Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 157739942
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157739942 gemin 5 [Homo sapiens]
(1508 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157739942 gemin 5 [Homo sapiens] 3099 0.0
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 95 4e-19
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 95 4e-19
gi|118402582 cell division cycle 20 [Homo sapiens] 71 7e-12
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 69 3e-11
gi|21536485 HIR histone cell cycle regulation defective homolog ... 65 4e-10
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 64 8e-10
gi|209969680 Fzr1 protein isoform 1 [Homo sapiens] 64 1e-09
gi|209969678 Fzr1 protein isoform 3 [Homo sapiens] 64 1e-09
gi|33620742 Fzr1 protein isoform 2 [Homo sapiens] 64 1e-09
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 62 3e-09
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 62 3e-09
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 62 3e-09
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 62 3e-09
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 61 9e-09
gi|19913367 transducin beta-like 1Y [Homo sapiens] 59 3e-08
gi|19913365 transducin beta-like 1Y [Homo sapiens] 59 3e-08
gi|15150805 transducin beta-like 1Y [Homo sapiens] 59 3e-08
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 59 5e-08
gi|23199987 WD repeat domain 5B [Homo sapiens] 59 5e-08
gi|169403944 WD repeat domain 26 isoform b [Homo sapiens] 57 2e-07
gi|55743153 WD repeat domain 26 isoform a [Homo sapiens] 57 2e-07
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 56 2e-07
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 56 3e-07
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 56 3e-07
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 56 3e-07
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 55 4e-07
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 55 4e-07
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 55 4e-07
gi|89886480 zinedin isoform 2 [Homo sapiens] 55 7e-07
>gi|157739942 gemin 5 [Homo sapiens]
Length = 1508
Score = 3099 bits (8034), Expect = 0.0
Identities = 1508/1508 (100%), Positives = 1508/1508 (100%)
Query: 1 MGQEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGEL 60
MGQEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGEL
Sbjct: 1 MGQEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGEL 60
Query: 61 VGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPR 120
VGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPR
Sbjct: 61 VGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPR 120
Query: 121 VKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIID 180
VKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIID
Sbjct: 121 VKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIID 180
Query: 181 ISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGC 240
ISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGC
Sbjct: 181 ISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGC 240
Query: 241 YLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLV 300
YLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLV
Sbjct: 241 YLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLV 300
Query: 301 SSCFGGELLQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRD 360
SSCFGGELLQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRD
Sbjct: 301 SSCFGGELLQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRD 360
Query: 361 VKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKN 420
VKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKN
Sbjct: 361 VKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKN 420
Query: 421 FWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGP 480
FWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGP
Sbjct: 421 FWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGP 480
Query: 481 PVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHT 540
PVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHT
Sbjct: 481 PVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHT 540
Query: 541 EISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLM 600
EISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLM
Sbjct: 541 EISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLM 600
Query: 601 ASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASY 660
ASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASY
Sbjct: 601 ASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASY 660
Query: 661 DGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRP 720
DGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRP
Sbjct: 661 DGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRP 720
Query: 721 PQGKKSIELEKKRLSQPKAKPKKKKKPTLRTPVKLESIDGNEEESMKENSGPVENGVSDQ 780
PQGKKSIELEKKRLSQPKAKPKKKKKPTLRTPVKLESIDGNEEESMKENSGPVENGVSDQ
Sbjct: 721 PQGKKSIELEKKRLSQPKAKPKKKKKPTLRTPVKLESIDGNEEESMKENSGPVENGVSDQ 780
Query: 781 EGEEQAREPELPCGLAPAVSREPVICTPVSSGFEKSKVTINNKVILLKKEPPKEKPETLI 840
EGEEQAREPELPCGLAPAVSREPVICTPVSSGFEKSKVTINNKVILLKKEPPKEKPETLI
Sbjct: 781 EGEEQAREPELPCGLAPAVSREPVICTPVSSGFEKSKVTINNKVILLKKEPPKEKPETLI 840
Query: 841 KKRKARSLLPLSTSLDHRSKEELHQDCLVLATAKHSRELNEDVSADVEERFHLGLFTDRA 900
KKRKARSLLPLSTSLDHRSKEELHQDCLVLATAKHSRELNEDVSADVEERFHLGLFTDRA
Sbjct: 841 KKRKARSLLPLSTSLDHRSKEELHQDCLVLATAKHSRELNEDVSADVEERFHLGLFTDRA 900
Query: 901 TLYRMIDIEGKGHLENGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPAAGYHV 960
TLYRMIDIEGKGHLENGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPAAGYHV
Sbjct: 901 TLYRMIDIEGKGHLENGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPAAGYHV 960
Query: 961 WLWAVEAFAKQLCFQDQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKARLRPEDP 1020
WLWAVEAFAKQLCFQDQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKARLRPEDP
Sbjct: 961 WLWAVEAFAKQLCFQDQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKARLRPEDP 1020
Query: 1021 VLKDLYLSWGTVLERDGHYAVAAKCYLGATCAYDAAKVLAKKGDAASLRTAAELAAIVGE 1080
VLKDLYLSWGTVLERDGHYAVAAKCYLGATCAYDAAKVLAKKGDAASLRTAAELAAIVGE
Sbjct: 1021 VLKDLYLSWGTVLERDGHYAVAAKCYLGATCAYDAAKVLAKKGDAASLRTAAELAAIVGE 1080
Query: 1081 DELSASLALRCAQELLLANNWVGAQEALQLHESLQGQRLVFCLLELLSRHLEEKQLSEGK 1140
DELSASLALRCAQELLLANNWVGAQEALQLHESLQGQRLVFCLLELLSRHLEEKQLSEGK
Sbjct: 1081 DELSASLALRCAQELLLANNWVGAQEALQLHESLQGQRLVFCLLELLSRHLEEKQLSEGK 1140
Query: 1141 SSSSYHTWNTGTEGPFVERVTAVWKSIFSLDTPEQYQEAFQKLQNIKYPSATNNTPAKQL 1200
SSSSYHTWNTGTEGPFVERVTAVWKSIFSLDTPEQYQEAFQKLQNIKYPSATNNTPAKQL
Sbjct: 1141 SSSSYHTWNTGTEGPFVERVTAVWKSIFSLDTPEQYQEAFQKLQNIKYPSATNNTPAKQL 1200
Query: 1201 LLHICHDLTLAVLSQQMASWDEAVQALLRAVVRSYDSGSFTIMQEVYSAFLPDGCDHLRD 1260
LLHICHDLTLAVLSQQMASWDEAVQALLRAVVRSYDSGSFTIMQEVYSAFLPDGCDHLRD
Sbjct: 1201 LLHICHDLTLAVLSQQMASWDEAVQALLRAVVRSYDSGSFTIMQEVYSAFLPDGCDHLRD 1260
Query: 1261 KLGDHQSPATPAFKSLEAFFLYGRLYEFWWSLSRPCPNSSVWVRAGHRTLSVEPSQQLDT 1320
KLGDHQSPATPAFKSLEAFFLYGRLYEFWWSLSRPCPNSSVWVRAGHRTLSVEPSQQLDT
Sbjct: 1261 KLGDHQSPATPAFKSLEAFFLYGRLYEFWWSLSRPCPNSSVWVRAGHRTLSVEPSQQLDT 1320
Query: 1321 ASTEETDPETSQPEPNRPSELDLRLTEEGERMLSTFKELFSEKHASLQNSQRTVAEVQET 1380
ASTEETDPETSQPEPNRPSELDLRLTEEGERMLSTFKELFSEKHASLQNSQRTVAEVQET
Sbjct: 1321 ASTEETDPETSQPEPNRPSELDLRLTEEGERMLSTFKELFSEKHASLQNSQRTVAEVQET 1380
Query: 1381 LAEMIRQHQKSQLCKSTANGPDKNEPEVEAEQPLCSSQSQCKEEKNEPLSLPELTKRLTE 1440
LAEMIRQHQKSQLCKSTANGPDKNEPEVEAEQPLCSSQSQCKEEKNEPLSLPELTKRLTE
Sbjct: 1381 LAEMIRQHQKSQLCKSTANGPDKNEPEVEAEQPLCSSQSQCKEEKNEPLSLPELTKRLTE 1440
Query: 1441 ANQRMAKFPESIKAWPFPDVLECCLVLLLIRSHFPGCLAQEMQQQAQELLQKYGNTKTYR 1500
ANQRMAKFPESIKAWPFPDVLECCLVLLLIRSHFPGCLAQEMQQQAQELLQKYGNTKTYR
Sbjct: 1441 ANQRMAKFPESIKAWPFPDVLECCLVLLLIRSHFPGCLAQEMQQQAQELLQKYGNTKTYR 1500
Query: 1501 RHCQTFCM 1508
RHCQTFCM
Sbjct: 1501 RHCQTFCM 1508
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 95.1 bits (235), Expect = 4e-19
Identities = 212/1058 (20%), Positives = 376/1058 (35%), Gaps = 259/1058 (24%)
Query: 22 AVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNL 81
A G F + A ++++ ++ E F++ + H + ++ ++ H +L
Sbjct: 23 AASGDRFAYCATLAIYIYQLDHRYNE------FKLHAIMSEHKKTITAISWCPH--NPDL 74
Query: 82 CATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNR 141
A+ S D V IW+V + V+ + + ++L W +D++ +G +F + +
Sbjct: 75 FASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVAFVSHRGPLFIWTISG 134
Query: 142 NDS-------QHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLR-- 192
DS H F+ +F H + V G+ DG + I K + H LR
Sbjct: 135 PDSGVIVHKDAHSFLSDICMF--RWHTHQKGKVVFGHIDGSLSIFHPGNKNQK-HVLRPE 191
Query: 193 -----GHDDEIHSIAWCPLPGEDCLSINQE------ETSEEAEITNGN---------AVA 232
+D + ++ W PL + L +N ++ + IT N +A
Sbjct: 192 SLEGTDEEDPVTALEWDPLSTDYLLVVNLHYGIRLVDSESLSCITTFNLPSAAASVQCLA 251
Query: 233 QAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWP 292
P G ++ S+ +RIW+ SR + LKL K+ + LH
Sbjct: 252 WVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKL--------------KKTGFHCLHVL 297
Query: 293 SNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSASSEG-------QNHSRIVFNLCPLQT 345
++ P + ++ + + YT S++SE QN + F+L P
Sbjct: 298 NSPPRK-----------KFSVQSPTKNHYT--SSTSEAVPPPTLTQNQA---FSLPPGHA 341
Query: 346 EDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFA--YSLAFSSVDIGSLAIGVGDGM 403
+ +D V +D+ + + L LG + F D LA DG
Sbjct: 342 -------VCCFLDGGVGLYDMGAKKWDF-LRDLGHVETIFDCKFKPDDPNLLATASFDGT 393
Query: 404 IRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQ 463
I+VW+ ++ Y G + + +L W P C+A GT +++ K Q
Sbjct: 394 IKVWDINTLTAVYTSP----GNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQ 449
Query: 464 ISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDIN 523
+ + ++ +AW + S + +C +G F I
Sbjct: 450 RFNEHGTNGIFCIAWS------------HKDSKRIATCSSDG--------------FCII 483
Query: 524 KLIRDTNSIKYKLPVHT-EISWKADGKIM-ALGNEDGSIEIFQIPNLKLICTIQQHHKLV 581
+ I KYK P W + K M A G ED ++ +
Sbjct: 484 RTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRV------------------- 524
Query: 582 NTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAK 641
Y +A+ S+ +P + SGHTAK
Sbjct: 525 ----------------YYVATSSD------------------------QPLKVFSGHTAK 544
Query: 642 ITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSG 701
+ V WSP +G L S S DGT ++WD ++ + GH + + W+ P + SG
Sbjct: 545 VFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISG 604
Query: 702 ADDFCVHKWLT-------SMQDHSRPPQGKKSIELEKKRLSQPKAKPKKKKKPTLR---- 750
+ D+ + W T ++ DH G S+P + T+R
Sbjct: 605 SWDYTIKVWDTREGTCVDTVYDHGADVYGLTC------HPSRPFTMASCSRDSTVRLWSL 658
Query: 751 ----TPVKLESIDGNEEESMKENSGPVENGVSDQEGEEQAREPELPCGLAPAVSREPVIC 806
TPV++ + E + N+ + A EP P P++C
Sbjct: 659 TALVTPVQINILADRSWEEIIGNT-------------DYAIEPGTP----------PLLC 695
Query: 807 TPVSSGF--EKSKVTINNKVILLK-----KEPPKEKPE----TLIKKRKARSLLPLSTSL 855
VS E K+T N++V L+ PP + K + SLLP
Sbjct: 696 GKVSRDIRQEIEKLTANSQVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLP----- 750
Query: 856 DHRSKEELHQDCLVLATAKHSRELNEDVSADVEERFHLGLFTDRATLYRMIDIEGKGHLE 915
+ K +H L+ ++EL + +G+ L +I HL
Sbjct: 751 QNYCKGIMHLKHLIKFRTSEAQELTTVKMSKFGG--GIGVPAKEERLKEAAEI----HLR 804
Query: 916 NGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPAAGYHVWLWAVEAFAKQLCFQ 975
G + + +LM+ G+ D +++AP W ++ A QL Q
Sbjct: 805 LGQIQRYCELMVELGE--------------WDKALSIAPGVSVKYWKKLMQRRADQL-IQ 849
Query: 976 DQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKA 1013
+ + ++I V + V S +EA+ +A+A
Sbjct: 850 EDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQA 887
Score = 75.9 bits (185), Expect = 3e-13
Identities = 81/327 (24%), Positives = 131/327 (40%), Gaps = 46/327 (14%)
Query: 10 PSPNWYCARCSDAVP------GGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGH 63
P+ N Y + S+AVP F +V G G + + +L GH
Sbjct: 310 PTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRDL-GH 368
Query: 64 TERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKD 123
E + F P NL AT+S DGT+K+WD+ T T V ++ I +L W+P +
Sbjct: 369 VETI--FDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLN 426
Query: 124 LIVSGDEKGVVFCYWFNRNDSQHLFIEPRT--IFCLTCSPHHEDLVAIGYKDGIVVIIDI 181
I G + F + + F E T IFC+ S +A DG +I I
Sbjct: 427 CIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTI 486
Query: 182 SKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETS-----------EEAEITNGNA 230
G+V+H+ + H + W +D ++ E+T+ + ++ +G+
Sbjct: 487 D--GKVLHKYK-HPAAVFGCDWSQ-NNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHT 542
Query: 231 -----VAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERL 285
V +P+ +G L +GS D T+RIW ++ + IL RG
Sbjct: 543 AKVFHVKWSPLREG-ILCSGSDDGTVRIWDYTQDACINILNGHTAPVRG----------- 590
Query: 286 WLTLHWPSNQPTQLVSSCFGGELLQWD 312
L W + P L+S + + WD
Sbjct: 591 ---LMWNTEIPYLLISGSWDYTIKVWD 614
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 95.1 bits (235), Expect = 4e-19
Identities = 212/1058 (20%), Positives = 376/1058 (35%), Gaps = 259/1058 (24%)
Query: 22 AVPGGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNL 81
A G F + A ++++ ++ E F++ + H + ++ ++ H +L
Sbjct: 47 AASGDRFAYCATLAIYIYQLDHRYNE------FKLHAIMSEHKKTITAISWCPH--NPDL 98
Query: 82 CATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNR 141
A+ S D V IW+V + V+ + + ++L W +D++ +G +F + +
Sbjct: 99 FASGSTDNLVIIWNVAEQKVIAKLDSTKGIPASLSWCWNAEDVVAFVSHRGPLFIWTISG 158
Query: 142 NDS-------QHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLR-- 192
DS H F+ +F H + V G+ DG + I K + H LR
Sbjct: 159 PDSGVIVHKDAHSFLSDICMF--RWHTHQKGKVVFGHIDGSLSIFHPGNKNQK-HVLRPE 215
Query: 193 -----GHDDEIHSIAWCPLPGEDCLSINQE------ETSEEAEITNGN---------AVA 232
+D + ++ W PL + L +N ++ + IT N +A
Sbjct: 216 SLEGTDEEDPVTALEWDPLSTDYLLVVNLHYGIRLVDSESLSCITTFNLPSAAASVQCLA 275
Query: 233 QAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWP 292
P G ++ S+ +RIW+ SR + LKL K+ + LH
Sbjct: 276 WVPSAPGMFITGDSQVGVLRIWNVSRTTPIDNLKL--------------KKTGFHCLHVL 321
Query: 293 SNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSASSEG-------QNHSRIVFNLCPLQT 345
++ P + ++ + + YT S++SE QN + F+L P
Sbjct: 322 NSPPRK-----------KFSVQSPTKNHYT--SSTSEAVPPPTLTQNQA---FSLPPGHA 365
Query: 346 EDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFA--YSLAFSSVDIGSLAIGVGDGM 403
+ +D V +D+ + + L LG + F D LA DG
Sbjct: 366 -------VCCFLDGGVGLYDMGAKKWDF-LRDLGHVETIFDCKFKPDDPNLLATASFDGT 417
Query: 404 IRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQ 463
I+VW+ ++ Y G + + +L W P C+A GT +++ K Q
Sbjct: 418 IKVWDINTLTAVYTSP----GNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQ 473
Query: 464 ISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDIN 523
+ + ++ +AW + S + +C +G F I
Sbjct: 474 RFNEHGTNGIFCIAWS------------HKDSKRIATCSSDG--------------FCII 507
Query: 524 KLIRDTNSIKYKLPVHT-EISWKADGKIM-ALGNEDGSIEIFQIPNLKLICTIQQHHKLV 581
+ I KYK P W + K M A G ED ++ +
Sbjct: 508 RTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRV------------------- 548
Query: 582 NTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAK 641
Y +A+ S+ +P + SGHTAK
Sbjct: 549 ----------------YYVATSSD------------------------QPLKVFSGHTAK 568
Query: 642 ITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSG 701
+ V WSP +G L S S DGT ++WD ++ + GH + + W+ P + SG
Sbjct: 569 VFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISG 628
Query: 702 ADDFCVHKWLT-------SMQDHSRPPQGKKSIELEKKRLSQPKAKPKKKKKPTLR---- 750
+ D+ + W T ++ DH G S+P + T+R
Sbjct: 629 SWDYTIKVWDTREGTCVDTVYDHGADVYGLTC------HPSRPFTMASCSRDSTVRLWSL 682
Query: 751 ----TPVKLESIDGNEEESMKENSGPVENGVSDQEGEEQAREPELPCGLAPAVSREPVIC 806
TPV++ + E + N+ + A EP P P++C
