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Search of human proteins with 15812226
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
(1200 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 2472 0.0
gi|112807226 hypothetical protein LOC91748 [Homo sapiens] 328 2e-89
gi|44890062 hypothetical protein LOC91748 [Homo sapiens] 328 2e-89
gi|210031154 zinc finger protein 541 [Homo sapiens] 296 1e-79
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 87 7e-17
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 86 2e-16
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 85 4e-16
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 84 8e-16
gi|221139761 zinc finger protein 853 [Homo sapiens] 78 4e-14
gi|93141033 PAX interacting protein 1 [Homo sapiens] 77 8e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 76 2e-13
gi|33286444 mastermind-like 2 [Homo sapiens] 74 6e-13
gi|110347429 mediator complex subunit 12 [Homo sapiens] 74 8e-13
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 70 9e-12
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 70 2e-11
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 69 2e-11
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 69 2e-11
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 67 1e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 67 1e-10
gi|150378539 piccolo isoform 1 [Homo sapiens] 67 1e-10
gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ... 65 3e-10
gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ... 65 3e-10
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 65 3e-10
gi|94721313 mesoderm induction early response 1, family member 3... 65 3e-10
gi|7661892 REST corepressor 1 [Homo sapiens] 65 4e-10
gi|209977084 REST corepressor 3 isoform c [Homo sapiens] 64 7e-10
gi|209977080 REST corepressor 3 isoform a [Homo sapiens] 64 7e-10
gi|8922733 REST corepressor 3 isoform d [Homo sapiens] 64 7e-10
gi|209977082 REST corepressor 3 isoform b [Homo sapiens] 64 9e-10
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 64 1e-09
>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
Length = 1200
Score = 2472 bits (6407), Expect = 0.0
Identities = 1200/1200 (100%), Positives = 1200/1200 (100%)
Query: 1 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD 60
MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
Sbjct: 1 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD 60
Query: 61 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY 120
TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
Sbjct: 61 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY 120
Query: 121 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA 180
QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
Sbjct: 121 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA 180
Query: 181 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL 240
LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
Sbjct: 181 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL 240
Query: 241 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP 300
AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
Sbjct: 241 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP 300
Query: 301 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP 360
QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
Sbjct: 301 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP 360
Query: 361 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML 420
EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
Sbjct: 361 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML 420
Query: 421 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM 480
SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
Sbjct: 421 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM 480
Query: 481 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS 540
HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
Sbjct: 481 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS 540
Query: 541 PNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQ 600
PNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQ
Sbjct: 541 PNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQ 600
Query: 601 GFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEP 660
GFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEP
Sbjct: 601 GFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEP 660
Query: 661 LFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQG 720
LFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQG
Sbjct: 661 LFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQG 720
Query: 721 SGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPR 780
SGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPR
Sbjct: 721 SGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPR 780
Query: 781 INIGLRFQAEIPELQDISALAQDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPG 840
INIGLRFQAEIPELQDISALAQDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPG
Sbjct: 781 INIGLRFQAEIPELQDISALAQDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPG 840
Query: 841 GGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNK 900
GGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNK
Sbjct: 841 GGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNK 900
Query: 901 ALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEE 960
ALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEE
Sbjct: 901 ALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEE 960
Query: 961 LEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNC 1020
LEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNC
Sbjct: 961 LEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNC 1020
Query: 1021 GAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGET 1080
GAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGET
Sbjct: 1021 GAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGET 1080
Query: 1081 DPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVG 1140
DPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVG
Sbjct: 1081 DPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVG 1140
Query: 1141 APGLLPLDQLSLIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL 1200
APGLLPLDQLSLIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
Sbjct: 1141 APGLLPLDQLSLIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL 1200
>gi|112807226 hypothetical protein LOC91748 [Homo sapiens]
Length = 1045
Score = 328 bits (841), Expect = 2e-89
Identities = 304/987 (30%), Positives = 429/987 (43%), Gaps = 152/987 (15%)
Query: 199 SRYQQVPQQPHPGFTGGLSKPAL----QVGQHPTQG-HLYYDYQQPLAQ----------- 242
S +QQ P QP P T +L + HP G YY++ + L +
Sbjct: 119 SSWQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRY 178
Query: 243 --------VPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQ 294
V ++ G+P QAP + S H + +Q P Q Q A +++ Q + P
Sbjct: 179 VRPMMPQKVQLEVGRP-QAP-LNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPP 236
Query: 295 IRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRD 354
P PP +QQQ QQ Q QQ+Q +PQ P+ ++ QQ PS +
Sbjct: 237 PNPVAAFPPQKQQQQQQPQQQQQQQQAALPQ----MPLFENFYSMPQQ------PS--QQ 284
Query: 355 PHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDR 414
P + + A + L S Y P P +P +++ L + R
Sbjct: 285 PQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPR 344
Query: 415 QAQAMLSSHGDLGPPDT-GMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSP 473
+++ LS G L P G G + T + L H PL P L P+ P
Sbjct: 345 RSRR-LSKEGILPPSALDGAGTQPGQEATG-NLFLHHWPLQQPPPGSLGQPHPEALGF-P 401
Query: 474 SAMWPQMHLPDG-RAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLK------------- 519
+ LPDG R P E G+ E A + C L+
Sbjct: 402 LELRESQLLPDGERLAPNGREREAPAMGS-EEGMRAVSTGDCGQVLRGGVIQSTRRRRRA 460
Query: 520 --EFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAE 577
E L + A EE K + P + E
Sbjct: 461 SQEANLLTLAQKAVELASLQNAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDS 520
Query: 578 SLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPS 637
+ P+++PVSVPV+ + P ++Q A + +D + P +H+PS
Sbjct: 521 GMVPLIIPVSVPVRTVDPTEAAQ----------------AGGLDEDGKGPEQNPAEHKPS 564
Query: 638 V----------------PKAEEPLKTVQ-----EKKKFRHRPEPLFIPPPPSYNPNPAAS 676
V +AE+ ++ K K R RPEPL IP P
Sbjct: 565 VIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPV- 623
Query: 677 YSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGA 736
YS T YQS LRSP L DH + + ELPPYTPPP+LSPVR+GSGL+ N +IS A
Sbjct: 624 YSNITPYQSHLRSPVRLADHPS-ERSFELPPYTPPPILSPVREGSGLYFNAIISTSTIPA 682
Query: 737 HPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQT-VDVEPRINIGLRFQAEIPELQ 795
P P+TP + +L S + ++V GE T V +EPRIN+G RFQAEIP ++
Sbjct: 683 PP--PITPKSAHRTLLRTNSAEVTPPVLSVM---GEATPVSIEPRINVGSRFQAEIPLMR 737
Query: 796 DISALAQDTHKATLVWKPWPELEN-HDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFE 854
D + A D HKA LVW+PW +LE+ + Q++VE+LL CSS PG GTN E ALH L E
Sbjct: 738 DRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHE 797
Query: 855 AKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQK 914
++GD++ L LLL+KP+R HPLA YHY GSD+W ERKLFNK +A Y KDF VQK
Sbjct: 798 SRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQK 857
Query: 915 MVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEI-IDDCVTSEEEEELE----------- 962
++++KTVAQCVE+YYT+KK +++GR ++ D +++EE E++
Sbjct: 858 LIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVP 917
Query: 963 --------EEEEEDPEEDRKSTKEEESEVPKSPEPPPVP--------VLAPTEGPPLQAL 1006
EE E E ++ KE E EVP+ E A LQA
Sbjct: 918 LPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRERSRRAAAVKATQTLQAN 977
Query: 1007 GQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCS 1066
S I A S+ + R G K+R A+P ++K
Sbjct: 978 ESASDILILRSHESNAPGSAGGQASEKPREGTG-----KSRRALPFSEKK---------- 1022
Query: 1067 VKSSPSHSTTSGETDPTTIFPCKECGK 1093
K + + S T + + FPCK+CG+
Sbjct: 1023 -KKTETFSKTQNQEN---TFPCKKCGR 1045
>gi|44890062 hypothetical protein LOC91748 [Homo sapiens]
Length = 1045
Score = 328 bits (841), Expect = 2e-89
Identities = 304/987 (30%), Positives = 429/987 (43%), Gaps = 152/987 (15%)
Query: 199 SRYQQVPQQPHPGFTGGLSKPAL----QVGQHPTQG-HLYYDYQQPLAQ----------- 242
S +QQ P QP P T +L + HP G YY++ + L +
Sbjct: 119 SSWQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRY 178
Query: 243 --------VPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQ 294
V ++ G+P QAP + S H + +Q P Q Q A +++ Q + P
Sbjct: 179 VRPMMPQKVQLEVGRP-QAP-LNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPP 236
Query: 295 IRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRD 354
P PP +QQQ QQ Q QQ+Q +PQ P+ ++ QQ PS +
Sbjct: 237 PNPVAAFPPQKQQQQQQPQQQQQQQQAALPQ----MPLFENFYSMPQQ------PS--QQ 284
Query: 355 PHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDR 414
P + + A + L S Y P P +P +++ L + R
Sbjct: 285 PQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPR 344
Query: 415 QAQAMLSSHGDLGPPDT-GMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSP 473
+++ LS G L P G G + T + L H PL P L P+ P
Sbjct: 345 RSRR-LSKEGILPPSALDGAGTQPGQEATG-NLFLHHWPLQQPPPGSLGQPHPEALGF-P 401
Query: 474 SAMWPQMHLPDG-RAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLK------------- 519
+ LPDG R P E G+ E A + C L+
Sbjct: 402 LELRESQLLPDGERLAPNGREREAPAMGS-EEGMRAVSTGDCGQVLRGGVIQSTRRRRRA 460
Query: 520 --EFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAE 577
E L + A EE K + P + E
Sbjct: 461 SQEANLLTLAQKAVELASLQNAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDS 520
Query: 578 SLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPS 637
+ P+++PVSVPV+ + P ++Q A + +D + P +H+PS
Sbjct: 521 GMVPLIIPVSVPVRTVDPTEAAQ----------------AGGLDEDGKGPEQNPAEHKPS 564
Query: 638 V----------------PKAEEPLKTVQ-----EKKKFRHRPEPLFIPPPPSYNPNPAAS 676
V +AE+ ++ K K R RPEPL IP P
Sbjct: 565 VIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPV- 623
Query: 677 YSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGA 736
YS T YQS LRSP L DH + + ELPPYTPPP+LSPVR+GSGL+ N +IS A
Sbjct: 624 YSNITPYQSHLRSPVRLADHPS-ERSFELPPYTPPPILSPVREGSGLYFNAIISTSTIPA 682
Query: 737 HPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQT-VDVEPRINIGLRFQAEIPELQ 795
P P+TP + +L S + ++V GE T V +EPRIN+G RFQAEIP ++
Sbjct: 683 PP--PITPKSAHRTLLRTNSAEVTPPVLSVM---GEATPVSIEPRINVGSRFQAEIPLMR 737
Query: 796 DISALAQDTHKATLVWKPWPELEN-HDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFE 854
D + A D HKA LVW+PW +LE+ + Q++VE+LL CSS PG GTN E ALH L E
Sbjct: 738 DRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHE 797
Query: 855 AKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQK 914
++GD++ L LLL+KP+R HPLA YHY GSD+W ERKLFNK +A Y KDF VQK
Sbjct: 798 SRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQK 857
Query: 915 MVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEI-IDDCVTSEEEEELE----------- 962
++++KTVAQCVE+YYT+KK +++GR ++ D +++EE E++
Sbjct: 858 LIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVP 917
Query: 963 --------EEEEEDPEEDRKSTKEEESEVPKSPEPPPVP--------VLAPTEGPPLQAL 1006
EE E E ++ KE E EVP+ E A LQA
Sbjct: 918 LPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRERSRRAAAVKATQTLQAN 977
Query: 1007 GQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCS 1066
S I A S+ + R G K+R A+P ++K
Sbjct: 978 ESASDILILRSHESNAPGSAGGQASEKPREGTG-----KSRRALPFSEKK---------- 1022
Query: 1067 VKSSPSHSTTSGETDPTTIFPCKECGK 1093
K + + S T + + FPCK+CG+
Sbjct: 1023 -KKTETFSKTQNQEN---TFPCKKCGR 1045
>gi|210031154 zinc finger protein 541 [Homo sapiens]
Length = 1365
Score = 296 bits (757), Expect = 1e-79
Identities = 230/717 (32%), Positives = 323/717 (45%), Gaps = 145/717 (20%)
Query: 401 QREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIH 460
++E +++ + +Q ++S GPP DP+ S LT S P +
Sbjct: 758 RKEKAKMDMCCAASPSQVAMASFSSAGPP----ADPSKSKLTIFSRIQGGNIYRLPHPVK 813
Query: 461 LNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKE 520
N+ + G Q GSP +P+ F C C +
Sbjct: 814 EENVAGR-----------------GNQQNGSPTDWTKPRSTF----------VCKNCSQM 846
Query: 521 FKNLPALNGHMRSHGGMRASPNLKQEE---GEKVLPPQPQPPLPPPPPPPPP-PQLPPEA 576
F L+ HM H SP KQE G + P Q P PP + P +
Sbjct: 847 FYTEKGLSSHMCFHSDQWPSPRGKQEPQVFGTEFCKPLRQVLRPEGDRHSPPGTKKPLDP 906
Query: 577 ESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQP 636
+ P+V+P S+PV P ++ + + +R A++ + E + +
Sbjct: 907 TAAAPLVVPQSIPVV-----PVTRHIGSMAMMEWCSRWLQATTCGSKLLQGQEKDGEERD 961
Query: 637 SVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDH 696
S K +++K + RP PP + P PA + QS+LRSP L D
Sbjct: 962 S--------KESSQQRKRKKRP-----PPSTAGEPGPAGCH------QSRLRSPMFLVD- 1001
Query: 697 LLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRS 756
LL + PYTPPPMLSP+R+GSG++ N L S + QL + L
Sbjct: 1002 CLLKGLFQCSPYTPPPMLSPIREGSGVYFNTLCSTSTQASPDQLISSML----------- 1050
Query: 757 NSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQDTHKATLVWKPWPE 816
+ +DGS + + + +EP INIG RFQAEIPELQ+ S D H A+LVWKPW +
Sbjct: 1051 DQVDGS-FGICVVKDDTKISIEPHINIGSRFQAEIPELQERSLAGTDEHVASLVWKPWGD 1109
Query: 817 LE-NHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLK 875
+ + + Q RV L N+ CSS +PGGGTN E ALH L EA+G+V VALE LLLR P + +
Sbjct: 1110 MMISSETQDRVTELCNVACSSVMPGGGTNLELALHCLHEAQGNVQVALETLLLRGPHKPR 1169
Query: 876 CHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIM 935
H LA+Y Y GSD WT +E++LF KA + KDF + KM+++KTVAQCVEYYY WKK++
Sbjct: 1170 THLLADYRYTGSDVWTPIEKRLFKKAFYAHKKDFYLIHKMIQTKTVAQCVEYYYIWKKMI 1229
Query: 936 RLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVL 995
+ DC + LE+ + +PEE ++ E +VP SP P
Sbjct: 1230 KF-------------DCGRAPG---LEKRVKREPEEVERT----EEKVPCSPRERPSH-- 1267
Query: 996 APTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQ 1055
PT P L+ S + PN G+
Sbjct: 1268 HPT--PKLKTKSYRRESILSSSPNAGS--------------------------------- 1292
Query: 1056 KPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNAHMKTHRQQE 1112
K +P G + IFPC+EC +VF KIKSRNAHMK HR Q+
Sbjct: 1293 ------------KRTPE---LLGSAESQGIFPCRECERVFDKIKSRNAHMKRHRLQD 1334
Score = 39.7 bits (91), Expect = 0.017
Identities = 18/61 (29%), Positives = 27/61 (44%)
Query: 1080 TDPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPV 1139
T P + F CK C ++F+ K ++HM H Q R K + F E + + P
Sbjct: 832 TKPRSTFVCKNCSQMFYTEKGLSSHMCFHSDQWPSPRGKQEPQVFGTEFCKPLRQVLRPE 891
Query: 1140 G 1140
G
Sbjct: 892 G 892
Score = 32.7 bits (73), Expect = 2.1
Identities = 55/222 (24%), Positives = 76/222 (34%), Gaps = 55/222 (24%)
Query: 509 KNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEG-------------------- 548
+ K C IC K FK L GHM +H + P + E+G
Sbjct: 165 ERKHVCKICSKAFKRQDHLTGHMLTH--QKTKPFVCIEQGCSKSYCDYRSLRRHYEVHHG 222
Query: 549 ---EKVLPPQPQ-----PPLPPPPPPPPPPQL----PPEAES---------LTPMVMPVS 587
K PP+ + P PPP L PPEA S L ++
Sbjct: 223 LCILKEAPPEEEACGDSPHAHESAGQPPPSSLRSLVPPEARSPGSLLPHRDLLRRIVSSI 282
Query: 588 VPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMP--------VLEIPRKHQPSVP 639
V K P P+ G ++S +A PASS S P L+ +P +P
Sbjct: 283 VHQKTPSPGPAPAGASDSE-GRNTACPCPASSGSSSCTPAGPHAAPAALDTELPEEPCLP 341
Query: 640 KAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGAT 681
+ +EP V R P PP P+ A + +T
Sbjct: 342 Q-KEPATDVFTAPNSRAAENG--APDPPEPEPDTALLQARST 380
Score = 31.6 bits (70), Expect = 4.7
Identities = 19/75 (25%), Positives = 30/75 (40%), Gaps = 5/75 (6%)
Query: 1048 GAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNAHMKT 1107
G + + + GG + + K HS+ + C CGKVF S + H T
Sbjct: 107 GVLKAKEADEGGRATSGSARKGKRQHSSPQNP-----LLDCSLCGKVFSSASSLSKHYLT 161
Query: 1108 HRQQEEQQRQKAQKA 1122
H Q+ + + KA
Sbjct: 162 HSQERKHVCKICSKA 176
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 87.4 bits (215), Expect = 7e-17
Identities = 129/467 (27%), Positives = 167/467 (35%), Gaps = 93/467 (19%)
Query: 167 HTQSAVMDGAPDSALR--------QLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSK 218
H+ + V P + L+ Q Q+ + A+ + QQ QQ + +
Sbjct: 139 HSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQ 198
Query: 219 PALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQA 278
V Q Q QQ L ++ Q Q +Q Q Q + Q+Q Q QQQQQ
Sbjct: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQ----QQQQQQ 254
Query: 279 GQQRISMQEIQTQP--QQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHL 336
QQ+ Q +Q QP QQ QPQPPP Q PQQLQ M Q++QP P Q
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQ------QMHHTQHHQPPPQPQ-- 306
Query: 337 QEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQ------YYYQEP-------- 382
QPP P Q P+ Q PL S +Q Y Q P
Sbjct: 307 ----------QPPVAQNQPSQLPPQS----QTQPLVSQAQALPGQMLYTQPPLKFVRAPM 352
Query: 383 --QQPYSHPLYQQSH-----------LSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPP 429
