Search of human proteins with 157738645

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157738645 plexin A4 isoform 1 [Homo sapiens]
         (1894 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157738645 plexin A4 isoform 1 [Homo sapiens]                      3848   0.0  
gi|113722116 plexin A2 [Homo sapiens]                                2613   0.0  
gi|49355818 plexin A1 [Homo sapiens]                                 2442   0.0  
gi|59710104 plexin A3 [Homo sapiens]                                 2306   0.0  
gi|149363636 plexin B2 [Homo sapiens]                                 936   0.0  
gi|157738643 plexin A4 isoform 2 [Homo sapiens]                       932   0.0  
gi|157738647 plexin A4 isoform 3 [Homo sapiens]                       927   0.0  
gi|253795481 plexin B3 isoform 2 [Homo sapiens]                       927   0.0  
gi|29336063 plexin B3 isoform 1 [Homo sapiens]                        927   0.0  
gi|157694524 plexin D1 [Homo sapiens]                                 887   0.0  
gi|194272180 plexin B1 [Homo sapiens]                                 793   0.0  
gi|40254442 plexin B1 [Homo sapiens]                                  793   0.0  
gi|5032223 plexin C1 [Homo sapiens]                                   423   e-118
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]     156   2e-37
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]    156   2e-37
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s...   103   2e-21
gi|39777610 semaphorin 4B precursor [Homo sapiens]                     91   8e-18
gi|39777608 semaphorin 4B precursor [Homo sapiens]                     91   8e-18
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]                     77   2e-13
gi|147904700 semaphorin 5A [Homo sapiens]                              74   1e-12
gi|21361914 semaphorin B [Homo sapiens]                                72   5e-12
gi|126116589 fibrocystin L [Homo sapiens]                              68   7e-11
gi|157388902 semaphorin 4C [Homo sapiens]                              60   2e-08
gi|19718780 semaphorin 6B precursor [Homo sapiens]                     60   3e-08
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]           57   1e-07
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]           57   1e-07
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]           57   1e-07
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]           57   1e-07
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]           57   1e-07
gi|188497703 semaphorin 3F [Homo sapiens]                              54   1e-06

>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
          Length = 1894

 Score = 3848 bits (9979), Expect = 0.0
 Identities = 1894/1894 (100%), Positives = 1894/1894 (100%)

Query: 1    MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
            MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT
Sbjct: 1    MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60

Query: 61   GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
            GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI
Sbjct: 61   GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120

Query: 121  DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
            DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD
Sbjct: 121  DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180

Query: 181  DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
            DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF
Sbjct: 181  DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240

Query: 241  DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
            DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC
Sbjct: 241  DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300

Query: 301  ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
            ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL
Sbjct: 301  ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360

Query: 361  KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
            KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR
Sbjct: 361  KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420

Query: 421  GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGP 480
            GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGP
Sbjct: 421  GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGP 480

Query: 481  VLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKE 540
            VLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKE
Sbjct: 481  VLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKE 540

Query: 541  RCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETYNVPELSAGVNCTFEDLSE 600
            RCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETYNVPELSAGVNCTFEDLSE
Sbjct: 541  RCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETYNVPELSAGVNCTFEDLSE 600

Query: 601  MDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMTFASTSFVFYNCSVHN 660
            MDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMTFASTSFVFYNCSVHN
Sbjct: 601  MDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMTFASTSFVFYNCSVHN 660

Query: 661  SCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCPQLLRVDKILVPVEVIKPI 720
            SCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCPQLLRVDKILVPVEVIKPI
Sbjct: 661  SCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCPQLLRVDKILVPVEVIKPI 720

Query: 721  TLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQCQNTSYSYEGMEINNLPVE 780
            TLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQCQNTSYSYEGMEINNLPVE
Sbjct: 721  TLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQCQNTSYSYEGMEINNLPVE 780

Query: 781  LTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFACGWCQGPGQCTLRQHCPA 840
            LTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFACGWCQGPGQCTLRQHCPA
Sbjct: 781  LTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFACGWCQGPGQCTLRQHCPA 840

Query: 841  QESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVE 900
            QESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVE
Sbjct: 841  QESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVE 900

Query: 901  CSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLK 960
            CSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLK
Sbjct: 901  CSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLK 960

Query: 961  PSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPSYIVCNTTSSDEVLEMKVS 1020
            PSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPSYIVCNTTSSDEVLEMKVS
Sbjct: 961  PSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPSYIVCNTTSSDEVLEMKVS 1020

Query: 1021 VQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIRAKHGGK 1080
            VQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIRAKHGGK
Sbjct: 1021 VQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIRAKHGGK 1080

Query: 1081 EHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQSLLILNKTNFTYYP 1140
            EHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQSLLILNKTNFTYYP
Sbjct: 1081 EHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQSLLILNKTNFTYYP 1140

Query: 1141 NPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKPCTVTVSDVQLL 1200
            NPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKPCTVTVSDVQLL
Sbjct: 1141 NPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKPCTVTVSDVQLL 1200

Query: 1201 CESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSIAVAGGLLIIFIVAVLIAY 1260
            CESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSIAVAGGLLIIFIVAVLIAY
Sbjct: 1201 CESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSIAVAGGLLIIFIVAVLIAY 1260

Query: 1261 KRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHELTSDLDGAGIPFLDYRTY 1320
            KRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHELTSDLDGAGIPFLDYRTY
Sbjct: 1261 KRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHELTSDLDGAGIPFLDYRTY 1320

Query: 1321 TMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNKVFLLSFIRTLESQRSFSM 1380
            TMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNKVFLLSFIRTLESQRSFSM
Sbjct: 1321 TMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNKVFLLSFIRTLESQRSFSM 1380

Query: 1381 RDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNHPKLLLRRTESVAEKMLTN 1440
            RDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNHPKLLLRRTESVAEKMLTN
Sbjct: 1381 RDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNHPKLLLRRTESVAEKMLTN 1440

Query: 1441 WFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTL 1500
            WFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTL
Sbjct: 1441 WFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTL 1500

Query: 1501 VLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQGSG 1560
            VLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQGSG
Sbjct: 1501 VLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQGSG 1560

Query: 1561 ARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQVTAYNAVNNSTVSRTSASK 1620
            ARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQVTAYNAVNNSTVSRTSASK
Sbjct: 1561 ARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQVTAYNAVNNSTVSRTSASK 1620

Query: 1621 YENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGDQKEGDRGSKMVSEIYLTR 1680
            YENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGDQKEGDRGSKMVSEIYLTR
Sbjct: 1621 YENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGDQKEGDRGSKMVSEIYLTR 1680

Query: 1681 LLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKS 1740
            LLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKS
Sbjct: 1681 LLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKS 1740

Query: 1741 NCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLY 1800
            NCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLY
Sbjct: 1741 NCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLY 1800

Query: 1801 AKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKY 1860
            AKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKY
Sbjct: 1801 AKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKY 1860

Query: 1861 SEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1894
            SEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS
Sbjct: 1861 SEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1894


>gi|113722116 plexin A2 [Homo sapiens]
          Length = 1894

 Score = 2613 bits (6773), Expect = 0.0
 Identities = 1271/1870 (67%), Positives = 1509/1870 (80%), Gaps = 10/1870 (0%)

Query: 31   APLSQKQRSFVTFRGEPAEG-FNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPD 89
            AP +     F TF  E  +  FNHL V + TG +Y+GA+NR+YKL+ +L + V H+TGP+
Sbjct: 29   APPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQVAHKTGPE 88

Query: 90   EDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKL 149
            EDN  CYPP IVQ C+E LT TNNVNK+L+IDY ENRL+ACGSLYQG+CKLLRL+DLF L
Sbjct: 89   EDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLFIL 148

Query: 150  GEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSE 209
             EP HKKEHYLS VN++G+++GVIV     D KLFI TAVDGK +YFPT+SSRKL ++ E
Sbjct: 149  VEPSHKKEHYLSSVNKTGTMYGVIVRSEGEDGKLFIGTAVDGKQDYFPTLSSRKLPRDPE 208

Query: 210  ADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPG- 268
            +  M  Y  H +FV+S+IKIPSDT  ++  FDI+Y+YGF+SG FVYFLT+QPE  +P G 
Sbjct: 209  SSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPE--TPEGV 266

Query: 269  --STTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTL 326
              ++  +  YTS++VRLCK+D  F+SYV +P GC R+GVEYRLLQAAYL+K G  L +  
Sbjct: 267  AINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLAKPGDSLAQAF 326

Query: 327  GVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWL 386
             +   DD+LF +FSKGQK+     D+SALC F ++ IN +IKERLQSCY+GEG L+L WL
Sbjct: 327  NITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQGEGNLELNWL 386

Query: 387  KVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLA 446
              KD+ C+ A + IDDNFCGLD+N PLG S  V G+ ++T  RDRMTSV +YVY  +S+ 
Sbjct: 387  LGKDVQCTKAPVPIDDNFCGLDINQPLGGSTPVEGLTLYTTSRDRMTSVASYVYNGYSVV 446

Query: 447  FVGTKSGKLKKIRVDGPRGNALQYETVQVVDPG-PVLRDMAFSKDHEQLYIMSERQLTRV 505
            FVGTKSGKLKKIR DGP    +QYE V V+  G P+LRDMAFS D   LY+MSERQ+TRV
Sbjct: 447  FVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFSIDQRYLYVMSERQVTRV 506

Query: 506  PVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHP 565
            PVESC QY +CGECL SGDPHCGWC LHN C+R+++C+++ EP RFA+ + QCV L VHP
Sbjct: 507  PVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEPNRFAASISQCVSLAVHP 566

Query: 566  NNISVSQYNVLLVLETYNVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIIT 625
            ++ISVS+++ LL L   + P+LSAG+ C F +L+E++G V G+Q+ C SP  K+VP +I 
Sbjct: 567  SSISVSEHSRLLSLVVSDAPDLSAGIACAFGNLTEVEGQVSGSQVICISPGPKDVP-VIP 625

Query: 626  ENGDHHVVQLQLKSKETGMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDP 685
             + D   ++LQL+SKETG  F ST F FYNCS H  CLSCV S +RCHWCKYR++CTHDP
Sbjct: 626  LDQDWFGLELQLRSKETGKIFVSTEFKFYNCSAHQLCLSCVNSAFRCHWCKYRNLCTHDP 685

Query: 686  KTCSFQEGRVKLPEDCPQLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQG 745
             TCSFQEGR+ + EDCPQL+  ++IL+PV  +KPITLKA+NLPQPQSGQRGYEC+LNIQG
Sbjct: 686  TTCSFQEGRINISEDCPQLVPTEEILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQG 745

Query: 746  SEQRVPALRFNSSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCG 805
            +  RVPALRFNSSSVQCQN+SY Y+GM+I+NL V+  VVWNG+F IDNP   KVHLYKC 
Sbjct: 746  AIHRVPALRFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCA 805

Query: 806  AMRESCGLCLKADPDFACGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIP 865
            A RESCGLCLKAD  F CGWC G  +CTL QHC +  S WL+ S    KC+NP+ITEI+ 
Sbjct: 806  AQRESCGLCLKADRKFECGWCSGERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILT 865

Query: 866  VTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQ 925
            V+GP EGGT+VTI G NLGL+F +IA HV+VAGV C+PL   YI AEQIVCEMG A    
Sbjct: 866  VSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVGT 925

Query: 926  HAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNV 985
             +G V +C+  C+PEFM +S Q Y F+  ++  L P RGP SGGT VTITG  L AGS+V
Sbjct: 926  TSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSV 985

Query: 986  VVMFGKQPCLFHRRSPSYIVC-NTTSSDEVLEMKVSVQVDRAKIHQDLVFQYVEDPTIVR 1044
             V  G Q C F+ RS S IVC +  SS+ +  + VSV VDRA +  +L F+Y++DP + R
Sbjct: 986  AVYLGNQTCEFYGRSMSEIVCVSPPSSNGLGPVPVSVSVDRAHVDSNLQFEYIDDPRVQR 1045

Query: 1045 IEPEWSIVSGNTPIAVWGTHLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALG 1104
            IEPEWSI SG+TP+ + G +LD+IQ P+IR K  GKE +N+C+V+N T +TC AP+L   
Sbjct: 1046 IEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNGKESVNVCKVVNTTTLTCLAPSLTTD 1105

Query: 1105 PDHQSDLTERPEEFGFILDNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILK 1164
                 D  ERP+EFGF+ +NVQSLLI N T F YYPNP FE   P+G+L+ KPG+PIILK
Sbjct: 1106 YRPGLDTVERPDEFGFVFNNVQSLLIYNDTKFIYYPNPTFELLSPTGVLDQKPGSPIILK 1165

Query: 1165 GKNLIPPVAGGNVKLNYTVLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPG 1224
            GKNL PP +GG  KLNYTVL+GE PC VTVS+ QLLCE PNL G+HKVM  VGGM +SPG
Sbjct: 1166 GKNLCPPASGG-AKLNYTVLIGETPCAVTVSETQLLCEPPNLTGQHKVMVHVGGMVFSPG 1224

Query: 1225 MVYIAPDSPLSLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESR 1284
             V +  DS L+LPAIVSIA  G LL+I ++ VLIAYKRKSRE+DLTLKRLQMQMDNLESR
Sbjct: 1225 SVSVISDSLLTLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESR 1284

Query: 1285 VALECKEAFAELQTDIHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYR 1344
            VALECKEAFAELQTDI+ELTSDLD +GIP+LDYRTY MRVLFPGIEDHPVLR+LEV G  
Sbjct: 1285 VALECKEAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNG 1344

Query: 1345 QERVEKGLKLFAQLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDV 1404
            Q+ VEK LKLFAQLINNKVFLL+FIRTLE QRSFSMRDRGNVASLIMT LQ +LEYATDV
Sbjct: 1345 QQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDV 1404

Query: 1405 LKQLLADLIDKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCA 1464
            LKQLL+DLIDKNLE+KNHPKLLLRRTESVAEKMLTNWF FLL+KFLKECAGEPLF L+CA
Sbjct: 1405 LKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCA 1464

Query: 1465 IKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDT 1524
            IKQQMEKGPIDAITGEARYSLSEDKLIRQQI+YKTL+L+CV+PDN NSPE+PVK+LNCDT
Sbjct: 1465 IKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLILNCVNPDNENSPEIPVKVLNCDT 1524

Query: 1525 ITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTL 1584
            ITQVKEKILDA++KNVP S RP+A DMDLEWRQG  AR++LQDEDITTKIE DWKRLNTL
Sbjct: 1525 ITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTL 1584

Query: 1585 AHYQVPDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPD 1644
             HYQV D SVVALV KQ ++YN   ++++SRTS S+Y++  RYTGSPDSLRSR PMITPD
Sbjct: 1585 MHYQVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPD 1644

Query: 1645 LESGVKMWHLVKNHEHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAH 1704
            LESGVK+WHLVKNH+HGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFET+FST H
Sbjct: 1645 LESGVKVWHLVKNHDHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETLFSTVH 1704

Query: 1705 RGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKN 1764
            RGSALPLAIKYMFDFLDEQAD+H IHD  VRHTWKSNCLPLRFWVN+IKNPQFVFDIHK 
Sbjct: 1705 RGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKG 1764

Query: 1765 SITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAI 1824
            SITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYK+WVERYY+DI K+PAI
Sbjct: 1765 SITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADIAKLPAI 1824

Query: 1825 SDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLE 1884
            SDQDMNAYLAEQSR+H  EFN +SAL+EI+SYV KYSEE++G L+ D+Q  +Q+LAYK+E
Sbjct: 1825 SDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQRLAYKVE 1884

Query: 1885 QVITLMSLDS 1894
            Q+I  MS++S
Sbjct: 1885 QLINAMSIES 1894


>gi|49355818 plexin A1 [Homo sapiens]
          Length = 1873

 Score = 2442 bits (6330), Expect = 0.0
 Identities = 1199/1853 (64%), Positives = 1454/1853 (78%), Gaps = 14/1853 (0%)

Query: 50   GFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLT 109
            G  HLVV E+TG +Y+GAVNRIYKLS +L +L  H TGP EDN KCYPP  VQ+C   L 
Sbjct: 27   GLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQSCPHGLG 86

Query: 110  TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
            +T+NVNK+LL+DY  NRL+ACGS  QGIC+ LRL+DLFKLGEP+H+KEHYLS V E+GS+
Sbjct: 87   STDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSM 146

Query: 170  FGVIVSY--SNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMI 227
             GV+++        KLF+ T +DGK EYFPT+SSR+L  N E   MF +V+ DEFV+S +
Sbjct: 147  AGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFGFVYQDEFVSSQL 206

Query: 228  KIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKED 287
            KIPSDT +  P FDIYYVY F S  FVY+LTLQ +          E  +TSK+VRLC +D
Sbjct: 207  KIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTSKIVRLCVDD 266

Query: 288  TAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKM 347
              F SYVE PIGCE++GVEYRL+Q AYLS+ G  L   LG+  D+D+LFTVF++GQK ++
Sbjct: 267  PKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRV 326

Query: 348  KSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGL 407
            K   ESALC+F L+ I ++IKER+QSCYRGEG L L WL  K++ C ++ L IDD+FCG 
Sbjct: 327  KPPKESALCLFTLRAIKEKIKERIQSCYRGEGKLSLPWLLNKELGCINSPLQIDDDFCGQ 386

Query: 408  DMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVD--GPRG 465
            D N PLG +  + G P+F +  D +T+V AY Y+  ++ F GT+SG+++KI VD   P G
Sbjct: 387  DFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRKILVDLSNPGG 446

Query: 466  N-ALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGD 524
              AL YE+V   +  P+LRD+  S +H+ LY M+E+Q+TRVPVESC QY SC  CLGS D
Sbjct: 447  RPALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVESCVQYTSCELCLGSRD 506

Query: 525  PHCGWCVLHNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETYNV 584
            PHCGWCVLH+ C+R++ CER+ EP+RFA+++ QCV+LTV P N+SV+   V LVL+ +NV
Sbjct: 507  PHCGWCVLHSICSRRDACERADEPQRFAADLLQCVQLTVQPRNVSVTMSQVPLVLQAWNV 566

Query: 585  PELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGM 644
            P+LSAGVNC+FED +E + ++   +I C SP+A+EV  I    GD  VV+L LKSKETG 
Sbjct: 567  PDLSAGVNCSFEDFTESESVLEDGRIHCRSPSAREVAPITRGQGDQRVVKLYLKSKETGK 626

Query: 645  TFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCPQL 704
             FAS  FVFYNCSVH SCLSCV   + CHWCKYRHVCTH+   C+F EGRV + EDCPQ+
Sbjct: 627  KFASVDFVFYNCSVHQSCLSCVNGSFPCHWCKYRHVCTHNVADCAFLEGRVNVSEDCPQI 686

Query: 705  LRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQCQN 764
            L   +I VPV V+KPITL A+NLPQPQSGQRGYEC+ +I GS  RV ALRFNSSS+QCQN
Sbjct: 687  LPSTQIYVPVGVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTALRFNSSSLQCQN 746

Query: 765  TSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFACG 824
            +SYSYEG ++++LPV L+VVWNG+F IDNP   + HLYKC A+RESCGLCLKADP F CG
Sbjct: 747  SSYSYEGNDVSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECG 806

Query: 825  WCQGPGQCTLRQHCPAQ-ESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGENL 883
            WC    +C+LR HC A   + W+      S+CT+P+I ++ P TGPR+GGT++TI GENL
Sbjct: 807  WCVAERRCSLRHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENL 866

Query: 884  GLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQ-HAGFVEICVAVCRPEFM 942
            GL F D+   V+V  V CSP+   YI AEQIVCE+G+A   + H   VE+CV  C P + 
Sbjct: 867  GLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYR 926

Query: 943  ARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPS 1002
            A S + + F+T T   + PSRGP+SGGT + I G++LNAGS+V V  G +PC F  R+  
Sbjct: 927  ALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAGSDVAVSVGGRPCSFSWRNSR 986

Query: 1003 YIVCNTTSSDEVLEMKVSVQVDRAKI-HQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVW 1061
             I C T          + + ++RA++ + ++ + Y EDPTI+RI+PEWSI SG T + V 
Sbjct: 987  EIRCLTPPGQSPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLLTVT 1046

Query: 1062 GTHLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFI 1121
            GT+L  ++ P+IRAK+GG E  N C V N T M C+AP++A       +L ERP+E GF+
Sbjct: 1047 GTNLATVREPRIRAKYGGIERENGCLVYNDTTMVCRAPSVANPVRSPPELGERPDELGFV 1106

Query: 1122 LDNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNY 1181
            +DNV+SLL+LN T+F YYP+PV E   P+G+LELKP +P+ILKG+NL+PP A GN +LNY
Sbjct: 1107 MDNVRSLLVLNSTSFLYYPDPVLEPLSPTGLLELKPSSPLILKGRNLLPP-APGNSRLNY 1165

Query: 1182 TVLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVS 1241
            TVL+G  PCT+TVS+ QLLCE+PNL G+HKV  R GG E+SPG + +  DS L+LPAIV 
Sbjct: 1166 TVLIGSTPCTLTVSETQLLCEAPNLTGQHKVTVRAGGFEFSPGTLQVYSDSLLTLPAIVG 1225

Query: 1242 IAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIH 1301
            I   GGLL++ IVAVLIAYKRKSR++D TLKRLQ+QMDNLESRVALECKEAFAELQTDIH
Sbjct: 1226 IGGGGGLLLLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECKEAFAELQTDIH 1285

Query: 1302 ELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINN 1361
            ELT+DLDGAGIPFLDYRTY MRVLFPGIEDHPVL+++EV    Q  VEK L LF QL+  
Sbjct: 1286 ELTNDLDGAGIPFLDYRTYAMRVLFPGIEDHPVLKEMEV----QANVEKSLTLFGQLLTK 1341

Query: 1362 KVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKN 1421
            K FLL+FIRTLE+QRSFSMRDRGNVASLIMT LQ ++EYAT VLKQLL+DLI+KNLESKN
Sbjct: 1342 KHFLLTFIRTLEAQRSFSMRDRGNVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKN 1401

Query: 1422 HPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEA 1481
            HPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLF L+CAIKQQMEKGPIDAITGEA
Sbjct: 1402 HPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEA 1461

Query: 1482 RYSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVP 1541
            RYSLSEDKLIRQQIDYKTL L+CV+P+N N+PEVPVK L+CDT+TQ KEK+LDA +K VP
Sbjct: 1462 RYSLSEDKLIRQQIDYKTLTLNCVNPENENAPEVPVKGLDCDTVTQAKEKLLDAAYKGVP 1521

Query: 1542 CSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQ 1601
             S RPKAADMDLEWRQG  AR+ILQDED+TTKI+NDWKRLNTLAHYQV DGS VALV KQ
Sbjct: 1522 YSQRPKAADMDLEWRQGRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQ 1581

Query: 1602 VTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHG 1661
             +AYN  N+ST ++ S S+YE+M+R   SPDSLRSRTPMITPDLESG K+WHLVKNH+H 
Sbjct: 1582 TSAYNISNSSTFTK-SLSRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDHL 1640

Query: 1662 DQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLD 1721
            DQ+EGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLD
Sbjct: 1641 DQREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLD 1700

Query: 1722 EQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDS 1781
            EQADKH IHD  VRHTWKSNCLPLRFWVN+IKNPQFVFDIHKNSITDACLSVVAQTFMDS
Sbjct: 1701 EQADKHQIHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDS 1760

Query: 1782 CSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHM 1841
            CSTSEH+LGKDSPSNKLLYAKDIP+YK+WVERYY+DI KMPAISDQDM+AYLAEQSR+H+
Sbjct: 1761 CSTSEHKLGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLHL 1820

Query: 1842 NEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1894
            ++FN+MSAL EI+SY+ KY +EIL  L+ D+Q  +Q+L  KLEQV+  M+L S
Sbjct: 1821 SQFNSMSALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQVVDTMALSS 1873


>gi|59710104 plexin A3 [Homo sapiens]
          Length = 1871

 Score = 2306 bits (5975), Expect = 0.0
 Identities = 1122/1846 (60%), Positives = 1412/1846 (76%), Gaps = 13/1846 (0%)

Query: 53   HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
            HL V   TG +++GAVNR++KL+ +L  L  H TGP EDN +CYPP  ++ C   L   +
Sbjct: 35   HLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVD 94

Query: 113  NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGV 172
            N+NK+LLIDY   RL+ACGS++QGIC+ LRL+DLFKLGEP+H+KEHYLSG  E  S+ GV
Sbjct: 95   NINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGV 154

Query: 173  IVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSD 232
            IV       KLF+ TAVDGK EYFPT+SSRKL  + ++  MF+ V+ DEFV+S IKIPSD
Sbjct: 155  IVEQGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSD 214

Query: 233  TFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNS 292
            T ++ P FDIYY+YGF S +FVYFLTLQ +       T  E+ +TSK+VR+C  D+ F S
Sbjct: 215  TLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYS 274

Query: 293  YVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDE 352
            YVE PIGC   GVEYRL+Q+A+L+K G +L + LGV  D+D+LFT+FS+GQK +     +
Sbjct: 275  YVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQ 334

Query: 353  SALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAP 412
            + LC+F L  IN  I+ R+QSCYRGEGTL L WL  K++PC +  + I+ NFCGL +N P
Sbjct: 335  TILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTPMQINGNFCGLVLNQP 394

Query: 413  LGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYET 472
            LG   ++ G+P+  +  D M SV AY Y+ HS+ F+GT+SG LKK+RVDG + +A  YET
Sbjct: 395  LGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQ-DAHLYET 453

Query: 473  VQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVL 532
            V VVD  P+LRD+ FS DH  +Y++SE+Q++++PVE+C QYQSC  CLGSGDPHCGWCVL
Sbjct: 454  VPVVDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVL 513

Query: 533  HNTCTRKERCERSKEPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETYNVPELSAGVN 592
             + C R+  C  +  P  FA E+ +CV++ V PNN+SV+   V L +  +NVP+LSAGV+
Sbjct: 514  RHRCCREGACLGASAPHGFAEELSKCVQVRVRPNNVSVTSPGVQLTVTLHNVPDLSAGVS 573

Query: 593  CTFEDLSEMDG-LVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMTFASTSF 651
            C FE  +E +  L+   ++ C SP+ +E+  +   +G    V+LQL SKETG+ FA   F
Sbjct: 574  CAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGADF 633

Query: 652  VFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCPQLLRVDKIL 711
            VFYNCSV  SC+SCV SPY CHWCKYRH CT  P  CSFQEGRV  PE CP++L    +L
Sbjct: 634  VFYNCSVLQSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPEILPSGDLL 693

Query: 712  VPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQCQNTSYSYEG 771
            +PV V++P+TL+AKNLPQPQSGQ+ YEC++ +QG +QRVPA+RFNSSSVQCQN SYSYEG
Sbjct: 694  IPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEG 753

Query: 772  MEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFACGWCQGPGQ 831
             E  +  ++ +VVW+G F ID P   +  LYKC A R SCGLCLKADP F CGWC    +
Sbjct: 754  DEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRFNCGWCISEHR 813

Query: 832  CTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFRDIA 891
            C LR HCPA ++ W+ LS   ++C++PRIT+I P+ GP+EGGT+VTI G+NLGL  R++ 
Sbjct: 814  CQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVGDNLGLLSREVG 873

Query: 892  SHVKVAGVECSPLVDGYIPAEQIVCEMGEA-KPSQHAGFVEICVAVCRPEFMARSSQLYY 950
              ++VAGV C+ +   YI AE+IVCEM E+  PS   G VE+CV  C  +F  +S Q+Y 
Sbjct: 874  --LRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSADFRTQSEQVYS 931

Query: 951  FMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPSYIVC-NTT 1009
            F+T T   + PSRGP SGGT++TI+G++L+AGS V V      C F RR    IVC +  
Sbjct: 932  FVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQFVRRDAKAIVCISPL 991

Query: 1010 SSDEVLEMKVSVQVDRAKIHQ-DLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLI 1068
            S+    +  +++ +DRA I    L++ Y +DPT+ R+EP WSI++G+T I V GTHL  +
Sbjct: 992  STLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVSGTHLLTV 1051

Query: 1069 QNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQSL 1128
            Q P++RAK+ G E  N C+V+N T M C+AP + LG        E P+EFGF+LD+VQ+ 
Sbjct: 1052 QEPRVRAKYRGIETTNTCQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQTA 1111

Query: 1129 LILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEK 1188
              LN+++FTYYP+P FE  GPSG+L++KPG+ ++LKGKNLIP  AG + +LNYTVL+G +
Sbjct: 1112 RSLNRSSFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGSS-RLNYTVLIGGQ 1170

Query: 1189 PCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSIAVAGGL 1248
            PC++TVSD QLLC+SP+  GR  VM  VGG+E+  G ++I+ +  L+LPA++ +A  GGL
Sbjct: 1171 PCSLTVSDTQLLCDSPSQTGRQPVMVLVGGLEFWLGTLHISAERALTLPAMMGLAAGGGL 1230

Query: 1249 LIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHELTSDLD 1308
            L++ I AVL+AYKRK++++D TLKRLQ+QMDNLESRVALECKEAFAELQTDI+ELT+ +D
Sbjct: 1231 LLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINELTNHMD 1290

Query: 1309 GAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNKVFLLSF 1368
               IPFLDYRTY +RVLFPGIE HPVL++L+ P      VEK L+LF QL++++ F+L+F
Sbjct: 1291 EVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTP----PNVEKALRLFGQLLHSRAFVLTF 1346

Query: 1369 IRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNHPKLLLR 1428
            I TLE+Q SFSMRDRG VASL M  LQS+L+YAT +LKQLLADLI+KNLESKNHPKLLLR
Sbjct: 1347 IHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESKNHPKLLLR 1406

Query: 1429 RTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEARYSLSED 1488
            RTESVAEKMLTNWFTFLL+KFLKECAGEPLF L+CAIKQQMEKGPIDAITGEARYSLSED
Sbjct: 1407 RTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGEARYSLSED 1466

Query: 1489 KLIRQQIDYKTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPCSHRPKA 1548
            KLIRQQIDYKTL L CV P+N  S +VPVK+LNCD+ITQ K+K+LD ++K +P S RPKA
Sbjct: 1467 KLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNCDSITQAKDKLLDTVYKGIPYSQRPKA 1526

Query: 1549 ADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVALVSKQVTAYNAV 1608
             DMDLEWRQG   R+ILQDED+TTKIE DWKRLN+LAHYQV DGS+VALV KQV+AYN  
Sbjct: 1527 EDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSLVALVPKQVSAYNMA 1586

Query: 1609 NNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGDQKEGDR 1668
            N+ T +R S S+YE+++R   SPDSLRSR PMITPD E+G K+WHLVKNH+H D +EGDR
Sbjct: 1587 NSFTFTR-SLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHLVKNHDHADHREGDR 1645

Query: 1669 GSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHG 1728
            GSKMVSEIYLTRLLATKGTLQKFVDDLFET+FSTAHRGSALPLAIKYMFDFLDEQAD+  
Sbjct: 1646 GSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSALPLAIKYMFDFLDEQADQRQ 1705

Query: 1729 IHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHR 1788
            I DP VRHTWKSNCLPLRFWVN+IKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHR
Sbjct: 1706 ISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHR 1765

Query: 1789 LGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMNEFNTMS 1848
            LGKDSPSNKLLYAKDIP+YK+WVERYY DI KM +ISDQDM+AYL EQSR+H ++F+ +S
Sbjct: 1766 LGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDMDAYLVEQSRLHASDFSVLS 1825

Query: 1849 ALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS 1894
            AL+E++ YV KY +EIL  LD D  C K KL  KLEQ+I+L+S DS
Sbjct: 1826 ALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISLVSSDS 1871


>gi|149363636 plexin B2 [Homo sapiens]
          Length = 1838

 Score =  936 bits (2418), Expect = 0.0
 Identities = 640/1938 (33%), Positives = 988/1938 (50%), Gaps = 194/1938 (10%)

Query: 24   TLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVT 83
            TLL    A  S + R    FR E  +  NHL VDE +G +YLGAVN +Y+L + L++   
Sbjct: 9    TLLGLLGAGASLRPRKLDFFRSE--KELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQ 66

Query: 84   HETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRL 143
              TGP  DN KC PP     C+E    T+NVN++LL+D    RL+ CGSL++GIC L  L
Sbjct: 67   VATGPALDNKKCTPPIEASQCHEA-EMTDNVNQLLLLDPPRKRLVECGSLFKGICALRAL 125

Query: 144  ED--LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISS 201
             +  L    E    ++ +++  +E  +  G++ S     D++      +G  +    +S+
Sbjct: 126  SNISLRLFYEDGSGEKSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVST 185

Query: 202  RKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQP 261
            R L +    +   AY  H  + A  +   +  F          V  F  G +V+F+  Q 
Sbjct: 186  RLLDRTDSREAFEAYTDHATYKAGYLSTNTQQF----------VAAFEDGPYVFFVFNQQ 235

Query: 262  EMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAV 321
            +       T         L R+C+ED  + SY+E+ + C    +      AA+    G  
Sbjct: 236  DKHPARNRTL--------LARMCREDPNYYSYLEMDLQCRDPDIH----AAAF----GTC 279

Query: 322  LGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTL 381
            L  ++       +L+ VFS+  +        + LC+F L +++ +++    +CY G    
Sbjct: 280  LAASVAAPGSGRVLYAVFSRDSRSS--GGPGAGLCLFPLDKVHAKMEANRNACYTGTREA 337

Query: 382  DLAWLKV--KDIPCSSALLTIDDNF-CGLD-MNAPLGVSDMVRGIPVFTEDRDRMTSVIA 437
               + K    DI C         +F CG + +  PLG  D +RG  V       +T+V  
Sbjct: 338  RDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTV 397

Query: 438  YVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIM 497
                NH++AF+GT  G++ K+ +  P G + +Y+++ V     V RD+  S D   LY M
Sbjct: 398  AAENNHTVAFLGTSDGRILKVYLT-PDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAM 456

Query: 498  SERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRRFA-SEMK 556
            ++ ++ R+PV+ C  Y +C +C  S DP+CGWCV+   CTRK  C R++E   +  S  K
Sbjct: 457  TQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRSK 516

Query: 557  QCVRLT-VHPNNISV-SQYNVLLVLETYNVPELSAGVNCTFEDLSEMDGLVVGNQIQCYS 614
             CV +T   P N+S  +Q  V L +           + C F +       V G  + C S
Sbjct: 517  SCVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEEDELLCLFGESPPHPARVEGEAVICNS 576

Query: 615  PAAKEVPRIITENGDHHV-VQLQLKSKETGMTFASTSFVFYNCSVHNS------CLSCVE 667
            P++  +P  +T  G  HV V +QL  +   +   S  + FY+C    S      C+SCV 
Sbjct: 577  PSS--IP--VTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISCVS 632

Query: 668  SPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCPQLLRVDKILVPVEVIKPITLKAKNL 727
            + + C W    H C            R  + + CPQ L    +++P+     +  + KNL
Sbjct: 633  NRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETDVNFQGKNL 692

Query: 728  PQPQSGQRGYECILNIQGSEQRVPA--LRFNSSSVQCQNTSYSYEGMEINN-----LPVE 780
                           ++GS   V +  L+F       ++ ++++   ++++     LP+ 
Sbjct: 693  D-------------TVKGSSLHVGSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLH 739

Query: 781  LTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFACGWCQGPGQCTLRQHCPA 840
            L V   G  NID+     V LY C   R  C LC  A+PD+ C WC G  +C     C  
Sbjct: 740  LYVKSYGK-NIDSKLH--VTLYNCSFGRSDCSLCRAANPDYRCAWCGGQSRCVYEALC-- 794

Query: 841  QESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVE 900
                        S+C  P IT I P TGP  GG ++TI G NLG++  DI   + VAG  
Sbjct: 795  ---------NTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDI-QRISVAGRN 844

Query: 901  CSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARS--SQLYYFMTLTLSD 958
            CS   + Y  + +IVC + EA  +   G VE+ V       + RS  +  + F       
Sbjct: 845  CSFQPERYSVSTRIVCVI-EAAETPFTGGVEVDVF----GKLGRSPPNVQFTFQQPKPLS 899

Query: 959  LKPSRGPMSGGTQVTITGTNLNAGS--NVVVMFGKQPCLFHRRSPSYIVCNTTSSDEVLE 1016
            ++P +GP +GGT +TI GT+L+ GS  +V V     PC   +   + + C T       +
Sbjct: 900  VEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFG-AQLQCVTGPQATRGQ 958

Query: 1017 MKVSVQVDRAKI-HQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIRA 1075
            M + V    + + +  + F Y E+P +   EP  S  SG   I V G    LIQ   +  
Sbjct: 959  MLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAM-- 1016

Query: 1076 KHGGKEHINICEVLNATEMTCQA----PALALGPDH-----------QSDLTERPEEFGF 1120
                   + I E L + +   +A    P   +G D+              + E PE +  
Sbjct: 1017 -------VVIAEPLQSWQPPREAESLQPMTVVGTDYVFHNDTKVVFLSPAVPEEPEAYNL 1069

Query: 1121 I----LDNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGN 1176
                 +D  ++LL      F Y P+P FE F  +G ++ +    I  +G NL   +    
Sbjct: 1070 TVLIEMDGHRALLRTEAGAFEYVPDPTFENF--TGGVKKQVNKLIHARGTNLNKAMTLQE 1127

Query: 1177 VKLNYTVLVGEKPCTV-TVSDVQLLCESPNLIGRHK-------------VMARVGGMEYS 1222
             +      VG + CT+ T+++  L CE P +    K              + + G  E+ 
Sbjct: 1128 AE----AFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWV 1183

Query: 1223 PGMVYI---APDSPLSLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMD 1279
             G V       D PLSL  I+ + +    +++ I   +  Y RKS++++   ++++ Q++
Sbjct: 1184 LGRVEYDTRVSDVPLSL--ILPLVIVP--MVVVIAVSVYCYWRKSQQAEREYEKIKSQLE 1239

