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Search of human proteins with 157694505
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157694505 LINE-1 type transposase domain containing 1 [Homo
sapiens]
(865 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157694505 LINE-1 type transposase domain containing 1 [Homo s... 1680 0.0
gi|239748549 PREDICTED: hypothetical protein LOC100129791 [Homo ... 165 2e-40
gi|239742533 PREDICTED: hypothetical protein LOC100129791 [Homo ... 165 2e-40
gi|239754018 PREDICTED: hypothetical protein LOC100129791 [Homo ... 164 4e-40
gi|221219020 NYD-SP11 protein [Homo sapiens] 81 5e-15
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 74 8e-13
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 72 2e-12
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 72 2e-12
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 72 2e-12
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 72 2e-12
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 71 4e-12
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 71 4e-12
gi|4506751 restin isoform a [Homo sapiens] 71 5e-12
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 70 6e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 67 9e-11
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 66 1e-10
gi|118498356 kinectin 1 isoform a [Homo sapiens] 66 2e-10
gi|118498368 kinectin 1 isoform c [Homo sapiens] 66 2e-10
gi|33620775 kinectin 1 isoform a [Homo sapiens] 66 2e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 65 2e-10
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 63 1e-09
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 63 1e-09
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 62 2e-09
gi|38044112 restin isoform b [Homo sapiens] 62 2e-09
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 62 3e-09
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 61 5e-09
gi|71061468 centromere protein E [Homo sapiens] 60 9e-09
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 60 1e-08
gi|42794779 myosin 18A isoform b [Homo sapiens] 60 1e-08
gi|28416946 myosin 18A isoform a [Homo sapiens] 60 1e-08
>gi|157694505 LINE-1 type transposase domain containing 1 [Homo
sapiens]
Length = 865
Score = 1680 bits (4351), Expect = 0.0
Identities = 865/865 (100%), Positives = 865/865 (100%)
Query: 1 MSDVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLME 60
MSDVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLME
Sbjct: 1 MSDVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLME 60
Query: 61 IQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIE 120
IQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIE
Sbjct: 61 IQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIE 120
Query: 121 GENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCN 180
GENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCN
Sbjct: 121 GENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCN 180
Query: 181 IDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEG 240
IDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEG
Sbjct: 181 IDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEG 240
Query: 241 AVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLR 300
AVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLR
Sbjct: 241 AVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLR 300
Query: 301 KFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFL 360
KFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFL
Sbjct: 301 KFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFL 360
Query: 361 KEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEE 420
KEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEE
Sbjct: 361 KEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEE 420
Query: 421 ASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEE 480
ASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEE
Sbjct: 421 ASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEE 480
Query: 481 EEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAV 540
EEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAV
Sbjct: 481 EEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAV 540
Query: 541 PTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTE 600
PTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTE
Sbjct: 541 PTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTE 600
Query: 601 ELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILE 660
ELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILE
Sbjct: 601 ELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILE 660
Query: 661 ERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDI 720
ERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDI
Sbjct: 661 ERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDI 720
Query: 721 IKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRER 780
IKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRER
Sbjct: 721 IKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRER 780
Query: 781 REITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVF 840
REITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVF
Sbjct: 781 REITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVF 840
Query: 841 LSIEEFRDYVLHMPTLRELLGNNIP 865
LSIEEFRDYVLHMPTLRELLGNNIP
Sbjct: 841 LSIEEFRDYVLHMPTLRELLGNNIP 865
>gi|239748549 PREDICTED: hypothetical protein LOC100129791 [Homo
sapiens]
Length = 338
Score = 165 bits (417), Expect = 2e-40
Identities = 94/254 (37%), Positives = 149/254 (58%), Gaps = 7/254 (2%)
Query: 611 EETEENLRSSV--INSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLED 668
E E+NL + I + + +E+ LK+ E+ L SR D LEER+ ++ED
Sbjct: 67 ENFEKNLEECITRITNTEKCLKELMELKTK---ARELREECRSLRSRCDQLEERVSAMED 123
Query: 669 QIEEFSKDTMQMTKQIISKERQ-RDIEERSRSCNIRLIGIPEK-ESYENRAEDIIKEIID 726
++ E ++ K+I E+ ++I + + N+RLIG+PE E + E+ +++II
Sbjct: 124 EMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQ 183
Query: 727 ENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRERREITYQ 786
ENF L + ++++I R+ + +R TPRHI+V+F KEK++RA+RE+ +T +
Sbjct: 184 ENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLK 243
Query: 787 GTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEF 846
G IRLTADLS +TL AR +W +F +L EK F PRI Y AK++F G+ K F+ +
Sbjct: 244 GKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQML 303
Query: 847 RDYVLHMPTLRELL 860
RD+V P L+ELL
Sbjct: 304 RDFVTTRPALQELL 317
Score = 86.3 bits (212), Expect = 1e-16
Identities = 42/102 (41%), Positives = 69/102 (67%)
Query: 216 KFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPK 275
+F K++ KE++L+A+RE+ + +G + L ADLS+ TL ++W +FNIL+E +F+P+
Sbjct: 220 RFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPR 279
Query: 276 FLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVL 317
KL+F +GEIK F D Q LR F + + +++ELLK+ L
Sbjct: 280 ISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKEAL 321
>gi|239742533 PREDICTED: hypothetical protein LOC100129791 [Homo
sapiens]
Length = 338
Score = 165 bits (417), Expect = 2e-40
Identities = 94/254 (37%), Positives = 149/254 (58%), Gaps = 7/254 (2%)
Query: 611 EETEENLRSSV--INSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLED 668
E E+NL + I + + +E+ LK+ E+ L SR D LEER+ ++ED
Sbjct: 67 ENFEKNLEECITRITNTEKCLKELMELKTK---ARELREECRSLRSRCDQLEERVSAMED 123
Query: 669 QIEEFSKDTMQMTKQIISKERQ-RDIEERSRSCNIRLIGIPEK-ESYENRAEDIIKEIID 726
++ E ++ K+I E+ ++I + + N+RLIG+PE E + E+ +++II
Sbjct: 124 EMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQ 183
Query: 727 ENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRERREITYQ 786
ENF L + ++++I R+ + +R TPRHI+V+F KEK++RA+RE+ +T +
Sbjct: 184 ENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLK 243
Query: 787 GTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEF 846
G IRLTADLS +TL AR +W +F +L EK F PRI Y AK++F G+ K F+ +
Sbjct: 244 GKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQML 303
Query: 847 RDYVLHMPTLRELL 860
RD+V P L+ELL
Sbjct: 304 RDFVTTRPALQELL 317
Score = 86.3 bits (212), Expect = 1e-16
Identities = 42/102 (41%), Positives = 69/102 (67%)
Query: 216 KFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPK 275
+F K++ KE++L+A+RE+ + +G + L ADLS+ TL ++W +FNIL+E +F+P+
Sbjct: 220 RFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPR 279
Query: 276 FLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVL 317
KL+F +GEIK F D Q LR F + + +++ELLK+ L
Sbjct: 280 ISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKEAL 321
>gi|239754018 PREDICTED: hypothetical protein LOC100129791 [Homo
sapiens]
Length = 338
Score = 164 bits (414), Expect = 4e-40
Identities = 96/265 (36%), Positives = 156/265 (58%), Gaps = 8/265 (3%)
Query: 600 EELTSKEADLTEETEENLRSSV--INSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMD 657
E++ +K ++ E E+NL + I + + +E+ LK+ E+ L SR D
Sbjct: 57 EDIQTKGKEV-ENFEKNLEECITRITNTEKCLKELMELKTK---ARELCEECRSLRSRCD 112
Query: 658 ILEERIDSLEDQIEEFSKDTMQMTKQIISKERQ-RDIEERSRSCNIRLIGIPEK-ESYEN 715
LEER+ ++ED++ E ++ K+I E+ ++I + + N+RLIG+PE E
Sbjct: 113 QLEERVSAMEDEMNEMKQEGKFREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGT 172
Query: 716 RAEDIIKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIR 775
+ E+ +++II ENF L + ++++I R+ + +R TPRHI+V+F KEK++R
Sbjct: 173 KLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLR 232
Query: 776 ASRERREITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRG 835
A+RE+ +T +G IRLTADLS +TL AR +W +F +L EK F PRI Y AK++F G
Sbjct: 233 AAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEG 292
Query: 836 KTKVFLSIEEFRDYVLHMPTLRELL 860
+ K F+ + RD+V P L+ELL
Sbjct: 293 EIKYFIDKQMLRDFVTTRPALQELL 317
Score = 86.3 bits (212), Expect = 1e-16
Identities = 42/102 (41%), Positives = 69/102 (67%)
Query: 216 KFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPK 275
+F K++ KE++L+A+RE+ + +G + L ADLS+ TL ++W +FNIL+E +F+P+
Sbjct: 220 RFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPR 279
Query: 276 FLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVL 317
KL+F +GEIK F D Q LR F + + +++ELLK+ L
Sbjct: 280 ISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKEAL 321
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 80.9 bits (198), Expect = 5e-15
Identities = 135/580 (23%), Positives = 248/580 (42%), Gaps = 68/580 (11%)
Query: 14 RLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETL 73
+LA++KEN+ Y K E+LT + K + V K+ + NK +L ++++ + +E +
Sbjct: 1852 KLAQRKENLLYNK-ERLTHSKKQLVQV-----KNKLGMFNK--ILAQVEEKLTQEKETVI 1903
Query: 74 KNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGK--IEGENSKIGDDNE 131
K K K + +V++S Q+ + LAL+K + GK + GE ++
Sbjct: 1904 KKKEKLAETEKKLV-QVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKA 1962
Query: 132 -NLTFKLEVNE----LSGK--LDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDR 184
NL K E + GK L ++ +K+ Q E +E S+EE + +DR
Sbjct: 1963 LNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDR 2022
Query: 185 DGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLT 244
L E E K G+ EF + R + Q+ K + E + + +
Sbjct: 2023 I------LAMEESEIAK-GKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNK 2075
Query: 245 LVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAF---KCDGEIKTFSDLQSL-- 299
++ L T D K + + F+ E +L+ K D + FS+ +S
Sbjct: 2076 ILKALQKLTRDERKLTQEEIKMTKMK--RALFVKERRLSIEQSKLDIKEWDFSEKRSELT 2133
Query: 300 ---RKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLS 356
+K A ++ + ++ ++ ++E++ + K + K + ++D + G + +
Sbjct: 2134 KDEKKLARKQRKLANKMRRMINKEEKMTEEESK--LARKHSEVILDDEEEGGIEEEEVIP 2191
Query: 357 FLFL-----KEVKVA-KPEEMKNLETQE----EEFSE-----LEELD----------EEA 391
FL KE K KP+E + + E E FSE L+EL+ EE
Sbjct: 2192 FLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEER 2251
Query: 392 SGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTL 451
E+ E+ EEEEE E EE++ EE + E+++E+ E++ F+
Sbjct: 2252 EEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEE 2311
Query: 452 VDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPF 511
+ ++ E E SD E S+E+ E+E K + K++ +++ S R +E
Sbjct: 2312 IMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQ----EQRRKSLRGRERVL 2367
Query: 512 SYLVG-DSGKKKLVKHQVVHKTQEE-EETAVPTSQGTGTP 549
S L G GK + ++ V+ ++ TA+ + T P
Sbjct: 2368 SILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVP 2407
Score = 63.2 bits (152), Expect = 1e-09
Identities = 134/644 (20%), Positives = 261/644 (40%), Gaps = 103/644 (15%)
Query: 164 ESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNK 223
+S+ + E TL R+G + TE + E ++ + R+ + +K + +
Sbjct: 1532 KSKEQQYKDEEEVTLEEEVSREGEEKEQ-QVTEEQRHIQEEHKWARIHRKRARAEKKRAQ 1590
Query: 224 EEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLA 283
EE A EEK+ +E + L+ A + I++
Sbjct: 1591 EERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQD------------------------ 1626
Query: 284 FKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDS 343
D E+ Q+ KFA ++ ++ + + + + E++ Q +K + +K +K +
Sbjct: 1627 ---DREM-----AQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKK--LAKKWEKVAREE 1676
Query: 344 KHRAGEITSDGLSFLFLKEVKVAKPEEM----KNLETQEEEFSELEELDEEASGMEDDED 399
+ ++ G +K + K EE+ +NL+ QE+E + +EL+E
Sbjct: 1677 E----KLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELA--QELEE---------- 1720
Query: 400 TSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVE 459
LE + EE S EEE +E L E++ EEEE +++ + T + + E+
Sbjct: 1721 ---LEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELL 1777
Query: 460 ITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSG 519
I + E EEE G+ E L EKK QK + + +
Sbjct: 1778 IQE---KEKLAQHKEKMPEEEERLGRKRE-------QLIEKKMKLAQKRERWINSMEELT 1827
Query: 520 KKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDE--HKKHSHTNL 577
K K++ +Q + QE++ A + LA ++L + + H K +
Sbjct: 1828 KNKMILYQKKNLAQEKKNLAQEKEK----------LAQRKENLLYNKERLTHSKKQLVQV 1877
Query: 578 SISTGVTK--LKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNL 635
G+ L + EEK +E K+ + ETE+ L V +S+ + +E++
Sbjct: 1878 KNKLGMFNKILAQVEEK---LTQEKETVIKKKEKLAETEKKL-VQVEDSLAKKQEKLAQE 1933
Query: 636 KSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMT--KQIISK------ 687
K + + L +DI +E +L +++ +++ M++ K+ +SK
Sbjct: 1934 KMKLALEKAMVQGKKRLRGELDIAKEE-KALNLEMKRLAEEKMRLVEGKETLSKGETPET 1992
Query: 688 ERQRDIEERSRSCNIRLIGIPEK-ESYENRAEDIIKEIIDENFAELKKGSSLEIVSACRV 746
RQR + + + R + + EK +E+R + + I + E +G + V R
Sbjct: 1993 SRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRI-FVQGQRK 2051
Query: 747 PSKIDEKRLTPRHILVKFWNSSDKEKIIRA----SRERREITYQ 786
+K K + R L K + KI++A +R+ R++T +
Sbjct: 2052 LAKASRKLIKKRESLSK--EPAKLNKILKALQKLTRDERKLTQE 2093
Score = 49.3 bits (116), Expect = 2e-05
Identities = 125/633 (19%), Positives = 250/633 (39%), Gaps = 135/633 (21%)
Query: 186 GNRNVHLEFTERESRKDGED---EFVKEMREERKFQKLKNK---------EEVLK-ASRE 232
GN + E +++E +K + + K +++ERK K+K + EEV + A+ E
Sbjct: 1379 GNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLE 1438
Query: 233 EKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKT 292
EKV+ EG ++ + + + + D K W + GE +
Sbjct: 1439 EKVVKQEGKLVMI--ERTPSWQDWKKAWDEWKQV--------------------HGETR- 1475
Query: 293 FSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITS 352
S K+ +E K +L ++E+++Q G K +E+
Sbjct: 1476 ----------KSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEE----------------- 1508
Query: 353 DGLSFLFLKEVKVAKPEEMKNL-------ETQEEEFSELEE--LDEEASGMEDDEDTSGL 403
L+E K K EE K + +++E+++ + EE L+EE S ++++
Sbjct: 1509 ------MLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVT 1562
Query: 404 EE----EEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVE 459
EE +EE + A E L +EEE+ ++++ A+ V+
Sbjct: 1563 EEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVK 1622
Query: 460 ITSDGMETT-----FIDSVEDSESEEEEEGKSSETGKVKTTSLTEK--KASRRQKEIPFS 512
IT D E F E E+ + +E K L +K K +R +++
Sbjct: 1623 ITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEK---- 1678
Query: 513 YLVGDSGKKKLVKHQVVHKTQE--EEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHK 570
L GK VK+ + K +E + E + + LA + LE +E
Sbjct: 1679 -LAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKE--------LAQELEELEWDMEELS 1729
Query: 571 -KHSHTNLSISTGVTKLKK-TEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREI 628
K N V + KK EE++ E+L+ +E L +E E ++
Sbjct: 1730 WKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQE--------- 1780
Query: 629 KEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKE 688
KE++ K ++ + L + + L E+ L + E + ++TK +
Sbjct: 1781 KEKLAQHKE------KMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILY 1834
Query: 689 RQRDIEERSRSCNIRLIGIPEKESYENRAEDII--KEIIDENFAELKKGSSLEIVSACRV 746
+++++ + ++ EKE R E+++ KE + + +L + + ++ ++
Sbjct: 1835 QKKNLAQEKKNL------AQEKEKLAQRKENLLYNKERLTHSKKQLVQVKN-KLGMFNKI 1887
Query: 747 PSKIDEKRLTPRHILVKFWNSSDKEKIIRASRE 779
++++EK + ++K KEK+ ++
Sbjct: 1888 LAQVEEKLTQEKETVIK-----KKEKLAETEKK 1915
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 73.6 bits (179), Expect = 8e-13
Identities = 137/732 (18%), Positives = 303/732 (41%), Gaps = 92/732 (12%)
Query: 3 DVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLD---LKCKDVSAIMNKF---K 56
+V +V A++ ++K N+ + + E++ E +K+I + + ++C+++ +++ + K
Sbjct: 781 NVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEK 840
Query: 57 VLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMV 116
VL+ + + +E L++DL E+KN+ N +R E Q ++ + +
Sbjct: 841 VLLRKELEEIQSEKEALQSDLL----------EMKNA-NEKTRLENQNLLIQVEEVSQTC 889
Query: 117 GKIEGENSK---IGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGS 173
K E N K ++ENL LE EL + + K P ++ +
Sbjct: 890 SKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKS-PSVKNDPLSSVKE 948
Query: 174 MEETLCNIDDRDGNRN-----VHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLK 228
+EE + N++ + + L + + D + + ++EE + L+++++ L
Sbjct: 949 LEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEE--LESLRSEKDQLS 1006
Query: 229 ASREEKVLMDEGAV-LTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCD 287
AS + + E L L + S LD+ K+ R N+FE +
Sbjct: 1007 ASMRDLIQGAESYKNLLLEYEKQSEQLDVEKE--------RANNFEHRI----------- 1047
Query: 288 GEIKTFSDL-QSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQ---EKRDKTLIDS 343
DL + LR Q ++ +D+L + E + + +Q +R K ++D
Sbjct: 1048 ------EDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDK 1101
Query: 344 KHRAGEITSD------GLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDD 397
+ A ++ + + L+E++V +E K L+ +E +++ ++ + M +
Sbjct: 1102 ELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNME 1161
Query: 398 ---------EDTSGLEEEEEEPSGLEEEEEEEASGLE--EDEASGLEEEEEQTSEQDSTF 446
E L + + LE+E + + E ++E + L+ +Q E+++
Sbjct: 1162 IADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKI 1221
Query: 447 QGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQ 506
+ LV K E+ S ET + + E E + E K++ +T +K +
Sbjct: 1222 K-QLLVKTKKELA-DSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEK-HKIH 1278
Query: 507 KEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCL--------TLCLASP 558
+ + S + ++ L +Q +EE A Q T T +
Sbjct: 1279 EHLKTS---AEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQK 1335
Query: 559 SKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTS--KEADLTEETEEN 616
+KS+ + E K +L + K+K + + + ++ EL + E D E
Sbjct: 1336 NKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNK 1395
Query: 617 LRSSVINSIREIKEEIGNLKSSHSGV-LEIENSVDDLSSRMDILEERIDSLEDQIEEFSK 675
+ ++ E++E++ +++S + + E +V L+S+ ++L ++E +
Sbjct: 1396 MLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHR 1455
Query: 676 DTMQMTKQIISK 687
T++ +Q +SK
Sbjct: 1456 KTVETLQQQLSK 1467
Score = 70.9 bits (172), Expect = 5e-12
Identities = 141/743 (18%), Positives = 295/743 (39%), Gaps = 120/743 (16%)
Query: 44 KCKDVSAIMNKFKVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQ 103
+ DV + K + +D + E + L+ + + +L + +PE++N+ +
Sbjct: 512 QASDVHELQQKLRTAFTEKDALLETVNR-LQGENEKLLSQQELVPELENTIKNLQEKNGV 570
Query: 104 QIINLALQKTGMVGKIEGENSKIGDDNENLTFKLE-------------------VNELSG 144
+++L+ Q+ M+ ++EG+ + + ++ ++ KL+ + EL
Sbjct: 571 YLLSLS-QRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGK 629
Query: 145 KLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGN-RNVHLEFTERESRKDG 203
K++ T +YNS + E + E+ G +EETL D D + ++ K+
Sbjct: 630 KVEQTIQYNS-------ELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEV 682
Query: 204 EDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNV 263
VK + EE KL ++++ L E + E +L L + + +
Sbjct: 683 LSAEVKSLYEENN--KLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDN 740
Query: 264 FNILRENDFEPK---------FLCEVKLAFKCDGEIKTFSDL-----QSLRKFASQKSS- 308
N L EN+ K FL E+ D E K ++ +SL K +K +
Sbjct: 741 LNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNL 800
Query: 309 --------------VKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDG 354
+K L ++ + Q EE+ R Y +++K L+ + + +
Sbjct: 801 AFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDY----EQEKVLLRKELEEIQSEKEA 856
Query: 355 LS--FLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSG 412
L L +K E +NL Q EE S+ E + ++++ ++E E
Sbjct: 857 LQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSE----IHNEKEKCFIKEHENLKPL 912
Query: 413 LEEEEEEE--------------ASGLEEDEASGLEEEEE-------QTSEQDSTFQGHTL 451
LE++E + + ++ D S ++E EE + E++ L
Sbjct: 913 LEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKL 972
Query: 452 VDAKHEVEITSDGMET-TFIDSVEDSESEEEEEGKSSE-----TGKVKTTSLTEKKASR- 504
V K + E+ S ET T + +E SE+++ S K L +K S
Sbjct: 973 VAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQ 1032
Query: 505 ----RQKEIPFSYLVGDSGKK---KLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCL-- 555
+++ F + + D ++ ++ + ++ E+ + T Q L
Sbjct: 1033 LDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEV 1092
Query: 556 ----ASPSKSLE----MSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEA 607
A K LE + K+H+ T + +L+K +++ +T+ EL K+A
Sbjct: 1093 QRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDA 1152
Query: 608 DLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLE 667
T + + + R +KE L + ++ + ++E + + + L+E I SL+
Sbjct: 1153 QQTTL----MNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQ 1208
Query: 668 DQIEEFSKDTMQMTKQIISKERQ 690
++++ + ++ KQ++ K ++
Sbjct: 1209 SSVQQYEEKNTKI-KQLLVKTKK 1230
Score = 56.2 bits (134), Expect = 1e-07
Identities = 160/784 (20%), Positives = 316/784 (40%), Gaps = 113/784 (14%)
Query: 2 SDVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVS-AIMNKFKVLME 60
S + T + + AKK+ + + + TE +K+I +L+ K V+ + K L E
Sbjct: 20 SKLETLPKEDLIKFAKKQMMLIQKAKSRCTELEKEIE---ELRSKPVTEGTGDIIKALTE 76
Query: 61 IQDLMFEEMRETLKNDLKAVLGGKATIPEVKNS--ENSSSRTEFQQI-INLALQKTGMVG 117
D + E ET + L EV++S + + E +Q IN + +
Sbjct: 77 RLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKN 136
Query: 118 KIEGENSKIGDDNENLTFKLEVN-----ELSGKLDNTNEYNSNDGKKLPQGESRSYEVMG 172
++ SK +D NL +LE ELS +L N NS D K Q E ++
Sbjct: 137 ELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQN--NSEDNVKKLQEEIE--KIRP 192
Query: 173 SMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMRE-----ERKFQKLKN--KEE 225
EE + + + ++ D + E V +++ + +QK N +EE
Sbjct: 193 GFEEQILYLQK------------QLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEE 240
Query: 226 VL--KASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILR-----ENDFEPKFLC 278
+L KA +E+V + + + A +I+K N+++ E + + K+ C
Sbjct: 241 LLQLKAIHQEEV---KELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYEC 297
Query: 279 EVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDK 338
E++ K + + S+ + + V++++ + + E+ + K +
Sbjct: 298 ELENLRKATSNANQDNQICSI--LLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEV 355
Query: 339 TLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDE 398
T +++ E+ + + F E + + + + L +EE+ +E+L E +G+ + +
Sbjct: 356 TYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGL-NKQ 414
Query: 399 DTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQT--SEQDSTFQGHTLVDAKH 456
+E+ E L+E+ ++E S L E S E+E+ Q Q L K
Sbjct: 415 FCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQ 474
Query: 457 EVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVG 516
E + + + E E + E G+S+ + S+ +++AS E+
Sbjct: 475 EAILNYESLR-------EIMEILQTELGESAGKISQEFESMKQQQASDVH-ELQQKLRTA 526
Query: 517 DSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTN 576
+ K L+ + V++ Q E E + + L L + K+L+ +K+
Sbjct: 527 FTEKDALL--ETVNRLQGENEKLLSQQE------LVPELENTIKNLQ------EKNGVYL 572
Query: 577 LSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNL- 635
LS+S T LK EL K LTEE ++ IN ++ EE+ N
Sbjct: 573 LSLSQRDTMLK-------------ELEGKINSLTEEKDD-----FINKLKNSHEEMDNFH 614
Query: 636 ---KSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKD---------------- 676
+ +LE+ V+ LE++++ L +EE K+
Sbjct: 615 KKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMK 674
Query: 677 TMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDENFAELKKGS 736
+ K+++S E + EE ++ + + + E + ++ ED+ I+ E+ +L+K
Sbjct: 675 VLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDV---ILKEHITQLEKKL 731
Query: 737 SLEI 740
L +
Sbjct: 732 QLMV 735
Score = 34.3 bits (77), Expect = 0.51
Identities = 30/167 (17%), Positives = 76/167 (45%), Gaps = 4/167 (2%)
Query: 591 EKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVD 650
EK+ L ++ +T D+ + E L + ++ ++ + K + E+E+SV
Sbjct: 52 EKEIEELRSKPVTEGTGDIIKALTERLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVT 111
Query: 651 DLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEK 710
+ LE+ + +IE + M + + E + +++++ + + E+
