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Search of human proteins with 156627571
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156627571 sorbitol dehydrogenase [Homo sapiens]
(357 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156627571 sorbitol dehydrogenase [Homo sapiens] 724 0.0
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa... 100 3e-21
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa... 94 2e-19
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa... 93 4e-19
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap... 92 7e-19
gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit ... 88 1e-17
gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo s... 82 6e-16
gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens] 79 8e-15
gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens] 77 2e-14
gi|194239674 crystallin, zeta isoform a [Homo sapiens] 62 6e-10
gi|13236495 crystallin, zeta isoform a [Homo sapiens] 62 6e-10
gi|18379349 vesicle amine transport protein 1 [Homo sapiens] 50 4e-06
gi|24308257 vesicle amine transport protein 1 homolog (T. califo... 48 2e-05
gi|194239676 crystallin, zeta isoform b [Homo sapiens] 48 2e-05
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa... 48 2e-05
gi|28557745 zinc binding alcohol dehydrogenase domain containing... 44 2e-04
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a... 39 0.009
gi|197927207 crystallin, zeta isoform c [Homo sapiens] 39 0.009
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens] 37 0.021
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens] 37 0.021
gi|122939153 nicotinamide nucleotide transhydrogenase [Homo sapi... 33 0.30
gi|122939155 nicotinamide nucleotide transhydrogenase [Homo sapi... 33 0.30
gi|239752423 PREDICTED: hypothetical protein [Homo sapiens] 30 3.3
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b... 30 3.3
gi|24797097 pyrroline-5-carboxylate reductase 1 isoform 1 [Homo ... 30 4.3
gi|24797095 pyrroline-5-carboxylate reductase 1 isoform 2 [Homo ... 30 4.3
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 30 4.3
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 30 4.3
gi|224994173 roundabout 1 isoform d [Homo sapiens] 29 5.7
gi|224994171 roundabout 1 isoform c [Homo sapiens] 29 5.7
>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
Length = 357
Score = 724 bits (1870), Expect = 0.0
Identities = 357/357 (100%), Positives = 357/357 (100%)
Query: 1 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF 60
MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF
Sbjct: 1 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF 60
Query: 61 IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFC 120
IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFC
Sbjct: 61 IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFC 120
Query: 121 ATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCG 180
ATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCG
Sbjct: 121 ATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCG 180
Query: 181 AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL 240
AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL
Sbjct: 181 AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL 240
Query: 241 GCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRY 300
GCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRY
Sbjct: 241 GCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRY 300
Query: 301 CNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP 357
CNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP
Sbjct: 301 CNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP 357
>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
sapiens]
Length = 375
Score = 100 bits (248), Expect = 3e-21
Identities = 96/363 (26%), Positives = 156/363 (42%), Gaps = 49/363 (13%)
Query: 22 LENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGS 81
+E + P +EV ++M +VGICG+D H G + P++LGHEA+G VE VG
Sbjct: 24 IEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS----GTMVTPLPVILGHEAAGIVESVGE 79
Query: 82 SVKHLKPGDRVAIEPGAPR----------------ENDEFCKMGRYNLSPSIFFCATPPD 125
V +KPGD+V I P+ +ND G S F C P
Sbjct: 80 GVTTVKPGDKV-IPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKP- 137
Query: 126 DGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGVTLGH 174
+ F + Y + D + PL S G A VT G
Sbjct: 138 ---IHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGS 194
Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQEI 232
V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + Q K+ QE+
Sbjct: 195 TCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEV 254
Query: 233 ARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSE-----MTTVPLL 285