QQP P QQ ++ Q S L SS Q + + PP
Sbjct: 353 VVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP 412
Query: 430 DTG--MGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQ---MHLPD 484
G P+S + VSS P SPS L + PQ Q +A PQ + P
Sbjct: 413 QPSPQPGQPSSQPNSNVSS----GPAPSPSSF-LPSPSPQPSQSPVTARTPQNFSVPSPG 467
Query: 485 GRAQPGSPESSGQPKG---AFGEQFDAKNKLTCSIC--LKEFKNLPALN-------GHMR 532
P +P S P G A +Q+ K K L+ N N M+
Sbjct: 468 PLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMK 527
Query: 533 SHGGMRASPN--------LKQEEGEKVLPPQPQPPLPPPPPPPPPPQ 571
S + P+ K E + L P PPPPP PP Q
Sbjct: 528 SLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQ 574
Score = 73.6 bits (179), Expect = 1e-12
Identities = 131/534 (24%), Positives = 186/534 (34%), Gaps = 98/534 (18%)
Query: 211 GFTGGLSKPALQVGQHP--TQG---HLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQ 265
G G + +P GQ P T G H Q +Q Q Q Q QQ Q
Sbjct: 114 GSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQ 173
Query: 266 QHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQL---------QLQQ 316
Q QQQQQ Q + +Q Q Q + Q Q QQQQ Q L Q+QQ
Sbjct: 174 QAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQ 233
Query: 317 RQGSMQIP---QYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGS 373
+Q +Q Q Q Q Q Q+QQQQ + QPP Q P + Q +P
Sbjct: 234 QQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPS---QALPQQL 290
Query: 374 MSQYYYQEPQQPYSHPLYQQSHLSQHQQRE-DSQLKTYSSDRQAQAMLSSHGDLGPPDTG 432
++ Q Q P P QQ ++Q+Q + Q +T QAQA+ PP
Sbjct: 291 QQMHHTQHHQPP---PQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKF 347
Query: 433 MGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSP 492
+ P V P +P + Q Q +A QM P + S
Sbjct: 348 VRAP------MVVQQPPVQPQVQ-----------QQQTAVQTAQAAQMVAPGVQVSQSSL 390
Query: 493 ESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVL 552
P G+Q +++P G + PN G
Sbjct: 391 PMLSSPSP--GQQVQTP------------QSMPPPPQPSPQPGQPSSQPNSNVSSG---- 432
Query: 553 PPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSA 612
P P P P P P P Q P A TP V P L +T PS+
Sbjct: 433 -PAPSPSSFLPSPSPQPSQSPVTAR--TPQNFSVPSPGPL------------NTPVNPSS 477
Query: 613 RDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTV-------QEKKKFRHRPEPLFIPP 665
PA S +E L+ ++ + K EPL+ + +++KK + + L
Sbjct: 478 VMSPAGSSQAEEQQYLDKLKQ----LSKYIEPLRRMINKIDKNEDRKKDLSKMKSLL--- 530
Query: 666 PPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQ 719
+P+ TL + ++ ++ D + P PPP + P +Q
Sbjct: 531 --DILTDPSKRCPLKTLQKCEIALEKLKNDMAV--------PTPPPPPVPPTKQ 574
Score = 50.1 bits (118), Expect = 1e-05
Identities = 49/235 (20%), Positives = 85/235 (36%), Gaps = 43/235 (18%)
Query: 544 KQEEGEKVLPPQPQPPLPPPPPPP------------------PPP-------------QL 572
+Q++ + PP QPP+ P PPP PPP QL
Sbjct: 259 QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQL 318
Query: 573 PPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPR 632
PP++++ + ++P ++L +P + F + + +P + + +
Sbjct: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLK-FVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQ 377
Query: 633 KHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRV 692
P V ++ L + + P +PPPP +P P S S +P
Sbjct: 378 MVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAP-- 435
Query: 693 LGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTP 747
P+ LP +P P SPV + N + GP P P + ++P
Sbjct: 436 -------SPSSFLPSPSPQPSQSPVTARTP--QNFSVPSPGPLNTPVNPSSVMSP 481
Score = 46.6 bits (109), Expect = 1e-04
Identities = 55/215 (25%), Positives = 76/215 (35%), Gaps = 28/215 (13%)
Query: 148 QVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQ 207
Q A L+ Q Q Q + P ++Q Q+P PP+ A+P + QQ+
Sbjct: 239 QRIAQLQLQQQQQQQQQQQQQQQQALQAQPP--IQQPPMQQPQPPPSQALPQQLQQMHHT 296
Query: 208 PHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPL---------QAPQMLS 258
H +P + Q P+Q Q ++Q GQ L +AP ++
Sbjct: 297 QHHQPPPQPQQPPVAQNQ-PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQ 355
Query: 259 QHMQQMQQHQYYPPQQQQQAGQQ-----RISMQEI----------QTQPQQIRPSQPQPP 303
Q Q Q Q Q QA Q ++S + Q Q Q P PQP
Sbjct: 356 QPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPS 415
Query: 304 PQQQQP-QQLQLQQRQGSMQIPQYYQPQPMMQHLQ 337
PQ QP Q G P + P P Q Q
Sbjct: 416 PQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ 450
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 86.3 bits (212), Expect = 2e-16
Identities = 104/409 (25%), Positives = 152/409 (37%), Gaps = 48/409 (11%)
Query: 273 QQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPM 332
QQQQQ QQ+ Q+ Q Q Q + +Q Q QQ Q Q Q + P PM
Sbjct: 1723 QQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPM 1782
Query: 333 MQHLQEQQQQQMHLQPPSY------HRDPHQYTPEQAHTVQLIPLG-----------SMS 375
Q QQQ HL P Y +P P + + L G +
Sbjct: 1783 TTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVP 1842
Query: 376 QYYYQE--PQQPYSHPLYQQSHL-----SQHQQREDSQL---KTYSSDRQAQAMLSSHGD 425
Q +Q+ PQQ + QSH SQH ++++ + K S R+ + G+
Sbjct: 1843 QQSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEGN 1902
Query: 426 LGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDG 485
GP +T + + ++ P + P I + G + L + + +
Sbjct: 1903 TGPKETLPDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELV----- 1957
Query: 486 RAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQ 545
Q + Q K +Q + KL C C K F N+ L H + H P +
Sbjct: 1958 -IQYNENKQKVQKKNGKTDQGENLEKLECDSCGKLFSNILILKSH-QEHVHQNYFPFKQL 2015
Query: 546 EEGEK-----------VLPPQPQPPLPPPPPPPPP-PQLPPEAESLTPMVMPVSVPVKLL 593
E K + P P+PP PPPPPPPPP P PP+ S TP + P S P
Sbjct: 2016 ERFAKQYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPAS-TPAI-PASAPPITS 2073
Query: 594 PPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAE 642
P +Q T + S + MP+ +P + P + E
Sbjct: 2074 PTIAPAQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVE 2122
Score = 41.2 bits (95), Expect = 0.006
Identities = 81/340 (23%), Positives = 120/340 (35%), Gaps = 52/340 (15%)
Query: 235 DYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQ 294
D + LA+ P QP Q + Q ++QQ + P+Q+ QQ++ PQ
Sbjct: 2427 DEKPKLAEAP--SAQPNQTQEKQGQPKPELQQQEQ--PEQKTNTPQQKL--------PQL 2474
Query: 295 IR-PSQPQPPPQQQQPQQLQLQQRQGSMQI------PQYYQPQPMMQHLQEQ----QQQQ 343
+ PS PQPPPQ PQ Q Q+ P + + +L Q Q Q
Sbjct: 2475 VSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQ 2534
Query: 344 MHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPY-----SHPLYQQSHLS- 397
L PS+ H +Q H + Q+ + P+ S+PL LS
Sbjct: 2535 CKLAFPSFE---HWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSG 2591
Query: 398 ----------QHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSST 447
S + T + +A S G D+G G R+ +T
Sbjct: 2592 AIPQIPASSATSPSTPTSTMNTLKRKLEEKASASP----GENDSGTGGEEPQRDKRLRTT 2647
Query: 448 LPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPES-SGQPKGAFGEQF 506
+ L +L + P + L A ++ L Q + + + KG F
Sbjct: 2648 ITPEQLEILYQKYLLDSNPTRKMLDHIA--HEVGLKKRVVQVWFQNTRARERKGQFRAVG 2705
Query: 507 DAKNKLTCSICLKEFKNLPALNGHMRS---HGGMRASPNL 543
A+ C C FK AL H+RS H RA NL
Sbjct: 2706 PAQAHRRCPFCRALFKAKTALEAHIRSRHWHEAKRAGYNL 2745
Score = 40.0 bits (92), Expect = 0.013
Identities = 81/379 (21%), Positives = 129/379 (34%), Gaps = 65/379 (17%)
Query: 184 LLSQKP--MEPPAPAIPSRYQQVPQQPHPGFTGGLSKPA-----LQVG-QHPTQGHLYYD 235
L S KP M P+ +PS P+ + LS P + +G Q P Q
Sbjct: 3144 LTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQ 3203
Query: 236 YQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQR-----ISMQEIQT 290
Q P QP PQ+ Q QQ + +++++A + + + +E
Sbjct: 3204 QPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKGE 3263
Query: 291 QPQQIRPSQPQPPPQQQ---QPQQLQLQQRQGSM--------QIPQYYQP--QPMMQHLQ 337
P + P P + P QLQ Q + Q Y+ P P
Sbjct: 3264 APTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQI 3323
Query: 338 EQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLS 397
Q +LQP Y+P + + + GS+ Q Y Q YQQS
Sbjct: 3324 PGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQ----------YQQSLQE 3373
Query: 398 QHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPS 457
QQ++ QL+ + Q + PP G P+ S P +P
Sbjct: 3374 AIQQQQQRQLQQQQQQKVQQQQPKASQTPVPP----GAPSPDKDPAKESPKPEEQKNTP- 3428
Query: 458 GIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQF---DAKNKLTC 514
+++SP + P++ P PE+ + + + F + KL C
Sbjct: 3429 -----------REVSP--LLPKL--------PEEPEAESKSADSLYDPFIVPKVQYKLVC 3467
Query: 515 SICLKEFKNLPALNGHMRS 533
C F + A H++S
Sbjct: 3468 RKCQAGFSDEEAARSHLKS 3486
Score = 35.8 bits (81), Expect = 0.25
Identities = 18/45 (40%), Positives = 24/45 (53%)
Query: 938 GRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESE 982
G K + + V EEE EEEEEE+ EE+ + +EEE E
Sbjct: 441 GEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEE 485
Score = 35.0 bits (79), Expect = 0.43
Identities = 18/49 (36%), Positives = 26/49 (53%)
Query: 951 DCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTE 999
DC + + E EE EEE+ EE+ + +EEE E + E L P+E
Sbjct: 450 DCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSE 498
Score = 35.0 bits (79), Expect = 0.43
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 946 AEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGPPLQA 1005
+E ++ EEEE EEE EE+ EE+ + +EEE E K P + E P +
Sbjct: 453 SEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELD--EELEDRPHEE 510
Query: 1006 LGQPSGS 1012
G +GS
Sbjct: 511 PGAAAGS 517
Score = 35.0 bits (79), Expect = 0.43
Identities = 26/66 (39%), Positives = 30/66 (45%), Gaps = 15/66 (22%)
Query: 541 PNLKQEEG--EKVLPPQ---PQ----PPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVK 591
P L+Q+E +K PQ PQ P LP PPP PPPQ P P P +
Sbjct: 2452 PELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCP------LPQSSPSPSQLS 2505
Query: 592 LLPPKP 597
LP KP
Sbjct: 2506 HLPLKP 2511
Score = 35.0 bits (79), Expect = 0.43
Identities = 14/29 (48%), Positives = 18/29 (62%)
Query: 545 QEEGEKVLPPQPQPPLPPPPPPPPPPQLP 573
Q++ ++ P QPP PP PPP PQLP
Sbjct: 3197 QQQQQQQQPQVQQPPPPPAAQPPPTPQLP 3225
Score = 33.9 bits (76), Expect = 0.95
Identities = 33/166 (19%), Positives = 64/166 (38%), Gaps = 24/166 (14%)
Query: 960 ELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGP--PLQALGQPSGSFICEM 1017
E ++EEE D E+ + T + V + P L +GP ++ PS + C +
Sbjct: 1490 EEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTV 1549
Query: 1018 PNCGAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTS 1077
C F+ + L H +++ +A +G+ +P T+S
Sbjct: 1550 --CKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEP-----------------TSS 1590
Query: 1078 GETDPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAA 1123
+ P F C C + + + HM++ Q + + K + A+
Sbjct: 1591 PDNKP---FKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAAS 1633
Score = 33.1 bits (74), Expect = 1.6
Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 24/88 (27%)
Query: 543 LKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGF 602
L+Q++ +KV QP+ P PP P P P ES PKP Q
Sbjct: 3383 LQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKES----------------PKPEEQKN 3426
Query: 603 TNSTVA--------APSARDKPASSMSD 622
T V+ P A K A S+ D
Sbjct: 3427 TPREVSPLLPKLPEEPEAESKSADSLYD 3454
Score = 32.7 bits (73), Expect = 2.1
Identities = 31/125 (24%), Positives = 47/125 (37%), Gaps = 21/125 (16%)
Query: 554 PQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSAR 613
P P L PP P P TP L PKP+ G ++TV +P
Sbjct: 3112 PTAYPALQGIPPVLLPGLNSPSLPGFTPS------NTALTSPKPNLMGLPSTTVPSPGLP 3165
Query: 614 -----DKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPS 668
+KP+S+ P A P + Q++++ + +P+ PPPP+
Sbjct: 3166 TSGLPNKPSSASLSSPTPA---------QATMAMGPQQPPQQQQQ-QQQPQVQQPPPPPA 3215
Query: 669 YNPNP 673
P P
Sbjct: 3216 AQPPP 3220
Score = 32.3 bits (72), Expect = 2.8
Identities = 17/42 (40%), Positives = 23/42 (54%)
Query: 947 EIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPE 988
E+ D SE+ E EEE EE+ EE+ +EEE E + E
Sbjct: 445 EVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEEEEE 486
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 85.1 bits (209), Expect = 4e-16
Identities = 196/814 (24%), Positives = 279/814 (34%), Gaps = 96/814 (11%)
Query: 37 GNAVTGGGMDAPQASPISPHFP-QDTRDGLGLP-------VGSKNLGQMDTSRQGGWGSH 88
G + G G+ PQ P + T G+ LP + + Q GG GS
Sbjct: 3633 GQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSL 3692
Query: 89 AGPGNHVQLRGNLANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLHKLDSFTQ 148
AGP GNLA ++ G Q +++ Q+ + KL
Sbjct: 3693 AGPSGGF-FPGNLALRSL------------GPDSRLLQERQLQLQQQRMQLAQKLQQ--- 3736
Query: 149 VFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKP--MEPPAPAIPSRYQQVPQ 206
Q + Q + + QV Q P Q L KP + PP+ QQ+
Sbjct: 3737 --QQQQQQQQQHLLGQVAIQQQ--QQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSP 3792
Query: 207 QPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQ 266
QP G G L + V Q G L Q P QV + + L +PQ L+Q Q +
Sbjct: 3793 QPPQGPQGMLGPAQVAVLQQQHPGAL--GPQGPHRQVLMTQSRVLSSPQ-LAQQGQGLMG 3849
Query: 267 HQYYPPQQQQQ-----------------------AGQQRIS------MQEIQTQPQQIRP 297
H+ QQQQQ +GQ ++S +Q++Q Q Q +
Sbjct: 3850 HRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQ 3909
Query: 298 SQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQ 357
Q Q QQQ QQ QLQQ+Q Q Q Q Q LQ+QQQQ Q + Q
Sbjct: 3910 QQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQ 3969
Query: 358 YTPEQAHTV-QLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQA 416
+Q + Q L S Q Q+ P H S + L T
Sbjct: 3970 QQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTV 4029
Query: 417 QAMLSSHGDLGPPDTGMGDPASSDLTRVS-STLPHRPLLSPSG-IHLNNMGPQHQ-QLSP 473
+SS G P T G P + T S +T P S SG L + PQ Q Q S
Sbjct: 4030 DPAVSSEATEG-PSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSS 4088
Query: 474 SAMWPQMHLPDGRAQPGS--PESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHM 531
+ P + LP + Q S + G G G ++ + + +L G M
Sbjct: 4089 LQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSM 4148
Query: 532 RSH--GGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPM--VMPVS 587
+ G + + PP+P P L P +P + + V+ +
Sbjct: 4149 TQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKN 4208
Query: 588 VPVKLLPPKPSSQ----GFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEE 643
++ L P+ Q + + R P + L+ QP +
Sbjct: 4209 PQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPG 4268
Query: 644 PLKTVQEKKKFRHRPE-PLFIPPPPS----------YNPNPAASYSGATLYQSQLRSP-R 691
P ++ RP+ P +P PP +P P S SQL SP
Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328
Query: 692 VLGDHLLLDPTHELPPYTPPPMLSP----VRQGSGLFSNVLIS-GHGPGAHPQLPLTPLT 746
L L PTH P P L P V + ++ L S G GP P
Sbjct: 4329 QLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQK 4388
Query: 747 PTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPR 780
P L+ +D N V P + ++ EPR
Sbjct: 4389 PEQSSLV--PGHLDQVNGQVVPEASQLSIKQEPR 4420
Score = 63.9 bits (154), Expect = 9e-10
Identities = 129/543 (23%), Positives = 183/543 (33%), Gaps = 101/543 (18%)
Query: 277 QAGQQRISMQEIQTQPQQIRPSQPQP-PPQQQQPQQL----QLQQRQGSMQIPQYYQPQP 331
Q GQ S+ E T P R S P+P +P L Q Q + G + Q +P P
Sbjct: 353 QGGQTIRSVAEQHT-PVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGP 411
Query: 332 MM--------------QHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQY 377
+ L+ ++M L PP P PE++ T +S
Sbjct: 412 LQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPP-EESPLSPPPEESPTSPPPEASRLSP- 469
Query: 378 YYQEPQQPYSHPLYQQSHLSQHQQR-------EDSQLKTYSSDRQAQAMLSSHGDLGPPD 430
P++ + PL + HLS+ + E+S L + S L PP+
Sbjct: 470 ---PPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES--PLSPPE 524
Query: 431 TGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPG 490
PA L S P LSP + + P ++L S P A
Sbjct: 525 ESPPSPA---LETPLSPPPEASPLSPP-FEESPLSPPPEELPTS--------PPPEASRL 572
Query: 491 SPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEK 550
SP P E+ S F+ P SP E +
Sbjct: 573 SPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL-------SPPPEESPLSPPPEASR 625
Query: 551 VLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVM-----------PVSVPVKLLPPKPSS 599
+ PP P+ PPP P PPE L+P+ + P+S P + P P
Sbjct: 626 LSPPPEDSPMSPPPEESPMSP-PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPP 684
Query: 600 QGFTNS-----TVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEP---------- 644
+ S + +P D PAS +D + + +P + P +P EEP
Sbjct: 685 EASRLSPPPEDSPTSPPPEDSPASPPPEDSL--MSLPLEESPLLPLPEEPQLCPRSEGPH 742
Query: 645 LKTVQEKKKFRHRPEPLFIPP---PPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDP 701
L E+ RPE + P P +P P A + L SP+ G HL P
Sbjct: 743 LSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL-SPQAEGPHLSPQP 801
Query: 702 TH-ELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAH--------------PQLPLTPLT 746
L P T P LSPV + L S P + P+L PL+
Sbjct: 802 EELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLS 861
Query: 747 PTP 749
P P
Sbjct: 862 PRP 864
Score = 59.3 bits (142), Expect = 2e-08
Identities = 164/782 (20%), Positives = 248/782 (31%), Gaps = 158/782 (20%)
Query: 177 PDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDY 236
P+S+ L + P+ PP + PS + P P P LS P + P L
Sbjct: 507 PESSPFSPLEESPLSPPEESPPSPALETPLSPPPE-ASPLSPPFEESPLSPPPEELPTSP 565
Query: 237 QQPLAQV-PVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQI 295
+++ P P+ P S + + +PP ++ + P+
Sbjct: 566 PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP-EESPLSPPPEAS 624
Query: 296 RPSQP------QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPP 349
R S P PPP++ R + + P P L ++ PP
Sbjct: 625 RLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPP 684
Query: 350 SYHR----------------DPHQYTPEQA------HTVQLIPLGSMSQ--------YYY 379
R P PE + L+PL Q +
Sbjct: 685 EASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLS 744
Query: 380 QEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASS 439
P++P+ P ++ HLS Q E+ L + + L P G
Sbjct: 745 PRPEEPHLSPRPEEPHLSP--QAEEPHLSP-QPEEPCLCAVPEEPHLSPQAEGPHLSPQP 801
Query: 440 DLTRVS--------STLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHL-PDGRAQPG 490
+ +S S +P P LSP +++ PQ ++ S + HL P+ P
Sbjct: 802 EELHLSPQTEEPHLSPVPEEPCLSPQPEE-SHLSPQSEEPCLSPRPEESHLSPELEKPPL 860
Query: 491 SPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQE---- 546
SP P+ Q A +L E P L S G L +E
Sbjct: 861 SPRPEKPPEEP--GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS 918
Query: 547 -EGEKVLPPQPQPPLPPPPPPPP------PPQLPP------------EAESLTPMVMPV- 586
GE L PQ PP P PPP P PP L P +++ +P+ P+
Sbjct: 919 PSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPIL 978
Query: 587 ----------------SVPVKLLPPKPSSQ-GFTNSTVAAP-------------SARDKP 616
VP +LPP P S G + + P ++ P
Sbjct: 979 ETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSP 1038