Sbjct: 683 TALVTPVQINILADRSWEEIIGNT-------------DYAIEPGTP----------PLLC 719
Query: 807 TPVSSGF--EKSKVTINNKVILLK-----KEPPKEKPE----TLIKKRKARSLLPLSTSL 855
VS E K+T N++V L+ PP + K + SLLP
Sbjct: 720 GKVSRDIRQEIEKLTANSQVKKLRWFSECLSPPGGSDNLWNLVAVIKGQDDSLLP----- 774
Query: 856 DHRSKEELHQDCLVLATAKHSRELNEDVSADVEERFHLGLFTDRATLYRMIDIEGKGHLE 915
+ K +H L+ ++EL + +G+ L +I HL
Sbjct: 775 QNYCKGIMHLKHLIKFRTSEAQELTTVKMSKFGG--GIGVPAKEERLKEAAEI----HLR 828
Query: 916 NGHPELFHQLMLWKGDLKGVLQTAAERGELTDNLVAMAPAAGYHVWLWAVEAFAKQLCFQ 975
G + + +LM+ G+ D +++AP W ++ A QL Q
Sbjct: 829 LGQIQRYCELMVELGE--------------WDKALSIAPGVSVKYWKKLMQRRADQL-IQ 873
Query: 976 DQYVKAASHLLSIHKVYEAVELLKSNHFYREAIAIAKA 1013
+ + ++I V + V S +EA+ +A+A
Sbjct: 874 EDKDDVIPYCIAIGDVKKLVHFFMSRGQLKEALLVAQA 911
Score = 75.9 bits (185), Expect = 3e-13
Identities = 81/327 (24%), Positives = 131/327 (40%), Gaps = 46/327 (14%)
Query: 10 PSPNWYCARCSDAVP------GGLFGFAARTSVFLVRVGPGAGESPGTPPFRVIGELVGH 63
P+ N Y + S+AVP F +V G G + + +L GH
Sbjct: 334 PTKNHYTSSTSEAVPPPTLTQNQAFSLPPGHAVCCFLDGGVGLYDMGAKKWDFLRDL-GH 392
Query: 64 TERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKD 123
E + F P NL AT+S DGT+K+WD+ T T V ++ I +L W+P +
Sbjct: 393 VETI--FDCKFKPDDPNLLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLN 450
Query: 124 LIVSGDEKGVVFCYWFNRNDSQHLFIEPRT--IFCLTCSPHHEDLVAIGYKDGIVVIIDI 181
I G + F + + F E T IFC+ S +A DG +I I
Sbjct: 451 CIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCIIRTI 510
Query: 182 SKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETS-----------EEAEITNGNA 230
G+V+H+ + H + W +D ++ E+T+ + ++ +G+
Sbjct: 511 D--GKVLHKYK-HPAAVFGCDWSQ-NNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHT 566
Query: 231 -----VAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERL 285
V +P+ +G L +GS D T+RIW ++ + IL RG
Sbjct: 567 AKVFHVKWSPLREG-ILCSGSDDGTVRIWDYTQDACINILNGHTAPVRG----------- 614
Query: 286 WLTLHWPSNQPTQLVSSCFGGELLQWD 312
L W + P L+S + + WD
Sbjct: 615 ---LMWNTEIPYLLISGSWDYTIKVWD 638
>gi|118402582 cell division cycle 20 [Homo sapiens]
Length = 499
Score = 71.2 bits (173), Expect = 7e-12
Identities = 48/201 (23%), Positives = 92/201 (45%), Gaps = 31/201 (15%)
Query: 506 IVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQI 565
+ L ++ + S + DI +L++ +Y + ++W +G +A+G ++++ +
Sbjct: 200 VALDNSVYLWSASSGDILQLLQMEQPGEYI----SSVAWIKEGNYLAVGTSSAEVQLWDV 255
Query: 566 PNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESP 625
K + + H V ++SW+ SY+++SGS + I+ H+++
Sbjct: 256 QQQKRLRNMTSHSARVGSLSWN---------SYILSSGSRSGHIHHHDVRVA-------- 298
Query: 626 VTITEPYRTLSGHTAKITSVAWSPHHDGR-LVSASYDGTAQVWDALREE----PLCNFRG 680
TLSGH+ ++ + W+P DGR L S D VW + E PL F
Sbjct: 299 ---EHHVATLSGHSQEVCGLRWAP--DGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQ 353
Query: 681 HRGRLLCVAWSPLDPDCIYSG 701
H+G + VAW P + + +G
Sbjct: 354 HQGAVKAVAWCPWQSNVLATG 374
Score = 45.1 bits (105), Expect = 5e-04
Identities = 71/321 (22%), Positives = 126/321 (39%), Gaps = 66/321 (20%)
Query: 429 VTALCWHPTKEG-CLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSL 487
++++ W KEG LA GT +V L+D K + + T H V +L+W + +S
Sbjct: 229 ISSVAW--IKEGNYLAVGTSSAEVQLWDVQQQKRLR-NMTSHSARVGSLSWNSYI--LSS 283
Query: 488 GGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKAD 547
G + + V +H+ LSG + ++ L W D
Sbjct: 284 GSRSG------HIHHHDVRVAEHHVATLSGHSQEVCGL-----------------RWAPD 320
Query: 548 GKIMALGNEDGSIEIFQ--------IPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYL 599
G+ +A G D + ++ +P + T QH V ++W P S +
Sbjct: 321 GRHLASGGNDNLVNVWPSAPGEGGWVP----LQTFTQHQGAVKAVAWC------PWQSNV 370
Query: 600 MASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSAS 659
+A+G + ++ + V + S V H+ ++ S+ WSPH+ L+S
Sbjct: 371 LATGGGTSDRHIR-IWNVCSGACLSAV---------DAHS-QVCSILWSPHYK-ELISG- 417
Query: 660 YDGTAQ----VWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQ 715
G AQ +W + +GH R+L + SP D + S A D + W
Sbjct: 418 -HGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP-DGATVASAAADETLRLWRCFEL 475
Query: 716 DHSRPPQGKKSIELEKKRLSQ 736
D +R + +K+ + + Q
Sbjct: 476 DPARRREREKASAAKSSLIHQ 496
Score = 33.1 bits (74), Expect = 2.1
Identities = 44/197 (22%), Positives = 73/197 (37%), Gaps = 44/197 (22%)
Query: 76 PGQY----------NLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLI 125
PG+Y N A + V++WDV+ + + H + +L W+ + +
Sbjct: 225 PGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYI---L 281
Query: 126 VSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGY-KDGIVVIIDISKK 184
SG G + H + T S H +++ + + DG
Sbjct: 282 SSGSRSGHI----------HHHDVRVAEHHVATLSGHSQEVCGLRWAPDG---------- 321
Query: 185 GEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCYLAT 244
H G +D + ++ W PGE Q T + + AVA P + LAT
Sbjct: 322 ---RHLASGGNDNLVNV-WPSAPGEGGWVPLQTFTQHQGAV---KAVAWCP-WQSNVLAT 373
Query: 245 --GSKDQTIRIWSCSRG 259
G+ D+ IRIW+ G
Sbjct: 374 GGGTSDRHIRIWNVCSG 390
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 69.3 bits (168), Expect = 3e-11
Identities = 103/419 (24%), Positives = 166/419 (39%), Gaps = 63/419 (15%)
Query: 319 RKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSL 378
R T ++S EG HS V ++ T + L S S D V+ WD++T +T
Sbjct: 101 RAVTRCTSSLEG--HSEAVISVAFSPTG---KYLASGSGDTTVRFWDLSTETPHFTCKGH 155
Query: 379 GGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTK 438
+ S+++S D LA G +G I +W+ + K V G +T L W P
Sbjct: 156 RHWVLSISWSP-DGRKLASGCKNGQILLWDPSTGKQ---VGRTLAGHSKWITGLSWEPLH 211
Query: 439 EG----CLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRP 494
+A + DG V ++DT + + +I T H ++V L WG G+G
Sbjct: 212 ANPECRYVASSSKDGSVRIWDTTAGRCERIL-TGHTQSVTCLRWG---------GDG--- 258
Query: 495 SLALYSCGGEGIVLQHNPWK---------LSGEAFDINKLIRDTNSIKYKLPVHTEISWK 545
LYS + + W+ L G +N + T+ + T
Sbjct: 259 --LLYSASQDRTI---KVWRAHDGVLCRTLQGHGHWVNTMALSTD-----YALRTGAFEP 308
Query: 546 ADGKIMALGNEDGSIEIFQIPNLKLICTI--QQHHKLVN------TISWHHEHGSQPELS 597
A+ + + GS++ + L + Q +LV+ W +P
Sbjct: 309 AEASVNPQDLQ-GSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTR 367
Query: 598 YLMASGSNNAVIYVHNLKTVIESSPESPVTI----TEPY-RTLSGHTAKITSVAWSPHHD 652
N V++ + + V +S + + + T Y +L GH A + +AWS D
Sbjct: 368 MTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSA--D 425
Query: 653 GRL-VSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKW 710
RL VS S D T +VWD ++ + GH + V WSP D + SG D C+ W
Sbjct: 426 SRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSP-DGQRVASGGKDKCLRIW 483
Score = 65.9 bits (159), Expect = 3e-10
Identities = 102/426 (23%), Positives = 162/426 (38%), Gaps = 86/426 (20%)
Query: 55 RVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTIST 114
R L GH+E V FS G+Y A+ S D TV+ WD+ T+T H+H + +
Sbjct: 105 RCTSSLEGHSEAVISVAFSP-TGKY--LASGSGDTTVRFWDLSTETPHFTCKGHRHWVLS 161
Query: 115 LHWSPRVKDLIVSGDEKGVVFCY--WFNRNDSQHLFIEPRTIFCLTCSPHHED----LVA 168
+ WSP + L SG + G + + + + L + I L+ P H + VA
Sbjct: 162 ISWSPDGRKL-ASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVA 220
Query: 169 IGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNG 228
KDG V I D + G L GH + + W G D L
Sbjct: 221 SSSKDGSVRIWD-TTAGRCERILTGHTQSVTCLRW----GGDGL---------------- 259
Query: 229 NAVAQAPVTKGCYLATGSKDQTIRIWSCS--------RGRG----VMILKLPFLKRRG-- 274
L + S+D+TI++W +G G M L + R G
Sbjct: 260 -------------LYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAF 306
Query: 275 ----GGIDP--------TVKERLWLTLHWPSNQ-PTQLVSSCFGGELLQWDLTQSWRRKY 321
++P +KER + Q P +LVS L W + K
Sbjct: 307 EPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAED---KK 363
Query: 322 TLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGF 381
L + ++++F+ D +++ S S D+ +K WD T + +L
Sbjct: 364 PLTRMTGHQALINQVLFS-------PDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAA 416
Query: 382 AYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGC 441
Y +A+S+ D L G D ++VW+ + K D+ G +V A+ W P +
Sbjct: 417 VYQIAWSA-DSRLLVSGSSDSTLKVWDVKAQKLAMDL----PGHADEVYAVDWSPDGQRV 471
Query: 442 LAFGTD 447
+ G D
Sbjct: 472 ASGGKD 477
Score = 60.1 bits (144), Expect = 2e-08
Identities = 46/195 (23%), Positives = 81/195 (41%), Gaps = 24/195 (12%)
Query: 520 FDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHK 579
F + + R T+S++ +++ GK +A G+ D ++ + + T + H
Sbjct: 98 FRVRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRH 157
Query: 580 LVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHT 639
V +ISW + +ASG N I + + P T + RTL+GH+
Sbjct: 158 WVLSISWSPDGRK-------LASGCKNGQILLWD-----------PSTGKQVGRTLAGHS 199
Query: 640 AKITSVAWSPHHDG----RLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDP 695
IT ++W P H + S+S DG+ ++WD GH + C+ W
Sbjct: 200 KWITGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWG--GD 257
Query: 696 DCIYSGADDFCVHKW 710
+YS + D + W
Sbjct: 258 GLLYSASQDRTIKVW 272
Score = 35.8 bits (81), Expect = 0.32
Identities = 19/77 (24%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Query: 55 RVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTIST 114
+ + L GH V +S L + S D T+K+WDV+ + + + H +
Sbjct: 405 KYLASLRGHVAAVYQIAWS---ADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYA 461
Query: 115 LHWSPRVKDLIVSGDEK 131
+ WSP + + G +K
Sbjct: 462 VDWSPDGQRVASGGKDK 478
>gi|21536485 HIR histone cell cycle regulation defective homolog A
[Homo sapiens]
Length = 1017
Score = 65.5 bits (158), Expect = 4e-10
Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 17/152 (11%)
Query: 569 KLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSP----ES 624
K++C + H VN + W + +ASG ++ +I V T I S
Sbjct: 61 KMLCQMDNHLACVNCVRWSNS-------GMYLASGGDDKLIMVWKRATYIGPSTVFGSSG 113
Query: 625 PVTITEPYRTLS---GHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALR-EEPLCNFRG 680
+ E +R +S H+ + VAWSPH D L S S D T +W+A++ E L RG
Sbjct: 114 KLANVEQWRCVSILRNHSGDVMDVAWSPH-DAWLASCSVDNTVVIWNAVKFPEILATLRG 172
Query: 681 HRGRLLCVAWSPLDPDCIYSGADDFCVHKWLT 712
H G + + W P+ I S ADD + W T
Sbjct: 173 HSGLVKGLTWDPVG-KYIASQADDRSLKVWRT 203
Score = 31.6 bits (70), Expect = 6.1
Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 18/110 (16%)
Query: 603 GSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWS-------PHHDGRL 655
G ++ + + N+ V++ E I + + H A + V WS D +L
Sbjct: 34 GQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKL 93
Query: 656 V----SASYDGTAQVWD-----ALREEPLC--NFRGHRGRLLCVAWSPLD 694
+ A+Y G + V+ A E+ C R H G ++ VAWSP D
Sbjct: 94 IMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRNHSGDVMDVAWSPHD 143
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 64.3 bits (155), Expect = 8e-10
Identities = 82/343 (23%), Positives = 131/343 (38%), Gaps = 80/343 (23%)
Query: 395 LAIGVGDGMIRVWN--------TLSIKNNYDVKNFWQGVKSK--VTALCWHPTKEGCL-A 443
LA G GD R+WN + + + ++ Q V S VT+L W+ EG L A
Sbjct: 184 LASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWN--SEGTLLA 241
Query: 444 FGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGG 503
G+ DG ++ N + HK ++ L W ++ + S G
Sbjct: 242 TGSYDGFARIWTKDGNLASTLGQ--HKGPIFALKW-------------NKKGNFILSAG- 285
Query: 504 EGIVLQHNPWKLSGEAFDINKLIRD--TNSIKYKLPVHT----EISWKADGKIMALGNED 557
D +I D T K + P H+ ++ W+++ + D
Sbjct: 286 ----------------VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCST-D 328
Query: 558 GSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTV 617
I + ++ + I T Q H VN I W L+AS S++ + + ++K
Sbjct: 329 MCIHVCKLGQDRPIKTFQGHTNEVNAIKWD-------PTGNLLASCSDDMTLKIWSMKQ- 380
Query: 618 IESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGR--------LVSASYDGTAQVWDA 669
L H +I ++ WSP G L SAS+D T ++WD
Sbjct: 381 -----------DNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDV 429
Query: 670 LREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLT 712
R + H+ + VA+SP D + SG+ D CVH W T
Sbjct: 430 DRGICIHTLTKHQEPVYSVAFSP-DGRYLASGSFDKCVHIWNT 471
Score = 60.1 bits (144), Expect = 2e-08
Identities = 97/408 (23%), Positives = 160/408 (39%), Gaps = 80/408 (19%)
Query: 158 TCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQE 217
T + +H D++ + DG V +I V+ LRGH+ E+ AW P+
Sbjct: 140 TIANNHTDMMEV---DGDV---EIPPNKAVV--LRGHESEVFICAWNPVSD--------- 182
Query: 218 ETSEEAEITNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRG--RGVMILKLPFLKRRGG 275
LA+GS D T RIW+ S G L L R GG
Sbjct: 183 -----------------------LLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGG 219
Query: 276 GIDPTVKERLWLTLHWPSNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSASSEGQNHSR 335
P+ K+ +L W +++ T L + + G + W + L AS+ GQ+
Sbjct: 220 QDVPSNKD--VTSLDW-NSEGTLLATGSYDG------FARIWTKDGNL--ASTLGQHKGP 268
Query: 336 IVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSL 395
I L+ +LS +D+ WD T E P A + + S + +
Sbjct: 269 IF----ALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNN--TF 322
Query: 396 AIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYD 455
A D I V + + +K F QG ++V A+ W PT LA +DD + ++
Sbjct: 323 ASCSTDMCIHV---CKLGQDRPIKTF-QGHTNEVNAIKWDPT-GNLLASCSDDMTLKIWS 377
Query: 456 TYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKL 515
+ H K +YT+ W P P G +L L S + V
Sbjct: 378 MKQDNCVH-DLQAHNKEIYTIKWSPTGP----GTNNPNANLMLASASFDSTV-------- 424
Query: 516 SGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIF 563
+D+++ I K++ PV++ +++ DG+ +A G+ D + I+
Sbjct: 425 --RLWDVDRGICIHTLTKHQEPVYS-VAFSPDGRYLASGSFDKCVHIW 469
Score = 45.8 bits (107), Expect = 3e-04
Identities = 47/205 (22%), Positives = 71/205 (34%), Gaps = 70/205 (34%)
Query: 55 RVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTIST 114
R I GHT V+ + NL A+ SDD T+KIW ++ V + H I T
Sbjct: 340 RPIKTFQGHTNEVNAIKWDPTG---NLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYT 396
Query: 115 LHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDG 174
+ WSP T +P+ ++A D
Sbjct: 397 IKWSPTGPG----------------------------------TNNPNANLMLASASFDS 422
Query: 175 IVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQA 234
V + D+ +G IH L H + ++S+A+ P
Sbjct: 423 TVRLWDVD-RGICIHTLTKHQEPVYSVAFSP----------------------------- 452
Query: 235 PVTKGCYLATGSKDQTIRIWSCSRG 259
G YLA+GS D+ + IW+ G
Sbjct: 453 ---DGRYLASGSFDKCVHIWNTQTG 474
Score = 38.5 bits (88), Expect = 0.050
Identities = 66/257 (25%), Positives = 98/257 (38%), Gaps = 37/257 (14%)
Query: 166 LVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEI 225
L+A G DG I +K G + L H I ++ W G LS ++T+ +
Sbjct: 239 LLATGSYDGFARIW--TKDGNLASTLGQHKGPIFALKWNK-KGNFILSAGVDKTTIIWDA 295
Query: 226 TNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERL 285
G A Q P L + SCS + + KL G D +K
Sbjct: 296 HTGEAKQQFPFHSAPALDVDWQSNNT-FASCSTDMCIHVCKL--------GQDRPIKTFQ 346
Query: 286 WLT-----LHWPSNQPT-QLVSSCFGGELLQ-WDLTQSWRRKYTLFSASSEGQNHSRIVF 338
T + W PT L++SC L+ W + Q + + Q H++ ++
Sbjct: 347 GHTNEVNAIKW---DPTGNLLASCSDDMTLKIWSMKQD--------NCVHDLQAHNKEIY 395
Query: 339 NLC-----PLQTEDDKQLLL-STSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDI 392
+ P + L+L S S D V+ WD+ C TL YS+AFS D
Sbjct: 396 TIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSP-DG 454
Query: 393 GSLAIGVGDGMIRVWNT 409
LA G D + +WNT
Sbjct: 455 RYLASGSFDKCVHIWNT 471
Score = 35.0 bits (79), Expect = 0.55
Identities = 37/153 (24%), Positives = 67/153 (43%), Gaps = 23/153 (15%)
Query: 557 DGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKT 616
DG +EI PN ++ ++ H V +W+ +S L+ASGS ++ + NL
Sbjct: 152 DGDVEI--PPNKAVV--LRGHESEVFICAWN-------PVSDLLASGSGDSTARIWNLS- 199
Query: 617 VIESSPESPVTITEPYRTLSG-----HTAKITSVAWSPHHDGRLVSASYDGTAQVWDALR 671
E+S + + G +TS+ W+ L + SYDG A++W +
Sbjct: 200 --ENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGT-LLATGSYDGFARIW--TK 254
Query: 672 EEPLCNFRG-HRGRLLCVAWSPLDPDCIYSGAD 703