+++ +G + + + E G ++ A + G V+VG+ + M + LL
Sbjct: 255 LKEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLL 310
Query: 286 HAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLK 345
+ I G F+ P ++ +K ++ L+TH P EK E F+ G ++
Sbjct: 311 TGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIR 370
Query: 346 IML 348
+L
Sbjct: 371 TIL 373
>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
sapiens]
Length = 375
Score = 94.0 bits (232), Expect = 2e-19
Identities = 92/362 (25%), Positives = 156/362 (43%), Gaps = 47/362 (12%)
Query: 22 LENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGS 81
+E + P +EV ++M + GIC SD H GN + P++LGHEA+G VE VG
Sbjct: 24 IEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS----GNLVTPLPVILGHEAAGIVESVGE 79
Query: 82 SVKHLKPGDRVA---------------IEPGAPRENDEFCKMGRYNLSPSIFFCATPPDD 126
V +KPGD+V E +ND G F C+ P
Sbjct: 80 GVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP-- 137
Query: 127 GNLCRFYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGVTLGHK 175
+ F + Y + D + PL S G A + VT G
Sbjct: 138 --IHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGST 195
Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQEIA 233
V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + Q K+ QE+
Sbjct: 196 CAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255
Query: 234 RKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSE-----MTTVPLLH 286
+++ +G + + + E G ++ A + G V+VG+ + + + LL
Sbjct: 256 KEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLT 311
Query: 287 AAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKI 346
+ I G F+ + P ++ +K ++ L+T+ P EK E F+ + G ++
Sbjct: 312 GRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRT 371
Query: 347 ML 348
+L
Sbjct: 372 VL 373
>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
sapiens]
Length = 375
Score = 92.8 bits (229), Expect = 4e-19
Identities = 97/365 (26%), Positives = 159/365 (43%), Gaps = 53/365 (14%)
Query: 22 LENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGS 81
+E+ + P EV ++M +VGIC +D H GN + P++LGHEA+G VE VG
Sbjct: 24 IEDVEVAPPKAYEVRIKMVAVGICHTDDHVVS----GNLVTPLPVILGHEAAGIVESVGE 79
Query: 82 SVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGN------------L 129
V +KPGD+V I P+ C R +P +C D GN
Sbjct: 80 GVTTVKPGDKV-IPLFTPQ-----CGKCRVCKNPESNYC-LKNDLGNPRGTLQDGTRRFT 132
Query: 130 CR------FYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGVTL 172
CR F + Y + D + PL S G A VT
Sbjct: 133 CRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192
Query: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQ 230
G V G G +G+ ++ KA GAA+++ D++ + +KAKE+GA + Q K+ Q
Sbjct: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252
Query: 231 EIARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGL---GSEMTTVPLL 285
E+ +++ +G + + + E G ++ A + G V+VG+ ++ P+L
Sbjct: 253 EVLKEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPML 308
Query: 286 HAAIR--EVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLG 343
R + + G F+ P ++ +K ++ L+TH P EK E F+ G
Sbjct: 309 LLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKS 368
Query: 344 LKIML 348
++ +L
Sbjct: 369 IRTVL 373
>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo
sapiens]
Length = 380
Score = 92.0 bits (227), Expect = 7e-19
Identities = 88/364 (24%), Positives = 160/364 (43%), Gaps = 42/364 (11%)
Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79
L +E + P +EV +++ + +C +D + G + P+++GHEA+G VE +
Sbjct: 22 LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG---LAFPVIVGHEAAGIVESI 78
Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNL---------C 130
G V ++KPGD+V +FC NL I +P D L C
Sbjct: 79 GPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTC 138
Query: 131 R------FYKHNAAFCY---------KLPDNVTFEEGALIE-PLSVGIHAC-RRGGVTLG 173
+ F+ + Y K+ D+ E L+ S G A VT G
Sbjct: 139 KGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPG 198
Query: 174 HKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL---QISKESPQ 230
V G G +G+ ++ KA GA++++ D+++ + KAK +GA L + K +
Sbjct: 199 STCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQE 258
Query: 231 EIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGL--GSEMTTV---PL 284
I +G + + ++C G +++A + T +G G+ +G+ GS+ T+ L
Sbjct: 259 VIIELTKGGV----DFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEEL 314
Query: 285 LHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL 344
+ G ++ ++ P ++ +K N+ LVTH P +K EAF+ +G +
Sbjct: 315 IIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSV 374
Query: 345 KIML 348
+ +L
Sbjct: 375 RTIL 378
>gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit
[Homo sapiens]
Length = 386
