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Search of human proteins with 157649069
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157649069 ATPase, aminophospholipid transporter (APLT),
class I, type 8A, member 1 isoform b [Homo sapiens]
(1149 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 2297 0.0
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 2264 0.0
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 1597 0.0
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 845 0.0
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 840 0.0
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 825 0.0
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 688 0.0
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 683 0.0
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 682 0.0
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 663 0.0
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 662 0.0
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 662 0.0
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 467 e-131
gi|41327760 ATPase, class II, type 9B [Homo sapiens] 439 e-123
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 418 e-116
gi|149944474 ATPase, class V, type 10B [Homo sapiens] 406 e-113
gi|14424433 ATPase, class V, type 10A [Homo sapiens] 402 e-112
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 277 5e-74
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 92 2e-18
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 92 2e-18
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 90 1e-17
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 89 2e-17
gi|66932949 ATPase type 13A4 [Homo sapiens] 89 2e-17
gi|148839292 ATPase type 13A3 [Homo sapiens] 88 4e-17
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 87 7e-17
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 87 7e-17
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 80 1e-14
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 74 1e-12
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 74 1e-12
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 73 1e-12
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 2297 bits (5952), Expect = 0.0
Identities = 1149/1149 (100%), Positives = 1149/1149 (100%)
Query: 1 MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN 60
MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN
Sbjct: 1 MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN 60
Query: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED
Sbjct: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
Query: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAM 180
IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAM
Sbjct: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAM 180
Query: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH
Sbjct: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
Query: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI
Sbjct: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
Query: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL
Sbjct: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
Query: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ
Sbjct: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
Query: 421 FKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPERE 480
FKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPERE
Sbjct: 421 FKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPERE 480
Query: 481 GDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKR 540
GDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKR
Sbjct: 481 GDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKR 540
Query: 541 MSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEIS 600
MSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEIS
Sbjct: 541 MSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEIS 600
Query: 601 ESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLM 660
ESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLM
Sbjct: 601 ESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLM 660
Query: 661 KADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALR 720
KADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALR
Sbjct: 661 KADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALR 720
Query: 721 KENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVV 780
KENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVV
Sbjct: 721 KENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVV 780
Query: 781 TLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRV 840
TLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRV
Sbjct: 781 TLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRV 840
Query: 841 SKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSC 900
SKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSC
Sbjct: 841 SKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSC 900
Query: 901 RKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTS 960
RKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTS
Sbjct: 901 RKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTS 960
Query: 961 DYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAIPMA 1020
DYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAIPMA
Sbjct: 961 DYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAIPMA 1020
Query: 1021 PDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAKSQDPG 1080
PDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAKSQDPG
Sbjct: 1021 PDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAKSQDPG 1080
Query: 1081 AVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQDENGIVSQSEVIRAYD 1140
AVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQDENGIVSQSEVIRAYD
Sbjct: 1081 AVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQDENGIVSQSEVIRAYD 1140
Query: 1141 TTKQRPDEW 1149
TTKQRPDEW
Sbjct: 1141 TTKQRPDEW 1149
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 2264 bits (5867), Expect = 0.0
Identities = 1137/1164 (97%), Positives = 1142/1164 (98%), Gaps = 15/1164 (1%)
Query: 1 MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN 60
MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN
Sbjct: 1 MPTMRRTVSEIRSRAEGYEKTDDVSEKTSLADQEEVRTIFINQPQLTKFCNNHVSTAKYN 60
Query: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED
Sbjct: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
Query: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAM 180
IKRHKADNAVNKKQTQVLRNGAWEIVHWEKV VG+IV + E++PAD + LSSSEPQAM
Sbjct: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLPADLISLSSSEPQAM 180
Query: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH
Sbjct: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
Query: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI
Sbjct: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
Query: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL
Sbjct: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
Query: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ
Sbjct: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
Query: 421 FKKCTIAGVAYG---------------QNSQFGDEKTFSDSSLLENLQNNHPTAPIICEF 465
FKKCTIAGVAYG QNSQFGDEKTFSDSSLLENLQNNHPTAPIICEF
Sbjct: 421 FKKCTIAGVAYGHVPEPEDYGCSPDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEF 480
Query: 466 LTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEER 525
LTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEER
Sbjct: 481 LTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEER 540
Query: 526 YELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFA 585
YELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFA
Sbjct: 541 YELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFA 600
Query: 586 TEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIE 645
TEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIE
Sbjct: 601 TEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIE 660
Query: 646 DKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTR 705
DKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTR
Sbjct: 661 DKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTR 720
Query: 706 ETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ 765
ETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ
Sbjct: 721 ETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ 780
Query: 766 KSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYL 825
KSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYL
Sbjct: 781 KSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYL 840
Query: 826 KNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMF 885
KNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMF
Sbjct: 841 KNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMF 900
Query: 886 TAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPL 945
TAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPL
Sbjct: 901 TAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPL 960
Query: 946 KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV 1005
KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV
Sbjct: 961 KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV 1020
Query: 1006 FFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTL 1065
FFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTL
Sbjct: 1021 FFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTL 1080
Query: 1066 VDEVQELEAKSQDPGAVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQD 1125
VDEVQELEAKSQDPGAVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQD
Sbjct: 1081 VDEVQELEAKSQDPGAVVLGKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGYAFSQD 1140
Query: 1126 ENGIVSQSEVIRAYDTTKQRPDEW 1149
ENGIVSQSEVIRAYDTTKQRPDEW
Sbjct: 1141 ENGIVSQSEVIRAYDTTKQRPDEW 1164
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 1597 bits (4136), Expect = 0.0
Identities = 782/1165 (67%), Positives = 945/1165 (81%), Gaps = 24/1165 (2%)
Query: 4 MRRTVSEIRSRAEGYEKTDD-VSEKTSLADQEEV--RTIFINQPQLTKFCNNHVSTAKYN 60
+R +V +RS GY+K +D +S TS+ DQ E RTI++NQP L KF +N +STAKY+
Sbjct: 21 IRSSVGPVRSSL-GYKKAEDEMSRATSVGDQLEAPARTIYLNQPHLNKFRDNQISTAKYS 79
Query: 61 IITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIED 120
++TFLPRFLY Q RRAAN+FFLFIALLQQIPDVSPTGRYTTLVPL+ IL +A IKEI+ED
Sbjct: 80 VLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVED 139
Query: 121 IKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAM 180
KRHKADNAVNKK+T VLRNG W + W++V VGDIV + +Y+PAD VLLSSSEPQAM
Sbjct: 140 FKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAM 199
Query: 181 CYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGH 240
CY+ET+NLDGETNLKIRQGL T+D++ + LM++SG IECE PNRHLYDF GN+ LDG
Sbjct: 200 CYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGK 259
Query: 241 GTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILI 300
V LG DQILLRG QLRNTQWV GIVVYTGHDTKLMQNST PLK SNVE++TNVQIL+
Sbjct: 260 SLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILV 319
Query: 301 LFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLL 360
LF IL+ M+LV S G+ WNR H K+WY+ + NFG N LTFIIL+NNLIPISLL
Sbjct: 320 LFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYNLLTFIILYNNLIPISLL 379
Query: 361 VTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQ 420
VTLEVVK+TQA FINWD DM+Y DT AMARTSNLNEELGQVKY+FSDKTGTLTCN+M
Sbjct: 380 VTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMN 439
Query: 421 FKKCTIAGVAYGQNSQFGDEKT----------------FSDSSLLENLQNNHPTAPIICE 464
FKKC+IAGV YG + E + F D LL+N+++ HPTAP I E
Sbjct: 440 FKKCSIAGVTYGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQE 499
Query: 465 FLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEE 524
FLT++AVCHT VPE++GD IIYQA+SPDE ALV+ AK+L FVFT RTP SVII+++GQE+
Sbjct: 500 FLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGFVFTARTPFSVIIEAMGQEQ 559
Query: 525 RYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQF 584
+ +LNVLEF+S RKRMSVIVRTPSG+LRLYCKGAD VI++RL++ SKY E TL HLE F
Sbjct: 560 TFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKDSKYMEETLCHLEYF 619
Query: 585 ATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAI 644
