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Search of human proteins with 157364937
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157364937 OTU domain containing 6B [Homo sapiens]
(323 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157364937 OTU domain containing 6B [Homo sapiens] 637 0.0
gi|46409282 OTU domain containing 6A [Homo sapiens] 320 8e-88
gi|149192871 OTU domain containing 3 [Homo sapiens] 63 4e-10
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 54 2e-07
gi|209977021 OTU domain containing 5 isoform b [Homo sapiens] 52 7e-07
gi|209977019 OTU domain containing 5 isoform b [Homo sapiens] 52 7e-07
gi|71061468 centromere protein E [Homo sapiens] 51 2e-06
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 50 2e-06
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 49 5e-06
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 49 5e-06
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] 49 8e-06
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens] 49 8e-06
gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens] 49 8e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 48 1e-05
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 48 1e-05
gi|33457350 OTU domain containing 5 isoform a [Homo sapiens] 47 2e-05
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 47 3e-05
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 46 5e-05
gi|31982906 cingulin-like 1 [Homo sapiens] 46 5e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 45 7e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 45 7e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 45 7e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 45 7e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 45 9e-05
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 9e-05
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 45 9e-05
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 45 9e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 45 1e-04
gi|148746195 trichohyalin [Homo sapiens] 45 1e-04
gi|55770834 centromere protein F [Homo sapiens] 45 1e-04
>gi|157364937 OTU domain containing 6B [Homo sapiens]
Length = 323
Score = 637 bits (1643), Expect = 0.0
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 1 MEPRVRVEGWKVPTSRCRFLLARVLGYLVVMEAVLTEELDEEEQLLRRHRKEKKELQAKI 60
MEPRVRVEGWKVPTSRCRFLLARVLGYLVVMEAVLTEELDEEEQLLRRHRKEKKELQAKI
Sbjct: 1 MEPRVRVEGWKVPTSRCRFLLARVLGYLVVMEAVLTEELDEEEQLLRRHRKEKKELQAKI 60
Query: 61 QGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLV 120
QGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLV
Sbjct: 61 QGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLV 120
Query: 121 LENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIK 180
LENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIK
Sbjct: 121 LENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIK 180
Query: 181 QIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPE 240
QIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPE
Sbjct: 181 QIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPE 240
Query: 241 EFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPIIVGEEYSKKPLILVYMRH 300
EFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPIIVGEEYSKKPLILVYMRH
Sbjct: 241 EFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPIIVGEEYSKKPLILVYMRH 300
Query: 301 AYGLGEHYNSVTRLVNIVTENCS 323
AYGLGEHYNSVTRLVNIVTENCS
Sbjct: 301 AYGLGEHYNSVTRLVNIVTENCS 323
>gi|46409282 OTU domain containing 6A [Homo sapiens]
Length = 288
Score = 320 bits (821), Expect = 8e-88
Identities = 156/275 (56%), Positives = 218/275 (79%), Gaps = 7/275 (2%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQL 100
E++++LRRH++E++ELQA+I+ +KN+VPK DK +RKQL +DVA++E EM QKHR+ELE+
Sbjct: 7 EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKF 66
Query: 101 KLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEI-ENLTG 159
+ ++ I+SV +++ + LEN+PPR SKA ++RE+ + E+ER+E I +AE+ E+L G
Sbjct: 67 Q---DDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAG 123
Query: 160 ARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQS 219
+ E EKLA IL AR LE+K IP+DGHCMY+AI+DQL +++V LR +TA YM+
Sbjct: 124 FKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLV---FSVSVEMLRCRTASYMKK 180
Query: 220 HVEDFLPFLTNPNTGDMYTPEEFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADS 279
HV++FLPF +NP T D + ++F YC++IV T AWGGQLELRALSH+L+TPIE+IQADS
Sbjct: 181 HVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADS 240
Query: 280 PPIIVGEEYSKKPLILVYMRHAYGLGEHYNSVTRL 314
P +I+GEEY KKP+ILVY+R+AY LGEHYNSVT L
Sbjct: 241 PTLIIGEEYVKKPIILVYLRYAYSLGEHYNSVTPL 275
>gi|149192871 OTU domain containing 3 [Homo sapiens]
Length = 398
Score = 62.8 bits (151), Expect = 4e-10
Identities = 52/190 (27%), Positives = 92/190 (48%), Gaps = 18/190 (9%)
Query: 127 RISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDG 186
R ++A+++R+++AA +ER E G E A L A L+++++P DG
Sbjct: 16 RKAEAERKRDERAARRALAKERRNRPESGGGGGCEE-EFVSFANQLQALGLKLREVPGDG 74
Query: 187 HCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPEEFQKYC 246
+C+++A+ DQL+ + + R +T +YM EDF PF+ + F+K+
Sbjct: 75 NCLFRALGDQLEGH--SRNHLKHRQETVDYMIKQREDFEPFVED--------DIPFEKHV 124
Query: 247 EDIVNTAAWGGQLELRALSHILQTPIEIIQADSP--PIIVGEEYSKKPLILVYMRHAYGL 304
+ + G + A + Q + I Q ++P I E+ S + L + AY
Sbjct: 125 ASLAKPGTFAGNDAIVAFARNHQLNVVIHQLNAPLWQIRGTEKSSVRELHI-----AYRY 179
Query: 305 GEHYNSVTRL 314
GEHY+SV R+
Sbjct: 180 GEHYDSVRRI 189
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 53.9 bits (128), Expect = 2e-07
Identities = 45/156 (28%), Positives = 85/156 (54%), Gaps = 19/156 (12%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLE---KEMEQ 91
L +E+D+ E +L + KEK+ + K++ + V + L ED++KL K +++
Sbjct: 962 LKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEV--------EFLNEDISKLNRAAKVVQE 1013
Query: 92 KHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAE 151
H++ L+ L + +E K+ S++ +NL LE Q + A + +E+KA + ERE E
Sbjct: 1014 AHQQTLDDLHM--EEEKLSSLSK--ANLKLEQQVDELEGALE-QERKARMNCERELHKLE 1068
Query: 152 AEIE-NLTGARHMESEK--LAQILAARQLEIKQIPS 184
++ N ++ES + LA+ L ++LE+ Q+ S
Sbjct: 1069 GNLKLNRESMENLESSQRHLAEELRKKELELSQMNS 1104
Score = 45.8 bits (107), Expect = 5e-05
Identities = 51/217 (23%), Positives = 98/217 (45%), Gaps = 26/217 (11%)
Query: 36 TEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKK---RRKQLTEDVAKLEKEMEQK 92
T+ L E E++ + +EK E+Q ++ + A+ +N+ K + +L E A+LE+++ +K
Sbjct: 1532 TKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEK 1591
Query: 93 HREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEA 152
EE+E + ++ IDS+ ++ + K R + L+K+ EE + E
Sbjct: 1592 D-EEIENFR-RKQQCTIDSLQSSLDS------------EAKSRIEVTRLKKKMEEDLNEM 1637
Query: 153 EIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQ 212
E++ L+ A SE + L Q++IK + ++D + VA+ +
Sbjct: 1638 ELQ-LSCANRQVSE-ATKSLGQLQIQIKDLQMQ-------LDDSTQLNSDLKEQVAVAER 1688
Query: 213 TAEYMQSHVEDFLPFLTNPNTGDMYTPEEFQKYCEDI 249
+QS +ED G + EE + E I
Sbjct: 1689 RNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERI 1725
Score = 45.4 bits (106), Expect = 7e-05
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 22/188 (11%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQ------LTEDVAKLEKE 88
+ +++ E+ L+ + +K KELQ +I+ +K + R K LT+D+A L +
Sbjct: 1102 MNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNER 1161
Query: 89 MEQKHREELEQLKLTTK-ENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREE 147
+E+ L QL++T K E K + ++ L + S ++ + A L
Sbjct: 1162 LEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAEL------ 1215
Query: 148 RIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVV 207
E ++ENL + +KL + + QLE+ + + M +A + EK C L
Sbjct: 1216 ---EGQVENLQQVK----QKLEKDKSDLQLEVDDLLTRVEQMTRAKAN--AEKLCTLYEE 1266
Query: 208 ALRSQTAE 215
L TA+
Sbjct: 1267 RLHEATAK 1274
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/156 (26%), Positives = 74/156 (47%), Gaps = 19/156 (12%)
Query: 33 AVLTEELDE----EEQLLRRHRKEKKELQAKIQGMKNAVPKNDK--KRRKQLTEDVAKLE 86
++L EL++ +EQ R R ++EL + + +N ++K+L DVA+++
Sbjct: 1691 SLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQ 1750
Query: 87 KEMEQKHREELEQLKLTTKENKIDSVAVNISNLV--LENQPPRISKAQKRREKKAALEKE 144
KE E+ +E E K A+ +NL L+ + I+ ++ RE +
Sbjct: 1751 KEAEEVVQE------CQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITD 1804
Query: 145 REERIAEAEIENLTGARHMESEKLAQILAARQLEIK 180
++R+AEAE L G+R K Q L +R E++
Sbjct: 1805 LQKRLAEAEQMALMGSR-----KQIQKLESRVRELE 1835
Score = 32.3 bits (72), Expect = 0.58
Identities = 36/160 (22%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 39 LDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKE----MEQKHR 94
L+E+E L+ + +EK +I+ ++ + K + K + L + K +++ EQ
Sbjct: 1303 LEEKEALINQLSREKSNFTRQIEDLRGQLEK-ETKSQSALAHALQKAQRDCDLLREQYEE 1361
Query: 95 EELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREER--IAEA 152
E+ + +L +K+++ V N R + +++ A +E E +A A
Sbjct: 1362 EQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANA 1421
Query: 153 EIENLTGARHMESEKLAQIL--------AARQLEIKQIPS 184
+L ARH +L L AA +L+ KQ+ S
Sbjct: 1422 RNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQS 1461
>gi|209977021 OTU domain containing 5 isoform b [Homo sapiens]
Length = 566
Score = 52.0 bits (123), Expect = 7e-07
Identities = 45/184 (24%), Positives = 77/184 (41%), Gaps = 22/184 (11%)
Query: 133 KRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQ--ILAARQLEIKQIPSDGHCMY 190
+R E A E E A A IE + A + E + + + IKQ+ DG C++
Sbjct: 167 EREEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKKGFIIKQMKEDGACLF 226
Query: 191 KAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPEEFQKYCEDIV 250
+A+ DQ+ E ++ H D+L + N + Y E+F Y
Sbjct: 227 RAVADQVYGDQ----------DMHEVVRKHCMDYL--MKNADYFSNYVTEDFTTYINRKR 274
Query: 251 NTAAWGGQLELRALSHILQTPIEIIQADSPPIIVG---EEYSKKPLILVYMRHAYGLGEH 307
G +E++A++ + P+E+ Q + PI + +P+ + Y R+ H
Sbjct: 275 KNNCHGNHIEMQAMAEMYNRPVEVYQYSTEPINTFHGIHQNEDEPIRVSYHRNI-----H 329
Query: 308 YNSV 311
YNSV
Sbjct: 330 YNSV 333
>gi|209977019 OTU domain containing 5 isoform b [Homo sapiens]
Length = 566
Score = 52.0 bits (123), Expect = 7e-07
Identities = 45/184 (24%), Positives = 77/184 (41%), Gaps = 22/184 (11%)
Query: 133 KRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQ--ILAARQLEIKQIPSDGHCMY 190
+R E A E E A A IE + A + E + + + IKQ+ DG C++
Sbjct: 167 EREEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKKGFIIKQMKEDGACLF 226
Query: 191 KAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPEEFQKYCEDIV 250
+A+ DQ+ E ++ H D+L + N + Y E+F Y
Sbjct: 227 RAVADQVYGDQ----------DMHEVVRKHCMDYL--MKNADYFSNYVTEDFTTYINRKR 274
Query: 251 NTAAWGGQLELRALSHILQTPIEIIQADSPPIIVG---EEYSKKPLILVYMRHAYGLGEH 307
G +E++A++ + P+E+ Q + PI + +P+ + Y R+ H
Sbjct: 275 KNNCHGNHIEMQAMAEMYNRPVEVYQYSTEPINTFHGIHQNEDEPIRVSYHRNI-----H 329
Query: 308 YNSV 311
YNSV
Sbjct: 330 YNSV 333
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 50.8 bits (120), Expect = 2e-06
Identities = 49/166 (29%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 21 LARVLGYLVVMEAVLTE---ELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQ 77
L+R L +E L E +L E++Q L ++E E+Q KI ++N KN+ K ++
Sbjct: 1115 LSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENL--KNELKNKEL 1172
Query: 78 LTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREK 137
E + E+ QK E E++K TKE K+ + L + R RE
Sbjct: 1173 TLEHMETERLELAQKLNENYEEVKSITKERKV------LKELQKSFETERDHLRGYIREI 1226
Query: 138 KA-ALEKEREERIAEAEI----ENLTGARHMESEKLAQILAARQLE 178
+A L+ + E +IA + E + R SEK AQI+ + LE
Sbjct: 1227 EATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLE 1272
Score = 45.1 bits (105), Expect = 9e-05
Identities = 45/191 (23%), Positives = 82/191 (42%), Gaps = 31/191 (16%)
Query: 38 ELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEME------- 90
++ EE ++ H KE++E K++G+ + +K L AKL+++++
Sbjct: 1771 KIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEH 1830
Query: 91 ------------QKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKK 138
QK E+EQLK K+ ++ +S L +EN ++ AQK E
Sbjct: 1831 QLITLKKDVNETQKKVSEMEQLKKQIKDQ-----SLTLSKLEIEN----LNLAQKLHENL 1881
Query: 139 AALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCM---YKAIED 195
++ +ER +E + ++ Q AR LEI+Q + +K D
Sbjct: 1882 EEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVD 1941
Query: 196 QLKEKDCALTV 206
+L+EK T+
Sbjct: 1942 KLREKISEKTI 1952
Score = 36.2 bits (82), Expect = 0.040
Identities = 54/220 (24%), Positives = 93/220 (42%), Gaps = 55/220 (25%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHR 94
L++ L E ++ KEK +LQ + +++ QL E++ KE+ KH
Sbjct: 1426 LSKRLQESHDEMKSVAKEKDDLQRLQEVLQS--------ESDQLKENI----KEIVAKHL 1473
Query: 95 EELEQLK-----LTTKENKIDSVAVNIS----------------NLVLENQPPRISKAQK 133
E E+LK L +E I+ + VN+S N L+N+ I + ++
Sbjct: 1474 ETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEE 1533
Query: 134 R---------REKKAALEKEREERIA--------EAEIENLTGARHMESEKLAQILAARQ 176