Score = 88.2 bits (217), Expect = 1e-17
Identities = 89/354 (25%), Positives = 151/354 (42%), Gaps = 32/354 (9%)
Query: 22 LENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGS 81
+E + P EV +++ + GIC +D H + G + K P+++GHEA+G VE +G
Sbjct: 36 IEEIEVAPPKTKEVRIKILATGICRTDDHVIK----GTMVSKFPVIVGHEATGIVESIGE 91
Query: 82 SVKHLKPGDRV-------AIEPGAPREND-------EFCKMGRYNLSPSIFFCATPP--- 124
V +KPGD+V E A R D + G + F C P
Sbjct: 92 GVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHH 151
Query: 125 --DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIE-PLSVGIHAC-RRGGVTLGHKVLVCG 180
+ + + + K+ D E+ LI S G A + G V G +V G
Sbjct: 152 FMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFG 211
Query: 181 AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL 240
G +G+ ++ K+ GA++++ DL+ + KA +GA + K+S + I+ +
Sbjct: 212 LGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS-PKDSTKPISEVLSEMT 270
Query: 241 GCKPEVTIECTG-AEASIQAGIYATRSGGNLVLVGL---GSEMTTVPLLHAAIR--EVDI 294
G T E G E I A + G V+VG+ +T P+L R + +
Sbjct: 271 GNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCV 330
Query: 295 KGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 348
G + + P ++ +K ++ L+TH P +K E FE G ++ +L
Sbjct: 331 FGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVL 384
>gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo
sapiens]
Length = 374
Score = 82.4 bits (202), Expect = 6e-16
Identities = 89/366 (24%), Positives = 158/366 (43%), Gaps = 48/366 (13%)
Query: 20 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 79
L +E + P +EV +++ + +C +D + P++LGHE +G VE V
Sbjct: 20 LSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCF---PVILGHEGAGIVESV 76
Query: 80 GSSVKHLKPGDRVAIEPGAPREND-EFCKMGRYNLSPSIFFC---ATPPD-------DGN 128
G V LK GD V I P+ + +FC + NL I PD G
Sbjct: 77 GEGVTKLKAGDTV-IPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGK 135
Query: 129 LCRFYKHNAAFC-YKLPDNVTFEEGALIEPLSVGIHACRRG-GVTLGHKV---------- 176
Y + F Y + +++ A I+PL+ C G G++ G+
Sbjct: 136 TILHYMGTSTFSEYTVVADISV---AKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPG 192
Query: 177 ---LVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIA 233
V G G +G+ ++ K GA++++ D++ + ++AKE GA + +PQ+ +
Sbjct: 193 SVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI-----NPQDFS 247
Query: 234 RKVEGQL----GCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGL---GSEMTTVP-- 283
+ ++ L + + EC G ++A + A G G V+VG+ G E+ T P
Sbjct: 248 KPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQ 307
Query: 284 LLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLG 343
L+ + G ++ + P +S SK + V VTH ++ +AFE G
Sbjct: 308 LVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKS 367
Query: 344 LKIMLK 349
++ ++K
Sbjct: 368 IRTVVK 373
>gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]
Length = 375
Score = 78.6 bits (192), Expect = 8e-15
Identities = 86/363 (23%), Positives = 154/363 (42%), Gaps = 49/363 (13%)
Query: 22 LENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGS 81
+E + P EV +++ + G+CG+++ + + P +LGHE +G VE +G
Sbjct: 24 IEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLD---LLYPTILGHEGAGIVESIGE 80
Query: 82 SVKHLKPGDRVAIE--------PGAPRENDEFC---KMGRYNL---SPSIFFCATPPDDG 127
V +KPGD+V FC K + L S F C G
Sbjct: 81 GVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFTCK-----G 135
Query: 128 NLCRFYKHNAAFC-YKLPDNVTFEEGALIEPL----------SVGIHAC-RRGGVTLGHK 175
+ + + FC Y + ++ + + PL S G A VT G
Sbjct: 136 KSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGST 195
Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARK 235
V G G +G+ ++ KA GAA+++ D++ + KA+E+GA L +PQ++ +
Sbjct: 196 CAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECL-----NPQDLKKP 250
Query: 236 VEGQLGCKPEVTIE-CTGAEASIQ----AGIYATRSGGNLVLVGL---GSEMTTVPLLHA 287
++ L + I+ C A ++ A S G V+VG+ ++ L
Sbjct: 251 IQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPASVQLKISGQLFF 310
Query: 288 AIREV--DIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLK 345
+ R + + G ++ P ++ ++ +N+ PL+TH L+K EA E K G ++
Sbjct: 311 SGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEAVELMKTGKCIR 370
Query: 346 IML 348
+L
Sbjct: 371 CIL 373
>gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]
Length = 368
Score = 77.4 bits (189), Expect = 2e-14
Identities = 85/356 (23%), Positives = 150/356 (42%), Gaps = 49/356 (13%)
Query: 22 LENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGS 81
+E + P EV +++ + G+CG+++ + + P +LGHE +G VE +G
Sbjct: 24 IEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLD---LLYPTILGHEGAGIVESIGE 80
Query: 82 SVKHLKPGDRVAIE--------PGAPRENDEFC---KMGRYNL---SPSIFFCATPPDDG 127
V +KPGD+V FC K + L S F C G
Sbjct: 81 GVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSKTQLMSDGTSRFTCK-----G 135
