G E+     + S T TA         ++ +A+   + T +  T+ S + T       + 
Sbjct: 459 EGSETTTVTTAGSETKTAYTTG----SETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 244 LVSRSAGRKS--SMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
            VS +    +  S +G++N        S  T +    L   + S   +     S+T +  
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTG-SETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 302 SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
           +  S++ +G           T + ++       ++     ++D+E+ ++  +      A 
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTA------DSENTTASTADSETTSASTTGSETTTAS 627

Query: 362 PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQ 421
             SS   T+   G++   V++             +  I + E  + + V +    T    
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV-- 685

Query: 422 GNLDSPSGSG---VLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASS 476
               S  GSG   V  +GS +   S   +     S   S  ++A    S + T  T  S 
Sbjct: 686 ----STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 477 SSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSV 536
           ++  S +  G ++ S+  T  E+   S +S    S  +   ++ S    + T    T  V
Sbjct: 742 TTTASTE--GSETTSASTTGSETTTASTTS----SETTMASIMGSETTMASTIGSETTKV 795

Query: 537 KTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 596
            T  S+       N+  +  +  T  S+  T   A       S  G + T   S   S +
Sbjct: 796 STASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 597 SVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLD 656
           +  S  G+    +   S  T T  ++ + T     + ++ +G     T +    ++ +  
Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGSET-----TTASTEGSETTTTSTEGSETTTAST 908

Query: 657 EKSR--TMSRSGS-----FRDGFE----EVHGSSLSLVSSTSS--VYSTPEEKCQSEIRK 703
           E S   T+S +GS       +G E       GS L+ VS+T S  +  + E    + +  
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968

Query: 704 LRRELDASQEKVSALTTQLTANAHLVAA 731
           +  E   +    S  TT  TA +    A
Sbjct: 969 MGSETTTASTAGSETTTVSTAGSETTTA 996



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 114/600 (19%), Positives = 220/600 (36%), Gaps = 50/600 (8%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++ +S         ST+   T+++ +  + T  ++    +  T + + S+    
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT 896

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S    +    S  GS+       GS+     ++ S+ +  ST G +   +S TGS    +
Sbjct: 897  STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            +A+   T   T  +       T  T  ++   VS  G  +  AS ++ S +    S+G E
Sbjct: 957  SAEGSET---TTVTTMGSETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVSSTGSE 1012

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAG---LAMITASGVTVT-----SRSATLGKIP 239
            +     S++ T T   ++ G +  + + AG    A+ T    T T     S + T+    
Sbjct: 1013 T--TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              +   S +    +++  + +         S T   Y +  + + +++        ST+S
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 300  IDSNISSKSAGLPVPKLREPSKT---------ALGSSLPGLVNQTDKEKGISSDNESVAS 350
             ++  +S +           S+T         A  SS  G    T   +G  +   S A 
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 351  CNSVKVNPA------AQPVSSPAQTSLQPGAKYP---DVASPTLRRLFGGKPTKQVPIAT 401
              +   + A      A    S   T+   G++        S T      G  T    I  
Sbjct: 1191 SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIG 1250

Query: 402  AENMKNSVVISNPHATMTQQGNLD----SPSGSGVLSSGSSSPLY--SKNVDLNQSPLAS 455
            +E    S     P AT            + SG+   S+  SS  +  +K  D++  P+ +
Sbjct: 1251 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITN 1310

Query: 456  SPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSS 515
            +P S        LT     +SSS     G+ F + ++ HT      I L++ G+ +    
Sbjct: 1311 TPMSGTRTTGTRLT-----ASSSVTMAPGMDFTASAASHT---VPGIVLNTSGLGTSTMG 1362

Query: 516  TGLIASSKDDSLTPFVRTNSVKTTLSESDP-HLDRNTLPKKGLRYTPTSQLRTQEDAKEW 574
                 S+     T         +T  E+ P  +  NT+    + +TPT+ ++     + W
Sbjct: 1363 ASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTV---SMSHTPTNVIKPSGYLQPW 1419



 Score = 54.3 bits (129), Expect = 9e-07
 Identities = 158/832 (18%), Positives = 298/832 (35%), Gaps = 96/832 (11%)

Query: 5    RNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQV 64
            R +TS + S + +   + +   +ST+   T++   + + T   S    +  T + + S++
Sbjct: 663  RTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWR 124
               S+   +    S  GS++      GS+     +  S+ +  ST+  +  + S  GS  
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS-E 781

Query: 125  RGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSS 184
              M + +G     TK S  +  + T  T  ++    S              S +    ++
Sbjct: 782  TTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS-----------TTASETTTVSTA 828

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
            G E+     + S T T  +   G +  + S  G    TAS  +  + +AT      ++A 
Sbjct: 829  GSETIPASTAGSETTTTTSTE-GSETTTASTEGSETTTASTESSETTTATTIGSETTTAS 887

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSN- 303
               S    +S +G++                  +    S+  + +  G+ ++T+S + + 
Sbjct: 888  TEGSETTTTSTEGSETT---------------TASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 304  -ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQP 362
              ++ + G  +  +       +  S  G    T    G  +   S A   +  V+ A   
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA--- 989

Query: 363  VSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQG 422
              S   T+   G++   V+S        G  T  V     E    S   S    T+T  G
Sbjct: 990  -GSETTTASIEGSETTTVSST-------GSETTTVSTTGTETTITSTEGSET-TTVTTAG 1040

Query: 423  NLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSK 482
            +      + V ++GS +   S           S  ++  +  S + T  T    ++ VS 
Sbjct: 1041 S----ETTAVYTTGSETTTTSTE--------GSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 483  DGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSE 542
             G G  + S+  +   ++ I+ S     S   S     S+     T    T S  TT+  
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV-- 1146

Query: 543  SDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPS 602
                            +T  S+  T         + SA G + T  ++  S  ++ ++  
Sbjct: 1147 ----------------FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 603  GTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTM 662
                  S   S TT    + S  T   T S S ++            N++ +   ++ T 
Sbjct: 1191 SETTTASTAGSETTTASTAGSETT---TASTSGSE-----------TNTACTTGSETSTP 1236

Query: 663  SRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQL 722
            S +GS       + GS  + ++ST+S+  T      SE   +   + AS    +A TT  
Sbjct: 1237 SSAGS-ETNTAFIIGSE-TTIASTASLEPTATSLTGSETTTV--SITAS-GATAASTTVS 1291

Query: 723  TANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVI 782
            +    L  A + S+  +T    S T T   + +  + +     +    +AA+      V+
Sbjct: 1292 STTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVL 1351

Query: 783  NTPELNCKGNG---TAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDS 831
            NT  L     G   T  +  +R     + +  SS    T   S+G+N  S S
Sbjct: 1352 NTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMS 1403



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 123/739 (16%), Positives = 258/739 (34%), Gaps = 77/739 (10%)

Query: 173 VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRS 232
           +K S +    ++G E+  P P+ S+T   + +  G +  + S AG    T S        
Sbjct: 30  IKASETTTASTAGSETTTPSPTGSQTTIVSIS--GSEITTTSTAGSENTTVSS---AGSG 84

Query: 233 ATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAG 292
            T   +  S   VS +    +++     +     A+ S T     +    S++   + AG
Sbjct: 85  TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTT---SSETTVTSTAG 141

Query: 293 NRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCN 352
           + ++T S        + G               +S  G    T    G  +   S A   
Sbjct: 142 SETTTVS--------TVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412
           +  V+ A    ++ + T  +        +  T     G + TK   ++TA    +   +S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK---VSTA---GSETTVS 247

Query: 413 NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGT 472
              +  T     DS + +       ++   +   +       ++ S+  S P+ + T G+
Sbjct: 248 TAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE------TTAASTTGSEPTMASTMGS 301

Query: 473 NASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVR 532
             + +S +  +       + + T+   +    ++G      S+ G               
Sbjct: 302 ETTMASTIGPE------TTKVSTASSEVTTVFAAGSETIRASTVG-------------SE 342

Query: 533 TNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPF 592
           T +V TT SE+       T    G      S+  T         + S  G + T A++  
Sbjct: 343 TTTVSTTGSET------TTASIMG------SETSTDSTTGSETTTASTEGSETTTASTEG 390

Query: 593 SSGSSVTSPSGTRFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSNADGQYDPYTDSR 647
           S  ++V++        S   S TT T     +M+  + T+  T + S    +    + S 
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 648 FRNSSMSLD-EKSRTMSRSGS-----FRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEI 701
              ++ S +  ++ T++ +GS     +  G E    S+  L ++T     +      +E 
Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG 510

Query: 702 RKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDS---ELN 758
            +    + A+  +++ ++T+ + N  +     ++    T  L++ T + E  +       
Sbjct: 511 SE-TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569

Query: 759 ELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSAT 818
               T +  +     A +       T       N TA +AD       ++ S ++  S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629

Query: 819 SHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLP 878
           S  +  ++ E             ++     G   S ++ +S    E  T S+  S   + 
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTG---SERTITSTEGSETTTVSATGSETTVS 686

Query: 879 HNGSTGSTPLLRNSHSNSL 897
             GS  +T  +  S +  +
Sbjct: 687 TEGSGTTTVSITGSETTKV 705


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 137/699 (19%), Positives = 257/699 (36%), Gaps = 46/699 (6%)

Query: 14  SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
           ++V+          ST    T++ +   + T  +S    +  T +   SQ    S+   +
Sbjct: 5   TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE 64

Query: 74  DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
               S  GS++      GS      S    E+  ST+G +   +S TG+    ++A    
Sbjct: 65  ITTTSTAGSENTTVSSAGSG-TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 134 TMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGR------SSGDE 187
           T   +  S+      T G+  T  + V  +   +  A     + S  G       ++G E
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE 183

Query: 188 SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV-TVTSRSATLGKIPKSSALVS 246
           +  P  + S T T   ++ G +  + S  G    TAS   + T+ ++T+G    S     
Sbjct: 184 TITPSTAGSETTT--VSTAGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKV 237

Query: 247 RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
            +AG ++++  A ++        S TN  +    + + +++       +ST+  +  ++S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 307 KSAGLPVPKLR---EPSKTALGSSLPGLV----NQTDKEKGISSDNESVASCNSVKVNPA 359
                         E +K +  SS    V    ++T +   + S+  +V++  S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS--ETTT 355

Query: 360 AQPVSSPAQTSLQPGAKYPDVA---SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHA 416
           A  + S   T    G++    +   S T      G     V    +E    S+  S    
Sbjct: 356 ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTT 415

Query: 417 TMTQQGNLDSPSGS---GVLSSGSSSPLYSKNVDLNQSPLASSPSS----AHSAPSNSLT 469
           T T+   + + S +      +S   S +   +   +++  AS+  S      +A S + T
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475

Query: 470 WGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP 529
             T  S ++  S  GL   +V ++ +   +     S     S   S     S++    T 
Sbjct: 476 AYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTT 535

Query: 530 FVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
              T S  TT+S +   L+  T   +G      S++ T         + S  G   TAA+
Sbjct: 536 VSTTGSETTTVSTTG--LETTTTSTEG------SEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 590 SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFR 649
           +  S  ++V++        S   S TT    + S  T   T S           T+    
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS----TEGSET 643

Query: 650 NSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSS 688
            +  + D ++  +S +GS R       GS  + VS+T S
Sbjct: 644 TTVSTTDSETTMVSTTGSERT-ITSTEGSETTTVSATGS 681



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 113/636 (17%), Positives = 227/636 (35%), Gaps = 52/636 (8%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++VS+  S+TI           +S +    T  +S +  +  T + + S+    
Sbjct: 817  TTASETTTVSTAGSETI----------PASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S  S +    +  GS++      GS+     ++ S+ +  ST G +   +S TGS     
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            + +   T   T  S     L T  T  ++   VS +G  +   + +  S +    ++G E
Sbjct: 927  STEGSET---TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM-GSETTTASTAGSE 982

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247
            +     + S T TA+          GS       T S  T  S + T       + + S 
Sbjct: 983  TTTVSTAGSETTTASI--------EGSETTTVSSTGSETTTVSTTGT------ETTITST 1028

Query: 248  SAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID-SNISS 306
                 +++  A ++        S T          +  ++       +ST+ ++ + +S+
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 307  KSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSP 366
              +G           T +   + G    T   +G  +   S  S  +   +     +++ 
Sbjct: 1089 SGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT- 1145

Query: 367  AQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDS 426
              T++        + S        G          +E    S   S      T      +
Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTT 1205

Query: 427  PSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLG 486
             S +G  ++ +S+     N         S+PSSA S  + +   G+  + +S  S +   
Sbjct: 1206 ASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTA 1265

Query: 487  FQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPH 546
              S++   T+  SI  S ++    + +S+T ++  + D S+ P   T    T  + +   
Sbjct: 1266 -TSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLT 1324

Query: 547  LDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGG--LQDTAANSPFSSGSSVTSPSGT 604
               +     G+ +T ++             SH+  G  L  +   +     SS TS  G 
Sbjct: 1325 ASSSVTMAPGMDFTASA------------ASHTVPGIVLNTSGLGTSTMGASSTTSAHGV 1372

Query: 605  RFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSN 635
            R        PT+ T      +S+   T+  +H+ +N
Sbjct: 1373 RTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTN 1408



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 150/814 (18%), Positives = 301/814 (36%), Gaps = 77/814 (9%)

Query: 6   NLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVE 65
           N T+  +++  S+  S+T   +ST    T+++ ++ + T A+S    ++ T     S+  
Sbjct: 127 NSTTSSETTVTSTAGSETT-TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185

Query: 66  RNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR 125
             S    +    S  GS++      GS+     +  S+ +  ST G +   +S  GS   
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 126 GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
             TA    T   T+ S          T  T+D+K +       + +    + S+   +S 
Sbjct: 246 VSTAGSETTAASTEDS-------ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 186 DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALV 245
             S+  + S+    T   ++   +  +  AAG   I AS  TV S + T+      +   
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS--TVGSETTTVSTTGSETTTA 356

Query: 246 SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI-DSNI 304
           S   G ++S D     +      S+  +    +    S++ + +  G+ ++T SI DS  
Sbjct: 357 S-IMGSETSTDSTTGSET--TTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 305 S------SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKE------KGISSDNESVASCN 352
           +      S+   +        + +  GS +  + + +D E      +G  +   + A   
Sbjct: 414 TTTCTEGSEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT------KQVPIATAENMK 406
           +          ++ + T L+    +   +  T     G + T       ++   + E  +
Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 407 NSVVISNPHATMT-------------------------QQGNLDSPSGSGVL---SSGSS 438
           N+ V +    T T                          +   DS  GSG     ++GS 
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 439 SPLYS--KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTS 496
           +   S   + +   S   S  +SA +  S + T  T +S ++  S +G    +VS+  + 
Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 497 CESIDISLSSGGVPS-HNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKK 555
              +  + S   + S   S T  ++++  ++      + +   +++ S+      T  + 
Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSET 712

Query: 556 GLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPT 615
               T  S++ T         + S  G + T A++  S  +S ++        S  +S T
Sbjct: 713 TTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772

Query: 616 TVTQMSLSNPTML-----RTHSLSNADGQYDP-YTDSRFRNSSMSLDEKSRTMSRSGSFR 669
           T+  +  S  TM       T  +S A  +    +T++     + +   ++ T+S +GS  
Sbjct: 773 TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-- 830

Query: 670 DGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLV 729
              E +  S+    S T++  ST   +  +   +      AS E     T     +    
Sbjct: 831 ---ETIPASTAG--SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 730 AAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKT 763
           A+ E S    T    S T TA  + SE+  +  T
Sbjct: 886 ASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 919



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 136/748 (18%), Positives = 273/748 (36%), Gaps = 64/748 (8%)

Query: 4   PRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQ 63
           P   ++    ++++S I      +ST     ++  ++ + T  +S    +  T +   S+
Sbjct: 293 PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSE 352

Query: 64  VERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
               S+   +    S  GS++      GS+     ++ S+ +  ST+G +   +S T S 
Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS- 411

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRS 183
               T   G  M     +A +  +    T  T+ ++++         +    S +    +
Sbjct: 412 ETTTTCTEGSEM-----TAVSTTVFETTTASTEGSEIT--------IASTSDSETTTAST 458

Query: 184 SGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSA 243
            G E+     + S T TA         ++ +A+   + T +  T+ S + T       + 
Sbjct: 459 EGSETTTVTTAGSETKTAYTTG----SETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 244 LVSRSAGRKS--SMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
            VS +    +  S +G++N        S  T +    L   + S   +     S+T +  
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTG-SETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 302 SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
           +  S++ +G           T + ++       ++     ++D+E+ ++  +      A 
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTA------DSENTTASTADSETTSASTTGSETTTAS 627

Query: 362 PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQ 421
             SS   T+   G++   V++             +  I + E  + + V +    T    
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV-- 685

Query: 422 GNLDSPSGSG---VLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASS 476
               S  GSG   V  +GS +   S   +     S   S  ++A    S + T  T  S 
Sbjct: 686 ----STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 477 SSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSV 536
           ++  S +  G ++ S+  T  E+   S +S    S  +   ++ S    + T    T  V
Sbjct: 742 TTTASTE--GSETTSASTTGSETTTASTTS----SETTMASIMGSETTMASTIGSETTKV 795

Query: 537 KTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 596
            T  S+       N+  +  +  T  S+  T   A       S  G + T   S   S +
Sbjct: 796 STASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 597 SVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLD 656
           +  S  G+    +   S  T T  ++ + T     + ++ +G     T +    ++ +  
Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGSET-----TTASTEGSETTTTSTEGSETTTAST 908

Query: 657 EKSR--TMSRSGS-----FRDGFE----EVHGSSLSLVSSTSS--VYSTPEEKCQSEIRK 703
           E S   T+S +GS       +G E       GS L+ VS+T S  +  + E    + +  
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968

Query: 704 LRRELDASQEKVSALTTQLTANAHLVAA 731
           +  E   +    S  TT  TA +    A
Sbjct: 969 MGSETTTASTAGSETTTVSTAGSETTTA 996



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 114/600 (19%), Positives = 220/600 (36%), Gaps = 50/600 (8%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++ +S         ST+   T+++ +  + T  ++    +  T + + S+    
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT 896

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S    +    S  GS+       GS+     ++ S+ +  ST G +   +S TGS    +
Sbjct: 897  STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            +A+   T   T  +       T  T  ++   VS  G  +  AS ++ S +    S+G E
Sbjct: 957  SAEGSET---TTVTTMGSETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVSSTGSE 1012

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAG---LAMITASGVTVT-----SRSATLGKIP 239
            +     S++ T T   ++ G +  + + AG    A+ T    T T     S + T+    
Sbjct: 1013 T--TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              +   S +    +++  + +         S T   Y +  + + +++        ST+S
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 300  IDSNISSKSAGLPVPKLREPSKT---------ALGSSLPGLVNQTDKEKGISSDNESVAS 350
             ++  +S +           S+T         A  SS  G    T   +G  +   S A 
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 351  CNSVKVNPA------AQPVSSPAQTSLQPGAKYP---DVASPTLRRLFGGKPTKQVPIAT 401
              +   + A      A    S   T+   G++        S T      G  T    I  
Sbjct: 1191 SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIG 1250

Query: 402  AENMKNSVVISNPHATMTQQGNLD----SPSGSGVLSSGSSSPLY--SKNVDLNQSPLAS 455
            +E    S     P AT            + SG+   S+  SS  +  +K  D++  P+ +
Sbjct: 1251 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITN 1310

Query: 456  SPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSS 515
            +P S        LT     +SSS     G+ F + ++ HT      I L++ G+ +    
Sbjct: 1311 TPMSGTRTTGTRLT-----ASSSVTMAPGMDFTASAASHT---VPGIVLNTSGLGTSTMG 1362

Query: 516  TGLIASSKDDSLTPFVRTNSVKTTLSESDP-HLDRNTLPKKGLRYTPTSQLRTQEDAKEW 574
                 S+     T         +T  E+ P  +  NT+    + +TPT+ ++     + W
Sbjct: 1363 ASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTV---SMSHTPTNVIKPSGYLQPW 1419



 Score = 54.3 bits (129), Expect = 9e-07
 Identities = 158/832 (18%), Positives = 298/832 (35%), Gaps = 96/832 (11%)

Query: 5    RNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQV 64
            R +TS + S + +   + +   +ST+   T++   + + T   S    +  T + + S++
Sbjct: 663  RTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWR 124
               S+   +    S  GS++      GS+     +  S+ +  ST+  +  + S  GS  
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS-E 781

Query: 125  RGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSS 184
              M + +G     TK S  +  + T  T  ++    S              S +    ++
Sbjct: 782  TTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS-----------TTASETTTVSTA 828

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
            G E+     + S T T  +   G +  + S  G    TAS  +  + +AT      ++A 
Sbjct: 829  GSETIPASTAGSETTTTTSTE-GSETTTASTEGSETTTASTESSETTTATTIGSETTTAS 887

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSN- 303
               S    +S +G++                  +    S+  + +  G+ ++T+S + + 
Sbjct: 888  TEGSETTTTSTEGSETT---------------TASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 304  -ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQP 362
              ++ + G  +  +       +  S  G    T    G  +   S A   +  V+ A   
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA--- 989

Query: 363  VSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQG 422
              S   T+   G++   V+S        G  T  V     E    S   S    T+T  G
Sbjct: 990  -GSETTTASIEGSETTTVSST-------GSETTTVSTTGTETTITSTEGSET-TTVTTAG 1040

Query: 423  NLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSK 482
            +      + V ++GS +   S           S  ++  +  S + T  T    ++ VS 
Sbjct: 1041 S----ETTAVYTTGSETTTTSTE--------GSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 483  DGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSE 542
             G G  + S+  +   ++ I+ S     S   S     S+     T    T S  TT+  
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV-- 1146

Query: 543  SDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPS 602
                            +T  S+  T         + SA G + T  ++  S  ++ ++  
Sbjct: 1147 ----------------FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 603  GTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTM 662
                  S   S TT    + S  T   T S S ++            N++ +   ++ T 
Sbjct: 1191 SETTTASTAGSETTTASTAGSETT---TASTSGSE-----------TNTACTTGSETSTP 1236

Query: 663  SRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQL 722
            S +GS       + GS  + ++ST+S+  T      SE   +   + AS    +A TT  
Sbjct: 1237 SSAGS-ETNTAFIIGSE-TTIASTASLEPTATSLTGSETTTV--SITAS-GATAASTTVS 1291

Query: 723  TANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVI 782
            +    L  A + S+  +T    S T T   + +  + +     +    +AA+      V+
Sbjct: 1292 STTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVL 1351

Query: 783  NTPELNCKGNG---TAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDS 831
            NT  L     G   T  +  +R     + +  SS    T   S+G+N  S S
Sbjct: 1352 NTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMS 1403



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 123/739 (16%), Positives = 258/739 (34%), Gaps = 77/739 (10%)

Query: 173 VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRS 232
           +K S +    ++G E+  P P+ S+T   + +  G +  + S AG    T S        
Sbjct: 30  IKASETTTASTAGSETTTPSPTGSQTTIVSIS--GSEITTTSTAGSENTTVSS---AGSG 84

Query: 233 ATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAG 292
            T   +  S   VS +    +++     +     A+ S T     +    S++   + AG
Sbjct: 85  TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTT---SSETTVTSTAG 141

Query: 293 NRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCN 352
           + ++T S        + G               +S  G    T    G  +   S A   
Sbjct: 142 SETTTVS--------TVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412
           +  V+ A    ++ + T  +        +  T     G + TK   ++TA    +   +S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK---VSTA---GSETTVS 247

Query: 413 NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGT 472
              +  T     DS + +       ++   +   +       ++ S+  S P+ + T G+
Sbjct: 248 TAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE------TTAASTTGSEPTMASTMGS 301

Query: 473 NASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVR 532
             + +S +  +       + + T+   +    ++G      S+ G               
Sbjct: 302 ETTMASTIGPE------TTKVSTASSEVTTVFAAGSETIRASTVG-------------SE 342

