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Search of human proteins with 15619013
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15619013 43 kD receptor-associated protein of the synapse
isoform 1 [Homo sapiens]
(412 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15619013 43 kD receptor-associated protein of the synapse iso... 836 0.0
gi|38045928 43 kD receptor-associated protein of the synapse iso... 654 0.0
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 87 3e-17
gi|164519122 LGN protein [Homo sapiens] 57 4e-08
gi|224548927 G-protein signaling modulator 1 (AGS3-like, C. eleg... 55 9e-08
gi|224548925 G-protein signaling modulator 1 (AGS3-like, C. eleg... 55 9e-08
gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens] 42 0.001
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 40 0.003
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 40 0.003
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 40 0.003
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens] 40 0.004
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens] 40 0.004
gi|71043932 zinc finger, SWIM domain containing 2 [Homo sapiens] 39 0.007
gi|34452686 ring finger protein, LIM domain interacting [Homo sa... 39 0.009
gi|34452684 ring finger protein, LIM domain interacting [Homo sa... 39 0.009
gi|37595553 ring finger protein 111 [Homo sapiens] 39 0.009
gi|150170725 zinc and ring finger 4 [Homo sapiens] 39 0.011
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 38 0.015
gi|58331195 ring finger and CHY zinc finger domain containing 1 ... 37 0.025
gi|4503729 FK506 binding protein 52 [Homo sapiens] 37 0.033
gi|157412255 praja 2, RING-H2 motif containing [Homo sapiens] 37 0.043
gi|21071001 autocrine motility factor receptor [Homo sapiens] 37 0.043
gi|5031825 ring finger protein 103 [Homo sapiens] 37 0.043
gi|188497705 BRCA1 associated protein [Homo sapiens] 36 0.056
gi|32454739 tripartite motif-containing 3 [Homo sapiens] 36 0.056
gi|32454737 tripartite motif-containing 3 [Homo sapiens] 36 0.056
gi|7706039 ring finger protein 181 [Homo sapiens] 36 0.056
gi|27436927 synoviolin 1 isoform b [Homo sapiens] 36 0.073
gi|27436925 synoviolin 1 isoform a [Homo sapiens] 36 0.073
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 36 0.073
>gi|15619013 43 kD receptor-associated protein of the synapse
isoform 1 [Homo sapiens]
Length = 412
Score = 836 bits (2159), Expect = 0.0
Identities = 412/412 (100%), Positives = 412/412 (100%)
Query: 1 MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60
MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK
Sbjct: 1 MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60
Query: 61 EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120
EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ
Sbjct: 61 EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120
Query: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180
LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE
Sbjct: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180
Query: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240
KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG
Sbjct: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240
Query: 241 DRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARK 300
DRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARK
Sbjct: 241 DRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARK 300
Query: 301 ALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEETE 360
ALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEETE
Sbjct: 301 ALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEETE 360
Query: 361 LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 412
LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV
Sbjct: 361 LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 412
>gi|38045928 43 kD receptor-associated protein of the synapse
isoform 2 [Homo sapiens]
Length = 353
Score = 654 bits (1686), Expect = 0.0
Identities = 335/412 (81%), Positives = 343/412 (83%), Gaps = 59/412 (14%)
Query: 1 MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60
MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK
Sbjct: 1 MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYK 60
Query: 61 EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120
EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ
Sbjct: 61 EMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQ 120
Query: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180
LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE
Sbjct: 121 LGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYE 180
Query: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240
KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG
Sbjct: 181 KALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHG 240
Query: 241 DRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARK 300
DRPLQALCLLCFADIHRSRGDLE +++
Sbjct: 241 DRPLQALCLLCFADIHRSRGDLE---------------------------------LSQL 267
Query: 301 ALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEETE 360
L ++I R++ L E+ RAHVVRFHECVEETE
Sbjct: 268 KLHCLSESIYRSKGLQREL--------------------------RAHVVRFHECVEETE 301
Query: 361 LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 412
LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV
Sbjct: 302 LYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV 353
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 87.0 bits (214), Expect = 3e-17
Identities = 95/420 (22%), Positives = 170/420 (40%), Gaps = 66/420 (15%)
Query: 38 DLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLC 97
D+ G +V L AH +G Y+E +K+ + A++L D ++Y NL + + L
Sbjct: 629 DMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALL 688
Query: 98 EFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNND 157
F K K L L + +Q + ++G+ F+ A++ +E+ L AH
Sbjct: 689 NFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVK 748
Query: 158 DAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYR 217
D LE +LG+ Y ++ Y+KAL + + E+ Y + L + H+A Y
Sbjct: 749 DRRLEASAYAALGTAYRMIQKYDKALGYHTQELEV---YQELSDLPGECRAHGHLAAVYM 805
Query: 218 LLGRLGSAMECCEESMKIALQHGDRPLQA--------------------------LCLL- 250
LG+ A +C EE + + + D L+A L +L
Sbjct: 806 ALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQ 865
Query: 251 ----------------CFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAK 294
D + + GD E A Y+ +S+ + Q +A G+
Sbjct: 866 QLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGN 925
Query: 295 CWVARKALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKG--------LQRELR 346
A +L +AL E+ +A E+G ++ + + S++ G L+R+L
Sbjct: 926 GHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNYEQAISCLERQL- 984
Query: 347 AHVVR-FHECVEETELYCGLCG--ESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCR 403
++ R + E++ CGL G + +GE ++ LQ +H LQ + P C+
Sbjct: 985 -NIARDMKDRALESDAACGLGGVYQQMGEYDTALQ-------YHQLDLQIAEETNNPTCQ 1036
Score = 69.7 bits (169), Expect = 5e-12
Identities = 72/330 (21%), Positives = 139/330 (42%), Gaps = 6/330 (1%)
Query: 22 TEKA---LQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELED 78
TEK+ +Q V + D G R G L +A G Y+E L Q+ A +L+D
Sbjct: 250 TEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKD 309
Query: 79 ADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSV 138
+ + +L + ++ ++ K C+ L + +MG ++ +
Sbjct: 310 REAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGD 369
Query: 139 FQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGK 198
F+ A++ E+ L+ A + + E R +LGS Y ++++KA+ + EL +
Sbjct: 370 FENAVQCHEQHLKIAKDLGNKREEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELME 429
Query: 199 GWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRS 258
+++ RA + + A R + L A + E+ + IA DR + IH+
Sbjct: 430 K-AIEMRAYAG--LGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQM 486
Query: 259 RGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARKALDKALDAIERAQDLAEE 318
+GD +TA + + + I E+ + Q +A + + A D+A+ + ++ E
Sbjct: 487 KGDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISME 546
Query: 319 VGNKLSQLKLHCLSESIYRSKGLQRELRAH 348
V ++ SQ H Y++ G H
Sbjct: 547 VNDRASQASTHGNLAVAYQALGAHDRALQH 576
Score = 63.9 bits (154), Expect = 2e-10
Identities = 78/370 (21%), Positives = 148/370 (40%), Gaps = 56/370 (15%)
Query: 23 EKALQVWTKVLE---KSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDA 79
+KAL T+ LE + SDL G R G L + +G+Y K Q+D ++L+D
Sbjct: 771 DKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDP 830
Query: 80 DFLLE-------------------------------------------SYLNLARSNEKL 96
+ +Y NL E L
Sbjct: 831 SLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEAL 890
Query: 97 CEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNN 156
++ + I Y + L + + Q + +GN + Q+AL FEK L AH
Sbjct: 891 GDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHEL 950
Query: 157 DDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAM---SQYHMA 213
+A + + LGS ++Q+ +YE+A+ C +L N + +K RA+ + +
Sbjct: 951 GEAFNKAQAYGELGSLHSQLGNYEQAI--SCLERQL--NIAR--DMKDRALESDAACGLG 1004
