Guide to the Human Genome
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Name: SRMS Sequence: fasta or formatted (488aa) NCBI GI: 18250298
Description:

src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.2         40           2
 C cysteine            2.5         12           1
 D aspartate           3.5         17           2
 E glutamate           6.8         33           2
 F phenylalanine       4.1         20           2
 G glycine             8.0         39           3
 H histidine           2.5         12           1
 I isoleucine          2.9         14           1
 K lysine              4.1         20           1
 L leucine            12.7         62           3
 M methionine          1.8          9           1
 N asparagine          1.8          9           1
 P proline             8.2         40           2
 Q glutamine           4.1         20           2
 R arginine            7.2         35           3
 S serine              7.0         34           4
 T threonine           3.5         17           1
 V valine              5.7         28           2
 W tryptophan          2.0         10           1
 Y tyrosine            3.5         17           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   src-related kinase lacking C-terminal regulatory tyr... 
FRK                   0.359   fyn-related kinase 
PTK6                  0.348   PTK6 protein tyrosine kinase 6 
LCK                   0.348   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.348   lymphocyte-specific protein tyrosine kinase precurs...
HCK                   0.348   hemopoietic cell kinase isoform p61HCK 
FGR                   0.340   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.340   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.340   proto-oncogene tyrosine-protein kinase FGR 
FYN                   0.336   protein-tyrosine kinase fyn isoform a 
SRC                   0.335   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.335   proto-oncogene tyrosine-protein kinase SRC 
BLK                   0.335   B lymphoid tyrosine kinase 
LYN                   0.331   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
FYN                   0.329   protein-tyrosine kinase fyn isoform b 
YES1                  0.329   viral oncogene yes-1 homolog 1 
LYN                   0.328   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
ABL1                  0.292   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.292   c-abl oncogene 1, receptor tyrosine kinase isoform b...
FYN                   0.287   protein-tyrosine kinase fyn isoform c 
ABL2                  0.285   arg tyrosine kinase isoform c 
ABL2                  0.285   arg tyrosine kinase isoform b 
ABL2                  0.285   arg tyrosine kinase isoform e 
ABL2                  0.285   arg tyrosine kinase isoform d 
ABL2                  0.285   arg tyrosine kinase isoform a 
TEC                   0.257   tec protein tyrosine kinase 
TXK                   0.255   TXK tyrosine kinase 
ITK                   0.252   IL2-inducible T-cell kinase 
BTK                   0.248   Bruton agammaglobulinemia tyrosine kinase 
FER                   0.238   fer (fps/fes related) tyrosine kinase 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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