Query: 533 TNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPF 592
           T +V TT SE+       T    G      S+  T         + S  G + T A++  
Sbjct: 343 TTTVSTTGSET------TTASIMG------SETSTDSTTGSETTTASTEGSETTTASTEG 390

Query: 593 SSGSSVTSPSGTRFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSNADGQYDPYTDSR 647
           S  ++V++        S   S TT T     +M+  + T+  T + S    +    + S 
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 648 FRNSSMSLD-EKSRTMSRSGS-----FRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEI 701
              ++ S +  ++ T++ +GS     +  G E    S+  L ++T     +      +E 
Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG 510

Query: 702 RKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDS---ELN 758
            +    + A+  +++ ++T+ + N  +     ++    T  L++ T + E  +       
Sbjct: 511 SE-TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569

Query: 759 ELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSAT 818
               T +  +     A +       T       N TA +AD       ++ S ++  S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629

Query: 819 SHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLP 878
           S  +  ++ E             ++     G   S ++ +S    E  T S+  S   + 
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTG---SERTITSTEGSETTTVSATGSETTVS 686

Query: 879 HNGSTGSTPLLRNSHSNSL 897
             GS  +T  +  S +  +
Sbjct: 687 TEGSGTTTVSITGSETTKV 705


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 137/699 (19%), Positives = 257/699 (36%), Gaps = 46/699 (6%)

Query: 14  SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
           ++V+          ST    T++ +   + T  +S    +  T +   SQ    S+   +
Sbjct: 5   TTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSE 64

Query: 74  DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
               S  GS++      GS      S    E+  ST+G +   +S TG+    ++A    
Sbjct: 65  ITTTSTAGSENTTVSSAGSG-TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE 123

Query: 134 TMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGR------SSGDE 187
           T   +  S+      T G+  T  + V  +   +  A     + S  G       ++G E
Sbjct: 124 TTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE 183

Query: 188 SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV-TVTSRSATLGKIPKSSALVS 246
           +  P  + S T T   ++ G +  + S  G    TAS   + T+ ++T+G    S     
Sbjct: 184 TITPSTAGSETTT--VSTAGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKV 237

Query: 247 RSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISS 306
            +AG ++++  A ++        S TN  +    + + +++       +ST+  +  ++S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 307 KSAGLPVPKLR---EPSKTALGSSLPGLV----NQTDKEKGISSDNESVASCNSVKVNPA 359
                         E +K +  SS    V    ++T +   + S+  +V++  S      
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGS--ETTT 355

Query: 360 AQPVSSPAQTSLQPGAKYPDVA---SPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHA 416
           A  + S   T    G++    +   S T      G     V    +E    S+  S    
Sbjct: 356 ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTT 415

Query: 417 TMTQQGNLDSPSGS---GVLSSGSSSPLYSKNVDLNQSPLASSPSS----AHSAPSNSLT 469
           T T+   + + S +      +S   S +   +   +++  AS+  S      +A S + T
Sbjct: 416 TCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475

Query: 470 WGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP 529
             T  S ++  S  GL   +V ++ +   +     S     S   S     S++    T 
Sbjct: 476 AYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTT 535

Query: 530 FVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
              T S  TT+S +   L+  T   +G      S++ T         + S  G   TAA+
Sbjct: 536 VSTTGSETTTVSTTG--LETTTTSTEG------SEMTTVSTTGAETTTDSTEGSGTTAAS 587

Query: 590 SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFR 649
           +  S  ++V++        S   S TT    + S  T   T S           T+    
Sbjct: 588 TAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS----TEGSET 643

Query: 650 NSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSS 688
            +  + D ++  +S +GS R       GS  + VS+T S
Sbjct: 644 TTVSTTDSETTMVSTTGSERT-ITSTEGSETTTVSATGS 681



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 113/636 (17%), Positives = 227/636 (35%), Gaps = 52/636 (8%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++VS+  S+TI           +S +    T  +S +  +  T + + S+    
Sbjct: 817  TTASETTTVSTAGSETI----------PASTAGSETTTTTSTEGSETTTASTEGSETTTA 866

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S  S +    +  GS++      GS+     ++ S+ +  ST G +   +S TGS     
Sbjct: 867  STESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            + +   T   T  S     L T  T  ++   VS +G  +   + +  S +    ++G E
Sbjct: 927  STEGSET---TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM-GSETTTASTAGSE 982

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSR 247
            +     + S T TA+          GS       T S  T  S + T       + + S 
Sbjct: 983  TTTVSTAGSETTTASI--------EGSETTTVSSTGSETTTVSTTGT------ETTITST 1028

Query: 248  SAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID-SNISS 306
                 +++  A ++        S T          +  ++       +ST+ ++ + +S+
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 307  KSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSP 366
              +G           T +   + G    T   +G  +   S  S  +   +     +++ 
Sbjct: 1089 SGSGTTTASTAGSETTTV--YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT- 1145

Query: 367  AQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDS 426
              T++        + S        G          +E    S   S      T      +
Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTT 1205

Query: 427  PSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLG 486
             S +G  ++ +S+     N         S+PSSA S  + +   G+  + +S  S +   
Sbjct: 1206 ASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTA 1265

Query: 487  FQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPH 546
              S++   T+  SI  S ++    + +S+T ++  + D S+ P   T    T  + +   
Sbjct: 1266 -TSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLT 1324

Query: 547  LDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGG--LQDTAANSPFSSGSSVTSPSGT 604
               +     G+ +T ++             SH+  G  L  +   +     SS TS  G 
Sbjct: 1325 ASSSVTMAPGMDFTASA------------ASHTVPGIVLNTSGLGTSTMGASSTTSAHGV 1372

Query: 605  RFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSN 635
            R        PT+ T      +S+   T+  +H+ +N
Sbjct: 1373 RTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTN 1408



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 150/814 (18%), Positives = 301/814 (36%), Gaps = 77/814 (9%)

Query: 6   NLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVE 65
           N T+  +++  S+  S+T   +ST    T+++ ++ + T A+S    ++ T     S+  
Sbjct: 127 NSTTSSETTVTSTAGSETT-TVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETI 185

Query: 66  RNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR 125
             S    +    S  GS++      GS+     +  S+ +  ST G +   +S  GS   
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245

Query: 126 GMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSG 185
             TA    T   T+ S          T  T+D+K +       + +    + S+   +S 
Sbjct: 246 VSTAGSETTAASTEDS-------ETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 186 DESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALV 245
             S+  + S+    T   ++   +  +  AAG   I AS  TV S + T+      +   
Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS--TVGSETTTVSTTGSETTTA 356

Query: 246 SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI-DSNI 304
           S   G ++S D     +      S+  +    +    S++ + +  G+ ++T SI DS  
Sbjct: 357 S-IMGSETSTDSTTGSET--TTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413

Query: 305 S------SKSAGLPVPKLREPSKTALGSSLPGLVNQTDKE------KGISSDNESVASCN 352
           +      S+   +        + +  GS +  + + +D E      +G  +   + A   
Sbjct: 414 TTTCTEGSEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGSE 472

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPT------KQVPIATAENMK 406
           +          ++ + T L+    +   +  T     G + T       ++   + E  +
Sbjct: 473 TKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSE 532

Query: 407 NSVVISNPHATMT-------------------------QQGNLDSPSGSGVL---SSGSS 438
           N+ V +    T T                          +   DS  GSG     ++GS 
Sbjct: 533 NTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 439 SPLYS--KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTS 496
           +   S   + +   S   S  +SA +  S + T  T +S ++  S +G    +VS+  + 
Sbjct: 593 TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSE 652

Query: 497 CESIDISLSSGGVPS-HNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKK 555
              +  + S   + S   S T  ++++  ++      + +   +++ S+      T  + 
Sbjct: 653 TTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSET 712

Query: 556 GLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPT 615
               T  S++ T         + S  G + T A++  S  +S ++        S  +S T
Sbjct: 713 TTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET 772

Query: 616 TVTQMSLSNPTML-----RTHSLSNADGQYDP-YTDSRFRNSSMSLDEKSRTMSRSGSFR 669
           T+  +  S  TM       T  +S A  +    +T++     + +   ++ T+S +GS  
Sbjct: 773 TMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-- 830

Query: 670 DGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLV 729
              E +  S+    S T++  ST   +  +   +      AS E     T     +    
Sbjct: 831 ---ETIPASTAG--SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 730 AAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKT 763
           A+ E S    T    S T TA  + SE+  +  T
Sbjct: 886 ASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 919



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 136/748 (18%), Positives = 273/748 (36%), Gaps = 64/748 (8%)

Query: 4   PRNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQ 63
           P   ++    ++++S I      +ST     ++  ++ + T  +S    +  T +   S+
Sbjct: 293 PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSE 352

Query: 64  VERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
               S+   +    S  GS++      GS+     ++ S+ +  ST+G +   +S T S 
Sbjct: 353 TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS- 411

Query: 124 RRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRS 183
               T   G  M     +A +  +    T  T+ ++++         +    S +    +
Sbjct: 412 ETTTTCTEGSEM-----TAVSTTVFETTTASTEGSEIT--------IASTSDSETTTAST 458

Query: 184 SGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSA 243
            G E+     + S T TA         ++ +A+   + T +  T+ S + T       + 
Sbjct: 459 EGSETTTVTTAGSETKTAYTTG----SETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514

Query: 244 LVSRSAGRKS--SMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
            VS +    +  S +G++N        S  T +    L   + S   +     S+T +  
Sbjct: 515 AVSATGSEMTTVSTEGSENTTVSTTG-SETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 302 SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
           +  S++ +G           T + ++       ++     ++D+E+ ++  +      A 
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTA------DSENTTASTADSETTSASTTGSETTTAS 627

Query: 362 PVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQ 421
             SS   T+   G++   V++             +  I + E  + + V +    T    
Sbjct: 628 TTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV-- 685

Query: 422 GNLDSPSGSG---VLSSGSSSPLYSK--NVDLNQSPLASSPSSAHSAPSNSLTWGTNASS 476
               S  GSG   V  +GS +   S   +     S   S  ++A    S + T  T  S 
Sbjct: 686 ----STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 477 SSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSV 536
           ++  S +  G ++ S+  T  E+   S +S    S  +   ++ S    + T    T  V
Sbjct: 742 TTTASTE--GSETTSASTTGSETTTASTTS----SETTMASIMGSETTMASTIGSETTKV 795

Query: 537 KTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGS 596
            T  S+       N+  +  +  T  S+  T   A       S  G + T   S   S +
Sbjct: 796 STASSKMTTVFTENS--ETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 597 SVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLD 656
           +  S  G+    +   S  T T  ++ + T     + ++ +G     T +    ++ +  
Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGSET-----TTASTEGSETTTTSTEGSETTTAST 908

Query: 657 EKSR--TMSRSGS-----FRDGFE----EVHGSSLSLVSSTSS--VYSTPEEKCQSEIRK 703
           E S   T+S +GS       +G E       GS L+ VS+T S  +  + E    + +  
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968

Query: 704 LRRELDASQEKVSALTTQLTANAHLVAA 731
           +  E   +    S  TT  TA +    A
Sbjct: 969 MGSETTTASTAGSETTTVSTAGSETTTA 996



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 114/600 (19%), Positives = 220/600 (36%), Gaps = 50/600 (8%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERN 67
            T+  ++++ +S         ST+   T+++ +  + T  ++    +  T + + S+    
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT 896

Query: 68   SLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGM 127
            S    +    S  GS+       GS+     ++ S+ +  ST G +   +S TGS    +
Sbjct: 897  STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 128  TAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
            +A+   T   T  +       T  T  ++   VS  G  +  AS ++ S +    S+G E
Sbjct: 957  SAEGSET---TTVTTMGSETTTASTAGSETTTVSTAGSETTTAS-IEGSETTTVSSTGSE 1012

Query: 188  SKKPLPSSSRTPTANANSFGFKKQSGSAAG---LAMITASGVTVT-----SRSATLGKIP 239
            +     S++ T T   ++ G +  + + AG    A+ T    T T     S + T+    
Sbjct: 1013 T--TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              +   S +    +++  + +         S T   Y +  + + +++        ST+S
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 300  IDSNISSKSAGLPVPKLREPSKT---------ALGSSLPGLVNQTDKEKGISSDNESVAS 350
             ++  +S +           S+T         A  SS  G    T   +G  +   S A 
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 351  CNSVKVNPA------AQPVSSPAQTSLQPGAKYP---DVASPTLRRLFGGKPTKQVPIAT 401
              +   + A      A    S   T+   G++        S T      G  T    I  
Sbjct: 1191 SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIG 1250

Query: 402  AENMKNSVVISNPHATMTQQGNLD----SPSGSGVLSSGSSSPLY--SKNVDLNQSPLAS 455
            +E    S     P AT            + SG+   S+  SS  +  +K  D++  P+ +
Sbjct: 1251 SETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITN 1310

Query: 456  SPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSS 515
            +P S        LT     +SSS     G+ F + ++ HT      I L++ G+ +    
Sbjct: 1311 TPMSGTRTTGTRLT-----ASSSVTMAPGMDFTASAASHT---VPGIVLNTSGLGTSTMG 1362

Query: 516  TGLIASSKDDSLTPFVRTNSVKTTLSESDP-HLDRNTLPKKGLRYTPTSQLRTQEDAKEW 574
                 S+     T         +T  E+ P  +  NT+    + +TPT+ ++     + W
Sbjct: 1363 ASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTV---SMSHTPTNVIKPSGYLQPW 1419



 Score = 54.3 bits (129), Expect = 9e-07
 Identities = 158/832 (18%), Positives = 298/832 (35%), Gaps = 96/832 (11%)

Query: 5    RNLTSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQV 64
            R +TS + S + +   + +   +ST+   T++   + + T   S    +  T + + S++
Sbjct: 663  RTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWR 124
               S+   +    S  GS++      GS+     +  S+ +  ST+  +  + S  GS  
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS-E 781

Query: 125  RGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSS 184
              M + +G     TK S  +  + T  T  ++    S              S +    ++
Sbjct: 782  TTMASTIG--SETTKVSTASSKMTTVFTENSETTIAS-----------TTASETTTVSTA 828

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
            G E+     + S T T  +   G +  + S  G    TAS  +  + +AT      ++A 
Sbjct: 829  GSETIPASTAGSETTTTTSTE-GSETTTASTEGSETTTASTESSETTTATTIGSETTTAS 887

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSN- 303
               S    +S +G++                  +    S+  + +  G+ ++T+S + + 
Sbjct: 888  TEGSETTTTSTEGSETT---------------TASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 304  -ISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQP 362
              ++ + G  +  +       +  S  G    T    G  +   S A   +  V+ A   
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA--- 989

Query: 363  VSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQG 422
              S   T+   G++   V+S        G  T  V     E    S   S    T+T  G
Sbjct: 990  -GSETTTASIEGSETTTVSST-------GSETTTVSTTGTETTITSTEGSET-TTVTTAG 1040

Query: 423  NLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSK 482
            +      + V ++GS +   S           S  ++  +  S + T  T    ++ VS 
Sbjct: 1041 S----ETTAVYTTGSETTTTSTE--------GSETTTVSTTGSETTTASTADLETTTVST 1088

Query: 483  DGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSE 542
             G G  + S+  +   ++ I+ S     S   S     S+     T    T S  TT+  
Sbjct: 1089 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTV-- 1146

Query: 543  SDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPS 602
                            +T  S+  T         + SA G + T  ++  S  ++ ++  
Sbjct: 1147 ----------------FTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAG 1190

Query: 603  GTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTM 662
                  S   S TT    + S  T   T S S ++            N++ +   ++ T 
Sbjct: 1191 SETTTASTAGSETTTASTAGSETT---TASTSGSE-----------TNTACTTGSETSTP 1236

Query: 663  SRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQL 722
            S +GS       + GS  + ++ST+S+  T      SE   +   + AS    +A TT  
Sbjct: 1237 SSAGS-ETNTAFIIGSE-TTIASTASLEPTATSLTGSETTTV--SITAS-GATAASTTVS 1291

Query: 723  TANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVI 782
            +    L  A + S+  +T    S T T   + +  + +     +    +AA+      V+
Sbjct: 1292 STTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVL 1351

Query: 783  NTPELNCKGNG---TAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDS 831
            NT  L     G   T  +  +R     + +  SS    T   S+G+N  S S
Sbjct: 1352 NTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMS 1403



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 123/739 (16%), Positives = 258/739 (34%), Gaps = 77/739 (10%)

Query: 173 VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRS 232
           +K S +    ++G E+  P P+ S+T   + +  G +  + S AG    T S        
Sbjct: 30  IKASETTTASTAGSETTTPSPTGSQTTIVSIS--GSEITTTSTAGSENTTVSS---AGSG 84

Query: 233 ATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAG 292
            T   +  S   VS +    +++     +     A+ S T     +    S++   + AG
Sbjct: 85  TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTT---SSETTVTSTAG 141

Query: 293 NRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCN 352
           + ++T S        + G               +S  G    T    G  +   S A   
Sbjct: 142 SETTTVS--------TVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSE 193

Query: 353 SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412
           +  V+ A    ++ + T  +        +  T     G + TK   ++TA    +   +S
Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTK---VSTA---GSETTVS 247

Query: 413 NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGT 472
              +  T     DS + +       ++   +   +       ++ S+  S P+ + T G+
Sbjct: 248 TAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE------TTAASTTGSEPTMASTMGS 301

Query: 473 NASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVR 532
             + +S +  +       + + T+   +    ++G      S+ G               
Sbjct: 302 ETTMASTIGPE------TTKVSTASSEVTTVFAAGSETIRASTVG-------------SE 342

Query: 533 TNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPF 592
           T +V TT SE+       T    G      S+  T         + S  G + T A++  
Sbjct: 343 TTTVSTTGSET------TTASIMG------SETSTDSTTGSETTTASTEGSETTTASTEG 390

Query: 593 SSGSSVTSPSGTRFNFSQLASPTTVT-----QMSLSNPTMLRTHSLSNADGQYDPYTDSR 647
           S  ++V++        S   S TT T     +M+  + T+  T + S    +    + S 
Sbjct: 391 SEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 648 FRNSSMSLD-EKSRTMSRSGS-----FRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEI 701
              ++ S +  ++ T++ +GS     +  G E    S+  L ++T     +      +E 
Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEG 510

Query: 702 RKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDS---ELN 758
            +    + A+  +++ ++T+ + N  +     ++    T  L++ T + E  +       
Sbjct: 511 SE-TTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT 569

Query: 759 ELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSAT 818
               T +  +     A +       T       N TA +AD       ++ S ++  S T
Sbjct: 570 GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTT 629

Query: 819 SHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLP 878
           S  +  ++ E             ++     G   S ++ +S    E  T S+  S   + 
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTG---SERTITSTEGSETTTVSATGSETTVS 686

Query: 879 HNGSTGSTPLLRNSHSNSL 897
             GS  +T  +  S +  +
Sbjct: 687 TEGSGTTTVSITGSETTKV 705


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 160/720 (22%), Positives = 273/720 (37%), Gaps = 74/720 (10%)

Query: 12   DSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQ---TDAEKHSQVERNS 68
            D+SS S+G +  +   +T  ++T  +   +  +P+S+          TDA   S     S
Sbjct: 2629 DTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATS 2688

Query: 69   LWSGDDVKKSDGGSDSGIKMEPGS--KWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRG 126
            L   D      G + S     P S       P  V+D S  ST    +  ++   S   G
Sbjct: 2689 LPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTG 2748

Query: 127  MTAQVGITMPRTKPSA-----PAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAG 181
                + +T   +  +      P  +L +  TG T    V++    S   +      S + 
Sbjct: 2749 HATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSS 2808

Query: 182  RSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKS 241
             S+GD +  P+  +S   T +A S      S ++ G A       T ++ +     +P +
Sbjct: 2809 VSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVT 2868

Query: 242  SALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
                S S G  +S+      D   ++    T L   S   PS +++    G+ +     D
Sbjct: 2869 DT-SSASIGHATSLPVT---DTSSISTGHATPLHVTS---PSSAST----GHATPLPVTD 2917

Query: 302  SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
            ++ +S     P+  +  PS  + G + P  V  T       +    V S +SV       
Sbjct: 2918 TSSASTGHANPL-HVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTP 2976

Query: 362  -PVSSPAQTSLQPGAKYP--DVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATM 418
             PV+SP+  S       P  D +S +  +      T     +T +     + +++  +  
Sbjct: 2977 LPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDT--TPLPVTDTSSAS 3034

Query: 419  TQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSS 478
            T Q      +    +S+G ++PL             +SPSSA +  +  L   T+ASS+S
Sbjct: 3035 TGQATPLPVTSLSSVSTGDTTPL-----------PVTSPSSASTGHATPLL-VTDASSAS 3082

Query: 479  AVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGL------IASSKDDSLTPFVR 532
                  L   S+SS+ T  ++  + ++S    S   +T L       AS+ D +  P   
Sbjct: 3083 TGQATPLPVTSLSSVSTG-DTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTD 3141

Query: 533  TNSVKTTLSESDPHLD---RNTLPKKGLRYTPTSQLRTQEDAKEWL---RSHSAGGLQDT 586
            T+S  T  + S P  D    +T     L  T TS + T       +    S S G     
Sbjct: 3142 TSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPL 3201

Query: 587  AANSPFSSGSSVTSP---SGTRFNFSQLASPTTVTQM---SLSNPTMLRTHSLSNAD-GQ 639
               SP S+ +  T+P   + T    +  A+P  VT +   S  + T L    +S+A  GQ
Sbjct: 3202 HVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQ 3261

Query: 640  YDPY----TDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSL--VSSTSSVYSTP 693
              P     T S     +M L   S + + +G         H + L +   SS S+ ++TP
Sbjct: 3262 ATPLPVTNTSSVSTGDTMPLPVTSPSSASTG---------HATPLPVTSTSSASTGHATP 3312



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 103/462 (22%), Positives = 179/462 (38%), Gaps = 50/462 (10%)

Query: 108  STSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLS 167
            STS +++P +SQ G  +   T Q   T     P      + TPG+  T  A       + 
Sbjct: 625  STSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFT--ASGHSPSEIV 682

Query: 168  PK-ASQVKRSPSDAGRSSGD--ESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITAS 224
            P+ A  +  + + A   +GD   ++ P  +    P+++  + G    +  +   A+  A+
Sbjct: 683  PQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLAN 742

Query: 225  GVTVTS-------RSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYR 277
             V  T         SA+    P ++A ++ +   +S+    Q Q     +  SRT     
Sbjct: 743  SVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGT 802

Query: 278  SLPRPSKSNSRNGAGNR-----------SSTSSIDSNISSKSAGLPVPKLRE---PSKTA 323
            + P  S ++    +G+            SS  S DS+ +  +  L          P  T 
Sbjct: 803  ATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTG 862

Query: 324  LGSSL-PGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVAS 382
            + SS+ PG  + T  E   +      +S  S        P +SP +T     A    +A 
Sbjct: 863  MASSIVPGTFHPTLSEASTAGRPTGQSSPTS--------PSASPQET-----AAISRMAQ 909

Query: 383  PTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLY 442
                R   G  T  + +A+      S V   P  ++T  G     + +  LS   S   +
Sbjct: 910  TQRTRTSRGSDT--ISLASQATDTFSTVPPTP-PSITSTGLTSPQTETHTLSPSGSGKTF 966

Query: 443  SKNVDLNQSPL----ASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCE 498
            +  +  N +PL    ASS S+ H+ P + +T  ++ S+  A         SVS+ HT+  
Sbjct: 967  TTALISNATPLPVTYASSASTGHTTPLH-VTDASSVSTGHATPLPVTSPSSVSTGHTTPL 1025

Query: 499  SI--DISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKT 538
             +    S S+G V     ++   AS+ D +  P   T+S  T
Sbjct: 1026 PVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSAST 1067



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 153/718 (21%), Positives = 266/718 (37%), Gaps = 98/718 (13%)

Query: 12   DSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWS 71
            D+SSVS+G +  +   ST   +T      +  +P+S+         A        +S  +
Sbjct: 1269 DTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTG-----HATPLPVTSLSSAST 1323

