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Search of human proteins with 157041224
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157041224 SH2 domain containing 5 isoform 2 [Homo sapiens]
(339 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157041224 SH2 domain containing 5 isoform 2 [Homo sapiens] 709 0.0
gi|156938287 SH2 domain containing 5 isoform 1 [Homo sapiens] 709 0.0
gi|66529407 tensin [Homo sapiens] 39 0.009
gi|18250298 src-related kinase lacking C-terminal regulatory tyr... 38 0.015
gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens] 37 0.025
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 36 0.043
gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Hom... 33 0.28
gi|38787970 tensin like C1 domain containing phosphatase isoform... 33 0.28
gi|38787957 tensin like C1 domain containing phosphatase isoform... 33 0.28
gi|38787941 tensin like C1 domain containing phosphatase isoform... 33 0.28
gi|5174647 PTK6 protein tyrosine kinase 6 [Homo sapiens] 33 0.36
gi|14149916 Src-like-adaptor 2 isoform a [Homo sapiens] 33 0.48
gi|5729856 GRB2-related adaptor protein [Homo sapiens] 32 0.62
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a... 31 1.4
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b... 31 1.4
gi|65288071 tensin 3 [Homo sapiens] 31 1.4
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 31 1.4
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 31 1.4
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 31 1.4
gi|54792745 SH2 domain containing 1B [Homo sapiens] 31 1.4
gi|28416424 Src-like-adaptor 2 isoform b [Homo sapiens] 31 1.4
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens] 31 1.8
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens] 31 1.8
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens] 31 1.8
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens] 31 1.8
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens] 31 1.8
gi|239746599 PREDICTED: hypothetical protein XP_002343795 [Homo ... 31 1.8
gi|13376439 ubiquitin domain containing 1 [Homo sapiens] 31 1.8
gi|239758139 PREDICTED: hypothetical protein [Homo sapiens] 30 3.1
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap... 30 3.1
>gi|157041224 SH2 domain containing 5 isoform 2 [Homo sapiens]
Length = 339
Score = 709 bits (1829), Expect = 0.0
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 1 MAHALRRILYSTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQL 60
MAHALRRILYSTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQL
Sbjct: 1 MAHALRRILYSTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQL 60
Query: 61 AYLLQHPEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAE 120
AYLLQHPEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAE
Sbjct: 61 AYLLQHPEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAE 120
Query: 121 GLVGSGKELPESEGRARHARLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAR 180
GLVGSGKELPESEGRARHARLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAR
Sbjct: 121 GLVGSGKELPESEGRARHARLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAR 180
Query: 181 EAFPAAWEAWPRGPGGHSCLVESEGSLTENIWAFAGISRPCALALLRRDVLGAFLLWPEL 240
EAFPAAWEAWPRGPGGHSCLVESEGSLTENIWAFAGISRPCALALLRRDVLGAFLLWPEL
Sbjct: 181 EAFPAAWEAWPRGPGGHSCLVESEGSLTENIWAFAGISRPCALALLRRDVLGAFLLWPEL 240
Query: 241 GASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPLD 300
GASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPLD
Sbjct: 241 GASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPLD 300
Query: 301 MGRLNPTYEEQDCGPPGRPPRTLRPLSHAKSEAELQGLG 339
MGRLNPTYEEQDCGPPGRPPRTLRPLSHAKSEAELQGLG
Sbjct: 301 MGRLNPTYEEQDCGPPGRPPRTLRPLSHAKSEAELQGLG 339
>gi|156938287 SH2 domain containing 5 isoform 1 [Homo sapiens]
Length = 423
Score = 709 bits (1829), Expect = 0.0