Query: 617 ASSMSDDEMPVLEIP----------------RKHQPSVPKAEEPLKTVQEKKKFRHRPEP 660
S S +P L +P H+ K EP E P P
Sbjct: 1039 PSQCSPPALP-LSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSP 1097
Query: 661 LFIPPPPSYNPNPA-----------ASYSGATLYQSQLR--------SPRVLGDHLLLDP 701
+ P+ +P PA A G SQ + + G +LLDP
Sbjct: 1098 MGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDP 1157
Query: 702 THELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSIDG 761
EL P TP + +Q +G S P + P P+ PTP L+ +
Sbjct: 1158 -EELAPVTPMEVYPECKQTAGQGS--------PCEEQEEPRAPVAPTPPTLIKSDIVNEI 1208
Query: 762 SNVTVTPG----PGEQTVDVEPRINIGLRFQAEIPELQDISALAQDTHKATLVWKPWPEL 817
SN++ PG + + P G E+ D+S A+D L PE
Sbjct: 1209 SNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSP-ARDEGSLRLCTDSLPET 1267
Query: 818 EN 819
++
Sbjct: 1268 DD 1269
Score = 54.7 bits (130), Expect = 5e-07
Identities = 90/350 (25%), Positives = 125/350 (35%), Gaps = 56/350 (16%)
Query: 447 TLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPES-----SGQPKGA 501
+L HR + G + ++ QH + P+ G P++ GQPKG
Sbjct: 344 SLCHRCHKAQGGQTIRSVAEQHTPVCSRFSPPE----PGDTPTDEPDALYVACQGQPKGG 399
Query: 502 FGEQFDAKNK--LTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKV--LPPQPQ 557
K L C E K L G++ P L+ E++ LPP +
Sbjct: 400 HVTSMQPKEPGPLQC-----EAKPL--------GKAGVQLEPQLEAPLNEEMPLLPPPEE 446
Query: 558 PPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPA 617
PL PPP P PPEA L+P P + LP P + S S P
Sbjct: 447 SPLSPPPEESPTSP-PPEASRLSP-------PPEELPASPLPEALHLSRPLEESPLSPP- 497
Query: 618 SSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNP-NPAAS 676
+E P L P + P P E PL +E PL PPP +P +P
Sbjct: 498 ----PEESP-LSPPPESSPFSPLEESPLSPPEESPPSPALETPL--SPPPEASPLSPPFE 550
Query: 677 YSGATLYQSQL-RSPRVLGDHLLLDPTHELPPYTPPP---MLSPVRQGSGLFSNVLISGH 732
S + +L SP L P E P +PPP +SP + S LF S
Sbjct: 551 ESPLSPPPEELPTSPPPEASR--LSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL 608
Query: 733 GPGAHPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRIN 782
P +PL+P P D ++P P E + P ++
Sbjct: 609 SPPPEE----SPLSPPPEASRLSPPPEDS---PMSPPPEESPMSPPPEVS 651
Score = 47.4 bits (111), Expect = 8e-05
Identities = 68/260 (26%), Positives = 95/260 (36%), Gaps = 37/260 (14%)
Query: 249 QPLQAPQMLSQHMQQMQQH-----QYYPPQQQQQAGQQRISMQE--------------IQ 289
Q + + L Q +Q ++H +Y QQQQQ QQ+ Q +
Sbjct: 3570 QQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLT 3629
Query: 290 TQPQQIRPSQPQPPPQQQQPQQL-QLQQRQGSMQIPQYYQP-QPMMQHLQEQQQQQMHLQ 347
P Q+ P PPQ Q L+ G M +P QP P + QQQQQ H
Sbjct: 3630 KLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPG--QPGGPFLNTALAQQQQQQHSG 3687
Query: 348 PPSYHRDPH-QYTPEQAHTVQLIP---LGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQRE 403
P + P L P L Q Q+ + + L QQ Q QQ
Sbjct: 3688 GAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHL 3747
Query: 404 DSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNN 463
Q+ +Q + ++ LGP G+ P+S V P +P P G+
Sbjct: 3748 LGQVAIQQQQQQGPGVQTNQA-LGPKPQGLMPPSSHQGLLVQQLSP-QPPQGPQGM---- 3801
Query: 464 MGPQH----QQLSPSAMWPQ 479
+GP QQ P A+ PQ
Sbjct: 3802 LGPAQVAVLQQQHPGALGPQ 3821
Score = 40.8 bits (94), Expect = 0.008
Identities = 39/132 (29%), Positives = 53/132 (40%), Gaps = 20/132 (15%)
Query: 554 PQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSAR 613
P QPPL P P PPP P +L P +P S P +P P SQ + S +
Sbjct: 2377 PYAQPPLTPRPQPPP----PESCCALPPRSLP-SDPFSRVPASPQSQSSSQSPLT----- 2426
Query: 614 DKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNP 673
+P S+ + PV PR P +P + + R PL PP P P
Sbjct: 2427 PRPLSAEAFCPSPV--TPRFQSP------DPYSRPPSRPQSRDPFAPLHKPPRP--QPPE 2476
Query: 674 AASYSGATLYQS 685
A +G+ + S
Sbjct: 2477 VAFKAGSLAHTS 2488
Score = 38.5 bits (88), Expect = 0.039
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 6/89 (6%)
Query: 542 NLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQG 601
N+ + ++ P P+ P PPP P P P PP P+V + P+ PP PS
Sbjct: 4897 NVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPP----TEPLVELPTEPL-AEPPVPSPLP 4951
Query: 602 FTNSTVAA-PSARDKPASSMSDDEMPVLE 629
+S +A P R +P D P L+
Sbjct: 4952 LASSPESARPKPRARPPEEGEDSRPPRLK 4980
Score = 36.2 bits (82), Expect = 0.19
Identities = 84/411 (20%), Positives = 132/411 (32%), Gaps = 35/411 (8%)
Query: 282 RISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQ--RQGSMQIPQYYQPQPMMQHLQEQ 339
R S E Q+ +RP +P PP Q P R GS P Y QP +
Sbjct: 2334 RASQVEPQSPGLGLRPQEP-PPAQALAPSPPSHPDIFRPGSYTDP-YAQPPLTPRPQPPP 2391
Query: 340 QQQQMHLQPPSYHRDPHQYTP-----EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQS 394
+ L P S DP P + + L P ++ + P P S
Sbjct: 2392 PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451
Query: 395 HLSQHQQREDSQLKTYSSDR-QAQAMLSSHGDLGPPDTGMGD--------PASSDLTRVS 445
Q D + R Q + G L G G PA +V
Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511
Query: 446 STLPHRPLLSP-SGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGE 504
S P + SP +G + P + P + P QPG P P
Sbjct: 2512 SGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPV--PQPGLP-----PPHGINS 2564
Query: 505 QFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPP 564
F L + N G+ G + E + P +P LPPP
Sbjct: 2565 HFGPGPTLG----KPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPA 2620
Query: 565 PPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDE 624
P P L A + ++ PV+ + G + +T P +D S +S E
Sbjct: 2621 PDGSLPYLSHGASQRS----GITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTE 2676
Query: 625 MPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAA 675
+ ++ + + + + T++++K+ + PP S+ P++
Sbjct: 2677 LEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGA-VGPPGSWGAEPSS 2726
Score = 35.8 bits (81), Expect = 0.25
Identities = 52/213 (24%), Positives = 74/213 (34%), Gaps = 28/213 (13%)
Query: 557 QPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPK--PSSQGFTNSTVAAPSARD 614
+P P PP PP P A + PM+ S P P + + G + P
Sbjct: 2186 EPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFL 2245
Query: 615 KPASSMSDDEMPVLEIPRKHQPSVPKAEEPL----------KTVQEKKKFRHRPEPLFIP 664
KP D+ L +P KA EPL K ++ KK+ P + P
Sbjct: 2246 KPRCPSLDN----LAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGP 2301
Query: 665 PPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLL--------LDPTHELPPYTPPPMLSP 716
P + +P+ SG L +L++P V L P L P PPP
Sbjct: 2302 PNLGFVDSPS---SGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPP-AQA 2357
Query: 717 VRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTP 749
+ ++ G + Q PLTP P
Sbjct: 2358 LAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP 2390
Score = 33.9 bits (76), Expect = 0.95
Identities = 39/150 (26%), Positives = 53/150 (35%), Gaps = 14/150 (9%)
Query: 187 QKPMEPPAPAIPSRYQQVPQQPH-----PGFTGGLSKPALQVGQHPTQGHLYYDYQQPLA 241
QK + A P++ QQ QQ H PG +S P G P+ LA
Sbjct: 3261 QKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLP--HEGSSPSLAGSQQQLSLGLA 3318
Query: 242 QVPVQG-GQPLQAPQMLSQHMQQMQQHQYYPPQQQ------QQAGQQRISMQEIQTQPQQ 294
G QPL Q + +QQ Q Q GQ + Q+
Sbjct: 3319 GARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLS 3378
Query: 295 IRPSQPQPPPQQQQPQQLQLQQRQGSMQIP 324
+P PP +PQQL +QQ+ + P
Sbjct: 3379 QKPMGTMPPSMCMKPQQLAMQQQLANSFFP 3408
Score = 30.8 bits (68), Expect = 8.1
Identities = 83/336 (24%), Positives = 114/336 (33%), Gaps = 44/336 (13%)
Query: 428 PPDTGMGDPASSDLTRVSSTLPHRPLLS-PSGIHLNNMG-PQHQQLSPSA-MWPQMHLPD 484
P + G PA + SS RP P H G P+HQ +P + P+ D
Sbjct: 2198 PYPSPTGAPAQPPMLGASS----RPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLD 2253
Query: 485 GRAQPGSPESSGQPKGA-------FGEQFDA----KNKLTCSICLKEFKNLPALNGHMRS 533
A P SP G FGE A K +L S NL ++ S
Sbjct: 2254 NLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSP--S 2311
Query: 534 HGGMRASPNLKQEEGEKV-LPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKL 592
G LK + K L P+ P P PQ PP A++L P P S P
Sbjct: 2312 SGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAP--SPPSHPDIF 2369
Query: 593 LPPKPSSQGFTNSTVAAP-SARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEK 651
P +T+ P + R +P S +P +P VP + + + Q
Sbjct: 2370 RP-----GSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSP 2424
Query: 652 KKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPP 711
R F P P + YS + Q R P P H+ P PP
Sbjct: 2425 LTPRPLSAEAFCPSPVTPRFQSPDPYSRPP-SRPQSRDP--------FAPLHKPPRPQPP 2475
Query: 712 PM------LSPVRQGSGLFSNVLISGHGPGAHPQLP 741
+ L+ G+G F L +G H ++P
Sbjct: 2476 EVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511
Score = 30.8 bits (68), Expect = 8.1
Identities = 22/97 (22%), Positives = 43/97 (44%), Gaps = 13/97 (13%)
Query: 260 HMQQMQQHQYYPPQQQ-------------QQAGQQRISMQEIQTQPQQIRPSQPQPPPQQ 306
H QQ+ Q Q ++Q +Q ++ + + ++++ Q Q
Sbjct: 3516 HTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQ 3575
Query: 307 QQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQ 343
+Q Q++ QQ++ + + +Y Q Q Q+QQQQQ
Sbjct: 3576 KQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQ 3612
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 84.0 bits (206), Expect = 8e-16
Identities = 144/592 (24%), Positives = 205/592 (34%), Gaps = 155/592 (26%)
Query: 167 HTQSAVMDGAPDSALR--------QLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSK 218
H+ + V P + L+ Q Q+ + A+ + QQ QQ + +
Sbjct: 139 HSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQ 198
Query: 219 PALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQA 278
V Q Q QQ L ++ Q Q +Q Q Q + Q+Q Q QQQQQ
Sbjct: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQ----QQQQQQ 254
Query: 279 GQQRISMQEIQTQP--QQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHL 336
QQ+ Q +Q QP QQ QPQPPP Q PQQLQ M Q++QP P Q
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQ------QMHHTQHHQPPPQPQ-- 306
Query: 337 QEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQ------YYYQEP-------- 382
QPP P Q P+ Q PL S +Q Y Q P
Sbjct: 307 ----------QPPVAQNQPSQLPPQS----QTQPLVSQAQALPGQMLYTQPPLKFVRAPM 352
Query: 383 --QQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLG---PPDTGMGDPA 437
QQP P QQ + Q + +Q+ +A+ + PP T +
Sbjct: 353 VVQQPPVQPQVQQQQTAV-QTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIP 411
Query: 438 SSDLTRVSSTLPHRPL--LSPSGI-HLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPES 494
SS S L +P+ +S S + L++ P Q +P +M P P QPG P S
Sbjct: 412 SS-----SIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPP---PQPSPQPGQPSS 463
Query: 495 SGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPP 554
PN G P
Sbjct: 464 ---------------------------------------------QPNSNVSSG-----P 473
Query: 555 QPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARD 614
P P P P P P Q P A TP V P L +T PS+
Sbjct: 474 APSPSSFLPSPSPQPSQSPVTAR--TPQNFSVPSPGPL------------NTPVNPSSVM 519
Query: 615 KPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTV-------QEKKKFRHRPEPLFIPPPP 667
PA S +E L+ ++ + K EPL+ + +++KK + + L
Sbjct: 520 SPAGSSQAEEQQYLDKLKQ----LSKYIEPLRRMINKIDKNEDRKKDLSKMKSLL----- 570
Query: 668 SYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQ 719
+P+ TL + ++ ++ D + P PPP + P +Q
Sbjct: 571 DILTDPSKRCPLKTLQKCEIALEKLKNDMAV--------PTPPPPPVPPTKQ 614
Score = 50.4 bits (119), Expect = 1e-05
Identities = 119/460 (25%), Positives = 158/460 (34%), Gaps = 120/460 (26%)
Query: 148 QVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQ 207
Q A L+ Q Q Q + P ++Q Q+P PP+ A+P + QQ+
Sbjct: 239 QRIAQLQLQQQQQQQQQQQQQQQQALQAQPP--IQQPPMQQPQPPPSQALPQQLQQM--- 293
Query: 208 PHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQH 267
H TQ H Q P Q QP A SQ
Sbjct: 294 ------------------HHTQHH----------QPPPQPQQPPVAQNQPSQ-------- 317
Query: 268 QYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP------QPPPQQQQPQQLQLQQRQGSM 321
PPQ Q Q + + Q P Q+ +QP P QQ P Q Q+QQ+Q ++
Sbjct: 318 --LPPQSQTQP-----LVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAV 370
Query: 322 QIPQYYQ-PQPMMQHLQEQ-QQQQMHLQ---PPSYHRDPHQYTPEQAHTVQLIPLGSMSQ 376
Q Q Q P +Q + E Q MH++ PP+ T A IPLG
Sbjct: 371 QTAQAAQMVAPGVQMITEALAQGGMHIRARFPPT--------TAVSAIPSSSIPLG---- 418
Query: 377 YYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTG--MG 434
+QP + Q S L SS Q + + PP G
Sbjct: 419 ------RQPMA-------------QVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG 459
Query: 435 DPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQ---MHLPDGRAQPGS 491
P+S + VSS P SPS L + PQ Q +A PQ + P P +
Sbjct: 460 QPSSQPNSNVSS----GPAPSPSSF-LPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVN 514
Query: 492 PESSGQPKG---AFGEQFDAKNKLTCSIC--LKEFKNLPALN-------GHMRSHGGMRA 539
P S P G A +Q+ K K L+ N N M+S +
Sbjct: 515 PSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILT 574
Query: 540 SPN--------LKQEEGEKVLPPQPQPPLPPPPPPPPPPQ 571
P+ K E + L P PPPPP PP Q
Sbjct: 575 DPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQ 614
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 78.2 bits (191), Expect = 4e-14
Identities = 77/269 (28%), Positives = 110/269 (40%), Gaps = 19/269 (7%)
Query: 175 GAPDSALRQLLSQKPMEPPAPAI--PSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHL 232
G +S + ++ P PA+ P ++ ++ PG L L+ P Q
Sbjct: 47 GGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPG-QRELQLQQLEQQPEPQQQPQ 105
Query: 233 YYDYQQP-----LAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQE 287
+ QQP L Q P Q GQ Q L Q Q HQ P+ Q QQ++ Q+
Sbjct: 106 HEQLQQPQPHLELQQQPQQDGQ--QQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQ 163
Query: 288 IQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQ--QQQMH 345
+Q Q Q+++ Q Q QQ Q QQ+ QQ Q Q+ + Q + LQ+QQ QQQ
Sbjct: 164 VQEQ-QRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQ 222
Query: 346 LQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPL--YQQSHLSQH---Q 400
LQ + + Q +Q + L G + Q Q+ Q L QQ+ L Q Q
Sbjct: 223 LQQQQFQQQQEQ-LQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQ 281
Query: 401 QREDSQLKTYSSDRQAQAMLSSHGDLGPP 429
Q+E Q + Q Q L PP
Sbjct: 282 QQEQLQQQQQQQLLQQQQEQLQQQQLQPP 310
Score = 74.7 bits (182), Expect = 5e-13
Identities = 72/246 (29%), Positives = 103/246 (41%), Gaps = 33/246 (13%)
Query: 203 QVPQQPHPGFTGGLSKPALQVGQH-----PTQGHLYYDYQQPLAQVPVQGGQPLQAPQML 257
Q+ Q+ H KP LQ+ P Q QQ Q+ Q Q Q Q
Sbjct: 132 QLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQ 191
Query: 258 SQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQ---------- 307
Q QQ+Q+ Q QQQ+Q QQ++ Q+ Q Q QQ + Q Q QQQ
Sbjct: 192 EQLQQQVQEQQLLQ-QQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQL 250
Query: 308 -----QPQQLQLQQR-----QGSMQIPQYYQPQPMMQHLQEQQ---QQQMHLQPPSYHRD 354
Q QQ QLQQ+ Q +Q Q Q +Q Q+QQ QQQ LQ
Sbjct: 251 QQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPP 310
Query: 355 PHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDR 414
P + E+ ++L+P+ S+ ++ +Q L +Q L + Q++ QLK +
Sbjct: 311 PLEPEEEEEVELELMPVDLGSEQELEQQRQ----ELERQQELERQQEQRQLQLKLQEELQ 366
Query: 415 QAQAML 420
Q + L
Sbjct: 367 QLEQQL 372
Score = 70.9 bits (172), Expect = 7e-12
Identities = 76/247 (30%), Positives = 105/247 (42%), Gaps = 40/247 (16%)
Query: 182 RQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLA 241
R+L Q+ + P P +++Q+ QQP +P L++ Q P Q D QQ L+
Sbjct: 87 RELQLQQLEQQPEPQQQPQHEQL-QQP---------QPHLELQQQPQQ-----DGQQQLS 131
Query: 242 QVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQ---QQQAGQQRISMQEIQTQPQQIRPS 298
Q+ + Q + Q L +Q M Q Q PQQ QQ+ QQ+ +Q Q Q QQ+
Sbjct: 132 QLQQEKHQSVHH-QELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQ 190
Query: 299 QPQPPPQ-------QQQPQQLQ----------LQQRQGSMQIPQYYQPQPMMQHLQEQQQ 341
Q Q Q QQQ +QLQ LQQ+Q Q Q Q Q ++ Q+ Q
Sbjct: 191 QEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQL 250
Query: 342 QQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQ 401
QQ LQ +QA Q + L Q Q+ QQ L QQ Q QQ
Sbjct: 251 QQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQ----LLQQQQEQLQQQQ 306
Query: 402 REDSQLK 408
+ L+
Sbjct: 307 LQPPPLE 313
Score = 50.1 bits (118), Expect = 1e-05
Identities = 56/218 (25%), Positives = 94/218 (43%), Gaps = 22/218 (10%)
Query: 147 TQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQ 206
TQ Q + Q + Q + Q + +QLL Q+ + + +Q+ Q
Sbjct: 179 TQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE-QLQQQQFQQQQEQLQQ 237
Query: 207 QPHPGFT---GGLSKPALQVGQHPTQGHLYYDYQQPLAQVPV----QGGQPLQAPQMLSQ 259
Q G L + LQ Q Q L Q L Q + + Q Q Q+L Q
Sbjct: 238 QQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQ 297
Query: 260 HMQQMQQHQYYPP----QQQQQAGQQRI-----SMQEIQTQPQQIRPSQPQPPPQQQQPQ 310
+Q+QQ Q PP +++++ + + S QE++ Q Q++ + Q +QQ+ +
Sbjct: 298 QQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELE--RQQELERQQEQR 355
Query: 311 QLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQP 348
QLQL+ ++ Q+ Q + Q Q EQQ+ Q+ L P
Sbjct: 356 QLQLKLQEELQQLEQQLEQQ---QQQLEQQEVQLELTP 390
Score = 46.2 bits (108), Expect = 2e-04
Identities = 58/223 (26%), Positives = 89/223 (39%), Gaps = 47/223 (21%)
Query: 153 QNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGF 212
+ L+ Q QVL Q + + +QLL Q+ + + + +Q+ QQ
Sbjct: 175 EQLQTQQAQEQQVLQQQEQLQQQVQE---QQLLQQQQEQLQQQQLLQQQEQLQQQQ---- 227
Query: 213 TGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPP 272
+ Q+ Q Q L Q L Q +Q Q Q+L Q Q+QQ
Sbjct: 228 ---FQQQQEQLQQQ--QQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQ 282
Query: 273 QQQQQAGQQRISMQEIQTQPQQIRPSQPQPPP-------------------------QQQ 307
Q+Q Q QQ+ Q +Q Q +Q++ Q QPPP QQ+
Sbjct: 283 QEQLQQQQQQ---QLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQR 339
Query: 308 QP----QQLQLQQRQGSMQIPQYYQPQPMMQHL---QEQQQQQ 343
Q Q+L+ QQ Q +Q+ + Q + Q L Q+Q +QQ
Sbjct: 340 QELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQ 382
Score = 34.3 bits (77), Expect = 0.73
Identities = 37/155 (23%), Positives = 63/155 (40%), Gaps = 18/155 (11%)
Query: 182 RQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLA 241
+QLL Q+ + + + +Q+ QQ + Q P + + L
Sbjct: 264 QQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELE 323
Query: 242 QVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQ 301
+PV G + Q L Q Q++++ Q QQ+Q+ Q ++ +E+Q QQ+ Q Q
Sbjct: 324 LMPVDLG----SEQELEQQRQELERQQELERQQEQRQLQLKLQ-EELQQLEQQLEQQQQQ 378
Query: 302 PPPQ-------------QQQPQQLQLQQRQGSMQI 323
Q QQQ QL+L Q +Q+
Sbjct: 379 LEQQEVQLELTPVELGAQQQEVQLELTPVQPELQL 413
Score = 30.8 bits (68), Expect = 8.1
Identities = 26/91 (28%), Positives = 34/91 (37%), Gaps = 19/91 (20%)
Query: 1020 CGAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGE 1079
CG FS L H RIH G +KP YC+ + S S + +
Sbjct: 518 CGKGFSQHSNLVTHQRIHTG---------------EKP--YACSYCAKRFSESSALVQHQ 560
Query: 1080 TDPTTIFP--CKECGKVFFKIKSRNAHMKTH 1108
T P C +CGK F + H +TH