Query: 72   GDDV-------KKSDGGSDSGIKMEPGSK---WRRNPSDVSDESDKSTSGKKNPV-ISQT 120
            GD +         +  G  + + +   S        P  V+D S  ST G+  P+ ++  
Sbjct: 1324 GDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSAST-GQATPLPVTSL 1382

Query: 121  GSWRRGMTAQVGITMPRTKPSAPAGAL-----KTPGTGKTDDAKVSEKGRLSPKASQVKR 175
             S   G T  + +T P +  +  A  L      +  TG      V++   +S   +    
Sbjct: 1383 SSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLP 1442

Query: 176  SPSDAGRSSGDESKKPLPSSSRTPTANANSF--------------GFKKQSGSAAGLAMI 221
                +  S+G  +  P+  +S   T  A S                    S S+A    +
Sbjct: 1443 VTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHV 1502

Query: 222  TASGVTVTSRSATLGKIP-KSSALVSRSAGRK-----SSMDGAQNQDDGYLALSSRTNLQ 275
            T   VT  S ++T    P   ++L S S G       +S   A   D   L ++  +++ 
Sbjct: 1503 TPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVS 1562

Query: 276  Y-RSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQ 334
               + P P  S S    G+ +     D++ +SK    P+P +  PS  + G + P  +  
Sbjct: 1563 TGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLP-VTSPSSASTGHTTP--LPV 1619

Query: 335  TDKEKGISSDNESVASCNSVKVNPA-AQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGK- 392
            TD     + D   +   N+  ++   A P+   + +S   G   P   + T     G   
Sbjct: 1620 TDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHAT 1679

Query: 393  --PTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQ 450
              P   +  AT ++     V     A+  Q   L   S S V S+G ++PL   +     
Sbjct: 1680 PLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSV-STGDTTPLPVTS----- 1733

Query: 451  SPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVP 510
                SS S+ H++P   +T  ++AS+  A         SVS+ H +   +          
Sbjct: 1734 ---PSSASTGHASPL-LVTDASSASTGQATPLPVTDTSSVSTAHATPLPV---------- 1779

Query: 511  SHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQED 570
                 TGL ++S DD+ T    T+    +  ++ P           L  T  S   T + 
Sbjct: 1780 -----TGLSSASTDDT-TRLPVTDVSSASTGQAIP-----------LPVTSPSSASTGDT 1822

Query: 571  AKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRT 630
                +   S+    DT  + P +  SS +S   T    +  +S +T    SL    +   
Sbjct: 1823 TPLPVTDASSASTGDT-TSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSL---LVTDA 1878

Query: 631  HSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSS 688
             S+S  D    P TD+   NS+ + D     ++ + S   G    H +SL + S +S+
Sbjct: 1879 SSVSTGDTTPLPVTDT---NSASTGDTTPLHVTDASSVSTG----HATSLPVTSLSSA 1929



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 153/669 (22%), Positives = 240/669 (35%), Gaps = 94/669 (14%)

Query: 14   SSVSSGISDTIDNLSTDDINTSSS-------ISSYANTPASSRKNLDVQTDAEKHSQVER 66
            + +SS  +D    L   D++++S+       ++S ++        L V TDA   S  + 
Sbjct: 1780 TGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPV-TDASSASTGDT 1838

Query: 67   NSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSD--VSDESDKSTSGKKNPVISQTGSWR 124
             SL        S G + S    +  S    + +   V+D S  ST       ++ T S  
Sbjct: 1839 TSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSAS 1898

Query: 125  RGMTAQVGITMPRT-----KPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSD 179
             G T  + +T   +       S P  +L +  TG T    V+              SPS 
Sbjct: 1899 TGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVT--------------SPSS 1944

Query: 180  AGRSSGDESKKPLPSSSRTPTANANSFGFKKQS----GSAAGLAMITASGVTVTSRSATL 235
            A  SSG  +  P+  +S  PT +A S      S    G A  L +  AS V+ T  +  L
Sbjct: 1945 A--SSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVS-TGHATPL 2001

Query: 236  GKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRS 295
                 SS     S G+ + +           +LSS +      LP    S++  G     
Sbjct: 2002 PVTDTSSV----STGQATPLP--------VTSLSSASTGDTTPLPVTDTSSASTGQDTPL 2049

Query: 296  STSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVK 355
              +S+ S  +  +  LPV     PS  + G + P LV          + +  V   +SV 
Sbjct: 2050 PVTSLSSVSTGDTTPLPV---TSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVS 2106

Query: 356  VNPAAQPVSSPAQTSLQPGAKYP-DVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNP 414
               A     + A +SL  G   P  V SP+         T  +P+    ++      S P
Sbjct: 2107 TGHATALHVTDA-SSLSTGDTTPLPVTSPSSA---STGDTTPLPVTDTSSVSTGHATSLP 2162

Query: 415  HATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLAS----------SPSSAHSAP 464
              T T   +    +   V  + S+S  ++  + +  +  AS          SPSSA +  
Sbjct: 2163 -VTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGH 2221

Query: 465  SNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCES----IDISLSSGGVPSHNSSTGLIA 520
            +  L   T+ SS+S      L   S+SS  T   +     D S  S G  +    T L +
Sbjct: 2222 AIPLL-VTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSS 2280

Query: 521  SSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSA 580
             S  D+ TP   T+    +   + P           L  T  S   T       + S S+
Sbjct: 2281 VSTGDT-TPLPVTSPSSASTGHATP-----------LHVTDASSASTGHATPLPVTSLSS 2328

Query: 581  GGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQY 640
                DT       +   VTSPS      +     T  + +S  + T L   S S+A   +
Sbjct: 2329 ASTGDT-------TPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGH 2381

Query: 641  D---PYTDS 646
                P TD+
Sbjct: 2382 TTPLPVTDA 2390



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 143/642 (22%), Positives = 230/642 (35%), Gaps = 98/642 (15%)

Query: 12   DSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQT-DAEKHSQVERNSLW 70
            D+SSVS+G +  +       +  +SS+S+   TP        V T  A        +S  
Sbjct: 1973 DASSVSTGHATPLP------VTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSAS 2026

Query: 71   SGD-------DVKKSDGGSDSGI---KMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQT 120
            +GD       D   +  G D+ +    +   S     P  V+  S  ST      +++  
Sbjct: 2027 TGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDA 2086

Query: 121  GSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDA 180
             S   G    + +T   +  +  A AL         DA     G  +P       SPS A
Sbjct: 2087 SSVSTGHATSLLVTDASSVSTGHATALHVT------DASSLSTGDTTPLPVT---SPSSA 2137

Query: 181  GRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPK 240
              S+GD +  P+  +S   T +A S      S ++ G A  T+  VT TS          
Sbjct: 2138 --STGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHA--TSLPVTDTS---------- 2183

Query: 241  SSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSI 300
                 S S G  + +             SS +  Q   LP  S S++  G       +  
Sbjct: 2184 -----SASTGHATPLPVTDT--------SSASTGQATPLPVTSPSSASTGHAIPLLVTDT 2230

Query: 301  DSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAA 360
             S  + ++  LPV  L   S  + G + P  V          + +  V S +SV      
Sbjct: 2231 SSASTGQATPLPVTSL---SSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTT 2287

Query: 361  Q-PVSSP--AQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHAT 417
              PV+SP  A T         D +S +         T     +T +     + +++P + 
Sbjct: 2288 PLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDT--TPLPVTSPSSA 2345

Query: 418  MTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSS 477
             T        + +  +S+G ++PL   +        +SS SS H+ P       T+ASS+
Sbjct: 2346 STGHATPLHVTDASSVSTGDTTPLPVTS--------SSSASSGHTTPLPV----TDASSA 2393

Query: 478  SAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGL-IASSKDDSLTPFVRTNSV 536
            S                T     D S +S G  +H   TGL  AS+ D +  P    +S 
Sbjct: 2394 STGDT------------TPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSA 2441

Query: 537  KT------TLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANS 590
             T       ++ +      +T P  G   T TS + T       +   S+    DT    
Sbjct: 2442 STGHATPLPVTSTSSASTGDTTPLPG---TDTSSVSTGHTTPLLVTDASSVSTGDT-TRL 2497

Query: 591  PFSSGSSVTSPSGTRFNFSQLASPTT--VTQMSLSNPTMLRT 630
            P +S SS ++   T    +   S +T   T + ++N + L T
Sbjct: 2498 PVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLST 2539



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 135/644 (20%), Positives = 228/644 (35%), Gaps = 91/644 (14%)

Query: 12   DSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWS 71
            D+SSVS+G +  +       + + SS+S+   TP          TDA   S  +   L  
Sbjct: 3397 DTSSVSTGHATPLP------VTSLSSVSTGDTTPLPV-------TDASSASTGQATPLPV 3443

Query: 72   GDDVKKSDGGSDSGIKMEPGS--KWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTA 129
                  S G +   +  +  S       P  V+D S  ST       ++ T S   G   
Sbjct: 3444 TSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQAT 3503

Query: 130  QVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESK 189
             + +T           +L +  TG T    V++   +S   +        +  S+GD ++
Sbjct: 3504 PLPVT-----------SLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTR 3552

Query: 190  KPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSA 249
             P+  +S   T  A        S S++G    T   VT TS S + G +         SA
Sbjct: 3553 LPVTDTSSASTGQATPLPVTIPSSSSSG--HTTPLPVTSTS-SVSTGHVTPLHVTSPSSA 3609

Query: 250  GRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSA 309
                          G++             P P  S S    G+ +     D++  S   
Sbjct: 3610 ------------STGHVT------------PLPVTSTSSASTGHATPLLVTDASSVSTGH 3645

Query: 310  GLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ-PVSSPAQ 368
              P+P + + S  + G + P  V  T       +    V S +SV        PV+  + 
Sbjct: 3646 ATPLP-VTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASS 3704

Query: 369  TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPS 428
             S       P V  P+              ++T + M   + +++P +  T        +
Sbjct: 3705 ASTGHATPLP-VTIPS-------------SVSTGDTM--PLPVTSPSSASTGHATPLPVT 3748

Query: 429  GSGVLSSGSSSPL----YSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDG 484
            G    S+G ++PL     S     + +PL  + +S+ S    +    T+ SS+S      
Sbjct: 3749 GLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATP 3808

Query: 485  LGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESD 544
            L   S SS  T  ++  + ++     S   +T L  +S+  + T       V  T S S 
Sbjct: 3809 LPVTSTSSASTG-DTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVST 3867

Query: 545  PHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGT 604
             H          L  T TS + T       + S S+      A   P +S SS ++   T
Sbjct: 3868 GH-------ATPLPVTSTSSVSTGHATPLPVTSPSSAS-TGHATPVPVTSTSSASTGDTT 3919

Query: 605  RFNFSQLASPTT--VTQMSLSNPTMLRTHSLSNADGQYDPYTDS 646
                +  +S +T   T + +++P+     S S  D    P TD+
Sbjct: 3920 PLPVTNASSLSTGHATPLHVTSPS-----SASRGDTSTLPVTDA 3958



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 118/547 (21%), Positives = 191/547 (34%), Gaps = 57/547 (10%)

Query: 117 ISQTGSWRRGMTAQVGITMPRTK-PSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKR 175
           + +T +W    +++   T  +T+ PS   GA     TG           R+  K S +  
Sbjct: 482 LHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGE 541

Query: 176 SPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATL 235
                    G+ +     S++   T  A +     Q     G A++++   +VT    T 
Sbjct: 542 P--------GEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTA 593

Query: 236 GKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRS 295
              P SS ++ R   ++ +   + N    +   +S         P+ S + S+ G     
Sbjct: 594 TS-PSSSPMLDRHTSQQITTAPSTNHSTIHSTSTS---------PQESPAVSQRGHTQAP 643

Query: 296 STSSIDSNISSKSAGLPVPKLREP--SKTALGSSLPGLVNQTDKEKGISSDNESVASCNS 353
            T+       S S       +  P  S TA G S   +V Q         D  ++++  +
Sbjct: 644 QTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQ---------DAPTISAATT 694

Query: 354 VKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS- 412
               P     ++ A T+    A  P     TL    G   +K   +  A    NSVV + 
Sbjct: 695 FAPAPTGDGHTTQAPTTALQAA--PSSHDATLGPSGGTSLSKTGALTLA----NSVVSTP 748

Query: 413 -NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSA----PSNS 467
             P    T      SP  +  ++    +     +     S  ASS S   SA    PS+S
Sbjct: 749 GGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSS 808

Query: 468 LTWGTNASSSSAVSKDG--LGFQSVSSL--HTS---CESIDISLSSGGVPSHNSSTGLIA 520
              GT  S S  +S  G    F S  S   HT+    E +  S S G +P    STG+ +
Sbjct: 809 GASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPV---STGMAS 865

Query: 521 SSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGL---RYTPTSQLRTQEDAKEW-LR 576
           S    +  P +   S     +        +  P++     R   T + RT   +    L 
Sbjct: 866 SIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLA 925

Query: 577 SHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLR-THSLSN 635
           S +           P  + + +TSP       S   S  T T   +SN T L  T++ S 
Sbjct: 926 SQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSA 985

Query: 636 ADGQYDP 642
           + G   P
Sbjct: 986 STGHTTP 992



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 119/594 (20%), Positives = 213/594 (35%), Gaps = 63/594 (10%)

Query: 98   PSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDD 157
            P  V+D S  ST       ++ T S   G    + +T+P +  S     L    T     
Sbjct: 3536 PLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVST 3595

Query: 158  AKVSEKGRLSPKASQ---------VKRSPSDAGR------------SSGDESKKPLPSSS 196
              V+     SP ++             S +  G             S+G  +  P+  +S
Sbjct: 3596 GHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDAS 3655

Query: 197  RTPTANANSFGFKKQSGSAAGLAM---ITASGVTVTSRSATLGKIPKSSALVSRSAGRKS 253
               T +         S ++ G A    +T+     T  +  L     SSA    +     
Sbjct: 3656 SASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPV 3715

Query: 254  SMDGAQNQDDGY-LALSSRTNLQY-RSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGL 311
            ++  + +  D   L ++S ++     + P P    S    G+ +     D++ +S     
Sbjct: 3716 TIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHAT 3775

Query: 312  PVP---------------KLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKV 356
            P+P                + + S  + G + P  V  T       +    V   +SV  
Sbjct: 3776 PLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVST 3835

Query: 357  NPAAQ-PVSSPAQTSLQPGAKYP--DVASPTLRRLFGGKPTKQVPIATAENMKNSVVISN 413
              A   PV+S +  S       P  D +S +         T    ++T       + +++
Sbjct: 3836 GHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGH--ATPLPVTS 3893

Query: 414  PHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDL----NQSPL-ASSPSSAHSAPSNSL 468
            P +  T        + +   S+G ++PL   N       + +PL  +SPSSA    +++L
Sbjct: 3894 PSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTL 3953

Query: 469  TWGTNASSSSAVSKDGLGFQSVSSLHTSCES----IDISLSSGGVPSHNSSTGLIA-SSK 523
               T+ASS+S      L   S+SS+ T   +     D S +S G  +    T L + S+ 
Sbjct: 3954 P-VTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTG 4012

Query: 524  DDSLTPFVRTNSVKTTLSESDPHLDRNTLPK---KGLRYTPTSQLRTQEDAKEWLRSHSA 580
            D +  P    +S  +  + S P  D +++       L  T TS   T  D      + ++
Sbjct: 4013 DTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSAST-GDTTPLPVTDTS 4071

Query: 581  GGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTT--VTQMSLSNPTMLRTHS 632
                  A   P +  SS ++   T    + L+S +T   T +++S+ T   T S
Sbjct: 4072 SASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVS 4125



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 146/692 (21%), Positives = 243/692 (35%), Gaps = 75/692 (10%)

Query: 12   DSSSVSSGISDTIDNLSTDD----------INTSSSISSYANTPASSRKNLDVQTDAEKH 61
            D+SSVS+G +  +   S+            +  +SS S+   TP          T    H
Sbjct: 2357 DASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATH 2416

Query: 62   SQVER-NSLWSGD-------DVKKSDGGSDSGIKM---EPGSKWRRNPSDVSDESDKSTS 110
              V   +S  +GD       +V  +  G  + + +      S     P   +D S  ST 
Sbjct: 2417 LPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTG 2476

Query: 111  GKKNPVISQTGSWRRGMTAQVGITMPR---TKPSAPAGALKTPG--TGKTDDAKVSEKGR 165
                 +++   S   G T ++ +T P    T  + P     TP   TG T    V+    
Sbjct: 2477 HTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASS 2536

Query: 166  LSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAG-------- 217
            LS + +      S +  S+G  +  P+  +S   T +A        S ++ G        
Sbjct: 2537 LSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVT 2596

Query: 218  ------LAMITASGVTVTSRSATLGKIP-----KSSALVSRS----AGRKSSMDGAQNQD 262
                      T   VT TS ++T    P      SSA    +        SS+       
Sbjct: 2597 DTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATP 2656

Query: 263  DGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKT 322
                + SS +      LP    S+   G       +   S  +  +  LPV     PS  
Sbjct: 2657 LHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPV---TIPSSA 2713

Query: 323  ALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVAS 382
            + G + P  V          + +  V   +SV    A  P+     +S+  G   P +  
Sbjct: 2714 SSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHAT-PLPVTDASSVSTGHATP-LPL 2771

Query: 383  PTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLY 442
             +L  +  G  T  +P+    +         P  +++     D+ +   V  + S+S  +
Sbjct: 2772 TSLSSVSTG-DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDT-TPLPVTDTSSASTGH 2829

Query: 443  SKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLH-TSCESID 501
            + ++ +  +   SS S+ H+ P    T  ++AS+  A         S S  H TS    D
Sbjct: 2830 ATSLPVTDT---SSASTGHATPLPD-TDTSSASTGHATLLPVTDTSSASIGHATSLPVTD 2885

Query: 502  ISLSSGG--VPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDP-HLDRNTLPKKG-- 556
             S  S G   P H +S    +S+     TP   T++   +   ++P H+   +    G  
Sbjct: 2886 TSSISTGHATPLHVTSP---SSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHA 2942

Query: 557  --LRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASP 614
              L  T TS   T       + S S+    DT    P +S SS ++   T    +  +S 
Sbjct: 2943 TPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTP-LPVTSPSSASTGHTTPLPVTDTSSA 3001

Query: 615  TTVTQMSLSNPTMLRTHSLSNADGQYDPYTDS 646
            +T    +L    +  T S S  D    P TD+
Sbjct: 3002 STGQATAL---PVTSTSSASTGDTTPLPVTDT 3030



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 123/572 (21%), Positives = 205/572 (35%), Gaps = 55/572 (9%)

Query: 98   PSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGAL-----KTPGT 152
            P  V+D S  ST    +  ++ T S   G T  + +T   +  +  A +L      +  T
Sbjct: 1088 PLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVST 1147

Query: 153  GKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQS 212
            G T    V++    S   +      S +  S+GD +  P+ S S   T +A        S
Sbjct: 1148 GHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTS 1207

Query: 213  GSAAG----LAMITASGVTVTSRSATLGKIPKSSA-----------LVSRSAGRKSSM-- 255
             ++ G    L +  AS V+    ++    IP +++             S S G+ +S+  
Sbjct: 1208 SASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLV 1267

Query: 256  ---DGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAG-- 310
                     D   L ++S ++     +  P    S + A    +T    +++SS S G  
Sbjct: 1268 TDTSSVSTGDTTPLPVTSTSSASTGHV-TPLHVTSPSSASTGHATPLPVTSLSSASTGDT 1326

Query: 311  LPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ-PVSSPAQT 369
            +P+P +  PS  + G + P  V          +    V   +S     A   PV+S +  
Sbjct: 1327 MPLP-VTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSV 1385

Query: 370  SLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSG 429
            S       P V SP+        P      ++A         S  HAT     +  S S 
Sbjct: 1386 STGDTTPLP-VTSPSSASTGHATPLLVTDTSSA---------STGHATPLPVTDASSVST 1435

Query: 430  SGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQS 489
                S   + P  +        P+  + SSA +  + SL   T+ SS S      L   S
Sbjct: 1436 DHATSLPVTIPSAASTGHTTPLPVTDT-SSASTGQATSLL-VTDTSSVSTGDTTPLPVTS 1493

Query: 490  VSSLHTS-CESIDISLSSGGVPSHNSS---TGLIASSKDDSL-TPFVRTNSVKTTLSESD 544
             SS  T     + ++  S     H +    T L ++S  D++  P    +S  T  +   
Sbjct: 1494 TSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPL 1553

Query: 545  PHLDRNTLP---KKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTA---ANSPFSSGSSV 598
            P  D +++       L  T  S   T       +   S+    DT      SP S+ +  
Sbjct: 1554 PVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGH 1613

Query: 599  TSPSGTRFNFSQLASPTTVTQMSLSNPTMLRT 630
            T+P       S  AS    T + ++N + L T
Sbjct: 1614 TTPLPVTDTSS--ASTGDTTPLPVTNASSLST 1643



 Score = 40.0 bits (92), Expect = 0.017
 Identities = 164/744 (22%), Positives = 264/744 (35%), Gaps = 123/744 (16%)

Query: 12   DSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQ---TDAEKHSQVERNS 68
            D+SS S+G +  +   S   ++T  +      +P+S+          TD    S  +  S
Sbjct: 3077 DASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTS 3136

Query: 69   L--------WSGD-------DVKKSDGGSDSGIKMEPGSK---WRRNPSDVSDESDKSTS 110
            L        ++GD       D   S  G  + + +   S        P  V+D S  ST 
Sbjct: 3137 LPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTG 3196

Query: 111  GKKNPVISQTGSWRRGMTAQVGITMPRTKPSA-----PAGALKTPGTGKTD-----DAKV 160
                  ++   S   G T  V +T   +  +      P   L +  TG T      D   
Sbjct: 3197 HATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISS 3256

Query: 161  SEKGRLSP----KASQVKR---------SPSDAGRSSGDESKKPLPSSSRTPTANANSFG 207
            +  G+ +P      S V           SPS A  S+G  +  P+ S+S   T +A    
Sbjct: 3257 ASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSA--STGHATPLPVTSTSSASTGHATPVP 3314

Query: 208  FKKQSGSAAGLAMITASGVTVTSRSATLGKIP-KSSALVSRSAGRKSSM-----DGAQNQ 261
                S ++ G    T   VT TS ++T    P   ++  S S G  + +       A   
Sbjct: 3315 VTSTSSASTG--HTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTG 3372

Query: 262  DDGYLAL---SSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLRE 318
            D   L +   SS +      LP    S+   G       +S+ S  +  +  LPV    +
Sbjct: 3373 DTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPV---TD 3429

Query: 319  PSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ-PVSSPAQTSLQPGAKY 377
             S  + G + P  V          +    V   +SV    A   PV+  +  S     + 
Sbjct: 3430 ASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRL 3489

Query: 378  P--DVASPTLRRLFGGKPTKQVPIATAEN----MKNSVVISNPHATMTQQGNLDSPS--- 428
            P  D +S +  +      T    ++T +     + ++  +S  HAT     +  S S   
Sbjct: 3490 PVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGD 3549

Query: 429  -------GSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAP-----SNSLTWG----- 471
                    +   S+G ++PL           + SS SS H+ P     ++S++ G     
Sbjct: 3550 TTRLPVTDTSSASTGQATPL--------PVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPL 3601

Query: 472  --TNASSSSAVSKDGLGFQSVSSLHTSCES----IDISLSSGGVPSHNSSTGLIASSKDD 525
              T+ SS+S      L   S SS  T   +     D S  S G  +    T   ++S  D
Sbjct: 3602 HVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGD 3661

Query: 526  SLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLR--TQEDAKEWLRSHSAGGL 583
            + TP   T++   +  ++ P      LP   L    T         DA      H A  L
Sbjct: 3662 T-TPLPVTDTSSASTGQATP------LPVTSLSSVSTGDTTPLPVTDASSASTGH-ATPL 3713

Query: 584  QDTAANSPFSSGSS----VTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQ 639
              T  +S  S+G +    VTSPS      +     T ++  S  + T L     S+A  +
Sbjct: 3714 PVTIPSS-VSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTR 3772