Sbjct: 112 KMGDAHKELEQSHINYVKEIENLKNELMAVRSKY--SEDKANLQKQLEEAMNTQLELSEQ 169
Query: 711 ESYENRAEDIIKEIIDENFAELKKGSSLEIVSACR-VPSKIDEKRLT 756
++N +ED +K+ + E +++ G +I+ + + + DEK+ T
Sbjct: 170 LKFQNNSEDNVKK-LQEEIEKIRPGFEEQILYLQKQLDATTDEKKET 215
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 72.0 bits (175), Expect = 2e-12
Identities = 147/737 (19%), Positives = 283/737 (38%), Gaps = 98/737 (13%)
Query: 5 STSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAI---------MNKF 55
ST+ Q + AK+++ +T +K+ ET A V +++ K A+ +
Sbjct: 1161 STATQQELR--AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA 1218
Query: 56 KVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKN-------------SENSSSRTEF 102
K ++ E+ L +L+ + K + K S+ +R E
Sbjct: 1219 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1278
Query: 103 QQII----NLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGK 158
+ N TGM+ + EG+ K+ D +L+ +L+ + L N
Sbjct: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ--DTQELLQEETRQKLNVST 1336
Query: 159 KLPQGESRSYEVMGSMEETL---CNIDDRDGNRNVHLEFTERESRKDGED-EFVKEMREE 214
KL Q E + ++E + N++ N+ L +S+K +D E EE
Sbjct: 1337 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS----DSKKKLQDFASTVEALEE 1392
Query: 215 RKFQKLKNKEEVLKASREEKVLMD--EGAVLTLVADLSSATLDISKQWSNVFNILRENDF 272
K + K E + + E+ D E L +L +D+ Q V N+ ++
Sbjct: 1393 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1452
Query: 273 EPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGI 332
+ L E K + + ++ ++ K ++ S+ L++ L KEE+ + + +
Sbjct: 1453 FDQLLAEEKNISSKYADERDRAEAEAREK-ETKALSLARALEEALEAKEELERTNK---M 1508
Query: 333 QEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEAS 392
+ + L+ SK G+ + L++ K A +M+ ++TQ LEEL++E
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHE------LEKSKRALETQMEEMKTQ------LEELEDELQ 1556
Query: 393 GMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEE--EEQTSEQDSTFQGHT 450
ED + LE + G E + + E++ L+ + E +T +D Q
Sbjct: 1557 ATEDAK--LRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1614
Query: 451 LVDAKHEVEITSDGMETTFIDSVEDSES----------------EEEEEGKSSETGKVKT 494
AK ++E +E +++ E E E+ ++S T
Sbjct: 1615 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFAT 1674
Query: 495 TSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQV-VHKTQEEEETAVPTSQGTGTPCLTL 553
EKKA + E L D + + Q + K + EE A S
Sbjct: 1675 AKENEKKA--KSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR 1732
Query: 554 CLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEET 613
L + LE +E + + ++S V K + E+ L TE T+++ + +
Sbjct: 1733 RLEARIAQLEEELEEEQGNME---AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1789
Query: 614 EENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEF 673
E + + + E++ G +KS S + LE +I LE+Q+E+
Sbjct: 1790 LERQNKELRSKLHEME---GAVKSK-------------FKSTIAALEAKIAQLEEQVEQE 1833
Query: 674 SKDTMQMTKQIISKERQ 690
+++ TK + K+++
Sbjct: 1834 AREKQAATKSLKQKDKK 1850
Score = 60.1 bits (144), Expect = 9e-09
Identities = 147/825 (17%), Positives = 332/825 (40%), Gaps = 141/825 (17%)
Query: 16 AKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEI------QDLMFEEM 69
AK+++ +T MK Q ++ A L L+ + K K L+++ +E+
Sbjct: 807 AKRQQQLTAMKVIQ-----RNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDEL 861
Query: 70 RETLKNDLKAVLGGKATIPEVKNSENSSSR-TEFQQIINLALQ-KTGMVGKIEGENSKIG 127
++T + KA E+K E S+ TE + ++ LQ +T + + E ++
Sbjct: 862 QKTKERQQKAE-------NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLA 914
Query: 128 DDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGN 187
K E+ E+ +++ E + G++L + + M +EE L ++
Sbjct: 915 AK------KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAAR 966
Query: 188 RNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVA 247
+ + LE E++ +K++ +E +N K S+E K+L +
Sbjct: 967 QKLQLEKVTAEAK-------IKKLEDEILVMDDQNN----KLSKERKLLEER-------- 1007
Query: 248 DLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSL-RKFASQK 306
+S T +++++ N+ + + + E+++ K E K+ +L+ L RK
Sbjct: 1008 -ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK--KEEKSRQELEKLKRKLEGDA 1064
Query: 307 SSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVA 366
S E + D+ Q E+ K + +K ++ EI + ++E++
Sbjct: 1065 SDFHEQIADLQAQIAEL-----KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH 1119
Query: 367 KPEEMKNLETQ-------EEEFSEL-EELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEE 418
+ ++L+++ E++ +L EEL+ + +ED D++ ++E L + E
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE------LRAKRE 1173
Query: 419 EEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSES 478
+E + L++ +E+T ++ Q A+ E+T + + D
Sbjct: 1174 QEVTVLKK-------ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK 1226
Query: 479 EEEEEGKSSETGKVKTTSLTEKKASRRQKEIP-----FSYLVGDSGKKKLVKHQVVHKTQ 533
+ E+ + G+++ +++ ++K++ D + + + VHK Q
Sbjct: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
Query: 534 EEEETAVPTSQGTGTPCLTLC--LASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEE 591
E E+ + L +AS S L+ + + ++ + L++ST KL++ EE
Sbjct: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST---KLRQLEE 1343
Query: 592 KKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDD 651
+++ L ++ +E + E K+ + H L I+ S D
Sbjct: 1344 ERN-------------SLQDQLDEEM---------EAKQNL----ERHISTLNIQLS--D 1375
Query: 652 LSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKE 711
++ +++LE+ + F K+ +T+Q K D E+++
Sbjct: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK------------- 1422
Query: 712 SYENRAEDIIKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKE 771
NR + + +++ + + + S+LE + K D+ ++I K+ + D
Sbjct: 1423 ---NRLQQELDDLVVDLDNQRQLVSNLE-----KKQRKFDQLLAEEKNISSKYADERD-- 1472
Query: 772 KIIRASRERREITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLE 816
RA E RE + + + +L+ + + + + K +E
Sbjct: 1473 ---RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514
Score = 55.1 bits (131), Expect = 3e-07
Identities = 132/665 (19%), Positives = 262/665 (39%), Gaps = 83/665 (12%)
Query: 68 EMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKT--GMVGKIEGENSK 125
E E LK +L+ L AT E++ + R + ++ AL + +++ K
Sbjct: 1146 EELEALKTELEDTLDSTATQQELR-----AKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
Query: 126 IGDDNENLTFKLE-VNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDR 184
E LT +LE LD + + L GE R V+G ++ +
Sbjct: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA-GELR---VLGQAKQEV-----E 1251
Query: 185 DGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREE------KVLMD 238
+ + + E +S+ + E+ + K KL+N+ E + E K+ D
Sbjct: 1252 HKKKKLEAQVQELQSKCSDGERARAELND--KVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 239 EGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQS 298
++ + + D + ++Q NV LR+ + E L + + D E++ +L+
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD-----QLDEEMEAKQNLER 1364
Query: 299 -LRKFASQKSSVKELLKDVLPQKEEINQGGRKYG------IQEKRDKT-----LIDSKHR 346
+ Q S K+ L+D E + +G +++ Q+ +K L +K+R
Sbjct: 1365 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424
Query: 347 AGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEE---ASGMEDDEDTSGL 403
+ D + L + V+ NLE ++ +F +L L EE +S D+ D +
Sbjct: 1425 LQQELDDLVVDLDNQRQLVS------NLEKKQRKFDQL--LAEEKNISSKYADERDRAEA 1476
Query: 404 EEEEEEPSGLE-----EEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEV 458
E E+E L EE E LE E E+ S +D + HE+
Sbjct: 1477 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN------VHEL 1530
Query: 459 EITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDS 518
E + +ET ++ ++ E E+E +++E K++ + + ++++ +
Sbjct: 1531 EKSKRALETQ-MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 519 GKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLS 578
+++L + ++T+ E+E Q L K LE+ D K +
Sbjct: 1590 KRRQLQRQLHEYETELEDER----KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 579 ISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSS 638
+ KL+ + R L + E T + E S+ + +++E++ + +
Sbjct: 1646 ---QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702
Query: 639 HSGV-LEIENSVDDLSSRMD----------ILEERIDSLEDQIEEFSKDTMQMTKQIISK 687
LE E ++L+S + LE RI LE+++EE + M+ ++
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 688 ERQRD 692
+Q +
Sbjct: 1763 TQQAE 1767
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 72.0 bits (175), Expect = 2e-12
Identities = 147/737 (19%), Positives = 283/737 (38%), Gaps = 98/737 (13%)
Query: 5 STSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAI---------MNKF 55
ST+ Q + AK+++ +T +K+ ET A V +++ K A+ +
Sbjct: 1168 STATQQELR--AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA 1225
Query: 56 KVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKN-------------SENSSSRTEF 102
K ++ E+ L +L+ + K + K S+ +R E
Sbjct: 1226 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1285
Query: 103 QQII----NLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGK 158
+ N TGM+ + EG+ K+ D +L+ +L+ + L N
Sbjct: 1286 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ--DTQELLQEETRQKLNVST 1343
Query: 159 KLPQGESRSYEVMGSMEETL---CNIDDRDGNRNVHLEFTERESRKDGED-EFVKEMREE 214
KL Q E + ++E + N++ N+ L +S+K +D E EE
Sbjct: 1344 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS----DSKKKLQDFASTVEALEE 1399
Query: 215 RKFQKLKNKEEVLKASREEKVLMD--EGAVLTLVADLSSATLDISKQWSNVFNILRENDF 272
K + K E + + E+ D E L +L +D+ Q V N+ ++
Sbjct: 1400 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1459
Query: 273 EPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGI 332
+ L E K + + ++ ++ K ++ S+ L++ L KEE+ + + +
Sbjct: 1460 FDQLLAEEKNISSKYADERDRAEAEAREK-ETKALSLARALEEALEAKEELERTNK---M 1515
Query: 333 QEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEAS 392
+ + L+ SK G+ + L++ K A +M+ ++TQ LEEL++E
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHE------LEKSKRALETQMEEMKTQ------LEELEDELQ 1563
Query: 393 GMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEE--EEQTSEQDSTFQGHT 450
ED + LE + G E + + E++ L+ + E +T +D Q
Sbjct: 1564 ATEDAK--LRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1621
Query: 451 LVDAKHEVEITSDGMETTFIDSVEDSES----------------EEEEEGKSSETGKVKT 494
AK ++E +E +++ E E E+ ++S T
Sbjct: 1622 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFAT 1681
Query: 495 TSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQV-VHKTQEEEETAVPTSQGTGTPCLTL 553
EKKA + E L D + + Q + K + EE A S
Sbjct: 1682 AKENEKKA--KSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR 1739
Query: 554 CLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEET 613
L + LE +E + + ++S V K + E+ L TE T+++ + +
Sbjct: 1740 RLEARIAQLEEELEEEQGNME---AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1796
Query: 614 EENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEF 673
E + + + E++ G +KS S + LE +I LE+Q+E+
Sbjct: 1797 LERQNKELRSKLHEME---GAVKSK-------------FKSTIAALEAKIAQLEEQVEQE 1840
Query: 674 SKDTMQMTKQIISKERQ 690
+++ TK + K+++
Sbjct: 1841 AREKQAATKSLKQKDKK 1857
Score = 60.1 bits (144), Expect = 9e-09
Identities = 147/825 (17%), Positives = 332/825 (40%), Gaps = 141/825 (17%)
Query: 16 AKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEI------QDLMFEEM 69
AK+++ +T MK Q ++ A L L+ + K K L+++ +E+
Sbjct: 814 AKRQQQLTAMKVIQ-----RNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDEL 868
Query: 70 RETLKNDLKAVLGGKATIPEVKNSENSSSR-TEFQQIINLALQ-KTGMVGKIEGENSKIG 127
++T + KA E+K E S+ TE + ++ LQ +T + + E ++
Sbjct: 869 QKTKERQQKAE-------NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLA 921
Query: 128 DDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGN 187
K E+ E+ +++ E + G++L + + M +EE L ++
Sbjct: 922 AK------KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAAR 973
Query: 188 RNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVA 247
+ + LE E++ +K++ +E +N K S+E K+L +
Sbjct: 974 QKLQLEKVTAEAK-------IKKLEDEILVMDDQNN----KLSKERKLLEER-------- 1014
Query: 248 DLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSL-RKFASQK 306
+S T +++++ N+ + + + E+++ K E K+ +L+ L RK
Sbjct: 1015 -ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK--KEEKSRQELEKLKRKLEGDA 1071
Query: 307 SSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVA 366
S E + D+ Q E+ K + +K ++ EI + ++E++
Sbjct: 1072 SDFHEQIADLQAQIAEL-----KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH 1126
Query: 367 KPEEMKNLETQ-------EEEFSEL-EELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEE 418
+ ++L+++ E++ +L EEL+ + +ED D++ ++E L + E
Sbjct: 1127 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE------LRAKRE 1180
Query: 419 EEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSES 478
+E + L++ +E+T ++ Q A+ E+T + + D
Sbjct: 1181 QEVTVLKK-------ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK 1233
Query: 479 EEEEEGKSSETGKVKTTSLTEKKASRRQKEIP-----FSYLVGDSGKKKLVKHQVVHKTQ 533
+ E+ + G+++ +++ ++K++ D + + + VHK Q
Sbjct: 1234 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1293
Query: 534 EEEETAVPTSQGTGTPCLTLC--LASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEE 591
E E+ + L +AS S L+ + + ++ + L++ST KL++ EE
Sbjct: 1294 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST---KLRQLEE 1350
Query: 592 KKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDD 651
+++ L ++ +E + E K+ + H L I+ S D
Sbjct: 1351 ERN-------------SLQDQLDEEM---------EAKQNL----ERHISTLNIQLS--D 1382
Query: 652 LSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKE 711
++ +++LE+ + F K+ +T+Q K D E+++
Sbjct: 1383 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK------------- 1429
Query: 712 SYENRAEDIIKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKE 771
NR + + +++ + + + S+LE + K D+ ++I K+ + D
Sbjct: 1430 ---NRLQQELDDLVVDLDNQRQLVSNLE-----KKQRKFDQLLAEEKNISSKYADERD-- 1479
Query: 772 KIIRASRERREITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLE 816
RA E RE + + + +L+ + + + + K +E
Sbjct: 1480 ---RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521
Score = 55.1 bits (131), Expect = 3e-07
Identities = 132/665 (19%), Positives = 262/665 (39%), Gaps = 83/665 (12%)
Query: 68 EMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKT--GMVGKIEGENSK 125
E E LK +L+ L AT E++ + R + ++ AL + +++ K
Sbjct: 1153 EELEALKTELEDTLDSTATQQELR-----AKREQEVTVLKKALDEETRSHEAQVQEMRQK 1207
Query: 126 IGDDNENLTFKLE-VNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDR 184
E LT +LE LD + + L GE R V+G ++ +
Sbjct: 1208 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA-GELR---VLGQAKQEV-----E 1258
Query: 185 DGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREE------KVLMD 238
+ + + E +S+ + E+ + K KL+N+ E + E K+ D
Sbjct: 1259 HKKKKLEAQVQELQSKCSDGERARAELND--KVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 239 EGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQS 298
++ + + D + ++Q NV LR+ + E L + + D E++ +L+
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD-----QLDEEMEAKQNLER 1371
Query: 299 -LRKFASQKSSVKELLKDVLPQKEEINQGGRKYG------IQEKRDKT-----LIDSKHR 346
+ Q S K+ L+D E + +G +++ Q+ +K L +K+R
Sbjct: 1372 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431
Query: 347 AGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEE---ASGMEDDEDTSGL 403
+ D + L + V+ NLE ++ +F +L L EE +S D+ D +
Sbjct: 1432 LQQELDDLVVDLDNQRQLVS------NLEKKQRKFDQL--LAEEKNISSKYADERDRAEA 1483
Query: 404 EEEEEEPSGLE-----EEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEV 458
E E+E L EE E LE E E+ S +D + HE+
Sbjct: 1484 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN------VHEL 1537
Query: 459 EITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDS 518
E + +ET ++ ++ E E+E +++E K++ + + ++++ +
Sbjct: 1538 EKSKRALETQ-MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 519 GKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLS 578
+++L + ++T+ E+E Q L K LE+ D K +
Sbjct: 1597 KRRQLQRQLHEYETELEDER----KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 579 ISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSS 638
+ KL+ + R L + E T + E S+ + +++E++ + +
Sbjct: 1653 ---QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1709
Query: 639 HSGV-LEIENSVDDLSSRMD----------ILEERIDSLEDQIEEFSKDTMQMTKQIISK 687
LE E ++L+S + LE RI LE+++EE + M+ ++
Sbjct: 1710 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 688 ERQRD 692
+Q +
Sbjct: 1770 TQQAE 1774
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 72.0 bits (175), Expect = 2e-12
Identities = 147/737 (19%), Positives = 283/737 (38%), Gaps = 98/737 (13%)
Query: 5 STSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAI---------MNKF 55
ST+ Q + AK+++ +T +K+ ET A V +++ K A+ +
Sbjct: 1168 STATQQELR--AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA 1225
Query: 56 KVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKN-------------SENSSSRTEF 102
K ++ E+ L +L+ + K + K S+ +R E
Sbjct: 1226 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1285
Query: 103 QQII----NLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGK 158
+ N TGM+ + EG+ K+ D +L+ +L+ + L N
Sbjct: 1286 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ--DTQELLQEETRQKLNVST 1343
Query: 159 KLPQGESRSYEVMGSMEETL---CNIDDRDGNRNVHLEFTERESRKDGED-EFVKEMREE 214
KL Q E + ++E + N++ N+ L +S+K +D E EE
Sbjct: 1344 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS----DSKKKLQDFASTVEALEE 1399
Query: 215 RKFQKLKNKEEVLKASREEKVLMD--EGAVLTLVADLSSATLDISKQWSNVFNILRENDF 272
K + K E + + E+ D E L +L +D+ Q V N+ ++
Sbjct: 1400 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1459
Query: 273 EPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGI 332
+ L E K + + ++ ++ K ++ S+ L++ L KEE+ + + +
Sbjct: 1460 FDQLLAEEKNISSKYADERDRAEAEAREK-ETKALSLARALEEALEAKEELERTNK---M 1515
Query: 333 QEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEAS 392
+ + L+ SK G+ + L++ K A +M+ ++TQ LEEL++E
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHE------LEKSKRALETQMEEMKTQ------LEELEDELQ 1563
Query: 393 GMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEE--EEQTSEQDSTFQGHT 450
ED + LE + G E + + E++ L+ + E +T +D Q
Sbjct: 1564 ATEDAK--LRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1621
Query: 451 LVDAKHEVEITSDGMETTFIDSVEDSES----------------EEEEEGKSSETGKVKT 494
AK ++E +E +++ E E E+ ++S T
Sbjct: 1622 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFAT 1681
Query: 495 TSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQV-VHKTQEEEETAVPTSQGTGTPCLTL 553
EKKA + E L D + + Q + K + EE A S
Sbjct: 1682 AKENEKKA--KSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR 1739
Query: 554 CLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEET 613
L + LE +E + + ++S V K + E+ L TE T+++ + +
Sbjct: 1740 RLEARIAQLEEELEEEQGNME---AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1796
Query: 614 EENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEF 673
E + + + E++ G +KS S + LE +I LE+Q+E+
Sbjct: 1797 LERQNKELRSKLHEME---GAVKSK-------------FKSTIAALEAKIAQLEEQVEQE 1840
Query: 674 SKDTMQMTKQIISKERQ 690
+++ TK + K+++
Sbjct: 1841 AREKQAATKSLKQKDKK 1857
Score = 60.1 bits (144), Expect = 9e-09
Identities = 147/825 (17%), Positives = 332/825 (40%), Gaps = 141/825 (17%)
Query: 16 AKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEI------QDLMFEEM 69
AK+++ +T MK Q ++ A L L+ + K K L+++ +E+
Sbjct: 814 AKRQQQLTAMKVIQ-----RNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDEL 868
Query: 70 RETLKNDLKAVLGGKATIPEVKNSENSSSR-TEFQQIINLALQ-KTGMVGKIEGENSKIG 127
++T + KA E+K E S+ TE + ++ LQ +T + + E ++
Sbjct: 869 QKTKERQQKAE-------NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLA 921
Query: 128 DDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGN 187
K E+ E+ +++ E + G++L + + M +EE L ++
Sbjct: 922 AK------KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAAR 973
Query: 188 RNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVA 247
+ + LE E++ +K++ +E +N K S+E K+L +
Sbjct: 974 QKLQLEKVTAEAK-------IKKLEDEILVMDDQNN----KLSKERKLLEER-------- 1014
Query: 248 DLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSL-RKFASQK 306
+S T +++++ N+ + + + E+++ K E K+ +L+ L RK
Sbjct: 1015 -ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK--KEEKSRQELEKLKRKLEGDA 1071
Query: 307 SSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVA 366
S E + D+ Q E+ K + +K ++ EI + ++E++
Sbjct: 1072 SDFHEQIADLQAQIAEL-----KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH 1126
Query: 367 KPEEMKNLETQ-------EEEFSEL-EELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEE 418
+ ++L+++ E++ +L EEL+ + +ED D++ ++E L + E
Sbjct: 1127 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE------LRAKRE 1180
Query: 419 EEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSES 478
+E + L++ +E+T ++ Q A+ E+T + + D
Sbjct: 1181 QEVTVLKK-------ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK 1233
Query: 479 EEEEEGKSSETGKVKTTSLTEKKASRRQKEIP-----FSYLVGDSGKKKLVKHQVVHKTQ 533
+ E+ + G+++ +++ ++K++ D + + + VHK Q
Sbjct: 1234 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1293
Query: 534 EEEETAVPTSQGTGTPCLTLC--LASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEE 591
E E+ + L +AS S L+ + + ++ + L++ST KL++ EE
Sbjct: 1294 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST---KLRQLEE 1350
Query: 592 KKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDD 651
+++ L ++ +E + E K+ + H L I+ S D
Sbjct: 1351 ERN-------------SLQDQLDEEM---------EAKQNL----ERHISTLNIQLS--D 1382
Query: 652 LSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKE 711
++ +++LE+ + F K+ +T+Q K D E+++
Sbjct: 1383 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK------------- 1429
Query: 712 SYENRAEDIIKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKE 771
NR + + +++ + + + S+LE + K D+ ++I K+ + D
Sbjct: 1430 ---NRLQQELDDLVVDLDNQRQLVSNLE-----KKQRKFDQLLAEEKNISSKYADERD-- 1479
Query: 772 KIIRASRERREITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLE 816
RA E RE + + + +L+ + + + + K +E
Sbjct: 1480 ---RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521
Score = 55.1 bits (131), Expect = 3e-07
Identities = 132/665 (19%), Positives = 262/665 (39%), Gaps = 83/665 (12%)
Query: 68 EMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKT--GMVGKIEGENSK 125
E E LK +L+ L AT E++ + R + ++ AL + +++ K
Sbjct: 1153 EELEALKTELEDTLDSTATQQELR-----AKREQEVTVLKKALDEETRSHEAQVQEMRQK 1207
Query: 126 IGDDNENLTFKLE-VNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDR 184
E LT +LE LD + + L GE R V+G ++ +
Sbjct: 1208 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA-GELR---VLGQAKQEV-----E 1258
Query: 185 DGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREE------KVLMD 238
+ + + E +S+ + E+ + K KL+N+ E + E K+ D
Sbjct: 1259 HKKKKLEAQVQELQSKCSDGERARAELND--KVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 239 EGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQS 298
++ + + D + ++Q NV LR+ + E L + + D E++ +L+
Sbjct: 1317 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD-----QLDEEMEAKQNLER 1371
Query: 299 -LRKFASQKSSVKELLKDVLPQKEEINQGGRKYG------IQEKRDKT-----LIDSKHR 346
+ Q S K+ L+D E + +G +++ Q+ +K L +K+R
Sbjct: 1372 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431
Query: 347 AGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEE---ASGMEDDEDTSGL 403
+ D + L + V+ NLE ++ +F +L L EE +S D+ D +
Sbjct: 1432 LQQELDDLVVDLDNQRQLVS------NLEKKQRKFDQL--LAEEKNISSKYADERDRAEA 1483
Query: 404 EEEEEEPSGLE-----EEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEV 458
E E+E L EE E LE E E+ S +D + HE+
Sbjct: 1484 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN------VHEL 1537
Query: 459 EITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDS 518
E + +ET ++ ++ E E+E +++E K++ + + ++++ +
Sbjct: 1538 EKSKRALETQ-MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 519 GKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLS 578
+++L + ++T+ E+E Q L K LE+ D K +
Sbjct: 1597 KRRQLQRQLHEYETELEDER----KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 579 ISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSS 638
+ KL+ + R L + E T + E S+ + +++E++ + +
Sbjct: 1653 ---QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1709
Query: 639 HSGV-LEIENSVDDLSSRMD----------ILEERIDSLEDQIEEFSKDTMQMTKQIISK 687
LE E ++L+S + LE RI LE+++EE + M+ ++
Sbjct: 1710 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 688 ERQRD 692
+Q +
Sbjct: 1770 TQQAE 1774
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 72.0 bits (175), Expect = 2e-12
Identities = 147/737 (19%), Positives = 283/737 (38%), Gaps = 98/737 (13%)
Query: 5 STSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAI---------MNKF 55
ST+ Q + AK+++ +T +K+ ET A V +++ K A+ +
Sbjct: 1161 STATQQELR--AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA 1218
Query: 56 KVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKN-------------SENSSSRTEF 102
K ++ E+ L +L+ + K + K S+ +R E
Sbjct: 1219 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1278
Query: 103 QQII----NLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGK 158
+ N TGM+ + EG+ K+ D +L+ +L+ + L N
Sbjct: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ--DTQELLQEETRQKLNVST 1336
Query: 159 KLPQGESRSYEVMGSMEETL---CNIDDRDGNRNVHLEFTERESRKDGED-EFVKEMREE 214
KL Q E + ++E + N++ N+ L +S+K +D E EE
Sbjct: 1337 KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS----DSKKKLQDFASTVEALEE 1392
Query: 215 RKFQKLKNKEEVLKASREEKVLMD--EGAVLTLVADLSSATLDISKQWSNVFNILRENDF 272
K + K E + + E+ D E L +L +D+ Q V N+ ++
Sbjct: 1393 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1452
Query: 273 EPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGI 332
+ L E K + + ++ ++ K ++ S+ L++ L KEE+ + + +
