Search of human proteins with 156151445

Search of human proteins with 156151445

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
         (615 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]      1240   0.0  
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho...   125   1e-28
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H...   124   2e-28
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom...   124   3e-28
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H...   117   3e-26
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]       114   3e-25
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]       114   3e-25
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H...   113   6e-25
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [...   112   1e-24
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [...   112   1e-24
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC...   107   4e-23
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC...   107   4e-23
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s...   101   2e-21
gi|13236579 solute carrier family 27 member 3 [Homo sapiens]           85   2e-16
gi|38524616 solute carrier family 27, member 1 [Homo sapiens]          82   1e-15
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]     82   1e-15
gi|13325057 solute carrier family 27 (fatty acid transporter), m...    81   3e-15
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo...    80   7e-15
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo...    80   7e-15
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo...    80   7e-15
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo...    80   7e-15
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo...    79   9e-15
gi|40807357 solute carrier family 27 (fatty acid transporter), m...    77   4e-14
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho...    77   5e-14
gi|27477105 lipidosin [Homo sapiens]                                   75   1e-13
gi|227499619 solute carrier family 27 (fatty acid transporter), ...    72   1e-12
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom...    69   2e-11
gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens]                  65   1e-10
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo...    65   2e-10
gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo...    63   9e-10

>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
          Length = 615

 Score = 1240 bits (3209), Expect = 0.0
 Identities = 615/615 (100%), Positives = 615/615 (100%)

Query: 1   MAVYVGMLRLGRLCAGSSGVLGARAALSRSWQEARLQGVRFLSSREVDRMVSTPIGGLSY 60
           MAVYVGMLRLGRLCAGSSGVLGARAALSRSWQEARLQGVRFLSSREVDRMVSTPIGGLSY
Sbjct: 1   MAVYVGMLRLGRLCAGSSGVLGARAALSRSWQEARLQGVRFLSSREVDRMVSTPIGGLSY 60

Query: 61  VQGCTKKHLNSKTVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIG 120
           VQGCTKKHLNSKTVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIG
Sbjct: 61  VQGCTKKHLNSKTVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIG 120

Query: 121 LCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQ 180
           LCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQ
Sbjct: 121 LCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQ 180

Query: 181 FKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQ 240
           FKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQ
Sbjct: 181 FKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQ 240

Query: 241 HLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQ 300
           HLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQ
Sbjct: 241 HLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQ 300

Query: 301 LRMILPNPLYHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMF 360
           LRMILPNPLYHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMF
Sbjct: 301 LRMILPNPLYHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMF 360

Query: 361 VDILNQPDFSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAH 420
           VDILNQPDFSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAH
Sbjct: 361 VDILNQPDFSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAH 420

Query: 421 FPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEPQKTE 480
           FPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEPQKTE
Sbjct: 421 FPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEPQKTE 480

Query: 481 EAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQV 540
           EAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQV
Sbjct: 481 EAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQV 540

Query: 541 VGVKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKI 600
           VGVKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKI
Sbjct: 541 VGVKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKI 600

Query: 601 QKFKLREQMERHLNL 615
           QKFKLREQMERHLNL
Sbjct: 601 QKFKLREQMERHLNL 615


>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
           sapiens]
          Length = 579

 Score =  125 bits (313), Expect = 1e-28
 Identities = 135/526 (25%), Positives = 225/526 (42%), Gaps = 51/526 (9%)

Query: 97  DVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVN 155
           +++ +F +L ++  KAA+ L  + GL  GDR+ +  P    W L+ +A  + G +++   
Sbjct: 87  EIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGV 146

Query: 156 PAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTT 215
                 +L+Y L+    K+++       +   + +   CP ++               T 
Sbjct: 147 TQLTEKDLKYRLQASRAKSIITSDSLAPR--VDAISAECPSLQ---------------TK 189

Query: 216 VISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATL 275
           ++  D+  PG L   E++   ST       ++N       DP+ I FTSGTTG+PK    
Sbjct: 190 LLVSDSSRPGWLNFRELLREAST-------EHNCMRTKSRDPLAIYFTSGTTGAPKMVEH 242

Query: 276 SHYNIVNNSNILGER-LKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILAS- 333
           S  +        G R + L E        I  N         A T+       + I    
Sbjct: 243 SQSSYGLGFVASGRRWVALTESD------IFWNTTDTGWVKAAWTLFSAWPNGSCIFVHE 296

Query: 334 -PIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPELI 392
            P  + K  L  +S+   T L   PT+F  +L Q D + Y   ++   +  G    P++ 
Sbjct: 297 LPRVDAKVILNTLSKFPITTLCCVPTIF-RLLVQEDLTRYQFQSLRHCLTGGEALNPDVR 355

Query: 393 RAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTL 452
               ++  + +L   YG +E   V     P+  ++ K+ S+G+  P  + +I++ E   L
Sbjct: 356 EKWKHQTGV-ELYEGYGQSET--VVICANPKG-MKIKSGSMGKASPPYDVQIVDDEGNVL 411

Query: 453 AKLNTPGELCIR-----GYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVG 507
                 G + +R      +C    Y   P+KT  A +Q  +Y TGD A M++ G+   +G
Sbjct: 412 PP-GEEGNVAVRIRPTRPFCFFNCYLDNPEKTA-ASEQGDFYITGDRARMDKDGYFWFMG 469

Query: 508 RSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL-----KDGE 562
           R+ D+I      I P E+E     HP V E  VV   D   GE + A I L         
Sbjct: 470 RNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDP 529

Query: 563 ETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
           E    E++   K   + +K P+ + FV+  P T+SGKIQ+ KLR Q
Sbjct: 530 EALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQ 575


>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
           sapiens]
          Length = 580

 Score =  124 bits (312), Expect = 2e-28
 Identities = 143/527 (27%), Positives = 225/527 (42%), Gaps = 50/527 (9%)

Query: 96  EDVRLTFAQLKEEVDKAASGLLS-IGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154
           ++V+ +F +L     KAA+ L    GL +GDRL +  P    W L+ +A  + GII +  
Sbjct: 85  DEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPG 144

Query: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214
                A ++ Y L+    K +V              +++ P VE+           PDL 
Sbjct: 145 TIQLTAKDILYRLRASKAKCIV------------ASEEVAPAVESIV------LECPDLK 186

Query: 215 TVISVDAPL-PGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGA 273
           T + V      G L   E+    S      +           +P+ I FTSGTTG PK A
Sbjct: 187 TKLLVSPQSWNGWLSFQELFQFASEEHSCVET-------GSQEPMTIYFTSGTTGFPKMA 239

Query: 274 TLSHYNIVNNSNILGERLKLHEKTPEQL-RMILPNPLYHCLGSVAGTMMCLMYGATLILA 332
             S  ++     + G R  L  K+ + +  M     +   +GSV  + +C   GA + + 
Sbjct: 240 QHSQSSLGIGFTLCG-RYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLC---GACVFVH 295

Query: 333 SPI-FNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPEL 391
               F+    L+ ++    T L   PT++  +L Q D   Y   ++   +  G P  PE+
Sbjct: 296 RMAQFDTDTFLDTLTTYPITTLCSPPTVY-RMLVQKDLKRYKFKSLRHCLTGGEPLNPEV 354

Query: 392 IRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGT 451
           +     +  + +L   YG TE   V      +   E K  S+G+ M   + +I++ E G 
Sbjct: 355 LEQWRVQTGL-ELYEGYGQTE---VGMICANQKGQEIKPGSMGKGMLPYDVQIID-ENGN 409

Query: 452 LAKLNTPGELCIR-----GYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIV 506
           +      GE+ +R      +C    Y   PQKT   +  D +Y TGD   M+  G+   V
Sbjct: 410 VLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGD-FYVTGDRGVMDSDGYFWFV 468

Query: 507 GRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL-----KDG 561
           GR+ D+II  G  I P E+E     HP V E  VV   D   GE + A + L        
Sbjct: 469 GRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPFKSYN 528

Query: 562 EETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
            E    E++   K   + +K P+ + FV   P TI+GKI++  LR+Q
Sbjct: 529 PEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQ 575


>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
           sapiens]
          Length = 689

 Score =  124 bits (310), Expect = 3e-28
 Identities = 143/571 (25%), Positives = 240/571 (42%), Gaps = 74/571 (12%)

Query: 77  CLETTAQRVPEREALVVLHED----VRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGP 132
           CL+   ++ PE  AL+   ++    VR+T+ +L E   + A+ L   G+ +GDR+ ++ P
Sbjct: 114 CLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMP 173

Query: 133 NSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQ 192
            S   V   LA A+ G +   +   + A  L   +    CK ++   Q         LK+
Sbjct: 174 VSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKK 233

Query: 193 I-------CPEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQHLDQL 245
           I       CP V++     L + R  +   +  +D PL   +  ++ V A  +       
Sbjct: 234 IVDEAVKHCPTVQHV----LVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPES------- 282

Query: 246 QYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMIL 305
                 +   D + + +TSG+TG PKG   +    +  + +  + +  H+          
Sbjct: 283 ------MGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQ---------- 326

Query: 306 PNPLYHC---LGSVAGTMMC----LMYGATLIL--ASPIF-NGKKALEAISRERGTFLYG 355
           P  ++ C   +G + G        L  GAT +L  ++P++ N  +  E + R +    YG
Sbjct: 327 PGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYG 386