Sbjct: 561 RTHTGERPYACGDCGKRFSVSSNLLRHRRTH 591
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 77.4 bits (189), Expect = 8e-14
Identities = 99/324 (30%), Positives = 133/324 (41%), Gaps = 54/324 (16%)
Query: 91 PGNHV--QLRGNLANSNMMWGAPAQAEPTDGYQYTYSQA----------SEIRTQKLTSG 138
PGN + ++RGNL M G Q+ T+S A ++I+ S
Sbjct: 300 PGNILPPEVRGNL----MAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSN 355
Query: 139 VLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIP 198
V H L + + +NL QVN+ Q +AV L SQ + P +
Sbjct: 356 VAHILQTLSA--PTKNLEQQVNHSQQGHTNANAV-----------LFSQVKVTPETHMLQ 402
Query: 199 SRYQ-QVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQML 257
+ Q Q QQ HP L Q+ Q L QQ ++Q P P Q P
Sbjct: 403 QQQQAQQQQQQHPV----LHLQPQQIMQ------LQQQQQQQISQQPY----PQQPPHPF 448
Query: 258 SQHMQQMQQ-HQYYPPQQQQQAGQQRISM-QEIQTQPQQIRPSQPQPPPQQQ--QPQQLQ 313
SQ QQ QQ H + QQQ Q QQ++ Q++ QQ++P Q Q QQQ Q QQ Q
Sbjct: 449 SQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQ 508
Query: 314 LQQRQ-GSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRD----PHQYTPEQAHTVQL 368
LQQ+Q +Q Q Q +Q+QQ Q+MH Q PH QA Q+
Sbjct: 509 LQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQV 568
Query: 369 IPLGSMSQYYYQE-PQQPYSHPLY 391
P Q Q+ P P H L+
Sbjct: 569 PPQQPPQQQQQQQPPPSPQQHQLF 592
Score = 77.4 bits (189), Expect = 8e-14
Identities = 73/226 (32%), Positives = 90/226 (39%), Gaps = 20/226 (8%)
Query: 142 KLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQK-PMEPPAPAIPSR 200
K+ T + Q Q VLH Q + +Q+ Q P +PP P +
Sbjct: 393 KVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQ 452
Query: 201 YQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQH 260
QQ PH L P Q+ HP Q +P Q+ QP Q L Q
Sbjct: 453 QQQQQAHPHQFSQQQLQFPQQQL--HPPQ-----QLHRPQQQL-----QPFQQQHALQQQ 500
Query: 261 MQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGS 320
Q+QQHQ QQQQ A Q+ Q Q QQI+ Q Q QQQQ QQ+Q Q
Sbjct: 501 FHQLQQHQL---QQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHL 557
Query: 321 MQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHR----DPHQYTPEQ 362
Q Q Q Q Q +QQQQQ P H+ DP PE+
Sbjct: 558 SQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEIPEE 603
Score = 71.6 bits (174), Expect = 4e-12
Identities = 62/181 (34%), Positives = 76/181 (41%), Gaps = 13/181 (7%)
Query: 256 MLSQHMQQMQQHQYYP-----PQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQ 310
ML Q Q QQ Q +P PQQ Q QQ+ Q+I QP P QP P QQQ Q
Sbjct: 400 MLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQ--QQQISQQPY---PQQPPHPFSQQQQQ 454
Query: 311 QLQLQQRQGSMQIPQYYQPQ--PMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQL 368
Q Q Q S Q Q+ Q Q P Q + QQQ Q Q + + HQ Q QL
Sbjct: 455 QQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQL 514
Query: 369 IPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGP 428
L Q+ QQ Q+ H Q QQ+ SQ + S + +QA+ P
Sbjct: 515 AQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLS-QTSQALQHQVPPQQP 573
Query: 429 P 429
P
Sbjct: 574 P 574
Score = 53.5 bits (127), Expect = 1e-06
Identities = 63/234 (26%), Positives = 86/234 (36%), Gaps = 22/234 (9%)
Query: 280 QQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQ 339
QQ Q+ T + SQ + P+ QQ Q Q+Q + QPQ +MQ Q+Q
Sbjct: 372 QQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQ 431
Query: 340 QQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQH 399
QQQ Q P + PH ++ +Q Q P SQ Q PQQ P QQ H Q
Sbjct: 432 QQQIS--QQPYPQQPPHPFSQQQQQQQQAHP-HQFSQQQLQFPQQQLHPP--QQLHRPQQ 486
Query: 400 Q----------QREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLP 449
Q Q++ QL+ + +Q A L L L R+
Sbjct: 487 QLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSL-LQQQQQQQIQQQQLQRMHQQQQ 545
Query: 450 HRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFG 503
+ + S + HL+ Q P PQ + Q P S Q FG
Sbjct: 546 QQQMQSQTAPHLSQTSQALQHQVPPQQPPQ------QQQQQQPPPSPQQHQLFG 593
Score = 32.3 bits (72), Expect = 2.8
Identities = 16/32 (50%), Positives = 20/32 (62%)
Query: 956 EEEEELEEEEEEDPEEDRKSTKEEESEVPKSP 987
EEEEE EEEEEE E++ S E ++ SP
Sbjct: 189 EEEEEEEEEEEEVENEEQDSQNEGSTDEKSSP 220
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 76.3 bits (186), Expect = 2e-13
Identities = 142/629 (22%), Positives = 196/629 (31%), Gaps = 127/629 (20%)
Query: 184 LLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQV 243
L + P+ PP+P+ P Q +P S PA Q P P Q
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLP-----------SPPATPPSQAPPS------MTTPPMQA 379
Query: 244 P--VQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQ---------QAGQQRISMQEIQTQP 292
P +Q P+Q P L+ Q Q QA ++M QTQ
Sbjct: 380 PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQA 439
Query: 293 QQIRPSQPQPPPQQQQPQQ-------------------------LQLQQRQGSMQIPQYY 327
PS+P P P Q L + Q + +
Sbjct: 440 SLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
Query: 328 QPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYS 387
P+ + + Q L PPS P T T L L S++ Q P +
Sbjct: 500 PQAPLSSLIMPPLETQSSLAPPSLQTPPASLT-----TPPLENLPSLAPPPLQTASAPLT 554
Query: 388 HPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSST 447
P HL L+ S + PP AS L + S
Sbjct: 555 TP-----HLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609
Query: 448 LPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSG-QPKGAFGEQF 506
P PL +P P P + LP +A P P S P Q
Sbjct: 610 -PLSPLATP----------------PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ- 651
Query: 507 DAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEG--EKVLPPQPQPPLPPPP 564
A N L + F P + +++ ASP + + P PPL PP
Sbjct: 652 -APNALAVHLLQAPFS--PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 708
Query: 565 PPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDE 624
PP P + P A P++ P +PP P + S +PSA P
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA-----SPPMSPSATPPPRVP----- 758
Query: 625 MPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQ 684
P+L P P P A P+ + + + P PP P+P AS+ G +
Sbjct: 759 -PLLAAPPLQVPPSPPASLPMSPLAKPPP---QAPPALATPPLQALPSPPASFPGQAPFS 814
Query: 685 SQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHP--QLPL 742
P + P PP PP + +P+ Q P A P Q P
Sbjct: 815 PSASLP--------MSPLATPPPQAPPVLAAPLLQ----------VPPSPPASPTLQAPR 856
Query: 743 TPLTPTPRVLLCRSNSIDGSNVTVTPGPG 771
P TP P S+ G +T+ PG
Sbjct: 857 RPPTPGP------DTSVSGPRLTLALAPG 879
Score = 68.2 bits (165), Expect = 5e-11
Identities = 139/609 (22%), Positives = 193/609 (31%), Gaps = 98/609 (16%)
Query: 189 PMEPPAPAIPSRYQQVPQQPHPGFT------GGLSKPALQVGQHPTQGHLYYDYQQPLAQ 242
P E P ++ S + +P P GGL +PA + + P
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR-----SLSSSATPLSSPARS 255
Query: 243 VPVQGGQPLQAPQMLSQH----MQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPS 298
P G P +AP SQ +Q ++ Q PP++ +S + T +
Sbjct: 256 GPSARGTP-RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKA 314
Query: 299 QPQPPPQQQQPQQLQLQQRQGSMQIPQYYQP-----QPMMQHLQEQQQQQMHLQPPSYHR 353
+P PPP + P P P +Q L PPS
Sbjct: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT 374
Query: 354 DPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSD 413
P Q P + S++ Q P P + Q + + + S
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434
Query: 414 RQAQAMLSSHG-------DLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGP 466
RQ QA L+S D P + PAS L + S + PL SP IH
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL-QTSLSPAVSPLSSPLTIHPLQALS 493
Query: 467 QHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPA 526
SP A + +P Q S Q A S+ +NLP+
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA-------------SLTTPPLENLPS 540
Query: 527 LNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPP----PPPPPPPQLPPEAESLTPM 582
L A P L+ P PP P P PP P PPE S
Sbjct: 541 L-----------APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT 589
Query: 583 VMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAE 642
P + P PP QG PS P ++ P L +P P P A
Sbjct: 590 PPPQAPPALASPP---LQGL-------PSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
Query: 643 EPLKTVQEKKKFR------HRPEPLFIPPP---------PSYNP--NPAA---SYSGATL 682
PL + H + F PPP P +P +P+A S + +L
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699
Query: 683 YQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPL 742
L+ P + P+ PP PPP+ +P Q + P + P P
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ---------VPPSPPASPPMSP- 749
Query: 743 TPLTPTPRV 751
TP PRV
Sbjct: 750 -SATPPPRV 757
Score = 33.5 bits (75), Expect = 1.2
Identities = 50/205 (24%), Positives = 66/205 (32%), Gaps = 26/205 (12%)
Query: 170 SAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQ 229
S + G P L L + P PP A+P Q P P P + LS A Q P
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPP--LQAP--PSPPASPPLSPLATPSPQAPNA 655
Query: 230 GHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQ 289
++ Q P + P P+QAP S PP Q + +
Sbjct: 656 LAVHL-LQAPFSPPP---SPPVQAP--FSPPASPPVSPSATPPSQ---------APPSLA 700
Query: 290 TQPQQIRPSQPQPPPQQQQ---PQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHL 346
P Q+ PS P PP P Q +Q+P P P
Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP----PSPPASPPMSPSATPPPR 756
Query: 347 QPPSYHRDPHQYTPEQAHTVQLIPL 371
PP P Q P ++ + PL
Sbjct: 757 VPPLLAAPPLQVPPSPPASLPMSPL 781
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 74.3 bits (181), Expect = 6e-13
Identities = 104/390 (26%), Positives = 137/390 (35%), Gaps = 61/390 (15%)
Query: 86 GSHAGPGNHVQLRG-------NLANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSG 138
G GP QLR ++ANS + +P + P SQA + SG
Sbjct: 371 GLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQ-------SQAQP----QTGSG 419
Query: 139 VLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPD--SALRQLLSQKP-----ME 191
L S+ +V Q L+ N Q Q P SAL P +
Sbjct: 420 ASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEK 479
Query: 192 PPAPAIPSRYQQVPQQPHPGFTGGLSKPAL------QVGQHPTQGHLYYDYQQP---LAQ 242
P+P+ + P PG GG + + + G GHL QQ L++
Sbjct: 480 IPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSR 539
Query: 243 VPVQGGQPLQAPQMLSQ----HMQQMQQHQYYPP--------------QQQQQAGQQRIS 284
+ P P+ + H Q +Q P QQQQQ QQ+
Sbjct: 540 SFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQ 599
Query: 285 MQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQM 344
Q+ Q Q QQ + Q Q QQ Q QQ+Q S+ Q Q Q Q Q+QQQQQ
Sbjct: 600 QQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQ 659
Query: 345 HLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQRED 404
Q P Q P Q +PL Q QP + YQ S QQR+D
Sbjct: 660 QQQQQQPSSQPAQSLPSQPLLRSPLPL-QQKLLLQQMQNQPIAGMGYQVS----QQQRQD 714
Query: 405 SQLKTYSSDRQAQAMLSSHGDLGPPDTGMG 434
+S Q S P+TG G
Sbjct: 715 Q----HSVVGQNTGPSPSPNPCSNPNTGSG 740
Score = 40.0 bits (92), Expect = 0.013
Identities = 74/304 (24%), Positives = 103/304 (33%), Gaps = 21/304 (6%)
Query: 54 SPHFPQDTRDGLGLPVGSKNLGQMDTSRQGGWGSHAGP---GNHV-----QLRGNLANSN 105
SP F Q T P+ G + + AGP G H+ Q +L+ S
Sbjct: 482 SPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSF 541
Query: 106 MMWGAPAQAEPTDG-----YQYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVN 160
+ PA EP G + + QA++ L S L +TQ Q + Q
Sbjct: 542 INNPHPAM-EPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQ 600
Query: 161 NMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPA 220
Q Q + +Q+ + + +I ++ QQ QQ +
Sbjct: 601 QQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQS-SISAQQQQQQQQQQQQQQQQQQQQQ 659
Query: 221 LQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQ 280
Q Q P+ QPL + P+ PLQ +L Q Q Y QQQ+ Q
Sbjct: 660 QQQQQQPSSQPAQSLPSQPLLRSPL----PLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQ 715
Query: 281 QRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQ 340
+ Q P S P QQ L Q+ M Q Q Q M Q Q
Sbjct: 716 HSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQ--LMGKKQTLQRQIMEQKQQLLL 773
Query: 341 QQQM 344
QQQM
Sbjct: 774 QQQM 777
Score = 30.8 bits (68), Expect = 8.1
Identities = 38/161 (23%), Positives = 61/161 (37%), Gaps = 44/161 (27%)
Query: 182 RQLLSQKPMEPPAPAIPSR--------------YQQVPQQPHPGFTGGLSKPALQ----- 222
+Q Q+P PA ++PS+ QQ+ QP G +S+ Q
Sbjct: 659 QQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSV 718
Query: 223 VGQH------------PTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYY 270
VGQ+ P G Y + QQ L + G + Q++ Q Q + Q
Sbjct: 719 VGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQ---- 774
Query: 271 PPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQ 311
QQ A ++I+ Q+ QI +PPP + ++
Sbjct: 775 ---QQMLADAEKIAPQD------QINRHLSRPPPDYKDQRR 806
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 73.9 bits (180), Expect = 8e-13
Identities = 69/214 (32%), Positives = 86/214 (40%), Gaps = 43/214 (20%)
Query: 187 QKPMEPPAPAIPSRYQQVP-QQPHPGFTGGLSKPALQVGQHP---------TQGHLYYDY 236
Q+ P +P Y P Q HP L P + Q P T GH
Sbjct: 1954 QQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTST 2013
Query: 237 Q----QPLAQVPV---------QGGQP-LQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQR 282
Q Q L Q P+ QG Q +++ +L + QQ QQ Q QQQQQ QQ+
Sbjct: 2014 QRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQ 2073
Query: 283 ISMQEIQTQPQQ--IRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQ 340
I+ Q QQ +R Q Q QQQQ QQ Q QQ+ Q QH Q+QQ
Sbjct: 2074 QQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQ------------QQQQQHQQQQQ 2121
Query: 341 QQQMHLQP-----PSYHRDPHQYTPEQAHTVQLI 369
QQ QP P + R Q T +Q T L+
Sbjct: 2122 QQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALV 2155
Score = 65.1 bits (157), Expect = 4e-10
Identities = 87/301 (28%), Positives = 112/301 (37%), Gaps = 63/301 (20%)
Query: 168 TQSAVMDGAPDSALRQLLSQKPMEPPAPAIPS--RYQQVPQQPHPGFTGGLS----KPAL 221
T + VM P S + Q+ PA+P R +Q QQ G G S P+
Sbjct: 1881 TMTGVMGLEPSSYKTSVYRQQQ-----PAVPQGQRLRQQLQQSQ-GMLGQSSVHQMTPSS 1934
Query: 222 QVGQHPTQGHLYYDYQQPLAQ---------------VPVQGGQPLQAPQML--SQHMQQM 264
G +QG+ Y L Q P Q P P ++ ++H+QQ
Sbjct: 1935 SYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQR 1994
Query: 265 QQ---HQYYPPQQQQQAGQQRISMQEIQTQPQ--QIRPSQPQP-----------PPQQQQ 308
HQ P QR S Q +Q P + P Q P QQQQ
Sbjct: 1995 PSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQ 2054
Query: 309 PQQLQLQQRQGSMQIPQYYQ------PQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQ 362
QQ Q QQ+Q Q Q Q Q Q L++QQQQQ Q + Q +Q
Sbjct: 2055 QQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQ 2114
Query: 363 AHTVQLIPLGSMSQYYYQEPQ-QPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLS 421
H Q Q PQ QP S P +Q+ L Q QQ Q +T + RQ Q LS
Sbjct: 2115 QHQQQ-------QQQQAAPPQPQPQSQPQFQRQGLQQTQQ----QQQTAALVRQLQQQLS 2163
Query: 422 S 422
+
Sbjct: 2164 N 2164
Score = 39.3 bits (90), Expect = 0.023
Identities = 87/447 (19%), Positives = 145/447 (32%), Gaps = 57/447 (12%)
Query: 191 EPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQP 250
EPPAP + ++ P+ P G + + T+G QP + G P
Sbjct: 1750 EPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGK---KRSQPATKTEDYGMGP 1806
Query: 251 -------LQAPQMLSQH-----MQQMQQHQ----YYPPQQQQQAGQQRISMQEIQTQPQQ 294
+ P L H + + Q Y Q AG R+ P Q
Sbjct: 1807 GRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQ 1866
Query: 295 IRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRD 354
P++P P + S + Y Q QP + Q +QQ Q
Sbjct: 1867 KLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSS 1926
Query: 355 PHQYTPEQAHTVQLIP--LGSMSQYYYQEPQQP--------YSHPLYQQSHLSQHQQRED 404
HQ TP ++ +Q +S Q+ P YS YQ +H S + D
Sbjct: 1927 VHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVD 1986
Query: 405 SQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNM 464
R Q S + P G G ++ + TL P++S + M
Sbjct: 1987 PT-------RHLQQRPSGYVHQQAPTYGHGLTSTQRFSH--QTLQQTPMIST----MTPM 2033
Query: 465 GPQHQQ--LSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFK 522
Q Q + +A+ P+ + Q + Q + +Q+ + + I ++ +
Sbjct: 2034 SAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQ 2093
Query: 523 NLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPM 582
+ + +Q++ ++ Q Q PP P P PQ + T
Sbjct: 2094 Q------QQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQ 2147
Query: 583 VMPVSVPVKLL-------PPKPSSQGF 602
+ V+ L P+PS+ F
Sbjct: 2148 QQQTAALVRQLQQQLSNTQPQPSTNIF 2174
Score = 33.5 bits (75), Expect = 1.2
Identities = 40/189 (21%), Positives = 74/189 (39%), Gaps = 23/189 (12%)
Query: 585 PVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEP 644
PV +P++ LP +P+ G +T+ + + S + R+ QP+VP+ +
Sbjct: 1860 PVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTS--------VYRQQQPAVPQGQRL 1911
Query: 645 LKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGD-HLLLDPTH 703
+ +Q+ + + + P SY + Y T Y S + + G ++ P++
Sbjct: 1912 RQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGY---TPYVSHVGLQQHTGPAGTMVPPSY 1968
Query: 704 ELPPY------TPPPMLSPVR----QGSG-LFSNVLISGHGPGAHPQLPLTPLTPTPRVL 752
PY T P ++ P R + SG + GHG + + L TP +
Sbjct: 1969 SSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMIS 2028
Query: 753 LCRSNSIDG 761
S G
Sbjct: 2029 TMTPMSAQG 2037
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 70.5 bits (171), Expect = 9e-12
Identities = 105/447 (23%), Positives = 161/447 (36%), Gaps = 67/447 (14%)
Query: 157 IQVNNMAQVL-----HTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPG 211
I++NN A V+ + S++M P+ L+ + + A + QQ HP
Sbjct: 174 IRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHP- 232
Query: 212 FTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYP 271
+G L+ P HP Q + + Q A P Q Q Q QQ QQ Q
Sbjct: 233 -SGSLAPP-----HHPMQP-VSVNRQMNPANFP-------QLQQQQQQQQQQQQQQQQQQ 278
Query: 272 PQQQQQAGQQRISMQEIQTQPQQIRP------SQPQPPPQQQQP----QQLQLQQRQGSM 321
QQQQQ Q R Q Q QPQ IRP P PP Q P Q Q G+M
Sbjct: 279 QQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTM 338
Query: 322 QIPQYYQPQPMMQHLQEQQQQQMHL---QPPSYHRDPHQYTPE---QAHTVQLIPLGSMS 375
Q ++ P+ +Q+Q Q + L Q PS+ P+ + + QAHT + +
Sbjct: 339 TANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHT-NFPQMSNPG 397
Query: 376 QYYYQEPQQPYSHPL-----YQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPD 430
Q+ + + P QQ HL+ S + + + +GP
Sbjct: 398 QFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRP 457
Query: 431 TGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQ--QLSPSAMWPQMHLPDGRAQ 488
+P + S+ P++ + N M Q Q P ++ P + R
Sbjct: 458 P-QNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLP 516
Query: 489 PGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGG---MRASPNLKQ 545
PG P G+ +P+ + G ++A+ N++
Sbjct: 517 PGFSAGQANPNFMQGQ-------------------VPSTTATTPGNSGAPQLQANQNVQH 557
Query: 546 EEGEKVLPPQPQPPLPPPPPPPPPPQL 572
G+ PPQ Q + PP P L
Sbjct: 558 AGGQGAGPPQNQMQVSHGPPNMMQPSL 584
Score = 70.1 bits (170), Expect = 1e-11