Query: 1280 NLESRVALECKEAFAELQTDIHELTSDLDGAGIPFLDYRTYTMRVLF----PGIEDHPVL 1335
             LE  V   CK+ F +L  ++ + T+D+  AGIP LDY+TYT RV F     G +D  + 
Sbjct: 1240 GLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMIT 1299

Query: 1336 RDLEVPGYRQERVEKGLKLFAQLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQ 1395
              L++P  R+  VE+ L  F+ L+N+K FL++FI TLE+QR FS R +   ASL+   L 
Sbjct: 1300 GKLDIPEPRRPVVEQALYQFSNLLNSKSFLINFIHTLENQREFSARAKVYFASLLTVALH 1359

Query: 1396 SKLEYATDVLKQLLADLIDKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAG 1455
             KLEY TD++  L  +L+++ + +KN PKL+LRR+E+V E+ML+NW +  LY++LK+ AG
Sbjct: 1360 GKLEYYTDIMHTLFLELLEQYVVAKN-PKLMLRRSETVVERMLSNWMSICLYQYLKDSAG 1418

Query: 1456 EPLFSLFCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLVLSCVSPDNANSPEV 1515
            EPL+ LF AIK Q+EKGP+DA+  +A+Y+L++  L+   ++Y  L +S +  D      +
Sbjct: 1419 EPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIVQDE-GVDAI 1477

Query: 1516 PVKILNCDTITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIE 1575
            PVK+LNCDTI+QVKEKI+D +++  PCS  P+   + LEWR GS A+ IL D D+T++ E
Sbjct: 1478 PVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQ-ILSDLDLTSQRE 1536

Query: 1576 NDWKRLNTLAHYQVPDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLR 1635
              WKR+NTL HY V DG+ + L           +   VS+      +++    G   +L 
Sbjct: 1537 GRWKRVNTLMHYNVRDGATLIL-----------SKVGVSQQPEDSQQDL---PGERHAL- 1581

Query: 1636 SRTPMITPDLESGVKMWHLVKNHEHGDQKEGDRGS-------KMVSEIYLTRLLATKGTL 1688
                     LE   ++WHLV+  +  D+ +  RGS       K ++EIYLTRLL+ KGTL
Sbjct: 1582 ---------LEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTRLLSVKGTL 1632

Query: 1689 QKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFW 1748
            Q+FVD+ F+++ +  H   A+P A+KY FDFLDEQA+KH I D    H WK+N LPLRFW
Sbjct: 1633 QQFVDNFFQSVLAPGH---AVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWKTNSLPLRFW 1689

Query: 1749 VNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYK 1808
            VN++KNP F+FD+H + + DA LSV+AQTFMD+C+ +EH+L +DSPSNKLLYAK+I +YK
Sbjct: 1690 VNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYK 1749

Query: 1809 NWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPL 1868
              VE YY  I +M  +SDQDMN +LAE SR H +  NT+ AL +++ Y  KY +EI+  L
Sbjct: 1750 KMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINAL 1809

Query: 1869 DHDDQCGKQKLAYKLEQV 1886
            + D    K +LA++L+Q+
Sbjct: 1810 EEDPAAQKMQLAFRLQQI 1827


>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
          Length = 522

 Score =  932 bits (2409), Expect = 0.0
 Identities = 461/469 (98%), Positives = 462/469 (98%)

Query: 1   MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
           MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT
Sbjct: 1   MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60

Query: 61  GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
           GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI
Sbjct: 61  GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120

Query: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
           DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD
Sbjct: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180

Query: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
           DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF
Sbjct: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240

Query: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
           DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC
Sbjct: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300

Query: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
           ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL
Sbjct: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360

Query: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
           KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR
Sbjct: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420

Query: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQ 469
           GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKK    GP+G   Q
Sbjct: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQ 469


>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
          Length = 492

 Score =  927 bits (2396), Expect = 0.0
 Identities = 457/458 (99%), Positives = 458/458 (100%)

Query: 1   MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60
           MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT
Sbjct: 1   MKAMPWNWTCLLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERT 60

Query: 61  GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120
           GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI
Sbjct: 61  GHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLI 120

Query: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180
           DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD
Sbjct: 121 DYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLD 180

Query: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240
           DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF
Sbjct: 181 DKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDF 240

Query: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300
           DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC
Sbjct: 241 DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGC 300

Query: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360
           ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL
Sbjct: 301 ERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFIL 360

Query: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420
           KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR
Sbjct: 361 KQINDRIKERLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVR 420

Query: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKI 458
           GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKK+
Sbjct: 421 GIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKM 458


>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
          Length = 1932

 Score =  927 bits (2395), Expect = 0.0
 Identities = 655/1991 (32%), Positives = 992/1991 (49%), Gaps = 246/1991 (12%)

Query: 25   LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
            LL+  P PL+   R        P    NHL +    G +Y+GAVNR+++LS +L++    
Sbjct: 56   LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 110

Query: 85   ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
             TGP  D+P C P R    C +    T+N N++LL+  +   L+ACG + QG+C+  RL 
Sbjct: 111  VTGPVIDSPDCVPFRDPAECPQA-QLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 169

Query: 145  DLFK-LGEPYHKKEHYLSGVNESG-SVFGVIVSYSNLDDKLFIATAVDGKPEY-FPTISS 201
            D+ + L +     +      N  G +  G++V     D  L +A  + GK     P ++ 
Sbjct: 170  DVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRD-LLLVARGLAGKLSAGVPPLAI 228

Query: 202  RKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTL 259
            R+L  +    ++G+   V  D                  D++  YV  F+     YF+  
Sbjct: 229  RQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYFVFR 272

Query: 260  QPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAG 319
            +            +  Y S + R+C  DT   SYVEVP+ C+  G    L+QAA+L+  G
Sbjct: 273  RR-------GARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLAP-G 320

Query: 320  AVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY---- 375
             +LG              VF+ G +       ++ALC F + ++   +++  + CY    
Sbjct: 321  TLLG--------------VFAAGPRGT-----QAALCAFPMVELGASMEQARRLCYTAGG 361

Query: 376  RGEGTLDLAWLKVKDIP-CSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIPVF 425
            RG    + A ++      C +  L   +++ CG       +    PL V  +++ G PV 
Sbjct: 362  RGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPV- 420

Query: 426  TEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLR-D 484
                   ++V A     H +AF+G   G+L K+ + G +G    Y + QV  PG  +  D
Sbjct: 421  -------SAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQV--YHSQQVGPPGSAISPD 471

Query: 485  MAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKERCER 544
            +        LY+++  Q+ R+PV +C Q+  C  CL + DP CGWCVL   CTRK +C R
Sbjct: 472  LLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGR 531

Query: 545  SKEPRRFA---SEMKQCVRLTV-----HPNNISVSQYNVLLVLETYNVPELSAGVNCTFE 596
            + +  ++     E   C+ +       HP      Q  V L +    + +     +C F 
Sbjct: 532  AGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQ---EQGQVTLSVPRLPILDADEYFHCAFG 588

Query: 597  DLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMTFASTSFVFYNC 656
            D   +   V G  + C +P   +VP +     DH  V L L  ++  +T A+T+F FY+C
Sbjct: 589  DYDSL-AHVEGPHVACVTPPQDQVP-LNPPGTDHVTVPLALMFED--VTVAATNFSFYDC 644

Query: 657  SVHNS------CLSCVESPYRCHWCK------YRHVCTHDPKTC-SFQEGRVKL--PEDC 701
            S   +      C +CV S +RCHWC       Y   C    +T  S QE  +++  P  C
Sbjct: 645  SAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGAC 704

Query: 702  PQLLRV-DKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPAL----RFN 756
            PQ+  +    LVPV     + L+ +NL   +     + C L + G  + +PA       +
Sbjct: 705  PQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGD 764

Query: 757  SSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLK 816
            S  + CQ   + Y  M    LPV + V       +DN     V LY C      C  C  
Sbjct: 765  SGLIHCQAHQF-YPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQA 823

Query: 817  ADPDFACGWC-QGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTK 875
            A+    C WC  G   C     CP    + L        C  P I  + P+TGP EGG  
Sbjct: 824  ANRSLGCLWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEPLTGPPEGGLA 875

Query: 876  VTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVA 935
            +TI G NLG  F D+   V VA   C+P    Y  + +IVC    A P+   G V + + 
Sbjct: 876  LTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPA-PNGTTGPVRVAIK 934

Query: 936  VCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPC- 994
               P     SSQ + +    L  L P  GP +GGTQ+TI G +L  G N     G QPC 
Sbjct: 935  SQPPGI---SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCP 991

Query: 995  LFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAKIHQDLV---FQYVEDPTIVRIEPEWSI 1051
            +     P  IVC T       E  V V    A+  + L+   F+Y  +P +V  EP  S 
Sbjct: 992  ILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQ--RTLLASPFRYTANPQLVAAEPSASF 1049

Query: 1052 VSGNTPIAVWGTHLDLIQNP----------QIRAKH------------------------ 1077
              G   I V GT LD++Q P          +++A                          
Sbjct: 1050 RGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQ 1109

Query: 1078 ---GGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQS--LLILN 1132
               G  +   +C V +++ + C++PA+   PD        P+   F LDNVQ        
Sbjct: 1110 LGGGLLQCSTVCSVNSSSLLLCRSPAV---PDRA-----HPQRVFFTLDNVQVDFASASG 1161

Query: 1133 KTNFTYYPNPVFEAF---GPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKP 1189
               F Y PNP        GP+    LKPG  + ++G+ L   ++   V+++    +G   
Sbjct: 1162 GQGFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVH----IGRGE 1217

Query: 1190 CTV-TVSDVQLLCESP-------NLIGRHKVMARVGGMEYSPGMVYIAPDSPLS---LPA 1238
            C V T++   L CE P       N  G  + + ++G ++ + G V    + PLS   + A
Sbjct: 1218 CLVKTLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1277

Query: 1239 IVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQT 1298
               + +   +LI  ++ + + Y+ KS+++    +++ +Q+++LE+ V  +C++ F +L T
Sbjct: 1278 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1337

Query: 1299 DIHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQE--RVEKGLKLFA 1356
            ++ +L+SDL+G+GIPFLDYRTY  R  FPG    P+    E PG       V +GL   +
Sbjct: 1338 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1397

Query: 1357 QLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKN 1416
             L+N+K+FLL+ I TLE Q SFS RDR +VASL+   L  KLEY TD+++ LL DL    
Sbjct: 1398 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1457

Query: 1417 LESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDA 1476
            +    +PKL+LRRTE++ EK+LTNW +  LY FL+E AGEPL+ LF AI+ Q++KGP+DA
Sbjct: 1458 VH--RNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDA 1515

Query: 1477 ITGEARYSLSEDKLIRQQIDYKTLVLSCV-------SPDNANSPEVPVKILNCDTITQVK 1529
            +TG+A+ +L++ +L+R+ ++++ L L  +       +  ++    VP ++L+ DTITQVK
Sbjct: 1516 VTGKAKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1575

Query: 1530 EKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQV 1589
            EK+LD ++K  P S RP    +DLEWR G    + L DED+T+  +N WKRLNTL HY+V
Sbjct: 1576 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1635

Query: 1590 PDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGV 1649
            PDG+ V LV +          ST+S++ A +             L    P +    E GV
Sbjct: 1636 PDGATVGLVPQ------LHRGSTISQSLAQRCP-----------LGENIPTLEDGEEGGV 1678

Query: 1650 KMWHLVKNHEHGD----------QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETI 1699
             +WHLVK  E  +          ++E  R +K + EIYLTRLL+ KGTLQKFVDD F+ I
Sbjct: 1679 CLWHLVKATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQKFVDDTFQAI 1737

Query: 1700 FSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVF 1759
             S       +P+A+KY+FD LDE A+KHGI DP   H WK+N L LRFWVN +KNPQ +F
Sbjct: 1738 LSV---NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIF 1794

Query: 1760 DIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIG 1819
            D+  +   DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK  VERYY+DI 
Sbjct: 1795 DVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIR 1854

Query: 1820 KMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKL 1879
            +    S Q+MN+ LAE S  + +  + + AL E+++++ +Y ++I+  L+ D    K +L
Sbjct: 1855 QSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQL 1914

Query: 1880 AYKLEQVITLM 1890
            A +L+QV  L+
Sbjct: 1915 ACRLQQVAALV 1925


>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
          Length = 1909

 Score =  927 bits (2395), Expect = 0.0
 Identities = 655/1991 (32%), Positives = 992/1991 (49%), Gaps = 246/1991 (12%)

Query: 25   LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
            LL+  P PL+   R        P    NHL +    G +Y+GAVNR+++LS +L++    
Sbjct: 33   LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 87

Query: 85   ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
             TGP  D+P C P R    C +    T+N N++LL+  +   L+ACG + QG+C+  RL 
Sbjct: 88   VTGPVIDSPDCVPFRDPAECPQA-QLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 146

Query: 145  DLFK-LGEPYHKKEHYLSGVNESG-SVFGVIVSYSNLDDKLFIATAVDGKPEY-FPTISS 201
            D+ + L +     +      N  G +  G++V     D  L +A  + GK     P ++ 
Sbjct: 147  DVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRD-LLLVARGLAGKLSAGVPPLAI 205

Query: 202  RKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTL 259
            R+L  +    ++G+   V  D                  D++  YV  F+     YF+  
Sbjct: 206  RQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYFVFR 249

Query: 260  QPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAG 319
            +            +  Y S + R+C  DT   SYVEVP+ C+  G    L+QAA+L+  G
Sbjct: 250  RR-------GARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLAP-G 297

Query: 320  AVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY---- 375
             +LG              VF+ G +       ++ALC F + ++   +++  + CY    
Sbjct: 298  TLLG--------------VFAAGPRGT-----QAALCAFPMVELGASMEQARRLCYTAGG 338

Query: 376  RGEGTLDLAWLKVKDIP-CSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIPVF 425
            RG    + A ++      C +  L   +++ CG       +    PL V  +++ G PV 
Sbjct: 339  RGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPV- 397

Query: 426  TEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLR-D 484
                   ++V A     H +AF+G   G+L K+ + G +G    Y + QV  PG  +  D
Sbjct: 398  -------SAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQV--YHSQQVGPPGSAISPD 448

Query: 485  MAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKERCER 544
            +        LY+++  Q+ R+PV +C Q+  C  CL + DP CGWCVL   CTRK +C R
Sbjct: 449  LLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGR 508

Query: 545  SKEPRRFA---SEMKQCVRLTV-----HPNNISVSQYNVLLVLETYNVPELSAGVNCTFE 596
            + +  ++     E   C+ +       HP      Q  V L +    + +     +C F 
Sbjct: 509  AGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQ---EQGQVTLSVPRLPILDADEYFHCAFG 565

Query: 597  DLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMTFASTSFVFYNC 656
            D   +   V G  + C +P   +VP +     DH  V L L  ++  +T A+T+F FY+C
Sbjct: 566  DYDSL-AHVEGPHVACVTPPQDQVP-LNPPGTDHVTVPLALMFED--VTVAATNFSFYDC 621

Query: 657  SVHNS------CLSCVESPYRCHWCK------YRHVCTHDPKTC-SFQEGRVKL--PEDC 701
            S   +      C +CV S +RCHWC       Y   C    +T  S QE  +++  P  C
Sbjct: 622  SAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGAC 681

Query: 702  PQLLRV-DKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPAL----RFN 756
            PQ+  +    LVPV     + L+ +NL   +     + C L + G  + +PA       +
Sbjct: 682  PQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGD 741

Query: 757  SSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLK 816
            S  + CQ   + Y  M    LPV + V       +DN     V LY C      C  C  
Sbjct: 742  SGLIHCQAHQF-YPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQA 800

Query: 817  ADPDFACGWC-QGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTK 875
            A+    C WC  G   C     CP    + L        C  P I  + P+TGP EGG  
Sbjct: 801  ANRSLGCLWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEPLTGPPEGGLA 852

Query: 876  VTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVA 935
            +TI G NLG  F D+   V VA   C+P    Y  + +IVC    A P+   G V + + 
Sbjct: 853  LTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPA-PNGTTGPVRVAIK 911

Query: 936  VCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPC- 994
               P     SSQ + +    L  L P  GP +GGTQ+TI G +L  G N     G QPC 
Sbjct: 912  SQPPGI---SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCP 968

Query: 995  LFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAKIHQDLV---FQYVEDPTIVRIEPEWSI 1051
            +     P  IVC T       E  V V    A+  + L+   F+Y  +P +V  EP  S 
Sbjct: 969  ILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQ--RTLLASPFRYTANPQLVAAEPSASF 1026

Query: 1052 VSGNTPIAVWGTHLDLIQNP----------QIRAKH------------------------ 1077
              G   I V GT LD++Q P          +++A                          
Sbjct: 1027 RGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQ 1086

Query: 1078 ---GGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQS--LLILN 1132
               G  +   +C V +++ + C++PA+   PD        P+   F LDNVQ        
Sbjct: 1087 LGGGLLQCSTVCSVNSSSLLLCRSPAV---PDRA-----HPQRVFFTLDNVQVDFASASG 1138

Query: 1133 KTNFTYYPNPVFEAF---GPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKP 1189
               F Y PNP        GP+    LKPG  + ++G+ L   ++   V+++    +G   
Sbjct: 1139 GQGFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVH----IGRGE 1194

Query: 1190 CTV-TVSDVQLLCESP-------NLIGRHKVMARVGGMEYSPGMVYIAPDSPLS---LPA 1238
            C V T++   L CE P       N  G  + + ++G ++ + G V    + PLS   + A
Sbjct: 1195 CLVKTLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1254

Query: 1239 IVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQT 1298
               + +   +LI  ++ + + Y+ KS+++    +++ +Q+++LE+ V  +C++ F +L T
Sbjct: 1255 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1314

Query: 1299 DIHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQE--RVEKGLKLFA 1356
            ++ +L+SDL+G+GIPFLDYRTY  R  FPG    P+    E PG       V +GL   +
Sbjct: 1315 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1374

Query: 1357 QLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKN 1416
             L+N+K+FLL+ I TLE Q SFS RDR +VASL+   L  KLEY TD+++ LL DL    
Sbjct: 1375 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1434

Query: 1417 LESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDA 1476
            +    +PKL+LRRTE++ EK+LTNW +  LY FL+E AGEPL+ LF AI+ Q++KGP+DA
Sbjct: 1435 VH--RNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDA 1492

Query: 1477 ITGEARYSLSEDKLIRQQIDYKTLVLSCV-------SPDNANSPEVPVKILNCDTITQVK 1529
            +TG+A+ +L++ +L+R+ ++++ L L  +       +  ++    VP ++L+ DTITQVK
Sbjct: 1493 VTGKAKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1552

Query: 1530 EKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQV 1589
            EK+LD ++K  P S RP    +DLEWR G    + L DED+T+  +N WKRLNTL HY+V
Sbjct: 1553 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1612

Query: 1590 PDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGV 1649
            PDG+ V LV +          ST+S++ A +             L    P +    E GV
Sbjct: 1613 PDGATVGLVPQ------LHRGSTISQSLAQRCP-----------LGENIPTLEDGEEGGV 1655