Query: 214 VAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLETAFPRYDSAM 273
Y+ +G +A++ + ++IA + + Q + S G E A + +
Sbjct: 1005 GVYQQMGEYDTALQYHQLDLQIAEETNNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHL 1064
Query: 274 SIMTEIGNRLGQVQALLGVAKCWVARKALDKALDAIERAQDLAEEVGNKLSQLKL-HCLS 332
SI ++ + + + + + A + +A+ ++ LAE++G + + K+ H L
Sbjct: 1065 SIAAQMNDLAAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEAKIRHGLG 1124
Query: 333 ESIYRSKGLQ 342
S++ S L+
Sbjct: 1125 LSLWASGNLE 1134
Score = 63.5 bits (153), Expect = 3e-10
Identities = 56/309 (18%), Positives = 134/309 (43%), Gaps = 3/309 (0%)
Query: 32 VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLAR 91
+ ++ SD + R G + A++ +G Y + +K+ ++ + E+ D ++ NLA
Sbjct: 503 IAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAV 562
Query: 92 SNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALR 151
+ + L + + + + L + Q + ++GN + +A +E+ LR
Sbjct: 563 AYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLR 622
Query: 152 YAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYH 211
A + D E +VC +LG + + +Y++A+ + + L + S +A + +
Sbjct: 623 LAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLS---QAKAYCN 679
Query: 212 MAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLETAFPRYDS 271
+ +A++ L A EC + + +A + + L DI + D+ A Y+
Sbjct: 680 LGLAFKALLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQ 739
Query: 272 AMSIMTEIGNRLGQVQALLGVAKCWVARKALDKALDAIERAQDLAEEVGNKLSQLKLHCL 331
+ + ++ +R + A + + + DKAL + ++ +E+ + + + H
Sbjct: 740 QLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGH 799
Query: 332 SESIYRSKG 340
++Y + G
Sbjct: 800 LAAVYMALG 808
Score = 54.7 bits (130), Expect = 2e-07
Identities = 60/333 (18%), Positives = 128/333 (38%), Gaps = 16/333 (4%)
Query: 16 LYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARE 75
L ++ E+ + + + ++ +FR LG L +KF Q+ A +
Sbjct: 687 LLNFSKAEECQKYLLSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQ 746
Query: 76 LEDADFLLESYLNLARSNEKLCEFHKTISYCKTCL-------GLPGT-RAGAQLGGQVSL 127
++D +Y L + + ++ K + Y L LPG RA L
Sbjct: 747 VKDRRLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHLAA---- 802
Query: 128 SMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPC 187
++ L + A + +E+ L D LE +V ++G + E+A+ +
Sbjct: 803 ----VYMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFE 858
Query: 188 KAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQAL 247
+ ++ S+ R + ++ Y LG A++ E+ + +A QA
Sbjct: 859 QQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAK 918
Query: 248 CLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARKALDKALD 307
+ HR+ G L+ A ++ + + E+G + QA + ++A+
Sbjct: 919 AYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNYEQAIS 978
Query: 308 AIERAQDLAEEVGNKLSQLKLHCLSESIYRSKG 340
+ER ++A ++ ++ + C +Y+ G
Sbjct: 979 CLERQLNIARDMKDRALESDAACGLGGVYQQMG 1011
Score = 52.8 bits (125), Expect = 6e-07
Identities = 52/254 (20%), Positives = 106/254 (41%), Gaps = 6/254 (2%)
Query: 128 SMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPC 187
++G+AF +++AL + L A D SLG Y + DY AL
Sbjct: 279 NLGSAFFSKGNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASH- 337
Query: 188 KAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQAL 247
K L+ K + R + +M Y +G +A++C E+ +KIA G++ +A
Sbjct: 338 KQCVLLAKQSKDELSEARELG--NMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEAR 395
Query: 248 CLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARKALDKALD 307
+ R + + A ++ + + E+ + +++A G+ + L++A
Sbjct: 396 AYSNLGSAYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQ 455
Query: 308 AIERAQDLAEEVGNKLSQLKLHCLSESIYRSKG-LQRELRAHVVRFHECVEETELYCGLC 366
E+ +AE++ ++ ++ + I++ KG L+ H + H C+ +
Sbjct: 456 YHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLH--KTHLCIAQELSDYAAQ 513
Query: 367 GESIGEKNSRLQAL 380
G + G + AL
Sbjct: 514 GRAYGNMGNAYNAL 527
Score = 50.4 bits (119), Expect = 3e-06
Identities = 49/230 (21%), Positives = 98/230 (42%), Gaps = 4/230 (1%)
Query: 120 QLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDY 179
+L G V ++ +A+ L +K+ ++ L A D ECR +LGS + +Y
Sbjct: 231 KLRGSVFSALSSAYWSLGNTEKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNY 290
Query: 180 EKALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQH 239
+AL L + S H+ Y +G +A+ ++ + +A Q
Sbjct: 291 REALTNHRHQLVLAMKLKDREAASSALSSLGHV---YTAIGDYPNALASHKQCVLLAKQS 347
Query: 240 GDRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVAR 299
D +A L ++ + GD E A ++ + I ++GN+ + +A + + R
Sbjct: 348 KDELSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEARAYSNLGSAYHYR 407
Query: 300 KALDKALDAIERAQDLAEEVGNKLSQLKLHC-LSESIYRSKGLQRELRAH 348
+ DKA+ +LA+E+ K +++ + L + + L+R + H
Sbjct: 408 RNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYH 457
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/199 (20%), Positives = 86/199 (43%), Gaps = 3/199 (1%)
Query: 3 QDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRF---RVLGCLVTAHSEMGRY 59
QDQ K G ++AL + K L + +L F + G L + HS++G Y
Sbjct: 914 QDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNY 973
Query: 60 KEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGA 119
++ + Q++ AR+++D ++ L +++ E+ + Y + L +
Sbjct: 974 EQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQIAEETNNP 1033
Query: 120 QLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDY 179
G+ ++G + L F++A+ E+ L A +D + SLG + +++Y
Sbjct: 1034 TCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQNY 1093
Query: 180 EKALFFPCKAAELVNNYGK 198
+A+ + + L G+
Sbjct: 1094 SQAVMYLQEGLRLAEQLGR 1112
>gi|164519122 LGN protein [Homo sapiens]
Length = 684
Score = 56.6 bits (135), Expect = 4e-08
Identities = 44/194 (22%), Positives = 82/194 (42%), Gaps = 9/194 (4%)
Query: 4 DQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEML 63
++ + ++ + Y+ N + ++ D + R G L H +G +++ +
Sbjct: 172 EEVRDALQAAVDFYEENLS---------LVTALGDRAAQGRAFGNLGNTHYLLGNFRDAV 222
Query: 64 KFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGG 123
++ A+E D +Y NL + L EF Y K L L +
Sbjct: 223 IAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEA 282
Query: 124 QVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKAL 183
Q S+GN + L ++KA++ K L A +D + E R C SLG+ Y + ++++A+
Sbjct: 283 QSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAM 342
Query: 184 FFPCKAAELVNNYG 197
F K E+ G
Sbjct: 343 HFAEKHLEISREVG 356
Score = 52.8 bits (125), Expect = 6e-07
Identities = 59/290 (20%), Positives = 119/290 (41%), Gaps = 25/290 (8%)
Query: 38 DLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLC 97
D +G + G L +G + E + +D +REL D + NL
Sbjct: 97 DQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGN------ 150
Query: 98 EFHKTISYCK-TCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNN 156
+ + K G PG + + +V Q A++ +E+ L
Sbjct: 151 -----VYHAKGKSFGCPGPQDVGEFPEEVR----------DALQAAVDFYEENLSLVTAL 195
Query: 157 DDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYHMAVAY 216
D + R +LG+ + + ++ A+ + + +G + + RA S ++ AY
Sbjct: 196 GDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDK-AAERRAYS--NLGNAY 252
Query: 217 RLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIM 276
LG +A E ++++ +A Q DR ++A + + D E A + ++I
Sbjct: 253 IFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIA 312
Query: 277 TEIGNRLGQVQALLGVAKCWVARKALDKALDAIERAQDLAEEVGNKLSQL 326
E+ +R+G+ +A + + A D+A+ E+ +++ EVG+K +L
Sbjct: 313 QELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKSGEL 362
Score = 52.0 bits (123), Expect = 1e-06
Identities = 71/356 (19%), Positives = 134/356 (37%), Gaps = 40/356 (11%)
Query: 66 AVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLG-GQ 124
A VQ+ T ED L Y L + L ++ K + Y L L T G QLG +
Sbjct: 49 AAVQVGT----EDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLART-IGDQLGEAK 103
Query: 125 VSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALF 184
S ++GN L F +A+ ++ L + +D + E R +LG+ Y + K
Sbjct: 104 ASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVY-----HAKGKS 158
Query: 185 FPCKAAELVNNYGKGWSLKYRAMSQYH----------------------MAVAYRLLGRL 222
F C + V + + +A ++ + + LLG
Sbjct: 159 FGCPGPQDVGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNF 218
Query: 223 GSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNR 282
A+ E+ + IA + GD+ + + + G+ ETA Y + + ++ +R
Sbjct: 219 RDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDR 278
Query: 283 LGQVQALLGVAKCWVARKALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQ 342
+ Q+ + + + +KA+D + +A+E+ +++ + + + Y + G
Sbjct: 279 AVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNH 338
Query: 343 RELRAHVVRFHECVEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRS 398
+ + E E G+ GE +RL + L NN S
Sbjct: 339 DQAMHFAEKHLEISREV-------GDKSGELTARLNLSDLQMVLGLSYSTNNSIMS 387
Score = 31.2 bits (69), Expect = 1.8
Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 3/71 (4%)
Query: 23 EKALQVWTK---VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDA 79
EKA+ K + ++ +D +G R L A++ +G + + + FA ++ +RE+ D
Sbjct: 299 EKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDK 358
Query: 80 DFLLESYLNLA 90
L + LNL+
Sbjct: 359 SGELTARLNLS 369
>gi|224548927 G-protein signaling modulator 1 (AGS3-like, C.
