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Search of human proteins with 157388983
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157388983 TBC1 domain family, member 19 [Homo sapiens]
(526 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157388983 TBC1 domain family, member 19 [Homo sapiens] 1044 0.0
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 41 0.003
gi|34147456 TBC domain-containing protein kinase-like [Homo sapi... 40 0.005
gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] 38 0.020
gi|38348348 TBC1 domain family, member 10C [Homo sapiens] 38 0.020
gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] 38 0.026
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 37 0.044
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 37 0.044
gi|222352143 TBC1 domain family, member 2 [Homo sapiens] 35 0.13
gi|221139909 TBC1 domain family, member 7 isoform b [Homo sapiens] 35 0.13
gi|221139907 TBC1 domain family, member 7 isoform a [Homo sapiens] 35 0.13
gi|221139904 TBC1 domain family, member 7 isoform a [Homo sapiens] 35 0.13
gi|7706041 TBC1 domain family, member 7 isoform a [Homo sapiens] 35 0.13
gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 35 0.22
gi|217035118 TBC1 domain family, member 23 [Homo sapiens] 33 0.49
gi|29648315 small G protein signaling modulator 3 [Homo sapiens] 33 0.49
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 32 1.1
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 32 1.1
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 32 1.1
gi|148806902 TBC1 domain family, member 12 [Homo sapiens] 32 1.1
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho... 32 1.4
gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo... 31 2.4
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 31 3.2
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 31 3.2
gi|38327034 ubiquitination factor E4B isoform 2 [Homo sapiens] 31 3.2
gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens] 31 3.2
gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens] 30 4.2
gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] 30 4.2
gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] 30 4.2
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso... 30 5.4
>gi|157388983 TBC1 domain family, member 19 [Homo sapiens]
Length = 526
Score = 1044 bits (2700), Expect = 0.0
Identities = 526/526 (100%), Positives = 526/526 (100%)
Query: 1 MLQEESDLSLIIAQIVQKLKGSNLYSQLERQAWASLQRPEIKLESLKEDIKEFFKISGWE 60
MLQEESDLSLIIAQIVQKLKGSNLYSQLERQAWASLQRPEIKLESLKEDIKEFFKISGWE
Sbjct: 1 MLQEESDLSLIIAQIVQKLKGSNLYSQLERQAWASLQRPEIKLESLKEDIKEFFKISGWE 60
Query: 61 KKLQNAVYSELSVFPLPSHPAAPPEHLKEPLVYMRKAQGSWEKRILKSLNSMCTELSIPL 120
KKLQNAVYSELSVFPLPSHPAAPPEHLKEPLVYMRKAQGSWEKRILKSLNSMCTELSIPL
Sbjct: 61 KKLQNAVYSELSVFPLPSHPAAPPEHLKEPLVYMRKAQGSWEKRILKSLNSMCTELSIPL 120
Query: 121 ARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYENGDSLSFRT 180
ARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYENGDSLSFRT
Sbjct: 121 ARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYENGDSLSFRT 180
Query: 181 HLGLIQVPLKVKDIPELKECFVELGLNIGQLGIDDSTQVPPELFENEHVRIGQKVLAEQD 240
HLGLIQVPLKVKDIPELKECFVELGLNIGQLGIDDSTQVPPELFENEHVRIGQKVLAEQD
Sbjct: 181 HLGLIQVPLKVKDIPELKECFVELGLNIGQLGIDDSTQVPPELFENEHVRIGQKVLAEQD 240
Query: 241 SAAAQQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVK 300
SAAAQQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVK
Sbjct: 241 SAAAQQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVK 300
Query: 301 LTASNDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPP 360
LTASNDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPP
Sbjct: 301 LTASNDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPP 360
Query: 361 NGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFET 420
NGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFET
Sbjct: 361 NGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFET 420
Query: 421 LLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVL 480
LLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVL
Sbjct: 421 LLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVL 480
Query: 481 AAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKVMPLLQIFLFATVT 526
AAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKVMPLLQIFLFATVT
Sbjct: 481 AAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKVMPLLQIFLFATVT 526
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 40.8 bits (94), Expect = 0.003
Identities = 46/210 (21%), Positives = 78/210 (37%), Gaps = 43/210 (20%)
Query: 248 IRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTASNDD 307
+R G P ALR E+W L+ + V Y L T D S I +D+ T D
Sbjct: 563 VRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQD----SAITRDINRTFPAHD 618
Query: 308 YYFVF----EDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGV 363
Y+ +D LY++ +S + Y +G+ L + + P
Sbjct: 619 YFKDTGGDGQDSLYKICKAYSVYDEEIG------------YCQGQSFLAAVLLLHMPEE- 665
Query: 364 IPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQ 423
FS+ V + F Y Q F +++ +F+ E L+Q
Sbjct: 666 ---QAFSVLVK-IMFDYGLRELFKQNFEDLHCKFY------------------QLERLMQ 703
Query: 424 TYLPQLFYHLREIGAQPLRISFKWMVRAFS 453
Y+P L+ H +I + + +W + F+
Sbjct: 704 EYIPDLYNHFLDISLEAHMYASQWFLTLFT 733
>gi|34147456 TBC domain-containing protein kinase-like [Homo
sapiens]
Length = 830
Score = 40.0 bits (92), Expect = 0.005
Identities = 28/135 (20%), Positives = 55/135 (40%), Gaps = 2/135 (1%)
Query: 339 SPPKSYIRGKLGLEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFF 398
S P+ + + + L+ + V +P ++ + G AP +L L ++ +
Sbjct: 457 SSPEGHAKFRRVLKAWVVSHPD--LVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKY 514
Query: 399 FRLHSISSHPSGIVSLCLLFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLAT 458
+ + I +F ++ + P+L HL EIG P + W + F+
Sbjct: 515 LYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPL 574
Query: 459 DQLLLLWDRILGYNS 473
++ LWD +L NS
Sbjct: 575 HKIFHLWDTLLLGNS 589
>gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens]
Length = 963
Score = 38.1 bits (87), Expect = 0.020
Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 16/118 (13%)
Query: 417 LFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEI 476
+F L+ LP+L H + I+F W + F + +D L +WD L Y ++
Sbjct: 801 VFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFL-YEGPKV 859
Query: 477 LAVLAAAVFAFRAVNLMEV---------------TSLAAAEAVLADLSTLKVMPLLQI 519
+ A A+F ++ ++++ T L A + + L PL QI
Sbjct: 860 IFRFALALFKYKEEEILKLQDSMSIFKYLRYFTRTILDARKLISISFGDLNPFPLRQI 917
>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
Length = 446
Score = 38.1 bits (87), Expect = 0.020
Identities = 41/173 (23%), Positives = 69/173 (39%), Gaps = 17/173 (9%)
Query: 351 LEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSK----LYQIFREMYVRFFFRLHSISS 406
L+ Y ++ P G G VA + ++ P + L QI E+Y+ ++
Sbjct: 164 LKAYTLYRPEQGYCQAQG---PVAAVLLMHLPPEEAFWCLVQIC-EVYLPGYY-----GP 214
Query: 407 HPSGIVSLCLLFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWD 466
H + +F LL+ LP + HL+++G PL +W + F+ L +L +WD
Sbjct: 215 HMEAVRLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWD 274
Query: 467 RILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKVMPLLQI 519
L E VL + L A +L L L+ +P Q+
Sbjct: 275 AFLS----EGARVLFRVGLTLVRLALGTAEQRGACPGLLETLGALRAIPPAQL 323
>gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens]
Length = 914
Score = 37.7 bits (86), Expect = 0.026
Identities = 19/79 (24%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Query: 417 LFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEI 476
