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Search of human proteins with 157743257
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
(691 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 1355 0.0
gi|223890225 POU class 6 homeobox 1 [Homo sapiens] 317 2e-86
gi|170650730 pituitary specific transcription factor 1 isoform b... 119 9e-27
gi|4505955 pituitary specific transcription factor 1 isoform alp... 119 9e-27
gi|42476164 POU class 2 homeobox 1 [Homo sapiens] 116 6e-26
gi|148664218 POU transcription factor [Homo sapiens] 110 6e-24
gi|4505959 POU domain, class 2, transcription factor 2 [Homo sap... 105 1e-22
gi|110624763 POU domain, class 3, transcription factor 4 [Homo s... 105 1e-22
gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 105 2e-22
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa... 104 2e-22
gi|110624765 POU domain, class 3, transcription factor 1 [Homo s... 101 3e-21
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 99 1e-20
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens] 98 2e-20
gi|4505965 POU class 4 homeobox 3 [Homo sapiens] 94 3e-19
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 90 8e-18
gi|42560248 POU domain, class 5, transcription factor 1 isoform ... 87 7e-17
gi|116235491 POU domain, class 5, transcription factor 1 isoform... 86 2e-16
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 85 2e-16
gi|227430410 POU class 5 homeobox 1B [Homo sapiens] 83 1e-15
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 76 1e-13
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 75 3e-13
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 75 3e-13
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 74 3e-13
gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens] 74 5e-13
gi|56549696 E1A binding protein p400 [Homo sapiens] 74 6e-13
gi|150170670 piccolo isoform 2 [Homo sapiens] 72 1e-12
gi|150378539 piccolo isoform 1 [Homo sapiens] 72 1e-12
gi|238859557 regulatory factor X1 [Homo sapiens] 71 4e-12
gi|226246533 TOX high mobility group box family member 3 isoform... 71 4e-12
gi|226054295 TOX high mobility group box family member 3 isoform... 71 4e-12
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 1355 bits (3508), Expect = 0.0
Identities = 691/691 (100%), Positives = 691/691 (100%)
Query: 1 MSALLQDPMIAGQVSKPLLSVRSEMNAELRGEDKAATSDSELNEPLLAPVESNDSEDTPS 60
MSALLQDPMIAGQVSKPLLSVRSEMNAELRGEDKAATSDSELNEPLLAPVESNDSEDTPS
Sbjct: 1 MSALLQDPMIAGQVSKPLLSVRSEMNAELRGEDKAATSDSELNEPLLAPVESNDSEDTPS 60
Query: 61 KLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQP 120
KLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQP
Sbjct: 61 KLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQP 120
Query: 121 ILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQ 180
ILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQ
Sbjct: 121 ILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQ 180
Query: 181 QLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTS 240
QLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTS
Sbjct: 181 QLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTS 240
Query: 241 QLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNP 300
QLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNP
Sbjct: 241 QLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNP 300
Query: 301 LASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAA 360
LASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAA
Sbjct: 301 LASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAA 360
Query: 361 SGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSV 420
SGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSV
Sbjct: 361 SGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSV 420
Query: 421 GQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVN 480
GQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVN
Sbjct: 421 GQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVN 480
Query: 481 LEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQE 540
LEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQE
Sbjct: 481 LEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQE 540
Query: 541 NTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFI 600
NTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFI
Sbjct: 541 NTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFI 600
Query: 601 GSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQ 660
GSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQ
Sbjct: 601 GSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQ 660
Query: 661 ALKNTIKRLKQHEPATAVPLEPLTDSLEENS 691
ALKNTIKRLKQHEPATAVPLEPLTDSLEENS
Sbjct: 661 ALKNTIKRLKQHEPATAVPLEPLTDSLEENS 691
>gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
Length = 301
Score = 317 bits (812), Expect = 2e-86
Identities = 183/345 (53%), Positives = 221/345 (64%), Gaps = 56/345 (16%)
Query: 328 LQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATV 387
+ G++ Q++TNAQGQ+IGT+P + N S A + Q LQVQ +TPQLL NAQGQ+IAT+
Sbjct: 1 MPGISSQILTNAQGQVIGTLPWVVNSA-SVAAPAPAQSLQVQAVTPQLLLNAQGQVIATL 59
Query: 388 IGNQILP--VINTQGITLSPIKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVR 445
+ + P + SP K Q QP+ T A + SP
Sbjct: 60 ASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPT--------------VPQPAVVIASPAP 105
Query: 446 QASSSSSSS---SSSSALSVGQLVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQ 502
A S+S+ + S +V QLVS P T + + DG+NLEEIREFAK FKIRRLSLGLTQ
Sbjct: 106 AAKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQ 165
Query: 503 TQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFE 562
TQVGQAL+ATEGPAYSQSAICR FE
Sbjct: 166 TQVGQALTATEGPAYSQSAICR------------------------------------FE 189
Query: 563 KLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFIGSEPSKKRKRRTSFTPQALEIL 622
KLDITPKSAQK+KPVLE+W+ EAE R++ G QNL EF+G EPSKKRKRRTSFTPQA+E L
Sbjct: 190 KLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEAL 249
Query: 623 NAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNTIK 667
NA+FEKN P+GQE+TEIA++LNYDREVVRVWFCN+RQ LKNT K
Sbjct: 250 NAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSK 294
Score = 43.1 bits (100), Expect = 9e-04
Identities = 31/101 (30%), Positives = 43/101 (42%), Gaps = 6/101 (5%)
Query: 146 LTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQ-----QQQQQPPPS 200
LTN QG V + + + SL Q QL L Q Q PPP
Sbjct: 9 LTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPV 68
Query: 201 TNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQ 241
+ P P++P++S+ QP+QPTP P PAP ++
Sbjct: 69 AVRKPS-TPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAK 108
Score = 35.0 bits (79), Expect = 0.23
Identities = 33/108 (30%), Positives = 44/108 (40%), Gaps = 14/108 (12%)
Query: 198 PPSTNQHPQPAPQAPSQSQQQPLQP--TPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHS 255
P + Q PQ +Q Q + + P PP A ++P P S + QP Q P
Sbjct: 34 PAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTP-- 91
Query: 256 HSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLT---PPNPLQLVNNP 300
QP+ S +P KPS S P P+T P QLV+ P
Sbjct: 92 ---TVPQPAVVIASPAPAAKPSAS----APIPITCSETPTVSQLVSKP 132
>gi|170650730 pituitary specific transcription factor 1 isoform beta
[Homo sapiens]
Length = 317
Score = 119 bits (298), Expect = 9e-27
Identities = 71/197 (36%), Positives = 103/197 (52%), Gaps = 41/197 (20%)
Query: 475 EVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFL 534
++D + E+ +FA FK+RR+ LG TQT VG+AL+A G +SQ+ ICR
Sbjct: 149 DMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICR---------- 198
Query: 535 PQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQ 594
FE L ++ K+A K+K +L +W+ EAE +
Sbjct: 199 --------------------------FENLQLSFKNACKLKAILSKWLEEAE--QVGALY 230
Query: 595 NLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVW 654
N E +G+ +KRKRRT+ + A + L HF + PS QE+ +AE+LN ++EVVRVW
Sbjct: 231 N--EKVGAN-ERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVW 287
Query: 655 FCNKRQALKNTIKRLKQ 671
FCN+RQ K L Q
Sbjct: 288 FCNRRQREKRVKTSLNQ 304
>gi|4505955 pituitary specific transcription factor 1 isoform alpha
[Homo sapiens]
Length = 291
Score = 119 bits (298), Expect = 9e-27
Identities = 71/197 (36%), Positives = 103/197 (52%), Gaps = 41/197 (20%)
Query: 475 EVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFL 534
++D + E+ +FA FK+RR+ LG TQT VG+AL+A G +SQ+ ICR
Sbjct: 123 DMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICR---------- 172
Query: 535 PQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQ 594
FE L ++ K+A K+K +L +W+ EAE +
Sbjct: 173 --------------------------FENLQLSFKNACKLKAILSKWLEEAE--QVGALY 204
Query: 595 NLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVW 654
N E +G+ +KRKRRT+ + A + L HF + PS QE+ +AE+LN ++EVVRVW
Sbjct: 205 N--EKVGAN-ERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVW 261
Query: 655 FCNKRQALKNTIKRLKQ 671
FCN+RQ K L Q
Sbjct: 262 FCNRRQREKRVKTSLNQ 278
>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
Length = 743
Score = 116 bits (291), Expect = 6e-26
Identities = 117/443 (26%), Positives = 182/443 (41%), Gaps = 85/443 (19%)
Query: 240 SQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSP------PQKPSQSPGHGLPSPLTPPNP 293
+ LQ A Q Q S+ ++ + P+Q S P PQ G + P
Sbjct: 59 TSLQAAAQSLNVQSKSNEESGDSQQPSQPSQQPSVQAAIPQTQLMLAGGQITGLTLTPAQ 118
Query: 294 LQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNP 353
QL+ +QA AAA+ ++SQ A +++ +T
Sbjct: 119 QQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATPMTQI-------------- 164
Query: 354 GPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQG--ITLSPIKPGQQ 411
P SQ Q LQ Q N Q ++ + P N Q +S GQQ
Sbjct: 165 -PLSQPIQIAQDLQQLQQLQQQNLNLQQFVL-------VHPTTNLQPAQFIISQTPQGQQ 216
Query: 412 LHQPSQTSVGQAASQGNLLHLAHSQASMSQS-PVRQASSSSSSSSSSSALSVGQLVSNPQ 470
+Q + Q Q SQA++ QS P +S ++ + + A + Q + Q
Sbjct: 217 GLLQAQNLLTQLPQQ--------SQANLLQSQPSITLTSQPATPTRTIAATPIQTLPQSQ 268
Query: 471 TAAGEVDGVNLEE------IREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICR 524
+ +D +LEE + +FAK FK RR+ LG TQ VG A+ G +SQ+ I
Sbjct: 269 STPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTI-- 326
Query: 525 HTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAE 584
+RFE L+++ K+ K+KP+LE+W+ +
Sbjct: 327 ----------------------------------SRFEALNLSFKNMCKLKPLLEKWLND 352
Query: 585 AEARHRAGMQNLTEFIGSEP----SKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEI 640
AE + + S S++RK+RTS L F +N P+ +E+T I
Sbjct: 353 AENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMI 412
Query: 641 AEKLNYDREVVRVWFCNKRQALK 663
A++LN ++EV+RVWFCN+RQ K
Sbjct: 413 ADQLNMEKEVIRVWFCNRRQKEK 435
Score = 37.4 bits (85), Expect = 0.047
Identities = 48/176 (27%), Positives = 65/176 (36%), Gaps = 34/176 (19%)
Query: 79 QHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPFNMAG--QLGGQ-- 134
QH ASQ H +A + + P L+QPI I ++ QL Q
Sbjct: 139 QHSASQQH-----------SAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNL 187
Query: 135 --QGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQ 192
Q VL PT NL Q +++ G L QNL QL QQ Q
Sbjct: 188 NLQQFVLVHPTTNLQPAQFIISQTPQGQQGLLQAQNLLT-------------QLPQQSQA 234
Query: 193 QQQQPPPSTNQHPQPAPQ----APSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQ 244
Q PS QPA A + Q P + P++ S + P+ +L+Q
Sbjct: 235 NLLQSQPSITLTSQPATPTRTIAATPIQTLPQSQSTPKRIDTPSLEEPSDLEELEQ 290
Score = 32.7 bits (73), Expect = 1.2
Identities = 72/343 (20%), Positives = 127/343 (37%), Gaps = 68/343 (19%)
Query: 175 LNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQ 234
LN + + +++ ++Q++++ PPS+ +A S + TP A+
Sbjct: 416 LNMEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPTSLVATTPSLVTSSAATT 475
Query: 235 -PPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNP 293
+P L A + N + T S++PP S +T P+
Sbjct: 476 LTVSPVLPLTSAAVTNLSVTGTSDTTSNNTA-TVISTAPPAS----------SAVTSPS- 523
Query: 294 LQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQG---------QII 344
L +P AS + + A++ S +++Q LSS G T Q++ A G Q
Sbjct: 524 --LSPSPSASASTSEASSASETSTTQTTSTPLSSPLG-TSQVMVTASGLQTAAAAALQGA 580
Query: 345 GTIP-------------LMPNPGPSSQAASGTQGLQVQP------ITPQLLTNAQGQIIA 385
+P L P+ SQ A+G L + P ++P L++N+ I
Sbjct: 581 AQLPANASLAAMAAAAGLNPSLMAPSQFAAGGALLSLNPGTLSGALSPALMSNSTLATIQ 640
Query: 386 TVIGNQILPV-------------------INTQGITLSPIKPGQQLHQPSQTSVGQAASQ 426
+ LP+ I T + L+P P AAS
Sbjct: 641 ALASGGSLPITSLDATGNLVFANAGGAPNIVTAPLFLNPQNLSLLTSNPVSLVSAAAASA 700
Query: 427 GN-----LLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQ 464
GN LH + A Q+ + +S+S ++S+++ S Q
Sbjct: 701 GNSAPVASLHATSTSAESIQNSLFTVASASGAASTTTTASKAQ 743
Score = 30.0 bits (66), Expect = 7.5
Identities = 45/177 (25%), Positives = 59/177 (33%), Gaps = 29/177 (16%)
Query: 144 ANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPST-- 201
A + Q ++A G+ P Q +Q Q L +QQ QQ +T
Sbjct: 95 AAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATIS 154
Query: 202 -------NQHPQPAP-------QAPSQSQQQPL--------QPTPPQQPPP-ASQQPPAP 238
Q P P Q Q QQQ L PT QP Q P
Sbjct: 155 ASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHPTTNLQPAQFIISQTPQG 214
Query: 239 TSQLQQAPQPQQHQPHSHSQN--QNQPS--PTQQSSSPPQKPSQSPGHGLPSPLTPP 291
L QA P N Q+QPS T Q ++P + + +P LP + P
Sbjct: 215 QQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPIQTLPQSQSTP 271
>gi|148664218 POU transcription factor [Homo sapiens]
Length = 436
Score = 110 bits (274), Expect = 6e-24
Identities = 97/349 (27%), Positives = 156/349 (44%), Gaps = 56/349 (16%)
Query: 323 NALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQ 382
N L + + + ++++ Q + P + GP+ + + GL P + Q
Sbjct: 37 NGLDFNRQIKTEDLSDSLQQTLSHRPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQ 96
Query: 383 IIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQS 442
++ V G+ + + LS +PGQQ QP+ Q S L AS +
Sbjct: 97 LVL-VPGH----LQSVSQFLLSQTQPGQQGLQPNLLPFPQQQSGLLLPQTGPGLASQAFG 151
Query: 443 -PVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLT 501
P SS +S L V + + + + G + +LEE+ +FAK FK RR+ LG T
Sbjct: 152 HPGLPGSSLEPHLEASQHLPVPKHLPS---SGGADEPSDLEELEKFAKTFKQRRIKLGFT 208
Query: 502 QTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARF 561