Query: 1650 KMWHLVKNHEHGD----------QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETI 1699
             +WHLVK  E  +          ++E  R +K + EIYLTRLL+ KGTLQKFVDD F+ I
Sbjct: 1656 CLWHLVKATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQKFVDDTFQAI 1714

Query: 1700 FSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVF 1759
             S       +P+A+KY+FD LDE A+KHGI DP   H WK+N L LRFWVN +KNPQ +F
Sbjct: 1715 LSV---NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIF 1771

Query: 1760 DIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIG 1819
            D+  +   DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK  VERYY+DI 
Sbjct: 1772 DVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIR 1831

Query: 1820 KMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKL 1879
            +    S Q+MN+ LAE S  + +  + + AL E+++++ +Y ++I+  L+ D    K +L
Sbjct: 1832 QSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQL 1891

Query: 1880 AYKLEQVITLM 1890
            A +L+QV  L+
Sbjct: 1892 ACRLQQVAALV 1902


>gi|157694524 plexin D1 [Homo sapiens]
          Length = 1925

 Score =  887 bits (2292), Expect = 0.0
 Identities = 626/1955 (32%), Positives = 952/1955 (48%), Gaps = 216/1955 (11%)

Query: 52   NHLVVDERTGHIYLGAVNRIYKLS-SDLKVLVTHETGPDEDNPKCYPPRIVQ-TCNEPLT 109
            N+  +D   G +YL AVNR+Y+LS ++L +      GP  D+P C+ P++ Q +C  P  
Sbjct: 60   NNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRR 119

Query: 110  TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
             T+N NK+L +D  +  ++ CGS+YQG C+L R  ++  +   +         V    S+
Sbjct: 120  LTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSM 179

Query: 170  FGVIVSYSNLD--------------DKLFIATAVDGKPEYF---------------PTIS 200
              V  ++ N                 +L +     G    F               P I+
Sbjct: 180  LNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIA 239

Query: 201  SRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLT-- 258
             R L    +   +F +  +          PSD      D  +    G    + + F++  
Sbjct: 240  IRSLDTRGDLAKLFTFDLN----------PSD------DNILKIKQGAKEQHKLGFVSAF 283

Query: 259  LQPEMVSPPGSTT--------------KEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSG 304
            L P    PPG+ +              KE    S L R+C    A     ++     + G
Sbjct: 284  LHPSD-PPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLG 342

Query: 305  VEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQIN 364
                 LQ A  +  G +  R + V P  + LF VF + Q         +ALC F    + 
Sbjct: 343  -----LQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVR 397

Query: 365  DRIKERLQSCYRGEGTLDLAWLKVKDI----PCSSALLTIDDNFCGLDMNA-----PLGV 415
              I+    +C+  E   D+  +    +    P     L I      LD  A     PL +
Sbjct: 398  AAIRAARTACFV-EPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSI 456

Query: 416  SDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQV 475
               ++  PVF      +TSV      N++  F+GT +G+L KI ++      +    V V
Sbjct: 457  LQPLKATPVFRAPG--LTSVAVASVNNYTAVFLGTVNGRLLKINLNESM-QVVSRRVVTV 513

Query: 476  VDPGPVLRDMAFSK-DHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHN 534
                PV   M F   D   LY+M+  Q+ RV V +C  + +CG+C+G+ D +CGWC L  
Sbjct: 514  AYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALET 573

Query: 535  TCTRKERCERSKEPRRFASEMK---QCVRLTVHPNNISVSQ-YNVLLVLETYNVPELSA- 589
             CT ++ C  S +   + S  +   +C  +TV P+ I V Q Y  +++  + ++P LS  
Sbjct: 574  RCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGM 633

Query: 590  GVNCTFED----LSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMT 645
             + C + +    ++ + G   G+QI   +   ++       N DH  V++ ++    G  
Sbjct: 634  EMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVRVN--GRN 691

Query: 646  FASTSFVFYNCS------VHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPE 699
                +F  Y+CS       H +C SC+ + + C WC  +H C  +   C         P+
Sbjct: 692  IVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNPTS-PQ 750

Query: 700  DCPQLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSS 759
            DCP+ L      VP    + I +   N    Q      EC     G E+   A+  N S 
Sbjct: 751  DCPRTLLSPLAPVPTGGSQNILVPLANTAFFQGA--ALECSF---GLEEIFEAVWVNESV 805

Query: 760  VQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCL-KAD 818
            V+C      +   +    P+ L +       +D+P    V +Y C      C  CL + D
Sbjct: 806  VRCDQVVL-HTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQCLGRED 864

Query: 819  PDFACGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTI 878
                C W  G   C LR            L      C  P I  I P++GP +GGT +TI
Sbjct: 865  LGHLCMWSDG---CRLRG----------PLQPMAGTCPAPEIRAIEPLSGPLDGGTLLTI 911

Query: 879  RGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCR 938
            RG NLG    D+A  V + GV C PL D Y  +E+IVC  G A P   +G V +  +   
Sbjct: 912  RGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPA-PGPLSGVVTVNASK-- 968

Query: 939  PEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGK-QPCLFH 997
                 +S   + ++   +  L+P+ GP +GGT++TI G +L+ GS + V+     PC   
Sbjct: 969  ---EGKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTEL 1025

Query: 998  RRSPSYIVCNTTSSDEVLEMKVSVQVDRAK-IHQDLVFQYVEDPTIVRIEPEWSIVSGNT 1056
             R+ + I C          + V V+ +R   +H +L F Y+++P I  I P  S VSG  
Sbjct: 1026 MRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGR 1085

Query: 1057 PIAVWGTHLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPE 1116
             I V G    ++QN  +   H G+E   +C+VLN+T +TC +P          D      
Sbjct: 1086 TITVAGERFHMVQNVSMAVHHIGREP-TLCKVLNSTLITCPSPGALSNASAPVDFFINGR 1144

Query: 1117 EFGFILDNVQSLLILNKTN------FTYYPNPVFEAFGPSGILELKPGTPIIL---KGKN 1167
             +   +   + LL   +          Y PNP F        ++  PG P+ L   K ++
Sbjct: 1145 AYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKEQD 1204

Query: 1168 LIPPVAGGNVKLNYTVLVGEKPCTVTVSDVQLLCESPN-----LIGRHKVMARVGGMEYS 1222
             +     G     Y V +G+  C + +   +++  S N      +G+  +  +VG    +
Sbjct: 1205 SL-----GLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQT 1259

Query: 1223 PGMVYIAPDSPLSLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLE 1282
               + +          IVSI +   LL++ +VA+ + +  KSR ++   ++  +QM+ +E
Sbjct: 1260 IATLQLGGSETA---IIVSIVICSVLLLLSVVALFV-FCTKSRRAERYWQKTLLQMEEME 1315

Query: 1283 SRVALECKEAFAELQTDIHELTSDLDGA-GIPFLDYRTYTMRVLFPGI------------ 1329
            S++  E ++ FAELQTD+ +LT +L+ + GIPFL+Y+ +  R  FP              
Sbjct: 1316 SQIREEIRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPS 1375

Query: 1330 ------------EDHPVLRDLEVPGYRQERVEKGLKLFAQLINNKVFLLSFIRTLESQRS 1377
                        E HP+L + ++P   +  +E+G+ LF+ L+NNK FL+ F+  LE Q+ 
Sbjct: 1376 QTLNSQGSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKD 1435

Query: 1378 FSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNHPKLLLRRTESVAEKM 1437
            F++RDR ++ASL+   L  KLEY T ++K+LL DLID +  +  +PKL+LRRTESV EKM
Sbjct: 1436 FAVRDRCSLASLLTIALHGKLEYYTSIMKELLVDLIDAS--AAKNPKLMLRRTESVVEKM 1493

Query: 1438 LTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDY 1497
            LTNW +  +Y  L+E  GEP F L CAIKQQ+ KG IDAITG+ARY+L+E+ L+R+ I+ 
Sbjct: 1494 LTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEA 1553

Query: 1498 KTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQ 1557
            K   L+ VS        + V+ ++ DT+TQVKEKIL+A  KNVP S  P+A D+DLEW  
Sbjct: 1554 KPRNLN-VSFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFA 1612

Query: 1558 GSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVA--LVSKQVTAYNAVNNSTVSR 1615
             S    IL+D D T+ +E+  K+LNTLAHY++P+G+ +A  L+ K+        ++T+ R
Sbjct: 1613 SSTQSYILRDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKK--------DNTLGR 1664

Query: 1616 TSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVKNHEHGDQKEGDRGSKMVSE 1675
                  E         D L                     K+H    +K      K++ E
Sbjct: 1665 VKDLDTEKYFHLVLPTDELAEPK-----------------KSHRQSHRK------KVLPE 1701

Query: 1676 IYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVR 1735
            IYLTRLL+TKGTLQKF+DDLF+ I S   R    PLA+KY FDFL+EQA+K GI DP   
Sbjct: 1702 IYLTRLLSTKGTLQKFLDDLFKAILSI--REDKPPLAVKYFFDFLEEQAEKRGISDPDTL 1759

Query: 1736 HTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPS 1795
            H WK+N LPLRFWVN++KNPQFVFDI K    DACLSV+AQ F+D+CS S+ +LGKDSP+
Sbjct: 1760 HIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPT 1819

Query: 1796 NKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFS 1855
            NKLLYAK+IP Y+  V+RYY  I  M  +S+Q+MNA+LAE+SR + NEFNT  A++EI+ 
Sbjct: 1820 NKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYK 1879

Query: 1856 YVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLM 1890
            Y  +Y  +I+  L+ +    + +L +K EQV+ LM
Sbjct: 1880 YAKRYRPQIMAALEANPTARRTQLQHKFEQVVALM 1914


>gi|194272180 plexin B1 [Homo sapiens]
          Length = 2135

 Score =  793 bits (2047), Expect = 0.0
 Identities = 482/1259 (38%), Positives = 694/1259 (55%), Gaps = 120/1259 (9%)

Query: 701  CPQLLRVD-KILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPAL------ 753
            CP +  V    L+PV V + I L  +NL   Q G    EC++ ++G E  V A       
Sbjct: 913  CPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPP 972

Query: 754  RFNSSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGL 813
                  V CQ    SYE ++   L V L +   G   +D+     V LY C      C  
Sbjct: 973  PDTQCHVTCQQHQLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSR 1031

Query: 814  CLKADPDFACGWCQGPG-QCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREG 872
            C  A P + C WC+G   +C  R+ C   E+         ++C  P I  + P+TGP +G
Sbjct: 1032 CQTAMPQYGCVWCEGERPRCVTREACGEAEA-------VATQCPAPLIHSVEPLTGPVDG 1084

Query: 873  GTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEI 932
            GT+VTIRG NLG   +D+   V VAGV C+     Y  +  +VC  G A   + AG   +
Sbjct: 1085 GTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITG-ASGEEVAGATAV 1143

Query: 933  CVAVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAG--SNVVVMFG 990
             V          S   + +    +  + P+RGP +GGT++T+ G+ L  G   ++ V+ G
Sbjct: 1144 EVP---GRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200

Query: 991  KQPC-LFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAKIH-QDLVFQYVEDPTIVRIEPE 1048
             QPC L   +    + C T+       + V+V     +   Q   F+Y  DP I    P 
Sbjct: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260

Query: 1049 WSIVSGNTPIAVWGTHLDLIQNPQIRA-----------------------------KHGG 1079
             S +SG   I V G +LD++Q P+IR                                  
Sbjct: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320

Query: 1080 KEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDN-VQSLLILNKTNFTY 1138
            ++    C V ++  +TC+ PAL   P    D   R E   FILDN V     LN T F+Y
Sbjct: 1321 QQFEEPCHVNSSQLITCRTPAL---PGLPEDPWVRVE---FILDNLVFDFATLNPTPFSY 1374

Query: 1139 YPNPVFEAFGPSGI---LELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKPCTV-TV 1194
              +P  +   P         KPG+   ++G+NL   ++    K     ++G+ PC V T+
Sbjct: 1375 EADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMS----KEEVVAMIGDGPCVVKTL 1430

Query: 1195 SDVQLLCESP--NLIGRHKVM-----------ARVGGMEYSPGMVYIAPDSPLSLP--AI 1239
            +   L CE P    + RH  +            ++G + +S G V    +SP + P  A 
Sbjct: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQ 1490

Query: 1240 VSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTD 1299
            V + V   LL + ++ +++ Y+RKS+++    K++Q+Q++NLES V   CK+ F +L T+
Sbjct: 1491 VGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTE 1550

Query: 1300 IHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLI 1359
            + +LTSDL G+GIPFLDY+ Y  R+ FPG  + P+ RDL VP  R+  VE+GL   + L+
Sbjct: 1551 MTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLL 1610

Query: 1360 NNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLES 1419
            N+K+FL  FI TLESQR+FS RDR  VASL+   L  KLEY TD+L+ LL+DL+ + + +
Sbjct: 1611 NSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-A 1669

Query: 1420 KNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITG 1479
            KN PKL+LRRTE+V EK+LTNW +  LY F+++  GEPL+ LF  IK Q++KGP+D++TG
Sbjct: 1670 KN-PKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTG 1728

Query: 1480 EARYSLSEDKLIRQQIDYKTLVLSC---VSPDNANSPEVPVKILNCDTITQVKEKILDAI 1536
            +A+Y+L++++L+R+ ++Y+ L L+    V P    +  VPVK+L+CDTI+Q KEK+LD +
Sbjct: 1729 KAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQL 1788

Query: 1537 FKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVA 1596
            +K VP + RP    +D+EWR G    +IL DED+T++++  W+RLNTL HY+VPDG+ VA
Sbjct: 1789 YKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVA 1848

Query: 1597 LVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVK 1656
            LV                 T     EN     G       RTPM+    E G++ WHLVK
Sbjct: 1849 LVP--------------CLTKHVLRENQDYVPGE------RTPMLEDVDEGGIRPWHLVK 1888

Query: 1657 NHEHGDQKEGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGS 1707
              +  +     RGS         K + EIYLTRLL+ KGTLQKFVDDLF+ I ST+    
Sbjct: 1889 PSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR--- 1945

Query: 1708 ALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSIT 1767
             +PLA+KY FD LDEQA +HGI D    H WK+N LPLRFW+N+IKNPQFVFD+  +   
Sbjct: 1946 PVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNM 2005

Query: 1768 DACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQ 1827
            DA L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK  VERYY+DI +    SDQ
Sbjct: 2006 DAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQ 2065

Query: 1828 DMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQV 1886
            +MN+ LAE S  +  +     AL E++ Y+ KY ++I+  L+ D    K +L Y+L+Q+
Sbjct: 2066 EMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQI 2124



 Score =  238 bits (607), Expect = 4e-62
 Identities = 182/663 (27%), Positives = 310/663 (46%), Gaps = 69/663 (10%)

Query: 53  HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
           HL  D  +G +YLGA N +++LS  L++  T  TGP  D+  C PP +   C +    TN
Sbjct: 37  HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQA-QPTN 95

Query: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLG-EPYHKKE-HYLSGVNESGSVF 170
           N N++LL+      L+ CGS++QG+C+  RL  L +L   P    +  Y++  + + S  
Sbjct: 96  NPNQLLLVS--PGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153

Query: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228
           G++      +  LF+       G     P I++R L      D   A+ + +    ++ +
Sbjct: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALWP---PDPQAAFSYEETAKLAVGR 210

Query: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288
           +         ++  ++V  F+ G   YFL L+ ++ +      + + + + + R+C  D 
Sbjct: 211 LS--------EYSHHFVSAFARGASAYFLFLRRDLQA------QSRAFRAYVSRVCLRDQ 256

Query: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMK 348
            + SYVE+P+ CE  G  Y L+QAA ++ +  V           ++LF  FS      + 
Sbjct: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREVA--------HGEVLFAAFSSAAPPTVG 306

Query: 349 --------SLDESALCIFILKQINDRIKERLQSCYRGEGTLD----LAWLKVKDIPCSSA 396
                   +   SALC F L +++        +CY  EG  +    +A+++  D+    A
Sbjct: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365

Query: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452
            L   T+D   CG D   +P+     +   P+      ++T+V   +   H++AF+G   
Sbjct: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425

Query: 453 GKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQ 512
           G+L ++ + GP  +   Y T  +     V RD+ F    E LY+M++  L +VPV SC Q
Sbjct: 426 GQLHRVYL-GPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQ 484

Query: 513 YQSCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRR----FASEMKQCVRLTVHPNNI 568
           +  C  CL   DP+CGWCVL   C+R+  C R + P +    F  E+       + P NI
Sbjct: 485 HLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANI 544

Query: 569 SVSQYNVLLVLETYNVPELSAG--VNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITE 626
           S  +   +  L   ++P L  G   +C F +  +   L+ G+ + C SP   E P ++  
Sbjct: 545 SREETREVF-LSVPDLPPLWPGESYSCHFGE-HQSPALLTGSGVMCPSPDPSEAP-VLPR 601

Query: 627 NGDHHVVQLQLKSKETGMTFASTSFVFYNCSV------HNSCLSCVESPYRCHWCKYRHV 680
             D+  V ++L+     +  A TS  FY+C           C +CV S + C+WC ++H+
Sbjct: 602 GADYVSVSVELRF--GAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHL 659

Query: 681 CTH 683
           CTH
Sbjct: 660 CTH 662



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 52/204 (25%), Positives = 78/204 (38%), Gaps = 34/204 (16%)

Query: 655 NCSVHNSCLSCV--ESPYRCHWCKYRHVCTHDPKTCSFQEGRVKL-----PE-DCPQLLR 706
           +C+ H  C SC+    PY C WC     C+   + CS  +G  +      PE  C Q+  
Sbjct: 481 SCAQHLDCASCLAHRDPY-CGWCVLLGRCSRRSE-CSRGQGPEQWLWSFQPELGCLQVAA 538

Query: 707 VDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQCQNTS 766
           +    +  E  + + L   +LP    G+  Y C       E + PAL    S V C +  
Sbjct: 539 MSPANISREETREVFLSVPDLPPLWPGE-SYSCHFG----EHQSPAL-LTGSGVMCPSPD 592

Query: 767 YSY-----EGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRE-----SCGLCLK 816
            S       G +  ++ VEL       F     A+  +  Y C A+ E      C  C+ 
Sbjct: 593 PSEAPVLPRGADYVSVSVEL------RFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVS 646

Query: 817 ADPDFACGWCQGPGQCTLRQHCPA 840
           +   + C WC     CT +  C A
Sbjct: 647 SR--WGCNWCVWQHLCTHKASCDA 668



 Score = 35.0 bits (79), Expect = 0.70
 Identities = 45/178 (25%), Positives = 72/178 (40%), Gaps = 28/178 (15%)

Query: 798 KVHLYKCGAMRESCGLCLKADPDFACGWCQGPGQCTLRQHCPAQE--SQWLELSGAKSKC 855
           KV +  C A    C  CL A  D  CGWC   G+C+ R  C   +   QWL     +  C
Sbjct: 476 KVPVASC-AQHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGC 533