Query: 128 NLCRFYKHNAAFC-YKLPDNVTFEEGALIEPL----------SVGIHAC-RRGGVTLGHK 175
+ + + FC Y + ++ + + PL S G A VT G
Sbjct: 136 KSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTGFGAAINTAKVTPGST 195
Query: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARK 235
V G G +G+ ++ KA GAA+++ D++ + KA+E+GA L +PQ++ +
Sbjct: 196 CAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATECL-----NPQDLKKP 250
Query: 236 VEGQLGCKPEVTIE-CTGAEASIQ----AGIYATRSGGNLVLVGL---GSEMTTVPLLHA 287
++ L + I+ C A ++ A S G V+VG+ ++ L
Sbjct: 251 IQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPASVQLKISGQLFF 310
Query: 288 AIREV--DIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 341
+ R + + G ++ P ++ ++ +N+ PL+TH L+K EA E K G
Sbjct: 311 SGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEAVELMKTG 366
>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 62.4 bits (150), Expect = 6e-10
Identities = 82/339 (24%), Positives = 139/339 (41%), Gaps = 47/339 (13%)
Query: 16 GPGDLRLEN-YPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PMVLGHEA 72
GP L+L + +P P ++VL+++H+ G+ + Y R G + K P G +
Sbjct: 18 GPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVET----YIRSGTYSRKPLLPYTPGSDV 73
Query: 73 SGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRF 132
+G +E VG + K GDRV E+ + +
Sbjct: 74 AGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTV------------------- 114
Query: 133 YKHNAAFCYKLPDNVTFEEGALIE-PLSVGIHACRRGG-VTLGHKVLVCGA-GPIGMVTL 189
YKLP+ + F++GA I P A V G VLV GA G +G+
Sbjct: 115 --------YKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAAC 166
Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 249
+A+A G +++ T + + GA V + + + +K G+ G ++ IE
Sbjct: 167 QIARAYGL-KILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGI--DIIIE 223
Query: 250 CTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNT----WP 305
A ++ + GG +++VG + P A +E I GV + +T
Sbjct: 224 ML-ANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMA-KESSIIGVTLFSSTKEEFQQ 281
Query: 306 VAISMLASKSVN-VKPLVTHRFPLEKALEAFETFKKGLG 343
A ++ A + +KP++ ++PLEK EA E G G
Sbjct: 282 YAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSG 320
>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 62.4 bits (150), Expect = 6e-10
Identities = 82/339 (24%), Positives = 139/339 (41%), Gaps = 47/339 (13%)
Query: 16 GPGDLRLEN-YPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PMVLGHEA 72
GP L+L + +P P ++VL+++H+ G+ + Y R G + K P G +
Sbjct: 18 GPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVET----YIRSGTYSRKPLLPYTPGSDV 73
Query: 73 SGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRF 132
+G +E VG + K GDRV E+ + +
Sbjct: 74 AGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTV------------------- 114
Query: 133 YKHNAAFCYKLPDNVTFEEGALIE-PLSVGIHACRRGG-VTLGHKVLVCGA-GPIGMVTL 189
YKLP+ + F++GA I P A V G VLV GA G +G+
Sbjct: 115 --------YKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAAC 166
Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 249
+A+A G +++ T + + GA V + + + +K G+ G ++ IE
Sbjct: 167 QIARAYGL-KILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGI--DIIIE 223
Query: 250 CTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNT----WP 305
A ++ + GG +++VG + P A +E I GV + +T
Sbjct: 224 ML-ANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMA-KESSIIGVTLFSSTKEEFQQ 281
Query: 306 VAISMLASKSVN-VKPLVTHRFPLEKALEAFETFKKGLG 343
A ++ A + +KP++ ++PLEK EA E G G
Sbjct: 282 YAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSG 320
>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
Length = 393
Score = 49.7 bits (117), Expect = 4e-06
Identities = 66/250 (26%), Positives = 106/250 (42%), Gaps = 52/250 (20%)
Query: 2 AAAAKPNNLSLVVHGPGD---LRLENYPI--PEPGPNEVLLRMHSVGICGSDVHYWEYGR 56
AAA+ P LV+ G G ++L++ P P PGP ++ LR+ + G+ +D+ R
Sbjct: 41 AAASPPLLRCLVLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADL----MAR 96
Query: 57 IGNF--IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLS 114
G + + P+ G E +G V VG V K GDRV + + +E
Sbjct: 97 QGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLNRSGMWQEE---------- 146
Query: 115 PSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGA--LIEPLSVGIHACRRGGVTL 172
T P + + +P+ +TFEE A L+ ++ + G +
Sbjct: 147 ------VTVP------------SVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQP 188
Query: 173 GHKVLV-CGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIG---------ADLVL 222
GH VLV AG +GM + + + + V T SA++ KE G D V
Sbjct: 189 GHSVLVHMAAGGVGMAAVQLCRTVENVTVFGT-ASASKHEALKENGVTHPIDYHTTDYVD 247
Query: 223 QISKESPQEI 232
+I K SP+ +
Sbjct: 248 EIKKISPKGV 257
>gi|24308257 vesicle amine transport protein 1 homolog (T.