Query: 640  YD---PYTDSRFRNSSMSLDEKSR 660
            +    P TD+    SS S D+ +R
Sbjct: 3773 HATPLPVTDT----SSASTDDTTR 3792



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 69/333 (20%), Positives = 119/333 (35%), Gaps = 41/333 (12%)

Query: 12   DSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWS 71
            D+SSVS+G +  +   ST  ++T  +      +P+S+         A        +S  +
Sbjct: 3861 DTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTG-----HATPVPVTSTSSAST 3915

Query: 72   GDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQV 131
            GD                        P  V++ S  ST       ++   S  RG T+ +
Sbjct: 3916 GDTT----------------------PLPVTNASSLSTGHATPLHVTSPSSASRGDTSTL 3953

Query: 132  GITMPRTKPSA-----PAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGD 186
             +T   +  +      P  +L +  TG T    V++    S   +      S +  S+GD
Sbjct: 3954 PVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGD 4013

Query: 187  ESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKS-SALV 245
             +  P+   S   + +  S      S  + G    T   VT TS ++T    P   +   
Sbjct: 4014 TTPLPVTIPSSASSGHTTSLPVTDASSVSTGHG--TPLPVTSTSSASTGDTTPLPVTDTS 4071

Query: 246  SRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRN---GAGNRSSTSSIDS 302
            S S G  + +      D    +    T L   SL   S  ++      +   +ST S DS
Sbjct: 4072 SASTGHATPLPVT---DTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSDS 4128

Query: 303  NISSKSAGLPVPKLREPSKTALGSSLPGLVNQT 335
             +  ++ G+  P L+        +S P   +QT
Sbjct: 4129 PLKMETPGMTTPSLKTDGGRRTATSPPPTTSQT 4161


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 127/597 (21%), Positives = 210/597 (35%), Gaps = 87/597 (14%)

Query: 284  KSNSRNGAGNRSSTSSIDS-NISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGIS 342
            K+  R   GN +S S++    + SK    P  + R PS        P         K   
Sbjct: 967  KTQKRVKEGNGTSNSTLSGPGLDSK----PGKRSRTPSNDGKSKDKP--------PKRKK 1014

Query: 343  SDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATA 402
            +D E  +  +S    P   P S+    S  PG+       P       G  T  +P  T 
Sbjct: 1015 ADTEGKSPSHSSSNRPFTPPTSTGGSKS--PGSAGRSQTPP-------GVATPPIPKITI 1065

Query: 403  ENMKNSVVISNP--HATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSA 460
            +  K +V++  P  H+  T  G++ S   SG  S  S S   S +   +    +S    +
Sbjct: 1066 QIPKGTVMVGKPSSHSQYTSSGSVSS---SGSKSHHSHSSSSSSSASTSGKMKSSKSEGS 1122

Query: 461  HSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIA 520
             S+  +S  + +  SS S+ SK+        S  +  +     ++  G+ S +SST +  
Sbjct: 1123 SSSKLSSSMYSSQGSSGSSQSKN--------SSQSGGKPGSSPITKHGLSSGSSSTKMKP 1174

Query: 521  SSKDDSL-TPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHS 579
              K  SL  P +   ++  + S      D+   P K +  TP S                
Sbjct: 1175 QGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPS---------------- 1218

Query: 580  AGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQ 639
                  + A SP SSGS  +  SGT  +    +S    +  SLS  T             
Sbjct: 1219 ------SKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKT------------- 1259

Query: 640  YDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQS 699
                       SS S    S + S SGS     +  HGSS     S +      +    +
Sbjct: 1260 ---------PPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNK-----KPSLTA 1305

Query: 700  EIRKLRRELDAS-QEKVSALTTQLTANAHLVAAFEQSLGNMT-IRLQSLTMTAEQKDSEL 757
             I KL+  +  S       L  Q+  + +  +    S  NM+    Q     +++  S++
Sbjct: 1306 VIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKV 1365

Query: 758  NELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSA 817
            +    +++  KK + +      GV         G   +  A + +++   S         
Sbjct: 1366 STSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQM 1425

Query: 818  TSHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSS 874
             S  + GS + S S  K  +     S   A+  +     + S S I E +  + PSS
Sbjct: 1426 ASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSS 1482



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 101/418 (24%), Positives = 143/418 (34%), Gaps = 70/418 (16%)

Query: 110  SGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRL--- 166
            SG + P+++         T  +G    + +     G   +  +G   D+K  ++ R    
Sbjct: 951  SGSQGPLLT---------TGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSN 1001

Query: 167  --SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITAS 224
                K    KR  +D       E K P  SSS  P     S G  K  GSA      T  
Sbjct: 1002 DGKSKDKPPKRKKADT------EGKSPSHSSSNRPFTPPTSTGGSKSPGSAG--RSQTPP 1053

Query: 225  GVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSK 284
            GV          +IPK + +V + +              G  +  S ++    S     K
Sbjct: 1054 GVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGK 1113

Query: 285  SNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSD 344
              S    G+ SS  S     S  S+G    K    S    GSS          + G+SS 
Sbjct: 1114 MKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSS-------PITKHGLSSG 1166

Query: 345  NESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAEN 404
            +      +S K+ P  +P S      + P    P++ SP+  R  GG      P+     
Sbjct: 1167 S------SSTKMKPQGKPSS-----LMNPSLSKPNI-SPSHSRPPGGSDKLASPMKPVPG 1214

Query: 405  MKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAP 464
               S    +P         + S SG   +S  SSS         + S L SS S +   P
Sbjct: 1215 TPPSSKAKSP---------ISSGSGGSHMSGTSSSSGMK-----SSSGLGSSGSLSQKTP 1260

Query: 465  --SNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIA 520
              SNS T     +SSS+ S  G    S  + H S        S G  PS N    L A
Sbjct: 1261 PSSNSCT-----ASSSSFSSSGSSMSSSQNQHGS--------SKGKSPSRNKKPSLTA 1305



 Score = 32.7 bits (73), Expect = 2.7
 Identities = 50/194 (25%), Positives = 78/194 (40%), Gaps = 19/194 (9%)

Query: 807  SSDSVSSINSATSHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEM 866
            SS SVSS  S + HS   S+  S S   K K+       ++ G   S  S+S +S   + 
Sbjct: 1085 SSGSVSSSGSKSHHSHSSSSSSSASTSGKMKS------SKSEGSSSSKLSSSMYS--SQG 1136

Query: 867  TDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDI 926
            +  S  S       G  GS+P+ ++  S+   S  M  + +    +   L    +  +  
Sbjct: 1137 SSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHS 1196

Query: 927  RLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQS 986
            R    S     D+L   M  +       KA++      S GSG S   S  S S+  + S
Sbjct: 1197 RPPGGS-----DKLASPMKPVPGTPPSSKAKS----PISSGSGGSHM-SGTSSSSGMKSS 1246

Query: 987  MGLSQHSLNLTEST 1000
             GL   S +L++ T
Sbjct: 1247 SGLGS-SGSLSQKT 1259


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 179/865 (20%), Positives = 325/865 (37%), Gaps = 86/865 (9%)

Query: 96   RNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKT 155
            R+ S +S  S++S +   +P    T     G T  V +      P +      T   G T
Sbjct: 489  RDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST 548

Query: 156  DDAKVSEKGRL------SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFK 209
                +SEK         SP  + +  S + +G S    +    P S+ T     ++    
Sbjct: 549  TKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 608

Query: 210  KQSGSAAGLAMITASGVTVTSRSATLGKI-PKSSALVSRSAGRKSSMDGAQNQDDGYLAL 268
                S A  +    +  T++  S T   + P+ +   SR    ++++        G L  
Sbjct: 609  LSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEA 668

Query: 269  SSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLR-----EPSKTA 323
            S   +   RS   P  + S  G+  R   S+   +  S +   P P        EPS T+
Sbjct: 669  SMPVHSSTRS---PHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTS 725

Query: 324  LG--SSLP-----------GLVNQTDKEKGISSDNESV----ASCNSVKVNPAAQPVSSP 366
             G  SS+P           GLV ++          +++    +   S +   +    SS 
Sbjct: 726  HGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST 785

Query: 367  AQT-SLQPGAKYPDVASPT-LRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNL 424
              T S  P      V  PT      G   T   P ++  + ++   I++ H++    G +
Sbjct: 786  THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIAS-HSSQDATGTI 844

Query: 425  DSP---SGSGVLSSGSSSPLYSKNVDLNQSP-------LASSPSSAHSAP-SNSLTWGTN 473
              P   + S +L   ++SP+ S +++    P       L+   ++ HS+P S + T    
Sbjct: 845  VLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPA 904

Query: 474  ASSSSAVSKDGLGFQS-VSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVR 532
            +++SS VS++     S   S HT+  +   S ++ G+  H++++     S D +L P   
Sbjct: 905  STTSSGVSEESTTSHSRPGSTHTT--AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAST 962

Query: 533  TNSV---KTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAAN 589
            T  +    TT   S    +   LP      T T+ L     +++    +S+    DT   
Sbjct: 963  TTXLVGEPTTSPISSGSTETTALPGS----TTTAGL-----SEKSTTFYSSPRSPDTTL- 1012

Query: 590  SPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNAD-GQYDPYTDSRF 648
            SP S+ SS  S   T  +    ++ TT    S + P + +  + S++  G  D     R 
Sbjct: 1013 SPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRS 1072

Query: 649  RNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYS------TPEEKCQSEIR 702
              +S    E +   S  GS        + ++  L+ +++ V+S      T      S  R
Sbjct: 1073 TTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTR 1132

Query: 703  K----LRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELN 758
            +      +   +S++ + A  T  +A   L      S  ++     S + T   +  E  
Sbjct: 1133 QGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEEST 1192

Query: 759  ELRKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSAT 818
             +  +        + A++  +G++          G+ Q+       + S+ S  S  S T
Sbjct: 1193 TVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHF---PESSTASGRSEESRT 1249

Query: 819  SHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKS---PKSASSHSDIEEMTDSSLPSSP 875
            SHSS    I S            +S+  + G   +   P+S+++    EE T S   SSP
Sbjct: 1250 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASH--SSP 1307

Query: 876  KLPHNGSTGSTPLLRNSHSNSLISE 900
                  + G TPL  +  ++  I+E
Sbjct: 1308 -----DTNGITPLPAHFTTSGRIAE 1327



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 133/627 (21%), Positives = 229/627 (36%), Gaps = 59/627 (9%)

Query: 102 SDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVS 161
           S  S++ST     P  + T  +       V +  P+T P   A    T   G T  A +S
Sbjct: 139 SGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLS 198

Query: 162 EKGRL---SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSF-------GFKKQ 211
           EK      SP++    R+ S A  +S   S+K   S SR    +  +F       G  ++
Sbjct: 199 EKSTTFYSSPRSPD--RTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQE 256

Query: 212 SGSAAGLAMITASGVTV-TSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALS- 269
           S ++  +   T + ++  T+  ++LG  P+S+   S     K++         G L  S 
Sbjct: 257 STASHSIPGSTDTTLSPGTTTPSSLG--PESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 314

Query: 270 ---SRTNLQYRSLPRPSKSNSRNGAGN--RSSTSSIDSNISSKSAGLPVPKLREPSKTAL 324
              S T   + +L  P+ S +  G     +S  SS D++ +         KL     ++ 
Sbjct: 315 PVHSSTGSPHTTL-SPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 373

Query: 325 GSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPT 384
            S+     + +    G S ++  V S      +P A   + P   S   G      A   
Sbjct: 374 SSTPTTHFSASSTTLGHSEESTPVHS------SPVATATTPPPARSATSGHVEESTA--- 424

Query: 385 LRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSK 444
             R  G   T   P ++  +  +    +   +T   + +  S + +   +S  SS   ++
Sbjct: 425 YHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTE 484

Query: 445 NVDLNQSPLASSPS----SAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESI 500
                 S   S  S    ++HS+P    T    A S+ +V         +SS      ++
Sbjct: 485 TTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL 544

Query: 501 DISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTN---SVKTTLSESDPHLDRNTLPKKGL 557
             S +  G+   +++      S D +  P   T+   S ++T S S P     T      
Sbjct: 545 PGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGST 604

Query: 558 RYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTV 617
                SQ        E   SHS+ G  DT   SP S+ +S   P  T F+    ++ TT+
Sbjct: 605 TMPGLSQ--------ESTASHSSPGPTDTTL-SPGSTTASSLGPEYTTFHSRPGSTETTL 655

Query: 618 ------------TQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRS 665
                         M + + T     +LS A         + F +   S D +    + +
Sbjct: 656 LPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTT 715

Query: 666 GSFRDGFEEVHGSSLSLVSSTSSVYST 692
            +F +     HGS  S+ ++  S  ST
Sbjct: 716 SAFVEPSTTSHGSPSSIPTTHISARST 742



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 130/675 (19%), Positives = 238/675 (35%), Gaps = 84/675 (12%)

Query: 8    TSWDDSSSVSSGISD----------TIDNLSTDDINTSSSISSYANTPASSRKNLDVQTD 57
            T+   +S+ SSG+S+          +    +  D  T+  +S ++ T  SS  + D    
Sbjct: 899  TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL- 957

Query: 58   AEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNP-- 115
                      +   G+          +     PGS      + +S++S    S  ++P  
Sbjct: 958  ----LPASTTTXLVGEPTTSPISSGSTETTALPGST---TTAGLSEKSTTFYSSPRSPDT 1010

Query: 116  VISQTGSWRRGMTAQVGITMPR---TKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQ 172
             +S   +   G++ +   +  R   T  +A  G+   PG  +   A  S  G      S 
Sbjct: 1011 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP 1070

Query: 173  VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSG---SAAGLAMITASGVTVT 229
               + S  G  S      P  + +     N  + G  + S    S+ G    T S    T
Sbjct: 1071 RSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGST 1130

Query: 230  SR---SATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSN 286
            +R   S T    P S          K +M         ++ LS+ ++    S+P    S 
Sbjct: 1131 TRQGESTTFQSWPSS----------KDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSA 1180

Query: 287  SRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNE 346
            S    G    ++++ S+        PV     PS     S+  GLV ++          +
Sbjct: 1181 SSTTFGRSEESTTVHSS--------PVAPATTPSPAR--STTSGLVEESTAYHSSPGSTQ 1230

Query: 347  SV----ASCNSVKVNPAAQPVSSPAQT-SLQPGAKYPDVASPTLRRLFGGKPTKQVPIAT 401
            ++    +S  S +   +    SS   T S  P      V  PT      G       IAT
Sbjct: 1231 TMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGS------IAT 1284

Query: 402  AENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSP------LAS 455
                ++S        +     + D+   + + +  ++S   +++     SP      LAS
Sbjct: 1285 THFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLAS 1344

Query: 456  SPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSS 515
            + ++   +  +++ + ++ S    +S   +   S+S   TS  S   S  +   P+  ++
Sbjct: 1345 TATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTT 1404

Query: 516  TGLIASSKDDSLTPFVRTNSVKTTLSE--------SDPHLDRNTLPKKGLRYTPTSQLRT 567
            +GL      +S T   +  S +TTLS         +      ++ P   L     +    
Sbjct: 1405 SGL----SQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTV 1460

Query: 568  QEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRF----NFSQLASPTTVTQMSLS 623
               ++E    +S+ G  +T A S  S+  S+ S   T F     F+    P T+T   + 
Sbjct: 1461 PGLSEESTTFYSSPGSTETTAFS-HSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIG 1519

Query: 624  NPTMLRTHSLSNADG 638
              +    HS S+A G
Sbjct: 1520 QES-TAFHSSSDATG 1533


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 186/867 (21%), Positives = 303/867 (34%), Gaps = 139/867 (16%)

Query: 167 SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGV 226
           +PK  + K+      RS     ++    SS+     + S   K++  S    +    S  
Sbjct: 184 TPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSK-RKSKD 242

Query: 227 TVTSRSATLGKIPKSS-ALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKS 285
               RS +    PKS  A  S SA   SS D ++++     A +  T L  RS   PS +
Sbjct: 243 KKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRS---PSPA 299

Query: 286 NSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDN 345
           + R G G+  +  S     S++    P    ++PS               DK+K      
Sbjct: 300 SGRRGEGD--APFSEPGTTSTQRPSSPETATKQPSSP---------YEDKDKDK------ 342

Query: 346 ESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENM 405
                    K   A +P  SP ++S  P    P   +P L    GG P    P+AT    
Sbjct: 343 ---------KEKSATRPSPSPERSSTGPE---PPAPTPLLAERHGGSPQ---PLAT---- 383

Query: 406 KNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPS 465
                      T   Q  ++ PS         +SP   ++   +   L  S SS  S PS
Sbjct: 384 -----------TPLSQEPVNPPS--------EASPTRDRSPPKSPEKLPQSSSSESSPPS 424

Query: 466 NSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDD 525
              T  +  +SSS         +S           +IS S     S N S G     K  
Sbjct: 425 PQPTKVSRHASSSP--------ESPKPAPAPGSHREISSSP---TSKNRSHGRAKRDKSH 473

Query: 526 SLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHS------ 579
           S TP  R    ++  +         T  K+G   + + Q R    A+ W RS S      
Sbjct: 474 SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGR 533

Query: 580 ----------------AGGLQDTAANSPFSSGSSVT---SPSGTRFNFSQLASPTTVTQM 620
                             G   +A      S S  T   S S T     +  S T   + 
Sbjct: 534 SRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRR 593

Query: 621 SLS-NPTMLRTHSLSNA-DGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGS 678
           S S  PT  R+ S + A  G+    T +R R+ + S   + R+ SRS + R G       
Sbjct: 594 SRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRS-PVRRRSRSRSPARRSG----RSR 648

Query: 679 SLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGN 738
           S +      S   TP  + +S  R   R    S+ +  A   +  + +           +
Sbjct: 649 SRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGR--SRSRTPRRGRSRSRS 706

Query: 739 MTIRLQSLTMTAEQK-----DSELNELRKTIELLKKQNAAAQAAINGVINTPELNCKGNG 793
           +  R +S + T +++      SE     +T +   + N           ++PE+      
Sbjct: 707 LVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSN-----------SSPEMKKSRIS 755

Query: 794 TAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKS 853
           + +S  L   R  +   +S   S +  S           ++ R    +   K     ++S
Sbjct: 756 SRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS 815

Query: 854 PKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISE---------CMDS 904
             S+S     +  T S    S   PH      TP  + S ++   +E         C +S
Sbjct: 816 RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFES 875

Query: 905 EAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKA-ENDRLKS 963
             +  ++ R   R      +  R+++ +        R++ +R  S   K+KA  + R +S
Sbjct: 876 SPDPELKSRTPSRHSCSGSSPPRVKSSTPP------RQSPSRSSSPQPKVKAIISPRQRS 929

Query: 964 ESQGSGCSRAPSQVSISASPRQSMGLS 990
            S  S  S +PS+V+   +PR+S  +S
Sbjct: 930 HSGSS--SPSPSRVTSRTTPRRSRSVS 954



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 100/414 (24%), Positives = 151/414 (36%), Gaps = 31/414 (7%)

Query: 131  VGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVK----RSPSDAGRSSGD 186
            V +   RT  +A A  L +P T     A V+     +P A  V     R+P+     S  
Sbjct: 2254 VNLADSRTPAAAAAMNLASPRTAVAPSA-VNLADPRTPTAPAVNLAGARTPAALAALSLT 2312

Query: 187  ESKKP-----LPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKS 241
             S  P      PSSSRTP A A++     +S  A     I  S        A+L     +
Sbjct: 2313 GSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMA 2372

Query: 242  SALVSRSAGRKSSMDGAQNQDDGYLALSSRTNL----QYRSLPRPSK-SNSRNGAGNRSS 296
             AL        +++   +     Y  +S RT+     + RS   PS  S SR  +    S
Sbjct: 2373 PALSG------ANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426

Query: 297  TSSIDSNISSKSAGLPVP-KLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVK 355
             SS      S+S   P   + R P  +A       L+ QT    G  S +    +  +  
Sbjct: 2427 PSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486

Query: 356  VNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPH 415
                   +S PA     PG  + DV  P        +P+    +  A+  ++S   S+  
Sbjct: 2487 AGDHNGMLSVPA-----PGVPHSDVGEPPAST-GAQQPSALAALQPAKERRSS---SSSS 2537

Query: 416  ATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNAS 475
            ++ +   +  S S S   S  SSS     ++ +          S   AP  ++  G    
Sbjct: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597

Query: 476  SSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTP 529
             + A  K      S SS  +S  S   S SS    S +SS+   +SS   S +P
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 92/389 (23%), Positives = 157/389 (40%), Gaps = 45/389 (11%)

Query: 115  PVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVK 174
            P ++  G+      A + +T   T P+A       P + +T  A  S    + P+++   
Sbjct: 2293 PAVNLAGARTPAALAALSLTGSGTPPTAA----NYPSSSRTPQAPASAN-LVGPRSAHAT 2347

Query: 175  RSPSDAG-RSSGDESKKPLPSSSRTPT-ANANSFGFKKQSGSAAGLAMITASGVTVTSRS 232
               + AG R++   +   L S+   P  + AN    +    +   ++  T+  +   +RS
Sbjct: 2348 APVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARS 2407

Query: 233  ATLGKIPKSSALVSRSAGRKSSMDGAQN--------QDDGYLALSSRTNLQYRSL----- 279
             T    P  S + S  A   SS  G           QD     + S  + Q R L     
Sbjct: 2408 RTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTT 2467

Query: 280  PRPSKSNSRNGAGNRSSTSSIDSN--ISSKSAGLPVPKLREPSKTALGSSLPGLVN--QT 335
            P     +  +GA   +++S+ D N  +S  + G+P   + EP  +  G+  P  +   Q 
Sbjct: 2468 PVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAST-GAQQPSALAALQP 2526

Query: 336  DKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTK 395
             KE+  SS + S +S +S   + ++   SS + +S   G+  P      L+R+    PT 
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRV--PSPTP 2584

Query: 396  QVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLAS 455
                A  E          P  T  ++    S S S   SS SSS           S  +S
Sbjct: 2585 APKEAVREGRP-------PEPTPAKRKRRSSSSSSSSSSSSSSS-----------SSSSS 2626

Query: 456  SPSSAHSAPSNSLTWGTNASSSSAVSKDG 484
            S SS+ S+ S+S +  +++SSS + +K G
Sbjct: 2627 SSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 176/809 (21%), Positives = 283/809 (34%), Gaps = 125/809 (15%)

Query: 27   LSTDDINTSSSISSYAN-TPASSRKNLDVQTDAEKH------SQVERNSLWSGDDVKKSD 79
            LS + +N  S  S   + +P  S + L   + +E        ++V R++  S +  K + 
Sbjct: 386  LSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAP 445

Query: 80   G-GSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKK-----NPVISQTG------------ 121
              GS   I   P SK R +     D+S   T  ++     +P  ++ G            
Sbjct: 446  APGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGH 505

Query: 122  ------SWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKR 175
                   WRR  +AQ        +    + + + PG  ++ + +   + R + +     R
Sbjct: 506  SRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSR 565

Query: 176  SPSDAGRSSG--------DESKKPL--PSSSRTPT-----ANANSFGFKKQSGSAAGLAM 220
            SP+  GRS            S+ P    S SRTPT     +   +   + +S + A    
Sbjct: 566  SPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS 625

Query: 221  ITASGV------------TVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLAL 268
             T S V            +  SRS T  +  +S +      GR  S   A+         
Sbjct: 626  RTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRT 685

Query: 269  SSRTNLQYRSLPRPSKSNS------------------RNGAG----NRSSTSSIDSNISS 306
             +R        PR  +S S                  R+G+     N+S TS   S  +S
Sbjct: 686  PARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNS 745

Query: 307  ------------KSAGLPVPKLREPSKTALGSSL------PGLVNQTDKEKGISSDNESV 348
                        +S  L  P+ +  S+ +L  SL      P   +QT   +  S  ++  
Sbjct: 746  SPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPK 805