+F L+ LP+L H + I+F W + F + +D L +WD L Y ++
Sbjct: 801 VFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFL-YEGPKV 859
Query: 477 LAVLAAAVFAFRAVNLMEV 495
+ A A+F ++ ++++
Sbjct: 860 IFRFALALFKYKEEEILKL 878
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 37.0 bits (84), Expect = 0.044
Identities = 53/252 (21%), Positives = 94/252 (37%), Gaps = 39/252 (15%)
Query: 245 QQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTAS 304
++ IR+G P RA +W L+ + + P Y E LK + + LI +D+ T
Sbjct: 109 KELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKMSSP-----CEKLIRRDIARTYP 163
Query: 305 NDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGVI 364
++ F +D L Q +L +V+ A++ Y +G
Sbjct: 164 EHEF-FKGQDSLGQEVLF-----NVMK--AYSLVDREVGYCQG----------------- 198
Query: 365 PFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLL-FETLLQ 423
S ++ L + + + +F + + RL + + LC+ FE +LQ
Sbjct: 199 -----SAFIVGLLLMQMPEEEAFCVFVRLMQEY--RLRELFKPSMAELGLCIYQFEYMLQ 251
Query: 424 TYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAA 483
LP L H R + W + F ++D I Y LEI+ + A
Sbjct: 252 EQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFD-IFMYEGLEIVFRVGLA 310
Query: 484 VFAFRAVNLMEV 495
+ LM++
Sbjct: 311 LLQVNQAELMQL 322
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 37.0 bits (84), Expect = 0.044
Identities = 53/252 (21%), Positives = 94/252 (37%), Gaps = 39/252 (15%)
Query: 245 QQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTAS 304
++ IR+G P RA +W L+ + + P Y E LK + + LI +D+ T
Sbjct: 109 KELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKMSSP-----CEKLIRRDIARTYP 163
Query: 305 NDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGVI 364
++ F +D L Q +L +V+ A++ Y +G
Sbjct: 164 EHEF-FKGQDSLGQEVLF-----NVMK--AYSLVDREVGYCQG----------------- 198
Query: 365 PFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLL-FETLLQ 423
S ++ L + + + +F + + RL + + LC+ FE +LQ
Sbjct: 199 -----SAFIVGLLLMQMPEEEAFCVFVRLMQEY--RLRELFKPSMAELGLCIYQFEYMLQ 251
Query: 424 TYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAA 483
LP L H R + W + F ++D I Y LEI+ + A
Sbjct: 252 EQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFD-IFMYEGLEIVFRVGLA 310
Query: 484 VFAFRAVNLMEV 495
+ LM++
Sbjct: 311 LLQVNQAELMQL 322
>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
Length = 917
Score = 35.4 bits (80), Expect = 0.13
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 417 LFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRIL----GYN 472
+ + LL LP+L HL + ++F W + F+ L ++ LL +WD L YN
Sbjct: 762 VLQDLLSEKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYEGTKYN 821
Query: 473 SLEIL 477
EIL
Sbjct: 822 EKEIL 826
>gi|221139909 TBC1 domain family, member 7 isoform b [Homo sapiens]
Length = 266
Score = 35.4 bits (80), Expect = 0.13
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Query: 418 FETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEIL 477
FE L +L HLR A P W R F+G L L +WD+++ S +IL
Sbjct: 150 FEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVS-GSCKIL 208
Query: 478 AVLAAAVFAFRAVNLMEVTS 497
+A + + +M + S
Sbjct: 209 VFVAVEILLTFKIKVMALNS 228
>gi|221139907 TBC1 domain family, member 7 isoform a [Homo sapiens]
Length = 293
Score = 35.4 bits (80), Expect = 0.13
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Query: 418 FETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEIL 477
FE L +L HLR A P W R F+G L L +WD+++ S +IL
Sbjct: 177 FEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVS-GSCKIL 235
Query: 478 AVLAAAVFAFRAVNLMEVTS 497
+A + + +M + S
Sbjct: 236 VFVAVEILLTFKIKVMALNS 255
>gi|221139904 TBC1 domain family, member 7 isoform a [Homo sapiens]
Length = 293
Score = 35.4 bits (80), Expect = 0.13
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Query: 418 FETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEIL 477