ATEGLRTLC A A++SE++++EW VYQ AST +++R +LEE YE+IEKNL LLGATAI
Sbjct: 620 ATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAI 679
Query: 645 EDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGT 704
ED+LQ VPETI TL+KA+IKIW+LTGDKQETAINIG+SC+L+ +NM +I++ E SLD T
Sbjct: 680 EDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDAT 739
Query: 705 RETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPL 764
R +++HCT LG+ L KEND ALIIDG TLKYAL+F VR+ FLDLALSCKAVICCRVSPL
Sbjct: 740 RAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPL 799
Query: 765 QKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKY 824
QKSE+V++VKK+VK +TLAIGDGANDV MIQTAHVGVGISGNEG+QA N+SDY+IAQF Y
Sbjct: 800 QKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSY 859
Query: 825 LKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVM 884
L+ LL++HGAW+YNRV+KCILYCFYKN+VLYIIE+WFAFVNGFSGQILFERWCIGLYNV+
Sbjct: 860 LEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVI 919
Query: 885 FTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFP 944
FTA+PP TLGIFERSC +E+ML++P+LYK +QN FNTKVFW HC+N L HS+ILFWFP
Sbjct: 920 FTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWFP 979
Query: 945 LKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV 1004
+KAL++ T +G +DYL +GN VYT+VV+TVCLKAGLET+ WT FSH+A+WGS+ W+
Sbjct: 980 MKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLTWL 1039
Query: 1005 VFFGIYSSLWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKT 1064
VFFGIYS++WP IP+APDM G+A M+ SS FW+GL +P A L+ DV ++ K T KT
Sbjct: 1040 VFFGIYSTIWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDVAWRAAKHTCKKT 1099
Query: 1065 LVDEVQELEAKSQDPGAVVL----GKSLTERAQLLKNVFKKNHVNLYRSESLQQNLLHGY 1120
L++EVQELE KS+ G VL GK L ER +L+K + +K L+R SLQQ + HGY
Sbjct: 1100 LLEEVQELETKSRVLGKAVLRDSNGKRLNERDRLIKRLGRKTPPTLFRGSSLQQGVPHGY 1159
Query: 1121 AFSQDENGIVSQSEVIRAYDTTKQR 1145
AFSQ+E+G VSQ EVIRAYDTTK++
Sbjct: 1160 AFSQEEHGAVSQEEVIRAYDTTKKK 1184
>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
Length = 1223
Score = 845 bits (2183), Expect = 0.0
Identities = 447/1078 (41%), Positives = 662/1078 (61%), Gaps = 60/1078 (5%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ +N + T+KYNI+TFLP L+ QF+ AN++FLF+ +LQ IP +S +TT+VPL+
Sbjct: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPA 167
+L + A+K+ +D RHK+DN VN +Q+QVL NG + W V VGDI+ ++ +++ A
Sbjct: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
Query: 168 DTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227
D +LLSSSEP +CYIET+ LDGETN+K+RQ +P TS++ D+ L + G + CE PN
Sbjct: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
Query: 228 LYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKL 287
L F G + PL +LLRG LRNT+W G+V++ G DTKLMQNS K
Sbjct: 241 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 299
Query: 288 SNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-----DWYLNLNYGGASNFGL 342
++++R+ N +L +F L+ M ++ ++G+AIW + W ++ S F L
Sbjct: 300 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGF-L 358
Query: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
+F ++II+ N ++PISL V++EV++ +YFINWD M T A ART+ LNEELGQ
Sbjct: 359 SFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQ 418
Query: 403 VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQ-------NSQFGDEKT------------- 442
V+YIFSDKTGTLT N+M F KC+I G +YG ++ G+
Sbjct: 419 VEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKK 478
Query: 443 --FSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGD-KIIYQAASPDEGALVRA 499
F D SLLE ++ P EF ++++CHT + E + + ++ Y+A SPDEGALV A
Sbjct: 479 FLFWDPSLLEAVKIGDPHTH---EFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTA 535
Query: 500 AKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGA 559
A+ FVF RTP ++ + +G Y+LL +L+F + RKRMSVIVR P GK+RLYCKGA
Sbjct: 536 ARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGA 595
Query: 560 DTVIYDRLAE-TSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSV 618
DT++ DRL T + T+ HL ++A EGLRTL A ++ E ++EW +AS +
Sbjct: 596 DTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQ 655
Query: 619 QNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAI 678
+R +L YE +E N+ LLGATAIEDKLQ VPETI L A+IKIW+LTGDKQETA+
Sbjct: 656 DSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAV 715
Query: 679 NIGHSCKLLKKNMGMIVINEG--------SLDGTRETLSRHCTTLGDALRKEN------- 723
NIG+SCK+L +M + I G L RE + ++G+ ++
Sbjct: 716 NIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKL 775
Query: 724 ---------DFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVK 774
++AL+I+G +L +AL + FL+ A +CKAVICCRV+PLQK++VVE+VK
Sbjct: 776 TSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVK 835
Query: 775 KQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGA 834
K K VTLAIGDGANDVSMI+TAH+GVGISG EG+QA +SDYS +QFK+L+ LL++HG
Sbjct: 836 KYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGR 895
Query: 835 WNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLG 894
W+Y R+ K + Y FYKN ++ WF F GFS Q +++++ I LYN+++T++P L +G
Sbjct: 896 WSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMG 955
Query: 895 IFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAF 954
+F++ ++ ++YP+LY+ Q L FN + F++ G++ SV++F+ P T
Sbjct: 956 VFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRD 1015
Query: 955 GNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALW-VVFFGIYSS- 1012
+ +DY V T +VI V ++ GL+T YWT +H IWGS+A++ + F ++S+
Sbjct: 1016 DGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNG 1075
Query: 1013 LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQ 1070
L+ P G A + W+ ++ V ++ V ++ ++ L D V+
Sbjct: 1076 LFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVR 1133
>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
Length = 1192
Score = 840 bits (2170), Expect = 0.0
Identities = 453/1094 (41%), Positives = 685/1094 (62%), Gaps = 65/1094 (5%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ +N + T+KYNI+TFLP L+ QF+R AN++FL + +LQ IP++S +TT+VPL+
Sbjct: 27 QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPA 167
++ + A+K+ +D RHK+DN VN +Q++VL N + W V VGDI+ ++ +++ A
Sbjct: 87 VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
Query: 168 DTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDI-KDVDSLMRISGRIECESPNR 226
D +LLSSSEP +CY+ET+ LDGETNLK+R L TS++ D+ L G + CE PN
Sbjct: 147 DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
Query: 227 HLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLK 286
L F+G + L ++I+LRG LRNT W G+V++ G DTKLMQNS K
Sbjct: 207 KLDKFMGILSWKD-SKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFK 265
Query: 287 LSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-DWYLNLNYGGASNFGLNFL 345
++++R+ N +L +F LI + ++ ++G++IW + + +L N G S+ FL
Sbjct: 266 RTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGEKSSVFSGFL 325
Query: 346 TF---IILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
TF II+ N ++PISL V++EV++ +YFINWD M+Y A+ART+ LNEELGQ
Sbjct: 326 TFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNEELGQ 385
Query: 403 VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKT-------------------- 442
++YIFSDKTGTLT N+M FK+C+I G YG+ D+KT
Sbjct: 386 IEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVKSQADRE 445
Query: 443 --FSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREG-DKIIYQAASPDEGALVRA 499
F D L+E+++ P + EFL ++A+CHT + E ++IYQ SPDEGALV A
Sbjct: 446 FQFFDHHLMESIKMGDPK---VHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALVTA 502
Query: 500 AKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGA 559
A+ F+F RTP+++ I+ LG Y+LL L+F + RKRMSVIVR P G+++LY KGA
Sbjct: 503 ARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSKGA 562
Query: 560 DTVIYDRLAETSKYK-EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSV 618
DT+++++L +++ +T HL +FA EGLRTL A ++ + F+EW + + A+ +
Sbjct: 563 DTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAAT 622
Query: 619 QNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAI 678
+ R ++ YE IE++L LLGATA+EDKLQ+ V ET+ +L A+IKIW+LTGDKQETAI
Sbjct: 623 EERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAI 682
Query: 679 NIGHSCKLLKKNMG-MIVINEGSLDGTRETLSRHCTTLG--------------------- 716
NIG++C +L +M + VI + RE L + L
Sbjct: 683 NIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQLEL 742
Query: 717 DALRKEN---DFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV 773
D++ +E D+ALII+G +L +AL V+ L+LA CK VICCRV+PLQK++VVE+V
Sbjct: 743 DSIVEETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELV 802
Query: 774 KKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHG 833
KK VTLAIGDGANDVSMI++AH+GVGISG EGLQA +SDYS AQF+YL+ LL++HG
Sbjct: 803 KKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHG 862
Query: 834 AWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTL 893
W+Y R+ K + Y FYKN ++ WF F GFS Q ++++W I L+N+++T++P L +
Sbjct: 863 RWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAM 922
Query: 894 GIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTA 953
GIF++ +N + P+LYK Q L FN + F++ L+G++ S++LF+ P A Y A
Sbjct: 923 GIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAF-YNVA 981
Query: 954 FGNGK-TSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV-VFFGIYS 1011
+G+ +DY + T +VI V ++ L+TSYWT+ +H+ IWGSIA++ + F ++S
Sbjct: 982 GEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHS 1041
Query: 1012 S-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEV- 1069
+ ++ P G A + W+ +L VAS++ V ++ +K + TL D++
Sbjct: 1042 NGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQIR 1101
Query: 1070 --QELEAKSQDPGA 1081
Q+ + K++ P +
Sbjct: 1102 RWQKAQKKARPPSS 1115
>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
Length = 1251
Score = 825 bits (2131), Expect = 0.0
Identities = 454/1094 (41%), Positives = 648/1094 (59%), Gaps = 72/1094 (6%)
Query: 47 TKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLL 106
+K+ NN + T KYN TF+P L+ QF+RAAN +FL + +LQ +P +S YTTLVPLL
Sbjct: 90 SKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLL 149
Query: 107 FILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIP 166
+L V AIK++++D+ RHK D +N + +V+++G +++ W+++ VGD++ +K +++P
Sbjct: 150 VVLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVP 209
Query: 167 ADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSD-IKDVDSLMRISGRIECESPN 225
AD +LLSSSEP ++CY+ET+ LDGETNLK + L T ++ D+L G IECE PN
Sbjct: 210 ADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPN 269
Query: 226 RHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPL 285
L F G + + + PL AD+ILLRG +RNT + HG+V++ G DTK+M+NS
Sbjct: 270 NRLDKFTGTL-FWRNTSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKTRF 328
Query: 286 KLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFG--LN 343
K + ++ + N + +F +LI +S ++G A W + WYL ++ L
Sbjct: 329 KRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYRGFLI 388
Query: 344 FLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQV 403
F +II+ N ++PISL V++EV++ Q++FINWDL M+Y DT A ART+ LNE+LGQ+
Sbjct: 389 FWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQI 448
Query: 404 KYIFSDKTGTLTCNVMQFKKCTIAGVAYGQN------------------SQFGDEK-TFS 444
YIFSDKTGTLT N+M FKKC I G YG + + + D K F
Sbjct: 449 HYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYADGKLAFY 508
Query: 445 DSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLN 504
D L+E +Q+ P + +F ++AVCHT + +R ++ YQAASPDEGALV AA+
Sbjct: 509 DHYLIEQIQSGKE--PEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAARNFG 566
Query: 505 FVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIY 564
F F RT +++ I LG E Y +L +L+F S RKRMS+IVRTP G ++LYCKGADTVIY
Sbjct: 567 FAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGADTVIY 626
Query: 565 DRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLK 624
+RL + K+ T L+ FA E LRTLC EI E +F EW + AS + NR
Sbjct: 627 ERLHRMNPTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEA 686
Query: 625 LEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDK----------- 673
L++ YE IEK+L LLGATAIEDKLQD VPETI L KADIKIW+LTGDK
Sbjct: 687 LDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFAC 746
Query: 674 ----QETAINIGHSCKLL-------KKNMGMIV------INEGSLD--GTR--------- 705
++T I G L ++N G + + E G R
