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Search of human proteins with 156231037
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156231037 kininogen 1 isoform 1 [Homo sapiens]
(644 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156231037 kininogen 1 isoform 1 [Homo sapiens] 1353 0.0
gi|4504893 kininogen 1 isoform 2 [Homo sapiens] 825 0.0
gi|20302139 cystatin F [Homo sapiens] 66 9e-11
gi|58331240 fetuin B [Homo sapiens] 66 1e-10
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 60 8e-09
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 60 8e-09
gi|4503113 cystatin M precursor [Homo sapiens] 55 2e-07
gi|4503107 cystatin C precursor [Homo sapiens] 53 1e-06
gi|4503105 cystatin SA precursor [Homo sapiens] 52 2e-06
gi|222080086 zinc transporter like 2 [Homo sapiens] 50 6e-06
gi|40255009 zinc transporter like 2 [Homo sapiens] 50 6e-06
gi|19882259 cystatin-like 1 precursor [Homo sapiens] 48 3e-05
gi|19882251 cystatin SN precursor [Homo sapiens] 46 9e-05
gi|4503109 cystatin S precursor [Homo sapiens] 46 1e-04
gi|60097902 filaggrin [Homo sapiens] 45 2e-04
gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens] 45 2e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 44 4e-04
gi|4504487 histidine rich calcium binding protein precursor [Hom... 44 4e-04
gi|59938776 cAMP responsive element binding protein 5 isoform de... 44 6e-04
gi|59938774 cAMP responsive element binding protein 5 isoform be... 44 6e-04
gi|59938772 cAMP responsive element binding protein 5 isoform ga... 44 6e-04
gi|59938770 cAMP responsive element binding protein 5 isoform al... 44 6e-04
gi|156523970 alpha-2-HS-glycoprotein [Homo sapiens] 43 8e-04
gi|57864582 hornerin [Homo sapiens] 42 0.001
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 40 0.009
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 40 0.009
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 40 0.009
gi|222418633 family with sequence similarity 71, member B [Homo ... 39 0.011
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 39 0.019
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 39 0.019
>gi|156231037 kininogen 1 isoform 1 [Homo sapiens]
Length = 644
Score = 1353 bits (3502), Expect = 0.0
Identities = 644/644 (100%), Positives = 644/644 (100%)
Query: 1 MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT 60
MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT
Sbjct: 1 MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT 60
Query: 61 EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS 120
EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS
Sbjct: 61 EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS 120
Query: 121 VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN 180
VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN
Sbjct: 121 VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN 180
Query: 181 EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR 240
EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR
Sbjct: 181 EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR 240
Query: 241 IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK 300
IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK
Sbjct: 241 IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK 300
Query: 301 IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW 360
IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW
Sbjct: 301 IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW 360
Query: 361 EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSG 420
EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSG
Sbjct: 361 EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSG 420
Query: 421 KEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLD 480
KEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLD
Sbjct: 421 KEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLD 480
Query: 481 DDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQE 540
DDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQE
Sbjct: 481 DDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQE 540
Query: 541 KTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSF 600
KTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSF
Sbjct: 541 KTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSF 600
Query: 601 NPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS 644
NPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS
Sbjct: 601 NPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS 644
>gi|4504893 kininogen 1 isoform 2 [Homo sapiens]
Length = 427
Score = 825 bits (2131), Expect = 0.0
Identities = 406/425 (95%), Positives = 407/425 (95%), Gaps = 9/425 (2%)
Query: 1 MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT 60
MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT
Sbjct: 1 MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT 60
Query: 61 EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS 120
EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS
Sbjct: 61 EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS 120
Query: 121 VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN 180
VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN
Sbjct: 121 VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN 180
Query: 181 EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR 240
EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR
Sbjct: 181 EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR 240
Query: 241 IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK 300
IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK
Sbjct: 241 IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK 300
Query: 301 IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW 360
IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW
Sbjct: 301 IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW 360
Query: 361 EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTV---------SPPHTSMAP 411
EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETT PP P
Sbjct: 361 EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTSHLRSCEYKGRPPKAGAEP 420
Query: 412 AQDEE 416
A + E
Sbjct: 421 ASERE 425
>gi|20302139 cystatin F [Homo sapiens]
Length = 167
Score = 66.2 bits (160), Expect = 9e-11
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Query: 261 TKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFID 320
+++ G P+ I TN P + + +++ K N N F FK + +A VQ+V G KY ++
Sbjct: 54 SRVKPGFPKTIKTNDPGVLQAARYSVEKFNNCTNDMFLFKESRITRALVQIVKGLKYMLE 113
Query: 321 FVARETTCSKESNEELTESCE---TKKLGQSLDCNAEVYVVPWEKKI-YPTVNC 370
TTC K + L + C+ L Q+L C +EV+VVPW + P + C
Sbjct: 114 VEIGRTTCKKNQHLRL-DDCDFQTNHTLKQTLSCYSEVWVVPWLQHFEVPVLRC 166
Score = 42.7 bits (99), Expect = 0.001
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 149 ISTQSPDLEPILRHGIQYFNNNTQHSSLFMLNEVKRAQRQVVAGLNFRITYSIVQTNCSK 208
I T P + R+ ++ FNN T LF + + RA Q+V GL + + I +T C K
Sbjct: 64 IKTNDPGVLQAARYSVEKFNNCTNDMFLFKESRITRALVQIVKGLKYMLEVEIGRTTCKK 123
Query: 209 ENFLFLTPDC 218
L L DC
Sbjct: 124 NQHLRL-DDC 132
Score = 31.2 bits (69), Expect = 3.1
Identities = 21/88 (23%), Positives = 36/88 (40%)
Query: 10 CSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRITEATKTVGSD 69
CS+ L S + + I ND + +A +++K+N+ F RIT A +
Sbjct: 48 CSQDLNSRVKPGFPKTIKTNDPGVLQAARYSVEKFNNCTNDMFLFKESRITRALVQIVKG 107
Query: 70 TFYSFKYEIKEGDCPVQSGKTWQDCEYK 97
Y + EI C DC+++
Sbjct: 108 LKYMLEVEIGRTTCKKNQHLRLDDCDFQ 135
>gi|58331240 fetuin B [Homo sapiens]
Length = 382
Score = 65.9 bits (159), Expect = 1e-10
Identities = 64/261 (24%), Positives = 107/261 (40%), Gaps = 19/261 (7%)
Query: 28 CNDKDLFKAVDAALKKYNSQNQSNNQFVLYRITEAT--KTVGSDTFYSFKYEIKEGDCPV 85
CND D+ AL+ N + L R+ +A + G + + ++ E DC V
Sbjct: 36 CNDSDVLAVAGFALRDINKDRKDGYVLRLNRVNDAQEYRRGGLGSLFYLTLDVLETDCHV 95
Query: 86 QSGKTWQDCEYKDAAKAATGECTATVGKRSSTK-FSVATQTCQITP-AEGPVVTAQYDCL 143
K WQDC + ++ G+C A + ++ +A C + P ++ + DC
Sbjct: 96 LRKKAWQDCGMRIFFESVYGQCKAIFYMNNPSRVLYLAAYNCTLRPVSKKKIYMTCPDCP 155
Query: 144 GCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLNEVKRAQRQVVAGLNFRITYSIVQ 203
+ S+ LE +Y N NT S + L +V RA Q V G ++ + Y I +