Query: 356 TPTMFVDILNQPD--FSSYDISTMCGGVIAGSPAPPELIRAIINKINMK--DLVVAYGTT 411
            PT    +L   D     YD S++      G P   E    +   +      LV  +  T
Sbjct: 387 APTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINCEAWEWLHRVVGDSRCTLVDTWWQT 446

Query: 412 ENSPVTFAHFPEDTVEQKAESVGRIMPHTEAR--------IMNMEAGTLAKLNTPGELCI 463
           E   +  A  P    E+ AE    I+P    R        +M+ +   +   N  G LCI
Sbjct: 447 ETGGICIAPRPS---EEGAE----ILPAMAMRPFFGIVPVLMDEKGSVVEGSNVSGALCI 499

Query: 464 RGYCVMLG--YWGEPQKTEEAVDQ--DKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGEN 519
                 +    +G+ Q+  +A  +    +Y+TGD A   E G+ +I GR  D+I   G  
Sbjct: 500 SQAWPGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHR 559

Query: 520 IYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRLKDG---EETTVEEIKAFCKGK 576
           +  AE+ED    HP V E  V+G   D  GE   A I +KD     +  V+E+K+    K
Sbjct: 560 LGTAEIEDAIADHPAVPESAVIGYPHDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATK 619

Query: 577 ISHFKIPKYIVFVTNYPLTISGKIQKFKLRE 607
           I+ + +P  I+ V   P T SGK+ +  LR+
Sbjct: 620 IAKYAVPDEILVVKRLPKTRSGKVMRRLLRK 650


>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
           sapiens]
          Length = 577

 Score =  117 bits (293), Expect = 3e-26
 Identities = 132/533 (24%), Positives = 236/533 (44%), Gaps = 62/533 (11%)

Query: 96  EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154
           ++V+ +F ++ +   + A+    + GL +GD L +  P    W L+ +   + GII +  
Sbjct: 82  DEVKWSFREMGDLTRRVANVFTQTCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPA 141

Query: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214
               +A ++ Y L+    K +V             +  +  EV++       + + P L 
Sbjct: 142 TILLKAKDILYRLQLSKAKGIV------------TIDALASEVDSI------ASQCPSLK 183

Query: 215 TVISV-DAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGA 273
           T + V D    G L    +V + S      + +         DP+ I FTSGTTG PK A
Sbjct: 184 TKLLVSDHSREGWLDFRSLVKSASPEHTCVKSK-------TLDPMVIFFTSGTTGFPKMA 236

Query: 274 TLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCL---GSVAGTMMCLMY----G 326
             SH          G  L+       +LR +  + +  CL   G +  T+  L+     G
Sbjct: 237 KHSH----------GLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVEPWTAG 286

Query: 327 ATLILAS-PIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGS 385
            T+ +   P F+ K  ++ + +      +G  +++  IL Q DF+S     +      G 
Sbjct: 287 CTVFIHHLPQFDTKVIIQTLLKYPINHFWGVSSIYRMILQQ-DFTSIRFPALEHCYTGGE 345

Query: 386 PAPPELIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIM 445
              P+       +  +  L   YG +E   +   ++    ++ K   +G+  P  + +++
Sbjct: 346 VVLPKDQEEWKRRTGLL-LYENYGQSETGLICATYWG---MKIKPGFMGKATPPYDVQVI 401

Query: 446 NMEAGTLAKLNTPGELCIR-----GYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQ 500
           + + G++   NT G + IR        + + Y G+P+KT + V+   +Y TGD   M+E+
Sbjct: 402 D-DKGSILPPNTEGNIGIRIKPVRPVSLFMCYEGDPEKTAK-VECGDFYNTGDRGKMDEE 459

Query: 501 GFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACI---- 556
           G+   +GRS D+I   G  I PAE+E     HP V E  VVG  D   GE + A I    
Sbjct: 460 GYICFLGRSDDIINASGYRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTP 519

Query: 557 -RLKDGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
             L   ++   +E++   K   + +K P+ + FV+  P TI+GKI++ +LR++
Sbjct: 520 QFLSHDKDQLTKELQQHVKSVTAPYKYPRKVEFVSELPKTITGKIERKELRKK 572


>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score =  114 bits (285), Expect = 3e-25
 Identities = 141/565 (24%), Positives = 232/565 (41%), Gaps = 88/565 (15%)

Query: 80  TTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKG-----DRLGMWGPNS 134
           T A    +R ALV  H   R T+ +L     + +  +  +  C G     +R+     N 
Sbjct: 48  TRALAFGDRIALVDQHG--RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCAND 105

Query: 135 YAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQIC 194
            ++V+ Q A+  +G + V +   + A +LEYV+       ++      +Q+Y  +L  + 
Sbjct: 106 ASYVVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVL-----ASQEYLELLSPV- 159

Query: 195 PEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSC 254
                                V  +  PL   L L   +  G+  +  +     Q + + 
Sbjct: 160 ---------------------VRKLGVPL---LPLTPAIYTGAVEEPAEVPVPEQGWRN- 194

Query: 255 HDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLG 314
                I +TSGTTG PKG   +H NI   + + G   K      + +  +LP  L+H  G
Sbjct: 195 -KGAMIIYTSGTTGRPKGVLSTHQNI--RAVVTGLVHKWAWTKDDVILHVLP--LHHVHG 249

Query: 315 SVAGTMMCLMYGATLILASPIFNGKKALEA-ISRE--RGTFLYGTPTMFVDILN------ 365
            V   +  L  GAT ++  P F+ ++  E  +S E  R       PT++  ++       
Sbjct: 250 VVNALLCPLWVGATCVMM-PEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHF 308

Query: 366 -QPDFSSYDISTMCGG----VIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAH 420
            QP    + +  +C      +++GS A P  +      I    L+  YG TE        
Sbjct: 309 TQPHAQDF-LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSG- 366

Query: 421 FPEDTVEQKAESVGRIMPHTEARIMNM----------------EAGTLAKLNTPG----- 459
            P  T  +   SVG  +P  + RI++                 E GT     TPG     
Sbjct: 367 -PLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKV---TPGFEEKE 422

Query: 460 -ELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGR-SKDMIIRGG 517
            EL +RG  V   YW +P++T+ A   D W+ TGD     + G   I GR S D+I  GG
Sbjct: 423 GELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKD-GQYWIRGRTSVDIIKTGG 481

Query: 518 ENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKI 577
             +   E+E     HP + +V V+GV D   G+ + A + L++G   +  E+K + +  +
Sbjct: 482 YKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNVL 541

Query: 578 SHFKIPKYIVFVTNYPLTISGKIQK 602
           + + +P  +V V   P    GKI K
Sbjct: 542 APYAVPSELVLVEEIPRNQMGKIDK 566


>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score =  114 bits (285), Expect = 3e-25
 Identities = 141/565 (24%), Positives = 232/565 (41%), Gaps = 88/565 (15%)

Query: 80  TTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKG-----DRLGMWGPNS 134
           T A    +R ALV  H   R T+ +L     + +  +  +  C G     +R+     N 
Sbjct: 48  TRALAFGDRIALVDQHG--RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCAND 105

Query: 135 YAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQIC 194
            ++V+ Q A+  +G + V +   + A +LEYV+       ++      +Q+Y  +L  + 
Sbjct: 106 ASYVVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVL-----ASQEYLELLSPV- 159

Query: 195 PEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSC 254
                                V  +  PL   L L   +  G+  +  +     Q + + 
Sbjct: 160 ---------------------VRKLGVPL---LPLTPAIYTGAVEEPAEVPVPEQGWRN- 194

Query: 255 HDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLG 314
                I +TSGTTG PKG   +H NI   + + G   K      + +  +LP  L+H  G
Sbjct: 195 -KGAMIIYTSGTTGRPKGVLSTHQNI--RAVVTGLVHKWAWTKDDVILHVLP--LHHVHG 249

Query: 315 SVAGTMMCLMYGATLILASPIFNGKKALEA-ISRE--RGTFLYGTPTMFVDILN------ 365
            V   +  L  GAT ++  P F+ ++  E  +S E  R       PT++  ++       
Sbjct: 250 VVNALLCPLWVGATCVMM-PEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHF 308

Query: 366 -QPDFSSYDISTMCGG----VIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAH 420
            QP    + +  +C      +++GS A P  +      I    L+  YG TE        
Sbjct: 309 TQPHAQDF-LRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSG- 366

Query: 421 FPEDTVEQKAESVGRIMPHTEARIMNM----------------EAGTLAKLNTPG----- 459
            P  T  +   SVG  +P  + RI++                 E GT     TPG     
Sbjct: 367 -PLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKV---TPGFEEKE 422

Query: 460 -ELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGR-SKDMIIRGG 517
            EL +RG  V   YW +P++T+ A   D W+ TGD     + G   I GR S D+I  GG
Sbjct: 423 GELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKD-GQYWIRGRTSVDIIKTGG 481

Query: 518 ENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRLKDGEETTVEEIKAFCKGKI 577
             +   E+E     HP + +V V+GV D   G+ + A + L++G   +  E+K + +  +
Sbjct: 482 YKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNVL 541