Query: 349  ASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNS 408
            A   +      +     P Q S  P  +    +SP   ++  G P +Q  I + +  + S
Sbjct: 806  AKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH-PKVKSGTPPRQGSITSPQANEQS 864

Query: 409  VVISNPHA-TMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPS----SAHSA 463
            V          +    L S + S    SGSS P    +    QSP  SS       A  +
Sbjct: 865  VTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIIS 924

Query: 464  PSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSK 523
            P      G+++ S S V+      +S S   + C +++  L    +P ++ S    +SS 
Sbjct: 925  PRQRSHSGSSSPSPSRVTSRTTPRRSRSV--SPCSNVESRL----LPRYSHSG---SSSP 975

Query: 524  DDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGL 583
            D  + P        +      P +   T P  G   + +     QE +K+ L     G L
Sbjct: 976  DTKVKPETPPRQSHSGSISPYPKVKAQTPP--GPSLSGSKSPCPQEKSKDSLVQSCPGSL 1033

Query: 584  QDTA-ANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLS---NADGQ 639
               A   S    G S    S  +       SP    +   S+P + ++HS S    +  Q
Sbjct: 1034 SLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD--HRSDTSSPEVRQSHSESPSLQSKSQ 1091

Query: 640  YDPYTDSRFRNSSMSLDEKSRTMSRS--GSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKC 697
              P    R R+SS   +  SR+  R   G F        G S       S   S P    
Sbjct: 1092 TSP-KGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDS 1150

Query: 698  QSEIRKLRRELDASQEKVSALTTQLTANA 726
             S + + R E   S+EK+ AL  Q  A A
Sbjct: 1151 NSLLGQSRLETAESKEKM-ALPPQEDATA 1178



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 81/332 (24%), Positives = 127/332 (38%), Gaps = 41/332 (12%)

Query: 71   SGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQ 130
            SG   + S  GS  G+K  P     R PS    E D S   K  P   +  S R   + +
Sbjct: 1451 SGTPSRHSLSGSSPGMKDIP-----RTPSRGRSECDSSPEPKALPQTPRPRS-RSPSSPE 1504

Query: 131  VG---ITMPRTKPSAPAGA-----LKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGR 182
            +    +T  R +  + +        +TP  G+   +  S++  + P AS  +RS SD+  
Sbjct: 1505 LNNKCLTPQRERSGSESSVDQKTVARTP-LGQRSRSGSSQELDVKPSASPQERSESDSSP 1563

Query: 183  SSGDESKKPLPSSSR---TPTANANS--FGFKKQSGSA--------AGLAMITASGVTVT 229
             S  +++ PL   SR   +P  ++ S     + +SGS+        A     + S  +  
Sbjct: 1564 DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPE 1623

Query: 230  SRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDG--YLALSSRTNLQYRSLPRPSKSNS 287
             ++     +P+ S   S S GR  S +G+ + +    +   S       RS P P K+ S
Sbjct: 1624 PKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEP-KTKS 1682

Query: 288  RNGAGNRSSTSSID-------SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKG 340
            R     RSS SS +       S  S  ++  P  + R P +       P + +    EK 
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS---PSVSSPEPAEKS 1739

Query: 341  ISSDNESVASCNSVKVNPAAQPVSSPAQTSLQ 372
             SS     AS    K         SP    LQ
Sbjct: 1740 RSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771



 Score = 38.9 bits (89), Expect = 0.038
 Identities = 67/292 (22%), Positives = 107/292 (36%), Gaps = 30/292 (10%)

Query: 14   SSVSSGISDTIDNL--STDDINTSSSISSYANTPASSRKN-----LDVQTDAEKHSQVER 66
            S V S  SD    L   T  +  S S+SS A    +S        L V      HS V  
Sbjct: 2449 SPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDV-- 2506

Query: 67   NSLWSGDDVKKSDGGSDSGIK-MEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRR 125
                 G+    +     S +  ++P  + R + S  S  S  S+S   +   S +GS   
Sbjct: 2507 -----GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGS--- 2558

Query: 126  GMTAQVGITMPRTKPSAPAGALK-TPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSS 184
              +   G ++    P  P  ALK  P         V E     P  ++ KR  S +  SS
Sbjct: 2559 SSSDSEGSSL----PVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS 2614

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
               S     SSS + +++++S      S S++        G     + A+  K P     
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE-- 2672

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSS 296
              RS   +  +D  ++      +LS     + R  P+PS  + ++ +  R S
Sbjct: 2673 -RRSRSPRKPIDSLRDS----RSLSYSPVERRRPSPQPSPRDQQSSSSERGS 2719



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 58/278 (20%), Positives = 100/278 (35%), Gaps = 32/278 (11%)

Query: 113  KNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLS----- 167
            ++PV S      R + AQ       T P A + +L +     T  +     G LS     
Sbjct: 2448 RSPVPSAFSDQSRCLIAQ-------TTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPG 2500

Query: 168  --------PKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLA 219
                    P AS   + PS        + ++   SSS + +++++S      S S+   +
Sbjct: 2501 VPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSS 2560

Query: 220  MITASGVTVTSRSATLGKIPKSSALVSRSA--GRKSSMDGAQNQ---DDGYLALSSRTNL 274
              +            L ++P  +     +   GR      A+ +        + SS ++ 
Sbjct: 2561 SDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSS 2620

Query: 275  QYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQ 334
               S    S S+S + + + SS+SS  S   +K     +PK   P K       PG    
Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPP-----PGERRS 2675

Query: 335  TDKEKGISS--DNESVASCNSVKVNPAAQPVSSPAQTS 370
                K I S  D+ S++     +  P+ QP     Q+S
Sbjct: 2676 RSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSS 2713



 Score = 31.2 bits (69), Expect = 7.8
 Identities = 46/204 (22%), Positives = 70/204 (34%), Gaps = 15/204 (7%)

Query: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPAS---SRKNLDVQTDAEKHSQV 64
            +S   SSS SS  S +  + S+    +SSS S  ++ P     + K +   T A K + V
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA-V 2590

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWR 124
                       K+    S S       S    + S  S  S  S+S   +   S + S  
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650

Query: 125  RGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDA---------KVSEKGRLSPKAS--QV 173
                    +  P +    P G  ++    K  D+            E+ R SP+ S    
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710

Query: 174  KRSPSDAGRSSGDESKKPLPSSSR 197
            + S S+ G   G       PS  R
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKR 2734


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 219/1107 (19%), Positives = 403/1107 (36%), Gaps = 165/1107 (14%)

Query: 8    TSWDDSS---SVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQV 64
            T+W  +S   ++SSG S   +  ST    T   + S A+T A+ ++N + +T   +++  
Sbjct: 2062 TTWPSTSLSEALSSGHSGVSNPSST---TTEFPLFSAASTSAAKQRNPETETHGPQNTAA 2118

Query: 65   ERNSLWSGDDVKKSDGGSDSGIKME-PGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSW 123
               +  +      S+    + I  E P      + SDVS  + +ST+   NP +    S 
Sbjct: 2119 STLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTA---NPSLGTASSA 2175

Query: 124  RRGMTAQVGITMPRT-----------KPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQ 172
               +T  + +    +             S P G+  T  T  +     +    LS  AS 
Sbjct: 2176 GTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGPPGLSTVASD 2235

Query: 173  VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRS 232
            V  +PSD   S    S  P P +  T  ++      +K + S   ++ +T     +TSR 
Sbjct: 2236 VIDTPSDGAESIPTVSFSPSPDTEVTTISHFP----EKTTHSFRTISSLTHE---LTSRV 2288

Query: 233  ATLGKIPKSSALVSRSAGRKSSMDGAQNQ-------------------DDGYLALSSRTN 273
              +     SSA+ ++  G   S+   + +                   +   ++L + T 
Sbjct: 2289 TPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETT 2348

Query: 274  LQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTAL----GSSLP 329
            ++   +    K+N      + SS+SS   N S  S+ + V K    S T++     SS P
Sbjct: 2349 VKTSDILDARKTNE---LPSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSP 2405

Query: 330  GLVN-------------QTDKEKGISSDNESVASCNSVKVNPAAQP---VSSPAQTSLQP 373
             L +              T     +SS+  S+   ++V   P+  P   ++ P +TS   
Sbjct: 2406 SLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSAL 2465

Query: 374  GAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNP-HATMTQQGNL-------- 424
             A    V      R F    +            NSVV S P   T T  G+         
Sbjct: 2466 LAWSRPV------RTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGF 2519

Query: 425  --DSPSG--------------------SGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHS 462
               SP+G                    S  + +GSS+   +  +  ++S    S     +
Sbjct: 2520 LKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPT 2579

Query: 463  APSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASS 522
             P++   W T+A+  S +        +++S     ++I  S  S   PS   STG ++ +
Sbjct: 2580 TPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVS-TPPSKFPSTGTLSGA 2638

Query: 523  KDDSL---TPFVRTNSVKTTLS-----ESDPHL-----DRNTLPKKGLRYTPTSQ----- 564
               +L   TP +   + + T S     +S P +        T+P+  L  + TS      
Sbjct: 2639 SFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALV 2698

Query: 565  LRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSN 624
            L+T  +    +   +  G+ ++  +   +S S + +P  T +  S   + +T+     + 
Sbjct: 2699 LKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLP----AG 2754

Query: 625  PTMLRTHSLSNADGQYDPYTDSRF---RNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLS 681
             T     S S+ + +     DS     R S M L   S+ M+ SG  R G    H +   
Sbjct: 2755 TTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSG--STHSTGTK 2812

Query: 682  LVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKV------------SALTTQLTANAHLV 729
              SS     +  E    SEI   R  L A+Q               S L T ++A++   
Sbjct: 2813 TFSSLPLTMNPGEVTAMSEITTNR--LTATQSTAPKGIPVKPTSAESGLLTPVSASSSPS 2870

Query: 730  AAFEQ-SLGNMTIRLQSLTMTAE--------QKDSELNELRKTIELLKKQNAAAQAAING 780
             AF   +    T  +   T+T E         K + L    +++  +   +A+   A + 
Sbjct: 2871 KAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDAS--TASSS 2928

Query: 781  VINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWL 840
            +  +PE N +      +  +      S+    +   + S S  G      +       + 
Sbjct: 2929 LSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYA 2988

Query: 841  RSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISE 900
              S        K+  + +S S   ++T  +L S+ +   +GS+ S   L      S +S 
Sbjct: 2989 SESMSYP-DPSKASSAMTSTSLASKLT--TLFSTGQAARSGSSSSPISLSTEKETSFLSP 3045

Query: 901  CMDSEAETVMQLRNELRDKEMKLTDIRLEA--LSSAHQLDQLREAMNRMQSEIEKLKAEN 958
               +  +T + L   +  +   L  ++  A  LS    L+  +E    + S     + E 
Sbjct: 3046 TASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEG 3105

Query: 959  DRLKSESQGSGCSRAPSQVSISASPRQ 985
               ++++     S  P+ +   +SP +
Sbjct: 3106 TTAETQTLTFTPSETPTSLLPVSSPTE 3132



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 213/1029 (20%), Positives = 379/1029 (36%), Gaps = 179/1029 (17%)

Query: 9    SWDDSSSVSSGIS-DTIDNLSTDDINTSSSISSYA----NTPASSRKNLDVQTDAEKHSQ 63
            S  D  ++S  IS + I  LST  I T S+ S+      +  A+S   L + T       
Sbjct: 8462 SGPDQFTISPDISTEAITRLSTSPIMTESAESAITIETGSPGATSEGTLTLDTST----- 8516

Query: 64   VERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVS-------DESDKSTSGKKNPV 116
                + WSG     S G S S    E  +   R P DV        +E+   +S   +P 
Sbjct: 8517 ---TTFWSGTHSTASPGFSHS----EMTTLMSRTPGDVPWPSLPSVEEASSVSSSLSSPA 8569

Query: 117  ISQTGSWRRGMTAQVGITMPRTKPSAP--AGALKTPGTGKTDDA-KVSEKGRLSPKASQV 173
            ++ T  +          T+P +  S+P    AL T G  KT D  + S +   S   +  
Sbjct: 8570 MTSTSFFS---------TLPESISSSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPNLS 8620

Query: 174  KRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSA 233
              S      S   + ++ +  SS TP  N  +  +K  S S+    ++T    +  + ++
Sbjct: 8621 STSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTS 8680

Query: 234  TLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGN 293
            TLG    +S   S  A  ++ M             +  T+     L   S S   + A  
Sbjct: 8681 TLG---NTSVSTSTPAFPETMM-------------TQPTSSLTSGLREISTSQETSSATE 8724

Query: 294  RSSTSSIDSNISSKSAGLPVPKLREPSKT---ALG-SSLPGLVNQTDKEKGISSDNESVA 349
            RS++ S          G+P     + S+T   +LG +S PG    T     IS +     
Sbjct: 8725 RSASLS----------GMPTGATTKVSRTEALSLGRTSTPGPAQST-----ISPE----I 8765

Query: 350  SCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSV 409
            S  ++         +  A+ ++ P   +   +S       G         A+     ++ 
Sbjct: 8766 STETITRISTPLTTTGSAEMTITPKTGHSGASSQ------GTFTLDTSSRASWPGTHSAA 8819

Query: 410  VISNPHATMTQ-----QGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPS-SAHSA 463
               +PH+ MT        ++  PS   V  +   S L S +   + SPL S+PS S+HS+
Sbjct: 8820 THRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSS 8879

Query: 464  P--------------SNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLS---- 505
            P              ++ L       ++S  S +    +S+++   + E+  I LS    
Sbjct: 8880 PLRVTSLFTPVMMKTTDMLDTSLEPVTTSPPSMNITSDESLATSKATMETEAIQLSENTA 8939

Query: 506  -------SGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLR 558
                   S     ++S  GL   SK  S  P V ++++K  +S + P     T  +    
Sbjct: 8940 VTQMGTISARQEFYSSYPGLPEPSKVTS--PVVTSSTIKDIVSTTIPASSEITRIEMEST 8997

Query: 559  YTPTSQLRTQEDAKEWLRSHSA---------GGLQDTAANSPFSSGSSVTSPSGTRFNFS 609
             T T   R    ++E    HSA              T  +S     SS   PS  +   S
Sbjct: 8998 STLTPTPRETSTSQE---IHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTMS 9054

Query: 610  QLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGS-F 668
            Q  S   +T++S S P    +  ++       P   SR    +++LD  +  MS + S  
Sbjct: 9055 QDISTEVITRLSTS-PIKTESTEMTITTQTGSPGATSR---GTLTLDTSTTFMSGTHSTA 9110

Query: 669  RDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHL 728
              GF   H    +L+S T             E         AS    S  +  +T+++ +
Sbjct: 9111 SQGFS--HSQMTALMSRTPGDVPWLSHPSVEE---------ASSASFSLSSPVMTSSSPV 9159

Query: 729  VAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELN 788
             +    S+ + ++ + SL  +          L KT ELL            G  + PE +
Sbjct: 9160 SSTLPDSIHSSSLPVTSLLTSG---------LVKTTELL------------GTSSEPETS 9198

Query: 789  CKGNGTAQSADLRIRRQHSSDS-----VSSINSATSHSSVGSNIESDSKKKKRKNWLRSS 843
               N ++ SA++    + ++D+      + + S  +H S  S++ +DS   K  + +  +
Sbjct: 9199 SPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHES-PSSVLADSVTTKATSSMGIT 9257

Query: 844  FKQAFGKKKSPKSASSHSDIEEM-TDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECM 902
            +    G      S  + SD   + T S L  +P L     +  T    ++   S +   +
Sbjct: 9258 YPT--GDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEET---SSATEKSTVLSSV 9312

Query: 903  DSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLK 962
             + A T +     +      +       +SS    D   E + R+ + + + ++ +  + 
Sbjct: 9313 PTGATTEVSRTEAISSSRTSIPGPAQSTMSS----DTSMETITRISTPLTRKESTDMAIT 9368

Query: 963  SESQGSGCS 971
             ++  SG +
Sbjct: 9369 PKTGPSGAT 9377



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 201/997 (20%), Positives = 356/997 (35%), Gaps = 184/997 (18%)

Query: 13   SSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSG 72
            +S ++SG++ T D L       ++S ++ ++T        +V TD EK       ++   
Sbjct: 8002 TSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEILATSEVTTDTEKTHPSSNRTV--- 8058

Query: 73   DDVKKSDGGSDSGIKMEPGSKWRR--NPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQ 130
             DV  S  G +S   +   S+  +  +P  ++   + ++     P   +T   +   T+ 
Sbjct: 8059 TDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSS 8118

Query: 131  VGI----------TMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKA-SQVKRSPSD 179
            + +          T   T+ S     + T  T +    +V+   R S    +Q+  SP  
Sbjct: 8119 LTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSP-- 8176

Query: 180  AGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIP 239
                +  E+   LP+SS   T +A     K Q+         T         S T   + 
Sbjct: 8177 ---ETSTETITRLPTSS-IMTESAEMM-IKTQTDPPGS----TPESTHTVDISTTPNWVE 8227

Query: 240  KSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSS 299
              S +  R +   S M    ++  G +   S++     S+   S ++S       +S S 
Sbjct: 8228 THSTVTQRFS--HSEMTTLVSRSPGDMLWPSQS-----SVEETSSASSLLSLPATTSPSP 8280

Query: 300  IDSNI--SSKSAGLPVPKLREPSKTALGSSLPGLVNQTD-----KEKGISS--------- 343
            + S +     SA LPV  L            PGLV  TD     +E G SS         
Sbjct: 8281 VSSTLVEDFPSASLPVTSLLN----------PGLVITTDRMGISREPGTSSTSNLSSTSH 8330

Query: 344  ----------DNESVASCNSVKVNPAAQPVSS-PAQTSLQPGAKYPDVASPTLRRLFGGK 392
                      D E +       V      +S   +Q+S+   ++ P   SP       G+
Sbjct: 8331 ERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGE 8390

Query: 393  PTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSK-----NVD 447
             +  V I+T++  + S +   P +++T  G  ++ S   + S+   S + S+       +
Sbjct: 8391 TS--VSISTSDFFETSRIQIEPTSSLT-SGLRETSSSERISSATEGSTVLSEVPSGATTE 8447

Query: 448  LNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSG 507
            ++++ + SS  ++ S P          + S  +S + +   S S + T      I++ +G
Sbjct: 8448 VSRTEVISSRGTSMSGPD-------QFTISPDISTEAITRLSTSPIMTESAESAITIETG 8500

Query: 508  GVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRT 567
               + +  T     + D S T F   +   +T S    H +  TL  +     P   L +
Sbjct: 8501 SPGATSEGT----LTLDTSTTTF--WSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPS 8554

Query: 568  QEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNF------SQLASPTTVTQMS 621
             E+A                     S  SS++SP+ T  +F      S  +SP  VT + 
Sbjct: 8555 VEEAS--------------------SVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALL 8594

Query: 622  LSNPT----MLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHG 677
               P     MLRT S        +P T S    SS S    +  ++ S   +D  E++H 
Sbjct: 8595 TLGPVKTTDMLRTSS--------EPETSSPPNLSSTS----AEILATSEVTKDR-EKIHP 8641

Query: 678  SSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLG 737
            SS + V +  +V              + + L  S      +TT+ T+      A   +LG
Sbjct: 8642 SSNTPVVNVGTV--------------IYKHLSPSSVLADLVTTKPTS----PMATTSTLG 8683

Query: 738  NMTIRLQS-------LTMTAEQKDSELNELRKTIELLKKQNAAAQ------AAINGVINT 784
            N ++   +       +T       S L E+  + E       +A        A   V  T
Sbjct: 8684 NTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRT 8743

Query: 785  PELNCKGNGTAQSADLRIRRQHSSDSVSSINS--------------ATSHSSVGSNIESD 830
              L+     T   A   I  + S+++++ I++               T HS   S     
Sbjct: 8744 EALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFT 8803

Query: 831  SKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLR 890
                 R +W  +    +    +SP S  +        D S PS P +       S   L 
Sbjct: 8804 LDTSSRASWPGT---HSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVSLS 8860

Query: 891  NSHSNS-LISECMDSEAETVMQLRNELRDKEMKLTDI 926
               S S L S   +S   + +++ +      MK TD+
Sbjct: 8861 AVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDM 8897



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 128/625 (20%), Positives = 229/625 (36%), Gaps = 98/625 (15%)

Query: 344  DNESVASCNS-VKVNPAAQPV--SSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIA 400
            DN +  S +S V +  A  P+  SSPA+TS     +     S T      G     V  A
Sbjct: 1632 DNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALER---RSSTATVSMAGTMGLLVTSA 1688

Query: 401  TAENMKNSVV-ISNPHATMTQQGNLDSPSGSG--------VLSSGSSSPLYSKNVDLNQS 451
               ++  S+  +S+  +  T +G  DS  GS            S S  P Y++   ++ S
Sbjct: 1689 PGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTS 1748

Query: 452  -PLASSP----------------------------SSAHSAPSNSLTWGTNASSSSAVSK 482
             PL SSP                            SSA +  S++    T   S+    K
Sbjct: 1749 IPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGK 1808

Query: 483  DGLGFQSVSSLHTSCESID----ISLSSGGVPS-----------HNSSTGLIASSKDDSL 527
            + L   S+  L +   S++    ISL+    P+           H SS G +A+ +  + 
Sbjct: 1809 EKLRTASMD-LPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDRSLN- 1866

Query: 528  TPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTA 587
            T   R + ++     S   L         + YT  S++ +    +      SA G + T 
Sbjct: 1867 TGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRP---ETSAPGAETTL 1923

Query: 588  ANSPFSSGSSVTSPSG---------TRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADG 638
             ++P +   S+T P           T        +   +T   ++ PT++ T +     G
Sbjct: 1924 TSTPGNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTST-----G 1978

Query: 639  QYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPE-EKC 697
              +  T      SS  +  ++++     S        H +S+S  SSTSS YS+   E  
Sbjct: 1979 TIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESL 2038

Query: 698  QSEIRKLRRELDASQEKVSALTTQL---TANAHLVAAFEQSLGNMTIRLQSLTMTAEQKD 754
             S I +         +  ++L T     T+ +  +++    + N +       + +    
Sbjct: 2039 DSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAAST 2098

Query: 755  SELNELRKTIELLKKQNAAAQ------AAINGVINTPELNCKGNGTAQSADLRIRRQHSS 808
            S   +     E    QN AA       +++ G+  TP     G   +    L +     S
Sbjct: 2099 SAAKQRNPETETHGPQNTAASTLNTDASSVTGLSETP----VGASISSEVPLPMAITSRS 2154

Query: 809  DSVSSINSATSHSSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSAS----SHSDIE 864
            D     + +T++ S+G+   + +K  +  +   S    +F   K P + S    SH    
Sbjct: 2155 DVSGLTSESTANPSLGTASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTN 2214

Query: 865  EMTDSSLPSSPKLPHNGSTGSTPLL 889
              T++S+P +   P   ST ++ ++
Sbjct: 2215 --TETSIPVNSAGPPGLSTVASDVI 2237



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 130/641 (20%), Positives = 221/641 (34%), Gaps = 123/641 (19%)

Query: 12   DSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWS 71
            D +++ S I   +   S   ++ +SS SS+ ++PA +  +L   T  E        SL +
Sbjct: 5014 DVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLT 5073

Query: 72   GDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKN-----PVISQTGSWRRG 126
               VK +D       ++EP +    N S  SD+   ++   K+     P I+        
Sbjct: 5074 SGLVKITD---ILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSIN-------- 5122

Query: 127  MTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKV--SEKGRLSPKASQVKRSPSDAGRSS 184
             T +  +    +   + + AL    T K     V  +  G  +P  S      S+     
Sbjct: 5123 -TEETNVKANNSGHESHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIK 5181

Query: 185  GDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSAL 244
             + +    P    T T+  +SF                      T  S  L K+P  +  
Sbjct: 5182 REPTYFLTPRLRETSTSQESSF---------------------PTDTSFLLSKVPTGTIT 5220