Sbjct: 747 ELLTEDTTICYGEDINSLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNRALIITGSWL 806
Query: 706 -ETLSRHCTTLGDAL-----RKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICC 759
E L T L R E + + K A ++ F+DLA C AVICC
Sbjct: 807 NEILLEKKTKRNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVICC 866
Query: 760 RVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSI 819
RV+P QK+ VV++VK+ K +TLAIGDGANDV+MI+TAH+GVGISG EG+QA SSDYS
Sbjct: 867 RVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSF 926
Query: 820 AQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIG 879
AQF+YL+ LL++HG W+Y R+ K + Y FYKN ++ W++F NG+S Q +E W I
Sbjct: 927 AQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFIT 986
Query: 880 LYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVI 939
LYNV++T++P L +G+ ++ + L++P LY Q L FN K F+V L+G+ S+I
Sbjct: 987 LYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMI 1046
Query: 940 LFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGS 999
LF+ PL A SDY + + +VITV + GL+TSYWT+ + +I+GS
Sbjct: 1047 LFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGS 1106
Query: 1000 IALWV-VFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVI 1057
IAL+ + F +S+ + P A +G A+ W+ ++ LL V + +
Sbjct: 1107 IALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFL 1166
Query: 1058 KRTAFKTLVDEVQE 1071
T + + D++Q+
Sbjct: 1167 SMTIWPSESDKIQK 1180
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 688 bits (1776), Expect = 0.0
Identities = 420/1110 (37%), Positives = 632/1110 (56%), Gaps = 79/1110 (7%)
Query: 33 QEEVRTIFINQ---------PQLTKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLF 83
Q + RTI++ PQ KF +N + ++KY + F+P+ L+ QFRR AN +FL
Sbjct: 16 QSDTRTIYVANRFPQNGLYTPQ--KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLI 73
Query: 84 IALLQQIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAW 143
I L+Q + D +PT T+ +PL F++ V AIK+ ED RH +DN VN V+R+G
Sbjct: 74 IFLVQLMID-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGL 132
Query: 144 EIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPAT 203
+ + VGDIV I E PAD VLLSS C++ T++LDGETNLK +P T
Sbjct: 133 VKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPET 192
Query: 204 SDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTV---PLGADQILLRGAQLRNT 260
+ ++ V +L + IEC+ P LY F+G + + PLG + +LLRGA+L+NT
Sbjct: 193 ALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNT 252
Query: 261 QWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWN 320
+ + G+ VYTG +TK+ N S K S VE+ N ++I ILI+ +++ ++ W
Sbjct: 253 KEIFGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQ 312
Query: 321 RRHSGKD-WYLNL-----NYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFI 374
+ WY N F +FL F++L+N +IPISL VT+E+ KF ++FI
Sbjct: 313 AEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFI 372
Query: 375 NWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQ- 433
WDLD+++E +D A TS+LNEELGQV+Y+F+DKTGTLT N MQF++C+I G+ Y +
Sbjct: 373 GWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEI 432
Query: 434 -----------NSQFGDEKTFSDSSLLENLQN-----NHPTAP-----IICE---FLTMM 469
+S G+ S S L NL + + T+P +I E F +
Sbjct: 433 NGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAV 492
Query: 470 AVCHTAV-----PEREGD----------KIIYQAASPDEGALVRAAKQLNFVFTGRTPDS 514
++CHT + GD ++ Y A+SPDE ALV AA ++ VF G + ++
Sbjct: 493 SLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEET 552
Query: 515 VIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYK 574
+ + +LG+ ERY+LL++LEF S R+RMSVIV+ PSG+ L+ KGA++ I + K
Sbjct: 553 MEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIEK 612
Query: 575 EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEK 634
T H+++FA +GLRTLC A + + +++E A T++Q R KL ++ IEK
Sbjct: 613 --TRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEK 670
Query: 635 NLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMI 694
+L LLGATA+ED+LQD+V ETIE L A IK+W+LTGDK ETA+++ SC + M ++
Sbjct: 671 DLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNIL 730
Query: 695 -VINEGSLDGTRETLSRHCTTLGDALRKEN--DFALIIDGKTLKYALTFGVRQYFLDLAL 751
+IN+ S E L + L + +++ L++DG +L AL + F+++
Sbjct: 731 ELINQKSDSECAEQLRQ----LARRITEDHVIQHGLVVDGTSLSLALREH-EKLFMEVCR 785
Query: 752 SCKAVICCRVSPLQKSEVVEMVK-KQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQ 810
+C AV+CCR++PLQK++V+ ++K K +TLA+GDGANDVSMIQ AHVG+GI G EG Q
Sbjct: 786 NCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQ 845
Query: 811 AANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQ 870
AA +SDY+IA+FK+L LL +HG + Y R++ + Y FYKN+ + + F FS Q
Sbjct: 846 AARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQ 905
Query: 871 ILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYK--TSQNALDFNTKVFWV 928
L++ + LYN+ FT++P L + E+ + P LY+ + L T ++W
Sbjct: 906 TLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWT 965
Query: 929 HCLNGLFHSVILFWFPLKALQYGTA-FGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSY 987
+ G H+ I F+ + T+ GNG+ G V+T +VITV +K LET +
Sbjct: 966 --ILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHF 1023
Query: 988 WTWFSHIAIWGSIALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVA 1046
WTW +H+ WGSI + VF Y LWP + + +M L SSG W ++ + V
Sbjct: 1024 WTWINHLVTWGSIIFYFVFSLFYGGILWPFLG-SQNMYFVFIQLLSSGSAWFAIILMVVT 1082
Query: 1047 SLLLDVVYKVIKRTAFKTLVDEVQELEAKS 1076
L LD++ KV R T ++ Q E +
Sbjct: 1083 CLFLDIIKKVFDRHLHPTSTEKAQLTETNA 1112
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 683 bits (1763), Expect = 0.0
Identities = 408/1083 (37%), Positives = 616/1083 (56%), Gaps = 61/1083 (5%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ +N + ++KY F+P+ L+ QFRR AN +FL I L+Q I D +PT T+ +PL F
Sbjct: 44 RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIID-TPTSPVTSGLPLFF 102
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPA 167
++ V AIK+ ED RHKADNA+N+ +++G K+ VGDIV++K E P
Sbjct: 103 VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162
Query: 168 DTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227
D + LSS+ C++ T++LDGE++ K + T + + + IECE P
Sbjct: 163 DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPD 222
Query: 228 LYDFVGNIR----LDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSP 283
LY FVG I L+ PLG++ +LLRGA L+NT+ + G+ +YTG +TK+ N S
Sbjct: 223 LYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSK 282
Query: 284 PLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGL- 342
K S VE+ N +++ CILI+ +L+ +V +W + + N L
Sbjct: 283 SQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLF 342
Query: 343 -----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLN 397
+FL F++LFN +IP+S+ VT+E+ KF +YFI WD DM E T + TS+LN
Sbjct: 343 LKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLN 402
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQ----NSQFGDEKTFSDSSLLENLQ 453
EELGQV+YIF+DKTGTLT N M+FK+C I G Y N Q E + D
Sbjct: 403 EELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPHVICNGQVLPESSGIDMIDSSPSV 462
Query: 454 NNHPTAPIICEFLTMMAVCHTAVPERE------------GDKIIYQAASPDEGALVRAAK 501
N + F + +CHT + + G +Y ++SPDE ALV +
Sbjct: 463 NGREREEL---FFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQ 519
Query: 502 QLNFVFTGRTPDSV--IIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGA 559
+L F + R D+ I++ ER+ELL +L F S R+RMSVIV++ +G++ L+CKGA
Sbjct: 520 RLGFTYL-RLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGA 578
Query: 560 DTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQ 619
D+ I+ R+ E K +I + +E+ A EGLRTLC A + + +++ + Q A ++Q
Sbjct: 579 DSSIFPRVIE-GKVDQIRAR-VERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQ 636
Query: 620 NRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAIN 679
+R KL E+YE IEK+L LLGATA+ED+LQ++ +TIE L KA IK+W+LTGDK ETA
Sbjct: 637 DREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAA 696
Query: 680 IGHSCKLLKKNMGMIV-----INEGSLDGTRETLSRHCTTLGDALRKEN---------DF 725
++CKL ++N ++ I E SL LS+ +L ++N D+
Sbjct: 697 TCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDY 756
Query: 726 ALIIDGKTLKYAL-------TFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVK-KQV 777
LIIDG L + + R+ FL++ SC AV+CCR++PLQK+++V+++K +
Sbjct: 757 GLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKE 816
Query: 778 KVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNY 837
+TLAIGDGANDVSMI AHVG+G+ G EG QAA +SDY+I +FK+LK +L++HG + Y
Sbjct: 817 HPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYY 876
Query: 838 NRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFE 897
R+S+ + Y FYKN+ + + F GFS Q L++ + LYN+ FT++P L + E
Sbjct: 877 IRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLME 936
Query: 898 RSCRKENMLKYPELYK-TSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGN 956
+ + + + P LY+ ++NAL +VF L GLF +++ F+ + T N
Sbjct: 937 QHVGIDVLKRDPTLYRDVAKNAL-LRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSN 995
Query: 957 GKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSS-LWP 1015
G+ G V+T +V TV LK L+T YWTW +H IWGS+ +VVF ++ +WP
Sbjct: 996 GQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWP 1055
Query: 1016 AIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAK 1075
+ M + SSG W+ ++ + SLL DV+ KV+ R + T + VQ A+
Sbjct: 1056 FLNY-QRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERVQNGCAQ 1114
Query: 1076 SQD 1078
+D
Sbjct: 1115 PRD 1117
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 682 bits (1760), Expect = 0.0
Identities = 406/1075 (37%), Positives = 612/1075 (56%), Gaps = 61/1075 (5%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ +N + ++KY F+P+ L+ QFRR AN +FL I L+Q I D +PT T+ +PL F
Sbjct: 44 RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIID-TPTSPVTSGLPLFF 102
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPA 167
++ V AIK+ ED RHKADNA+N+ +++G K+ VGDIV++K E P
Sbjct: 103 VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162
Query: 168 DTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227
D + LSS+ C++ T++LDGE++ K + T + + + IECE P
Sbjct: 163 DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEEDIGGLHATIECEQPQPD 222
Query: 228 LYDFVGNIR----LDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSP 283
LY FVG I L+ PLG++ +LLRGA L+NT+ + G+ +YTG +TK+ N S
Sbjct: 223 LYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQSK 282
Query: 284 PLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGL- 342
K S VE+ N +++ CILI+ +L+ +V +W + + N L
Sbjct: 283 SQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNLF 342
Query: 343 -----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLN 397
+FL F++LFN +IP+S+ VT+E+ KF +YFI WD DM E T + TS+LN
Sbjct: 343 LKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDLN 402
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQ----NSQFGDEKTFSDSSLLENLQ 453
EELGQV+YIF+DKTGTLT N M+FK+C I G Y N Q E + D
Sbjct: 403 EELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPHVICNGQVLPESSGIDMIDSSPSV 462
Query: 454 NNHPTAPIICEFLTMMAVCHTAVPERE------------GDKIIYQAASPDEGALVRAAK 501
N + F + +CHT + + G +Y ++SPDE ALV +
Sbjct: 463 NGREREEL---FFRALCLCHTVQVKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQ 519
Query: 502 QLNFVFTGRTPDSV--IIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGA 559
+L F + R D+ I++ ER+ELL +L F S R+RMSVIV++ +G++ L+CKGA
Sbjct: 520 RLGFTYL-RLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVIVKSATGEIYLFCKGA 578
Query: 560 DTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQ 619
D+ I+ R+ E K +I + +E+ A EGLRTLC A + + +++ + Q A ++Q
Sbjct: 579 DSSIFPRVIE-GKVDQIRAR-VERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQ 636
Query: 620 NRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAIN 679
+R KL E+YE IEK+L LLGATA+ED+LQ++ +TIE L KA IK+W+LTGDK ETA
Sbjct: 637 DREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAA 696
Query: 680 IGHSCKLLKKNMGMIV-----INEGSLDGTRETLSRHCTTLGDALRKEN---------DF 725
++CKL ++N ++ I E SL LS+ +L ++N D+
Sbjct: 697 TCYACKLFRRNTQLLELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDY 756
Query: 726 ALIIDGKTLKYAL-------TFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVK-KQV 777
LIIDG L + + R+ FL++ SC AV+CCR++PLQK+++V+++K +
Sbjct: 757 GLIIDGAALSLIMKPREDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKE 816