Query: 578 SHFKIPKYIVFVTNYPLTISGKIQK 602
           + + +P  +V V   P    GKI K
Sbjct: 542 APYAVPSELVLVEEIPRNQMGKIDK 566


>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
           sapiens]
          Length = 577

 Score =  113 bits (282), Expect = 6e-25
 Identities = 142/529 (26%), Positives = 229/529 (43%), Gaps = 55/529 (10%)

Query: 96  EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154
           +++   F +L E   +AA+ L  + GL +GDR+ +  P    W L+ L   +AG+I +  
Sbjct: 77  KELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPG 136

Query: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214
               ++ ++ Y L+    KA+V   +    Q  + +   CP           S R+  L 
Sbjct: 137 TIQMKSTDILYRLQMSKAKAIVAGDE--VIQEVDTVASECP-----------SLRIKLLV 183

Query: 215 TVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGAT 274
           +  S D  L    LL+E     ST  H   ++   Q  S      I FTSGT+G PK A 
Sbjct: 184 SEKSCDGWLNFKKLLNEA----STTHHC--VETGSQEASA-----IYFTSGTSGLPKMAE 232

Query: 275 LSHYNIVNNSNILGERLKLHEK-TPEQLRMIL--PNPLYHCLGSVAGTMMCLMYGA-TLI 330
            S+ +       LG + K+    T  Q   I+   +     L  +   M     GA T +
Sbjct: 233 HSYSS-------LGLKAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFV 285

Query: 331 LASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPE 390
              P F+    L+ +S      + G P ++  +L Q D SSY    +   V  G    PE
Sbjct: 286 HLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQ-DLSSYKFPHLQNCVTVGESLLPE 344

Query: 391 LIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAG 450
            +     +  + D+  +YG TE            T++ K   +G      + +I++ + G
Sbjct: 345 TLENWRAQTGL-DIRESYGQTETGLTCMV---SKTMKIKPGYMGTAASCYDVQIID-DKG 399

Query: 451 TLAKLNTPGELCIR-----GYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKI 505
            +    T G++ IR        +  GY   P KT   +  D W   GD    +E G+ + 
Sbjct: 400 NVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWL-LGDRGIKDEDGYFQF 458

Query: 506 VGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL------K 559
           +GR+ D+I   G  I P+E+E+    HP V E  V+   D   GE + A + L       
Sbjct: 459 MGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSH 518

Query: 560 DGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
           D E+ T +E++   K   + +K P+ I FV N P T++GKIQ+ KLR++
Sbjct: 519 DPEQLT-KELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDK 566


>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score =  112 bits (279), Expect = 1e-24
 Identities = 139/531 (26%), Positives = 230/531 (43%), Gaps = 59/531 (11%)

Query: 96  EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154
           +++   F +L E   +AA+ L  + GL +GDR+ +  P    W L+ L   +AG+I +  
Sbjct: 77  KELMWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPG 136

Query: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214
               ++ ++ Y L+    KA+V   +    Q  + +   CP           S R+  L 
Sbjct: 137 TIQMKSTDILYRLQMSKAKAIVAGDE--VIQEVDTVASECP-----------SLRIKLLV 183

Query: 215 TVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGAT 274
           +  S D  L    LL+E     ST  H   ++   Q  S      I FTSGT+G PK A 
Sbjct: 184 SEKSCDGWLNFKKLLNEA----STTHHC--VETGSQEASA-----IYFTSGTSGLPKMAE 232

Query: 275 LSHYNIVNNSNILGERLKLHEK-TPEQLRMIL-----PNPLYHCLGSVAGTMMCLMYGAT 328
            S+ +       LG + K+    T  Q   I+        + + LGS+  +    +   T
Sbjct: 233 HSYSS-------LGLKAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWT--LGACT 283

Query: 329 LILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAP 388
            +   P F+    L+ +S      + G P ++  +L Q D SSY    +   +  G    
Sbjct: 284 FVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQ-DLSSYKFPHLQNCLAGGESLL 342

Query: 389 PELIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNME 448
           PE +     +  + D+   YG TE            T++ K   +G      + ++++ +
Sbjct: 343 PETLENWRAQTGL-DIREFYGQTETGLTCMV---SKTMKIKPGYMGTAASCYDVQVID-D 397

Query: 449 AGTLAKLNTPGELCIR-----GYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFC 503
            G +    T G++ IR        +  GY   P KT   +  D W   GD    +E G+ 
Sbjct: 398 KGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDEDGYF 456

Query: 504 KIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL----- 558
           + +GR+ D+I   G  I P+E+E+    HP V E  V+   D   GE + A + L     
Sbjct: 457 QFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFL 516

Query: 559 -KDGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
             D E+ T +E++   K   + +K P+ I FV N P T++GKIQ+ KLR++
Sbjct: 517 SHDPEQLT-KELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDK 566


>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
           [Homo sapiens]
          Length = 577

 Score =  112 bits (279), Expect = 1e-24
 Identities = 139/531 (26%), Positives = 230/531 (43%), Gaps = 59/531 (11%)

Query: 96  EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154
           +++   F +L E   +AA+ L  + GL +GDR+ +  P    W L+ L   +AG+I +  
Sbjct: 77  KELMWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPG 136

Query: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214
               ++ ++ Y L+    KA+V   +    Q  + +   CP           S R+  L 
Sbjct: 137 TIQMKSTDILYRLQMSKAKAIVAGDE--VIQEVDTVASECP-----------SLRIKLLV 183

Query: 215 TVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGAT 274
           +  S D  L    LL+E     ST  H   ++   Q  S      I FTSGT+G PK A 
Sbjct: 184 SEKSCDGWLNFKKLLNEA----STTHHC--VETGSQEASA-----IYFTSGTSGLPKMAE 232

Query: 275 LSHYNIVNNSNILGERLKLHEK-TPEQLRMIL-----PNPLYHCLGSVAGTMMCLMYGAT 328
            S+ +       LG + K+    T  Q   I+        + + LGS+  +    +   T
Sbjct: 233 HSYSS-------LGLKAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWT--LGACT 283

Query: 329 LILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAP 388
            +   P F+    L+ +S      + G P ++  +L Q D SSY    +   +  G    
Sbjct: 284 FVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQ-DLSSYKFPHLQNCLAGGESLL 342

Query: 389 PELIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNME 448
           PE +     +  + D+   YG TE            T++ K   +G      + ++++ +
Sbjct: 343 PETLENWRAQTGL-DIREFYGQTETGLTCMV---SKTMKIKPGYMGTAASCYDVQVID-D 397

Query: 449 AGTLAKLNTPGELCIR-----GYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFC 503
            G +    T G++ IR        +  GY   P KT   +  D W   GD    +E G+ 
Sbjct: 398 KGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWL-LGDRGIKDEDGYF 456

Query: 504 KIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL----- 558
           + +GR+ D+I   G  I P+E+E+    HP V E  V+   D   GE + A + L     
Sbjct: 457 QFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFL 516

Query: 559 -KDGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
             D E+ T +E++   K   + +K P+ I FV N P T++GKIQ+ KLR++
Sbjct: 517 SHDPEQLT-KELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDK 566


>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 2 [Homo sapiens]
          Length = 571

 Score =  107 bits (266), Expect = 4e-23
 Identities = 137/528 (25%), Positives = 226/528 (42%), Gaps = 59/528 (11%)

Query: 96  EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154
           +++   F +L E   +AA+ L  + GL +GDR+ +  P    W L+ L   +AG+I +  
Sbjct: 77  KELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPG 136

Query: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214
               ++ ++ Y L+    KA+V   +    Q  + +   CP           S R+  L 
Sbjct: 137 TIQMKSTDILYRLQMSKAKAIVAGDE--VIQEVDTVASECP-----------SLRIKLLV 183

Query: 215 TVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGAT 274
           +  S D  L    LL+E     ST  H   ++   Q  S      I FTSGT+G PK A 
Sbjct: 184 SEKSCDGWLNFKKLLNEA----STTHHC--VETGSQEASA-----IYFTSGTSGLPKMAE 232

Query: 275 LSHYNIVNNSNILGERLKLHEK-TPEQLRMIL-----PNPLYHCLGSVAGTMMCLMYGAT 328
            S+ +       LG + K+    T  Q   I+        + + LGS+  +    +   T
Sbjct: 233 HSYSS-------LGLKAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWT--LGACT 283

Query: 329 LILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAP 388
            +   P F+    L+ +S      + G P ++  +L Q D SSY    +   +  G    
Sbjct: 284 FVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQ-DLSSYKFPHLQNCLAGGESLL 342

Query: 389 PELIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNME 448
           PE +     +  + D+   YG TE            T++ K   +G      + +++   
Sbjct: 343 PETLENWRAQTGL-DIREFYGQTETGLTCMV---SKTMKIKPGYMGTAASCYDVQVIAFV 398

Query: 449 AGTLAKLNTPGELCIRGYCVM--LGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIV 506
            G+       G+L   G   +   G+   P KT   +  D W   GD    +E G+ + +
Sbjct: 399 HGS----PRAGDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFM 453

Query: 507 GRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL------KD 560
           GR+ D+I   G  I P+E+E+    HP V E  V+   D   GE + A + L       D
Sbjct: 454 GRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHD 513

Query: 561 GEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
            E+ T +E++   K   + +K P+ I FV N P T++GKIQ+ KLR++
Sbjct: 514 PEQLT-KELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDK 560