+ +EK L++ +E R A E+++ LT R ES++ QI+ +
Sbjct: 1534 QFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTN-RLQESQEEIQIMIKEK 1592
Query: 177 LEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEY 216
E+K++ + DQLKE + SQ EY
Sbjct: 1593 EEMKRVQE----ALQIERDQLKENTKEIVAKMKESQEKEY 1628
Score = 33.9 bits (76), Expect = 0.20
Identities = 34/167 (20%), Positives = 83/167 (49%), Gaps = 8/167 (4%)
Query: 38 ELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREEL 97
E+ E+ L++ ++ +K + +Q +++ + + + ++ E ++++ E K +E
Sbjct: 1542 EVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEA 1601
Query: 98 EQLKLTT-KENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREE-RIAEAEIE 155
Q++ KEN + VA + E Q +++ + +EK +E +E+ + +E
Sbjct: 1602 LQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLE 1661
Query: 156 NLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLK-EKD 201
N+ E+ +L QIL E++ + + + +++E+ LK E+D
Sbjct: 1662 NI----ETENIRLTQILHENLEEMRSVTKERDDL-RSVEETLKVERD 1703
Score = 33.9 bits (76), Expect = 0.20
Identities = 47/208 (22%), Positives = 101/208 (48%), Gaps = 26/208 (12%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEK----EME 90
LT+ L E + +R KE+ +L++ + +K + + R+ +T D+ K E+ M
Sbjct: 1670 LTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMH 1729
Query: 91 QK-HREELEQLK--LTTKENKIDSVAVNI--SNLVLENQPPRI-----------SKAQKR 134
K H+E +++L+ ++ K N+I ++ ++ SN L+ Q +I + Q+
Sbjct: 1730 LKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQET 1789
Query: 135 REKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIE 194
+K + E+ ++++ + ++L + EK+ Q L A + ++ + D + K +
Sbjct: 1790 IDKLRGIVSEKTDKLSNMQ-KDLENSNAKLQEKI-QELKANEHQLITLKKDVNETQKKVS 1847
Query: 195 --DQLKE--KDCALTVVALRSQTAEYMQ 218
+QLK+ KD +LT+ L + Q
Sbjct: 1848 EMEQLKKQIKDQSLTLSKLEIENLNLAQ 1875
Score = 31.2 bits (69), Expect = 1.3
Identities = 54/272 (19%), Positives = 95/272 (34%), Gaps = 55/272 (20%)
Query: 21 LARVLGYLVVMEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTE 80
L ++ + V L EL + +LLR + K+LQ I K K D + E
Sbjct: 559 LKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIE 618
Query: 81 DVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRRE---- 136
D K+M+Q L + + K +S + NL L+ + ++ K+ E
Sbjct: 619 D----PKQMKQT----LFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQ 670
Query: 137 ---------KKAALEKEREERIAEAEIENLTGA--------------------------- 160
KK ++ E+E + A EI LT
Sbjct: 671 LYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELN 730
Query: 161 RHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQ-------LKEKDCALTVVALRSQT 213
+ +E + + E+K +PS+ + K I+D+ EKD + V +
Sbjct: 731 KEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESR 790
Query: 214 AEYMQSHVEDFLPFLTNPNTGDMYTPEEFQKY 245
+ + + L + T +EFQ +
Sbjct: 791 VQGLLEEIGKTKDDLATTQSNYKSTDQEFQNF 822
Score = 30.8 bits (68), Expect = 1.7
Identities = 30/104 (28%), Positives = 45/104 (43%), Gaps = 18/104 (17%)
Query: 51 KEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKID 110
K K ELQ KIQ ++ +K+L K + M K E+EQLK + +
Sbjct: 1963 KSKDELQKKIQELQ----------KKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLS 2012
Query: 111 SVAVNISNLVLENQPPRISKAQKRREKKAALEKEREE--RIAEA 152
+V + N L K + E+ + KER+E RI E+
Sbjct: 2013 MQSVRMDNFQL------TKKLHESLEEIRIVAKERDELRRIKES 2050
Score = 29.6 bits (65), Expect = 3.8
Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 3/69 (4%)
Query: 38 ELDEEEQLLRRHRKEKKELQAKIQ--GMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHRE 95
E+ +E LL+R+RKE +L+ +++ ++ +K + QL E+ L+K +K E
Sbjct: 337 EVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEK-IE 395
Query: 96 ELEQLKLTT 104
L ++ +T+
Sbjct: 396 NLTRMLVTS 404
Score = 29.3 bits (64), Expect = 4.9
Identities = 28/142 (19%), Positives = 61/142 (42%), Gaps = 7/142 (4%)
Query: 38 ELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREEL 97
E+ +E + R KE KE K++ + +K L + +L+K++++ ++EL
Sbjct: 1921 EIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKEL 1980
Query: 98 EQLKLT-------TKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIA 150
+ L++ K N+++ + L Q R+ Q ++ +LE+ R
Sbjct: 1981 QLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKE 2040
Query: 151 EAEIENLTGARHMESEKLAQIL 172
E+ + + ME ++ L
Sbjct: 2041 RDELRRIKESLKMERDQFIATL 2062
Score = 28.5 bits (62), Expect = 8.4
Identities = 29/150 (19%), Positives = 65/150 (43%), Gaps = 10/150 (6%)
Query: 76 KQLTEDVAKLEKEMEQKHR-EELEQLKLTTKENKIDSVAVNISNL--VLENQPPRISKAQ 132
+QL + ++E ++++K+ +E E L+ TK+++ + ISNL ++++ +
Sbjct: 515 EQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLE 574
Query: 133 KRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKA 192
K L +E+E++I + + +++S+KL I ++ I
Sbjct: 575 NELSSKVELLREKEDQIKKLQ-------EYIDSQKLENIKMDLSYSLESIEDPKQMKQTL 627
Query: 193 IEDQLKEKDCALTVVALRSQTAEYMQSHVE 222
+ + D LRS+ E + E
Sbjct: 628 FDAETVALDAKRESAFLRSENLELKEKMKE 657
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 50.4 bits (119), Expect = 2e-06
Identities = 40/163 (24%), Positives = 81/163 (49%), Gaps = 16/163 (9%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEK--EMEQKHR 94
+E +E ++ R +KE +EL+ + + + + K+R ++L + KLEK EQK
Sbjct: 293 KEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQL 352
Query: 95 EE---LEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAE 151
+E LE+ KL + + S+ + I+ L+ + ++ + +++ EK ++E R+ E
Sbjct: 353 QEKIKLEERKLLLAQRNLQSIRL-IAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQE 411
Query: 152 AEI-------ENLTGARHMESEKLAQILAARQLEIKQIPSDGH 187
AE+ E G + E E ++L+ + + + P D H
Sbjct: 412 AELRRVEEEKERALGLQRKERELRERLLS---ILLSKKPDDSH 451
Score = 35.0 bits (79), Expect = 0.090
Identities = 36/141 (25%), Positives = 69/141 (48%), Gaps = 27/141 (19%)
Query: 46 LRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELE-----QL 100
+++ + E+++LQ Q + ++KRR++ E+ + E E +QK EELE +
Sbjct: 268 IKKRQLERQKLQELEQ------QREEQKRREKEAEERQRAE-ERKQKELEELERERKREE 320
Query: 101 KLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREK-KAALEKEREERIAEAEIENLTG 159
KL +E K + + + QK+ EK +A +K+ +E+I E + L
Sbjct: 321 KLRKREQK--------------QRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLA 366
Query: 160 ARHMESEKLAQILAARQLEIK 180
R+++S +L L +R +K
Sbjct: 367 QRNLQSIRLIAELLSRAKAVK 387
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 49.3 bits (116), Expect = 5e-06
Identities = 29/120 (24%), Positives = 65/120 (54%), Gaps = 2/120 (1%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREE 96
EE ++LL++ ++E++E K K + +++RR+Q + + E+E ++ R E
Sbjct: 655 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 714
Query: 97 LEQLKLTTKENKIDSVAVNISNLVLENQPP-RISKAQKRREKKAALEKEREERIAEAEIE 155
E+ +L +E + + + + E + R+ K Q +RE + +KE ++R+AE +++
Sbjct: 715 QER-QLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 773
Score = 39.7 bits (91), Expect = 0.004
Identities = 38/143 (26%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 44 QLLRRHRKEKKELQAKIQGMKNAVPKNDKK---RRKQLTED--VAKLEKEMEQKHREELE 98
Q+ + K K+E A+ + K A K ++ RRKQ E + L++E E++ +EL
Sbjct: 605 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 664
Query: 99 QLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLT 158
Q K ++ ++ A L + + R + Q+RRE++ ++ RE+ E E +
Sbjct: 665 QKKKEEEQERLRKAA-EAKRLAEQREQER--REQERREQERREQERREQERREQERQLAE 721
Query: 159 GARHMESEKLAQILAARQLEIKQ 181
R E E+L A R+L+ ++
Sbjct: 722 QERRREQERLQ---AERELQERE 741
Score = 33.9 bits (76), Expect = 0.20
Identities = 34/144 (23%), Positives = 63/144 (43%), Gaps = 5/144 (3%)
Query: 74 RRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQK 133
RRK+ E + + + E +++ R E +LK + K+ + + E + K +
Sbjct: 546 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQ 605
Query: 134 RREKKAALEKEREERIAEAEIENLTGARHME--SEKLAQILAARQLEIKQIPSDGHCMYK 191
EK EK +EER+AE + + A+ ME + Q AR+L Q + +
Sbjct: 606 IDEKT---EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQE 662
Query: 192 AIEDQLKEKDCALTVVALRSQTAE 215
++ + +E+ L A + AE
Sbjct: 663 LLQKKKEEEQERLRKAAEAKRLAE 686
Score = 29.3 bits (64), Expect = 4.9
Identities = 22/99 (22%), Positives = 50/99 (50%), Gaps = 7/99 (7%)
Query: 37 EELDEEEQLL---RRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKH 93
E ++E QL RR +E+ + + ++Q + A+ + +++QL ++ + +K+ EQ+
Sbjct: 711 ERREQERQLAEQERRREQERLQAERELQEREKAL----RLQKEQLQRELEEKKKKEEQQR 766
Query: 94 REELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQ 132
E + + K+ K + A N+ ++ Q P + Q
Sbjct: 767 LAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQ 805
Score = 28.5 bits (62), Expect = 8.4
Identities = 25/120 (20%), Positives = 54/120 (45%), Gaps = 22/120 (18%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPK--NDKKRRKQLTEDVAKLEKEMEQK 92
L E+ ++E + R +E++E + + Q + + ++RR+Q + +E E+
Sbjct: 684 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 743
Query: 93 HREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEA 152
R + EQL+ +E K K +++R + L++E+E++ EA
Sbjct: 744 LRLQKEQLQRELEEKK--------------------KKEEQQRLAERQLQEEQEKKAKEA 783
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 49.3 bits (116), Expect = 5e-06
Identities = 29/120 (24%), Positives = 65/120 (54%), Gaps = 2/120 (1%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREE 96
EE ++LL++ ++E++E K K + +++RR+Q + + E+E ++ R E
Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 710
Query: 97 LEQLKLTTKENKIDSVAVNISNLVLENQPP-RISKAQKRREKKAALEKEREERIAEAEIE 155
E+ +L +E + + + + E + R+ K Q +RE + +KE ++R+AE +++
Sbjct: 711 QER-QLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769
Score = 39.7 bits (91), Expect = 0.004
Identities = 38/143 (26%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 44 QLLRRHRKEKKELQAKIQGMKNAVPKNDKK---RRKQLTED--VAKLEKEMEQKHREELE 98
Q+ + K K+E A+ + K A K ++ RRKQ E + L++E E++ +EL
Sbjct: 601 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 660
Query: 99 QLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLT 158
Q K ++ ++ A L + + R + Q+RRE++ ++ RE+ E E +
Sbjct: 661 QKKKEEEQERLRKAA-EAKRLAEQREQER--REQERREQERREQERREQERREQERQLAE 717
Query: 159 GARHMESEKLAQILAARQLEIKQ 181
R E E+L A R+L+ ++
Sbjct: 718 QERRREQERLQ---AERELQERE 737
Score = 33.9 bits (76), Expect = 0.20
Identities = 34/144 (23%), Positives = 63/144 (43%), Gaps = 5/144 (3%)
Query: 74 RRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQK 133
RRK+ E + + + E +++ R E +LK + K+ + + E + K +
Sbjct: 542 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQ 601
Query: 134 RREKKAALEKEREERIAEAEIENLTGARHME--SEKLAQILAARQLEIKQIPSDGHCMYK 191
EK EK +EER+AE + + A+ ME + Q AR+L Q + +
Sbjct: 602 IDEKT---EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQE 658
Query: 192 AIEDQLKEKDCALTVVALRSQTAE 215
++ + +E+ L A + AE
Sbjct: 659 LLQKKKEEEQERLRKAAEAKRLAE 682
Score = 29.3 bits (64), Expect = 4.9
Identities = 22/99 (22%), Positives = 50/99 (50%), Gaps = 7/99 (7%)
Query: 37 EELDEEEQLL---RRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKH 93
E ++E QL RR +E+ + + ++Q + A+ + +++QL ++ + +K+ EQ+
Sbjct: 707 ERREQERQLAEQERRREQERLQAERELQEREKAL----RLQKEQLQRELEEKKKKEEQQR 762
Query: 94 REELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQ 132
E + + K+ K + A N+ ++ Q P + Q
Sbjct: 763 LAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQ 801
Score = 28.5 bits (62), Expect = 8.4
Identities = 25/120 (20%), Positives = 54/120 (45%), Gaps = 22/120 (18%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPK--NDKKRRKQLTEDVAKLEKEMEQK 92
L E+ ++E + R +E++E + + Q + + ++RR+Q + +E E+
Sbjct: 680 LAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 739
Query: 93 HREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEA 152
R + EQL+ +E K K +++R + L++E+E++ EA
Sbjct: 740 LRLQKEQLQRELEEKK--------------------KKEEQQRLAERQLQEEQEKKAKEA 779
>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 48.5 bits (114), Expect = 8e-06
Identities = 49/191 (25%), Positives = 92/191 (48%), Gaps = 30/191 (15%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKND--KKRRKQLTEDVAKLEKEMEQ--- 91
+EL + + LR E + L+ ++ G+KN K K++ + TE+ L+ +++Q
Sbjct: 679 QELKDVQDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSY 738
Query: 92 -KHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRRE------KKAALEKE 144
K +EEL+ LK T +E S L+N KA+++ E K A E+E
Sbjct: 739 HKQQEELDALKKTIEE----------SEETLKNTKEIQRKAEEKYEVLENKMKNAEAERE 788
Query: 145 REERIAEAEIENLTGARHMESEKL---AQILAARQLEIKQIPSDGHCMYK----AIEDQL 197
RE + A+ +++ S+K+ Q + A LE++++ + H YK A+ + +
Sbjct: 789 RELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKRE-HTSYKQQLEAVNEAI 847
Query: 198 KEKDCALTVVA 208
K + + V+A
Sbjct: 848 KSYESQIEVMA 858
Score = 38.5 bits (88), Expect = 0.008
Identities = 35/133 (26%), Positives = 66/133 (49%), Gaps = 7/133 (5%)
Query: 48 RHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKE- 106
R +E KE+Q K+ ++ + +NDKK K L ++ +LEK +++ L L+ E
Sbjct: 248 RSAEELKEMQDKVIKLQEELSENDKK-IKALNHEIEELEKRKDKETGGILRSLEDALAEA 306
Query: 107 NKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHM--- 163
++++ + + +L +N SK ++ +K +E + E E++ +T H