Q VG A+ G +SQ+ I +RF
Sbjct: 209 QGDVGLAMGKLYGNDFSQTTI------------------------------------SRF 232
Query: 562 EKLDITPKSAQKIKPVLERWMAEAEARHR-------AGMQNLTEFIGSEPSKKRKRRTSF 614
E L+++ K+ K+KP+LE+W+ +AE+ + +L+E G +KRK+RTS
Sbjct: 233 EALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFG----RKRKKRTSI 288
Query: 615 TPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALK 663
L F+ N PS +E++ IAE+L+ ++EVVRVWFCN+RQ K
Sbjct: 289 ETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEK 337
>gi|4505959 POU domain, class 2, transcription factor 2 [Homo
sapiens]
Length = 463
Score = 105 bits (263), Expect = 1e-22
Identities = 101/363 (27%), Positives = 159/363 (43%), Gaps = 70/363 (19%)
Query: 337 TNAQGQIIGTIPLMPNP-GPSSQAA----SGTQG----LQVQPITPQLLTNAQGQIIATV 387
TN Q T P +P GPS++ SG L QP P L AQ + +
Sbjct: 40 TNHQNPQNKTSPFSVSPTGPSTKIKAEDPSGDSAPAAPLPPQPAQPHL-PQAQLMLTGSQ 98
Query: 388 IGNQILPVINTQGITLSPIKPGQQLHQPSQTSVGQAA-SQGNLLHLAHSQASMSQSPVRQ 446
+ I ++ Q + L P G L P+Q + QA SQ LL + Q+
Sbjct: 99 LAGDIQQLLQLQQLVLVP---GHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGAL 155
Query: 447 ASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVG 506
+S + + + S+P+ + +LEE+ +FA+ FK RR+ LG TQ VG
Sbjct: 156 LTSQPRAGLPTQPPKCLEPPSHPEEPS------DLEELEQFARTFKQRRIKLGFTQGDVG 209
Query: 507 QALSATEGPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDI 566
A+ G +SQ+ I +RFE L++
Sbjct: 210 LAMGKLYGNDFSQTTI------------------------------------SRFEALNL 233
Query: 567 TPKSAQKIKPVLERWMAEAEARH-----RAGMQNLTEFIGSE--PSKKRKRRTSFTPQAL 619
+ K+ K+KP+LE+W+ +AE + Q + +G + P ++RK+RTS
Sbjct: 234 SFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVR 293
Query: 620 EILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNTIKRLKQHEPATAVP 679
L F N P+ +E+ IAE+L+ ++EV+RVWFCN+RQ + K+ P +A P
Sbjct: 294 FALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQ-------KEKRINPCSAAP 346
Query: 680 LEP 682
+ P
Sbjct: 347 MLP 349
Score = 37.0 bits (84), Expect = 0.061
Identities = 57/208 (27%), Positives = 78/208 (37%), Gaps = 36/208 (17%)
Query: 42 LNEPLLAPVESNDSEDTPSKLFGARGNPALSDPGTPDQHQASQTHP--PFPVGPQPLLTA 99
+++PL A + DS PS+ N P T Q+ ++T P P GP + A
Sbjct: 13 MSKPLEAEKQGLDS---PSEHTDTERN----GPDTNHQNPQNKTSPFSVSPTGPSTKIKA 65
Query: 100 QQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAG 159
+ + A P PP QP LP A L L + AG
Sbjct: 66 EDPSGDSAPAAPL-PPQPAQP-------------------HLPQAQLM----LTGSQLAG 101
Query: 160 GIMTL-PLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQ 218
I L LQ L + Q L Q QQ Q P P+ Q PQ A SQ +
Sbjct: 102 DIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPR 161
Query: 219 PLQPTPPQQ--PPPASQQPPAPTSQLQQ 244
PT P + PP+ + P+ +L+Q
Sbjct: 162 AGLPTQPPKCLEPPSHPEEPSDLEELEQ 189
>gi|110624763 POU domain, class 3, transcription factor 4 [Homo
sapiens]
Length = 361
Score = 105 bits (263), Expect = 1e-22
Identities = 77/259 (29%), Positives = 120/259 (46%), Gaps = 56/259 (21%)
Query: 415 PSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSV----------GQ 464
PS TS GQ + +SQ + S + + + +++SA S+ G+
Sbjct: 122 PSITSSGQPLN-------VYSQPGFTVSGMLEHGGLTPPPAAASAQSLHPVLREPPDHGE 174
Query: 465 LVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICR 524
L S+ + + +E+ +FAK FK RR+ LG TQ VG AL G +SQ+ ICR
Sbjct: 175 LGSHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICR 234
Query: 525 HTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAE 584
FE L ++ K+ K+KP+L +W+ E
Sbjct: 235 ------------------------------------FEGLQLSFKNMCKLKPLLNKWLEE 258
Query: 585 AEARHRAGMQNLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKL 644
A++ G + I ++ +KRK+RTS +L HF K P+ QE++ +A+ L
Sbjct: 259 ADSS--TGSPTSIDKIAAQ-GRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSL 315
Query: 645 NYDREVVRVWFCNKRQALK 663
++EVVRVWFCN+RQ K
Sbjct: 316 QLEKEVVRVWFCNRRQKEK 334
>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
Length = 500
Score = 105 bits (261), Expect = 2e-22
Identities = 68/208 (32%), Positives = 99/208 (47%), Gaps = 40/208 (19%)
Query: 468 NPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTI 527
N + D +++ +FAK FK RR+ LG TQ VG AL G +SQ+ ICR
Sbjct: 306 NSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICR--- 362
Query: 528 LRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEA 587
FE L ++ K+ K+KP+L +W+ EA++
Sbjct: 363 ---------------------------------FEALQLSFKNMCKLKPLLNKWLEEADS 389
Query: 588 RHRAGMQNLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYD 647
G + I ++ +KRK+RTS L +HF K PS QE+T +A+ L +
Sbjct: 390 S--TGSPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLE 446
Query: 648 REVVRVWFCNKRQALKN-TIKRLKQHEP 674
+EVVRVWFCN+RQ K T ++Q P
Sbjct: 447 KEVVRVWFCNRRQKEKRMTPPGIQQQTP 474
Score = 33.5 bits (75), Expect = 0.68
Identities = 34/124 (27%), Positives = 46/124 (37%), Gaps = 20/124 (16%)
Query: 267 QQSSSPPQKPSQSPG-----------------HGLPSPLTPPNPLQLVNNPLASQAAAAA 309
QQ PP P Q P H P L PP P +P AAAAA
Sbjct: 134 QQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAA 193
Query: 310 AAMSSIASSQAFGNALSSLQGVTGQLVTNAQG---QIIGTIPLMPNPGPSSQAASGTQGL 366
AA ++ A++ A +++ Q Q + +Q + G + P PG A G
Sbjct: 194 AAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQS 253
Query: 367 QVQP 370
V P
Sbjct: 254 LVHP 257
>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
sapiens]
Length = 443
Score = 104 bits (260), Expect = 2e-22
Identities = 63/182 (34%), Positives = 92/182 (50%), Gaps = 39/182 (21%)
Query: 482 EEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQEN 541
+++ +FAK FK RR+ LG TQ VG AL G +SQ+ ICR
Sbjct: 268 DDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICR----------------- 310
Query: 542 TIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFIG 601
FE L ++ K+ K+KP+L +W+ EA++ +G + I
Sbjct: 311 -------------------FEALQLSFKNMCKLKPLLNKWLEEADSS--SGSPTSIDKIA 349
Query: 602 SEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQA 661
++ +KRK+RTS L +HF K PS QE+T +A+ L ++EVVRVWFCN+RQ
Sbjct: 350 AQ-GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQK 408
Query: 662 LK 663
K
Sbjct: 409 EK 410
Score = 48.9 bits (115), Expect = 2e-05
Identities = 43/127 (33%), Positives = 45/127 (35%), Gaps = 27/127 (21%)
Query: 178 QLQQLQLQLQQQQQQQQQQPPP-----STNQHPQPA-----------PQAPSQSQQQPLQ 221
Q QQ Q Q QQQQQQQQQQ PP + N HP P P + S L
Sbjct: 131 QQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGASNGGLLY 190
Query: 222 PTPP---QQPPPASQQPPA----PTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQ 274
P A QP P H PH HS QP P PPQ
Sbjct: 191 SQPSFTVNGMLGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPP----PPPPQ 246
Query: 275 KPSQSPG 281
P PG
Sbjct: 247 GPPGHPG 253
>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
sapiens]
Length = 451
Score = 101 bits (251), Expect = 3e-21
Identities = 66/209 (31%), Positives = 99/209 (47%), Gaps = 46/209 (22%)
Query: 477 DGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQ 536
D + +++ +FAK FK RR+ LG TQ VG AL G +SQ+ ICR
Sbjct: 248 DAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICR------------ 295
Query: 537 EAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNL 596
FE L ++ K+ K+KP+L +W+ E ++ +G
Sbjct: 296 ------------------------FEALQLSFKNMCKLKPLLNKWLEETDSS--SGSPTN 329
Query: 597 TEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFC 656
+ I ++ +KRK+RTS L +HF K PS E+T +A+ L ++EVVRVWFC
Sbjct: 330 LDKIAAQ-GRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFC 388
Query: 657 NKRQALKNTIKRLKQHEPATAVPLEPLTD 685
N+RQ + K+ PA P+ D
Sbjct: 389 NRRQ-------KEKRMTPAAGAGHPPMDD 410
>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
sapiens]
Length = 419
Score = 99.4 bits (246), Expect = 1e-20
Identities = 75/256 (29%), Positives = 114/256 (44%), Gaps = 59/256 (23%)
Query: 428 NLLHLAHSQASMSQS-------PVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVN 480
+L HL+H A+ + + P A+++ +++++A + V+ AA V
Sbjct: 195 SLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAG 254
Query: 481 L----------EEIREFAKAFKIRRLSLGLTQTQVGQALSATEGP---AYSQSAICRHTI 527
L E+ FA+ FK RR+ LG+TQ VG AL+ + P + SQS ICR
Sbjct: 255 LASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICR--- 311
Query: 528 LRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEA 587
FE L ++ + +KP+L+ W+ EAE
Sbjct: 312 ---------------------------------FESLTLSHNNMIALKPILQAWLEEAEG 338
Query: 588 RHRAGMQNLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYD 647
R M F G E K+++RTS L A+F PS +++ IAEKL+
Sbjct: 339 AQREKMNKPELFNGGE---KKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLK 395
Query: 648 REVVRVWFCNKRQALK 663
+ VVRVWFCN+RQ K
Sbjct: 396 KNVVRVWFCNQRQKQK 411
>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
Length = 409
Score = 98.2 bits (243), Expect = 2e-20
Identities = 77/260 (29%), Positives = 116/260 (44%), Gaps = 49/260 (18%)
Query: 413 HQPSQTSVGQAA---SQGNLLH-LAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSN 468
HQP Q G+ S G L +A ++ +P ++ + +ALS+
Sbjct: 182 HQPHQALEGELLEHLSPGLALGAMAGPDGAVVSTPAHAPHMATMNPMHQAALSMAHAHGL 241
Query: 469 PQTAA--GEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGP---AYSQSAIC 523
P +VD + ++ FA+ FK RR+ LG+TQ VG AL+ + P + SQS IC
Sbjct: 242 PSHMGCMSDVDA-DPRDLEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTIC 300
Query: 524 RHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMA 583
R FE L ++ + +KP+L+ W+
Sbjct: 301 R------------------------------------FESLTLSHNNMIALKPILQAWLE 324
Query: 584 EAEARHRAGMQNLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEK 643
EAE HR + F G+E K+++RTS L A+F PS +++ IAEK
Sbjct: 325 EAEKSHREKLTKPELFNGAE---KKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEK 381
Query: 644 LNYDREVVRVWFCNKRQALK 663
L+ + VVRVWFCN+RQ K
Sbjct: 382 LDLKKNVVRVWFCNQRQKQK 401
>gi|4505965 POU class 4 homeobox 3 [Homo sapiens]
Length = 338
Score = 94.4 bits (233), Expect = 3e-19
Identities = 63/184 (34%), Positives = 88/184 (47%), Gaps = 42/184 (22%)
Query: 483 EIREFAKAFKIRRLSLGLTQTQVGQALSATEGP---AYSQSAICRHTILRSHFFLPQEAQ 539
E+ FA+ FK RR+ LG+TQ VG AL+ + P + SQS ICR
Sbjct: 186 ELEAFAERFKQRRIKLGVTQADVGAALANLKIPGVGSLSQSTICR--------------- 230
Query: 540 ENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEF 599
FE L ++ + +KPVL+ W+ EAEA +R F
Sbjct: 231 ---------------------FESLTLSHNNMIALKPVLQAWLEEAEAAYREKNSKPELF 269
Query: 600 IGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKR 659
GSE ++++RTS L A+F PS +++ IAEKL+ + VVRVWFCN+R
Sbjct: 270 NGSE---RKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQR 326
Query: 660 QALK 663
Q K
Sbjct: 327 QKQK 330
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 89.7 bits (221), Expect = 8e-18
Identities = 110/360 (30%), Positives = 148/360 (41%), Gaps = 54/360 (15%)
Query: 161 IMTLPLQNLQATSSLNSQLQQL-QLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQP 219
++ L QN Q QLQ++ QLQLQQQQQQQQQQ Q QQQ
Sbjct: 220 LIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ----------------QQQQQQA 263
Query: 220 LQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSP---TQQSSSPPQKP 276
LQ PP Q PP Q P P+ L Q Q H H Q Q P Q S PPQ
Sbjct: 264 LQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQ 323
Query: 277 SQ---SPGHGLPSPL--TPPNPLQLVNNPLASQAAAAAAAM----SSIASSQAFGNALSS 327
+Q S LP + T P PL+ V P+ Q + +++ ++QA
Sbjct: 324 TQPLVSQAQALPGQMLYTQP-PLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPG 382
Query: 328 LQGVTGQLVTNAQGQIIGTIPLMPNPG----PSSQAASGTQGL-QV-QPITPQLLTNAQG 381
+Q +T L AQG + P PSS G Q + QV Q P L + + G
Sbjct: 383 VQMITEAL---AQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPG 439
Query: 382 QIIATVIGNQILPVINTQGITLSPIKPGQQLHQP-SQTSVGQAASQGNLLHLAHSQASMS 440
Q + T P + Q PGQ QP S S G A S + L Q S
Sbjct: 440 QQVQTPQSMPPPPQPSPQ--------PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQP--S 489
Query: 441 QSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVN---LEEIREFAKAFK-IRRL 496
QSPV + + S S L+ S+ + AG L+++++ +K + +RR+
Sbjct: 490 QSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRM 549
Score = 67.8 bits (164), Expect = 3e-11
Identities = 105/398 (26%), Positives = 141/398 (35%), Gaps = 39/398 (9%)
Query: 110 MPGGPPA----LNQPILIPFNMAGQLG--GQQGLVLTLPTANLTNIQGLVAAAAAGGIMT 163
+ GGP A + P P G +G G G ++L G+ + A
Sbjct: 88 LTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTA 147
Query: 164 LPLQNLQATS-SLNSQLQQLQLQ------LQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQ 216
P LQ +L Q QQ Q Q LQQQQQQQQQQ + Q QA Q Q
Sbjct: 148 TPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQ 207
Query: 217 QQPLQPTPPQQ-----PPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSS 271
QQ Q QQ QQ QLQ+ Q Q Q Q Q Q +
Sbjct: 208 QQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ 267
Query: 272 PP------QKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNAL 325
PP Q+P P LP L + Q P Q A S Q+ L
Sbjct: 268 PPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPL 327
Query: 326 -SSLQGVTGQLVTN-------AQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLT 377
S Q + GQ++ ++ P+ P A Q Q+ Q++T
Sbjct: 328 VSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMIT 387
Query: 378 NAQGQIIATVIGNQILPVINTQGITLSPIKPGQQ-LHQPSQTSVG--QAASQGNLLHLAH 434
A Q I + P I S I G+Q + Q SQ+S+ + S G +
Sbjct: 388 EALAQ-GGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQ 446
Query: 435 SQ---ASMSQSPVRQASSSSSSSSSSSALSVGQLVSNP 469
S S P + +S +S+ SS A S + +P
Sbjct: 447 SMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSP 484
Score = 33.1 bits (74), Expect = 0.88
Identities = 42/190 (22%), Positives = 67/190 (35%), Gaps = 10/190 (5%)
Query: 69 PALSDPGTPDQHQASQTHPPFP-VGPQPLLTAQQLASAV-AGVMPGGPPALNQPILIPFN 126
P LS P Q Q Q+ PP P PQP + Q S V +G P L P P
Sbjct: 431 PMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ 490
Query: 127 MAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQL 186
Q + P T + + AG Q L L+ ++ L+ +
Sbjct: 491 SPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMI 550
Query: 187 QQQQQQQQQQPPPSTNQH-----PQPAPQAPSQSQQQ---PLQPTPPQQPPPASQQPPAP 238
+ + + ++ S + P+ + P ++ Q+ L+ P PP P
Sbjct: 551 NKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVP 610
Query: 239 TSQLQQAPQP 248
++ Q QP
Sbjct: 611 PTKQQYLCQP 620
>gi|42560248 POU domain, class 5, transcription factor 1 isoform 1