+ L + G H+G + + W+ + +G D
Sbjct: 255 DGNLASTLGQHKGPIFALKWNKKGNFILSAGVD 287
Score = 33.9 bits (76), Expect = 1.2
Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 2/111 (1%)
Query: 73 SHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKG 132
+++P + A++S D TV++WDV+ + HQ + ++ +SP + + SG
Sbjct: 406 TNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGR-YLASGSFDK 464
Query: 133 VVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISK 183
V + H + IF C D V DG V ++D+ K
Sbjct: 465 CVHIWNTQTGALVHSYRGTGGIF-EVCWNAAGDKVGASASDGSVCVLDLRK 514
>gi|209969680 Fzr1 protein isoform 1 [Homo sapiens]
Length = 496
Score = 63.5 bits (153), Expect = 1e-09
Identities = 43/175 (24%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 540 TEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYL 599
T + W G ++A+G G ++I+ K + ++ H V ++W+ E
Sbjct: 233 TSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--------- 283
Query: 600 MASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSAS 659
++SGS + +I +++T P +E R L GH ++ + WS H L S
Sbjct: 284 LSSGSRDRMILQRDIRT--------PPLQSE--RRLQGHRQEVCGLKWSTDHQ-LLASGG 332
Query: 660 YDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGAD--DFCVHKWLT 712
D VW+ P+ + H + +AWSP + SG D C+ W T
Sbjct: 333 NDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNT 387
Score = 47.4 bits (111), Expect = 1e-04
Identities = 47/208 (22%), Positives = 82/208 (39%), Gaps = 39/208 (18%)
Query: 51 TPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQH 110
TPP + L GH + V G +S + L A+ +D + +W+ + + V ++ H
Sbjct: 300 TPPLQSERRLQGHRQEVCGLKWST---DHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLA 356
Query: 111 TISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHL-FIEPRTIFC-LTCSPHHEDLVA 168
+ + WSP L+ SG ++N Q L I+ + C L S H +LV+
Sbjct: 357 AVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVS 416
Query: 169 I-GYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITN 227
GY +++ +V +L GH + +A P +
Sbjct: 417 THGYSQNQILVWKYPSLTQVA-KLTGHSYRVLYLAMSP---------------------D 454
Query: 228 GNAVAQAPVTKGCYLATGSKDQTIRIWS 255
G A+ TG+ D+T+R W+
Sbjct: 455 GEAI-----------VTGAGDETLRFWN 471
Score = 33.9 bits (76), Expect = 1.2
Identities = 47/180 (26%), Positives = 69/180 (38%), Gaps = 36/180 (20%)
Query: 238 KGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPT 297
+G +A G+ ++IW + G+ + +L+ G V W
Sbjct: 240 RGNLVAVGTHKGFVQIWDAAAGKKLSMLE---------GHTARVGALAW--------NAE 282
Query: 298 QLVSSCFGGELLQWDLT----QSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLL 353
QL S +LQ D+ QS RR Q H + V C L+ D QLL
Sbjct: 283 QLSSGSRDRMILQRDIRTPPLQSERRL----------QGHRQEV---CGLKWSTDHQLLA 329
Query: 354 STSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVG--DGMIRVWNTLS 411
S D + W+ ++L ++A+S G LA G G D IR WNTL+
Sbjct: 330 SGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLT 389
>gi|209969678 Fzr1 protein isoform 3 [Homo sapiens]
Length = 404
Score = 63.5 bits (153), Expect = 1e-09
Identities = 43/175 (24%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 540 TEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYL 599
T + W G ++A+G G ++I+ K + ++ H V ++W+ E
Sbjct: 144 TSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--------- 194
Query: 600 MASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSAS 659
++SGS + +I +++T P +E R L GH ++ + WS H L S
Sbjct: 195 LSSGSRDRMILQRDIRT--------PPLQSE--RRLQGHRQEVCGLKWSTDHQ-LLASGG 243
Query: 660 YDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGAD--DFCVHKWLT 712
D VW+ P+ + H + +AWSP + SG D C+ W T
Sbjct: 244 NDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNT 298
Score = 47.4 bits (111), Expect = 1e-04
Identities = 47/208 (22%), Positives = 82/208 (39%), Gaps = 39/208 (18%)
Query: 51 TPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQH 110
TPP + L GH + V G +S + L A+ +D + +W+ + + V ++ H
Sbjct: 211 TPPLQSERRLQGHRQEVCGLKWST---DHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLA 267
Query: 111 TISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHL-FIEPRTIFC-LTCSPHHEDLVA 168
+ + WSP L+ SG ++N Q L I+ + C L S H +LV+
Sbjct: 268 AVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVS 327
Query: 169 I-GYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITN 227
GY +++ +V +L GH + +A P +
Sbjct: 328 THGYSQNQILVWKYPSLTQVA-KLTGHSYRVLYLAMSP---------------------D 365
Query: 228 GNAVAQAPVTKGCYLATGSKDQTIRIWS 255
G A+ TG+ D+T+R W+
Sbjct: 366 GEAI-----------VTGAGDETLRFWN 382
Score = 33.9 bits (76), Expect = 1.2
Identities = 47/180 (26%), Positives = 69/180 (38%), Gaps = 36/180 (20%)
Query: 238 KGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPT 297
+G +A G+ ++IW + G+ + +L+ G V W
Sbjct: 151 RGNLVAVGTHKGFVQIWDAAAGKKLSMLE---------GHTARVGALAW--------NAE 193
Query: 298 QLVSSCFGGELLQWDLT----QSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLL 353
QL S +LQ D+ QS RR Q H + V C L+ D QLL
Sbjct: 194 QLSSGSRDRMILQRDIRTPPLQSERRL----------QGHRQEV---CGLKWSTDHQLLA 240
Query: 354 STSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVG--DGMIRVWNTLS 411
S D + W+ ++L ++A+S G LA G G D IR WNTL+
Sbjct: 241 SGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLT 300
>gi|33620742 Fzr1 protein isoform 2 [Homo sapiens]
Length = 493
Score = 63.5 bits (153), Expect = 1e-09
Identities = 43/175 (24%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 540 TEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYL 599
T + W G ++A+G G ++I+ K + ++ H V ++W+ E
Sbjct: 233 TSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ--------- 283
Query: 600 MASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSAS 659
++SGS + +I +++T P +E R L GH ++ + WS H L S
Sbjct: 284 LSSGSRDRMILQRDIRT--------PPLQSE--RRLQGHRQEVCGLKWSTDHQ-LLASGG 332
Query: 660 YDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGAD--DFCVHKWLT 712
D VW+ P+ + H + +AWSP + SG D C+ W T
Sbjct: 333 NDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNT 387
Score = 47.4 bits (111), Expect = 1e-04
Identities = 47/208 (22%), Positives = 82/208 (39%), Gaps = 39/208 (18%)
Query: 51 TPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQH 110
TPP + L GH + V G +S + L A+ +D + +W+ + + V ++ H
Sbjct: 300 TPPLQSERRLQGHRQEVCGLKWST---DHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLA 356
Query: 111 TISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHL-FIEPRTIFC-LTCSPHHEDLVA 168
+ + WSP L+ SG ++N Q L I+ + C L S H +LV+
Sbjct: 357 AVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVS 416
Query: 169 I-GYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITN 227
GY +++ +V +L GH + +A P +
Sbjct: 417 THGYSQNQILVWKYPSLTQVA-KLTGHSYRVLYLAMSP---------------------D 454
Query: 228 GNAVAQAPVTKGCYLATGSKDQTIRIWS 255
G A+ TG+ D+T+R W+
Sbjct: 455 GEAI-----------VTGAGDETLRFWN 471
Score = 33.9 bits (76), Expect = 1.2
Identities = 47/180 (26%), Positives = 69/180 (38%), Gaps = 36/180 (20%)
Query: 238 KGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPT 297
+G +A G+ ++IW + G+ + +L+ G V W
Sbjct: 240 RGNLVAVGTHKGFVQIWDAAAGKKLSMLE---------GHTARVGALAW--------NAE 282
Query: 298 QLVSSCFGGELLQWDLT----QSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLL 353
QL S +LQ D+ QS RR Q H + V C L+ D QLL
Sbjct: 283 QLSSGSRDRMILQRDIRTPPLQSERRL----------QGHRQEV---CGLKWSTDHQLLA 329
Query: 354 STSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVG--DGMIRVWNTLS 411
S D + W+ ++L ++A+S G LA G G D IR WNTL+
Sbjct: 330 SGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLT 389
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 62.4 bits (150), Expect = 3e-09
Identities = 81/342 (23%), Positives = 129/342 (37%), Gaps = 78/342 (22%)
Query: 395 LAIGVGDGMIRVWNTLSIKNN--------YDVKNFWQGVKSK--VTALCWHPTKEGCLAF 444
LA G GD R+WN N + ++ V S VT+L W+ T LA
Sbjct: 196 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWN-TNGTLLAT 254
Query: 445 GTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGE 504
G+ DG ++ N + HK ++ L W +R + S G
Sbjct: 255 GSYDGFARIWTEDGNLASTLGQ--HKGPIFALKW-------------NRKGNYILSAG-- 297
Query: 505 GIVLQHNPWKLSGEAFDINKLIRD--TNSIKYKLPVHT----EISWKADGKIMALGNEDG 558
D +I D T K + P H+ ++ W+ + A + D
Sbjct: 298 ---------------VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNTTFASCSTDM 341
Query: 559 SIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVI 618
I + ++ + + T Q H VN I W L+AS S++ + + ++K +
Sbjct: 342 CIHVCRLGCDRPVKTFQGHTNEVNAIKWDPS-------GMLLASCSDDMTLKIWSMKQEV 394
Query: 619 ESSPESPVTITEPYRTLSGHTAKITSVAWSP--------HHDGRLVSASYDGTAQVWDAL 670
L H +I ++ WSP + + L SAS+D T ++WD
Sbjct: 395 ------------CIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIE 442
Query: 671 REEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLT 712
R H+ + VA+SP D + SG+ D CVH W T
Sbjct: 443 RGVCTHTLTKHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNT 483
Score = 51.2 bits (121), Expect = 7e-06
Identities = 89/383 (23%), Positives = 146/383 (38%), Gaps = 72/383 (18%)
Query: 191 LRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQT 250
LRGH+ E+ AW P+ LA+GS D T
Sbjct: 177 LRGHESEVFICAWNPVSD--------------------------------LLASGSGDST 204
Query: 251 IRIWSCSRGR--GVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGEL 308
RIW+ + G L L R GG P+ K+ +L W +N T L + + G
Sbjct: 205 ARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVT--SLDWNTNG-TLLATGSYDG-- 259
Query: 309 LQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIAT 368
+ W L AS+ GQ+ I L+ +LS +D+ WD T
Sbjct: 260 ----FARIWTEDGNL--ASTLGQHKGPIF----ALKWNRKGNYILSAGVDKTTIIWDAHT 309
Query: 369 LECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSK 428
E P A + + + + A D I V + + VK F QG ++
Sbjct: 310 GEAKQQFPFHSAPALDVDWQNNT--TFASCSTDMCIHVCR---LGCDRPVKTF-QGHTNE 363
Query: 429 VTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLG 488
V A+ W P+ LA +DD + ++ + + H K +YT+ W P P S
Sbjct: 364 VNAIKWDPSGM-LLASCSDDMTLKIW-SMKQEVCIHDLQAHNKEIYTIKWSPTGPATS-- 419
Query: 489 GEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADG 548
P+ I+L + + +DI + + K++ PV++ +++ DG
Sbjct: 420 ----NPN--------SNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYS-VAFSPDG 466
Query: 549 KIMALGNEDGSIEIFQIPNLKLI 571
K +A G+ D + I+ + L+
Sbjct: 467 KYLASGSFDKCVHIWNTQSGNLV 489
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/205 (21%), Positives = 71/205 (34%), Gaps = 70/205 (34%)
Query: 55 RVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTIST 114
R + GHT V+ + L A+ SDD T+KIW ++ + + + H I T
Sbjct: 352 RPVKTFQGHTNEVNAIKWDPSG---MLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYT 408
Query: 115 LHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDG 174
+ WSP T +P+ ++A D
Sbjct: 409 IKWSPTGP----------------------------------ATSNPNSNIMLASASFDS 434
Query: 175 IVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQA 234
V + DI ++G H L H + ++S+A+ P
Sbjct: 435 TVRLWDI-ERGVCTHTLTKHQEPVYSVAFSP----------------------------- 464
Query: 235 PVTKGCYLATGSKDQTIRIWSCSRG 259
G YLA+GS D+ + IW+ G
Sbjct: 465 ---DGKYLASGSFDKCVHIWNTQSG 486
Score = 43.1 bits (100), Expect = 0.002
Identities = 81/335 (24%), Positives = 124/335 (37%), Gaps = 60/335 (17%)
Query: 108 HQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRND---SQHLFIEPRTIFCLTCSPH-- 162
H+ + W+P V DL+ SG + N N S L + C+ H
Sbjct: 180 HESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLR----HCIREGGHDV 234
Query: 163 -------------HEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGE 209
+ L+A G DG I ++ G + L H I ++ W G
Sbjct: 235 PSNKDVTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKW-NRKGN 291
Query: 210 DCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPF 269
LS ++T+ + G A Q P L ++ T SCS + + +L
Sbjct: 292 YILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTT-FASCSTDMCIHVCRL-- 348
Query: 270 LKRRGGGIDPTVKERLWLT-----LHW-PSNQPTQLVSSCFGGELLQ-WDLTQSWRRKYT 322
G D VK T + W PS L++SC L+ W + Q
Sbjct: 349 ------GCDRPVKTFQGHTNEVNAIKWDPSGM---LLASCSDDMTLKIWSMKQE------ 393
Query: 323 LFSASSEGQNHSRIVFNLC-----PLQTEDDKQLLL-STSMDRDVKCWDIATLECSWTLP 376
+ Q H++ ++ + P + + ++L S S D V+ WDI C+ TL
Sbjct: 394 --VCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLT 451
Query: 377 SLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLS 411
YS+AFS D LA G D + +WNT S
Sbjct: 452 KHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNTQS 485
Score = 36.6 bits (83), Expect = 0.19
Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 2/109 (1%)
Query: 75 HPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVV 134
+P + A++S D TV++WD+E HQ + ++ +SP K + SG V
Sbjct: 420 NPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGK-YLASGSFDKCV 478
Query: 135 FCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISK 183
+ + H + IF C D V DG V ++D+ K
Sbjct: 479 HIWNTQSGNLVHSYRGTGGIF-EVCWNARGDKVGASASDGSVCVLDLRK 526
Score = 34.3 bits (77), Expect = 0.94
Identities = 38/152 (25%), Positives = 66/152 (43%), Gaps = 21/152 (13%)
Query: 557 DGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKT 616
DG +EI P+ K ++ H V +W+ +S L+ASGS ++ + NL
Sbjct: 164 DGEVEI---PSSKAT-VLRGHESEVFICAWN-------PVSDLLASGSGDSTARIWNLNE 212
Query: 617 VIESSPESPVTITEPYRTLSGHTAK----ITSVAWSPHHDGRLVSASYDGTAQVWDALRE 672
S+ S + GH +TS+ W+ + L + SYDG A++W +
Sbjct: 213 --NSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGT-LLATGSYDGFARIW--TED 267
Query: 673 EPLCNFRG-HRGRLLCVAWSPLDPDCIYSGAD 703
L + G H+G + + W+ + +G D
Sbjct: 268 GNLASTLGQHKGPIFALKWNRKGNYILSAGVD 299
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 62.4 bits (150), Expect = 3e-09
Identities = 81/342 (23%), Positives = 129/342 (37%), Gaps = 78/342 (22%)
Query: 395 LAIGVGDGMIRVWNTLSIKNN--------YDVKNFWQGVKSK--VTALCWHPTKEGCLAF 444
LA G GD R+WN N + ++ V S VT+L W+ T LA
Sbjct: 196 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWN-TNGTLLAT 254
Query: 445 GTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGE 504
G+ DG ++ N + HK ++ L W +R + S G
Sbjct: 255 GSYDGFARIWTEDGNLASTLGQ--HKGPIFALKW-------------NRKGNYILSAG-- 297
Query: 505 GIVLQHNPWKLSGEAFDINKLIRD--TNSIKYKLPVHT----EISWKADGKIMALGNEDG 558
D +I D T K + P H+ ++ W+ + A + D
Sbjct: 298 ---------------VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNTTFASCSTDM 341
Query: 559 SIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVI 618
I + ++ + + T Q H VN I W L+AS S++ + + ++K +
Sbjct: 342 CIHVCRLGCDRPVKTFQGHTNEVNAIKWDPS-------GMLLASCSDDMTLKIWSMKQEV 394
Query: 619 ESSPESPVTITEPYRTLSGHTAKITSVAWSP--------HHDGRLVSASYDGTAQVWDAL 670
L H +I ++ WSP + + L SAS+D T ++WD
Sbjct: 395 ------------CIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIE 442
Query: 671 REEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLT 712
R H+ + VA+SP D + SG+ D CVH W T
Sbjct: 443 RGVCTHTLTKHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNT 483
Score = 51.2 bits (121), Expect = 7e-06
Identities = 89/383 (23%), Positives = 146/383 (38%), Gaps = 72/383 (18%)
Query: 191 LRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQT 250
LRGH+ E+ AW P+ LA+GS D T
Sbjct: 177 LRGHESEVFICAWNPVSD--------------------------------LLASGSGDST 204
Query: 251 IRIWSCSRGR--GVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGEL 308
RIW+ + G L L R GG P+ K+ +L W +N T L + + G
Sbjct: 205 ARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVT--SLDWNTNG-TLLATGSYDG-- 259
Query: 309 LQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIAT 368
+ W L AS+ GQ+ I L+ +LS +D+ WD T
Sbjct: 260 ----FARIWTEDGNL--ASTLGQHKGPIF----ALKWNRKGNYILSAGVDKTTIIWDAHT 309
Query: 369 LECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSK 428