Sbjct: 307 QRVNTKSQSAFDLKKKNLACEESK--RKELEKNMVEDSKTLAAKEKEVKKITDGLHALQE 364
Query: 164 ESEKLAQILAARQ 176
S K A+ LAA Q
Sbjct: 365 ASNKDAEALAAAQ 377
Score = 33.5 bits (75), Expect = 0.26
Identities = 35/166 (21%), Positives = 76/166 (45%), Gaps = 34/166 (20%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLE-------- 86
L + ++E E+ L+ ++ +++ + K + ++N + + +R ++L + KL+
Sbjct: 748 LKKTIEESEETLKNTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKLDCAKTKADA 807
Query: 87 --KEMEQKHRE------ELEQLKLTTKENKIDSVAVNISNLVLENQ-----------PPR 127
K+M++K +E ELE+LK K AVN + E+Q
Sbjct: 808 SSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKES 867
Query: 128 ISKAQKR--REKKAALEKEREERIAEAEIENLTGARHMESEKLAQI 171
++KAQ+ ++K+ ++ + AE+ A+H E +Q+
Sbjct: 868 VNKAQEEVTKQKEVITAQDTVIKAKYAEV-----AKHKEQNNDSQL 908
>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 48.5 bits (114), Expect = 8e-06
Identities = 49/191 (25%), Positives = 92/191 (48%), Gaps = 30/191 (15%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKND--KKRRKQLTEDVAKLEKEMEQ--- 91
+EL + + LR E + L+ ++ G+KN K K++ + TE+ L+ +++Q
Sbjct: 679 QELKDVQDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSY 738
Query: 92 -KHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRRE------KKAALEKE 144
K +EEL+ LK T +E S L+N KA+++ E K A E+E
Sbjct: 739 HKQQEELDALKKTIEE----------SEETLKNTKEIQRKAEEKYEVLENKMKNAEAERE 788
Query: 145 REERIAEAEIENLTGARHMESEKL---AQILAARQLEIKQIPSDGHCMYK----AIEDQL 197
RE + A+ +++ S+K+ Q + A LE++++ + H YK A+ + +
Sbjct: 789 RELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKRE-HTSYKQQLEAVNEAI 847
Query: 198 KEKDCALTVVA 208
K + + V+A
Sbjct: 848 KSYESQIEVMA 858
Score = 38.5 bits (88), Expect = 0.008
Identities = 35/133 (26%), Positives = 66/133 (49%), Gaps = 7/133 (5%)
Query: 48 RHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKE- 106
R +E KE+Q K+ ++ + +NDKK K L ++ +LEK +++ L L+ E
Sbjct: 248 RSAEELKEMQDKVIKLQEELSENDKK-IKALNHEIEELEKRKDKETGGILRSLEDALAEA 306
Query: 107 NKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHM--- 163
++++ + + +L +N SK ++ +K +E + E E++ +T H
Sbjct: 307 QRVNTKSQSAFDLKKKNLACEESK--RKELEKNMVEDSKTLAAKEKEVKKITDGLHALQE 364
Query: 164 ESEKLAQILAARQ 176
S K A+ LAA Q
Sbjct: 365 ASNKDAEALAAAQ 377
Score = 33.5 bits (75), Expect = 0.26
Identities = 35/166 (21%), Positives = 76/166 (45%), Gaps = 34/166 (20%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLE-------- 86
L + ++E E+ L+ ++ +++ + K + ++N + + +R ++L + KL+
Sbjct: 748 LKKTIEESEETLKNTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKLDCAKTKADA 807
Query: 87 --KEMEQKHRE------ELEQLKLTTKENKIDSVAVNISNLVLENQ-----------PPR 127
K+M++K +E ELE+LK K AVN + E+Q
Sbjct: 808 SSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKES 867
Query: 128 ISKAQKR--REKKAALEKEREERIAEAEIENLTGARHMESEKLAQI 171
++KAQ+ ++K+ ++ + AE+ A+H E +Q+
Sbjct: 868 VNKAQEEVTKQKEVITAQDTVIKAKYAEV-----AKHKEQNNDSQL 908
>gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 48.5 bits (114), Expect = 8e-06
Identities = 49/191 (25%), Positives = 92/191 (48%), Gaps = 30/191 (15%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKND--KKRRKQLTEDVAKLEKEMEQ--- 91
+EL + + LR E + L+ ++ G+KN K K++ + TE+ L+ +++Q
Sbjct: 679 QELKDVQDELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSY 738
Query: 92 -KHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRRE------KKAALEKE 144
K +EEL+ LK T +E S L+N KA+++ E K A E+E
Sbjct: 739 HKQQEELDALKKTIEE----------SEETLKNTKEIQRKAEEKYEVLENKMKNAEAERE 788
Query: 145 REERIAEAEIENLTGARHMESEKL---AQILAARQLEIKQIPSDGHCMYK----AIEDQL 197
RE + A+ +++ S+K+ Q + A LE++++ + H YK A+ + +
Sbjct: 789 RELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKRE-HTSYKQQLEAVNEAI 847
Query: 198 KEKDCALTVVA 208
K + + V+A
Sbjct: 848 KSYESQIEVMA 858
Score = 38.5 bits (88), Expect = 0.008
Identities = 35/133 (26%), Positives = 66/133 (49%), Gaps = 7/133 (5%)
Query: 48 RHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKE- 106
R +E KE+Q K+ ++ + +NDKK K L ++ +LEK +++ L L+ E
Sbjct: 248 RSAEELKEMQDKVIKLQEELSENDKK-IKALNHEIEELEKRKDKETGGILRSLEDALAEA 306
Query: 107 NKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHM--- 163
++++ + + +L +N SK ++ +K +E + E E++ +T H
Sbjct: 307 QRVNTKSQSAFDLKKKNLACEESK--RKELEKNMVEDSKTLAAKEKEVKKITDGLHALQE 364
Query: 164 ESEKLAQILAARQ 176
S K A+ LAA Q
Sbjct: 365 ASNKDAEALAAAQ 377
Score = 33.5 bits (75), Expect = 0.26
Identities = 35/166 (21%), Positives = 76/166 (45%), Gaps = 34/166 (20%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLE-------- 86
L + ++E E+ L+ ++ +++ + K + ++N + + +R ++L + KL+
Sbjct: 748 LKKTIEESEETLKNTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKLDCAKTKADA 807
Query: 87 --KEMEQKHRE------ELEQLKLTTKENKIDSVAVNISNLVLENQ-----------PPR 127
K+M++K +E ELE+LK K AVN + E+Q
Sbjct: 808 SSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKES 867
Query: 128 ISKAQKR--REKKAALEKEREERIAEAEIENLTGARHMESEKLAQI 171
++KAQ+ ++K+ ++ + AE+ A+H E +Q+
Sbjct: 868 VNKAQEEVTKQKEVITAQDTVIKAKYAEV-----AKHKEQNNDSQL 908
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 48.1 bits (113), Expect = 1e-05
Identities = 50/202 (24%), Positives = 97/202 (48%), Gaps = 21/202 (10%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDV---AKLEKEMEQ 91
L ++EEE+ + + EKK++Q IQ ++ + + + R+K E V AKL+K E+
Sbjct: 920 LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979
Query: 92 KHREELEQLKLTTKENKI--DSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERI 149
+ E + KL KE K+ D +A +NL E + + K + K A+ + EER+
Sbjct: 980 QIILEDQNCKL-AKEKKLLEDRIAEFTTNLTEEEE--KSKSLAKLKNKHEAMITDLEERL 1036
Query: 150 AEAEIE---------NLTGARHMESEKLAQI---LAARQLEIKQIPSDGHCMYKAIEDQL 197
E + L G S+++A++ +A ++++ + + +E++
Sbjct: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096
Query: 198 KEKDCALTVV-ALRSQTAEYMQ 218
+K+ AL + L SQ +E +
Sbjct: 1097 AQKNMALKKIRELESQISELQE 1118
Score = 38.9 bits (89), Expect = 0.006
Identities = 42/152 (27%), Positives = 72/152 (47%), Gaps = 18/152 (11%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDV-AKLEKEME---QK 92
E+L+EEE+ K+ L A++ MK + D + E+V KL+K++E Q+
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKKM--EDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 93 HRE------ELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKERE 146
H E +LE+ K T + ++D + V++ + + K QK+ ++ A EK
Sbjct: 1401 HEEKVAAYDKLEKTK-TRLQQELDDLLVDLDH--QRQSACNLEKKQKKFDQLLAEEKTIS 1457
Query: 147 ERIAEAEIENLTGARHMESEKLAQILAARQLE 178
+ AE AR E++ L+ AR LE
Sbjct: 1458 AKYAEERDRAEAEAREKETKALS---LARALE 1486
Score = 37.4 bits (85), Expect = 0.018
Identities = 28/111 (25%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREE---L 97
+ E ++ ++ KEL+ K+Q M+ V K L +A+LE++++ + +E
Sbjct: 1775 KNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAAC 1834
Query: 98 EQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKR-REKKAALEKEREE 147
+Q++ T K+ K + V+ E + KA R ++ K LE+ EE
Sbjct: 1835 KQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEE 1885
Score = 35.8 bits (81), Expect = 0.053
Identities = 42/162 (25%), Positives = 73/162 (45%), Gaps = 21/162 (12%)
Query: 38 ELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKN-------DKKRRKQLTEDVAKLEKEME 90
+L+E E L+ K L+ +Q MK ++ ++++KQL V ++E E+E
Sbjct: 1540 QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELE 1599
Query: 91 QKH---------REELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAAL 141
+ R++LE + L E IDS N + + + + RE
Sbjct: 1600 DERKQRSMAVAARKKLE-MDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT- 1657
Query: 142 EKEREERIAEAEIENLTGARHMESE--KLAQILAARQLEIKQ 181
REE +A+A+ EN + ME+E +L + LAA + +Q
Sbjct: 1658 RASREEILAQAK-ENEKKLKSMEAEMIQLQEELAAAERAKRQ 1698
Score = 34.7 bits (78), Expect = 0.12
Identities = 39/191 (20%), Positives = 84/191 (43%), Gaps = 14/191 (7%)
Query: 33 AVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQK 92
A T L EEE+ + K K + +A I ++ + + ++K+R++L + KLE +
Sbjct: 1002 AEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL-RREEKQRQELEKTRRKLEGDSTDL 1060
Query: 93 HREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEA 152
+++ +L+ E K+ L + + A R E++AA + ++I E
Sbjct: 1061 -SDQIAELQAQIAELKMQ----------LAKKEEELQAALARVEEEAAQKNMALKKIREL 1109
Query: 153 EIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQ 212
E + +ESE+ ++ A +Q + + + + +ED L + + R Q
Sbjct: 1110 ESQISELQEDLESERASRNKAEKQK--RDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167
Query: 213 TAEYMQSHVED 223
++ +E+
Sbjct: 1168 EVNILKKTLEE 1178
Score = 34.3 bits (77), Expect = 0.15
Identities = 36/170 (21%), Positives = 75/170 (44%), Gaps = 30/170 (17%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKN---------AVPKNDKKRRKQ-------L 78
L E+L+ E + K+K++L +++ +K A + + +R+Q
Sbjct: 1116 LQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKT 1175
Query: 79 TEDVAKLEK----EMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKR 134
E+ AK + EM QKH + +E+L ++ K + + LEN+ + +
Sbjct: 1176 LEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENE-----RGELA 1230
Query: 135 REKKAAL----EKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIK 180
E K L + E + + EA+++ L + E E++ LA + +++
Sbjct: 1231 NEVKVLLQGKGDSEHKRKKVEAQLQELQ-VKFNEGERVRTELADKVTKLQ 1279
Score = 32.0 bits (71), Expect = 0.76
Identities = 34/189 (17%), Positives = 77/189 (40%), Gaps = 5/189 (2%)
Query: 39 LDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELE 98
L+++++ + E+K + AK ++ +++ + LE+ MEQK E
Sbjct: 1439 LEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERL 1498
Query: 99 QLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIE--- 155
+ T+ + S ++ V E + + + Q+ E K LE+ +E A + +
Sbjct: 1499 NKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRL 1558
Query: 156 --NLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQT 213
NL + L + + KQ+ M +ED+ K++ A+
Sbjct: 1559 EVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMD 1618
Query: 214 AEYMQSHVE 222
+ +++H++
Sbjct: 1619 LKDLEAHID 1627
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 47.8 bits (112), Expect = 1e-05
Identities = 49/214 (22%), Positives = 97/214 (45%), Gaps = 25/214 (11%)
Query: 21 LARVLGYLVVMEAVLTE-ELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDK----KRR 75
L R+ L+ M+A E L+E E+ K + +L+ K+ ++N + + +
Sbjct: 51 LFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDT 110
Query: 76 KQLTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRR 135
+ L ++ +LEK++EQK RE + K KE K++ L L N+ ++ RR
Sbjct: 111 RFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVN------EQLALRNEEAENENSKLRR 164
Query: 136 EKKAALEKERE--------ERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGH 187
E K +K + ++ +++ E L R +S+ +Q L+ + E+ Q +
Sbjct: 165 ENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQ-LSKKNYELIQYLDEIQ 223
Query: 188 CMYKA-----IEDQLKEKDCALTVVALRSQTAEY 216
+ +A +++Q K+ +V + T EY
Sbjct: 224 TLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEY 257
Score = 37.4 bits (85), Expect = 0.018
Identities = 31/125 (24%), Positives = 62/125 (49%), Gaps = 11/125 (8%)
Query: 37 EELDEEEQLLRRHRKEKKELQ-----AKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQ 91
+E+ E +Q+L R++ K Q + + ++ + + D + K LTE V + KEME
Sbjct: 322 DEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQGIQERDSQI-KMLTEQVEQYTKEME- 379
Query: 92 KHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAAL----EKEREE 147
K+ +E LK + NK S +++ +++ + + K E+ A L +E+++
Sbjct: 380 KNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDK 439
Query: 148 RIAEA 152
+ EA
Sbjct: 440 ELVEA 444
Score = 35.8 bits (81), Expect = 0.053
Identities = 44/180 (24%), Positives = 84/180 (46%), Gaps = 22/180 (12%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREE 96
+E + +E+L+R +E K+ QAKI+G++N + K + LT+ + L+ + +E+
Sbjct: 1901 KEKNAKEELIRW--EEGKKWQAKIEGIRNKL-KEKEGEVFTLTKQLNTLKDLFAKADKEK 1957
Query: 97 LE-QLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIE 155
L Q KL T +D V + I L E + + K E + + ++ +E
Sbjct: 1958 LTLQRKLKTTGMTVDQV-LGIRALESEKELEELKKRNLDLENDILYMRAHQALPRDSVVE 2016
Query: 156 NLTGARHMESEKLAQILAARQLE----------IKQIPSDGHCMYKAIEDQLKEKDCALT 205
+L H+++ L + L A + + I I SD HC E +L++++ L+
Sbjct: 2017 DL----HLQNRYLQEKLHALEKQFSKDTYSKPSISGIESDDHCQR---EQELQKENLKLS 2069
Score = 30.0 bits (66), Expect = 2.9
Identities = 39/189 (20%), Positives = 83/189 (43%), Gaps = 27/189 (14%)
Query: 36 TEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLE------KEM 89
TE++ E + LR+ K++ + K++ KN + ++K QL E +L+ ++
Sbjct: 2199 TEKIIAENERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQFAESRGPQL 2258
Query: 90 EQKHREELEQLKLTTK-ENKIDSVAVNIS--NLVLENQPPRISKAQKRREKKAALEKERE 146
E + + + +T E K+ + +I+ N + + + +A +R +K ++ E
Sbjct: 2259 EGADSKSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLE 2318
Query: 147 ERI---------------AEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYK 191
++I + E++ L A H ++ A+++ Q+E + S
Sbjct: 2319 QQIKILKHVPEGAETEQGLKRELQVLRLANHQLDKEKAELI--HQIEANKDQSGAESTIP 2376
Query: 192 AIEDQLKEK 200
DQLKEK
Sbjct: 2377 D-ADQLKEK 2384
Score = 28.9 bits (63), Expect = 6.5