Sbjct: 156 SSIPTDSSNHQVLEAATESLAKYNNENT--SKQYSLFKVTRASSQWVVGPSYFVEYLIKE 213
Query: 204 TNCSKENFLFLTPDCKSLWNGDT---GECTDNAYIDIQLRIASFSQNCDIYPGKDFVQPP 260
+ C+K C SL + D+ G C + + S + CD + + P
Sbjct: 214 SPCTKSQ----ASSC-SLQSSDSVPVGLCKGSLTRTHWEKFVSVT--CDFFESQ---APA 263
Query: 261 TKICVGCPRDIPTNSPELEET 281
T PTN P++EE+
Sbjct: 264 TGSENSAVNQKPTNLPKVEES 284
Score = 58.5 bits (140), Expect = 2e-08
Identities = 55/227 (24%), Positives = 101/227 (44%), Gaps = 23/227 (10%)
Query: 155 DLEPILRHGIQYFNNNTQHSSLFMLNEVKRAQRQVVAGLN--FRITYSIVQTNCS---KE 209
D+ + ++ N + + + LN V AQ GL F +T +++T+C K+
Sbjct: 40 DVLAVAGFALRDINKDRKDGYVLRLNRVNDAQEYRRGGLGSLFYLTLDVLETDCHVLRKK 99
Query: 210 NFLFLTPDC--KSLWNGDTGECTDNAYIDIQLRIASFSQ-NCDIYPGKDFVQPPTKICVG 266
+ DC + + G+C Y++ R+ + NC + P + C
Sbjct: 100 AW----QDCGMRIFFESVYGQCKAIFYMNNPSRVLYLAAYNCTLRPVSK--KKIYMTCPD 153
Query: 267 CPRDIPTNSP--ELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFIDFVAR 324
CP IPT+S ++ E T ++ K N EN + Y + V +A Q V G YF++++ +
Sbjct: 154 CPSSIPTDSSNHQVLEAATESLAKYNNENTSKQY-SLFKVTRASSQWVVGPSYFVEYLIK 212
Query: 325 ETTCSKESNEELT-ESCETKKLGQSLDCNAEVYVVPWEKKIYPTVNC 370
E+ C+K + +S ++ +G C + WEK + +V C
Sbjct: 213 ESPCTKSQASSCSLQSSDSVPVGL---CKGSLTRTHWEK--FVSVTC 254
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 59.7 bits (143), Expect = 8e-09
Identities = 34/96 (35%), Positives = 40/96 (41%), Gaps = 19/96 (19%)
Query: 429 HDWGHEKQRKHNLGHGHKHER-DQGHGHQRGHGLG-------HGHEQQHGLGHGHKFKLD 480
HD H+ ++ GH H+H D HGH HG G HGH H GH H
Sbjct: 31 HDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSH----- 85
Query: 481 DDLEHQGGHVLDH------GHKHKHGHGHGKHKNKG 510
+DL H H H GH H H H HG + G
Sbjct: 86 EDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESG 121
Score = 57.0 bits (136), Expect = 5e-08
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 20/79 (25%)
Query: 424 GHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDL 483
GH+ H GH + ++ HGH H+ D GH H+ H HGH HG H + L
Sbjct: 57 GHSHAHGHGHTHE---SIWHGHTHDHDHGHSHEDLH---HGH--SHGYSH-------ESL 101
Query: 484 EHQGGHVLDHGHKHKHGHG 502
H+G HGH H+H HG
Sbjct: 102 YHRG-----HGHDHEHSHG 115
Score = 38.5 bits (88), Expect = 0.019
Identities = 32/112 (28%), Positives = 42/112 (37%), Gaps = 16/112 (14%)
Query: 443 HGHKHERDQGHGHQRGHGLGHGHEQQHGL----GHGHKFKLDDDLEH-QGGHVLDHGHKH 497
H H GHGH G G GL G ++ + H +GGH HGH H
Sbjct: 196 HSHHTLEQPGHGHSHS---GQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGH 252
Query: 498 KHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEGPTPIP 549
H H G H +G+ E +S E+ T Q K G + +P
Sbjct: 253 AHSHTRGSH-----GHGRQERSTKEKQSSEEEEKETRGVQ---KRRGGSTVP 296
Score = 35.4 bits (80), Expect = 0.16
Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 9/46 (19%)
Query: 458 GHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGH 503
GH H Q+ GH H+ +D HGH H HGHGH
Sbjct: 30 GHDDLHDDLQEDFHGHSHRHSHED---------FHHGHSHAHGHGH 66
Score = 32.0 bits (71), Expect = 1.8
Identities = 13/27 (48%), Positives = 14/27 (51%), Gaps = 3/27 (11%)
Query: 442 GHGHKHERDQGHGHQRGHGLGHGHEQQ 468
GHGH H H H RG HGH +Q
Sbjct: 243 GHGHSHGHGHAHSHTRG---SHGHGRQ 266
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 59.7 bits (143), Expect = 8e-09
Identities = 34/96 (35%), Positives = 40/96 (41%), Gaps = 19/96 (19%)
Query: 429 HDWGHEKQRKHNLGHGHKHER-DQGHGHQRGHGLG-------HGHEQQHGLGHGHKFKLD 480
HD H+ ++ GH H+H D HGH HG G HGH H GH H
Sbjct: 31 HDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSH----- 85
Query: 481 DDLEHQGGHVLDH------GHKHKHGHGHGKHKNKG 510
+DL H H H GH H H H HG + G
Sbjct: 86 EDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESG 121
Score = 57.0 bits (136), Expect = 5e-08
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 20/79 (25%)
Query: 424 GHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDL 483
GH+ H GH + ++ HGH H+ D GH H+ H HGH HG H + L
Sbjct: 57 GHSHAHGHGHTHE---SIWHGHTHDHDHGHSHEDLH---HGH--SHGYSH-------ESL 101
Query: 484 EHQGGHVLDHGHKHKHGHG 502
H+G HGH H+H HG
Sbjct: 102 YHRG-----HGHDHEHSHG 115
Score = 38.5 bits (88), Expect = 0.019
Identities = 32/112 (28%), Positives = 42/112 (37%), Gaps = 16/112 (14%)
Query: 443 HGHKHERDQGHGHQRGHGLGHGHEQQHGL----GHGHKFKLDDDLEH-QGGHVLDHGHKH 497
H H GHGH G G GL G ++ + H +GGH HGH H
Sbjct: 196 HSHHTLEQPGHGHSHS---GQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGH 252
Query: 498 KHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEGPTPIP 549
H H G H +G+ E +S E+ T Q K G + +P
Sbjct: 253 AHSHTRGSH-----GHGRQERSTKEKQSSEEEEKETRGVQ---KRRGGSTVP 296
Score = 35.4 bits (80), Expect = 0.16
Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 9/46 (19%)
Query: 458 GHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGH 503
GH H Q+ GH H+ +D HGH H HGHGH
Sbjct: 30 GHDDLHDDLQEDFHGHSHRHSHED---------FHHGHSHAHGHGH 66
Score = 32.0 bits (71), Expect = 1.8
Identities = 13/27 (48%), Positives = 14/27 (51%), Gaps = 3/27 (11%)
Query: 442 GHGHKHERDQGHGHQRGHGLGHGHEQQ 468
GHGH H H H RG HGH +Q
Sbjct: 243 GHGHSHGHGHAHSHTRG---SHGHGRQ 266
>gi|4503113 cystatin M precursor [Homo sapiens]
Length = 149
Score = 55.5 bits (132), Expect = 2e-07
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 7/108 (6%)
Query: 260 PTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFI 319
P + VG RD+ + P++++ + N +N+ +YF+ ++ KA+ Q+VAG KYF+
Sbjct: 30 PQERMVGELRDLSPDDPQVQKAAQAAVASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYFL 89
Query: 320 DFVARETTCSKE----SNEELTESCETKKLGQ--SLDCNAEVYVVPWE 361
T C K + +LT +C Q L C+ EV VVPW+
Sbjct: 90 TMEMGSTDCRKTRVTGDHVDLT-TCPLAAGAQQEKLRCDFEVLVVPWQ 136
Score = 32.3 bits (72), Expect = 1.4
Identities = 15/66 (22%), Positives = 32/66 (48%)
Query: 143 LGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLNEVKRAQRQVVAGLNFRITYSIV 202
+G + +S P ++ + + +N + F + +AQ Q+VAG+ + +T +
Sbjct: 35 VGELRDLSPDDPQVQKAAQAAVASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMG 94
Query: 203 QTNCSK 208
T+C K
Sbjct: 95 STDCRK 100
>gi|4503107 cystatin C precursor [Homo sapiens]
Length = 146
Score = 52.8 bits (125), Expect = 1e-06
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 7/111 (6%)
Query: 252 PGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQV 311
PGK PP VG P D + L + + N +N ++ + V +AR Q+
Sbjct: 29 PGK----PPR--LVGGPMDASVEEEGVRRALDFAVGEYNKASNDMYHSRALQVVRARKQI 82
Query: 312 VAGKKYFIDFVARETTCSK-ESNEELTESCETKKLGQSLDCNAEVYVVPWE 361
VAG YF+D TTC+K + N + + L + C+ ++Y VPW+
Sbjct: 83 VAGVNYFLDVELGRTTCTKTQPNLDNCPFHDQPHLKRKAFCSFQIYAVPWQ 133
Score = 30.4 bits (67), Expect = 5.3
Identities = 14/41 (34%), Positives = 26/41 (63%), Gaps = 3/41 (7%)
Query: 168 NNNTQHSSLFMLNEVKRAQRQVVAGLNFRITYSIVQTNCSK 208
+N+ HS +V RA++Q+VAG+N+ + + +T C+K
Sbjct: 64 SNDMYHSRAL---QVVRARKQIVAGVNYFLDVELGRTTCTK 101
>gi|4503105 cystatin SA precursor [Homo sapiens]
Length = 141
Score = 52.0 bits (123), Expect = 2e-06
Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 1/108 (0%)
Query: 258 QPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKY 317
Q +I G D N ++ L I++ N +Y ++ V +AR Q+V G Y
Sbjct: 24 QEEDRIIEGGIYDADLNDERVQRALHFVISEYNKATEDEYYRRLLRVLRAREQIVGGVNY 83
Query: 318 FIDFVARETTCSK-ESNEELTESCETKKLGQSLDCNAEVYVVPWEKKI 364
F D T C+K + N + E +L + C+ ++Y VPWE ++
Sbjct: 84 FFDIEVGRTICTKSQPNLDTCAFHEQPELQKKQLCSFQIYEVPWEDRM 131
>gi|222080086 zinc transporter like 2 [Homo sapiens]
Length = 376
Score = 50.1 bits (118), Expect = 6e-06
Identities = 24/55 (43%), Positives = 27/55 (49%), Gaps = 6/55 (10%)
Query: 452 GHGHQRGHGLGHGHEQQHGL---GHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGH 503
GHGH G G GH H +G HGH +D H+ H H H H HGHGH
Sbjct: 163 GHGHSHGSGHGHSHSLFNGALDQAHGH---VDHCHSHEVKHGAAHSHDHAHGHGH 214
Score = 41.6 bits (96), Expect = 0.002
Identities = 20/49 (40%), Positives = 22/49 (44%), Gaps = 12/49 (24%)
Query: 439 HNLGHGHKHER-----DQGHGH-------QRGHGLGHGHEQQHGLGHGH 475
H GHGH H DQ HGH + HG H H+ HG GH H
Sbjct: 168 HGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFH 216
Score = 35.8 bits (81), Expect = 0.13
Identities = 19/59 (32%), Positives = 21/59 (35%), Gaps = 10/59 (16%)
Query: 421 KEQGHTRRHDWGHEK----------QRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQH 469