Query: 856 TNPRITEIIPVTGPREGGTKVTIR---------GENLGLEFRDIASHVKV--AGVECSPL 904
              ++  + P    RE   +V +          GE+    F +  S   +  +GV C P 
Sbjct: 534 L--QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMC-PS 590

Query: 905 VDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLKPS 962
            D   P+E  V   G       A +V + V +     +   + L ++  + +++L+PS
Sbjct: 591 PD---PSEAPVLPRG-------ADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPS 638


>gi|40254442 plexin B1 [Homo sapiens]
          Length = 2135

 Score =  793 bits (2047), Expect = 0.0
 Identities = 482/1259 (38%), Positives = 694/1259 (55%), Gaps = 120/1259 (9%)

Query: 701  CPQLLRVD-KILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPAL------ 753
            CP +  V    L+PV V + I L  +NL   Q G    EC++ ++G E  V A       
Sbjct: 913  CPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEVVVEARVECEPP 972

Query: 754  RFNSSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGL 813
                  V CQ    SYE ++   L V L +   G   +D+     V LY C      C  
Sbjct: 973  PDTQCHVTCQQHQLSYEALQ-PELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSR 1031

Query: 814  CLKADPDFACGWCQGPG-QCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREG 872
            C  A P + C WC+G   +C  R+ C   E+         ++C  P I  + P+TGP +G
Sbjct: 1032 CQTAMPQYGCVWCEGERPRCVTREACGEAEA-------VATQCPAPLIHSVEPLTGPVDG 1084

Query: 873  GTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEI 932
            GT+VTIRG NLG   +D+   V VAGV C+     Y  +  +VC  G A   + AG   +
Sbjct: 1085 GTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITG-ASGEEVAGATAV 1143

Query: 933  CVAVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAG--SNVVVMFG 990
             V          S   + +    +  + P+RGP +GGT++T+ G+ L  G   ++ V+ G
Sbjct: 1144 EVP---GRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVG 1200

Query: 991  KQPC-LFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAKIH-QDLVFQYVEDPTIVRIEPE 1048
             QPC L   +    + C T+       + V+V     +   Q   F+Y  DP I    P 
Sbjct: 1201 DQPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPT 1260

Query: 1049 WSIVSGNTPIAVWGTHLDLIQNPQIRA-----------------------------KHGG 1079
             S +SG   I V G +LD++Q P+IR                                  
Sbjct: 1261 KSFLSGGREICVRGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSS 1320

Query: 1080 KEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDN-VQSLLILNKTNFTY 1138
            ++    C V ++  +TC+ PAL   P    D   R E   FILDN V     LN T F+Y
Sbjct: 1321 QQFEEPCHVNSSQLITCRTPAL---PGLPEDPWVRVE---FILDNLVFDFATLNPTPFSY 1374

Query: 1139 YPNPVFEAFGPSGI---LELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKPCTV-TV 1194
              +P  +   P         KPG+   ++G+NL   ++    K     ++G+ PC V T+
Sbjct: 1375 EADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMS----KEEVVAMIGDGPCVVKTL 1430

Query: 1195 SDVQLLCESP--NLIGRHKVM-----------ARVGGMEYSPGMVYIAPDSPLSLP--AI 1239
            +   L CE P    + RH  +            ++G + +S G V    +SP + P  A 
Sbjct: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQ 1490

Query: 1240 VSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTD 1299
            V + V   LL + ++ +++ Y+RKS+++    K++Q+Q++NLES V   CK+ F +L T+
Sbjct: 1491 VGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTE 1550

Query: 1300 IHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLI 1359
            + +LTSDL G+GIPFLDY+ Y  R+ FPG  + P+ RDL VP  R+  VE+GL   + L+
Sbjct: 1551 MTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVPESRRPTVEQGLGQLSNLL 1610

Query: 1360 NNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLES 1419
            N+K+FL  FI TLESQR+FS RDR  VASL+   L  KLEY TD+L+ LL+DL+ + + +
Sbjct: 1611 NSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYV-A 1669

Query: 1420 KNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITG 1479
            KN PKL+LRRTE+V EK+LTNW +  LY F+++  GEPL+ LF  IK Q++KGP+D++TG
Sbjct: 1670 KN-PKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTG 1728

Query: 1480 EARYSLSEDKLIRQQIDYKTLVLSC---VSPDNANSPEVPVKILNCDTITQVKEKILDAI 1536
            +A+Y+L++++L+R+ ++Y+ L L+    V P    +  VPVK+L+CDTI+Q KEK+LD +
Sbjct: 1729 KAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAKEKMLDQL 1788

Query: 1537 FKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVA 1596
            +K VP + RP    +D+EWR G    +IL DED+T++++  W+RLNTL HY+VPDG+ VA
Sbjct: 1789 YKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVA 1848

Query: 1597 LVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLVK 1656
            LV                 T     EN     G       RTPM+    E G++ WHLVK
Sbjct: 1849 LVP--------------CLTKHVLRENQDYVPGE------RTPMLEDVDEGGIRPWHLVK 1888

Query: 1657 NHEHGDQKEGDRGS---------KMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGS 1707
              +  +     RGS         K + EIYLTRLL+ KGTLQKFVDDLF+ I ST+    
Sbjct: 1889 PSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSR--- 1945

Query: 1708 ALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSIT 1767
             +PLA+KY FD LDEQA +HGI D    H WK+N LPLRFW+N+IKNPQFVFD+  +   
Sbjct: 1946 PVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNM 2005

Query: 1768 DACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQ 1827
            DA L V+AQTFMD+C+ ++H+LG+DSP NKLLYA+DIP YK  VERYY+DI +    SDQ
Sbjct: 2006 DAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQ 2065

Query: 1828 DMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQV 1886
            +MN+ LAE S  +  +     AL E++ Y+ KY ++I+  L+ D    K +L Y+L+Q+
Sbjct: 2066 EMNSVLAELSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQI 2124



 Score =  238 bits (607), Expect = 4e-62
 Identities = 182/663 (27%), Positives = 310/663 (46%), Gaps = 69/663 (10%)

Query: 53  HLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTTN 112
           HL  D  +G +YLGA N +++LS  L++  T  TGP  D+  C PP +   C +    TN
Sbjct: 37  HLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQA-QPTN 95

Query: 113 NVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLG-EPYHKKE-HYLSGVNESGSVF 170
           N N++LL+      L+ CGS++QG+C+  RL  L +L   P    +  Y++  + + S  
Sbjct: 96  NPNQLLLVS--PGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTV 153

Query: 171 GVIVSYSNLDDKLFIATAVD--GKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIK 228
           G++      +  LF+       G     P I++R L      D   A+ + +    ++ +
Sbjct: 154 GLVAQGLAGEPLLFVGRGYTSRGVGGGIPPITTRALWP---PDPQAAFSYEETAKLAVGR 210

Query: 229 IPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDT 288
           +         ++  ++V  F+ G   YFL L+ ++ +      + + + + + R+C  D 
Sbjct: 211 LS--------EYSHHFVSAFARGASAYFLFLRRDLQA------QSRAFRAYVSRVCLRDQ 256

Query: 289 AFNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMK 348
            + SYVE+P+ CE  G  Y L+QAA ++ +  V           ++LF  FS      + 
Sbjct: 257 HYYSYVELPLACE--GGRYGLIQAAAVATSREVA--------HGEVLFAAFSSAAPPTVG 306

Query: 349 --------SLDESALCIFILKQINDRIKERLQSCYRGEGTLD----LAWLKVKDIPCSSA 396
                   +   SALC F L +++        +CY  EG  +    +A+++  D+    A
Sbjct: 307 RPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEY-DVNSDCA 365

Query: 397 LL---TIDDNFCGLDMN-APLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKS 452
            L   T+D   CG D   +P+     +   P+      ++T+V   +   H++AF+G   
Sbjct: 366 QLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQ 425

Query: 453 GKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQ 512
           G+L ++ + GP  +   Y T  +     V RD+ F    E LY+M++  L +VPV SC Q
Sbjct: 426 GQLHRVYL-GPGSDGHPYSTQSIQQGSAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQ 484

Query: 513 YQSCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRR----FASEMKQCVRLTVHPNNI 568
           +  C  CL   DP+CGWCVL   C+R+  C R + P +    F  E+       + P NI
Sbjct: 485 HLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANI 544

Query: 569 SVSQYNVLLVLETYNVPELSAG--VNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIITE 626
           S  +   +  L   ++P L  G   +C F +  +   L+ G+ + C SP   E P ++  
Sbjct: 545 SREETREVF-LSVPDLPPLWPGESYSCHFGE-HQSPALLTGSGVMCPSPDPSEAP-VLPR 601

Query: 627 NGDHHVVQLQLKSKETGMTFASTSFVFYNCSV------HNSCLSCVESPYRCHWCKYRHV 680
             D+  V ++L+     +  A TS  FY+C           C +CV S + C+WC ++H+
Sbjct: 602 GADYVSVSVELRF--GAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHL 659

Query: 681 CTH 683
           CTH
Sbjct: 660 CTH 662



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 52/204 (25%), Positives = 78/204 (38%), Gaps = 34/204 (16%)

Query: 655 NCSVHNSCLSCV--ESPYRCHWCKYRHVCTHDPKTCSFQEGRVKL-----PE-DCPQLLR 706
           +C+ H  C SC+    PY C WC     C+   + CS  +G  +      PE  C Q+  
Sbjct: 481 SCAQHLDCASCLAHRDPY-CGWCVLLGRCSRRSE-CSRGQGPEQWLWSFQPELGCLQVAA 538

Query: 707 VDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSSVQCQNTS 766
           +    +  E  + + L   +LP    G+  Y C       E + PAL    S V C +  
Sbjct: 539 MSPANISREETREVFLSVPDLPPLWPGE-SYSCHFG----EHQSPAL-LTGSGVMCPSPD 592

Query: 767 YSY-----EGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRE-----SCGLCLK 816
            S       G +  ++ VEL       F     A+  +  Y C A+ E      C  C+ 
Sbjct: 593 PSEAPVLPRGADYVSVSVEL------RFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVS 646

Query: 817 ADPDFACGWCQGPGQCTLRQHCPA 840
           +   + C WC     CT +  C A
Sbjct: 647 SR--WGCNWCVWQHLCTHKASCDA 668



 Score = 35.0 bits (79), Expect = 0.70
 Identities = 45/178 (25%), Positives = 72/178 (40%), Gaps = 28/178 (15%)

Query: 798 KVHLYKCGAMRESCGLCLKADPDFACGWCQGPGQCTLRQHCPAQE--SQWLELSGAKSKC 855
           KV +  C A    C  CL A  D  CGWC   G+C+ R  C   +   QWL     +  C
Sbjct: 476 KVPVASC-AQHLDCASCL-AHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGC 533

Query: 856 TNPRITEIIPVTGPREGGTKVTIR---------GENLGLEFRDIASHVKV--AGVECSPL 904
              ++  + P    RE   +V +          GE+    F +  S   +  +GV C P 
Sbjct: 534 L--QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMC-PS 590

Query: 905 VDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLKPS 962
            D   P+E  V   G       A +V + V +     +   + L ++  + +++L+PS
Sbjct: 591 PD---PSEAPVLPRG-------ADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPS 638


>gi|5032223 plexin C1 [Homo sapiens]
          Length = 1568

 Score =  423 bits (1088), Expect = e-118
 Identities = 313/966 (32%), Positives = 490/966 (50%), Gaps = 110/966 (11%)

Query: 956  LSDLKPSRGPMSGGTQVTITGTNLNAGSNV-VVMFGKQPC------LFHRRSPSYIVCNT 1008
            +  ++P +    G + V +TG N    SN+ +++ G   C      + H  + +++  + 
Sbjct: 664  IKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSL 723

Query: 1009 TSSDEVLEMK-VSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDL 1067
             SS +  EMK V +Q D           Y+  P    I P  + +SG   I + G + D+
Sbjct: 724  PSSRK--EMKDVCIQFDGGNCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDV 781

Query: 1068 IQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQS 1127
            I N  I   H  K +IN+ E   AT     AP+L                   +  NV  
Sbjct: 782  IDNLII--SHELKGNINVSEYCVATYCGFLAPSLKSSK---------------VRTNVTV 824

Query: 1128 LLILNKT-----NFTYYPNPVFEAFGPSGILELKPGTPIILKGKNL--------IPPVAG 1174
             L +  T        Y  +P F  +     ++ +    I  +  N         I    G
Sbjct: 825  KLRVQDTYLDCGTLQYREDPRFTGYRVESEVDTELEVKIQKENDNFNISKKDIEITLFHG 884

Query: 1175 GNVKLN--YTVLVGEKPCTVTVSDVQLLCESPNLIGRHK-VMARVGGMEYSPGMVYIAPD 1231
             N +LN  +  +   +  T  +  ++ +  +  +    K V  ++G +E     +Y+  +
Sbjct: 885  ENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSSKKVRVKLGNLE-----LYVEQE 939

Query: 1232 S-PLSLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECK 1290
            S P +   ++ + V   LL+I I A +   + KS+E  L+ K+ Q Q++ LES +  E +
Sbjct: 940  SVPSTWYFLIVLPV---LLVIVIFAAVGVTRHKSKE--LSRKQSQ-QLELLESELRKEIR 993

Query: 1291 EAFAELQTDIHELTSDLDGAGIPFLDYRTYTMRVLFP--GIEDHPVLRDLEVPGYRQERV 1348
            + FAELQ D  ++        +PFLDY+ + +R  FP  G   H    D+    + ++  
Sbjct: 994  DGFAELQMDKLDVVDSF--GTVPFLDYKHFALRTFFPESGGFTHIFTEDM----HNRDAN 1047

Query: 1349 EKGLKLFA--QLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLK 1406
            +K   L A   LI NK FL++ I TLE Q++FS++DR   AS +   LQ+KL Y T +L+
Sbjct: 1048 DKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFASFLTIALQTKLVYLTSILE 1107

Query: 1407 QLLADLIDKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIK 1466
             L  DL+++   S   PKL+LRRTESV EK+LTNW +  L  FL+E  GEP + L   + 
Sbjct: 1108 VLTRDLMEQC--SNMQPKLMLRRTESVVEKLLTNWMSVCLSGFLRETVGEPFYLLVTTLN 1165

Query: 1467 QQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLVLSCVS---PDNANSP---EVPVKIL 1520
            Q++ KGP+D IT +A Y+L+ED L+ Q  ++ T+ L+ V    P+N ++     + V +L
Sbjct: 1166 QKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVFEKIPENESADVCRNISVNVL 1225

Query: 1521 NCDTITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKR 1580
            +CDTI Q KEKI  A        +  +  ++ LE + G+  + +L  +  +  +E+   +
Sbjct: 1226 DCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTRQKELLDIDSSSVILEDGITK 1285

Query: 1581 LNTLAHYQVPDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPM 1640
            LNT+ HY++ +GS + +  K                       +  +T   +       +
Sbjct: 1286 LNTIGHYEISNGSTIKVFKK-----------------------IANFTSDVEYSDDHCHL 1322

Query: 1641 ITPDLESGVKMWHLVKNHEHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIF 1700
            I PD E+   +         G +  G    K V E+YLT+LL+TK  +   ++ LF +I+
Sbjct: 1323 ILPDSEAFQDV--------QGKRHRGKHKFK-VKEMYLTKLLSTKVAIHSVLEKLFRSIW 1373

Query: 1701 STAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFD 1760
            S  +  S  P AIKY FDFLD QA+   I DP V H WK+N LPLRFWVN++KNPQFVFD
Sbjct: 1374 SLPN--SRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFD 1431

Query: 1761 IHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGK 1820
            I K    D CLSV+AQ FMD+ S +E +LGK++P+NKLLYAKDIP+YK  V+ YY  I  
Sbjct: 1432 IKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRD 1491

Query: 1821 MPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHD---DQCGKQ 1877
            +P +S  +M  +L ++S+ H NEFN   AL+EI+ Y+ KY +EIL  L+ +   ++  KQ
Sbjct: 1492 LPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQ 1551

Query: 1878 KLAYKL 1883
             L  K+
Sbjct: 1552 LLHVKV 1557



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 90/377 (23%), Positives = 149/377 (39%), Gaps = 52/377 (13%)

Query: 333 DLLFTVFSK--GQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAW-LKVK 389
           D+   VFS   G+ ++ +S   +ALC+F + +I  R K              ++W  K  
Sbjct: 304 DVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKR-------------VSWDFKTA 350

Query: 390 DIPCSSALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVG 449
           +  C                       + V+ I   T     +TSV   V  N ++ F+G
Sbjct: 351 ESHCKEG-----------------DQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLG 393

Query: 450 TKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSK-DHEQLYIMSERQLTRVPVE 508
           T  G+L K+ +     +       ++ +  PV   +      +  +Y+ + +++ R+ V 
Sbjct: 394 TGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVRRIRVA 453

Query: 509 SCGQYQSCGECLGSGDPHCGWCVLHNTCTRKERCERSKEPRRF---ASEMKQCVRLTVHP 565
           +C +++SC ECL + DPHCGWC     CT +  C  S+    +   +S  K+C ++ +  
Sbjct: 454 NCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQI-- 511

Query: 566 NNISVSQYNVLLVLETYNVPELSAGVNCTFEDLSEMDGLVVGNQIQCYSPAAKEVPRIIT 625
             I  S+    + +     P  S    C  +++     L   N+ Q        +P   T
Sbjct: 512 --IRSSKEKTTVTMVGSFSPRHS---KCMVKNVDSSREL-CQNKSQPNRTCTCSIPTRAT 565

Query: 626 ENGDHHVVQLQLKSKETGMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDP 685
              D  VV +       G    S  F F NCS    C +CVE+   C WCK    C H P
Sbjct: 566 YK-DVSVVNVMF---SFGSWNLSDRFNFTNCSSLKECPACVET--GCAWCKSARRCIH-P 618

Query: 686 KTCSFQEGRVKLPEDCP 702
            T        +  E CP
Sbjct: 619 FTACDPSDYERNQEQCP 635



 Score = 40.0 bits (92), Expect = 0.022
 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 809 ESCGLCLKADPDFACGWCQGPGQCTLRQHCPAQES--QWLELSGAKSKCTNPRI 860
           +SC  CL A  D  CGWC    +CT +  C   E+   WL++S    KC   +I
Sbjct: 459 KSCSECLTAT-DPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQI 511



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 37/184 (20%), Positives = 72/184 (39%), Gaps = 28/184 (15%)

Query: 655 NCSVHNSCLSCV-ESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPEDCPQLLRVD---KI 710
           NC+ H SC  C+  +   C WC       H  + C+FQ G     E+    L +    K 
Sbjct: 454 NCNKHKSCSECLTATDPHCGWC-------HSLQRCTFQ-GDCVHSENLENWLDISSGAKK 505

Query: 711 LVPVEVIKPITLKAKNLPQPQSGQRGYECIL-NIQGSEQRVPALRFNSSSVQCQ-NTSYS 768
              +++I+    K           R  +C++ N+  S +        + +  C   T  +
Sbjct: 506 CPKIQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVDSSRELCQNKSQPNRTCTCSIPTRAT 565