elegans) isoform a [Homo sapiens]
Length = 675
Score = 55.5 bits (132), Expect = 9e-08
Identities = 55/225 (24%), Positives = 90/225 (40%), Gaps = 43/225 (19%)
Query: 70 IDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSM 129
+ +EL D +Y NL ++ L F + ++ K L + + ++
Sbjct: 196 LSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNL 255
Query: 130 GNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKA 189
GNA + L F A E ++K L+ + D +E + C SLG+ Y ++DYE+A + +
Sbjct: 256 GNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLR- 314
Query: 190 AELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCL 249
H+ +A L R+G C S+ A RP QAL
Sbjct: 315 ---------------------HLLIAQELADRVGEGRACW--SLGNAYVSMGRPAQALT- 350
Query: 250 LCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAK 294
FA H + I EIG+R G++ A + VA+
Sbjct: 351 --FAKKH----------------LQISQEIGDRHGELTARMNVAQ 377
Score = 53.9 bits (128), Expect = 3e-07
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 3/193 (1%)
Query: 32 VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLAR 91
++++ D + R G L H +G + E F ++ A+E D +Y NL
Sbjct: 198 LVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGN 257
Query: 92 SNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALR 151
++ L F Y K L L + Q S+GN + L +++A E + L
Sbjct: 258 AHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLL 317
Query: 152 YAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYH 211
A D + E R C SLG+ Y + +AL F K ++ G ++ +
Sbjct: 318 IAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDRHG---ELTARMN 374
Query: 212 MAVAYRLLGRLGS 224
+A +LGRL S
Sbjct: 375 VAQLQLVLGRLTS 387
Score = 45.1 bits (105), Expect = 1e-04
Identities = 38/186 (20%), Positives = 88/186 (47%), Gaps = 3/186 (1%)
Query: 141 KALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGW 200
KA E +E+ L D + R +LG+ + + ++ +A F + + +G
Sbjct: 187 KASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDK- 245
Query: 201 SLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRG 260
+ + RA S ++ A+ LGR A E +++++++ Q D+ ++A + +
Sbjct: 246 AAERRAYS--NLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQ 303
Query: 261 DLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARKALDKALDAIERAQDLAEEVG 320
D E A + + I E+ +R+G+ +A + +V+ +AL ++ +++E+G
Sbjct: 304 DYERAAEYHLRHLLIAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIG 363
Query: 321 NKLSQL 326
++ +L
Sbjct: 364 DRHGEL 369
Score = 42.7 bits (99), Expect = 6e-04
Identities = 56/290 (19%), Positives = 108/290 (37%), Gaps = 54/290 (18%)
Query: 139 FQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGK 198
F+ + FE A++ +D + LG+ Y +K++ +AL + L G
Sbjct: 44 FKTGVAFFEAAVQVG--TEDLKTLSAIYSQLGNAYFYLKEHGRALEYHKHDLLLARTIGD 101
Query: 199 GWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRS 258
A + ++ ++LGR A CC+ + IA + GD+ +A L +++ +
Sbjct: 102 RMG---EAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQGDKVGEARALYNIGNVYHA 158
Query: 259 RG-----------------------DLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKC 295
+G L A Y+ +S++ E+G+R Q +A +
Sbjct: 159 KGKQLSWNAANATQDPGHLPPDVRETLCKASEFYERNLSLVKELGDRAAQGRAYGNLGNT 218
Query: 296 WVARKALDKALDAIERAQDLAEEVGNKLSQLKLH--------------CLSESIYRSKGL 341
+A + +A+E G+K ++ + + +E ++ L
Sbjct: 219 HYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQL 278
Query: 342 QRELRAHVVRFHECVEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCL 391
R+LR V C S+G + LQ + +HLR L
Sbjct: 279 SRQLRDQAVEAQACY------------SLGNTYTLLQDYERAAEYHLRHL 316
>gi|224548925 G-protein signaling modulator 1 (AGS3-like, C.
elegans) isoform b [Homo sapiens]
Length = 457
Score = 55.5 bits (132), Expect = 9e-08
Identities = 55/225 (24%), Positives = 90/225 (40%), Gaps = 43/225 (19%)
Query: 70 IDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSM 129
+ +EL D +Y NL ++ L F + ++ K L + + ++
Sbjct: 196 LSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNL 255
Query: 130 GNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKA 189
GNA + L F A E ++K L+ + D +E + C SLG+ Y ++DYE+A + +
Sbjct: 256 GNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLR- 314
Query: 190 AELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCL 249
H+ +A L R+G C S+ A RP QAL
Sbjct: 315 ---------------------HLLIAQELADRVGEGRACW--SLGNAYVSMGRPAQALT- 350
Query: 250 LCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAK 294
FA H + I EIG+R G++ A + VA+
Sbjct: 351 --FAKKH----------------LQISQEIGDRHGELTARMNVAQ 377
Score = 53.9 bits (128), Expect = 3e-07