K GH H GH Q ++ H H HE G H H GHGH H
Sbjct: 160 KHGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSH 218
>gi|40255009 zinc transporter like 2 [Homo sapiens]
Length = 376
Score = 50.1 bits (118), Expect = 6e-06
Identities = 24/55 (43%), Positives = 27/55 (49%), Gaps = 6/55 (10%)
Query: 452 GHGHQRGHGLGHGHEQQHGL---GHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGH 503
GHGH G G GH H +G HGH +D H+ H H H H HGHGH
Sbjct: 163 GHGHSHGSGHGHSHSLFNGALDQAHGH---VDHCHSHEVKHGAAHSHDHAHGHGH 214
Score = 41.6 bits (96), Expect = 0.002
Identities = 20/49 (40%), Positives = 22/49 (44%), Gaps = 12/49 (24%)
Query: 439 HNLGHGHKHER-----DQGHGH-------QRGHGLGHGHEQQHGLGHGH 475
H GHGH H DQ HGH + HG H H+ HG GH H
Sbjct: 168 HGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFH 216
Score = 35.8 bits (81), Expect = 0.13
Identities = 19/59 (32%), Positives = 21/59 (35%), Gaps = 10/59 (16%)
Query: 421 KEQGHTRRHDWGHEK----------QRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQH 469
K GH H GH Q ++ H H HE G H H GHGH H
Sbjct: 160 KHGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSH 218
>gi|19882259 cystatin-like 1 precursor [Homo sapiens]
Length = 145
Score = 47.8 bits (112), Expect = 3e-05
Identities = 20/83 (24%), Positives = 42/83 (50%)
Query: 278 LEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELT 337
+ TL I N +N T+ +++ + ++++Q+ G +Y + T C + +
Sbjct: 41 MNSTLNFFIQSYNNASNDTYLYRVQRLIRSQMQLTTGVEYIVTVKIGWTKCKRNDTSNSS 100
Query: 338 ESCETKKLGQSLDCNAEVYVVPW 360
++KKL +SL C + +Y +PW
Sbjct: 101 CPLQSKKLRKSLICESLIYTMPW 123
Score = 32.0 bits (71), Expect = 1.8
Identities = 14/56 (25%), Positives = 29/56 (51%)
Query: 155 DLEPILRHGIQYFNNNTQHSSLFMLNEVKRAQRQVVAGLNFRITYSIVQTNCSKEN 210
++ L IQ +NN + + L+ + + R+Q Q+ G+ + +T I T C + +
Sbjct: 40 NMNSTLNFFIQSYNNASNDTYLYRVQRLIRSQMQLTTGVEYIVTVKIGWTKCKRND 95
>gi|19882251 cystatin SN precursor [Homo sapiens]
Length = 141
Score = 46.2 bits (108), Expect = 9e-05
Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
Query: 274 NSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFIDFVARETTCSK-ES 332
N ++ L I++ N +Y + V +AR Q V G YF D T C+K +
Sbjct: 40 NDEWVQRALHFAISEYNKATKDDYYRRPLRVLRARQQTVGGVNYFFDVEVGRTICTKSQP 99
Query: 333 NEELTESCETKKLGQSLDCNAEVYVVPWEKK 363
N + E +L + C+ E+Y VPWE +
Sbjct: 100 NLDTCAFHEQPELQKKQLCSFEIYEVPWENR 130
>gi|4503109 cystatin S precursor [Homo sapiens]
Length = 141
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 1/104 (0%)
Query: 262 KICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFIDF 321
+I G D N ++ L I++ N +Y + V +AR Q G YF D
Sbjct: 28 RIIPGGIYDADLNDEWVQRALHFAISEYNKATEDEYYRRPLQVLRAREQTFGGVNYFFDV 87
Query: 322 VARETTCSK-ESNEELTESCETKKLGQSLDCNAEVYVVPWEKKI 364
T C+K + N + E +L + C+ E+Y VPWE ++
Sbjct: 88 EVGRTICTKSQPNLDTCAFHEQPELQKKQLCSFEIYEVPWEDRM 131
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 45.4 bits (106), Expect = 2e-04
Identities = 46/156 (29%), Positives = 61/156 (39%), Gaps = 14/156 (8%)
Query: 400 TTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGH---- 455
++VS S ++D ER SG + W E+ R + G HE GHGH
Sbjct: 1916 SSVSQDSDSQGHSEDSERWSGSASRNHLGSAW--EQSRDGSRHPGSHHEDRAGHGHSADS 1973
Query: 456 QRGHGLGHGHEQQHG-LGHGHKFKLDDDLEHQGG-HVLDHGHKHKH-GHGHGKHKNKGKK 512
R G H G H+ E G H L +H G GHG+ + +
Sbjct: 1974 SRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRD 2033
Query: 513 NGKHNGWKTEHLASS---SEDSTTPSAQTQEKTEGP 545
+G H G+ + S SEDS T S Q K GP
Sbjct: 2034 SG-HRGYSGSQASDSEGHSEDSDTQSVSAQGKA-GP 2067
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/136 (25%), Positives = 47/136 (34%), Gaps = 3/136 (2%)
Query: 413 QDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHE-RDQGHGHQRGHGLGH--GHEQQH 469
+ E G+ T H KQ + + H E +D HGH G H +Q
Sbjct: 2422 EQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQL 2481
Query: 470 GLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSE 529
GH QG HGH ++ +G + H ASS
Sbjct: 2482 VDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRA 2541
Query: 530 DSTTPSAQTQEKTEGP 545
DS+ S Q ++EGP
Sbjct: 2542 DSSGHSQVGQGQSEGP 2557
Score = 40.0 bits (92), Expect = 0.007
Identities = 34/136 (25%), Positives = 49/136 (36%), Gaps = 5/136 (3%)
Query: 413 QDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERD---QGH-GHQRGHGLGHGHEQQ 468
+ E G+ + T R H +Q + + H E + H G +RG G HEQ
Sbjct: 1125 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQS 1184
Query: 469 HGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSS 528
GH QG HG K+K +G + H A+S
Sbjct: 1185 VDRS-GHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASW 1243
Query: 529 EDSTTPSAQTQEKTEG 544
DS+ S QE++ G
Sbjct: 1244 ADSSRHSQVGQEQSSG 1259
Score = 39.3 bits (90), Expect = 0.011
Identities = 32/138 (23%), Positives = 51/138 (36%), Gaps = 20/138 (14%)
Query: 397 KEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQ 456
++ ++VS S ++D ER SG +R H ++Q +H H H D+
Sbjct: 941 RQGSSVSQDSDSEGHSEDSERWSGSA---SRNHRGSAQEQSRHGSRHPRSHHEDRA---- 993
Query: 457 RGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKH---GHGHGKHKNKGKKN 513
GHG +Q G H E G H+ G HG + +
Sbjct: 994 -GHGHSADSSRQSGTPHA---------ETSSGGQAASSHEQARSSPGERHGSRHQQSADS 1043
Query: 514 GKHNGWKTEHLASSSEDS 531
+H+G +S+ DS
Sbjct: 1044 SRHSGIPRRQASSAVRDS 1061
Score = 39.3 bits (90), Expect = 0.011
Identities = 29/136 (21%), Positives = 45/136 (33%), Gaps = 3/136 (2%)
Query: 413 QDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERD---QGHGHQRGHGLGHGHEQQH 469
+ E G+ + T R H +Q + + H E +GH G H +Q
Sbjct: 3394 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQS 3453
Query: 470 GLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSE 529
GH QG G ++ +G + W H AS+
Sbjct: 3454 VDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQA 3513
Query: 530 DSTTPSAQTQEKTEGP 545
DS+ S Q ++ GP
Sbjct: 3514 DSSRHSQSGQGQSAGP 3529
Score = 37.7 bits (86), Expect = 0.033
Identities = 36/142 (25%), Positives = 50/142 (35%), Gaps = 12/142 (8%)
Query: 414 DEERDSGKEQGHTRRHDWG---HEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHG 470
D R SG + H HE+ R + G H Q R G+GH
Sbjct: 1324 DSSRQSGTHHTESSSHGQAVSSHEQARS-SPGERHGSRHQQSADSSRHSGIGHRQASSAV 1382
Query: 471 LGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGH-GKHKNKGK-----KNGKHNGWKTEHL 524
GH+ + + GH D + HG G H+ K ++G+ +G L
Sbjct: 1383 RDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFL 1442
Query: 525 --ASSSEDSTTPSAQTQEKTEG 544
SS E S + QT T G
Sbjct: 1443 YQVSSHEQSESTHGQTAPSTGG 1464
Score = 36.2 bits (82), Expect = 0.096
Identities = 35/137 (25%), Positives = 47/137 (34%), Gaps = 7/137 (5%)
Query: 415 EERDS--GKEQGHTRRHDWGHEKQRKHNLGHGHKHERD---QGH-GHQRGHGLGHGHEQQ 468
E+ DS G+ T H +Q + + H E +GH G RG G HEQ
Sbjct: 476 EQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQS 535
Query: 469 HGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSS 528
GH QG HG + +G + H ASS
Sbjct: 536 VNRS-GHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQ 594
Query: 529 EDSTTPSAQTQEKTEGP 545
DS+ S Q ++ GP
Sbjct: 595 ADSSRHSQVGQGQSSGP 611
Score = 36.2 bits (82), Expect = 0.096
Identities = 31/141 (21%), Positives = 49/141 (34%), Gaps = 14/141 (9%)
Query: 418 DSGKEQG--HTRRHDWGH----EKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGL 471
DS ++ G HT+ G +Q + + G H Q R G+GHG
Sbjct: 2621 DSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 2680
Query: 472 GHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGH-GKHKNKGKKNGKHNGWKTE-------H 523
GH+ GH D + HG G H+ +++ + +T +
Sbjct: 2681 DSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLY 2740
Query: 524 LASSSEDSTTPSAQTQEKTEG 544
S+ E S + T T G
Sbjct: 2741 QVSTHEQSESSHGWTGPSTRG 2761
Score = 36.2 bits (82), Expect = 0.096
Identities = 31/141 (21%), Positives = 49/141 (34%), Gaps = 14/141 (9%)
Query: 418 DSGKEQG--HTRRHDWGH----EKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGL 471
DS ++ G HT+ G +Q + + G H Q R G+GHG
Sbjct: 2945 DSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 3004
Query: 472 GHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGH-GKHKNKGKKNGKHNGWKTE-------H 523
GH+ GH D + HG G H+ +++ + +T +
Sbjct: 3005 DSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLY 3064