E P A + + + + A D I V + + VK F QG ++
Sbjct: 310 GEAKQQFPFHSAPALDVDWQNNT--TFASCSTDMCIHVCR---LGCDRPVKTF-QGHTNE 363
Query: 429 VTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLG 488
V A+ W P+ LA +DD + ++ + + H K +YT+ W P P S
Sbjct: 364 VNAIKWDPSGM-LLASCSDDMTLKIW-SMKQEVCIHDLQAHNKEIYTIKWSPTGPATS-- 419
Query: 489 GEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADG 548
P+ I+L + + +DI + + K++ PV++ +++ DG
Sbjct: 420 ----NPN--------SNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYS-VAFSPDG 466
Query: 549 KIMALGNEDGSIEIFQIPNLKLI 571
K +A G+ D + I+ + L+
Sbjct: 467 KYLASGSFDKCVHIWNTQSGNLV 489
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/205 (21%), Positives = 71/205 (34%), Gaps = 70/205 (34%)
Query: 55 RVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTIST 114
R + GHT V+ + L A+ SDD T+KIW ++ + + + H I T
Sbjct: 352 RPVKTFQGHTNEVNAIKWDPSG---MLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYT 408
Query: 115 LHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDG 174
+ WSP T +P+ ++A D
Sbjct: 409 IKWSPTGP----------------------------------ATSNPNSNIMLASASFDS 434
Query: 175 IVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQA 234
V + DI ++G H L H + ++S+A+ P
Sbjct: 435 TVRLWDI-ERGVCTHTLTKHQEPVYSVAFSP----------------------------- 464
Query: 235 PVTKGCYLATGSKDQTIRIWSCSRG 259
G YLA+GS D+ + IW+ G
Sbjct: 465 ---DGKYLASGSFDKCVHIWNTQSG 486
Score = 43.1 bits (100), Expect = 0.002
Identities = 81/335 (24%), Positives = 124/335 (37%), Gaps = 60/335 (17%)
Query: 108 HQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRND---SQHLFIEPRTIFCLTCSPH-- 162
H+ + W+P V DL+ SG + N N S L + C+ H
Sbjct: 180 HESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLR----HCIREGGHDV 234
Query: 163 -------------HEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGE 209
+ L+A G DG I ++ G + L H I ++ W G
Sbjct: 235 PSNKDVTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKW-NRKGN 291
Query: 210 DCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPF 269
LS ++T+ + G A Q P L ++ T SCS + + +L
Sbjct: 292 YILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTT-FASCSTDMCIHVCRL-- 348
Query: 270 LKRRGGGIDPTVKERLWLT-----LHW-PSNQPTQLVSSCFGGELLQ-WDLTQSWRRKYT 322
G D VK T + W PS L++SC L+ W + Q
Sbjct: 349 ------GCDRPVKTFQGHTNEVNAIKWDPSGM---LLASCSDDMTLKIWSMKQE------ 393
Query: 323 LFSASSEGQNHSRIVFNLC-----PLQTEDDKQLLL-STSMDRDVKCWDIATLECSWTLP 376
+ Q H++ ++ + P + + ++L S S D V+ WDI C+ TL
Sbjct: 394 --VCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLT 451
Query: 377 SLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLS 411
YS+AFS D LA G D + +WNT S
Sbjct: 452 KHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNTQS 485
Score = 36.6 bits (83), Expect = 0.19
Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 2/109 (1%)
Query: 75 HPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVV 134
+P + A++S D TV++WD+E HQ + ++ +SP K + SG V
Sbjct: 420 NPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGK-YLASGSFDKCV 478
Query: 135 FCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISK 183
+ + H + IF C D V DG V ++D+ K
Sbjct: 479 HIWNTQSGNLVHSYRGTGGIF-EVCWNARGDKVGASASDGSVCVLDLRK 526
Score = 34.3 bits (77), Expect = 0.94
Identities = 38/152 (25%), Positives = 66/152 (43%), Gaps = 21/152 (13%)
Query: 557 DGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKT 616
DG +EI P+ K ++ H V +W+ +S L+ASGS ++ + NL
Sbjct: 164 DGEVEI---PSSKAT-VLRGHESEVFICAWN-------PVSDLLASGSGDSTARIWNLNE 212
Query: 617 VIESSPESPVTITEPYRTLSGHTAK----ITSVAWSPHHDGRLVSASYDGTAQVWDALRE 672
S+ S + GH +TS+ W+ + L + SYDG A++W +
Sbjct: 213 --NSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGT-LLATGSYDGFARIW--TED 267
Query: 673 EPLCNFRG-HRGRLLCVAWSPLDPDCIYSGAD 703
L + G H+G + + W+ + +G D
Sbjct: 268 GNLASTLGQHKGPIFALKWNRKGNYILSAGVD 299
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 62.4 bits (150), Expect = 3e-09
Identities = 81/342 (23%), Positives = 129/342 (37%), Gaps = 78/342 (22%)
Query: 395 LAIGVGDGMIRVWNTLSIKNN--------YDVKNFWQGVKSK--VTALCWHPTKEGCLAF 444
LA G GD R+WN N + ++ V S VT+L W+ T LA
Sbjct: 247 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWN-TNGTLLAT 305
Query: 445 GTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGE 504
G+ DG ++ N + HK ++ L W +R + S G
Sbjct: 306 GSYDGFARIWTEDGNLASTLGQ--HKGPIFALKW-------------NRKGNYILSAG-- 348
Query: 505 GIVLQHNPWKLSGEAFDINKLIRD--TNSIKYKLPVHT----EISWKADGKIMALGNEDG 558
D +I D T K + P H+ ++ W+ + A + D
Sbjct: 349 ---------------VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNTTFASCSTDM 392
Query: 559 SIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVI 618
I + ++ + + T Q H VN I W L+AS S++ + + ++K +
Sbjct: 393 CIHVCRLGCDRPVKTFQGHTNEVNAIKWDPS-------GMLLASCSDDMTLKIWSMKQEV 445
Query: 619 ESSPESPVTITEPYRTLSGHTAKITSVAWSP--------HHDGRLVSASYDGTAQVWDAL 670
L H +I ++ WSP + + L SAS+D T ++WD
Sbjct: 446 ------------CIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIE 493
Query: 671 REEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLT 712
R H+ + VA+SP D + SG+ D CVH W T
Sbjct: 494 RGVCTHTLTKHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNT 534
Score = 51.2 bits (121), Expect = 7e-06
Identities = 89/383 (23%), Positives = 146/383 (38%), Gaps = 72/383 (18%)
Query: 191 LRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQT 250
LRGH+ E+ AW P+ LA+GS D T
Sbjct: 228 LRGHESEVFICAWNPVSD--------------------------------LLASGSGDST 255
Query: 251 IRIWSCSRGR--GVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGEL 308
RIW+ + G L L R GG P+ K+ +L W +N T L + + G
Sbjct: 256 ARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVT--SLDWNTNG-TLLATGSYDG-- 310
Query: 309 LQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIAT 368
+ W L AS+ GQ+ I L+ +LS +D+ WD T
Sbjct: 311 ----FARIWTEDGNL--ASTLGQHKGPIF----ALKWNRKGNYILSAGVDKTTIIWDAHT 360
Query: 369 LECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSK 428
E P A + + + + A D I V + + VK F QG ++
Sbjct: 361 GEAKQQFPFHSAPALDVDWQNNT--TFASCSTDMCIHVCR---LGCDRPVKTF-QGHTNE 414
Query: 429 VTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLG 488
V A+ W P+ LA +DD + ++ + + H K +YT+ W P P S
Sbjct: 415 VNAIKWDPSGM-LLASCSDDMTLKIW-SMKQEVCIHDLQAHNKEIYTIKWSPTGPATS-- 470
Query: 489 GEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADG 548
P+ I+L + + +DI + + K++ PV++ +++ DG
Sbjct: 471 ----NPN--------SNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYS-VAFSPDG 517
Query: 549 KIMALGNEDGSIEIFQIPNLKLI 571
K +A G+ D + I+ + L+
Sbjct: 518 KYLASGSFDKCVHIWNTQSGNLV 540
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/205 (21%), Positives = 71/205 (34%), Gaps = 70/205 (34%)
Query: 55 RVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTIST 114
R + GHT V+ + L A+ SDD T+KIW ++ + + + H I T
Sbjct: 403 RPVKTFQGHTNEVNAIKWDPSG---MLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYT 459
Query: 115 LHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDG 174
+ WSP T +P+ ++A D
Sbjct: 460 IKWSPTGP----------------------------------ATSNPNSNIMLASASFDS 485
Query: 175 IVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQA 234
V + DI ++G H L H + ++S+A+ P
Sbjct: 486 TVRLWDI-ERGVCTHTLTKHQEPVYSVAFSP----------------------------- 515
Query: 235 PVTKGCYLATGSKDQTIRIWSCSRG 259
G YLA+GS D+ + IW+ G
Sbjct: 516 ---DGKYLASGSFDKCVHIWNTQSG 537
Score = 43.1 bits (100), Expect = 0.002
Identities = 81/335 (24%), Positives = 124/335 (37%), Gaps = 60/335 (17%)
Query: 108 HQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRND---SQHLFIEPRTIFCLTCSPH-- 162
H+ + W+P V DL+ SG + N N S L + C+ H
Sbjct: 231 HESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLR----HCIREGGHDV 285
Query: 163 -------------HEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGE 209
+ L+A G DG I ++ G + L H I ++ W G
Sbjct: 286 PSNKDVTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKW-NRKGN 342
Query: 210 DCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPF 269
LS ++T+ + G A Q P L ++ T SCS + + +L
Sbjct: 343 YILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTT-FASCSTDMCIHVCRL-- 399
Query: 270 LKRRGGGIDPTVKERLWLT-----LHW-PSNQPTQLVSSCFGGELLQ-WDLTQSWRRKYT 322
G D VK T + W PS L++SC L+ W + Q
Sbjct: 400 ------GCDRPVKTFQGHTNEVNAIKWDPSGM---LLASCSDDMTLKIWSMKQE------ 444
Query: 323 LFSASSEGQNHSRIVFNLC-----PLQTEDDKQLLL-STSMDRDVKCWDIATLECSWTLP 376
+ Q H++ ++ + P + + ++L S S D V+ WDI C+ TL
Sbjct: 445 --VCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLT 502
Query: 377 SLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLS 411
YS+AFS D LA G D + +WNT S
Sbjct: 503 KHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNTQS 536
Score = 36.6 bits (83), Expect = 0.19
Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 2/109 (1%)
Query: 75 HPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVV 134
+P + A++S D TV++WD+E HQ + ++ +SP K + SG V
Sbjct: 471 NPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGK-YLASGSFDKCV 529
Query: 135 FCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISK 183
+ + H + IF C D V DG V ++D+ K
Sbjct: 530 HIWNTQSGNLVHSYRGTGGIF-EVCWNARGDKVGASASDGSVCVLDLRK 577
Score = 34.3 bits (77), Expect = 0.94
Identities = 38/152 (25%), Positives = 66/152 (43%), Gaps = 21/152 (13%)
Query: 557 DGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKT 616
DG +EI P+ K ++ H V +W+ +S L+ASGS ++ + NL
Sbjct: 215 DGEVEI---PSSKAT-VLRGHESEVFICAWN-------PVSDLLASGSGDSTARIWNLNE 263
Query: 617 VIESSPESPVTITEPYRTLSGHTAK----ITSVAWSPHHDGRLVSASYDGTAQVWDALRE 672
S+ S + GH +TS+ W+ + L + SYDG A++W +
Sbjct: 264 --NSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGT-LLATGSYDGFARIW--TED 318
Query: 673 EPLCNFRG-HRGRLLCVAWSPLDPDCIYSGAD 703
L + G H+G + + W+ + +G D
Sbjct: 319 GNLASTLGQHKGPIFALKWNRKGNYILSAGVD 350
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 62.4 bits (150), Expect = 3e-09
Identities = 81/342 (23%), Positives = 129/342 (37%), Gaps = 78/342 (22%)
Query: 395 LAIGVGDGMIRVWNTLSIKNN--------YDVKNFWQGVKSK--VTALCWHPTKEGCLAF 444
LA G GD R+WN N + ++ V S VT+L W+ T LA
Sbjct: 247 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWN-TNGTLLAT 305
Query: 445 GTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGE 504
G+ DG ++ N + HK ++ L W +R + S G
Sbjct: 306 GSYDGFARIWTEDGNLASTLGQ--HKGPIFALKW-------------NRKGNYILSAG-- 348
Query: 505 GIVLQHNPWKLSGEAFDINKLIRD--TNSIKYKLPVHT----EISWKADGKIMALGNEDG 558
D +I D T K + P H+ ++ W+ + A + D
Sbjct: 349 ---------------VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNTTFASCSTDM 392
Query: 559 SIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVI 618
I + ++ + + T Q H VN I W L+AS S++ + + ++K +
Sbjct: 393 CIHVCRLGCDRPVKTFQGHTNEVNAIKWDPS-------GMLLASCSDDMTLKIWSMKQEV 445
Query: 619 ESSPESPVTITEPYRTLSGHTAKITSVAWSP--------HHDGRLVSASYDGTAQVWDAL 670
L H +I ++ WSP + + L SAS+D T ++WD
Sbjct: 446 ------------CIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIE 493
Query: 671 REEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLT 712
R H+ + VA+SP D + SG+ D CVH W T
Sbjct: 494 RGVCTHTLTKHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNT 534
Score = 51.2 bits (121), Expect = 7e-06
Identities = 89/383 (23%), Positives = 146/383 (38%), Gaps = 72/383 (18%)
Query: 191 LRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQT 250
LRGH+ E+ AW P+ LA+GS D T
Sbjct: 228 LRGHESEVFICAWNPVSD--------------------------------LLASGSGDST 255
Query: 251 IRIWSCSRGR--GVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGEL 308
RIW+ + G L L R GG P+ K+ +L W +N T L + + G
Sbjct: 256 ARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVT--SLDWNTNG-TLLATGSYDG-- 310
Query: 309 LQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIAT 368
+ W L AS+ GQ+ I L+ +LS +D+ WD T
Sbjct: 311 ----FARIWTEDGNL--ASTLGQHKGPIF----ALKWNRKGNYILSAGVDKTTIIWDAHT 360
Query: 369 LECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSK 428
E P A + + + + A D I V + + VK F QG ++
Sbjct: 361 GEAKQQFPFHSAPALDVDWQNNT--TFASCSTDMCIHVCR---LGCDRPVKTF-QGHTNE 414
Query: 429 VTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLG 488
V A+ W P+ LA +DD + ++ + + H K +YT+ W P P S
Sbjct: 415 VNAIKWDPSGM-LLASCSDDMTLKIW-SMKQEVCIHDLQAHNKEIYTIKWSPTGPATS-- 470
Query: 489 GEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADG 548
P+ I+L + + +DI + + K++ PV++ +++ DG
Sbjct: 471 ----NPN--------SNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYS-VAFSPDG 517
Query: 549 KIMALGNEDGSIEIFQIPNLKLI 571
K +A G+ D + I+ + L+
Sbjct: 518 KYLASGSFDKCVHIWNTQSGNLV 540
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/205 (21%), Positives = 71/205 (34%), Gaps = 70/205 (34%)
Query: 55 RVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTIST 114
R + GHT V+ + L A+ SDD T+KIW ++ + + + H I T
Sbjct: 403 RPVKTFQGHTNEVNAIKWDPSG---MLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYT 459
Query: 115 LHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDG 174
+ WSP T +P+ ++A D
Sbjct: 460 IKWSPTGP----------------------------------ATSNPNSNIMLASASFDS 485
Query: 175 IVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQA 234
V + DI ++G H L H + ++S+A+ P
Sbjct: 486 TVRLWDI-ERGVCTHTLTKHQEPVYSVAFSP----------------------------- 515
Query: 235 PVTKGCYLATGSKDQTIRIWSCSRG 259
G YLA+GS D+ + IW+ G
Sbjct: 516 ---DGKYLASGSFDKCVHIWNTQSG 537
Score = 43.1 bits (100), Expect = 0.002
Identities = 81/335 (24%), Positives = 124/335 (37%), Gaps = 60/335 (17%)
Query: 108 HQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRND---SQHLFIEPRTIFCLTCSPH-- 162
H+ + W+P V DL+ SG + N N S L + C+ H
Sbjct: 231 HESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLR----HCIREGGHDV 285
Query: 163 -------------HEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGE 209
+ L+A G DG I ++ G + L H I ++ W G
Sbjct: 286 PSNKDVTSLDWNTNGTLLATGSYDGFARIW--TEDGNLASTLGQHKGPIFALKW-NRKGN 342
Query: 210 DCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPF 269
LS ++T+ + G A Q P L ++ T SCS + + +L
Sbjct: 343 YILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTT-FASCSTDMCIHVCRL-- 399
Query: 270 LKRRGGGIDPTVKERLWLT-----LHW-PSNQPTQLVSSCFGGELLQ-WDLTQSWRRKYT 322
G D VK T + W PS L++SC L+ W + Q
Sbjct: 400 ------GCDRPVKTFQGHTNEVNAIKWDPSGM---LLASCSDDMTLKIWSMKQE------ 444
Query: 323 LFSASSEGQNHSRIVFNLC-----PLQTEDDKQLLL-STSMDRDVKCWDIATLECSWTLP 376
+ Q H++ ++ + P + + ++L S S D V+ WDI C+ TL
Sbjct: 445 --VCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLT 502
Query: 377 SLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLS 411
YS+AFS D LA G D + +WNT S
Sbjct: 503 KHQEPVYSVAFSP-DGKYLASGSFDKCVHIWNTQS 536
Score = 36.6 bits (83), Expect = 0.19
Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 2/109 (1%)
Query: 75 HPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVV 134
+P + A++S D TV++WD+E HQ + ++ +SP K + SG V
Sbjct: 471 NPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGK-YLASGSFDKCV 529
Query: 135 FCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISK 183
+ + H + IF C D V DG V ++D+ K
Sbjct: 530 HIWNTQSGNLVHSYRGTGGIF-EVCWNARGDKVGASASDGSVCVLDLRK 577
Score = 34.3 bits (77), Expect = 0.94
Identities = 38/152 (25%), Positives = 66/152 (43%), Gaps = 21/152 (13%)
Query: 557 DGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKT 616
DG +EI P+ K ++ H V +W+ +S L+ASGS ++ + NL
Sbjct: 215 DGEVEI---PSSKAT-VLRGHESEVFICAWN-------PVSDLLASGSGDSTARIWNLNE 263
Query: 617 VIESSPESPVTITEPYRTLSGHTAK----ITSVAWSPHHDGRLVSASYDGTAQVWDALRE 672
S+ S + GH +TS+ W+ + L + SYDG A++W +
Sbjct: 264 --NSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGT-LLATGSYDGFARIW--TED 318