Identities = 30/154 (19%), Positives = 70/154 (45%), Gaps = 11/154 (7%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREE 96
+ L++E LLR+ E + K + + + + E + L +E+E K ++
Sbjct: 741 DHLEKETSLLRQ--SEGSNVVFKGIDLPDGIAPSSASIINSQNEYLIHLLQELENKEKK- 797
Query: 97 LEQLKLTTKENKIDSVAVNISNLVL------ENQPPRISKAQKRREKKAALEKEREERIA 150
L+ L+ + ++ + +L E + + + EK+ ++ +++ I
Sbjct: 798 LKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIK 857
Query: 151 EAEIENLTGARHMESEKLAQILA--ARQLEIKQI 182
E NL A M+S+++ +ILA +R++ + Q+
Sbjct: 858 VKEYNNLLNALQMDSDEMKKILAENSRKITVLQV 891
>gi|33457350 OTU domain containing 5 isoform a [Homo sapiens]
Length = 571
Score = 47.0 bits (110), Expect = 2e-05
Identities = 45/189 (23%), Positives = 76/189 (40%), Gaps = 27/189 (14%)
Query: 133 KRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQ--ILAARQLEIKQIPSDGHCMY 190
+R E A E E A A IE + A + E + + + IKQ+ DG C++
Sbjct: 167 EREEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKKGFIIKQMKEDGACLF 226
Query: 191 KAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPEEFQKYCEDIV 250
+A+ DQ V E ++ H D+L + N + Y E+F Y
Sbjct: 227 RAVADQ----------VYGDQDMHEVVRKHCMDYL--MKNADYFSNYVTEDFTTYINRKR 274
Query: 251 NTAAWGGQLELRALSHILQTPIEIIQADSPPIIVG--------EEYSKKPLILVYMRHAY 302
G +E++A++ + P+E+ Q + V + +P+ + Y R+
Sbjct: 275 KNNCHGNHIEMQAMAEMYNRPVEVYQYSTGTSAVEPINTFHGIHQNEDEPIRVSYHRNI- 333
Query: 303 GLGEHYNSV 311
HYNSV
Sbjct: 334 ----HYNSV 338
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/209 (24%), Positives = 90/209 (43%), Gaps = 32/209 (15%)
Query: 23 RVLGYLVVMEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDV 82
R L L +VL +EL E + L R ++ LQA+ + A+ K + R +L +
Sbjct: 666 RQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGR-VELELSM 724
Query: 83 AKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALE 142
KL E E ++ L +L + D + +N LE + + Q++ E++A +
Sbjct: 725 TKLRAE-EASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVA 783
Query: 143 KEREERIAEAEIEN------------------------LTGARHMES---EKLAQI---L 172
+E +ER+ E +E L RH S E+LAQ+ L
Sbjct: 784 REEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQL 843
Query: 173 AARQLEIKQIPSDGHCMYKAIEDQLKEKD 201
+ R+ E++Q + +A+E +EK+
Sbjct: 844 SGREQELEQARREAQRQVEALERAAREKE 872
Score = 37.0 bits (84), Expect = 0.024
Identities = 48/222 (21%), Positives = 97/222 (43%), Gaps = 32/222 (14%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHR 94
L L +Q R+E+++LQA + ++ + ++++ + +D A++ +E+E+ HR
Sbjct: 608 LAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQ-EDAVQDGARVRRELERSHR 666
Query: 95 EELEQL--KLTTKENKIDSVAVNISNLVLENQPPRISKAQ-------------------- 132
+LEQL K + ++ V +S L+ + KA+
Sbjct: 667 -QLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMT 725
Query: 133 KRREKKAALE------KEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDG 186
K R ++A+L+ E +A+ +++ +E EK A L RQ + +Q +
Sbjct: 726 KLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSA--LQGRQRQAEQEATVA 783
Query: 187 HCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFL 228
+ +E+ E++ A + + AE Q +E LP L
Sbjct: 784 REEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTL 825
Score = 37.0 bits (84), Expect = 0.024
Identities = 33/163 (20%), Positives = 75/163 (46%), Gaps = 8/163 (4%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQ--KHREELE 98
E+E R E+ +LQ+++Q + + + +++L+E++A L++E ++ E +
Sbjct: 1001 EKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEK 1060
Query: 99 QLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLT 158
Q L+ KE+ + A++ + + IS +R+++ A +E++ A L
Sbjct: 1061 QQALSLKES--EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 1118
Query: 159 GARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKD 201
R E AA E++++ + K + L+E +
Sbjct: 1119 DLRAQREE----AAAAHAQEVRRLQEQARDLGKQRDSCLREAE 1157
Score = 31.6 bits (70), Expect = 1.00
Identities = 39/165 (23%), Positives = 68/165 (41%), Gaps = 20/165 (12%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKL-------EKEM 89
EEL E+++ R+ + + + Q + R QL E +A+L E+E+
Sbjct: 791 EELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQEL 850
Query: 90 EQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERI 149
EQ RE Q++ ++ A L E+ + RE + E+ R+
Sbjct: 851 EQARREAQRQVE------ALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRL 904
Query: 150 AEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIE 194
E E L G+ +LAQ+ A R+ Q+ ++G + A E
Sbjct: 905 ---EKEALEGSLFEVQRQLAQLEARRE----QLEAEGQALLLAKE 942
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 45.8 bits (107), Expect = 5e-05
Identities = 54/223 (24%), Positives = 103/223 (46%), Gaps = 20/223 (8%)
Query: 38 ELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREEL 97
+LD+E + R + E + QA+ + + + +++ + TED + E ++ +E+L
Sbjct: 12 KLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKL 71
Query: 98 EQLKLTTKENKIDSVAVN----ISNLVLENQPPRISKAQKRRE--KKAALEKEREERIAE 151
EQ + + + D ++N + L+ R++ A ++ E +KAA E ER ++
Sbjct: 72 EQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV-- 129
Query: 152 AEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRS 211
IEN R M+ E+ ++ + E K I D Y+ + +L + L R+
Sbjct: 130 --IEN----RAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERA 183
Query: 212 QTAEYMQSHVEDFLPFLTN-----PNTGDMYTPEEFQKYCEDI 249
+ AE +E+ L +TN D Y+ +E KY E+I
Sbjct: 184 EVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKE-DKYEEEI 225
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 45.8 bits (107), Expect = 5e-05
Identities = 49/223 (21%), Positives = 94/223 (42%), Gaps = 29/223 (13%)
Query: 6 RVEGWKVPTSRCRFLLARVLGYLVVMEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKN 65
++E K ++ + L + G + +E L EE++ + R + EL+A QG +
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEA-AQGNLS 909
Query: 66 AVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNI------SNL 119
+ K+ ++L E+ + E+ K+ E E+ L K+ +I S L
Sbjct: 910 QTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTL 969
Query: 120 VLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEI 179
L+NQ +K R + A ++++ +E+ EAE LT + + +L
Sbjct: 970 ELQNQLDEYK--EKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRL----------- 1016
Query: 180 KQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVE 222
M + + D + +D ALT L QT + ++ +E
Sbjct: 1017 ---------MEEELRDYQRAQDEALTKRQLLEQTLKDLEYELE 1050
Score = 38.9 bits (89), Expect = 0.006
Identities = 54/229 (23%), Positives = 101/229 (44%), Gaps = 26/229 (11%)
Query: 40 DEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQ 99
+E+E LL RK ++EL A +K V +D +++ KL+++ + + + E
Sbjct: 747 EEQEDLL---RKRERELTALKGALKEEVSSHD--------QEMDKLKEQYDAELQALRES 795
Query: 100 LKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIA--EAEIENL 157
++ TK ++ + N S R+ Q+ EK +E E R+A + +IE+L
Sbjct: 796 VEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDL 855
Query: 158 TGARHMESEKLAQILA-ARQLE-----IKQIPSDGHCMYKAIEDQLKEKDCALT-VVALR 210
G E L + RQLE ++ + +A+E++L+ L+ +
Sbjct: 856 KGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQ 915
Query: 211 SQTAEYM--QSHVEDFLPFLTNPNTGDMY----TPEEFQKYCEDIVNTA 253
Q +E + +S ++ L L N + + T E+ QK DIV +
Sbjct: 916 KQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEAS 964
Score = 35.8 bits (81), Expect = 0.053
Identities = 37/166 (22%), Positives = 71/166 (42%), Gaps = 20/166 (12%)
Query: 39 LDEEEQLLRRHRKEKK----ELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHR 94
L EE + L+ +E + +LQ +I+ +K K K+ K+ ++ +LE+ + +
Sbjct: 827 LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKA-KETLKKYEGEIRQLEEALVHARK 885
Query: 95 EELEQLKLTTK-ENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAE 153
EE E + EN++++ N+S Q +E+K EK +EE + +
Sbjct: 886 EEKEAVSARRALENELEAAQGNLS--------------QTTQEQKQLSEKLKEESEQKEQ 931
Query: 154 IENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKE 199
+ L E L + + Q E+ I +++QL E
Sbjct: 932 LRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDE 977
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 45.4 bits (106), Expect = 7e-05
Identities = 30/117 (25%), Positives = 62/117 (52%), Gaps = 6/117 (5%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQL 100
+ E ++ ++ KEL++K+ M+ AV K L +A+LE+++EQ+ RE+
Sbjct: 1782 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 1841
Query: 101 K-LTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIEN 156
K L K+ K+ + + + E++ + +++ EK A K+ + ++ EAE E+
Sbjct: 1842 KSLKQKDKKLKEILLQV-----EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES 1893
Score = 45.1 bits (105), Expect = 9e-05
Identities = 47/182 (25%), Positives = 84/182 (46%), Gaps = 36/182 (19%)
Query: 51 KEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKID 110
++++E+QAK ++ K R+Q E+ K E+EQKH + E+ L ++
Sbjct: 849 RQEEEMQAKEDELQKT------KERQQKAENELK---ELEQKHSQLTEEKNLLQEQ---- 895
Query: 111 SVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQ 170
L+ + ++A++ R + AA ++E EE + E E AR E E Q
Sbjct: 896 ----------LQAETELYAEAEEMRVRLAAKKQELEEILHEME------ARLEEEEDRGQ 939
Query: 171 ILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTN 230
L A + ++ Q D +E+QL+E++ A + L TAE +ED + + +
Sbjct: 940 QLQAERKKMAQQMLD-------LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDD 992
Query: 231 PN 232
N
Sbjct: 993 QN 994
Score = 42.7 bits (99), Expect = 4e-04
Identities = 48/162 (29%), Positives = 82/162 (50%), Gaps = 26/162 (16%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAV----PKNDK--KRRKQLTEDVAKLEKE 88
L E+L+EEE ++ + EK +AKI+ +++ + +N+K K RK L E ++ L
Sbjct: 955 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
Query: 89 MEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKERE-- 146
+ + EE + LT +NK +S+ IS L + R+ K +K R++ L+++ E
Sbjct: 1015 LAE---EEEKAKNLTKLKNKHESM---ISELEV-----RLKKEEKSRQELEKLKRKLEGD 1063
Query: 147 -----ERIA--EAEIENLTGARHMESEKLAQILAARQLEIKQ 181
E+IA +A+I L + E+L LA EI Q
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ 1105
Score = 36.2 bits (82), Expect = 0.040
Identities = 35/169 (20%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAV------PKNDKKRRKQLTEDVAKLEKE 88
L E+LD E + K+K++L +++ +K + ++ R + ++V L+K
Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA 1182
Query: 89 MEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREER 148
++++ R Q++ +++ A + L + + + +KA + K+ LEKE +
Sbjct: 1183 LDEETRSHEAQVQEMRQKH-----AQAVEELTEQLEQFKRAKANLDKNKQ-TLEKENADL 1236
Query: 149 IAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQL 197
E + G E E + L A+ E++ SDG + D++
Sbjct: 1237 AGELRV---LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Score = 35.8 bits (81), Expect = 0.053
Identities = 47/212 (22%), Positives = 97/212 (45%), Gaps = 35/212 (16%)
Query: 31 MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVA------K 84
MEA L EE D +QL + E+K++ ++ ++ + + + R+K E V K
Sbjct: 927 MEARLEEEEDRGQQL----QAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 85 LEKEM---------EQKHREELEQ--LKLTTKENKIDSVAVNISNLVLENQPPRISKAQK 133
LE E+ K R+ LE+ LTT + + A N++ L +++ IS+ +
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE-SMISELEV 1041
Query: 134 R--REKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYK 191
R +E+K+ E E+ +R E + + H + L +A ++++ + +
Sbjct: 1042 RLKKEEKSRQELEKLKRKLEGDASDF----HEQIADLQAQIAELKMQLAKKEEELQAALA 1097
Query: 192 AIEDQLKEKDCALTVVALRSQTAEYMQSHVED 223
++D++ +K+ AL + ++ H+ D
Sbjct: 1098 RLDDEIAQKNNALKKI-------RELEGHISD 1122
Score = 32.7 bits (73), Expect = 0.45
Identities = 40/194 (20%), Positives = 85/194 (43%), Gaps = 35/194 (18%)
Query: 40 DEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQ 99
D+ E+ R ++E +L + + V +KK+RK + + EK + K+ +E ++
Sbjct: 1416 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK--FDQLLAEEKNISSKYADERDR 1473
Query: 100 LKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENL-- 157
+ +E + ++++ + +A + +E E ER ++ +AE+E+L
Sbjct: 1474 AEAEAREKETKALSL----------ARALEEALEAKE-----ELERTNKMLKAEMEDLVS 1518
Query: 158 ----TGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCA-----LTVVA 208
G E EK + L + E+K + +ED+L+ + A + + A
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMK-------TQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 209 LRSQTAEYMQSHVE 222
L+ Q +Q+ E
Sbjct: 1572 LKGQFERDLQARDE 1585
Score = 32.7 bits (73), Expect = 0.45
Identities = 36/168 (21%), Positives = 80/168 (47%), Gaps = 16/168 (9%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHR 94
L E L+ +E+L R ++ K E++ + K+ V KN +L + LE +ME+ +
Sbjct: 1492 LEEALEAKEELERTNKMLKAEMEDLVSS-KDDVGKNVH----ELEKSKRALETQMEEM-K 1545
Query: 95 EELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEI 154
+LE+L+ + + + + ++ L+ Q R +A+ + ++ + +R+ E E+
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605
Query: 155 ENLTGARHMESEKLAQILAARQL---EIKQIPSDGHCMYKAIEDQLKE 199
E+ E ++ A AA++ ++K + K E+ +K+
Sbjct: 1606 ED-------ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646
Score = 30.0 bits (66), Expect = 2.9
Identities = 34/160 (21%), Positives = 76/160 (47%), Gaps = 15/160 (9%)