Sbjct: 1453 FDQLLAEEKNISSKYADERDRAEAEAREK-ETKALSLARALEEALEAKEELERTNK---M 1508
Query: 333 QEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEAS 392
+ + L+ SK G+ + L++ K A +M+ ++TQ LEEL++E
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHE------LEKSKRALETQMEEMKTQ------LEELEDELQ 1556
Query: 393 GMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEE--EEQTSEQDSTFQGHT 450
ED + LE + G E + + E++ L+ + E +T +D Q
Sbjct: 1557 ATEDAK--LRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1614
Query: 451 LVDAKHEVEITSDGMETTFIDSVEDSES----------------EEEEEGKSSETGKVKT 494
AK ++E +E +++ E E E+ ++S T
Sbjct: 1615 AAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFAT 1674
Query: 495 TSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQV-VHKTQEEEETAVPTSQGTGTPCLTL 553
EKKA + E L D + + Q + K + EE A S
Sbjct: 1675 AKENEKKA--KSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR 1732
Query: 554 CLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEET 613
L + LE +E + + ++S V K + E+ L TE T+++ + +
Sbjct: 1733 RLEARIAQLEEELEEEQGNME---AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1789
Query: 614 EENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEF 673
E + + + E++ G +KS S + LE +I LE+Q+E+
Sbjct: 1790 LERQNKELRSKLHEME---GAVKSK-------------FKSTIAALEAKIAQLEEQVEQE 1833
Query: 674 SKDTMQMTKQIISKERQ 690
+++ TK + K+++
Sbjct: 1834 AREKQAATKSLKQKDKK 1850
Score = 60.1 bits (144), Expect = 9e-09
Identities = 147/825 (17%), Positives = 332/825 (40%), Gaps = 141/825 (17%)
Query: 16 AKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEI------QDLMFEEM 69
AK+++ +T MK Q ++ A L L+ + K K L+++ +E+
Sbjct: 807 AKRQQQLTAMKVIQ-----RNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDEL 861
Query: 70 RETLKNDLKAVLGGKATIPEVKNSENSSSR-TEFQQIINLALQ-KTGMVGKIEGENSKIG 127
++T + KA E+K E S+ TE + ++ LQ +T + + E ++
Sbjct: 862 QKTKERQQKAE-------NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLA 914
Query: 128 DDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGN 187
K E+ E+ +++ E + G++L + + M +EE L ++
Sbjct: 915 AK------KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAAR 966
Query: 188 RNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVA 247
+ + LE E++ +K++ +E +N K S+E K+L +
Sbjct: 967 QKLQLEKVTAEAK-------IKKLEDEILVMDDQNN----KLSKERKLLEER-------- 1007
Query: 248 DLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSL-RKFASQK 306
+S T +++++ N+ + + + E+++ K E K+ +L+ L RK
Sbjct: 1008 -ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK--KEEKSRQELEKLKRKLEGDA 1064
Query: 307 SSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVA 366
S E + D+ Q E+ K + +K ++ EI + ++E++
Sbjct: 1065 SDFHEQIADLQAQIAEL-----KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH 1119
Query: 367 KPEEMKNLETQ-------EEEFSEL-EELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEE 418
+ ++L+++ E++ +L EEL+ + +ED D++ ++E L + E
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE------LRAKRE 1173
Query: 419 EEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSES 478
+E + L++ +E+T ++ Q A+ E+T + + D
Sbjct: 1174 QEVTVLKK-------ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK 1226
Query: 479 EEEEEGKSSETGKVKTTSLTEKKASRRQKEIP-----FSYLVGDSGKKKLVKHQVVHKTQ 533
+ E+ + G+++ +++ ++K++ D + + + VHK Q
Sbjct: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
Query: 534 EEEETAVPTSQGTGTPCLTLC--LASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEE 591
E E+ + L +AS S L+ + + ++ + L++ST KL++ EE
Sbjct: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST---KLRQLEE 1343
Query: 592 KKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDD 651
+++ L ++ +E + E K+ + H L I+ S D
Sbjct: 1344 ERN-------------SLQDQLDEEM---------EAKQNL----ERHISTLNIQLS--D 1375
Query: 652 LSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKE 711
++ +++LE+ + F K+ +T+Q K D E+++
Sbjct: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK------------- 1422
Query: 712 SYENRAEDIIKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKE 771
NR + + +++ + + + S+LE + K D+ ++I K+ + D
Sbjct: 1423 ---NRLQQELDDLVVDLDNQRQLVSNLE-----KKQRKFDQLLAEEKNISSKYADERD-- 1472
Query: 772 KIIRASRERREITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLE 816
RA E RE + + + +L+ + + + + K +E
Sbjct: 1473 ---RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514
Score = 55.1 bits (131), Expect = 3e-07
Identities = 132/665 (19%), Positives = 262/665 (39%), Gaps = 83/665 (12%)
Query: 68 EMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKT--GMVGKIEGENSK 125
E E LK +L+ L AT E++ + R + ++ AL + +++ K
Sbjct: 1146 EELEALKTELEDTLDSTATQQELR-----AKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
Query: 126 IGDDNENLTFKLE-VNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDR 184
E LT +LE LD + + L GE R V+G ++ +
Sbjct: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA-GELR---VLGQAKQEV-----E 1251
Query: 185 DGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREE------KVLMD 238
+ + + E +S+ + E+ + K KL+N+ E + E K+ D
Sbjct: 1252 HKKKKLEAQVQELQSKCSDGERARAELND--KVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 239 EGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQS 298
++ + + D + ++Q NV LR+ + E L + + D E++ +L+
Sbjct: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD-----QLDEEMEAKQNLER 1364
Query: 299 -LRKFASQKSSVKELLKDVLPQKEEINQGGRKYG------IQEKRDKT-----LIDSKHR 346
+ Q S K+ L+D E + +G +++ Q+ +K L +K+R
Sbjct: 1365 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424
Query: 347 AGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEE---ASGMEDDEDTSGL 403
+ D + L + V+ NLE ++ +F +L L EE +S D+ D +
Sbjct: 1425 LQQELDDLVVDLDNQRQLVS------NLEKKQRKFDQL--LAEEKNISSKYADERDRAEA 1476
Query: 404 EEEEEEPSGLE-----EEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEV 458
E E+E L EE E LE E E+ S +D + HE+
Sbjct: 1477 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN------VHEL 1530
Query: 459 EITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDS 518
E + +ET ++ ++ E E+E +++E K++ + + ++++ +
Sbjct: 1531 EKSKRALETQ-MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 519 GKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLS 578
+++L + ++T+ E+E Q L K LE+ D K +
Sbjct: 1590 KRRQLQRQLHEYETELEDER----KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 579 ISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSS 638
+ KL+ + R L + E T + E S+ + +++E++ + +
Sbjct: 1646 ---QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702
Query: 639 HSGV-LEIENSVDDLSSRMD----------ILEERIDSLEDQIEEFSKDTMQMTKQIISK 687
LE E ++L+S + LE RI LE+++EE + M+ ++
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 688 ERQRD 692
+Q +
Sbjct: 1763 TQQAE 1767
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 71.2 bits (173), Expect = 4e-12
Identities = 147/744 (19%), Positives = 298/744 (40%), Gaps = 112/744 (15%)
Query: 5 STSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAI---------MNKF 55
ST+ Q + +K+++ + +K+ E A + +++ K A+ +
Sbjct: 1154 STAAQQELR--SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRV 1211
Query: 56 KVLMEIQDLMFEEMRETLKNDLKAVLGGKATIP-------------EVKNSENSSSRTEF 102
K +E E R L N++K +L GK +VK +E RTE
Sbjct: 1212 KANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTEL 1271
Query: 103 -QQIINLALQK---TGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGK 158
++ L ++ TG++ + + ++SK+ D L +L+ + + +N + + +
Sbjct: 1272 ADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKL 1331
Query: 159 KLPQGESRSY-EVMGSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEF-VKEMREERK 216
K + E S+ E + EE N++ + + + + +K ED E EE K
Sbjct: 1332 KQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVA----DMKKKMEDSVGCLETAEEVK 1387
Query: 217 FQKLKNKEEVLKASREEKVLMDEGAVLT---LVADLSSATLDISKQWSNVFNILRENDFE 273
+KL+ E L EEKV + T L +L +D+ Q + N+ ++
Sbjct: 1388 -RKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKF 1446
Query: 274 PKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQ 333
+ L E K E + ++ ++ K ++ S+ L++ + QK E+ + +++ +
Sbjct: 1447 DQLLAEEKTISAKYAEERDRAEAEAREK-ETKALSLARALEEAMEQKAELERLNKQFRTE 1505
Query: 334 EKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASG 393
+ L+ SK G+ + L++ K A ++++ ++TQ LEEL++E
Sbjct: 1506 ME---DLMSSKDDVGKSVHE------LEKSKRALEQQVEEMKTQ------LEELEDELQA 1550
Query: 394 MED-----DEDTSGLEEE-EEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQ 447
ED + + ++ + E + G +E+ EE+ L + E + +D Q
Sbjct: 1551 TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR------QVREMEAELEDERKQ 1604
Query: 448 GHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETG-KVKTTSLTEKKASRRQ 506
V A+ ++E+ +E IDS + E ++ + + K L + +ASR +
Sbjct: 1605 RSMAVAARKKLEMDLKDLEA-HIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREE 1663
Query: 507 KEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSH 566
L +K +K Q +EE A A+ +
Sbjct: 1664 ------ILAQAKENEKKLKSMEAEMIQLQEELA----------------AAERAKRQAQQ 1701
Query: 567 DEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIR 626
+ + S G L++ + R EE +E TE + L+ + + I
Sbjct: 1702 ERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQ-ID 1760
Query: 627 EIKEEIGNLKSSHSG-------------------VLEIENSVDD-LSSRMDILEERIDSL 666
+I ++ NL+ SH+ + E+E +V + + LE +I L
Sbjct: 1761 QINTDL-NLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL 1819
Query: 667 EDQIEEFSKDTMQMTKQIISKERQ 690
E+Q++ +K+ KQ+ E++
Sbjct: 1820 EEQLDNETKERQAACKQVRRTEKK 1843
Score = 51.2 bits (121), Expect = 4e-06
Identities = 147/802 (18%), Positives = 323/802 (40%), Gaps = 101/802 (12%)
Query: 17 KKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFK---VLMEIQDLMFEEMRETL 73
KKK + E+ E ++ L L+ A + K + +++E Q+ + ++ L
Sbjct: 938 KKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLL 997
Query: 74 KNDLKAVLGGKATIPEVKNSENSSSRTEFQQIIN-------------LALQKTGMVGKIE 120
++ + A T E K+ + + + + +I L+KT K+E
Sbjct: 998 EDRI-AEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRR--KLE 1054
Query: 121 GENSKIGDDNENLTFKL---------EVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVM 171
G+++ + D L ++ + EL L E + L + E+
Sbjct: 1055 GDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL----KKIRELE 1110
Query: 172 GSMEETLCNIDDRDGNRNVHLEFTERESRKDGED------EFVKEMREERKFQKLKNKEE 225
+ E +++ +RN E++ R GE+ E + Q+L++K E
Sbjct: 1111 SQISELQEDLESERASRNK----AEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKRE 1166
Query: 226 ----VLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVK 281
+LK + EE+ E + + S A ++++Q + + N + K E +
Sbjct: 1167 QEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRV-KANLEKAKQTLENE 1225
Query: 282 LAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLI 341
+ E+K LQ ++ V+ L+++ + + N+G +R +T +
Sbjct: 1226 RG-ELANEVKVL--LQGKGDSEHKRKKVEAQLQEL---QVKFNEG--------ERVRTEL 1271
Query: 342 DSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTS 401
K ++ D ++ L L + + K+ E + + +EL +E + + T
Sbjct: 1272 ADKVTKLQVELDNVTGL-LSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
Query: 402 GLEEEEEEPSGLEE-EEEEEASGLEEDEASGLEEE--EEQTSEQDSTFQGHTLVDAKHEV 458
+ E+E+ S E+ EEEEEA E + + L + + + +DS T + K ++
Sbjct: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL 1390
Query: 459 EITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASR---RQKEIPFSYLV 515
+ +G+ + V + E+ + + + L ++ S +K+ F L+
Sbjct: 1391 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLL 1450
Query: 516 GDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHT 575
+ + + K EE + A ++ T L+L +++LE + ++ +
Sbjct: 1451 AE-------EKTISAKYAEERDRAEAEAREKETKALSL-----ARALEEAMEQKAELERL 1498
Query: 576 NLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNL 635
N T + L +++ +++H EL + L ++ EE + + E+++E L
Sbjct: 1499 NKQFRTEMEDLMSSKDDVGKSVH--ELEKSKRALEQQVEE-----MKTQLEELEDE---L 1548
Query: 636 KSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEE 695
+++ L +E ++ + ++ E + ++Q EE K Q+ +Q+ E + + E
Sbjct: 1549 QATEDAKLRLEVNLQAMKAQ---FERDLQGRDEQSEEKKK---QLVRQVREMEAELEDER 1602
Query: 696 RSRSCNIRLIGIPEKESYENRAE-DIIKEIIDENFAELKKGSSLEIVSACRVPSKIDEKR 754
+ RS + E + + A D + DE +L+K ++ R ++D+ R
Sbjct: 1603 KQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK-LQAQMKDCMR---ELDDTR 1658
Query: 755 LTPRHILVKFWNSSDKEKIIRA 776
+ IL + + K K + A
Sbjct: 1659 ASREEILAQAKENEKKLKSMEA 1680
Score = 44.7 bits (104), Expect = 4e-04
Identities = 77/382 (20%), Positives = 166/382 (43%), Gaps = 44/382 (11%)
Query: 362 EVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDT------SGLEEEEEEPSGLEE 415
++ K + + L+ + E +E EEL + + + + + +EEEEE L+
Sbjct: 877 QLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQA 936
Query: 416 EEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVED 475
E+++ ++E EEQ E++S Q L E ++ E + ED
Sbjct: 937 EKKK--------MQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL---ED 985
Query: 476 SESEEEEEGKSSETGKVK-TTSLT---EKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHK 531
+ +E K E + TT+LT EK S + + ++ D +++L + + K
Sbjct: 986 QNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDL-EERLRREE---K 1041
Query: 532 TQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEE 591
++E E +G T ++ E+ KK + + ++++
Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE----ELQAALARVEEEAA 1097
Query: 592 KKHRTL-HTEELTSKEADLTE--ETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENS 648
+K+ L EL S+ ++L E E+E R+ R++ EE+ LK+ E+E++
Sbjct: 1098 QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKT------ELEDT 1151
Query: 649 VDDLSSRMDI---LEERIDSLEDQIEEFSKD---TMQMTKQIISKERQRDIEERSRSCNI 702
+D +++ ++ E+ ++ L+ +EE +K +Q +Q S+ + E+ ++ +
Sbjct: 1152 LDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRV 1211
Query: 703 RLIGIPEKESYENRAEDIIKEI 724
+ K++ EN ++ E+
Sbjct: 1212 KANLEKAKQTLENERGELANEV 1233
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 71.2 bits (173), Expect = 4e-12
Identities = 174/870 (20%), Positives = 354/870 (40%), Gaps = 117/870 (13%)
Query: 1 MSDVSTSVQSKFARLAKKKENITYMKR---EQLTETDKDIAPVLDLKCKDVSAIMNKFKV 57
+ + T V+ + + +K + + K EQL + A +++ + + ++
Sbjct: 864 VKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEI 923
Query: 58 LMEIQDLMFEE--MRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKT-- 113
L +++ + EE + L+N+ K + + E + E + + L L+K
Sbjct: 924 LHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQ-------KLQLEKVTA 976
Query: 114 -GMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMG 172
+ K+E E + D N + ++ E D E +S ++ + ++ + ++
Sbjct: 977 EAKIKKMEEEILLLEDQNSKFIKEKKLME-----DRIAECSSQLAEEEEKAKNLA-KIRN 1030
Query: 173 SMEETLCNIDDRDGNRNVHLEFTERESRK-DGE----DEFVKEMR---EERKFQKLKNKE 224
E + ++++R + E+ RK DGE + + E++ +E K Q K +E
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1090
Query: 225 EVLKA-SREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLA 283
E+ A +R + + + L +V +L + ++ + + + + + + + L E A
Sbjct: 1091 ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEA 1150
Query: 284 FKCDGE--IKTFSDLQSLR-----KFASQKSSVKELLKDVLPQ---------------KE 321
K + E + T + Q LR + A K +++E K+ Q E
Sbjct: 1151 LKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSE 1210
Query: 322 EINQGGR-KYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEE 380
++ Q R K +++ + D+K A E+ L++VK + K L+ Q +E
Sbjct: 1211 QLEQAKRFKANLEKNKQGLETDNKELACEVK-------VLQQVKAESEHKRKKLDAQVQE 1263
Query: 381 FSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTS 440
+ + + +E E S L+ E + S L EE E++ +D AS LE + + T
Sbjct: 1264 L-HAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAAS-LESQLQDTQ 1321
Query: 441 E--QDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLT 498
E Q+ T Q L ++E + S+++ + EEEE K+ E + S
Sbjct: 1322 ELLQEETRQKLNLSSRIRQLEEEKN--------SLQEQQEEEEEARKNLEKQVLALQSQL 1373
Query: 499 EKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASP 558
+ ++ + ++ KK L + + + EE+ A + T L
Sbjct: 1374 ADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNR-----LQQE 1428
Query: 559 SKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTE-ETEENL 617
L + D H++ +NL EEK + EE EA+ E ET+
Sbjct: 1429 LDDLTVDLD-HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALS 1487
Query: 618 RSSVINSIREIKEEIGNL-KSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFS-- 674
+ + E KEE K + + ++ +S DD+ + LE+ +LE Q+EE
Sbjct: 1488 LARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQ 1547
Query: 675 ----KDTMQMTK----------QIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDI 720
+D +Q T+ Q + + +RD++ R E E + +
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRD-------------EQNEEKKRLL 1594
Query: 721 IKEI--IDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASR 778
IK++ ++ + +K +L + S ++ +ID K L + ++ N + ++++I+ R
Sbjct: 1595 IKQVRELEAELEDERKQRALAVASKKKM--EIDLKDLEAQ---IEAANKA-RDEVIKQLR 1648
Query: 779 ERREITYQGTRIRLTADLSLDTLDARSKWS 808
+ + R A S D + A+SK S
Sbjct: 1649 KLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Score = 65.9 bits (159), Expect = 2e-10
Identities = 158/793 (19%), Positives = 306/793 (38%), Gaps = 114/793 (14%)
Query: 10 SKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEM 69
SKF + K E+ QL E ++ K K+++ I NK Q++M ++
Sbjct: 995 SKFIKEKKLMEDRIAECSSQLAEEEE--------KAKNLAKIRNK-------QEVMISDL 1039
Query: 70 RETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQ--------QIINLALQKTGMVGKIEG 121
E LK + K + + + K + + T+ Q QI L LQ +++G
Sbjct: 1040 EERLKKEEKT----RQELEKAKRKLDGET-TDLQDQIAELQAQIDELKLQLAKKEEELQG 1094
Query: 122 ENSKIGDD---NENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETL 178
++ GDD ++N K+ V EL ++ E ++ + E + ++ +E
Sbjct: 1095 ALAR-GDDETLHKNNALKV-VRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALK 1152
Query: 179 CNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMD 238
++D E R R+ E K + EE K ++ ++ + ++
Sbjct: 1153 TELEDTLDTTAAQQEL--RTKREQEVAELKKALEEETK----NHEAQIQDMRQRHATALE 1206
Query: 239 EGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAF-----KCDGEIKTF 293
E + A A L+ +KQ N +E E K L +VK K D +++
Sbjct: 1207 ELSEQLEQAKRFKANLEKNKQGLETDN--KELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264
Query: 294 ----SDLQSLR-KFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKR-DKTLIDSKHRA 347
S+ LR + A + S ++ L +V EE + G K+ + L D++
Sbjct: 1265 HAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELL 1324
Query: 348 GEITSDGLSFLFLKEVKVAKPEEMKNL--ETQEEEFSELEELDEEASGMED--------- 396
E T L+ ++ + EE KN E QEEE + L+++ ++
Sbjct: 1325 QEETRQKLNL----SSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380
Query: 397 DEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKH 456
D+D +E EE L ++ E + LEE + ++ E+T + VD H
Sbjct: 1381 DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA--YDKLEKTKNRLQQELDDLTVDLDH 1438
Query: 457 EVEITSD----------------GMETTFIDSVEDSESE-EEEEGKSSETGKVKTTSLTE 499
+ ++ S+ + + + + +E+E E+E K+ + +L
Sbjct: 1439 QRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEA 1498
Query: 500 KKASRRQKEIPFSYL-------------VGDSGKKKLVKHQVVHKTQEEEETAVPTSQGT 546
K+ RQ + + + V + K K Q V + + + E Q T
Sbjct: 1499 KEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
Query: 547 GTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTE-----EKKHRTLHTEE 601
L L + + + D + + ++++ E E+K R L
Sbjct: 1559 EDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVAS 1618
Query: 602 LTSKEADLTE-----ETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRM 656
E DL + E R VI +R+++ + +K + E S D++ ++
Sbjct: 1619 KKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQ---MKDYQRELEEARASRDEIFAQS 1675
Query: 657 DILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRD--IEERSRSCNIRLIGIPEKESYE 714
E+++ SLE +I + ++ + E++RD +E + S + + + EK E
Sbjct: 1676 KESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLE 1735
Query: 715 NRAEDIIKEIIDE 727
R + +E+ +E
Sbjct: 1736 ARIAQLEEELEEE 1748
Score = 62.0 bits (149), Expect = 2e-09
Identities = 141/724 (19%), Positives = 297/724 (41%), Gaps = 94/724 (12%)
Query: 17 KKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLM--FEEMRETLK 74
K+++ + +K+ ET A + D++ + +A+ + L + + E+ ++ L+
Sbjct: 1171 KREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLE 1230
Query: 75 NDLKAVLGGKATIPEVK-NSENSSSR--TEFQQIINLALQKTGMVGKIEGENSKIGDDNE 131
D K + + +VK SE+ + + Q++ + + ++ + SK+ ++ +
Sbjct: 1231 TDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290
Query: 132 NLTFKLEVNELSG----KLDNTNEYNSNDGKKLPQGESRSYEVMGS----MEETLCNI-- 181
N++ LE E G K + E D ++L Q E+R + S +EE ++
Sbjct: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350
Query: 182 ---DDRDGNRNVHLEFTERES------RKDGEDEFVKEMREERKFQKLKNKEEVLKASRE 232
++ + +N+ + +S +K +D E EE K + LK+ E + + E
Sbjct: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410
Query: 233 EKVLMD--EGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEI 290
+ + D E L +L T+D+ Q N+ ++ + L E K E
Sbjct: 1411 KALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEE 1470
Query: 291 KTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRD-KTLIDSKHRAGE 349
+ ++ ++ K ++ S+ L++ L KEE + + Q + D + L+ SK G+
Sbjct: 1471 RDRAEAEAREK-ETKALSLARALEEALEAKEEFERQNK----QLRADMEDLMSSKDDVGK 1525
Query: 350 ITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMED-----DEDTSGLE 404
+ L++ K A ++++ + TQ LEEL++E ED + + ++
Sbjct: 1526 NVHE------LEKSKRALEQQVEEMRTQ------LEELEDELQATEDAKLRLEVNMQAMK 1573
Query: 405 EEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDG 464
+ E +E+ EE L + LE E E +Q + V +K ++EI
Sbjct: 1574 AQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRAL-----AVASKKKMEIDLKD 1628
Query: 465 METTFIDSVEDSESE-----------------EEEEGKSSETGKVKTTSLTEKKASRRQK 507
+E I++ + E E EE ++S + +EKK +
Sbjct: 1629 LEAQ-IEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEA 1687
Query: 508 EIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHD 567
EI L + + + H QE +E A + L ++ +
Sbjct: 1688 EI--LQLQEELASSERARR---HAEQERDELADEITNSASGKSALLDEKRRLEARIAQLE 1742
Query: 568 EHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIRE 627
E + +N+ + + +KT T ++ + A+L E +S N+ ++
Sbjct: 1743 EELEEEQSNMELLND--RFRKT---------TLQVDTLNAELAAERSAAQKSD--NARQQ 1789
Query: 628 IKEEIGNLKSSHSGVLEIENSVDD-LSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIIS 686
++ + LK+ + E+E +V + + LE +I LE+Q+E+ +K+ K +
Sbjct: 1790 LERQNKELKAK---LQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRR 1846
Query: 687 KERQ 690
E++
Sbjct: 1847 TEKK 1850
Score = 53.1 bits (126), Expect = 1e-06
Identities = 155/716 (21%), Positives = 290/716 (40%), Gaps = 131/716 (18%)
Query: 16 AKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKN 75
AKK++ ++ +K Q ++ A L L+ + K K L+++ E L+
Sbjct: 807 AKKQQQLSALKVLQ-----RNCAAYLKLRHWQWWRVFTKVKPLLQVT-----RQEEELQA 856
Query: 76 DLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNEN--- 132
+ +L K +V+ R + QQ++ +K + +++ E + E
Sbjct: 857 KDEELLKVKEKQTKVEGELEEMER-KHQQLLE---EKNILAEQLQAETELFAEAEEMRAR 912
Query: 133 -LTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRN-V 190
K E+ E+ L++ E + L + + + +EE L D+ +G R +
Sbjct: 913 LAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL---DEEEGARQKL 969
Query: 191 HLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLS 250
LE E++ +K+M EE + +N + + +EK LM++ +A+ S
Sbjct: 970 QLEKVTAEAK-------IKKMEEEILLLEDQNSKFI-----KEKKLMEDR-----IAECS 1012
Query: 251 SATLDISKQWSNVFNILRE-----NDFEPKFLCEVKLAF-------KCDGEIKTFSDLQS 298
S + ++ N+ I + +D E + E K K DGE +DLQ
Sbjct: 1013 SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET---TDLQD 1069
Query: 299 LRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSD-GLSF 357
+ A ++ + EL K L +KEE QG G D+TL K+ A ++ +
Sbjct: 1070 --QIAELQAQIDEL-KLQLAKKEEELQGALARG----DDETL--HKNNALKVVRELQAQI 1120
Query: 358 LFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEE-----EEEPSG 412
L+E ++ E Q+ + SE EL+ + +ED DT+ ++E E+E +
Sbjct: 1121 AELQEDFESEKASRNKAEKQKRDLSE--ELEALKTELEDTLDTTAAQQELRTKREQEVAE 1178
Query: 413 LEEEEEEEASGLE-------EDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGM 465
L++ EEE E + A+ LEE EQ EQ F K +E G+
Sbjct: 1179 LKKALEEETKNHEAQIQDMRQRHATALEELSEQL-EQAKRF--------KANLEKNKQGL 1229
Query: 466 ETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVK 525
ET + + + ++ + +S KK + +E+ GD + +L +
Sbjct: 1230 ETDNKELACEVKVLQQVKAESEHK---------RKKLDAQVQELHAKVSEGDRLRVELAE 1280
Query: 526 HQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTK 585
K Q E + TL + K ++ + D S +
Sbjct: 1281 K--ASKLQNELDNVS-----------TLLEEAEKKGIKFAKDAASLES-----------Q 1316
Query: 586 LKKTEEK-KHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNL-KSSHSGVL 643
L+ T+E + T L+S+ L EE NS++E +EE K+ VL
Sbjct: 1317 LQDTQELLQEETRQKLNLSSRIRQLEEEK---------NSLQEQQEEEEEARKNLEKQVL 1367
Query: 644 EIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRS 699
+++ + D ++D I+SLE+ ++ KD +++++ K D E++++
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKN 1423
Score = 33.1 bits (74), Expect = 1.1
Identities = 41/157 (26%), Positives = 75/157 (47%), Gaps = 13/157 (8%)
Query: 585 KLKKTEEKKHRTL-HTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVL 643
+L K +EK+ + EE+ K L EE +N+ + + + E+ E +++ +
Sbjct: 860 ELLKVKEKQTKVEGELEEMERKHQQLLEE--KNILAEQLQAETELFAEAEEMRARLAAKK 917
Query: 644 -EIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNI 702
E+E + DL SR++ EER +QI + K MQ I E Q D EE +R +
Sbjct: 918 QELEEILHDLESRVEEEEER-----NQILQNEKKKMQ--AHIQDLEEQLDEEEGARQ-KL 969
Query: 703 RLIGIPEKESYENRAEDIIKEIIDENFAELKKGSSLE 739
+L + + + E+I+ + D+N +K+ +E
Sbjct: 970 QLEKVTAEAKIKKMEEEILL-LEDQNSKFIKEKKLME 1005
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 70.9 bits (172), Expect = 5e-12
Identities = 140/726 (19%), Positives = 294/726 (40%), Gaps = 126/726 (17%)