californica)-like [Homo sapiens]
Length = 419
Score = 47.8 bits (112), Expect = 2e-05
Identities = 43/138 (31%), Positives = 60/138 (43%), Gaps = 30/138 (21%)
Query: 16 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGT 75
G LRL +PEP E+ +R+ + G+ D+ + G I N K P+V G E SG
Sbjct: 52 GLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQ-GNIDN-PPKTPLVPGFECSGI 109
Query: 76 VEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKH 135
VE +G SVK + GDRV M N + TP +
Sbjct: 110 VEALGDSVKGYEIGDRV---------------MAFVNYNAWAEVVCTPVE---------- 144
Query: 136 NAAFCYKLPDNVTFEEGA 153
F YK+PD+++F E A
Sbjct: 145 ---FVYKIPDDMSFSEAA 159
>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
Length = 295
Score = 47.8 bits (112), Expect = 2e-05
Identities = 79/339 (23%), Positives = 127/339 (37%), Gaps = 81/339 (23%)
Query: 16 GPGDLRLEN-YPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKK--PMVLGHEA 72
GP L+L + +P P ++VL+++H+ G+ + Y R G + K P G +
Sbjct: 18 GPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVET----YIRSGTYSRKPLLPYTPGSDV 73
Query: 73 SGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRF 132
+G +E VG + K GDRV E+ + +
Sbjct: 74 AGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTV------------------- 114
Query: 133 YKHNAAFCYKLPDNVTFEEGALIE-PLSVGIHACRRGG-VTLGHKVLVCGA-GPIGMVTL 189
YKLP+ + F++GA I P A V G VLV GA G +G+
Sbjct: 115 --------YKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAAC 166
Query: 190 LVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 249
+A+A G + + + T E G +VLQ E+ E K I+
Sbjct: 167 QIARAYG---LKILGTAGT------EEGQKIVLQ---NGAHEVFNHREVNYIDK----IK 210
Query: 250 CTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNT----WP 305
G+ +I+ T + +E I GV + +T
Sbjct: 211 VVGSRGTIEINPRDTMA-----------------------KESSIIGVTLFSSTKEEFQQ 247
Query: 306 VAISMLASKSVN-VKPLVTHRFPLEKALEAFETFKKGLG 343
A ++ A + +KP++ ++PLEK EA E G G
Sbjct: 248 YAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSG 286
>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
sapiens]
Length = 396
Score = 47.8 bits (112), Expect = 2e-05
Identities = 54/220 (24%), Positives = 89/220 (40%), Gaps = 48/220 (21%)
Query: 32 PNEVLLRMHSVGICGSDVHYWE-YGRIGNFIVKKPM-----------VLGHEASGTVEKV 79
PNEV++++H+ + DV+ YG + + P+ LG + SG V +
Sbjct: 71 PNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMEC 130
Query: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPP-DDGNLCRFYKHNAA 138
G VK+ KPGD V + A PP G L F +
Sbjct: 131 GLDVKYFKPGDEV--------------------------WAAVPPWKQGTLSEFVVVSGN 164
Query: 139 FCYKLPDNVTFEEGALIEPLSVGIHAC--RRGGVT----LGHKVLVCGA-GPIGMVTLLV 191
P ++T + A + +++ + + GG+ G +VL+ GA G +G + V
Sbjct: 165 EVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQV 224
Query: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQE 231
KA A V A+ L +++GAD V+ S +E
Sbjct: 225 MKAWDAHVTAVCSQDASEL--VRKLGADDVIDYKSGSVEE 262
>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
[Homo sapiens]
Length = 377
Score = 44.3 bits (103), Expect = 2e-04
Identities = 62/257 (24%), Positives = 98/257 (38%), Gaps = 36/257 (14%)
Query: 26 PIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKH 85
P+P PG ++L+R VG+ SD++Y GR + VK P +G E G V +G S
Sbjct: 56 PVPLPGDGDLLVRNRFVGVNASDINY-SAGRY-DPSVKPPFDIGFEGIGEVVALGLSAS- 112
Query: 86 LKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPD 145