[Homo sapiens]
Length = 360
Score = 86.7 bits (213), Expect = 7e-17
Identities = 84/342 (24%), Positives = 139/342 (40%), Gaps = 57/342 (16%)
Query: 341 GQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQG 400
G + P PG G + V P T + QG IG + P G
Sbjct: 3 GHLASDFAFSPPPGGGGDGPGGPEPGWVDPRT---WLSFQGPPGGPGIGPGVGPGSEVWG 59
Query: 401 ITLSPIKP-----GQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSS 455
I P P G + Q VG G +A + +S +
Sbjct: 60 IP--PCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTV 117
Query: 456 SSSALSVGQ--LVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATE 513
+ A+ + + L NP+ + ++ + +E+ +FAK K +R++LG TQ VG L
Sbjct: 118 TPGAVKLEKEKLEQNPEESQ-DIKALQ-KELEQFAKLLKQKRITLGYTQADVGLTLGVLF 175
Query: 514 GPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQK 573
G +SQ+ ICR FE L ++ K+ K
Sbjct: 176 GKVFSQTTICR------------------------------------FEALQLSFKNMCK 199
Query: 574 IKPVLERWMAEAEARHRAGMQNLTEFIGSEP--SKKRKRRTSFTPQALEILNAHFEKNTH 631
++P+L++W+ EA+ +NL E +E ++++RTS + L F +
Sbjct: 200 LRPLLQKWVEEADNN-----ENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPK 254
Query: 632 PSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNTIKRLKQHE 673
P+ Q+++ IA++L +++VVRVWFCN+RQ K + Q E
Sbjct: 255 PTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQRE 296
>gi|116235491 POU domain, class 5, transcription factor 1 isoform 2
[Homo sapiens]
Length = 265
Score = 85.5 bits (210), Expect = 2e-16
Identities = 56/194 (28%), Positives = 93/194 (47%), Gaps = 43/194 (22%)
Query: 482 EEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQEN 541
+E+ +FAK K +R++LG TQ VG L G +SQ+ ICR
Sbjct: 49 KELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICR----------------- 91
Query: 542 TIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFIG 601
FE L ++ K+ K++P+L++W+ EA+ +NL E
Sbjct: 92 -------------------FEALQLSFKNMCKLRPLLQKWVEEADNN-----ENLQEICK 127
Query: 602 SEP--SKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKR 659
+E ++++RTS + L F + P+ Q+++ IA++L +++VVRVWFCN+R
Sbjct: 128 AETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRR 187
Query: 660 QALKNTIKRLKQHE 673
Q K + Q E
Sbjct: 188 QKGKRSSSDYAQRE 201
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 85.1 bits (209), Expect = 2e-16
Identities = 103/342 (30%), Positives = 134/342 (39%), Gaps = 58/342 (16%)
Query: 161 IMTLPLQNLQATSSLNSQLQQL-QLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQP 219
++ L QN Q QLQ++ QLQLQQQQQQQQQQ Q QQQ
Sbjct: 220 LIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ----------------QQQQQQA 263
Query: 220 LQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQS 279
LQ PP Q PP Q P P+ L PQQ Q H+Q+ P QQ PP +Q
Sbjct: 264 LQAQPPIQQPPMQQPQPPPSQAL-----PQQLQQMHHTQHHQPPPQPQQ---PPVAQNQ- 314
Query: 280 PGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNA 339
PS L P + Q PL SQA A M F A +Q Q
Sbjct: 315 -----PSQLPPQSQTQ----PLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
Query: 340 QGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQ 399
Q + T P Q + Q P L + + GQ + T P + Q
Sbjct: 366 QQTAVQTAQAAQMVAPGVQVS--------QSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ 417
Query: 400 GITLSPIKPGQQLHQP-SQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSS 458
PGQ QP S S G A S + L Q SQSPV + + S S
Sbjct: 418 --------PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQP--SQSPVTARTPQNFSVPSPG 467
Query: 459 ALSVGQLVSNPQTAAGEVDGVN---LEEIREFAKAFK-IRRL 496
L+ S+ + AG L+++++ +K + +RR+
Sbjct: 468 PLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRM 509
Score = 59.7 bits (143), Expect = 9e-09
Identities = 77/250 (30%), Positives = 94/250 (37%), Gaps = 45/250 (18%)
Query: 79 QHQASQTHPPF-------PVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPFNMAGQL 131
Q QA Q PP P P QQL PP QP + N QL
Sbjct: 260 QQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ-NQPSQL 318
Query: 132 GGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQ 191
Q + Q LV+ A A LP Q L L + +Q Q
Sbjct: 319 PPQ------------SQTQPLVSQAQA-----LPGQMLYTQPPLKFVRAPMVVQQPPVQP 361
Query: 192 Q-QQQQPPPSTNQHPQ---PAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQ 247
Q QQQQ T Q Q P Q S P+P QQ PP P Q +PQ
Sbjct: 362 QVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP----QPSPQ 417
Query: 248 PQQ--HQPHSHSQNQNQPSPTQQSSSPPQKPSQSP-------GHGLPSP---LTPPNPLQ 295
P Q QP+S+ + PSP+ SP +PSQSP +PSP TP NP
Sbjct: 418 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 477
Query: 296 LVNNPLASQA 305
+++ +SQA
Sbjct: 478 VMSPAGSSQA 487
Score = 33.1 bits (74), Expect = 0.88
Identities = 42/190 (22%), Positives = 67/190 (35%), Gaps = 10/190 (5%)
Query: 69 PALSDPGTPDQHQASQTHPPFP-VGPQPLLTAQQLASAV-AGVMPGGPPALNQPILIPFN 126
P LS P Q Q Q+ PP P PQP + Q S V +G P L P P
Sbjct: 391 PMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ 450
Query: 127 MAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQL 186
Q + P T + + AG Q L L+ ++ L+ +
Sbjct: 451 SPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMI 510
Query: 187 QQQQQQQQQQPPPSTNQH-----PQPAPQAPSQSQQQ---PLQPTPPQQPPPASQQPPAP 238
+ + + ++ S + P+ + P ++ Q+ L+ P PP P
Sbjct: 511 NKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVP 570
Query: 239 TSQLQQAPQP 248
++ Q QP
Sbjct: 571 PTKQQYLCQP 580
>gi|227430410 POU class 5 homeobox 1B [Homo sapiens]
Length = 359
Score = 82.8 bits (203), Expect = 1e-15
Identities = 90/347 (25%), Positives = 144/347 (41%), Gaps = 68/347 (19%)
Query: 341 GQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQG 400
G + P PG G + V P+T + QG IG + P G
Sbjct: 3 GHLASDFAFSPPPGGGGDGPWGAEPGWVDPLT---WLSFQGPPGGPGIGPGVGPGSEVWG 59
Query: 401 ITLSPIKPGQQL-----HQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSS 455
I P P +L + Q VG G L SQ S++ V S+S+ +S
Sbjct: 60 IP--PCPPPYELCGGMAYCGPQVGVGLVPQGG----LETSQPE-SEAGVGVESNSNGASP 112
Query: 456 SSSALSVG-------QLVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQA 508
+ G +L NP+ + ++ + +E+ +FAK K +R++LG TQ VG
Sbjct: 113 EPCTVPPGAVKLEKEKLEQNPEKSQ-DIKALQ-KELEQFAKLLKQKRITLGYTQADVGLI 170
Query: 509 LSATEGPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITP 568
L G +SQ ICR FE L ++
Sbjct: 171 LGVLFGKVFSQKTICR------------------------------------FEALQLSF 194
Query: 569 KSAQKIKPVLERWMAEAEARHRAGMQNLTEFIGSEP--SKKRKRRTSFTPQALEILNAHF 626
K+ K++P+L++W+ EA+ +NL E +E ++++RTS + L F
Sbjct: 195 KNMCKLRPLLQKWVEEADNN-----ENLQEICKAETLMQARKRKRTSIENRVRGNLENLF 249
Query: 627 EKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNTIKRLKQHE 673
+ P+ Q ++ IA++L +++VVRVWFCN+RQ K + Q E
Sbjct: 250 LQCPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQRE 295
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 75.9 bits (185), Expect = 1e-13
Identities = 116/427 (27%), Positives = 157/427 (36%), Gaps = 84/427 (19%)
Query: 77 PDQHQA---SQTHPPFPVGPQPLLTAQQLASAVAGVMPG--GPPALNQPILIPFN----- 126
P HQ Q P P GPQ +L Q+A + PG GP ++ +L+ +
Sbjct: 3779 PSSHQGLLVQQLSPQPPQGPQGMLGPAQVA-VLQQQHPGALGPQGPHRQVLMTQSRVLSS 3837
Query: 127 --MAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAG------GIMT---LPLQNLQATSSL 175
+A Q G G L Q + AG +M+ P + Q SL
Sbjct: 3838 PQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSL 3897
Query: 176 NSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQP 235
QLQQ Q QLQQQQQ QQQQ Q Q Q QQQ LQ QQ QQ
Sbjct: 3898 Q-QLQQQQ-QLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQ- 3954
Query: 236 PAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQ 295
Q QQ Q QQ Q Q + ++ SP Q+ Q G P P PLQ
Sbjct: 3955 ----LQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALG---PGMPAKPLQ 4007
Query: 296 LVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGP 355
++P A G L L+T + + +P
Sbjct: 4008 HFSSP------------------GALGPTL---------LLTGKEQNTV-------DPAV 4033
Query: 356 SSQAASGTQGLQVQPI----TPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQ 411
SS+A G Q P+ TP+ + G++ ++ G+ L ++ Q +P
Sbjct: 4034 SSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQ----PQPQPSSL 4089
Query: 412 LHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSNPQT 471
QP GQ Q +LLH A + S SSS A SV L++ P
Sbjct: 4090 QLQPPLRLPGQQQQQVSLLHTAGG----------GSHGQLGSGSSSEASSVPHLLAQPSV 4139
Query: 472 AAGEVDG 478
+ G+ G
Sbjct: 4140 SLGDQPG 4146
Score = 57.0 bits (136), Expect = 6e-08
Identities = 71/268 (26%), Positives = 89/268 (33%), Gaps = 53/268 (19%)
Query: 167 QNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQ------APSQSQQQP- 219
Q Q QLQQ Q QLQQQQQQQQQQ Q +P Q QQQ
Sbjct: 3936 QQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV 3995
Query: 220 -LQPTPPQQPPPASQQP------------------PAPTSQLQQAPQPQQH-------QP 253
L P P +P P PA +S+ + P Q P
Sbjct: 3996 ALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTP 4055
Query: 254 HSHSQNQNQPSPTQQSSSP-----PQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAA 308
S + + P+ S PQ Q L PL P Q + L + +
Sbjct: 4056 ESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGS 4115
Query: 309 AAAMSSIASSQA------FGNALSSLQGVTGQLVTNAQG---------QIIGTIPLMPNP 353
+ S +SS+A SL G + N G T P P P
Sbjct: 4116 HGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKP 4175
Query: 354 GPSSQAASGTQGLQVQPITPQLLTNAQG 381
GP Q+ G G+ + P QL QG
Sbjct: 4176 GPVLQSGQGLPGVGIMPTVGQLRAQLQG 4203
Score = 53.9 bits (128), Expect = 5e-07
Identities = 95/358 (26%), Positives = 123/358 (34%), Gaps = 48/358 (13%)
Query: 175 LNSQLQQLQLQLQQQQQQQQQQPPPSTNQH-------PQPAPQAPSQSQQQPLQPTPPQQ 227
L Q QL +LQQQQQQQQQQ QH Q Q P Q L P P
Sbjct: 3723 LQQQRMQLAQKLQQQQQQQQQQ------QHLLGQVAIQQQQQQGPGVQTNQALGPKPQGL 3776
Query: 228 PPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSP 287
PP+S Q Q +PQP P Q P Q H P
Sbjct: 3777 MPPSSHQ---GLLVQQLSPQP--------------PQGPQGMLGPAQVAVLQQQH--PGA 3817
Query: 288 LTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTI 347
L P P + V L +Q+ ++ + G+ L + Q Q QG + G
Sbjct: 3818 LGPQGPHRQV---LMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLS 3874
Query: 348 PLMPNPGPSSQAASGTQGLQVQPI--TPQLLTNAQGQIIATVIGNQILPVINTQGITLSP 405
L S + SG L QP+ QL Q Q + Q + Q +
Sbjct: 3875 HLQ----QSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQ 3930
Query: 406 IKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQL 465
++ QQ Q Q Q Q L Q Q +Q + S L Q
Sbjct: 3931 LQQQQQQQQLQQQQQQQLQQQQQQLQ-QQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQ 3989
Query: 466 VSNPQTAAGEVDGVNLEEIREFAK--AFKIRRLSLGLTQTQVGQALS--ATEGPAYSQ 519
Q A G G+ + ++ F+ A L G Q V A+S ATEGP+ Q
Sbjct: 3990 QQQQQVALG--PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQ 4045
Score = 50.4 bits (119), Expect = 5e-06
Identities = 63/234 (26%), Positives = 84/234 (35%), Gaps = 31/234 (13%)
Query: 91 VGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQ-------QGLVLTLP- 142
+G P ++ A + GGPPA +L P ++G G + LTLP
Sbjct: 3168 MGTGPFSSSGHTAEKASFGATGGPPA---HLLTPSPLSGPGGSSLLEKFELESGALTLPG 3224
Query: 143 --TANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPS 200
A+ + + ++ A + L L+ + QQL QLQ QQQQQQQ S
Sbjct: 3225 GPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHS 3284
Query: 201 TNQHPQPA-----------PQAPSQSQQQPLQPTPPQQP----PPASQQPPAPTSQLQQA 245
P PA P QQ L +QP P QPPA Q + A
Sbjct: 3285 LLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLA 3344
Query: 246 PQPQQHQPHSH---SQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQL 296
P H Q+ Q Q SS P + G PS P L +
Sbjct: 3345 PSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAM 3398
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 3/111 (2%)
Query: 184 LQLQQQQQQQQQQPPPSTNQHPQPAPQAP-SQSQQQPLQPTPPQQPPPASQQPPAPTSQL 242
L L + ++ PPP + P +P S ++ PL P P PA + P +P +
Sbjct: 483 LHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA 542
Query: 243 QQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLP--SPLTPP 291
P + P S + SP ++S P +SP P SP++PP
Sbjct: 543 SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPP 593
Score = 48.1 bits (113), Expect = 3e-05
Identities = 70/347 (20%), Positives = 122/347 (35%), Gaps = 55/347 (15%)
Query: 5 LQDPMIAGQVSKPLLSVRSEMNAELRGEDKAATSDSELNE-PLLAPVES---NDSEDTPS 60
+Q M+ G L + A R ++A SE+ LLA + + N +ED
Sbjct: 4634 VQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRM 4693
Query: 61 KLFGARGNPALSDPGTPDQHQASQTHPPFP-------------VGPQPLLTAQQLASAVA 107
+ +P P + + + P FP + P L +
Sbjct: 4694 ESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFP 4753
Query: 108 GVMPGGPPALNQPILIPFNMAGQ-LGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPL 166
P G L P +P + G + ++LT+ A N+ G++ A A
Sbjct: 4754 DTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVA--------- 4804
Query: 167 QNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQ 226
+ L +++ + + P P+ +++ L+ P
Sbjct: 4805 -------------ELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPD 4851
Query: 227 QPPPASQQPPAPT------SQL-------QQAPQPQQHQPHSHSQNQNQPSPTQQSSSPP 273
P +Q A SQL Q++P P+ HS++ N + Q S+ PP
Sbjct: 4852 TGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPP 4911
Query: 274 QKPSQSPGHGLPSPLTPPNP--LQLVNNPLASQAAAAAAAMSSIASS 318
++PS P PSP +PP ++L PLA + ++S S
Sbjct: 4912 EEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPES 4958
Score = 47.8 bits (112), Expect = 3e-05
Identities = 73/286 (25%), Positives = 105/286 (36%), Gaps = 39/286 (13%)
Query: 10 IAGQVSKPLLS-VRSEMNAELRGEDKAATSDSELNEPLLAP--VESNDSEDTPSKLFGAR 66
++ Q +P LS V E + E+ + SE EP L+P ES+ S + R
Sbjct: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE--EPCLSPRPEESHLSPELEKPPLSPR 863
Query: 67 GNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPFN 126
+PG Q A + P FP +P L+ L A PG PP P +P +
Sbjct: 864 PEKPPEEPG---QCPAPEELPLFPPPGEPSLSP--LLGEPALSEPGEPPLSPLPEELPLS 918
Query: 127 MAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQL 186
+G+ L+ P + ++ AAA + S L +L+
Sbjct: 919 PSGEPSLSPQLMPPDPLP--PPLSPIITAAAPPAL---------------SPLGELEYPF 961
Query: 187 QQQQQQQQQQP--PPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQ 244
+ + P P P P+A + P PP PP+ P P S +
Sbjct: 962 GAKGDSDPESPLAAPILETPISPPPEANCTDPE----PVPPMILPPSPGSPVGPASPILM 1017
Query: 245 APQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTP 290
P P Q P Q SP Q SPP P +PSPL+P
Sbjct: 1018 EPLPPQCSPLLQHSLVPQNSPPSQ-CSPPALPL-----SVPSPLSP 1057