Query: 7 SVQSKFARLAKKKENITYMKREQLTET-DKDIAPVLD---------LKCKDVSAIMNKFK 56
++++K ++ K+KEN R +L + D+ + + D +K K++ + K
Sbjct: 683 ALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCN 742
Query: 57 VLMEIQDLMFEEMRETLKNDL------KAVLGGKATIPEVKNSENSSSRTEFQQIINLAL 110
++ D +++ T + L KA GK+ + +++ ++ + QI +L +
Sbjct: 743 EQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEK----QIKHLEI 798
Query: 111 QKTGMVGK-------IEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQG 163
+K K ++G K+ + ENL+ EV+++ L+ + +K +
Sbjct: 799 EKNAESSKASSITRELQGRELKLTNLQENLS---EVSQVKETLEKELQILK---EKFAEA 852
Query: 164 ESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTE--RESRKDGEDEFVKEMREERKFQKLK 221
+ V SM+ET+ + ++ N+ E RE+ D E +F + ++ER+ Q +K
Sbjct: 853 SEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFRE--KDEREEQLIK 910
Query: 222 NKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVK 281
K EK+ D ++ + D SS ++ + L+E D E E++
Sbjct: 911 AK---------EKLENDIAEIMKMSGDNSSQLTKMNDELR-----LKERDVE-----ELQ 951
Query: 282 LAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLI 341
L L K S +++ ++D+ + E+ Q K +EK
Sbjct: 952 L---------------KLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEK------ 990
Query: 342 DSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTS 401
KE++ + K +ET + EL+ E A+ E +
Sbjct: 991 -------------------KELERKLSDLEKKMETSHNQCQELKARYERAT----SETKT 1027
Query: 402 GLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVE-I 460
EE + + E++ G E+ + L+E EE + D T DA +E +
Sbjct: 1028 KHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQM 1087
Query: 461 TSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGK 520
T + ET + S+ED++ + +E +K +L + + KE+
Sbjct: 1088 TKEKTET--LASLEDTKQTNAK--LQNELDTLKENNLKNVEELNKSKEL----------- 1132
Query: 521 KKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSIS 580
V++Q + + ++E ET + L + + E+ + SH L
Sbjct: 1133 -LTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEE 1191
Query: 581 TGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVIN----SIREIKEEIGNLK 636
V + E KK + ++ ++A L + ++ S+++ + +++ E+ L+
Sbjct: 1192 RSVLNNQLLEMKKRESKFIKDADEEKASLQKSI--SITSALLTEKDAELEKLRNEVTVLR 1249
Query: 637 SSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEER 696
++ + + V L S LE ++ +LE Q++E + Q++ + + Q D +ER
Sbjct: 1250 GENASAKSLHSVVQTLESDKVKLELKVKNLELQLKE---NKRQLSSSSGNTDTQADEDER 1306
Query: 697 SRSCNI 702
++ I
Sbjct: 1307 AQESQI 1312
Score = 52.0 bits (123), Expect = 2e-06
Identities = 152/798 (19%), Positives = 307/798 (38%), Gaps = 171/798 (21%)
Query: 62 QDLMFEEMR-ETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIE 120
Q L+FE+ + + L+ +L+ AT+ E S E ++ + L +Q+ + +
Sbjct: 471 QSLLFEKTKADKLQRELEDTR--VATVSE------KSRIMELEKDLALRVQEVAELRRRL 522
Query: 121 GENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCN 180
N GD + +L+ E++ L KL+ T + + L + E + L
Sbjct: 523 ESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYT 582
Query: 181 IDDRDGNRNVHLEFTERESRKDGED----------------------------------- 205
++ N L+ + K+ D
Sbjct: 583 ATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTET 642
Query: 206 -EF------VKEMR--EERKFQKLKNKE-----------EVLKASREEKVLMDEGAVLTL 245
EF +++MR + + + L+N++ E L+A + + E ++ +
Sbjct: 643 AEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAI 702
Query: 246 VADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFS----------- 294
+ L A + + N L+E + + K L EV L KC+ + K
Sbjct: 703 RSKLDKAEDQHLVEMEDTLNKLQEAEIKVKEL-EV-LQAKCNEQTKVIDNFTSQLKATEE 760
Query: 295 ---DLQSLRKFASQ-KSSVKELLKDVLPQKEEINQ-------------------GGRKY- 330
DL +LRK +S+ KS +K+L + + +++I GR+
Sbjct: 761 KLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELK 820
Query: 331 ------------GIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQE 378
++E +K L K + E + + +S V+ + E + L +E
Sbjct: 821 LTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVS------VQRSMQETVNKLHQKE 874
Query: 379 EEF----SELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEE 434
E+F S+LE+L E + ME E++E E ++ +E+ E E + SG +
Sbjct: 875 EQFNMLSSDLEKLRENLADME----AKFREKDEREEQLIKAKEKLENDIAEIMKMSG--D 928
Query: 435 EEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFID-SVED----SESEEEEEGKSSET 489
Q ++ + + + ++++T +F+ S+ED +E ++E K E
Sbjct: 929 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 988
Query: 490 GKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTP 549
K + E+K S +K++ S+ K + + KT+ EE
Sbjct: 989 EKKE----LERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEE------------- 1031
Query: 550 CLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADL 609
L + K+L + D+ K N + + +L+K +K E+ +
Sbjct: 1032 ----ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQM 1087
Query: 610 TEETEENLRS--SVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLE 667
T+E E L S + +++ E+ LK ++ +E N +L + + ++++
Sbjct: 1088 TKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKEL---LTVENQKMEEFR 1144
Query: 668 DQIEEFSKDTMQMTKQI--ISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDIIKEII 725
+IE + Q ++Q+ + +E + EE RS + E S++ E+ + ++
Sbjct: 1145 KEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRD-------EVTSHQKLEEE--RSVL 1195
Query: 726 DENFAELKKGSSLEIVSA 743
+ E+KK S I A
Sbjct: 1196 NNQLLEMKKRESKFIKDA 1213
Score = 49.3 bits (116), Expect = 2e-05
Identities = 133/635 (20%), Positives = 251/635 (39%), Gaps = 119/635 (18%)
Query: 113 TGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMG 172
T VG+IE E + D ++ V EL K+D + + E++
Sbjct: 382 TSHVGEIEQELALARDGHDQ-----HVLELEAKMDQLRTM-------VEAADREKVELLN 429
Query: 173 SMEETLCNIDDRDGNRNVHLEF-TERESRKDGEDEF--------VKEMREERKFQKLKNK 223
+EE ++D L+F E ES G+ E +KE+ + F+K K
Sbjct: 430 QLEEEKRKVED--------LQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEKTK-A 480
Query: 224 EEVLKASREEKV--LMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVK 281
+++ + + +V + ++ ++ L DL+ ++++ LR K +V
Sbjct: 481 DKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAE--------LRRRLESNKPAGDVD 532
Query: 282 LAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRK--YGIQEKRDK- 338
++ EI + + + + Q+ LK+ +EE +Q K Y EK K
Sbjct: 533 MSLSLLQEISSLQEKLEVTRTDHQREITS--LKEHFGAREETHQKEIKALYTATEKLSKE 590
Query: 339 --TLIDSKHRAGEITSDGLSFLFLK-EVKVAKPEEM---------KNLETQEEEFSELE- 385
+L A + SD ++ K E +A ++ K L T+ EF+EL+
Sbjct: 591 NESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKT 650
Query: 386 -----ELD-----EEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEE 435
LD E +D E + +E E + L + +E+ + LE + + E
Sbjct: 651 QIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAE 710
Query: 436 EEQTSEQDSTFQGHTLVDAK-HEVEITSD--GMETTFIDSVEDSESEEEEEGKSSET-GK 491
++ E + T + K E+E+ +T ID+ EE+ + K
Sbjct: 711 DQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRK 770
Query: 492 VKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCL 551
+ +E K R+Q E +K +KH + K E + + T + G
Sbjct: 771 ASSEGKSEMKKLRQQLE----------AAEKQIKHLEIEKNAESSKASSITRELQG---- 816
Query: 552 TLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTE 611
+ L++++ + NLS V+++K+T EK+ + L K A+ +E
Sbjct: 817 --------RELKLTNLQE------NLS---EVSQVKETLEKE-----LQILKEKFAEASE 854
Query: 612 ETEENLRS--SVINSIREIKEEIGNLKSS----HSGVLEIENSVDDLSSRMDILEERIDS 665
E RS +N + + +E+ L S + ++E + R + L + +
Sbjct: 855 EAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEK 914
Query: 666 LEDQIEEFSK----DTMQMTKQIIS-KERQRDIEE 695
LE+ I E K ++ Q+TK + ++RD+EE
Sbjct: 915 LENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEE 949
Score = 33.1 bits (74), Expect = 1.1
Identities = 39/208 (18%), Positives = 86/208 (41%), Gaps = 31/208 (14%)
Query: 579 ISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEEN-------LRSSVINSIREIKEE 631
++T K + E +K L +E+ A+L E N + S++ I ++E+
Sbjct: 492 VATVSEKSRIMELEKDLALRVQEV----AELRRRLESNKPAGDVDMSLSLLQEISSLQEK 547
Query: 632 IGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQR 691
+ ++ H EI + + +R + ++ I +L E+ SK+ + ++
Sbjct: 548 LEVTRTDHQR--EITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKL------- 598
Query: 692 DIEERSRSCNIRLIGIPEKESYENRAEDII---KEIIDENFAELKKGSSLEIVSACRVPS 748
E + N +I + ++++ E I ++ ++E KG E + +
Sbjct: 599 ---EHANKENSDVIAL-----WKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKT 650
Query: 749 KIDEKRLTPRHILVKFWNSSDKEKIIRA 776
+I++ RL +H + N D E+ A
Sbjct: 651 QIEKMRLDYQHEIENLQNQQDSERAAHA 678
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 70.5 bits (171), Expect = 6e-12
Identities = 114/444 (25%), Positives = 179/444 (40%), Gaps = 67/444 (15%)
Query: 118 KIEGENSKIGDDNENLTFKLEVNEL-SGKLDNTNEYNSN--------------DGKKLPQ 162
K E E K ++ L E EL +GK D + + S D +P
Sbjct: 235 KKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPA 294
Query: 163 GESRSYEVMGSMEETLCNIDDRDGNRNV-HLEFTERESRKDGEDEFVKEMREERKFQKLK 221
E ++ + ++ + +D + E E+E +K VK M+E KLK
Sbjct: 295 SEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA--LAKLK 352
Query: 222 NKEEVLKASREEKV--LMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCE 279
+EE K EE++ L + A L + KQ +E + + + E
Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQ--------KEKERKERLKKE 404
Query: 280 VKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGI-QEKRDK 338
KL K E + ++ +L+ +Q V KD LP+K I + ++ I Q+ K
Sbjct: 405 GKLLTKSQREARARAEA-TLKLLQAQGVEVPS--KDSLPKKRPIYEDKKRKKIPQQLESK 461
Query: 339 TLIDSKH--RAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMED 396
+ +S A E+ G+ K E +E +EEE +E LD+ + M
Sbjct: 462 EVSESMELCAAVEVMEQGVP---------EKEETPPPVEPEEEEDTEDAGLDDWEA-MAS 511
Query: 397 DEDTSGLE-------------EEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQD 443
DE+T +E EEEEE EE+EE E EE E+ G E +EE D
Sbjct: 512 DEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSD 571
Query: 444 STFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKAS 503
G TL D K E++SD + DS +D EE K+ +++ L K
Sbjct: 572 EKDSGKTL-DKKPSKEMSSD----SEYDSDDDRTKEERAYDKAKR--RIEKRRLEHSKNV 624
Query: 504 RRQK-EIPFSYLVG--DSGKKKLV 524
+K P ++G D+GK K++
Sbjct: 625 NTEKLRAPIICVLGHVDTGKTKIL 648
Score = 57.8 bits (138), Expect = 4e-08
Identities = 105/487 (21%), Positives = 186/487 (38%), Gaps = 72/487 (14%)
Query: 84 KATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNELS 143
K P+V+ S +F ++ A K K + + D+++ + + +N
Sbjct: 125 KTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSG 184
Query: 144 GKLDNTNEY-NSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTERESRKD 202
D ++E+ S G+K Q + E D + + ++ ++ +
Sbjct: 185 ESGDESDEFLQSRKGQKKNQKNKPGPNIESGNE---------DDDASFKIKTVAQKKAEK 235
Query: 203 GEDEFVKEMREERKFQKLKNKEEVLKASREE-----------------KVLMDEGAVLTL 245
E E K E+ K +KLK KEE+ +++ KV +D G +
Sbjct: 236 KERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVI--- 292
Query: 246 VADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIK-TFSDLQ-SLRKFA 303
A A + + N + +++ + K E K K G K T +Q +L K
Sbjct: 293 PASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLK 352
Query: 304 SQKSSVKELLKDVLPQKEEINQGGRKYG--IQEKRDKTLIDSKHRAGEITSDG-LSFLFL 360
++ K ++ + + EE+ ++ QEKR++ K R + +G L
Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQ 412
Query: 361 KEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDED--------------------- 399
+E + +K L+ Q E + L ++ ED +
Sbjct: 413 REARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAA 472
Query: 400 ----TSGLEEEEEEPSGLEEEEEE--EASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVD 453
G+ E+EE P +E EEEE E +GL++ EA +EE E+ + H V
Sbjct: 473 VEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGN----KVHIEVK 528
Query: 454 AKHEVEITSDGMETTFIDSVEDSESEEEEEGKS--SETGKVKTTSLTEKKASRRQKEIPF 511
E E + E + E+SE EEEEEG+S SE + EK + + + P
Sbjct: 529 ENPEEEEEEEEEE----EEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPS 584
Query: 512 SYLVGDS 518
+ DS
Sbjct: 585 KEMSSDS 591
Score = 42.0 bits (97), Expect = 0.002
Identities = 103/515 (20%), Positives = 196/515 (38%), Gaps = 79/515 (15%)
Query: 213 EERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDF 272
+E++ QK K K K ++K DE +L + +LS I V EN+
Sbjct: 33 KEQEPQKSKGK----KKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENN- 87
Query: 273 EPKFLCEVKLAFKCDGEIKTFSDLQSLR---KFASQKSSVKELLK-----------DVLP 318
E +F + K G+ ++F D S K + K + K ++ + LP
Sbjct: 88 EEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLP 147
Query: 319 QKEE--INQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLET 376
+K + + +K+ E+ + K R+ I S G S E ++ + KN +
Sbjct: 148 KKAKGKAQKSNKKWDGSEEDEDNSKKIKERS-RINSSGESGDESDEFLQSRKGQKKNQKN 206
Query: 377 QEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEE 436
+ E D++AS E++E E +EE+ + E++E ++++
Sbjct: 207 KPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQ 266
Query: 437 EQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTS 496
+ E F+ T+ K +V + + + + + + +E++ EG + K K
Sbjct: 267 SKQKESQRKFEEETV---KSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKG 323
Query: 497 LTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLA 556
E+K ++K G S + + K +EEEE +
Sbjct: 324 EKEEKEKEKKK--------GPSKATVKAMQEALAKLKEEEERQKREEE------------ 363
Query: 557 SPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEEN 616
K LE + K+ + +K E KK + +E KE L +++
Sbjct: 364 ERIKRLEELEAKRKEEER---------LEQEKRERKKQKEKERKERLKKEGKLLTKSQRE 414
Query: 617 LRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKD 676
R+ +++ ++ + GV E+ S D L + I E+ K
Sbjct: 415 ARARAEATLKLLQAQ---------GV-EVP-SKDSLPKKRPIYED-------------KK 450
Query: 677 TMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKE 711
++ +Q+ SKE + E + + G+PEKE
Sbjct: 451 RKKIPQQLESKEVSESM-ELCAAVEVMEQGVPEKE 484
Score = 40.0 bits (92), Expect = 0.009
Identities = 93/469 (19%), Positives = 172/469 (36%), Gaps = 65/469 (13%)
Query: 371 MKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEAS 430
M + + E S +++D +A E + + E+E ++ G +++E+++ E+D
Sbjct: 1 MGKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILK 60
Query: 431 GLEE---------EEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEE 481
LEE + +T T +K + + G + +F D+ DSE E+
Sbjct: 61 ELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDN--DSEELED 118
Query: 482 EEGKSSETGKVKT------------TSLTEKKASRRQK---------------------- 507
++ KS +T K K L +K + QK
Sbjct: 119 KDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERS 178
Query: 508 EIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHD 567
I S GD + L + K Q+ + S K E
Sbjct: 179 RINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKER 238
Query: 568 EHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVI--NSI 625
E KK KL+K +EK+ ++ + ++ + EE ++S V +
Sbjct: 239 ERKKRDEEK-------AKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGV 291
Query: 626 REIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQII 685
EE ++ E + D + EE+ +++ + SK T++ ++ +
Sbjct: 292 IPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEK---EKEKKKGPSKATVKAMQEAL 348
Query: 686 SK-----ERQ-RDIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDENFAELKKGSSLE 739
+K ERQ R+ EER + E+E E + K+ E LKK L
Sbjct: 349 AKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLL 408
Query: 740 IVS--ACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRERREITYQ 786
S R ++ K L + + V +S K++ I ++R++I Q
Sbjct: 409 TKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQ 457
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 66.6 bits (161), Expect = 9e-11
Identities = 135/725 (18%), Positives = 291/725 (40%), Gaps = 90/725 (12%)
Query: 18 KKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLME------IQDLMF---EE 68
KK+N ++ L E++K + L K++ + + K L+ +Q+ M+ EE
Sbjct: 224 KKKNAELQEKLPLAESEKS---EIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 280
Query: 69 MRETLKNDLKA---VLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSK 125
+RE K K + + + E + ++Q L Q+ ++ + +
Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEK----ELREQEKE 336
Query: 126 IGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEV---MGSMEETLCNID 182
+ + E + ++ E K+ E +K+ + E R +E M E+ + + +
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Query: 183 DRDGNRNVHL-EFTERESRKDGEDEFVKEMREERKFQKL--KNKEEVLKASREEKVLMDE 239
+R ++ L E ER ++ E V++MREE+K Q+ K +++ K EE++ E
Sbjct: 397 ERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRERE 456
Query: 240 GAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSL 299
+ + + KQ N++ E +++ + L E K L
Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWE-QEEKEWQQQRLPEQK------------EKLWEQ 503
Query: 300 RKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLF 359
K Q+ + E + + Q+E Q + + ++ R++ D E D
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE--DQMWEQEEKMRD------ 555
Query: 360 LKEVKVAKPEEMKNLETQEEE---------FSELEELDEEASGMEDDEDTSGLEEE--EE 408
+E K+ EE +TQE+E E E + E M ++E+ +EE +E
Sbjct: 556 -QEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 409 EPSGLEEEEE---EEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGM 465
+ ++E+EE E+ ++E E E+EE+ +++ ++ L + K ++
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL------- 667
Query: 466 ETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVK 525
+ +++ E +E+E K E K++ + ++K + Q+++ + + KK +
Sbjct: 668 --WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREE 725
Query: 526 HQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTK 585
+++ + +E+ + Q + EM E K
Sbjct: 726 EEMMREQEEKMQEQEEKMQ--------------EQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Query: 586 LKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEI 645
+K + +H + +E ++ + + EE +R +++ + ++ +
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE----EKMRGQEEKMRGQEEKMWGQ 827
Query: 646 ENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLI 705
E + +M EE++ E+++EE K Q K +E+ R EE+ R ++
Sbjct: 828 EEKMWGQEEKMWGQEEKMWGQEEKMEE--KMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Query: 706 GIPEK 710
G EK
Sbjct: 886 GQEEK 890
Score = 37.0 bits (84), Expect = 0.079
Identities = 67/346 (19%), Positives = 139/346 (40%), Gaps = 26/346 (7%)
Query: 111 QKTGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEV 170
Q+ M K + + K D E + + + E K+ E +K+ + E + E
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 622
Query: 171 MGSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKAS 230
M E + +++ E + K E + + E +E K + + +E K
Sbjct: 623 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKE--KLWEHEKMQEQEKMQ 680
Query: 231 REEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEI 290
+E+ + ++ + + T D K +RE E K E ++ + + ++
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE--ESMRER--EKKMREEEEMMREQEEKM 736
Query: 291 KTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEI 350
+ + K Q+ + E + + Q+E++ + R + E+++K K + E
Sbjct: 737 Q-----EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR---LPEQKEKLWEHEKMQEQEK 788
Query: 351 TSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEEL----DEEASGMED-----DEDTS 401
+ + +E K+ EE + QEE+ EE +E+ G E+ +E
Sbjct: 789 IWEQEEKMRDQEEKMRGQEE--KMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMW 846
Query: 402 GLEEE-EEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTF 446
G EE+ EE+ G EE+ E+ + E E+EE+ +++ +
Sbjct: 847 GQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIY 892
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 66.2 bits (160), Expect = 1e-10
Identities = 122/640 (19%), Positives = 261/640 (40%), Gaps = 90/640 (14%)
Query: 195 TERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLM-----DEGAVLTLVADL 249
+E+E+ ++ DE ++E+ E+ K + K +++ R+ K L+ D+G V+
Sbjct: 314 SEKEALQEQLDERLQEL-EKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQ 372
Query: 250 SSATLDISKQW-SNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSS 308
TL++ ++ + + + +++ + + L E K E F +L+ A +
Sbjct: 373 MHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEK----SERAAFEELEKALSTAQKTEE 428
Query: 309 VKELLKDVLPQKE---EINQGGRKYGIQEKRDKT---LIDSKHRAGEITSDGLSFLFLKE 362
+ LK + ++ E + +Q++ + ++D ++ E L L KE
Sbjct: 429 ARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKE 488
Query: 363 VKVAKPEEMKNLETQEEEFSELEELDEEASGME--------DDEDTSGLEEEEEEPSGLE 414
+ + E K L+T+E EF E ++ E S E + +++ LEE E + +
Sbjct: 489 LARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAIL 548
Query: 415 EEEEEEASGLEEDEA----------SGLEEEEEQTSEQDSTFQGHTLVDA-KHEVEIT-- 461
E E + L+++ S LE+ ++ Q H + KH EIT
Sbjct: 549 TESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVM 608
Query: 462 --SDGMETTFIDSVEDSESEEE----EEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLV 515
E + +D+ E+ ++ +E K++ EK+ + KEI F +
Sbjct: 609 VEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHI 668
Query: 516 GDSGKKKLVKHQVVHKTQEE---EETAVPTSQGTGTPCLTLCLASPSK---SLEMSHDEH 569
+ +K L K V E E + V ++ L++ K LE DE
Sbjct: 669 EEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQ 728
Query: 570 KKHSHTNLS--ISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIRE 627
K H + I +++TE+ ++ EL KE D +
Sbjct: 729 KNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERD-----------------KH 771
Query: 628 IKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISK 687
+KE ++++ + + E + S+++D+ + + +Q + + + Q+ ++++
Sbjct: 772 LKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDL 831
Query: 688 ERQR--------DIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDENFAELKKGSSLE 739
E +R ++E + + E ++++ + +D+++++ +N +K SL
Sbjct: 832 ETERILLTKQVAEVEAQKKDV------CTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLT 885
Query: 740 IVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRE 779
V ++ E+ T + ILV +KE +I RE
Sbjct: 886 QVYESKLEDGNKEQEQT-KQILV------EKENMILQMRE 918
Score = 56.6 bits (135), Expect = 1e-07
Identities = 152/796 (19%), Positives = 334/796 (41%), Gaps = 84/796 (10%)
Query: 7 SVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMF 66
S+Q + +R+ K+E + MK+ +++ IA + L K+++ + ++ ++
Sbjct: 454 SLQQELSRV--KQEVVDVMKKS----SEEQIAKLQKLHEKELARKEQELTKKLQTRE--- 504
Query: 67 EEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKI 126
E +E +K L+ I + K + S + E L LQK ++ E EN
Sbjct: 505 REFQEQMKVALEKSQSEYLKISQEKEQQESLALEE------LELQKKAIL--TESENKLR 556
Query: 127 GDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKL-----PQGESRSYEVMGSMEETLCNI 181
E T++ + EL L+ + + N N K L + + E+ +E+ +
Sbjct: 557 DLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTEL 616
Query: 182 DDRDGNRNVHLEFTER----ESRKDGEDEFVKEMREERKFQKLKNKEEVLKASRE---EK 234
+ ++ +TE+ + + E E ++E E+ K LK+KE + +A E EK
Sbjct: 617 ESLKHQQDA--LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEK 674
Query: 235 VLMDEGAVLTLVADLSSATLDISK---QWSNVFNILRENDFEPKFLCEVKLAFKCDGEIK 291
L T + LSS ++ K + ++L++ + K E K+ + + +
Sbjct: 675 TLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ 734
Query: 292 TFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKY--GIQEKRDKTLIDSKHRAGE 349
+ + + Q++ ++ LKD + Q E + + K+ Q + D K GE
Sbjct: 735 QVDSIIKEHEVSIQRT--EKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 792
Query: 350 ITSDGLSFLFLKEVKVAKPEEMKNLETQ----EEEFSELEE----LDEEASGMEDDED-- 399
+ + + A E+ K E Q +++ +LE L ++ + +E +
Sbjct: 793 LQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDV 852
Query: 400 TSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLE----EEEEQTSEQDSTFQGHTLVDAK 455
+ L+ + + L ++ E++ S +E+ S + + E+ EQ+ T Q LV+ +
Sbjct: 853 CTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQ--ILVEKE 910
Query: 456 HEVEITSDGME------TTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEI 509
+ + +G + T + + EDS EE ++ + K ++KA Q+ +
Sbjct: 911 NMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETL 970
Query: 510 PFSYLVGDSGKKKLVKHQVVHKTQEEE-------ETAVPTSQGTGTPCLTLCLASPSKSL 562
L ++ KK +++ + +Q+E+ E A S G + ++ + + +
Sbjct: 971 KKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGI-SDAVSRLETNQKEQI 1029
Query: 563 EMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENL----- 617
E + H++ N IS KL + E+ + +H +L KE ++ E ++ L
Sbjct: 1030 ESLTEVHRR--ELNDVISIWEKKLNQQAEEL-QEIHEIQLQEKEQEVAELKQKILLFGCE 1086
Query: 618 RSSVINSIREIKEE----IGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEF 673
+ + I +KEE L + + V+ L+ L+ ++ LE + +
Sbjct: 1087 KEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKS 1146
Query: 674 SKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKE--SYENRAEDIIKEIIDEN--F 729
K+ + +Q++ + + ++R S + ++E S ++ E K + D++ F
Sbjct: 1147 LKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEF 1206
Query: 730 AELKKGSSLEIVSACR 745
+L + ++++ C+
Sbjct: 1207 KKLSEELAIQLDICCK 1222
Score = 50.8 bits (120), Expect = 5e-06
Identities = 132/740 (17%), Positives = 299/740 (40%), Gaps = 155/740 (20%)
Query: 68 EMRETLKNDLKAVLGGKATIPEVKNSENSSSR------TEFQQIINLALQKTGMVG---K 118
++++ L ++ AV K + E K +S S+ + Q I+L+ ++ + +
Sbjct: 1343 QLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQ 1402
Query: 119 IEGENSKIGDDNENLTFKLEV--NELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEE 176
+ E ++ D ++L+FK++ E L+ +++++ + + +SR + +++E
Sbjct: 1403 YDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKE 1462
Query: 177 TLCNIDDRDGNRNVHLEFTERES-RKDGEDEFVKEM--REERKFQKLKNKEEVLKASREE 233
+ LE +E+ KD + +KE ++ ++F LK + E K+ E+
Sbjct: 1463 L-----------QIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEK 1511
Query: 234 KVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTF 293
K S+ ++ Q + + + E+ K + EI++
Sbjct: 1512 KE--------------SNLETELKSQTARIMEL--EDHITQKTI-----------EIESL 1544
Query: 294 SDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSD 353
+++ L+ + QK + L L +E+ E++D + +++ + +T +
Sbjct: 1545 NEV--LKNYNQQKDIEHKELVQKLQHFQELG---------EEKDNRVKEAEEKI--LTLE 1591