Query: 245  VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNI 304
               S G  SS                       S P   KS                S+I
Sbjct: 5221 EVSSTGVNSS--------------------SKISTPDHDKSTVPPDTFTGEIPRVFTSSI 5260

Query: 305  SSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVS 364
             +KSA + +     P ++A  S+LP   + T  + G  S                     
Sbjct: 5261 KTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHS--------------------- 5299

Query: 365  SPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNL 424
                 ++  G  Y +V   TL  +  G  +        E    S ++S+P   MT    +
Sbjct: 5300 -----TVTQGFPYSEVT--TLMGMGPGNVSWMTTPPVEETSSVSSLMSSP--AMTSPSPV 5350

Query: 425  DSPSGSGVLSSGSSSPLYSKNVDLNQSPL--ASSPSSAHSAPSNSLTWGTNASSSSAVSK 482
             S S   + SS         +V +  + +   +SP S  S+P N     +      A  K
Sbjct: 5351 SSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPN---LSSITHERPATYK 5407

Query: 483  DGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSV--KTTL 540
            D    ++     T+    ++  S  G   H S + ++A S+    TP + T S    T++
Sbjct: 5408 DTAHTEAAMHHSTNTAVTNVGTSGSG---HKSQSSVLADSETSKATPLMSTTSTLGDTSV 5464

Query: 541  SESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAA----NSPFS--- 593
            S S P++ +            T+Q++T+  A    R   +   + T++    N+ FS   
Sbjct: 5465 STSTPNISQ------------TNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVP 5512

Query: 594  ----SGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRT 630
                + +S T  S +R + S L  PT    +S    T L T
Sbjct: 5513 TGAITQASRTEISSSRTSISDLDRPTIAPDISTGMITRLFT 5553



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 188/952 (19%), Positives = 347/952 (36%), Gaps = 110/952 (11%)

Query: 13   SSSVSSGISDTIDNLSTDDINTSS--SISSYANTPASSRKNLDVQTDAEKHSQVERNSLW 70
            +SS  + I  T     + D +T S   +S++A    S  + +  QT    H    + +L 
Sbjct: 6404 TSSSRTSIQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGP--HRATSQGTLT 6461

Query: 71   SGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMT-- 128
                +  S  G+ S   M  G   + + S ++    +  SG   P + +T S    ++  
Sbjct: 6462 WDTSITTSQAGTHSA--MTHGFS-QLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLP 6518

Query: 129  -----AQVGITMPRTKPSAPA--GALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAG 181
                 + V  T+P ++PS+P    +L T G  KT D   S         S   + P+ + 
Sbjct: 6519 AITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSE 6578

Query: 182  RSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKS 241
                 E   P   S+     N  +   +K+S S+       +    VTS   T   I   
Sbjct: 6579 DIKDTEKMYP---STNIAVTNVGTTTSEKESYSS---VPAYSEPPKVTSPMVTSFNI--R 6630

Query: 242  SALVSRSAGRKSSMDGAQNQDDGYLALSSR-TNLQYRSLPRPSKSNSRNGAGNRSSTSSI 300
              +VS S    S +   + +    LA   + T+     +    KS   +     ++ +S 
Sbjct: 6631 DTIVSTSMPGSSEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSR 6690

Query: 301  DSNISSKSAGLPVPKLREPSKTALGSSLPGL-----VNQTDKEKGISSDNESVASCNSVK 355
                SS+   +P P     S       +P L     + ++     I+     + S +   
Sbjct: 6691 TEVASSRRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGT 6750

Query: 356  VNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPH 415
                    SS A T      ++P     T+        +  +P +  +   +S ++ +P 
Sbjct: 6751 FTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPA 6810

Query: 416  ATMTQQGNLDSPSGSGVL------SSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLT 469
             T        SP  S  L      +    + L + ++ +    L +SP    S+P N   
Sbjct: 6811 MT--------SPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNL-- 6860

Query: 470  WGTNASSSSAVSKDGLGFQSVSSLH--TSCESIDISLSSGGVPSHNSSTGLIASSKDDSL 527
                +S+S  +        ++ ++H  TS  + ++  +S G   H S + ++A S+    
Sbjct: 6861 ----SSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSG---HGSQSSVLADSEKTKA 6913

Query: 528  TPFVRTNSV--KTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQD 585
            T  + T S    TT+S S       T  K+   Y+ T  LR                   
Sbjct: 6914 TAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRE----------------TS 6957

Query: 586  TAANSPFSSGSSVT---SPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDP 642
             + N+ FS+ +S+     P+GT    S+       T+++ S  T +   S S    +   
Sbjct: 6958 ISQNASFSTDTSIVLSEVPTGTTAEVSR-------TEVTSSGRTSIPGPSQSTVLPEIST 7010

Query: 643  YTDSR-FRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKC-QSE 700
             T +R F + +M+   +    +++G      ++      S   S +  +ST  ++   SE
Sbjct: 7011 RTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSE 7070

Query: 701  IRKLRR--------ELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQ 752
            +  L          +   S E  S+L + L+  A        S   +TI    L +T+  
Sbjct: 7071 MTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLL 7130

Query: 753  KDSEL---NELRKTIELL-----KKQNAAAQAAING--VINTPELNCKGNGTAQSADLRI 802
              S +   + L  + EL+     K  + + +    G    NT  ++   N  A + ++  
Sbjct: 7131 TSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPS 7190

Query: 803  RRQHSSDSV---SSINSATSHSSVGSNIESDSKKKKRKNWLRSS-FKQAFGKKKSPKSAS 858
                S  S    S  + ATS   + S  E  +      ++L +S  ++      SPK   
Sbjct: 7191 SGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRE 7250

Query: 859  SHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVM 910
            + S +E  T S++ +S  L    S G+T  +  +   S     +   AE+ M
Sbjct: 7251 TGSSVE--TSSAIETSAVL-SEVSIGATTEISRTEVTSSSRTSISGSAESTM 7299



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 149/707 (21%), Positives = 263/707 (37%), Gaps = 132/707 (18%)

Query: 12   DSSSVSSGIS-DTIDNLSTDDINTSSS---ISSYANTP-ASSRKNLDVQTDAEKHSQVER 66
            D S++S  IS + I  LST  I T S+   I++   +P A+SR  L + T          
Sbjct: 9049 DQSTMSQDISTEVITRLSTSPIKTESTEMTITTQTGSPGATSRGTLTLDTST-------- 9100

Query: 67   NSLWSGDDVKKSDGGSDSGI----KMEPGS-KWRRNPSDVSDESDKSTSGKKNPVISQTG 121
             +  SG     S G S S +       PG   W  +PS   +E+  ++    +PV++ + 
Sbjct: 9101 -TFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPS--VEEASSASFSLSSPVMTSS- 9156

Query: 122  SWRRGMTAQVGITMPRT--KPSAPAGALKTPGTGKT-------DDAKVSEKGRLSPKASQ 172
                   + V  T+P +    S P  +L T G  KT        + + S    LS  +++
Sbjct: 9157 -------SPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTSAE 9209

Query: 173  V---KRSPSDAGR-------SSGDESKKPLPSSSRTPTANA-NSFGFKKQSGSAAGLAMI 221
            +       +D  +       +SG   + P    + + T  A +S G    +G    L   
Sbjct: 9210 ILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDTNVLTST 9269

Query: 222  TASGVTVTSRSATLGKIPKSSALVSRSAGRKSSM------------DGAQNQDDGYLALS 269
             A   + TSR  T  K+  +  L+  S   ++S              GA  +     A+S
Sbjct: 9270 PA--FSDTSRIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAIS 9327

Query: 270  SRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPV-PKLREPSKTALGS-- 326
            S       S+P P++S   +     + T         +S  + + PK      T+ G+  
Sbjct: 9328 SSRT----SIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFT 9383

Query: 327  -------SLPGLVNQTDKE-------KGISSDNESVASCNSVKV---NPAAQPVSSPAQT 369
                   S PG  + T +          +S   E V+  + + V   +P +  VSS + T
Sbjct: 9384 LDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVT 9443

Query: 370  SLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVI---------SNPHATMTQ 420
            S  P    P  +S +        P     + T+  MK + ++         S P+  +T 
Sbjct: 9444 SPSPLYSTPSGSSHS-------SPVPVTSLFTSIMMKATDMLDASLEPETTSAPNMNITS 9496

Query: 421  QGNL---------------DSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPS 465
              +L               ++ + S V ++ ++  LYS       SP  S P+   S   
Sbjct: 9497 DESLAASKATTETEAIHVFENTAASHVETTSATEELYSS------SPGFSEPTKVISPVV 9550

Query: 466  NSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDD 525
             S +   N  S++     G+    + S+ +    +  + +S  + S ++ T  +      
Sbjct: 9551 TSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITS-STETSTVLYKMPS 9609

Query: 526  SLTPFVRTNSVKTTLSESDPHLDRNTLP----KKGLRYTPTSQLRTQEDAKEWLRSHSAG 581
              TP V    V  +   S P   ++T+      + +    TS + T E A+  + + +  
Sbjct: 9610 GATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMT-ESAEITITTQTGY 9668

Query: 582  GLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTML 628
             L  +    P   G+S+T  SGT    SQ  S + +T +    P  L
Sbjct: 9669 SLATSQVTLPL--GTSMTFLSGTHSTMSQGLSHSEMTNLMSRGPESL 9713



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 132/656 (20%), Positives = 222/656 (33%), Gaps = 103/656 (15%)

Query: 14    SSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSGD 73
             S ++SG   T  +L T  +  +++ SS  +T        D  + A+  S           
Sbjct: 10163 SHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSKTDFTSSAKTSSP---------- 10212

Query: 74    DVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGI 133
                             P S++   P D+    + S S  ++  I+     R  M+     
Sbjct: 10213 -------------DWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFTMSVTEST 10259

Query: 134   ------TMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDE 187
                    +P  +  +    + +     T  A       +S   S   R+ S  G ++   
Sbjct: 10260 HHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLST 10319

Query: 188   SKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTV--------TSRSATLGKIP 239
               + LPSS  TP   ++S      S +   L  IT+S  T         T  S T G++ 
Sbjct: 10320 IAESLPSS--TPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLV 10377

Query: 240   KSSAL-VSRSAGRKSS---MDGAQNQD-------DGYLALSSRTNLQYRSLPRPSKSNSR 288
               S L  S   GR SS   +D    +          Y   S  T L          +   
Sbjct: 10378 MVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGIMEHITKIP 10437

Query: 289   NGAGNRSSTSSIDSNISSKSAGLPV------PKLREPSKTALGSSLPGLVNQTDKEKGIS 342
             N A +R +   +    +S S   P        K  E + TAL ++   L           
Sbjct: 10438 NEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTAL----------- 10486

Query: 343   SDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATA 402
                 S A+  +    P    ++ P   S+Q  +  P     T   +F   P     +AT+
Sbjct: 10487 -KTTSRATLTTSVYTPTLGTLT-PLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATS 10544

Query: 403   ENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHS 462
                + S  +  P  T +        + S V  SG+            +SP+  +   + S
Sbjct: 10545 LGAETSTAL--PRTTPSVFNRESETTASLVSRSGAE-----------RSPVIQTLDVSSS 10591

Query: 463   APSNSLTWGTN-ASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIAS 521
              P  + +W  + A +   VSK    F      H+  +++  + +S G    ++    I+ 
Sbjct: 10592 EPDTTASWVIHPAETIPTVSKTTPNF-----FHSELDTVSSTATSHGADVSSAIPTNISP 10646

Query: 522   SKDDSLTPFVRTNSVKT-----TLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLR 576
             S+ D+LTP V  +   T     TL++S    +  T        T ++  RT  +      
Sbjct: 10647 SELDALTPLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNF----- 10701

Query: 577   SHSAGGLQDTAANSPFSSGSS-----VTSPSGTRFNFSQLASPTTVTQMSLSNPTM 627
             SH       + A SP +  SS       SP       SQ+ S  T   M++   T+
Sbjct: 10702 SHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTL 10757



 Score = 40.4 bits (93), Expect = 0.013
 Identities = 116/474 (24%), Positives = 183/474 (38%), Gaps = 80/474 (16%)

Query: 171   SQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTS 230
             SQV  S +D   S+   +  P P    T  ++A   G   Q+G    +  + +S     +
Sbjct: 11633 SQVTSSATDT--STAIPTLTPSPGEPETTASSATHPG--TQTGFTVPIRTVPSSEPDTMA 11688

Query: 231   RSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNG 290
                T    P++S  VSR+    SS   +       +A S RT      L   S       
Sbjct: 11689 SWVT--HPPQTSTPVSRTT---SSFSHSSPDATPVMATSPRTEASSAVLTTISPG----- 11738

Query: 291   AGNRSSTSSIDSNISSKSAGLPV----PKLREPSKTALGSSLPGLVNQTDKEKGISSDNE 346
                   TS I S+ ++ S  +P     P +  P  TAL S+ P    +T K    S+   
Sbjct: 11739 -APEMVTSQITSSGAATSTTVPTLTHSPGM--PETTALLSTHPR--TETSKTFPASTVFP 11793

Query: 347   SVASCN-SVKVNPAAQPVSS-PAQTS------LQPGAKYPDVASPTLRRLFGGKPTKQVP 398
              V+    S+ + P A+  ++ P QT+      L  G    D+ SPT      G   K  P
Sbjct: 11794 QVSETTASLTIRPGAETSTALPTQTTSSLFTLLVTGTSRVDL-SPTASP---GVSAKTAP 11849

Query: 399   IATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPS 458
             ++T    + S +I  P +T++  G L++   +G+L++ SS+   +  + L  SP  S  S
Sbjct: 11850 LSTHPGTETSTMI--PTSTLSL-GLLET---TGLLATSSSAETSTSTLTLTVSPAVSGLS 11903

Query: 459   SAH---SAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSS 515
             SA      P    +W T  S S  V+  G    S +   T+   I   + +    SH   
Sbjct: 11904 SASITTDKPQTVTSWNTETSPS--VTSVGPPEFSRTVTGTTMTLIPSEMPTPPKTSHGEG 11961

Query: 516   TGLIASSKDDSLTPFVRTNSVKTT---LSESDPHLDRNTL---PKKGLRYTPTS------ 563
                       S T  +RT  V+ T    + S P + + T       G  +TP +      
Sbjct: 11962 V---------SPTTILRTTMVEATNLATTGSSPTVAKTTTTFNTLAGSLFTPLTTPGMST 12012

Query: 564   ------QLRTQEDAKEWLRSHSAGGLQ------DTAANSPFSSGSSVTS-PSGT 604
                     RT  + + W+ + S+   +       T   S FS G S +S PS T
Sbjct: 12013 LASESVTSRTSYNHRSWISTTSSYNRRYWTPATSTPVTSTFSPGISTSSIPSST 12066



 Score = 38.9 bits (89), Expect = 0.038
 Identities = 100/453 (22%), Positives = 162/453 (35%), Gaps = 67/453 (14%)

Query: 295  SSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSV 354
            +++S   ++++  + G+PV      SKTA GSS PG          +SS     +S  S 
Sbjct: 631  TASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPG--GTKPSYTMVSSVIPETSSLQSS 688

Query: 355  KVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENM---KNSVVI 411
                      +P  T     +  PD A  T       K +  +P+ ++ ++   K S   
Sbjct: 689  AFREGTSLGLTPLNTRHPFSSPEPDSAGHT-------KISTSIPLLSSASVLEDKVSATS 741

Query: 412  SNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWG 471
            +  H   T      +P  S   +  SS+ L S    +  S  A+SP    +A S  LT  
Sbjct: 742  TFSHHKATSSITTGTPEIS-TKTKPSSAVLSS----MTLSNAATSPERVRNATS-PLTHP 795

Query: 472  TNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFV 531
            + +   +A         SV +L TS E+ D          H + T    SS+  S     
Sbjct: 796  SPSGEETA--------GSVLTLSTSAETTD------SPNIHPTGTLTSESSESPSTLSLP 841

Query: 532  RTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSP 591
              + VKTT S S                TP++ L T                ++T   S 
Sbjct: 842  SVSGVKTTFSSS----------------TPSTHLFTSG--------------EETEETSN 871

Query: 592  FSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNS 651
             S     TS S  R   +  + PT V     + PT     S S+   +    + +   NS
Sbjct: 872  PSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNS 931

Query: 652  SMS----LDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRE 707
            + S    +   + T + S + RD F +      +    TS  + T      + +      
Sbjct: 932  TGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATS 991

Query: 708  LDASQEKVSALTTQLTANAHLVAAFEQSLGNMT 740
            L A+   VS  T+  T++    +  E S   +T
Sbjct: 992  LSAT-VMVSKFTSPATSSMEATSIREPSTTILT 1023



 Score = 37.7 bits (86), Expect = 0.084
 Identities = 130/648 (20%), Positives = 230/648 (35%), Gaps = 111/648 (17%)

Query: 97   NPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTD 156
            +PS VS  S +S      PV +   S     T  +G T P    S+P   L +P   +  
Sbjct: 5641 SPSPVSSTSPESIPSSPLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPN-LSSPTQERLT 5699

Query: 157  DAKVSEKGRLSPKASQVKRSPSDAGRS-SGDESKKPLPSSSRTPTANAN---SFGFKKQS 212
              K +        +     + ++ G S SG ES+  +P+ S T  A +    +F     S
Sbjct: 5700 TYKDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSPMGITFAMGDTS 5759

Query: 213  GSAAGLAMI--------TASGV-------------TVTSRSATLGKIPKSSAL-VSRSAG 250
             S +  A          T+S +             TVT  S  L ++P ++   VSR+  
Sbjct: 5760 VSTSTPAFFETRIQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEV 5819

Query: 251  RKSSMDGAQNQDDGYLA--LSSRTNLQYRSLPRPSKSNSR---NGAG------------N 293
              SS       D   ++  +S+ T  +  + P  + S      N  G            +
Sbjct: 5820 ITSSRTTISGPDHSKMSPYISTETITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLD 5879

Query: 294  RSSTSSIDSNISSKSAGLP-------------------VPKLREPSKTALGSSLPGLVNQ 334
             SST+S +   S  +   P                    P + E S  +    LP + + 
Sbjct: 5880 TSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSH 5939

Query: 335  TDKEKGISSDNESVA-------------SCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVA 381
            +     +S  + + A             + + +  +      S P+ +S   G      A
Sbjct: 5940 SSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFS-GEILTSEA 5998

Query: 382  SPTLRRLFGGKPTKQVPIATAENMK---NSVVISNPHATMTQQGNLDSPSGSGVLSSGSS 438
            S     +   + T +  + T  +M    +SV I +  +  T      S     ++S+ + 
Sbjct: 5999 STNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTP 6058

Query: 439  SPLYSKNVDLNQ-SPLASSPSSAHSA-------PSNSLTWGTNASSSSAVSKDGLGFQSV 490
                +KNVD +  SPL        +A        SN++    +  +++ VS+  + +   
Sbjct: 6059 GSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDP 6118

Query: 491  SSLHTSCESIDI-SLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDR 549
            + +  S +S     +S     SH++S  L  S+     T      S  T+L +    LD 
Sbjct: 6119 TFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQ--TGPSGVTSLGQLT--LDT 6174

Query: 550  NTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSS-----------V 598
            +T+         T   RTQ+       S     L D    SPFS+  +            
Sbjct: 6175 STIATSA----GTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVT 6230

Query: 599  TSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDS 646
            TSPS       + ++ + V+  S+  PT+ +   +++ D   +P T S
Sbjct: 6231 TSPSPVTSTLQEHSTSSLVSVTSVPTPTLAK---ITDMDTNLEPVTRS 6275



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 131/700 (18%), Positives = 259/700 (37%), Gaps = 85/700 (12%)

Query: 353  SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412
            S+ V+     +   +  SL PG +   ++              +VP  T         +S
Sbjct: 6931 SMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAE------VS 6984

Query: 413  NPHATMTQQGNLDSPSGSGVLSSGS--------SSPLYSKNVDLNQSPLASSPSSAHSAP 464
                T + + ++  PS S VL   S        +SP  +++ ++   P  + PS   S  
Sbjct: 6985 RTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMT-IPTQTGPSG--STS 7041

Query: 465  SNSLTWGTNASSSSAVSKDGL--------------------GFQSVSSLH--TSCESIDI 502
             ++LT  T+ + S A +   L                     +QS  SL   +S  S+  
Sbjct: 7042 QDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLS 7101

Query: 503  SLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTT-LSESDPHLDRNTLPKKGLRYTP 561
              ++   P  +S+  +  SS    +T  + ++ V TT +  + P L  ++ PK  L +T 
Sbjct: 7102 LPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPK--LSHTS 7159

Query: 562  TSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQ-- 619
              +L T +D       H +     +    P SSG    S +      S+  SP  +T   
Sbjct: 7160 DERLTTGKDTTNTEAVHPSTNTAASNVEIP-SSGHESPSSALADSETSKATSPMFITSTQ 7218

Query: 620  ----MSLSNPTMLRT-----HSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRD 670
                +++S P  L T      S+S+   +      S   +S++        +S   +   
Sbjct: 7219 EDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEI 7278

Query: 671  GFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRE---LDASQEKVSALTTQLTANAH 727
               EV  SS + +S ++     PE     +I K        ++S+  +   T+   + + 
Sbjct: 7279 SRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSE 7338

Query: 728  LVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPEL 787
                 + S     +   S TMT     SE+  L             ++ A  G +  P  
Sbjct: 7339 STFTLDTSTTPSLVITHS-TMTQRLPHSEITTL------------VSRGA--GDVPRPSS 7383

Query: 788  NCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWLRSSFKQA 847
                  +  S+ L +    S   VSS   A+SHSS  S     +  + +   +  +   A
Sbjct: 7384 LPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDA--SA 7441

Query: 848  FGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHS-----NSLISECM 902
              +  SP S SS S +E +  S + +  +  H  S  +   +  S S     +S++ +  
Sbjct: 7442 EPETSSPPSLSSTS-VEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSE 7500

Query: 903  DSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLK 962
             ++A + M   + + D  +        ALS+  ++    E  + + + + +     +   
Sbjct: 7501 TTKATSAMGTISIMGDTSVSTL---TPALSNTRKIQS--EPASSLTTRLRETSTSEETSL 7555

Query: 963  SESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSL 1002
            +    +  S+  +  +   S  +++  S+ S++  E +++
Sbjct: 7556 ATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTM 7595



 Score = 35.8 bits (81), Expect = 0.32
 Identities = 123/633 (19%), Positives = 226/633 (35%), Gaps = 80/633 (12%)

Query: 131   VGITMPRTKPSAPAG--ALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDES 188
             V  T+P++ PS+     +L TPG  KT D        LSP  S        A   + D  
Sbjct: 10035 VSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLSPNLSGTSVEILAASEVTTDTE 10094

Query: 189   KKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRS 248
             K    SS         S G +  S         + S  +  S++      P S A  S S
Sbjct: 10095 KIHPSSSMAVTNVGTTSSGHELYS---------SVSIHSEPSKATYPVGTPSSMAETSIS 10145

Query: 249   AGRKSSMDGAQNQDDGYLALSS---RTNLQY-RSLPRPSKSNSRNGAGNRSSTSSIDSNI 304
                 ++ +    + + +  L+S   +TN+    S   P+ + S  G+ +   +S  D   
Sbjct: 10146 TSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSKTDFTS 10205

Query: 305   SSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEK-GISSDNESVASCNSVKVNPAAQPV 363
             S+K++    P   + ++  +    P   + +  E  GI+S  ES  + +  +        
Sbjct: 10206 SAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFTMSVTESTHHLSTD 10265

Query: 364   SSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGN 423
               P+  ++  G        P+L        T  VP A +         S    + T+ G 
Sbjct: 10266 LLPSAETISTG-----TVMPSLSEAMTSFATTGVPRAISG--------SGSPFSRTESGP 10312

Query: 424   LDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKD 483
              D+   +   S  SS+P+   +     +  ++ P+      S++  +  + S  +  S  
Sbjct: 10313 GDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTT 10372