Query: 524 LASSSEDSTTPSAQTQEKTEG 544
S+ E S + T T G
Sbjct: 3065 QVSTHEQSESSHGWTGPSTRG 3085
Score = 35.4 bits (80), Expect = 0.16
Identities = 30/143 (20%), Positives = 49/143 (34%), Gaps = 23/143 (16%)
Query: 410 APAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHE--RDQGH----GHQRGHGLGH 463
A + ++ R S E+ H H + R +GHG RD GH G Q GH
Sbjct: 2640 ASSHEQARSSAGER-HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGH 2698
Query: 464 GHEQQ------HGLGHGHKFKLDDDLEHQGGHVLDHG----------HKHKHGHGHGKHK 507
+ HG H+ + + G H + + HG
Sbjct: 2699 SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS 2758
Query: 508 NKGKKNGKHNGWKTEHLASSSED 530
+G++ +H + S+S+D
Sbjct: 2759 TRGRQGSRHEQAQDSSRHSASQD 2781
Score = 34.7 bits (78), Expect = 0.28
Identities = 30/126 (23%), Positives = 41/126 (32%), Gaps = 16/126 (12%)
Query: 422 EQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGL-------GHGHEQQHG---L 471
++ TR+ Q + + GH ER G + HG G H + H
Sbjct: 285 QESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRA 344
Query: 472 GHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDS 531
HGH D Q G H G H+ G+ +G + A SS S
Sbjct: 345 SHGH----SADSSRQSG--TRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHS 398
Query: 532 TTPSAQ 537
T Q
Sbjct: 399 ATGRGQ 404
Score = 33.9 bits (76), Expect = 0.48
Identities = 32/140 (22%), Positives = 54/140 (38%), Gaps = 12/140 (8%)
Query: 418 DSGKEQG--HTRRHDWGH----EKQRKHNLG--HGHKHERDQGHGHQRGHGLGHGHEQQH 469
DS ++ G HT+ G +Q + + G HG +H+ Q R G GHG
Sbjct: 675 DSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQL-QSADSSRHSGTGHGQASSA 733
Query: 470 GLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGH-GKHKNKGKKNGKHNGWKTEHLASS- 527
GH+ GH D + GHG G H+ +++ + + + S
Sbjct: 734 VRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSF 793
Query: 528 -SEDSTTPSAQTQEKTEGPT 546
+ ST +++ GP+
Sbjct: 794 LYQVSTHKQSESSHGWTGPS 813
Score = 33.9 bits (76), Expect = 0.48
Identities = 32/132 (24%), Positives = 42/132 (31%), Gaps = 26/132 (19%)
Query: 412 AQDEERDSGKEQGHTRRH-DWGHEKQRKHNLGHGHKHERDQGHG-HQRGHGLGHGHEQQH 469
++D R SG H D Q G + R QG Q GH + +
Sbjct: 902 SRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSER 961
Query: 470 GLG---HGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLAS 526
G H+ + H H H H+ + GHGH A
Sbjct: 962 WSGSASRNHRGSAQEQSRHGSRHPRSH-HEDRAGHGHS--------------------AD 1000
Query: 527 SSEDSTTPSAQT 538
SS S TP A+T
Sbjct: 1001 SSRQSGTPHAET 1012
Score = 33.5 bits (75), Expect = 0.62
Identities = 31/154 (20%), Positives = 50/154 (32%), Gaps = 7/154 (4%)
Query: 387 PFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHK 446
P + SR + + + VS S ++D ER SG +R H +Q + H
Sbjct: 283 PLQESRTRK-RRGSRVSQDRDSEGHSEDSERHSGSA---SRNHHGSAWEQSRDGSRHPRS 338
Query: 447 HERDQ-GHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGK 505
H+ D+ HGH G G + G HG H+ +
Sbjct: 339 HDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGE--RHGSGHQQSADSSR 396
Query: 506 HKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQ 539
H G+ H SS ++ ++
Sbjct: 397 HSATGRGQASSAVSDRGHRGSSGSQASDSEGHSE 430
Score = 33.5 bits (75), Expect = 0.62
Identities = 32/145 (22%), Positives = 44/145 (30%), Gaps = 18/145 (12%)
Query: 410 APAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHE--RDQGH----GHQRGHGLGH 463
A + ++ R S E+ H H + R +GHG RD GH G Q GH
Sbjct: 2964 ASSHEQARSSAGER-HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGH 3022
Query: 464 GHEQQ------HGLGHGHKFKLDDDLEHQGGHVLDHG-----HKHKHGHGHGKHKNKGKK 512
+ HG H+ + + G H H H G
Sbjct: 3023 SEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS 3082
Query: 513 NGKHNGWKTEHLASSSEDSTTPSAQ 537
G + E SS S + Q
Sbjct: 3083 TRGRQGSRHEQAQDSSRHSASQYGQ 3107
Score = 32.0 bits (71), Expect = 1.8
Identities = 48/202 (23%), Positives = 66/202 (32%), Gaps = 39/202 (19%)
Query: 381 RPPGFSPFRSSRI---GEIKEETTVSPPHTSMAPAQDEERDSGKE--QGHTRRHDWGHEK 435
RP G S + S E E + S AQ++ RD + H R GH
Sbjct: 2237 RPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSA 2296
Query: 436 QRKHNLGHGHKHERDQGH---GHQRGH---GLGHG-HEQQ-------HGLGHGHKFKLDD 481
+ G H G H++ G HG H QQ G+GHG
Sbjct: 2297 ESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVR 2356
Query: 482 DLEHQG----------GHVLD--------HGHKHKHGHGHGKHKNKGKKNGKH-NGWKTE 522
D H+G GH D HG H H + +G+ G+
Sbjct: 2357 DSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSH-QESTRGRSAGRSGRSGSFL 2415
Query: 523 HLASSSEDSTTPSAQTQEKTEG 544
+ S+ E S + +T T G
Sbjct: 2416 YQVSTHEQSESAHGRTGTSTGG 2437
Score = 31.6 bits (70), Expect = 2.4
Identities = 41/162 (25%), Positives = 54/162 (33%), Gaps = 8/162 (4%)
Query: 384 GFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGH 443
G S RS R G + VS S + +G QG RH+ + R
Sbjct: 3698 GRSAGRSGRSGSFLYQ--VSTHEQSESAHGRAGPSTGGRQGS--RHEQARDSSRHSASQE 3753
Query: 444 GHKHERDQGH-GHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHG 502
G R GH G +RG G HEQ GH QG HG
Sbjct: 3754 GQDTIR--GHPGSRRGGRQGSYHEQSVDRS-GHSGSHHSHTTSQGRSDASHGQSGSRSAS 3810
Query: 503 HGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEG 544
+ +G + H AS+ DS+ S Q ++ G
Sbjct: 3811 RETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAG 3852
Score = 31.2 bits (69), Expect = 3.1
Identities = 33/137 (24%), Positives = 50/137 (36%), Gaps = 18/137 (13%)
Query: 410 APAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHE--RDQGHGHQRGHGLGHGHEQ 467
A + ++ R S E+ +R + R GHG RD GH RG G +
Sbjct: 694 ASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGH---RG---SSGSQA 747
Query: 468 QHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGW----KTEH 523
GH D D + GH GH H+ H G+++ + + T
Sbjct: 748 TDSEGHSE----DSDTQSVSGHG-QAGH-HQQSHQESARDRSGERSRRSGSFLYQVSTHK 801
Query: 524 LASSSEDSTTPSAQTQE 540
+ SS T PS ++
Sbjct: 802 QSESSHGWTGPSTGVRQ 818
Score = 30.8 bits (68), Expect = 4.0
Identities = 41/181 (22%), Positives = 62/181 (34%), Gaps = 29/181 (16%)
Query: 395 EIKEETTVSPPHTSMAPAQDEERDSGKE--QGHTRRHDWGHEKQRKHNLGHGHKHERDQG 452
E E + S AQ++ RD + H R GH + G H G
Sbjct: 3550 EDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGG 3609
Query: 453 H---GHQRGH---GLGHG-HEQQ-------HGLGHGHKFKLDDDLEHQG----------G 488
H++ G HG H QQ G+GHG D H+G G
Sbjct: 3610 QAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEG 3669
Query: 489 HVLDHGHKHKHGHGH-GKHKNKGKKN--GKHNGWKTEHLASSSEDSTTPSAQTQEKTEGP 545
H D + HG G H+ +++ G+ G + + ST +++ GP
Sbjct: 3670 HSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGP 3729
Query: 546 T 546
+
Sbjct: 3730 S 3730
Score = 30.8 bits (68), Expect = 4.0
Identities = 33/145 (22%), Positives = 44/145 (30%), Gaps = 18/145 (12%)
Query: 410 APAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHE--RDQGH----GHQRGHGLGH 463
A + ++ R S E+ H H + R +GHG RD GH G Q GH
Sbjct: 3612 ASSHEQARSSAGER-HGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGH 3670
Query: 464 GHEQQ------HGLGHGHKFKLDDDLE-HQGGHVLDHG----HKHKHGHGHGKHKNKGKK 512
+ HG H+ + G G H H G
Sbjct: 3671 SEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPS 3730
Query: 513 NGKHNGWKTEHLASSSEDSTTPSAQ 537
G G + E SS S + Q
Sbjct: 3731 TGGRQGSRHEQARDSSRHSASQEGQ 3755
Score = 30.0 bits (66), Expect = 6.9
Identities = 30/134 (22%), Positives = 40/134 (29%), Gaps = 7/134 (5%)
Query: 419 SGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQ-GHGHQRGH------GLGHGHEQQHGL 471
S G T G ++ R +H Q G RGH G H +Q
Sbjct: 1775 SESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVD 1834
Query: 472 GHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDS 531
GH Q + G K +G + H ASS DS
Sbjct: 1835 SSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADS 1894
Query: 532 TTPSAQTQEKTEGP 545
+ S Q ++ GP
Sbjct: 1895 SRHSQVGQGQSSGP 1908
Score = 30.0 bits (66), Expect = 6.9
Identities = 33/141 (23%), Positives = 45/141 (31%), Gaps = 23/141 (16%)
Query: 419 SGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQ-GHGHQRGH-GLGHGHEQQHGLGHGHK 476
S G T G + R +H Q G RGH G G Q G+ H+
Sbjct: 2748 SESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQ----GYHHE 2803
Query: 477 FKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKN-------------GKHNGWKTEH 523
+D H G H H H G G ++ G + H