Identities = 172/838 (20%), Positives = 267/838 (31%), Gaps = 162/838 (19%)
Query: 47 APQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPG---NHVQLRGNLAN 103
AP P+ P + Q L P +LG M ++ GW PG +Q R +LA
Sbjct: 308 APTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQ--GWKKAPLPGPMQQQLQARPSLAT 365
Query: 104 SNMMWGAPAQAEPTDGYQYTYSQASEIRTQ--------KLTSGVLHKLDSFTQVFANQNL 155
+ P Y + QAS+ T + T+ + L
Sbjct: 366 ------VQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQ 419
Query: 156 RIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPA------------------- 196
+ + N + + S+ G+P S+ +Q+ M P P
Sbjct: 420 QPHLTNKSPA-SSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNP 478
Query: 197 ------IPSRYQQVPQQPH-------------------PGFTGGLSKPALQVGQHP---- 227
+P + + QQP PGF+ G + P GQ P
Sbjct: 479 MVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTA 538
Query: 228 -TQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQ------HMQQ---MQQHQYYPPQQQQQ 277
T G+ Q V GGQ PQ Q +M Q M H QQ
Sbjct: 539 TTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGT 598
Query: 278 AGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPM-MQHL 336
+G ++++ +Q QPQQ PSQ QQ P Q Q+ Q+QG++ PQ PM +
Sbjct: 599 SGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLN-PQ----NPMILSRA 653
Query: 337 QEQQQQQMHLQPPSYH--RDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQS 394
Q Q QM + PPS + P + TP + L G + + P L QQ+
Sbjct: 654 QLMPQGQMMVNPPSQNLGPSPQRMTPPKQ---MLSQQGPQMMAPHNQMMGPQGQVLLQQN 710
Query: 395 HLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLL 454
+ + Q + Q Q+ + GP G + V T +
Sbjct: 711 PMIEQIMTNQMQGNKQQFNTQNQSNVMP----GPAQIMRGPTPNMQGNMVQFTGQMSGQM 766
Query: 455 SPSGIHLNN-----MGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAK 509
P +NN MG Q Q L P P H+ P + ++ +
Sbjct: 767 LPQQGPVNNSPSQVMGIQGQVLRPPG--PSPHMAQQHGDPATTANNDVSLSQMMPDVSIQ 824
Query: 510 NKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLP-------- 561
++ + A H HG +P G ++ Q P P
Sbjct: 825 QTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQ-NPGFPVNKDVTLT 883
Query: 562 ------------------------------PPPPPPPPPQLPPEAESLTPMVMPVSVPVK 591
P PP + + + TP P +
Sbjct: 884 SPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEA 943
Query: 592 LLPPKPSSQGFT--NSTVAAPSARDKPAS--SMSDDEMPVLEIPRK-----HQPSVPKAE 642
PP P QG NS P ++P S ++ P+ ++P + P P +
Sbjct: 944 DQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQ 1003
Query: 643 EPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPT 702
+P + ++++ PPPPS + + + L +
Sbjct: 1004 QPQPQLPQQQQ----------PPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQN 1053
Query: 703 HELP--PYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNS 758
P P P P++Q + V++S GP + P P P P SNS
Sbjct: 1054 VHPPRGPLNPDSQRMPMQQSGSV--PVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNS 1109
Score = 69.7 bits (169), Expect = 2e-11
Identities = 164/746 (21%), Positives = 242/746 (32%), Gaps = 108/746 (14%)
Query: 166 LHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPA----L 221
++ Q A G P L + Q PP+ + Q VP Q G P L
Sbjct: 591 MNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMIL 650
Query: 222 QVGQHPTQGHLYYDYQQ------PLAQVPVQGGQPLQAPQMLSQHMQQMQQH-----QYY 270
Q QG + + P P + Q PQM++ H Q M Q
Sbjct: 651 SRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQN 710
Query: 271 PPQQQQQAGQQRISMQEIQTQPQQ-IRPSQPQ---PPPQQQQPQQLQLQQRQGSMQIPQY 326
P +Q Q + + Q+ TQ Q + P Q P Q +Q + +PQ
Sbjct: 711 PMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQ 770
Query: 327 YQPQPMMQHLQEQQQQQMHLQPPS-----YHRDPHQYTPEQAHTVQLIPLGSMSQYYYQE 381
+ Q Q + PS H DP Q++P S+ Q
Sbjct: 771 GPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVP 830
Query: 382 PQ-QPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSD 440
P Q +H S H ++ + Q G P + D
Sbjct: 831 PHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSC-----------GQNPGFPVNKD 879
Query: 441 LTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGR------------AQ 488
+T S L + L S I + G ++Q + +A P+ P + +
Sbjct: 880 VTLTSPLLVN---LLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTR 936
Query: 489 PGSPESSGQPK--GAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQE 546
P E + QP G G D L EF N P G+ R + +
Sbjct: 937 PAGLEEADQPPLPGEQGINLDNSGPK-----LPEFSNRPP--GYPSQPVEQRPLQQMPPQ 989
Query: 547 EGEKVLPP------QPQPPLPPP--PPPPPPPQLPPEAESLTPMVMPVSV---PVKLLPP 595
+ V PP QPQP LP PPPP PQ + + M+M + + P + P
Sbjct: 990 LMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLP 1049
Query: 596 KPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPK------AEEPLKTVQ 649
+ + S R S S M L+ P PS K PL +
Sbjct: 1050 VSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNS 1109
Query: 650 EKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYT 709
K ++ P+ P P AS S A S P + H++L P ++L
Sbjct: 1110 RKMVYQESPQNPSSSPLAEMASLPEASGSEA---PSVPGGPNNMPSHVVL-PQNQLMMTG 1165
Query: 710 PPPMLSPVRQGSGLFS-----NVLISGHGPG----AHPQLPLTPLTPT--------PRVL 752
P P SP+ G N L S HG A P P TP P+
Sbjct: 1166 PKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTP 1225
Query: 753 LCRSNSIDGSNVTVTPG----------PGEQTVDVEPRINIGLRFQAEIPELQDISALAQ 802
R S + S ++++P P + + + PR N+ F + + A+ Q
Sbjct: 1226 NNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQ 1285
Query: 803 DTHKATLVWKPWPELENHDLQQRVEN 828
T+ + + H L V N
Sbjct: 1286 APSNLTMNPSNFATPQTHKLDSVVVN 1311
Score = 65.9 bits (159), Expect = 2e-10
Identities = 194/836 (23%), Positives = 279/836 (33%), Gaps = 160/836 (19%)
Query: 54 SPHFPQDTRDGLGLPVGSKNLGQM--DTSRQGGWGSHAGPGNHVQLRGNLANSN------ 105
SPH Q D +L QM D S Q ++ P + ++GN A+ N
Sbjct: 794 SPHMAQQHGDPATTANNDVSLSQMMPDVSIQQ---TNMVPPHVQAMQGNSASGNHFSGHG 850
Query: 106 MMWGAPAQAEPTDGYQYTYSQASEIRTQK---LTSGVLHKLDSFTQVFANQNLRIQVNNM 162
M + AP P +G Q + Q K LTS +L L + + A VNN
Sbjct: 851 MSFNAPFSGAP-NGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQ-SDISAGH---FGVNNK 905
Query: 163 AQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTG---GLSKP 219
+ P ++ SQ+ + P P+ ++ Q P PG G S P
Sbjct: 906 QNNTNANKPKKKKPPR---KKKNSQQDLNTPDTR-PAGLEEADQPPLPGEQGINLDNSGP 961
Query: 220 ALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAG 279
L + G+ QP+ Q P+Q P Q+ QH PPQ QQ
Sbjct: 962 KLPEFSNRPPGYP----SQPVEQRPLQQMPP------------QLMQHVAPPPQPPQQ-- 1003
Query: 280 QQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQ 339
QPQ P Q QPPP QPQ Q QQ+Q M + Q P L
Sbjct: 1004 -----------QPQPQLPQQQQPPP-PSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVS 1051
Query: 340 QQQQMHLQP--PSYHRDPHQYTPEQAHTVQL--------------------IPLGSMSQ- 376
Q P P R P Q + V L PLGS S+
Sbjct: 1052 QNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRK 1111
Query: 377 -YYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDL--GPPDTGM 433
Y + PQ P S PL + + L + E + ++ + +L + + GP
Sbjct: 1112 MVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGP----- 1166
Query: 434 GDPASSDLTRVSSTLPHRP----LLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQP 489
P S L+ P +P L S G H N+ Q P P P
Sbjct: 1167 -KPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTP 1225
Query: 490 GSPESSGQPKGAFGEQFDAKNKLTCSIC--LKEFKNLPALNGHMRSHGGMRASPNLKQEE 547
+ S +P E + +L SI N+P + PNL +
Sbjct: 1226 NNRPPSTEP----SEISLSPERLNASIAGLFPPQINIP-----------LPPRPNLNRGF 1270
Query: 548 GEKVLPPQPQPPLPPPP---PPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTN 604
++ L P + P P P+ L +V+ K S+ G T
Sbjct: 1271 DQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSG--------KQSNSGATK 1322
Query: 605 STVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEP----LKTVQEKKKFRHRPEP 660
+ S R P SS P + P + A + L+ V+ + P P
Sbjct: 1323 RASPSNSRRSSPGSSRKTTPSPGRQ--NSKAPKLTLASQTNAALLQNVELPRNVLVSPTP 1380
Query: 661 LFIPPPPSYNPN-----------PAASYSG--------------ATLYQSQLRSPRVLGD 695
L PP P PN A+ G + SQ R +V
Sbjct: 1381 LANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQV-NI 1439
Query: 696 HLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCR 755
L P E+ P + G N L S + L + P L
Sbjct: 1440 ELKAVPAQEVKMVVPEDQSK--KDGQPSDPNKLPSVE---ENKNLVSPAMREAPTSLSQL 1494
Query: 756 SNSIDGSNVTVTPGPGEQTVDVEPRINIG--LRFQAEIPELQDISALAQDTHKATL 809
++ NVT+ P PG ++V P + G L+ + IP LQD+S+ + ++ L
Sbjct: 1495 LDNSGAPNVTIKP-PGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNL 1549
Score = 32.7 bits (73), Expect = 2.1
Identities = 54/212 (25%), Positives = 73/212 (34%), Gaps = 45/212 (21%)
Query: 467 QHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPA 526
QHQQ P + PQ P P P + P GA + A+ L + +K P
Sbjct: 293 QHQQQQPQGIRPQFTAPT--QVPVPPGWNQLPSGAL-QPPPAQGSLGTMTANQGWKKAP- 348
Query: 527 LNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPV 586
L G M+ ++A P+L Q P PPPP P Q +A + P +
Sbjct: 349 LPGPMQQQ--LQARPSLATV----------QTPSHPPPPYPFGSQQASQAHTNFPQ---M 393
Query: 587 SVPVKLLPPKPSSQGFTNSTVAAP-----SARDKPASSMSDDEMPVLEIPRKHQPSVPKA 641
S P + P+ S S V P PASS P Q P +
Sbjct: 394 SNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASS-----------PSSFQQGSPAS 442
Query: 642 EEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNP 673
+ Q++ P PP NP P
Sbjct: 443 SPTVNQTQQQMG----------PRPPQNNPLP 464
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 69.7 bits (169), Expect = 2e-11
Identities = 98/395 (24%), Positives = 145/395 (36%), Gaps = 75/395 (18%)
Query: 252 QAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPS-------QPQPPP 304
Q P ++S Q H P Q Q Q + Q QPQ + P+ P+
Sbjct: 1629 QTPDLISA---QPAHHPPQSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALL 1685
Query: 305 QQQQPQ----------QLQLQQRQGSMQIPQYYQPQ------PMMQHLQEQQQQQMHLQP 348
Q QQPQ + L G + P +++ L++Q Q Q H+
Sbjct: 1686 QFQQPQFLFPFYIPGTEFSLGPDLGLPGSATFGMPGMTGMAGSLLEDLKQQIQTQHHVGQ 1745
Query: 349 PSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLK 408
Q QA QL P ++ QQP QQ S+ ++E S +
Sbjct: 1746 TQLQILQQQAQQYQATQPQLQP--------QKQQQQPPPPQQQQQQQASKLLKQEQSNI- 1796
Query: 409 TYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQH 468
S+D Q + S+ + + D++ + G+ +
Sbjct: 1797 -VSADCQIMKDVPSYKE------------AEDISEKPEKPKQEFISEGEGLKEGKDTKKQ 1843
Query: 469 QQLSPSAMWPQMHL-PDGRAQPGSPESSG--------------QPKGAFGEQFDAKNKLT 513
+ L PS P++ G A E+ G Q KG GE + +KL
Sbjct: 1844 KSLEPSIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKSGEG-ENTDKLE 1902
Query: 514 CSICLKEFKNLPALNGHMRS-HGGMRASPNLKQ------EEGEKVLPPQPQPPL--PPPP 564
C C K F N+ L H HG L++ E +K+ P P P PPPP
Sbjct: 1903 CGTCGKLFSNVLILKSHQEHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPPPPP 1962
Query: 565 PPPPPPQLPPEAESLTPMVMP--VSVPVKLLPPKP 597
PPPP P PP+ S+ P+ +P VS P++ PP P
Sbjct: 1963 PPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTP 1997
Score = 53.9 bits (128), Expect = 9e-07
Identities = 22/42 (52%), Positives = 27/42 (64%), Gaps = 6/42 (14%)
Query: 553 PPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLP 594
PP P PP PPPPPPPPPP PP+ + +PVS+ + L P
Sbjct: 1999 PPPPPPPPPPPPPPPPPPSAPPQVQ------LPVSLDLPLFP 2034
Score = 42.4 bits (98), Expect = 0.003
Identities = 32/110 (29%), Positives = 52/110 (47%), Gaps = 19/110 (17%)
Query: 248 GQPLQAPQMLSQHMQQMQQHQYYPPQQ----QQQAGQQRISMQEIQTQPQQIRPSQPQPP 303
G A +L QQ+Q + Q QQQA Q + + ++Q Q QQ +P PP
Sbjct: 1721 GMTGMAGSLLEDLKQQIQTQHHVGQTQLQILQQQAQQYQATQPQLQPQKQQQQP----PP 1776
Query: 304 PQQQQPQQLQ--LQQRQGSM---------QIPQYYQPQPMMQHLQEQQQQ 342
PQQQQ QQ L+Q Q ++ +P Y + + + + ++ +Q+
Sbjct: 1777 PQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISEKPEKPKQE 1826
Score = 36.6 bits (83), Expect = 0.15
Identities = 18/45 (40%), Positives = 20/45 (44%)
Query: 536 GMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLT 580
GM P L P PL PPPPPPP PP + SL+
Sbjct: 3089 GMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLS 3133
Score = 32.7 bits (73), Expect = 2.1
Identities = 29/77 (37%), Positives = 34/77 (44%), Gaps = 8/77 (10%)
Query: 211 GFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYY 270
G G L + Q Q TQ H+ Q Q+ Q Q QA Q Q Q QQ Q
Sbjct: 1724 GMAGSLLEDLKQ--QIQTQHHV----GQTQLQILQQQAQQYQATQ--PQLQPQKQQQQPP 1775
Query: 271 PPQQQQQAGQQRISMQE 287
PPQQQQQ ++ QE
Sbjct: 1776 PPQQQQQQQASKLLKQE 1792
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 69.3 bits (168), Expect = 2e-11
Identities = 133/535 (24%), Positives = 189/535 (35%), Gaps = 99/535 (18%)
Query: 247 GGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIR--PSQP---Q 301
GGQPL S M QM + + P QQ Q + PQQ P QP Q
Sbjct: 370 GGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQ----QGPPSGPQQGHGYPGQPYGSQ 425
Query: 302 PPPQQQQPQQLQLQQRQGSM----QIPQYYQPQPMMQHLQEQ----QQQQMH--LQPPSY 351
P + Q + Q G + QIP Y Q P Q Q QQ H Q P Y
Sbjct: 426 TPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPY 485
Query: 352 HRDPHQYTPEQAHTVQLIPLGSMSQYYYQEP---QQPYSHPLYQQSHLSQHQQREDSQLK 408
+ P TP + Q P Q +P QQP S P +QQS Q+ +Q
Sbjct: 486 SQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP-SQPPHQQSPAPYPSQQSTTQQH 544
Query: 409 TYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQH 468
S +Q S P PA S L++ + P PQ
Sbjct: 545 PQSQPPYSQPQAQSPYQQQQPQ----QPAPSTLSQ-QAAYPQ---------------PQS 584
Query: 469 QQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNL---- 524
QQ +A Q P P+ Q +FG Q + +T S +E NL
Sbjct: 585 QQSQQTAYSQQRFPP--------PQELSQD--SFGSQASSAPSMTSSKGGQEDMNLSLQS 634
Query: 525 -----PALNGH-----MRSHGGMR---ASPNLKQEEGEKVLP------PQPQPPLPPPPP 565
P L+G M + G + ++ + +GE+ P P P LP
Sbjct: 635 RPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG 694
Query: 566 PPPPPQLPPE--AESLTPMVMPVSVPVKLLPPKP---SSQGFTNSTVAAPSARDKPASSM 620
P P P P A+S + + P +VP +PP+P S + ++ S
Sbjct: 695 PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQ 754
Query: 621 SDDEMPVLEIPR------KHQPSVPKAEEPLKTVQEKKKFRHRPE------PLFIPPPPS 668
+ +MP P+ QPS + + + Q+ + P+ P P+
Sbjct: 755 RNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPN 814
Query: 669 YNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPY--TPPPMLSPVRQGS 721
YN P A+Y A + +P G + P +PPY PP +S G+
Sbjct: 815 YNALPNANYPSAGMAGG--INPMGAGGQMHGQP--GIPPYGTLPPGRMSHASMGN 865
Score = 67.8 bits (164), Expect = 6e-11
Identities = 124/443 (27%), Positives = 157/443 (35%), Gaps = 100/443 (22%)
Query: 177 PDSALRQLLSQKPMEPPAPAIPSRYQQVP----QQPH--PGFTGGLSKP-----ALQVGQ 225
P S + Q+ +P +P P QQ P QQ H PG G P +Q
Sbjct: 380 PSSPMDQMGKMRP-QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438
Query: 226 HPTQGHLYYDYQQPL--AQVPVQGGQPLQAP--QMLSQHMQQMQQ-HQYYPPQQQQQAGQ 280
G L Y Q P Q P GQ Q P S H QQ Q + PP Q A
Sbjct: 439 QSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA-- 496
Query: 281 QRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQ 340
Q Q+ Q+QP Q++ SQ PP QQP Q QQ P P Q +Q
Sbjct: 497 QPSYQQQPQSQPPQLQSSQ---PPYSQQPSQPPHQQSPA---------PYPSQQSTTQQH 544
Query: 341 QQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQ 400
Q QPP Y+ QA S Y Q+PQQP L QQ+ Q Q
Sbjct: 545 PQS---QPP--------YSQPQA----------QSPYQQQQPQQPAPSTLSQQAAYPQPQ 583
Query: 401 QREDSQLKTYSSDR-----------------QAQAMLSSHGDLGPPDTGMGDPASS--DL 441
++ SQ YS R A +M SS G + + SS DL
Sbjct: 584 SQQ-SQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDL 642
Query: 442 TRVSSTLPH------RPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGR----AQPGS 491
+ LP P +S SGI + + SP + HLP R + GS
Sbjct: 643 SGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGS 702
Query: 492 PESSGQ-------PKGAFGEQFDAKNKLTCSICLKEFKNLPALN--GHMRSHGGMRASPN 542
P S Q P G Q + S + P++N + G M+ +P
Sbjct: 703 PASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMH----PSMNQSSIAQDRGYMQRNPQ 758
Query: 543 LKQEEGEKVLPPQPQPPLPPPPP 565
+ Q PQP L P P
Sbjct: 759 MPQYSS-----PQPGSALSPRQP 776
Score = 46.6 bits (109), Expect = 1e-04
Identities = 87/392 (22%), Positives = 133/392 (33%), Gaps = 53/392 (13%)
Query: 272 PQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQP 331
P+ G + ++ PS+ P QQQQ Q+ Q S Q P P
Sbjct: 1296 PEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFP 1355
Query: 332 MMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQ-QPYSHPL 390
Q QQQQQ + +P P P + H G M Y Q QP
Sbjct: 1356 SQQTTMYQQQQQNYKRPMDGTYGP----PAKRHE------GEMYSVPYSTGQGQP----- 1400
Query: 391 YQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPH 450
QQ L Q + SQ + Q Q + + +G+ P ++
Sbjct: 1401 -QQQQLPPAQPQPASQQQAAQPSPQ-QDVYNQYGNAYP-------------ATATAATER 1445
Query: 451 RPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKN 510
RP P G + + +P Q ++P G P + G + +N
Sbjct: 1446 RPAGGPQNQFPFQFG-RDRVSAPPGTNAQQNMPP--QMMGGPIQASAEVAQQGTMWQGRN 1502
Query: 511 KLTCSICLKEFKNL----PALNGHMRSHGGMRASPNLKQE-----EGEKVLPPQPQPPLP 561
+T + ++ PA +G R+ + E G + P P P+P
Sbjct: 1503 DMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVP 1562
Query: 562 PPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPP-----KPSSQGFTNSTVAAPSARDK- 615
P PPP PP S+ + VS P L P PS F +S + A
Sbjct: 1563 PMTRPPPSNYQPP--PSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPV 1620
Query: 616 PASSMSDD--EMPVLEIPRKHQPSVPKAEEPL 645
PAS ++ + P++ P +A +P+
Sbjct: 1621 PASHIAPAPVQPPMIRRDITFPPGSVEATQPV 1652
Score = 41.2 bits (95), Expect = 0.006
Identities = 129/596 (21%), Positives = 189/596 (31%), Gaps = 130/596 (21%)
Query: 5 QLYKTNHVAHGSENLFYQQ--PPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHF-PQDT 61
Q+ K +G N + QQ PP G G H Y G PQ P++ Q
Sbjct: 386 QMGKMRPQPYGGTNPYSQQQGPPSGPQQG--HGYPGQPYGS--QTPQRYPMTMQGRAQSA 441
Query: 62 RDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGYQ 121
GL GQ GP + Q +G N P Q +P
Sbjct: 442 MGGLSYTQQIPPYGQQ------------GPSGYGQ-QGQTPYYNQQSPHPQQQQPP---- 484
Query: 122 YTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNM------AQVLHTQSAVMDG 175
YSQ +T H S+ Q +Q ++Q + +Q H QS
Sbjct: 485 --YSQQPPSQTP-------HAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP 535
Query: 176 APDSALRQL-LSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYY 234
+ S +Q SQ P P P + QQ PQQP P +Q Y
Sbjct: 536 SQQSTTQQHPQSQPPYSQPQAQSPYQQQQ-PQQPAPSTL--------------SQQAAYP 580
Query: 235 DYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQ 294
Q +Q Q PQ LSQ Q P + GQ+ +++ +Q++P
Sbjct: 581 QPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASS-APSMTSSKGGQEDMNL-SLQSRPSS 638
Query: 295 IRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMH--LQPPSYH 352
+ P L + +G++ P + Q +Q + P S H
Sbjct: 639 L-------PDLSGSIDDLPM-GTEGAL------SPGVSTSGISSSQGEQSNPAQSPFSPH 684
Query: 353 RDPH-----------QYTPEQAHTVQLIPLGSMSQYYYQEPQQPYS-------HPLYQQS 394
PH +P + PL + Q P +P S HP QS
Sbjct: 685 TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQS 744
Query: 395 HLSQHQ--QREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRP 452
++Q + + + Q+ YSS + A+ G TGMG +