Query: 354 GLSFLFLKEVKVAKPE-EMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSG 412
+ E++ K E E NL + +E EE +ED ++ + E
Sbjct: 1592 NQVYSMKAELETKKKELEHVNLSVKSKE--------EELKALEDRLESESAAKLAE---- 1639
Query: 413 LEEEEEEEASGLEEDEASGLEEEEEQ---TSEQDSTFQGHTLVDAKHEVEITSDGMETTF 469
L+ + E++ + +++ S +EE+EEQ +E + L + + EV I + ++
Sbjct: 1640 LKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLK--- 1696
Query: 470 IDSVEDSESE---------------EEEEGKS--------SETGKVKTTSLTEKK----- 501
SVE S+SE E+EE S E V +LTEK+
Sbjct: 1697 --SVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQR 1754
Query: 502 -ASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSK 560
+++ + + + +++L+K + Q E+++ + Q L +
Sbjct: 1755 VGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQE------ELEEKNKKY 1808
Query: 561 SLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSS 620
SL ++ K+ N+ L+ + +TL +ELT + E+ + L S
Sbjct: 1809 SLIVAQHVEKEGGKNNIQAK---QNLENVFDDVQKTLQEKELT---CQILEQKIKELDSC 1862
Query: 621 VINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERID---------------- 664
++ + E+ L S + L+ +D + ++LEE +
Sbjct: 1863 LVRQKEVHRVEMEELTSKYE-KLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNM 1921
Query: 665 -----SLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAED 719
LE ++ ++ ++ K+I+ ++ + + + ++ K+ Y+ E+
Sbjct: 1922 EAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEIL----KKEYDQEREE 1977
Query: 720 IIKEIIDENFAELKKGSSLE 739
IK+ ++ ELK S+L+
Sbjct: 1978 KIKQ--EQEDLELKHNSTLK 1995
Score = 49.7 bits (117), Expect = 1e-05
Identities = 172/846 (20%), Positives = 336/846 (39%), Gaps = 151/846 (17%)
Query: 14 RLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETL 73
+LA+ ++ + ++ E++ T K +A V + + KDV ++ K+ ++QDLM + ++
Sbjct: 820 QLAQLQQKLLDLETERILLT-KQVAEV-EAQKKDVCTELDAHKI--QVQDLMQQLEKQNS 875
Query: 74 KNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKI-EGENSKIGDDNEN 132
+ + K ++ +V S+ E +Q + ++K M+ ++ EG+ +I E
Sbjct: 876 EMEQKV-----KSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEI----EI 926
Query: 133 LTFKLEVNELSGKLDNTNEYNS---NDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRN 189
LT KL E S + N EY + N KK+ + + ++ E+ ++++ L D++
Sbjct: 927 LTQKLSAKEDSIHILN-EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLL---DQEAKLK 982
Query: 190 VHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADL 249
LE T E + E +F +M E + + V + +K ++ + ++
Sbjct: 983 KELENTALELSQK-EKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIES------LTEV 1035
Query: 250 SSATL-DISKQWSNVFNI------------LRENDFEPKFLCEVKLAFKCDGE------- 289
L D+ W N L+E + E L + L F C+ E
Sbjct: 1036 HRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEIT 1095
Query: 290 ------IKTFSDLQSLRKFASQKSS-VKELLKDVLPQKEEINQGGRKYGIQEKRDKTLID 342
+K + L L++ QKS+ V L +D K + EK + L
Sbjct: 1096 WLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHL----------EKLEVDLNK 1145
Query: 343 SKHRAGEITSDGLSFLFLKEVKVAKPEEMKN-LETQEEEFSELEELDEEASGMEDDEDTS 401
S + + L E K E+ + L+T +EEF L+ E+++ +D+
Sbjct: 1146 SLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLE 1205
Query: 402 GLEEEEE----------EPSGLEEEEEEEASGLEEDEA---------------------- 429
+ EE + L E + E + +
Sbjct: 1206 FKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALL 1265
Query: 430 ------SGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDS---VEDSESEE 480
S LE + Q +E+ +T + A H++E + +++ D V + E+ +
Sbjct: 1266 IKTCTVSELEAQLRQLTEEQNTLN-ISFQQATHQLEEKENQIKSMKADIESLVTEKEALQ 1324
Query: 481 EEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHK--------- 531
+E G + K + +T+ K + I L+ + K+K V+ + K
Sbjct: 1325 KEGGNQQQAASEKESCITQLK-KELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQL 1383
Query: 532 ----TQEEEETAVPT--SQGTGTPC--------LTLCLASPSK----SLEMSHDEHKKHS 573
+ E+E A+ + Q C L+ + + SK +LE D K S
Sbjct: 1384 QNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFS 1443
Query: 574 HTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIG 633
+ T+ + T ++ L EL SKEA +E L+ + + G
Sbjct: 1444 EWKKKAQSRFTQHQNTVKELQIQL---ELKSKEAYEKDEQINLLKEELDQQNKRFDCLKG 1500
Query: 634 NLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDI 693
++ S ++E +L + + RI LED I + + + + + + + +Q+DI
Sbjct: 1501 EMEDDKS---KMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDI 1557
Query: 694 EER---SRSCNIRLIGIPEKESYENRAEDIIKEIIDENF---AELK-KGSSLEIVSACRV 746
E + + + + +G EK++ AE+ I + ++ + AEL+ K LE V+ V
Sbjct: 1558 EHKELVQKLQHFQELG-EEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVN-LSV 1615
Query: 747 PSKIDE 752
SK +E
Sbjct: 1616 KSKEEE 1621
Score = 30.0 bits (66), Expect = 9.6
Identities = 52/231 (22%), Positives = 95/231 (41%), Gaps = 20/231 (8%)
Query: 268 RENDFEPKFLCEVKLAFKCDGEI-KTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQG 326
+ ND E K + K EI + DL+ LRK Q+ E+LK Q+ E
Sbjct: 1924 QHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQEL---EILKKEYDQEREEKIK 1980
Query: 327 GRKYGIQEKRDKTLIDSKHRAGEITSD------GLSFLFLKEVKVAKPEEMKNLETQEEE 380
+ ++ K + TL K E + L + + A+ E + LE+ +EE
Sbjct: 1981 QEQEDLELKHNSTL---KQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEE 2037
Query: 381 FSELEELDEEASGMEDDEDTSGLEEE-----EEEPSGLEEEEEEEASGLEEDEASGLEEE 435
++L L + A +D + T+ EE EEE + + + + L++ LE+E
Sbjct: 2038 TNQL--LKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQE 2095
Query: 436 EEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKS 486
E ++ + + T + K + S E F + + + E ++ K+
Sbjct: 2096 ENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKN 2146
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 65.9 bits (159), Expect = 2e-10
Identities = 149/786 (18%), Positives = 309/786 (39%), Gaps = 162/786 (20%)
Query: 18 KKENITYMKREQL------------TETDKDIAPVLDLKCKDVSAIMNKFK-VLMEIQDL 64
K+E I +K +Q+ TETDK+ A V KFK L+ ++ +
Sbjct: 248 KREVIDLLKPDQVEGIQKSGTKKLKTETDKENAEV-------------KFKDFLLSLKTM 294
Query: 65 MFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENS 124
MF E DL G ++++ SS+ E +I+ +K ++ ++ + +
Sbjct: 295 MFSEDEALCVVDLLKEKSGV-----IQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAA 349
Query: 125 KIGDDNENLTFKL------------EVNELSGKLDNTNEYNSN----DGKKLPQGESRSY 168
D + LT ++ + + G L+ + N ++ Q + +
Sbjct: 350 ATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQ 409
Query: 169 EVMGSMEETLCNIDDRDGNRNVHLEFT--ERESRKDGEDEFVKEMREE--RKFQKLKNKE 224
+V ME + ++ +G + T + ES++ E + ++R++ R +L K
Sbjct: 410 QVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAE---LNKLRQDYARLVNELTEKT 466
Query: 225 EVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILR---------ENDFEPK 275
L+ +K ++ A L + ++W V + +R + D + K
Sbjct: 467 GKLQQEEVQKKNAEQAAT-----QLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSK 521
Query: 276 FLCEVK------------LAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEI 323
F+ + L K E + ++S +K +++ S++ ++D+L Q E +
Sbjct: 522 FVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEAL 581
Query: 324 NQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSE 383
+++ Q I ++ A + + L +V K +++K +T++ SE
Sbjct: 582 KAQIQQFHSQ-------IAAQTSASVLAEE------LHKVIAEKDKQIK--QTEDSLASE 626
Query: 384 LEELDEEASGMEDDEDTSGLEEEE---------EEPSGLEEEEEEEASGLEEDEASGLEE 434
+ L + ++D ++ + L + E E+ + E E+ + S +D+ L E
Sbjct: 627 RDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLE 686
Query: 435 EEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKT 494
E+ Q + + L D ++ ++T + E+ E+ + K+KT
Sbjct: 687 EQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKT 746
Query: 495 TSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVH-KTQEEEETAVPTSQGTGTPCLTL 553
++L++ ++ T+EEE A+ T
Sbjct: 747 V-------------------------EELLETGLIQVATKEEELNAIRTE---------- 771
Query: 554 CLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKT-EEKKHRTLHTEELTSKEADLTEE 612
+ SL + K + +S ++ V +LKK EK + EEL E L
Sbjct: 772 -----NSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAEL-LKVA 825
Query: 613 TEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEE 672
+E + I+ +KEEIGN++ + L I + V +L + + EE++++++ +EE
Sbjct: 826 NKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEE 885
Query: 673 FSKDTMQMTKQI-------------ISKERQRDIEERSRSCNIRLIGI--PEKESYENRA 717
KD K + + + Q +++E S + + I EKE+ R
Sbjct: 886 KEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRL 945
Query: 718 EDIIKE 723
E ++KE
Sbjct: 946 EAMLKE 951
Score = 46.2 bits (108), Expect = 1e-04
Identities = 109/595 (18%), Positives = 239/595 (40%), Gaps = 76/595 (12%)
Query: 1 MSDVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKD-----VSAIMNKF 55
+ V +++ ++A K+E + ++ E + T + V DLK K ++++ +
Sbjct: 744 LKTVEELLETGLIQVATKEEELNAIRTENSSLTKE----VQDLKAKQNDQVSFASLVEEL 799
Query: 56 KVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGM 115
K ++ +D + + E L+ +L V + T+ ++K E + + E + Q+ +
Sbjct: 800 KKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQ-EIKALKEEIGNVQLEKAQQLSI 858
Query: 116 VGKI-EGENSKIGDDNENLTFKLEVNELSGKLDNTNEY-----NSNDGKK-----LPQGE 164
K+ E +N G + + T K + E L NT ++ N+ K + Q
Sbjct: 859 TSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHN 918
Query: 165 SRSYEVMGSMEETLCNIDDRDGN-RNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNK 223
+ EE + +++ + + ERES + + ++++++E K K++
Sbjct: 919 LKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKL--FKSQ 976
Query: 224 EEVLKASREE------------KVLMDEGAVLTLVADLSSATLDISKQWSNVFNILREND 271
E LK + KV+ + ++ + + + D + N LRE +
Sbjct: 977 IEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKN 1036
Query: 272 FEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQ---KEEINQGGR 328
+E D KT + Q ++ + + KE+LK + P+ ++ G
Sbjct: 1037 WEAMEALASTEKMLQDKVNKTSKERQ--QQVEAVELEAKEVLKKLFPKVSVPSNLSYGEW 1094
Query: 329 KYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNL-----ETQEEEFSE 383
+G ++K + + AG S+ + L E K+ + +EM L E + +E
Sbjct: 1095 LHGFEKKAKECM------AGTSGSEEVKVL---EHKLKEADEMHTLLQLECEKYKSVLAE 1145
Query: 384 LE----------ELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLE 433
E E +E ++ DE +++ + + E+E E S ++ E E
Sbjct: 1146 TEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRE 1205
Query: 434 EEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEE----EGKSSET 489
E + + + + T V E++ ++ DS ++ + EE + + +ET
Sbjct: 1206 REHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNET 1265
Query: 490 -GKVKTTSLTEKKA------SRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEE 537
K++T +K +++ E+ S +V +G ++++ V E E
Sbjct: 1266 LTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSE 1320
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 65.9 bits (159), Expect = 2e-10
Identities = 149/786 (18%), Positives = 309/786 (39%), Gaps = 162/786 (20%)
Query: 18 KKENITYMKREQL------------TETDKDIAPVLDLKCKDVSAIMNKFK-VLMEIQDL 64
K+E I +K +Q+ TETDK+ A V KFK L+ ++ +
Sbjct: 248 KREVIDLLKPDQVEGIQKSGTKKLKTETDKENAEV-------------KFKDFLLSLKTM 294
Query: 65 MFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENS 124
MF E DL G ++++ SS+ E +I+ +K ++ ++ + +
Sbjct: 295 MFSEDEALCVVDLLKEKSGV-----IQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAA 349
Query: 125 KIGDDNENLTFKL------------EVNELSGKLDNTNEYNSN----DGKKLPQGESRSY 168
D + LT ++ + + G L+ + N ++ Q + +
Sbjct: 350 ATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQ 409
Query: 169 EVMGSMEETLCNIDDRDGNRNVHLEFT--ERESRKDGEDEFVKEMREE--RKFQKLKNKE 224
+V ME + ++ +G + T + ES++ E + ++R++ R +L K
Sbjct: 410 QVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAE---LNKLRQDYARLVNELTEKT 466
Query: 225 EVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILR---------ENDFEPK 275
L+ +K ++ A L + ++W V + +R + D + K
Sbjct: 467 GKLQQEEVQKKNAEQAAT-----QLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSK 521
Query: 276 FLCEVK------------LAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEI 323
F+ + L K E + ++S +K +++ S++ ++D+L Q E +
Sbjct: 522 FVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEAL 581
Query: 324 NQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSE 383
+++ Q I ++ A + + L +V K +++K +T++ SE
Sbjct: 582 KAQIQQFHSQ-------IAAQTSASVLAEE------LHKVIAEKDKQIK--QTEDSLASE 626
Query: 384 LEELDEEASGMEDDEDTSGLEEEE---------EEPSGLEEEEEEEASGLEEDEASGLEE 434
+ L + ++D ++ + L + E E+ + E E+ + S +D+ L E
Sbjct: 627 RDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLE 686
Query: 435 EEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKT 494
E+ Q + + L D ++ ++T + E+ E+ + K+KT
Sbjct: 687 EQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKT 746
Query: 495 TSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVH-KTQEEEETAVPTSQGTGTPCLTL 553
++L++ ++ T+EEE A+ T
Sbjct: 747 V-------------------------EELLETGLIQVATKEEELNAIRTE---------- 771
Query: 554 CLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKT-EEKKHRTLHTEELTSKEADLTEE 612
+ SL + K + +S ++ V +LKK EK + EEL E L
Sbjct: 772 -----NSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAEL-LKVA 825
Query: 613 TEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEE 672
+E + I+ +KEEIGN++ + L I + V +L + + EE++++++ +EE
Sbjct: 826 NKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEE 885
Query: 673 FSKDTMQMTKQI-------------ISKERQRDIEERSRSCNIRLIGI--PEKESYENRA 717
KD K + + + Q +++E S + + I EKE+ R
Sbjct: 886 KEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRL 945
Query: 718 EDIIKE 723
E ++KE
Sbjct: 946 EAMLKE 951
Score = 62.8 bits (151), Expect = 1e-09
Identities = 139/731 (19%), Positives = 290/731 (39%), Gaps = 97/731 (13%)
Query: 16 AKKKENITYMKREQLTETDKDIAPVLDLKC------KDVSAIMNKFKV-LMEIQDLM--F 66
A K+ + +E +TE ++ + +K K+ + NK V E Q + F
Sbjct: 349 AATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKF 408
Query: 67 EEMRETLKNDLK-----------AVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGM 115
+++RE ++ ++ AV + +++E + R ++ +++N +KTG
Sbjct: 409 QQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGK 468
Query: 116 VGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSME 175
+ + E + K + K+++ E + + Y K+ + E+ ++
Sbjct: 469 LQQEEVQ--KKNAEQAATQLKVQLQEAERRWEEVQSYIR---KRTAEHEAAQQDLQSKF- 522
Query: 176 ETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKV 235
+ + +++H + T+ K ++ + ++ E QK NKEE L+ ++ +
Sbjct: 523 -----VAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE--QKRVNKEESLQMQVQDIL 575
Query: 236 LMDEGAVLTLVADLSSATLDISKQWS------NVFNILRENDFEPKFLCEVKLAFKCDG- 288
+E L A + I+ Q S + ++ E D + K E LA + D
Sbjct: 576 EQNEA----LKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIK-QTEDSLASERDRL 630
Query: 289 -----EIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDS 343
E+K ++ L K QK ++ L + E+ + + + K DK +
Sbjct: 631 TSKEEELKDIQNMNFLLKAEVQK--LQALANEQAAAAHELEK--MQQSVYVKDDKIRLLE 686
Query: 344 KHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDE-EASGMEDDEDTSG 402
+ EI++ F L + A E++ L+T E + +++ E E DE
Sbjct: 687 EQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKT 746
Query: 403 LEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITS 462
+EE E +EEE + + + +S +E ++ ++Q+ +LV+ +V
Sbjct: 747 VEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEK 806
Query: 463 DGMETTFIDSVED----------------SESEEEEEGKSSETGKVKTTSLTEKKASRRQ 506
DG I SVE+ + ++E + E G V+ + + +
Sbjct: 807 DGK----IKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKV 862
Query: 507 KEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSH 566
+E+ + L G + +K + K ++ T L ++SL+
Sbjct: 863 QELQ-NLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQD----------LQEENESLKAHV 911
Query: 567 DEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEE--LTSKEADLTEETEENLRSSVINS 624
E +H+ S ++ +L+ ++K L E L +E+DL+ +T+ L V +
Sbjct: 912 QEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQ--LLQDVQDE 969
Query: 625 IREIKEEIGNLK-------SSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDT 677
+ K +I LK SS E+ + + + L +DSL+D +E K
Sbjct: 970 NKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKN 1029
Query: 678 MQMTKQIISKE 688
+ +Q+ + E
Sbjct: 1030 NERQQQVEAVE 1040
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 65.9 bits (159), Expect = 2e-10
Identities = 149/786 (18%), Positives = 309/786 (39%), Gaps = 162/786 (20%)
Query: 18 KKENITYMKREQL------------TETDKDIAPVLDLKCKDVSAIMNKFK-VLMEIQDL 64
K+E I +K +Q+ TETDK+ A V KFK L+ ++ +
Sbjct: 248 KREVIDLLKPDQVEGIQKSGTKKLKTETDKENAEV-------------KFKDFLLSLKTM 294
Query: 65 MFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENS 124
MF E DL G ++++ SS+ E +I+ +K ++ ++ + +
Sbjct: 295 MFSEDEALCVVDLLKEKSGV-----IQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAA 349
Query: 125 KIGDDNENLTFKL------------EVNELSGKLDNTNEYNSN----DGKKLPQGESRSY 168
D + LT ++ + + G L+ + N ++ Q + +
Sbjct: 350 ATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQ 409
Query: 169 EVMGSMEETLCNIDDRDGNRNVHLEFT--ERESRKDGEDEFVKEMREE--RKFQKLKNKE 224
+V ME + ++ +G + T + ES++ E + ++R++ R +L K
Sbjct: 410 QVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAE---LNKLRQDYARLVNELTEKT 466
Query: 225 EVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILR---------ENDFEPK 275
L+ +K ++ A L + ++W V + +R + D + K
Sbjct: 467 GKLQQEEVQKKNAEQAAT-----QLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSK 521
Query: 276 FLCEVK------------LAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEI 323
F+ + L K E + ++S +K +++ S++ ++D+L Q E +
Sbjct: 522 FVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEAL 581
Query: 324 NQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSE 383
+++ Q I ++ A + + L +V K +++K +T++ SE
Sbjct: 582 KAQIQQFHSQ-------IAAQTSASVLAEE------LHKVIAEKDKQIK--QTEDSLASE 626
Query: 384 LEELDEEASGMEDDEDTSGLEEEE---------EEPSGLEEEEEEEASGLEEDEASGLEE 434
+ L + ++D ++ + L + E E+ + E E+ + S +D+ L E
Sbjct: 627 RDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLE 686
Query: 435 EEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKT 494
E+ Q + + L D ++ ++T + E+ E+ + K+KT
Sbjct: 687 EQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKT 746
Query: 495 TSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVH-KTQEEEETAVPTSQGTGTPCLTL 553
++L++ ++ T+EEE A+ T
Sbjct: 747 V-------------------------EELLETGLIQVATKEEELNAIRTE---------- 771
Query: 554 CLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKT-EEKKHRTLHTEELTSKEADLTEE 612
+ SL + K + +S ++ V +LKK EK + EEL E L
Sbjct: 772 -----NSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAEL-LKVA 825
Query: 613 TEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEE 672
+E + I+ +KEEIGN++ + L I + V +L + + EE++++++ +EE
Sbjct: 826 NKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEE 885
Query: 673 FSKDTMQMTKQI-------------ISKERQRDIEERSRSCNIRLIGI--PEKESYENRA 717
KD K + + + Q +++E S + + I EKE+ R
Sbjct: 886 KEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRL 945
Query: 718 EDIIKE 723
E ++KE
Sbjct: 946 EAMLKE 951
Score = 46.2 bits (108), Expect = 1e-04
Identities = 109/595 (18%), Positives = 239/595 (40%), Gaps = 76/595 (12%)
Query: 1 MSDVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKD-----VSAIMNKF 55
+ V +++ ++A K+E + ++ E + T + V DLK K ++++ +
Sbjct: 744 LKTVEELLETGLIQVATKEEELNAIRTENSSLTKE----VQDLKAKQNDQVSFASLVEEL 799
Query: 56 KVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGM 115
K ++ +D + + E L+ +L V + T+ ++K E + + E + Q+ +
Sbjct: 800 KKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQ-EIKALKEEIGNVQLEKAQQLSI 858
Query: 116 VGKI-EGENSKIGDDNENLTFKLEVNELSGKLDNTNEY-----NSNDGKK-----LPQGE 164
K+ E +N G + + T K + E L NT ++ N+ K + Q
Sbjct: 859 TSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHN 918
Query: 165 SRSYEVMGSMEETLCNIDDRDGN-RNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNK 223
+ EE + +++ + + ERES + + ++++++E K K++
Sbjct: 919 LKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKL--FKSQ 976
Query: 224 EEVLKASREE------------KVLMDEGAVLTLVADLSSATLDISKQWSNVFNILREND 271
E LK + KV+ + ++ + + + D + N LRE +
Sbjct: 977 IEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKN 1036
Query: 272 FEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQ---KEEINQGGR 328
+E D KT + Q ++ + + KE+LK + P+ ++ G
Sbjct: 1037 WEAMEALASTEKMLQDKVNKTSKERQ--QQVEAVELEAKEVLKKLFPKVSVPSNLSYGEW 1094
Query: 329 KYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNL-----ETQEEEFSE 383
+G ++K + + AG S+ + L E K+ + +EM L E + +E
Sbjct: 1095 LHGFEKKAKECM------AGTSGSEEVKVL---EHKLKEADEMHTLLQLECEKYKSVLAE 1145
Query: 384 LE----------ELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLE 433
E E +E ++ DE +++ + + E+E E S ++ E E
Sbjct: 1146 TEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRE 1205
Query: 434 EEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEE----EGKSSET 489
E + + + + T V E++ ++ DS ++ + EE + + +ET
Sbjct: 1206 REHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNET 1265
Query: 490 -GKVKTTSLTEKKA------SRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEE 537
K++T +K +++ E+ S +V +G ++++ V E E
Sbjct: 1266 LTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSE 1320
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 65.5 bits (158), Expect = 2e-10
Identities = 118/579 (20%), Positives = 230/579 (39%), Gaps = 108/579 (18%)
Query: 152 YNSNDGKKLPQGESR--------SYEVMGSMEETLCNIDDRDGNRNVHLEFTERES---- 199
Y S K +GE+R S++ G +E+ L + + + ++E +E
Sbjct: 208 YYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALS 267
Query: 200 ----RKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLD 255
R DE +KE K KL+ K +++++ + E L V L L A L
Sbjct: 268 LELYRNTITDEELKE-----KNAKLQEKLQLVESEKSEIQLN----VKELKRKLERAKLL 318
Query: 256 ISKQWSNVFNILRENDFEPKFLCEVKLAFKC---DGEIKTFSDLQSLRKFASQKSSVKEL 312
+ +Q + E D K L V + + E+ + Q K Q+ ++E
Sbjct: 319 LPQQ-----QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW 373
Query: 313 LKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMK 372
+ + Q+E+I + K QE++ + + E ++ KE K+ + EEM
Sbjct: 374 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM- 432
Query: 373 NLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGL 432
+ +EE+ ELEE E + + E+ +EEE+ E+ +E+EA ++E +
Sbjct: 433 -MWEKEEKIRELEEKMHEQEKIREQEEK---RQEEEKIREQEKRQEQEAKMWRQEEK--I 486
Query: 433 EEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKV 492
E+EE+ EQ+ + HE E + + E +E+E + K+
Sbjct: 487 REQEEKIREQEEKMWRQE--EKIHEQE------------KIREEEKRQEQEEMWRQEEKI 532
Query: 493 KTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLT 552
+ E++ RQKE K+ H+ K +++EE
Sbjct: 533 R-----EQEEIWRQKE-------------KI--HEQEEKIRKQEEKMW------------ 560
Query: 553 LCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEK----KHRTLHTEELTSKEAD 608
+ E HD+ +K + K+++ EEK + + EE+T ++ +
Sbjct: 561 -------RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613
Query: 609 LTEETEENL----------RSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDI 658
E EE + + +I+E+ ++ + E E + + +M
Sbjct: 614 KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673
Query: 659 LEERIDSLEDQIEEFSKDTMQMTKQIISKE-RQRDIEER 696
EE++ E++++E + + +++ +E R R EE+
Sbjct: 674 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 712
Score = 58.2 bits (139), Expect = 3e-08
Identities = 85/445 (19%), Positives = 188/445 (42%), Gaps = 54/445 (12%)
Query: 18 KKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKNDL 77
K++N ++ QL E++K + L K++ + + K+L+ Q L E + L +L
Sbjct: 281 KEKNAKLQEKLQLVESEKS---EIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLGKEL 335
Query: 78 KAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNENLTFKL 137
++V E N ++ + +++ + KI+ + KI + E
Sbjct: 336 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE------ 389
Query: 138 EVNELSGKLDNTNEYNSNDGKKLPQGES----------RSYEVMGSMEETLCNIDDRDGN 187
++ E K+ E +K+ + E R E+M EE + ++++
Sbjct: 390 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 449
Query: 188 RNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVA 247
+ + E+E ++ E++ ++ + + + K+ +EE ++ +EEK+ E
Sbjct: 450 QE---KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR-EQEEKIREQE-------- 497
Query: 248 DLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKS 307
K W E E + + E + + + + ++ + QK
Sbjct: 498 ---------EKMWRQ-----EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 308 SVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAK 367
+ E + + Q+E++ + K QE++ + + R E + + +E K+ +
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603
Query: 368 PEEMKNLETQEEEFSELEE-LDEEASGMEDDEDTSGLEEEE--EEPSGLEEEEEE--EAS 422
EEM + QEE+ E EE + E+ M++ E+ +EE+ E+ + E+EE+ E
Sbjct: 604 QEEMT--QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 661
Query: 423 GLEEDEASGLEEEEEQTSEQDSTFQ 447
+ +++ + E+EE+ EQ+ Q
Sbjct: 662 EMMQEQEEKMWEQEEKMCEQEEKMQ 686
Score = 52.8 bits (125), Expect = 1e-06
Identities = 73/407 (17%), Positives = 168/407 (41%), Gaps = 44/407 (10%)
Query: 305 QKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVK 364
+ + ++E L+ V +K EI ++ + +R K L+ + E G KE++
Sbjct: 283 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG------KELQ 336
Query: 365 VAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEE---EEA 421
+ +E + E ++ L + EE ++++ E+ +E+ + E+EE E+
Sbjct: 337 SVSAKLQAQVE-ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 395
Query: 422 SGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEE 481
+ E E+EE+ +++ ++ + + E+ + + + + E E
Sbjct: 396 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 455
Query: 482 EEGKSSETGKVKTTSLTEKKASR--RQKEI--PFSYLVGDSGKKKLVKHQVVHKTQEEEE 537
+E K E K++ +++ ++ RQ+E + + +K + + +H+ ++ E
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515
Query: 538 TAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNL-----SISTGVTKLKKTEEK 592
Q EM E K + I K++K EEK
Sbjct: 516 EEKRQEQE-----------------EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEK 558