Query: 673 EPLCNFRG-HRGRLLCVAWSPLDPDCIYSGAD 703
L + G H+G + + W+ + +G D
Sbjct: 319 GNLASTLGQHKGPIFALKWNRKGNYILSAGVD 350
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 60.8 bits (146), Expect = 9e-09
Identities = 49/211 (23%), Positives = 87/211 (41%), Gaps = 16/211 (7%)
Query: 59 ELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWS 118
E+V H VS G+ L AT DD V +W + + H + ++ +
Sbjct: 15 EIVAHASNVSSLVLGKASGR--LLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN 72
Query: 119 PRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVI 178
++LIV+G + G + + + + C + + VA G +D + +
Sbjct: 73 TP-EELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKL 131
Query: 179 IDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTK 238
DI +KG + R RGH + + + P G+ S + T + ++T G +++ P
Sbjct: 132 WDIRRKG-CVFRYRGHSQAVRCLRFSP-DGKWLASAADDHTVKLWDLTAGKMMSEFPGHT 189
Query: 239 G-----------CYLATGSKDQTIRIWSCSR 258
G LA+GS D+TIR W +
Sbjct: 190 GPVNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
Score = 59.7 bits (143), Expect = 2e-08
Identities = 46/166 (27%), Positives = 78/166 (46%), Gaps = 21/166 (12%)
Query: 545 KADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGS 604
KA G+++A G +D + ++ I I ++ H V ++ + PE L+ +GS
Sbjct: 30 KASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN-----TPE--ELIVAGS 82
Query: 605 NNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTA 664
+ I V +L+ + RTL GH A I S+ + P+ + + S S D
Sbjct: 83 QSGSIRVWDLEAA------------KILRTLMGHKANICSLDFHPYGEF-VASGSQDTNI 129
Query: 665 QVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKW 710
++WD R+ + +RGH + C+ +SP D + S ADD V W
Sbjct: 130 KLWDIRRKGCVFRYRGHSQAVRCLRFSP-DGKWLASAADDHTVKLW 174
Score = 45.4 bits (106), Expect = 4e-04
Identities = 54/218 (24%), Positives = 85/218 (38%), Gaps = 34/218 (15%)
Query: 239 GCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQ 298
G LATG D + +WS ++ +M L G P RL N P +
Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLT--------GHTSPVESVRL--------NTPEE 76
Query: 299 L-VSSCFGGELLQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSM 357
L V+ G + WDL ++ + TL + N+C L + + S S
Sbjct: 77 LIVAGSQSGSIRVWDL-EAAKILRTLMGHKA----------NICSLDFHPYGEFVASGSQ 125
Query: 358 DRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYD 417
D ++K WDI C + L FS D LA D +++W+ + K
Sbjct: 126 DTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSP-DGKWLASAADDHTVKLWDLTAGK---- 180
Query: 418 VKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYD 455
+ + + G V + +HP E LA G+ D + +D
Sbjct: 181 MMSEFPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFWD 217
Score = 45.4 bits (106), Expect = 4e-04
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 23/163 (14%)
Query: 549 KIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAV 608
+++ G++ GSI ++ + K++ T+ H + ++ +H +ASGS +
Sbjct: 76 ELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFH-------PYGEFVASGSQDTN 128
Query: 609 IYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGR-LVSASYDGTAQVW 667
I + +++ YR GH+ + + +SP DG+ L SA+ D T ++W
Sbjct: 129 IKLWDIRRK---------GCVFRYR---GHSQAVRCLRFSP--DGKWLASAADDHTVKLW 174
Query: 668 DALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKW 710
D + + F GH G + V + P + + SG+ D + W
Sbjct: 175 DLTAGKMMSEFPGHTGPVNVVEFHP-NEYLLASGSSDRTIRFW 216
Score = 39.7 bits (91), Expect = 0.022
Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 55 RVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTIST 114
+++ L+GH + F H G++ A+ S D +K+WD+ K V + H +
Sbjct: 96 KILRTLMGHKANICSLDF-HPYGEF--VASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRC 152
Query: 115 LHWSPRVKDLIVSGDEKGV 133
L +SP K L + D+ V
Sbjct: 153 LRFSPDGKWLASAADDHTV 171
Score = 35.4 bits (80), Expect = 0.42
Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 3/49 (6%)
Query: 55 RVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVT 103
+++ E GHT V+ F HP +Y L A+ S D T++ WD+E VV+
Sbjct: 180 KMMSEFPGHTGPVNVVEF--HPNEY-LLASGSSDRTIRFWDLEKFQVVS 225
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 59.3 bits (142), Expect = 3e-08
Identities = 55/254 (21%), Positives = 99/254 (38%), Gaps = 44/254 (17%)
Query: 469 HKKTVYTLAWGPPVPPMSLGGEGDRPS----LALYSCGGEGIVLQHNPWKLSGEAFDINK 524
H+ V+ AW P V + G GD + L S GG ++ + + G NK
Sbjct: 178 HESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNK 236
Query: 525 LIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTI 584
+ T + W +DG ++A+G+ DG I+ N L T+ QH + +
Sbjct: 237 DV-------------TSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFAL 282
Query: 585 SWHHE------------------HGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPV 626
W+ + H + + + S V + +N+ T S + +
Sbjct: 283 KWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNM-TFASCSTDMCI 341
Query: 627 TI-----TEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGH 681
+ P +T GHT ++ ++ W P L S S D T ++W ++ + + + H
Sbjct: 342 HVCRLGCDHPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDACVHDLQAH 400
Query: 682 RGRLLCVAWSPLDP 695
+ + WSP P
Sbjct: 401 SKEIYTIKWSPTGP 414
Score = 53.5 bits (127), Expect = 1e-06
Identities = 88/388 (22%), Positives = 149/388 (38%), Gaps = 74/388 (19%)
Query: 191 LRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQT 250
LRGH+ E+ AW P+ LA+GS D T
Sbjct: 175 LRGHESEVFICAWNPVSD--------------------------------LLASGSGDST 202
Query: 251 IRIWSCSRGR--GVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGEL 308
RIW+ + G L L R GG P+ K+ +L W S+ T L + G
Sbjct: 203 ARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVT--SLDWNSDG-TLLAMGSYDG-- 257
Query: 309 LQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIAT 368
+ W L AS+ GQ+ I L+ +LS +D+ WD T
Sbjct: 258 ----FARIWTENGNL--ASTLGQHKGPIF----ALKWNKKGNYVLSAGVDKTTIIWDAHT 307
Query: 369 LECSWTLPSLGGFAYSLAF-SSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKS 427
E P A + + +++ S + + + R + ++ VK F QG +
Sbjct: 308 GEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCR------LGCDHPVKTF-QGHTN 360
Query: 428 KVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSL 487
+V A+ W P+ LA +DD + ++ + H K +YT+ W P P S
Sbjct: 361 EVNAIKWDPSGM-LLASCSDDMTLKIWSMKQDACVHDLQA-HSKEIYTIKWSPTGPATS- 417
Query: 488 GGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKAD 547
S+ L S + V +D+ + + +K++ PV++ +++ D
Sbjct: 418 ---NPNSSIMLASASFDSTV----------RLWDVEQGVCTHTLMKHQEPVYS-VAFSPD 463
Query: 548 GKIMALGNEDGSIEIFQIPNLKLICTIQ 575
GK +A G+ D + I+ + L+ + Q
Sbjct: 464 GKYLASGSFDKYVHIWNTQSGSLVHSYQ 491
Score = 51.2 bits (121), Expect = 7e-06
Identities = 76/331 (22%), Positives = 134/331 (40%), Gaps = 56/331 (16%)
Query: 395 LAIGVGDGMIRVWNTLSIKNN--------YDVKNFWQGVKSK--VTALCWHPTKEGCLAF 444
LA G GD R+WN N + ++ V S VT+L W+ + LA
Sbjct: 194 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWN-SDGTLLAM 252
Query: 445 GTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGE 504
G+ DG ++ N + HK ++ L W + G D+ ++ + GE
Sbjct: 253 GSYDGFARIWTENGNLASTLGQ--HKGPIFALKWNKKGNYVLSAGV-DKTTIIWDAHTGE 309
Query: 505 GIVLQHNPWKLSGEAFDI---NKLIRDTNSIKYKLPV--------------HTE----IS 543
Q P+ S A D+ N + + S + V HT I
Sbjct: 310 A--KQQFPFH-SAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIK 366
Query: 544 WKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWH--HEHGSQPELSYLMA 601
W G ++A ++D +++I+ + + +Q H K + TI W S P S ++A
Sbjct: 367 WDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLA 426
Query: 602 SGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGR-LVSASY 660
S S ++ + + +++ + + TL H + SVA+SP DG+ L S S+
Sbjct: 427 SASFDSTVRLWDVEQGVCT------------HTLMKHQEPVYSVAFSP--DGKYLASGSF 472
Query: 661 DGTAQVWDALREEPLCNFRGHRGRLLCVAWS 691
D +W+ + +++G G + V W+
Sbjct: 473 DKYVHIWNTQSGSLVHSYQG-TGGIFEVCWN 502
Score = 45.1 bits (105), Expect = 5e-04
Identities = 89/379 (23%), Positives = 145/379 (38%), Gaps = 66/379 (17%)
Query: 108 HQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRND---SQHLFIEPRTIFCLTCSPH-- 162
H+ + W+P V DL+ SG + N N S L + C+ H
Sbjct: 178 HESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLR----HCIREGGHDV 232
Query: 163 --HED-----------LVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGE 209
++D L+A+G DG I ++ G + L H I ++ W G
Sbjct: 233 PSNKDVTSLDWNSDGTLLAMGSYDGFARIW--TENGNLASTLGQHKGPIFALKWNK-KGN 289
Query: 210 DCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPF 269
LS ++T+ + G A Q P L ++ + SCS + + +L
Sbjct: 290 YVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-MTFASCSTDMCIHVCRL-- 346
Query: 270 LKRRGGGIDPTVKERLWLT-----LHW-PSNQPTQLVSSCFGGELLQ-WDLTQSWRRKYT 322
G D VK T + W PS L++SC L+ W + Q
Sbjct: 347 ------GCDHPVKTFQGHTNEVNAIKWDPSGM---LLASCSDDMTLKIWSMKQD------ 391
Query: 323 LFSASSEGQNHSRIVFNLC-----PLQTEDDKQLLL-STSMDRDVKCWDIATLECSWTLP 376
+ + Q HS+ ++ + P + + ++L S S D V+ WD+ C+ TL
Sbjct: 392 --ACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLM 449
Query: 377 SLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHP 436
YS+AFS D LA G D + +WNT S + + +QG + +CW+
Sbjct: 450 KHQEPVYSVAFSP-DGKYLASGSFDKYVHIWNTQS----GSLVHSYQGT-GGIFEVCWN- 502
Query: 437 TKEGCLAFGTDDGKVGLYD 455
+ + DG V + D
Sbjct: 503 ARGDKVGASASDGSVCVLD 521
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/198 (21%), Positives = 67/198 (33%), Gaps = 76/198 (38%)
Query: 71 TFSHHPGQYN---------LCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRV 121
TF H + N L A+ SDD T+KIW ++ V + H I T+ WSP
Sbjct: 354 TFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTG 413
Query: 122 KDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDI 181
T +P+ ++A D V + D+
Sbjct: 414 P----------------------------------ATSNPNSSIMLASASFDSTVRLWDV 439
Query: 182 SKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCY 241
++G H L H + ++S+A+ P G Y
Sbjct: 440 -EQGVCTHTLMKHQEPVYSVAFSP--------------------------------DGKY 466
Query: 242 LATGSKDQTIRIWSCSRG 259
LA+GS D+ + IW+ G
Sbjct: 467 LASGSFDKYVHIWNTQSG 484
Score = 35.0 bits (79), Expect = 0.55
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 75 HPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVV 134
+P + A++S D TV++WDVE HQ + ++ +SP K L +K V
Sbjct: 418 NPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVH 477
Query: 135 FCYWFNRNDS-QHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDI 181
W ++ S H + IF C D V DG V ++D+
Sbjct: 478 I--WNTQSGSLVHSYQGTGGIF-EVCWNARGDKVGASASDGSVCVLDL 522
Score = 31.2 bits (69), Expect = 7.9
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 13/84 (15%)
Query: 635 LSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLD 694
L GH +++ AW+P D L S S D TA++W+ L E N G +L+
Sbjct: 175 LRGHESEVFICAWNPVSD-LLASGSGDSTARIWN-LNE----NSNGGSTQLVL------- 221
Query: 695 PDCIYSGADDFCVHKWLTSMQDHS 718
CI G D +K +TS+ +S
Sbjct: 222 RHCIREGGHDVPSNKDVTSLDWNS 245
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 59.3 bits (142), Expect = 3e-08
Identities = 55/254 (21%), Positives = 99/254 (38%), Gaps = 44/254 (17%)
Query: 469 HKKTVYTLAWGPPVPPMSLGGEGDRPS----LALYSCGGEGIVLQHNPWKLSGEAFDINK 524
H+ V+ AW P V + G GD + L S GG ++ + + G NK
Sbjct: 178 HESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNK 236
Query: 525 LIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTI 584
+ T + W +DG ++A+G+ DG I+ N L T+ QH + +
Sbjct: 237 DV-------------TSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFAL 282
Query: 585 SWHHE------------------HGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPV 626
W+ + H + + + S V + +N+ T S + +
Sbjct: 283 KWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNM-TFASCSTDMCI 341
Query: 627 TI-----TEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGH 681
+ P +T GHT ++ ++ W P L S S D T ++W ++ + + + H
Sbjct: 342 HVCRLGCDHPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDACVHDLQAH 400
Query: 682 RGRLLCVAWSPLDP 695
+ + WSP P
Sbjct: 401 SKEIYTIKWSPTGP 414
Score = 53.5 bits (127), Expect = 1e-06
Identities = 88/388 (22%), Positives = 149/388 (38%), Gaps = 74/388 (19%)
Query: 191 LRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQT 250
LRGH+ E+ AW P+ LA+GS D T
Sbjct: 175 LRGHESEVFICAWNPVSD--------------------------------LLASGSGDST 202
Query: 251 IRIWSCSRGR--GVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGEL 308
RIW+ + G L L R GG P+ K+ +L W S+ T L + G
Sbjct: 203 ARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVT--SLDWNSDG-TLLAMGSYDG-- 257
Query: 309 LQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIAT 368
+ W L AS+ GQ+ I L+ +LS +D+ WD T
Sbjct: 258 ----FARIWTENGNL--ASTLGQHKGPIF----ALKWNKKGNYVLSAGVDKTTIIWDAHT 307
Query: 369 LECSWTLPSLGGFAYSLAF-SSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKS 427
E P A + + +++ S + + + R + ++ VK F QG +
Sbjct: 308 GEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCR------LGCDHPVKTF-QGHTN 360
Query: 428 KVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSL 487
+V A+ W P+ LA +DD + ++ + H K +YT+ W P P S
Sbjct: 361 EVNAIKWDPSGM-LLASCSDDMTLKIWSMKQDACVHDLQA-HSKEIYTIKWSPTGPATS- 417
Query: 488 GGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKAD 547
S+ L S + V +D+ + + +K++ PV++ +++ D
Sbjct: 418 ---NPNSSIMLASASFDSTV----------RLWDVEQGVCTHTLMKHQEPVYS-VAFSPD 463
Query: 548 GKIMALGNEDGSIEIFQIPNLKLICTIQ 575
GK +A G+ D + I+ + L+ + Q
Sbjct: 464 GKYLASGSFDKYVHIWNTQSGSLVHSYQ 491
Score = 51.2 bits (121), Expect = 7e-06
Identities = 76/331 (22%), Positives = 134/331 (40%), Gaps = 56/331 (16%)
Query: 395 LAIGVGDGMIRVWNTLSIKNN--------YDVKNFWQGVKSK--VTALCWHPTKEGCLAF 444
LA G GD R+WN N + ++ V S VT+L W+ + LA
Sbjct: 194 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWN-SDGTLLAM 252
Query: 445 GTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGE 504
G+ DG ++ N + HK ++ L W + G D+ ++ + GE
Sbjct: 253 GSYDGFARIWTENGNLASTLGQ--HKGPIFALKWNKKGNYVLSAGV-DKTTIIWDAHTGE 309
Query: 505 GIVLQHNPWKLSGEAFDI---NKLIRDTNSIKYKLPV--------------HTE----IS 543
Q P+ S A D+ N + + S + V HT I
Sbjct: 310 A--KQQFPFH-SAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIK 366
Query: 544 WKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWH--HEHGSQPELSYLMA 601
W G ++A ++D +++I+ + + +Q H K + TI W S P S ++A
Sbjct: 367 WDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLA 426
Query: 602 SGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGR-LVSASY 660
S S ++ + + +++ + + TL H + SVA+SP DG+ L S S+
Sbjct: 427 SASFDSTVRLWDVEQGVCT------------HTLMKHQEPVYSVAFSP--DGKYLASGSF 472
Query: 661 DGTAQVWDALREEPLCNFRGHRGRLLCVAWS 691
D +W+ + +++G G + V W+
Sbjct: 473 DKYVHIWNTQSGSLVHSYQG-TGGIFEVCWN 502
Score = 45.1 bits (105), Expect = 5e-04
Identities = 89/379 (23%), Positives = 145/379 (38%), Gaps = 66/379 (17%)
Query: 108 HQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRND---SQHLFIEPRTIFCLTCSPH-- 162
H+ + W+P V DL+ SG + N N S L + C+ H
Sbjct: 178 HESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLR----HCIREGGHDV 232
Query: 163 --HED-----------LVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGE 209
++D L+A+G DG I ++ G + L H I ++ W G
Sbjct: 233 PSNKDVTSLDWNSDGTLLAMGSYDGFARIW--TENGNLASTLGQHKGPIFALKWNK-KGN 289
Query: 210 DCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPF 269
LS ++T+ + G A Q P L ++ + SCS + + +L
Sbjct: 290 YVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-MTFASCSTDMCIHVCRL-- 346
Query: 270 LKRRGGGIDPTVKERLWLT-----LHW-PSNQPTQLVSSCFGGELLQ-WDLTQSWRRKYT 322
G D VK T + W PS L++SC L+ W + Q
Sbjct: 347 ------GCDHPVKTFQGHTNEVNAIKWDPSGM---LLASCSDDMTLKIWSMKQD------ 391
Query: 323 LFSASSEGQNHSRIVFNLC-----PLQTEDDKQLLL-STSMDRDVKCWDIATLECSWTLP 376
+ + Q HS+ ++ + P + + ++L S S D V+ WD+ C+ TL