Query: 484   GLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDS-----LTPFVRTNSVKT 538
                   VS+L TS +           P   SS+ ++ +   +S     +T   +  S+ T
Sbjct: 10373 EGRLVMVSTLDTSSQ-----------PGRTSSSPILDTRMTESVELGTVTSAYQVPSLST 10421

Query: 539   TLSESD------------------------PHLDRNTLPKKGLRYTPTSQLRTQEDAKEW 574
              L+ +D                        P    +    KGL    T ++ T   A + 
Sbjct: 10422 RLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALK- 10480

Query: 575   LRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTML-----R 629
                 +   L+ T+  +  +S  + T  + T  N S   + T  T+M ++ P +       
Sbjct: 10481 ---TTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPET 10537

Query: 630   THSLSNADGQYDPYTDSRFRNSSMSLDEKSRT--MSRSGSFRDGFEEVHGSSLSLVSSTS 687
             T SL+ + G        R   S  + + ++    +SRSG+ R    +    S S   +T+
Sbjct: 10538 TSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTTA 10597

Query: 688   SVYSTPEEKCQSEIRKLRRELDASQEKVSALTT 720
             S    P E   +  +       +  + VS+  T
Sbjct: 10598 SWVIHPAETIPTVSKTTPNFFHSELDTVSSTAT 10630



 Score = 34.3 bits (77), Expect = 0.93
 Identities = 91/463 (19%), Positives = 166/463 (35%), Gaps = 57/463 (12%)

Query: 212  SGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSR 271
            S   A  + I A   +    S  +    +  A+VS S         A+ + + +L +  R
Sbjct: 3959 SSEHASHSTIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELR 4018

Query: 272  TNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGL 331
                Y      ++++  +  G+ + T    + I+S             SK    S L   
Sbjct: 4019 DVSPYMDTSSTTQTSIISSPGSTAITKGPRTEITS-------------SKRISSSFLAQS 4065

Query: 332  VNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGG 391
            +  +D      S +E++   ++      +  +    QTS  PGA    +++PTL      
Sbjct: 4066 MRSSD------SPSEAITRLSNFPAMTESGGMILAMQTS-PPGAT--SLSAPTLDTSATA 4116

Query: 392  KPTKQVPIATAENMKNSVVISNPHATMTQQGNLDS--PSGSGVLSSGSSSPLYSKNVDLN 449
              T   P+AT +    S        T+  +G  D+  PS   V  + SSS L        
Sbjct: 4117 SWTG-TPLATTQRFTYS-----EKTTLFSKGPEDTSQPSPPSVEETSSSSSLV------- 4163

Query: 450  QSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSG-G 508
                   P  A ++PSN L      S SS      +     S L  + +   ISL  G  
Sbjct: 4164 -------PIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTS 4216

Query: 509  VPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTP-TSQLRT 567
            +P + SST        ++L+ +  +   K     +D  +    +      Y+P     + 
Sbjct: 4217 LPPNLSSTA------GEALSTYEASRDTKAIHHSADTAV--TNMEATSSEYSPIPGHTKP 4268

Query: 568  QEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTM 627
             +     + SH  G +  T++ S F S  +    + +  N       T+    S +  + 
Sbjct: 4269 SKATSPLVTSHIMGDI--TSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSATETST 4326

Query: 628  LRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRD 670
            + TH  S     +   T + F +S  S+    + ++ + +F D
Sbjct: 4327 VITHVSSGDATTHVTKTQATF-SSGTSISSPHQFITSTNTFTD 4368


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 57.8 bits (138), Expect = 8e-08
 Identities = 158/752 (21%), Positives = 276/752 (36%), Gaps = 96/752 (12%)

Query: 13   SSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHS---QVERNSL 69
            S++  S   DT   L  DD  TS  + +   T +S+       T A   S   Q E  + 
Sbjct: 1524 STTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTF 1583

Query: 70   --W-SGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSD-----------ESDKSTSGKKNP 115
              W S  D   S  G+ +   +E  + +   PS                S++ST+   +P
Sbjct: 1584 QSWPSSSDTTPSPPGTTAA-PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 1642

Query: 116  VISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRL---SPKASQ 172
              + T  +       V +  P T P +      T   G T  A +SEK      SP++  
Sbjct: 1643 GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPD 1702

Query: 173  VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSF-GFKKQSG----SAAGLAMITASGVT 227
               SP  A  +S   S++   S SR  + +  +F G     G    S A  +   ++  T
Sbjct: 1703 TTLSP--ASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTT 1760

Query: 228  VTSRSATLGKI-PKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSN 286
            ++  S T   + P+S+   S     ++++        G L  S+     + S   P  + 
Sbjct: 1761 LSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPV---HSSTGSPHTTL 1817

Query: 287  SRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNE 346
            S  G+  R   S+   +  S    +P P     +   L ++  G  + T      +S   
Sbjct: 1818 SPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTT 1877

Query: 347  SVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMK 406
               S  S  V+      SSP  T+  P                   P +       E  +
Sbjct: 1878 LGRSEESTTVH------SSPVATATTP------------------SPARSTTSGLVE--E 1911

Query: 407  NSVVISNPHATMTQ---QGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSA 463
            ++   S+P +T T    + +  S       +S SS+     +     S L   P+S HS+
Sbjct: 1912 STAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSS 1971

Query: 464  PSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSK 523
            P ++ T  T+   SS  S  G   +S +S H+S ++    +    +P+ ++++ L+    
Sbjct: 1972 PGSTAT--THFPDSSTTS--GRSEESTAS-HSSQDATGTIV----LPARSTTSVLLG--- 2019

Query: 524  DDSLTPFVRTNSVKTTL---SESDPHLDRNTLPKKGLRYTPTSQLRTQED-----AKEWL 575
             +S T  + + S++TT    S + P L   +        +P + L          ++E  
Sbjct: 2020 -ESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEEST 2078

Query: 576  RSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSN 635
             SHS  G   T A        S T+P  +R + +  +SP +      ++ T+L   + ++
Sbjct: 2079 TSHSRPGSTHTTA-----FPDSTTTPGLSRHSTTSHSSPGS------TDTTLLPASTTTS 2127

Query: 636  ADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLV---SSTSSVYST 692
               Q    + S   ++  +L   S T    G     F    GS+ + +   S+TSS    
Sbjct: 2128 GPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 2187

Query: 693  PEEKCQSEIRKLRRELDASQEKVSALTTQLTA 724
               +  S     R  L  +      L  + TA
Sbjct: 2188 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTA 2219



 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 145/705 (20%), Positives = 260/705 (36%), Gaps = 91/705 (12%)

Query: 13   SSSVSSGISDT-IDNLSTDDINTSSSISSYANTPASSRKNLD---------VQTDAEKHS 62
            +S  SSG +DT +   ST  ++     +++ ++P S+   L          V+     HS
Sbjct: 3692 TSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHS 3751

Query: 63   QV--ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRN--PSDVSDESDKSTSGKKNPVIS 118
                 R +L           G  +  +  P S       PS  +   ++ST+  ++P  +
Sbjct: 3752 STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 3811

Query: 119  QTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGK--TDDAKVSEKGRLSPKASQVKRS 176
             T  +    T            S+P  +  TP +    T     S   R+SP ++++   
Sbjct: 3812 PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTL 3871

Query: 177  PSDAGRSSGDESKKPLPSSSRTPT-----ANANSFGFKKQSGSAAGLAMITASGVTVTSR 231
            P         E+     SS R+PT     A+  S G  ++S ++      T S V+  S 
Sbjct: 3872 PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS- 3930

Query: 232  SATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGA 291
            + T G   +S+ + S S G         + +      S+ T+++ R  P    S   +  
Sbjct: 3931 TTTPGLSEESTTVYSSSPG---------STETTVFPRSTTTSVR-REEPTTFHSRPASTH 3980

Query: 292  GNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASC 351
                +  S  S ++ +S   P      P+ T  G  LP  +   D  +  S+   S +  
Sbjct: 3981 TTLFTEDSTTSGLTEESTAFP----GSPASTQTG--LPATLTTADLGEE-STTFPSSSGS 4033

Query: 352  NSVKVNPAAQPVS-------------SPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVP 398
               K++PA    S             S  +T+  PG+      S      +    +    
Sbjct: 4034 TGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 4093

Query: 399  IATAE------NMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSP 452
            ++ A       + ++S   S P +T T     DS + SG+    ++S     + +   SP
Sbjct: 4094 LSPATTTSSGVSEESSTSHSQPGSTHT-TAFPDSTTTSGLSQEPTTSHSSQGSTEATLSP 4152

Query: 453  LASSPSSA-------HSAPSNSLT--WGTNASSSSAVSKDGLGFQSVSSLHTSCESIDIS 503
             +++ SS        HS+P ++ T     +  +S  V        S  SLHT+      S
Sbjct: 4153 GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTL--TPAS 4210

Query: 504  LSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTS 563
             +S G+   +++     SS D + +P   T +V   +S +  H   ++ P      + T+
Sbjct: 4211 STSTGLQEESTTFQSWPSSSDTTPSP-PSTTAVPVEVS-TTYHSRPSSTPTTHFSASSTT 4268

Query: 564  QLRTQEDAKEWLRSHSAGGLQDTA---------------ANSPFSSGSSVTSPSGTRFNF 608
              R++E        HS+ G   TA                 SP SSGS+ T+        
Sbjct: 4269 LGRSEEST----TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT 4324

Query: 609  SQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSM 653
            + L+  +T    S  +P    + + + + G  +  T S  R  SM
Sbjct: 4325 AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSM 4369



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 195/947 (20%), Positives = 321/947 (33%), Gaps = 126/947 (13%)

Query: 13   SSSVSSGISDT-IDNLSTDDINTSSSISSYANTPASSRKNLD---------VQTDAEKHS 62
            +S  SSG +DT +   ST  ++     +++ + P S+   L          V+     HS
Sbjct: 1052 TSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHS 1111

Query: 63   QV--ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRN--PSDVSDESDKSTSGKKNPVIS 118
                 R +L           G  +  +  P S       PS  +   ++ST+  ++P  +
Sbjct: 1112 STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 1171

Query: 119  QTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGK--TDDAKVSEKGRLSPKASQVKRS 176
             T  +    T            S+P  +  TP +    T     S   R+SP ++++   
Sbjct: 1172 PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTL 1231

Query: 177  PSDAGRSSGDESKKPLPSSSRTPT-----ANANSFGFKKQSGSAAGLAMITASGVTVTSR 231
            P         E+     SS R+PT     A+  S G  ++S ++      T S V+  S 
Sbjct: 1232 PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS- 1290

Query: 232  SATLGKIPKSSALVSRSAG----------RKSSMDG----------AQNQDDGYLALSSR 271
            + T G   +S+ + S S G            +S+ G          A      +   S+ 
Sbjct: 1291 TTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTT 1350

Query: 272  TNLQYRSLPRP-SKSNSRNGAGNRSSTSSIDSN-----ISSKSAGLPVPKLREPSKTALG 325
            + L   S   P S ++++ G     +T+ +         SS S G  +   R  +   +G
Sbjct: 1351 SGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVG 1410

Query: 326  SSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVS-----SPAQTSLQPGAKYPDV 380
             S P  ++ +  E      + +  S +         P S     SPA T+    ++    
Sbjct: 1411 ESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE---- 1466

Query: 381  ASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLD---SPSGSGVLSSGS 437
             S T     G   T   P +T      S +   P  + + QG+ +   SP  +   S G 
Sbjct: 1467 ESSTSHSQPGSTHTTAFPDSTT----TSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQ 1522

Query: 438  SSPLYSKNV----------DLNQSPLASSPSSAHSAPSNSLTWGTNASSSSA-VSKDGLG 486
             S  +  +           D   S L  + +  HS+  +  T  T ASS+SA + ++   
Sbjct: 1523 QSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTT 1582

Query: 487  FQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPH 546
            FQS  S      S D + S  G  +          S+  S TP    ++  TTL  S+  
Sbjct: 1583 FQSWPS------SSDTTPSPPGTTAAPVEVSTTYHSRPSS-TPTTHFSASSTTLGRSEES 1635

Query: 547  LDRNTLP-KKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTR 605
               ++ P   G    PT                +   L      SP SSGS+ T+     
Sbjct: 1636 TTVHSSPGATGTALFPTRS--------------ATSVLVGEPTTSPISSGSTETT----- 1676

Query: 606  FNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRS 665
                  A P + T   LS  +     S  + D    P + +    S  S    SR  S  
Sbjct: 1677 ------ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTH 1730

Query: 666  GSFRDGFEEVHGSSLSLVSSTSSVYST-----PEEKCQSEIRKLRRELDAS--QEKVSAL 718
             +   G   + G S    +S SS  ST     P     S +        +S    + + L
Sbjct: 1731 TTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLL 1790

Query: 719  TTQLTANAHLVAA--FEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQA 776
                TA+  L A+     S G+    L     T  Q +S       T +          A
Sbjct: 1791 PDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGES------TTFQSWPSSKDTMPA 1844

Query: 777  AINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKR 836
                     EL+   +G+  S         S+    S  S T HSS  +   + S  +  
Sbjct: 1845 PPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARST 1904

Query: 837  KNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGST 883
             + L    +++     SP S  +    E  T S      +  H+ +T
Sbjct: 1905 TSGL---VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTT 1948



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 141/677 (20%), Positives = 245/677 (36%), Gaps = 81/677 (11%)

Query: 13   SSSVSSGISDT-IDNLSTDDINTSSSISSYANTPASSRKNLD---------VQTDAEKHS 62
            +S  S G +DT +   ST  ++     +++ ++P S+   L          V+     HS
Sbjct: 2609 TSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHS 2668

Query: 63   QV--ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRN--PSDVSDESDKSTSGKKNPVIS 118
                 R +L           G  +  +  P S       PS  +   ++ST+  ++P  +
Sbjct: 2669 STGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 2728

Query: 119  QTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGK--TDDAKVSEKGRLSPKASQVKRS 176
             T  +    T            S+P  +  TP +    T     S   R+SP ++++   
Sbjct: 2729 PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTL 2788

Query: 177  PSDAGRSSGDESKKPLPSSSRTPT-----ANANSFGFKKQSGSAAGLAMITASGVTVTSR 231
            P         E+     SS R+PT     A+  S G  ++S ++      T S V+  S 
Sbjct: 2789 PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS- 2847

Query: 232  SATLGKIPKSSALVSRSAGR-------KSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSK 284
            + T G   +S+ + S S G        +S+    + ++       SR    + +L     
Sbjct: 2848 TTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEP--TTFHSRPASTHTTLFTEDS 2905

Query: 285  SNSRNGAGNRSSTSSIDSNISSKSAGLP----VPKLREPSKT------ALGSSLPGLVNQ 334
            + S    G    +++   + +S   GLP       L E S T      + G++L    + 
Sbjct: 2906 TTS----GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARST 2961

Query: 335  TDKEKGISSDNESVASCNSVKVNPAA--QPVSSPAQTSLQPGAKYPDVA-SPTLRRLFG- 390
            T    G S+ +    S       P +   P  S   T+     + PD   SP      G 
Sbjct: 2962 TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 3021

Query: 391  --------GKPTKQVPIATAENMKNSVVISNPHATMTQQGNLD---SPSGSGVLSSGSSS 439
                     +P      A  ++   S +   P A+ + QG+ +   SP  +   S G  S
Sbjct: 3022 SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQS 3081

Query: 440  PLYSKNV----------DLNQSPLASSPSSAHSAPSNSLTWGTNASSSSA-VSKDGLGFQ 488
              +  +           D   S L  + +  HS+  +  T  T ASS+SA + ++   FQ
Sbjct: 3082 TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ 3141

Query: 489  SVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPHLD 548
            S  S      S D + S  G  +          S+  S TP    ++  TTL  S+    
Sbjct: 3142 SWPS------SSDTTPSPPGTTAAPVEVSTTYHSRPSS-TPTTHFSASSTTLGRSEESTT 3194

Query: 549  RNTLP-KKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFN 607
             ++ P   G    PT    +    +      S+G  + TA   P S+ ++  S   T F 
Sbjct: 3195 VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTAL--PGSTTTAGLSEKSTTFY 3252

Query: 608  FSQLASPTTVTQMSLSN 624
             S  +  TT++  S ++
Sbjct: 3253 SSPRSPDTTLSPASTTS 3269



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 189/926 (20%), Positives = 326/926 (35%), Gaps = 139/926 (15%)

Query: 13   SSSVSSGISDT-IDNLSTDDINTSSSISSYANTPASSRKNLD---------VQTDAEKHS 62
            +S  S G +DT +   ST  ++     +++ ++P S+   L          V+     HS
Sbjct: 2135 TSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHS 2194

Query: 63   QV--ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRN--PSDVSDESDKSTSGKKNPVIS 118
                 R +L           G  +  +  P S       PS  +   ++ST+  ++P  +
Sbjct: 2195 STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 2254

Query: 119  QTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGK--TDDAKVSEKGRLSPKASQVKRS 176
             T  +    T            S+P  +  TP +    T     S   R+SP ++++   
Sbjct: 2255 PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTL 2314

Query: 177  PSDAGRSSGDESKKPLPSSSRTPT-----ANANSFGFKKQSGSAAGLAMITASGVTVTSR 231
            P         E+     SS R+PT     A+  S G  ++S ++      T S V+  S 
Sbjct: 2315 PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS- 2373

Query: 232  SATLGKIPKSSALVSRSAGR----------KSSMDG----------AQNQDDGYLALSSR 271
            + T G   +S+ + S S G            +S+ G          A      +   S+ 
Sbjct: 2374 TTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTT 2433

Query: 272  TNLQYRSLPRP-SKSNSRNGAGNRSSTSSIDSN-----ISSKSAGLPVPKLREPSKTALG 325
            + L   S   P S ++++ G     +T+ +         SS S G  +   R  +   +G
Sbjct: 2434 SGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVG 2493

Query: 326  SSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVS-----SPAQTS---------- 370
             S P  ++ +  E      + +  S +         P S     SPA T+          
Sbjct: 2494 ESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST 2553

Query: 371  --LQPGA----KYPD-VASPTLRRLF-------GGKPTKQVPIAT---AENMKNSVVISN 413
               QPG+     +PD   +P L R         G   T  +P +T     + +++   S+
Sbjct: 2554 SHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 2613

Query: 414  PHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSA--PSNSLTWG 471
            P +T T      SP  +  LS G  S  +            SSP S H+   P ++ + G
Sbjct: 2614 PGSTDTAL----SPGSTTALSFGQESTTFH-----------SSPGSTHTTLFPDSTTSSG 2658

Query: 472  -----TNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDS 526
                 T   SS+   +  L   S +S     ES           +  S      +  ++S
Sbjct: 2659 IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEES 2718

Query: 527  LTPFVRTNSVKTT----LSESDPHLDRNTL---PKKGLRYTPTSQLRTQEDAKEWLRSHS 579
             T      S  TT     S +  H +++T+          TP+S   T     E   S  
Sbjct: 2719 TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRI 2778

Query: 580  AGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQ 639
            + G  +     P S+ +   S + T F  S  +  TT++  S+++  +    + S +   
Sbjct: 2779 SPGSTE-ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 2837

Query: 640  YDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLV---SSTSSVYSTPEEK 696
                T S    ++  L E+S T+  S           GS+ + V   S+T+SV       
Sbjct: 2838 STHSTVSPASTTTPGLSEESTTVYSSSP---------GSTETTVFPRSTTTSVRGEEPTT 2888

Query: 697  CQSEIRKLRRELDASQEKVSALTTQLTA----NAHLVAAFEQSLGNMTIRLQSLTM--TA 750
              S        L       S LT + TA     A        +L    +  +S T   ++
Sbjct: 2889 FHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS 2948

Query: 751  EQKDSELNELRKTIELLKKQNAAAQ--------AAINGVINTPELNCKGN---GTAQSAD 799
                + L+  R T   L  ++  ++          + G   TP L+ K      + +S D
Sbjct: 2949 GSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 3008

Query: 800  LRIRRQHSSDSVSSINSATSHSSVGS 825
              +    ++ S  S  S+TSHS  GS
Sbjct: 3009 ATLSPATTTSSGVSEESSTSHSQPGS 3034



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 105/458 (22%), Positives = 171/458 (37%), Gaps = 41/458 (8%)

Query: 183  SSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTV--TSRSATLGKIPK 240
            SSG      LP S+ TP  +  S  F   S S+      +AS  T+  +  S T+   P 
Sbjct: 4667 SSGSMETTALPGSTTTPGLSEKSTTF-HSSPSSTPTTHFSASSTTLGRSEESTTVHSSPV 4725

Query: 241  SSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSR---NGAGNRSST 297
            ++A     A  +S+  G   +   Y   SS  + Q    P  S ++ R   +   + S+T
Sbjct: 4726 ATATTPSPA--RSTTSGLVEESTAY--HSSPGSTQTMHFPESSTASGRSEESRTSHSSTT 4781

Query: 298  SSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVN 357
             +I S  S+ SA +  P     S  ++ ++     + T      S+ + S    N +   
Sbjct: 4782 HTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPL 4841

Query: 358  PAAQPVSSPAQTS----LQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISN 413
            PA    S     S    + PG+    +AS         K T    I  + +      +S 
Sbjct: 4842 PAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKST----ILYSSSRSPDQTLS- 4896

Query: 414  PHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSN---SLTW 470
              A+MT       P  + + S   S+   +       S L+   ++ HS P +   +L+ 
Sbjct: 4897 -PASMTSSSISGEP--TSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSP 4953

Query: 471  GTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPS-HNSSTGLIASSKDDSLTP 529
            G+  +SS A        Q  S+L T      +S +S  VP     ST   +S      T 
Sbjct: 4954 GSITTSSFAQEFTTPHSQPGSALST------VSPASTTVPGLSEESTTFYSSPGSTETTA 5007

Query: 530  FVRTNSVKTTLSESDPHLDRNTLPKKGLRYTP-TSQLRTQEDAKEWLRSHSAGGLQDTAA 588
            F  +N++     +S P  D       G  +T   + L T +  +E    HS+    D   
Sbjct: 5008 FSHSNTMSIHSQQSTPFPD-----SPGFTHTVLPATLTTTDIGQESTAFHSS---SDATG 5059

Query: 589  NSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPT 626
             +P  + S+ +   G    F    SPT  T    S+ T
Sbjct: 5060 TTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSST 5097



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 149/705 (21%), Positives = 252/705 (35%), Gaps = 81/705 (11%)

Query: 46  ASSRKNLDVQTDAEKHSQVERNSLWSGDDVKKSDGG-----------------SDSGIKM 88
           A+  +  + Q     HS     S  +G  V  S GG                 SD G+ +
Sbjct: 140 AAGAREKERQETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSV 199

Query: 89  -----EPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAP 143
                   +K   + S  S  S++ST     P  + T  +       V +  P+T P   
Sbjct: 200 TFITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITS 259

Query: 144 AGALKTPGTGKTDDAKVSEKGRL---SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPT 200
           A    T   G T  A +SEK      SP++    R+ S A  +S   S+K   S SR   
Sbjct: 260 ASMETTALPGSTTTAGLSEKSTTFYSSPRSPD--RTLSPARTTSSGVSEKSTTSHSRPGP 317

Query: 201 ANANSF-------GFKKQSGSAAGLAMITASGVTV-TSRSATLGKIPKSSALVSRSAGRK 252
            +  +F       G  ++S ++  +   T + ++  T+  ++LG  P+S+   S     K
Sbjct: 318 THTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLG--PESTTFHSSPGYTK 375

Query: 253 SSMDGAQNQDDGYLALS----SRTNLQYRSLPRPSKSNSRNGAGN--RSSTSSIDSNISS 306
           ++         G L  S    S T   + +L  PS S +  G     +S  SS D++ + 
Sbjct: 376 TTRLPDNTTTSGLLEASTPVHSSTGSPHTTL-SPSSSTTHEGEPTTFQSWPSSKDTSPAP 434

Query: 307 KSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSP 366
                   KL     ++  S+     + +    G S ++  V S      +P A   + P
Sbjct: 435 SGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHS------SPVATATTPP 488

Query: 367 AQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDS 426
              S   G      A     R  G   T   P ++  +  +    +   +T   + +  S
Sbjct: 489 PARSATSGHVEESTA---YHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPS 545