Sbjct: 2804 HSVDSS-GHSGSH---HSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHH 2859
Query: 524 LASSSEDSTTPSAQTQEKTEG 544
AS+ D + S Q ++EG
Sbjct: 2860 EASTHADISRHSQAVQGQSEG 2880
Score = 29.6 bits (65), Expect = 9.0
Identities = 24/115 (20%), Positives = 36/115 (31%), Gaps = 3/115 (2%)
Query: 433 HEKQRKHNLGHGHKHERD---QGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGH 489
H +Q + N H + +GH G H +Q GH QG
Sbjct: 821 HHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRS 880
Query: 490 VLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEG 544
G + ++G + H ASS D + S Q ++EG
Sbjct: 881 DASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEG 935
Score = 29.6 bits (65), Expect = 9.0
Identities = 31/137 (22%), Positives = 45/137 (32%), Gaps = 5/137 (3%)
Query: 413 QDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERD---QGH-GHQRGHGLGHGHEQQ 468
+ E G+ T H Q + + H E +GH G RG G H++Q
Sbjct: 2098 EQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQG-SHQEQ 2156
Query: 469 HGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSS 528
GH QG G + + +G + H ASS
Sbjct: 2157 SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSW 2216
Query: 529 EDSTTPSAQTQEKTEGP 545
DS+ S Q ++ GP
Sbjct: 2217 ADSSRHSLVGQGQSSGP 2233
>gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
Length = 525
Score = 45.4 bits (106), Expect = 2e-04
Identities = 92/427 (21%), Positives = 140/427 (32%), Gaps = 76/427 (17%)
Query: 135 VVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLNEVKRAQRQVVAGLN 194
++T QY C V P T +EP + N + LF L + A V
Sbjct: 10 LITLQYSC--AVSP--TDCSAVEPEAEKALDLINKRRRDGYLFQLLRIADAHLDRVENTT 65
Query: 195 -FRITYSIVQTNCSKENFLFLT----PDCKSLWNGDTGEC----TDNAYIDIQLRIASFS 245
+ + + +++CS + + PD + G+C T +++ LR+ F
Sbjct: 66 VYYLVLDVQESDCSVLSRKYWNDCEPPDSRRPSEIVIGQCKVIATRHSHESQDLRVIDF- 124
Query: 246 QNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTH------TITKLNAENNATFYF 299
NC + +D P E+T + + K EN+ F
Sbjct: 125 -NC--------TTSSVSSALANTKDSPVLIDFFEDTERYRKQANKALEKYKEENDDFASF 175
Query: 300 KIDNVKK-ARVQVVAGKKYFIDFVARETTCSKES---NEELTESCETKKLGQSLDCNAEV 355
++D +++ ARV+ G YF+DF R C + + + C D +V
Sbjct: 176 RVDRIERVARVRGGEGTGYFVDFSVRN--CPRHHFPRHPNVFGFCRA-------DLFYDV 226
Query: 356 YVVPWEKKIYPTVNCQ---PLGMISLMKRPPGFS-PFRSSRIGEIKEETTVSP------- 404
+ E +NC+ P ++ PP PF G + TT P
Sbjct: 227 EALDLESPKNLVINCEVFDPQEHENINGVPPHLGHPFHWG--GHERSSTTKPPFKPHGSR 284
Query: 405 -------PHTSMAPAQDEERDSGK----EQGHTRRHDWGHEKQRKHNLGHG----HKHER 449
PH P +ERD QG + G H H
Sbjct: 285 DHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNN 344
Query: 450 DQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNK 509
+ H H H HEQ HGH EH HGH H HG H +
Sbjct: 345 NSSDLHPHKH---HSHEQHP---HGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHG 398
Query: 510 GKKNGKH 516
+G H
Sbjct: 399 HHPHGHH 405
Score = 43.9 bits (102), Expect = 5e-04
Identities = 30/111 (27%), Positives = 49/111 (44%), Gaps = 6/111 (5%)
Query: 9 LCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRITEA-TKTVG 67
+ + LL++L DC+ + + AL N + + F L RI +A V
Sbjct: 5 IAALLLITLQYSCAVSPTDCSAVE--PEAEKALDLINKRRRDGYLFQLLRIADAHLDRVE 62
Query: 68 SDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDA---AKAATGECTATVGKRS 115
+ T Y +++E DC V S K W DCE D+ ++ G+C + S
Sbjct: 63 NTTVYYLVLDVQESDCSVLSRKYWNDCEPPDSRRPSEIVIGQCKVIATRHS 113
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 44.3 bits (103), Expect = 4e-04
Identities = 34/141 (24%), Positives = 58/141 (41%), Gaps = 16/141 (11%)
Query: 413 QDEERDSG---KEQGHTRRHDWGH------EKQRKHNLGHGHKHERDQGHGHQRGHGLGH 463
QDEER+ G K +G R G E+ +K + + ER+QGH +R +
Sbjct: 670 QDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEE 729
Query: 464 GHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEH 523
G E++HG G + +++ E + G + G G + K+ G+ +
Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKE-------GEGKEEGEGEEVEGEREKEEGERKKEERAG 782
Query: 524 LASSSEDSTTPSAQTQEKTEG 544
E+ +E+TEG
Sbjct: 783 KEEKGEEEGDQGEGEEEETEG 803
Score = 39.3 bits (90), Expect = 0.011
Identities = 29/126 (23%), Positives = 55/126 (43%), Gaps = 17/126 (13%)
Query: 416 ERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGH 475
E + G+ +G +W E++ G G E +G G + G G G E++ G G G
Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEE----GEGEGEEEGEGEG-EEGEGEG---EEEEGEGEGE 991
Query: 476 KFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPS 535
+ + +++ E + G + G G G+ + +G+ G+ G + E E+
Sbjct: 992 EEEGEEEGE-------EEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE--GEGEEEEGEEE 1042
Query: 536 AQTQEK 541
+ +EK
Sbjct: 1043 GEEREK 1048
Score = 33.1 bits (74), Expect = 0.81
Identities = 34/152 (22%), Positives = 62/152 (40%), Gaps = 19/152 (12%)
Query: 394 GEIKEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKH-ERDQG 452
GE +EE ++EE + +E+G + + G E G G + E +G
Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE-------GEGEEEGEEGEG 876
Query: 453 HGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKK 512
G + G G G E+ G G + + + + E +G + + G GK + +G++
Sbjct: 877 EGEEE-EGEGEGEEEGEGEGEEEEGEGEGEEEGEG--------EGEEEEGEGKGEEEGEE 927
Query: 513 NGKHNGWKTEHLASSSEDSTTPSAQTQEKTEG 544
G+ G + E ED + + + EG
Sbjct: 928 -GEGEG-EEEEGEGEGEDGEGEGEEEEGEWEG 957
Score = 31.2 bits (69), Expect = 3.1
Identities = 21/102 (20%), Positives = 41/102 (40%), Gaps = 6/102 (5%)
Query: 413 QDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHE-----RDQGHGHQRGHGLGHGHEQ 467
++E G+E+G + E + + G G + E ++G G + G G G E+
Sbjct: 959 EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018
Query: 468 QHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNK 509
G + + + E + G + + K G G +N+
Sbjct: 1019 GEVEGEVEGEEGEGEGEEEEGEE-EGEEREKEGEGEENRRNR 1059
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 44.3 bits (103), Expect = 4e-04
Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 18/123 (14%)
Query: 413 QDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLG 472
++EE + +E+ T ++GH+ R + GHG + + D GH HG H H+
Sbjct: 194 EEEEEEEEEEEAST---EYGHQAHR--HRGHGSEEDEDVSDGHHH-HGPSHRHQ------ 241
Query: 473 HGHKFKLDDDLEHQGGH-----VLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASS 527
GH+ DDD + +++ H+ GHG +++ +G H+ + S
Sbjct: 242 -GHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSH 300
Query: 528 SED 530
ED
Sbjct: 301 EED 303
Score = 38.1 bits (87), Expect = 0.025
Identities = 33/153 (21%), Positives = 53/153 (34%), Gaps = 17/153 (11%)
Query: 406 HTSMAPAQDEERDSGKEQGH--TRRHDWGHEKQR-------KHNLGHGHKHERDQGHGHQ 456
H + ++EE + + GH GH+ K + H H H + +
Sbjct: 370 HHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEE 429
Query: 457 RGHGLGH---GHEQQHG---LGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKG 510
LGH H Q H GHG + + + H GH + H + K K
Sbjct: 430 VSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKE 489
Query: 511 KKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTE 543
+ G H + + + E T ++ QE E
Sbjct: 490 EDPGSHE--EDDESSEQGEKGTHHGSRDQEDEE 520
Score = 35.4 bits (80), Expect = 0.16
Identities = 33/173 (19%), Positives = 58/173 (33%), Gaps = 45/173 (26%)
Query: 413 QDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHE------------------------ 448
++EE ++ E GH GH + ++ GH H
Sbjct: 199 EEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDD 258
Query: 449 -------------RDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGH 495
R QGHG + + GH + H H+ +DD + ++GH
Sbjct: 259 DDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDP-SHRHRSHEEDDNDDDDVST-EYGH 316
Query: 496 KHKHGHGHGKHKNKGKK--NGKHNGWKTEHLASSSED-STTPSAQTQEKTEGP 545
+ H H H+ + + +G+H+ +H D T+ +GP
Sbjct: 317 Q---AHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTERWHQGP 366
Score = 35.0 bits (79), Expect = 0.21
Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 23/102 (22%)
Query: 394 GEIKEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGH 453
G IKE + P HT + K++ H R+ D EK+++ + G HE D
Sbjct: 456 GSIKEMSHHPPGHTVV-----------KDRSHLRKDDSEEEKEKEEDPG---SHEEDDES 501
Query: 454 GHQRGHGLGHG---------HEQQHGLGHGHKFKLDDDLEHQ 486
Q G HG E+ HGL + + ++D E +
Sbjct: 502 SEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEE 543