>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
           ACSM2B, mitochondrial isoform 1 [Homo sapiens]
          Length = 571

 Score =  107 bits (266), Expect = 4e-23
 Identities = 137/528 (25%), Positives = 226/528 (42%), Gaps = 59/528 (11%)

Query: 96  EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154
           +++   F +L E   +AA+ L  + GL +GDR+ +  P    W L+ L   +AG+I +  
Sbjct: 77  KELMWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPG 136

Query: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214
               ++ ++ Y L+    KA+V   +    Q  + +   CP           S R+  L 
Sbjct: 137 TIQMKSTDILYRLQMSKAKAIVAGDE--VIQEVDTVASECP-----------SLRIKLLV 183

Query: 215 TVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGAT 274
           +  S D  L    LL+E     ST  H   ++   Q  S      I FTSGT+G PK A 
Sbjct: 184 SEKSCDGWLNFKKLLNEA----STTHHC--VETGSQEASA-----IYFTSGTSGLPKMAE 232

Query: 275 LSHYNIVNNSNILGERLKLHEK-TPEQLRMIL-----PNPLYHCLGSVAGTMMCLMYGAT 328
            S+ +       LG + K+    T  Q   I+        + + LGS+  +    +   T
Sbjct: 233 HSYSS-------LGLKAKMDAGWTGLQASDIMWTISDTGWILNILGSLLESWT--LGACT 283

Query: 329 LILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAP 388
            +   P F+    L+ +S      + G P ++  +L Q D SSY    +   +  G    
Sbjct: 284 FVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQ-DLSSYKFPHLQNCLAGGESLL 342

Query: 389 PELIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNME 448
           PE +     +  + D+   YG TE            T++ K   +G      + +++   
Sbjct: 343 PETLENWRAQTGL-DIREFYGQTETGLTCMV---SKTMKIKPGYMGTAASCYDVQVIAFV 398

Query: 449 AGTLAKLNTPGELCIRGYCVM--LGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIV 506
            G+       G+L   G   +   G+   P KT   +  D W   GD    +E G+ + +
Sbjct: 399 HGS----PRAGDLGFAGTMTLSFCGHQENPDKTAANIRGDFWL-LGDRGIKDEDGYFQFM 453

Query: 507 GRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL------KD 560
           GR+ D+I   G  I P+E+E+    HP V E  V+   D   GE + A + L       D
Sbjct: 454 GRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHD 513

Query: 561 GEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
            E+ T +E++   K   + +K P+ I FV N P T++GKIQ+ KLR++
Sbjct: 514 PEQLT-KELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDK 560


>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
           sapiens]
          Length = 586

 Score =  101 bits (251), Expect = 2e-21
 Identities = 124/525 (23%), Positives = 221/525 (42%), Gaps = 46/525 (8%)

Query: 96  EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154
           E++R +F +L     K A+ L  +  L +GDR+ +  P    W L  +A  + G +L+  
Sbjct: 91  EEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPG 150

Query: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214
                  ++ Y L+      ++             +  +  + EN     + S+   +  
Sbjct: 151 TTQLTQKDILYRLQSSKANCII-----TNDVLAPAVDAVASKCENLHSKLIVSENSRE-- 203

Query: 215 TVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGAT 274
                     G   L E++   S      + ++N+          I FTSGT+G PK   
Sbjct: 204 ----------GWGNLKELMKHASDSHTCVKTKHNEIMA-------IFFTSGTSGYPKMTA 246

Query: 275 LSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILAS- 333
            +H +     ++ G R  L + TP  + M   +       + +      + GA +     
Sbjct: 247 HTHSSFGLGLSVNG-RFWL-DLTPSDV-MWNTSDTGWAKSAWSSVFSPWIQGACVFTHHL 303

Query: 334 PIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPELIR 393
           P F     L+ +S+   T     PT++  +L Q D +SY   ++   V AG P  P++  
Sbjct: 304 PRFEPTSILQTLSKYPITVFCSAPTVY-RMLVQNDITSYKFKSLKHCVSAGEPITPDVTE 362

Query: 394 AIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLA 453
              NK  + D+   YG TE   +   +F    +  K  S+G+  P  + +I+++    L 
Sbjct: 363 KWRNKTGL-DIYEGYGQTETVLIC-GNFKGMKI--KPGSMGKPSPAFDVKIVDVNGNVLP 418

Query: 454 KLNTPGELCI-----RGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGR 508
                G++ I     R + +   Y   P KT   + +  +Y TGD   M++ G+   V R
Sbjct: 419 P-GQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTL-RGNFYITGDRGYMDKDGYFWFVAR 476

Query: 509 SKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL-----KDGEE 563
           + D+I+  G  I P E+E+  + HP V E  VV   D   GE + A + L        +E
Sbjct: 477 ADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQE 536

Query: 564 TTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
             ++EI+   K   + +K P+ + F+   P TISGK ++ +LR++
Sbjct: 537 QLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKK 581


>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
          Length = 730

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 116/522 (22%), Positives = 207/522 (39%), Gaps = 57/522 (10%)

Query: 112 AASGLLSIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVG 171
           A  G  +  L  G  + +  P    ++ +    A+AG+    V  A +   L + L+  G
Sbjct: 202 ARGGGAAAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCG 261

Query: 172 CKALVFPKQF--KTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVIS--VDAPLPGTL 227
            +ALV   +F    +     L+ +   +  A PG   +  + DL   +S  VD P+PG L
Sbjct: 262 ARALVLAPEFLESLEPDLPALRAMGLHLWAAGPGTHPAG-ISDLLAEVSAEVDGPVPGYL 320

Query: 228 LLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNIL 287
              + +                      D     FTSGTTG PK A +SH  I+      
Sbjct: 321 SSPQSIT---------------------DTCLYIFTSGTTGLPKAARISHLKILQCQGFY 359

Query: 288 GERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISR 347
            +   +H++    L +    PLYH  GS+ G + C+  GAT++L S  F+  +  E   +
Sbjct: 360 -QLCGVHQEDVIYLAL----PLYHMSGSLLGIVGCMGIGATVVLKSK-FSAGQFWEDCQQ 413

Query: 348 ERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVA 407
            R T       +   ++NQP   +     +   +  GS   P+     + +     ++  
Sbjct: 414 HRVTVFQYIGELCRYLVNQPPSKAERGHKV--RLAVGSGLRPDTWERFVRRFGPLQVLET 471

Query: 408 YGTTENSPVTFAHFPEDTVEQKAESVGR-IMPHTEAR--------IMNMEAGTLAKLNTP 458
           YG TE +  T  +  +     +A  + + I P +  R        I + +   +A   +P
Sbjct: 472 YGLTEGNVATINYTGQRGAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMA--TSP 529

Query: 459 GE-----LCIRGYCVMLGYWGEPQKTEEAVDQDKW------YWTGDVATMNEQGFCKIVG 507
           GE       +      LGY G P+  +  + +D +      + TGD+   ++QGF +   
Sbjct: 530 GEPGLLVAPVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHD 589

Query: 508 RSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVK-DDRMGEEICACIRLKDGEETTV 566
           R+ D     GEN+   E+ + F     +QEV V GV      G    A + L+      +
Sbjct: 590 RTGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALDL 649

Query: 567 EEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
            ++       +  +  P+++    +   T + K QK ++  +
Sbjct: 650 MQLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMANE 691


>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
          Length = 646

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 120/498 (24%), Positives = 193/498 (38%), Gaps = 59/498 (11%)

Query: 73  TVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGP 132
           T+ +  +   QR PER ALV        TFAQL    +  A+    +G   GD + ++  
Sbjct: 77  TIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGFAPGDVVAIFLE 136

Query: 133 NSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQ 192
               +V + L  A+AG+    +N   +   L + L   G KAL+F  +         +  
Sbjct: 137 GRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGE---------MVA 187

Query: 193 ICPEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFL 252
              EV     G L    +   +  +  +  LP T LLD ++   ST   L Q+       
Sbjct: 188 AVAEVS----GHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAP-LAQIPSK---- 238

Query: 253 SCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHC 312
              D +   +TSGTTG PK A + H      +       ++  +  + L   L  PLYH 
Sbjct: 239 GMDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRM--QAADVLYDCL--PLYHS 294

Query: 313 LGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSY 372
            G++ G   CL+YG T++L    F+  +  +   +   T +     +   +L QP   + 
Sbjct: 295 AGNIIGVGQCLIYGLTVVLRKK-FSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAE 353

Query: 373 DISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTE-NSPVTFAHFPEDTVEQKAE 431
               +   +  G+   P +      +  ++ +   YG TE N  +         ++ K  
Sbjct: 354 RRHRV--RLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIA-------NMDGKVG 404

Query: 432 SVG---RIMPHT-EARIMNMEAGTLAKLNTPGELCI---RGYCVML-------------- 470
           S G   RI+PH    R++ +   T+  L     LCI    G   +L              
Sbjct: 405 SCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFD 464

Query: 471 GYWGEPQKTEEAVDQ-----DKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAEL 525
           GY  E   +++         D  Y +GDV  M+E G+     RS D     GEN+   E+
Sbjct: 465 GYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEV 524