Query: 778 KVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNY 837
+TLAIGDGANDVSMI AHVG+G+ G EG QAA +SDY+I +FK+LK +L++HG + Y
Sbjct: 817 HPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYY 876
Query: 838 NRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFE 897
R+S+ + Y FYKN+ + + F GFS Q L++ + LYN+ FT++P L + E
Sbjct: 877 IRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLME 936
Query: 898 RSCRKENMLKYPELYK-TSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGN 956
+ + + + P LY+ ++NAL +VF L GLF +++ F+ + T N
Sbjct: 937 QHVGIDVLKRDPTLYRDVAKNAL-LRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSN 995
Query: 957 GKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSS-LWP 1015
G+ G V+T +V TV LK L+T YWTW +H IWGS+ +VVF ++ +WP
Sbjct: 996 GQIFGNWTFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWP 1055
Query: 1016 AIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQ 1070
+ M + SSG W+ ++ + SLL DV+ KV+ R + T + VQ
Sbjct: 1056 FLNY-QRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERVQ 1109
>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
Length = 1300
Score = 663 bits (1711), Expect = 0.0
Identities = 393/1112 (35%), Positives = 618/1112 (55%), Gaps = 113/1112 (10%)
Query: 45 QLTKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVP 104
Q K+ N + TAKYN +FLP LY QF R +N FFL I +LQ IPD+S ++ P
Sbjct: 129 QRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTP 188
Query: 105 LLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEY 164
++ +L + A +++++D+ RHK+D A+N + Q+L +++ W+ + VGD+V ++
Sbjct: 189 MVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNI 248
Query: 165 IPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPAT-SDIKDVDSLMRISGRIECES 223
+PAD +LL+S+EP ++CY+ET ++DGETNLK RQ L T ++ + + G + CE+
Sbjct: 249 VPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEA 308
Query: 224 PNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSP 283
PN ++ FVG + + L +LLRG ++RNT +G+V+Y G DTK+M+N
Sbjct: 309 PNSRMHHFVGCLEWNDK-KYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGKI 367
Query: 284 PLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGG--ASNFG 341
LK + ++ + N ++++F ++ + LV + G + +YL+ +G A+
Sbjct: 368 HLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAESF 427
Query: 342 LNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELG 401
F +F+IL + IP+S+ + E + + FI+WD+ M+Y+P D A AR+++LN+ LG
Sbjct: 428 FVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLG 487
Query: 402 QVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQ--------------FGDEK-TFSDS 446
QV+YIFSDKTGTLT N++ F KC I+G YG +S+ F D K F ++
Sbjct: 488 QVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFHNA 547
Query: 447 SLLENLQNNHPTAPIICEFLTMMAVCHTAV----PEREGDKIIYQAASPDEGALVRAAKQ 502
+LL ++ N A + EF ++A+CHT + P D+++YQAASPDEGALV AA+
Sbjct: 548 ALLHLVRTNGDEA--VREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARN 605
Query: 503 LNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTV 562
+VF RT D+V I LG+E Y++L +++F S RKRMSV+VR P G + LY KGADTV
Sbjct: 606 FGYVFLSRTQDTVTIMELGEERVYQVLAIMDFNSTRKRMSVLVRKPEGAICLYTKGADTV 665
Query: 563 IYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRL 622
I++RL + T + L FA E LRTLC A E++E +++W+ +Q AS +QNR
Sbjct: 666 IFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASLLLQNRA 725
Query: 623 LKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGH 682
L+ QLLGATAIED+LQD VPETI+ L K++IKIW+LTGDKQETA+NIG
Sbjct: 726 QALQ----------QLLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGF 775
Query: 683 SCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKEN----DFALIIDGKTLKYAL 738
+C+LL +N M+++ E + ET + L L +E+ AL+I+G L L
Sbjct: 776 ACELLSEN--MLILEEKEISRILETYWENSNNL---LTRESLSQVKLALVINGDFLDKLL 830
Query: 739 TFGVRQ-------------------------YFLDLALSCKAVICCRVSP---------- 763
++ Y L+L C+ +P
Sbjct: 831 VSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAPPAQDSRARRS 890
Query: 764 ---LQKSEVVEMVKKQVKVV-----------------------TLAIGDGANDVSMIQTA 797
LQ+ V++ K V+ TLAIGDGAND++MI+TA
Sbjct: 891 SEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAIGDGANDINMIKTA 950
Query: 798 HVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYII 857
VGVG++G EG+QA +SD+ + QF +L+ LL++HG W+Y R+ K + Y FYK++ ++
Sbjct: 951 DVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFFYKSMASMMV 1010
Query: 858 EIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQN 917
++WFA NGF+GQ L+E W + L+N++++ +P L +G+FE+ E L+ PELY Q
Sbjct: 1011 QVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEKPELYVVGQK 1070
Query: 918 ALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITV 977
FN VF +G+ S++ F+ L + TA G SD+ V ++++
Sbjct: 1071 DELFNYWVFVQAIAHGVTTSLVNFFMTL-WISRDTA-GPASFSDHQSFAVVVALSCLLSI 1128
Query: 978 CLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLW---PAIPMAPDMSGEAAMLFSSG 1034
++ L YWT I S+ + + S W + P + + +++ S
Sbjct: 1129 TMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFLYADLSVMSSPS 1188
Query: 1035 VFWMGLLFIPVAS---LLLDVVYKVIKRTAFK 1063
+ + LL + + + L L V++ +K K
Sbjct: 1189 ILLVVLLSVSINTFPVLALRVIFPALKELRAK 1220
>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
Length = 1119
Score = 662 bits (1707), Expect = 0.0
Identities = 387/1080 (35%), Positives = 595/1080 (55%), Gaps = 69/1080 (6%)
Query: 37 RTIFINQPQLT--------KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQ 88
RT+F+ ++ +FC+N + ++KY + FLP+ L+ QFRR AN +FL I L+Q
Sbjct: 23 RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
Query: 89 QIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHW 148
D +PT T+ +PL F++ V AIK+ ED RH+ADN VNK ++ N
Sbjct: 83 VTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
Query: 149 EKVNVGDIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKD 208
EK+ VGD+V ++ E P D +LLSS CY+ T++LDGE+N K + T +
Sbjct: 142 EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
Query: 209 VDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVP----LGADQILLRGAQLRNTQWVH 264
+S+ + IECE P LY FVG I + + LG + +LL+GA L+NT+ ++
Sbjct: 202 AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
Query: 265 GIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRR-H 323
G+ VYTG +TK+ N K S VE+ N +++ IL+ + VC+ +W +
Sbjct: 262 GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
Query: 324 SGKDWYLNLNYGGASNFGL-----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDL 378
+ + WY + +FL+F++LFN +IP+S+ VT+E+ KF ++FI+WD
Sbjct: 322 NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
Query: 379 DMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFG 438
D + E + A+ TS+LNEELGQV Y+F+DKTGTLT N M+F +C I G Y +Q
Sbjct: 382 DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
Query: 439 DEKTFSDSSL--LENLQNNHPTAPIICEFLTMMAVCHTAVPER--------EGDKIIYQA 488
D + +D +L + + N FL + +CHT + E ++ Y +
Sbjct: 442 DGLSQTDGTLTYFDKVDKNREEL-----FLRALCLCHTVEIKTNDAVDGATESAELTYIS 496
Query: 489 ASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQE-ERYELLNVLEFTSARKRMSVIVRT 547
+SPDE ALV+ AK+ F F G + +++ +E E YELL+ L F + R+RMSVIV+T
Sbjct: 497 SSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKT 556
Query: 548 PSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEW 607
G + L+CKGAD+ ++ R+ E+T H+E+ A +G RTLC A EI+ D++
Sbjct: 557 QEGDILLFCKGADSAVFPRVQNHEI--ELTKVHVERNAMDGYRTLCVAFKEIAPDDYERI 614
Query: 608 RAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIW 667
A ++Q+R K+E+ ++ IE N+ L+GATA+EDKLQDQ ETIE L A +K+W
Sbjct: 615 NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674
Query: 668 ILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRK------ 721
+LTGDK ETA + ++C+L + N ++ + +++ + R L + +K
Sbjct: 675 VLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFP 734
Query: 722 ------------ENDFALIIDGKTLKYALTFG-------VRQYFLDLALSCKAVICCRVS 762
++ LIIDG TL L + FL + + C AV+CCR++
Sbjct: 735 KSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMA 794
Query: 763 PLQKSEVVEMVKK-QVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQ 821
PLQK+++V MVK + +TL+IGDGANDVSMI +HVG+GI G EG QAA +SDYS+ +
Sbjct: 795 PLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPK 854
Query: 822 FKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLY 881
FK+LK LL+ HG Y R++ + Y FYKN+ + + + F GFS Q L++ + +Y
Sbjct: 855 FKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMY 914
Query: 882 NVMFTAMPPLTLGIFERSCRKENMLKYPELY-KTSQNA-LDFNTKVFWVHCLNGLFHSVI 939
N+ FT++P L + E+ + + P LY K S NA L ++W F +
Sbjct: 915 NICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFL--AAFEGTV 972
Query: 940 LFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGS 999
F+ Q + NGK G V+T +V TV LK L+T +WTW +H IWGS
Sbjct: 973 FFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGS 1032
Query: 1000 IALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIK 1058
+A +V F + +WP + M A + SS W+ ++ + SL +++ V+K
Sbjct: 1033 LAFYVFFSFFWGGIIWPFLKQ-QRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLK 1091
>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
Length = 1132
Score = 662 bits (1707), Expect = 0.0
Identities = 387/1080 (35%), Positives = 595/1080 (55%), Gaps = 69/1080 (6%)
Query: 37 RTIFINQPQLT--------KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQ 88
RT+F+ ++ +FC+N + ++KY + FLP+ L+ QFRR AN +FL I L+Q
Sbjct: 23 RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
Query: 89 QIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHW 148
D +PT T+ +PL F++ V AIK+ ED RH+ADN VNK ++ N
Sbjct: 83 VTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
Query: 149 EKVNVGDIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKD 208
EK+ VGD+V ++ E P D +LLSS CY+ T++LDGE+N K + T +
Sbjct: 142 EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
Query: 209 VDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVP----LGADQILLRGAQLRNTQWVH 264
+S+ + IECE P LY FVG I + + LG + +LL+GA L+NT+ ++
Sbjct: 202 AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
Query: 265 GIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRR-H 323
G+ VYTG +TK+ N K S VE+ N +++ IL+ + VC+ +W +
Sbjct: 262 GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
Query: 324 SGKDWYLNLNYGGASNFGL-----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDL 378
+ + WY + +FL+F++LFN +IP+S+ VT+E+ KF ++FI+WD
Sbjct: 322 NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
Query: 379 DMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFG 438
D + E + A+ TS+LNEELGQV Y+F+DKTGTLT N M+F +C I G Y +Q
Sbjct: 382 DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
Query: 439 DEKTFSDSSL--LENLQNNHPTAPIICEFLTMMAVCHTAVPER--------EGDKIIYQA 488
D + +D +L + + N FL + +CHT + E ++ Y +
Sbjct: 442 DGLSQTDGTLTYFDKVDKNREEL-----FLRALCLCHTVEIKTNDAVDGATESAELTYIS 496
Query: 489 ASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQE-ERYELLNVLEFTSARKRMSVIVRT 547
+SPDE ALV+ AK+ F F G + +++ +E E YELL+ L F + R+RMSVIV+T
Sbjct: 497 SSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKT 556
Query: 548 PSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEW 607
G + L+CKGAD+ ++ R+ E+T H+E+ A +G RTLC A EI+ D++
Sbjct: 557 QEGDILLFCKGADSAVFPRVQNHEI--ELTKVHVERNAMDGYRTLCVAFKEIAPDDYERI 614
Query: 608 RAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIW 667
A ++Q+R K+E+ ++ IE N+ L+GATA+EDKLQDQ ETIE L A +K+W
Sbjct: 615 NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674
Query: 668 ILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRK------ 721
+LTGDK ETA + ++C+L + N ++ + +++ + R L + +K
Sbjct: 675 VLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFP 734
Query: 722 ------------ENDFALIIDGKTLKYALTFG-------VRQYFLDLALSCKAVICCRVS 762
++ LIIDG TL L + FL + + C AV+CCR++
Sbjct: 735 KSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMA 794
Query: 763 PLQKSEVVEMVKK-QVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQ 821
PLQK+++V MVK + +TL+IGDGANDVSMI +HVG+GI G EG QAA +SDYS+ +
Sbjct: 795 PLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPK 854
Query: 822 FKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLY 881
FK+LK LL+ HG Y R++ + Y FYKN+ + + + F GFS Q L++ + +Y
Sbjct: 855 FKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMY 914
Query: 882 NVMFTAMPPLTLGIFERSCRKENMLKYPELY-KTSQNA-LDFNTKVFWVHCLNGLFHSVI 939