Query: 593 KHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDL 652
R E++ +E + E+ E+ R +I+E+ ++ + E E +
Sbjct: 559 MWR--QEEKMHDQEEKIREQEEKVWRQE-----EKIREQEEKIREQEEKIREQEEMTQEQ 611
Query: 653 SSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQ-RDIEERSR 698
+M EE++ E++++E + + ++I +E++ R+ EE+ R
Sbjct: 612 EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 658
Score = 48.1 bits (113), Expect = 3e-05
Identities = 58/297 (19%), Positives = 133/297 (44%), Gaps = 16/297 (5%)
Query: 138 EVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTER 197
++ EL K+ + + K+ + + R E E + +++ R + E+
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI--REQEEKIREQ 496
Query: 198 ESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDIS 257
E + ++E + E + R+ +K + +EE+ R+E+ + ++ + + I
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQEEMW---RQEEKIREQEEIWRQKEKIHEQEEKIR 553
Query: 258 KQWSNVFNILRE-NDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDV 316
KQ ++ + +D E K + + ++ + +I+ + K Q+ ++E +
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR-----EQEEKIREQEEKIREQEEMT 608
Query: 317 LPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLET 376
Q+E++ + K QE++ + + R E + + +E K+ + EEM ++
Sbjct: 609 QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM--MQE 666
Query: 377 QEEEFSELEE-LDEEASGMEDDEDTSGLEEEE--EEPSGLEEEEEEEASGLEEDEAS 430
QEE+ E EE + E+ M++ E+ +EE+ E+ L ++EE+ E EA+
Sbjct: 667 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 723
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 62.8 bits (151), Expect = 1e-09
Identities = 99/438 (22%), Positives = 177/438 (40%), Gaps = 56/438 (12%)
Query: 361 KEVKVAKPEEMKNLETQEEEFSELEELDE-------EASGMEDDEDTSGLEEEEEEPSGL 413
+E+ V+ EE K ++EE E EE + +A+ E E+ EEEE G
Sbjct: 478 EELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEE----GQ 533
Query: 414 EEEEEE---------EASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDG 464
EEEEEE E G E++ +S EE E++ E ++ +G +AK E ++
Sbjct: 534 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE-AEAKEEKKVEEKS 592
Query: 465 ME-TTFIDSVEDSESEEEEEGKS-------SETGKVKT-TSLTEKKASRRQKEIPFSYLV 515
E T + V D++ E+ E+ KS E GK S E+K + P V
Sbjct: 593 EEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP----V 648
Query: 516 GDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHT 575
+ GK + K V K + + P + +P + E+ E K+
Sbjct: 649 EEKGKSPVPKSPVEEKGKSPVSKS-PVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK 707
Query: 576 NLSISTGVTKLKKTEE--------KKHRTLHTEELTSKEADLTEETEENLRSSVINSIRE 627
+ + K++K EE KK + EE ++ +T+ + +L +
Sbjct: 708 EVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKP 767
Query: 628 IKEEIGNLKSSHSGVLEIENSVDDL--SSRMDILEERIDSLEDQIEEFSKDTMQMTKQII 685
+++E K+ G E E S S + DI ++++E+ +K+
Sbjct: 768 LQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKE--------- 818
Query: 686 SKERQRDIEERSRSCNIRLIGIPEKESYENRAED-IIKEIIDENFAELKKGSSLEIVSAC 744
K R+ E+ + + L EK+ + E ++ + +++ +E G++ I +
Sbjct: 819 -KGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSV 877
Query: 745 RVPSKIDEKRLTPRHILV 762
V K++E T LV
Sbjct: 878 TVTQKVEEHEETFEEKLV 895
Score = 53.9 bits (128), Expect = 6e-07
Identities = 123/562 (21%), Positives = 216/562 (38%), Gaps = 113/562 (20%)
Query: 9 QSKFARLAKKKENITYMKREQLT-----ETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQD 63
+++F+ A Y R +T + K AP L ++ K V I+ + KV E +
Sbjct: 409 ETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSE 468
Query: 64 L------MFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVG 117
+ + EE+ ++K + K K PE + E ++ ++ + ++ G
Sbjct: 469 MEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKE 528
Query: 118 KIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEET 177
+ EG+ E ++G K Q E E GS E+
Sbjct: 529 EEEGQE--------------------------EEEEEDEGAKSDQAEEGGSEKEGSSEK- 561
Query: 178 LCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMRE-ERKFQKLKNKEEVLKASREEKVL 236
+G + E E E+ +GE+ KE ++ E K +++ KEE++ ++ EK
Sbjct: 562 ------EEGEQ----EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 611
Query: 237 MDEGAV-LTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSD 295
+ V + V + + + S + + ++ E K V S
Sbjct: 612 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK-----------SP 660
Query: 296 LQSLRKFASQKSSVKELLKDVLPQ--------KEEINQGGRKYGIQEKRDKTLIDSKHRA 347
++ K KS V+E K +P+ K E+ +G +K E+ +K + ++
Sbjct: 661 VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQK----EEEEKEVKEAP--- 713
Query: 348 GEITSDGLSFLFLKEVKVAKPEEMKN--LETQEEEFSELEELDEEASGMEDDEDTSGLEE 405
KE KV K EE E ++ E EE E + +E
Sbjct: 714 -------------KEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKE 760
Query: 406 EEEEPSGLEEEEEEEASGLE-EDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITS-- 462
+EE L++E+E+E +G E E G ++ + + ++D G V+ K EVE +
Sbjct: 761 TKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGE--VEGKEEVEQETKE 818
Query: 463 --DGMET---TFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGD 517
G E + ++ S ++E++ G SE KV T EK S GD
Sbjct: 819 KGSGREEEKGVVTNGLDLSPADEKKGGDKSEE-KVVVTKTVEKITSEG----------GD 867
Query: 518 SGKKKLVKH-QVVHKTQEEEET 538
K + K V K +E EET
Sbjct: 868 GATKYITKSVTVTQKVEEHEET 889
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 62.8 bits (151), Expect = 1e-09
Identities = 98/435 (22%), Positives = 175/435 (40%), Gaps = 50/435 (11%)
Query: 361 KEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEE---EEPSGLEEEE 417
+E+ V+ EE K ++EE E EE + A ++EEE EE G +EEE
Sbjct: 102 EELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG-QEEE 160
Query: 418 EEEASGLEEDEA----------SGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGME- 466
EEE G + D+A S EE E++ E ++ +G +AK E ++ E
Sbjct: 161 EEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE-AEAKEEKKVEEKSEEV 219
Query: 467 TTFIDSVEDSESEEEEEGKS-------SETGKVKT-TSLTEKKASRRQKEIPFSYLVGDS 518
T + V D++ E+ E+ KS E GK S E+K + P V +
Sbjct: 220 ATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP----VEEK 275
Query: 519 GKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLS 578
GK + K V K + + P + +P + E+ E K+ +
Sbjct: 276 GKSPVPKSPVEEKGKSPVSKS-PVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK 334
Query: 579 ISTGVTKLKKTEE--------KKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKE 630
+ K++K EE KK + EE ++ +T+ + +L + +++
Sbjct: 335 EAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQ 394
Query: 631 EIGNLKSSHSGVLEIENSVDDL--SSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKE 688
E K+ G E E S S + DI ++++E+ +K+ K
Sbjct: 395 EKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKE----------KG 444
Query: 689 RQRDIEERSRSCNIRLIGIPEKESYENRAED-IIKEIIDENFAELKKGSSLEIVSACRVP 747
R+ E+ + + L EK+ + E ++ + +++ +E G++ I + V
Sbjct: 445 SGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVT 504
Query: 748 SKIDEKRLTPRHILV 762
K++E T LV
Sbjct: 505 QKVEEHEETFEEKLV 519
Score = 53.9 bits (128), Expect = 6e-07
Identities = 123/562 (21%), Positives = 216/562 (38%), Gaps = 113/562 (20%)
Query: 9 QSKFARLAKKKENITYMKREQLT-----ETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQD 63
+++F+ A Y R +T + K AP L ++ K V I+ + KV E +
Sbjct: 33 ETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSE 92
Query: 64 L------MFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVG 117
+ + EE+ ++K + K K PE + E ++ ++ + ++ G
Sbjct: 93 MEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKE 152
Query: 118 KIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEET 177
+ EG+ E ++G K Q E E GS E+
Sbjct: 153 EEEGQE--------------------------EEEEEDEGAKSDQAEEGGSEKEGSSEK- 185
Query: 178 LCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMRE-ERKFQKLKNKEEVLKASREEKVL 236
+G + E E E+ +GE+ KE ++ E K +++ KEE++ ++ EK
Sbjct: 186 ------EEGEQ----EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 235
Query: 237 MDEGAV-LTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSD 295
+ V + V + + + S + + ++ E K V S
Sbjct: 236 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK-----------SP 284
Query: 296 LQSLRKFASQKSSVKELLKDVLPQ--------KEEINQGGRKYGIQEKRDKTLIDSKHRA 347
++ K KS V+E K +P+ K E+ +G +K E+ +K + ++
Sbjct: 285 VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQK----EEEEKEVKEAP--- 337
Query: 348 GEITSDGLSFLFLKEVKVAKPEEMKN--LETQEEEFSELEELDEEASGMEDDEDTSGLEE 405
KE KV K EE E ++ E EE E + +E
Sbjct: 338 -------------KEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKE 384
Query: 406 EEEEPSGLEEEEEEEASGLE-EDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITS-- 462
+EE L++E+E+E +G E E G ++ + + ++D G V+ K EVE +
Sbjct: 385 TKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGE--VEGKEEVEQETKE 442
Query: 463 --DGMET---TFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGD 517
G E + ++ S ++E++ G SE KV T EK S GD
Sbjct: 443 KGSGREEEKGVVTNGLDLSPADEKKGGDKSEE-KVVVTKTVEKITSEG----------GD 491
Query: 518 SGKKKLVKH-QVVHKTQEEEET 538
K + K V K +E EET
Sbjct: 492 GATKYITKSVTVTQKVEEHEET 513
Score = 30.4 bits (67), Expect = 7.4
Identities = 47/210 (22%), Positives = 90/210 (42%), Gaps = 27/210 (12%)
Query: 204 EDEFVKEMREERKFQKLKNKEEVLKASREEKVL---MDEGAVLTLVADLSSATLDISKQW 260
++E KE++E K +K++ KEE K E+K + E AV +V S + + K+
Sbjct: 326 KEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKET 385
Query: 261 SNVFNILRENDFEPKFLCE---------------VKLAFKCDGEIKTFSDLQSLRKFASQ 305
L++ + K E K +GE++ +++ K +
Sbjct: 386 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETK---E 442
Query: 306 KSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITS---DGLSFLFLKE 362
K S +E K V+ +++ K G + +K ++ +ITS DG + K
Sbjct: 443 KGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTK--TVEKITSEGGDGATKYITKS 500
Query: 363 VKVAKPEEMKNLETQEEEFSELEELDEEAS 392
V V + E ++ ET EE+ +++++ S
Sbjct: 501 VTVTQKVE-EHEETFEEKLVSTKKVEKVTS 529
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 62.4 bits (150), Expect = 2e-09
Identities = 159/842 (18%), Positives = 338/842 (40%), Gaps = 90/842 (10%)
Query: 17 KKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKND 76
++KE + QL++T + A ++ KD +F+ + + + E ++ + D
Sbjct: 193 QEKEEFISTLQAQLSQTQAEQAAQQVVREKDA-----RFETQVRLHE--DELLQLVTQAD 245
Query: 77 LKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNENLTFK 136
++ + K + + K E+ S Q+++L Q+ + E N + + + +
Sbjct: 246 VETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQE---LTAAEQRNQILSQQLQQM--E 300
Query: 137 LEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNI---DDRDGNRNVHLE 193
E N L ++ E + +K+ + +++E + ++ ++ G LE
Sbjct: 301 AEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELE 360
Query: 194 FT----ERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMD--EGAVLTL-- 245
E++ + + E++ + ++ Q+L++ + LK + K+L D E AV +
Sbjct: 361 SRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALK-DQNSKLLQDKNEQAVQSAQT 419
Query: 246 VADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQ 305
+ L SK+ S N L E + + T ++ SL+K +
Sbjct: 420 IQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVE 479
Query: 306 KSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSD--GLSFLFLKEV 363
+ K L + EE+ K Q TL+++++R GE + +S + +
Sbjct: 480 LENEKGALLLSSIELEELKAENEKLSSQI----TLLEAQNRTGEADREVSEISIVDIANK 535
Query: 364 KVAKPEE-----MKNLETQEEE-----FSELEELDEEASGMEDDEDTSGLEEEEEEPSGL 413
+ + EE ++N +Q+ + E++E EE + ++ EE + E
Sbjct: 536 RSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQ 595
Query: 414 EEEEEEEASGL---------------------EEDEASGLEEEEEQTSEQDSTFQGHTLV 452
+E ++ E G+ EE +E+E+ T Q T + +L
Sbjct: 596 KEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLN 655
Query: 453 DAKHEVEITS-DGMET-TFIDSVEDSESEEEEEGKSS----ETGKVKTTSLTEKKASRRQ 506
DA E++ T DG ++ + + + +E E KS E K + EK +
Sbjct: 656 DAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKA 715
Query: 507 KEIPFSYLVGDSGKKKLVKHQVVHKTQEEE---------ETAVPTSQGTGTPCLTLCLAS 557
KEI + + KK + EE E ++ T L + LA
Sbjct: 716 KEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAE 775
Query: 558 PSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETE--E 615
+ + ++ H + ++ K+++ K L E L + +E++
Sbjct: 776 AERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNE-LDDVQLQFSEQSTLIR 834
Query: 616 NLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLS---SRMD--ILEER--IDSLED 668
+L+S + N E+ E ++ S V E+ ++ ++MD +LE++ +++L+
Sbjct: 835 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQ 894
Query: 669 QIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDEN 728
IEE + +++ + K Q + E S + + + E+ + +RAE+ KE ++E+
Sbjct: 895 TIEEKDQQVTEISFSMTEKMVQ--LNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEED 952
Query: 729 FAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRERREITYQGT 788
E+ G + +I ++ L L+K N K K+ A R+E+ + +
Sbjct: 953 -NEVSSGLK-QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS 1010
Query: 789 RI 790
R+
Sbjct: 1011 RL 1012
Score = 61.6 bits (148), Expect = 3e-09
Identities = 161/822 (19%), Positives = 303/822 (36%), Gaps = 144/822 (17%)
Query: 28 EQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKNDLKAVLGGKATI 87
E L ++ + L+ + + KF+ LM +D + EE+++ LK+ ++ + +A +
Sbjct: 1715 ETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQD-LKHQIEGNVSKQANL 1773
Query: 88 PEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNEL----- 142
+ +N ++ TE EG S G+ E + +
Sbjct: 1774 EATEKHDNQTNVTE------------------EGTQSIPGETEEQDSLSMSTRPTCSESV 1815
Query: 143 -SGKLDN---TNEYNSND--GKKLPQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTE 196
S K N + +++S+D L Q + + G EE N + N
Sbjct: 1816 PSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLS 1875
Query: 197 RESRKDGEDEFVKE------------MREERKFQKLKNKEEVLKASREEKVLMD----EG 240
+ S KDGE + ++E E + KLK E K EE+++ G
Sbjct: 1876 QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNG 1935
Query: 241 AVLTLVADLSSATLD---ISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQ 297
++ D++ A + + + N+ + E + E + L + K + + + +Q
Sbjct: 1936 SIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQ 1995
Query: 298 SLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSF 357
+K KS KEL + + +++E+ Q ++D K A E T L F
Sbjct: 1996 GAQKEPGNKSHAKELQELLKEKQQEVKQ--------LQKDCIRYQEKISALERTVKALEF 2047
Query: 358 LFL---KEVKVAKPEEMKNLETQEEEFSELEEL-----DEEASGMEDDEDTSGLEEE--- 406
+ K++++ K + +E +++ +EL D ++ D L++E
Sbjct: 2048 VQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQS 2107
Query: 407 --EEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGH------------TLV 452
E S +++++E+ LE+ E L+E++ + D+ + TL
Sbjct: 2108 NKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLN 2167
Query: 453 DAKHEVEITSDGMETTF---------IDSVEDSESEEEEEGKSSETGKVKTTSLTEKKAS 503
EV+ + +++T + S++D +E K E + + ++ K+
Sbjct: 2168 KKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWE--RKFSDAIQSKEEE 2225
Query: 504 RRQKEIPFSYLVGDSGKK-------KLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLA 556
R KE S L + K+ ++ H Q E A Q C TL
Sbjct: 2226 IRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGE 2285
Query: 557 SPSKSLEMSHDEHKKHSHTN---------LSISTGVTKLKKTEEK--------------- 592
+ ++ H HS N S+ +T L + EK
Sbjct: 2286 NKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ 2345
Query: 593 ---------KHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEE-----IGNLKSS 638
+ L T+ S+E E N++ I S+ KEE I L+
Sbjct: 2346 EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQ 2405
Query: 639 HSG-VLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRD--IEE 695
H + E+EN + +LEE D+ + + + K+ I ++ Q D ++
Sbjct: 2406 HDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKS 2465
Query: 696 RSRSCNIRLIGIPEKESYENRAEDIIKE---IIDENFAELKK 734
S N R + + + E R II E +I E AE K
Sbjct: 2466 MSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNK 2507
Score = 55.1 bits (131), Expect = 3e-07
Identities = 161/865 (18%), Positives = 353/865 (40%), Gaps = 122/865 (14%)
Query: 1 MSDVSTSVQSKFARLAKKKENITYMK---REQLTETDKDIAPVLDLKCKDVSAIMNKFKV 57
M+ ++ +Q + +R+ K KE K E+L ++ + C+DV+ K ++
Sbjct: 1894 MNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNEL 1953
Query: 58 L-MEIQDL------MFEEMRETLKNDLKAVLG-GKATIPEVKNSE----NSSSRTEFQQI 105
L E+++L + EE ++ +K K K + +++ ++ N S E Q++
Sbjct: 1954 LESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQEL 2013
Query: 106 INLALQKTGMVGK----IEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLP 161
+ Q+ + K + + S + + L F ++ ++ N + + +K
Sbjct: 2014 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKA 2073
Query: 162 QGESRSYEVM---GSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVK---EMREER 215
Q E S++V+ E D+ + + +S+ +DE ++ E EE+
Sbjct: 2074 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEK 2133
Query: 216 KFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPK 275
++ KN +E L A R EKV ++E + + L+ ++ + N+ + + + K
Sbjct: 2134 HLKEKKNMQEKLDALRREKVHLEE-TIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTK 2192
Query: 276 FLCEV-----KLAFKCDGEIKTFSD-LQSLRKFASQKSSVKELLKDVLPQKEEINQGGRK 329
+ + ++ + + FSD +QS + K +LKD L Q I+ K
Sbjct: 2193 SMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQM-SIHMEELK 2251
Query: 330 YGIQE-KRDKTLIDSKHRAGEITSDGLSFLFLKEVK--VAKPEEMKNLETQEEEFSELEE 386
I + DK + +SK + + E K +++ EE ++L + +EL +
Sbjct: 2252 INISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQ--NELAK 2309
Query: 387 LDEEASGMEDD--EDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDS 444
L+ E ++D + ++ LE+ +E+ LE ++ + ++ + S + E + + ++
Sbjct: 2310 LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASREL 2369
Query: 445 TFQGHTLVDAKHEVEIT------------------SDGMETTFIDSVEDSESEE----EE 482
T + H ++ K + I+ E ++++ E EE EE
Sbjct: 2370 TSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEE 2429
Query: 483 EGKSS--ETGKVKTTSLTEKKASRRQKEIPFSY-------------LVGDSGKKK----- 522
E K + +T ++ T T KK + +QK S+ +VGD + +
Sbjct: 2430 ENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLS 2489
Query: 523 --LVKHQVVHKTQEEEETAVPTSQGTGT------------------------PCLTLCLA 556
L K Q++ + E +G + +T+ +
Sbjct: 2490 IILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDS 2549
Query: 557 SPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEEN 616
+ LE+ ++K+ + + + + ++ E R+ + L ++ DL++E E+
Sbjct: 2550 QQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNA--LQEEKQDLSKEI-ES 2606
Query: 617 LRSSVINSIREIK--EEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFS 674
L+ S+ R++ +E G L H+ + E V LS+ ++RI LE+++
Sbjct: 2607 LKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQ 2666
Query: 675 KDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDEN-----F 729
K+ + +I K +++++ I E E+ E R ++ +++++
Sbjct: 2667 KEAAKKVGEIEDK-LKKELKHLHHDAGIMR---NETETAEERVAELARDLVEMEQKLLMV 2722
Query: 730 AELKKGSSLEIVSACRVPSKIDEKR 754
+ KG + +I S R S + R
Sbjct: 2723 TKENKGLTAQIQSFGRSMSSLQNSR 2747
Score = 50.4 bits (119), Expect = 7e-06
Identities = 117/700 (16%), Positives = 277/700 (39%), Gaps = 81/700 (11%)
Query: 13 ARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRET 72
A+ ++K + +E+ +D VL + + +S M + K+ + E ++
Sbjct: 2208 AKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINIS----RLEHDKQI 2263
Query: 73 LKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNEN 132
++ + + + + + EN ++ ++ +L + K+E E + D
Sbjct: 2264 WESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKD---- 2319
Query: 133 LTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNID-DRDGNRNVH 191
++ +LS L+ E N + Q E+ S E+ ++ R+ +H
Sbjct: 2320 -----QLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLH 2374
Query: 192 LEFTERESR----KDGEDEFVK----EMREERKFQKLKNKEEVLKASREEKVLMDEGAVL 243
E +E + G++E ++ E+R++ +++K E +L EE ++++E
Sbjct: 2375 EEINMKEQKIISLLSGKEEAIQVAIAELRQQHD-KEIKELENLLSQEEEENIVLEEE--- 2430
Query: 244 TLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLR-KF 302
+ +D + Q +++ + + K + D +K+ S LQ+ R +
Sbjct: 2431 ------NKKAVDKTNQLMETLKTIKKENIQQKA--------QLDSFVKSMSSLQNDRDRI 2476
Query: 303 ASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRD-----KTLIDSKHRAGEITSDGLSF 357
++E ++ +K+++ Q + K + + D ++ ++ + +
Sbjct: 2477 VGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQY 2536
Query: 358 LF-LKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDD--EDTSGLEEEEEEPSGLE 414
L +V K + K L E + + +EL+ + + +E+ E E+ + L+
Sbjct: 2537 REDLNQVITIKDSQQKQL--LEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQ 2594
Query: 415 EEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVE 474
EE+++ + +E + S + + T+ Q+ G L A+ +V+ + S +
Sbjct: 2595 EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLG--LYHAQLKVKEEEVHRLSALFSSSQ 2652
Query: 475 DSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQE 534
+E EEE + K E K + K +L D+G + ++T+
Sbjct: 2653 KRIAELEEELVCVQKEAAKKVGEIEDKLKKELK-----HLHHDAGIMR-------NETET 2700
Query: 535 EEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKH 594
EE ++ L + L M E+K + S ++ L+ + + H
Sbjct: 2701 AEERVAELARD---------LVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRD--H 2749
Query: 595 RTLHTEELTSKEADLTEETEENLRSSVINSIRE--IKEEIGNLKSSHSGVLEIENSVDDL 652
+EL K +E + ++N R+ + E ++ S+ L + ++ L
Sbjct: 2750 ANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSL---SHLEKL 2806
Query: 653 SSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRD 692
+ ++ +E++ L Q+E+ +K + S + +RD
Sbjct: 2807 NQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERD 2846
Score = 50.4 bits (119), Expect = 7e-06
Identities = 131/751 (17%), Positives = 299/751 (39%), Gaps = 94/751 (12%)
Query: 7 SVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMF 66
S Q++ A+L + +++ ++QLT+ + KCK+ + E
Sbjct: 2302 SSQNELAKLESELKSL----KDQLTDLSNSLE-----KCKEQKGNLEGIIRQQEADIQNS 2352
Query: 67 EEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKI 126
+ E L+ DL+A + + E N + Q+II+L + GK E I
Sbjct: 2353 KFSYEQLETDLQASRELTSRLHEEINMKE-------QKIISL------LSGKEEAIQVAI 2399
Query: 127 GDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDG 186
+ + E+ EL L E N L + ++ + + ETL I +
Sbjct: 2400 AELRQQ--HDKEIKELENLLSQEEEENI----VLEEENKKAVDKTNQLMETLKTIKKENI 2453
Query: 187 NRNVHLE--FTERESRKDGEDEFVKEMR--EERKFQKLKNKEEVLK--ASREEKVLMDEG 240
+ L+ S ++ D V + + EER + K+++++ A+ K+ +
Sbjct: 2454 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIR 2513
Query: 241 AVLTLVADLSS--ATLD--ISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDL 296
+ + + DL+S A LD + + ++ ++ D + K L EV+L + E K
Sbjct: 2514 GLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLE 2573
Query: 297 QSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLS 356
+ L++ ++ + +K+++++ E ++ + + +G
Sbjct: 2574 EKLKESEEANEDLRRSFNALQEEKQDLSKE------IESLKVSISQLTRQVTALQEEGTL 2627
Query: 357 FLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEE 416
L+ ++KV + E + + EL+EE ++ +E ++ +E++
Sbjct: 2628 GLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQ--------KEAAKKVGEIEDK 2679
Query: 417 EEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEV------------EITSDG 464
++E L D +G+ E +T+E+ LV+ + ++ +I S G
Sbjct: 2680 LKKELKHLHHD--AGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFG 2737
Query: 465 METTFIDSVEDSESEEEEEGKSSETGKVKTTS-LTEKKASRRQKEIPFSYLVGDSGKKKL 523
+ + + D +EE +E K +K + L E+ R+++ S +
Sbjct: 2738 RSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTE- 2796
Query: 524 VKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTG- 582
++ + H + ++ Q L S LE S+++ + S S+
Sbjct: 2797 -ENSLSHLEKLNQQLLSKDEQ----------LLHLSSQLEDSYNQVQSFSKAMASLQNER 2845
Query: 583 ------VTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLK 636
+ K +K+EE K R+ + E ++ + SS+ N + +E+ NL+
Sbjct: 2846 DHLWNELEKFRKSEEGKQRSAAQPSTSPAEV----QSLKKAMSSLQNDRDRLLKELKNLQ 2901
Query: 637 SSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQR---DI 693
+ + + + L +++ +++ + + EE ++ + ++ ++ +I
Sbjct: 2902 QQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEI 2961
Query: 694 EERSRSCNIRLIGIPEKESYENRAEDIIKEI 724
ER R L+ I +K+ + +++I+E+
Sbjct: 2962 HER-RMKEQYLMAISDKDQQLSHLQNLIREL 2991
Score = 49.3 bits (116), Expect = 2e-05
Identities = 148/815 (18%), Positives = 312/815 (38%), Gaps = 85/815 (10%)
Query: 8 VQSKFARLAKKKENITYMKREQLT----------ETDKDIAPVLDLKCKDVSAIMNKFKV 57
++ K L K+KE + +E LT E ++ + L + D + + +F
Sbjct: 1162 LEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDE 1221
Query: 58 LMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVG 117
+ + + +++R+ L+ ++ + GK +P E+ SS ++ + A ++
Sbjct: 1222 QSKENENIGDQLRQ-LQIQVRESIDGK--LPSTDQQESCSSTPGLEEPLFKATEQHHTQP 1278
Query: 118 KIEG-----------ENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESR 166
+E + S + K ++ E+ + S+ +L +
Sbjct: 1279 VLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEE 1338
Query: 167 SYEVMGSMEETLCNIDD-RDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEE 225
+++ + + I+ + + + + + + + + R+ Q ++ +
Sbjct: 1339 VFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQ 1398
Query: 226 VLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKF--------- 276
L + +EE V G + A L+ +I +Q + + + + + K
Sbjct: 1399 KLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQ 1458
Query: 277 --LCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQE 334
LCE+K + GE ++ + Q RK + S KE LK+ +EE++ G E
Sbjct: 1459 VELCEMKQKPEEIGE-ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLAR---GTIE 1514
Query: 335 KRDKTLID------SKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELD 388
+ K+L D ++++ + L+ L + K+ + LE Q S E L
Sbjct: 1515 RLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLS-SSCESLK 1573
Query: 389 EEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLE-EDEASGLEEEEEQTSEQDSTFQ 447
G+ +D++ E E + S + E E + E + E L + E S + Q