Score = 45.8 bits (107), Expect = 1e-04
Identities = 60/278 (21%), Positives = 103/278 (37%), Gaps = 20/278 (7%)
Query: 33 DKAATSDSELNEPLLAPVESNDSEDTPSKLFGARGNPALSDPGTPDQHQASQTHPP---- 88
+++ TS L P E + P L +R P P +P ++ + PP
Sbjct: 454 EESPTSPPPEASRLSPPPEELPASPLPEALHLSR--PLEESPLSPPPEESPLSPPPESSP 511
Query: 89 -FPVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQQGLVLTLPTANLT 147
P+ PL ++ + A P PP P+ PF + + LPT+
Sbjct: 512 FSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPE----ELPTSPPP 567
Query: 148 NIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQL--QLQLQQQQQQQQQQPPPSTNQHP 205
L + P ++ + S+L + L ++ PPP ++
Sbjct: 568 EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLS 627
Query: 206 QPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSP 265
P +P P + +P PP S+ P P + + P + P S ++ SP
Sbjct: 628 PPPEDSP---MSPPPEESPMSPPPEVSRLSPLPV--VSRLSPPPEESPLSPPPEESPTSP 682
Query: 266 TQQSS--SPPQKPSQSPGHGLPSPLTPPNPLQLVNNPL 301
++S SPP + S + SP +PP L++ PL
Sbjct: 683 PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720
Score = 45.4 bits (106), Expect = 2e-04
Identities = 73/291 (25%), Positives = 103/291 (35%), Gaps = 67/291 (23%)
Query: 56 EDTPSKLFGARGNPAL--SDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGG 113
++T + GA G P ++P +P Q S+ PF Q S++ G+ P
Sbjct: 2704 KETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPF--------AGTQDKSSLVGLPPS- 2754
Query: 114 PPALNQPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATS 173
L+ PIL P + + P++ N + LV + QA
Sbjct: 2755 --KLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS-------------QAFY 2799
Query: 174 SLNSQLQQLQLQLQQQQQQQQQQPPPSTNQH--------PQPAPQAPSQSQQQPLQPTPP 225
L LQ QQQQ QQQQ +T+ P P+ Q+ PL
Sbjct: 2800 QRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGIST 2859
Query: 226 QQPPPASQQP-PAPTSQL--------------------QQAPQPQQHQPHSHSQNQNQPS 264
+ P P P PA +Q Q PQ + P S ++ P
Sbjct: 2860 RLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPE 2919
Query: 265 PTQ---QSSSPPQKPSQSPGHGLPSPLTP---------PNPLQLVNNPLAS 303
+ S PPQKPS P L + L P P L+LVN P +S
Sbjct: 2920 GLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSS 2970
Score = 44.7 bits (104), Expect = 3e-04
Identities = 109/487 (22%), Positives = 165/487 (33%), Gaps = 64/487 (13%)
Query: 173 SSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQ--SQQQPLQPTPPQQPPP 230
++L ++ + Q Q QQQQQQQQQQ P +P+ ++ Q P P Q PP
Sbjct: 3589 TNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPP 3648
Query: 231 ASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHG-LPSPLT 289
Q A +L QP N QQ S P G P L
Sbjct: 3649 GGQ---AGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLA 3705
Query: 290 ----PPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIG 345
P+ L L Q A Q Q + GQ+ Q Q
Sbjct: 3706 LRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQ----QQQQQQHLLGQVAIQQQQQQGP 3761
Query: 346 TIPLMPNPGPSSQA---ASGTQGLQVQPITPQLLTNAQGQI---IATVIGNQILPVINTQ 399
+ GP Q S QGL VQ ++PQ QG + V+ Q + Q
Sbjct: 3762 GVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQ 3821
Query: 400 G------ITLSPIKPGQQLHQPSQTSVG-------------QAASQGNLLHLAHSQASMS 440
G +T S + QL Q Q +G Q QG++ L+H Q S+
Sbjct: 3822 GPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLM 3881
Query: 441 QSPVRQASSSSSSSSSSSALSVGQLVSNPQ---------TAAGEVDGVNLEEIREFAKAF 491
+ S+ S QL Q ++ L++ ++ +
Sbjct: 3882 SHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQ 3941
Query: 492 KIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFL--PQEAQENTIA--SSL 547
+ ++ L Q Q+ Q + Q + +L L PQ+ Q+ +A +
Sbjct: 3942 QQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM 4001
Query: 548 TAK-----LNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAG---MQNLTEF 599
AK +PG L P L +T K + P + E + H+ G + E
Sbjct: 4002 PAKPLQHFSSPGALGPT----LLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPES 4057
Query: 600 IGSEPSK 606
+ +EP +
Sbjct: 4058 MATEPGE 4064
Score = 42.4 bits (98), Expect = 0.001
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 34/151 (22%)
Query: 170 QATSSLNSQLQQL----QLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQS---------- 215
Q + LN ++ L + L ++ PPP ++ P + P+
Sbjct: 429 QLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRP 488
Query: 216 -QQQPLQPTP---PQQPPPASQQPPAPTSQLQQAP--QPQQHQPHSHSQNQNQPSPTQQS 269
++ PL P P P PPP S +P S L+++P P++ P + P P
Sbjct: 489 LEESPLSPPPEESPLSPPPES----SPFSPLEESPLSPPEESPPSPALETPLSPPPEASP 544
Query: 270 SSPPQKPSQSPGHGLPSPLTPPNPLQLVNNP 300
SPP + SPL+PP P +L +P
Sbjct: 545 LSPPFE---------ESPLSPP-PEELPTSP 565
Score = 41.2 bits (95), Expect = 0.003
Identities = 67/295 (22%), Positives = 106/295 (35%), Gaps = 44/295 (14%)
Query: 45 PLLAPVESNDSEDTPSKLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLAS 104
PL P E + + P +R +P D T + S PP P+ L + L
Sbjct: 670 PLSPPPEESPTSPPPE---ASRLSPPPEDSPTSPPPEDSPASPP----PEDSLMSLPLEE 722
Query: 105 AVAGVMPGGP---PALNQPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGI 161
+ +P P P P L P L + P A ++ +
Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782
Query: 162 MTLPLQNLQATSS-LNSQLQQLQLQLQQQQQQQQQQPP-PSTNQHPQPAPQAPSQSQQQP 219
P + QA L+ Q ++L L Q ++ P P + P+ + +P QS++
Sbjct: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP-QSEEPC 841
Query: 220 LQPTPPQ-------QPPPASQQPPAPTSQLQQAPQPQQ----------------HQPHSH 256
L P P + + PP S +P P + Q P P++ +P
Sbjct: 842 LSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALS 901
Query: 257 SQNQN--QPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAA 309
+ P P + SP +PS SP L PP+PL +P+ + AA A
Sbjct: 902 EPGEPPLSPLPEELPLSPSGEPSLSP------QLMPPDPLPPPLSPIITAAAPPA 950
Score = 40.8 bits (94), Expect = 0.004
Identities = 35/132 (26%), Positives = 57/132 (43%), Gaps = 16/132 (12%)
Query: 192 QQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQP--PPASQQPPAP---TSQLQQAP 246
Q + +P +P +AP +++ PL P P + P PP + P +P S+L P
Sbjct: 413 QCEAKPLGKAGVQLEPQLEAPL-NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPP 471
Query: 247 QPQQHQPHSHSQNQNQPSPTQQSSSPPQK------PSQSPGHGL-PSPLTPPN---PLQL 296
+ P + + ++P S PP++ P SP L SPL+PP P
Sbjct: 472 EELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPA 531
Query: 297 VNNPLASQAAAA 308
+ PL+ A+
Sbjct: 532 LETPLSPPPEAS 543
Score = 40.4 bits (93), Expect = 0.006
Identities = 34/137 (24%), Positives = 52/137 (37%), Gaps = 15/137 (10%)
Query: 197 PPPSTNQHPQ-------PAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTS----QLQQA 245
PPPS+ Q P+ P+ Q P+++Q P P P+ P + PP S QL
Sbjct: 4309 PPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADT 4368
Query: 246 PQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQA 305
+ P N + +QSS P Q G +P + L + P
Sbjct: 4369 LFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPE----ASQLSIKQEPREEPC 4424
Query: 306 AAAAAAMSSIASSQAFG 322
A A ++ A+ + G
Sbjct: 4425 ALGAQSVKREANGEPIG 4441
Score = 39.3 bits (90), Expect = 0.012
Identities = 35/121 (28%), Positives = 48/121 (39%), Gaps = 21/121 (17%)
Query: 208 APQAPSQSQQQPLQP---TPPQQPPPASQQPPAPTSQLQQAPQPQQH----QPHSHSQNQ 260
AP P SQ +P P PQ+PPPA AP P H +P S++
Sbjct: 2329 APLTPRASQVEPQSPGLGLRPQEPPPAQAL----------APSPPSHPDIFRPGSYTDPY 2378
Query: 261 NQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQA 320
QP T + PQ P LP P +P V SQ+++ + S++A
Sbjct: 2379 AQPPLTPR----PQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEA 2434
Query: 321 F 321
F
Sbjct: 2435 F 2435
Score = 38.9 bits (89), Expect = 0.016
Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 20/123 (16%)
Query: 181 QLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQ----PPPASQQPP 236
QL+ QL+ ++ PP P+ +P +P ++ P P P PP P
Sbjct: 425 QLEPQLEAPLNEEMPLLPP-----PEESPLSPPP-EESPTSPPPEASRLSPPPEELPASP 478
Query: 237 AP-----TSQLQQAP--QPQQHQPHSHSQNQNQPSPTQQSS-SPPQKPSQSPGHGLPSPL 288
P + L+++P P + P S + SP ++S SPP++ SP L +PL
Sbjct: 479 LPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSP--ALETPL 536
Query: 289 TPP 291
+PP
Sbjct: 537 SPP 539
Score = 38.9 bits (89), Expect = 0.016
Identities = 121/516 (23%), Positives = 178/516 (34%), Gaps = 84/516 (16%)
Query: 45 PLLAPVESNDSEDTPSKLFGARGNPALSDPG----TPDQHQASQTHPPFPVGPQPLLTAQ 100
P P S + GA P PG TP Q P P +
Sbjct: 2194 PTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLD 2253
Query: 101 QLASAVAGVMPGGP---PALNQPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAA 157
LA + + GG P L+ P A ++ ++ L + P+ N+ G V + +
Sbjct: 2254 NLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEE-LGASSPSYGPPNL-GFVDSPS 2311
Query: 158 AGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQ---QQQQPPPSTNQHPQPAPQAPSQ 214
+G L L+ + L Q++ Q + Q+PPP+ P P P P
Sbjct: 2312 SG--THLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSP-PSHPDI 2368
Query: 215 SQQQPLQPTPPQQPPPAS--QQPPAPTSQLQQAPQ----------PQQHQPHSHSQNQNQ 262
+ P T P PP + QPP P S P+ P Q S SQ+
Sbjct: 2369 FR--PGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLT 2426
Query: 263 PSPTQQSS---SP--PQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIA- 316
P P + SP P+ S P PS +P ++ P Q A S+A
Sbjct: 2427 PRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAH 2486
Query: 317 -SSQAFGNALSSLQGVTGQL---VTNAQ----------GQIIGTIPLMPNPGPSSQAASG 362
S A G + G G+L V + Q G +GT M P +
Sbjct: 2487 TSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPS 2546
Query: 363 TQGLQVQPITP------------QLLTNAQGQIIATVIGN---QILPVINTQGIT----- 402
+ QP P L Q GN P+ + G T
Sbjct: 2547 LKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYG 2606
Query: 403 LSPIKPGQQLHQPSQTSVGQAASQGNLLHLAH--SQASMSQSPVRQASSSSSSSSSSSAL 460
LSP++P L P A G+L +L+H SQ S SPV + + SS L
Sbjct: 2607 LSPLRPPSVLPPP--------APDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSS--L 2656
Query: 461 SVGQLVSNPQTAAGEVDGVNLEEIREFAKAFKIRRL 496
+ +L P T + G++ E+ + + ++R L
Sbjct: 2657 ATAEL---PGTQDPGMSGLSQTELEKQRQRQRLREL 2689
Score = 38.1 bits (87), Expect = 0.027
Identities = 42/191 (21%), Positives = 72/191 (37%), Gaps = 10/191 (5%)
Query: 191 QQQQQQPPPSTNQHPQPAPQAPSQS--QQQPLQPTPPQQ---PPP--ASQQPPAPTSQLQ 243
++ PPP ++ P ++P ++ PL P P PPP + PP S +
Sbjct: 586 EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS 645
Query: 244 QAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLAS 303
P+ + P + P S PP++ SP S L+PP P +P
Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPE-ASRLSPP-PEDSPTSPPPE 703
Query: 304 QAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGT 363
+ A+ S+ S + L L QL ++G + P P+ P + +
Sbjct: 704 DSPASPPPEDSLMSLPLEESPLLPLP-EEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS 762
Query: 364 QGLQVQPITPQ 374
+ ++PQ
Sbjct: 763 PQAEEPHLSPQ 773
Score = 36.6 bits (83), Expect = 0.080
Identities = 35/119 (29%), Positives = 47/119 (39%), Gaps = 15/119 (12%)
Query: 185 QLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPT-PPQQPPPASQQP-------P 236
+L ++ PPP + P P+A S PT PP + PAS P P
Sbjct: 661 RLSPPPEESPLSPPPEESP-TSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLP 719
Query: 237 APTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSP-PQKPSQSP----GHGLPSPLTP 290
S L P+ Q P S + + P P + SP P++P SP H P P P
Sbjct: 720 LEESPLLPLPEEPQLCPRSEGPHLS-PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEP 777
Score = 35.4 bits (80), Expect = 0.18
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 4/102 (3%)
Query: 194 QQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQP 253
Q QP QP P Q + +PL Q P Q AP ++ P + P
Sbjct: 393 QGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEP----QLEAPLNEEMPLLPPPEESP 448
Query: 254 HSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQ 295
S ++ SP ++S P + P LP L PL+
Sbjct: 449 LSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLE 490
Score = 33.9 bits (76), Expect = 0.52
Identities = 48/205 (23%), Positives = 73/205 (35%), Gaps = 26/205 (12%)
Query: 182 LQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTP---PQQPPP--ASQQPP 236
L+L Q Q Q P +P P+ P+ P P+P P QPP AS +P
Sbjct: 2161 LKLPPQVPAQVPSQDPFGLAPAYPLE-PRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPG 2219
Query: 237 A--PTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPP--- 291
A P P +HQP + P+ + + P+ P G L+PP
Sbjct: 2220 AGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFG 2279
Query: 292 ---NPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIP 348
L++ L + + + S + G L L+ T + P
Sbjct: 2280 ESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPD---------VFKAP 2330
Query: 349 LMPNPGPSSQAASGTQGLQVQPITP 373
L P +SQ + GL ++P P
Sbjct: 2331 LTPR---ASQVEPQSPGLGLRPQEP 2352
Score = 33.5 bits (75), Expect = 0.68
Identities = 18/65 (27%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 191 QQQQQQPPPSTNQHPQPAPQAPSQSQQQPL--QPTPPQQPPPASQQPPAPTSQLQQAPQP 248
+Q PP + P P +P+ +PL PT P PP P +S P+P
Sbjct: 4904 RQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
Query: 249 QQHQP 253
+ P
Sbjct: 4964 RARPP 4968
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 74.7 bits (182), Expect = 3e-13
Identities = 122/464 (26%), Positives = 159/464 (34%), Gaps = 86/464 (18%)
Query: 57 DTPSKLFGARGNPALSDPGTPDQHQASQTHPPFPV----GPQPLLTAQQLASAV------ 106
D S+ +GA A + + Q S P P G QPL Q +S +
Sbjct: 331 DMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKM 390
Query: 107 -----AGVMP----GGPPALNQPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAA 157
G P GPP+ Q GQ G Q P +QG +A
Sbjct: 391 RPQPYGGTNPYSQQQGPPSGPQQ---GHGYPGQPYGSQ-----TPQRYPMTMQGRAQSAM 442
Query: 158 AGGIMT--LPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQP----PPSTNQHPQPAPQA 211
G T +P Q S Q Q Q QQQQ P PPS H QP+ Q
Sbjct: 443 GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502
Query: 212 PSQSQ----------------QQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHS 255
QSQ Q P Q +P P S P SQ + QPQ P+
Sbjct: 503 QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYS-QPQAQSPYQ 561
Query: 256 HSQ-NQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSS 314
Q Q PS Q ++ PQ SQ S P P +L + SQA++A + SS
Sbjct: 562 QQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSS 621
Query: 315 IASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQ 374
+ +L S L + +GT + +PG S+ S +QG Q P
Sbjct: 622 KGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGAL-SPGVSTSGISSSQGEQSNPAQSP 680