Identities = 339/339 (100%), Positives = 339/339 (100%)
Query: 1 MAHALRRILYSTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQL 60
MAHALRRILYSTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQL
Sbjct: 85 MAHALRRILYSTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQL 144
Query: 61 AYLLQHPEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAE 120
AYLLQHPEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAE
Sbjct: 145 AYLLQHPEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAE 204
Query: 121 GLVGSGKELPESEGRARHARLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAR 180
GLVGSGKELPESEGRARHARLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAR
Sbjct: 205 GLVGSGKELPESEGRARHARLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAR 264
Query: 181 EAFPAAWEAWPRGPGGHSCLVESEGSLTENIWAFAGISRPCALALLRRDVLGAFLLWPEL 240
EAFPAAWEAWPRGPGGHSCLVESEGSLTENIWAFAGISRPCALALLRRDVLGAFLLWPEL
Sbjct: 265 EAFPAAWEAWPRGPGGHSCLVESEGSLTENIWAFAGISRPCALALLRRDVLGAFLLWPEL 324
Query: 241 GASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPLD 300
GASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPLD
Sbjct: 325 GASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPLD 384
Query: 301 MGRLNPTYEEQDCGPPGRPPRTLRPLSHAKSEAELQGLG 339
MGRLNPTYEEQDCGPPGRPPRTLRPLSHAKSEAELQGLG
Sbjct: 385 MGRLNPTYEEQDCGPPGRPPRTLRPLSHAKSEAELQGLG 423
>gi|66529407 tensin [Homo sapiens]
Length = 1735
Score = 38.5 bits (88), Expect = 0.009
Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 18/127 (14%)
Query: 208 TENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQC-----------GV 256
T W ISR A+ALL+ GAF++ G + L+++ G
Sbjct: 1459 TSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGD 1518
Query: 257 VPHQVFRNHLGR-----YCLEHLPAE--FPSLEALVENHAVTERSLFCPLDMGRLNPTYE 309
+ H++ R+ L L+ P E F SL ALV H++ +L C L + +PT E
Sbjct: 1519 MTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDE 1578
Query: 310 EQDCGPP 316
+D P
Sbjct: 1579 SKDSSGP 1585
>gi|18250298 src-related kinase lacking C-terminal regulatory
tyrosine and N-terminal myristylation sites [Homo
sapiens]
Length = 488
Score = 37.7 bits (86), Expect = 0.015
Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Query: 203 SEGSLTENIWAFAGISRPCALALLRR--DVLGAFLLWPELGASGQWCLSVRTQCGVVPHQ 260
S +L++ W F+G+SR A LL + GAFL+ P + G + LSVR Q V ++
Sbjct: 111 SPETLSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYR 170
Query: 261 VFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPL 299
V G L+ FP LE L+ + + + PL
Sbjct: 171 VSMAADGSLYLQK-GRLFPGLEELLTYYKANWKLIQNPL 208
>gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens]
Length = 330
Score = 37.0 bits (84), Expect = 0.025
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 212 WAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLGRYCL 271
W G+SR A LL +G F++ + G + +SVR + V +V R++ G Y L
Sbjct: 58 WFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFL 117
Query: 272 EHLPAEFPSLEALVE 286
+FPSL LV+
Sbjct: 118 --WTEKFPSLNKLVD 130
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 36.2 bits (82), Expect = 0.043
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 9/73 (12%)
Query: 270 CLEHLPAEFPSLEALVENHAVT---ERSLFCPLDMGRLNPTYEEQDCGPPGRPPRTLRPL 326
CL+ L E SL+ +E HA+T S + PL+ +P GP G P R
Sbjct: 1431 CLQQLKQEMDSLQRQMEEHALTVHESLSSWTPLEPATASPVPPGGHAGPRGDPQR----- 1485
Query: 327 SHAKSEAELQGLG 339
H++S A +G G
Sbjct: 1486 -HSQSRASKEGPG 1497
>gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Homo
sapiens]
Length = 217
Score = 33.5 bits (75), Expect = 0.28
Identities = 31/86 (36%), Positives = 40/86 (46%), Gaps = 7/86 (8%)
Query: 212 WAFAGISRPCALALL---RRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLGR 268
W F I R A +L R D GAFL+ A G + LSV+ V +V R+ G+
Sbjct: 60 WFFGKIPRAKAEEMLSKQRHD--GAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGK 117