Query: 526 EDFFHTHPKVQEVQVVGV 543
           E          +V V GV
Sbjct: 525 EGVLSRLLGQTDVAVYGV 542


>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
          Length = 666

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 114/505 (22%), Positives = 187/505 (37%), Gaps = 96/505 (19%)

Query: 100 LTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQ 159
           L F Q  E   KAA  L+ +GL +   +G+ G NS  W +  +    AG + V +     
Sbjct: 81  LNFNQYYEACRKAAKSLIKLGLERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATNS 140

Query: 160 AMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVISV 219
           A   +YV+       L+       QQ   +L             ++    L  L  +I  
Sbjct: 141 AEVCQYVITHAKVNILLVEND---QQLQKIL-------------SIPQSSLEPLKAIIQY 184

Query: 220 DAPLPGTLLL---DEVVAAGST--RQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGAT 274
             P+     L   D+ +  G +     L+Q+  +Q+   C   I   +TSGTTG PKG  
Sbjct: 185 RLPMKKNNNLYSWDDFMELGRSIPDTQLEQVIESQKANQCAVLI---YTSGTTGIPKGVM 241

Query: 275 LSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILASP 334
           LSH NI   +  + +  KL +K    +  +   PL H    +    + +  GA    A  
Sbjct: 242 LSHDNITWIAGAVTKDFKLTDKHETVVSYL---PLSHIAAQMMDIWVPIKIGALTYFAQA 298

Query: 335 IFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPELIRA 394
                  +  +   + T   G P ++  I      +S     +       +       R 
Sbjct: 299 DALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWA-------RN 351

Query: 395 IINKINMKDLVVAYGTTENSPVTF---------------------------AHFPEDTVE 427
           I  K+N K ++  Y    N+PV++                           A   ++T E
Sbjct: 352 IGFKVNSKKMLGKY----NTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAE 407

Query: 428 -------------QKAESVGRIMPHTEARIMNMEAGTLAKLNTP-------------GEL 461
                          +ES G   PHT +   N    +  K+ T              GE+
Sbjct: 408 FFLSLDIPIGELYGLSESSG---PHTISNQNNYRLLSCGKILTGCKNMLFQQNKDGIGEI 464

Query: 462 CIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMII-RGGENI 520
           C+ G  + +GY     +T EA+D + W  +GD+  ++  GF  + G  K+++I  GGEN+
Sbjct: 465 CLWGRHIFMGYLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENV 524

Query: 521 YPAELEDFFHTH-PKVQEVQVVGVK 544
            P  +E       P +    +VG K
Sbjct: 525 PPIPVETLVKKKIPIISNAMLVGDK 549


>gi|13325057 solute carrier family 27 (fatty acid transporter),
           member 5 [Homo sapiens]
          Length = 690

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 145/637 (22%), Positives = 245/637 (38%), Gaps = 66/637 (10%)

Query: 3   VYVGMLRLGRLCAGS---SGVLGARAALSRSWQEARLQ-GVRFLSSREVDRMVSTPIGGL 58
           V +G+  L R   G     G+  A AAL+ +   ARL  G+R+L +  +       +G  
Sbjct: 44  VLLGLAMLARPWLGPWVPHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHLG-- 101

Query: 59  SYVQGCTKKHLNSKTVGQCLETTAQRVPEREALVVLHEDV-RLTFAQLKEEVDKAASGLL 117
             ++GC  +     T     E  A+  P R  LV        +TF +L     +AA  L 
Sbjct: 102 LKIRGCLSRQ-PPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALK 160

Query: 118 S-----IGLCKGDRLGMWGPNSYAW--VLMQLATAQAGIILVSVNPAYQAMELEYVLKKV 170
           +       LC G+   +    S A   + M L  A+ G     +NP  + M L + +   
Sbjct: 161 AELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLSS 220

Query: 171 GCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLD 230
           G + LV     +       L++I P+++                  +S  +P PG   L 
Sbjct: 221 GARVLVVDPDLRES-----LEEILPKLQAENIRCF----------YLSHTSPTPGVGALG 265

Query: 231 EVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGER 290
             + A  +      L+     ++   P    +TSGTTG PK A L+H  ++  S +L   
Sbjct: 266 AALDAAPSHPVPADLRAG---ITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLS-- 320

Query: 291 LKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERG 350
             L   T + + +    PLYH +G V G + CL  GAT +LA P F+     +   +   
Sbjct: 321 --LSGATADDV-VYTVLPLYHVMGLVVGILGCLDLGATCVLA-PKFSTSCFWDDCRQHGV 376

Query: 351 TFLYGTPTM---FVDILNQPDFSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVA 407
           T +     +     +I  QP+  ++ +    G  +       ++      +     +   
Sbjct: 377 TVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRA-----DVWETFQQRFGPIRIWEV 431

Query: 408 YGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAK----------LNT 457
           YG+TE +     +        K   + R++   E    +MEA    +          L  
Sbjct: 432 YGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGE 491

Query: 458 PGELCIR--GYCVMLGYWGEPQKTEEAV------DQDKWYWTGDVATMNEQGFCKIVGRS 509
           PG L  +       +GY G  + +E  +        D +Y TGDV  M+ +GF     R 
Sbjct: 492 PGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRL 551

Query: 510 KDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGV-KDDRMGEEICACIRLKDGEETTVEE 568
            D     GEN+   E+E        +Q+V V GV      G+   A ++L  G+    E+
Sbjct: 552 GDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEK 611

Query: 569 IKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKL 605
           +    +  +  +  P +I       +T + K+ K +L
Sbjct: 612 LYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRL 648


>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score = 79.7 bits (195), Expect = 7e-15
 Identities = 112/487 (22%), Positives = 195/487 (40%), Gaps = 61/487 (12%)

Query: 100 LTFAQLKEEVDKAASGLLSIGLCKGDR--LGMWGPNSYAWVLMQLATAQAGIILVSVNPA 157
           L++ Q+ +  +   S LL  G        +G++  N   W++ +LA     ++ V   P 
Sbjct: 106 LSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAV---PL 162

Query: 158 YQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVI 217
           Y  +  E ++  V  KA +      T Q   VL      + N + G   S ++  L    
Sbjct: 163 YDTLGPEAIVHIVN-KADIAMVICDTPQKALVL------IGNVEKGFTPSLKVIILMDPF 215

Query: 218 SVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPIN-IQFTSGTTGSPKGATLS 276
             D    G     E+++     ++L +  + +      + ++ I FTSGTTG PKGA ++
Sbjct: 216 DDDLKQRGEKSGIEILSLYDA-ENLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMIT 274

Query: 277 HYNIVNNSNILGERLK-LHEKTPEQLRMILPNPLYHCLGSVA-------GTMMCLMYGAT 328
           H NIV+N+    + ++  +E TP+ +  I   PL H    +        G  +    G  
Sbjct: 275 HQNIVSNAAAFLKCVEHAYEPTPDDVA-ISYLPLAHMFERIVQAVVYSCGARVGFFQGDI 333

Query: 329 LILASPIFNGKKAL------------EAISRERGTFL------YGTPTMFVDILNQPDFS 370
            +LA  +   K  L            + +  E  T L          + F ++  Q    
Sbjct: 334 RLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKFLLKLAVSSKFKEL--QKGII 391

Query: 371 SYD----------ISTMCGG----VIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPV 416
            +D          I    GG    ++ G+      +           +  AYG TE +  
Sbjct: 392 RHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGG 451

Query: 417 TFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEP 476
                P D     +  VG  +     ++ ++       +N  GE+CI+G  V  GY  +P
Sbjct: 452 CTFTLPGDWT---SGHVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDP 508

Query: 477 QKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMI-IRGGENIYPAELEDFFHTHPKV 535
           +KT+EA+D D W  TGD+      G  KI+ R K++  +  GE I P ++E+ ++    V
Sbjct: 509 EKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPV 568

Query: 536 QEVQVVG 542
            ++ V G
Sbjct: 569 LQIFVHG 575


>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
           b [Homo sapiens]
          Length = 683

 Score = 79.7 bits (195), Expect = 7e-15
 Identities = 112/487 (22%), Positives = 195/487 (40%), Gaps = 61/487 (12%)

Query: 100 LTFAQLKEEVDKAASGLLSIGLCKGDR--LGMWGPNSYAWVLMQLATAQAGIILVSVNPA 157
           L++ Q+ +  +   S LL  G        +G++  N   W++ +LA     ++ V   P 
Sbjct: 106 LSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAV---PL 162

Query: 158 YQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVI 217
           Y  +  E ++  V  KA +      T Q   VL      + N + G   S ++  L    
Sbjct: 163 YDTLGPEAIVHIVN-KADIAMVICDTPQKALVL------IGNVEKGFTPSLKVIILMDPF 215

Query: 218 SVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPIN-IQFTSGTTGSPKGATLS 276
             D    G     E+++     ++L +  + +      + ++ I FTSGTTG PKGA ++
Sbjct: 216 DDDLKQRGEKSGIEILSLYDA-ENLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMIT 274

Query: 277 HYNIVNNSNILGERLK-LHEKTPEQLRMILPNPLYHCLGSVA-------GTMMCLMYGAT 328
           H NIV+N+    + ++  +E TP+ +  I   PL H    +        G  +    G  
Sbjct: 275 HQNIVSNAAAFLKCVEHAYEPTPDDVA-ISYLPLAHMFERIVQAVVYSCGARVGFFQGDI 333