Query: 375 LLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSVGQAAS--QGNLLHL 432
+ SP PG + PS + VG AS Q L
Sbjct: 681 FSPHT------------------------SPHLPG--IRGPSPSPVGSPASVAQSRSGPL 714
Query: 433 AHSQASMSQSPVRQASSSSSS------SSSSSALSVGQLVSNPQ 470
+ + +Q P R S S S + SS A G + NPQ
Sbjct: 715 SPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ 758
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/159 (26%), Positives = 63/159 (39%), Gaps = 32/159 (20%)
Query: 170 QATSSLNSQLQQLQLQLQQQQQQQQQQP------PPSTNQHPQPAPQAPSQSQQQP-LQP 222
Q T S S Q + QQQQQ ++P PP+ + S Q QP Q
Sbjct: 1346 QGTPS-GSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQ 1404
Query: 223 TPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGH 282
PP QP PASQQ A Q +PQ + + ++ P +++ ++P+ P +
Sbjct: 1405 LPPAQPQPASQQQAA-----QPSPQQDVYNQYGNAY------PATATAATERRPAGGPQN 1453
Query: 283 GLPSPL------TPPN-------PLQLVNNPLASQAAAA 308
P PP P Q++ P+ + A A
Sbjct: 1454 QFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVA 1492
Score = 40.4 bits (93), Expect = 0.006
Identities = 41/141 (29%), Positives = 54/141 (38%), Gaps = 21/141 (14%)
Query: 165 PLQNLQATSSLNSQLQQLQLQLQQQQQQQQQ----------QPPPSTNQHPQPAPQAPSQ 214
P NL ++ + + QQQQQQQQ+ Q PS + P Q
Sbjct: 1305 PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQ 1364
Query: 215 SQQQPLQPTPPQQPPPASQQP----PAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSS 270
QQ +P PPA + P S Q PQ QQ P Q QP+ QQ++
Sbjct: 1365 QQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPP-----AQPQPASQQQAA 1419
Query: 271 --SPPQKPSQSPGHGLPSPLT 289
SP Q G+ P+ T
Sbjct: 1420 QPSPQQDVYNQYGNAYPATAT 1440
Score = 37.0 bits (84), Expect = 0.061
Identities = 28/99 (28%), Positives = 37/99 (37%), Gaps = 8/99 (8%)
Query: 201 TNQHPQPAPQAPSQSQQQP----LQPTPPQQPPPAS--QQPPAPTSQLQQAPQPQQHQPH 254
T+Q PS +QP P PP PP S Q PP+ + + Q P
Sbjct: 1535 TDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRP 1594
Query: 255 SHSQNQNQPSPTQQSSSPPQK--PSQSPGHGLPSPLTPP 291
++ SP S QK P H P+P+ PP
Sbjct: 1595 MENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPP 1633
Score = 32.3 bits (72), Expect = 1.5
Identities = 35/132 (26%), Positives = 47/132 (35%), Gaps = 14/132 (10%)
Query: 205 PQP--APQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQ------APQPQQHQPHSH 256
PQP P P P + PPQQ Q+ + +Q +P P Q
Sbjct: 1305 PQPNLMPSNPDSGMYSPSR-YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQ 1363
Query: 257 SQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPL----ASQAAAAAAAM 312
Q QN P + PP K + + +P P Q P ASQ AA +
Sbjct: 1364 QQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSP 1423
Query: 313 SSIASSQAFGNA 324
+Q +GNA
Sbjct: 1424 QQDVYNQ-YGNA 1434
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 74.7 bits (182), Expect = 3e-13
Identities = 122/464 (26%), Positives = 159/464 (34%), Gaps = 86/464 (18%)
Query: 57 DTPSKLFGARGNPALSDPGTPDQHQASQTHPPFPV----GPQPLLTAQQLASAV------ 106
D S+ +GA A + + Q S P P G QPL Q +S +
Sbjct: 331 DMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKM 390
Query: 107 -----AGVMP----GGPPALNQPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAA 157
G P GPP+ Q GQ G Q P +QG +A
Sbjct: 391 RPQPYGGTNPYSQQQGPPSGPQQ---GHGYPGQPYGSQ-----TPQRYPMTMQGRAQSAM 442
Query: 158 AGGIMT--LPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQP----PPSTNQHPQPAPQA 211
G T +P Q S Q Q Q QQQQ P PPS H QP+ Q
Sbjct: 443 GGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQ 502
Query: 212 PSQSQ----------------QQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHS 255
QSQ Q P Q +P P S P SQ + QPQ P+
Sbjct: 503 QPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYS-QPQAQSPYQ 561
Query: 256 HSQ-NQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSS 314
Q Q PS Q ++ PQ SQ S P P +L + SQA++A + SS
Sbjct: 562 QQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSS 621
Query: 315 IASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQ 374
+ +L S L + +GT + +PG S+ S +QG Q P
Sbjct: 622 KGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGAL-SPGVSTSGISSSQGEQSNPAQSP 680
Query: 375 LLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSVGQAAS--QGNLLHL 432
+ SP PG + PS + VG AS Q L
Sbjct: 681 FSPHT------------------------SPHLPG--IRGPSPSPVGSPASVAQSRSGPL 714
Query: 433 AHSQASMSQSPVRQASSSSSS------SSSSSALSVGQLVSNPQ 470
+ + +Q P R S S S + SS A G + NPQ
Sbjct: 715 SPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ 758
Score = 33.9 bits (76), Expect = 0.52
Identities = 35/131 (26%), Positives = 46/131 (35%), Gaps = 23/131 (17%)
Query: 165 PLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTP 224
P NL ++ + + QQQQQQQQ+ S Q Q TP
Sbjct: 1305 PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRH---------------DSYGNQFSTQGTP 1349
Query: 225 PQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQP--SPTQQSSSPPQK--PSQSP 280
P P+ Q Q +P P +N+ P SP S QK P
Sbjct: 1350 SGSPFPSQQTTMYQQQQQVSSPAPLPRP----MENRTSPSKSPFLHSGMKMQKAGPPVPA 1405
Query: 281 GHGLPSPLTPP 291
H P+P+ PP
Sbjct: 1406 SHIAPAPVQPP 1416
Score = 32.0 bits (71), Expect = 2.0
Identities = 27/106 (25%), Positives = 40/106 (37%), Gaps = 5/106 (4%)
Query: 214 QSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPP 273
Q P P P S+ PP Q QQ +Q + P P+QQ++
Sbjct: 1306 QPNLMPSNPDSGMYSP--SRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQ 1363
Query: 274 QKPSQSPGHGLPSPL---TPPNPLQLVNNPLASQAAAAAAAMSSIA 316
Q+ S LP P+ T P+ +++ + Q A S IA
Sbjct: 1364 QQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIA 1409
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 74.3 bits (181), Expect = 3e-13
Identities = 48/128 (37%), Positives = 57/128 (44%), Gaps = 10/128 (7%)
Query: 179 LQQLQLQLQQQQQQQQQQPPPST------NQHPQPAPQAPSQSQQQPLQPTPPQQPPPAS 232
L +Q+QL QQ Q+ Q P P +Q P P P P S QQ LQ PP PPP
Sbjct: 923 LTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPP-- 980
Query: 233 QQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPN 292
Q P P Q Q P+P QP S + QP P Q P P Q P P P P
Sbjct: 981 QPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP--PQPAKPQQ 1038
Query: 293 PLQLVNNP 300
+Q ++P
Sbjct: 1039 VIQHHHSP 1046
Score = 70.1 bits (170), Expect = 7e-12
Identities = 58/158 (36%), Positives = 69/158 (43%), Gaps = 43/158 (27%)
Query: 181 QLQLQLQQQQQQQ-----------QQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQ-QP 228
Q+QL LQQ Q+ Q Q QPPP P P P Q QQQP P PPQ QP
Sbjct: 927 QMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLP--PPPHPSVQQQLQQQPPPPPPPQPQP 984
Query: 229 PPASQQPPAP----------TSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQ 278
PP Q P P ++ +QQ P PQ QP H QP P Q P KP Q
Sbjct: 985 PPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQP-PHPPPGQQPPPPQ-----PAKPQQ 1038
Query: 279 ------SPGHGLPSPLT------PPNPLQLVNNPLASQ 304
SP H P + P+PL ++++P SQ
Sbjct: 1039 VIQHHHSPRHHKSDPYSTGHLREAPSPL-MIHSPQMSQ 1075
Score = 63.9 bits (154), Expect = 5e-10
Identities = 54/173 (31%), Positives = 66/173 (38%), Gaps = 25/173 (14%)
Query: 162 MTLPLQNLQATSSLNSQLQQLQLQLQQQ-----------QQQQQQQPPPSTNQHPQPAPQ 210
M L LQ LQ L +++Q Q QQQ QQQPPP PQP PQ
Sbjct: 928 MQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQ 987
Query: 211 APSQSQQQPLQPTP-------PQQPPPASQQPPAPTSQLQQAP----QPQQHQPHSHSQN 259
Q +P+ P Q PPP QQPP P Q P +PQQ H HS
Sbjct: 988 QQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPR 1047
Query: 260 QNQPSPTQQS---SSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAA 309
++ P +P SP LT +P Q P + AA+
Sbjct: 1048 HHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAAS 1100
Score = 58.9 bits (141), Expect = 2e-08
Identities = 67/243 (27%), Positives = 88/243 (36%), Gaps = 64/243 (26%)
Query: 185 QLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTP----PQQPPPASQQPPAPTS 240
Q+QQ QQPPP Q P P P Q QQQP P P PQQ PA + P P
Sbjct: 745 QMQQAPAPVPQQPPPPPQQ---PPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801
Query: 241 QLQ---------------------------------QAPQPQQHQ-------------PH 254
Q PQP +H P
Sbjct: 802 ATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPA 861
Query: 255 SHSQNQNQPS-PTQQSSSPPQKPSQSPGHG---LPSPLTPPNPLQLVNNPLASQAAAAAA 310
H+ QPS P+ ++++ P KP++ P +PL P P+ L A
Sbjct: 862 LHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAP 921
Query: 311 AMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQP 370
++S+ Q + L +Q T L+ + + Q PL P P PS Q Q LQ QP
Sbjct: 922 PLTSM-QMQLYLQQLQKVQPPT-PLLPSVKVQSQPPPPLPPPPHPSVQ-----QQLQQQP 974
Query: 371 ITP 373
P
Sbjct: 975 PPP 977
Score = 51.6 bits (122), Expect = 2e-06
Identities = 84/351 (23%), Positives = 114/351 (32%), Gaps = 85/351 (24%)
Query: 26 NAELRGEDKAATSDSELNEPLLAPVESNDS-----------------EDTPSKLFGARGN 68
++E ++++SDSE +E +AP + P+ +
Sbjct: 700 SSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPP 759
Query: 69 PALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPP---ALNQPIL--- 122
P P P Q Q PP P P QQ A A M PP A P+L
Sbjct: 760 PPQQPPPPPPPQQQQQPPPP----PPPPSMPQQAAPA----MKSSPPPFIATQVPVLEPQ 811
Query: 123 IPFNMAGQLGGQQGLVLTLPTANLT---------------NIQGLVAAAAAGGIM----T 163
+P ++ +G +L LP L N +V+ A + +
Sbjct: 812 LPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPS 871
Query: 164 LPLQNLQATSSLNSQLQQLQLQLQQQ----QQQQQQQPPPSTNQHPQPAPQAPSQSQQQP 219
P A ++ + L Q Q Q P PAP S Q
Sbjct: 872 RPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLY 931
Query: 220 LQ-------PTP-------PQQPPPASQQPPAPTSQ---LQQAPQPQQHQPHSHSQNQNQ 262
LQ PTP QPPP PP P+ Q QQ P P QP Q Q+Q
Sbjct: 932 LQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQ 991
Query: 263 PSP-----------TQQSSSPP---QKPSQSPGHGLPSPLTPPNPLQLVNN 299
P P T PP Q+P P P P P P Q++ +
Sbjct: 992 PPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQH 1042
Score = 42.4 bits (98), Expect = 0.001
Identities = 38/119 (31%), Positives = 43/119 (36%), Gaps = 25/119 (21%)
Query: 188 QQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQP-------PPASQQPPAPTS 240
Q Q Q PP HP PA P Q P+ P QP PP Q PPAP
Sbjct: 207 QTQTPQPNPPPVQATPHPFPA-VTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP-- 263
Query: 241 QLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQS------PGHGLPSPLTPPNP 293
APQP Q P + P P + +K + P H PS PP P
Sbjct: 264 ----APQPVQSHPPIIAAT---PQPVKTKKGVKRKADTTTPTTIDPIHEPPS--LPPEP 313
Score = 38.9 bits (89), Expect = 0.016
Identities = 44/198 (22%), Positives = 68/198 (34%), Gaps = 16/198 (8%)
Query: 232 SQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSP-------GHGL 284
S+ AP S+ + P +Q + H H Q Q +P PP P Q P
Sbjct: 717 SETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQP 776
Query: 285 PSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQII 344
P P PP+ Q + S A + Q G+ + T ++ Q ++
Sbjct: 777 PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPEL- 835
Query: 345 GTIPLMPNPGPSSQAASGTQGLQVQP-----ITPQLLTNAQGQIIATVIGNQILPVINTQ 399
P +P P S Q V P PQ + + A + P +
Sbjct: 836 --PPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNR-AAALPPKPARPPAVSP 892
Query: 400 GITLSPIKPGQQLHQPSQ 417
+T +P+ P + QP Q
Sbjct: 893 ALTQTPLLPQPPMAQPPQ 910
Score = 33.9 bits (76), Expect = 0.52
Identities = 57/253 (22%), Positives = 83/253 (32%), Gaps = 13/253 (5%)
Query: 59 PSKLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALN 118
PS ++ P L P P Q Q PP P PQP QQ + P +
Sbjct: 946 PSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFS 1005
Query: 119 QPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQ 178
I P GQ P Q ++ + + S
Sbjct: 1006 THIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSP 1065
Query: 179 LQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPL---------QPTPPQQPP 229
L Q+ Q Q Q PP Q + +A S Q QPL P +P
Sbjct: 1066 LMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPF 1125
Query: 230 PASQQPPAPT-SQLQQAPQPQQHQPHSHSQNQNQP--SPTQQSSSPPQKPSQSPGHGLP- 285
S +P P + +AP +P + +P P +Q++ PP P + P
Sbjct: 1126 SPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPK 1185
Query: 286 SPLTPPNPLQLVN 298
+P+ P L++ N
Sbjct: 1186 TPVAPKKDLKIKN 1198
Score = 32.3 bits (72), Expect = 1.5
Identities = 35/162 (21%), Positives = 58/162 (35%), Gaps = 24/162 (14%)
Query: 158 AGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQ 217
A + L LQ + + +++ +Q + + + +++ P + P +Q+
Sbjct: 150 AEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNT-----TQAST 204
Query: 218 QPLQPTPPQQPPPASQQP---PAPTSQL--------QQAPQPQQHQPHSHSQNQNQPSPT 266
P TP PPP P PA T L PQP Q P Q Q P+P
Sbjct: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
Query: 267 QQS--------SSPPQKPSQSPGHGLPSPLTPPNPLQLVNNP 300
Q ++ PQ G + T P + ++ P
Sbjct: 265 PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEP 306
>gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens]
Length = 858
Score = 73.9 bits (180), Expect = 5e-13
Identities = 112/425 (26%), Positives = 155/425 (36%), Gaps = 105/425 (24%)
Query: 2 SALLQDPMIAGQVSKPLLSVRSEMNAELRGE-------DKAATSDSELNE------PLLA 48
S + Q ++ G S P L+ S+ LR + AT EL P A
Sbjct: 162 SGIAQQAVLLGNTSSPALTA-SQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPA 220
Query: 49 PVESND--SEDTPSKLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAV 106
V++ ++ TP+ A P + P P S P P G QPL T Q +
Sbjct: 221 QVQNLTLRTQQTPA---AAASGPTPTQPVLP-----SLALKPTPGGSQPLPTPAQSRNTA 272
Query: 107 AGVMPGGPPALNQPILIPF-------NMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAG 159
G P + ++ P ++ G + G+ GL T+P L+A A A
Sbjct: 273 QASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAA---HPLIAPAYA- 328
Query: 160 GIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQ-------HPQPAPQAP 212
LQ Q +S+ Q Q +QQQ Q QQQQPPP ++ HPQ A +P
Sbjct: 329 -----QLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSP 383
Query: 213 -------SQSQQQPLQPTPPQQP----------PPASQQ--PPAPTSQLQQA-PQPQQHQ 252
S++ PL P P P P SQQ PP P + Q P+ H
Sbjct: 384 SVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHT 443
Query: 253 PHSHSQNQNQPSPTQQSSSPPQK------------------------PSQS------PGH 282
P Q+ + Q +SPPQ+ P Q PG
Sbjct: 444 PQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPG- 502
Query: 283 GLPSPLTP---PNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNA 339
GLP P +P P+P + A +SS + GN+ SS+ G Q N