N+ FT++P L + E+ + + P LY K S NA L ++W F +
Sbjct: 915 NICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFL--AAFEGTV 972
Query: 940 LFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGS 999
F+ Q + NGK G V+T +V TV LK L+T +WTW +H IWGS
Sbjct: 973 FFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGS 1032
Query: 1000 IALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIK 1058
+A +V F + +WP + M A + SS W+ ++ + SL +++ V+K
Sbjct: 1033 LAFYVFFSFFWGGIIWPFLKQ-QRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLK 1091
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 467 bits (1201), Expect = e-131
Identities = 306/1014 (30%), Positives = 510/1014 (50%), Gaps = 106/1014 (10%)
Query: 37 RTIFINQPQLT--KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVS 94
RT+++ P+ ++ N ++ KYN TFLP L++QF+ N +FL +A Q +P++
Sbjct: 39 RTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMR 98
Query: 95 PTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVG 154
YT VPL F+LAV I+E +E+I+ + D VN + L V + VG
Sbjct: 99 LGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVG 158
Query: 155 DIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMR 214
D++I++ + +PAD + L +SE C++ T LDGET+ K+R + T + L++
Sbjct: 159 DLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQ 218
Query: 215 ISGRIECESPNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQW---------VHG 265
I + E PN +++FVG + +D + + NT W V G
Sbjct: 219 IRSYVYAEEPNIDIHNFVGTFTRE-------DSDPPISESLSIENTLWAGTVVASGTVVG 271
Query: 266 IVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSG 325
+V+YTG + + + N+++P K+ + N ILF L+ +SLV +H
Sbjct: 272 VVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA------LQHFA 325
Query: 326 KDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPT 385
WYL + + F++LF+N+IPISL V L++ K ++ I D +
Sbjct: 326 GRWYLQI------------IRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI----- 368
Query: 386 DTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTFSD 445
+ R+S + E+LG++ Y+ +DKTGTLT N M FK+ + VAYG +S DE
Sbjct: 369 -PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSM--DEVQSHI 425
Query: 446 SSLLENLQNNHPT--------------APIICEFLTMMAVCHTAVPEREGDKI------- 484
S+ + P + + E + +A+CH P E + +
Sbjct: 426 FSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAE 485
Query: 485 --------IYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLG-QEERYELLNVLEFT 535
+YQA+SPDE ALV+ + + GR S+ + + G Q + +L + FT
Sbjct: 486 KQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFT 545
Query: 536 SARKRMSVIVRTPS-GKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCF 594
KRM +IVR S G++ Y KGAD V +A +Y + + A EGLR L
Sbjct: 546 YESKRMGIIVRDESTGEITFYMKGADVV----MAGIVQYNDWLEEECGNMAREGLRVLVV 601
Query: 595 AVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPE 654
A ++E +Q++ A Y +A SV +R LK+ E +E ++LL T +ED+LQ V
Sbjct: 602 AKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRP 661
Query: 655 TIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGM----IVINEGSLDGTRETLSR 710
T+ETL A IK+W+LTGDK ETA + L+ +N + +V N G
Sbjct: 662 TLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRG---------EA 712
Query: 711 HCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVV 770
H +A R+++D AL+I G +L+ L + F++LA C AV+CCR +P QK+++V
Sbjct: 713 HLEL--NAFRRKHDCALVISGDSLEVCLKY-YEYEFMELACQCPAVVCCRCAPTQKAQIV 769
Query: 771 EMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLM 830
+++++ +T A+GDG NDVSMIQ + GVG+ G EG QA+ ++D+SI QFK+L LLM
Sbjct: 770 RLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLM 829
Query: 831 IHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPP 890
+HG +Y R + + ++++ + ++ F+ V F+ L++ + I Y+ ++T P
Sbjct: 830 VHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPV 889
Query: 891 LTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQY 950
+L + ++ + E + YPELYK + K F + L ++ + + L +
Sbjct: 890 FSL-VLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFE- 947
Query: 951 GTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV 1004
S+++ + +T +++T L L W W +A S+A ++
Sbjct: 948 ---------SEFVHIVAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYI 992
>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
Length = 1147
Score = 439 bits (1130), Expect = e-123
Identities = 310/1027 (30%), Positives = 504/1027 (49%), Gaps = 116/1027 (11%)
Query: 35 EVRTIFINQPQLT--KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPD 92
+ RT+++ P+ K N + KYN+ TF+P LY QF+ N +FL I+ Q +P
Sbjct: 114 KARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPA 173
Query: 93 VSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVN 152
+ YT PL F+LAV +E I++ +R + D VN + L V +
Sbjct: 174 LKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQ 233
Query: 153 VGDIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSL 212
VGD++I++ + IP+D V L +SE C+I T LDGET+ K++ + T + + L
Sbjct: 234 VGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDL 293
Query: 213 MRISGRIECESPNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQW---------V 263
IS + + P ++ F G + +D + + NT W V
Sbjct: 294 FSISAYVYAQKPQMDIHSFEGTFTRED-------SDPPIHESLSIENTLWASTIVASGTV 346
Query: 264 HGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRH 323
G+V+YTG +T+ + N+++P K+ ++ N LF L+A+S+V
Sbjct: 347 IGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVG--- 403
Query: 324 SGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYE 383
WY NL F++LF+ +IPISL V L++ K + + D ++
Sbjct: 404 ---PWYRNL------------FRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENI--- 445
Query: 384 PTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQN--------- 434
+ RTS + EELG++ Y+ +DKTGTLT N M FK+ + V+YG +
Sbjct: 446 ---PGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHV 502
Query: 435 --------SQFGDEKTFSDSSLLENLQNNHP-----TAPIICEFLTMMAVCHTAVPEREG 481
SQ G T S+ L Q++ P + I E + + +CH P E
Sbjct: 503 RDSYSQMQSQAGGNNT--GSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYES 560
Query: 482 -------------------DKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDS-LG 521
+ YQA+SPDE ALV+ + + R S+ + + G
Sbjct: 561 RAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSG 620
Query: 522 QEERYELLNVLEFTSARKRMSVIVRTPS-GKLRLYCKGADTVIYDRLAETSKYKEITLKH 580
Q + +L + FTS KRM VIVR S ++ Y KGAD ++ +Y + +
Sbjct: 621 QVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVA----MSPIVQYNDWLEEE 676
Query: 581 LEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLG 640
A EGLRTL A ++E +Q++ + Y +A S+ +R LK+ E +E+ ++LL
Sbjct: 677 CGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLC 736
Query: 641 ATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGS 700
T +ED+LQ V T+E L A IKIW+LTGDK ETA I S L+ + + +
Sbjct: 737 LTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIF---- 792
Query: 701 LDGTRETLSRHCTTLG-DALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICC 759
R+ SR L +A R+++D AL+I G +L+ L + + F++LA C AV+CC
Sbjct: 793 ----RQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHE-FVELACQCPAVVCC 847
Query: 760 RVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSI 819
R SP QK+ +V ++++ T AIGDG NDVSMIQ A G+GI G EG QA+ ++D+SI
Sbjct: 848 RCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSI 907
Query: 820 AQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIG 879
QF+++ LLM+HG +Y R + + ++ +++ ++ F+ V F+ L++ + +
Sbjct: 908 TQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMV 967
Query: 880 LYNVMFTAMPPLTLGIFERSCRKENMLKYPELYK--TSQNALDFNTKVFWVHCLNGLFHS 937
Y ++T P +L + ++ + E + YPELYK T +L F T + WV L ++
Sbjct: 968 GYATIYTMFPVFSL-VLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWV--LISIYQG 1024
Query: 938 VILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIW 997
IL + L + S+++ + +T +++T L L W W +A +
Sbjct: 1025 GILMYGALVLFE----------SEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEF 1074
Query: 998 GSIALWV 1004
S+ +V
Sbjct: 1075 LSLGCYV 1081
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 418 bits (1075), Expect = e-116
Identities = 246/659 (37%), Positives = 370/659 (56%), Gaps = 65/659 (9%)
Query: 440 EKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRA 499
EK D+ LL + P P+ C + Y+A SPDE ALV A
Sbjct: 696 EKQHGDAGLLNGKAESLPGQPLACN-------------------LCYEAESPDEAALVYA 736
Query: 500 AKQLNFVFTGRTPDSVIID--SLGQEERYELLNVLEFTSARKRMSVIVRTP-SGKLRLYC 556
A+ RTP+ V++D +LG ++LL++L F S RKRMSV+VR P S ++ +Y
Sbjct: 737 ARAYQCTLRSRTPEQVMVDFAALGPLT-FQLLHILPFDSVRKRMSVVVRHPLSNQVVVYT 795
Query: 557 KGADTVIYDRLAETSK-----------YKEITLKHLEQFATEGLRTLCFAVAEISESDFQ 605
KGAD+VI + L+ S +E T KHL+ +A +GLRTLC A +S++++
Sbjct: 796 KGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYA 855
Query: 606 EWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIK 665
EW + A TS+ NR L ES +E L LLGAT IED+LQ+ VPE+IE L KA IK
Sbjct: 856 EWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIK 915
Query: 666 IWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTR-------ETLSRHCTTLGDA 718
IW+LTGDKQETA+NI ++CKLL+ + + ++N S D + L + L +
Sbjct: 916 IWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMSTILKELQKKTQALPEQ 975
Query: 719 LRKENDF-------------ALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQ 765
+ D LII GKTL++AL +++ FL+L C+AV+CCR +PLQ
Sbjct: 976 VSLSEDLLQPPVPRDSGLRAGLIITGKTLEFALQESLQKQFLELTSWCQAVVCCRATPLQ 1035
Query: 766 KSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYL 825
KSEVV++V+ ++V+TLAIGDGANDVSMIQ A +G+G+SG EG+QA +SD++++QFK+L
Sbjct: 1036 KSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHL 1095
Query: 826 KNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMF 885
LL++HG W Y R+S ILY FYKN+ + W+ F GFSG + + W + +N++F
Sbjct: 1096 SKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLF 1155
Query: 886 TAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPL 945
T+ PP+ G+ E+ E +++ PELY++ Q + + FW+ L+ + S++ F+ P
Sbjct: 1156 TSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPY 1215
Query: 946 KALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWVV 1005
Q G +D GN + T + V L +E+ TW + I GSI + +
Sbjct: 1216 FTYQ-------GSDTDIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSILSYFL 1268
Query: 1006 FFGIYSSLWPAI--PMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIKRTAF 1062
F ++ ++ P P + ML VF++ + +LL VY+V++ + F
Sbjct: 1269 FAIVFGAMCVTCNPPSNPYWIMQEHML--DPVFYLVCILTTSIALLPRFVYRVLQGSLF 1325
Score = 290 bits (741), Expect = 7e-78
Identities = 160/391 (40%), Positives = 230/391 (58%), Gaps = 9/391 (2%)
Query: 49 FCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFI 108
+ NN + T KY ++ F+PR L+ QF RAAN +FLF+ +L +P V + T++PL+ +
Sbjct: 71 YVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVV 130
Query: 109 LAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVH--WEKVNVGDIVIIKGKEYIP 166
L + AIK+ +ED +++K D +N T+V + + W+ V VGD + + E IP
Sbjct: 131 LTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVIP 190
Query: 167 ADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNR 226
AD VLL S++P +C+IETS LDGE+NLK RQ + ++ + S RIECESPN
Sbjct: 191 ADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRIECESPNN 250
Query: 227 HLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLK 286
L F G + V L + +LLRG +RNT+ V GIVVY GH+TK M N++ P K
Sbjct: 251 DLSRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYK 310
Query: 287 LSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGG------ASNF 340
S +ER N +L +L+ M L +VG IW R+ ++ G + F
Sbjct: 311 RSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMHFFNVPEPDGHIISPLLAGF 370
Query: 341 GLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEEL 400
+ F T IIL LIPISL V++E+VK Q YFI D+D + E D+ R N+ E+L
Sbjct: 371 YM-FWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAEDL 429
Query: 401 GQVKYIFSDKTGTLTCNVMQFKKCTIAGVAY 431
GQ++Y+FSDKTGTLT N M F++C++AG Y
Sbjct: 430 GQIQYLFSDKTGTLTENKMVFRRCSVAGFDY 460
>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
Length = 1461
Score = 406 bits (1043), Expect = e-113
Identities = 231/633 (36%), Positives = 355/633 (56%), Gaps = 49/633 (7%)
Query: 486 YQAASPDEGALVRAAKQLNFVFTGRTPDSVIID-SLGQEERYELLNVLEFTSARKRMSVI 544
Y+A SPDE ALV AA +F RTP+ V + G + LL L F S RKRMSV+
Sbjct: 717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVV 776