Sbjct: 745 SIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNS------------ 792
Query: 453 LLSPSGIHLNNMGPQHQQLSPSAMWPQM----HLPDGRAQPGSPESSGQPKGAFGEQFDA 508
+ + GPQ Q P +P+ LP+ P GA G+
Sbjct: 793 --------MGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ 844
Query: 509 KNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPP 564
+ + LP S G PN+ +PPQ + PPP
Sbjct: 845 PG-------IPPYGTLPPGRMSHASMGNRPYGPNMAN------MPPQVGSGMCPPP 887
Score = 34.7 bits (78), Expect = 0.56
Identities = 88/377 (23%), Positives = 121/377 (32%), Gaps = 86/377 (22%)
Query: 175 GAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQ-HPTQGHLY 233
GAP L M P+ P + QQ QQ H + S G P+Q
Sbjct: 1303 GAPQPNLMPSNPDSGMYSPS-RYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTM 1361
Query: 234 YDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQ 293
Y QQ + P+ G Y PP ++ + + Q QPQ
Sbjct: 1362 YQQQQQNYKRPMDG--------------------TYGPPAKRHEGEMYSVPYSTGQGQPQ 1401
Query: 294 QIRPSQPQPPPQQQQ------PQQLQLQQRQGSM------------------QIPQYYQP 329
Q + QP P QQ PQQ Q + Q P +
Sbjct: 1402 QQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGR 1461
Query: 330 QPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHP 389
+ QQ M PP P Q + E A + + Y Y Q S P
Sbjct: 1462 DRVSAPPGTNAQQNM---PPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAP 1518
Query: 390 LYQQSHLSQHQQREDSQLKTYSSDRQA--QAMLSSHGD--------------LGPPDTGM 433
Q R D L T D++A + SHG PP +
Sbjct: 1519 ---QGPAYHGVNRTDEMLHT---DQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNY 1572
Query: 434 GDPAS--SDLTRVSSTLP-HRPL---LSP-------SGIHLNNMGP--QHQQLSPSAMWP 478
P S + + +VSS P RP+ SP SG+ + GP ++P+ + P
Sbjct: 1573 QPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQP 1632
Query: 479 QMHLPDGRAQPGSPESS 495
M D PGS E++
Sbjct: 1633 PMIRRDITFPPGSVEAT 1649
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 69.3 bits (168), Expect = 2e-11
Identities = 133/535 (24%), Positives = 189/535 (35%), Gaps = 99/535 (18%)
Query: 247 GGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIR--PSQP---Q 301
GGQPL S M QM + + P QQ Q + PQQ P QP Q
Sbjct: 370 GGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQ----QGPPSGPQQGHGYPGQPYGSQ 425
Query: 302 PPPQQQQPQQLQLQQRQGSM----QIPQYYQPQPMMQHLQEQ----QQQQMH--LQPPSY 351
P + Q + Q G + QIP Y Q P Q Q QQ H Q P Y
Sbjct: 426 TPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPY 485
Query: 352 HRDPHQYTPEQAHTVQLIPLGSMSQYYYQEP---QQPYSHPLYQQSHLSQHQQREDSQLK 408
+ P TP + Q P Q +P QQP S P +QQS Q+ +Q
Sbjct: 486 SQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQP-SQPPHQQSPAPYPSQQSTTQQH 544
Query: 409 TYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQH 468
S +Q S P PA S L++ + P PQ
Sbjct: 545 PQSQPPYSQPQAQSPYQQQQPQ----QPAPSTLSQ-QAAYPQ---------------PQS 584
Query: 469 QQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNL---- 524
QQ +A Q P P+ Q +FG Q + +T S +E NL
Sbjct: 585 QQSQQTAYSQQRFPP--------PQELSQD--SFGSQASSAPSMTSSKGGQEDMNLSLQS 634
Query: 525 -----PALNGH-----MRSHGGMR---ASPNLKQEEGEKVLP------PQPQPPLPPPPP 565
P L+G M + G + ++ + +GE+ P P P LP
Sbjct: 635 RPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG 694
Query: 566 PPPPPQLPPE--AESLTPMVMPVSVPVKLLPPKP---SSQGFTNSTVAAPSARDKPASSM 620
P P P P A+S + + P +VP +PP+P S + ++ S
Sbjct: 695 PSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQ 754
Query: 621 SDDEMPVLEIPR------KHQPSVPKAEEPLKTVQEKKKFRHRPE------PLFIPPPPS 668
+ +MP P+ QPS + + + Q+ + P+ P P+
Sbjct: 755 RNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPN 814
Query: 669 YNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPY--TPPPMLSPVRQGS 721
YN P A+Y A + +P G + P +PPY PP +S G+
Sbjct: 815 YNALPNANYPSAGMAGG--INPMGAGGQMHGQP--GIPPYGTLPPGRMSHASMGN 865
Score = 67.8 bits (164), Expect = 6e-11
Identities = 124/443 (27%), Positives = 157/443 (35%), Gaps = 100/443 (22%)
Query: 177 PDSALRQLLSQKPMEPPAPAIPSRYQQVP----QQPH--PGFTGGLSKP-----ALQVGQ 225
P S + Q+ +P +P P QQ P QQ H PG G P +Q
Sbjct: 380 PSSPMDQMGKMRP-QPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA 438
Query: 226 HPTQGHLYYDYQQPL--AQVPVQGGQPLQAP--QMLSQHMQQMQQ-HQYYPPQQQQQAGQ 280
G L Y Q P Q P GQ Q P S H QQ Q + PP Q A
Sbjct: 439 QSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHA-- 496
Query: 281 QRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQ 340
Q Q+ Q+QP Q++ SQ PP QQP Q QQ P P Q +Q
Sbjct: 497 QPSYQQQPQSQPPQLQSSQ---PPYSQQPSQPPHQQSPA---------PYPSQQSTTQQH 544
Query: 341 QQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQ 400
Q QPP Y+ QA S Y Q+PQQP L QQ+ Q Q
Sbjct: 545 PQS---QPP--------YSQPQA----------QSPYQQQQPQQPAPSTLSQQAAYPQPQ 583
Query: 401 QREDSQLKTYSSDR-----------------QAQAMLSSHGDLGPPDTGMGDPASS--DL 441
++ SQ YS R A +M SS G + + SS DL
Sbjct: 584 SQQ-SQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDL 642
Query: 442 TRVSSTLPH------RPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGR----AQPGS 491
+ LP P +S SGI + + SP + HLP R + GS
Sbjct: 643 SGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGS 702
Query: 492 PESSGQ-------PKGAFGEQFDAKNKLTCSICLKEFKNLPALN--GHMRSHGGMRASPN 542
P S Q P G Q + S + P++N + G M+ +P
Sbjct: 703 PASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMH----PSMNQSSIAQDRGYMQRNPQ 758
Query: 543 LKQEEGEKVLPPQPQPPLPPPPP 565
+ Q PQP L P P
Sbjct: 759 MPQYSS-----PQPGSALSPRQP 776
Score = 41.2 bits (95), Expect = 0.006
Identities = 129/596 (21%), Positives = 189/596 (31%), Gaps = 130/596 (21%)
Query: 5 QLYKTNHVAHGSENLFYQQ--PPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHF-PQDT 61
Q+ K +G N + QQ PP G G H Y G PQ P++ Q
Sbjct: 386 QMGKMRPQPYGGTNPYSQQQGPPSGPQQG--HGYPGQPYGS--QTPQRYPMTMQGRAQSA 441
Query: 62 RDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGYQ 121
GL GQ GP + Q +G N P Q +P
Sbjct: 442 MGGLSYTQQIPPYGQQ------------GPSGYGQ-QGQTPYYNQQSPHPQQQQPP---- 484
Query: 122 YTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNM------AQVLHTQSAVMDG 175
YSQ +T H S+ Q +Q ++Q + +Q H QS
Sbjct: 485 --YSQQPPSQTP-------HAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYP 535
Query: 176 APDSALRQL-LSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYY 234
+ S +Q SQ P P P + QQ PQQP P +Q Y
Sbjct: 536 SQQSTTQQHPQSQPPYSQPQAQSPYQQQQ-PQQPAPSTL--------------SQQAAYP 580
Query: 235 DYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQ 294
Q +Q Q PQ LSQ Q P + GQ+ +++ +Q++P
Sbjct: 581 QPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASS-APSMTSSKGGQEDMNL-SLQSRPSS 638
Query: 295 IRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMH--LQPPSYH 352
+ P L + +G++ P + Q +Q + P S H
Sbjct: 639 L-------PDLSGSIDDLPM-GTEGAL------SPGVSTSGISSSQGEQSNPAQSPFSPH 684
Query: 353 RDPH-----------QYTPEQAHTVQLIPLGSMSQYYYQEPQQPYS-------HPLYQQS 394
PH +P + PL + Q P +P S HP QS
Sbjct: 685 TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQS 744
Query: 395 HLSQHQ--QREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRP 452
++Q + + + Q+ YSS + A+ G TGMG +
Sbjct: 745 SIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNS------------ 792
Query: 453 LLSPSGIHLNNMGPQHQQLSPSAMWPQM----HLPDGRAQPGSPESSGQPKGAFGEQFDA 508
+ + GPQ Q P +P+ LP+ P GA G+
Sbjct: 793 --------MGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ 844
Query: 509 KNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPP 564
+ + LP S G PN+ +PPQ + PPP
Sbjct: 845 PG-------IPPYGTLPPGRMSHASMGNRPYGPNMAN------MPPQVGSGMCPPP 887
Score = 32.7 bits (73), Expect = 2.1
Identities = 43/165 (26%), Positives = 52/165 (31%), Gaps = 7/165 (4%)
Query: 215 GLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQ---MLSQHMQQMQQHQYYP 271
GL A+ QH G Y D + + +G APQ M S M YP
Sbjct: 1267 GLGNVAMGPRQHYPYGGPY-DRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYP 1325
Query: 272 PQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQP 331
PQQQQ QQR Q Q P P Q QQ Q + P + P
Sbjct: 1326 PQQQQ-QQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSP 1384
Query: 332 MMQHLQEQQQQQMHLQP--PSYHRDPHQYTPEQAHTVQLIPLGSM 374
+ P P+ H P P P GS+
Sbjct: 1385 SKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSV 1429
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 67.0 bits (162), Expect = 1e-10
Identities = 59/170 (34%), Positives = 79/170 (46%), Gaps = 12/170 (7%)
Query: 235 DYQQPLAQVPVQGGQPLQAPQMLS-QHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQ 293
D Q+PL QVPV + PQ+++ Q MQQ+ Q Q PQQ Q QQ+ ++ Q Q Q
Sbjct: 80 DKQRPL-QVPVSVA--MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQ 136
Query: 294 QI-RPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYH 352
+ + Q Q Q Q QQ Q QQ+Q Q Q Q Q Q Q+QQQQQ Q P
Sbjct: 137 EFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQ 196
Query: 353 RDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQR 402
Q +Q + + Q +Q+ Q L QQ HL Q++
Sbjct: 197 AKEQQQQQQQQQQL------AAQQLVFQQ-QLLQMQQLQQQQHLLSLQRQ 239
Score = 63.5 bits (153), Expect = 1e-09
Identities = 59/201 (29%), Positives = 83/201 (41%), Gaps = 17/201 (8%)
Query: 215 GLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQ 274
G+S + Q+ G D ++ V + Q QA Q Q + Q Q P+
Sbjct: 19 GMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKS 78
Query: 275 QQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQ--QPQQLQ--LQQRQGSM----QIPQY 326
+ ++ + PQ I P Q Q QQQ PQQLQ LQQ+Q M Q+ ++
Sbjct: 79 SDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEF 138
Query: 327 YQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPY 386
Y+ Q HLQ QQQQ Q + Q +Q Q Q Q+ QQ
Sbjct: 139 YKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQ--------QQQQQQQQQQQ 190
Query: 387 SHPLYQQSHLSQHQQREDSQL 407
HP +Q+ Q QQ++ QL
Sbjct: 191 QHP-GKQAKEQQQQQQQQQQL 210
Score = 63.5 bits (153), Expect = 1e-09
Identities = 66/198 (33%), Positives = 82/198 (41%), Gaps = 26/198 (13%)
Query: 176 APDSALRQLLSQKP----MEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGH 231
+P S+ +Q Q P M P P + QQ+ QQ LS LQ Q
Sbjct: 75 SPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQV------LSPQQLQALLQQQQAV 128
Query: 232 LYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQ 291
+ L Q +Q Q Q+ Q +QQ QQ Q QQQQQ QQ+ Q+ Q Q
Sbjct: 129 M-------LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 181
Query: 292 PQQIRPSQPQPP--------PQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQ 343
QQ + Q Q P QQQQ QQL QQ Q+ Q Q Q QHL Q+Q
Sbjct: 182 QQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQ-QQQHLLSLQRQG 240
Query: 344 MHLQPPSYHRDPHQYTPE 361
+ PP P Q P+
Sbjct: 241 LISIPPGQAALPVQSLPQ 258
Score = 60.5 bits (145), Expect = 1e-08
Identities = 73/266 (27%), Positives = 100/266 (37%), Gaps = 40/266 (15%)
Query: 213 TGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQ----APQMLSQHMQQMQQ-- 266
T GL P Q P Q + P P Q Q LQ +PQ L +QQ Q
Sbjct: 70 TSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVM 129
Query: 267 ------HQYYPPQQQQ-------QAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQ 313
++Y QQ+Q Q QQ+ Q+ Q Q QQ + Q Q QQQQ QQ Q
Sbjct: 130 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-Q 188
Query: 314 LQQRQGSMQIPQYYQPQPMMQHLQEQQQ--QQMHLQPPSYHRDPHQYTPEQAHTVQLIPL 371
QQ G Q + Q Q Q L QQ QQ LQ + H + ++ + IP
Sbjct: 189 QQQHPGK-QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLIS-IPP 246
Query: 372 GSMSQYYYQEPQQPYSHPLYQQ--SHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPP 429
G + PQ S QQ ++ ED+ +K HG L
Sbjct: 247 GQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIK--------------HGGLDLT 292
Query: 430 DTGMGDPASSDLTRVSSTLPHRPLLS 455
SS+ ++ S + H +++
Sbjct: 293 TNNSSSTTSSNTSKASPPITHHSIVN 318
Score = 53.1 bits (126), Expect = 2e-06
Identities = 52/169 (30%), Positives = 64/169 (37%), Gaps = 10/169 (5%)
Query: 181 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDY-QQP 239
++Q+L Q+ + P + QQ L + LQ Q L+ QQ
Sbjct: 104 MQQILQQQVLSPQQLQALLQQQQAVM---------LQQQQLQEFYKKQQEQLHLQLLQQQ 154
Query: 240 LAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQ 299
Q Q Q Q Q Q QQ QQ Q QQQQ G+Q Q+ Q Q QQ+ Q
Sbjct: 155 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214
Query: 300 PQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQP 348
Q Q QQLQ QQ S+Q P L Q Q L P
Sbjct: 215 LVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 263
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 66.6 bits (161), Expect = 1e-10
Identities = 68/244 (27%), Positives = 93/244 (38%), Gaps = 42/244 (17%)
Query: 553 PPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSA 612
PP P PP PPPPPPPPPP LPP S P ++P P ++ F T +A
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPT-SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTA 2466
Query: 613 RDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPL--------FIP 664
+ + +PV I P VP ++ F HRPEP IP
Sbjct: 2467 ------VLRSNGLPVTRICTTAPPPVPPKP---SSIPSGLVFTHRPEPSKPPIAPKPVIP 2517
Query: 665 PPPSYNPNPAASY---SGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGS 721
P+ P + +G +L S + D+ L PT L P++ + S
Sbjct: 2518 QLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHS--------NKSS 2569
Query: 722 GLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTP--GPGEQTVDVEP 779
FS L + LP P TPT +S +T P P + V VEP
Sbjct: 2570 PRFSKSLTETY---VVITLPSEPGTPT--------DSSASQAITSWPLGSPSKDLVSVEP 2618
Query: 780 RINI 783
++
Sbjct: 2619 VFSV 2622
Score = 54.7 bits (130), Expect = 5e-07
Identities = 82/345 (23%), Positives = 117/345 (33%), Gaps = 58/345 (16%)
Query: 393 QSHLSQHQQREDSQLKTYSSDRQAQAMLSSH-GDLGPPDTGMGDPASSDLTRVSSTLPHR 451
+S ++ + S + + S+ A + +SS P D AS + T + +
Sbjct: 139 KSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQK 198
Query: 452 PLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLP--DGRAQPGSPES---------SGQPKG 500
P GI + P QQ P + P+ P D Q G+P+S QP G
Sbjct: 199 EQGKPEGI----IKPPLQQQPPKPI-PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG 253
Query: 501 AFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEE---GEKVLPPQPQ 557
G+ + + + LP R P KQ + GE V P P
Sbjct: 254 T-GKPIQGPTQTPQT----DHAKLPLQRDASR--------PQTKQADIVRGESVKPSLPS 300
Query: 558 PPLPP---PPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARD 614
P PP P P PP Q P +S P + P L P G V P
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360
Query: 615 KPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPA 674
PA QP P A+ P + +K +P P + PP PA
Sbjct: 361 PPA-----------------QPLGP-AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA 402
Query: 675 ASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQ 719
A Q+ +P+ L P + P P P +PV+Q
Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQ----QPGLQSPAKAPGPTKTPVQQ 443
Score = 48.5 bits (114), Expect = 4e-05
Identities = 103/450 (22%), Positives = 151/450 (33%), Gaps = 68/450 (15%)
Query: 277 QAGQQRISMQEIQTQPQQIRPSQP-QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQH 335
+A Q+ + ++ Q +Q +P +PP QQQ P+ + QQ G + Q P +
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTP----KS 238
Query: 336 LQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSH 395
+ QQ +++ QPP + P Q T Q P Q H
Sbjct: 239 ISSQQPEKIKSQPPGTGK------PIQGPT--------------QTP---------QTDH 269
Query: 396 LSQHQQREDSQLKTYSSD--RQAQAMLSSHGDLGPP---DTGMGDPASSDLTRVSSTLPH 450
QR+ S+ +T +D R S PP T PA S P
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 451 RPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKN 510
+P PSG+ P QQ P + P + P P P +P +Q ++
Sbjct: 330 KPPAQPSGL----TKPLAQQ--PGTVKPPVQPPGTTKPPAQPLGPAKPP---AQQTGSEK 380
Query: 511 KLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQP--QPPLPPPPPPPP 568
+ K P + G A P +Q K L QP Q P P P
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPG-PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT 439
Query: 569 PPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVL 628
P Q P P +P + P +S T T PS PA P
Sbjct: 440 PVQQPG----------PGKIPAQQAGPGKTSAQQTGPT-KPPSQLPGPAKPPPQQPGPAK 488
Query: 629 EIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLR 688
P++ + P +++P T K +P P P + P + G+ +Q
Sbjct: 489 PPPQQPGSAKPPSQQPGST----KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544
Query: 689 SPRVLGDHLLLDPTHELPPYTP--PPMLSP 716
SP P + P PP +SP
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574
Score = 46.6 bits (109), Expect = 1e-04
Identities = 115/518 (22%), Positives = 173/518 (33%), Gaps = 114/518 (22%)
Query: 186 SQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPV 245
S+ P++ P P P Q ++ P G +KP Q +PLAQ P
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQP----GPAKPPAQPS----------GLTKPLAQQPG 347
Query: 246 QGGQPLQAPQMLSQHMQQMQQHQYYPPQQQ--------QQAGQQRISMQE--IQTQPQQI 295
P+Q P Q + + PP QQ +Q G + ++ +T QQ
Sbjct: 348 TVKPPVQPPGTTKPPAQPLGPAK--PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405
Query: 296 RPSQP------QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQE------QQQQQ 343
P++P P P QQP + G + P QP P Q+ QQ
Sbjct: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP-VQQPGPGKIPAQQAGPGKTSAQQT 464
Query: 344 MHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYS-HPLYQQSHLSQHQQR 402
+PPS P + P+Q + PQQP S P QQ ++ +
Sbjct: 465 GPTKPPSQLPGPAKPPPQQPGPAK------------PPPQQPGSAKPPSQQPGSTKPPPQ 512
Query: 403 EDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTR----VSSTLPHRPLLSPSG 458
+ K + S P PA + VS T +PL P+
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPT- 571
Query: 459 IHLNNMGPQHQQLSPSAMWP-------QMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNK 511
+ + P Q L P + P +H+P+ K F + +
Sbjct: 572 VSPSAKQPPSQGL-PKTICPLCNTTELLLHVPE--------------KANFNTCTECQTT 616
Query: 512 LTCSIC-------LKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPP 564
+ CS+C L E K LN M+ G +P +P PQP L P
Sbjct: 617 V-CSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP----------VPSSPQPKLKTAP 665
Query: 565 ---------PPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDK 615
P P Q P+ ++ P P PP Q + + +A + +
Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDA-APKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 616 PASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKK 653
A S+S P +PSVP ++ +K K
Sbjct: 725 EADSLSKPAPP-------KEPSVPSEQDKAPVADDKPK 755
Score = 45.4 bits (106), Expect = 3e-04
Identities = 128/609 (21%), Positives = 205/609 (33%), Gaps = 90/609 (14%)
Query: 175 GAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYY 234
G P +Q Q P + P P + QQP PG PA Q G T
Sbjct: 416 GTPKPLAQQPGLQSPAKAPGPT-----KTPVQQPGPG-----KIPAQQAGPGKTSAQQTG 465
Query: 235 DYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQ--------QQAGQQRISMQ 286
+ P +Q+P P Q P QQ + PP QQ QQ G + S Q
Sbjct: 466 PTKPP-SQLPGPAKPPPQQPGPAKPPPQQPGSAK--PPSQQPGSTKPPPQQPGPAKPSPQ 522
Query: 287 EI-QTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMH 345