Sbjct: 503 GLPVPTSPNIQPSPAHETGQGIVH----ALTDLSSPGMTSGNGNSASSIAGTAPQNGENK 558
Query: 340 QGQII 344
Q I
Sbjct: 559 PPQAI 563
Score = 34.7 bits (78), Expect = 0.30
Identities = 60/230 (26%), Positives = 87/230 (37%), Gaps = 22/230 (9%)
Query: 204 HPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQP 263
H QP+ A Q Q A QQ ++QLQ QQ S N+
Sbjct: 65 HRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQ-----ASLVSNRQ 119
Query: 264 SPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLA-SQAAAAAAAMSSIASSQAFG 322
T S+ Q P+QS L + P QL+N + + AAA+ A ++
Sbjct: 120 GSTSGSNVSAQAPAQSSSINLAA---SPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSS 176
Query: 323 NALSSLQG---VTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNA 379
AL++ Q + Q++ + T+ P G S A T QVQ +T L
Sbjct: 177 PALTASQAQMYLRAQMLIFTPTATVATV--QPELGTGSPARPPTPA-QVQNLT---LRTQ 230
Query: 380 QGQIIATVIGNQILPVINTQGITLSPIKPGQQ-LHQPSQT-SVGQAASQG 427
Q A PV+ + L P G Q L P+Q+ + QA+ G
Sbjct: 231 QTPAAAASGPTPTQPVL--PSLALKPTPGGSQPLPTPAQSRNTAQASPAG 278
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 73.6 bits (179), Expect = 6e-13
Identities = 125/444 (28%), Positives = 169/444 (38%), Gaps = 80/444 (18%)
Query: 90 PVGPQPLLTAQQLASA-VAGVMPG----GPPALNQPILIPFNMAGQLGGQQGLVLT---L 141
PV P L T A A V P G PA P L+ +MA G + +T +
Sbjct: 2620 PVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLV--SMATTQGVRAVTSVTASAV 2677
Query: 142 PTANLTNIQ----GLVAAAAAGGIMTLPLQNLQ-ATSSLNSQLQQLQLQLQQQQQQQQQQ 196
T NLT +Q LV + + LP + + A L Q QQ Q Q QQQQQQQQQQ
Sbjct: 2678 VTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQ 2737
Query: 197 PPPSTNQHPQ---------PAPQAPSQS------------------QQQPLQPTPPQQPP 229
Q Q P Q +QS Q+Q LQ PPQ PP
Sbjct: 2738 QQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQ-MPPQPPP 2796
Query: 230 PASQQ-PPAPTS--QLQQAPQPQQHQPHSHSQNQNQPS-------------------PTQ 267
P +Q PP PT+ Q+Q + PQQ P + +P PT
Sbjct: 2797 PQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTS 2856
Query: 268 QSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLA--SQAAAAAAAMSSIASSQAFGNAL 325
Q + Q +Q+P + PP +V+ P A S M+ S A G
Sbjct: 2857 QLQAQGQMQTQAPQPAQVALAKPP----VVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQ 2912
Query: 326 SSL-QGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQII 384
+ Q V Q V Q + + QAA G +Q Q IT Q +T Q
Sbjct: 2913 KAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQ-QKITAQQITTPGAQ-- 2969
Query: 385 ATVIGNQILPVINTQGITLSPIKPGQQL--HQPSQTSVGQAASQGNLLHLAHSQASMSQS 442
+ P + TQ +T +PI Q+L Q QT + Q A ++ AS+ Q
Sbjct: 2970 -QKVAYAAQPALKTQFLT-TPISQAQKLAGAQQVQTQI-QVAKLPQVVQQQTPVASIQQV 3026
Query: 443 PVRQASSSSSSSSSSSALSVGQLV 466
+S + + + A + GQ V
Sbjct: 3027 ASASQQASPQTVALTQATAAGQQV 3050
Score = 62.0 bits (149), Expect = 2e-09
Identities = 82/328 (25%), Positives = 119/328 (36%), Gaps = 50/328 (15%)
Query: 165 PLQNLQATSSLNSQLQQLQLQLQQQQQQQQQ---QPPPSTNQHPQPAPQAPSQSQQQPLQ 221
PL +Q S ++ + + L QQ+ QQ QPPP PQP P
Sbjct: 2471 PLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPPP-----PQPQP------------ 2513
Query: 222 PTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQS-- 279
P PPQQPPP QP A SQ P Q QP Q Q QP + P S
Sbjct: 2514 PPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAA 2573
Query: 280 ----------PGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQ 329
G +P+ N ++ N +A AA +++ +S AL++
Sbjct: 2574 VLAGTIKTSVTGTSMPTGAVSGN---VIVNTIAGVPAATFQSINKRLASPVAPGALTTPG 2630
Query: 330 GVTGQLVTNAQ--GQIIGTIPLMPNPGPSSQAASGTQGLQ-VQPITPQLLTNAQGQIIAT 386
G V + Q + +G+ P P S A TQG++ V +T + + T
Sbjct: 2631 GSAPAQVVHTQPPPRAVGS-PATATPDLVSMAT--TQGVRAVTSVTASAVVTTNLTPVQT 2687
Query: 387 VIGNQILPVINTQGITL--SPIKPG-------QQLHQPSQTSVGQAASQGNLLHLAHSQA 437
+ + V G+ L I P QQ Q Q Q Q Q
Sbjct: 2688 PARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 2747
Query: 438 SMSQSPVRQASSSSSSSSSSSALSVGQL 465
+ + S V+ + S + +VG+L
Sbjct: 2748 TTTTSQVQVPQIQGQAQSPAQIKAVGKL 2775
Score = 50.1 bits (118), Expect = 7e-06
Identities = 72/257 (28%), Positives = 99/257 (38%), Gaps = 45/257 (17%)
Query: 164 LPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPT 223
+PLQ L T+ QL Q+Q QQ Q PST P + S PL P
Sbjct: 503 VPLQQLMPTAQGGMPPTPQAAQLAGQRQSQQ-QYDPSTG-----PPVQNAASLHTPL-PQ 555
Query: 224 PPQQPPPASQQPPAPTSQLQQAPQPQ------QHQPHSHSQNQNQPSPTQQSSS---PPQ 274
P + PPA A +S LQ A QPQ Q Q +Q N P P SS PP
Sbjct: 556 LPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPS 615
Query: 275 KPSQ------SPGH------------------GLPSPLTPPNPLQLVNNPLASQAAAAAA 310
+P+Q +PG LP PP P L P +S ++ A
Sbjct: 616 QPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPL---PTSSTSSLAPV 672
Query: 311 AMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMP-NPGPSSQAASGTQGLQVQ 369
+ S S A + ++ T + ++ + G + P P +Q A+ +Q
Sbjct: 673 SGSGPGPSPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQD 732
Query: 370 PITPQL-LTNAQGQIIA 385
+T Q+ L N Q IA
Sbjct: 733 TLTEQITLENQVHQRIA 749
Score = 44.3 bits (103), Expect = 4e-04
Identities = 73/233 (31%), Positives = 90/233 (38%), Gaps = 44/233 (18%)
Query: 79 QHQASQTHPPFPVGPQPLLTAQQLA----SAVAGVMPGGPPALNQPILIPFNMAGQLGGQ 134
Q A QT PV Q LL +Q A A+ GP A+ Q I Q
Sbjct: 2912 QKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKIT----------AQ 2961
Query: 135 QGLVLTLPTANLTNIQGLVAAAAAGGIMT--LPLQNLQATSSLNSQLQQLQLQLQQQQQQ 192
Q +T P A Q VA AA + T L QA +Q Q Q+Q+ + Q
Sbjct: 2962 Q---ITTPGA-----QQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQV 3013
Query: 193 QQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQP---PAPTSQLQQAPQP- 248
QQQ P ++ Q Q S SQQ Q Q A QQ PA T+ Q Q
Sbjct: 3014 VQQQTPVASIQ------QVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKL 3067
Query: 249 -QQHQPHSHS---QNQNQPSPTQ---QSSSPPQKPS---QSPGHGLPSPLTPP 291
QQ + S Q P+P Q S SP Q+P + P L +P PP
Sbjct: 3068 IQQQVVTTASAPLQTPGAPNPAQVPASSDSPSQQPKLQMRVPAVRLKTPTKPP 3120
Score = 43.9 bits (102), Expect = 5e-04
Identities = 111/480 (23%), Positives = 157/480 (32%), Gaps = 96/480 (20%)
Query: 69 PALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALN---------- 118
PA++ P P PP P P P L Q A + P GPPA+
Sbjct: 2501 PAVAQPPPPQPQP-----PPPPQQPPPPLPQPQAAGSQP---PAGPPAVQPQPQPQPQTQ 2552
Query: 119 -QPILIPFNM--AGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATS-- 173
QP+ P A GG ++ ++T + A +G ++ + + A +
Sbjct: 2553 PQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTG-TSMPTGAVSGNVIVNTIAGVPAATFQ 2611
Query: 174 SLNSQLQQ-------LQLQLQQQQQQQQQQPPPSTNQHPQPA-PQAPSQSQQQPLQP--- 222
S+N +L Q QPPP P A P S + Q ++
Sbjct: 2612 SINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTS 2671
Query: 223 -----------TPPQQP-----PPASQ----QPPAPT----------------SQLQQAP 246
TP Q P P SQ Q P T Q QQ
Sbjct: 2672 VTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQ 2731
Query: 247 QPQQHQPHSHSQNQNQPSPTQQSSSPP-QKPSQSPGH-GLPSPLTPPNPLQLVNN----- 299
Q QQ Q Q Q Q + T Q P Q +QSP LTP + +++
Sbjct: 2732 QQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMP 2791
Query: 300 -----PLASQAAAAAAAMSSIASSQAFGNALSSLQGVT----GQLVTNAQGQIIGTIPLM 350
P A A A + +SQ L VT G L+T + L
Sbjct: 2792 PQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLT 2851
Query: 351 PNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVI---GNQILPVINTQGITLSPIK 407
P QA Q QP L + A V+ G LP +N GI+ +
Sbjct: 2852 RVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLP-MNVAGIS---VA 2907
Query: 408 PGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVS 467
GQ QT V Q LL L Q ++ Q Q ++ ++ ++ Q+ +
Sbjct: 2908 IGQPQKAAGQTVVAQPVHMQQLLKL--KQQAVQQQKAIQPQAAQGPAAVQQKITAQQITT 2965
Score = 43.1 bits (100), Expect = 9e-04
Identities = 94/353 (26%), Positives = 135/353 (38%), Gaps = 78/353 (22%)
Query: 180 QQLQLQLQQ---------QQQQQQQQPPPSTNQHPQP-----APQAPSQSQQQPLQPTPP 225
Q +Q QLQ+ ++Q PPPS P APQ+PS QQ + +P
Sbjct: 8 QNVQHQLQRSRACPGSEGEEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQIQQLMNRSPA 67
Query: 226 -------------------QQPPPASQQPPAPTSQ-LQQAPQPQQHQPHSHSQNQ-NQPS 264
QQ A P+PTS Q + QP++ + S S Q P
Sbjct: 68 TGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHGSPSYIQVTSPL 127
Query: 265 PTQQSSSPPQKPSQSPGHGLPSPLT-PPNP-LQLVNNPLASQAAAAAAAMSSIASSQAFG 322
Q + P +PS PG L + P P L L ++ A+ + I+ S + G
Sbjct: 128 SQQVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQISLSPSSG 187
Query: 323 N--ALSSLQGVTGQLVTNAQGQII--GTI-------PLMPNP---------GPSSQAASG 362
G+T Q+ AQ Q+ GT P P+ GP S AA+G
Sbjct: 188 GHFVFQDGSGLT-QIAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQSPAAAG 246
Query: 363 TQGLQVQPI-TPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSVG 421
GL QP+ +P +T A + QI +I Q + + G L +P +G
Sbjct: 247 GAGL--QPLASPSHITTAN-------LPPQISSIIQGQLVQQQQVLQGPPLPRP----LG 293
Query: 422 QAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAG 474
+ G LL A A + S +S S +A+ G L S P T+ G
Sbjct: 294 FERTPGVLLPGAGGAAGFGMT-----SPPPPTSPSRTAVPPG-LSSLPLTSVG 340
Score = 43.1 bits (100), Expect = 9e-04
Identities = 82/350 (23%), Positives = 118/350 (33%), Gaps = 67/350 (19%)
Query: 199 PSTNQHPQPAPQAPSQSQQQPLQPTPPQ---QPPPASQQPPAPTSQLQQAPQPQQHQPHS 255
PST+ AP S + Q PL+ PP P ++ AP Q + +HQP S
Sbjct: 1444 PSTHPPRTAAPTTASAAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPRHQPAS 1503
Query: 256 HSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSI 315
S P+ + + + +PG P P P + A +A +
Sbjct: 1504 ASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAP-----------SHAAGQSALPQRLV 1552
Query: 316 ASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQL 375
SQA S G+++ L GP S+ A QP TP
Sbjct: 1553 LPSQAQARLPS--------------GEVVKIAQLASITGPQSRVA--------QPETPVT 1590
Query: 376 L-------TNAQGQIIATVIGNQILPVINTQGITLSPIK-PGQQLHQPSQTSVGQAASQG 427
L T + Q+ G + QG L + PGQ + V Q SQ
Sbjct: 1591 LQFQGSKFTLSHSQLRQLTAGQP----LQLQGSVLQIVSAPGQPYLRAPGPVVMQTVSQA 1646
Query: 428 NLLH--LAHSQASMSQSPVRQASS-SSSSSSSSSALSVGQLVSNPQTA---AGEVDGVNL 481
+H L + SP + +AL+VG+ P TA A + G
Sbjct: 1647 GAVHGALGSKPPAGGPSPAPLTPQVGVPGRVAVNALAVGE----PGTASKPASPIGGPTQ 1702
Query: 482 EEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSH 531
EE K R L L Q + ++ P Y + + R L SH
Sbjct: 1703 EE--------KTRLLKERLDQIYLVNERRCSQAPVYGRD-LLRICALPSH 1743
Score = 37.0 bits (84), Expect = 0.061
Identities = 59/213 (27%), Positives = 83/213 (38%), Gaps = 42/213 (19%)
Query: 199 PSTNQHPQPAPQA--PSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAP--QPQQHQPH 254
P QH +A S+ ++QP P PP P PA+ P+ + Q+P Q QQ
Sbjct: 7 PQNVQHQLQRSRACPGSEGEEQPAHPNPP--PSPAAPFAPSASPSAPQSPSYQIQQLMNR 64
Query: 255 SHSQNQNQPSPTQQSSSPPQKPSQS---PGHGLPSPLTP---------------PNPLQL 296
S + QN + T QS P +Q LPSP +P P+ +Q
Sbjct: 65 SPATGQN-VNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHGSPSYIQ- 122
Query: 297 VNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNA-------QGQIIGTIPL 349
V +PL+ Q + S QA N + G L +++ ++ I L
Sbjct: 123 VTSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQISL 182
Query: 350 MPNPGPS--SQAASG----TQGLQVQ---PITP 373
P+ G Q SG QG QVQ P TP
Sbjct: 183 SPSSGGHFVFQDGSGLTQIAQGAQVQLQHPGTP 215
Score = 35.4 bits (80), Expect = 0.18
Identities = 61/236 (25%), Positives = 91/236 (38%), Gaps = 39/236 (16%)
Query: 171 ATSSLNSQLQQLQLQLQQQQQQQ---QQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQ 227
AT S N + + Q Q + QP +++ PA A ++Q Q + P Q
Sbjct: 1472 ATFSANPEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHPAKLRAQTTA-QASTPGQ 1530
Query: 228 PPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSP 287
PPP QP AP+ Q+ PQ+ S +Q + S K +Q L S
Sbjct: 1531 PPP---QPQAPSHAAGQSALPQRLVLPSQAQ-------ARLPSGEVVKIAQ-----LASI 1575
Query: 288 LTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTI 347
P + + P+ Q + +S Q LQG Q+V +A GQ
Sbjct: 1576 TGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPLQLQGSVLQIV-SAPGQ----- 1629
Query: 348 PLMPNPGP-----SSQA-----ASGTQ----GLQVQPITPQLLTNAQGQIIATVIG 389
P + PGP SQA A G++ G P+TPQ+ + + A +G
Sbjct: 1630 PYLRAPGPVVMQTVSQAGAVHGALGSKPPAGGPSPAPLTPQVGVPGRVAVNALAVG 1685
Score = 33.1 bits (74), Expect = 0.88
Identities = 68/282 (24%), Positives = 97/282 (34%), Gaps = 61/282 (21%)
Query: 193 QQQQPPPSTNQHPQPA-PQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQH 251
++QQ PST Q P+ Q Q P Q P + PQ Q
Sbjct: 466 KRQQAMPSTGMAEQSKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPPTPQAAQL 525
Query: 252 QPHSHSQNQNQPS---PTQQSSS----PPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQ 304
SQ Q PS P Q ++S PQ P + P G+P+
Sbjct: 526 AGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPT------------------ 567
Query: 305 AAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTI----PLMPNPGPSSQAA 360
AA+S S+LQ V AQ Q+ + P +P P P S
Sbjct: 568 -----AALS------------SALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQ- 609
Query: 361 SGTQGLQVQPITP-QLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTS 419
L + P P QL + V +Q+ + T P+ P +P TS
Sbjct: 610 -----LPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTS 664
Query: 420 VGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALS 461
S +L + S + SP R + + SS+++ ALS
Sbjct: 665 -----STSSLAPV--SGSGPGPSPARSSPVNRPSSATNKALS 699
Score = 32.7 bits (73), Expect = 1.2
Identities = 57/268 (21%), Positives = 91/268 (33%), Gaps = 25/268 (9%)
Query: 47 LAPVESNDSEDTP--SKLFGARGNPALSDPGT-PDQHQASQTHPPFPVGPQPLLTAQQLA 103
L P TP ++L G R + DP T P A+ H P P P L A
Sbjct: 508 LMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPT 567
Query: 104 SAVAGVMPGGPPALNQPILIPFNMAGQLG---GQQGLVLTLPTANLTNIQGLVAAAAAGG 160
+A++ + QP ++ Q+ Q + + P ++ I A A
Sbjct: 568 AALSSALQFA----QQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALH 623
Query: 161 IMTLPLQNLQAT--SSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQ-------HPQPAP-- 209
+ T +QA+ SSL + +L + + P ST+ P P+P
Sbjct: 624 VPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPAR 683
Query: 210 ----QAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSP 265
PS + + L P + P + P P S Q A Q + ++ +
Sbjct: 684 SSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQITLENQ 743
Query: 266 TQQSSSPPQKPSQSPGHGLPSPLTPPNP 293
Q + +K LP P P
Sbjct: 744 VHQRIAELRKAGLWSQRRLPKLQEAPRP 771
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 72.4 bits (176), Expect = 1e-12
Identities = 71/236 (30%), Positives = 88/236 (37%), Gaps = 19/236 (8%)