Query: 31 MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKN-------AVPKNDKKRRKQLTEDVA 83
ME + T+ L+E E L+ K L+ +Q +K A + ++++R+QL +
Sbjct: 1541 MEEMKTQ-LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1599
Query: 84 KLEKEMEQKHREELEQLKLTTK-ENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALE 142
+ E E+E + ++ K E + + + ++ ++ + I + +K + + +
Sbjct: 1600 EYETELEDERKQRALAAAAKKKLEGDLKDLELQ-ADSAIKGREEAIKQLRKLQAQMKDFQ 1658
Query: 143 KEREE-RIAEAEIENLTGARHMESEKLAQILAARQLEIKQ 181
+E E+ R + EI A E+EK A+ L A +++++
Sbjct: 1659 RELEDARASRDEI----FATAKENEKKAKSLEADLMQLQE 1694
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 45.4 bits (106), Expect = 7e-05
Identities = 30/117 (25%), Positives = 62/117 (52%), Gaps = 6/117 (5%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQL 100
+ E ++ ++ KEL++K+ M+ AV K L +A+LE+++EQ+ RE+
Sbjct: 1789 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 1848
Query: 101 K-LTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIEN 156
K L K+ K+ + + + E++ + +++ EK A K+ + ++ EAE E+
Sbjct: 1849 KSLKQKDKKLKEILLQV-----EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES 1900
Score = 45.1 bits (105), Expect = 9e-05
Identities = 47/182 (25%), Positives = 84/182 (46%), Gaps = 36/182 (19%)
Query: 51 KEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKID 110
++++E+QAK ++ K R+Q E+ K E+EQKH + E+ L ++
Sbjct: 856 RQEEEMQAKEDELQKT------KERQQKAENELK---ELEQKHSQLTEEKNLLQEQ---- 902
Query: 111 SVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQ 170
L+ + ++A++ R + AA ++E EE + E E AR E E Q
Sbjct: 903 ----------LQAETELYAEAEEMRVRLAAKKQELEEILHEME------ARLEEEEDRGQ 946
Query: 171 ILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTN 230
L A + ++ Q D +E+QL+E++ A + L TAE +ED + + +
Sbjct: 947 QLQAERKKMAQQMLD-------LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDD 999
Query: 231 PN 232
N
Sbjct: 1000 QN 1001
Score = 42.7 bits (99), Expect = 4e-04
Identities = 48/162 (29%), Positives = 82/162 (50%), Gaps = 26/162 (16%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAV----PKNDK--KRRKQLTEDVAKLEKE 88
L E+L+EEE ++ + EK +AKI+ +++ + +N+K K RK L E ++ L
Sbjct: 962 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1021
Query: 89 MEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKERE-- 146
+ + EE + LT +NK +S+ IS L + R+ K +K R++ L+++ E
Sbjct: 1022 LAE---EEEKAKNLTKLKNKHESM---ISELEV-----RLKKEEKSRQELEKLKRKLEGD 1070
Query: 147 -----ERIA--EAEIENLTGARHMESEKLAQILAARQLEIKQ 181
E+IA +A+I L + E+L LA EI Q
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ 1112
Score = 36.2 bits (82), Expect = 0.040
Identities = 35/169 (20%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAV------PKNDKKRRKQLTEDVAKLEKE 88
L E+LD E + K+K++L +++ +K + ++ R + ++V L+K
Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA 1189
Query: 89 MEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREER 148
++++ R Q++ +++ A + L + + + +KA + K+ LEKE +
Sbjct: 1190 LDEETRSHEAQVQEMRQKH-----AQAVEELTEQLEQFKRAKANLDKNKQ-TLEKENADL 1243
Query: 149 IAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQL 197
E + G E E + L A+ E++ SDG + D++
Sbjct: 1244 AGELRV---LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1289
Score = 35.8 bits (81), Expect = 0.053
Identities = 47/212 (22%), Positives = 97/212 (45%), Gaps = 35/212 (16%)
Query: 31 MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVA------K 84
MEA L EE D +QL + E+K++ ++ ++ + + + R+K E V K
Sbjct: 934 MEARLEEEEDRGQQL----QAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 989
Query: 85 LEKEM---------EQKHREELEQ--LKLTTKENKIDSVAVNISNLVLENQPPRISKAQK 133
LE E+ K R+ LE+ LTT + + A N++ L +++ IS+ +
Sbjct: 990 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE-SMISELEV 1048
Query: 134 R--REKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYK 191
R +E+K+ E E+ +R E + + H + L +A ++++ + +
Sbjct: 1049 RLKKEEKSRQELEKLKRKLEGDASDF----HEQIADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 192 AIEDQLKEKDCALTVVALRSQTAEYMQSHVED 223
++D++ +K+ AL + ++ H+ D
Sbjct: 1105 RLDDEIAQKNNALKKI-------RELEGHISD 1129
Score = 32.7 bits (73), Expect = 0.45
Identities = 40/194 (20%), Positives = 85/194 (43%), Gaps = 35/194 (18%)
Query: 40 DEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQ 99
D+ E+ R ++E +L + + V +KK+RK + + EK + K+ +E ++
Sbjct: 1423 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK--FDQLLAEEKNISSKYADERDR 1480
Query: 100 LKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENL-- 157
+ +E + ++++ + +A + +E E ER ++ +AE+E+L
Sbjct: 1481 AEAEAREKETKALSL----------ARALEEALEAKE-----ELERTNKMLKAEMEDLVS 1525
Query: 158 ----TGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCA-----LTVVA 208
G E EK + L + E+K + +ED+L+ + A + + A
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMK-------TQLEELEDELQATEDAKLRLEVNMQA 1578
Query: 209 LRSQTAEYMQSHVE 222
L+ Q +Q+ E
Sbjct: 1579 LKGQFERDLQARDE 1592
Score = 32.7 bits (73), Expect = 0.45
Identities = 36/168 (21%), Positives = 80/168 (47%), Gaps = 16/168 (9%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHR 94
L E L+ +E+L R ++ K E++ + K+ V KN +L + LE +ME+ +
Sbjct: 1499 LEEALEAKEELERTNKMLKAEMEDLVSS-KDDVGKNVH----ELEKSKRALETQMEEM-K 1552
Query: 95 EELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEI 154
+LE+L+ + + + + ++ L+ Q R +A+ + ++ + +R+ E E+
Sbjct: 1553 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1612
Query: 155 ENLTGARHMESEKLAQILAARQL---EIKQIPSDGHCMYKAIEDQLKE 199
E+ E ++ A AA++ ++K + K E+ +K+
Sbjct: 1613 ED-------ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1653
Score = 30.0 bits (66), Expect = 2.9
Identities = 34/160 (21%), Positives = 76/160 (47%), Gaps = 15/160 (9%)
Query: 31 MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKN-------AVPKNDKKRRKQLTEDVA 83
ME + T+ L+E E L+ K L+ +Q +K A + ++++R+QL +
Sbjct: 1548 MEEMKTQ-LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 84 KLEKEMEQKHREELEQLKLTTK-ENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALE 142
+ E E+E + ++ K E + + + ++ ++ + I + +K + + +
Sbjct: 1607 EYETELEDERKQRALAAAAKKKLEGDLKDLELQ-ADSAIKGREEAIKQLRKLQAQMKDFQ 1665
Query: 143 KEREE-RIAEAEIENLTGARHMESEKLAQILAARQLEIKQ 181
+E E+ R + EI A E+EK A+ L A +++++
Sbjct: 1666 RELEDARASRDEI----FATAKENEKKAKSLEADLMQLQE 1701
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 45.4 bits (106), Expect = 7e-05
Identities = 30/117 (25%), Positives = 62/117 (52%), Gaps = 6/117 (5%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQL 100
+ E ++ ++ KEL++K+ M+ AV K L +A+LE+++EQ+ RE+
Sbjct: 1789 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 1848
Query: 101 K-LTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIEN 156
K L K+ K+ + + + E++ + +++ EK A K+ + ++ EAE E+
Sbjct: 1849 KSLKQKDKKLKEILLQV-----EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES 1900
Score = 45.1 bits (105), Expect = 9e-05
Identities = 47/182 (25%), Positives = 84/182 (46%), Gaps = 36/182 (19%)
Query: 51 KEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKID 110
++++E+QAK ++ K R+Q E+ K E+EQKH + E+ L ++
Sbjct: 856 RQEEEMQAKEDELQKT------KERQQKAENELK---ELEQKHSQLTEEKNLLQEQ---- 902
Query: 111 SVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQ 170
L+ + ++A++ R + AA ++E EE + E E AR E E Q
Sbjct: 903 ----------LQAETELYAEAEEMRVRLAAKKQELEEILHEME------ARLEEEEDRGQ 946
Query: 171 ILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTN 230
L A + ++ Q D +E+QL+E++ A + L TAE +ED + + +
Sbjct: 947 QLQAERKKMAQQMLD-------LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDD 999
Query: 231 PN 232
N
Sbjct: 1000 QN 1001
Score = 42.7 bits (99), Expect = 4e-04
Identities = 48/162 (29%), Positives = 82/162 (50%), Gaps = 26/162 (16%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAV----PKNDK--KRRKQLTEDVAKLEKE 88
L E+L+EEE ++ + EK +AKI+ +++ + +N+K K RK L E ++ L
Sbjct: 962 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1021
Query: 89 MEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKERE-- 146
+ + EE + LT +NK +S+ IS L + R+ K +K R++ L+++ E
Sbjct: 1022 LAE---EEEKAKNLTKLKNKHESM---ISELEV-----RLKKEEKSRQELEKLKRKLEGD 1070
Query: 147 -----ERIA--EAEIENLTGARHMESEKLAQILAARQLEIKQ 181
E+IA +A+I L + E+L LA EI Q
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ 1112
Score = 36.2 bits (82), Expect = 0.040
Identities = 35/169 (20%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAV------PKNDKKRRKQLTEDVAKLEKE 88
L E+LD E + K+K++L +++ +K + ++ R + ++V L+K
Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA 1189
Query: 89 MEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREER 148
++++ R Q++ +++ A + L + + + +KA + K+ LEKE +
Sbjct: 1190 LDEETRSHEAQVQEMRQKH-----AQAVEELTEQLEQFKRAKANLDKNKQ-TLEKENADL 1243
Query: 149 IAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQL 197
E + G E E + L A+ E++ SDG + D++
Sbjct: 1244 AGELRV---LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1289
Score = 35.8 bits (81), Expect = 0.053
Identities = 47/212 (22%), Positives = 97/212 (45%), Gaps = 35/212 (16%)
Query: 31 MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVA------K 84
MEA L EE D +QL + E+K++ ++ ++ + + + R+K E V K
Sbjct: 934 MEARLEEEEDRGQQL----QAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 989
Query: 85 LEKEM---------EQKHREELEQ--LKLTTKENKIDSVAVNISNLVLENQPPRISKAQK 133
LE E+ K R+ LE+ LTT + + A N++ L +++ IS+ +
Sbjct: 990 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE-SMISELEV 1048
Query: 134 R--REKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYK 191
R +E+K+ E E+ +R E + + H + L +A ++++ + +
Sbjct: 1049 RLKKEEKSRQELEKLKRKLEGDASDF----HEQIADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 192 AIEDQLKEKDCALTVVALRSQTAEYMQSHVED 223
++D++ +K+ AL + ++ H+ D
Sbjct: 1105 RLDDEIAQKNNALKKI-------RELEGHISD 1129
Score = 32.7 bits (73), Expect = 0.45
Identities = 40/194 (20%), Positives = 85/194 (43%), Gaps = 35/194 (18%)
Query: 40 DEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQ 99
D+ E+ R ++E +L + + V +KK+RK + + EK + K+ +E ++
Sbjct: 1423 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK--FDQLLAEEKNISSKYADERDR 1480
Query: 100 LKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENL-- 157
+ +E + ++++ + +A + +E E ER ++ +AE+E+L
Sbjct: 1481 AEAEAREKETKALSL----------ARALEEALEAKE-----ELERTNKMLKAEMEDLVS 1525
Query: 158 ----TGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCA-----LTVVA 208
G E EK + L + E+K + +ED+L+ + A + + A
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMK-------TQLEELEDELQATEDAKLRLEVNMQA 1578
Query: 209 LRSQTAEYMQSHVE 222
L+ Q +Q+ E
Sbjct: 1579 LKGQFERDLQARDE 1592
Score = 32.7 bits (73), Expect = 0.45
Identities = 36/168 (21%), Positives = 80/168 (47%), Gaps = 16/168 (9%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHR 94
L E L+ +E+L R ++ K E++ + K+ V KN +L + LE +ME+ +
Sbjct: 1499 LEEALEAKEELERTNKMLKAEMEDLVSS-KDDVGKNVH----ELEKSKRALETQMEEM-K 1552
Query: 95 EELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEI 154
+LE+L+ + + + + ++ L+ Q R +A+ + ++ + +R+ E E+
Sbjct: 1553 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1612
Query: 155 ENLTGARHMESEKLAQILAARQL---EIKQIPSDGHCMYKAIEDQLKE 199
E+ E ++ A AA++ ++K + K E+ +K+
Sbjct: 1613 ED-------ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1653
Score = 30.0 bits (66), Expect = 2.9
Identities = 34/160 (21%), Positives = 76/160 (47%), Gaps = 15/160 (9%)
Query: 31 MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKN-------AVPKNDKKRRKQLTEDVA 83
ME + T+ L+E E L+ K L+ +Q +K A + ++++R+QL +
Sbjct: 1548 MEEMKTQ-LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1606
Query: 84 KLEKEMEQKHREELEQLKLTTK-ENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALE 142
+ E E+E + ++ K E + + + ++ ++ + I + +K + + +
Sbjct: 1607 EYETELEDERKQRALAAAAKKKLEGDLKDLELQ-ADSAIKGREEAIKQLRKLQAQMKDFQ 1665
Query: 143 KEREE-RIAEAEIENLTGARHMESEKLAQILAARQLEIKQ 181
+E E+ R + EI A E+EK A+ L A +++++
Sbjct: 1666 RELEDARASRDEI----FATAKENEKKAKSLEADLMQLQE 1701
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 45.4 bits (106), Expect = 7e-05
Identities = 30/117 (25%), Positives = 62/117 (52%), Gaps = 6/117 (5%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQL 100
+ E ++ ++ KEL++K+ M+ AV K L +A+LE+++EQ+ RE+
Sbjct: 1782 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 1841
Query: 101 K-LTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIEN 156
K L K+ K+ + + + E++ + +++ EK A K+ + ++ EAE E+
Sbjct: 1842 KSLKQKDKKLKEILLQV-----EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES 1893
Score = 45.1 bits (105), Expect = 9e-05
Identities = 47/182 (25%), Positives = 84/182 (46%), Gaps = 36/182 (19%)
Query: 51 KEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKID 110
++++E+QAK ++ K R+Q E+ K E+EQKH + E+ L ++
Sbjct: 849 RQEEEMQAKEDELQKT------KERQQKAENELK---ELEQKHSQLTEEKNLLQEQ---- 895
Query: 111 SVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQ 170
L+ + ++A++ R + AA ++E EE + E E AR E E Q
Sbjct: 896 ----------LQAETELYAEAEEMRVRLAAKKQELEEILHEME------ARLEEEEDRGQ 939
Query: 171 ILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTN 230