>gi|59938776 cAMP responsive element binding protein 5 isoform delta
[Homo sapiens]
Length = 369
Score = 43.5 bits (101), Expect = 6e-04
Identities = 43/193 (22%), Positives = 63/193 (32%), Gaps = 28/193 (14%)
Query: 357 VVPWEKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEE 416
++P E+++ +VN +GM P SP E K + H A +
Sbjct: 56 LMPMERQM--SVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNM 113
Query: 417 RDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERD-----QGHGHQRGHGLGHGHEQQHGL 471
GH + Q H+ H H H+ + HQ H H H Q H
Sbjct: 114 NT----MGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPH-- 167
Query: 472 GHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDS 531
HQ H H H H H H H H H G + + ++ +
Sbjct: 168 -------------HQQNH--PHHHSHSHLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQ 212
Query: 532 TTPSAQTQEKTEG 544
T + Q + T G
Sbjct: 213 PTQTIQPPQPTGG 225
>gi|59938774 cAMP responsive element binding protein 5 isoform beta
[Homo sapiens]
Length = 501
Score = 43.5 bits (101), Expect = 6e-04
Identities = 43/193 (22%), Positives = 63/193 (32%), Gaps = 28/193 (14%)
Query: 357 VVPWEKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEE 416
++P E+++ +VN +GM P SP E K + H A +
Sbjct: 188 LMPMERQM--SVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNM 245
Query: 417 RDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERD-----QGHGHQRGHGLGHGHEQQHGL 471
GH + Q H+ H H H+ + HQ H H H Q H
Sbjct: 246 NT----MGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPH-- 299
Query: 472 GHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDS 531
HQ H H H H H H H H H G + + ++ +
Sbjct: 300 -------------HQQNH--PHHHSHSHLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQ 344
Query: 532 TTPSAQTQEKTEG 544
T + Q + T G
Sbjct: 345 PTQTIQPPQPTGG 357
>gi|59938772 cAMP responsive element binding protein 5 isoform gamma
[Homo sapiens]
Length = 475
Score = 43.5 bits (101), Expect = 6e-04
Identities = 43/193 (22%), Positives = 63/193 (32%), Gaps = 28/193 (14%)
Query: 357 VVPWEKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEE 416
++P E+++ +VN +GM P SP E K + H A +
Sbjct: 162 LMPMERQM--SVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNM 219
Query: 417 RDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERD-----QGHGHQRGHGLGHGHEQQHGL 471
GH + Q H+ H H H+ + HQ H H H Q H
Sbjct: 220 NT----MGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPH-- 273
Query: 472 GHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDS 531
HQ H H H H H H H H H G + + ++ +
Sbjct: 274 -------------HQQNH--PHHHSHSHLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQ 318
Query: 532 TTPSAQTQEKTEG 544
T + Q + T G
Sbjct: 319 PTQTIQPPQPTGG 331
>gi|59938770 cAMP responsive element binding protein 5 isoform alpha
[Homo sapiens]
Length = 508
Score = 43.5 bits (101), Expect = 6e-04
Identities = 43/193 (22%), Positives = 63/193 (32%), Gaps = 28/193 (14%)
Query: 357 VVPWEKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEE 416
++P E+++ +VN +GM P SP E K + H A +
Sbjct: 195 LMPMERQM--SVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNM 252
Query: 417 RDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERD-----QGHGHQRGHGLGHGHEQQHGL 471
GH + Q H+ H H H+ + HQ H H H Q H
Sbjct: 253 NT----MGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPH-- 306
Query: 472 GHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDS 531
HQ H H H H H H H H H G + + ++ +
Sbjct: 307 -------------HQQNH--PHHHSHSHLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQ 351
Query: 532 TTPSAQTQEKTEG 544
T + Q + T G
Sbjct: 352 PTQTIQPPQPTGG 364
>gi|156523970 alpha-2-HS-glycoprotein [Homo sapiens]
Length = 367
Score = 43.1 bits (100), Expect = 8e-04
Identities = 43/189 (22%), Positives = 76/189 (40%), Gaps = 16/189 (8%)
Query: 154 PDLEPILRHGIQYFNNNTQHSSLFMLNEVKRAQ--RQVVAGLNFRITYSIVQTNCSKENF 211
P+ E I Y N N LN++ + Q +G F I ++T C +
Sbjct: 35 PETEEAALVAIDYINQNLPWGYKHTLNQIDEVKVWPQQPSGELFEIEIDTLETTC---HV 91
Query: 212 LFLTPDCKSLW-----NGDTGECTDNAYIDIQLRIASFSQNCDIYPGKDFVQPPTKICVG 266
L TP + + G+C D + + + + CD P D + K+C
Sbjct: 92 LDPTPVARCSVRQLKEHAVEGDC-DFQLLKLDGKFSVVYAKCDSSP--DSAEDVRKVCQD 148
Query: 267 CPRDIPTNSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFIDFVARET 326
CP P N + + NA+NN + F+++ + +A++ + Y ++F T
Sbjct: 149 CPLLAPLNDTRVVHAAKAALAAFNAQNNGS-NFQLEEISRAQLVPLPPSTY-VEFTVSGT 206
Query: 327 TC-SKESNE 334
C +KE+ E
Sbjct: 207 DCVAKEATE 215
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 406 HTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRG-HGLGHG 464
H S + G G + R+ H + + GHG + GH RG HG G G
Sbjct: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQ-HGSGSRQSSGHGRQGS-GSGHSPSRGRHGSGSG 2193
Query: 465 HEQ---QHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKT 521
H QHG G G + E + GH G +H+ G GH ++ H +
Sbjct: 2194 HSSSHGQHGSGSG-RSSSRGPYESRSGHSSVFG-QHESGSGHSSAYSQHGSGSGHFCSQG 2251
Query: 522 EHLASSSEDST 532
+H ++S + ST
Sbjct: 2252 QHGSTSGQSST 2262
Score = 38.1 bits (87), Expect = 0.025
Identities = 35/158 (22%), Positives = 53/158 (33%), Gaps = 8/158 (5%)
Query: 384 GFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWG-------HEKQ 436
GFS +SS S S Q R +G R G H
Sbjct: 230 GFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSG 289
Query: 437 RKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGL-GHGHKFKLDDDLEHQGGHVLDHGH 495
+ +LGHG + + HG G GH HG G G + G
Sbjct: 290 SRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFG 349
Query: 496 KHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTT 533
+H+ G G +K H+ + +H ++S + S++
Sbjct: 350 QHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSS 387
Score = 38.1 bits (87), Expect = 0.025
Identities = 38/141 (26%), Positives = 55/141 (39%), Gaps = 25/141 (17%)
Query: 416 ERDSGKEQGHTR-RH--DWGHEKQR-KHNLG---------HGHKHERDQGHGHQRGHGLG 462
++ SG Q +R RH D+GH +H G HG + G GH+ G G
Sbjct: 651 QQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQS 710
Query: 463 HGHEQQHGLGHGHK--FKLDDDLEHQGGHVLDHGH----KHKHG-HGHGKHKNKGK---- 511
G+ QHG G H ++ Q HG +G HG G H++ G
Sbjct: 711 SGY-SQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQG 769
Query: 512 KNGKHNGWKTEHLASSSEDST 532
H+ + H +SS S+
Sbjct: 770 SGSGHSPSRVRHGSSSGHSSS 790
Score = 38.1 bits (87), Expect = 0.025
Identities = 29/105 (27%), Positives = 37/105 (35%), Gaps = 6/105 (5%)
Query: 433 HEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLD 492
+E H+ G GH+ R HG GH HG HG G H
Sbjct: 1510 YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG-QHG---STSGQSSSCGQHGAS 1565
Query: 493 HGHKHKHG-HGHGKHKNKG-KKNGKHNGWKTEHLASSSEDSTTPS 535
G HG HG G ++ G + G +G H S +PS
Sbjct: 1566 SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 1610
Score = 37.4 bits (85), Expect = 0.043
Identities = 29/105 (27%), Positives = 37/105 (35%), Gaps = 6/105 (5%)
Query: 433 HEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLD 492
+E H+ G GH+ R HG GH HG HG G H
Sbjct: 1040 YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG-QHG---STSGQSSSCGQHGAS 1095
Query: 493 HGHKHKHG-HGHGKHKNKG-KKNGKHNGWKTEHLASSSEDSTTPS 535
G HG HG G ++ G + G +G H S +PS
Sbjct: 1096 SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 1140
Score = 37.4 bits (85), Expect = 0.043
Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 15/103 (14%)
Query: 443 HGHKHERDQGHGHQ---------RG-HGLGHGHEQ---QHGLGHGHKFKLDDDLEHQGGH 489
HG + GHG Q RG HG G GH QHG G G + E + GH
Sbjct: 1692 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSG-RSSSRGPYESRSGH 1750
Query: 490 VLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDST 532
G +H+ G GH ++ H + +H ++S + ST
Sbjct: 1751 SSVFG-QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSST 1792
Score = 37.4 bits (85), Expect = 0.043
Identities = 29/105 (27%), Positives = 37/105 (35%), Gaps = 6/105 (5%)
Query: 433 HEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLD 492
+E H+ G GH+ R HG GH HG HG G H
Sbjct: 1980 YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG-QHG---SASGQSSSCGQHGAS 2035
Query: 493 HGHKHKHG-HGHGKHKNKG-KKNGKHNGWKTEHLASSSEDSTTPS 535
G HG HG G ++ G + G +G H S +PS
Sbjct: 2036 SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 2080