Query: 427 PSGSGVLSSGSSSPLYSKNVDLNQSPLASSPS----SAHSAPSNSLTWGTNASSSSAVSK 482
            + +   +S  SS   ++      S   S  S    ++HS+P    T    A S+ +V  
Sbjct: 546 TTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLV 605

Query: 483 DGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTN---SVKTT 539
                  +SS      ++  S +  G+   +++      S D +  P   T+   S ++T
Sbjct: 606 GDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEEST 665

Query: 540 LSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVT 599
            S S P     T           SQ        E   SHS+ G  DT   SP S+ +S  
Sbjct: 666 TSHSRPGSTHTTAFPGSTTMPGLSQ--------ESTASHSSPGPTDTTL-SPGSTTASSL 716

Query: 600 SPSGTRFNFSQLASPTTV------------TQMSLSNPTMLRTHSLSNADGQYDPYTDSR 647
            P  T F+    ++ TT+              M + + T     +LS A         + 
Sbjct: 717 GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTT 776

Query: 648 FRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYST 692
           F +   S D +    + + +F +     HGS  S+ ++  S  ST
Sbjct: 777 FHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARST 821



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 140/651 (21%), Positives = 232/651 (35%), Gaps = 77/651 (11%)

Query: 13   SSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTD--AEKHSQVERNSLW 70
            +S +SSG ++T    +     T++ +S  + T  SS ++ D      +   S V   S  
Sbjct: 3222 TSPISSGSTETT---ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTT 3278

Query: 71   SGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQ 130
            S      +   +  G    PG       S  S  S  +T    +   S  G       + 
Sbjct: 3279 SHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSG 3338

Query: 131  VGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKK 190
             G T     P     +     +     +  S    LSP  S  ++  S   +S  +    
Sbjct: 3339 PGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPN---- 3394

Query: 191  PLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAG 250
               S   TP     +  F + S ++ G    T +    ++ S TLG+  +S+ + S    
Sbjct: 3395 ---SKDTTPAPPTTTSAFVELSTTSHGSPSSTPT-THFSASSTTLGRSEESTTVHSSPVA 3450

Query: 251  RKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSK------SNSRNGAGNRSSTSSIDSNI 304
              ++   A++   G +  S+     Y S P  ++      S++ +G G  S+TS   +  
Sbjct: 3451 TATTPSPARSTTSGLVEESTT----YHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTH 3506

Query: 305  SSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVS 364
            +  SA      L E   T+  SS PG    T      ++   S  S  S     A   + 
Sbjct: 3507 TISSAPSTTSALVE-EPTSYHSS-PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV 3564

Query: 365  SPAQ--TSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAE---NMKNSVVISNPHATMT 419
             PA+  TS+  G       S       G   T  +P +T     + K++   S+P +  T
Sbjct: 3565 LPARSTTSVLLGESTTSPISS------GSMETTALPGSTTTPGLSEKSTTFHSSPRSPAT 3618

Query: 420  QQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPS--SAHSAPSNSLTWGTNASSS 477
                  + S SGV    ++S     +      P +++    S HS  S+S    T+ +  
Sbjct: 3619 TLSPASTTS-SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL 3677

Query: 478  SAVSKDGLGFQSVSSLHTSCESIDISLSSGGV------------------------PSHN 513
             A +      Q  ++ H+S  S D +LS G                          P   
Sbjct: 3678 PASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST 3737

Query: 514  SSTGLI-ASSKDDSLTPFVRTNSVKTTL---SESDPHLDRNTLP----KKGLRYTPTSQL 565
            +S+G++ AS++  S      T S +TTL   S + P L   +            TP+   
Sbjct: 3738 TSSGIVEASTRVHS-----STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPS 3792

Query: 566  RTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTT 616
                  +E    H + G   T  + P SS +S  S   T F+ S  AS TT
Sbjct: 3793 TATAPVEESTTYHRSPGSTPT-THFPASSTTSGHSEKSTIFHSSPDASGTT 3842



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 126/647 (19%), Positives = 224/647 (34%), Gaps = 96/647 (14%)

Query: 96   RNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKT 155
            R+ S +S  S++S +   +P    T     G T  V +      P +      T   G T
Sbjct: 568  RDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST 627

Query: 156  DDAKVSEKGRL------SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFK 209
                +SEK         SP  + +  S + +G S    +    P S+ T     ++    
Sbjct: 628  TKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 687

Query: 210  KQSGSAAGLAMITASGVTVTSRSATLGKI-PKSSALVSRSAGRKSSMDGAQNQDDGYLAL 268
                S A  +    +  T++  S T   + P+ +   SR    ++++        G L  
Sbjct: 688  LSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEA 747

Query: 269  SSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLR-----EPSKTA 323
            S   +   RS   P  + S  G+  R   S+   +  S     P P        EPS T+
Sbjct: 748  SMPVHSSTRS---PHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTS 804

Query: 324  LGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASP 383
             GS              I + + S  S  S  V  +    SSP  T       +P+    
Sbjct: 805  HGSP-----------SSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM---HFPE---- 846

Query: 384  TLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYS 443
                                             T + +G   + S S    + SS+P  +
Sbjct: 847  -------------------------------SDTTSGRGEESTTSHSSTTHTISSAPSTT 875

Query: 444  KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDIS 503
                   S L   P+S HS+P ++ T  T+   SS  S  G   +S +S H+S ++    
Sbjct: 876  -------SALVEEPTSYHSSPGSTAT--THFPDSSTTS--GRSEESTAS-HSSQDATGTI 923

Query: 504  LSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTL---SESDPHLDRNTLPKKGLRYT 560
            +    +P+ ++++ L+     +S T  + + S++TT    S + P L   +        +
Sbjct: 924  V----LPARSTTSVLLG----ESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRS 975

Query: 561  PTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQM 620
            P + L         +   S        +    +   S T+P  +R + +  +SP +    
Sbjct: 976  PATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS---- 1031

Query: 621  SLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSL 680
              ++ T+L   + ++   Q    + S   ++  +L   S T    G     F    GS+ 
Sbjct: 1032 --TDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTH 1089

Query: 681  SLV---SSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTA 724
            + +   S+TSS       +  S     R  L  +      L  + TA
Sbjct: 1090 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTA 1136



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 133/647 (20%), Positives = 231/647 (35%), Gaps = 71/647 (10%)

Query: 79   DGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQV------- 131
            D  + SG+  EP +      S  +  S  ST+       S T     G T          
Sbjct: 3042 DSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTI 3101

Query: 132  --GITMPRTKPSAPAGALKTPGT-GKTDDAKVSEKGRLS---PKASQVKRSPSDAGRSSG 185
              G+    T   +  G+L T  T   +  A + E+       P +S    SP     +  
Sbjct: 3102 TSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPV 3161

Query: 186  DESKKPLPSSSRTPT----ANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKIPKS 241
            + S       S TPT    A++ + G  ++S +       T + +  T  + ++     +
Sbjct: 3162 EVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPT 3221

Query: 242  SALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSID 301
            ++ +S  +   +++ G+         LS ++   Y S PR S   + + A   SS  S +
Sbjct: 3222 TSPISSGSTETTALPGSTTT----AGLSEKSTTFYSS-PR-SPDTTLSPASTTSSGVSEE 3275

Query: 302  SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQ 361
            S  S    G         S T     +PG+  +       S+ + S        ++P + 
Sbjct: 3276 STTSHSRPGSTHTTAFPGSTT-----MPGVSQE-------STASHSSPGSTDTTLSPGST 3323

Query: 362  PVSS--PAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMT 419
              SS  P  T+   G    +           G      P+ ++          +PH T++
Sbjct: 3324 TASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTG--------SPHTTLS 3375

Query: 420  QQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSA 479
              G+      S    S  +S   +       S      +++H +PS++ T   +ASS++ 
Sbjct: 3376 PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTT- 3434

Query: 480  VSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTT 539
                 LG    S   T+  S  ++ ++   P+ ++++GL+    ++S T      S +T 
Sbjct: 3435 -----LGRSEES---TTVHSSPVATATTPSPARSTTSGLV----EESTTYHSSPGSTQTM 3482

Query: 540  -LSESDPHLDR---NTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSG 595
               ESD    R   +T       +T +S   T     E   S+ +        + P SS 
Sbjct: 3483 HFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSST 3542

Query: 596  SSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSL 655
            +S  S   T  + SQ A+ T V     +   +L   + S         T      ++  L
Sbjct: 3543 TSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL 3602

Query: 656  DEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSEIR 702
             EKS T   S            ++LS  S+TSS  S  EE   S  R
Sbjct: 3603 SEKSTTFHSS-------PRSPATTLSPASTTSSGVS--EESTTSHSR 3640



 Score = 41.2 bits (95), Expect = 0.008
 Identities = 120/634 (18%), Positives = 225/634 (35%), Gaps = 53/634 (8%)

Query: 102  SDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVS 161
            S  S++S++    P  + T ++    T       P T  S+      T   G T  + + 
Sbjct: 4102 SGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLG 4161

Query: 162  EKGRL---SPKASQVKRSPSDAGRSSGDESKKPLPSSS---RTPTANANSFGFKKQSGSA 215
            ++      SP  ++    P D   S   E+  P  SS+    T    A+S     Q  S 
Sbjct: 4162 QQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEEST 4221

Query: 216  AGLAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDG----------- 264
               +  ++S  T +  S T   +  S+   SR +   ++   A +   G           
Sbjct: 4222 TFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS 4281

Query: 265  --------YLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGL-PVPK 315
                    +   S+ + L       P  S S        ST++  + +S KS      P+
Sbjct: 4282 PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT--AGLSEKSTTFYSSPR 4339

Query: 316  LREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPV----SSPAQT-- 369
              + + +   ++  G+  ++           + A  +S  +   +Q      SSP  T  
Sbjct: 4340 SPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDT 4399

Query: 370  SLQPGAKYPDVASP---TLRRLFGGKPTKQVPIATAEN--MKNSVVI----SNPHATMTQ 420
            +L PG+       P   T     G   T  +P  T  +  ++ S  +     +PH T++ 
Sbjct: 4400 TLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 4459

Query: 421  QGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAV 480
             G+      S    S  +S   +       S      +++H +PS++ T   +ASS++  
Sbjct: 4460 AGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTT-- 4517

Query: 481  SKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTL 540
                LG    S   T+  S  ++ ++   P+ ++++GL+  S     +P           
Sbjct: 4518 ----LGRSEES---TTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPES 4570

Query: 541  SESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTS 600
            + +    + +T       +T +S   T     E   S+ +        + P SS +S  S
Sbjct: 4571 NTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS 4630

Query: 601  PSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSR 660
               T  + SQ A+ T V     +   +L   + S         T      ++  L EKS 
Sbjct: 4631 EESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKST 4690

Query: 661  TMSRSGSFRDGFE-EVHGSSLSLVSSTSSVYSTP 693
            T   S S           ++L     +++V+S+P
Sbjct: 4691 TFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSP 4724



 Score = 40.4 bits (93), Expect = 0.013
 Identities = 137/668 (20%), Positives = 223/668 (33%), Gaps = 66/668 (9%)

Query: 13   SSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHSQVERNSLWSG 72
            +++ SSG+S+     S+   +   S  + A   +++   L  +  A   SQ    +  S 
Sbjct: 3014 ATTTSSGVSEE----SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSP 3069

Query: 73   DDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDE---SDKSTSG---KKNPVISQTGSWRRG 126
                 S  G  S       + +  +P D        D  TSG      P  S TGS    
Sbjct: 3070 GSTTASSLGQQS-------TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 3122

Query: 127  MT----AQVGITMPRTK-PSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQV-----KRS 176
            +T       G+    T   S P+ +  TP    T  A V        + S         S
Sbjct: 3123 LTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSAS 3182

Query: 177  PSDAGRSSGDESKKPLPSSSRT---PTANANSF--GFKKQSGSAAGLAMITA-SGVTVTS 230
             +  GRS    +    P ++ T   PT +A S   G    S  ++G    TA  G T T+
Sbjct: 3183 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTA 3242

Query: 231  ----RSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSN 286
                +S T    P+S       A   SS    ++        S+ T     S   P  S 
Sbjct: 3243 GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVS- 3301

Query: 287  SRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNE 346
             +    + SS  S D+ +S    G        P  T   S  PG    T     +  DN 
Sbjct: 3302 -QESTASHSSPGSTDTTLSP---GSTTASSLGPESTTFHSG-PGSTETT-----LLPDNT 3351

Query: 347  SVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMK 406
            + +        P      SP  T    G+      S T +     K T   P  T     
Sbjct: 3352 TASGLLEAST-PVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFV 3410

Query: 407  NSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAPSN 466
                      + T  G+  S   +   +S ++     ++  ++ SP+A++ + +   P+ 
Sbjct: 3411 E--------LSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS---PAR 3459

Query: 467  SLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDS 526
            S T G    S++  S  G    S  ++H                SH+S+T  I+S+   +
Sbjct: 3460 STTSGLVEESTTYHSSPG----STQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTT 3515

Query: 527  LTPFVRTNSVKTTL-SESDPHL-DRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQ 584
                    S  ++  S +  H  D +T   +    T +   +            +   L 
Sbjct: 3516 SALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLL 3575

Query: 585  DTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYT 644
              +  SP SSGS  T+          L+  +T    S  +P    + + + + G  +  T
Sbjct: 3576 GESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEEST 3635

Query: 645  DSRFRNSS 652
             S  R  S
Sbjct: 3636 TSHSRPGS 3643


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 124/560 (22%), Positives = 212/560 (37%), Gaps = 74/560 (13%)

Query: 13   SSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDAEKHS---QVERNSL 69
            S++  S   DT   L  DD  TS  + +   T +S+       T A   S   Q E  + 
Sbjct: 1011 STTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTF 1070

Query: 70   --W-SGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSD-----------ESDKSTSGKKNP 115
              W S  D   S  G+ +   +E  + +   PS                S++ST+   +P
Sbjct: 1071 QSWPSSSDTTPSPPGTTAA-PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP 1129

Query: 116  VISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRL---SPKASQ 172
              + T  +       V +  P T P +      T   G T  A +SEK      SP++  
Sbjct: 1130 GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPD 1189

Query: 173  VKRSPSDAGRSSGDESKKPLPSSSRTPTANANSF-GFKKQSG----SAAGLAMITASGVT 227
               SP  A  +S   S++   S SR  + +  +F G     G    S A  +   ++  T
Sbjct: 1190 TTLSP--ASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTT 1247

Query: 228  VTSRSATLGKI-PKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSN 286
            ++  S T   + P+S+   S     ++++        G L  S+     + S   P  + 
Sbjct: 1248 LSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPV---HSSTGSPHTTL 1304

Query: 287  SRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNE 346
            S  G+  R   S+   +  S    +P P     +   L ++  G  + T      +S   
Sbjct: 1305 SPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTT 1364

Query: 347  SVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMK 406
               S  S  V+      SSP  T+  P                   P +       E  +
Sbjct: 1365 LGRSEESTTVH------SSPVATATTP------------------SPARSTTSGLVE--E 1398

Query: 407  NSVVISNPHATMTQ---QGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSA 463
            ++   S+P +T T    + +  S       +S SS+     +     S L   P+S HS+
Sbjct: 1399 STAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSS 1458

Query: 464  PSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSK 523
            P +  T  T+   SS  S  G   +S +S H+S ++  I+     +P+H +++G IA   
Sbjct: 1459 PGSIAT--THFPESSTTS--GRSEESTAS-HSSPDTNGIT----PLPAHFTTSGRIA--- 1506

Query: 524  DDSLTPFVRTNSVKTTLSES 543
             +S T ++   S++TTL+ +
Sbjct: 1507 -ESTTFYISPGSMETTLAST 1525



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 127/598 (21%), Positives = 226/598 (37%), Gaps = 61/598 (10%)

Query: 96  RNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKT 155
           R+ S +S  S++S +   +P    T     G T  V +      P +      T   G T
Sbjct: 55  RDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST 114

Query: 156 DDAKVSEKGRL------SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFK 209
               +SEK         SP  + +  S + +G S    +    P S+ T     ++    
Sbjct: 115 TKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 174

Query: 210 KQSGSAAGLAMITASGVTVTSRSATLGKI-PKSSALVSRSAGRKSSMDGAQNQDDGYLAL 268
               S A  +    +  T++  S T   + P+ +   SR    ++++        G L  
Sbjct: 175 LSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEA 234

Query: 269 SSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLR-----EPSKTA 323
           S   +   RS   P  + S  G+  R   S+   +  S     P P        EPS T+
Sbjct: 235 SMPVHSSTRS---PHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTS 291

Query: 324 LG--SSLP-----------GLVNQTDKEKGISSDNESV----ASCNSVKVNPAAQPVSSP 366
            G  SS+P           GLV ++          +++    +   S +   +    SS 
Sbjct: 292 HGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST 351

Query: 367 AQT-SLQPGAKYPDVASPT-LRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNL 424
             T S  P      V  PT      G   T   P ++  + ++    ++ H++    G +
Sbjct: 352 THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS-HSSQDATGTI 410

Query: 425 DSPSGSG---VLSSGSSSPLYSKNVDLNQSP-------LASSPSSAHSAP-SNSLTWGTN 473
             P+ S    +L   ++SP+ S +++    P       L+   ++ HS+P S + T    
Sbjct: 411 VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPA 470

Query: 474 ASSSSAVSKDGLGFQS-VSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVR 532
           +++SS VS++    +S   S HT+  +   S ++ G+  H++++     S D +L P   
Sbjct: 471 STTSSGVSEESTTSRSRPGSTHTT--AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAST 528

Query: 533 TNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPF 592
           T S  +  S +      +T     L    T+ L   +++  +   HS  G   T    P 
Sbjct: 529 TTSGPSQESTTSHSSSGST--DTALSPGSTTALSFGQESTTF---HSNPGSTHTTL-FPD 582

Query: 593 SSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNP------TMLRTHSLSNADGQYDPYT 644
           S+ SS    + TR + S  +  TT++  S ++P      T  +TH  S       P T
Sbjct: 583 STTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPST 640



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 195/947 (20%), Positives = 321/947 (33%), Gaps = 126/947 (13%)

Query: 13   SSSVSSGISDT-IDNLSTDDINTSSSISSYANTPASSRKNLD---------VQTDAEKHS 62
            +S  SSG +DT +   ST  ++     +++ + P S+   L          V+     HS
Sbjct: 539  TSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHS 598

Query: 63   QV--ERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRN--PSDVSDESDKSTSGKKNPVIS 118
                 R +L           G  +  +  P S       PS  +   ++ST+  ++P  +
Sbjct: 599  STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 658

Query: 119  QTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGK--TDDAKVSEKGRLSPKASQVKRS 176
             T  +    T            S+P  +  TP +    T     S   R+SP ++++   
Sbjct: 659  PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTL 718

Query: 177  PSDAGRSSGDESKKPLPSSSRTPT-----ANANSFGFKKQSGSAAGLAMITASGVTVTSR 231
            P         E+     SS R+PT     A+  S G  ++S ++      T S V+  S 
Sbjct: 719  PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS- 777

Query: 232  SATLGKIPKSSALVSRSAG----------RKSSMDG----------AQNQDDGYLALSSR 271
            + T G   +S+ + S S G            +S+ G          A      +   S+ 
Sbjct: 778  TTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTT 837

Query: 272  TNLQYRSLPRP-SKSNSRNGAGNRSSTSSIDSN-----ISSKSAGLPVPKLREPSKTALG 325
            + L   S   P S ++++ G     +T+ +         SS S G  +   R  +   +G
Sbjct: 838  SGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVG 897

Query: 326  SSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVS-----SPAQTSLQPGAKYPDV 380
             S P  ++ +  E      + +  S +         P S     SPA T+    ++    
Sbjct: 898  ESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE---- 953

Query: 381  ASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLD---SPSGSGVLSSGS 437
             S T     G   T   P +T      S +   P  + + QG+ +   SP  +   S G 
Sbjct: 954  ESSTSHSQPGSTHTTAFPDSTT----TSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQ 1009

Query: 438  SSPLYSKNV----------DLNQSPLASSPSSAHSAPSNSLTWGTNASSSSA-VSKDGLG 486
             S  +  +           D   S L  + +  HS+  +  T  T ASS+SA + ++   
Sbjct: 1010 QSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTT 1069

Query: 487  FQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESDPH 546
            FQS  S      S D + S  G  +          S+  S TP    ++  TTL  S+  
Sbjct: 1070 FQSWPS------SSDTTPSPPGTTAAPVEVSTTYHSRPSS-TPTTHFSASSTTLGRSEES 1122

Query: 547  LDRNTLP-KKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTR 605
               ++ P   G    PT                +   L      SP SSGS+ T+     
Sbjct: 1123 TTVHSSPGATGTALFPTRS--------------ATSVLVGEPTTSPISSGSTETT----- 1163

Query: 606  FNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRS 665
                  A P + T   LS  +     S  + D    P + +    S  S    SR  S  
Sbjct: 1164 ------ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTH 1217

Query: 666  GSFRDGFEEVHGSSLSLVSSTSSVYST-----PEEKCQSEIRKLRRELDAS--QEKVSAL 718
             +   G   + G S    +S SS  ST     P     S +        +S    + + L
Sbjct: 1218 TTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLL 1277

Query: 719  TTQLTANAHLVAA--FEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQA 776
                TA+  L A+     S G+    L     T  Q +S       T +          A
Sbjct: 1278 PDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGES------TTFQSWPSSKDTMPA 1331

Query: 777  AINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKR 836
                     EL+   +G+  S         S+    S  S T HSS  +   + S  +  
Sbjct: 1332 PPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARST 1391

Query: 837  KNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGST 883
             + L    +++     SP S  +    E  T S      +  H+ +T
Sbjct: 1392 TSGL---VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTT 1435



 Score = 35.0 bits (79), Expect = 0.54
 Identities = 86/418 (20%), Positives = 155/418 (37%), Gaps = 40/418 (9%)

Query: 102  SDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKP-SAPAGALKTPGTGKTDDAKV 160
            S  S++ST+    P  + T ++  G T   G++   T   S+P     T   G T  + +
Sbjct: 1200 SGVSEESTTSHSRPGSTHTTAFP-GSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSL 1258

Query: 161  SEKGRL---SPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAG 217
              +      SP +++    P +   S   E+  P+ SS+ +P    +  G   + G +  
Sbjct: 1259 GPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 1318

Query: 218  LAMITASGVTVTSRSATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYR 277
                 +S  T+ +   T     + S   + S G  SS               S  +    
Sbjct: 1319 FQSWPSSKDTMPAPPTTTSAFVELS---TTSHGSPSSTPTTHFSASSTTLGRSEESTTVH 1375

Query: 278  SLP-----RPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLV 332
            S P      PS + S        ST+   S  S+++   P       S TA G S     
Sbjct: 1376 SSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFP------ESSTASGRSEESRT 1429

Query: 333  NQTDKEKGISSDNESVASC----NSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRL 388
            + +     ISS   + ++      S   +P +   +   ++S   G      AS +    
Sbjct: 1430 SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDT 1489

Query: 389  FGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSP-LYSKNVD 447
             G  P       +    +++    +P +  T             L+S +++P L +K+  
Sbjct: 1490 NGITPLPAHFTTSGRIAESTTFYISPGSMET------------TLASTATTPGLSAKSTI 1537

Query: 448  LNQSPLASSPSSAHSAPSNSLTWGTNASSS-SAVSKDGLGFQ---SVSSLHTSCESID 501
            L  S L   P++ + +PS + T    ASSS S ++++   F    S +S   S ES++
Sbjct: 1538 LYTSDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLE 1595


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.124    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,839,141
Number of Sequences: 37866
Number of extensions: 2694600
Number of successful extensions: 15283
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 675
Number of HSP's that attempted gapping in prelim test: 11693
Number of HSP's gapped (non-prelim): 3192
length of query: 1493
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1378
effective length of database: 13,892,928
effective search space: 19144454784
effective search space used: 19144454784
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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