Query: 545 VRTP-SGKLRLYCKGADTVIYDRLAETS------------KYKEITLKHLEQFATEGLRT 591
VR P +G++ +Y KGAD+VI D L + + K + T KHL+ +A +GLRT
Sbjct: 777 VRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRT 836
Query: 592 LCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQ 651
LC A +SE DF+ W + + A S+ NR L E+ + +E L LLGAT IED+LQ+
Sbjct: 837 LCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEG 896
Query: 652 VPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRH 711
VP+TI TL +A I++W+LTGDKQETA+NI HSC+LL + + IN + + L+
Sbjct: 897 VPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCA 956
Query: 712 CTTLGD--ALRKEN----------------------DFALIIDGKTLKYALTFGVRQYFL 747
L L+K + + L+IDGKTL + + FL
Sbjct: 957 LEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFL 1016
Query: 748 DLALSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNE 807
+L C++V+CCR +PLQKS +V++V+ +++V+TL+IGDGANDVSMIQ A +G+GISG E
Sbjct: 1017 ELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQE 1076
Query: 808 GLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGF 867
G+QA SSD++I +FK+LK LL++HG W Y+R+++ ++Y YKN+ + W+ F GF
Sbjct: 1077 GMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGF 1136
Query: 868 SGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFW 927
S + + W + +N+ FT++PPL G+ ++ E +L PELYK+ QN+ +N FW
Sbjct: 1137 SSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFW 1196
Query: 928 VHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSY 987
+ ++ + S+I F+ P A + G D G + T + T+ L +E
Sbjct: 1197 ISMVDAFYQSLICFFIPYLAYK-------GSDIDVFTFGTPINTISLTTILLHQAMEMKT 1249
Query: 988 WTWFSHIAIWGSIALWVVFFGIYSSLWPAI--PMAPDMSGEAAMLFSSGVFWMGLLFIPV 1045
WT F + + GS ++ + +Y++ P P E + S+ F++ PV
Sbjct: 1250 WTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQL--SNPTFYLVCFLTPV 1307
Query: 1046 ASLLLDVVYKVIKRTAFKTLVDEVQELEAKSQD 1078
+LL + ++ T K+L+ + Q+++ D
Sbjct: 1308 VALLPRYFFLSLQGTCGKSLISKAQKIDKLPPD 1340
Score = 286 bits (732), Expect = 8e-77
Identities = 163/395 (41%), Positives = 224/395 (56%), Gaps = 15/395 (3%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ N T KY + TFLPR L+ QF R AN +FLF+ +L +P + R T++PL
Sbjct: 65 RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVH--WEKVNVGDIVIIKGKEYI 165
+L V IK+ +ED KRH+ D A+N ++ V W+ V VGD + +K E +
Sbjct: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIV 184
Query: 166 PADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPN 225
PAD +LL SS+P +C++ET++LDGETNLK R + S + I CE PN
Sbjct: 185 PADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIVCEKPN 244
Query: 226 RHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPL 285
HL F G + G + +LLRG +RNT+ GIV+Y GH+TK M N++ P
Sbjct: 245 NHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRY 304
Query: 286 KLSNVERITNVQILILFCILIAMSLVCSVGSAIWN---RRHSGKDW------YLNLNYGG 336
K S +ER N+ I ILI M L+ +VG +IWN H D +L GG
Sbjct: 305 KRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPSALGG 364
Query: 337 ASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNL 396
FLT IIL LIPISL V++E+VK Q +F++ DLD++ E TD + R N+
Sbjct: 365 F----YMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNI 420
Query: 397 NEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAY 431
E+LGQ++YIFSDKTGTLT N M F++CTI G Y
Sbjct: 421 AEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEY 455
>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
Length = 1499
Score = 402 bits (1034), Expect = e-112
Identities = 238/641 (37%), Positives = 361/641 (56%), Gaps = 52/641 (8%)
Query: 478 EREGDKII-YQAASPDEGALVRAAKQLNFVFTGRTPDSVIID--SLGQEERYELLNVLEF 534
E+E ++ + Y+A SPDE ALV AA+ N V R D V ++ LG+ +ELL+ L F
Sbjct: 684 EQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLT-FELLHTLGF 742
Query: 535 TSARKRMSVIVRTP-SGKLRLYCKGADTVIYDRLAETS----------KYKEITLKHLEQ 583
S RKRMSV++R P + ++ +Y KGAD+V+ D L S K + T +L
Sbjct: 743 DSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNV 802
Query: 584 FATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATA 643
+A EGLRTLC A +S+ ++ W + A +S++N L +S +E NL LLGAT
Sbjct: 803 YAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATG 862
Query: 644 IEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDG 703
IED+LQD VPETI L +A ++IW+LTGDKQETA+NI ++CKLL + +I +N S +
Sbjct: 863 IEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEA 922
Query: 704 TRETLSRH-CTTLGDALRKENDF-------------------------ALIIDGKTLKYA 737
L + C L++ + +L+IDG++L YA
Sbjct: 923 CAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYA 982
Query: 738 LTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTA 797
L + FL LA C++V+CCR +PLQKS VV++V+ ++K +TLAIGDGANDVSMIQ A
Sbjct: 983 LEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVA 1042
Query: 798 HVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYII 857
VGVGISG EG+QA +SD+++ +F+YL+ LL++HG W Y+R++ +LY FYKN + +
Sbjct: 1043 DVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGL 1102
Query: 858 EIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQN 917
WF F GFS + ++W + +N++F+++PPL G+ +R +L P+LYK+ QN
Sbjct: 1103 LFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQN 1162
Query: 918 ALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITV 977
++ + FW + + F S++ F P A D G + T ++T
Sbjct: 1163 MEEYRPRTFWFNMADAAFQSLVCFSIPYLAYY-------DSNVDLFTWGTPIVTIALLTF 1215
Query: 978 CLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAI--PMAPDMSGEAAMLFSSGV 1035
L G+ET WTW + I S+ L+ IY++ P P + +A L V
Sbjct: 1216 LLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQA--LLGDPV 1273
Query: 1036 FWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAKS 1076
F++ L PVA+LL + ++ ++ F T + ++L KS
Sbjct: 1274 FYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRKS 1314
Score = 303 bits (775), Expect = 8e-82
Identities = 164/393 (41%), Positives = 238/393 (60%), Gaps = 8/393 (2%)
Query: 51 NNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILA 110
+N + T KY +++FLP+ L+ QF R AN +F+FIALL +P V+ L P+LFILA
Sbjct: 61 DNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILA 120
Query: 111 VAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVH--WEKVNVGDIVIIKGKEYIPAD 168
+ A +++ ED RH++D+ +N V + V+ W++++VGD V ++ E PAD
Sbjct: 121 ITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPAD 180
Query: 169 TVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHL 228
+LLSSS+P +C+IET+NLDGETNLK RQ + S++ + + + IECE PN L
Sbjct: 181 ILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDL 240
Query: 229 YDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLS 288
F G I D L + +LLRG LRNT V GIV+Y GH+TK + N++ P K S
Sbjct: 241 SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS 300
Query: 289 NVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFG------L 342
+ER N +L +L+ MSL +VG +W R+ K + S+
Sbjct: 301 KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY 360
Query: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
+FLT II+ LIPISL V++E+VK Q YFIN D+ ++ E TD+ R N+ E+LGQ
Sbjct: 361 SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ 420
Query: 403 VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNS 435
++YIFSDKTGTLT N M F++CT++GV Y ++
Sbjct: 421 IQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDA 453
>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
Length = 387
Score = 277 bits (708), Expect = 5e-74
Identities = 146/384 (38%), Positives = 223/384 (58%), Gaps = 31/384 (8%)
Query: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
++ +N + T+KYNI+TFLP L+ QF+ AN++FLF+ +LQ IP +S +TT+VPL+
Sbjct: 28 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
Query: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPA 167
+L + A+K+ +D RHK+DN VN +Q+QVL NG + W V VGDI+ ++ +++ A
Sbjct: 88 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
Query: 168 DTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRH 227
D +LLSSSEP +CYIET+ LDGETN+K+RQ +P TS++ D+ L + G + CE PN
Sbjct: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
Query: 228 LYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKL 287
L F G + PL +LLRG LRNT+W G+V++ G DTKLMQNS K
Sbjct: 208 LDKFSGTLYWK-ENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKR 266
Query: 288 SNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGK-----DWYLNLNYGGASNFGL 342
++++R+ N +L +F L+ M ++ ++G+AIW + W ++ S F L
Sbjct: 267 TSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGF-L 325
Query: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
+F ++II+ N ++PISL V Y P+ T ++R S G
Sbjct: 326 SFWSYIIILNTVVPISLYV-------------------RYVPSLTWGLSRESG-----GP 361
Query: 403 VKYIFSDKTGTLTCNVMQFKKCTI 426
++ FS K +L N CT+
Sbjct: 362 IELFFSMKMKSLRSNEKSSSSCTV 385
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 92.4 bits (228), Expect = 2e-18
Identities = 124/486 (25%), Positives = 196/486 (40%), Gaps = 108/486 (22%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHP 457
E +G I SDKTGTLT N M + I G+ Y Q F L
Sbjct: 454 ETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHY---RQIPSPDVFLPKVL--------- 501
Query: 458 TAPIICEFLTMMAVCHTAV--PEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSV 515
+I +++ + + + PE+EG + Q + E AL L FV +
Sbjct: 502 --DLIVNGISINSAYTSKILPPEKEGG-LPRQVGNKTECAL------LGFVTDLKQDYQA 552
Query: 516 IIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTV-------IYDRLA 568
+ + + +E+ Y+ V F S RK MS ++R P+G R+Y KGA + I DR
Sbjct: 553 VRNEVPEEKLYK---VYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKG 609
Query: 569 ETSKYK-----EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLL 623
E +K ++ +E A +GLRT+C A + +++ S +N +L
Sbjct: 610 EAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTE----------PSWDNENEIL 659
Query: 624 KLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHS 683
L + IED ++ +VP+ I +A I + ++TGD TA I
Sbjct: 660 ----------TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATK 709
Query: 684 CKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALIIDGKTLKYAL---TF 740
C +L T GD DF L ++GK +
Sbjct: 710 CGIL--------------------------TPGD------DF-LCLEGKEFNRLIRNEKG 736
Query: 741 GVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVTLAIGDGANDVSM 793
V Q LD + K + R SP K +V+ + +QV VT GDG ND
Sbjct: 737 EVEQEKLD-KIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVT---GDGTNDGPA 792
Query: 794 IQTAHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKN 851
++ A VG +GI+G + + A+ + F + +M G Y+ +SK + + N
Sbjct: 793 LKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKFLQFQLTVN 851
Query: 852 IVLYII 857
+V I+
Sbjct: 852 VVAVIV 857
Score = 33.1 bits (74), Expect = 1.6
Identities = 26/120 (21%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Query: 105 LLFILAVAAIKEIIEDIKRHKADNAVN-----KKQTQVLRNGAWEIVHWEKVNVGDIVII 159
+LF + + + D + K + +++ ++RNG + ++ VGDI +
Sbjct: 155 ILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQV 214
Query: 160 KGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRI 219
K + +PAD +L+ ++ + I+ S+L GE++ +++ L + +M SGR+
Sbjct: 215 KYGDLLPADGILIQGNDLK----IDESSLTGESD-HVKKSLDKDPMLLSGTHVMEGSGRM 269
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 92.4 bits (228), Expect = 2e-18
Identities = 124/486 (25%), Positives = 196/486 (40%), Gaps = 108/486 (22%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHP 457
E +G I SDKTGTLT N M + I G+ Y Q F L
Sbjct: 454 ETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHY---RQIPSPDVFLPKVL--------- 501
Query: 458 TAPIICEFLTMMAVCHTAV--PEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSV 515
+I +++ + + + PE+EG + Q + E AL L FV +
Sbjct: 502 --DLIVNGISINSAYTSKILPPEKEGG-LPRQVGNKTECAL------LGFVTDLKQDYQA 552
Query: 516 IIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTV-------IYDRLA 568
+ + + +E+ Y+ V F S RK MS ++R P+G R+Y KGA + I DR
Sbjct: 553 VRNEVPEEKLYK---VYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKG 609
Query: 569 ETSKYK-----EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLL 623
E +K ++ +E A +GLRT+C A + +++ S +N +L
Sbjct: 610 EAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTE----------PSWDNENEIL 659
Query: 624 KLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHS 683
L + IED ++ +VP+ I +A I + ++TGD TA I