Query: 329 LILASPIFNGKKAL------------EAISRERGTFL------YGTPTMFVDILNQPDFS 370
            +LA  +   K  L            + +  E  T L          + F ++  Q    
Sbjct: 334 RLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKFLLKLAVSSKFKEL--QKGII 391

Query: 371 SYD----------ISTMCGG----VIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPV 416
            +D          I    GG    ++ G+      +           +  AYG TE +  
Sbjct: 392 RHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGG 451

Query: 417 TFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEP 476
                P D     +  VG  +     ++ ++       +N  GE+CI+G  V  GY  +P
Sbjct: 452 CTFTLPGDWT---SGHVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDP 508

Query: 477 QKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMI-IRGGENIYPAELEDFFHTHPKV 535
           +KT+EA+D D W  TGD+      G  KI+ R K++  +  GE I P ++E+ ++    V
Sbjct: 509 EKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPV 568

Query: 536 QEVQVVG 542
            ++ V G
Sbjct: 569 LQIFVHG 575


>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
           a [Homo sapiens]
          Length = 739

 Score = 79.7 bits (195), Expect = 7e-15
 Identities = 112/487 (22%), Positives = 195/487 (40%), Gaps = 61/487 (12%)

Query: 100 LTFAQLKEEVDKAASGLLSIGLCKGDR--LGMWGPNSYAWVLMQLATAQAGIILVSVNPA 157
           L++ Q+ +  +   S LL  G        +G++  N   W++ +LA     ++ V   P 
Sbjct: 162 LSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAV---PL 218

Query: 158 YQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVI 217
           Y  +  E ++  V  KA +      T Q   VL      + N + G   S ++  L    
Sbjct: 219 YDTLGPEAIVHIVN-KADIAMVICDTPQKALVL------IGNVEKGFTPSLKVIILMDPF 271

Query: 218 SVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPIN-IQFTSGTTGSPKGATLS 276
             D    G     E+++     ++L +  + +      + ++ I FTSGTTG PKGA ++
Sbjct: 272 DDDLKQRGEKSGIEILSLYDA-ENLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMIT 330

Query: 277 HYNIVNNSNILGERLK-LHEKTPEQLRMILPNPLYHCLGSVA-------GTMMCLMYGAT 328
           H NIV+N+    + ++  +E TP+ +  I   PL H    +        G  +    G  
Sbjct: 331 HQNIVSNAAAFLKCVEHAYEPTPDDVA-ISYLPLAHMFERIVQAVVYSCGARVGFFQGDI 389

Query: 329 LILASPIFNGKKAL------------EAISRERGTFL------YGTPTMFVDILNQPDFS 370
            +LA  +   K  L            + +  E  T L          + F ++  Q    
Sbjct: 390 RLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKFLLKLAVSSKFKEL--QKGII 447

Query: 371 SYD----------ISTMCGG----VIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPV 416
            +D          I    GG    ++ G+      +           +  AYG TE +  
Sbjct: 448 RHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGG 507

Query: 417 TFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEP 476
                P D     +  VG  +     ++ ++       +N  GE+CI+G  V  GY  +P
Sbjct: 508 CTFTLPGDWT---SGHVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDP 564

Query: 477 QKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMI-IRGGENIYPAELEDFFHTHPKV 535
           +KT+EA+D D W  TGD+      G  KI+ R K++  +  GE I P ++E+ ++    V
Sbjct: 565 EKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPV 624

Query: 536 QEVQVVG 542
            ++ V G
Sbjct: 625 LQIFVHG 631


>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
           b [Homo sapiens]
          Length = 722

 Score = 79.7 bits (195), Expect = 7e-15
 Identities = 111/488 (22%), Positives = 191/488 (39%), Gaps = 63/488 (12%)

Query: 100 LTFAQLKEEVDKAASGLL--SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPA 157
           L++ ++ +  +   SGLL  +   C    +G++  N   W++++LA     +++V +   
Sbjct: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205

Query: 158 YQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVI 217
                + Y++       ++  K  K      VL  +   VE  +   LK   L D     
Sbjct: 206 LGPGAIRYIINTADISTVIVDKPQKA-----VL--LLEHVERKETPGLKLIILMDPFEEA 258

Query: 218 SVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQ-FTSGTTGSPKGATLS 276
             +      +++  + A     Q   Q     Q     D ++I  FTSGTTG+PKGA L+
Sbjct: 259 LKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ----PDDLSIVCFTSGTTGNPKGAMLT 314

Query: 277 HYNIVNNSNILGERLKLHEKT--PEQLRMILP-NPLYHCLGSVAGTMMCLMYGATLILAS 333
           H N+V +       LK+ EK   P Q  +++   PL H    V  +++    G       
Sbjct: 315 HGNVVAD---FSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQG 371

Query: 334 PI---FNGKKAL----------------EAISRERGTFLYGTPTMFVDILNQPDFSS--- 371
            I    +  KAL                + I  +  T L      F     Q +  S   
Sbjct: 372 DIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGII 431

Query: 372 -----------YDISTMCGGVI-----AGSPAPPELIRAIINKINMKDLVVAYGTTENSP 415
                        I    GG +       +PA P ++  +   +  + +   YG TE + 
Sbjct: 432 RNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQ-VYEGYGQTECTA 490

Query: 416 VTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGE 475
                 P D     +  VG  +P    +++++E          GE+C+RG  V  GY  +
Sbjct: 491 GCTFTTPGDWT---SGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKD 547

Query: 476 PQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMI-IRGGENIYPAELEDFFHTHPK 534
           P +T+EA+D D W  TGD+      G  KI+ R K +  +  GE + P ++E+ +     
Sbjct: 548 PDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQP 607

Query: 535 VQEVQVVG 542
           V ++ V G
Sbjct: 608 VAQIYVHG 615


>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
           sapiens]
          Length = 698

 Score = 79.3 bits (194), Expect = 9e-15
 Identities = 108/491 (21%), Positives = 190/491 (38%), Gaps = 69/491 (14%)

Query: 100 LTFAQLKEEVDKAASGLLSIGL--CKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPA 157
           L++ Q+ E  +   S L+  G        +G++  N   WV+++       +++V +   
Sbjct: 121 LSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDT 180

Query: 158 YQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVI 217
                + Y++ K     +   K  K        K +   VEN        + +P L  ++
Sbjct: 181 LGNEAITYIVNKAELSLVFVDKPEKA-------KLLLEGVEN--------KLIPGLKIIV 225

Query: 218 SVDAPLPGTLLLDEVVAAG----STRQHLDQLQYNQQFLSCHDPINIQ---FTSGTTGSP 270
            +DA   G+ L++     G    S +   D  + N++      P ++    FTSGTTG+P
Sbjct: 226 VMDAY--GSELVERGQRCGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNP 283

Query: 271 KGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATL- 329
           KGA ++H NIV++ +   +  +          +I   PL H    V   +M L +GA + 
Sbjct: 284 KGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFLPLAHMFERVVECVM-LCHGAKIG 342

Query: 330 --------------ILASPIFNG-----KKALEAISRERGTFLYGTPTMFVDILNQPDFS 370
                         +L   +F        +  + I  +  T L      F     + +  
Sbjct: 343 FFQGDIRLLMDDLKVLQPTVFPVVPRLLNRMFDRIFGQANTTLKRWLLDFASKRKEAELR 402

Query: 371 S--------------YDISTMCGG----VIAGSPAPPELIRAIINKINMKDLVVAYGTTE 412
           S              + + +  GG    ++ G+      +   +           YG TE
Sbjct: 403 SGIIRNNSLWDRLIFHKVQSSLGGRVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTE 462

Query: 413 NSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVMLGY 472
            +       P D     A  VG  MP    +++++E          GE+C++G  V  GY
Sbjct: 463 CTAGCCLTMPGDWT---AGHVGAPMPCNLIKLVDVEEMNYMAAEGEGEVCVKGPNVFQGY 519

Query: 473 WGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMI-IRGGENIYPAELEDFFHT 531
             +P KT EA+D+D W  TGD+      G  KI+ R K +  +  GE I P ++E+ +  
Sbjct: 520 LKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMR 579

Query: 532 HPKVQEVQVVG 542
              V +V V G
Sbjct: 580 SEPVAQVFVHG 590


>gi|40807357 solute carrier family 27 (fatty acid transporter),
           member 4 [Homo sapiens]
          Length = 643

 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 121/563 (21%), Positives = 223/563 (39%), Gaps = 58/563 (10%)

Query: 72  KTVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWG 131
           +TV     +T +R P++ AL+    D   TF QL E     A+ L + GL  GD   ++ 
Sbjct: 74  RTVPILFASTVRRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQARGLASGDVAAIFM 133

Query: 132 PNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLK 191
            N   +V + L  A+ G+    +N   +   L + L     +ALVF  +        V  
Sbjct: 134 ENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFGSEM-ASAICEVHA 192

Query: 192 QICPEVENAQPGALKSQRLPDLTTVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQF 251
            + P +     G+ +   +P            P T  LD ++      +HL     ++ F
Sbjct: 193 SLDPSLSLFCSGSWEPGAVP------------PSTEHLDPLLK--DAPKHLPSCP-DKGF 237