FE L +L HLR A P W R F+G L L +WD+++ S +IL
Sbjct: 177 FEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVS-GSCKIL 235
Query: 478 AVLAAAVFAFRAVNLMEVTS 497
+A + + +M + S
Sbjct: 236 VFVAVEILLTFKIKVMALNS 255
>gi|7706041 TBC1 domain family, member 7 isoform a [Homo sapiens]
Length = 293
Score = 35.4 bits (80), Expect = 0.13
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Query: 418 FETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEIL 477
FE L +L HLR A P W R F+G L L +WD+++ S +IL
Sbjct: 177 FEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVS-GSCKIL 235
Query: 478 AVLAAAVFAFRAVNLMEVTS 497
+A + + +M + S
Sbjct: 236 VFVAVEILLTFKIKVMALNS 255
>gi|68299759 ecotropic viral integration site 5 [Homo sapiens]
Length = 810
Score = 34.7 bits (78), Expect = 0.22
Identities = 46/252 (18%), Positives = 91/252 (36%), Gaps = 39/252 (15%)
Query: 245 QQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTAS 304
++ + +G P RA +W L+ + S P Y E LK + LI +D+ T
Sbjct: 157 KELVHKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSP-----CEKLIRRDIARTYP 211
Query: 305 NDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGVI 364
+++ + +VL + A++ Y +G
Sbjct: 212 EHNFFKEKDSLGQEVLFNVMK--------AYSLVDREVGYCQG----------------- 246
Query: 365 PFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLL-FETLLQ 423
S ++ L + + + +F ++ + RL + + LC+ FE ++Q
Sbjct: 247 -----SAFIVGLLLMQMPEEEAFCVFVKLMQDY--RLRELFKPSMAELGLCMYQFECMIQ 299
Query: 424 TYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAA 483
+LP+LF H + + W + F ++D I LEI+ + A
Sbjct: 300 EHLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFD-IFMSEGLEIVFRVGLA 358
Query: 484 VFAFRAVNLMEV 495
+ LM++
Sbjct: 359 LLQMNQAELMQL 370
>gi|217035118 TBC1 domain family, member 23 [Homo sapiens]
Length = 684
Score = 33.5 bits (75), Expect = 0.49
Identities = 47/220 (21%), Positives = 79/220 (35%), Gaps = 46/220 (20%)
Query: 253 PTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTASNDDYYFVF 312
P LRA++W + LN++ + + + ++ + DL + I+KD
Sbjct: 46 PADLRAKVWKIALNVAGKGDSLASWDGIL------DLPEQNTIHKDC------------- 86
Query: 313 EDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGVIPFHGFSMY 372
L F SV P + L +E FY + I + +
Sbjct: 87 --------LQFIDQLSV----------PEEKAAELLLDIESVITFYCKSRNIKYSTSLSW 128
Query: 373 V---APLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTYLPQL 429
+ PL L S LY F + ++ R S P LF L+Q + P+L
Sbjct: 129 IHLLKPLVHLQLPRSDLYNCFYAIMNKYIPRDCSQKGRPFH------LFRLLIQYHEPEL 182
Query: 430 FYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRIL 469
+L P + W+ F+ Y +T+ +WD L
Sbjct: 183 CSYLDTKKITPDSYALNWLGSLFACYCSTEVTQAIWDGYL 222
>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
Length = 749
Score = 33.5 bits (75), Expect = 0.49
Identities = 54/272 (19%), Positives = 98/272 (36%), Gaps = 39/272 (14%)
Query: 241 SAAAQQYIRQGSPTALRAELWALILN-ISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDV 299
S + + G P +R +LW + + + L Y ++ N + + I KD+
Sbjct: 104 SEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDL 163
Query: 300 KLTASNDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYP 359
T ++ CF+ + S P R + L A YP
Sbjct: 164 LRTMPSN--------------ACFA---------SMGSIGVP----RLRRVLRALAWLYP 196
Query: 360 PNGVIPFHGFSMYVAPLCFLYHEPSKLYQ---IFREMYVRFFFRLHSISSHPSGIVSLCL 416
G G M A L E + I ++ +F S+ G+ +
Sbjct: 197 EIGYC--QGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYF-----STTLLGVQTDQR 249
Query: 417 LFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEI 476
+ L+ YLP+L L+E + I+ W + AF+ + LL +WD + Y +
Sbjct: 250 VLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWD-LFFYEGSRV 308
Query: 477 LAVLAAAVFAFRAVNLMEVTSLAAAEAVLADL 508
L L + + L++ + A+ L+D+
Sbjct: 309 LFQLTLGMLHLKEEELIQSENSASIFNTLSDI 340