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 3/193 (1%)
Query: 32 VLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLAR 91
++++ D + R G L H +G + E F ++ A+E D +Y NL
Sbjct: 198 LVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGN 257
Query: 92 SNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALR 151
++ L F Y K L L + Q S+GN + L +++A E + L
Sbjct: 258 AHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLL 317
Query: 152 YAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGWSLKYRAMSQYH 211
A D + E R C SLG+ Y + +AL F K ++ G ++ +
Sbjct: 318 IAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDRHG---ELTARMN 374
Query: 212 MAVAYRLLGRLGS 224
+A +LGRL S
Sbjct: 375 VAQLQLVLGRLTS 387
Score = 45.1 bits (105), Expect = 1e-04
Identities = 38/186 (20%), Positives = 88/186 (47%), Gaps = 3/186 (1%)
Query: 141 KALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGKGW 200
KA E +E+ L D + R +LG+ + + ++ +A F + + +G
Sbjct: 187 KASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDK- 245
Query: 201 SLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRG 260
+ + RA S ++ A+ LGR A E +++++++ Q D+ ++A + +
Sbjct: 246 AAERRAYS--NLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQ 303
Query: 261 DLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARKALDKALDAIERAQDLAEEVG 320
D E A + + I E+ +R+G+ +A + +V+ +AL ++ +++E+G
Sbjct: 304 DYERAAEYHLRHLLIAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEIG 363
Query: 321 NKLSQL 326
++ +L
Sbjct: 364 DRHGEL 369
Score = 42.7 bits (99), Expect = 6e-04
Identities = 56/290 (19%), Positives = 108/290 (37%), Gaps = 54/290 (18%)
Query: 139 FQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNNYGK 198
F+ + FE A++ +D + LG+ Y +K++ +AL + L G
Sbjct: 44 FKTGVAFFEAAVQVG--TEDLKTLSAIYSQLGNAYFYLKEHGRALEYHKHDLLLARTIGD 101
Query: 199 GWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRS 258
A + ++ ++LGR A CC+ + IA + GD+ +A L +++ +
Sbjct: 102 RMG---EAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQGDKVGEARALYNIGNVYHA 158
Query: 259 RG-----------------------DLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKC 295
+G L A Y+ +S++ E+G+R Q +A +
Sbjct: 159 KGKQLSWNAANATQDPGHLPPDVRETLCKASEFYERNLSLVKELGDRAAQGRAYGNLGNT 218
Query: 296 WVARKALDKALDAIERAQDLAEEVGNKLSQLKLH--------------CLSESIYRSKGL 341
+A + +A+E G+K ++ + + +E ++ L
Sbjct: 219 HYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQL 278
Query: 342 QRELRAHVVRFHECVEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCL 391
R+LR V C S+G + LQ + +HLR L
Sbjct: 279 SRQLRDQAVEAQACY------------SLGNTYTLLQDYERAAEYHLRHL 316
>gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens]
Length = 1208
Score = 41.6 bits (96), Expect = 0.001
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 8/57 (14%)
Query: 357 EETELYCGLCGESIGEKNSRLQALPCSHIFHLRC----LQNNGTRSCPNCRRSSMKP 409
EE E C +C E++ +N L LPC+H FH +C L GT CP CR + P
Sbjct: 1142 EEEEEPCVICHENLSPEN--LSVLPCAHKFHAQCIRPWLMQQGT--CPTCRLHVLLP 1194
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 8/87 (9%)
Query: 81 FLLESYLNLARSNEKLCEFHKTISYCKTCLGL-PGTRAGAQLGGQVSLSMGNAFLGLSVF 139
FLL ++LNLA KL E+ K + C LGL G G+ L M F
Sbjct: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE-------F 367
Query: 140 QKALESFEKALRYAHNNDDAMLECRVC 166
+ A FEK L N A L+ +C
Sbjct: 368 ESAKGDFEKVLEVNPQNKAARLQISMC 394
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 8/87 (9%)
Query: 81 FLLESYLNLARSNEKLCEFHKTISYCKTCLGL-PGTRAGAQLGGQVSLSMGNAFLGLSVF 139
FLL ++LNLA KL E+ K + C LGL G G+ L M F
Sbjct: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE-------F 367
Query: 140 QKALESFEKALRYAHNNDDAMLECRVC 166
+ A FEK L N A L+ +C
Sbjct: 368 ESAKGDFEKVLEVNPQNKAARLQISMC 394
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 8/87 (9%)
Query: 81 FLLESYLNLARSNEKLCEFHKTISYCKTCLGL-PGTRAGAQLGGQVSLSMGNAFLGLSVF 139
FLL ++LNLA KL E+ K + C LGL G G+ L M F
Sbjct: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE-------F 367
Query: 140 QKALESFEKALRYAHNNDDAMLECRVC 166
+ A FEK L N A L+ +C
Sbjct: 368 ESAKGDFEKVLEVNPQNKAARLQISMC 394
>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
Length = 744
Score = 40.0 bits (92), Expect = 0.004
Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 9/59 (15%)
Query: 356 VEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 409
+++ L C +C E KN ++ LPC H F RCLQN + T SCP CR++S+ P
Sbjct: 16 IDKQFLICSICLERY--KNPKV--LPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILP 70
>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