+ T+P +P +P QQ P + Q Q + + Q +P
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ--QSTKPVSQTGSGKP-------------- 566
Query: 346 LQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQ-----QSHLSQHQ 400
LQPP+ Q P Q + PL + ++ P++ + + S +
Sbjct: 567 LQPPTVSPSAKQ-PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP 625
Query: 401 QREDSQLKTYSSDRQAQAMLSSHGDLGP----PDTGMGDPASSDLTRVSSTLPHRPLLSP 456
+++K + Q + GDL P P + + + VS + P SP
Sbjct: 626 NPHLTEVKEWLC-LNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP 684
Query: 457 SGIHLN----NMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKL 512
+ P+ ++ P P +H PE+ K A ++ ++
Sbjct: 685 KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744
Query: 513 TCSICLKEFKNLPAL---NGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPP 569
+ + P + + S P++ + + + PPL P
Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL-KTDSAKPS 803
Query: 570 PQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLE 629
PP E ++P P+P+S + ++ P SS S + V
Sbjct: 804 QSFPPTGEKVSPFDSKAI-------PRPASD---SKIISHPG-----PSSESKGQKQVDP 848
Query: 630 IPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRS 689
+ +K +P KA+ + + K P P P PP P P A + T QS
Sbjct: 849 VQKKEEPK--KAQTKMSPKPDAK-----PMPKGSPTPP--GPRPTAGQTVPTPQQSPKPQ 899
Query: 690 PRVLGDHLLLDPTHELP---PYTPPPMLSPVRQGSGL-----FSNVLISGHGPGAHPQL- 740
+ L L + P P TP ++ G G SN++ + PG H Q
Sbjct: 900 EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG 959
Query: 741 PLTPLTPTP 749
P P+ P
Sbjct: 960 PGAPMKQAP 968
Score = 36.6 bits (83), Expect = 0.15
Identities = 32/107 (29%), Positives = 43/107 (40%), Gaps = 17/107 (15%)
Query: 227 PTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHM---QQMQQHQYYPPQQQQQAGQQRI 283
PT + Y Y P P QAP +Q QQ HQ P Q Q Q
Sbjct: 3881 PTSPYTQYQYSSPAL--------PTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVA 3932
Query: 284 SMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQ 330
+M + Q++P+ P P P Q P Q+ + Q Q Q Y +P+
Sbjct: 3933 TM----SFTPQVQPT-PTPQPSYQLPSQMMVIQ-QKPRQTTLYLEPK 3973
Score = 34.3 bits (77), Expect = 0.73
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 3/86 (3%)
Query: 266 QHQYYPPQQQQQAGQQRISMQEIQTQP---QQIRPSQPQPPPQQQQPQQLQLQQRQGSMQ 322
Q+QY P QA + Q QQ+ P Q QP Q Q +
Sbjct: 3887 QYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTP 3946
Query: 323 IPQYYQPQPMMQHLQEQQQQQMHLQP 348
P Y P MM Q+ +Q ++L+P
Sbjct: 3947 QPSYQLPSQMMVIQQKPRQTTLYLEP 3972
Score = 32.7 bits (73), Expect = 2.1
Identities = 43/190 (22%), Positives = 76/190 (40%), Gaps = 22/190 (11%)
Query: 956 EEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEG---PPLQALGQPSGS 1012
++ + ++++EE + + S K + +PK PP P PT G P Q +P
Sbjct: 844 KQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP--RPTAGQTVPTPQQSPKPQEQ 901
Query: 1013 FICEMPNCGAVFSS--RQALNGHARIHG-----GTNQVTKARGAIPSGKQKPGGTQSGYC 1065
N G++ + Q + G G + ++A I + Q +QSG
Sbjct: 902 SRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG-- 959
Query: 1066 SVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFA 1125
+P + PT+ P K G ++ A K+ ++E + A+K
Sbjct: 960 --PGAPMKQAPAPSQPPTSQGPPKSTG------QAPPAPAKSIPVKKETKAPAAEKLEPK 1011
Query: 1126 AEMAATIERT 1135
AE A T++RT
Sbjct: 1012 AEQAPTVKRT 1021
Score = 32.3 bits (72), Expect = 2.8
Identities = 45/197 (22%), Positives = 69/197 (35%), Gaps = 26/197 (13%)
Query: 542 NLKQEEGEKVLPPQPQPPLP----PPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKP 597
NL G+ Q P P P P PP Q PP++ P S+PVK P
Sbjct: 944 NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
Query: 598 SSQGFTNSTVAAPSAR----DKPASSMSDDEMPVLE-----IPRKHQPSVPKAEEPLKTV 648
+++ AP+ + +K + D + E +P K + S PK E
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS-PKPESTCPLC 1062
Query: 649 QEKKKFRHRPEPLF---------IPPPPSYNPNPAASYSGATL---YQSQLRSPRVLGDH 696
+ + + P F + +NP P + L Q+Q LGD
Sbjct: 1063 KTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDI 1122
Query: 697 LLLDPTHELPPYTPPPM 713
+ P P +P P+
Sbjct: 1123 RKMPPAPSGPKASPMPV 1139
Score = 32.3 bits (72), Expect = 2.8
Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 274 QQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMM 333
++Q+ + ++E+Q+ Q + Q ++++ Q ++Q + Q Q Q Q +
Sbjct: 3246 REQEKIMVQKKLEELQSMKQHLLFQQ-----EEERQAQFMMRQETLAQQQLQLEQIQQLQ 3300
Query: 334 QHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLI 369
Q L +Q ++Q Q Y+ DP Q T Q I
Sbjct: 3301 QQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAI 3336
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 66.6 bits (161), Expect = 1e-10
Identities = 68/244 (27%), Positives = 93/244 (38%), Gaps = 42/244 (17%)
Query: 553 PPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSA 612
PP P PP PPPPPPPPPP LPP S P ++P P ++ F T +A
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPT-SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTA 2466
Query: 613 RDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPL--------FIP 664
+ + +PV I P VP ++ F HRPEP IP
Sbjct: 2467 ------VLRSNGLPVTRICTTAPPPVPPKP---SSIPSGLVFTHRPEPSKPPIAPKPVIP 2517
Query: 665 PPPSYNPNPAASY---SGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGS 721
P+ P + +G +L S + D+ L PT L P++ + S
Sbjct: 2518 QLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHS--------NKSS 2569
Query: 722 GLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTP--GPGEQTVDVEP 779
FS L + LP P TPT +S +T P P + V VEP
Sbjct: 2570 PRFSKSLTETY---VVITLPSEPGTPT--------DSSASQAITSWPLGSPSKDLVSVEP 2618
Query: 780 RINI 783
++
Sbjct: 2619 VFSV 2622
Score = 54.7 bits (130), Expect = 5e-07
Identities = 82/345 (23%), Positives = 117/345 (33%), Gaps = 58/345 (16%)
Query: 393 QSHLSQHQQREDSQLKTYSSDRQAQAMLSSH-GDLGPPDTGMGDPASSDLTRVSSTLPHR 451
+S ++ + S + + S+ A + +SS P D AS + T + +
Sbjct: 139 KSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQK 198
Query: 452 PLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLP--DGRAQPGSPES---------SGQPKG 500
P GI + P QQ P + P+ P D Q G+P+S QP G
Sbjct: 199 EQGKPEGI----IKPPLQQQPPKPI-PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG 253
Query: 501 AFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEE---GEKVLPPQPQ 557
G+ + + + LP R P KQ + GE V P P
Sbjct: 254 T-GKPIQGPTQTPQT----DHAKLPLQRDASR--------PQTKQADIVRGESVKPSLPS 300
Query: 558 PPLPP---PPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARD 614
P PP P P PP Q P +S P + P L P G V P
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360
Query: 615 KPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPA 674
PA QP P A+ P + +K +P P + PP PA
Sbjct: 361 PPA-----------------QPLGP-AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA 402
Query: 675 ASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQ 719
A Q+ +P+ L P + P P P +PV+Q
Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQ----QPGLQSPAKAPGPTKTPVQQ 443
Score = 48.5 bits (114), Expect = 4e-05
Identities = 103/450 (22%), Positives = 151/450 (33%), Gaps = 68/450 (15%)
Query: 277 QAGQQRISMQEIQTQPQQIRPSQP-QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQH 335
+A Q+ + ++ Q +Q +P +PP QQQ P+ + QQ G + Q P +
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTP----KS 238
Query: 336 LQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSH 395
+ QQ +++ QPP + P Q T Q P Q H
Sbjct: 239 ISSQQPEKIKSQPPGTGK------PIQGPT--------------QTP---------QTDH 269
Query: 396 LSQHQQREDSQLKTYSSD--RQAQAMLSSHGDLGPP---DTGMGDPASSDLTRVSSTLPH 450
QR+ S+ +T +D R S PP T PA S P
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 451 RPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKN 510
+P PSG+ P QQ P + P + P P P +P +Q ++
Sbjct: 330 KPPAQPSGL----TKPLAQQ--PGTVKPPVQPPGTTKPPAQPLGPAKPP---AQQTGSEK 380
Query: 511 KLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQP--QPPLPPPPPPPP 568
+ K P + G A P +Q K L QP Q P P P
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPG-PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT 439
Query: 569 PPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVL 628
P Q P P +P + P +S T T PS PA P
Sbjct: 440 PVQQPG----------PGKIPAQQAGPGKTSAQQTGPT-KPPSQLPGPAKPPPQQPGPAK 488
Query: 629 EIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLR 688
P++ + P +++P T K +P P P + P + G+ +Q
Sbjct: 489 PPPQQPGSAKPPSQQPGST----KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544
Query: 689 SPRVLGDHLLLDPTHELPPYTP--PPMLSP 716
SP P + P PP +SP
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574
Score = 46.6 bits (109), Expect = 1e-04
Identities = 115/518 (22%), Positives = 173/518 (33%), Gaps = 114/518 (22%)
Query: 186 SQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPV 245
S+ P++ P P P Q ++ P G +KP Q +PLAQ P
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQP----GPAKPPAQPS----------GLTKPLAQQPG 347
Query: 246 QGGQPLQAPQMLSQHMQQMQQHQYYPPQQQ--------QQAGQQRISMQE--IQTQPQQI 295
P+Q P Q + + PP QQ +Q G + ++ +T QQ
Sbjct: 348 TVKPPVQPPGTTKPPAQPLGPAK--PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405
Query: 296 RPSQP------QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQE------QQQQQ 343
P++P P P QQP + G + P QP P Q+ QQ
Sbjct: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP-VQQPGPGKIPAQQAGPGKTSAQQT 464
Query: 344 MHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYS-HPLYQQSHLSQHQQR 402
+PPS P + P+Q + PQQP S P QQ ++ +
Sbjct: 465 GPTKPPSQLPGPAKPPPQQPGPAK------------PPPQQPGSAKPPSQQPGSTKPPPQ 512
Query: 403 EDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTR----VSSTLPHRPLLSPSG 458
+ K + S P PA + VS T +PL P+
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPT- 571
Query: 459 IHLNNMGPQHQQLSPSAMWP-------QMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNK 511
+ + P Q L P + P +H+P+ K F + +
Sbjct: 572 VSPSAKQPPSQGL-PKTICPLCNTTELLLHVPE--------------KANFNTCTECQTT 616
Query: 512 LTCSIC-------LKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPP 564
+ CS+C L E K LN M+ G +P +P PQP L P
Sbjct: 617 V-CSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP----------VPSSPQPKLKTAP 665
Query: 565 ---------PPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDK 615
P P Q P+ ++ P P PP Q + + +A + +
Sbjct: 666 VTTTSAVSKSSPQPQQTSPKKDA-APKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 616 PASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKK 653
A S+S P +PSVP ++ +K K
Sbjct: 725 EADSLSKPAPP-------KEPSVPSEQDKAPVADDKPK 755
Score = 45.4 bits (106), Expect = 3e-04
Identities = 128/609 (21%), Positives = 205/609 (33%), Gaps = 90/609 (14%)
Query: 175 GAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYY 234
G P +Q Q P + P P + QQP PG PA Q G T
Sbjct: 416 GTPKPLAQQPGLQSPAKAPGPT-----KTPVQQPGPG-----KIPAQQAGPGKTSAQQTG 465
Query: 235 DYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQ--------QQAGQQRISMQ 286
+ P +Q+P P Q P QQ + PP QQ QQ G + S Q
Sbjct: 466 PTKPP-SQLPGPAKPPPQQPGPAKPPPQQPGSAK--PPSQQPGSTKPPPQQPGPAKPSPQ 522
Query: 287 EI-QTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMH 345
+ T+P +P +P QQ P + Q Q + + Q +P
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ--QSTKPVSQTGSGKP-------------- 566
Query: 346 LQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQ-----QSHLSQHQ 400
LQPP+ Q P Q + PL + ++ P++ + + S +
Sbjct: 567 LQPPTVSPSAKQ-PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP 625
Query: 401 QREDSQLKTYSSDRQAQAMLSSHGDLGP----PDTGMGDPASSDLTRVSSTLPHRPLLSP 456
+++K + Q + GDL P P + + + VS + P SP
Sbjct: 626 NPHLTEVKEWLC-LNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP 684
Query: 457 SGIHLN----NMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKL 512
+ P+ ++ P P +H PE+ K A ++ ++
Sbjct: 685 KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744
Query: 513 TCSICLKEFKNLPAL---NGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPP 569
+ + P + + S P++ + + + PPL P
Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL-KTDSAKPS 803
Query: 570 PQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLE 629
PP E ++P P+P+S + ++ P SS S + V
Sbjct: 804 QSFPPTGEKVSPFDSKAI-------PRPASD---SKIISHPG-----PSSESKGQKQVDP 848
Query: 630 IPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRS 689
+ +K +P KA+ + + K P P P PP P P A + T QS
Sbjct: 849 VQKKEEPK--KAQTKMSPKPDAK-----PMPKGSPTPP--GPRPTAGQTVPTPQQSPKPQ 899
Query: 690 PRVLGDHLLLDPTHELP---PYTPPPMLSPVRQGSGL-----FSNVLISGHGPGAHPQL- 740
+ L L + P P TP ++ G G SN++ + PG H Q
Sbjct: 900 EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG 959
Query: 741 PLTPLTPTP 749
P P+ P
Sbjct: 960 PGAPMKQAP 968
Score = 36.6 bits (83), Expect = 0.15
Identities = 32/107 (29%), Positives = 43/107 (40%), Gaps = 17/107 (15%)
Query: 227 PTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHM---QQMQQHQYYPPQQQQQAGQQRI 283
PT + Y Y P P QAP +Q QQ HQ P Q Q Q
Sbjct: 3881 PTSPYTQYQYSSPAL--------PTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVA 3932
Query: 284 SMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQ 330
+M + Q++P+ P P P Q P Q+ + Q Q Q Y +P+
Sbjct: 3933 TM----SFTPQVQPT-PTPQPSYQLPSQMMVIQ-QKPRQTTLYLEPK 3973
Score = 34.3 bits (77), Expect = 0.73
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 3/86 (3%)
Query: 266 QHQYYPPQQQQQAGQQRISMQEIQTQP---QQIRPSQPQPPPQQQQPQQLQLQQRQGSMQ 322
Q+QY P QA + Q QQ+ P Q QP Q Q +
Sbjct: 3887 QYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTP 3946
Query: 323 IPQYYQPQPMMQHLQEQQQQQMHLQP 348
P Y P MM Q+ +Q ++L+P
Sbjct: 3947 QPSYQLPSQMMVIQQKPRQTTLYLEP 3972
Score = 32.7 bits (73), Expect = 2.1
Identities = 43/190 (22%), Positives = 76/190 (40%), Gaps = 22/190 (11%)
Query: 956 EEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEG---PPLQALGQPSGS 1012
++ + ++++EE + + S K + +PK PP P PT G P Q +P
Sbjct: 844 KQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP--RPTAGQTVPTPQQSPKPQEQ 901
Query: 1013 FICEMPNCGAVFSS--RQALNGHARIHG-----GTNQVTKARGAIPSGKQKPGGTQSGYC 1065
N G++ + Q + G G + ++A I + Q +QSG
Sbjct: 902 SRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG-- 959
Query: 1066 SVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFA 1125
+P + PT+ P K G ++ A K+ ++E + A+K
Sbjct: 960 --PGAPMKQAPAPSQPPTSQGPPKSTG------QAPPAPAKSIPVKKETKAPAAEKLEPK 1011
Query: 1126 AEMAATIERT 1135
AE A T++RT
Sbjct: 1012 AEQAPTVKRT 1021
Score = 32.3 bits (72), Expect = 2.8
Identities = 45/197 (22%), Positives = 69/197 (35%), Gaps = 26/197 (13%)
Query: 542 NLKQEEGEKVLPPQPQPPLP----PPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKP 597
NL G+ Q P P P P PP Q PP++ P S+PVK P
Sbjct: 944 NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
Query: 598 SSQGFTNSTVAAPSAR----DKPASSMSDDEMPVLE-----IPRKHQPSVPKAEEPLKTV 648
+++ AP+ + +K + D + E +P K + S PK E
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS-PKPESTCPLC 1062
Query: 649 QEKKKFRHRPEPLF---------IPPPPSYNPNPAASYSGATL---YQSQLRSPRVLGDH 696
+ + + P F + +NP P + L Q+Q LGD
Sbjct: 1063 KTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDI 1122
Query: 697 LLLDPTHELPPYTPPPM 713
+ P P +P P+
Sbjct: 1123 RKMPPAPSGPKASPMPV 1139
Score = 32.3 bits (72), Expect = 2.8
Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 274 QQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMM 333
++Q+ + ++E+Q+ Q + Q ++++ Q ++Q + Q Q Q Q +
Sbjct: 3246 REQEKIMVQKKLEELQSMKQHLLFQQ-----EEERQAQFMMRQETLAQQQLQLEQIQQLQ 3300
Query: 334 QHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLI 369
Q L +Q ++Q Q Y+ DP Q T Q I
Sbjct: 3301 QQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAI 3336
>gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3
[Homo sapiens]
Length = 837
Score = 65.5 bits (158), Expect = 3e-10
Identities = 114/461 (24%), Positives = 169/461 (36%), Gaps = 100/461 (21%)
Query: 252 QAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQP-------PP 304
Q Q L Q QQ+QQ Q QQQQ QQ + +Q++ QQ P P P PP
Sbjct: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLL---QQSPPQAPLPMAVSRGLPP 61
Query: 305 QQQQPQQLQLQ-QRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQA 363
QQ Q L LQ S+ Q ++Q LQ Q M PP+ +
Sbjct: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAM---PPATY-------DTAG 111
Query: 364 HTVQLIPLGSMSQYYYQEP--QQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLS 421
T+ LG++ Y P P P Q L+ + Q++
Sbjct: 112 LTMPTATLGNLRGYGMASPGLAAPSLTP----------PQLATPNLQQFFPQATRQSL-- 159
Query: 422 SHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQ-- 479
LGPP G+ ++PS +L+ PQ Q + S+ P
Sbjct: 160 ----LGPPPVGVP-------------------MNPSQFNLSGRNPQKQARTSSSTTPNRK 196
Query: 480 -MHLPDGRAQPGSPESSGQPKGAFGEQFD--------AKNKLTCS----ICLKEFKNLPA 526
M + D P E + +P+ E D AK K T + C E LPA
Sbjct: 197 TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC--EASELPA 254
Query: 527 LNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPV 586
+RS P K+ G+ + QPQ + P P LP E+L V+P
Sbjct: 255 --KRLRS----SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP---EALEAQVLPR 305
Query: 587 SVPVKLLPPKPSSQGFTNSTVAAPSARDKP-----ASSMSDDEMPVLEIPRKHQPSVPKA 641
P ++L + Q T + + + +P A + + E VL+ ++ QP + +
Sbjct: 306 FQP-RVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ-QKQVQPQLQQE 363
Query: 642 EEPLKTVQEK---------KKFRHRPEPLFIPPPPSYNPNP 673
EP K VQ + + H P + + PP + P
Sbjct: 364 AEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQP 404
Score = 60.8 bits (146), Expect = 7e-09
Identities = 55/221 (24%), Positives = 96/221 (43%), Gaps = 11/221 (4%)
Query: 160 NNMAQVLHTQSAVMDGAPDSALRQLLSQKPME-PPAPAIPSRYQQVPQ-QPHPGFTGGLS 217
N + +S +G+ ++A ++ + + + PP P ++ ++ P +P P L
Sbjct: 194 NRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELP 253
Query: 218 KPALQVGQHPTQGHLYYDYQ---QPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQ 274
L+ + PT+ Q QP A++ V + Q P +L + ++ ++ P
Sbjct: 254 AKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP--KQTQTPDLLPEALEAQVLPRFQPRVL 311
Query: 275 QQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQ 334
Q QA Q + I + Q++P + Q P+ L LQQ+Q Q+ Q +PQ +Q
Sbjct: 312 QVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQ 371
Query: 335 ---HLQEQQQQQMHLQPPS-YHRDPHQYTPEQAHTVQLIPL 371
H Q Q Q PP+ P + T EQ HT + L
Sbjct: 372 PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSL 412
>gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2
[Homo sapiens]
Length = 842
Score = 65.5 bits (158), Expect = 3e-10
Identities = 113/456 (24%), Positives = 171/456 (37%), Gaps = 85/456 (18%)
Query: 252 QAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQP-------PP 304
Q Q L Q QQ+QQ Q QQQQ QQ + +Q++ QQ P P P PP
Sbjct: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLL---QQSPPQAPLPMAVSRGLPP 61
Query: 305 QQQQPQQLQLQ-QRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQA 363
QQ Q L LQ S+ Q ++Q LQ Q M PP+ +