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/77 (24%), Positives = 37/77 (48%)
Query: 42 KLESLKEDIKEFFKISGWEKKLQNAVYSELSVFPLPSHPAAPPEHLKEPLVYMRKAQGSW 101
+L+ LK + +F+++ + A +E+S + S P+APP+ + SW
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSW 630
Query: 102 EKRILKSLNSMCTELSI 118
+ ++ N + TE SI
Sbjct: 631 QPPPVEKQNGIITEYSI 647
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
2 precursor [Homo sapiens]
Length = 1899
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/77 (24%), Positives = 37/77 (48%)
Query: 42 KLESLKEDIKEFFKISGWEKKLQNAVYSELSVFPLPSHPAAPPEHLKEPLVYMRKAQGSW 101
+L+ LK + +F+++ + A +E+S + S P+APP+ + SW
Sbjct: 558 RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSW 617
Query: 102 EKRILKSLNSMCTELSI 118
+ ++ N + TE SI
Sbjct: 618 QPPPVEKQNGIITEYSI 634
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform
3 precursor [Homo sapiens]
Length = 1903
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/77 (24%), Positives = 37/77 (48%)
Query: 42 KLESLKEDIKEFFKISGWEKKLQNAVYSELSVFPLPSHPAAPPEHLKEPLVYMRKAQGSW 101
+L+ LK + +F+++ + A +E+S + S P+APP+ + SW
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSW 630
Query: 102 EKRILKSLNSMCTELSI 118
+ ++ N + TE SI
Sbjct: 631 QPPPVEKQNGIITEYSI 647
>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
Length = 775
Score = 32.3 bits (72), Expect = 1.1
Identities = 52/228 (22%), Positives = 87/228 (38%), Gaps = 35/228 (15%)
Query: 250 QGSPTALRAELWALILN--ISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTASNDD 307
QG P ++R ++W+L + ++ PE YE + + +K T+S +D
Sbjct: 483 QGLPPSVRGKVWSLAVGNELNITPE---LYEIFLSRAKER--------WKSFSETSSEND 531
Query: 308 YYFVF----EDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGV 363
V E L + L SR L + F P + LG Y + P G
Sbjct: 532 TEGVSVADREASLELIKLDISRTFPSL--YIFQKGGPYHDVLHSILGA--YTCYRPDVGY 587
Query: 364 IPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVR----FFFRL-HSISSHPSGIVSLCLLF 418
+ G S ++A + L E + + F + + FFR+ HS+ ++ F
Sbjct: 588 V--QGMS-FIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSM------MLKYFATF 638
Query: 419 ETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWD 466
E + L +LF H + P W+ +S L D +WD
Sbjct: 639 EVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWD 686
>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
sapiens]
Length = 1266
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 417 LFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEI 476
+FE L + Y+PQL+ ++++G IS W + F + + +++ D Y +++
Sbjct: 648 VFEELARDYVPQLYDCMQDLGVIS-TISLSWFLTLFLSVMPFESAVVVVDCFF-YEGIKV 705
Query: 477 LAVLAAAVFAFRAVNLMEVTSLAAAEAVL 505
+ LA AV L+ A VL
Sbjct: 706 IFQLALAVLDANVDKLLNCKDDGEAMTVL 734
>gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo
sapiens]
Length = 815
Score = 31.2 bits (69), Expect = 2.4
Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 4/62 (6%)
Query: 248 IRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTASNDD 307
++ G P ALRAE+W L+ + Y L I D +S+I +D+ T D
Sbjct: 535 VKSGVPEALRAEVWQLLAGCHDNQAMLDRYRIL----ITKDSAQESVITRDIHRTFPAHD 590
Query: 308 YY 309
Y+
Sbjct: 591 YF 592
>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
Length = 828
Score = 30.8 bits (68), Expect = 3.2
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 12/85 (14%)
Query: 248 IRQGSPTALRAELWALILNISSQPEDVL-YYEQLK-------TNVIQHDLLVDSLIYKDV 299
I +G P LR E+WAL+L I E+ Y +LK ++ Q DL V+ +
Sbjct: 97 IYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHI 156
Query: 300 KLTASNDDYYFVFEDYLYQVLLCFS 324
D Y V + L+ VL +S
Sbjct: 157 MFR----DRYGVKQQSLFHVLAAYS 177
>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
Length = 845
Score = 30.8 bits (68), Expect = 3.2
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 12/85 (14%)
Query: 248 IRQGSPTALRAELWALILNISSQPEDVL-YYEQLK-------TNVIQHDLLVDSLIYKDV 299