Sbjct: 660 ----------TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATK 709
Query: 684 CKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALIIDGKTLKYAL---TF 740
C +L T GD DF L ++GK +
Sbjct: 710 CGIL--------------------------TPGD------DF-LCLEGKEFNRLIRNEKG 736
Query: 741 GVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVTLAIGDGANDVSM 793
V Q LD + K + R SP K +V+ + +QV VT GDG ND
Sbjct: 737 EVEQEKLD-KIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVT---GDGTNDGPA 792
Query: 794 IQTAHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKN 851
++ A VG +GI+G + + A+ + F + +M G Y+ +SK + + N
Sbjct: 793 LKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKFLQFQLTVN 851
Query: 852 IVLYII 857
+V I+
Sbjct: 852 VVAVIV 857
Score = 33.1 bits (74), Expect = 1.6
Identities = 26/120 (21%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Query: 105 LLFILAVAAIKEIIEDIKRHKADNAVN-----KKQTQVLRNGAWEIVHWEKVNVGDIVII 159
+LF + + + D + K + +++ ++RNG + ++ VGDI +
Sbjct: 155 ILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQV 214
Query: 160 KGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRI 219
K + +PAD +L+ ++ + I+ S+L GE++ +++ L + +M SGR+
Sbjct: 215 KYGDLLPADGILIQGNDLK----IDESSLTGESD-HVKKSLDKDPMLLSGTHVMEGSGRM 269
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
sapiens]
Length = 1198
Score = 90.1 bits (222), Expect = 1e-17
Identities = 174/797 (21%), Positives = 304/797 (38%), Gaps = 148/797 (18%)
Query: 102 LVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQT-QVLRNGAWEIVHWEKVNVGDIVIIK 160
L+ ++ ++ V A + ++ + + + ++Q V+R G + ++ VGDI +K
Sbjct: 158 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVK 217
Query: 161 GKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIE 220
+ +PAD + + ++ + I+ S+L GE++ ++R+ + D D ++ +SG
Sbjct: 218 YGDLLPADGLFIQGNDLK----IDESSLTGESD-QVRKSV-------DKDPML-LSGTHV 264
Query: 221 CESPNRHLYDFVGNIRLDGHGTVPLGA--------DQILLR--GAQLRNTQWVHGIVVYT 270
E R L VG G LGA D+ + GA Q +
Sbjct: 265 MEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAEGGD 324
Query: 271 GHDTKLMQNSTSPPLKLSNVERITNVQI----LILFCI-LIAMSLVCSVGSAIWNRRHSG 325
D K L VQI L++ I +I + L +V + + N+
Sbjct: 325 ADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNK---- 380
Query: 326 KDWYLNLNYGGASNFGLNFLTFIILFNNLIP--ISLLVTLEVVKFTQAYFINWDLDMHYE 383
K W F F+ + + +P + L VT+ + + + +L H +
Sbjct: 381 KPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLD 440
Query: 384 PTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTF 443
+T +G I SDKTGTLT N M + + V Y K
Sbjct: 441 ACET------------MGNATAICSDKTGTLTTNRMTVVQAYVGDVHY---------KEI 479
Query: 444 SDSSLLENLQNNHPTAPIICEFLTMMAVCHTAV--PEREGDKIIYQAASPDEGALVRAAK 501
D S + N T ++ + + + T + PE+EG A P +
Sbjct: 480 PDPSSI-----NTKTMELLINAIAINSAYTTKILPPEKEG-------ALPRQVGNKTECG 527
Query: 502 QLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADT 561
L FV + + + +E+ Y+ V F S RK MS +++ P R+Y KGA
Sbjct: 528 LLGFVLDLKQDYEPVRSQMPEEKLYK---VYTFNSVRKSMSTVIKLPDESFRMYSKGASE 584
Query: 562 VIY------------DRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRA 609
++ R+ E+ K +E A +GLRT+C A + S +W
Sbjct: 585 IVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDW-- 642
Query: 610 VYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWIL 669
++ I L + IED ++ +VPE I +A I + ++
Sbjct: 643 -----------------DNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMV 685
Query: 670 TGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALII 729
TGD TA I C ++ + + EG R +R E
Sbjct: 686 TGDNINTARAIAIKCGIIHPGEDFLCL-EGKEFNRR-------------IRNEKG----- 726
Query: 730 DGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVTL 782
+ Q +D + K + R SP K +V+ + ++QV VT
Sbjct: 727 -----------EIEQERID-KIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVT- 773
Query: 783 AIGDGANDVSMIQTAHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRV 840
GDG ND ++ A VG +GI+G + + A+ + F + +M G Y+ +
Sbjct: 774 --GDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVM-WGRNVYDSI 830
Query: 841 SKCILYCFYKNIVLYII 857
SK + + N+V I+
Sbjct: 831 SKFLQFQLTVNVVAVIV 847
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
sapiens]
Length = 1243
Score = 89.4 bits (220), Expect = 2e-17
Identities = 114/483 (23%), Positives = 185/483 (38%), Gaps = 101/483 (20%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHP 457
E +G I SDKTGTLT N M + + V Y K D S + N
Sbjct: 488 ETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHY---------KEIPDPSSI-----NTK 533
Query: 458 TAPIICEFLTMMAVCHTAV--PEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSV 515
T ++ + + + T + PE+EG A P + L FV +
Sbjct: 534 TMELLINAIAINSAYTTKILPPEKEG-------ALPRQVGNKTECGLLGFVLDLKQDYEP 586
Query: 516 IIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIY----------- 564
+ + +E+ Y+ V F S RK MS +++ P R+Y KGA ++
Sbjct: 587 VRSQMPEEKLYK---VYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAG 643
Query: 565 -DRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLL 623
R+ E+ K +E A +GLRT+C A + S +W
Sbjct: 644 EPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDW---------------- 687
Query: 624 KLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHS 683
++ I L + IED ++ +VPE I +A I + ++TGD TA I
Sbjct: 688 ---DNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIK 744
Query: 684 CKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVR 743
C ++ + + EG R +R E +
Sbjct: 745 CGIIHPGEDFLCL-EGKEFNRR-------------IRNEKG----------------EIE 774
Query: 744 QYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVTLAIGDGANDVSMIQT 796
Q +D + K + R SP K +V+ + ++QV VT GDG ND ++
Sbjct: 775 QERID-KIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVT---GDGTNDGPALKK 830
Query: 797 AHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVL 854
A VG +GI+G + + A+ + F + +M G Y+ +SK + + N+V
Sbjct: 831 ADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVM-WGRNVYDSISKFLQFQLTVNVVA 889
Query: 855 YII 857
I+
Sbjct: 890 VIV 892
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 89.0 bits (219), Expect = 2e-17
Identities = 112/491 (22%), Positives = 204/491 (41%), Gaps = 94/491 (19%)
Query: 401 GQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHPTAP 460
GQ+ + DKTGTLT + + + GV + F + +F+ L P P
Sbjct: 478 GQLNLVCFDKTGTLTRDGLD-----LWGVVSCDRNGFQEVHSFASGQAL-------PWGP 525
Query: 461 IICEFLTMMAVCHTAV---PEREGDKIIYQ---------AASPDEGALVRAAKQLNFVFT 508
+ MA CH+ + +GD + + A S D+ + V
Sbjct: 526 LCAA----MASCHSLILLDGTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKP 581
Query: 509 GRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLA 568
RT V ++ + +L+ F+SA +RM+VIV+ G + KGA +R+A
Sbjct: 582 CRTASQVPVEGIA------ILHQFPFSSALQRMTVIVQEMGGDRLAFMKGAP----ERVA 631
Query: 569 ETSKYKEIT---LKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKL 625
+ + + + L+ + T+G R + A ++ E+D A+T +
Sbjct: 632 SFCQPETVPTSFVSELQIYTTQGFRVIALAYKKL-END--------HHATTLTR------ 676
Query: 626 EESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCK 685
E +E +L LG +E++L+++ +E L+ A I+ ++TGD +TAI +
Sbjct: 677 ----ETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSG 732
Query: 686 LLKKNMGMIVI--------NEGSLDGTRETLSRHCT--------TLGDALR---KENDFA 726
++ ++ +I+I + S+ T +H + D + +E +
Sbjct: 733 MVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYH 792
Query: 727 LIIDGKTLKYALTFGVRQYFLDLA--LSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAI 784
+ GK+ + Q+F L + I R+SP QKS +VE +K V +
Sbjct: 793 FALTGKSFHV-----ISQHFSSLLPKILINGTIFARMSPGQKSSLVEEFQKLDYFVGMC- 846
Query: 785 GDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCI 844
GDGAND ++ AHVG+ +S E A+ + + N+ + R +
Sbjct: 847 GDGANDCGALKMAHVGISLSEQEASVASPFTSKT-------PNIECVPHLIKEGRAALVT 899
Query: 845 LYCFYKNIVLY 855
+C +K + LY
Sbjct: 900 SFCMFKYMALY 910
>gi|148839292 ATPase type 13A3 [Homo sapiens]
Length = 1226
Score = 88.2 bits (217), Expect = 4e-17
Identities = 138/595 (23%), Positives = 243/595 (40%), Gaps = 110/595 (18%)
Query: 401 GQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQF-GDEKTFSDSSLLENLQNNHPTA 459
GQ+ + DKTGTLT + + + G+ +N++F E+ + L+++
Sbjct: 490 GQLNLVCFDKTGTLTEDGLD-----LWGIQRVENARFLSPEENVCNEMLVKS-------- 536
Query: 460 PIICEFLTMMAVCHTAVPER---EGDKI----------IYQAASPDEGAL--------VR 498
+F+ MA CH+ GD + I + A+ +E AL VR
Sbjct: 537 ----QFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGWILEEATEEETALHNRIMPTVVR 592
Query: 499 AAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSG-KLRLYCK 557
KQL T + + L ++ F+SA +RMSV+ R K+ Y K
Sbjct: 593 PPKQLLPESTPAGNQEMELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMK 652
Query: 558 GADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTS 617
GA I L + LE F +G R + A ++ W
Sbjct: 653 GAPEAIAG-LCKPETVPVDFQNVLEDFTKQGFRVIALAHRKLESK--LTWH--------K 701
Query: 618 VQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETA 677
VQN S + IE N+ +G +++KL+ + P +E L KA+I+ ++TGD TA
Sbjct: 702 VQNI------SRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTA 755
Query: 678 INIGHSCKLLKKNMGMIVINE-GSLDGTRETLSRH-------CT---------------- 713
+++ C ++ +I+ DG ++ H C+
Sbjct: 756 VSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVH 815
Query: 714 -TLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLA--LSCKAVICCRVSPLQKSEVV 770
+L D FA+ +GK+ L ++F DL L + R++P QK++++
Sbjct: 816 DSLEDLQMTRYHFAM--NGKSFSVIL-----EHFQDLVPKLMLHGTVFARMAPDQKTQLI 868
Query: 771 EMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLM 830
E ++ V + GDGAND ++ AH G+ +S L+A+ +S ++ ++
Sbjct: 869 EALQNVDYFVGMC-GDGANDCGALKRAHGGISLS---ELEASVASPFT----SKTPSISC 920
Query: 831 IHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPP 890
+ R + +C +K + LY I +F+ +S IL +G + +F +
Sbjct: 921 VPNLIREGRAALITSFCVFKFMALYSIIQYFSVTLLYS--ILSN---LGDFQFLFIDLAI 975
Query: 891 LTLGIFERSCR---KENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFW 942
+ + +F S KE + + P S AL F+ + C+ F S+ FW
Sbjct: 976 ILVVVFTMSLNPAWKELVAQRPPSGLIS-GALLFSVLSQIIICIG--FQSLGFFW 1027
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 87.4 bits (215), Expect = 7e-17
Identities = 111/483 (22%), Positives = 192/483 (39%), Gaps = 101/483 (20%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHP 457
E +G I SDKTGTLT N M + + Y ++ + S+L + +
Sbjct: 462 ETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHY--------KEIPAPSALTPKILD--- 510
Query: 458 TAPIICEFLTMMAVCHTAV--PEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSV 515
++ +++ + T + PE+EG + Q + E AL L FV +
Sbjct: 511 ---LLVHAISINSAYTTKILPPEKEG-ALPRQVGNKTECAL------LGFVLDLKRDFQP 560
Query: 516 IIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYK- 574
+ + + +++ Y+ V F S RK MS ++R P G RL+ KGA ++ +
Sbjct: 561 VREQIPEDKLYK---VYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNG 617
Query: 575 -----------EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLL 623
++ K +E A +GLRT+C A + S +W
Sbjct: 618 ELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDW---------------- 661
Query: 624 KLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHS 683
++ + +L + IED ++ +VPE I +A I + ++TGD TA I
Sbjct: 662 ---DNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAK 718
Query: 684 CKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVR 743
C +++ + + EG R +R E +
Sbjct: 719 CGIIQPGEDFLCL-EGKEFNRR-------------IRNEKG----------------EIE 748
Query: 744 QYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVTLAIGDGANDVSMIQT 796
Q LD K + R SP K +V+ + ++QV VT GDG ND ++
Sbjct: 749 QERLDKVWP-KLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVT---GDGTNDGPALKK 804
Query: 797 AHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVL 854
A VG +GI+G + + A+ + F + +M G Y+ +SK + + N+V
Sbjct: 805 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKFLQFQLTVNVVA 863
Query: 855 YII 857
I+
Sbjct: 864 VIV 866
Score = 33.5 bits (75), Expect = 1.2
Identities = 29/119 (24%), Positives = 61/119 (51%), Gaps = 6/119 (5%)
Query: 102 LVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQT-QVLRNGAWEIVHWEKVNVGDIVIIK 160
L+ ++ ++ V A + ++ + + + ++Q V+RNG V + VGDI +K
Sbjct: 161 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVK 220
Query: 161 GKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRI 219
+ +PAD VL+ +++ + I+ S+L GE++ +R+ + +M SGR+