Score = 37.4 bits (85), Expect = 0.043
Identities = 29/105 (27%), Positives = 37/105 (35%), Gaps = 6/105 (5%)
Query: 433 HEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLD 492
+E H+ G GH+ R HG GH HG HG G H
Sbjct: 2450 YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHG-QHG---STSGQSSSCGQHGAS 2505
Query: 493 HGHKHKHG-HGHGKHKNKG-KKNGKHNGWKTEHLASSSEDSTTPS 535
G HG HG G ++ G + G +G H S +PS
Sbjct: 2506 SGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 2550
Score = 36.2 bits (82), Expect = 0.096
Identities = 32/128 (25%), Positives = 41/128 (32%), Gaps = 15/128 (11%)
Query: 419 SGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQG-HGHQRGHGLGHGHEQ---------Q 468
SG+ GH +R + G G G HG G G GH+ Q
Sbjct: 887 SGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQ 946
Query: 469 HGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKK-NGKHNGWKTEHLASS 527
HG G GH E G +HG G + G+ +G S
Sbjct: 947 HGSGSGH----SSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1002
Query: 528 SEDSTTPS 535
S S +PS
Sbjct: 1003 SGQSPSPS 1010
Score = 36.2 bits (82), Expect = 0.096
Identities = 25/107 (23%), Positives = 35/107 (32%), Gaps = 6/107 (5%)
Query: 406 HTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGH 465
H S + G GH+ +G R G +H G G HG
Sbjct: 2580 HESSSGQSSSYSQHGSGSGHSS--GYGQHGSRSGQSSRGERHGSSSGSSSHYGQ---HGS 2634
Query: 466 EQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHG-HGHGKHKNKGK 511
+ GHG + +G H GH HG HG G ++ +
Sbjct: 2635 GSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR 2681
Score = 35.8 bits (81), Expect = 0.13
Identities = 25/107 (23%), Positives = 35/107 (32%), Gaps = 6/107 (5%)
Query: 406 HTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGH 465
H S + G GH+ +G R G +H G G HG
Sbjct: 1170 HESSSGQSSSYSQHGSGSGHSS--GYGQHGSRSGQSSRGERHGSSSGSSSHYGQ---HGS 1224
Query: 466 EQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHG-HGHGKHKNKGK 511
+ GHG + +G H GH HG HG G ++ +
Sbjct: 1225 GSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR 1271
Score = 35.0 bits (79), Expect = 0.21
Identities = 33/140 (23%), Positives = 46/140 (32%), Gaps = 14/140 (10%)
Query: 390 SSRIGEIKEETTVSPPHTSMAPAQDEERDSGKE-QGHTRRHDWG-HEKQRKHNLGHGHKH 447
SS G+ + SP H + SG+ G R G + ++ G GH
Sbjct: 410 SSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHE 469
Query: 448 ERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHG------- 500
+ HG G GH HG HG + E QG +HG
Sbjct: 470 SSSEHSSGYTQHGSGSGHSSGHG-QHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSL 528
Query: 501 ----HGHGKHKNKGKKNGKH 516
HG G ++ G+H
Sbjct: 529 GHSRHGSGSGQSPSPSRGRH 548
Score = 35.0 bits (79), Expect = 0.21
Identities = 33/136 (24%), Positives = 52/136 (38%), Gaps = 21/136 (15%)
Query: 419 SGKEQGHTRRHDWGHEKQRKHNLG-HGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKF 477
SG+ GH +R G ++ + G HG R G Q G GLG + G GH
Sbjct: 2532 SGQSPGHGQR---GSGSRQSPSYGRHGSGSGRSSSSG-QHGSGLG----ESSGFGH---- 2579
Query: 478 KLDDDLEHQGGHVLDHGHKHKHGHGHGKH------KNKGKKNGKHNGWKTEHLASSSEDS 531
+ Q HG H G+G+H ++G+++G +G + + S
Sbjct: 2580 --HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSR 2637
Query: 532 TTPSAQTQEKTEGPTP 547
+ Q G +P
Sbjct: 2638 QSSGHGRQGSGSGQSP 2653
Score = 34.7 bits (78), Expect = 0.28
Identities = 33/136 (24%), Positives = 52/136 (38%), Gaps = 21/136 (15%)
Query: 419 SGKEQGHTRRHDWGHEKQRKHNLG-HGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKF 477
SG+ GH +R G ++ + G HG R G Q G GLG + G GH
Sbjct: 1122 SGQSPGHGQR---GSGSRQSPSYGRHGSGSGRSSSSG-QHGSGLG----ESSGFGH---- 1169
Query: 478 KLDDDLEHQGGHVLDHGHKHKHGHGHGKH------KNKGKKNGKHNGWKTEHLASSSEDS 531
+ Q HG H G+G+H ++G+++G +G + + S
Sbjct: 1170 --HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSR 1227
Query: 532 TTPSAQTQEKTEGPTP 547
+ Q G +P
Sbjct: 1228 QSSGHGRQGSGSGHSP 1243
Score = 34.7 bits (78), Expect = 0.28
Identities = 30/129 (23%), Positives = 43/129 (33%), Gaps = 10/129 (7%)
Query: 424 GHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRG-------HGLGHGHEQQHGL-GHGH 475
GH W +H G GH +Q HG + G HG G +G G G
Sbjct: 1402 GHHESSSWQSSGCTQHGSGSGHSSSYEQ-HGSRSGQSSRGERHGSSSGSSSSYGQHGSGS 1460
Query: 476 KFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPS 535
+ L G + +HG G G+ + G +GW + S S +
Sbjct: 1461 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ-SSSYSPYGSGSGWSSSRGPYESGSSHSSG 1519
Query: 536 AQTQEKTEG 544
+E G
Sbjct: 1520 LGHRESRSG 1528
Score = 34.3 bits (77), Expect = 0.37
Identities = 27/117 (23%), Positives = 42/117 (35%), Gaps = 11/117 (9%)
Query: 442 GHGHKHERDQGHGHQRGHGLGHGHEQ---QHG--LGHGHKFKLDDDLEHQGGHVLDHGHK 496
GHG + + HG G G QHG LG F + Q HG
Sbjct: 2067 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSG 2126
Query: 497 HKHGHGHGKH------KNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEGPTP 547
H G+G+H ++G+++G +G + + S + Q G +P
Sbjct: 2127 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSP 2183
Score = 33.9 bits (76), Expect = 0.48
Identities = 27/118 (22%), Positives = 42/118 (35%), Gaps = 13/118 (11%)
Query: 419 SGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQ---HGLGHGH 475
SG+ + ++ H+ + G G + G HG G G HG G G
Sbjct: 173 SGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQ-----HGSGSGQSSSNDTHGSGSGQ 227
Query: 476 K--FKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDS 531
F Q HG H G+G+H G ++G+ + + +S S S
Sbjct: 228 SSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQH---GSRSGQSSRGERHRSSSGSSSS 282
Score = 33.9 bits (76), Expect = 0.48
Identities = 33/115 (28%), Positives = 48/115 (41%), Gaps = 20/115 (17%)
Query: 419 SGKEQGHTRRHDWGHEKQRKHNLG-HGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKF 477
SG+ GH +R G ++ + G HG R G Q G GLG + G GH
Sbjct: 1592 SGQSPGHGQR---GSGSRQSPSYGRHGSGSGRSSSSG-QHGSGLG----ESSGFGH---- 1639
Query: 478 KLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDST 532
+ Q HG H G+G+H G ++G+ + + E SSS S+
Sbjct: 1640 --HESSSGQSSSYSQHGSGSGHSSGYGQH---GSRSGQSS--RGERHGSSSRSSS 1687
Score = 33.5 bits (75), Expect = 0.62
Identities = 24/107 (22%), Positives = 35/107 (32%), Gaps = 6/107 (5%)
Query: 406 HTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGH 465
H S + G GH+ +G R G +H + G HG
Sbjct: 1640 HESSSGQSSSYSQHGSGSGHSS--GYGQHGSRSGQSSRGERHGSSSRSSSRYGQ---HGS 1694
Query: 466 EQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHG-HGHGKHKNKGK 511
+ GHG + +G H GH HG HG G ++ +
Sbjct: 1695 GSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR 1741
Score = 33.5 bits (75), Expect = 0.62
Identities = 35/154 (22%), Positives = 48/154 (31%), Gaps = 33/154 (21%)
Query: 416 ERDSGKEQGHTR-RHDWGH---EKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQ---- 467
++ SG Q +R RH G +H G G + HG G G GH +
Sbjct: 1821 QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGR-HGSGSGQSSGFGHHESSSW 1879
Query: 468 ------QHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKT 521
QHG G GH + G + G HG G+H
Sbjct: 1880 QSSGYTQHGSGSGHSSSYEQHGSRSG--------QSSRGEQHGSSSGSSSSYGQHGSGSR 1931
Query: 522 EHLASSSEDSTTPSAQTQEKTEGPTPIPSLAKPG 555
+ L S + G +P PS + G
Sbjct: 1932 QSLGHGQHGSGS----------GQSPSPSRGRHG 1955
Score = 33.5 bits (75), Expect = 0.62
Identities = 35/154 (22%), Positives = 48/154 (31%), Gaps = 33/154 (21%)
Query: 416 ERDSGKEQGHTR-RHDWGH---EKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQ---- 467
++ SG Q +R RH G +H G G + HG G G GH +
Sbjct: 2291 QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGR-HGSGSGQSSGFGHHESSSW 2349
Query: 468 ------QHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKT 521
QHG G GH + G + G HG G+H
Sbjct: 2350 QSSGYTQHGSGSGHSSSYEQHGSRSG--------QSSRGERHGSSSGSSSSYGQHGSGSR 2401
Query: 522 EHLASSSEDSTTPSAQTQEKTEGPTPIPSLAKPG 555
+ L S + G +P PS + G
Sbjct: 2402 QSLGHGQHGSGS----------GQSPSPSRGRHG 2425
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/117 (22%), Positives = 39/117 (33%), Gaps = 14/117 (11%)
Query: 408 SMAPAQDEERDSGKEQGHTRRHDWG---------HEKQRKHNLGHGHKHERDQGHGHQRG 458
S +P++ ++ H +G +E H+ G GH+ R
Sbjct: 540 SPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQ 599
Query: 459 HGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGK 515