Query: 269 YCLEHLPAEFPSLEALVENHAVTERS 294
Y L +F SL LV+ H T S
Sbjct: 118 YFL--WVVKFNSLNELVDYHRSTSVS 141
>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
[Homo sapiens]
Length = 1285
Score = 33.5 bits (75), Expect = 0.28
Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 16/125 (12%)
Query: 208 TENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLG 267
T W +SR A+ALL+ GAFL+ G + L+++ Q ++
Sbjct: 1012 TSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPV 1071
Query: 268 RYCLEHL--------------PAE--FPSLEALVENHAVTERSLFCPLDMGRLNPTYEEQ 311
+ H P+E F SL ALV H+++ SL C L + +P E
Sbjct: 1072 EQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETP 1131
Query: 312 DCGPP 316
+ P
Sbjct: 1132 EAPVP 1136
>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
[Homo sapiens]
Length = 1409
Score = 33.5 bits (75), Expect = 0.28
Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 16/125 (12%)
Query: 208 TENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLG 267
T W +SR A+ALL+ GAFL+ G + L+++ Q ++
Sbjct: 1136 TSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPV 1195
Query: 268 RYCLEHL--------------PAE--FPSLEALVENHAVTERSLFCPLDMGRLNPTYEEQ 311
+ H P+E F SL ALV H+++ SL C L + +P E
Sbjct: 1196 EQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETP 1255
Query: 312 DCGPP 316
+ P
Sbjct: 1256 EAPVP 1260
>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
[Homo sapiens]
Length = 1419
Score = 33.5 bits (75), Expect = 0.28
Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 16/125 (12%)
Query: 208 TENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLG 267
T W +SR A+ALL+ GAFL+ G + L+++ Q ++
Sbjct: 1146 TSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPV 1205
Query: 268 RYCLEHL--------------PAE--FPSLEALVENHAVTERSLFCPLDMGRLNPTYEEQ 311
+ H P+E F SL ALV H+++ SL C L + +P E
Sbjct: 1206 EQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETP 1265
Query: 312 DCGPP 316
+ P
Sbjct: 1266 EAPVP 1270
>gi|5174647 PTK6 protein tyrosine kinase 6 [Homo sapiens]
Length = 451
Score = 33.1 bits (74), Expect = 0.36
Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Query: 197 HSCLVESEGSLTENIWAFAGISRPCALALLRRD--VLGAFLLWPELGASGQWCLSVRTQC 254
H+ L E E ++ W F ISR A+ L+ + GAFL+ S + LSVR
Sbjct: 64 HNYLAERE-TVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQ 122
Query: 255 GVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENH 288
V ++++R GR L F SL LV H
Sbjct: 123 AVRHYKIWRRAGGRLHLNE-AVSFLSLPELVNYH 155
>gi|14149916 Src-like-adaptor 2 isoform a [Homo sapiens]
Length = 261
Score = 32.7 bits (73), Expect = 0.48
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 10/96 (10%)
Query: 212 WAFAGISRPCA--LALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLGRY 269
W + G+SR A L LL + GAFL+ G + LSVR ++ H +
Sbjct: 94 WLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRI--RHYRIH 151
Query: 270 CLEH------LPAEFPSLEALVENHAVTERSLFCPL 299
CL++ FPSL+ALV++++ + C L
Sbjct: 152 CLDNGWLYISPRLTFPSLQALVDHYSELADDICCLL 187
>gi|5729856 GRB2-related adaptor protein [Homo sapiens]
Length = 217
Score = 32.3 bits (72), Expect = 0.62
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 212 WAFAGISRPCALALL-RRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLGRYC 270
W ISR A +L +R+ LGAFL+ + G++ +SV V +V R G+Y
Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119
Query: 271 LEHLPAEFPSLEALVENHAVT 291
L +F SL LV+ + T
Sbjct: 120 L--WEEKFNSLNELVDFYRTT 138
>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
[Homo sapiens]
Length = 1130
Score = 31.2 bits (69), Expect = 1.4
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 206 SLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNH 265
SL ++ W +SR A LL + G+FL+ + GQ +S+R + V +++
Sbjct: 121 SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 180
Query: 266 LGRYCLEHLPAEFPSLEALVENHAVTERSLFCPL 299
G+ + + F +L LV +H+ L L