Query: 69 PALSDPGT---PDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPF 125
P PGT P Q + P P+GP AQQ S GP AL QP +
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKP-PAQQTGSEKPSSEQPGPKALAQPPGVGK 399
Query: 126 NMAGQLGGQQGLVLTLPTAN-LTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQL 184
A Q G + + T L GL + A A G P+Q QQ
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ---PGPGKIPAQQAGP 456
Query: 185 QLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQP---TPPQQ------PPPASQQP 235
QQ +PP +P PQ P ++ P QP PP Q PPP P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516
Query: 236 PAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPP 291
P+ Q + +P QP S + QPSP + S+ KP G G PL PP
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG--KPLQPP 570
Score = 45.8 bits (107), Expect = 1e-04
Identities = 91/378 (24%), Positives = 130/378 (34%), Gaps = 66/378 (17%)
Query: 45 PLLAPVESNDSEDTPSKLFGA-RGNPALSDPGTPDQHQASQTHPPF-------PVGPQPL 96
P P + S PS+ G+ + P P P Q T PP P QP
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545
Query: 97 L---TAQQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQQGLVLTL-PTANLTNIQGL 152
+AQQ V+ G P L P + P + + QGL T+ P N T +
Sbjct: 546 PAKPSAQQSTKPVSQTGSGKP--LQPPTVSP---SAKQPPSQGLPKTICPLCNTTELLLH 600
Query: 153 VAAAAAGGIMT------LPLQNLQATSSLNSQLQQLQLQLQQQQQ------QQQQQPPPS 200
V A T L L + L L Q ++ P P
Sbjct: 601 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660
Query: 201 TNQHPQPAPQAPSQSQQQPLQPTP---------------PQQPPPASQQPPAPTSQLQQA 245
P A S+S QP Q +P P++PPP +QP S +A
Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA 720
Query: 246 PQPQQHQPHSHSQNQNQPS-PTQQSSSP--PQKPSQ----SPGHGLPSPLTPPNPLQLVN 298
QP + S +PS P++Q +P KP Q P L S + + +
Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Query: 299 NPLASQA---AAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQII----GTIPLMP 351
+ + SQA S SQ+F TG+ V+ + I ++
Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSF--------PPTGEKVSPFDSKAIPRPASDSKIIS 832
Query: 352 NPGPSSQAASGTQGLQVQ 369
+PGPSS++ Q VQ
Sbjct: 833 HPGPSSESKGQKQVDPVQ 850
Score = 42.0 bits (97), Expect = 0.002
Identities = 73/308 (23%), Positives = 95/308 (30%), Gaps = 12/308 (3%)
Query: 165 PLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTP 224
P+Q T + LQ + Q +Q + + P+P P Q P +P P
Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP-P 315
Query: 225 PQQP-----PPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQS 279
QQP P +PPA S L + Q Q P Q P + P+Q
Sbjct: 316 AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375
Query: 280 PGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNA 339
G PS P P L P + A + +Q G Q Q A
Sbjct: 376 TGSEKPSS-EQPGPKALAQPPGVGKTPAQQPGPAK-PPTQQVGTPKPLAQQPGLQSPAKA 433
Query: 340 QGQIIGTIPLMPNPG--PSSQAASG-TQGLQVQPITPQLLTNAQGQIIATVIGNQILPVI 396
G T P PG P+ QA G T Q P P + G P
Sbjct: 434 PGP-TKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ 492
Query: 397 NTQGITLSPIKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSS 456
+PG P Q + + Q SQ S P Q S + S+
Sbjct: 493 QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ 552
Query: 457 SSALSVGQ 464
S V Q
Sbjct: 553 QSTKPVSQ 560
Score = 40.4 bits (93), Expect = 0.006
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 17/97 (17%)
Query: 196 QPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPAS-QQPPAPTSQL-----QQAPQPQ 249
QP P H Q P AP + P QP Q PP ++ Q PPAP + +AP +
Sbjct: 951 QPGP----HSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
Query: 250 QHQPHS-------HSQNQNQPSPTQQSSSPPQKPSQS 279
+ +P + ++ + +P P + S S +P ++
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKA 1043
Score = 35.8 bits (81), Expect = 0.14
Identities = 54/259 (20%), Positives = 81/259 (31%), Gaps = 41/259 (15%)
Query: 169 LQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQP 228
L A SS+ ++ L + Q++ Q Q P+ +
Sbjct: 163 LSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIK-------------- 208
Query: 229 PPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLP--S 286
PP QQPP P P+Q P Q+ + S P + SQ PG G P
Sbjct: 209 PPLQQQPPKPI--------PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQG 260
Query: 287 PLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGT 346
P P PL A+ + I ++ +L S Q
Sbjct: 261 PTQTPQ-TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ------------ 307
Query: 347 IPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPI 406
P PG G + Q P P + + +A G + P + G T P
Sbjct: 308 ---QPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT-VKPPVQPPGTTKPPA 363
Query: 407 KPGQQLHQPSQTSVGQAAS 425
+P P+Q + + S
Sbjct: 364 QPLGPAKPPAQQTGSEKPS 382
Score = 35.0 bits (79), Expect = 0.23
Identities = 43/186 (23%), Positives = 67/186 (36%), Gaps = 40/186 (21%)
Query: 204 HPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQP 263
HP P+ ++ Q Q P+Q ++P A Q + +P+P
Sbjct: 833 HPGPSSESKGQKQVDPVQKK--EEPKKA---------QTKMSPKP-------------DA 868
Query: 264 SPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGN 323
P + S P P + G +P+P P P + Q+ + + SI +
Sbjct: 869 KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE--------QSRRFSLNLGSITDAPK-SQ 919
Query: 324 ALSSLQGVTGQLV---TNAQGQIIGTIPLMPNPGPSSQAASGTQGLQV----QPITPQLL 376
+ + VTG+L + Q I PGP SQ+ G Q QP T Q
Sbjct: 920 PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP 979
Query: 377 TNAQGQ 382
+ GQ
Sbjct: 980 PKSTGQ 985
Score = 35.0 bits (79), Expect = 0.23
Identities = 20/88 (22%), Positives = 33/88 (37%)
Query: 185 QLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQ 244
Q Q Q PP + PAP +++ P + P A Q P ++ ++
Sbjct: 966 QAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEK 1025
Query: 245 APQPQQHQPHSHSQNQNQPSPTQQSSSP 272
P P + ++ Q PT+ SP
Sbjct: 1026 KPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053
Score = 35.0 bits (79), Expect = 0.23
Identities = 33/105 (31%), Positives = 39/105 (37%), Gaps = 15/105 (14%)
Query: 190 QQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQ 249
Q + Q PP T Q P +Q Q P P Q APTS QQ+ Q
Sbjct: 3861 QTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQ---------APTSYTQQSHFEQ 3911
Query: 250 Q---HQPHSHSQNQNQPSPTQQSSSPPQ---KPSQSPGHGLPSPL 288
Q HQ S Q Q S PQ P+ P + LPS +
Sbjct: 3912 QTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQM 3956
Score = 34.3 bits (77), Expect = 0.40
Identities = 21/67 (31%), Positives = 26/67 (38%), Gaps = 7/67 (10%)
Query: 189 QQQQQQQQPPPSTNQHPQPAPQAP-------SQSQQQPLQPTPPQQPPPASQQPPAPTSQ 241
Q++ Q P S + PA P S Q P P PP PPP PP P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 242 LQQAPQP 248
+P+P
Sbjct: 2429 PPTSPKP 2435
Score = 33.9 bits (76), Expect = 0.52
Identities = 68/322 (21%), Positives = 108/322 (33%), Gaps = 54/322 (16%)
Query: 203 QHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQ 262
Q P P P P P P PP PP + + P +L A P + +
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE 2463
Query: 263 PSPTQQSSS-------------PPQKPSQSPGHGL-----PSPLTPPNPLQLVNNPLASQ 304
+ +S+ P KPS P GL P P PP + P+ Q
Sbjct: 2464 TTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS-GLVFTHRPEPSKPP----IAPKPVIPQ 2518
Query: 305 AAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIG-TIPLMPNPGPS------- 356
+ I LS +T LVT+A ++ T PL P+ S
Sbjct: 2519 LPTTTQKPTDIHPKP---TGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
Query: 357 -----------SQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSP 405
S+ + T Q IT L + +++ ++P + I P
Sbjct: 2576 LTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEI---P 2632
Query: 406 IKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVG-- 463
I Q + A + S++Q + S + S++ S+A SVG
Sbjct: 2633 ISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLS 2692
Query: 464 --QLVSNPQTAAGEVDGVNLEE 483
+ P+ A +D ++LE+
Sbjct: 2693 SISITIPPEPLA--LDNIHLEK 2712
Score = 33.5 bits (75), Expect = 0.68
Identities = 68/357 (19%), Positives = 115/357 (32%), Gaps = 96/357 (26%)
Query: 2 SALLQDPMIAGQVSKPLLSVRSEMNAELRGEDKAATSDSELNEP--------LLAPVESN 53
SA + P A +SKP + +E +DKA +D + +P L++ +
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVPSE---QDKAPVADDKPKQPKMVKPTTDLVSSSSAT 773
Query: 54 DSEDTPSKLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGG 113
D PS ++ + P D + SQ+ PP T ++++ + +P
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP---------TGEKVSPFDSKAIPR- 823
Query: 114 PPALNQPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATS 173
PA + I+ + + GQ+
Sbjct: 824 -PASDSKIISHPGPSSESKGQK-------------------------------------- 844
Query: 174 SLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQ 233
Q+ +Q + + ++ Q + P P P+ +P P PQQ P +
Sbjct: 845 ----QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Query: 234 QP---PAPTSQLQQAPQPQQHQPHS-------------HSQNQN------QPSPTQQS-- 269
Q + AP+ Q P SQ N QP P QS
Sbjct: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 270 ------SSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQA 320
+ P +P S G + PP P + + P+ + A AA + QA
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSI--PVKKETKAPAAEKLEPKAEQA 1015
Score = 33.1 bits (74), Expect = 0.88
Identities = 46/176 (26%), Positives = 74/176 (42%), Gaps = 24/176 (13%)
Query: 150 QGLVAAAAAGGIMT--LPLQNLQATSSLNSQLQQLQLQLQQQ----QQQQQQQPPPSTNQ 203
+GL AAAAAGG + + + + + L QL + ++Q + Q P S
Sbjct: 14 EGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSV-- 71
Query: 204 HPQPAPQAPSQSQQQPLQPT-PPQQ---PPPASQ--QPPAPTSQLQQAPQPQQHQP-HSH 256
P A ++PS ++Q L + PP+Q PP + QP S+ + +Q P S
Sbjct: 72 -PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSP 130
Query: 257 SQNQNQPSPTQQSSSPPQKPSQSPG--------HGLPSPLTPPNPLQLVNNPLASQ 304
S + S ++ K S PG + S + NP L+++ ASQ
Sbjct: 131 STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQ 186
Score = 33.1 bits (74), Expect = 0.88
Identities = 42/165 (25%), Positives = 59/165 (35%), Gaps = 20/165 (12%)
Query: 227 QPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPS 286
Q PASQ P S +P+ S QP P PP P P P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP---PP 2425
Query: 287 PLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNA--QGQII 344
PL PP + P A S + ++ +A+++L+ T L +N +I
Sbjct: 2426 PLPPPTSPKPTILPKKKLTVA-----SPVTTATPLFDAVTTLE-TTAVLRSNGLPVTRIC 2479
Query: 345 GTIPLMPNPGPSS---------QAASGTQGLQVQPITPQLLTNAQ 380
T P P PSS + + +P+ PQL T Q
Sbjct: 2480 TTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQ 2524
Score = 31.2 bits (69), Expect = 3.4
Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 187 QQQQQQQQQQPPPSTNQHP-QPAPQAPSQSQQQPLQPTPPQ--QPPPASQQPPAPTSQLQ 243
Q++ Q PS + P +P P S S QP PP PPP PP P L
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 244 QAPQPQ 249
P+
Sbjct: 2429 PPTSPK 2434
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 72.4 bits (176), Expect = 1e-12
Identities = 71/236 (30%), Positives = 88/236 (37%), Gaps = 19/236 (8%)
Query: 69 PALSDPGT---PDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPF 125
P PGT P Q + P P+GP AQQ S GP AL QP +
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKP-PAQQTGSEKPSSEQPGPKALAQPPGVGK 399
Query: 126 NMAGQLGGQQGLVLTLPTAN-LTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQL 184
A Q G + + T L GL + A A G P+Q QQ
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ---PGPGKIPAQQAGP 456
Query: 185 QLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQP---TPPQQ------PPPASQQP 235
QQ +PP +P PQ P ++ P QP PP Q PPP P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516
Query: 236 PAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPP 291
P+ Q + +P QP S + QPSP + S+ KP G G PL PP
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG--KPLQPP 570
Score = 45.8 bits (107), Expect = 1e-04
Identities = 91/378 (24%), Positives = 130/378 (34%), Gaps = 66/378 (17%)
Query: 45 PLLAPVESNDSEDTPSKLFGA-RGNPALSDPGTPDQHQASQTHPPF-------PVGPQPL 96
P P + S PS+ G+ + P P P Q T PP P QP
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545
Query: 97 L---TAQQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQQGLVLTL-PTANLTNIQGL 152
+AQQ V+ G P L P + P + + QGL T+ P N T +
Sbjct: 546 PAKPSAQQSTKPVSQTGSGKP--LQPPTVSP---SAKQPPSQGLPKTICPLCNTTELLLH 600
Query: 153 VAAAAAGGIMT------LPLQNLQATSSLNSQLQQLQLQLQQQQQ------QQQQQPPPS 200
V A T L L + L L Q ++ P P
Sbjct: 601 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660
Query: 201 TNQHPQPAPQAPSQSQQQPLQPTP---------------PQQPPPASQQPPAPTSQLQQA 245
P A S+S QP Q +P P++PPP +QP S +A
Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA 720
Query: 246 PQPQQHQPHSHSQNQNQPS-PTQQSSSP--PQKPSQ----SPGHGLPSPLTPPNPLQLVN 298
QP + S +PS P++Q +P KP Q P L S + + +
Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Query: 299 NPLASQA---AAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQII----GTIPLMP 351
+ + SQA S SQ+F TG+ V+ + I ++
Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSF--------PPTGEKVSPFDSKAIPRPASDSKIIS 832
Query: 352 NPGPSSQAASGTQGLQVQ 369
+PGPSS++ Q VQ
Sbjct: 833 HPGPSSESKGQKQVDPVQ 850
Score = 42.0 bits (97), Expect = 0.002
Identities = 73/308 (23%), Positives = 95/308 (30%), Gaps = 12/308 (3%)
Query: 165 PLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTP 224
P+Q T + LQ + Q +Q + + P+P P Q P +P P
Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP-P 315
Query: 225 PQQP-----PPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQS 279
QQP P +PPA S L + Q Q P Q P + P+Q
Sbjct: 316 AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375
Query: 280 PGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNA 339
G PS P P L P + A + +Q G Q Q A
Sbjct: 376 TGSEKPSS-EQPGPKALAQPPGVGKTPAQQPGPAK-PPTQQVGTPKPLAQQPGLQSPAKA 433
Query: 340 QGQIIGTIPLMPNPG--PSSQAASG-TQGLQVQPITPQLLTNAQGQIIATVIGNQILPVI 396
G T P PG P+ QA G T Q P P + G P
Sbjct: 434 PGP-TKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ 492
Query: 397 NTQGITLSPIKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSS 456
+PG P Q + + Q SQ S P Q S + S+
Sbjct: 493 QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ 552
Query: 457 SSALSVGQ 464
S V Q
Sbjct: 553 QSTKPVSQ 560
Score = 40.4 bits (93), Expect = 0.006
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 17/97 (17%)
Query: 196 QPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPAS-QQPPAPTSQL-----QQAPQPQ 249