Sbjct: 62 QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAM---PPATY-------DTAG 111
Query: 364 HTVQLIPLGSMSQYYYQEP--QQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLS 421
T+ LG++ Y P P P Q L+ + Q++
Sbjct: 112 LTMPTATLGNLRGYGMASPGLAAPSLTP----------PQLATPNLQQFFPQATRQSL-- 159
Query: 422 SHGDLGPPDTGMG-DPASSDLT---------RVSSTLPHRPLLSPSGIHLNNMGPQHQQL 471
LGPP G+ +P+ +L+ SST P+R S + + + +
Sbjct: 160 ----LGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEG- 214
Query: 472 SPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHM 531
S A P+M P+ + P PE + K + A C E LPA +
Sbjct: 215 SEEAAEPRMDTPEDQDLPPCPEDIAKEK-----RTPAPEPEPC-----EASELPA--KRL 262
Query: 532 RSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVK 591
RS P K+ G+ + QPQ + P P LP E+L V+P P +
Sbjct: 263 RS----SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP---EALEAQVLPRFQP-R 314
Query: 592 LLPPKPSSQGFTNSTVAAPSARDKP-----ASSMSDDEMPVLEIPRKHQPSVPKAEEPLK 646
+L + Q T + + + +P A + + E VL+ ++ QP + + EP K
Sbjct: 315 VLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ-QKQVQPQLQQEAEPQK 373
Query: 647 TVQEK---------KKFRHRPEPLFIPPPPSYNPNP 673
VQ + + H P + + PP + P
Sbjct: 374 QVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQP 409
Score = 60.5 bits (145), Expect = 1e-08
Identities = 51/188 (27%), Positives = 81/188 (43%), Gaps = 10/188 (5%)
Query: 192 PPAPAIPSRYQQVPQ-QPHPGFTGGLSKPALQVGQHPTQGHLYYDYQ---QPLAQVPVQG 247
PP P ++ ++ P +P P L L+ + PT+ Q QP A++ V
Sbjct: 232 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP- 290
Query: 248 GQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQ 307
+ Q P +L + ++ ++ P Q QA Q + I + Q++P + Q
Sbjct: 291 -KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 349
Query: 308 QPQQLQLQQRQGSMQIPQYYQPQPMMQ---HLQEQQQQQMHLQPPS-YHRDPHQYTPEQA 363
P+ L LQQ+Q Q+ Q +PQ +Q H Q Q Q PP+ P + T EQ
Sbjct: 350 SPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQP 409
Query: 364 HTVQLIPL 371
HT + L
Sbjct: 410 HTQPQVSL 417
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 65.5 bits (158), Expect = 3e-10
Identities = 58/221 (26%), Positives = 83/221 (37%), Gaps = 52/221 (23%)
Query: 525 PALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVM 584
P L +HG R +P + P P PP PPPPPPP PP LP + TP+V
Sbjct: 150 PRLGNTSEAHGAARTAP-------PRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVS 202
Query: 585 P-----------VSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRK 633
P V+ PV PP P P+ P +S+ D+ ++
Sbjct: 203 PPGPLTKGNLPVVAPPVPCAPPPPPPP-------PPPTPPPLPPASVLSDKAVKPQLAPL 255
Query: 634 HQPSVPK-------------AEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGA 680
H P +P EP Q+ ++ P PL PP + +P AS
Sbjct: 256 HLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPL----PPYASCSPRAS---- 307
Query: 681 TLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGS 721
L +P + G + + LPP +P P + G+
Sbjct: 308 ------LPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGA 342
Score = 45.1 bits (105), Expect = 4e-04
Identities = 18/28 (64%), Positives = 19/28 (67%), Gaps = 5/28 (17%)
Query: 552 LPPQPQPPLPPPP-----PPPPPPQLPP 574
+PP P PPLPPPP PPPPPP PP
Sbjct: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAPP 30
Score = 39.7 bits (91), Expect = 0.017
Identities = 19/46 (41%), Positives = 22/46 (47%)
Query: 554 PQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSS 599
P P PP PP PPPPPP PP P V + ++ PK S
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRS 47
Score = 36.6 bits (83), Expect = 0.15
Identities = 16/28 (57%), Positives = 17/28 (60%), Gaps = 3/28 (10%)
Query: 552 LPPQPQPPLPPPPPPPP---PPQLPPEA 576
+P P PP P PPPPPP PP PP A
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSA 28
Score = 35.0 bits (79), Expect = 0.43
Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 4/93 (4%)
Query: 548 GEKVLPPQP----QPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFT 603
G K P P Q P PPPP PP P A P + V+ + PP P
Sbjct: 274 GLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSF 333
Query: 604 NSTVAAPSARDKPASSMSDDEMPVLEIPRKHQP 636
+ A+ PA P L+ R +P
Sbjct: 334 QAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRP 366
Score = 34.7 bits (78), Expect = 0.56
Identities = 56/225 (24%), Positives = 79/225 (35%), Gaps = 33/225 (14%)
Query: 560 LPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASS 619
+P PPPPPPP PP P+ P PP PS+ + T + A K S+
Sbjct: 1 MPVPPPPPPPLPPPPP---------PLGAPP---PPPPSAPPVSTDTSSLRRADPKGRSA 48
Query: 620 MSDDEM------PVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEP-----LFIPPPPS 668
+ D V +I + P + ++ K R P LF P
Sbjct: 49 LLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPV 108
Query: 669 YNPNPAASYSGATLYQ---SQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFS 725
P +G Q S+ SPR L + + P +PP + P L + G
Sbjct: 109 LRPAGQRDVAGGKTGQGPGSRAPSPR-LPNKTISGPL--IPPAS--PRLGNTSEAHGAAR 163
Query: 726 NVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTPGP 770
+ P P P P P P L S+S + + PGP
Sbjct: 164 TAPPRPNVPAPPPPTPPPPPPPLPPPL--PSSSPIKTPLVSPPGP 206
>gi|94721313 mesoderm induction early response 1, family member 3
[Homo sapiens]
Length = 549
Score = 65.5 bits (158), Expect = 3e-10
Identities = 55/176 (31%), Positives = 83/176 (47%), Gaps = 23/176 (13%)
Query: 771 GEQTVDVEPRINIGLRFQAEIP----ELQDISALAQDTHKATLVWKPWPELENHDLQQRV 826
G D+ I IGL++QAEIP E + ++ + L+W P LE+ + V
Sbjct: 166 GNSPEDLRKEIMIGLQYQAEIPPYLGEYDGNEKVYENEDQ--LLWCPDVVLESKVKEYLV 223
Query: 827 ENLLNLCCSSALP--GGGTNS---EFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLAN 881
E L + GT++ E AL+ L + ++ A+E R C+ A+
Sbjct: 224 ETSLRTGSEKIMDRISAGTHTRDNEQALYELLKCNHNIKEAIE--------RYCCNGKAS 275
Query: 882 YHYAGSDKWTSLERKLFNKALATYSKDFIFVQK-MVKSKTVAQCVEYYYTWKKIMR 936
G WT E + F AL + KDF +QK V+++TVA+CV +YY WKK R
Sbjct: 276 Q---GMTAWTEEECRSFEHALMLFGKDFHLIQKNKVRTRTVAECVAFYYMWKKSER 328
>gi|7661892 REST corepressor 1 [Homo sapiens]
Length = 482
Score = 65.1 bits (157), Expect = 4e-10
Identities = 60/221 (27%), Positives = 98/221 (44%), Gaps = 38/221 (17%)
Query: 781 INIGLRFQAEIPELQDISALAQDTHK----ATLVWKPWPELENHDLQQRVENLLNLCCSS 836
+ +G ++QA +P+ D + LA+ + + LVW P L L + + +
Sbjct: 102 MRVGPQYQAVVPDF-DPAKLARRSQERDNLGMLVWSPNQNLSEAKLDEYI--------AI 152
Query: 837 ALPGGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERK 896
A G N E AL LF K ++ +L L P D+WT ++
Sbjct: 153 AKEKHGYNMEQALGMLFWHKHNIEKSLADLPNFTPF--------------PDEWTVEDKV 198
Query: 897 LFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMR----LGRKHRTRLAEIIDDC 952
LF +A + + K F +Q+M+ K++A V++YY+WKK + R R + E
Sbjct: 199 LFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTRTKTSVMDRHARKQKRE----- 253
Query: 953 VTSEEEEELEEEEEEDP-EEDRKSTKEEESEVPKSPEPPPV 992
E E+ELEE +P + + KE + EVP + P V
Sbjct: 254 -REESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQV 293
Score = 38.1 bits (87), Expect = 0.051
Identities = 25/107 (23%), Positives = 48/107 (44%), Gaps = 14/107 (13%)
Query: 889 KWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEI 948
+WT+ E+ L +A+ Y +DF + ++ +K+V Q ++ +++ +
Sbjct: 382 RWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNI----------- 430
Query: 949 IDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVL 995
D V E E E +EE P ++K K ++ + E PVL
Sbjct: 431 --DEVLQEWEAEHGKEETNGP-SNQKPVKSPDNSIKMPEEEDEAPVL 474
>gi|209977084 REST corepressor 3 isoform c [Homo sapiens]
Length = 449
Score = 64.3 bits (155), Expect = 7e-10
Identities = 55/210 (26%), Positives = 92/210 (43%), Gaps = 28/210 (13%)
Query: 781 INIGLRFQAEIPELQDISALAQDTHKA-TLVWKPWPELENHDLQQRVENLLNLCCSSALP 839
+ +G +QA IPE + D LVW P+ + + L + + + A
Sbjct: 59 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYI--------AIAKE 110
Query: 840 GGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFN 899
G N E AL LF K ++ +L L P D+WT ++ LF
Sbjct: 111 KHGYNVEQALGMLFWHKHNIEKSLADLPNFTPF--------------PDEWTVEDKVLFE 156
Query: 900 KALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKI---MRLGRKHRTRLAEIIDDCVTSE 956
+A + + K F +Q+M+ KT+A V+YYY+WKK L + +LA + + +
Sbjct: 157 QAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDD 216
Query: 957 EEEELEEEEEEDPEED--RKSTKEEESEVP 984
+ EE + D + D +++ KE +E P
Sbjct: 217 DVEETHPMDGNDSDYDPKKEAKKEGNTEQP 246
Score = 35.0 bits (79), Expect = 0.43
Identities = 23/92 (25%), Positives = 40/92 (43%)
Query: 889 KWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEI 948
+WT+ E+ L + + Y KDF + ++ +KTV Q ++ +++ L + AE
Sbjct: 347 RWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 406
Query: 949 IDDCVTSEEEEELEEEEEEDPEEDRKSTKEEE 980
+ EE + KST EEE
Sbjct: 407 GTQASNGDASTLGEETKSASNVPSGKSTDEEE 438
>gi|209977080 REST corepressor 3 isoform a [Homo sapiens]
Length = 553
Score = 64.3 bits (155), Expect = 7e-10
Identities = 55/210 (26%), Positives = 92/210 (43%), Gaps = 28/210 (13%)
Query: 781 INIGLRFQAEIPELQDISALAQDTHKA-TLVWKPWPELENHDLQQRVENLLNLCCSSALP 839
+ +G +QA IPE + D LVW P+ + + L + + + A
Sbjct: 59 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYI--------AIAKE 110
Query: 840 GGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFN 899
G N E AL LF K ++ +L L P D+WT ++ LF
Sbjct: 111 KHGYNVEQALGMLFWHKHNIEKSLADLPNFTPF--------------PDEWTVEDKVLFE 156
Query: 900 KALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKI---MRLGRKHRTRLAEIIDDCVTSE 956
+A + + K F +Q+M+ KT+A V+YYY+WKK L + +LA + + +
Sbjct: 157 QAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDD 216
Query: 957 EEEELEEEEEEDPEED--RKSTKEEESEVP 984
+ EE + D + D +++ KE +E P
Sbjct: 217 DVEETHPMDGNDSDYDPKKEAKKEGNTEQP 246
Score = 52.4 bits (124), Expect = 3e-06
Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 5/152 (3%)
Query: 889 KWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEI 948
+WT+ E+ L + + Y KDF + ++ +KTV Q ++ +++ L + AE
Sbjct: 347 RWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 406
Query: 949 IDDCVTSEEEEELEEEEEEDPEEDRKST-KEEESEVPKSPE----PPPVPVLAPTEGPPL 1003
+ EE + KST +EEE++ P++P PP P PT P+
Sbjct: 407 GTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPI 466
Query: 1004 QALGQPSGSFICEMPNCGAVFSSRQALNGHAR 1035
L QP +P A+ L AR
Sbjct: 467 ATLNQPPPLLRPTLPAAPALHRQPPPLQQQAR 498
Score = 30.8 bits (68), Expect = 8.1
Identities = 30/127 (23%), Positives = 39/127 (30%), Gaps = 38/127 (29%)
Query: 556 PQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDK 615
PQ P P PP P P + + P P L P P AAP+ +
Sbjct: 443 PQAPRTLGPSPPAPSSTPTPTAPIATLNQP---PPLLRPTLP----------AAPALHRQ 489
Query: 616 PASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPP---PPSYNPN 672
P P ++ + +Q + P PL P PP NP
Sbjct: 490 P----------------------PPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPR 527
Query: 673 PAASYSG 679
P S G
Sbjct: 528 PVLSTVG 534
>gi|8922733 REST corepressor 3 isoform d [Homo sapiens]
Length = 495
Score = 64.3 bits (155), Expect = 7e-10
Identities = 55/210 (26%), Positives = 92/210 (43%), Gaps = 28/210 (13%)
Query: 781 INIGLRFQAEIPELQDISALAQDTHKA-TLVWKPWPELENHDLQQRVENLLNLCCSSALP 839
+ +G +QA IPE + D LVW P+ + + L + + + A
Sbjct: 1 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYI--------AIAKE 52
Query: 840 GGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFN 899
G N E AL LF K ++ +L L P D+WT ++ LF
Sbjct: 53 KHGYNVEQALGMLFWHKHNIEKSLADLPNFTPF--------------PDEWTVEDKVLFE 98
Query: 900 KALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKI---MRLGRKHRTRLAEIIDDCVTSE 956
+A + + K F +Q+M+ KT+A V+YYY+WKK L + +LA + + +
Sbjct: 99 QAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDD 158
Query: 957 EEEELEEEEEEDPEED--RKSTKEEESEVP 984
+ EE + D + D +++ KE +E P
Sbjct: 159 DVEETHPMDGNDSDYDPKKEAKKEGNTEQP 188
Score = 52.4 bits (124), Expect = 3e-06
Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 5/152 (3%)
Query: 889 KWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEI 948
+WT+ E+ L + + Y KDF + ++ +KTV Q ++ +++ L + AE
Sbjct: 289 RWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 348
Query: 949 IDDCVTSEEEEELEEEEEEDPEEDRKST-KEEESEVPKSPE----PPPVPVLAPTEGPPL 1003
+ EE + KST +EEE++ P++P PP P PT P+
Sbjct: 349 GTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPI 408
Query: 1004 QALGQPSGSFICEMPNCGAVFSSRQALNGHAR 1035
L QP +P A+ L AR
Sbjct: 409 ATLNQPPPLLRPTLPAAPALHRQPPPLQQQAR 440
Score = 30.8 bits (68), Expect = 8.1
Identities = 30/127 (23%), Positives = 39/127 (30%), Gaps = 38/127 (29%)
Query: 556 PQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDK 615
PQ P P PP P P + + P P L P P AAP+ +
Sbjct: 385 PQAPRTLGPSPPAPSSTPTPTAPIATLNQP---PPLLRPTLP----------AAPALHRQ 431
Query: 616 PASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPP---PPSYNPN 672
P P ++ + +Q + P PL P PP NP
Sbjct: 432 P----------------------PPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPR 469
Query: 673 PAASYSG 679
P S G
Sbjct: 470 PVLSTVG 476
>gi|209977082 REST corepressor 3 isoform b [Homo sapiens]
Length = 436
Score = 63.9 bits (154), Expect = 9e-10
Identities = 55/210 (26%), Positives = 92/210 (43%), Gaps = 28/210 (13%)
Query: 781 INIGLRFQAEIPELQDISALAQDTHKA-TLVWKPWPELENHDLQQRVENLLNLCCSSALP 839
+ +G +QA IPE + D LVW P+ + + L + + + A
Sbjct: 59 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDARLDEYI--------AIAKE 110
Query: 840 GGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFN 899
G N E AL LF K ++ +L L P D+WT ++ LF
Sbjct: 111 KHGYNVEQALGMLFWHKHNIEKSLADLPNFTPF--------------PDEWTVEDKVLFE 156
Query: 900 KALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKI---MRLGRKHRTRLAEIIDDCVTSE 956
+A + + K F +Q+M+ KT+A V+YYY+WKK L + +LA + + +
Sbjct: 157 QAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDD 216
Query: 957 EEEELEEEEEEDPEED--RKSTKEEESEVP 984
+ EE + D + D +++ KE +E P
Sbjct: 217 DVEETHPMDGNDSDYDPKKEAKKEGNTEQP 246
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 63.5 bits (153), Expect = 1e-09
Identities = 65/196 (33%), Positives = 80/196 (40%), Gaps = 23/196 (11%)
Query: 174 DGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLY 233
DG P + +S M P P + QQ+ QQ LS LQ Q +
Sbjct: 103 DGHPHNTFAVPVSVAMMTPQV-ITPQQMQQILQQQV------LSPQQLQALLQQQQAVM- 154
Query: 234 YDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQ 293
L Q +Q Q Q+ Q +QQ QQ Q QQQQQ QQ+ Q+ Q Q Q
Sbjct: 155 ------LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 208
Query: 294 QIRPSQPQPP--------PQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMH 345
Q + Q Q P QQQQ QQL QQ Q+ Q Q Q QHL Q+Q +
Sbjct: 209 QQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQ-QQQHLLSLQRQGLI 267
Query: 346 LQPPSYHRDPHQYTPE 361
PP P Q P+
Sbjct: 268 SIPPGQAALPVQSLPQ 283
Score = 63.2 bits (152), Expect = 1e-09
Identities = 63/203 (31%), Positives = 82/203 (40%), Gaps = 21/203 (10%)
Query: 213 TGGLSKPALQVGQHPTQ-----------GHLYYDYQQPLAQVPVQGGQPLQAPQMLS-QH 260
T GL P Q P Q GH D P V + PQ+++ Q
Sbjct: 70 TSGLKSPKSSDKQRPLQELLPETKLCICGHSSGD-GHPHNTFAVPVSVAMMTPQVITPQQ 128
Query: 261 MQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQI-RPSQPQPPPQQQQPQQLQLQQRQG 319
MQQ+ Q Q PQQ Q QQ+ ++ Q Q Q+ + Q Q Q Q QQ Q QQ+Q
Sbjct: 129 MQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQ 188
Query: 320 SMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYY 379
Q Q Q Q Q Q+QQQQQ Q P Q +Q + + Q +
Sbjct: 189 QQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQL------AAQQLVF 242
Query: 380 QEPQQPYSHPLYQQSHLSQHQQR 402
Q+ Q L QQ HL Q++
Sbjct: 243 QQ-QLLQMQQLQQQQHLLSLQRQ 264
Score = 57.8 bits (138), Expect = 6e-08
Identities = 65/231 (28%), Positives = 92/231 (39%), Gaps = 30/231 (12%)
Query: 238 QPLAQVPVQGGQPLQA--PQMLSQHMQQMQQHQYYPPQQQQ-------QAGQQRISMQEI 288
Q + Q V Q LQA Q + +QQ Q ++Y QQ+Q Q QQ+ Q+
Sbjct: 130 QQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQ 189
Query: 289 QTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQ--QQMHL 346
Q Q QQ + Q Q QQQQ QQ Q QQ G Q + Q Q Q L QQ QQ L
Sbjct: 190 QQQQQQQQQQQQQQQQQQQQQQQ-QQQQHPGK-QAKEQQQQQQQQQQLAAQQLVFQQQLL 247
Query: 347 QPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQ--SHLSQHQQRED 404
Q + H + ++ + IP G + PQ S QQ ++ ED
Sbjct: 248 QMQQLQQQQHLLSLQRQGLIS-IPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMED 306
Query: 405 SQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLS 455
+ +K HG L SS+ ++ S + H +++
Sbjct: 307 NGIK--------------HGGLDLTTNNSSSTTSSNTSKASPPITHHSIVN 343
Score = 55.1 bits (131), Expect = 4e-07
Identities = 45/124 (36%), Positives = 57/124 (45%), Gaps = 17/124 (13%)
Query: 292 PQQIRPSQPQPPPQQQ--QPQQLQ--LQQRQGSM----QIPQYYQPQPMMQHLQEQQQQQ 343
PQ I P Q Q QQQ PQQLQ LQQ+Q M Q+ ++Y+ Q HLQ QQQQ
Sbjct: 121 PQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180
Query: 344 MHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQRE 403
Q + Q +Q Q Q Q+ QQ HP +Q+ Q QQ++
Sbjct: 181 QQQQQQQQQQQQQQQQQQQQQQQQ--------QQQQQQQQQQQQHP-GKQAKEQQQQQQQ 231
Query: 404 DSQL 407
QL
Sbjct: 232 QQQL 235
Score = 53.1 bits (126), Expect = 2e-06
Identities = 52/169 (30%), Positives = 64/169 (37%), Gaps = 10/169 (5%)
Query: 181 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDY-QQP 239
++Q+L Q+ + P + QQ L + LQ Q L+ QQ
Sbjct: 129 MQQILQQQVLSPQQLQALLQQQQAVM---------LQQQQLQEFYKKQQEQLHLQLLQQQ 179
Query: 240 LAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQ 299
Q Q Q Q Q Q QQ QQ Q QQQQ G+Q Q+ Q Q QQ+ Q
Sbjct: 180 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 239
Query: 300 PQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQP 348
Q Q QQLQ QQ S+Q P L Q Q L P
Sbjct: 240 LVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 288
Score = 40.0 bits (92), Expect = 0.013
Identities = 35/123 (28%), Positives = 46/123 (37%), Gaps = 19/123 (15%)
Query: 307 QQPQQLQLQQRQGSMQIPQYYQPQP----MMQHLQE---QQQQQMHLQPPSYHRDPHQYT 359
QQ QQ+ QQ Q+ Q Q Q LQE +QQ+Q+HLQ + Q
Sbjct: 127 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
Query: 360 PEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAM 419
+Q Q Q+ QQ QQ Q QQ Q K +Q Q
Sbjct: 187 QQQ------------QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 234
Query: 420 LSS 422
L++
Sbjct: 235 LAA 237
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,232,768
Number of Sequences: 37866
Number of extensions: 4076149
Number of successful extensions: 103911
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1298
Number of HSP's successfully gapped in prelim test: 1632
Number of HSP's that attempted gapping in prelim test: 33842
Number of HSP's gapped (non-prelim): 38746
length of query: 1200
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1086
effective length of database: 13,930,794
effective search space: 15128842284
effective search space used: 15128842284
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.