Sbjct: 181 DGKLYVSS-ESRFNTLAELVHHHSTVADGLITTL 213
>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
[Homo sapiens]
Length = 1149
Score = 31.2 bits (69), Expect = 1.4
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 206 SLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNH 265
SL ++ W +SR A LL + G+FL+ + GQ +S+R + V +++
Sbjct: 140 SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTAS 199
Query: 266 LGRYCLEHLPAEFPSLEALVENHAVTERSLFCPL 299
G+ + + F +L LV +H+ L L
Sbjct: 200 DGKLYVSS-ESRFNTLAELVHHHSTVADGLITTL 232
>gi|65288071 tensin 3 [Homo sapiens]
Length = 1445
Score = 31.2 bits (69), Expect = 1.4
Identities = 37/146 (25%), Positives = 58/146 (39%), Gaps = 24/146 (16%)
Query: 191 PRGPGGHSCLVESEGSLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSV 250
P PG +V+ T W A ISR A+A+L+ G+F++ G + L++
Sbjct: 1152 PDSPGDKLVIVKFVQD-TSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAM 1210
Query: 251 RTQCGVVPHQVFR---------NHLGRYCLEHLPAE------------FPSLEALVENHA 289
+ P V + N L R+ L + F SL ALV H+
Sbjct: 1211 KV--ATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHS 1268
Query: 290 VTERSLFCPLDMGRLNPTYEEQDCGP 315
+T +L C L + +P E + P
Sbjct: 1269 ITPLALPCKLLIPERDPLEEIAESSP 1294
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 31.2 bits (69), Expect = 1.4
Identities = 13/33 (39%), Positives = 17/33 (51%)
Query: 66 HPEERAQPEPCPGPTGEVPLKPLSSSGGLVREP 98
HP+ P P P P+ PL+PL+ S G P
Sbjct: 253 HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 285
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 31.2 bits (69), Expect = 1.4
Identities = 13/33 (39%), Positives = 17/33 (51%)
Query: 66 HPEERAQPEPCPGPTGEVPLKPLSSSGGLVREP 98
HP+ P P P P+ PL+PL+ S G P
Sbjct: 807 HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 839
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 31.2 bits (69), Expect = 1.4
Identities = 13/33 (39%), Positives = 17/33 (51%)
Query: 66 HPEERAQPEPCPGPTGEVPLKPLSSSGGLVREP 98
HP+ P P P P+ PL+PL+ S G P
Sbjct: 807 HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP 839
>gi|54792745 SH2 domain containing 1B [Homo sapiens]
Length = 132
Score = 31.2 bits (69), Expect = 1.4
Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
Query: 221 CALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAE--- 277
C LL+ V G FLL G CL V + V +++FR G Y ++
Sbjct: 15 CETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREKHGYYRIQTAEGSPKQ 74
Query: 278 -FPSLEALV 285
FPSL+ L+
Sbjct: 75 VFPSLKELI 83
>gi|28416424 Src-like-adaptor 2 isoform b [Homo sapiens]
Length = 210
Score = 31.2 bits (69), Expect = 1.4
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 10/86 (11%)
Query: 212 WAFAGISRPCA--LALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLGRY 269
W + G+SR A L LL + GAFL+ G + LSVR ++ H +
Sbjct: 94 WLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRI--RHYRIH 151
Query: 270 CLEH------LPAEFPSLEALVENHA 289
CL++ FPSL+ALV++++
Sbjct: 152 CLDNGWLYISPRLTFPSLQALVDHYS 177
>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
Length = 1167
Score = 30.8 bits (68), Expect = 1.8
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 206 SLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNH 265
SL ++ W +SR A LL + G+FL+ + GQ +S+R + V +++
Sbjct: 152 SLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTA 211
Query: 266 LGRYCLEHLPAEFPSLEALVENHAVTERSLFCPL 299
G+ + + F +L LV +H+ L L
Sbjct: 212 DGKVYVT-AESRFSTLAELVHHHSTVADGLVTTL 244
>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
Length = 1182
Score = 30.8 bits (68), Expect = 1.8
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 206 SLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNH 265
SL ++ W +SR A LL + G+FL+ + GQ +S+R + V +++
Sbjct: 167 SLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTA 226
Query: 266 LGRYCLEHLPAEFPSLEALVENHAVTERSLFCPL 299