QP P H Q P AP + P QP Q PP ++ Q PPAP + +AP +
Sbjct: 951 QPGP----HSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
Query: 250 QHQPHS-------HSQNQNQPSPTQQSSSPPQKPSQS 279
+ +P + ++ + +P P + S S +P ++
Sbjct: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKA 1043
Score = 35.8 bits (81), Expect = 0.14
Identities = 54/259 (20%), Positives = 81/259 (31%), Gaps = 41/259 (15%)
Query: 169 LQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQP 228
L A SS+ ++ L + Q++ Q Q P+ +
Sbjct: 163 LSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIK-------------- 208
Query: 229 PPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLP--S 286
PP QQPP P P+Q P Q+ + S P + SQ PG G P
Sbjct: 209 PPLQQQPPKPI--------PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQG 260
Query: 287 PLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGT 346
P P PL A+ + I ++ +L S Q
Sbjct: 261 PTQTPQ-TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ------------ 307
Query: 347 IPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPI 406
P PG G + Q P P + + +A G + P + G T P
Sbjct: 308 ---QPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT-VKPPVQPPGTTKPPA 363
Query: 407 KPGQQLHQPSQTSVGQAAS 425
+P P+Q + + S
Sbjct: 364 QPLGPAKPPAQQTGSEKPS 382
Score = 35.0 bits (79), Expect = 0.23
Identities = 43/186 (23%), Positives = 67/186 (36%), Gaps = 40/186 (21%)
Query: 204 HPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQP 263
HP P+ ++ Q Q P+Q ++P A Q + +P+P
Sbjct: 833 HPGPSSESKGQKQVDPVQKK--EEPKKA---------QTKMSPKP-------------DA 868
Query: 264 SPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGN 323
P + S P P + G +P+P P P + Q+ + + SI +
Sbjct: 869 KPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE--------QSRRFSLNLGSITDAPK-SQ 919
Query: 324 ALSSLQGVTGQLV---TNAQGQIIGTIPLMPNPGPSSQAASGTQGLQV----QPITPQLL 376
+ + VTG+L + Q I PGP SQ+ G Q QP T Q
Sbjct: 920 PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP 979
Query: 377 TNAQGQ 382
+ GQ
Sbjct: 980 PKSTGQ 985
Score = 35.0 bits (79), Expect = 0.23
Identities = 20/88 (22%), Positives = 33/88 (37%)
Query: 185 QLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQ 244
Q Q Q PP + PAP +++ P + P A Q P ++ ++
Sbjct: 966 QAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEK 1025
Query: 245 APQPQQHQPHSHSQNQNQPSPTQQSSSP 272
P P + ++ Q PT+ SP
Sbjct: 1026 KPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053
Score = 35.0 bits (79), Expect = 0.23
Identities = 33/105 (31%), Positives = 39/105 (37%), Gaps = 15/105 (14%)
Query: 190 QQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQ 249
Q + Q PP T Q P +Q Q P P Q APTS QQ+ Q
Sbjct: 3861 QTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQ---------APTSYTQQSHFEQ 3911
Query: 250 Q---HQPHSHSQNQNQPSPTQQSSSPPQ---KPSQSPGHGLPSPL 288
Q HQ S Q Q S PQ P+ P + LPS +
Sbjct: 3912 QTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQM 3956
Score = 34.3 bits (77), Expect = 0.40
Identities = 21/67 (31%), Positives = 26/67 (38%), Gaps = 7/67 (10%)
Query: 189 QQQQQQQQPPPSTNQHPQPAPQAP-------SQSQQQPLQPTPPQQPPPASQQPPAPTSQ 241
Q++ Q P S + PA P S Q P P PP PPP PP P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 242 LQQAPQP 248
+P+P
Sbjct: 2429 PPTSPKP 2435
Score = 33.9 bits (76), Expect = 0.52
Identities = 68/322 (21%), Positives = 108/322 (33%), Gaps = 54/322 (16%)
Query: 203 QHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQ 262
Q P P P P P P PP PP + + P +L A P + +
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE 2463
Query: 263 PSPTQQSSS-------------PPQKPSQSPGHGL-----PSPLTPPNPLQLVNNPLASQ 304
+ +S+ P KPS P GL P P PP + P+ Q
Sbjct: 2464 TTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS-GLVFTHRPEPSKPP----IAPKPVIPQ 2518
Query: 305 AAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIG-TIPLMPNPGPS------- 356
+ I LS +T LVT+A ++ T PL P+ S
Sbjct: 2519 LPTTTQKPTDIHPKP---TGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
Query: 357 -----------SQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSP 405
S+ + T Q IT L + +++ ++P + I P
Sbjct: 2576 LTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEI---P 2632
Query: 406 IKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVG-- 463
I Q + A + S++Q + S + S++ S+A SVG
Sbjct: 2633 ISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLS 2692
Query: 464 --QLVSNPQTAAGEVDGVNLEE 483
+ P+ A +D ++LE+
Sbjct: 2693 SISITIPPEPLA--LDNIHLEK 2712
Score = 33.5 bits (75), Expect = 0.68
Identities = 68/357 (19%), Positives = 115/357 (32%), Gaps = 96/357 (26%)
Query: 2 SALLQDPMIAGQVSKPLLSVRSEMNAELRGEDKAATSDSELNEP--------LLAPVESN 53
SA + P A +SKP + +E +DKA +D + +P L++ +
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVPSE---QDKAPVADDKPKQPKMVKPTTDLVSSSSAT 773
Query: 54 DSEDTPSKLFGARGNPALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGG 113
D PS ++ + P D + SQ+ PP T ++++ + +P
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPP---------TGEKVSPFDSKAIPR- 823
Query: 114 PPALNQPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATS 173
PA + I+ + + GQ+
Sbjct: 824 -PASDSKIISHPGPSSESKGQK-------------------------------------- 844
Query: 174 SLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQ 233
Q+ +Q + + ++ Q + P P P+ +P P PQQ P +
Sbjct: 845 ----QVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Query: 234 QP---PAPTSQLQQAPQPQQHQPHS-------------HSQNQN------QPSPTQQS-- 269
Q + AP+ Q P SQ N QP P QS
Sbjct: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 270 ------SSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQA 320
+ P +P S G + PP P + + P+ + A AA + QA
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSI--PVKKETKAPAAEKLEPKAEQA 1015
Score = 33.1 bits (74), Expect = 0.88
Identities = 46/176 (26%), Positives = 74/176 (42%), Gaps = 24/176 (13%)
Query: 150 QGLVAAAAAGGIMT--LPLQNLQATSSLNSQLQQLQLQLQQQ----QQQQQQQPPPSTNQ 203
+GL AAAAAGG + + + + + L QL + ++Q + Q P S
Sbjct: 14 EGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSV-- 71
Query: 204 HPQPAPQAPSQSQQQPLQPT-PPQQ---PPPASQ--QPPAPTSQLQQAPQPQQHQP-HSH 256
P A ++PS ++Q L + PP+Q PP + QP S+ + +Q P S
Sbjct: 72 -PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSP 130
Query: 257 SQNQNQPSPTQQSSSPPQKPSQSPG--------HGLPSPLTPPNPLQLVNNPLASQ 304
S + S ++ K S PG + S + NP L+++ ASQ
Sbjct: 131 STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQ 186
Score = 33.1 bits (74), Expect = 0.88
Identities = 42/165 (25%), Positives = 59/165 (35%), Gaps = 20/165 (12%)
Query: 227 QPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPS 286
Q PASQ P S +P+ S QP P PP P P P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP---PP 2425
Query: 287 PLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNA--QGQII 344
PL PP + P A S + ++ +A+++L+ T L +N +I
Sbjct: 2426 PLPPPTSPKPTILPKKKLTVA-----SPVTTATPLFDAVTTLE-TTAVLRSNGLPVTRIC 2479
Query: 345 GTIPLMPNPGPSS---------QAASGTQGLQVQPITPQLLTNAQ 380
T P P PSS + + +P+ PQL T Q
Sbjct: 2480 TTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQ 2524
Score = 31.2 bits (69), Expect = 3.4
Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 187 QQQQQQQQQQPPPSTNQHP-QPAPQAPSQSQQQPLQPTPPQ--QPPPASQQPPAPTSQLQ 243
Q++ Q PS + P +P P S S QP PP PPP PP P L
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 244 QAPQPQ 249
P+
Sbjct: 2429 PPTSPK 2434
>gi|238859557 regulatory factor X1 [Homo sapiens]
Length = 979
Score = 70.9 bits (172), Expect = 4e-12
Identities = 86/281 (30%), Positives = 114/281 (40%), Gaps = 58/281 (20%)
Query: 188 QQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQ 247
Q + Q PPPS QP PQAP Q+Q QP PP PP A Q P PT+ PQ
Sbjct: 4 QAYTELQAAPPPS-----QP-PQAPPQAQPQP----PPPPPPAAPQPPQPPTA--AATPQ 51
Query: 248 PQQHQPHSHSQNQNQPSPTQQS--SSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQA 305
PQ Q Q QP Q+ + P P+ S G P+P P +V
Sbjct: 52 PQYVTELQSPQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVV-------T 104
Query: 306 AAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQG 365
+ A +S S+A + +S GV Q+V QG + Q
Sbjct: 105 VSEGAMRASETVSEASPGSTASQTGVPTQVVQQVQG--------------TQQRLLVQTS 150
Query: 366 LQVQP--ITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSVGQA 423
+Q +P ++P LTN Q + Q LP TQ + + PG + Q S T G
Sbjct: 151 VQAKPGHVSPLQLTNIQ-------VPQQALP---TQRLVVQSAAPGSKGGQVSLTVHG-- 198
Query: 424 ASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQ 464
HS QSPV QA+SSSS ++ + +V Q
Sbjct: 199 ------TQQVHSPP--EQSPV-QANSSSSKTAGAPTGTVPQ 230
Score = 43.1 bits (100), Expect = 9e-04
Identities = 97/447 (21%), Positives = 148/447 (33%), Gaps = 50/447 (11%)
Query: 69 PALSDPGTPDQHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPFNMA 128
P P P Q Q PP P PQP Q +A A P L P A
Sbjct: 14 PPSQPPQAPPQAQPQPPPPPPPAAPQP----PQPPTAAATPQPQYVTELQS----PQPQA 65
Query: 129 GQLGGQQGLVLTLPTANLTN-----------IQGLVAAAAAGGIMTLPLQNLQATSSLNS 177
GGQ+ V LP + Q + + G M +A+ +
Sbjct: 66 QPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEASPGSTA 125
Query: 178 QLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQ--SQQQPLQPTPPQQPPPASQQP 235
+ Q+ QQ Q QQ+ T+ +P +P Q + Q P Q P Q+ S P
Sbjct: 126 SQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQVPQQALPTQRLVVQSAAP 185
Query: 236 PAPTSQLQQAPQ--PQQHQPHSHSQNQNQPSPTQQSSSPP-QKPSQSPGHGLPSPL---- 288
+ Q+ Q H P S Q S ++ + +P P Q HG+ +
Sbjct: 186 GSKGGQVSLTVHGTQQVHSPPEQSPVQANSSSSKTAGAPTGTVPQQLQVHGVQQSVPVTQ 245
Query: 289 -------TPPNPLQLVNNPLASQ------AAAAAAAMSSIASSQAFGNALSSLQGVTGQL 335
TP P PL Q A + + + + + ++G
Sbjct: 246 ERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQEVQQLQQVPVPHVYSSQVQYVEGGDASY 305
Query: 336 VTNAQGQIIGTIPLMP----NPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQ 391
+A + P P S A+GT P T Q + ++ G + V G+Q
Sbjct: 306 TASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASS-GSMPMYVSGSQ 364
Query: 392 ILPVINTQGITLSPIKPGQQL----HQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQA 447
++ + G S G G + S G A + + A
Sbjct: 365 VVASSTSTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGGYMLGSA 424
Query: 448 SSSSSSSSSSSALSVGQLVSNPQTAAG 474
S S S ++ +S +V L+ N +TA G
Sbjct: 425 SQSYSHTTRASPATVQWLLDNYETAEG 451
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 70.9 bits (172), Expect = 4e-12
Identities = 61/196 (31%), Positives = 82/196 (41%), Gaps = 7/196 (3%)
Query: 108 GVMPGGPPALNQPI---LIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTL 164
G + P L Q + + P + +L Q + AN+ + G ++ G M
Sbjct: 361 GTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVG 420
Query: 165 PLQNLQATSSLNSQLQQLQLQLQQQQQQQQ-QQPPPSTNQHPQPAPQAPSQSQQQPLQPT 223
+ Q + S+ +Q Q+QLQ QQQQQQQQ QQ Q Q Q Q QQQ Q
Sbjct: 421 SAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHH 480
Query: 224 PPQQPPPASQQPPAPTSQLQQAPQPQQH---QPHSHSQNQNQPSPTQQSSSPPQKPSQSP 280
Q Q +Q Q Q QQ Q H Q+Q+QPSP Q S Q S P
Sbjct: 481 MQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIP 540
Query: 281 GHGLPSPLTPPNPLQL 296
G P P + + Q+
Sbjct: 541 AIGSPQPASQQHQSQI 556
Score = 46.2 bits (108), Expect = 1e-04
Identities = 36/89 (40%), Positives = 38/89 (42%), Gaps = 11/89 (12%)
Query: 175 LNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQ- 233
L Q Q LQ Q+ QQQ QQQ Q Q Q Q QP+P Q P ASQ
Sbjct: 485 LQQQQQHLQQQINQQQLQQQLQQRLQLQQ---------LQHMQHQSQPSPRQHSPVASQI 535
Query: 234 QPPAPTSQLQQAPQPQQHQPHSHSQNQNQ 262
P P Q P QQHQ SQ Q Q
Sbjct: 536 TSPIPAIGSPQ-PASQQHQSQIQSQTQTQ 563
Score = 35.0 bits (79), Expect = 0.23
Identities = 36/86 (41%), Positives = 38/86 (44%), Gaps = 16/86 (18%)
Query: 166 LQNLQATSSLNSQLQQLQLQLQQ-QQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTP 224
LQ L QLQQ +LQLQQ Q Q Q QP P QH A Q S P P
Sbjct: 492 LQQQINQQQLQQQLQQ-RLQLQQLQHMQHQSQPSP--RQHSPVASQITS--------PIP 540
Query: 225 P-QQPPPASQQPPAPTSQLQQAPQPQ 249
P PASQQ SQ+Q Q Q
Sbjct: 541 AIGSPQPASQQ---HQSQIQSQTQTQ 563
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 70.9 bits (172), Expect = 4e-12
Identities = 61/196 (31%), Positives = 82/196 (41%), Gaps = 7/196 (3%)
Query: 108 GVMPGGPPALNQPI---LIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTL 164
G + P L Q + + P + +L Q + AN+ + G ++ G M
Sbjct: 366 GTVSASPQTLQQSLPRSIAPKPLTMRLPMNQIVTSVTIAANMPSNIGAPLISSMGTTMVG 425
Query: 165 PLQNLQATSSLNSQLQQLQLQLQQQQQQQQ-QQPPPSTNQHPQPAPQAPSQSQQQPLQPT 223
+ Q + S+ +Q Q+QLQ QQQQQQQQ QQ Q Q Q Q QQQ Q
Sbjct: 426 SAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHH 485
Query: 224 PPQQPPPASQQPPAPTSQLQQAPQPQQH---QPHSHSQNQNQPSPTQQSSSPPQKPSQSP 280
Q Q +Q Q Q QQ Q H Q+Q+QPSP Q S Q S P
Sbjct: 486 MQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIP 545
Query: 281 GHGLPSPLTPPNPLQL 296
G P P + + Q+
Sbjct: 546 AIGSPQPASQQHQSQI 561
Score = 46.2 bits (108), Expect = 1e-04
Identities = 36/89 (40%), Positives = 38/89 (42%), Gaps = 11/89 (12%)
Query: 175 LNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQ- 233
L Q Q LQ Q+ QQQ QQQ Q Q Q Q QP+P Q P ASQ
Sbjct: 490 LQQQQQHLQQQINQQQLQQQLQQRLQLQQ---------LQHMQHQSQPSPRQHSPVASQI 540
Query: 234 QPPAPTSQLQQAPQPQQHQPHSHSQNQNQ 262
P P Q P QQHQ SQ Q Q
Sbjct: 541 TSPIPAIGSPQ-PASQQHQSQIQSQTQTQ 568
Score = 35.0 bits (79), Expect = 0.23
Identities = 36/86 (41%), Positives = 38/86 (44%), Gaps = 16/86 (18%)
Query: 166 LQNLQATSSLNSQLQQLQLQLQQ-QQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTP 224
LQ L QLQQ +LQLQQ Q Q Q QP P QH A Q S P P
Sbjct: 497 LQQQINQQQLQQQLQQ-RLQLQQLQHMQHQSQPSP--RQHSPVASQITS--------PIP 545
Query: 225 P-QQPPPASQQPPAPTSQLQQAPQPQ 249
P PASQQ SQ+Q Q Q
Sbjct: 546 AIGSPQPASQQ---HQSQIQSQTQTQ 568
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.124 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,022,113
Number of Sequences: 37866
Number of extensions: 1782820
Number of successful extensions: 50712
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1091
Number of HSP's successfully gapped in prelim test: 1845
Number of HSP's that attempted gapping in prelim test: 15504
Number of HSP's gapped (non-prelim): 16020
length of query: 691
length of database: 18,247,518
effective HSP length: 109
effective length of query: 582
effective length of database: 14,120,124
effective search space: 8217912168
effective search space used: 8217912168
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.