Query: 769 YEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLKADPDFACGWCQG 828
           Y+ + + N+         G +N+     ++ +   C +++E C  C++      C WC+ 
Sbjct: 566 YKDVSVVNVMFSF-----GSWNL----SDRFNFTNCSSLKE-CPACVET----GCAWCKS 611

Query: 829 PGQC 832
             +C
Sbjct: 612 ARRC 615


>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
          Length = 1390

 Score =  156 bits (395), Expect = 2e-37
 Identities = 140/534 (26%), Positives = 251/534 (47%), Gaps = 96/534 (17%)

Query: 62  HIYLGAVNRIYKLSS-DLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTT-----NNVN 115
           HI+LGA N IY L+  DL+ +  ++TGP  ++P C+P    Q C+     +     +N+N
Sbjct: 61  HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP---CQDCSSKANLSGGVWKDNIN 117

Query: 116 KMLLID-YKENRLIACGSLYQGICKL------------LRLEDLF--KLGEPYHKKEHYL 160
             L++D Y +++LI+CGS+ +G C+               +  +F  ++ EP    +  +
Sbjct: 118 MALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVV 177

Query: 161 SGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFP-----TISSRKLTKNSEADGMFA 215
           S +        V+ S  +     F+   ++    YFP     +IS R+L +  +    F 
Sbjct: 178 SALGAK-----VLSSVKDRFINFFVGNTINSS--YFPDHPLHSISVRRLKETKDG---FM 227

Query: 216 YVFHDEFVASMIKIPSDTFTIIPDF----DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTT 271
           ++    ++            ++P+F     I YV+ F S NF+YFLT+Q E       T 
Sbjct: 228 FLTDQSYI-----------DVLPEFRDSYPIKYVHAFESNNFIYFLTVQRE-------TL 269

Query: 272 KEQVYTSKLVRLCKEDTAFNSYVEVPIGC-------ERSGVE--YRLLQAAYLSKAGAVL 322
             Q + ++++R C  ++  +SY+E+P+ C       +RS  +  + +LQAAY+SK GA L
Sbjct: 270 DAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQL 329

Query: 323 GRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRI-----KERLQSCYRG 377
            R +G   +DD+LF VF++ +    + +D SA+C F +K +ND       K  ++     
Sbjct: 330 ARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHF 389

Query: 378 EGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIA 437
            G           +  SS      D +   +    L   D+  G   F+E    +TS+  
Sbjct: 390 YGPNHEHCFNRTLLRNSSGCEARRDEY-RTEFTTALQRVDLFMG--QFSE--VLLTSIST 444

Query: 438 YVYKNHSLAFVGTKSGKLKKIRV--DGPRGNALQYETVQVVDPGPVLRDMAFSKDHEQ-- 493
           ++  + ++A +GT  G+  ++ V   GP    + +    ++D  PV  ++       Q  
Sbjct: 445 FIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNF----LLDSHPVSPEVIVEHTLNQNG 500

Query: 494 -LYIMSERQLTRVPVE--SCGQYQSCGECLGSGDP--HCGWCVLHNTCTRKERC 542
              +++ +++T++P+    C  +QSC +CL S  P   CGWC  H+ C R E C
Sbjct: 501 YTLVITGKKITKIPLNGLGCRHFQSCSQCL-SAPPFVQCGWC--HDKCVRSEEC 551



 Score =  128 bits (322), Expect = 5e-29
 Identities = 147/624 (23%), Positives = 254/624 (40%), Gaps = 60/624 (9%)

Query: 735  RGYECILNIQGSEQRVPALRFNSSSVQCQNTSYSYEGMEIN-NLPVELTVVWNGH-FNID 792
            +G   I N+  SE R   +  + S     + ++  +   ++  + VE T+  NG+   I 
Sbjct: 447  KGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVIT 506

Query: 793  NPAQNKVHLYKCGAMR-ESCGLCLKADPDFACGWCQGPGQCTLRQHCPAQESQWLELSGA 851
                 K+ L   G    +SC  CL A P   CGWC    +C   + C         LSG 
Sbjct: 507  GKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHD--KCVRSEEC---------LSGT 555

Query: 852  -KSKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFR---DIASHVKVAGVECSPLVDG 907
               +   P I ++ P + P EGGT++TI G + G       D+     + G E   L   
Sbjct: 556  WTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLS 615

Query: 908  YIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMS 967
                  + C +G   P+ +  F  + + +       + S   Y +   ++ + P  GPM+
Sbjct: 616  ESTMNTLKCTVG---PAMNKHF-NMSIIISNGHGTTQYSTFSY-VDPVITSISPKYGPMA 670

Query: 968  GGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAK 1027
            GGT +T+TG  LN+G++  +  G + C     S S + C T +     E  V +++D A 
Sbjct: 671  GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN 730

Query: 1028 IHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQ--IRAKHGGKEHINI 1085
              +  +F Y EDP +  I P  S +SG + I   G +L+ +  P+  I     G+     
Sbjct: 731  -RETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVA 789

Query: 1086 CEVLNATE-MTCQAPALALGPDHQSDLTERPEEFGFILDNVQSLLILNKTNFTYYPNPVF 1144
            C+  + +E + C  P+L         L  + + F F+LD + S       +  Y  NPVF
Sbjct: 790  CQHRSNSEIICCTTPSL---QQLNLQLPLKTKAF-FMLDGILSKYF----DLIYVHNPVF 841

Query: 1145 EAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKPC-TVTVSDVQLLCES 1203
            + F    ++ +     + +KG ++ P    G V     + VG K C  + +    +LC  
Sbjct: 842  KPFEKPVMISMGNENVLEIKGNDIDPEAVKGEV-----LKVGNKSCENIHLHSEAVLCTV 896

Query: 1204 PN----LIGRHKVMARVGGMEYSPGMVYIAPDSPLS--LPAIVSIAVAGGLLIIFIVAVL 1257
            PN    L     +  +        G V + PD   +  +  +VSI+ A  LL+ F + + 
Sbjct: 897  PNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLK 956

Query: 1258 IAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHELTSDLDGAGIPFLDY 1317
               + K   S+L     ++   +L+  V+        E+ ++               +DY
Sbjct: 957  KRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSN-------------ESVDY 1003

Query: 1318 RTYTMRVLFPGIEDHPVLRDLEVP 1341
            R       FP    +   R ++ P
Sbjct: 1004 RATFPEDQFPNSSQNGSCRQVQYP 1027


>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
          Length = 1408

 Score =  156 bits (395), Expect = 2e-37
 Identities = 140/534 (26%), Positives = 251/534 (47%), Gaps = 96/534 (17%)

Query: 62  HIYLGAVNRIYKLSS-DLKVLVTHETGPDEDNPKCYPPRIVQTCNEPLTTT-----NNVN 115
           HI+LGA N IY L+  DL+ +  ++TGP  ++P C+P    Q C+     +     +N+N
Sbjct: 61  HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFP---CQDCSSKANLSGGVWKDNIN 117

Query: 116 KMLLID-YKENRLIACGSLYQGICKL------------LRLEDLF--KLGEPYHKKEHYL 160
             L++D Y +++LI+CGS+ +G C+               +  +F  ++ EP    +  +
Sbjct: 118 MALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVV 177

Query: 161 SGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFP-----TISSRKLTKNSEADGMFA 215
           S +        V+ S  +     F+   ++    YFP     +IS R+L +  +    F 
Sbjct: 178 SALGAK-----VLSSVKDRFINFFVGNTINSS--YFPDHPLHSISVRRLKETKDG---FM 227

Query: 216 YVFHDEFVASMIKIPSDTFTIIPDF----DIYYVYGFSSGNFVYFLTLQPEMVSPPGSTT 271
           ++    ++            ++P+F     I YV+ F S NF+YFLT+Q E       T 
Sbjct: 228 FLTDQSYI-----------DVLPEFRDSYPIKYVHAFESNNFIYFLTVQRE-------TL 269

Query: 272 KEQVYTSKLVRLCKEDTAFNSYVEVPIGC-------ERSGVE--YRLLQAAYLSKAGAVL 322
             Q + ++++R C  ++  +SY+E+P+ C       +RS  +  + +LQAAY+SK GA L
Sbjct: 270 DAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQL 329

Query: 323 GRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRI-----KERLQSCYRG 377
            R +G   +DD+LF VF++ +    + +D SA+C F +K +ND       K  ++     
Sbjct: 330 ARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHF 389

Query: 378 EGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIA 437
            G           +  SS      D +   +    L   D+  G   F+E    +TS+  
Sbjct: 390 YGPNHEHCFNRTLLRNSSGCEARRDEY-RTEFTTALQRVDLFMG--QFSE--VLLTSIST 444

Query: 438 YVYKNHSLAFVGTKSGKLKKIRV--DGPRGNALQYETVQVVDPGPVLRDMAFSKDHEQ-- 493
           ++  + ++A +GT  G+  ++ V   GP    + +    ++D  PV  ++       Q  
Sbjct: 445 FIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNF----LLDSHPVSPEVIVEHTLNQNG 500

Query: 494 -LYIMSERQLTRVPVE--SCGQYQSCGECLGSGDP--HCGWCVLHNTCTRKERC 542
              +++ +++T++P+    C  +QSC +CL S  P   CGWC  H+ C R E C
Sbjct: 501 YTLVITGKKITKIPLNGLGCRHFQSCSQCL-SAPPFVQCGWC--HDKCVRSEEC 551



 Score =  117 bits (293), Expect = 1e-25
 Identities = 147/642 (22%), Positives = 254/642 (39%), Gaps = 78/642 (12%)

Query: 735  RGYECILNIQGSEQRVPALRFNSSSVQCQNTSYSYEGMEIN-NLPVELTVVWNGH-FNID 792
            +G   I N+  SE R   +  + S     + ++  +   ++  + VE T+  NG+   I 
Sbjct: 447  KGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVIT 506

Query: 793  NPAQNKVHLYKCGAMR-ESCGLCLKADPDFACGWCQGPGQCTLRQHCPAQESQWLELSGA 851
                 K+ L   G    +SC  CL A P   CGWC    +C   + C         LSG 
Sbjct: 507  GKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHD--KCVRSEEC---------LSGT 555

Query: 852  -KSKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFR---DIASHVKVAGVECSPLVDG 907
               +   P I ++ P + P EGGT++TI G + G       D+     + G E   L   
Sbjct: 556  WTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLS 615

Query: 908  YIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMS 967
                  + C +G   P+ +  F  + + +       + S   Y +   ++ + P  GPM+
Sbjct: 616  ESTMNTLKCTVG---PAMNKHF-NMSIIISNGHGTTQYSTFSY-VDPVITSISPKYGPMA 670

Query: 968  GGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAK 1027
            GGT +T+TG  LN+G++  +  G + C     S S + C T +     E  V +++D A 
Sbjct: 671  GGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLAN 730

Query: 1028 IHQDLVFQYVEDPTIVRIEPEWSIV------------------SGNTPIAVWGTHLDLIQ 1069
              +  +F Y EDP +  I P  S +                  SG + I   G +L+ + 
Sbjct: 731  -RETSIFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVS 789

Query: 1070 NPQ--IRAKHGGKEHINICEVLNATE-MTCQAPALALGPDHQSDLTERPEEFGFILDNVQ 1126
             P+  I     G+     C+  + +E + C  P+L         L  + + F F+LD + 
Sbjct: 790  VPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSL---QQLNLQLPLKTKAF-FMLDGIL 845

Query: 1127 SLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVG 1186
            S       +  Y  NPVF+ F    ++ +     + +KG ++ P    G V     + VG
Sbjct: 846  SKYF----DLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEV-----LKVG 896

Query: 1187 EKPC-TVTVSDVQLLCESPN----LIGRHKVMARVGGMEYSPGMVYIAPDSPLS--LPAI 1239
             K C  + +    +LC  PN    L     +  +        G V + PD   +  +  +
Sbjct: 897  NKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGV 956

Query: 1240 VSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTD 1299
            VSI+ A  LL+ F + +    + K   S+L     ++   +L+  V+        E+ ++
Sbjct: 957  VSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSN 1016

Query: 1300 IHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVP 1341
                           +DYR       FP    +   R ++ P
Sbjct: 1017 -------------ESVDYRATFPEDQFPNSSQNGSCRQVQYP 1045


>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
           sapiens]
          Length = 1400

 Score =  103 bits (257), Expect = 2e-21
 Identities = 134/530 (25%), Positives = 215/530 (40%), Gaps = 73/530 (13%)

Query: 57  DERTGHIYLGAVNRIYKLSSDLKVLVTHETGPDEDNPKCYPPRIVQTC-------NEPLT 109
           D     +++   NR++ L  DLK + +  TGP  D P C      QTC       + P  
Sbjct: 64  DRNESAVFVAIRNRLHVLGPDLKSVQSLATGPAGD-PGC------QTCAACGPGPHGPPG 116

Query: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLED---LFKLGEP------YHKKEHYL 160
            T+   K+L++D     L++CGS  QG C L  LE       L  P      +H +    
Sbjct: 117 DTDT--KVLVLDPALPALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDC 174

Query: 161 SGVNESGSVFGVIVSYSNLDDKLFIATAVDGK--PEYFP-TISSRKLTKNSEADGMFAYV 217
                S     V V         ++A+++D      + P ++S R+L   ++A G     
Sbjct: 175 PDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRL--KADASG----- 227

Query: 218 FHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYT 277
           F   FVA  + +P      +  + I YV+ F +G FVYFLT+QP  V     T       
Sbjct: 228 FAPGFVALSV-LPKH----LVSYSIEYVHSFHTGAFVYFLTVQPASV-----TDDPSALH 277

Query: 278 SKLVRLCKEDTAFNSYVEVPIGCE-----------RSGVEYRLLQAAYLSKAGAVLGRTL 326
           ++L RL   +     Y E+ + C              G  Y +L+ A+ +  GA L   L
Sbjct: 278 TRLARLSATEPELGDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATEL 337

Query: 327 GVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWL 386
            +    ++LF VF  G+         S +C F +  ++  I E ++ C   E  +     
Sbjct: 338 SIAEGQEVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDEGVERCC--ESPVHPGLR 395

Query: 387 KVKDIPCSSALLTIDDNFCGLDMNA-----PLGVSDMVRGIPVFTEDRDRMTSVIAYVYK 441
           +  D   S +          L  N      PL VS     + +F      +     YV +
Sbjct: 396 RGLDFFQSPSFCPNPPGLEALSPNTSCRHFPLLVSSSFSRVDLFNGLLGPVQVTALYVTR 455

Query: 442 --NHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPG-PVLRDMAFSKDHEQLYIMS 498
             N ++A +GT  G++ ++ +       L      + D G PV RD++   DH  L   S
Sbjct: 456 LDNVTVAHMGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDVSRLGDH--LLFAS 513

Query: 499 ERQLTRVPVE--SCGQYQSCGECLGSGD-PHCGWCVLHNTCTRKERCERS 545
             Q+ +VP++   C  + +CG CL +     CGWC   N C +++ C  S
Sbjct: 514 GDQVFQVPIQGPGCRHFLTCGRCLRAWHFMGCGWC--GNMCGQQKECPGS 561



 Score =  100 bits (249), Expect = 1e-20
 Identities = 83/310 (26%), Positives = 131/310 (42%), Gaps = 34/310 (10%)

Query: 810  SCGLCLKADPDFACGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGP 869
            +CG CL+A     CGWC     C  ++ CP    Q          C  P++TE  P +GP
Sbjct: 532  TCGRCLRAWHFMGCGWCGN--MCGQQKECPGSWQQ--------DHCP-PKLTEFHPHSGP 580

Query: 870  REGGTKVTIRGENLGLEFRDIASH----VKVAGVECSPLVDGY-----IP----AEQIVC 916
              G T++T+ G N  L    +       V V    C PL         +P     E+  C
Sbjct: 581  LRGSTRLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFEC 640

Query: 917  EMGEAKPSQHAGFVEICVAVCR----PEFMARSSQL---YYFMTLTLSDLKPSRGPMSGG 969
            E+ E   +Q  G   + + V        F    + +   + FM   L  ++P  GP +GG
Sbjct: 641  EL-EPLGTQAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAGG 699

Query: 970  TQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAKIH 1029
            T +T+ G +L+ G++  V+     CL  R S   ++C T     V  + +S+QV  A++ 
Sbjct: 700  TCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQVP 759

Query: 1030 QDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIRAKHGGKEHINICEVL 1089
                FQY EDP ++ I P    +  N+ I + G HL    +  +    G +   + CE  
Sbjct: 760  GSWTFQYREDPVVLSISPNCGYI--NSHITICGQHLTSAWHLVLSFHDGLRAVESRCERQ 817

Query: 1090 NATEMTCQAP 1099
               +  C+ P
Sbjct: 818  LPEQQLCRLP 827


>gi|39777610 semaphorin 4B precursor [Homo sapiens]
          Length = 837

 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 150/681 (22%), Positives = 260/681 (38%), Gaps = 129/681 (18%)

Query: 11  LLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNR 70
           LL  LL     +  L  R   PL  ++R F+ F  E    +  L++      +Y+GA   
Sbjct: 30  LLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREA 89

Query: 71  IYKLSSDLKVLVTHET-----GPDEDNPKCYPPRIVQTCN----EPLTTTNNVNKMLLID 121
           ++ LSS+L  L   E      G D +          Q C+    +P     N  K+LL  
Sbjct: 90  LFALSSNLSFLPGGEYQELLWGADAEKK--------QQCSFKGKDPQRDCQNYIKILL-P 140

Query: 122 YKENRLIACGSL-YQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNL- 179
              + L  CG+  +  +C  + +E+ F L     +K + L    +    F      + L 
Sbjct: 141 LSGSHLFTCGTAAFSPMCTYINMEN-FTLARD--EKGNVLLEDGKGRCPFDPNFKSTALV 197

Query: 180 -DDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIP 238
            D +L+  T V       P IS  +  + ++ +    ++    FVAS   IP    ++  
Sbjct: 198 VDGELYTGT-VSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAY-IPESLGSLQG 255

Query: 239 DFD-IYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA-------- 289
           D D IY+ +  +   F +F                E    S++ R+CK D          
Sbjct: 256 DDDKIYFFFSETGQEFEFF----------------ENTIVSRIARICKGDEGGERVLQQR 299

Query: 290 FNSYVEVPIGCER--SGVEYRLLQAAYLSKAGAVLGRTLGVHPDD---DLLFTVFSKGQK 344
           + S+++  + C R   G  + +LQ  +          TL   P D    L + VF+    
Sbjct: 300 WTSFLKAQLLCSRPDDGFPFNVLQDVF----------TLSPSPQDWRDTLFYGVFTSQWH 349

Query: 345 RKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKD-IPCSSALLTIDDN 403
           R   + + SA+C+F +K +    +      Y+        W  V   +P       I ++
Sbjct: 350 RG--TTEGSAVCVFTMKDV----QRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNS 403

Query: 404 FCGLDMNAPLGVSD--------------MVRGIPVFTEDRDRMTSVIAY----VYKNHSL 445
                +N+ L + D               VR   +  + + R   V  +    ++  + +
Sbjct: 404 ARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDV 463