Sbjct: 392 --ACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLM 449
Query: 377 SLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHP 436
YS+AFS D LA G D + +WNT S + + +QG + +CW+
Sbjct: 450 KHQEPVYSVAFSP-DGKYLASGSFDKYVHIWNTQS----GSLVHSYQGT-GGIFEVCWN- 502
Query: 437 TKEGCLAFGTDDGKVGLYD 455
+ + DG V + D
Sbjct: 503 ARGDKVGASASDGSVCVLD 521
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/198 (21%), Positives = 67/198 (33%), Gaps = 76/198 (38%)
Query: 71 TFSHHPGQYN---------LCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRV 121
TF H + N L A+ SDD T+KIW ++ V + H I T+ WSP
Sbjct: 354 TFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTG 413
Query: 122 KDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDI 181
T +P+ ++A D V + D+
Sbjct: 414 P----------------------------------ATSNPNSSIMLASASFDSTVRLWDV 439
Query: 182 SKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCY 241
++G H L H + ++S+A+ P G Y
Sbjct: 440 -EQGVCTHTLMKHQEPVYSVAFSP--------------------------------DGKY 466
Query: 242 LATGSKDQTIRIWSCSRG 259
LA+GS D+ + IW+ G
Sbjct: 467 LASGSFDKYVHIWNTQSG 484
Score = 35.0 bits (79), Expect = 0.55
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 75 HPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVV 134
+P + A++S D TV++WDVE HQ + ++ +SP K L +K V
Sbjct: 418 NPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVH 477
Query: 135 FCYWFNRNDS-QHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDI 181
W ++ S H + IF C D V DG V ++D+
Sbjct: 478 I--WNTQSGSLVHSYQGTGGIF-EVCWNARGDKVGASASDGSVCVLDL 522
Score = 31.2 bits (69), Expect = 7.9
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 13/84 (15%)
Query: 635 LSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLD 694
L GH +++ AW+P D L S S D TA++W+ L E N G +L+
Sbjct: 175 LRGHESEVFICAWNPVSD-LLASGSGDSTARIWN-LNE----NSNGGSTQLVL------- 221
Query: 695 PDCIYSGADDFCVHKWLTSMQDHS 718
CI G D +K +TS+ +S
Sbjct: 222 RHCIREGGHDVPSNKDVTSLDWNS 245
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 59.3 bits (142), Expect = 3e-08
Identities = 55/254 (21%), Positives = 99/254 (38%), Gaps = 44/254 (17%)
Query: 469 HKKTVYTLAWGPPVPPMSLGGEGDRPS----LALYSCGGEGIVLQHNPWKLSGEAFDINK 524
H+ V+ AW P V + G GD + L S GG ++ + + G NK
Sbjct: 178 HESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNK 236
Query: 525 LIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTI 584
+ T + W +DG ++A+G+ DG I+ N L T+ QH + +
Sbjct: 237 DV-------------TSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIFAL 282
Query: 585 SWHHE------------------HGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPV 626
W+ + H + + + S V + +N+ T S + +
Sbjct: 283 KWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNM-TFASCSTDMCI 341
Query: 627 TI-----TEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGH 681
+ P +T GHT ++ ++ W P L S S D T ++W ++ + + + H
Sbjct: 342 HVCRLGCDHPVKTFQGHTNEVNAIKWDP-SGMLLASCSDDMTLKIWSMKQDACVHDLQAH 400
Query: 682 RGRLLCVAWSPLDP 695
+ + WSP P
Sbjct: 401 SKEIYTIKWSPTGP 414
Score = 53.5 bits (127), Expect = 1e-06
Identities = 88/388 (22%), Positives = 149/388 (38%), Gaps = 74/388 (19%)
Query: 191 LRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQT 250
LRGH+ E+ AW P+ LA+GS D T
Sbjct: 175 LRGHESEVFICAWNPVSD--------------------------------LLASGSGDST 202
Query: 251 IRIWSCSRGR--GVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQLVSSCFGGEL 308
RIW+ + G L L R GG P+ K+ +L W S+ T L + G
Sbjct: 203 ARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVT--SLDWNSDG-TLLAMGSYDG-- 257
Query: 309 LQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIAT 368
+ W L AS+ GQ+ I L+ +LS +D+ WD T
Sbjct: 258 ----FARIWTENGNL--ASTLGQHKGPIF----ALKWNKKGNYVLSAGVDKTTIIWDAHT 307
Query: 369 LECSWTLPSLGGFAYSLAF-SSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKS 427
E P A + + +++ S + + + R + ++ VK F QG +
Sbjct: 308 GEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCR------LGCDHPVKTF-QGHTN 360
Query: 428 KVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSL 487
+V A+ W P+ LA +DD + ++ + H K +YT+ W P P S
Sbjct: 361 EVNAIKWDPSGM-LLASCSDDMTLKIWSMKQDACVHDLQA-HSKEIYTIKWSPTGPATS- 417
Query: 488 GGEGDRPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKAD 547
S+ L S + V +D+ + + +K++ PV++ +++ D
Sbjct: 418 ---NPNSSIMLASASFDSTV----------RLWDVEQGVCTHTLMKHQEPVYS-VAFSPD 463
Query: 548 GKIMALGNEDGSIEIFQIPNLKLICTIQ 575
GK +A G+ D + I+ + L+ + Q
Sbjct: 464 GKYLASGSFDKYVHIWNTQSGSLVHSYQ 491
Score = 51.2 bits (121), Expect = 7e-06
Identities = 76/331 (22%), Positives = 134/331 (40%), Gaps = 56/331 (16%)
Query: 395 LAIGVGDGMIRVWNTLSIKNN--------YDVKNFWQGVKSK--VTALCWHPTKEGCLAF 444
LA G GD R+WN N + ++ V S VT+L W+ + LA
Sbjct: 194 LASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWN-SDGTLLAM 252
Query: 445 GTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGE 504
G+ DG ++ N + HK ++ L W + G D+ ++ + GE
Sbjct: 253 GSYDGFARIWTENGNLASTLGQ--HKGPIFALKWNKKGNYVLSAGV-DKTTIIWDAHTGE 309
Query: 505 GIVLQHNPWKLSGEAFDI---NKLIRDTNSIKYKLPV--------------HTE----IS 543
Q P+ S A D+ N + + S + V HT I
Sbjct: 310 A--KQQFPFH-SAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIK 366
Query: 544 WKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWH--HEHGSQPELSYLMA 601
W G ++A ++D +++I+ + + +Q H K + TI W S P S ++A
Sbjct: 367 WDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLA 426
Query: 602 SGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGR-LVSASY 660
S S ++ + + +++ + + TL H + SVA+SP DG+ L S S+
Sbjct: 427 SASFDSTVRLWDVEQGVCT------------HTLMKHQEPVYSVAFSP--DGKYLASGSF 472
Query: 661 DGTAQVWDALREEPLCNFRGHRGRLLCVAWS 691
D +W+ + +++G G + V W+
Sbjct: 473 DKYVHIWNTQSGSLVHSYQG-TGGIFEVCWN 502
Score = 45.1 bits (105), Expect = 5e-04
Identities = 89/379 (23%), Positives = 145/379 (38%), Gaps = 66/379 (17%)
Query: 108 HQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRND---SQHLFIEPRTIFCLTCSPH-- 162
H+ + W+P V DL+ SG + N N S L + C+ H
Sbjct: 178 HESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLR----HCIREGGHDV 232
Query: 163 --HED-----------LVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGE 209
++D L+A+G DG I ++ G + L H I ++ W G
Sbjct: 233 PSNKDVTSLDWNSDGTLLAMGSYDGFARIW--TENGNLASTLGQHKGPIFALKWNK-KGN 289
Query: 210 DCLSINQEETSEEAEITNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPF 269
LS ++T+ + G A Q P L ++ + SCS + + +L
Sbjct: 290 YVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNN-MTFASCSTDMCIHVCRL-- 346
Query: 270 LKRRGGGIDPTVKERLWLT-----LHW-PSNQPTQLVSSCFGGELLQ-WDLTQSWRRKYT 322
G D VK T + W PS L++SC L+ W + Q
Sbjct: 347 ------GCDHPVKTFQGHTNEVNAIKWDPSGM---LLASCSDDMTLKIWSMKQD------ 391
Query: 323 LFSASSEGQNHSRIVFNLC-----PLQTEDDKQLLL-STSMDRDVKCWDIATLECSWTLP 376
+ + Q HS+ ++ + P + + ++L S S D V+ WD+ C+ TL
Sbjct: 392 --ACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLM 449
Query: 377 SLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHP 436
YS+AFS D LA G D + +WNT S + + +QG + +CW+
Sbjct: 450 KHQEPVYSVAFSP-DGKYLASGSFDKYVHIWNTQS----GSLVHSYQGT-GGIFEVCWN- 502
Query: 437 TKEGCLAFGTDDGKVGLYD 455
+ + DG V + D
Sbjct: 503 ARGDKVGASASDGSVCVLD 521
Score = 42.0 bits (97), Expect = 0.004
Identities = 43/198 (21%), Positives = 67/198 (33%), Gaps = 76/198 (38%)
Query: 71 TFSHHPGQYN---------LCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRV 121
TF H + N L A+ SDD T+KIW ++ V + H I T+ WSP
Sbjct: 354 TFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTG 413
Query: 122 KDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDI 181
T +P+ ++A D V + D+
Sbjct: 414 P----------------------------------ATSNPNSSIMLASASFDSTVRLWDV 439
Query: 182 SKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCY 241
++G H L H + ++S+A+ P G Y
Sbjct: 440 -EQGVCTHTLMKHQEPVYSVAFSP--------------------------------DGKY 466
Query: 242 LATGSKDQTIRIWSCSRG 259
LA+GS D+ + IW+ G
Sbjct: 467 LASGSFDKYVHIWNTQSG 484
Score = 35.0 bits (79), Expect = 0.55
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 75 HPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVV 134
+P + A++S D TV++WDVE HQ + ++ +SP K L +K V
Sbjct: 418 NPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVH 477
Query: 135 FCYWFNRNDS-QHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDI 181
W ++ S H + IF C D V DG V ++D+
Sbjct: 478 I--WNTQSGSLVHSYQGTGGIF-EVCWNARGDKVGASASDGSVCVLDL 522
Score = 31.2 bits (69), Expect = 7.9
Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 13/84 (15%)
Query: 635 LSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLD 694
L GH +++ AW+P D L S S D TA++W+ L E N G +L+
Sbjct: 175 LRGHESEVFICAWNPVSD-LLASGSGDSTARIWN-LNE----NSNGGSTQLVL------- 221
Query: 695 PDCIYSGADDFCVHKWLTSMQDHS 718
CI G D +K +TS+ +S
Sbjct: 222 RHCIREGGHDVPSNKDVTSLDWNS 245
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 58.5 bits (140), Expect = 5e-08
Identities = 54/218 (24%), Positives = 89/218 (40%), Gaps = 41/218 (18%)
Query: 60 LVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSP 119
L GHT+ V +F H L A+ S D T+K+WD + + H H +S++ P
Sbjct: 146 LKGHTDSVQDISFDHSG---KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMP 202
Query: 120 RVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHED------------LV 167
++ + +K + W E +T +C+ H + L+
Sbjct: 203 NGDHIVSASRDKTIKM--W-----------EVQTGYCVKTFTGHREWVRMVRPNQDGTLI 249
Query: 168 AIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITN 227
A D V + ++ K E LR H+ + I+W P E S E T E + +
Sbjct: 250 ASCSNDQTVRVWVVATK-ECKAELREHEHVVECISWAP---ESSYSSISEATGSETKKSG 305
Query: 228 GNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMIL 265
G +L +GS+D+TI++W S G +M L
Sbjct: 306 ---------KPGPFLLSGSRDKTIKMWDVSTGMCLMTL 334
Score = 45.1 bits (105), Expect = 5e-04
Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 26/170 (15%)
Query: 528 DTNSIKYKLPVHTE----ISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNT 583
+T + L HT+ IS+ GK++A + D +I+++ + I T+ H V++
Sbjct: 138 ETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSS 197
Query: 584 ISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKIT 643
++ +M +G + ++ KT+ ++ + +T +GH +
Sbjct: 198 VA-------------IMPNGDH--IVSASRDKTIKMWEVQTGYCV----KTFTGHREWVR 238
Query: 644 SVAWSPHHDGRLV-SASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSP 692
V P+ DG L+ S S D T +VW +E R H + C++W+P
Sbjct: 239 MVR--PNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAP 286
Score = 42.4 bits (98), Expect = 0.003
Identities = 85/396 (21%), Positives = 139/396 (35%), Gaps = 126/396 (31%)
Query: 60 LVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSP 119
L GH V+ F HP +++ ++S+D T+K+WD ET E L HT S
Sbjct: 104 LSGHRSPVTRVIF--HP-VFSVMVSASEDATIKVWDYETGDF--ERTLKGHTDS------ 152
Query: 120 RVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVII 179
V+D +S D G + +CS D + +
Sbjct: 153 -VQD--ISFDHSGKLLA---------------------SCSA-----------DMTIKLW 177
Query: 180 DISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKG 239
D + E I + GHD + S+A P G
Sbjct: 178 DF-QGFECIRTMHGHDHNVSSVAIMP--------------------------------NG 204
Query: 240 CYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTLHWPSNQPTQL 299
++ + S+D+TI++W G V R W+ + P NQ L
Sbjct: 205 DHIVSASRDKTIKMWEVQTGYCVKTF---------------TGHREWVRMVRP-NQDGTL 248
Query: 300 VSSCFGGELLQ-WDLTQ-----------------SWRRKYTLFSASSEGQNHSRIVFNLC 341
++SC + ++ W + SW + + S S + ++
Sbjct: 249 IASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETK------ 302
Query: 342 PLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGD 401
++ LLS S D+ +K WD++T C TL + + F S L+ D
Sbjct: 303 --KSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSC-ADD 359
Query: 402 GMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPT 437
+RVW+ KN +K + VT+L +H T
Sbjct: 360 KTLRVWD---YKNKRCMKTL-NAHEHFVTSLDFHKT 391
Score = 34.3 bits (77), Expect = 0.94
Identities = 48/245 (19%), Positives = 93/245 (37%), Gaps = 25/245 (10%)
Query: 350 QLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNT 409
+LL S S D +K WD EC T+ S+A + + D I++W
Sbjct: 163 KLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMP-NGDHIVSASRDKTIKMW-- 219
Query: 410 LSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYH 469
++ Y VK F G + V + P ++G L + + + K + H
Sbjct: 220 -EVQTGYCVKTF-TGHREWVRMV--RPNQDGTLIASCSNDQTVRVWVVATKECKAELREH 275
Query: 470 KKTVYTLAWGPPVPPMSL----GGE---GDRPSLALYSCGGEGIVLQHNPWKLSGEAFDI 522
+ V ++W P S+ G E +P L S + + W +S +
Sbjct: 276 EHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTI---KMWDVS-TGMCL 331
Query: 523 NKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVN 582
L+ N ++ + + + GK + +D ++ ++ N + + T+ H V
Sbjct: 332 MTLVGHDNWVR-------GVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVT 384
Query: 583 TISWH 587
++ +H
Sbjct: 385 SLDFH 389
Score = 32.7 bits (73), Expect = 2.7
Identities = 37/178 (20%), Positives = 73/178 (41%), Gaps = 29/178 (16%)
Query: 547 DGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEH---------GSQPELS 597
DG ++A + D ++ ++ + + +++H +V ISW E GS+ + S
Sbjct: 245 DGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKS 304
Query: 598 ----YLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDG 653
+ SGS + I + ++ T + TL GH + V + H G
Sbjct: 305 GKPGPFLLSGSRDKTIKMWDVSTGM------------CLMTLVGHDNWVRGVLF--HSGG 350
Query: 654 R-LVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKW 710
+ ++S + D T +VWD + + H + + + P + +G+ D V W
Sbjct: 351 KFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAP-YVVTGSVDQTVKVW 407
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 58.5 bits (140), Expect = 5e-08
Identities = 51/188 (27%), Positives = 83/188 (44%), Gaps = 28/188 (14%)
Query: 540 TEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYL 599
T+ S A ++ + + S E+ + PN L CT+ H + V+++ + P +L
Sbjct: 3 TKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKF------SPNGEWL 56
Query: 600 MASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSAS 659
+S ++ +I E +TL GH +I+ VAWS RLVSAS
Sbjct: 57 ASSSADRLIIIWGAYDGKYE-------------KTLYGHNLEISDVAWSSD-SSRLVSAS 102
Query: 660 YDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKW-------LT 712
D T ++WD + L +GH + C ++P + I SG+ D V W L
Sbjct: 103 DDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNP-PSNLIISGSFDETVKIWEVKTGKCLK 161
Query: 713 SMQDHSRP 720
++ HS P
Sbjct: 162 TLSAHSDP 169
Score = 53.5 bits (127), Expect = 1e-06
Identities = 59/228 (25%), Positives = 97/228 (42%), Gaps = 22/228 (9%)
Query: 47 ESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHA 106
E P P + + LVGHTE VS FS + G++ A+SS D + IW
Sbjct: 24 EVPENPNYALKCTLVGHTEAVSSVKFSPN-GEW--LASSSADRLIIIWGAYDGKYEKTLY 80
Query: 107 LHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRNDS--QHLFIEPRTIFCLTCSPHHE 164
H IS + WS L+ + D+K + W R+ + L +FC +P
Sbjct: 81 GHNLEISDVAWSSDSSRLVSASDDKTLKL--WDVRSGKCLKTLKGHSNYVFCCNFNPP-S 137
Query: 165 DLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAE 224
+L+ G D V I ++ K G+ + L H D + ++ + G +S + + +
Sbjct: 138 NLIISGSFDETVKIWEV-KTGKCLKTLSAHSDPVSAVHF-NCSGSLIVSGSYDGLCRIWD 195
Query: 225 ITNGNAVA------QAPVT------KGCYLATGSKDQTIRIWSCSRGR 260
+G + PV+ G Y+ T + D T+++W SRGR
Sbjct: 196 AASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGR 243
Score = 41.2 bits (95), Expect = 0.008
Identities = 45/221 (20%), Positives = 94/221 (42%), Gaps = 41/221 (18%)
Query: 540 TEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYL 599
++++W +D + ++D +++++ + + K + T++ H V +++ S L
Sbjct: 87 SDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPP-------SNL 139