RY + ++ + A G+ + A+ +P
Sbjct: 113 -----------------------ARYTVGQAVAYMA----PGSFAEYTVVPASIATPVPS 145
Query: 146 NVTFEEGALIEPLSVGIHACRRGGVTLGHKVLV-CGAGPIGMVTLLVAKAMGAAQVVVTD 204
L+ + I GG++ G KVLV AG G + ++K V+ T
Sbjct: 146 VKPEYLTLLVSGTTAYISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSK-KAKCHVIGTC 204
Query: 205 LSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYAT 264
S + + K +G D + K P K E G +V E G A + A
Sbjct: 205 SSDEKSAFLKSLGCDRPINY-KTEPVGTVLKQEYPEGV--DVVYESVGG-AMFDLAVDAL 260
Query: 265 RSGGNLVLVGLGSEMTT 281
+ G L+++G S T
Sbjct: 261 ATKGRLIVIGFISGYQT 277
>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
[Homo sapiens]
Length = 373
Score = 38.5 bits (88), Expect = 0.009
Identities = 32/96 (33%), Positives = 53/96 (55%), Gaps = 7/96 (7%)
Query: 2 AAAAKPNNLSLVVHGP-GD----LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGR 56
+A+A+P + +V+G GD + L+N + ++V ++M + I SD++ + G
Sbjct: 35 SASAEPARVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQ-GN 93
Query: 57 IGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRV 92
G F+ + P V G+E V VGS+V LKPGD V
Sbjct: 94 YG-FLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWV 128
>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
Length = 192
Score = 38.5 bits (88), Expect = 0.009
Identities = 47/188 (25%), Positives = 82/188 (43%), Gaps = 11/188 (5%)
Query: 162 IHACRRGGVTLGHKVLVCGA-GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADL 220
+H V G VLV GA G +G+ +A+A G +++ T + + GA
Sbjct: 1 MHLLSSACVKAGESVLVHGASGGVGLAACQIARAYGL-KILGTAGTEEGQKIVLQNGAHE 59
Query: 221 VLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMT 280
V + + + +K G+ G ++ IE A ++ + GG +++VG +
Sbjct: 60 VFNHREVNYIDKIKKYVGEKGI--DIIIEML-ANVNLSKDLSLLSHGGRVIVVGSRGTIE 116
Query: 281 TVPLLHAAIREVDIKGVFRYCNT----WPVAISMLASKSVN-VKPLVTHRFPLEKALEAF 335
P A +E I GV + +T A ++ A + +KP++ ++PLEK EA
Sbjct: 117 INPRDTMA-KESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAH 175
Query: 336 ETFKKGLG 343
E G G
Sbjct: 176 ENIIHGSG 183
>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 37.4 bits (85), Expect = 0.021
Identities = 61/267 (22%), Positives = 100/267 (37%), Gaps = 44/267 (16%)
Query: 16 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVK--KPMVLGHEAS 73
GP +L ++ P PG EVLL++ + + +D+ R G + +LG EAS
Sbjct: 11 GPENLYVKEVAKPSPGEGEVLLKVAASALNRADL----MQRQGQYDPPPGASNILGLEAS 66
Query: 74 GTVEKVGSSVK-HLKPGD-RVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCR 131
G V ++G + H K GD +A+ PG G +
Sbjct: 67 GHVAELGPGCQGHWKIGDTAMALLPG-----------------------------GGQAQ 97
Query: 132 FYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR--GGVTLGHKVLV-CGAGPIGMVT 188
+ +P+ +T + A I + G V G VL+ G +G
Sbjct: 98 YVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAA 157
Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248
+ + + GA +VT S +L A+++GA KE E K G + +
Sbjct: 158 IQLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKF--TKGAGVNLIL 214
Query: 249 ECTGAEASIQAGIYATRSGGNLVLVGL 275
+C G + + + G VL GL
Sbjct: 215 DCIGG-SYWEKNVNCLALDGRWVLYGL 240
>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 37.4 bits (85), Expect = 0.021
Identities = 61/267 (22%), Positives = 100/267 (37%), Gaps = 44/267 (16%)
Query: 16 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVK--KPMVLGHEAS 73