Query: 252 LSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNIL--GERLKLHEKTPEQLRMILPNPL 309
               D +   +TSGTTG PK A + H      + ++  G R++ ++   + L      PL
Sbjct: 238 T---DKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCL------PL 288

Query: 310 YHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDF 369
           YH  G++ G   CL++G T+++    F+  +  +   +   T +     +   +LNQP  
Sbjct: 289 YHSAGNIVGIGQCLLHGMTVVIRKK-FSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPR 347

Query: 370 SSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQK 429
            + +   +   +  G+     +     ++ ++  +   YG TE +  +  +F  D+    
Sbjct: 348 EAENQHQV--RMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECN-CSLGNF--DSQVGA 402

Query: 430 AESVGRIMPHT-EARIMNMEAGTLAKLNTPGELCI--------------------RGYCV 468
                RI+      R++ +   T+  +  P  +CI                    R +  
Sbjct: 403 CGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDG 462

Query: 469 MLGYWGEPQKTEEAVDQ--DKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELE 526
            L      +K  + V +  D+ Y TGDV  M+E G+     R+ D     GEN+   E+E
Sbjct: 463 YLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVE 522

Query: 527 DFFHTHPKVQEVQVVGVK-DDRMGEEICACIRLKDGEETTVEEIKAFCKGKISHFKIPKY 585
                   + +V V GV+     G    A +    G    +E      + ++  +  P +
Sbjct: 523 GTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTG-NCDLERFAQVLEKELPLYARPIF 581

Query: 586 IVFVTNYPLTISGKIQKFKLREQ 608
           +  +     T + K QK +LR++
Sbjct: 582 LRLLPELHKTGTYKFQKTELRKE 604


>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
           sapiens]
          Length = 480

 Score = 77.0 bits (188), Expect = 5e-14
 Identities = 109/439 (24%), Positives = 175/439 (39%), Gaps = 54/439 (12%)

Query: 96  EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154
           E+ + +F ++ +   KAAS L  +  L  GDRL +  P +     + LA  + GI  V  
Sbjct: 82  EEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPG 141

Query: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214
           +P   A ++ Y L+    + +V              + + P V +A          P L 
Sbjct: 142 SPQLTAKKIRYQLRMSKAQCIV------------ANEAMAPVVNSAVSDC------PTLK 183

Query: 215 TVISV-DAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGA 273
           T + V D    G L   +++     +Q   + +         DP+ I FT GTTG+PK  
Sbjct: 184 TKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTK-------SQDPMAIFFTKGTTGAPKMV 236

Query: 274 TLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILAS 333
             S Y +    +    R    +  P  +   L +     L S++  +     GA + L  
Sbjct: 237 EYSQYGLGMGFSQASRRWM--DLQPTDVLWSLGDAFGGSL-SLSAVLGTWFQGACVFLCH 293

Query: 334 -PIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPELI 392
            P F  +  L  +SR   T L   P M+ ++L    F+SY   ++   V AG P  P +I
Sbjct: 294 MPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISPGVI 353

Query: 393 RAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNM----- 447
                +I   D+   YG TE   +        T++ K  S+G+ +P    +I++      
Sbjct: 354 ED-WKRITKLDIYEGYGQTETGLLCAT---SKTIKLKPSSLGKPLPPYIVQIVDENSNLL 409

Query: 448 ---EAGTLA---KLNTPGELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQG 501
              E G +A   KLN P  L    YC  +  W E       +     Y TGD   M+E G
Sbjct: 410 PPGEEGNIAIRIKLNQPASL----YCPHMVSWEEYASARGHM----LYLTGDRGIMDEDG 461

Query: 502 FCKIVGRSKDMIIRGGENI 520
           +    GR  D+    G+ +
Sbjct: 462 YFWWSGRVDDVANALGQRL 480


>gi|27477105 lipidosin [Homo sapiens]
          Length = 724

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 41/125 (32%), Positives = 65/125 (52%), Gaps = 10/125 (8%)

Query: 404 LVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCI 463
           L   YG +E S     HF       +  S G+++P    +++N +A  +      GE+C+
Sbjct: 470 LYAGYGLSETSG---PHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGI------GEICL 520

Query: 464 RGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGRSKDMII-RGGENIYP 522
            G  + +GY     KT EA+D++ W  TGD   ++  GF  I GR K++II  GGEN+ P
Sbjct: 521 WGRTIFMGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPP 580

Query: 523 AELED 527
             +E+
Sbjct: 581 VPIEE 585



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 57/273 (20%), Positives = 104/273 (38%), Gaps = 26/273 (9%)

Query: 100 LTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQ 159
           ++++Q      +AA G L +GL +   + + G NS  W    + T  AG I+  +     
Sbjct: 133 ISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSS 192

Query: 160 AMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVISV 219
               +Y+        ++   Q + ++   + KQ                 LP L  V+  
Sbjct: 193 PEACQYIAYDCCANVIMVDTQKQLEKILKIWKQ-----------------LPHLKAVVIY 235

Query: 220 DAPLPGTL----LLDEVVAAGS--TRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGA 273
             P P  +     ++E +  G+    + LD +   QQ   C     + +TSGTTG+PKG 
Sbjct: 236 KEPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQC---CVLVYTSGTTGNPKGV 292

Query: 274 TLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILAS 333
            LS  NI   +    +   +     +Q  ++   PL H    +      + +GA +  A 
Sbjct: 293 MLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAE 352

Query: 334 PIFNGKKALEAISRERGTFLYGTPTMFVDILNQ 366
           P       +  +     T   G P ++  I+ +
Sbjct: 353 PDALKGSLVNTLREVEPTSHMGVPRVWEKIMER 385


>gi|227499619 solute carrier family 27 (fatty acid transporter),
           member 2 isoform 1 [Homo sapiens]
          Length = 620

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 123/576 (21%), Positives = 230/576 (39%), Gaps = 76/576 (13%)

Query: 67  KHLNSKTVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLS-IGLCKGD 125
           K   ++T+ +     A++ P +  L  L  D  LT+AQ+    ++ A  L   +GL +GD
Sbjct: 48  KRRPARTILRAFLEKARQTPHKPFL--LFRDETLTYAQVDRRSNQVARALHDHLGLRQGD 105

Query: 126 RLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQ 185
            + +   N  A+V + L   + G  +  +N   +A  L +  +  G K L+         
Sbjct: 106 CVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLL--------- 156

Query: 186 YYNVLKQICPEVENAQPGALKSQRLPDLTTV-ISVDAPLPGTLLLDEVVAAGSTRQHLDQ 244
                  + PE++ A    L S +  D++   +S  +   G     + V   ST    + 
Sbjct: 157 -------VSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPES 209

Query: 245 LQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMI 304
            +    F +   P    +TSGTTG PK A ++H  I   +   G       K  + + + 
Sbjct: 210 WRSEVTFST---PALYIYTSGTTGLPKAAMITHQRIWYGT---GLTFVSGLKADDVIYIT 263

Query: 305 LPNPLYHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMFVDIL 364
           LP   YH    + G   C++ GATL L +  F+  +  +   +   T +     +   + 
Sbjct: 264 LP--FYHSAALLIGIHGCIVAGATLALRTK-FSASQFWDDCRKYNVTVIQYIGELLRYLC 320

Query: 365 N---QPDFSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAHF 421
           N   +P+   + +    G  + G     ++ R  + +     +   Y  TE + + F ++
Sbjct: 321 NSPQKPNDRDHKVRLALGNGLRG-----DVWRQFVKRFGDICIYEFYAATEGN-IGFMNY 374

Query: 422 PEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIR---GYCVML-------- 470
                 +K  +VGR+  + + +I+  +   L K +   +  +R   GYCV +        
Sbjct: 375 A-----RKVGAVGRVN-YLQKKIITYD---LIKYDVEKDEPVRDENGYCVRVPKGEVGLL 425

Query: 471 -----------GYWGEPQKTEEAVDQDK------WYWTGDVATMNEQGFCKIVGRSKDMI 513
                      GY G   +TE+   +D       ++ +GD+  ++ + F     R  D  
Sbjct: 426 VCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTF 485

Query: 514 IRGGENIYPAELEDFFHTHPKVQEVQVVGVK-DDRMGEEICACIRLKDGEETTVEEIKAF 572
              GEN+   E+ D       VQEV V GV   D  G    A I++K+  E   +++   
Sbjct: 486 RWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQH 545

Query: 573 CKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
               +  +  P+++       +T + K +K  L E+
Sbjct: 546 IADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEE 581


>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
           sapiens]
          Length = 686

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 129/553 (23%), Positives = 214/553 (38%), Gaps = 74/553 (13%)

Query: 93  VLHEDVRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILV 152
           V +     T+ ++ E+V K A  L+  G+ KGD + ++ P     +   LA A+ G I  
Sbjct: 137 VTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQAMYTMLACARIGAIHS 196

Query: 153 SVNPAYQAMELEYVLKKVGCKALV---FPKQFKTQQYYNVLKQICPEVENAQPGALKSQR 209
            +   + + EL   +  V  K +V   F  +   +  Y  L +   ++   +P  +    
Sbjct: 197 LIFGGFASKELSSRIDHVKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYN 256

Query: 210 LPDLTTVISVDAPL-PGTLL-LDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTT 267
            P++  V     PL PG  L  DE +A   +   +  L  +        P+ I +TSGTT
Sbjct: 257 RPNMEAV-----PLAPGRDLDWDEEMAKAQSHDCVPVLSEH--------PLYILYTSGTT 303