Query: 600 MASGSNNAVIYVHNLKT-------VIESSPESPV--------TITEPYRTL-------SG 637
+ SGS + + + +KT S P S V ++ Y L SG
Sbjct: 140 IISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASG 199
Query: 638 HTAK---------ITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCV 688
K ++ V +SP+ +++A+ D T ++WD R L + GH+ C+
Sbjct: 200 QCLKTLVDDDNPPVSFVKFSPNGK-YILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCI 258
Query: 689 --AWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQGKKSI 727
+S I SG++D V+ W ++ + QG +
Sbjct: 259 FANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV 299
>gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]
Length = 498
Score = 56.6 bits (135), Expect = 2e-07
Identities = 66/299 (22%), Positives = 121/299 (40%), Gaps = 41/299 (13%)
Query: 389 SVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDD 448
S D LA G D + +W + + +G V+ + W P +A G DD
Sbjct: 201 SNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDD 260
Query: 449 -GKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGIV 507
++ L++ + + S H+ ++ ++AW P GG+ + Y C +G +
Sbjct: 261 CSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQ----FYQCDLDGNL 316
Query: 508 LQHNP-------WKLSGE----AFDINKLIR--------DTNSIKYKLPVHTEISWKADG 548
L W LS A D ++ IR D N ++ P+ + + +G
Sbjct: 317 LDSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTDRNIVQEDHPIMS-FTISKNG 375
Query: 549 KIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAV 608
++ L + ++ + + L+ Q + TI H G E +ASGS +
Sbjct: 376 RLALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTI--HSCFGGHNE--DFIASGSEDHK 431
Query: 609 IYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVW 667
+Y+ + ++ + P L+GHT + V+W+P + SAS DGT ++W
Sbjct: 432 VYIWHKRSEL------------PIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIW 478
Score = 36.6 bits (83), Expect = 0.19
Identities = 14/52 (26%), Positives = 28/52 (53%)
Query: 83 ATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVV 134
A+ S+D V IW ++ + E H T++ + W+P++ ++ S + G V
Sbjct: 424 ASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTV 475
Score = 35.0 bits (79), Expect = 0.55
Identities = 18/38 (47%), Positives = 25/38 (65%), Gaps = 2/38 (5%)
Query: 57 IGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIW 94
I EL GHT V+ S +P ++ A++SDDGTV+IW
Sbjct: 443 IAELTGHTRTVN--CVSWNPQIPSMMASASDDGTVRIW 478
Score = 32.7 bits (73), Expect = 2.7
Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
Query: 91 VKIWDVETKTVVTEHALHQHTISTLH--WSPRVKDLIVSGDEKGVVFCYWFNRNDSQ--H 146
V +WD++ + +V ++ T+H + +D I SG E V+ W R++
Sbjct: 387 VHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYI-WHKRSELPIAE 445
Query: 147 LFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVI 178
L RT+ C++ +P ++A DG V I
Sbjct: 446 LTGHTRTVNCVSWNPQIPSMMASASDDGTVRI 477
Score = 32.3 bits (72), Expect = 3.6
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 651 HDG-RLVSASYDGTAQVW----DALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDF 705
+DG +L + S D T +W D + L GH + +AWSP D + G DD
Sbjct: 202 NDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDD- 260
Query: 706 CVHKWLTSMQ 715
C WL ++Q
Sbjct: 261 CSELWLWNVQ 270
>gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]
Length = 514
Score = 56.6 bits (135), Expect = 2e-07
Identities = 66/299 (22%), Positives = 121/299 (40%), Gaps = 41/299 (13%)
Query: 389 SVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDD 448
S D LA G D + +W + + +G V+ + W P +A G DD
Sbjct: 217 SNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDD 276
Query: 449 -GKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGIV 507
++ L++ + + S H+ ++ ++AW P GG+ + Y C +G +
Sbjct: 277 CSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQ----FYQCDLDGNL 332
Query: 508 LQHNP-------WKLSGE----AFDINKLIR--------DTNSIKYKLPVHTEISWKADG 548
L W LS A D ++ IR D N ++ P+ + + +G
Sbjct: 333 LDSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTDRNIVQEDHPIMS-FTISKNG 391
Query: 549 KIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAV 608
++ L + ++ + + L+ Q + TI H G E +ASGS +
Sbjct: 392 RLALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTI--HSCFGGHNE--DFIASGSEDHK 447
Query: 609 IYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVW 667
+Y+ + ++ + P L+GHT + V+W+P + SAS DGT ++W
Sbjct: 448 VYIWHKRSEL------------PIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIW 494
Score = 36.6 bits (83), Expect = 0.19
Identities = 14/52 (26%), Positives = 28/52 (53%)
Query: 83 ATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVV 134
A+ S+D V IW ++ + E H T++ + W+P++ ++ S + G V
Sbjct: 440 ASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTV 491
Score = 35.0 bits (79), Expect = 0.55
Identities = 18/38 (47%), Positives = 25/38 (65%), Gaps = 2/38 (5%)
Query: 57 IGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIW 94
I EL GHT V+ S +P ++ A++SDDGTV+IW
Sbjct: 459 IAELTGHTRTVN--CVSWNPQIPSMMASASDDGTVRIW 494
Score = 32.7 bits (73), Expect = 2.7
Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 5/92 (5%)
Query: 91 VKIWDVETKTVVTEHALHQHTISTLH--WSPRVKDLIVSGDEKGVVFCYWFNRNDSQ--H 146
V +WD++ + +V ++ T+H + +D I SG E V+ W R++
Sbjct: 403 VHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYI-WHKRSELPIAE 461
Query: 147 LFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVI 178
L RT+ C++ +P ++A DG V I
Sbjct: 462 LTGHTRTVNCVSWNPQIPSMMASASDDGTVRI 493
Score = 32.3 bits (72), Expect = 3.6
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 651 HDG-RLVSASYDGTAQVW----DALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDF 705
+DG +L + S D T +W D + L GH + +AWSP D + G DD
Sbjct: 218 NDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDD- 276
Query: 706 CVHKWLTSMQ 715
C WL ++Q
Sbjct: 277 CSELWLWNVQ 286
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 56.2 bits (134), Expect = 2e-07
Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 631 PYRTLSGHTAKITSVAWSPHHDGRLV-SASYDGTAQVWDALREEPLCNFRGHRGRLLCVA 689
P + H ++ SV WS +LV S S+D T ++WD + LC FRGH +
Sbjct: 103 PLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTI 162
Query: 690 WSPLDPDCIYSGADDFCVHKW 710
WSP P C S + D + W
Sbjct: 163 WSPHIPGCFASASGDQTLRIW 183
Score = 54.3 bits (129), Expect = 9e-07
Identities = 38/172 (22%), Positives = 73/172 (42%), Gaps = 19/172 (11%)
Query: 541 EISWKADGK-IMALGNEDGSIEIFQIPNLK-LICTIQQHHKLVNTISWHHEHGSQPELSY 598
+++W + + ++ + DGS++++ + ++H + V ++ W G Q
Sbjct: 72 DVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQ----- 126
Query: 599 LMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSA 658
L+ SGS + + + + T+ + T GH + I S WSPH G SA
Sbjct: 127 LVVSGSWDQTVKLWD------------PTVGKSLCTFRGHESIIYSTIWSPHIPGCFASA 174
Query: 659 SYDGTAQVWDALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKW 710
S D T ++WD H+ +L W + + + +GA D + W
Sbjct: 175 SGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGW 226
Score = 50.8 bits (120), Expect = 1e-05
Identities = 46/220 (20%), Positives = 91/220 (41%), Gaps = 27/220 (12%)
Query: 498 LYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNED 557
L +C G+G + + K +G + ++ S+ + S +++ G+ D
Sbjct: 83 LITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDW--------SQTRGEQLVVSGSWD 134
Query: 558 GSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTV 617
+++++ K +CT + H ++ + W P + AS S + + + ++K
Sbjct: 135 QTVKLWDPTVGKSLCTFRGHESIIYSTIW------SPHIPGCFASASGDQTLRIWDVKA- 187
Query: 618 IESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALR-EEPLC 676
+ V I P H A+I S W +++ LV+ + D + + WD +P+
Sbjct: 188 ------AGVRIVIP-----AHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVF 236
Query: 677 NFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQD 716
GH + V +SP + S + DF V W S D
Sbjct: 237 ELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPD 276
Score = 43.5 bits (101), Expect = 0.002
Identities = 49/204 (24%), Positives = 84/204 (41%), Gaps = 38/204 (18%)
Query: 124 LIVSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISK 183
LI+ DE G+ F+ ND +F +T S ++E ++ DG + + D +K
Sbjct: 49 LILDPDEAGLRLFRSFDWNDG---------LFDVTWSENNEHVLITCSGDGSLQLWDTAK 99
Query: 184 KGEVIHRLRGHDDEIHSIAWCPLPGED-CLSINQEETSEEAEITNGNAVAQ--------- 233
+ + H E++S+ W GE +S + ++T + + T G ++
Sbjct: 100 AAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIY 159
Query: 234 ----APVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERLWLTL 289
+P GC+ A+ S DQT+RIW + GV I + P + + L+
Sbjct: 160 STIWSPHIPGCF-ASASGDQTLRIWDV-KAAGVRI------------VIPAHQAEI-LSC 204
Query: 290 HWPSNQPTQLVSSCFGGELLQWDL 313
W LV+ L WDL
Sbjct: 205 DWCKYNENLLVTGAVDCSLRGWDL 228
Score = 37.7 bits (86), Expect = 0.085
Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 14/142 (9%)
Query: 62 GHTERVSGFTFSHH-PGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPR 120
GH + +S H PG + A++S D T++IWDV+ V HQ I + W
Sbjct: 153 GHESIIYSTIWSPHIPGCF---ASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKY 209
Query: 121 VKDLIVSGDEKGVVFCY---WFNRNDSQHLFI---EPRTIFCLTCSPHHEDLVAIGYKDG 174
++L+V+ G V C W RN Q +F I + SP H ++A D
Sbjct: 210 NENLLVT----GAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDF 265
Query: 175 IVVIIDISKKGEVIHRLRGHDD 196
V + SK ++ + H +
Sbjct: 266 TVRFWNFSKPDSLLETVEHHTE 287
Score = 36.2 bits (82), Expect = 0.25
Identities = 34/147 (23%), Positives = 57/147 (38%), Gaps = 8/147 (5%)
Query: 63 HTERVSGFTFSHHPGQYNLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVK 122
H + V +S G+ L + S D TVK+WD + H+ I + WSP +
Sbjct: 110 HAQEVYSVDWSQTRGE-QLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIP 168
Query: 123 DLI--VSGDEKGVVFCYWFNRNDSQHLFIEPRTIFCLTCS--PHHEDLVAIGYKDGIVVI 178
SGD+ W + + I L+C ++E+L+ G D +
Sbjct: 169 GCFASASGDQ---TLRIWDVKAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRG 225
Query: 179 IDISKKGEVIHRLRGHDDEIHSIAWCP 205
D+ + + L GH I + + P
Sbjct: 226 WDLRNVRQPVFELLGHTYAIRRVKFSP 252
Score = 33.9 bits (76), Expect = 1.2
Identities = 25/108 (23%), Positives = 48/108 (44%), Gaps = 6/108 (5%)
Query: 400 GDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTK-EGCLAFGTDDGKVGLYDTYS 458
GDG +++W+T V ++ +V ++ W T+ E + G+ D V L+D
Sbjct: 88 GDGSLQLWDTAKAAGPLQV---YKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTV 144
Query: 459 NKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGI 506
K + H+ +Y+ W P +P GD+ +L ++ G+
Sbjct: 145 GKS-LCTFRGHESIIYSTIWSPHIPGCFASASGDQ-TLRIWDVKAAGV 190
Score = 33.1 bits (74), Expect = 2.1
Identities = 51/195 (26%), Positives = 72/195 (36%), Gaps = 25/195 (12%)
Query: 84 TSSDDGTVKIWDVETKT----VVTEHALHQHTISTLHWS-PRVKDLIVSGDEKGVVFCYW 138
T S DG++++WD V EHA +++ WS R + L+VSG V +
Sbjct: 85 TCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVD---WSQTRGEQLVVSGSWDQTVKLWD 141
Query: 139 FNRNDSQHLFIEPRTIFCLTC-SPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDE 197
S F +I T SPH A D + I D+ G I + H E
Sbjct: 142 PTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRI-VIPAHQAE 200
Query: 198 IHSIAW--------------CPLPGEDCLSINQEETSEEAEITNGNAVAQAPVTKGCYLA 243
I S W C L G D ++ Q V +P LA
Sbjct: 201 ILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPF-HASVLA 259
Query: 244 TGSKDQTIRIWSCSR 258
+ S D T+R W+ S+
Sbjct: 260 SCSYDFTVRFWNFSK 274
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 55.8 bits (133), Expect = 3e-07
Identities = 33/119 (27%), Positives = 61/119 (51%), Gaps = 5/119 (4%)
Query: 609 IYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWD 668
I V+ TVI+ + V I P ++ ++ KI+ ++WS +H L S+ Y+GT +WD
Sbjct: 445 IKVYEYDTVIQDA----VDIHYPENEMTCNS-KISCISWSSYHKNLLASSDYEGTVILWD 499
Query: 669 ALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQGKKSI 727
+ ++ H R V ++ +DP + SG+DD V W T++ + + K ++
Sbjct: 500 GFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANV 558
Score = 43.9 bits (102), Expect = 0.001
Identities = 35/127 (27%), Positives = 56/127 (44%), Gaps = 9/127 (7%)
Query: 349 KQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWN 408
K LL S+ + V WD T + S +S+ F+ +D LA G D +++W+
Sbjct: 483 KNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWS 542
Query: 409 TLSIKNNYDVKNFWQGVKSKVTALC--WHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISS 466
T ++ N +++K C + P+ LAFG D V YD + K P +
Sbjct: 543 T-------NLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVF 595
Query: 467 TYHKKTV 473
H+K V
Sbjct: 596 KGHRKAV 602
Score = 40.8 bits (94), Expect = 0.010
Identities = 43/205 (20%), Positives = 83/205 (40%), Gaps = 17/205 (8%)
Query: 80 NLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWF 139
NL A+S +GTV +WD T + H+ ++ ++ L+ SG + V +
Sbjct: 484 NLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWST 543
Query: 140 NRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIH 199
N ++S + C+ SP +A G D V D+ + I +GH +
Sbjct: 544 NLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVS 603
Query: 200 SIAWCPLPGEDCLSINQEE-------------TSEEAEITNGNAVAQAPVTKGCYLATGS 246
+ + GE+ +S + + S + I N V A + G Y+A GS
Sbjct: 604 YAKF--VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLA--SNGDYIACGS 659
Query: 247 KDQTIRIWSCSRGRGVMILKLPFLK 271
++ ++ ++ + ++ K +K
Sbjct: 660 ENNSLYLYYKGLSKTLLTFKFDTVK 684
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 55.8 bits (133), Expect = 3e-07
Identities = 33/119 (27%), Positives = 61/119 (51%), Gaps = 5/119 (4%)
Query: 609 IYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWD 668
I V+ TVI+ + V I P ++ ++ KI+ ++WS +H L S+ Y+GT +WD
Sbjct: 421 IKVYEYDTVIQDA----VDIHYPENEMTCNS-KISCISWSSYHKNLLASSDYEGTVILWD 475
Query: 669 ALREEPLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQGKKSI 727
+ ++ H R V ++ +DP + SG+DD V W T++ + + K ++
Sbjct: 476 GFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANV 534
Score = 43.9 bits (102), Expect = 0.001
Identities = 35/127 (27%), Positives = 56/127 (44%), Gaps = 9/127 (7%)
Query: 349 KQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAFSSVDIGSLAIGVGDGMIRVWN 408
K LL S+ + V WD T + S +S+ F+ +D LA G D +++W+
Sbjct: 459 KNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWS 518
Query: 409 TLSIKNNYDVKNFWQGVKSKVTALC--WHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISS 466
T ++ N +++K C + P+ LAFG D V YD + K P +
Sbjct: 519 T-------NLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVF 571
Query: 467 TYHKKTV 473
H+K V
Sbjct: 572 KGHRKAV 578
Score = 40.8 bits (94), Expect = 0.010
Identities = 43/205 (20%), Positives = 83/205 (40%), Gaps = 17/205 (8%)
Query: 80 NLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWF 139
NL A+S +GTV +WD T + H+ ++ ++ L+ SG + V +
Sbjct: 460 NLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWST 519
Query: 140 NRNDSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIH 199
N ++S + C+ SP +A G D V D+ + I +GH +
Sbjct: 520 NLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVS 579
Query: 200 SIAWCPLPGEDCLSINQEE-------------TSEEAEITNGNAVAQAPVTKGCYLATGS 246
+ + GE+ +S + + S + I N V A + G Y+A GS
Sbjct: 580 YAKF--VSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLA--SNGDYIACGS 635
Query: 247 KDQTIRIWSCSRGRGVMILKLPFLK 271
++ ++ ++ + ++ K +K
Sbjct: 636 ENNSLYLYYKGLSKTLLTFKFDTVK 660
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 55.8 bits (133), Expect = 3e-07
Identities = 51/213 (23%), Positives = 92/213 (43%), Gaps = 36/213 (16%)
Query: 74 HHPGQYNLC----ATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGD 129
HHP ++ AT +DG +KIW+V+T ++ + HQ + L ++P ++VS
Sbjct: 114 HHPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSAS 173
Query: 130 EKGVVFCYWFNRNDSQHLFIEP--RTIFCLTCSPHHEDLV-AIGYKDGIVVIIDISKKGE 186
+ + N++ Q + + ++C + SP L A G K V + +