Query: 446 AFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRV 505
            F+GT  G+L K    GPR + +  E +Q+   G  ++++        LY  S   + +V
Sbjct: 464 LFLGTGDGRLHKAVSVGPRVHII--EELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQV 521

Query: 506 PVESCGQYQSCGECLGSGDPHCGWCVLHNTC----------------------TRKERCE 543
           P+ +C  Y+SCG+CL + DP+C W    ++C                      + K+ C 
Sbjct: 522 PMANCSLYRSCGDCLLARDPYCAWS--GSSCKHVSLYQPQLATRPWIQDIEGASAKDLCS 579

Query: 544 RSK--EPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLET----YNVPELSAGVNCTFED 597
            S    P    +  K C ++   PN ++     +L  L T     N   ++A  +C    
Sbjct: 580 ASSVVSPSFVPTGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASC--HV 637

Query: 598 LSEMDGLVVGNQ----IQCYS 614
           L   D L+VG Q     QC+S
Sbjct: 638 LPTGDLLLVGTQQLGEFQCWS 658


>gi|39777608 semaphorin 4B precursor [Homo sapiens]
          Length = 837

 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 150/681 (22%), Positives = 260/681 (38%), Gaps = 129/681 (18%)

Query: 11  LLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNR 70
           LL  LL     +  L  R   PL  ++R F+ F  E    +  L++      +Y+GA   
Sbjct: 30  LLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREA 89

Query: 71  IYKLSSDLKVLVTHET-----GPDEDNPKCYPPRIVQTCN----EPLTTTNNVNKMLLID 121
           ++ LSS+L  L   E      G D +          Q C+    +P     N  K+LL  
Sbjct: 90  LFALSSNLSFLPGGEYQELLWGADAEKK--------QQCSFKGKDPQRDCQNYIKILL-P 140

Query: 122 YKENRLIACGSL-YQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNL- 179
              + L  CG+  +  +C  + +E+ F L     +K + L    +    F      + L 
Sbjct: 141 LSGSHLFTCGTAAFSPMCTYINMEN-FTLARD--EKGNVLLEDGKGRCPFDPNFKSTALV 197

Query: 180 -DDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIP 238
            D +L+  T V       P IS  +  + ++ +    ++    FVAS   IP    ++  
Sbjct: 198 VDGELYTGT-VSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAY-IPESLGSLQG 255

Query: 239 DFD-IYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA-------- 289
           D D IY+ +  +   F +F                E    S++ R+CK D          
Sbjct: 256 DDDKIYFFFSETGQEFEFF----------------ENTIVSRIARICKGDEGGERVLQQR 299

Query: 290 FNSYVEVPIGCER--SGVEYRLLQAAYLSKAGAVLGRTLGVHPDD---DLLFTVFSKGQK 344
           + S+++  + C R   G  + +LQ  +          TL   P D    L + VF+    
Sbjct: 300 WTSFLKAQLLCSRPDDGFPFNVLQDVF----------TLSPSPQDWRDTLFYGVFTSQWH 349

Query: 345 RKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKD-IPCSSALLTIDDN 403
           R   + + SA+C+F +K +    +      Y+        W  V   +P       I ++
Sbjct: 350 RG--TTEGSAVCVFTMKDV----QRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNS 403

Query: 404 FCGLDMNAPLGVSD--------------MVRGIPVFTEDRDRMTSVIAY----VYKNHSL 445
                +N+ L + D               VR   +  + + R   V  +    ++  + +
Sbjct: 404 ARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDV 463

Query: 446 AFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRV 505
            F+GT  G+L K    GPR + +  E +Q+   G  ++++        LY  S   + +V
Sbjct: 464 LFLGTGDGRLHKAVSVGPRVHII--EELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQV 521

Query: 506 PVESCGQYQSCGECLGSGDPHCGWCVLHNTC----------------------TRKERCE 543
           P+ +C  Y+SCG+CL + DP+C W    ++C                      + K+ C 
Sbjct: 522 PMANCSLYRSCGDCLLARDPYCAWS--GSSCKHVSLYQPQLATRPWIQDIEGASAKDLCS 579

Query: 544 RSK--EPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLET----YNVPELSAGVNCTFED 597
            S    P    +  K C ++   PN ++     +L  L T     N   ++A  +C    
Sbjct: 580 ASSVVSPSFVPTGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASC--HV 637

Query: 598 LSEMDGLVVGNQ----IQCYS 614
           L   D L+VG Q     QC+S
Sbjct: 638 LPTGDLLLVGTQQLGEFQCWS 658


>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
          Length = 1151

 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 117/556 (21%), Positives = 225/556 (40%), Gaps = 110/556 (19%)

Query: 26  LTRQPAPLSQKQRSFVT-FRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLS-SDLKVLVT 83
           L++ P    +  + +V+ F    A  F+ L +D     + +GA N +++LS +++ +L  
Sbjct: 100 LSKHPTVAFEDLQPWVSNFTYPGARDFSQLALDPSGNQLIVGARNYLFRLSLANVSLLQA 159

Query: 84  HETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGS-LYQGICKLLR 142
            E    ED       R  Q+  +      N  ++L++  +  ++  CG+  +  +C   +
Sbjct: 160 TEWASSEDTR-----RSCQSKGKTEEECQNYVRVLIVAGR--KVFMCGTNAFSPMCTSRQ 212

Query: 143 LEDLFKLGE--------PYHKKEHYLSGVNESGSVFGV-IVSYSNLDDKLFIATAVDGKP 193
           + +L +  E        PY  + +  + ++  G ++   ++ +S  D  ++ +    G P
Sbjct: 213 VGNLSRTIEKINGVARCPYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRSLG-SGPP 271

Query: 194 EYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNF 253
                 +S+ L +                               P+F    V  +  G F
Sbjct: 272 LRTAQYNSKWLNE-------------------------------PNF----VAAYDIGLF 296

Query: 254 VYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA--------FNSYVEVPIGCERSG- 304
            YF   +  +    G T    VY S++ R+CK D          + ++++  + C R G 
Sbjct: 297 AYFFLRENAVEHDCGRT----VY-SRVARVCKNDVGGRFLLEDTWTTFMKARLNCSRPGE 351

Query: 305 --VEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQ 362
               Y  LQ+A+               P+ DL++ VF+      + S+  SA+C F L  
Sbjct: 352 VPFYYNELQSAFHL-------------PEQDLIYGVFTTN----VNSIAASAVCAFNLSA 394

Query: 363 INDRIKERLQSCYRGEGTLDLAWLKVKD-IP---CSSALLT-IDDNFCGL---DMNAPLG 414
           I+    +     +R +     AWL + + IP   C +   T  ++N       D      
Sbjct: 395 IS----QAFNGPFRYQENPRAAWLPIANPIPNFQCGTLPETGPNENLTERSLQDAQRLFL 450

Query: 415 VSDMVRGI---PVFTEDRDRMTSVIAYVYKN----HSLAFVGTKSGKLKKIRVDGPRG-N 466
           +S+ V+ +   P  T+D  R + ++  + +     + + ++GT+SG + K      R  +
Sbjct: 451 MSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILKALSTASRSLH 510

Query: 467 ALQYETVQVVDPG--PVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGD 524
               E + V+ PG    LR +        L++     + RVP+E C  Y+S G CLG+ D
Sbjct: 511 GCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQGACLGARD 570

Query: 525 PHCGWCVLHNTCTRKE 540
           P+CGW      C+  E
Sbjct: 571 PYCGWDGKQQRCSTLE 586


>gi|147904700 semaphorin 5A [Homo sapiens]
          Length = 1074

 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 113/540 (20%), Positives = 206/540 (38%), Gaps = 114/540 (21%)

Query: 43  FRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLS-SDLKVLVTHETGPDEDNPK-CYPPRI 100
           FR + A  F+ L  D     + +GA N +++L   DL ++   E   DE   K CY    
Sbjct: 50  FRAKNAVDFSQLTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYSK-- 107

Query: 101 VQTCNEPLTTTNNVNKMLLIDYKENRLIACGS-LYQGICKLLRLEDLFKLGE-------- 151
                +      N  ++LL+    +RL  CG+  +  +C    L +L ++ +        
Sbjct: 108 ----GKSKEECQNYIRVLLVG--GDRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARC 161

Query: 152 PYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEAD 211
           PY  + +  + +   G              +L+ ATA+D  P   P I  R L       
Sbjct: 162 PYSPQHNSTALLTAGG--------------ELYAATAMDF-PGRDPAIY-RSL------- 198

Query: 212 GMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTT 271
           G+   +   ++ +  +  P+            +V  +  GNF YF   +  +    G T 
Sbjct: 199 GILPPLRTAQYNSKWLNEPN------------FVSSYDIGNFTYFFFRENAVEHDCGKTV 246

Query: 272 KEQVYTSKLVRLCKEDTA--------FNSYVEVPIGCERSG---VEYRLLQAAYLSKAGA 320
                 S+  R+CK D          + ++++  + C R G     Y  LQ+ +      
Sbjct: 247 -----FSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFL---- 297

Query: 321 VLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGT 380
                    P+ DL++ +F+      + S+  SA+C+F L  I     +     ++ +  
Sbjct: 298 ---------PELDLIYGIFTTN----VNSIAASAVCVFNLSAI----AQAFSGPFKYQEN 340

Query: 381 LDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLG-------------VSDMVRGIPVFTE 427
              AWL   +        T+D    GL +N                 V   V  +P F E
Sbjct: 341 SRSAWLPYPNPNPHFQCGTVDQ---GLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFME 397

Query: 428 DRDRMTSVIAYVYKNHS----LAFVGTKSGKLKKIRVD-GPRGNALQYETVQVVDPG--P 480
           D  R + V   V +       + ++ T  G +KK+RV      ++   E +++       
Sbjct: 398 DNSRFSHVAVDVVQGREALVHIIYLATDYGTIKKVRVPLNQTSSSCLLEEIELFPERRRE 457

Query: 481 VLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKE 540
            +R +        L++     + ++P++ C  Y++   C+G+ DP+CGW V+   CT  E
Sbjct: 458 PIRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCTSLE 517


>gi|21361914 semaphorin B [Homo sapiens]
          Length = 761

 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 94/447 (21%), Positives = 176/447 (39%), Gaps = 81/447 (18%)

Query: 118 LLIDYKENRLIACGSL-YQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSVFGVIVSY 176
           +L+ Y    L  CG+  +   C  + L+D + L      ++  + G  +S        + 
Sbjct: 130 VLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPI---SEDKVMEGKGQSPFDPAHKHTA 186

Query: 177 SNLDDKLFIATA---VDGKPEYFPTISSRKLTKNSEADGMFAYVFHD-EFVASMIKIPSD 232
             +D  L+  T    +  +P    T+ S+ + K    D    ++ HD  FVA+   IPS 
Sbjct: 187 VLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKT---DNFLRWLHHDASFVAA---IPST 240

Query: 233 TFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA--- 289
                    +Y+ +  ++  F +F                E+++TS++ R+CK D     
Sbjct: 241 QV-------VYFFFEETASEFDFF----------------ERLHTSRVARVCKNDVGGEK 277

Query: 290 -----FNSYVEVPIGCERSG-VEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQ 343
                + ++++  + C + G + + +++ A L  A +         P    ++ VF+   
Sbjct: 278 LLQKKWTTFLKAQLLCTQPGQLPFNVIRHAVLLPADS---------PTAPHIYAVFTS-- 326

Query: 344 KRKMKSLDESALCIFILKQINDRIKERLQ---------SCYRGEGTLDLAWLKVKDIPCS 394
           + ++     SA+C F L  I    K + +         + YRG  T              
Sbjct: 327 QWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSCSVGPSSD 386

Query: 395 SALLTIDDNFCGLDMNAPLGVSDMVRGIPVFTEDRDRMTSVIAYVYK-----NHSLAFVG 449
            AL  + D+F          + + V G P+  +     T +     +     +H + ++G
Sbjct: 387 KALTFMKDHFL---------MDEQVVGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLG 437

Query: 450 TKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSKDHEQLYIMSERQLTRVPVES 509
           T +G L K  V G     L  E     DP PV R++  +     +++     + RVP  +
Sbjct: 438 TTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPV-RNLQLAPTQGAVFVGFSGGVWRVPRAN 496

Query: 510 CGQYQSCGECLGSGDPHCGWCVLHNTC 536
           C  Y+SC +C+ + DPHC W     TC
Sbjct: 497 CSVYESCVDCVLARDPHCAWDPESRTC 523


>gi|126116589 fibrocystin L [Homo sapiens]
          Length = 4243

 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 90/381 (23%), Positives = 149/381 (39%), Gaps = 54/381 (14%)

Query: 839  PAQESQW-LELSGAKSKCTN-----------PRITEIIPVTGPREGGTKVTIRGENLGLE 886
            P+Q+ Q  + ++G  +KC+            P +  I P  G  E GT +TI G      
Sbjct: 1036 PSQQPQVEVYVNGIPAKCSGDCGFTWDSNITPLVLAISPSQGSYEEGTILTIVGSGFS-- 1093

Query: 887  FRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMAR-- 944
                A  V V  V CS L    +  +++ C++        AG   + V++          
Sbjct: 1094 -PSSAVTVSVGPVGCSLLS---VDEKELKCQILNGS----AGHAPVAVSMADVGLAQNVG 1145

Query: 945  SSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPSYI 1004
              + Y+     +S + P  G ++GGT +T++G   N  S V+V  G + C       + I
Sbjct: 1146 GEEFYFVYQSQISHIWPDSGSIAGGTLLTLSGFGFNENSKVLV--GNETCNVIEGDLNRI 1203

Query: 1005 VCNTTSSDE-VLEMKVSVQVDRAKIHQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGT 1063
             C T    E  +++ V+    +A       +  ++ P I    P+   + G   + + G 
Sbjct: 1204 TCRTPKKTEGTVDISVTTNGFQATARDAFSYNCLQTPIITDFSPKVRTILGEVNLTIKGY 1263

Query: 1064 HL--DLIQNPQIRAKHGGKEHINICEVL--NATEMTCQAPALALGPDHQSDLTERPEEFG 1119
            +   +L QN  +    GGK     C++L  N T++ C  P L+ G  H   +  R   F 
Sbjct: 1264 NFGNELTQNMAVYV--GGKT----CQILHWNFTDIRCLLPKLSPGK-HDIYVEVRNWGFA 1316

Query: 1120 FILDNVQSLLILNKTNFTYYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKL 1179
               D + S +         Y   V   F   G   L  GT I ++G           +  
Sbjct: 1317 STRDKLNSSI--------QYVLEVTSMFPQRG--SLFGGTEITIRGFGF------STIPA 1360

Query: 1180 NYTVLVGEKPCTVTVSDVQLL 1200
              TVL+G  PC VT S   ++
Sbjct: 1361 ENTVLLGSIPCNVTSSSENVI 1381



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 51/213 (23%), Positives = 98/213 (46%), Gaps = 21/213 (9%)

Query: 858  PRITEIIPVTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCE 917
            P +  IIP  GP   GT++ I G N G E  +I+  V +  ++C+  +        + C 
Sbjct: 1916 PFLRGIIPSRGPP--GTEIEITGSNFGFEILEIS--VMINNIQCNVTMAN---DSVVQCI 1968

Query: 918  MGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGT 977
            +G+     HAG     +   + +  A S+ ++ +  L + ++ PS+G   GG  +T+TGT
Sbjct: 1969 VGD-----HAGGTFPVMMHHKTKGSAMSTVVFEY-PLNIQNINPSQGSFGGGQTMTVTGT 2022

Query: 978  NLNAGSNVVVMFGKQPCLFHRRSPSY--IVC-----NTTSSDEVLEMKVSVQVDRAKIHQ 1030
              N  ++++++ G + C   R    Y  ++C     N T +++  E+ V    D ++   
Sbjct: 2023 GFNPQNSIILVCGSE-CAIDRLRSDYTTLLCEIPSNNGTGAEQACEVSVVNGKDLSQSMT 2081

Query: 1031 DLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGT 1063
               +     P I  + P+    +G T + V G+
Sbjct: 2082 PFTYAVSLTPLITAVSPKRGSTAGGTRLTVVGS 2114



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 42/161 (26%), Positives = 67/161 (41%), Gaps = 7/161 (4%)

Query: 858  PRITEIIPVTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCE 917
            P IT+  P      G   +TI+G N G E     + V V G  C  L   +     I C 
Sbjct: 1240 PIITDFSPKVRTILGEVNLTIKGYNFGNELTQNMA-VYVGGKTCQILHWNFT---DIRCL 1295

Query: 918  MGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGT 977
            + +  P +H  +VE+            +S + Y + +T   + P RG + GGT++TI G 
Sbjct: 1296 LPKLSPGKHDIYVEVRNWGFASTRDKLNSSIQYVLEVT--SMFPQRGSLFGGTEITIRGF 1353

Query: 978  NLNA-GSNVVVMFGKQPCLFHRRSPSYIVCNTTSSDEVLEM 1017
              +   +   V+ G  PC     S + I C   S+  +  +
Sbjct: 1354 GFSTIPAENTVLLGSIPCNVTSSSENVIKCILHSTGNIFRI 1394



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 94/399 (23%), Positives = 151/399 (37%), Gaps = 61/399 (15%)

Query: 853  SKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAE 912
            S C +P I+ I P TG       +TI G   G      A+ V +    C   V      +
Sbjct: 1561 SSCFSPSISNITPSTGTVN--ELITIIGH--GFSNLPWANKVTIGSYPC---VVEESSED 1613

Query: 913  QIVCEMGEAKPSQHAGFVEI----------CVAVCRPEFMARSSQLYYFMTLTLSDLK-P 961
             I C + + + S   G  E            +     EF  R      F+ L   DL  P
Sbjct: 1614 SITCHI-DPQNSMDVGIRETVTLTVYNLGTAINTLSNEFDRR------FVLLPNIDLVLP 1666

Query: 962  SRGPMSGGTQVTITGTNLNAGS-NVVVMFGKQPCLFHRRSPSYIVCNTT-SSDEVLEMKV 1019
            + G  +G T VTI G+     S  V V+ G  PC     + + I C T+ ++ +++++ +
Sbjct: 1667 NAGSTTGMTSVTIKGSGFAVSSAGVKVLMGHFPCKVLSVNYTAIECETSPAAQQLVDVDL 1726

Query: 1020 SVQVDRAKIHQDLVFQYVED--PTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIRAKH 1077
             +    A+   +  F Y+E   P I  + P  + V G+  + + G  L  +      A  
Sbjct: 1727 LIHGVPAQCQGNCTFSYLESITPYITGVFP--NSVIGSVKVLIEGEGLGTVLEDI--AVF 1782

Query: 1078 GGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQSLLILNKTNFT 1137
             G +     EV N   +T     L +G  H S            +  V     L   N T
Sbjct: 1783 IGNQQFRAIEV-NENNITALVTPLPVG--HHS------------VSVVVGSKGLALGNLT 1827

Query: 1138 YYPNPVFEAFGPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKPC-TVTVSD 1196
                PV      SG   +  GT +++ G    P         N TV +G++PC  ++++ 
Sbjct: 1828 VSSPPVASLSPTSG--SIGGGTTLVITGNGFYPG--------NTTVTIGDEPCQIISINP 1877