Query: 268 GSPKG--------ATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGT 319
           G PKG        A + H+++   S+I G +          L  ++ +  Y C G     
Sbjct: 304 GLPKGVIRPTGGYAVMLHWSM---SSIYGLQPGEVWWAASDLGWVVGHS-YICYGP---- 355

Query: 320 MMCLMYGATLILASPIFNGKK-------ALEAISRERGTFLYGTPTMFVDILNQPDFSS- 371
              L++G T +L    + GK        A   +  E G     T    +  + Q D  + 
Sbjct: 356 ---LLHGNTTVL----YEGKPVGTPDAGAYFRVLAEHGVAALFTAPTAIRAIRQQDPGAA 408

Query: 372 ----YDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAHFP-EDTV 426
               Y ++      +AG     E +    N   +  L   + T   SP+T +     ++ 
Sbjct: 409 LGKQYSLTRFKTLFVAGERCDVETLEWSKNVFRVPVLDHWWQTETGSPITASCVGLGNSK 468

Query: 427 EQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIRGYCVML----GYWGEPQKTEEA 482
                  G+ +P     I++     + KL      C+    V L    G +    K +EA
Sbjct: 469 TPPPGQAGKSVPGYNVMILD---DNMQKLKAR---CLGNIVVKLPLPPGAFSGLWKNQEA 522

Query: 483 VDQ------DKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQ 536
                      +Y T D   M+E+G+  ++ R  D+I   G  I    +E+   +H  V 
Sbjct: 523 FKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVINVAGHRISAGAIEESILSHGTVA 582

Query: 537 EVQVVGVKDDRMGE-EICACIRLKD---GEETTVEEIKAFCKGKISHFKIPKYIVFVTNY 592
           +  VVG +D   G   +  C+  KD    EE  +EEI    +  I      +  VFV   
Sbjct: 583 DCAVVGKEDPLKGHVPLALCVLRKDINATEEQVLEEIVKHVRQNIGPVAAFRNAVFVKQL 642

Query: 593 PLTISGKIQKFKL 605
           P T SGKI +  L
Sbjct: 643 PKTRSGKIPRSAL 655


>gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens]
          Length = 672

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 120/553 (21%), Positives = 230/553 (41%), Gaps = 71/553 (12%)

Query: 87  EREALVVLHED----VRLTFAQLKEEVDKAASGLLSIGLCKGDRLGMWGPNSYAWVLMQL 142
           +R AL +  E     V++TF +L++EV   A+ +  +G+ KGDR+  + PNS   V   L
Sbjct: 112 DRVALYIAREGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDRVVGYLPNSEHAVEAML 171

Query: 143 ATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQ---FKTQQYYNVLKQICPEVEN 199
           A A  G I  S +P +    +     ++  K L+F  +   +  +++ ++ K    +V  
Sbjct: 172 AAASIGAIWSSTSPDFGVNGVLDRFSQIQPK-LIFSVEAVVYNGKEHNHMEK--LQQVVK 228

Query: 200 AQPGALKSQRLPDLTTVISVD-APLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPI 258
             P   K   +P +++  ++D + +P ++ LD+ +A G++ Q   QL++ Q  L    P+
Sbjct: 229 GLPDLKKVVVIPYVSSRENIDLSKIPNSVFLDDFLATGTSEQ-APQLEFEQ--LPFSHPL 285

Query: 259 NIQFTSGTTGSPK------GATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHC 312
            I F+SGTTG+PK      G TL  +        L E L     T   + +      Y  
Sbjct: 286 FIMFSSGTTGAPKCMVHSAGGTLIQH--------LKEHLLHGNMTSSDILL-----CYTT 332

Query: 313 LGSVAGTMM--CLMYGATLIL--ASPIFNGKKALEAISRERGTFLYGTPTMFVDILNQ-- 366
           +G +    M   L  GA ++L   SP+      L  +    G  +  T   ++ +L +  
Sbjct: 333 VGWMMWNWMVSLLATGAAMVLYDGSPLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKA 392

Query: 367 -PDFSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAY-GTTENSPVTFAH---F 421
                ++ +  +   +  GSP   +    +   I    L+ +  G T+       H    
Sbjct: 393 MKPVETHSLQMLHTILSTGSPLKAQSYEYVYRCIKSSILLGSISGGTDIISCFMGHNFSL 452

Query: 422 PEDTVEQKAESVGRIMP--HTEARIMNMEAGTLAKLNTPGELCIRGY-CVMLGYWGEPQK 478
           P    E +A ++G  +   + E + +  E+G L        +C +   C    +W +   
Sbjct: 453 PVYKGEIQARNLGMAVEAWNEEGKAVWGESGEL--------VCTKPIPCQPTHFWND--- 501

Query: 479 TEEAVDQDKWYWT--------GDVATMN-EQGFCKIVGRSKDMIIRGGENIYPAELEDFF 529
            E      K Y++        GD   +N + G   ++GRS   +   G     +E+ +  
Sbjct: 502 -ENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIV 560

Query: 530 HTHPKVQEVQVVGVKDDRMGEEICACIRLKDG---EETTVEEIKAFCKGKISHFKIPKYI 586
            +  +V++   V   +    E +   +++  G   +   V+ I+   +  +S   +P  I
Sbjct: 561 ESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLVKRIRDAIRMGLSARHVPSLI 620

Query: 587 VFVTNYPLTISGK 599
           +     P T++GK
Sbjct: 621 LETKGIPYTLNGK 633


>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
           a [Homo sapiens]
          Length = 722

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 44/163 (26%), Positives = 76/163 (46%), Gaps = 5/163 (3%)

Query: 381 VIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHT 440
           V   +PA P ++  +   +  + +   YG TE +       P D     +  VG  +P  
Sbjct: 457 VTGAAPASPTVLGFLRAALGCQ-VYEGYGQTECTAGCTFTTPGDWT---SGHVGAPLPCN 512

Query: 441 EARIMNMEAGTLAKLNTPGELCIRGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQ 500
             +++++E          GE+C+RG  V  GY  +P +T+EA+D D W  TGD+      
Sbjct: 513 HIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPA 572

Query: 501 GFCKIVGRSKDMI-IRGGENIYPAELEDFFHTHPKVQEVQVVG 542
           G  KI+ R K +  +  GE + P ++E+ +     V ++ V G
Sbjct: 573 GTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHG 615



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 14/185 (7%)

Query: 100 LTFAQLKEEVDKAASGLL--SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPA 157
           L++ ++ +  +   SGLL  +   C    +G++  N   W++++LA     +++V +   
Sbjct: 146 LSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDT 205

Query: 158 YQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLTTVI 217
                + Y++       ++  K  K      VL  +   VE  +   LK   L D     
Sbjct: 206 LGPGAIRYIINTADISTVIVDKPQKA-----VL--LLEHVERKETPGLKLIILMDPFEEA 258

Query: 218 SVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQ-FTSGTTGSPKGATLS 276
             +      +++  + A     Q   Q     Q     D ++I  FTSGTTG+PKGA L+
Sbjct: 259 LKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQ----PDDLSIVCFTSGTTGNPKGAMLT 314

Query: 277 HYNIV 281
           H N+V
Sbjct: 315 HGNVV 319


>gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo
           sapiens]
          Length = 720

 Score = 62.8 bits (151), Expect = 9e-10
 Identities = 73/334 (21%), Positives = 132/334 (39%), Gaps = 62/334 (18%)

Query: 260 IQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGT 319
           I +TSG+TG PKG  +SH NI+     + ER+    +  E+   I   PL H L  ++  
Sbjct: 284 IMYTSGSTGLPKGVMISHSNIIAGITGMAERIP---ELGEEDVYIGYLPLAHVL-ELSAE 339

Query: 320 MMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTM-----------FVDILNQ-P 367
           ++CL +G  +  +SP     ++ +     +G      PT+           + +++N+  
Sbjct: 340 LVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVS 399

Query: 368 DFSSYD-------------------------------ISTMCGG----VIAGSPAPPELI 392
           + SS+                                + ++ GG    ++ G        
Sbjct: 400 EMSSFQRNLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATT 459

Query: 393 RAIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTL 452
           +  +N      +   YG TE++    A    +  +     VG  +   E ++ N E G  
Sbjct: 460 QRFMNICFCCPVGQGYGLTESAG---AGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGY 516

Query: 453 AKLNTP---GELCIRGYCVMLGYWGEPQKTEEAVDQD----KWYWTGDVATMNEQGFCKI 505
              + P   GE+ I G  V +GY+    KT+    +D    +W  TGD+      G  KI
Sbjct: 517 FNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKI 576

Query: 506 VGRSKDMI-IRGGENIYPAELEDFFHTHPKVQEV 538
           + R KD++ ++ GE +   ++E      P V  +
Sbjct: 577 IDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNI 610


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,184,752
Number of Sequences: 37866
Number of extensions: 1038843
Number of successful extensions: 2275
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2148
Number of HSP's gapped (non-prelim): 78
length of query: 615
length of database: 18,247,518
effective HSP length: 108
effective length of query: 507
effective length of database: 14,157,990
effective search space: 7178100930
effective search space used: 7178100930
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.