Length = 771
Score = 40.0 bits (92), Expect = 0.004
Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 9/59 (15%)
Query: 356 VEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 409
+++ L C +C E KN ++ LPC H F RCLQN + T SCP CR++S+ P
Sbjct: 43 IDKQFLICSICLERY--KNPKV--LPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILP 97
>gi|71043932 zinc finger, SWIM domain containing 2 [Homo sapiens]
Length = 633
Score = 39.3 bits (90), Expect = 0.007
Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 3/103 (2%)
Query: 300 KALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEET 359
++L+K D + + D E+ K+S + +Y K + R L ++ + +
Sbjct: 283 RSLEKRADEVVKYIDTKNEIEEKMSHFQEK--QGQVYTPKHIVRSLPLQLITKNSKLLAP 340
Query: 360 ELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNC 402
C LC ++ + LPC+H FH +C+ N C +C
Sbjct: 341 GYQCLLCLKAF-HLGQHTRLLPCTHKFHRKCIDNWLFHKCNSC 382
>gi|34452686 ring finger protein, LIM domain interacting [Homo
sapiens]
Length = 624
Score = 38.9 bits (89), Expect = 0.009
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 3/50 (6%)
Query: 363 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMKPG 410
C +C E N +L+ LPCSH +H+ C+ + +CP CRR+ + G
Sbjct: 570 CSVCITEYTEGN-KLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASG 618
>gi|34452684 ring finger protein, LIM domain interacting [Homo
sapiens]
Length = 624
Score = 38.9 bits (89), Expect = 0.009
Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 3/50 (6%)
Query: 363 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMKPG 410
C +C E N +L+ LPCSH +H+ C+ + +CP CRR+ + G
Sbjct: 570 CSVCITEYTEGN-KLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASG 618
>gi|37595553 ring finger protein 111 [Homo sapiens]
Length = 986
Score = 38.9 bits (89), Expect = 0.009
Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 315 LAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEETELYCGLCGESIGEKN 374
L E +GN + Y K +R+L E+TE C +C SI E+
Sbjct: 886 LEERLGNVNRGASQGTIERCTYPHKYKKRKLHCKQDGEEGTEEDTEEKCTIC-LSILEEG 944
Query: 375 SRLQALPCSHIFHLRCLQN--NGTRSCPNCR 403
++ LPC H+FH C+ + CP CR
Sbjct: 945 EDVRRLPCMHLFHQVCVDQWLITNKKCPICR 975
>gi|150170725 zinc and ring finger 4 [Homo sapiens]
Length = 429
Score = 38.5 bits (88), Expect = 0.011
Identities = 17/47 (36%), Positives = 27/47 (57%), Gaps = 5/47 (10%)
Query: 363 CGLCGESIGEKNSRLQALPCSHIFHLRCL----QNNGTRSCPNCRRS 405
C +C + E+ +L+ LPCSH +H +C+ RSCP C++S
Sbjct: 309 CAICLDEY-EEGDQLKILPCSHTYHCKCIDPWFSQAPRRSCPVCKQS 354
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 38.1 bits (87), Expect = 0.015
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 15/105 (14%)
Query: 130 GNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKDYEKALFFPCKA 189
GN L + AL+ + +A++ +N + + + YA+ DY+KA CK
Sbjct: 11 GNKALSVGNIDDALQCYSEAIKLDPHNHV------LYSNRSAAYAKKGDYQKAYEDGCKT 64
Query: 190 AELVNNYGKGWSLKYRAMSQYHMAVAYRLLGRLGSAMECCEESMK 234
+L ++GKG+S K A A L R A EE +K
Sbjct: 65 VDLKPDWGKGYSRK---------AAALEFLNRFEEAKRTYEEGLK 100
>gi|58331195 ring finger and CHY zinc finger domain containing 1
isoform 1 [Homo sapiens]
Length = 261
Score = 37.4 bits (85), Expect = 0.025
Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 13/83 (15%)
Query: 329 HCLSESIYRSKGLQRELRAHVVRFHECVEETELY-CGLCGESIGEKNSRLQALPCSHIFH 387
HCL ++ + LQ H+C+E C +C E I LPC H+ H
Sbjct: 118 HCLKCNLCLAMNLQGR--------HKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLH 169
Query: 388 LRCLQ---NNGTRSCPNCRRSSM 407
C + G R CP C S++
Sbjct: 170 RTCYEEMLKEGYR-CPLCMHSAL 191
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 37.0 bits (84), Expect = 0.033
Identities = 39/153 (25%), Positives = 62/153 (40%), Gaps = 18/153 (11%)
Query: 23 EKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLK-----FAVVQIDTARELE 77
EKA + W E+ + + G T + + G+YK+ L + ++ +++ E
Sbjct: 253 EKAKESWEMNSEEKLEQSTIVKERG---TVYFKEGKYKQALLQYKKIVSWLEYESSFSNE 309
Query: 78 DAD----FLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAF 133
+A L S+LNLA + KL F I C L L G A
Sbjct: 310 EAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLF------RRGEAH 363
Query: 134 LGLSVFQKALESFEKALRYAHNNDDAMLECRVC 166
L ++ F+ A F+K L+ NN A + VC
Sbjct: 364 LAVNDFELARADFQKVLQLYPNNKAAKTQLAVC 396
>gi|157412255 praja 2, RING-H2 motif containing [Homo sapiens]
Length = 708
Score = 36.6 bits (83), Expect = 0.043
Identities = 41/140 (29%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Query: 270 DSAMSIMTEIGNRLGQVQALLGVAKCWVARKALDKAL-DAIERAQDLAEEVGNKLSQLKL 328
D S+ + LG +A+ V ++ AL++ L A+E A E + +