L A + ++ Q D +E+QL+E++ A + L TAE +ED + + +
Sbjct: 940 QLQAERKKMAQQMLD-------LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDD 992
Query: 231 PN 232
N
Sbjct: 993 QN 994
Score = 42.7 bits (99), Expect = 4e-04
Identities = 48/162 (29%), Positives = 82/162 (50%), Gaps = 26/162 (16%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAV----PKNDK--KRRKQLTEDVAKLEKE 88
L E+L+EEE ++ + EK +AKI+ +++ + +N+K K RK L E ++ L
Sbjct: 955 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
Query: 89 MEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKERE-- 146
+ + EE + LT +NK +S+ IS L + R+ K +K R++ L+++ E
Sbjct: 1015 LAE---EEEKAKNLTKLKNKHESM---ISELEV-----RLKKEEKSRQELEKLKRKLEGD 1063
Query: 147 -----ERIA--EAEIENLTGARHMESEKLAQILAARQLEIKQ 181
E+IA +A+I L + E+L LA EI Q
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ 1105
Score = 36.2 bits (82), Expect = 0.040
Identities = 35/169 (20%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAV------PKNDKKRRKQLTEDVAKLEKE 88
L E+LD E + K+K++L +++ +K + ++ R + ++V L+K
Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA 1182
Query: 89 MEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREER 148
++++ R Q++ +++ A + L + + + +KA + K+ LEKE +
Sbjct: 1183 LDEETRSHEAQVQEMRQKH-----AQAVEELTEQLEQFKRAKANLDKNKQ-TLEKENADL 1236
Query: 149 IAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQL 197
E + G E E + L A+ E++ SDG + D++
Sbjct: 1237 AGELRV---LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Score = 35.8 bits (81), Expect = 0.053
Identities = 47/212 (22%), Positives = 97/212 (45%), Gaps = 35/212 (16%)
Query: 31 MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVA------K 84
MEA L EE D +QL + E+K++ ++ ++ + + + R+K E V K
Sbjct: 927 MEARLEEEEDRGQQL----QAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 85 LEKEM---------EQKHREELEQ--LKLTTKENKIDSVAVNISNLVLENQPPRISKAQK 133
LE E+ K R+ LE+ LTT + + A N++ L +++ IS+ +
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE-SMISELEV 1041
Query: 134 R--REKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYK 191
R +E+K+ E E+ +R E + + H + L +A ++++ + +
Sbjct: 1042 RLKKEEKSRQELEKLKRKLEGDASDF----HEQIADLQAQIAELKMQLAKKEEELQAALA 1097
Query: 192 AIEDQLKEKDCALTVVALRSQTAEYMQSHVED 223
++D++ +K+ AL + ++ H+ D
Sbjct: 1098 RLDDEIAQKNNALKKI-------RELEGHISD 1122
Score = 32.7 bits (73), Expect = 0.45
Identities = 40/194 (20%), Positives = 85/194 (43%), Gaps = 35/194 (18%)
Query: 40 DEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQ 99
D+ E+ R ++E +L + + V +KK+RK + + EK + K+ +E ++
Sbjct: 1416 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK--FDQLLAEEKNISSKYADERDR 1473
Query: 100 LKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENL-- 157
+ +E + ++++ + +A + +E E ER ++ +AE+E+L
Sbjct: 1474 AEAEAREKETKALSL----------ARALEEALEAKE-----ELERTNKMLKAEMEDLVS 1518
Query: 158 ----TGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCA-----LTVVA 208
G E EK + L + E+K + +ED+L+ + A + + A
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMK-------TQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 209 LRSQTAEYMQSHVE 222
L+ Q +Q+ E
Sbjct: 1572 LKGQFERDLQARDE 1585
Score = 32.7 bits (73), Expect = 0.45
Identities = 36/168 (21%), Positives = 80/168 (47%), Gaps = 16/168 (9%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHR 94
L E L+ +E+L R ++ K E++ + K+ V KN +L + LE +ME+ +
Sbjct: 1492 LEEALEAKEELERTNKMLKAEMEDLVSS-KDDVGKNVH----ELEKSKRALETQMEEM-K 1545
Query: 95 EELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEI 154
+LE+L+ + + + + ++ L+ Q R +A+ + ++ + +R+ E E+
Sbjct: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605
Query: 155 ENLTGARHMESEKLAQILAARQL---EIKQIPSDGHCMYKAIEDQLKE 199
E+ E ++ A AA++ ++K + K E+ +K+
Sbjct: 1606 ED-------ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646
Score = 30.0 bits (66), Expect = 2.9
Identities = 34/160 (21%), Positives = 76/160 (47%), Gaps = 15/160 (9%)
Query: 31 MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKN-------AVPKNDKKRRKQLTEDVA 83
ME + T+ L+E E L+ K L+ +Q +K A + ++++R+QL +
Sbjct: 1541 MEEMKTQ-LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLH 1599
Query: 84 KLEKEMEQKHREELEQLKLTTK-ENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALE 142
+ E E+E + ++ K E + + + ++ ++ + I + +K + + +
Sbjct: 1600 EYETELEDERKQRALAAAAKKKLEGDLKDLELQ-ADSAIKGREEAIKQLRKLQAQMKDFQ 1658
Query: 143 KEREE-RIAEAEIENLTGARHMESEKLAQILAARQLEIKQ 181
+E E+ R + EI A E+EK A+ L A +++++
Sbjct: 1659 RELEDARASRDEI----FATAKENEKKAKSLEADLMQLQE 1694
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 45.1 bits (105), Expect = 9e-05
Identities = 31/128 (24%), Positives = 60/128 (46%), Gaps = 6/128 (4%)
Query: 31 MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEME 90
++ L E L E E++ H EK +L +++ KN + + ++ + + E ++ + +E
Sbjct: 319 LQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 378
Query: 91 QKHREELEQLK-----LTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKER 145
K EE+ QL+ +TT+ ++ E +S AQK E + L+ E
Sbjct: 379 MKE-EEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEM 437
Query: 146 EERIAEAE 153
+E+I E
Sbjct: 438 DEQIKTIE 445
Score = 43.1 bits (100), Expect = 3e-04
Identities = 49/213 (23%), Positives = 86/213 (40%), Gaps = 22/213 (10%)
Query: 29 VVMEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQL-------TED 81
V E V + EEQ+ + + +KEL K Q + + +++ ++Q+ +
Sbjct: 462 VKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSE 521
Query: 82 VAKLEKEMEQKHREELEQLK------LTTKENKI-----DSVAVNISNLVLENQPPRISK 130
K+ +E EQ+ LE+L+ LT ENK+ ++ L LE+ + +
Sbjct: 522 YLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQ 581
Query: 131 AQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMY 190
K + K A+ E E+ EI + E E L A E Q+ Y
Sbjct: 582 ENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQ---QY 638
Query: 191 KAIEDQLKEKDCALTVVALRSQTAEYMQSHVED 223
+ ++L+EK C L Q+H+E+
Sbjct: 639 QTEMEKLREK-CEQEKETLLKDKEIIFQAHIEE 670
Score = 38.9 bits (89), Expect = 0.006
Identities = 37/202 (18%), Positives = 91/202 (45%), Gaps = 22/202 (10%)
Query: 32 EAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNA----VPKNDKKRRKQLTEDVAKLEK 87
E + T E EE+ + ++ + Q + MK + + K K K+L +L K
Sbjct: 439 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTK 498
Query: 88 EMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREE 147
+++ + RE EQ+K+ ++++ + + +IS+ ++++E A E E ++
Sbjct: 499 KLQTREREFQEQMKVALEKSQSEYL--------------KISQEKEQQESLALEELELQK 544
Query: 148 RIAEAEIENLTGARHMESE----KLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCA 203
+ E EN E+E ++ ++ ++ + +++ + + +E + + +
Sbjct: 545 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKE 604
Query: 204 LTVVALRSQTAEYMQSHVEDFL 225
+TV+ + +T H +D L
Sbjct: 605 ITVMVEKHKTELESLKHQQDAL 626
Score = 33.9 bits (76), Expect = 0.20
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 17/141 (12%)
Query: 34 VLTEELDEEEQ----LLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEM 89
+LT++L +E L + + K + K++ +K + + +K+L + AKL+KE+
Sbjct: 926 ILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKEL 985
Query: 90 EQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERI 149
E L+L+ KE + ++ + ++ + IS A R E +KE+ E +
Sbjct: 986 EN------TALELSQKEKQFNAKMLEMA----QANSAGISDAVSRLETN---QKEQIESL 1032
Query: 150 AEAEIENLTGARHMESEKLAQ 170
E L + +KL Q
Sbjct: 1033 TEVHRRELNDVISIWEKKLNQ 1053
Score = 33.9 bits (76), Expect = 0.20
Identities = 44/178 (24%), Positives = 73/178 (41%), Gaps = 28/178 (15%)
Query: 31 MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEME 90
+E V +EE+L + + E AK+ +K + +KQL + EKE +
Sbjct: 1608 LEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQME--EKEEQ 1665
Query: 91 QKHREELEQLKLTTK-----------ENKIDSVAVNISNLVLENQPPRISK------AQK 133
K E +L TK E K+ SV + S ++ PR +K Q+
Sbjct: 1666 YKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLI---VPRSAKNVAAYTEQE 1722
Query: 134 RREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYK 191
+ + ++K EE+I+ + NLT E EKL Q + + E + C Y+
Sbjct: 1723 EADSQGCVQKTYEEKISVLQ-RNLT-----EKEKLLQRVGQEKEETVSSHFEMRCQYQ 1774
Score = 29.6 bits (65), Expect = 3.8
Identities = 39/170 (22%), Positives = 79/170 (46%), Gaps = 18/170 (10%)
Query: 51 KEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKID 110
+EK++L +I ++ + K+ +++L + ++E E+K ++E E L+L K N
Sbjct: 1937 REKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLEL--KHNSTL 1994
Query: 111 SVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQ 170
+ N L AQK +E + + KE + E E E L + E+ +L +
Sbjct: 1995 KQLMREFNTQL---------AQKEQELEMTI-KETINKAQEVEAE-LLESHQEETNQLLK 2043
Query: 171 ILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSH 220
+A + ++K+ Y+ I D +E++ V L++Q E + +
Sbjct: 2044 KIAEKDDDLKRTAK----RYEEILD-AREEEMTAKVRDLQTQLEELQKKY 2088
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 45.1 bits (105), Expect = 9e-05
Identities = 39/165 (23%), Positives = 80/165 (48%), Gaps = 12/165 (7%)
Query: 42 EEQLLRRHRKEKKELQAKIQGMKNAVPKNDKK---RRKQLTEDVAKLEKEMEQKHREELE 98
+E L + R++++E +A+I+ +KN+ ++ K+ +L + ++ RE+
Sbjct: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRRED-- 71
Query: 99 QLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKERE---ERIAEAEIE 155
+ + + DS+A+ + + K +KR+EKK A KE+E ER E
Sbjct: 72 --SMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREE 129
Query: 156 NLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEK 200
R E +K ++ AR+ ++ +DG C+++ +QL+ K
Sbjct: 130 QDKARREWERQKRREM--AREHSRRERGNDGVCLFRDRLEQLERK 172
Score = 38.5 bits (88), Expect = 0.008
Identities = 35/130 (26%), Positives = 67/130 (51%), Gaps = 9/130 (6%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREE 96
+++ +E++ HRK++K + K +K + + +RRK+ E+ K +E E++ R E
Sbjct: 89 QQMSRKEKV--HHRKDEKRKEKKHARVKEK--EREHERRKRHREEQDKARREWERQKRRE 144
Query: 97 LEQLKLTTKENKIDSVAVNISNLV-LENQPPRISKA-QKRREKKAALEKER--EERIAEA 152
+ + + + +E D V + L LE + R K ++++E++ E+ER EER E
Sbjct: 145 MAR-EHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKER 203
Query: 153 EIENLTGARH 162
E A H
Sbjct: 204 EARREVSAHH 213
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 45.1 bits (105), Expect = 9e-05
Identities = 39/162 (24%), Positives = 75/162 (46%), Gaps = 15/162 (9%)
Query: 36 TEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHRE 95
TE + + + L+ + K LQ KI ++ + ++ QL E + KLE+ E+K E
Sbjct: 730 TETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERK--E 787
Query: 96 ELEQLKLTTKENKIDSVAVNISNL------------VLENQPPRISKAQKRREKKAALEK 143
+L+Q +L KE +++ + S L LE Q + + + +EKK E+
Sbjct: 788 KLKQ-QLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAER 846
Query: 144 EREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSD 185
++ + + +E L ++ I+ A Q EI Q+ ++
Sbjct: 847 DKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANE 888
Score = 33.1 bits (74), Expect = 0.34
Identities = 51/213 (23%), Positives = 95/213 (44%), Gaps = 25/213 (11%)
Query: 25 LGYLVVMEAVLT--EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDV 82
L +L +E L E ++Q + ++ EL+A + + + R ++ + +
Sbjct: 425 LKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHREREQAQQL 484
Query: 83 AKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRRE--KKAA 140
+L EQ+HR+ELE + T + D++A I+ +++ I + Q++ + +
Sbjct: 485 HQLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHE-QMIKEYQEKIDVLSQQY 543
Query: 141 LEKEREERIA---EAE--------IENLTGARHMESEKLAQILAAR-QLEIKQIPSDGHC 188
++ E E RIA EA EN+ A + K A I A R + E + D C
Sbjct: 544 MDLENEFRIALTVEARRFQDVKDGFENV--ATELAKSKHALIWAQRKENESSSLIKDLTC 601
Query: 189 MYKAIEDQLKEKDCALTVVALRSQTAEYMQSHV 221
M K + +L E V L+ +TA +Q+ +
Sbjct: 602 MVKEQKTKLAE------VSKLKQETAANLQNQI 628
Score = 31.6 bits (70), Expect = 1.00
Identities = 36/181 (19%), Positives = 77/181 (42%), Gaps = 21/181 (11%)
Query: 37 EELDEEEQLLR-RHRKEKKELQAKI--------QGMKNAVPKNDKKRRKQLTEDVAKLEK 87
E+ + QLL + ++ +KEL+ + + + K +KK + + E K++
Sbjct: 479 EQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDV 538
Query: 88 EMEQKHREELE-QLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKERE 146
+Q E E ++ LT + + V N+ E + K A + +R+
Sbjct: 539 LSQQYMDLENEFRIALTVEARRFQDVKDGFENVATE----------LAKSKHALIWAQRK 588
Query: 147 ERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTV 206
E + + I++LT + KLA++ +Q + + + + IED K+K + +
Sbjct: 589 ENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDD-KQKSIQIEL 647
Query: 207 V 207
+
Sbjct: 648 L 648
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 45.1 bits (105), Expect = 9e-05
Identities = 39/162 (24%), Positives = 75/162 (46%), Gaps = 15/162 (9%)
Query: 36 TEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHRE 95
TE + + + L+ + K LQ KI ++ + ++ QL E + KLE+ E+K E
Sbjct: 823 TETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERHNERK--E 880
Query: 96 ELEQLKLTTKENKIDSVAVNISNL------------VLENQPPRISKAQKRREKKAALEK 143
+L+Q +L KE +++ + S L LE Q + + + +EKK E+
Sbjct: 881 KLKQ-QLKGKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAER 939