I +G P LR E+WAL+L I E+ Y +LK ++ Q DL V+ +
Sbjct: 114 IYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHI 173
Query: 300 KLTASNDDYYFVFEDYLYQVLLCFS 324
D Y V + L+ VL +S
Sbjct: 174 MFR----DRYGVKQQSLFHVLAAYS 194
>gi|38327034 ubiquitination factor E4B isoform 2 [Homo sapiens]
Length = 1173
Score = 30.8 bits (68), Expect = 3.2
Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 245 QQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLI--YKDVKLT 302
Q YIR A E+ + N + QP ++E ++ + + LLV SL+ Y DV+ T
Sbjct: 793 QNYIRNPYLVAKLVEVM-FMTNPAVQPRTQKFFEMIENHPLSTKLLVPSLMKFYTDVEHT 851
Query: 303 ASNDDYYFVF 312
+ ++Y F
Sbjct: 852 GATSEFYDKF 861
>gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]
Length = 1302
Score = 30.8 bits (68), Expect = 3.2
Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 3/70 (4%)
Query: 245 QQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLI--YKDVKLT 302
Q YIR A E+ + N + QP ++E ++ + + LLV SL+ Y DV+ T
Sbjct: 922 QNYIRNPYLVAKLVEVM-FMTNPAVQPRTQKFFEMIENHPLSTKLLVPSLMKFYTDVEHT 980
Query: 303 ASNDDYYFVF 312
+ ++Y F
Sbjct: 981 GATSEFYDKF 990
>gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens]
Length = 413
Score = 30.4 bits (67), Expect = 4.2
Identities = 26/107 (24%), Positives = 42/107 (39%), Gaps = 11/107 (10%)
Query: 418 FETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWD-------RILG 470
FE + LP+LF H ++ P W+ +S L D +WD L
Sbjct: 277 FEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLF 336
Query: 471 YNSLEILA----VLAAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKV 513
+L IL +L F A L + AE + A ++T+++
Sbjct: 337 RTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIATIQM 383
>gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 30.4 bits (67), Expect = 4.2
Identities = 26/107 (24%), Positives = 42/107 (39%), Gaps = 11/107 (10%)
Query: 418 FETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWD-------RILG 470
FE + LP+LF H ++ P W+ +S L D +WD L
Sbjct: 557 FEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLF 616
Query: 471 YNSLEILA----VLAAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKV 513
+L IL +L F A L + AE + A ++T+++
Sbjct: 617 RTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIATIQM 663
>gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 30.4 bits (67), Expect = 4.2
Identities = 26/107 (24%), Positives = 42/107 (39%), Gaps = 11/107 (10%)
Query: 418 FETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWD-------RILG 470
FE + LP+LF H ++ P W+ +S L D +WD L
Sbjct: 557 FEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLF 616
Query: 471 YNSLEILA----VLAAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKV 513
+L IL +L F A L + AE + A ++T+++
Sbjct: 617 RTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIATIQM 663
>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
isoform b [Homo sapiens]
Length = 1233
Score = 30.0 bits (66), Expect = 5.4
Identities = 17/68 (25%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Query: 417 LFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEI 476
+FE L + +LPQL ++++G IS W + F + + +++ D Y +++
Sbjct: 641 IFEELTRDFLPQLSEKMQDLGVIS-SISLSWFLTLFLSVMPFESAVVIVDCFF-YEGIKV 698
Query: 477 LAVLAAAV 484
+ +A AV
Sbjct: 699 ILQVALAV 706
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,536,714
Number of Sequences: 37866
Number of extensions: 886409
Number of successful extensions: 2059
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2031
Number of HSP's gapped (non-prelim): 49
length of query: 526
length of database: 18,247,518
effective HSP length: 107
effective length of query: 419
effective length of database: 14,195,856
effective search space: 5948063664
effective search space used: 5948063664
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.