Sbjct: 1574 LALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQ 1633
Query: 448 GHTLVDAKHE----------VEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSL 497
H + + E E E ++ ++ E +E+ K +++ + K L
Sbjct: 1634 -HVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILEL 1692
Query: 498 TEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLAS 557
E+ R + P GD+ K+ + + + +EE V T + L S
Sbjct: 1693 EEENDRLRAEVHP----AGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQ-SLMS 1747
Query: 558 PSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENL 617
SL + K N+S L+ TE+ ++T TEE T TEE +
Sbjct: 1748 EKDSLSEEVQDLKHQIEGNVSKQAN---LEATEKHDNQTNVTEEGTQSIPGETEEQDSLS 1804
Query: 618 RSS------VINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIE 671
S+ + S + + SSH + +D L R+ LEE ++ +
Sbjct: 1805 MSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQ 1864
Query: 672 EFSKDTMQMTKQIISKERQ-RDIEERSRSCNIRLIGIPE--------KESYENRAEDIIK 722
+ + QI +K+ + + ++E N+ I E KE+ E +D+ +
Sbjct: 1865 TLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEE 1924
Query: 723 EIIDENFAELKK--GSSLEIVSACRVPSKIDEKRL 755
++++ AEL G+ + V+ ++ +++ E +
Sbjct: 1925 RLMNQ-LAELNGSIGNYCQDVTDAQIKNELLESEM 1958
Score = 40.4 bits (93), Expect = 0.007
Identities = 86/430 (20%), Positives = 170/430 (39%), Gaps = 71/430 (16%)
Query: 292 TFSDLQSLRKFASQKS-SVKELL--KDV-LPQKEEINQGGRKYGIQEKRDKTLIDSKHRA 347
T D+Q +A Q +K+++ KDV L QK+E Q RK K K + +K +
Sbjct: 46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERK-AADNKIKKLKLHAKAKL 104
Query: 348 GEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEE 407
+ +++E+K + EE+ S+ ++ E ME ++ L+E+E
Sbjct: 105 TSLNK------YIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEE-MEIEKIKHKLQEKE 157
Query: 408 EEPSGLEEE------EEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEIT 461
E S L+ + E+ S E +E ++++ ++ E ST Q +++
Sbjct: 158 ELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQA----------QLS 207
Query: 462 SDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKK 521
E V + ++ E + + E ++ + + + +QK + + +
Sbjct: 208 QTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEES 267
Query: 522 KLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSIST 581
+ + QVV Q+E A +Q L+ + +E H+ + T S
Sbjct: 268 LVGRAQVVDLLQQELTAAEQRNQ---------ILSQQLQQMEAEHNTLRNTVETEREESK 318
Query: 582 GVTKLKKTE-EKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSH- 639
+ L+K E E R L L + L E+ E+ ++ E++ L+ H
Sbjct: 319 IL--LEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQA-----ELESRYSALEQKHK 371
Query: 640 -------SGVLEIENSVDDLSSRMDILEER------------------IDSLEDQIEEFS 674
S +L ++ + +L S D L+++ I LEDQ+++ S
Sbjct: 372 AEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKS 431
Query: 675 KDTMQMTKQI 684
K+ Q ++
Sbjct: 432 KEISQFLNRL 441
Score = 36.2 bits (82), Expect = 0.13
Identities = 99/508 (19%), Positives = 188/508 (37%), Gaps = 94/508 (18%)
Query: 195 TERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASR------------------EEKVL 236
+E + K + +EM E+ KL+ KEE++ + EE V+
Sbjct: 128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVM 187
Query: 237 MD------EGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEI 290
M E + TL A LS + + Q ++RE D +F +V+L ++
Sbjct: 188 MKQQLQEKEEFISTLQAQLSQTQAEQAAQ-----QVVREKD--ARFETQVRLHEDELLQL 240
Query: 291 KTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEI 350
T +D+++ + +L+ L + EE G + +++ T + ++ +I
Sbjct: 241 VTQADVET------EMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRN---QI 291
Query: 351 TSDGLSFLFLKEVKVAKPEEMKN-LETQEEEFS------ELEELDEEASGMEDDEDTSGL 403
S L + A+ ++N +ET+ EE ELE + + S E+ L
Sbjct: 292 LSQQLQQM------EAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHL 345
Query: 404 EEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSD 463
E+ E+ + E E S LE+ + E EE+TS H + +
Sbjct: 346 LEQFEQAGQAQAELESRYSALEQKHKA---EMEEKTS---------------HILSLQKT 387
Query: 464 GME-TTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKK 522
G E + D+++D S+ ++ +T E + ++ KEI +
Sbjct: 388 GQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEI-----------SQ 436
Query: 523 LVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTG 582
+ + + + +T+ P GT +T SL+ E + L S
Sbjct: 437 FLNRLPLQQHETASQTSFPDVYNEGTQAVT---EENIASLQKRVVELENEKGALLLSSIE 493
Query: 583 VTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGV 642
+ +LK EK + E ++ + E E + N EE SG
Sbjct: 494 LEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEE--------SGQ 545
Query: 643 LEIENSVDDLSSRMDILEERIDSLEDQI 670
+EN+ + +L + +++I
Sbjct: 546 DVLENTFSQKHKELSVLLLEMKEAQEEI 573
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 62.0 bits (149), Expect = 2e-09
Identities = 141/730 (19%), Positives = 303/730 (41%), Gaps = 134/730 (18%)
Query: 7 SVQSKFARLAKKKENITYMKREQLTET-DKDIAPVLD---------LKCKDVSAIMNKFK 56
++++K ++ K+KEN R +L + D+ + + D +K K++ + K
Sbjct: 648 ALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCN 707
Query: 57 VLMEIQDLMFEEMRETLKNDL------KAVLGGKATIPEVKNSENSSSRTEFQQIINLAL 110
++ D +++ T + L KA GK+ + +++ ++ + QI +L +
Sbjct: 708 EQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEK----QIKHLEI 763
Query: 111 QKTGMVGK-------IEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQG 163
+K K ++G K+ + ENL+ EV+++ L+ + +K +
Sbjct: 764 EKNAESSKASSITRELQGRELKLTNLQENLS---EVSQVKETLEKELQILK---EKFAEA 817
Query: 164 ESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTE--RESRKDGEDEFVKEMREERKFQKLK 221
+ V SM+ET+ + ++ N+ E RE+ D E +F + ++ER+ Q +K
Sbjct: 818 SEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFRE--KDEREEQLIK 875
Query: 222 NKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVK 281
KE K+ D ++ + D SS ++ + L+E D E L K
Sbjct: 876 AKE---------KLENDIAEIMKMSGDNSSQLTKMNDELR-----LKERDVEELQLKLTK 921
Query: 282 LAFKCDGEIKTFSDL---------QSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGI 332
K+ D+ ++ +K +K ++ L D+ + E + ++
Sbjct: 922 ANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKA 981
Query: 333 QEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEAS 392
+ +R + +KH EI + L++ + +++K +EE L+EL+E
Sbjct: 982 RYERATSETKTKHE--EILQN------LQKTLLDTEDKLKG--AREENSGLLQELEELRK 1031
Query: 393 GMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLV 452
+ + E+ + + +E+ E + LE+ + + + + E + +++ +
Sbjct: 1032 QADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLK----- 1086
Query: 453 DAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFS 512
VE + E +++ + EE K ET K +++ ++ +++ + +
Sbjct: 1087 ----NVEELNKSKELLTVEN-----QKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLA 1137
Query: 513 YLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKH 572
+G S + ++ HQ + EEE +V +Q L + DE K
Sbjct: 1138 EELGRS-RDEVTSHQKL-----EEERSVLNNQ-------LLEMKKRESKFIKDADEEKAS 1184
Query: 573 SHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEI 632
++SI++ + LT K+A+L E LR N + ++ E
Sbjct: 1185 LQKSISITSAL------------------LTEKDAEL-----EKLR----NEVTVLRGEN 1217
Query: 633 GNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRD 692
+ KS HS V +E+ D + LE ++ +LE Q++E + Q++ + + Q D
Sbjct: 1218 ASAKSLHSVVQTLES--DKVK-----LELKVKNLELQLKE---NKRQLSSSSGNTDTQAD 1267
Query: 693 IEERSRSCNI 702
+ER++ I
Sbjct: 1268 EDERAQESQI 1277
Score = 57.4 bits (137), Expect = 6e-08
Identities = 160/855 (18%), Positives = 326/855 (38%), Gaps = 176/855 (20%)
Query: 13 ARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRET 72
A +AK ++ +++E D VL+L+ K M++ + ++E D E+
Sbjct: 376 AEVAKATSHVGEIEQELALARDGHDQHVLELEAK-----MDQLRTMVEAADREKVELLNQ 430
Query: 73 LKNDLKAVLGGKATIPE---------VKNSENSSSRTEFQQIINLALQKTGMVGKIEGEN 123
L+ + + V + + E V S E ++ + L +Q+ + + N
Sbjct: 431 LEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESN 490
Query: 124 SKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDD 183
GD + +L+ E++ L KL+ T + + L + E + L +
Sbjct: 491 KPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATE 550
Query: 184 RDGNRNVHLEFTERESRKDGED------------------------------------EF 207
+ N L+ + K+ D EF
Sbjct: 551 KLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEF 610
Query: 208 ------VKEMR--EERKFQKLKNKE-----------EVLKASREEKVLMDEGAVLTLVAD 248
+++MR + + + L+N++ E L+A + + E ++ + +
Sbjct: 611 AELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSK 670
Query: 249 LSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFS-------------- 294
L A + + N L+E + + K L EV L KC+ + K
Sbjct: 671 LDKAEDQHLVEMEDTLNKLQEAEIKVKEL-EV-LQAKCNEQTKVIDNFTSQLKATEEKLL 728
Query: 295 DLQSLRKFASQ-KSSVKELLKDVLPQKEEINQ-------------------GGRKY---- 330
DL +LRK +S+ KS +K+L + + +++I GR+
Sbjct: 729 DLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTN 788
Query: 331 ---------GIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEF 381
++E +K L K + E + + +S V+ + E + L +EE+F
Sbjct: 789 LQENLSEVSQVKETLEKELQILKEKFAEASEEAVS------VQRSMQETVNKLHQKEEQF 842
Query: 382 ----SELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEE 437
S+LE+L E + ME E++E E ++ +E+ E E + SG +
Sbjct: 843 NMLSSDLEKLRENLADME----AKFREKDEREEQLIKAKEKLENDIAEIMKMSG--DNSS 896
Query: 438 QTSEQDSTFQGHTLVDAKHEVEITSDGMETTFID-SVED----SESEEEEEGKSSETGKV 492
Q ++ + + + ++++T +F+ S+ED +E ++E K E K
Sbjct: 897 QLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKK 956
Query: 493 KTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLT 552
+ E+K S +K++ S+ K + + KT+ EE
Sbjct: 957 E----LERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEE---------------- 996
Query: 553 LCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEE 612
L + K+L + D+ K N + + +L+K +K E+ +T+E
Sbjct: 997 -ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKE 1055
Query: 613 TEENLRS--SVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQI 670
E L S + +++ E+ LK ++ +E N +L + + ++++ +I
Sbjct: 1056 KTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKEL---LTVENQKMEEFRKEI 1112
Query: 671 EEFSKDTMQMTKQI--ISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDEN 728
E + Q ++Q+ + +E + EE RS + E S++ E+ + +++
Sbjct: 1113 ETLKQAAAQKSQQLSALQEENVKLAEELGRSRD-------EVTSHQKLEEE--RSVLNNQ 1163
Query: 729 FAELKKGSSLEIVSA 743
E+KK S I A
Sbjct: 1164 LLEMKKRESKFIKDA 1178
Score = 35.4 bits (80), Expect = 0.23
Identities = 41/219 (18%), Positives = 91/219 (41%), Gaps = 31/219 (14%)
Query: 568 EHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEEN-------LRSS 620
E + + +L ++T K + E +K L +E+ A+L E N + S
Sbjct: 446 EEESITKGDLEVATVSEKSRIMELEKDLALRVQEV----AELRRRLESNKPAGDVDMSLS 501
Query: 621 VINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQM 680
++ I ++E++ ++ H EI + + +R + ++ I +L E+ SK+ +
Sbjct: 502 LLQEISSLQEKLEVTRTDHQR--EITSLKEHFGAREETHQKEIKALYTATEKLSKENESL 559
Query: 681 TKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDII---KEIIDENFAELKKGSS 737
++ E + N +I + ++++ E I ++ ++E KG
Sbjct: 560 KSKL----------EHANKENSDVIAL-----WKSKLETAIASHQQAMEELKVSFSKGLG 604
Query: 738 LEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRA 776
E + ++I++ RL +H + N D E+ A
Sbjct: 605 TETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHA 643
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 61.6 bits (148), Expect = 3e-09
Identities = 162/801 (20%), Positives = 306/801 (38%), Gaps = 124/801 (15%)
Query: 13 ARLAKKKENITYMKREQLTETDKDIAPV---LDLKCKDVSAIMNKFKVLMEIQDLMFEEM 69
A L KK + ++ +E KDI + L K+ A NK K L E + E +
Sbjct: 938 AELTAKKRKL----EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETI 993
Query: 70 RETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDD 129
+ K + T+ +++ +E T + I L Q + G +E E KI D
Sbjct: 994 AKLTKEKKALQEAHQQTLDDLQ-AEEDKVNTLTKAKIKLEQQVDDLEGSLEQEK-KIRMD 1051
Query: 130 NENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQG-ESRSYEVMGSMEETLCNIDDRDGNR 188
E KLE +L ++T + ND ++L + + + +E+ G + I+D
Sbjct: 1052 LERAKRKLE-GDLKLAQESTMDIE-NDKQQLDEKLKKKEFEMSGLQSK----IEDEQA-- 1103
Query: 189 NVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVAD 248
+ ++ ++ E ++E E + + K +++ SRE + + + L
Sbjct: 1104 -LGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISER---LEEAGG 1159
Query: 249 LSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAF----KCDGEIKTFSDLQSLR---- 300
+SA ++++K+ F +R + E E A D + + +L+
Sbjct: 1160 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1219
Query: 301 KFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFL 360
K +KS +K + D+ E +++ G EK + L D L
Sbjct: 1220 KLEKEKSEMKMEIDDLASNMETVSKAK---GNLEKMCRALEDQ----------------L 1260
Query: 361 KEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDT---------SGLEEEEEEPS 411
E+K + E+ + + + + L+ E S D++DT ++ EE
Sbjct: 1261 SEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELK 1320
Query: 412 GLEEEEEEEASGL------EEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGM 465
EEE + S L + L E+ E+ E + Q + A EV
Sbjct: 1321 RQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQ-RAMSKANSEVAQWRTKY 1379
Query: 466 ETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVK 525
ET I E+ E +++ + + + ++ K AS + +
Sbjct: 1380 ETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTK----------------- 1422
Query: 526 HQVVHKTQEEEETAVPTSQGTGTPCLTL---------CLASPSKSLEMSHDEHKKHSHTN 576
+ Q E E + + T C L LA + E +H E + +
Sbjct: 1423 ----QRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKES 1478
Query: 577 LSISTGVTKLKKTEEKKHRTLHT-----EELTSKEADLTEETEENLRSSVINSIREIKEE 631
S+ST + K+K E+ L T + L + +DLTE+ E I+ + +IK++
Sbjct: 1479 RSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG--GKRIHELEKIKKQ 1536
Query: 632 IGNLKSSHSGVL-EIENSVD-----------DLSSRMDILEERIDSLEDQIEEFSKDTMQ 679
+ KS L E E S++ +L+ ++ +I +++I++ ++ ++
Sbjct: 1537 VEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIR 1596
Query: 680 MTKQIISKERQRDIEERSRSCNIRLI-----GIPEKESYENRAEDIIKEIID--ENFAEL 732
+ + S + D E RSR+ IRL + E E N A + E + N +
Sbjct: 1597 IVE---SMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAI 1653
Query: 733 KKGSSLEIVSACRVPSKIDEK 753
K + L + A R + E+
Sbjct: 1654 LKDTQLHLDDALRSQEDLKEQ 1674
Score = 51.2 bits (121), Expect = 4e-06
Identities = 80/343 (23%), Positives = 137/343 (39%), Gaps = 32/343 (9%)
Query: 405 EEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTS----EQDSTFQGHTLVDAKHEVEI 460
E E+E + ++EE E+ L + EA E EE+ + + D Q D+ + E
Sbjct: 848 ETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEE 907
Query: 461 TSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGK 520
D + T I E++ +E + +E + LT KK R+ E S L D
Sbjct: 908 RCDQLIKTKIQL----EAKIKEVTERAEDEEEINAELTAKK---RKLEDECSELKKDIDD 960
Query: 521 KKLVKHQVV-HKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSI 579
+L +V K E + T + G L K+L+ +H +
Sbjct: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK 1020
Query: 580 STGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSH 639
+TK K E +++ E L E E+ +R + + R+++ G+LK +
Sbjct: 1021 VNTLTKAKIKLE--------QQVDDLEGSL--EQEKKIRMDLERAKRKLE---GDLKLAQ 1067
Query: 640 SGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRS 699
++IEN L ++ E + L+ +IE+ MQ+ K+I KE Q IEE
Sbjct: 1068 ESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKI--KELQARIEELEEE 1125
Query: 700 CNIRLIGIPEKESYENRAEDIIKEI--IDENFAELKKGSSLEI 740
+ E + D+ +E+ I E E +S +I
Sbjct: 1126 IEAER---ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1165
Score = 51.2 bits (121), Expect = 4e-06
Identities = 141/686 (20%), Positives = 281/686 (40%), Gaps = 79/686 (11%)
Query: 27 REQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKNDLKAVLGGKAT 86
++ T+ +++ L+ + K SA+ + + DL+ E+ E + + KA L +
Sbjct: 1309 KQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE--EQEAKAELQRAMS 1366
Query: 87 IPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNENLTFKLE-VNELSGK 145
NSE + RT+++ A+Q+T ++E K+ ++ +E VN
Sbjct: 1367 ---KANSEVAQWRTKYETD---AIQRTE---ELEEAKKKLAQRLQDAEEHVEAVNAKCAS 1417
Query: 146 LDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNID-------DRDGNRNVHLEFTERE 198
L+ T + N+ + L R+ ++++ N D + + LE +++E
Sbjct: 1418 LEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKE 1477
Query: 199 SRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISK 258
SR + F + E +L E LK RE K L E ++DL+ + K
Sbjct: 1478 SRSLSTELFKIKNAYEESLDQL----ETLK--RENKNLQQE------ISDLTEQIAEGGK 1525
Query: 259 QWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVK-ELLKDVL 317
+ + I ++ + E E++ A + + E + + + + + VK E+ + +
Sbjct: 1526 RIHELEKIKKQVEQEKS---ELQAALE-EAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1581
Query: 318 PQKEEINQGGRKY-GIQEKRDKTL---IDSKHRAGEITSDGLSFLFLKEVKV-----AKP 368
+ EEI+Q R + I E TL I S++ A + L E+++
Sbjct: 1582 EKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1641
Query: 369 EEMKNLETQEEEFSELE-ELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEED 427
E ++N + + + LD+ ED ++ L E + L+ E EE + LE+
Sbjct: 1642 EALRNYRNTQAILKDTQLHLDDALRSQEDLKEQ--LAMVERRANLLQAEIEELRATLEQT 1699
Query: 428 EASGLEEEEEQTSEQDSTFQGHT----LVDAKHEVEITSDGMETTFIDSVEDSESEEEEE 483
E S E+E + HT L++ K ++E ++ D ++++ + EE+
Sbjct: 1700 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKA 1759
Query: 484 GKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTS 543
K+ + L +++ + E L ++ VK + H+ E E+ A+
Sbjct: 1760 KKAITDAAMMAEELKKEQDTSAHLERMKKNL------EQTVK-DLQHRLDEAEQLALK-- 1810
Query: 544 QGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEK-KHRTLHTEEL 602
G L + + LE + +K + V L+K E K K T TEE
Sbjct: 1811 ---GGKKQIQKLEARVRELEGEVESEQKRN------VEAVKGLRKHERKVKELTYQTEE- 1860
Query: 603 TSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEER 662
K ++ + L++ V + R+ +E + S I++ +++ EER
Sbjct: 1861 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEA-------EER 1913
Query: 663 IDSLEDQIEEFSKDTMQMTKQIISKE 688
D E Q+ + + ++ +IIS+E
Sbjct: 1914 ADIAESQVNKLRVKSREVHTKIISEE 1939
Score = 47.8 bits (112), Expect = 4e-05
Identities = 133/710 (18%), Positives = 271/710 (38%), Gaps = 84/710 (11%)
Query: 54 KFKVLMEIQDLM--FEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQ 111
K ++ MEI DL E + + N K + + E+K E E Q++IN
Sbjct: 1225 KSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEE-----EQQRLINDLTA 1279
Query: 112 KTGMVGKIEGENSKIGDDNENLTFKL---------EVNELSGKLDNTNEYNS-------- 154
+ + GE S+ D+ + L +L ++ EL +L+ + S
Sbjct: 1280 QRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQS 1339
Query: 155 --NDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMR 212
+D L + E ++ + + E T+ R + +E K++
Sbjct: 1340 SRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYE-TDAIQRTEELEEAKKKLA 1398
Query: 213 EERKFQKLKNKEEVLKA------SREEKVLMDEGAVLTLVADL---SSATLDISKQWSNV 263
Q+L++ EE ++A S E+ + V L+ D+ ++A + K+ N
Sbjct: 1399 -----QRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNF 1453
Query: 264 FNILRE-----NDFEPKFLCEVKLAFKCDGEIKTFSDL--QSLRKFASQKSSVKELLKDV 316
IL E + + K + E+ + +SL + + K K L +++
Sbjct: 1454 DKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEI 1513
Query: 317 LPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLET 376
E+I +GG++ EK K + K + + L +E K+ + + N +
Sbjct: 1514 SDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELN-QV 1572
Query: 377 QEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEE 436
+ E ++ E DEE M+ + + E + E +A L++ L E E
Sbjct: 1573 KSEVDRKIAEKDEEIDQMKRNHIR--IVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME 1630
Query: 437 EQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTS 496
Q + + L + ++ I D + D++ E +E+ +
Sbjct: 1631 IQLNHANR-MAAEALRNYRNTQAILKD-TQLHLDDALRSQEDLKEQLAMVERRANLLQAE 1688
Query: 497 LTEKKAS----RRQKEIPFSYLVGDSGKKKLVKHQVVH--KTQEEEETAVPTSQGTGTPC 550
+ E +A+ R ++I L+ S + +L+ Q T+++ ET + QG
Sbjct: 1689 IEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDI 1748
Query: 551 LTLCLASPSKSLE------MSHDEHKKHSHTNLSISTGVTKLKKT-EEKKHRTLHTEELT 603
+ + K+ + M +E KK T+ + L++T ++ +HR E+L
Sbjct: 1749 IQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLA 1808
Query: 604 SK---------EADLTE-----ETEENLRSSVINSIRE----IKEEIGNLKSSHSGVLEI 645
K EA + E E+E+ + +R+ +KE + +L +
Sbjct: 1809 LKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRL 1868
Query: 646 ENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEE 695
++ VD L +++ + + + E+Q ++ ++ E + DI E
Sbjct: 1869 QDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAE 1918
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 60.8 bits (146), Expect = 5e-09
Identities = 138/703 (19%), Positives = 272/703 (38%), Gaps = 104/703 (14%)
Query: 41 LDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRT 100
L+ ++++ +N+ K + D+ + E L + A +A + ++ ++ +
Sbjct: 619 LETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQD 678
Query: 101 EFQQIINLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKL 160
+ Q++ + Q + K++ + +L E E L+ E KKL
Sbjct: 679 KQQELNKITTQLDQVTAKLQDKQEHCSQLESHLK---EYKEKYLSLEQKTEELEGQIKKL 735
Query: 161 PQGESRSYEVMGSMEETLCNIDD-RDGNRNVHLEFTERESRKDGEDEFVKEMREE----- 214
E+ S EV S E+ L ++ R N ++ L TE + + E E V R +
Sbjct: 736 ---EADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKS 792
Query: 215 -------RKFQKLKNKEEVLKA-----SREEKVLMDE--GAVLTLVADLSSATLD----- 255
+K K + ++++LK S+E K+ +E + T V +L ++
Sbjct: 793 EALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALM 852
Query: 256 -----ISKQWSNVFNILR--ENDFEP-------------KFLCEVKLAFKCDGEIKTFSD 295
+ + S V + L+ +++FE K E+K + E T +
Sbjct: 853 TELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQME-NTLKE 911
Query: 296 LQSLRKFASQKSSVKELLK-DVLPQKEEINQGGRKYGIQEKRDKTL----------IDSK 344
+ L+K ++ LK ++ +E++ Q EK ++ L + K
Sbjct: 912 QKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQK 971
Query: 345 HRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLE 404
+ E L L++ ++ + + + +E +E E++ + E ++T +
Sbjct: 972 KKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQET--FK 1029
Query: 405 EEEEEPSGLEEE----------EEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDA 454
+ + + G E E EE+ S +ED L Q Q+ Q L A
Sbjct: 1030 QLQSDFYGRESELLATRQDLKSVEEKLSLAQED----LISNRNQIGNQNKLIQ--ELKTA 1083
Query: 455 KHEVEITSDGMETTFID---SVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPF 511
K +E S E + +++D + E+ + K K K + E K R++KEI
Sbjct: 1084 KATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKC-RQEKEIT- 1141
Query: 512 SYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKK 571
KL + HK + +E L L + SL+ + ++ K+
Sbjct: 1142 ----------KLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKR 1191
Query: 572 HSHT-NLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKE 630
+ + +LKK +K LH+E KE ++ + E + + I + E
Sbjct: 1192 NQQILKDQVKKEEEELKKEFIEKEAKLHSE---IKEKEVGMKKHEENEAKLTMQITALNE 1248
Query: 631 EIGNLK----SSHSGVLEIENSVDDLSSRMDILEERIDSLEDQ 669
+G +K SS V E+E DDL + +LE + + +D+
Sbjct: 1249 NLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDE 1291
Score = 55.8 bits (133), Expect = 2e-07
Identities = 152/762 (19%), Positives = 294/762 (38%), Gaps = 124/762 (16%)
Query: 8 VQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCK--------DVSAIMNKF---K 56
++SK+ +E E +K+ + DLK + DV+ + + +
Sbjct: 175 IKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQ 234
Query: 57 VLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMV 116
LM+ L E E LK++ K + A+ E S+ S + Q + + +Q+ +
Sbjct: 235 TLMDNMTLERERESEKLKDECKKLQSQYAS-SEATISQLRSELAKGPQEVAVYVQE---L 290
Query: 117 GKIEGENSKIGDDNENLTFKL-----EVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVM 171
K++ +++ N+ LT L + +L K + + N L Q + ++
Sbjct: 291 QKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQ 350
Query: 172 GSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASR 231
+ + ++ +H+E +E+ E + E+ E K+Q LK + + L+ R
Sbjct: 351 SRLSASETSL------HRIHVELSEKGEATQKLKEELSEV--ETKYQHLKAEFKQLQQQR 402
Query: 232 EEKVLMDEGAVL-TLVADLSSATLDISKQWSNVFNILREN-------------------- 270
EEK G L + + L S L+ +Q L+E
Sbjct: 403 EEKE--QHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQL 460
Query: 271 -------DFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQK-----SSVKELLKDVLP 318
+ K +L + D + + Q+L++ + K + ++++L+ +
Sbjct: 461 KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGD 520
Query: 319 QKEEIN-------QGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFL-----FLKEVKVA 366
+ ++I + + EK + L +K +AGE + L+ L L+E
Sbjct: 521 KDQKIQNLEALLQKSKENISLLEKEREDLY-AKIQAGEGETAVLNQLQEKNHTLQEQVTQ 579
Query: 367 KPEEMKNLETQEEEFSEL--EELDEEASGMEDDED-TSGLEEEEEEPSGLEEEEEEEASG 423
E++KN ++ E +++ E+ + + +D LE E + E +E+ S
Sbjct: 580 LTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQ 639
Query: 424 LE---EDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGME--TTFIDSVEDSES 478
L+ + + L E + Q + Q H L A++ ++ + TT +D V
Sbjct: 640 LDIQIKAKTELLLSAEAAKTAQRADLQNH-LDTAQNALQDKQQELNKITTQLDQVTAKLQ 698
Query: 479 EEEEEGKSSETG----KVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQE 534
+++E E+ K K SL +K + E L DS + K K Q + Q+
Sbjct: 699 DKQEHCSQLESHLKEYKEKYLSLEQKT---EELEGQIKKLEADSLEVKASKEQALQDLQQ 755
Query: 535 EEETAVPTSQGTGTPCLTLCLASPSKSLEMSHD-------EHKKHSHTNLSISTGVTKLK 587
+ + L L SK LEM + + +K S SI KL
Sbjct: 756 QRQLNTD---------LELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQ---KLT 803
Query: 588 KTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIEN 647
K EE+K E S+E + E N + + ++++K +E E
Sbjct: 804 KQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVK-------------MEKEA 850
Query: 648 SVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKER 689
+ +LS+ D L + DSL++ EF K+ + I+ E+
Sbjct: 851 LMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEK 892
Score = 43.9 bits (102), Expect = 6e-04
Identities = 82/371 (22%), Positives = 147/371 (39%), Gaps = 47/371 (12%)
Query: 342 DSKHRAGEITSDG-LSFLFLKEVKVAK-PEEMKNLETQ-EEEFSELEELDEEASGMEDDE 398