Sbjct: 174 RDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKS---VFLWSMRSYT 230
Query: 187 VIHRLRGHDDEIHS-------------------IAWCPLPGEDCLSINQEET-----SEE 222
+I +L GH + S I W P GE S++ + +
Sbjct: 231 LIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSD 290
Query: 223 AEITNGNAVAQAPVTKGCYLATGSKDQTIRIWS 255
I++ +V +P +G YLAT + D+ +RIW+
Sbjct: 291 VHISSLRSVCFSP--EGLYLATVADDRLLRIWA 321
Score = 40.4 bits (93), Expect = 0.013
Identities = 37/143 (25%), Positives = 62/143 (43%), Gaps = 15/143 (10%)
Query: 586 WHHEHGSQPELSYL-MASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITS 644
W H P++S L +A+G N+ I + ++T + LSGH +
Sbjct: 111 WARHHPQVPDVSCLVLATGLNDGQIKIWEVQTGLL------------LLNLSGHQDVVRD 158
Query: 645 VAWSPHHDGRLVSASYDGTAQVWDALRE-EPLCNFRGHRGRLLCVAWSPLDPDCIYSGAD 703
++++P LVSAS D T ++WD + + + GH + C + SP D + S A
Sbjct: 159 LSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISP-DCSMLCSAAG 217
Query: 704 DFCVHKWLTSMQDHSRPPQGKKS 726
+ V W R +G +S
Sbjct: 218 EKSVFLWSMRSYTLIRKLEGHQS 240
Score = 36.2 bits (82), Expect = 0.25
Identities = 73/318 (22%), Positives = 111/318 (34%), Gaps = 85/318 (26%)
Query: 166 LVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCPLPGEDCLSINQEETSEEAEI 225
++A G DG + I ++ + G ++ L GH D + +++ P
Sbjct: 125 VLATGLNDGQIKIWEV-QTGLLLLNLSGHQDVVRDLSFTP-------------------- 163
Query: 226 TNGNAVAQAPVTKGCYLATGSKDQTIRIWSCSRGRGVMILKLPFLKRRGGGIDPTVKERL 285
+G+ + L + S+D+T+RIW L + G I
Sbjct: 164 -SGSLI----------LVSASRDKTLRIWD--------------LNKHGKQIQVLSGHLQ 198
Query: 286 WLTLHWPSNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSASSEGQNHSRIVFNLCPLQT 345
W+ S + L S+ + W + R YTL EG S + + P
Sbjct: 199 WVYCCSISPDCSMLCSAAGEKSVFLWSM-----RSYTLI-RKLEGHQSSVVSCDFSP--- 249
Query: 346 EDDKQLLLSTSMDRDVKCWDIATLECSWTLPSLGGFAYSLAF--SSVDIGS--------- 394
D LL++ S D +V WD T E L SL A S V I S
Sbjct: 250 --DSALLVTASYDTNVIMWDPYTGE---RLRSLHHTQVDPAMDDSDVHISSLRSVCFSPE 304
Query: 395 ---LAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKV 451
LA D ++R+W L +K G+ C G +A GT DG V
Sbjct: 305 GLYLATVADDRLLRIW-ALELKTPIAFAPMTNGL------CCTFFPHGGVIATGTRDGHV 357
Query: 452 GLYDTYSNKPPQISSTYH 469
+ P +SS H
Sbjct: 358 QFW----TAPRVLSSLKH 371
Score = 34.7 bits (78), Expect = 0.72
Identities = 34/157 (21%), Positives = 59/157 (37%), Gaps = 38/157 (24%)
Query: 550 IMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAVI 609
++A G DG I+I+++ L+ + H +V +S+ P S ++ S S + +
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSF------TPSGSLILVSASRDKTL 178
Query: 610 YVHNLKT----------------VIESSPESPVTITEP---------------YRTLSGH 638
+ +L SP+ + + R L GH
Sbjct: 179 RIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGH 238
Query: 639 TAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPL 675
+ + S +SP LV+ASYD +WD E L
Sbjct: 239 QSSVVSCDFSPD-SALLVTASYDTNVIMWDPYTGERL 274
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 55.5 bits (132), Expect = 4e-07
Identities = 62/264 (23%), Positives = 102/264 (38%), Gaps = 54/264 (20%)
Query: 423 QGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPV 482
+G + + L W+P G L +DD + L+D + P+ KT++T
Sbjct: 139 RGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDI--SAVPKEGKVVDAKTIFT------- 189
Query: 483 PPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGE------AFDINKLIRDTNSIKYKL 536
G V++ W L E A D +I DT S
Sbjct: 190 --------------------GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSK 229
Query: 537 PVHTEISWKADGK----------IMALGNEDGSIEIFQIPNLKL-ICTIQQHHKLVNTIS 585
P H+ + A+ I+A G+ D ++ ++ + NLKL + + + H + +
Sbjct: 230 PSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQ 289
Query: 586 WHHEHGSQPELSYLMASGSNNAVIYVHNLKTV-IESSPESPVT-ITEPYRTLSGHTAKIT 643
W P ++AS + + V +L + E SPE E GHTAKI+
Sbjct: 290 W------SPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKIS 343
Query: 644 SVAWSPHHDGRLVSASYDGTAQVW 667
+W+P+ + S S D QVW
Sbjct: 344 DFSWNPNEPWVICSVSEDNIMQVW 367
Score = 54.7 bits (130), Expect = 7e-07
Identities = 47/193 (24%), Positives = 80/193 (41%), Gaps = 33/193 (17%)
Query: 60 LVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWD----------VETKTVVTEHALHQ 109
L GH + G+ S +P ++SDD T+ +WD V+ KT+ T H
Sbjct: 138 LRGHQKE--GYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTA-- 193
Query: 110 HTISTLHWSPRVKDLI--VSGDEKGVVFCYWFNRNDSQHLFIEPRT--IFCLTCSPHHED 165
+ + W + L V+ D+K +++ N ++ T + CL+ +P+ E
Sbjct: 194 -VVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEF 252
Query: 166 LVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCP--------------LPGEDC 211
++A G D V + D+ +H H DEI + W P L D
Sbjct: 253 ILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDL 312
Query: 212 LSINQEETSEEAE 224
I +E++ E+AE
Sbjct: 313 SKIGEEQSPEDAE 325
Score = 48.5 bits (114), Expect = 5e-05
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 16/147 (10%)
Query: 577 HHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLS 636
H +V +SWH H S L S +++ + + + ++ S P V
Sbjct: 191 HTAVVEDVSWHLLHES------LFGSVADDQKLMIWDTRSNNTSKPSHSV---------D 235
Query: 637 GHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALR-EEPLCNFRGHRGRLLCVAWSPLDP 695
HTA++ ++++P+ + L + S D T +WD + L +F H+ + V WSP +
Sbjct: 236 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 295
Query: 696 DCIYSGADDFCVHKWLTSMQDHSRPPQ 722
+ S D ++ W S + P+
Sbjct: 296 TILASSGTDRRLNVWDLSKIGEEQSPE 322
Score = 41.6 bits (96), Expect = 0.006
Identities = 33/107 (30%), Positives = 47/107 (43%), Gaps = 7/107 (6%)
Query: 621 SPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWD--ALREE----- 673
S P P L GH + ++W+P+ G L+SAS D T +WD A+ +E
Sbjct: 124 SKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVD 183
Query: 674 PLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRP 720
F GH + V+W L S ADD + W T + S+P
Sbjct: 184 AKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKP 230
Score = 36.2 bits (82), Expect = 0.25
Identities = 35/140 (25%), Positives = 58/140 (41%), Gaps = 16/140 (11%)
Query: 352 LLSTSMDRDVKCWDIATLECSWTLPS-----------LGGFAYSLAFSSVDIGSLAIGVG 400
LLS S D + WDI+ + + + ++ L S+ GS+A
Sbjct: 158 LLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESL-FGSVA---D 213
Query: 401 DGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNK 460
D + +W+T S N + ++V L ++P E LA G+ D V L+D + K
Sbjct: 214 DQKLMIWDTRS-NNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLK 272
Query: 461 PPQISSTYHKKTVYTLAWGP 480
S HK ++ + W P
Sbjct: 273 LKLHSFESHKDEIFQVQWSP 292
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 55.5 bits (132), Expect = 4e-07
Identities = 62/264 (23%), Positives = 102/264 (38%), Gaps = 54/264 (20%)
Query: 423 QGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPV 482
+G + + L W+P G L +DD + L+D + P+ KT++T
Sbjct: 173 RGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDI--SAVPKEGKVVDAKTIFT------- 223
Query: 483 PPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGE------AFDINKLIRDTNSIKYKL 536
G V++ W L E A D +I DT S
Sbjct: 224 --------------------GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSK 263
Query: 537 PVHTEISWKADGK----------IMALGNEDGSIEIFQIPNLKL-ICTIQQHHKLVNTIS 585
P H+ + A+ I+A G+ D ++ ++ + NLKL + + + H + +
Sbjct: 264 PSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQ 323
Query: 586 WHHEHGSQPELSYLMASGSNNAVIYVHNLKTV-IESSPESPVT-ITEPYRTLSGHTAKIT 643
W P ++AS + + V +L + E SPE E GHTAKI+
Sbjct: 324 W------SPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKIS 377
Query: 644 SVAWSPHHDGRLVSASYDGTAQVW 667
+W+P+ + S S D QVW
Sbjct: 378 DFSWNPNEPWVICSVSEDNIMQVW 401
Score = 54.7 bits (130), Expect = 7e-07
Identities = 47/193 (24%), Positives = 80/193 (41%), Gaps = 33/193 (17%)
Query: 60 LVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWD----------VETKTVVTEHALHQ 109
L GH + G+ S +P ++SDD T+ +WD V+ KT+ T H
Sbjct: 172 LRGHQKE--GYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTA-- 227
Query: 110 HTISTLHWSPRVKDLI--VSGDEKGVVFCYWFNRNDSQHLFIEPRT--IFCLTCSPHHED 165
+ + W + L V+ D+K +++ N ++ T + CL+ +P+ E
Sbjct: 228 -VVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEF 286
Query: 166 LVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCP--------------LPGEDC 211
++A G D V + D+ +H H DEI + W P L D
Sbjct: 287 ILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDL 346
Query: 212 LSINQEETSEEAE 224
I +E++ E+AE
Sbjct: 347 SKIGEEQSPEDAE 359
Score = 48.5 bits (114), Expect = 5e-05
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 16/147 (10%)
Query: 577 HHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLS 636
H +V +SWH H S L S +++ + + + ++ S P V
Sbjct: 225 HTAVVEDVSWHLLHES------LFGSVADDQKLMIWDTRSNNTSKPSHSV---------D 269
Query: 637 GHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALR-EEPLCNFRGHRGRLLCVAWSPLDP 695
HTA++ ++++P+ + L + S D T +WD + L +F H+ + V WSP +
Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 329
Query: 696 DCIYSGADDFCVHKWLTSMQDHSRPPQ 722
+ S D ++ W S + P+
Sbjct: 330 TILASSGTDRRLNVWDLSKIGEEQSPE 356
Score = 41.6 bits (96), Expect = 0.006
Identities = 33/107 (30%), Positives = 47/107 (43%), Gaps = 7/107 (6%)
Query: 621 SPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWD--ALREE----- 673
S P P L GH + ++W+P+ G L+SAS D T +WD A+ +E
Sbjct: 158 SKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVD 217
Query: 674 PLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRP 720
F GH + V+W L S ADD + W T + S+P
Sbjct: 218 AKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKP 264
Score = 36.2 bits (82), Expect = 0.25
Identities = 35/140 (25%), Positives = 58/140 (41%), Gaps = 16/140 (11%)
Query: 352 LLSTSMDRDVKCWDIATLECSWTLPS-----------LGGFAYSLAFSSVDIGSLAIGVG 400
LLS S D + WDI+ + + + ++ L S+ GS+A
Sbjct: 192 LLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESL-FGSVA---D 247
Query: 401 DGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNK 460
D + +W+T S N + ++V L ++P E LA G+ D V L+D + K
Sbjct: 248 DQKLMIWDTRS-NNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLK 306
Query: 461 PPQISSTYHKKTVYTLAWGP 480
S HK ++ + W P
Sbjct: 307 LKLHSFESHKDEIFQVQWSP 326
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 55.5 bits (132), Expect = 4e-07
Identities = 62/264 (23%), Positives = 102/264 (38%), Gaps = 54/264 (20%)
Query: 423 QGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLAWGPPV 482
+G + + L W+P G L +DD + L+D + P+ KT++T
Sbjct: 174 RGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDI--SAVPKEGKVVDAKTIFT------- 224
Query: 483 PPMSLGGEGDRPSLALYSCGGEGIVLQHNPWKLSGE------AFDINKLIRDTNSIKYKL 536
G V++ W L E A D +I DT S
Sbjct: 225 --------------------GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSK 264
Query: 537 PVHTEISWKADGK----------IMALGNEDGSIEIFQIPNLKL-ICTIQQHHKLVNTIS 585
P H+ + A+ I+A G+ D ++ ++ + NLKL + + + H + +
Sbjct: 265 PSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQ 324
Query: 586 WHHEHGSQPELSYLMASGSNNAVIYVHNLKTV-IESSPESPVT-ITEPYRTLSGHTAKIT 643
W P ++AS + + V +L + E SPE E GHTAKI+
Sbjct: 325 W------SPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKIS 378
Query: 644 SVAWSPHHDGRLVSASYDGTAQVW 667
+W+P+ + S S D QVW
Sbjct: 379 DFSWNPNEPWVICSVSEDNIMQVW 402
Score = 54.7 bits (130), Expect = 7e-07
Identities = 47/193 (24%), Positives = 80/193 (41%), Gaps = 33/193 (17%)
Query: 60 LVGHTERVSGFTFSHHPGQYNLCATSSDDGTVKIWD----------VETKTVVTEHALHQ 109
L GH + G+ S +P ++SDD T+ +WD V+ KT+ T H
Sbjct: 173 LRGHQKE--GYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTA-- 228
Query: 110 HTISTLHWSPRVKDLI--VSGDEKGVVFCYWFNRNDSQHLFIEPRT--IFCLTCSPHHED 165
+ + W + L V+ D+K +++ N ++ T + CL+ +P+ E
Sbjct: 229 -VVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEF 287
Query: 166 LVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCP--------------LPGEDC 211
++A G D V + D+ +H H DEI + W P L D
Sbjct: 288 ILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDL 347
Query: 212 LSINQEETSEEAE 224
I +E++ E+AE
Sbjct: 348 SKIGEEQSPEDAE 360
Score = 48.5 bits (114), Expect = 5e-05
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 16/147 (10%)
Query: 577 HHKLVNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLS 636
H +V +SWH H S L S +++ + + + ++ S P V
Sbjct: 226 HTAVVEDVSWHLLHES------LFGSVADDQKLMIWDTRSNNTSKPSHSV---------D 270
Query: 637 GHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALR-EEPLCNFRGHRGRLLCVAWSPLDP 695
HTA++ ++++P+ + L + S D T +WD + L +F H+ + V WSP +
Sbjct: 271 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 330
Query: 696 DCIYSGADDFCVHKWLTSMQDHSRPPQ 722
+ S D ++ W S + P+
Sbjct: 331 TILASSGTDRRLNVWDLSKIGEEQSPE 357
Score = 41.6 bits (96), Expect = 0.006
Identities = 33/107 (30%), Positives = 47/107 (43%), Gaps = 7/107 (6%)
Query: 621 SPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWD--ALREE----- 673
S P P L GH + ++W+P+ G L+SAS D T +WD A+ +E
Sbjct: 159 SKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVD 218
Query: 674 PLCNFRGHRGRLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRP 720
F GH + V+W L S ADD + W T + S+P
Sbjct: 219 AKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKP 265
Score = 36.2 bits (82), Expect = 0.25
Identities = 35/140 (25%), Positives = 58/140 (41%), Gaps = 16/140 (11%)
Query: 352 LLSTSMDRDVKCWDIATLECSWTLPS-----------LGGFAYSLAFSSVDIGSLAIGVG 400
LLS S D + WDI+ + + + ++ L S+ GS+A
Sbjct: 193 LLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESL-FGSVA---D 248
Query: 401 DGMIRVWNTLSIKNNYDVKNFWQGVKSKVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNK 460
D + +W+T S N + ++V L ++P E LA G+ D V L+D + K
Sbjct: 249 DQKLMIWDTRS-NNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLK 307
Query: 461 PPQISSTYHKKTVYTLAWGP 480
S HK ++ + W P
Sbjct: 308 LKLHSFESHKDEIFQVQWSP 327
>gi|89886480 zinedin isoform 2 [Homo sapiens]
Length = 760
Score = 54.7 bits (130), Expect = 7e-07
Identities = 35/91 (38%), Positives = 45/91 (49%), Gaps = 13/91 (14%)
Query: 631 PYRTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWD-----------ALREEPLCNFR 679
P TL H I S+A+ H L++AS DGT ++W+ AL EP+ FR
Sbjct: 437 PKFTLRSHYDGIRSLAFH-HSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFR 495
Query: 680 GHRGRLLCVAWSPLDPDCIYSGADDFCVHKW 710
HRG +L VA C YSG D C+H W
Sbjct: 496 AHRGPVLAVAMGSNSEYC-YSGGADACIHSW 525
Score = 41.6 bits (96), Expect = 0.006
Identities = 46/176 (26%), Positives = 75/176 (42%), Gaps = 22/176 (12%)
Query: 515 LSGEAFDINKLIRDTNSIKYKLPVHTE----ISWKADGKIMALGNEDGSIEIFQIPNLKL 570
LS + D + T + K+ L H + +++ + +EDG+++++ NL+
Sbjct: 420 LSCDLSDSKDAFKKTWNPKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKLW---NLQK 476
Query: 571 ICTIQQHHKL-VNTISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTIT 629
T +++ L V I H P L+ +A GSN+ Y I S + P
Sbjct: 477 AVTAKKNAALDVEPIHAFRAHRG-PVLA--VAMGSNSEYCYSGGADACIHSW-KIPDLSM 532
Query: 630 EPY---------RTLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLC 676
+PY L GH + +A+SP RL S S DGT ++WD P C
Sbjct: 533 DPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQ-RLASCSADGTVRIWDPSSSSPAC 587
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,936,663
Number of Sequences: 37866
Number of extensions: 3113640
Number of successful extensions: 14283
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 250
Number of HSP's that attempted gapping in prelim test: 11451
Number of HSP's gapped (non-prelim): 2500
length of query: 1508
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1393
effective length of database: 13,892,928
effective search space: 19352848704
effective search space used: 19352848704
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.