Query: 144 EREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSD 185
++ + + +E L ++ I+ A Q EI Q+ ++
Sbjct: 940 DKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANE 981
Score = 33.1 bits (74), Expect = 0.34
Identities = 51/213 (23%), Positives = 95/213 (44%), Gaps = 25/213 (11%)
Query: 25 LGYLVVMEAVLT--EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDV 82
L +L +E L E ++Q + ++ EL+A + + + R ++ + +
Sbjct: 518 LKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLHREREQAQQL 577
Query: 83 AKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRRE--KKAA 140
+L EQ+HR+ELE + T + D++A I+ +++ I + Q++ + +
Sbjct: 578 HQLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHE-QMIKEYQEKIDVLSQQY 636
Query: 141 LEKEREERIA---EAE--------IENLTGARHMESEKLAQILAAR-QLEIKQIPSDGHC 188
++ E E RIA EA EN+ A + K A I A R + E + D C
Sbjct: 637 MDLENEFRIALTVEARRFQDVKDGFENV--ATELAKSKHALIWAQRKENESSSLIKDLTC 694
Query: 189 MYKAIEDQLKEKDCALTVVALRSQTAEYMQSHV 221
M K + +L E V L+ +TA +Q+ +
Sbjct: 695 MVKEQKTKLAE------VSKLKQETAANLQNQI 721
Score = 31.6 bits (70), Expect = 1.00
Identities = 36/181 (19%), Positives = 77/181 (42%), Gaps = 21/181 (11%)
Query: 37 EELDEEEQLLR-RHRKEKKELQAKI--------QGMKNAVPKNDKKRRKQLTEDVAKLEK 87
E+ + QLL + ++ +KEL+ + + + K +KK + + E K++
Sbjct: 572 EQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEKIDV 631
Query: 88 EMEQKHREELE-QLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKERE 146
+Q E E ++ LT + + V N+ E + K A + +R+
Sbjct: 632 LSQQYMDLENEFRIALTVEARRFQDVKDGFENVATE----------LAKSKHALIWAQRK 681
Query: 147 ERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTV 206
E + + I++LT + KLA++ +Q + + + + IED K+K + +
Sbjct: 682 ENESSSLIKDLTCMVKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDD-KQKSIQIEL 740
Query: 207 V 207
+
Sbjct: 741 L 741
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 44.7 bits (104), Expect = 1e-04
Identities = 33/125 (26%), Positives = 62/125 (49%), Gaps = 9/125 (7%)
Query: 32 EAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQ 91
E ++ D Q L R + KEL+AK+Q ++ AV K L + +LE+++EQ
Sbjct: 1776 ERSAAQKSDNARQQLER---QNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ 1832
Query: 92 KHREELEQLKLTTK-ENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIA 150
+ +E KL + E K+ + + + E++ + +++ EK A K+ + ++
Sbjct: 1833 EAKERAAANKLVRRTEKKLKEIFMQV-----EDERRHADQYKEQMEKANARMKQLKRQLE 1887
Query: 151 EAEIE 155
EAE E
Sbjct: 1888 EAEEE 1892
Score = 41.6 bits (96), Expect = 0.001
Identities = 67/252 (26%), Positives = 110/252 (43%), Gaps = 33/252 (13%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDV---AKLEKEMEQ 91
L ++EEE+ + + EKK++QA IQ ++ + + + R+K E V AK+ K+ME+
Sbjct: 927 LESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKI-KKMEE 985
Query: 92 KHREELEQLKLTTKENKI--DSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERI 149
+ +Q KE K+ D +A S L E + + K R K+ + + EER+
Sbjct: 986 EILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE--KAKNLAKIRNKQEVMISDLEERL 1043
Query: 150 -----AEAEIENLTGARHMESEKLAQILAARQLEIK----QIPSDGHCMYKAI---EDQL 197
E+E E+ L +A Q +I Q+ + A+ +D+
Sbjct: 1044 KKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDET 1103
Query: 198 KEKDCALTVV-ALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTP------EEFQKYCEDIV 250
K+ AL VV L++Q AE EDF + N + E + ED +
Sbjct: 1104 LHKNNALKVVRELQAQIAELQ----EDFESEKASRNKAEKQKRDLSEELEALKTELEDTL 1159
Query: 251 NTAAWGGQLELR 262
+T A Q ELR
Sbjct: 1160 DTTA--AQQELR 1169
Score = 38.9 bits (89), Expect = 0.006
Identities = 60/281 (21%), Positives = 125/281 (44%), Gaps = 30/281 (10%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKND---KKRRKQLTEDVAKLEKEMEQ 91
L E L+ +E+ R++++ + +++ + K+ V KN +K ++ L + V ++ ++E
Sbjct: 1492 LEEALEAKEEFERQNKQLRADME-DLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLE- 1549
Query: 92 KHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAE 151
ELE T++ K+ + VN+ + + + ++ ++ EKK L K+ E AE
Sbjct: 1550 ----ELEDELQATEDAKL-RLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAE 1604
Query: 152 AEIENLTGARHMESEKL---------AQILA---ARQLEIKQIPSDGHCMYKAIEDQLKE 199
E E A + S+K AQI A AR IKQ+ K + +L+E
Sbjct: 1605 LEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQL-RKLQAQMKDYQRELEE 1663
Query: 200 KDCALTVVALRSQTAE----YMQSHVEDFLPFLTNPNTGDMYTPEEFQKYCEDIVNTAAW 255
+ + +S+ +E +++ + L + + +E + ++I N+A+
Sbjct: 1664 ARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASG 1723
Query: 256 GGQL---ELRALSHILQTPIEIIQADSPPIIVGEEYSKKPL 293
L + R + I Q E+ + S ++ + + K L
Sbjct: 1724 KSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTL 1764
Score = 36.2 bits (82), Expect = 0.040
Identities = 45/194 (23%), Positives = 84/194 (43%), Gaps = 49/194 (25%)
Query: 40 DEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQ 99
+EE Q + KE Q K++G +LE EME+KH++ LE+
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEG---------------------ELE-EMERKHQQLLEE 888
Query: 100 LKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTG 159
+ ++ L+ + ++A++ R + AA ++E EE + + E
Sbjct: 889 KNILAEQ--------------LQAETELFAEAEEMRARLAAKKQELEEILHDLE------ 928
Query: 160 ARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQS 219
+R E E+ QIL + +++ D +E+QL E++ A + L TAE
Sbjct: 929 SRVEEEEERNQILQNEKKKMQAHIQD-------LEEQLDEEEGARQKLQLEKVTAEAKIK 981
Query: 220 HVEDFLPFLTNPNT 233
+E+ + L + N+
Sbjct: 982 KMEEEILLLEDQNS 995
Score = 30.4 bits (67), Expect = 2.2
Identities = 50/242 (20%), Positives = 99/242 (40%), Gaps = 66/242 (27%)
Query: 32 EAVLTEELDE----EEQLLRRHRKEKK--------------ELQAKIQGMKNAVPKNDKK 73
+ V+ +L+E EE+ + K K+ ELQA+I +K + K +++
Sbjct: 1032 QEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEE 1091
Query: 74 RR--------------------KQLTEDVAKLEKEMEQKH-------------REELEQL 100
+ ++L +A+L+++ E + EELE L
Sbjct: 1092 LQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEAL 1151
Query: 101 KLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGA 160
K T E+ +D+ A Q R + Q+ E K ALE+E + EA+I+++
Sbjct: 1152 K-TELEDTLDTTAA--------QQELRTKREQEVAELKKALEEETKNH--EAQIQDMRQR 1200
Query: 161 RHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSH 220
E+L++ L + K+ ++ + +E KE C + V+ +E+ +
Sbjct: 1201 HATALEELSEQLE----QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKK 1256
Query: 221 VE 222
++
Sbjct: 1257 LD 1258
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/176 (23%), Positives = 82/176 (46%), Gaps = 2/176 (1%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQL 100
EEEQLL+ ++ Q + + + ++ ++ RK L E+ +E E+K +E +QL
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
Query: 101 KLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGA 160
+ +E ++ + E Q R + +K RE++ + ++ ER E + L
Sbjct: 1400 RCQEREQQLRQDR-DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
Query: 161 RHMESEKLAQILAAR-QLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAE 215
RH + + Q+L R + ++ + D + + + + +E+D LRSQ E
Sbjct: 1459 RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514
Score = 43.9 bits (102), Expect = 2e-04
Identities = 43/159 (27%), Positives = 73/159 (45%), Gaps = 24/159 (15%)
Query: 36 TEELDEEEQL-------LRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQ---LTEDVAKL 85
TEE +EEQL LRR +E+K+ Q + + + + +K+ RK+ L ++ KL
Sbjct: 201 TEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKL 260
Query: 86 EKEMEQKHR---EELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALE 142
++E Q+ R EE EQL+ ++ L E Q + + RRE++ +
Sbjct: 261 QEEEPQRQRELQEEEEQLRKLERQ-----------ELRRERQEEEQQQQRLRREQQLRRK 309
Query: 143 KEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQ 181
+E E R + E R + E+ Q L Q E ++
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Score = 43.1 bits (100), Expect = 3e-04
Identities = 38/149 (25%), Positives = 71/149 (47%), Gaps = 23/149 (15%)
Query: 40 DEEEQL-------LRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQK 92
+EEEQL LRR R+E+++ Q +++ + K +++RR+Q E + E+ +Q+
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 93 HREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEA 152
R E +QL+ +E + Q R + ++RRE++ E+E E R +
Sbjct: 333 ERRE-QQLRREQEERR--------------EQQLRREQEEERREQQLRREQEEERREQQL 377
Query: 153 EIENLTGARHMESEKLAQILAARQLEIKQ 181
E R + + Q+ +QL +Q
Sbjct: 378 RREQQL-RREQQLRREQQLRREQQLRREQ 405
Score = 39.7 bits (91), Expect = 0.004
Identities = 31/141 (21%), Positives = 67/141 (47%), Gaps = 8/141 (5%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQL 100
+E Q R E+++LQ+ P ++ RR++L E K +E +Q+ RE +++
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Query: 101 KLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGA 160
+E + VL + ++ + + +R+++ +E EE++ + E + L
Sbjct: 238 FQEEEEKEWRK-----RETVLRKEEEKLQEEEPQRQREL---QEEEEQLRKLERQELRRE 289
Query: 161 RHMESEKLAQILAARQLEIKQ 181
R E ++ ++ +QL KQ
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQ 310
Score = 39.3 bits (90), Expect = 0.005
Identities = 44/204 (21%), Positives = 86/204 (42%), Gaps = 16/204 (7%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQ---------LTEDVAKLEK 87
E+ + EQ L+R E++ Q ++ + + + RR+Q E+ +LE+
Sbjct: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ 670
Query: 88 EMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREE 147
++++H EE + +L +E + I + + + Q S+A R+ K + +++E
Sbjct: 671 RLKREHEEERREQELAEEEQ--EQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG 728
Query: 148 RIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVV 207
+ E E R E + + A RQ + ++ D ++A E + +
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Query: 208 ALRSQ-----TAEYMQSHVEDFLP 226
LR Q AE Q + FLP
Sbjct: 789 PLREQRERQLRAEERQQREQRFLP 812
Score = 38.9 bits (89), Expect = 0.006
Identities = 33/155 (21%), Positives = 70/155 (45%), Gaps = 10/155 (6%)
Query: 37 EELDEEEQLLRRHRKEKKELQA---------KIQGMKNAVPKNDK-KRRKQLTEDVAKLE 86
EEL +EE+ L R +EK+ Q ++Q + + + ++ KRR Q E + E
Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 87 KEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKERE 146
+E++Q+ + L + + T + +++ L E + + +KRR ++ + E
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE 1113
Query: 147 ERIAEAEIENLTGARHMESEKLAQILAARQLEIKQ 181
E + + E + L R + + + E++Q
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
Score = 38.5 bits (88), Expect = 0.008
Identities = 37/148 (25%), Positives = 66/148 (44%), Gaps = 7/148 (4%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEM-EQKHRE 95
E+ + + L R E+ E + + Q +K + ++R +L E+ + ++E EQ+ R
Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Query: 96 ELEQ-----LKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIA 150
E E+ LK +E ++ + L E Q R + KR E+K ++ RE+R+
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRRE-QEERREQLLKREEEKRLEQERREQRLK 568
Query: 151 EAEIENLTGARHMESEKLAQILAARQLE 178
+ E E E+ Q L Q E
Sbjct: 569 REQEERRDQLLKREEERRQQRLKREQEE 596
Score = 38.5 bits (88), Expect = 0.008
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 18/134 (13%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEK-EMEQKHREELEQ 99
EEEQLLR R++++ + + Q K+ K +K + L E+ K + E E+K+REE E
Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDK--KLQQKEEQLLGEEPEKRRRQEREKKYREEEE- 995
Query: 100 LKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTG 159
L +E ++ L E + R + +++ KK L++E E+ + E +
Sbjct: 996 --LQQEEEQL---------LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044
Query: 160 AR---HMESEKLAQ 170
R + E E+L Q
Sbjct: 1045 ERERQYREEEELQQ 1058
Score = 38.1 bits (87), Expect = 0.011
Identities = 35/155 (22%), Positives = 69/155 (44%), Gaps = 17/155 (10%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQL-------------TEDVA 83
E+ + EQLL+R +++ E + + Q +K + ++RR QL E
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLK----REQEERRDQLLKREEERRQQRLKREQEE 596
Query: 84 KLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEK 143
+LE+ ++++ E LEQ + + K + +L+++ + Q+ R ++ +
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
Query: 144 EREERIAEAEIENLTGARHMESEKLAQILAARQLE 178
+R +R E E R E E+ Q LA + E
Sbjct: 657 QRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Score = 38.1 bits (87), Expect = 0.011
Identities = 38/153 (24%), Positives = 69/153 (45%), Gaps = 7/153 (4%)
Query: 39 LDEEEQLLR-RHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHRE-- 95
L+EE+QL + RHRK ++E Q +Q + ++ RK L E+ +E ++K RE
Sbjct: 1449 LEEEQQLRQERHRKFREEEQL-LQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE 1507
Query: 96 ---ELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEA 152
+ + K +E ++ L E Q R + Q+RR+ + +E E+ E
Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567
Query: 153 EIENLTGARHMESEKLAQILAARQLEIKQIPSD 185
E + L+ +L + RQ + ++ D
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMED 1600
Score = 37.4 bits (85), Expect = 0.018
Identities = 36/180 (20%), Positives = 80/180 (44%), Gaps = 19/180 (10%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAV-PKNDKKRRKQLTEDVAKLEKEMEQKHREELEQ 99
EEEQL R +KE K K Q K + + ++KRR+Q T+ + E+++ Q+ E+ +
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 100 LKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRR------------EKKAALEKEREE 147