GP +L ++ P PG EVLL++ + + +D+ R G + +LG EAS
Sbjct: 11 GPENLYVKEVAKPSPGEGEVLLKVAASALNRADL----MQRQGQYDPPPGASNILGLEAS 66
Query: 74 GTVEKVGSSVK-HLKPGD-RVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCR 131
G V ++G + H K GD +A+ PG G +
Sbjct: 67 GHVAELGPGCQGHWKIGDTAMALLPG-----------------------------GGQAQ 97
Query: 132 FYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR--GGVTLGHKVLV-CGAGPIGMVT 188
+ +P+ +T + A I + G V G VL+ G +G
Sbjct: 98 YVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAA 157
Query: 189 LLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTI 248
+ + + GA +VT S +L A+++GA KE E K G + +
Sbjct: 158 IQLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKF--TKGAGVNLIL 214
Query: 249 ECTGAEASIQAGIYATRSGGNLVLVGL 275
+C G + + + G VL GL
Sbjct: 215 DCIGG-SYWEKNVNCLALDGRWVLYGL 240
>gi|122939153 nicotinamide nucleotide transhydrogenase [Homo
sapiens]
Length = 1086
Score = 33.5 bits (75), Expect = 0.30
Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 8/85 (9%)
Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIAR 234
K+L+ G G G+ + AK+MGA V D A L + K +GA+ + KES
Sbjct: 229 KILIVGGGVAGLASAGAAKSMGAI-VRGFDTRAAALEQFKSLGAEPLEVDLKESG----- 282
Query: 235 KVEGQLGCKPEVTIECTGAEASIQA 259
EGQ G E++ E AE + A
Sbjct: 283 --EGQGGYAKEMSKEFIEAEMKLFA 305
>gi|122939155 nicotinamide nucleotide transhydrogenase [Homo
sapiens]
Length = 1086
Score = 33.5 bits (75), Expect = 0.30
Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 8/85 (9%)
Query: 175 KVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIAR 234
K+L+ G G G+ + AK+MGA V D A L + K +GA+ + KES
Sbjct: 229 KILIVGGGVAGLASAGAAKSMGAI-VRGFDTRAAALEQFKSLGAEPLEVDLKESG----- 282
Query: 235 KVEGQLGCKPEVTIECTGAEASIQA 259
EGQ G E++ E AE + A
Sbjct: 283 --EGQGGYAKEMSKEFIEAEMKLFA 305
>gi|239752423 PREDICTED: hypothetical protein [Homo sapiens]
Length = 199
Score = 30.0 bits (66), Expect = 3.3
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 6/59 (10%)
Query: 77 EKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCA----TPPDDGNLCR 131
E VG +VK L G+RV P R D + G Y L P++ C+ T LCR
Sbjct: 127 ESVGIAVKRLGKGNRVP--PATRRRPDRQGQEGLYQLHPTVHRCSSLRWTSMGSTRLCR 183
>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
[Homo sapiens]
Length = 297
Score = 30.0 bits (66), Expect = 3.3
Identities = 16/33 (48%), Positives = 20/33 (60%)
Query: 60 FIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRV 92
F+ + P V G+E V VGS+V LKPGD V
Sbjct: 20 FLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWV 52
>gi|24797097 pyrroline-5-carboxylate reductase 1 isoform 1 [Homo
sapiens]
Length = 319
Score = 29.6 bits (65), Expect = 4.3
Identities = 32/136 (23%), Positives = 51/136 (37%), Gaps = 7/136 (5%)
Query: 107 KMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACR 166
K+ + +P + C T A Y + E+G L+E L + C
Sbjct: 107 KLSAFRPAPRVIRCMTNTP------VVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCT 160
Query: 167 RGGVTLGHKVL-VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQIS 225
L V + G+GP T L A A G ++ + A RL +GA +L S
Sbjct: 161 EVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHS 220
Query: 226 KESPQEIARKVEGQLG 241
++ P ++ V G
Sbjct: 221 EQHPGQLKDNVSSPGG 236
>gi|24797095 pyrroline-5-carboxylate reductase 1 isoform 2 [Homo
sapiens]
Length = 316
Score = 29.6 bits (65), Expect = 4.3
Identities = 32/136 (23%), Positives = 51/136 (37%), Gaps = 7/136 (5%)