Sbjct: 547 DVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAVDVEVANP 606
Query: 329 HCLSESIYRSKGLQRELRAHVVRFHECVEETELYCGLCGESIGEKNSRLQALPCSHIFHL 388
ESI GL L V+ H + + + C E I K+ LPC H FH
Sbjct: 607 PASKESI---DGLPETL---VLEDHTAIGQEQCCPICCSEYI--KDDIATELPCHHFFHK 658
Query: 389 RC----LQNNGTRSCPNCRR 404
C LQ +GT CP CRR
Sbjct: 659 PCVSIWLQKSGT--CPVCRR 676
>gi|21071001 autocrine motility factor receptor [Homo sapiens]
Length = 643
Score = 36.6 bits (83), Expect = 0.043
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 6/45 (13%)
Query: 363 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRS 405
C +C +S+ + LPC H+FH CL++ SCP CR S
Sbjct: 341 CAICWDSM----QAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMS 381
>gi|5031825 ring finger protein 103 [Homo sapiens]
Length = 685
Score = 36.6 bits (83), Expect = 0.043
Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 4/49 (8%)
Query: 363 CGLCGESIGEKNSRLQALPCSHIFHLRCL---QNNGTRSCPNCRRSSMK 408
C +C E+ E L LPC H+FH C+ G CP CR S K
Sbjct: 621 CVVCLENF-ENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYK 668
>gi|188497705 BRCA1 associated protein [Homo sapiens]
Length = 592
Score = 36.2 bits (82), Expect = 0.056
Identities = 15/41 (36%), Positives = 22/41 (53%)
Query: 363 CGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCR 403
C +C E + E + + C+H FH +CLQ +CP CR
Sbjct: 264 CTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCR 304
>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 36.2 bits (82), Expect = 0.056
Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 5/37 (13%)
Query: 378 QALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 409
+ LPC H F RCLQN + T SCP CR++S+ P
Sbjct: 33 KVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILP 69
>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 36.2 bits (82), Expect = 0.056
Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 5/37 (13%)
Query: 378 QALPCSHIFHLRCLQN-----NGTRSCPNCRRSSMKP 409
+ LPC H F RCLQN + T SCP CR++S+ P
Sbjct: 33 KVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILP 69
>gi|7706039 ring finger protein 181 [Homo sapiens]
Length = 153
Score = 36.2 bits (82), Expect = 0.056
Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 358 ETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCR 403
+ EL C +C E+ + ++ +PC H+FH C+ + T SCP CR
Sbjct: 71 QAELKCPVCLLEFEEEETAIE-MPCHHLFHSSCILPWLSKTNSCPLCR 117
>gi|27436927 synoviolin 1 isoform b [Homo sapiens]
Length = 617
Score = 35.8 bits (81), Expect = 0.073
Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 363 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMK 408
C +C E E + + LPC+HIFH CL++ ++CP CR ++
Sbjct: 291 CIICRE---EMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLR 335
>gi|27436925 synoviolin 1 isoform a [Homo sapiens]
Length = 616
Score = 35.8 bits (81), Expect = 0.073
Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 363 CGLCGESIGEKNSRLQALPCSHIFHLRCLQN--NGTRSCPNCRRSSMK 408
C +C E E + + LPC+HIFH CL++ ++CP CR ++
Sbjct: 291 CIICRE---EMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLR 335
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 35.8 bits (81), Expect = 0.073
Identities = 40/186 (21%), Positives = 70/186 (37%), Gaps = 36/186 (19%)
Query: 3 QDQTKQQIEKGLQLYQSNQTEKALQVWTKVLE--KSSDLMGRFRVLGCLV---------- 50
+DQ K+ I KG + Q ++ W ++ + + +D+ G G
Sbjct: 389 EDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDIQGALSAYGTATRILQEKVQAD 448
Query: 51 ----------TAHSEMGRYKEMLKFAVVQIDTARELEDAD------FLLESYLNLARSNE 94
H +G E K+ + +D A+ + D + + NLAR E
Sbjct: 449 VPPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYE 508
Query: 95 KLCEFHKTISYCKTCLGLPGTRAGAQLG-GQVSLSMGNAFLGLSVFQKALESFEKALRYA 153
+CEFH+ K L L G ++ GN F +A + F++AL+
Sbjct: 509 AMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGN-------FYEASDWFKEALQIN 561
Query: 154 HNNDDA 159
++ DA
Sbjct: 562 QDHPDA 567
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.135 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,331,759
Number of Sequences: 37866
Number of extensions: 573064
Number of successful extensions: 2116
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 1989
Number of HSP's gapped (non-prelim): 161
length of query: 412
length of database: 18,247,518
effective HSP length: 105
effective length of query: 307
effective length of database: 14,271,588
effective search space: 4381377516
effective search space used: 4381377516
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.