G+ + + F +L LV +H+ L L
Sbjct: 227 DGKVYVT-AESRFSTLAELVHHHSTVADGLVTTL 259
>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
Length = 542
Score = 30.8 bits (68), Expect = 1.8
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 206 SLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNH 265
SL ++ W +SR A LL + G+FL+ + GQ +S+R + V +++
Sbjct: 146 SLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTA 205
Query: 266 LGRYCLEHLPAEFPSLEALVENHAVTERSLFCPL 299
G+ + + F +L LV +H+ L L
Sbjct: 206 DGKVYVT-AESRFSTLAELVHHHSTVADGLVTTL 238
>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
Length = 1064
Score = 30.8 bits (68), Expect = 1.8
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 206 SLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNH 265
SL ++ W +SR A LL + G+FL+ + GQ +S+R + V +++
Sbjct: 152 SLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTA 211
Query: 266 LGRYCLEHLPAEFPSLEALVENHAVTERSLFCPL 299
G+ + + F +L LV +H+ L L
Sbjct: 212 DGKVYVT-AESRFSTLAELVHHHSTVADGLVTTL 244
>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
Length = 1146
Score = 30.8 bits (68), Expect = 1.8
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 206 SLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNH 265
SL ++ W +SR A LL + G+FL+ + GQ +S+R + V +++
Sbjct: 131 SLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTA 190
Query: 266 LGRYCLEHLPAEFPSLEALVENHAVTERSLFCPL 299
G+ + + F +L LV +H+ L L
Sbjct: 191 DGKVYVT-AESRFSTLAELVHHHSTVADGLVTTL 223
>gi|239746599 PREDICTED: hypothetical protein XP_002343795 [Homo
sapiens]
Length = 443
Score = 30.8 bits (68), Expect = 1.8
Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 1/78 (1%)
Query: 81 GEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAEGLVGSGKELPESEGRARHAR 140
GE+ L P +G V+ G + + H S R PA +G+ +SE A AR
Sbjct: 222 GELGLFPQCPAGAAVQPREGPSDIRERSHTEASARFRPASRGNDTGRPGLQSEAGALRAR 281
Query: 141 LGNPYCSPTLVRKKAIRS 158
+ + S LV+ KA+RS
Sbjct: 282 IW-IHDSTCLVKAKALRS 298
>gi|13376439 ubiquitin domain containing 1 [Homo sapiens]
Length = 227
Score = 30.8 bits (68), Expect = 1.8
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 6/64 (9%)
Query: 53 LLCRSFQLAYLLQHPEERA--QPEPCPGPTGEVPLKPLSSSGGLVR----EPFGRDQLSQ 106
+ C S + LL+H EE + PEP P E PLK S+G VR P QL +
Sbjct: 117 IYCLSPPVNLLLEHTEEESLEPPEPPPSVRREFPLKVRLSTGKDVRLSASLPDTVGQLKR 176
Query: 107 NVHA 110
+HA
Sbjct: 177 QLHA 180
>gi|239758139 PREDICTED: hypothetical protein [Homo sapiens]
Length = 66
Score = 30.0 bits (66), Expect = 3.1
Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 1/31 (3%)
Query: 58 FQLAYLLQHPEERAQPE-PCPGPTGEVPLKP 87
F L L+ H A+PE PCP P G +P +P
Sbjct: 11 FSLGLLVLHVVAPAKPEGPCPPPPGPLPYRP 41
>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo
sapiens]
Length = 858
Score = 30.0 bits (66), Expect = 3.1
Identities = 33/116 (28%), Positives = 46/116 (39%), Gaps = 13/116 (11%)
Query: 59 QLAYLLQHPEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGR---DQLSQNVHALVSFR 115
QL LQ + QP+P P P G P+ +G L EP G D L F
Sbjct: 179 QLPQTLQPQPPQPQPDPPPVPPGPTPV----PTGLLEPEPGGSEDCDVLEATQPLEQGFL 234
Query: 116 RLPAEGLVGSGKELP---ESEGRARHARLGNPYCSPTLVR---KKAIRSKVIRSGA 165
+ EG SG+ P E E + R G + + + K+ +R K + S A
Sbjct: 235 QQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNA 290
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,221,911
Number of Sequences: 37866
Number of extensions: 851755
Number of successful extensions: 2772
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 2747
Number of HSP's gapped (non-prelim): 59
length of query: 339
length of database: 18,247,518
effective HSP length: 103
effective length of query: 236
effective length of database: 14,347,320
effective search space: 3385967520
effective search space used: 3385967520
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.