HG GH HG HG G H G HG HG ++ + G+
Sbjct: 600 HGSSSGHSSTHG-QHG---STSGQSSSCGQHGATSGQSSSHGQ-HGSGSSQSSRYGQ 651
Score = 32.7 bits (73), Expect = 1.1
Identities = 31/140 (22%), Positives = 41/140 (29%), Gaps = 40/140 (28%)
Query: 438 KHNLGHGH-----KHERDQG-------HGHQRGHGLGHGHEQ----------QHGLGHGH 475
+H G GH +H G HG G G GH + QHG G GH
Sbjct: 1364 RHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGH 1423
Query: 476 KFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPS 535
+ G + G HG G+H + L S +
Sbjct: 1424 SSSYEQHGSRSG--------QSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS-- 1473
Query: 536 AQTQEKTEGPTPIPSLAKPG 555
G +P PS + G
Sbjct: 1474 --------GQSPSPSRGRHG 1485
Score = 32.3 bits (72), Expect = 1.4
Identities = 42/181 (23%), Positives = 61/181 (33%), Gaps = 19/181 (10%)
Query: 384 GFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSGKE-QGHTRRHDWG-HEKQRKHNL 441
G +SS G + SP H + G+ G R G H +
Sbjct: 1576 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESS 1635
Query: 442 GHGHKHERDQG-------HGHQRGHGLGHGH------EQQHGLGHGHKFKLDDDL-EHQG 487
G GH HE G HG GH G+G + G HG + +H
Sbjct: 1636 GFGH-HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGS 1694
Query: 488 GHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEGPTP 547
G GH + G G G+ ++G ++G G + H S + S E G +
Sbjct: 1695 GSRQSSGHG-RQGSGSGQSPSRG-RHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSS 1752
Query: 548 I 548
+
Sbjct: 1753 V 1753
>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1704
Score = 39.7 bits (91), Expect = 0.009
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 19/77 (24%)
Query: 439 HNLGHG--HKHERDQGHG--HQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHG 494
H+LG+ H E + GHG H G+G+GHG HG G+G + + HG
Sbjct: 1469 HSLGNALVHGGELEMGHGGTHGFGYGVGHGLSHIHGDGYG-----------EASQDVIHG 1517
Query: 495 HKHKHGHGHGKHKNKGK 511
GHG G+ KN+ K
Sbjct: 1518 ----DGHGLGQEKNQQK 1530
Score = 38.1 bits (87), Expect = 0.025
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 18/71 (25%)
Query: 443 HGHKH----ERDQGHG----HQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHG 494
HGH H + D G G H G+ L HG E + G G H F G+ + HG
Sbjct: 1449 HGHSHSLGLDLDLGLGSGTFHSLGNALVHGGELEMGHGGTHGF----------GYGVGHG 1498
Query: 495 HKHKHGHGHGK 505
H HG G+G+
Sbjct: 1499 LSHIHGDGYGE 1509
Score = 33.1 bits (74), Expect = 0.81
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 13/57 (22%)
Query: 422 EQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHG-------HQRGHGLGHGHEQQHGL 471
E GH H +G+ +GHG H G+G H GHGLG QQ L
Sbjct: 1482 EMGHGGTHGFGY------GVGHGLSHIHGDGYGEASQDVIHGDGHGLGQEKNQQKDL 1532
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 39.7 bits (91), Expect = 0.009
Identities = 52/233 (22%), Positives = 77/233 (33%), Gaps = 22/233 (9%)
Query: 330 KESNEELTESCETKKLGQSLDCNAEVYVVPWEKKIYP----TVNCQPLGMISLMKRPPGF 385
KE ++ E+ +T + + N+ V P P P+ IS + R
Sbjct: 963 KEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMM 1022
Query: 386 SPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHE----KQRKHNL 441
+PF I + P P +D RD +E RR G + H L
Sbjct: 1023 TPFMG--ISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRL 1080
Query: 442 GHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQ-GGHVLDHGHKH--- 497
+E D+ + H H H H H +D EH+ GGH+ + H
Sbjct: 1081 STPRLYEADRSFRDREPHDYSHHHHHHH-----HPLSVDPRREHERGGHLDERERLHMLR 1135
Query: 498 ---KHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEGPTP 547
+H H H + H T L S +P+A Q TP
Sbjct: 1136 EDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTP 1188
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 39.7 bits (91), Expect = 0.009
Identities = 52/233 (22%), Positives = 77/233 (33%), Gaps = 22/233 (9%)
Query: 330 KESNEELTESCETKKLGQSLDCNAEVYVVPWEKKIYP----TVNCQPLGMISLMKRPPGF 385
KE ++ E+ +T + + N+ V P P P+ IS + R
Sbjct: 987 KEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMM 1046
Query: 386 SPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHE----KQRKHNL 441
+PF I + P P +D RD +E RR G + H L
Sbjct: 1047 TPFMG--ISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRL 1104
Query: 442 GHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQ-GGHVLDHGHKH--- 497
+E D+ + H H H H H +D EH+ GGH+ + H
Sbjct: 1105 STPRLYEADRSFRDREPHDYSHHHHHHH-----HPLSVDPRREHERGGHLDERERLHMLR 1159
Query: 498 ---KHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEGPTP 547
+H H H + H T L S +P+A Q TP
Sbjct: 1160 EDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTP 1212
>gi|222418633 family with sequence similarity 71, member B [Homo
sapiens]
Length = 605
Score = 39.3 bits (90), Expect = 0.011
Identities = 38/164 (23%), Positives = 58/164 (35%), Gaps = 14/164 (8%)
Query: 416 ERDSGKEQGHTRRHDWGHEKQRKHNL----GHGHKHERDQGHGHQRGHGLGHGHEQQHGL 471
ERD ++ W K+R+ H R G H+R G + H
Sbjct: 410 ERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRS 469
Query: 472 GHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHG-KHKNKGKKNGKHNGWKTEHLASSSED 530
GHK DD E G+ + G HG K+ + K T+ L +
Sbjct: 470 ASGHKNTRDDKKE--------KGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSA 521
Query: 531 STTPSAQTQEKTEGPTPIPSLAKPG-VTVTFSDFQDSDLIATMM 573
S+T + Q + A PG T S ++ D++A M+
Sbjct: 522 SSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMV 565
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 38.5 bits (88), Expect = 0.019
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 16/67 (23%)
Query: 439 HNLGHG--HKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHK 496
H+LG+ H E + GHG G G G G HGL H H G+ ++HG
Sbjct: 1479 HSLGNALVHGGELEMGHGGTHGFGYGVG----HGLSH----------IHGDGYGVNHGGH 1524
Query: 497 HKHGHGH 503
+ HG GH
Sbjct: 1525 YGHGGGH 1531
Score = 37.4 bits (85), Expect = 0.043
Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 6/72 (8%)
Query: 443 HGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHG 502
HGH H G G G G H + L HG + ++ H G+ + HG H HG G
Sbjct: 1459 HGHSHSL--GLDLNLGLGSGTFHSLGNALVHGGELEMGHGGTHGFGYGVGHGLSHIHGDG 1516
Query: 503 ----HGKHKNKG 510
HG H G
Sbjct: 1517 YGVNHGGHYGHG 1528
Score = 32.7 bits (73), Expect = 1.1
Identities = 24/73 (32%), Positives = 30/73 (41%), Gaps = 6/73 (8%)
Query: 453 HGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGH--GHGKHKNKG 510
HGH GL + GLG G L + L H G + HG H G+ GHG G
Sbjct: 1459 HGHSHSLGL----DLNLGLGSGTFHSLGNALVHGGELEMGHGGTHGFGYGVGHGLSHIHG 1514
Query: 511 KKNGKHNGWKTEH 523
G ++G H
Sbjct: 1515 DGYGVNHGGHYGH 1527
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 38.5 bits (88), Expect = 0.019
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 16/67 (23%)
Query: 439 HNLGHG--HKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHK 496
H+LG+ H E + GHG G G G G HGL H H G+ ++HG
Sbjct: 1469 HSLGNALVHGGELEMGHGGTHGFGYGVG----HGLSH----------IHGDGYGVNHGGH 1514
Query: 497 HKHGHGH 503
+ HG GH
Sbjct: 1515 YGHGGGH 1521
Score = 37.4 bits (85), Expect = 0.043
Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 6/72 (8%)
Query: 443 HGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHG 502
HGH H G G G G H + L HG + ++ H G+ + HG H HG G
Sbjct: 1449 HGHSHSL--GLDLNLGLGSGTFHSLGNALVHGGELEMGHGGTHGFGYGVGHGLSHIHGDG 1506
Query: 503 ----HGKHKNKG 510
HG H G
Sbjct: 1507 YGVNHGGHYGHG 1518
Score = 32.7 bits (73), Expect = 1.1
Identities = 24/73 (32%), Positives = 30/73 (41%), Gaps = 6/73 (8%)
Query: 453 HGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGH--GHGKHKNKG 510
HGH GL + GLG G L + L H G + HG H G+ GHG G
Sbjct: 1449 HGHSHSLGL----DLNLGLGSGTFHSLGNALVHGGELEMGHGGTHGFGYGVGHGLSHIHG 1504
Query: 511 KKNGKHNGWKTEH 523
G ++G H
Sbjct: 1505 DGYGVNHGGHYGH 1517
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,073,536
Number of Sequences: 37866
Number of extensions: 1436294
Number of successful extensions: 5394
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 4269
Number of HSP's gapped (non-prelim): 681
length of query: 644
length of database: 18,247,518
effective HSP length: 109
effective length of query: 535
effective length of database: 14,120,124
effective search space: 7554266340
effective search space used: 7554266340
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.