Query: 107 KMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACR 166
K+ + +P + C T A Y + E+G L+E L + C
Sbjct: 107 KLSAFRPAPRVIRCMTNTP------VVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCT 160
Query: 167 RGGVTLGHKVL-VCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQIS 225
L V + G+GP T L A A G ++ + A RL +GA +L S
Sbjct: 161 EVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHS 220
Query: 226 KESPQEIARKVEGQLG 241
++ P ++ V G
Sbjct: 221 EQHPGQLKDNVSSPGG 236
>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
Length = 2603
Score = 29.6 bits (65), Expect = 4.3
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 202 VTDLSATRLSKAKEIGADLVLQISKES-PQEIARKVEGQLGCKPEVTIECTGAEASIQAG 260
+T S R K +E ++V + K S P + +V G+ GC E TGA I
Sbjct: 1705 LTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNINAIREFTGAHIDIDK- 1763
Query: 261 IYATRSGGNLVLVGLGSEMT--TVPLLHAAIREVD 293
++G ++ + G+E T L++A I++ D
Sbjct: 1764 -QKDKTGDRIITIRGGTESTRQATQLINALIKDPD 1797
>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
Length = 2352
Score = 29.6 bits (65), Expect = 4.3
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 202 VTDLSATRLSKAKEIGADLVLQISKES-PQEIARKVEGQLGCKPEVTIECTGAEASIQAG 260
+T S R K +E ++V + K S P + +V G+ GC E TGA I
Sbjct: 1454 LTVASPKRGQKREEGWKEVVRRSKKVSVPSTVISRVIGRGGCNINAIREFTGAHIDIDK- 1512
Query: 261 IYATRSGGNLVLVGLGSEMT--TVPLLHAAIREVD 293
++G ++ + G+E T L++A I++ D
Sbjct: 1513 -QKDKTGDRIITIRGGTESTRQATQLINALIKDPD 1546
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 29.3 bits (64), Expect = 5.7
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 8/146 (5%)
Query: 188 TLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVT 247
TL + K T ++ + KA E A L +Q+ E P + + + + VT
Sbjct: 275 TLKIRKVTAGDMGSYTCVAENMVGKA-EASATLTVQVGSEPPHFVVKPRDQVVALGRTVT 333
Query: 248 IECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFR------YC 301
+C A + Q I+ R G +L ++ + ++ I V R C
Sbjct: 334 FQCE-ATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYIC 392
Query: 302 NTWPVAISMLASKSVNVKPLVTHRFP 327
T VA S++ + V ++ R P
Sbjct: 393 QTLNVAGSIITKAYLEVTDVIADRPP 418
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 29.3 bits (64), Expect = 5.7
Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 8/146 (5%)
Query: 188 TLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVT 247
TL + K T ++ + KA E A L +Q+ E P + + + + VT
Sbjct: 275 TLKIRKVTAGDMGSYTCVAENMVGKA-EASATLTVQVGSEPPHFVVKPRDQVVALGRTVT 333
Query: 248 IECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFR------YC 301
+C A + Q I+ R G +L ++ + ++ I V R C
Sbjct: 334 FQCE-ATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYIC 392
Query: 302 NTWPVAISMLASKSVNVKPLVTHRFP 327
T VA S++ + V ++ R P
Sbjct: 393 QTLNVAGSIITKAYLEVTDVIADRPP 418
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,399,772
Number of Sequences: 37866
Number of extensions: 659341
Number of successful extensions: 1352
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1300
Number of HSP's gapped (non-prelim): 61
length of query: 357
length of database: 18,247,518
effective HSP length: 103
effective length of query: 254
effective length of database: 14,347,320
effective search space: 3644219280
effective search space used: 3644219280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.