+ ++ + + + + R+ + ++ R E++ L ++R+
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 148 RIAEAEIENLTGARHMESEKLAQILAARQLEIK------QIPSDGHCMYKAIEDQLKEKD 201
+ E E + R + + Q + ++ E K Q+ + H ++ E L+E++
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Score = 37.0 bits (84), Expect = 0.024
Identities = 31/121 (25%), Positives = 60/121 (49%), Gaps = 10/121 (8%)
Query: 37 EELD-EEEQLLR----RHRKEKKELQAKI-----QGMKNAVPKNDKKRRKQLTEDVAKLE 86
EEL EEEQLLR + R++++E Q + Q + + + +KRR+Q E + E
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143
Query: 87 KEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKERE 146
+E++Q+ + L + + +++ L E + + +KRR+++ +E E
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
Query: 147 E 147
E
Sbjct: 1204 E 1204
Score = 36.6 bits (83), Expect = 0.031
Identities = 40/153 (26%), Positives = 71/153 (46%), Gaps = 12/153 (7%)
Query: 39 LDEEEQLLRRHRKEKK--ELQAKIQGMKNAVPKNDKKRRKQLTE----DVAKLEKEMEQK 92
L EE + RR +EKK E + Q + + + +KRR+Q E +L++E EQ
Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033
Query: 93 HREELEQLKLTTKENKI---DSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERI 149
REE E+ +L +E + + + L+ E + R + +R+ +K ++ EE++
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Query: 150 AEAEIENLTGARHMESEKLAQILAARQLEIKQI 182
E E R E E+ + Q E +Q+
Sbjct: 1094 LREEPEK---RRRQERERQCREEEELQQEEEQL 1123
Score = 36.2 bits (82), Expect = 0.040
Identities = 36/138 (26%), Positives = 68/138 (49%), Gaps = 19/138 (13%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLT---EDVAKLEKEMEQ 91
L E+L +E+QLL ++E++ELQ + + +K+RR++ + +L++E EQ
Sbjct: 895 LQEQLRKEQQLL---QEEEEELQRE---------EREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 92 KHREELEQLKLTTKENKI--DSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERI 149
REE E+ + +E + D +L +P + + ++ REKK E+E ++
Sbjct: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEK--RRRQEREKKYREEEELQQEE 1000
Query: 150 AEAEIENLTGARHMESEK 167
+ E R E E+
Sbjct: 1001 EQLLREEREKRRRQEWER 1018
Score = 34.7 bits (78), Expect = 0.12
Identities = 37/170 (21%), Positives = 71/170 (41%), Gaps = 22/170 (12%)
Query: 37 EELDEEEQLLR-----RHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQ 91
+E D E++ R RH E+++L+ + Q K K+R ++ E+ L +E E+
Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQ-------KEAKRRDRKSQEEKQLLREEREE 1327
Query: 92 KHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAE 151
K R + K +E + E QP R + ++ ++ +E+ + E
Sbjct: 1328 KRRRQETDRKFREEEQLLQE---------REEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
Query: 152 AEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKD 201
E R + K Q L ++ E +Q+ D ++ E QL ++
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQERE-QQLRQDRDRKFREEEQQLSRQE 1427
Score = 34.7 bits (78), Expect = 0.12
Identities = 30/124 (24%), Positives = 56/124 (45%), Gaps = 10/124 (8%)
Query: 40 DEEEQLLRRHRKEKKELQAKIQGMKNAVPKN-----DKKRRK-----QLTEDVAKLEKEM 89
+ EEQ L R +++K L+ + Q + + D+K R+ Q E+ +E
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQER 1689
Query: 90 EQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERI 149
++K REE +QL+ +E K + LE + + ++ E++ +ER +I
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI 1749
Query: 150 AEAE 153
E E
Sbjct: 1750 LEEE 1753
Score = 34.3 bits (77), Expect = 0.15
Identities = 37/161 (22%), Positives = 75/161 (46%), Gaps = 16/161 (9%)
Query: 42 EEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLK 101
EEQ +RR +E+K ++ ++++ R+Q E +L +E ++K RE+ EQL
Sbjct: 1584 EEQKVRRQEQERKFME------------DEQQLRRQ--EGQQQLRQERDRKFRED-EQLL 1628
Query: 102 LTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENL-TGA 160
+E ++ + L E Q R + Q+ R + +E E+ + E E + L
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQE 1688
Query: 161 RHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKD 201
R + + Q L ++ E K + + + +E + +E++
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729
Score = 34.3 bits (77), Expect = 0.15
Identities = 37/180 (20%), Positives = 79/180 (43%), Gaps = 23/180 (12%)
Query: 40 DEEEQLLRRHRKEKK--ELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQ------ 91
+ EEQ LRR +++K E + Q + ++ + RK E+ + E+E +Q
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Query: 92 --KHREELEQLKLTTKENKI-----------DSVAVNISNLVLENQPPRISKAQKRREKK 138
K+R E EQL+L +E ++ + A + E + + + ++R+E++
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE 1877
Query: 139 AALEKE--REERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQ 196
L +E R ++ E + + E + ++L + +P +Y+ I++Q
Sbjct: 1878 RKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQ 1937
Score = 33.9 bits (76), Expect = 0.20
Identities = 33/152 (21%), Positives = 70/152 (46%), Gaps = 15/152 (9%)
Query: 32 EAVLTEELDEE--EQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEM 89
E L E +EE EQ LRR ++E++ Q + + + RR+Q +L +E
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQ--------QLRREQQLRREQQLRREQQLRREQ 399
Query: 90 EQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERI 149
+ + ++L + + +E ++ L E + R + ++ ++ L++E+EER
Sbjct: 400 QLRREQQLRREQQLRREQQLR----REQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Query: 150 AEAEIENLTGARHMESEKLAQILAARQLEIKQ 181
+ E T RH + + Q+ ++ E ++
Sbjct: 456 DWLKREEET-ERHEQERRKQQLKRDQEEERRE 486
Score = 33.5 bits (75), Expect = 0.26
Identities = 33/165 (20%), Positives = 73/165 (44%), Gaps = 9/165 (5%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREE 96
+E E+QL R +E++E Q + + + +++R +QL + +L +E + + ++
Sbjct: 343 QEERREQQLRREQEEERREQQLRRE-------QEEERREQQLRRE-QQLRREQQLRREQQ 394
Query: 97 LEQLKLTTKENKI-DSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIE 155
L + + +E ++ + + Q R + ++R E+K E+ + E E
Sbjct: 395 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEER 454
Query: 156 NLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEK 200
R E+E+ Q +QL+ Q K E++ +E+
Sbjct: 455 RDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ 499
Score = 33.1 bits (74), Expect = 0.34
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 14/130 (10%)
Query: 41 EEEQLLRRHRKEKK--ELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELE 98
+EEQ LRR E+K E + Q + + ++ RK L E+ + E+E +Q R+E +
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 99 QLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLT 158
+ K +E E Q R ++ ++ ++ L +EREE+ + +
Sbjct: 1771 R-KFREEEQLRQE---------REEQQLRSQESDRKFREEEQLRQEREEQ--QLRPQQRD 1818
Query: 159 GARHMESEKL 168
G E E+L
Sbjct: 1819 GKYRWEEEQL 1828
Score = 31.6 bits (70), Expect = 1.00
Identities = 29/139 (20%), Positives = 63/139 (45%), Gaps = 27/139 (19%)
Query: 38 ELDEEEQLLRRHRKEKKELQ--------------AKIQGMKNAVPKNDKKRRKQLTEDVA 83
E +E+EQ R+ R+ +KELQ ++Q ++ + ++ ++RR Q
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQ------ 866
Query: 84 KLEKEMEQKHREELEQLKLTTKENKIDSVA----VNISNLVLENQPPRISKAQKRREKKA 139
E+ +QK R +LE+ + + A + +L+ + + + ++ + ++
Sbjct: 867 --EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 924
Query: 140 ALEKE-REERIAEAEIENL 157
E++ REE + E E L
Sbjct: 925 EQERQYREEEQLQQEEEQL 943
Score = 31.6 bits (70), Expect = 1.00
Identities = 35/142 (24%), Positives = 63/142 (44%), Gaps = 10/142 (7%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREE 96
E EEEQLLR ++++ + + Q + + ++ + L E+ K +E E+++REE
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYREE--EELQQEEEQLLREEQEKRRQERERQYREE 1202
Query: 97 LEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIEN 156
E + K+ D S+L + +P K R+ K + E+ + E
Sbjct: 1203 EELQRQKRKQRYRDE--DQRSDLKWQWEP---EKENAVRDNKVYCKGRENEQFRQLEDSQ 1257
Query: 157 LTGARHMESEKLAQILAARQLE 178
L R +S++ Q L Q E
Sbjct: 1258 L---RDRQSQQDLQHLLGEQQE 1276
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/157 (21%), Positives = 69/157 (43%), Gaps = 16/157 (10%)
Query: 37 EELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKL----------E 86
+ L E+QL R+ +E++E Q + + + + +++R +QL + + E
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 87 KEMEQKHREELEQLK---LTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEK 143
+ EQ+ R E E+ + +E ++ L + + Q RRE++ E+
Sbjct: 358 ERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 417
Query: 144 E--REERIAEAEIENLTGARHMESEKLAQILAARQLE 178
+ RE+++ + E +H E E+ Q L Q E
Sbjct: 418 QLRREQQLRREQEEERHEQKH-EQERREQRLKREQEE 453
Score = 28.5 bits (62), Expect = 8.4
Identities = 18/69 (26%), Positives = 40/69 (57%), Gaps = 11/69 (15%)
Query: 38 ELDEEEQLLRRHR------KEKKELQAKIQGMKNAVPKNDKKRRKQ-----LTEDVAKLE 86
+L+E+EQ LR+ R +E+ Q K + + + + ++++R+Q L E+ + +
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888
Query: 87 KEMEQKHRE 95
++ EQ+HR+
Sbjct: 1889 QKEEQRHRQ 1897
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 44.7 bits (104), Expect = 1e-04
Identities = 46/171 (26%), Positives = 78/171 (45%), Gaps = 28/171 (16%)
Query: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQL 100
E E+LL + EK+ LQ+KI ++ + K + + + E V LE + RE L +
Sbjct: 625 ENEKLLTQMESEKENLQSKINHLETCL-KTQQIKSHEYNERVRTLEMD-----RENLS-V 677
Query: 101 KLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIEN---- 156
++ N +DS +V + L A ++KA ++ ++ EIEN
Sbjct: 678 EIRNLHNVLDSKSVEVETQKL---------AYMELQQKAEFSDQKHQK----EIENMCLK 724
Query: 157 ---LTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCAL 204
LTG KL Q+L+ ++ + D H Y+++ D LK KD +L
Sbjct: 725 TSQLTGQVEDLEHKL-QLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASL 774
Score = 32.7 bits (73), Expect = 0.45
Identities = 30/149 (20%), Positives = 62/149 (41%), Gaps = 12/149 (8%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRR------KQLTEDVAKLEKE 88
L L Q+L +K K + + +K + K + KQL E+ L+KE
Sbjct: 2756 LNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKE 2815
Query: 89 MEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAAL-----EK 143
+ Q + +Q T + K+D + I L E + +A + +K +L +
Sbjct: 2816 LSQLQAAQEKQKTGTVMDTKVDELTTEIKEL-KETLEEKTKEADEYLDKYCSLLISHEKL 2874
Query: 144 EREERIAEAEIENLTGARHMESEKLAQIL 172
E+ + + E ++ +L + + + + +L
Sbjct: 2875 EKAKEMLETQVAHLCSQQSKQDSRGSPLL 2903
Score = 31.2 bits (69), Expect = 1.3
Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 19/155 (12%)
Query: 52 EKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENK--- 108
E+ +L+ ++ M D QL+E + + +E+E E L +++ E K
Sbjct: 1959 ERNQLRGELDTMSKKTTALD-----QLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKT 2013
Query: 109 --IDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREE-RIAEAEIENLTGARHMES 165
+ +++ ++S L+ + +EK +LEK+ + + + E+EN + E
Sbjct: 2014 ELLQTLSSDVSELLKDKT--------HLQEKLQSLEKDSQALSLTKCELENQIAQLNKEK 2065
Query: 166 EKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEK 200
E L + + Q + + + + KA+E L EK
Sbjct: 2066 ELLVKESESLQARLSESDYEKLNVSKALEAALVEK 2100
Score = 30.4 bits (67), Expect = 2.2
Identities = 17/75 (22%), Positives = 41/75 (54%), Gaps = 10/75 (13%)
Query: 35 LTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVP----------KNDKKRRKQLTEDVAK 84
+T + E ++ + ++ ELQ ++ G KN + K+ K + K+LT + ++
Sbjct: 2614 MTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSE 2673
Query: 85 LEKEMEQKHREELEQ 99
L+K ++ H++++E+
Sbjct: 2674 LKKSLDCMHKDQVEK 2688
Score = 29.3 bits (64), Expect = 4.9
Identities = 29/141 (20%), Positives = 64/141 (45%), Gaps = 25/141 (17%)
Query: 31 MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEME 90
M+ + + L E EQL++ + + + + + ++N+V E+E E
Sbjct: 1142 MQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVK-----------------ERESE 1184
Query: 91 QKHREELEQLKLTTKENKIDSVAVNISNL--VLENQPPRISKAQKRREKKAALEKEREER 148
+ Q+ L KE +DS + L +L N+ ++ +++K +E L+ E +
Sbjct: 1185 RNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKE---CLQHELQTI 1241
Query: 149 IAEAEIENLTGARHMESEKLA 169
+ E NL + M+S++++
Sbjct: 1242 RGDLETSNL---QDMQSQEIS 1259
Score = 28.9 bits (63), Expect = 6.5
Identities = 48/181 (26%), Positives = 81/181 (44%), Gaps = 26/181 (14%)
Query: 29 VVMEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMK--NAVPKNDKKRRKQLTEDVAKLE 86
VV E + E E+E L + E + QA+IQ +K N + ++ K + L+E ++ +
Sbjct: 898 VVAETLSALENKEKELQLLNDKVETE--QAEIQELKKSNHLLEDSLKELQLLSETLSLEK 955
Query: 87 KEME---QKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEK 143
KEM ++ E+E+L T+EN + + +++ QK E A
Sbjct: 956 KEMSSIISLNKREIEEL---TQENG------TLKEINASLNQEKMNLIQK-SESFANYID 1005
Query: 144 EREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCA 203
ERE+ I+E + + EKL IL R E D YKA +++ + +C
Sbjct: 1006 EREKSISEL-------SDQYKQEKL--ILLQRCEETGNAYEDLSQKYKAAQEKNSKLECL 1056
Query: 204 L 204
L
Sbjct: 1057 L 1057
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,739,915
Number of Sequences: 37866
Number of extensions: 518126
Number of successful extensions: 6620
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 239
Number of HSP's successfully gapped in prelim test: 717
Number of HSP's that attempted gapping in prelim test: 3472
Number of HSP's gapped (non-prelim): 2769
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.