Query: 1197 VQLLCESP-NLIGRHKVMARVGGMEYSPGM-VYIAPDSP 1233
             ++ C +P    G   V   V  + Y P +  Y   D+P
Sbjct: 1878 NEVYCRTPAGTTGMVDVKIFVNTIAYPPLLFTYALEDTP 1916



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 51/200 (25%), Positives = 80/200 (40%), Gaps = 23/200 (11%)

Query: 852  KSKCTNPRITEIIP-VTG--PRE--GGTKVTIRGENLGLEFRDIASHVKVAGVECSPLVD 906
            +  CT   +  I P +TG  P    G  KV I GE LG    DIA  +         + +
Sbjct: 1736 QGNCTFSYLESITPYITGVFPNSVIGSVKVLIEGEGLGTVLEDIAVFIGNQQFRAIEVNE 1795

Query: 907  GYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLSDLKPSRGPM 966
              I A      +G    S   G   + +       +  SS         ++ L P+ G +
Sbjct: 1796 NNITALVTPLPVGHHSVSVVVGSKGLALGN-----LTVSSP-------PVASLSPTSGSI 1843

Query: 967  SGGTQVTITGTNLNAGSNVVVMFGKQPCLFHRRSPSYIVCNT-TSSDEVLEMKVSVQVDR 1025
             GGT + ITG     G N  V  G +PC     +P+ + C T   +  ++++K+ V    
Sbjct: 1844 GGGTTLVITGNGFYPG-NTTVTIGDEPCQIISINPNEVYCRTPAGTTGMVDVKIFV---N 1899

Query: 1026 AKIHQDLVFQY-VEDPTIVR 1044
               +  L+F Y +ED   +R
Sbjct: 1900 TIAYPPLLFTYALEDTPFLR 1919



 Score = 38.5 bits (88), Expect = 0.063
 Identities = 41/157 (26%), Positives = 74/157 (47%), Gaps = 19/157 (12%)

Query: 860  ITEIIPVTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVECS--PLVDGYIPAEQIVCE 917
            I  I P  G   GG  +T+ G      F    S + V G EC+   L   Y     ++CE
Sbjct: 2001 IQNINPSQGSFGGGQTMTVTGTG----FNPQNSIILVCGSECAIDRLRSDYTT---LLCE 2053

Query: 918  MGEAKPSQHA-GFVEIC-VAVCRPEFMARSSQLY-YFMTLT--LSDLKPSRGPMSGGTQV 972
            +    PS +  G  + C V+V   + +++S   + Y ++LT  ++ + P RG  +GGT++
Sbjct: 2054 I----PSNNGTGAEQACEVSVVNGKDLSQSMTPFTYAVSLTPLITAVSPKRGSTAGGTRL 2109

Query: 973  TITGTNLNAG-SNVVVMFGKQPCLFHRRSPSYIVCNT 1008
            T+ G+  +    +V +   +  C     + ++I+C T
Sbjct: 2110 TVVGSGFSENMEDVHITIAEAKCDVEYSNKTHIICMT 2146



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 73/312 (23%), Positives = 118/312 (37%), Gaps = 86/312 (27%)

Query: 858  PRITEIIPVTGPREGGTKVTIRGE--------NLGLEFRDIASHVKV----AGVECSPLV 905
            P++TEIIP  G   G T++TIRGE        N G++  ++ + V++      + C    
Sbjct: 31   PKVTEIIPKYGSINGATRLTIRGEGFSQANQFNYGVDNAELGNSVQLISSFQSITCDVEK 90

Query: 906  DGYIPAEQIVCEMGEAKPSQHAGFVEICVA------VCRPE-------FMARSSQLYYFM 952
            D    + QI C         +   V +          C+         F A+S     F 
Sbjct: 91   DA-SHSTQITCYTRAMPEDSYTVRVSVDGVPVTENNTCKGHINSWECTFNAKS-----FR 144

Query: 953  TLTLSDLKPSRGPMSGGTQVTIT--------GTNLNAGSN------VVVMFGKQPC--LF 996
            T T+  + P  G  + GT +TI         G+N+   SN      + V  G  PC  L 
Sbjct: 145  TPTIRSITPLSG--TPGTLITIQGRIFTDVYGSNIALSSNGKNVRILRVYIGGMPCELLI 202

Query: 997  HRRSPSY-------------IVCNTTSSDEVLEMKVSVQVDR--------------AKIH 1029
             +    Y             +VC TT +  +    VS  +D               + ++
Sbjct: 203  PQSDNLYGLKLDHPNGDMGSMVCKTTGT-FIGHHNVSFILDNDYGRSFPQKMAYFVSSLN 261

Query: 1030 QDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIRAKHGGKEHINICEVL 1089
            +  +FQ   + T+  I P    + G T + + G   D    P +R   GG+     C++L
Sbjct: 262  KIAMFQTYAEVTM--IFPSQGSIRGGTTLTISGRFFDQTDFP-VRVLVGGEP----CDIL 314

Query: 1090 NATE--MTCQAP 1099
            N TE  + C+ P
Sbjct: 315  NVTENSICCKTP 326



 Score = 32.3 bits (72), Expect = 4.5
 Identities = 26/108 (24%), Positives = 51/108 (47%), Gaps = 10/108 (9%)

Query: 941  FMARSSQLYYFMTLT-LSDLKPSRGPMSGGTQVTITGTNLN-AGSNVVVMFGKQPCLFHR 998
            F++  +++  F T   ++ + PS+G + GGT +TI+G   +     V V+ G +PC    
Sbjct: 256  FVSSLNKIAMFQTYAEVTMIFPSQGSIRGGTTLTISGRFFDQTDFPVRVLVGGEPCDILN 315

Query: 999  RSPSYIVCNTTSSDEVLE--------MKVSVQVDRAKIHQDLVFQYVE 1038
             + + I C T     +L+        +K+ V  +   I  + + +Y E
Sbjct: 316  VTENSICCKTPPKPHILKTVYPGGRGLKLEVWNNSRPIRLEEILEYNE 363


>gi|157388902 semaphorin 4C [Homo sapiens]
          Length = 833

 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 35/107 (32%), Positives = 58/107 (54%), Gaps = 6/107 (5%)

Query: 430 DRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLRDMAFSK 489
           DR+T +    Y   ++ F+GT  G L K    GP  + +  E +Q+ D  P +R +  S+
Sbjct: 426 DRVTGLDGATY---TVLFIGTGDGWLLKAVSLGPWVHLI--EELQLFDQEP-MRSLVLSQ 479

Query: 490 DHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHNTC 536
             + L+  S  QL ++PV  C +Y+SC +C+ + DP+C W V  + C
Sbjct: 480 SKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRC 526


>gi|19718780 semaphorin 6B precursor [Homo sapiens]
          Length = 888

 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 140/609 (22%), Positives = 229/609 (37%), Gaps = 165/609 (27%)

Query: 11  LLSHLLMVGMGSSTLLTRQPAPLSQKQRSFVTF----------RGEPAEGFNHLVVDE-- 58
           LL  LL++G G+  L   +P PLS   R ++            R  PAEG + L +    
Sbjct: 13  LLLLLLLLG-GAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71

Query: 59  ---RTGHIYLGAVNRIYKL------SSDLKVL--VTHETGPDEDNPKCYPPRIVQTCNEP 107
              RT  +++G  + +Y++      S++L+    +T  + P + N      +    C   
Sbjct: 72  RVNRT--LFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECR-- 127

Query: 108 LTTTNNVNKMLLIDYKENRLIACGS-LYQGICKLLRLEDLFKLGE--------PYHKKEH 158
               N V  +LL D  E+ L  CGS  +  +C    ++ L  +G+        PY  K  
Sbjct: 128 ----NFVKVLLLRD--ESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPK-- 179

Query: 159 YLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVF 218
                + + ++F         D  LF AT  D     F  I           D +     
Sbjct: 180 -----HANVALFS--------DGMLFTATVTD-----FLAI-----------DAVIYRSL 210

Query: 219 HDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTS 278
            D      +K  S  F      + Y+V+    G+ VYF   +  M         E+V  S
Sbjct: 211 GDRPTLRTVKHDSKWFK-----EPYFVHAVEWGSHVYFFFREIAMEF----NYLEKVVVS 261

Query: 279 KLVRLCKEDTA---------FNSYVEVPIGCERSGVEYRLLQAAYLSKAGAVLGR-TLGV 328
           ++ R+CK D           + S+++  + C   G  +      Y +   AV G  +LG 
Sbjct: 262 RVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSH-----FYFNVLQAVTGVVSLGG 316

Query: 329 HPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKV 388
            P   ++  VFS        S+  SA+C F L Q+    + R    +R + + +  W  V
Sbjct: 317 RP---VVLAVFSTPSN----SIPGSAVCAFDLTQVAAVFEGR----FREQKSPESIWTPV 365

Query: 389 KD--IP-----CSSALLTIDDNFCGLDMNA----PLGVSDMVRGIPVFTED--------- 428
            +  +P     C +A         G+  NA    P  + + V+  P+  E          
Sbjct: 366 PEDQVPRPRPGCCAAP--------GMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPW 417

Query: 429 ------RDRMTSVIAYV----YKNHSLAFVGTKSGKLKKIRV------DGPRGNALQYET 472
                 R ++T V   V    + N ++ F+G+++G + K  V       G  G ++  E 
Sbjct: 418 ILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEE 477

Query: 473 VQVVDP-----------GPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGE-CL 520
            +   P           G  L  +        L     R + RVPV  C QY  C + C+
Sbjct: 478 FETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCI 537

Query: 521 GSGDPHCGW 529
           GS DP+CGW
Sbjct: 538 GSQDPYCGW 546


>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
          Length = 1011

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 73/340 (21%), Positives = 141/340 (41%), Gaps = 79/340 (23%)

Query: 243 YYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA---------FNSY 293
           ++++    GN+VYF   +   ++   +   + VY S++ R+CK D           + S+
Sbjct: 222 HFLHAIEYGNYVYFFFRE---IAVEHNNLGKAVY-SRVARICKNDMGGSQRVLEKHWTSF 277

Query: 294 VEVPIGCERSGVEY-------RLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRK 346
           ++  + C   G  +        +     ++    V+G           +FT        +
Sbjct: 278 LKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVG-----------VFTT-------Q 319

Query: 347 MKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKD--IP------CSSALL 398
           + S+  SA+C F +  I    K R    ++ + T D  W  V +  +P      C+   L
Sbjct: 320 LNSIPGSAVCAFSMDDIEKVFKGR----FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGL 375

Query: 399 ------TID--DNFCGLDMNAPLGVSDM--VRGIPVFTEDRDR--MTSVI----AYVYKN 442
                 +ID  D       + PL  S +  +   P FT+ R R  +T++     A  Y+N
Sbjct: 376 AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQN 435

Query: 443 HSLAFVGTKSGKLKKIRVDGPR---GNALQYETVQVVDPGPVLRD---------MAFSKD 490
           +++ FVG+++G + K+          +++  E ++  +      +         +   KD
Sbjct: 436 YTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKD 495

Query: 491 HEQLYIMSERQLTRVPVESCGQYQSCGE-CLGSGDPHCGW 529
           H  LY+     + R+P+  C +Y SC + C+ S DP+CGW
Sbjct: 496 HHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535


>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
          Length = 597

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 73/340 (21%), Positives = 141/340 (41%), Gaps = 79/340 (23%)

Query: 243 YYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA---------FNSY 293
           ++++    GN+VYF   +   ++   +   + VY S++ R+CK D           + S+
Sbjct: 222 HFLHAIEYGNYVYFFFRE---IAVEHNNLGKAVY-SRVARICKNDMGGSQRVLEKHWTSF 277

Query: 294 VEVPIGCERSGVEY-------RLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRK 346
           ++  + C   G  +        +     ++    V+G           +FT        +
Sbjct: 278 LKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVG-----------VFTT-------Q 319

Query: 347 MKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKD--IP------CSSALL 398
           + S+  SA+C F +  I    K R    ++ + T D  W  V +  +P      C+   L
Sbjct: 320 LNSIPGSAVCAFSMDDIEKVFKGR----FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGL 375

Query: 399 ------TID--DNFCGLDMNAPLGVSDM--VRGIPVFTEDRDR--MTSVI----AYVYKN 442
                 +ID  D       + PL  S +  +   P FT+ R R  +T++     A  Y+N
Sbjct: 376 AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQN 435

Query: 443 HSLAFVGTKSGKLKKIRVDGPR---GNALQYETVQVVDPGPVLRD---------MAFSKD 490
           +++ FVG+++G + K+          +++  E ++  +      +         +   KD
Sbjct: 436 YTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKD 495

Query: 491 HEQLYIMSERQLTRVPVESCGQYQSCGE-CLGSGDPHCGW 529
           H  LY+     + R+P+  C +Y SC + C+ S DP+CGW
Sbjct: 496 HHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535


>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
          Length = 1073

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 73/340 (21%), Positives = 141/340 (41%), Gaps = 79/340 (23%)

Query: 243 YYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA---------FNSY 293
           ++++    GN+VYF   +   ++   +   + VY S++ R+CK D           + S+
Sbjct: 222 HFLHAIEYGNYVYFFFRE---IAVEHNNLGKAVY-SRVARICKNDMGGSQRVLEKHWTSF 277

Query: 294 VEVPIGCERSGVEY-------RLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRK 346
           ++  + C   G  +        +     ++    V+G           +FT        +
Sbjct: 278 LKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVG-----------VFTT-------Q 319

Query: 347 MKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKD--IP------CSSALL 398
           + S+  SA+C F +  I    K R    ++ + T D  W  V +  +P      C+   L
Sbjct: 320 LNSIPGSAVCAFSMDDIEKVFKGR----FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGL 375

Query: 399 ------TID--DNFCGLDMNAPLGVSDM--VRGIPVFTEDRDR--MTSVI----AYVYKN 442
                 +ID  D       + PL  S +  +   P FT+ R R  +T++     A  Y+N
Sbjct: 376 AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQN 435

Query: 443 HSLAFVGTKSGKLKKIRVDGPR---GNALQYETVQVVDPGPVLRD---------MAFSKD 490
           +++ FVG+++G + K+          +++  E ++  +      +         +   KD
Sbjct: 436 YTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKD 495

Query: 491 HEQLYIMSERQLTRVPVESCGQYQSCGE-CLGSGDPHCGW 529
           H  LY+     + R+P+  C +Y SC + C+ S DP+CGW
Sbjct: 496 HHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535


>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
          Length = 1017

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 73/340 (21%), Positives = 141/340 (41%), Gaps = 79/340 (23%)

Query: 243 YYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA---------FNSY 293
           ++++    GN+VYF   +   ++   +   + VY S++ R+CK D           + S+
Sbjct: 222 HFLHAIEYGNYVYFFFRE---IAVEHNNLGKAVY-SRVARICKNDMGGSQRVLEKHWTSF 277

Query: 294 VEVPIGCERSGVEY-------RLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRK 346
           ++  + C   G  +        +     ++    V+G           +FT        +
Sbjct: 278 LKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVG-----------VFTT-------Q 319

Query: 347 MKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKD--IP------CSSALL 398
           + S+  SA+C F +  I    K R    ++ + T D  W  V +  +P      C+   L
Sbjct: 320 LNSIPGSAVCAFSMDDIEKVFKGR----FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGL 375

Query: 399 ------TID--DNFCGLDMNAPLGVSDM--VRGIPVFTEDRDR--MTSVI----AYVYKN 442
                 +ID  D       + PL  S +  +   P FT+ R R  +T++     A  Y+N
Sbjct: 376 AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQN 435

Query: 443 HSLAFVGTKSGKLKKIRVDGPR---GNALQYETVQVVDPGPVLRD---------MAFSKD 490
           +++ FVG+++G + K+          +++  E ++  +      +         +   KD
Sbjct: 436 YTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKD 495

Query: 491 HEQLYIMSERQLTRVPVESCGQYQSCGE-CLGSGDPHCGW 529
           H  LY+     + R+P+  C +Y SC + C+ S DP+CGW
Sbjct: 496 HHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535


>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
          Length = 998

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 73/340 (21%), Positives = 141/340 (41%), Gaps = 79/340 (23%)

Query: 243 YYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTA---------FNSY 293
           ++++    GN+VYF   +   ++   +   + VY S++ R+CK D           + S+
Sbjct: 222 HFLHAIEYGNYVYFFFRE---IAVEHNNLGKAVY-SRVARICKNDMGGSQRVLEKHWTSF 277

Query: 294 VEVPIGCERSGVEY-------RLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRK 346
           ++  + C   G  +        +     ++    V+G           +FT        +
Sbjct: 278 LKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVG-----------VFTT-------Q 319

Query: 347 MKSLDESALCIFILKQINDRIKERLQSCYRGEGTLDLAWLKVKD--IP------CSSALL 398
           + S+  SA+C F +  I    K R    ++ + T D  W  V +  +P      C+   L
Sbjct: 320 LNSIPGSAVCAFSMDDIEKVFKGR----FKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGL 375

Query: 399 ------TID--DNFCGLDMNAPLGVSDM--VRGIPVFTEDRDR--MTSVI----AYVYKN 442
                 +ID  D       + PL  S +  +   P FT+ R R  +T++     A  Y+N
Sbjct: 376 AEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQN 435

Query: 443 HSLAFVGTKSGKLKKIRVDGPR---GNALQYETVQVVDPGPVLRD---------MAFSKD 490
           +++ FVG+++G + K+          +++  E ++  +      +         +   KD
Sbjct: 436 YTVIFVGSEAGMVLKVLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKD 495

Query: 491 HEQLYIMSERQLTRVPVESCGQYQSCGE-CLGSGDPHCGW 529
           H  LY+     + R+P+  C +Y SC + C+ S DP+CGW
Sbjct: 496 HHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGW 535


>gi|188497703 semaphorin 3F [Homo sapiens]
          Length = 785

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 42/143 (29%), Positives = 66/143 (46%), Gaps = 13/143 (9%)

Query: 443 HSLAFVGTKSGKLKKIRV---DGPRGNALQYETVQVV-DPGPVLRDMAFSKDHEQLYIMS 498
           + + F+GT  G ++K+ V   D      L  E V+V  DP PV + M  S   +QLY+ S
Sbjct: 478 YEVLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVFKDPAPV-KTMTISSKRQQLYVAS 536

Query: 499 ERQLTRVPVESCGQY-QSCGECLGSGDPHCGW---CVLHNTCTRKERCERSKEPRRFASE 554
              +T + +  C  Y  +C +C  + DP+C W        T + K R  R  +  R  + 
Sbjct: 537 AVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSKRRSRR--QDVRHGNP 594

Query: 555 MKQCVRLTVHPNNISVS--QYNV 575
           ++QC     + N  +V   QY V
Sbjct: 595 IRQCRGFNSNANKNAVESVQYGV 617


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,499,265
Number of Sequences: 37866
Number of extensions: 3414241
Number of successful extensions: 7889
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 7473
Number of HSP's gapped (non-prelim): 216
length of query: 1894
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1777
effective length of database: 13,817,196
effective search space: 24553157292
effective search space used: 24553157292
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.