Sbjct: 221 YGDLLPADGVLIQANDLK----IDESSLTGESD-HVRKSADKDPMLLSGTHVMEGSGRM 274
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 87.4 bits (215), Expect = 7e-17
Identities = 111/483 (22%), Positives = 192/483 (39%), Gaps = 101/483 (20%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHP 457
E +G I SDKTGTLT N M + + Y ++ + S+L + +
Sbjct: 462 ETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHY--------KEIPAPSALTPKILD--- 510
Query: 458 TAPIICEFLTMMAVCHTAV--PEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSV 515
++ +++ + T + PE+EG + Q + E AL L FV +
Sbjct: 511 ---LLVHAISINSAYTTKILPPEKEG-ALPRQVGNKTECAL------LGFVLDLKRDFQP 560
Query: 516 IIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYK- 574
+ + + +++ Y+ V F S RK MS ++R P G RL+ KGA ++ +
Sbjct: 561 VREQIPEDKLYK---VYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNG 617
Query: 575 -----------EITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLL 623
++ K +E A +GLRT+C A + S +W
Sbjct: 618 ELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDW---------------- 661
Query: 624 KLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHS 683
++ + +L + IED ++ +VPE I +A I + ++TGD TA I
Sbjct: 662 ---DNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAK 718
Query: 684 CKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVR 743
C +++ + + EG R +R E +
Sbjct: 719 CGIIQPGEDFLCL-EGKEFNRR-------------IRNEKG----------------EIE 748
Query: 744 QYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVTLAIGDGANDVSMIQT 796
Q LD K + R SP K +V+ + ++QV VT GDG ND ++
Sbjct: 749 QERLDKVWP-KLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVT---GDGTNDGPALKK 804
Query: 797 AHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVL 854
A VG +GI+G + + A+ + F + +M G Y+ +SK + + N+V
Sbjct: 805 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKFLQFQLTVNVVA 863
Query: 855 YII 857
I+
Sbjct: 864 VIV 866
Score = 33.5 bits (75), Expect = 1.2
Identities = 29/119 (24%), Positives = 61/119 (51%), Gaps = 6/119 (5%)
Query: 102 LVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQT-QVLRNGAWEIVHWEKVNVGDIVIIK 160
L+ ++ ++ V A + ++ + + + ++Q V+RNG V + VGDI +K
Sbjct: 161 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVK 220
Query: 161 GKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRI 219
+ +PAD VL+ +++ + I+ S+L GE++ +R+ + +M SGR+
Sbjct: 221 YGDLLPADGVLIQANDLK----IDESSLTGESD-HVRKSADKDPMLLSGTHVMEGSGRM 274
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 79.7 bits (195), Expect = 1e-14
Identities = 174/756 (23%), Positives = 300/756 (39%), Gaps = 148/756 (19%)
Query: 128 NAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIPADTVLLSSSEPQAMCYIETSN 187
N + +Q V+R+ + + E++ VGDIV +KG + IPAD +LSS C ++ S+
Sbjct: 177 NKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQG----CRVDNSS 232
Query: 188 LDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVPLGA 247
L GE+ + P +S+ + L E+ N Y
Sbjct: 233 LTGESEPQ-----PRSSEFTHENPL---------ETKNICFYSTT--------------- 263
Query: 248 DQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIA 307
L G V G+V+ TG D ++ + S + N + T + I I + I
Sbjct: 264 ---CLEGT-------VTGMVINTG-DRTIIGHIASLASGVGNEK--TPIAIEIEHFVHIV 310
Query: 308 MSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVK 367
+ S+G + S K L+ + FL II+ N +P LL T+ V
Sbjct: 311 AGVAVSIGILFFIIAVSLKYQVLD---------SIIFLIGIIVAN--VPEGLLATVTVTL 359
Query: 368 FTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIA 427
A + + + E LG I SDKTGTLT N M T+A
Sbjct: 360 SLTAKRM----------AKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM-----TVA 404
Query: 428 GVAYGQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAV--PEREGDKII 485
+ F ++ +D+S + Q ++ ++ +C+ A P +E I+
Sbjct: 405 HL------WFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIM 458
Query: 486 YQAASPD--EGALVRAAKQLNFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSV 543
+A D E AL++ + + ++ D + +R + + F S K
Sbjct: 459 KKAVIGDASETALLKFS------------EVILGDVMEIRKRNRKVAEIPFNSTNKFQLS 506
Query: 544 I--VRTPSGK-LRLYCKGADTVIYDRLA------ETSKYKEITLKHLEQFATE----GLR 590
I + P GK + KGA I ++ + E + T K E G R
Sbjct: 507 IHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGER 566
Query: 591 TLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQD 650
L F + +F E + S + S NL +G ++ D +
Sbjct: 567 VLGFCHLYLPADEFPE--------TYSFDIDAMNFPTS------NLCFVGLLSMIDPPRS 612
Query: 651 QVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSR 710
VP+ + A IK+ ++TGD TA K + K++G+I N T E ++
Sbjct: 613 TVPDAVTKCRSAGIKVIMVTGDHPITA-------KAIAKSVGIISAN----SETVEDIAH 661
Query: 711 HCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVV 770
+ + K + A ++ G LK + + ++ + + ++ R SP QK +V
Sbjct: 662 RLNIAVEQVNKRDAKAAVVTGMELKDMSS----EQLDEILANYQEIVFARTSPQQKLIIV 717
Query: 771 EMVKKQVKVVTLAIGDGANDVSMIQTAHVGV--GISGNEGLQAANSSDYSIAQFKYLKNL 828
E ++Q VV + GDG ND ++ A +G+ GI+G++ A N++D + + +
Sbjct: 718 EGCQRQDAVVAVT-GDGVNDSPALKKADIGIAMGIAGSDA--AKNAADMVLLDDNFASIV 774
Query: 829 LMI-HGAWNYNRVSKCILYCFYKNI------VLYII 857
+ G ++ + K I Y KNI ++YII
Sbjct: 775 TGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYII 810
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 73.6 bits (179), Expect = 1e-12
Identities = 112/483 (23%), Positives = 190/483 (39%), Gaps = 100/483 (20%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHP 457
E +G I SDKTGTLT N M + I Y +K ++ N+ +
Sbjct: 464 ETMGNATAICSDKTGTLTMNRMTVVQAYINEKHY--------KKVPEPEAIPPNILSYLV 515
Query: 458 TA-PIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVI 516
T + C + + + PE+EG + + E AL+ L + +
Sbjct: 516 TGISVNCAYTSKILP-----PEKEGG-LPRHVGNKTECALLGLLLDLKRDYQD------V 563
Query: 517 IDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDR----LAETSK 572
+ + +E Y+ V F S RK MS +++ G R++ KGA +I + L+ +
Sbjct: 564 RNEIPEEALYK---VYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGE 620
Query: 573 YK--------EITLKHLEQFATEGLRTLCFAVAEISESDFQ-EWRAVYQRASTSVQNRLL 623
K +I +E A+EGLRT+C A + + + EW
Sbjct: 621 AKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEW---------------- 664
Query: 624 KLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHS 683
++ I L + IED ++ +VP+ I+ +A I + ++TGD TA I
Sbjct: 665 ---DNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATK 721
Query: 684 CKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVR 743
C +L + + EG R +R E +
Sbjct: 722 CGILHPGEDFLCL-EGKDFNRR-------------IRNEKG----------------EIE 751
Query: 744 QYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVTLAIGDGANDVSMIQT 796
Q +D + K + R SP K +V+ + ++QV VT GDG ND ++
Sbjct: 752 QERID-KIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVT---GDGTNDGPALKK 807
Query: 797 AHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVL 854
A VG +GI+G + + A+ + F + +M G Y+ +SK + + N+V
Sbjct: 808 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKFLQFQLTVNVVA 866
Query: 855 YII 857
I+
Sbjct: 867 VIV 869
Score = 31.6 bits (70), Expect = 4.5
Identities = 26/119 (21%), Positives = 60/119 (50%), Gaps = 6/119 (5%)
Query: 102 LVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQT-QVLRNGAWEIVHWEKVNVGDIVIIK 160
L+ ++ ++ V A + ++ + + + ++Q V+R G + + VGDI +K
Sbjct: 160 LLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVK 219
Query: 161 GKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRI 219
+ +PAD +L+ ++ + I+ S+L GE++ +++ L + +M SGR+
Sbjct: 220 YGDLLPADGILIQGNDLK----IDESSLTGESD-HVKKSLDKDPLLLSGTHVMEGSGRM 273
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 73.6 bits (179), Expect = 1e-12
Identities = 112/483 (23%), Positives = 190/483 (39%), Gaps = 100/483 (20%)
Query: 398 EELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTFSDSSLLENLQNNHP 457
E +G I SDKTGTLT N M + I Y +K ++ N+ +
Sbjct: 464 ETMGNATAICSDKTGTLTMNRMTVVQAYINEKHY--------KKVPEPEAIPPNILSYLV 515
Query: 458 TA-PIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVI 516
T + C + + + PE+EG + + E AL+ L + +
Sbjct: 516 TGISVNCAYTSKILP-----PEKEGG-LPRHVGNKTECALLGLLLDLKRDYQD------V 563
Query: 517 IDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIYDR----LAETSK 572
+ + +E Y+ V F S RK MS +++ G R++ KGA +I + L+ +
Sbjct: 564 RNEIPEEALYK---VYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGE 620
Query: 573 YK--------EITLKHLEQFATEGLRTLCFAVAEISESDFQ-EWRAVYQRASTSVQNRLL 623
K +I +E A+EGLRT+C A + + + EW
Sbjct: 621 AKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEW---------------- 664
Query: 624 KLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHS 683
++ I L + IED ++ +VP+ I+ +A I + ++TGD TA I
Sbjct: 665 ---DNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATK 721
Query: 684 CKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVR 743
C +L + + EG R +R E +
Sbjct: 722 CGILHPGEDFLCL-EGKDFNRR-------------IRNEKG----------------EIE 751
Query: 744 QYFLDLALSCKAVICCRVSPLQKSEVVEMV-------KKQVKVVTLAIGDGANDVSMIQT 796
Q +D + K + R SP K +V+ + ++QV VT GDG ND ++
Sbjct: 752 QERID-KIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVT---GDGTNDGPALKK 807
Query: 797 AHVG--VGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVL 854
A VG +GI+G + + A+ + F + +M G Y+ +SK + + N+V
Sbjct: 808 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKFLQFQLTVNVVA 866
Query: 855 YII 857
I+
Sbjct: 867 VIV 869
Score = 31.6 bits (70), Expect = 4.5
Identities = 26/119 (21%), Positives = 60/119 (50%), Gaps = 6/119 (5%)
Query: 102 LVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQT-QVLRNGAWEIVHWEKVNVGDIVIIK 160
L+ ++ ++ V A + ++ + + + ++Q V+R G + + VGDI +K
Sbjct: 160 LLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVK 219
Query: 161 GKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRI 219
+ +PAD +L+ ++ + I+ S+L GE++ +++ L + +M SGR+
Sbjct: 220 YGDLLPADGILIQGNDLK----IDESSLTGESD-HVKKSLDKDPLLLSGTHVMEGSGRM 273
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
[Homo sapiens]
Length = 994
Score = 73.2 bits (178), Expect = 1e-12
Identities = 119/503 (23%), Positives = 197/503 (39%), Gaps = 103/503 (20%)
Query: 389 AMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTFSDSSL 448
A+ R+ E LG I SDKTGTLT N M K I G +E + + S+
Sbjct: 331 AIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLL-NEFSITGSTY 389
Query: 449 L---ENLQNNHPTAP----IICEFLTMMAVCHTAVPEREGDKIIYQ-AASPDEGALVRAA 500
E L+N+ P P + E T+ A+C+ + + K +Y+ E AL
Sbjct: 390 APEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLV 449
Query: 501 KQLNFVFTGRTPDSVIIDSLGQEERYELLN-----------VLEFTSARKRMSVIV---- 545
+++N T + SL + ER N LEF+ RK MSV
Sbjct: 450 EKMNVFNTD-------VRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAK 502
Query: 546 --RTPSGKLRLYCKGADTVIYD----------RLAETSKYKEITLKHLEQFATEGLRTLC 593
R G +++ KGA + D R+ T KE + ++++ T C
Sbjct: 503 SSRAAVGN-KMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRC 561
Query: 594 FAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELI--EKNLQLLGATAIEDKLQDQ 651
A+A T + + L++S + E +L +G + D + +
Sbjct: 562 LALA---------------TRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKE 606
Query: 652 VPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRH 711
V +I+ A I++ ++TGD + TAI I C + +G+ NE D R R
Sbjct: 607 VTGSIQLCRDAGIRVIMITGDNKGTAIAI---C----RRIGIFGENEEVAD--RAYTGRE 657
Query: 712 CTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVIC-CRVSPLQKSEVV 770
L A ++E +C+ C RV P KS++V
Sbjct: 658 FDDLPLAEQRE-----------------------------ACRRACCFARVEPSHKSKIV 688
Query: 771 EMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLM 830
E ++ + +T GDG ND ++ A +G+ + G+ A +S+ +A + +
Sbjct: 689 EYLQSYDE-ITAMTGDGVNDAPALKKAEIGIAM-GSGTAVAKTASEMVLADDNFSTIVAA 746
Query: 831 I-HGAWNYNRVSKCILYCFYKNI 852
+ G YN + + I Y N+
Sbjct: 747 VEEGRAIYNNMKQFIRYLISSNV 769
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,774,327
Number of Sequences: 37866
Number of extensions: 1601054
Number of successful extensions: 3927
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 3606
Number of HSP's gapped (non-prelim): 158
length of query: 1149
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1036
effective length of database: 13,968,660
effective search space: 14471531760
effective search space used: 14471531760
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.