++ H AG + G S L LK V +E+++L+ +EE EEL +E E
Sbjct: 61 EAVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKEL------E 114
Query: 399 DTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEV 458
GL+++E +P GL + E LE ++ EE +E + Q L + K
Sbjct: 115 KYQGLQQQEAKPDGLVTDSSAELQSLE-------QQLEEAQTENFNIKQMKDLFEQK--- 164
Query: 459 EITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEK--KASRRQKEIPFSYL-- 514
+ D +S+ +EE E + K T LTE+ K + +++ L
Sbjct: 165 -------AAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQR 217
Query: 515 --VGDSG--KKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHK 570
+ D KK+LV+ Q + E L AS ++ E
Sbjct: 218 PGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELA 277
Query: 571 KHSHTNLSISTGVTKLKKTEE---KKHRTLHTEELTSKEADLTEETE---------ENLR 618
K + KLK + +K++TL TE L KE D T+ E +N++
Sbjct: 278 KGPQEVAVYVQELQKLKSSVNELTQKNQTL-TENLLKKEQDYTKLEEKHNEESVSKKNIQ 336
Query: 619 SSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTM 678
+++ + ++ L +S + + I + + L+E + +E + + +
Sbjct: 337 ATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFK 396
Query: 679 QMTKQIISKER 689
Q+ +Q KE+
Sbjct: 397 QLQQQREEKEQ 407
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 60.1 bits (144), Expect = 9e-09
Identities = 155/749 (20%), Positives = 301/749 (40%), Gaps = 112/749 (14%)
Query: 15 LAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLK 74
+AK+K+++ ++ +E+D+ L K++ A + + +++ +E ET+
Sbjct: 1440 VAKEKDDLQRLQEVLQSESDQ-----LKENIKEIVAKHLETEEELKVAHCCLKEQEETI- 1493
Query: 75 NDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNENLT 134
N+L+ L K T +I + Q + K++ + +I + E
Sbjct: 1494 NELRVNLSEKET-----------------EISTIQKQLEAINDKLQNKIQEIYEKEEQFN 1536
Query: 135 FKL--EVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMG----SMEETLCNIDDRDGNR 188
K EV E +L E+ L ES+ E+ S EE I +++ +
Sbjct: 1537 IKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMK 1596
Query: 189 NVHLEFT-ERESRKDGEDEFVKEMRE--ERKFQKLKNKEEVLKASREEKVLMDEGAVLTL 245
V ER+ K+ E V +M+E E+++Q LK + A E + M E L
Sbjct: 1597 RVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLK-----MTAVNETQEKMCEIEHLKE 1651
Query: 246 VADLSSATLD-ISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGE-IKTFSDL--QSLRK 301
+ L+ I + + IL EN E + + + + + E +K D ++LR+
Sbjct: 1652 QFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRE 1711
Query: 302 FASQKSSVKELLKDV-LPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFL 360
++ +E LK V + KE + GI ++ I + + E ++D L L
Sbjct: 1712 TITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNE-ISNMQKDLEHSNDALKAQDL 1770
Query: 361 K---EVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSG--LEEEEEEPSGLEE 415
K E+++A + ET ++ + E ++ S M+ D + S L+E+ +E E
Sbjct: 1771 KIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEH 1830
Query: 416 EEEEEASGLEEDE--ASGLEEEEEQTSEQDSTF-----QGHTLVDAKHE--VEITSDGME 466
+ + E + S +E+ ++Q +Q T + L HE E+ S E
Sbjct: 1831 QLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKE 1890
Query: 467 TTFIDSVEDSESEEEEEGKSS--ETG--------KVKTTSLTEKKASRR---------QK 507
+ VE++ E ++ K S ET ++KT + K+ +K
Sbjct: 1891 RDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEK 1950
Query: 508 EIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHD 567
I S + D K K + + + Q++E L L + + MSH
Sbjct: 1951 TIQISDIQKDLDKSKDELQKKIQELQKKE----------------LQLLRVKEDVNMSHK 1994
Query: 568 E-------HKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSS 620
+ K+ NLS+ + + +K H +L + +KE D +E+L+
Sbjct: 1995 KINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKME 2054
Query: 621 VINSIREIKEEIGNLKSSH----------SGVLEIENSVDDLSSRMDILEERIDSLEDQI 670
I ++E I + +H G + S+ + SR+ L +R ++D
Sbjct: 2055 RDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHY 2114
Query: 671 EEFSKDTMQMTKQIISKERQRDIEERSRS 699
E ++ ++ + K+I E Q+++ R ++
Sbjct: 2115 ECLNRLSLDLEKEI---EFQKELSMRVKA 2140
Score = 57.4 bits (137), Expect = 6e-08
Identities = 145/754 (19%), Positives = 296/754 (39%), Gaps = 79/754 (10%)
Query: 10 SKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDL--MFE 67
S + ++K IT ++ L E DLK S + + ++ +I D M
Sbjct: 901 STLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNI 960
Query: 68 EMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIG 127
+ +E L+N L+++ + TI +K+ + N K K+ G + K
Sbjct: 961 DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQD 1020
Query: 128 DDNEN---LTFKLEVNELSGK-------LDNTNEYNSNDGKKLPQGESRSYEVMGSMEET 177
+ +N LT ++ NE+ + + NE + + E ++ ++E T
Sbjct: 1021 LEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMT 1080
Query: 178 LCNI-------DDRDGNRNVHLEFTERESRKDGE-----DEFVK-EMREERKFQKLKNKE 224
+ N D+ + + + +K+GE D + E + + K Q+L+ K+
Sbjct: 1081 IENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQ 1140
Query: 225 EVLKASREEKVLMDE--GAVLTLVADLSSATLDISKQWSNVFNI---LRENDFEPKFLCE 279
+ L +EE M + + L +L + L + + + L EN E K + +
Sbjct: 1141 QQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITK 1200
Query: 280 VKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDV----LPQKEEINQGGRKYGIQEK 335
E K +LQ + F +++ ++ ++++ L KEE+ I K
Sbjct: 1201 ---------ERKVLKELQ--KSFETERDHLRGYIREIEATGLQTKEELKIAH----IHLK 1245
Query: 336 RDKTLIDSKHRA-GEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGM 394
+ ID R+ E T+ ++ L++ EE+ L ++E ++E+ E M
Sbjct: 1246 EHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETM 1305
Query: 395 EDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDA 454
+ E + E+ + S E E L E EE + T E+D+ ++
Sbjct: 1306 NELELLT--EQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEV 1363
Query: 455 KHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYL 514
KH+ ++ ET + +++S+S++E+ E T ++E + + +
Sbjct: 1364 KHD-QLKEHIRET--LAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIE 1420
Query: 515 VGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEH-KKHS 573
+ G K ++ + +E + L L S S L+ + E KH
Sbjct: 1421 IEMLGLSKRLQ-------ESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHL 1473
Query: 574 HTNLSISTGVTKLKKTEE----------KKHRTLHT-----EELTSKEADLTEETEENLR 618
T + LK+ EE +K + T E + K + +E E
Sbjct: 1474 ETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEE 1533
Query: 619 SSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTM 678
I I E++E++ LK ++++ + S+M L R+ +++I+ K+
Sbjct: 1534 QFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKE 1593
Query: 679 QMTKQIISKERQRD-IEERSRSCNIRLIGIPEKE 711
+M + + + +RD ++E ++ ++ EKE
Sbjct: 1594 EMKRVQEALQIERDQLKENTKEIVAKMKESQEKE 1627
Score = 51.2 bits (121), Expect = 4e-06
Identities = 138/743 (18%), Positives = 295/743 (39%), Gaps = 89/743 (11%)
Query: 43 LKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEF 102
L +++ + +N + + L +E++R T K +++ L K + E + E + + +
Sbjct: 491 LNQENIESELNSLRADYDNLVLDYEQLR-TEKEEMELKLKEKNDLDEFEALERKTKKDQE 549
Query: 103 QQIINLALQKTGMVGKIEGENSKIGDDNENLTFKLEV-NELSGKLDNTNEY-NSNDGKKL 160
Q+I+ +V E N + +NE L+ K+E+ E ++ EY +S + +
Sbjct: 550 MQLIHEISNLKNLVKHAEVYNQDL--ENE-LSSKVELLREKEDQIKKLQEYIDSQKLENI 606
Query: 161 PQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMREE--RKFQ 218
S S E + ++ + D + V L+ + E+ +KE +E ++
Sbjct: 607 KMDLSYSLESIEDPKQMKQTLFDAE---TVALDAKRESAFLRSENLELKEKMKELATTYK 663
Query: 219 KLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLC 278
+++N ++ ++ E K M + L +L SA +I+K S L + LC
Sbjct: 664 QMENDIQLYQSQLEAKKKMQ----VDLEKELQSAFNEITKLTS-----LIDGKVPKDLLC 714
Query: 279 EVKLAFKC-------DGEIKTFSDLQS----LRKFASQKSSVKELLKDVLPQKEE----- 322
++L K + E++ L+ L + S S V+ L K++ + EE
Sbjct: 715 NLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIIT 774
Query: 323 ----------INQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMK 372
+++ R G+ E+ KT D S F K + + ++ K
Sbjct: 775 SEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYK 834
Query: 373 N-LETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASG 431
LE E E+ L +EA + S L + E S +E +E+ ++E +
Sbjct: 835 MVLEENERMNQEIVNLSKEAQKFD-----SSLGALKTELSYKTQELQEKTREVQE-RLNE 888
Query: 432 LEEEEEQTSEQDSTFQ----GHTLVDAKHE---VEITSDGMETTFIDSVEDSESEEEEEG 484
+E+ +EQ +DST Q TL+ K + E+ + E + +++S E ++
Sbjct: 889 MEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQL 948
Query: 485 KSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQ 544
KS V T+++ + + ++ K K + +V EE T +
Sbjct: 949 KSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSK-ISEEVSRNLHMEENTGETKDE 1007
Query: 545 GTGTPCLTLCLASPSKSLEMSHDEHKKHSHT-------NLSISTGVTKLKKTEEKKHRTL 597
++ D K++ T N I +EK
Sbjct: 1008 ----------FQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQ 1057
Query: 598 HTEELTSKEADLTEETEENLRSSVINSIR------EIKEEIGNLKSSHSGVLEIENSVDD 651
E + +++ L + +EN+ ++ N E+K++ + + ++ E +
Sbjct: 1058 MLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSR 1117
Query: 652 LSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQ-RDIEERSRSCNIRLIGIPEK 710
R+ +EE++ Q++E + + + +++ +++ +IE + + +
Sbjct: 1118 TCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHM 1177
Query: 711 ESYENRAEDIIKEIIDENFAELK 733
E+ R E + + ++EN+ E+K
Sbjct: 1178 ET--ERLE--LAQKLNENYEEVK 1196
Score = 45.4 bits (106), Expect = 2e-04
Identities = 145/773 (18%), Positives = 308/773 (39%), Gaps = 86/773 (11%)
Query: 22 ITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKF-----KVLMEIQDLMFEEMRE-TLKN 75
I +M ++ ET + ++ K +S + K+ +IQ+L E + TLK
Sbjct: 1778 IAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKK 1837
Query: 76 DLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEG---ENSKIGDDNEN 132
D+ + + ++K S T + L ++ + K+ E + + +N
Sbjct: 1838 DVNETQKKVSEMEQLKKQIKDQSLT----LSKLEIENLNLAQKLHENLEEMKSVMKERDN 1893
Query: 133 L-----TFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGN 187
L T KLE ++L L T + ++L S E +ET+ + ++
Sbjct: 1894 LRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKE----HKETVDKLREKISE 1949
Query: 188 RNVHLEFTERESRKDGEDEFVKEMRE--ERKFQKLKNKEEV----LKASREEKVLMDEGA 241
+ + + +++ K +DE K+++E +++ Q L+ KE+V K + E++ A
Sbjct: 1950 KTIQISDIQKDLDKS-KDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEA 2008
Query: 242 VLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGE--IKTFSDLQSL 299
+ + ++K+ +R E L +K + K + + I T ++ +
Sbjct: 2009 QNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIAR 2068
Query: 300 RKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKT--LIDSKHRAGEITS----- 352
+ Q K LL D G+++ + R+K + + R E+
Sbjct: 2069 DRQNHQVKPEKRLLSD-----------GQQHLTESLREKCSRIKELLKRYSEMDDHYECL 2117
Query: 353 DGLSFLFLKEVKVAKPEEMK---NLETQEEEFSELEEL--DEEASGMEDDEDTSGLEEEE 407
+ LS KE++ K M+ NL + +E+L + ME L+
Sbjct: 2118 NRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVL 2177
Query: 408 EEPSGLEEEEEEEASGLEEDEASGLEEEEE-----QTSEQDSTFQGHTLVDAK------- 455
+ ++EE+ E + E D +E+++E Q +QD L D K
Sbjct: 2178 SYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDL 2237
Query: 456 HEVEITSDGMETTFIDSVEDSE---SEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFS 512
H EI D E+ F + + S +E + E + T EK + QKE
Sbjct: 2238 HIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEW-LNTRFDIEKLKNGIQKENDRI 2296
Query: 513 YLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKH 572
V + +++ +++++ E EE + S+ KSL+ +++ K+
Sbjct: 2297 CQVNNFFNNRIIA--IMNESTEFEERSATISKEW---------EQDLKSLKEKNEKLFKN 2345
Query: 573 SHT-NLSISTGVTKLKKTEEKK--HRTLHTEELTSKEADLTEETEENLRSSVINSIREIK 629
T S+++G T++ K H T +LT+++ E + + S ++ +I
Sbjct: 2346 YQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKII 2405
Query: 630 EEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKER 689
+ L+ ++ + +++ V + + ++ +E I L+D++ +K + + + K
Sbjct: 2406 KMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLV 2465
Query: 690 QRDIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDENFAELKKGSSLEIVS 742
+ D+E+ + K + E + E I ++ EN ++ ++S
Sbjct: 2466 KIDLEKMKNAKEFEKEISATKATVEYQKEVI--RLLRENLRRSQQAQDTSVIS 2516
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 59.7 bits (143), Expect = 1e-08
Identities = 34/82 (41%), Positives = 46/82 (56%)
Query: 360 LKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEE 419
L + + +E + E +EEE E EE +EE E++++ EEEEEE EEE EE
Sbjct: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEE 937
Query: 420 EASGLEEDEASGLEEEEEQTSE 441
E LEE+E EEEEE+ E
Sbjct: 938 EEGELEEEEEEEDEEEEEELEE 959
Score = 55.5 bits (132), Expect = 2e-07
Identities = 32/68 (47%), Positives = 41/68 (60%)
Query: 376 TQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEE 435
+ EEE E EE +EE E++ED EE+EEE EEEEEEE E+E LEEE
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE 945
Query: 436 EEQTSEQD 443
EE+ E++
Sbjct: 946 EEEEDEEE 953
Score = 52.4 bits (124), Expect = 2e-06
Identities = 33/80 (41%), Positives = 45/80 (56%)
Query: 361 KEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEE 420
+E + + EE + E +EEE E EE DEE E++E+ EEE EE G EEEEEE
Sbjct: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948
Query: 421 ASGLEEDEASGLEEEEEQTS 440
EE+E +E+ E T+
Sbjct: 949 EDEEEEEELEEVEDLEFGTA 968
Score = 51.6 bits (122), Expect = 3e-06
Identities = 32/75 (42%), Positives = 41/75 (54%)
Query: 361 KEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEE 420
+E + + E+ + E EEE+ E EE +EE E +E+ LEEEEEE EEEE EE
Sbjct: 900 EEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEE 959
Query: 421 ASGLEEDEASGLEEE 435
LE A G EE
Sbjct: 960 VEDLEFGTAGGEVEE 974
Score = 49.3 bits (116), Expect = 2e-05
Identities = 39/106 (36%), Positives = 51/106 (48%), Gaps = 11/106 (10%)
Query: 383 ELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQ 442
+L ++ +S E++E EEEEEE EEEEEE+ EEDE EEEEE+ E
Sbjct: 877 DLTVININSSDEEEEE-----EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEF 931
Query: 443 DSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSE----SEEEEEG 484
+ F+ E E D E ++ VED E E EEG
Sbjct: 932 EEEFEEEE--GELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEG 975
Score = 44.7 bits (104), Expect = 4e-04
Identities = 33/98 (33%), Positives = 47/98 (47%), Gaps = 6/98 (6%)
Query: 394 MEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVD 453
+E+D + +EE EEEEEEE EE+E EEEEE +++ F+ +
Sbjct: 874 LEEDLTVININSSDEEEEEEEEEEEEEEE--EEEEEEDFEEEEE---DEEEYFEEEEEEE 928
Query: 454 AKHEVEITSDGMETTFIDSVEDSESEEE-EEGKSSETG 490
+ E E + E + ED E EEE EE + E G
Sbjct: 929 EEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFG 966
Score = 38.5 bits (88), Expect = 0.027
Identities = 24/61 (39%), Positives = 33/61 (54%)
Query: 369 EEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDE 428
+E + E +EEE E EE EE G ++E+ EEEEEE +E+ E A G E+
Sbjct: 916 DEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEG 975
Query: 429 A 429
A
Sbjct: 976 A 976
Score = 32.3 bits (72), Expect = 1.9
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 359 FLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDT------SGLEEEEEEPSG 412
F +E + EE + E +EEE E+E+L+ +G E +E E P
Sbjct: 935 FEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPK 994
Query: 413 LEEEEEEEASGLEEDEASGLEEE 435
++ E E E L E E G EEE
Sbjct: 995 VQPEPEPEPGLLLEVEEPGTEEE 1017
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 59.7 bits (143), Expect = 1e-08
Identities = 133/641 (20%), Positives = 257/641 (40%), Gaps = 86/641 (13%)
Query: 149 TNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTERESRKDGED--- 205
+ E N +++ Q S+ + E N DR +R L + R GE
Sbjct: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLN-SDRLESRISELTSELTDERNTGESASQ 1310
Query: 206 ----EFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLD--ISKQ 259
E + +R E++ ++L+ + + LK E + A L A+++ D +
Sbjct: 1311 LLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGE 1370
Query: 260 WSNVFN-ILRENDFEPKFL-------CEVKLAFKCDGEIKTFSDLQ-----SLRKFASQK 306
W + +RE DF K L EV+ K E + DLQ S R K
Sbjct: 1371 WRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLE-RRLGDLQADSEESQRALQQLK 1429
Query: 307 SSVKELLKDVLPQKEEIN-QGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKV 365
+ L ++ K + Q R + +++K+ + + E + L L+ K
Sbjct: 1430 KKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKD 1489
Query: 366 AKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLE 425
E +L+ Q LEE D + +G + LE E ++ S E ++E + ++
Sbjct: 1490 MLLAEAFSLKQQ------LEEKDMDIAGFT--QKVVSLEAELQDISSQESKDEASLAKVK 1541
Query: 426 E---DEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEE 482
+ D + ++++EE+ EQ T Q L AK +E+ + M T +E S EE E
Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQ--MLEQAKLRLEMEMERMRQTHSKEME-SRDEEVE 1598
Query: 483 EGKSSETGKVKTTSLT-------EKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEE 535
E + S K+K + ++K R ++E+ GK + QV + E
Sbjct: 1599 EARQSCQKKLKQMEVQLEEEYEDKQKVLREKREL--------EGKLATLSDQVNRRDFES 1650
Query: 536 EETAVPTSQGTGTPCLTLCL-------ASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKK 588
E+ + T L ++PSK + S + + K +
Sbjct: 1651 EKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAME 1710
Query: 589 TE-EKKHRTLHTEELTSKEADLTEETE--ENLRSSVINSIREIKEEIGNLKSSHSGVL-- 643
E E H L +++ + L E+ + ++ + N + E +E++ L H +
Sbjct: 1711 VEIEDLH--LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQ 1768
Query: 644 ---------EIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKE--RQRD 692
+++ +++ + L+E++ +L+ Q+ EF + +M + K ++S++ + R+
Sbjct: 1769 ASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV-EFLEQSM-VDKSLVSRQEAKIRE 1826
Query: 693 IE-----ERSRSCNIRLIGIPEKESYENRAEDIIKEIIDEN 728
+E ER++ + + KE+ E E+ + I EN
Sbjct: 1827 LETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN 1867
Score = 40.8 bits (94), Expect = 0.005
Identities = 96/527 (18%), Positives = 203/527 (38%), Gaps = 97/527 (18%)
Query: 173 SMEETLCNIDDRDGNRNVHLEFTERESR------KDGEDEFVKE-----------MREER 215
S+E L +I ++ L +++ R KD E+E ++ +R E
Sbjct: 1518 SLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM 1577
Query: 216 KFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPK 275
+ ++++ SR+E+V E A + L + + +++ + +LRE
Sbjct: 1578 EMERMRQTHSKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKR---- 1630
Query: 276 FLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKD-VLPQKEEINQGGRKYGIQE 334
+ +G++ T SD + R F S+K K+L + L ++ K
Sbjct: 1631 ---------ELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS 1681
Query: 335 KRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGM 394
KR+ + ++ E T VK K E+ E+E+L +
Sbjct: 1682 KREIAQLKNQLEESEFTCAAA-------VKARKAMEV-----------EIEDLH-----L 1718
Query: 395 EDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDA 454
+ D+ EE+ S L+ E+ E + LEED+ E+ E +
Sbjct: 1719 QIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ----EDMNE--------------LMK 1760
Query: 455 KHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYL 514
KH+ + + + + D +++ EE K + + K +L + Q + S +
Sbjct: 1761 KHKAAVAQASRD---LAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLV 1817
Query: 515 VGDSGK-KKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHS 573
K ++L +TQ + ++ + LT + ++ + +K
Sbjct: 1818 SRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLT-----EERDQRIAAENREKEQ 1872
Query: 574 HTNLSISTGVTKLKKTEEKKHRTLHTEELTSK---EADLTEETEENLRSSVINSIREIKE 630
+ L +L+ T+E+ E S+ E ++ E+ E S+ ++ +
Sbjct: 1873 NKRLQ-----RQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFK 1927
Query: 631 EIGNLKSSHSGVLEIENSVDDLSSRMDI-----LEERIDSLEDQIEE 672
IG+L+++ +E + + D ++S D LE+R+D ++ + +
Sbjct: 1928 RIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSK 1974
Score = 33.5 bits (75), Expect = 0.87
Identities = 50/286 (17%), Positives = 115/286 (40%), Gaps = 21/286 (7%)
Query: 174 MEETLCNIDDRDGNRNVHLEFTERESRKDGE-DEFVKEMREERKFQKLKNKEEVLKASRE 232
+E+ IDD + E R R+ E ++E +E+ K+K V +ASR+
Sbjct: 1713 IEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRD 1772
Query: 233 EKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKT 292
+ D L A L A + + + + + +F + + + L + + +I+
Sbjct: 1773 LAQIND------LQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRE 1826
Query: 293 FS-----DLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKR-DKTLIDSKHR 346
+ +++ S S +KE ++ + ++++ + Q KR + L D+K
Sbjct: 1827 LETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEE 1886
Query: 347 AGEITSDGLSF--------LFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDE 398
GE+ + L+ ++ A +L+ + +L+ E+ +++E
Sbjct: 1887 MGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENE 1946
Query: 399 DTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDS 444
D E + + S LE+ + S L +++ ++ + + S
Sbjct: 1947 DLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLKSSS 1992
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 59.7 bits (143), Expect = 1e-08
Identities = 133/641 (20%), Positives = 257/641 (40%), Gaps = 86/641 (13%)
Query: 149 TNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTERESRKDGED--- 205
+ E N +++ Q S+ + E N DR +R L + R GE
Sbjct: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLN-SDRLESRISELTSELTDERNTGESASQ 1310
Query: 206 ----EFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLD--ISKQ 259
E + +R E++ ++L+ + + LK E + A L A+++ D +
Sbjct: 1311 LLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGE 1370
Query: 260 WSNVFN-ILRENDFEPKFL-------CEVKLAFKCDGEIKTFSDLQ-----SLRKFASQK 306
W + +RE DF K L EV+ K E + DLQ S R K
Sbjct: 1371 WRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLE-RRLGDLQADSEESQRALQQLK 1429
Query: 307 SSVKELLKDVLPQKEEIN-QGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKV 365
+ L ++ K + Q R + +++K+ + + E + L L+ K
Sbjct: 1430 KKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKD 1489
Query: 366 AKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLE 425
E +L+ Q LEE D + +G + LE E ++ S E ++E + ++
Sbjct: 1490 MLLAEAFSLKQQ------LEEKDMDIAGFT--QKVVSLEAELQDISSQESKDEASLAKVK 1541
Query: 426 E---DEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEE 482
+ D + ++++EE+ EQ T Q L AK +E+ + M T +E S EE E
Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQ--MLEQAKLRLEMEMERMRQTHSKEME-SRDEEVE 1598
Query: 483 EGKSSETGKVKTTSLT-------EKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEE 535
E + S K+K + ++K R ++E+ GK + QV + E
Sbjct: 1599 EARQSCQKKLKQMEVQLEEEYEDKQKVLREKREL--------EGKLATLSDQVNRRDFES 1650
Query: 536 EETAVPTSQGTGTPCLTLCL-------ASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKK 588
E+ + T L ++PSK + S + + K +
Sbjct: 1651 EKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAME 1710
Query: 589 TE-EKKHRTLHTEELTSKEADLTEETE--ENLRSSVINSIREIKEEIGNLKSSHSGVL-- 643
E E H L +++ + L E+ + ++ + N + E +E++ L H +
Sbjct: 1711 VEIEDLH--LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQ 1768
Query: 644 ---------EIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKE--RQRD 692
+++ +++ + L+E++ +L+ Q+ EF + +M + K ++S++ + R+
Sbjct: 1769 ASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV-EFLEQSM-VDKSLVSRQEAKIRE 1826
Query: 693 IE-----ERSRSCNIRLIGIPEKESYENRAEDIIKEIIDEN 728
+E ER++ + + KE+ E E+ + I EN
Sbjct: 1827 LETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN 1867
Score = 40.8 bits (94), Expect = 0.005
Identities = 99/544 (18%), Positives = 211/544 (38%), Gaps = 97/544 (17%)
Query: 173 SMEETLCNIDDRDGNRNVHLEFTERESR------KDGEDEFVKE-----------MREER 215
S+E L +I ++ L +++ R KD E+E ++ +R E
Sbjct: 1518 SLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM 1577
Query: 216 KFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPK 275
+ ++++ SR+E+V E A + L + + +++ + +LRE
Sbjct: 1578 EMERMRQTHSKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKR---- 1630
Query: 276 FLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKD-VLPQKEEINQGGRKYGIQE 334
+ +G++ T SD + R F S+K K+L + L ++ K
Sbjct: 1631 ---------ELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS 1681
Query: 335 KRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGM 394
KR+ + ++ E T VK K E+ E+E+L +
Sbjct: 1682 KREIAQLKNQLEESEFTCAAA-------VKARKAMEV-----------EIEDLH-----L 1718
Query: 395 EDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDA 454
+ D+ EE+ S L+ E+ E + LEED+ E+ E +
Sbjct: 1719 QIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ----EDMNE--------------LMK 1760
Query: 455 KHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYL 514
KH+ + + + + D +++ EE K + + K +L + Q + S +
Sbjct: 1761 KHKAAVAQASRD---LAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLV 1817
Query: 515 VGDSGK-KKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHS 573
K ++L +TQ + ++ + LT + ++ + +K
Sbjct: 1818 SRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLT-----EERDQRIAAENREKEQ 1872
Query: 574 HTNLSISTGVTKLKKTEEKKHRTLHTEELTSK---EADLTEETEENLRSSVINSIREIKE 630
+ L +L+ T+E+ E S+ E ++ E+ E S+ ++ +
Sbjct: 1873 NKRLQ-----RQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFK 1927
Query: 631 EIGNLKSSHSGVLEIENSVDDLSSRMDIL---EERIDSLE--DQIEEFSKDTMQMTKQII 685
IG+L+++ +E + + D ++S D++ ++R + LE ++ +D + K +
Sbjct: 1928 RIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSWL 1987
Query: 686 SKER 689
SK +
Sbjct: 1988 SKNK 1991
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,196,763
Number of Sequences: 37866
Number of extensions: 1583099
Number of successful extensions: 36051
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 490
Number of HSP's successfully gapped in prelim test: 1307
Number of HSP's that attempted gapping in prelim test: 11512
Number of HSP's gapped (non-prelim): 10004
length of query: 865
length of database: 18,247,518
effective HSP length: 111
effective length of query: 754
effective length of database: 14,044,392
effective search space: 10589471568
effective search space used: 10589471568
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.